-- dump date   	20140620_045744
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
550537000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
550537000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
550537000003	putative catalytic residues [active]
550537000004	putative nucleotide binding site [chemical binding]; other site
550537000005	putative aspartate binding site [chemical binding]; other site
550537000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
550537000007	dimer interface [polypeptide binding]; other site
550537000008	putative threonine allosteric regulatory site; other site
550537000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
550537000010	putative threonine allosteric regulatory site; other site
550537000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
550537000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
550537000013	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 2.4e-63
550537000014	PS00324 Aspartokinase signature.
550537000015	HMMPfam hit to PF01842, Amino acid-binding ACT, score 1.2e-05
550537000016	HMMPfam hit to PF01842, Amino acid-binding ACT, score 3.8e-07
550537000017	HMMPfam hit to PF03447, Aspartate/homoserine dehydrogenase, NAD-binding, score 5.7e-47
550537000018	HMMPfam hit to PF00742, Homoserine dehydrogenase, catalytic, score 9.2e-101
550537000019	PS01042 Homoserine dehydrogenase signature.
550537000020	homoserine kinase; Provisional; Region: PRK01212
550537000021	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
550537000022	HMMPfam hit to PF00288, GHMP kinase, score 1.8e-20
550537000023	PS00627 GHMP kinases  ATP-binding domain.
550537000024	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000025	HMMPfam hit to PF08544, GHMP kinase, C-terminal, score 4.9e-11
550537000026	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
550537000027	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
550537000028	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537000029	catalytic residue [active]
550537000030	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 5.5e-31
550537000031	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
550537000032	hypothetical protein; Validated; Region: PRK02101
550537000033	HMMPfam hit to PF03883, Protein of unknown function DUF328, score 6.4e-176
550537000034	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537000035	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
550537000036	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
550537000037	HMMPfam hit to PF01235, Sodium:alanine symporter, score 1.8e-239
550537000038	9 probable transmembrane helices predicted for SEN0005 by TMHMM2.0 at aa 13-35, 75-97, 136-158, 171-193, 203-225, 301-323, 343-365, 386-408 and 413-435
550537000039	PS00041 Bacterial regulatory proteins, araC family signature.
550537000040	PS00873 Sodium:alanine symporter family signature.
550537000041	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000042	transaldolase-like protein; Provisional; Region: PTZ00411
550537000043	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
550537000044	active site
550537000045	dimer interface [polypeptide binding]; other site
550537000046	catalytic residue [active]
550537000047	HMMPfam hit to PF00923, Transaldolase, score 2.4e-187
550537000048	PS01054 Transaldolase signature 1.
550537000049	PS00958 Transaldolase active site.
550537000050	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
550537000051	MPT binding site; other site
550537000052	trimer interface [polypeptide binding]; other site
550537000053	HMMPfam hit to PF00994, Molybdopterin binding, score 5.3e-31
550537000054	PS01078 Molybdenum cofactor biosynthesis proteins signature 1.
550537000055	hypothetical protein; Provisional; Region: PRK10659
550537000056	HMMPfam hit to PF01184, GPR1/FUN34/yaaH, score 3.7e-118
550537000057	6 probable transmembrane helices predicted for SEN0008 by TMHMM2.0 at aa 12-34, 38-57, 64-86, 96-118, 125-144 and 148-170
550537000058	PS01114 GPR1/FUN34/yaaH family signature.
550537000059	hypothetical protein; Provisional; Region: PRK10236
550537000060	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
550537000061	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
550537000062	HMMPfam hit to PF03667, Protein of unknown function UPF0174, score 2e-125
550537000063	hypothetical protein; Provisional; Region: PRK10154
550537000064	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
550537000065	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
550537000066	nucleotide binding site [chemical binding]; other site
550537000067	HMMPfam hit to PF00012, Heat shock protein 70, score 0
550537000068	PS00297 Heat shock hsp70 proteins family signature 1.
550537000069	PS00329 Heat shock hsp70 proteins family signature 2.
550537000070	PS01036 Heat shock hsp70 proteins family signature 3.
550537000071	chaperone protein DnaJ; Provisional; Region: PRK10767
550537000072	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
550537000073	HSP70 interaction site [polypeptide binding]; other site
550537000074	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
550537000075	substrate binding site [polypeptide binding]; other site
550537000076	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
550537000077	Zn binding sites [ion binding]; other site
550537000078	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
550537000079	dimer interface [polypeptide binding]; other site
550537000080	HMMPfam hit to PF00226, Heat shock protein DnaJ, N-terminal, score 4e-40
550537000081	PS00636 Nt-dnaJ domain signature.
550537000082	HMMPfam hit to PF00684, DnaJ central region, score 1.8e-50
550537000083	PS00637 CXXCXGXG dnaJ domain signature.
550537000084	PS00190 Cytochrome c family heme-binding site signature.
550537000085	HMMPfam hit to PF01556, Chaperone DnaJ, C-terminal, score 1.1e-76
550537000086	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537000087	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537000088	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
550537000089	substrate binding pocket [chemical binding]; other site
550537000090	dimerization interface [polypeptide binding]; other site
550537000091	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 4.8e-14
550537000092	3 probable transmembrane helices predicted for SEN0014 by TMHMM2.0 at aa 15-37, 50-72 and 82-101
550537000093	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
550537000094	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
550537000095	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
550537000096	HMMPfam hit to PF05838, Protein of unknown function DUF847, score 1.2e-102
550537000097	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
550537000098	1 probable transmembrane helix predicted for SEN0016 by TMHMM2.0 at aa 127-146
550537000099	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
550537000100	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
550537000101	active site
550537000102	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
550537000103	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
550537000104	aromatic chitin/cellulose binding site residues [chemical binding]; other site
550537000105	HMMPfam hit to PF00704, Glycoside hydrolase, family 18, catalytic domain, score 3.2e-68
550537000106	HMMPfam hit to PF02839, Carbohydrate-binding family V/XII, score 3.9e-07
550537000107	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
550537000108	Helix-turn-helix domain; Region: HTH_36; pfam13730
550537000109	fimbrial operon bcf
550537000110	fimbrial protein BcfA; Provisional; Region: PRK15187
550537000111	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 4.5e-43
550537000112	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
550537000113	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537000114	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537000115	1 probable transmembrane helix predicted for SEN0021 by TMHMM2.0 at aa 7-29
550537000116	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 2.3e-51
550537000117	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
550537000118	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 4.3e-08
550537000119	outer membrane usher protein; Provisional; Region: PRK15193
550537000120	PapC N-terminal domain; Region: PapC_N; pfam13954
550537000121	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537000122	PapC C-terminal domain; Region: PapC_C; pfam13953
550537000123	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537000124	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000125	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537000126	fimbrial protein BcfD; Provisional; Region: PRK15189
550537000127	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.0025
550537000128	fimbrial protein BcfE; Provisional; Region: PRK15190
550537000129	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 2.1e-28
550537000130	fimbrial protein BcfF; Provisional; Region: PRK15191
550537000131	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 8.1e-43
550537000132	fimbrial chaperone BcfG; Provisional; Region: PRK15192
550537000133	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537000134	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537000135	1 probable transmembrane helix predicted for SEN0026 by TMHMM2.0 at aa 13-35
550537000136	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 3.7e-35
550537000137	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 9.4e-11
550537000138	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
550537000139	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
550537000140	catalytic residues [active]
550537000141	HMMPfam hit to PF01323, DSBA oxidoreductase, score 4.9e-11
550537000142	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
550537000143	1 probable transmembrane helix predicted for SEN0029 by TMHMM2.0 at aa 128-147
550537000144	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 2.4e-06
550537000145	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537000146	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537000147	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537000148	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 8.2e-16
550537000149	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
550537000150	1 probable transmembrane helix predicted for SEN0031 by TMHMM2.0 at aa 128-145
550537000151	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
550537000152	HMMPfam hit to PF05935, Arylsulphotransferase, score 0
550537000153	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000154	PS00061 Short-chain dehydrogenases/reductases family signature.
550537000155	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
550537000156	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
550537000157	active site
550537000158	metal binding site [ion binding]; metal-binding site
550537000159	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
550537000160	HMMPfam hit to PF02872, 5'-Nucleotidase, C-terminal, score 3.4e-44
550537000161	HMMPfam hit to PF00149, Metallophosphoesterase, score 2.5e-16
550537000162	PS00786 5'-nucleotidase signature 2.
550537000163	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
550537000164	HMMPfam hit to PF07135, Protein of unknown function DUF1384, score 3.5e-194
550537000165	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000166	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
550537000167	Sulfatase; Region: Sulfatase; pfam00884
550537000168	1 probable transmembrane helix predicted for SEN0035 by TMHMM2.0 at aa 5-27
550537000169	HMMPfam hit to PF00884, Sulphatase, score 6e-61
550537000170	PS00523 Sulfatases signature 1.
550537000171	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
550537000172	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537000173	FeS/SAM binding site; other site
550537000174	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
550537000175	HMMPfam hit to PF04055, Radical SAM, score 3.3e-14
550537000176	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
550537000177	PS00280 Pancreatic trypsin inhibitor (Kunitz) family signature.
550537000178	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
550537000179	HMMPfam hit to PF05935, Arylsulphotransferase, score 0
550537000180	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
550537000181	HMMPfam hit to PF06965, Na+/H+ antiporter NhaA, score 4.8e-258
550537000182	11 probable transmembrane helices predicted for SEN0039 by TMHMM2.0 at aa 7-29, 59-76, 96-115, 125-147, 154-176, 180-202, 215-237, 257-279, 291-313, 328-350 and 357-379
550537000183	PS00044 Bacterial regulatory proteins, lysR family signature.
550537000184	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
550537000185	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537000186	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
550537000187	putative dimerization interface [polypeptide binding]; other site
550537000188	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 3.6e-18
550537000189	PS00044 Bacterial regulatory proteins, lysR family signature.
550537000190	PS00027 'Homeobox' domain signature.
550537000191	putative alpha-glucosidase; Provisional; Region: PRK10658
550537000192	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
550537000193	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
550537000194	putative active site [active]
550537000195	putative catalytic site [active]
550537000196	HMMPfam hit to PF01055, Glycoside hydrolase, family 31, score 1.1e-173
550537000197	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
550537000198	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
550537000199	11 probable transmembrane helices predicted for SEN0042 by TMHMM2.0 at aa 42-64, 92-109, 124-146, 167-184, 189-211, 240-257, 277-299, 306-326, 336-358, 371-396 and 416-438
550537000200	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000201	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000202	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
550537000203	HMMPfam hit to PF01649, Ribosomal protein S20, score 2.4e-44
550537000204	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
550537000205	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
550537000206	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
550537000207	active site
550537000208	Riboflavin kinase; Region: Flavokinase; smart00904
550537000209	HMMPfam hit to PF06574, FAD synthetase, score 9.2e-86
550537000210	HMMPfam hit to PF01687, Riboflavin kinase, score 3.5e-66
550537000211	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
550537000212	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
550537000213	active site
550537000214	HIGH motif; other site
550537000215	nucleotide binding site [chemical binding]; other site
550537000216	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
550537000217	active site
550537000218	KMSKS motif; other site
550537000219	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
550537000220	tRNA binding surface [nucleotide binding]; other site
550537000221	anticodon binding site; other site
550537000222	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
550537000223	HMMPfam hit to PF00133, Aminoacyl-tRNA synthetase, class Ia, score 0
550537000224	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537000225	HMMPfam hit to PF08264, Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding, score 3.7e-55
550537000226	HMMPfam hit to PF06827, Formamidopyrimidine-DNA glycolase, C-terminal, score 1.9e-13
550537000227	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
550537000228	HMMPfam hit to PF01252, Peptidase A8, signal peptidase II, score 2.8e-86
550537000229	4 probable transmembrane helices predicted for SEN0047 by TMHMM2.0 at aa 13-35, 67-86, 99-121 and 136-158
550537000230	PS00855 Signal peptidases II signature.
550537000231	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
550537000232	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
550537000233	HMMPfam hit to PF00254, Peptidyl-prolyl cis-trans isomerase, FKBP-type, score 9.1e-13
550537000234	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
550537000235	PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2.
550537000236	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
550537000237	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
550537000238	HMMPfam hit to PF02401, LytB protein, score 1.3e-188
550537000239	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
550537000240	active site
550537000241	tetramer interface [polypeptide binding]; other site
550537000242	HMMPfam hit to PF01156, Inosine/uridine-preferring nucleoside hydrolase, score 1.4e-148
550537000243	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
550537000244	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537000245	active site
550537000246	phosphorylation site [posttranslational modification]
550537000247	intermolecular recognition site; other site
550537000248	dimerization interface [polypeptide binding]; other site
550537000249	Transcriptional regulator; Region: CitT; pfam12431
550537000250	HMMPfam hit to PF00072, Response regulator receiver, score 2.9e-21
550537000251	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
550537000252	PAS domain; Region: PAS; smart00091
550537000253	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537000254	ATP binding site [chemical binding]; other site
550537000255	Mg2+ binding site [ion binding]; other site
550537000256	G-X-G motif; other site
550537000257	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 4.7e-24
550537000258	2 probable transmembrane helices predicted for SEN0054 by TMHMM2.0 at aa 20-39 and 173-195
550537000259	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000260	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
550537000261	9 probable transmembrane helices predicted for SEN0055 by TMHMM2.0 at aa 13-35, 42-64, 125-147, 160-182, 214-236, 266-288, 308-327, 339-361 and 409-431
550537000262	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit, score 5.1e-288
550537000263	oxaloacetate decarboxylase; Provisional; Region: PRK14040
550537000264	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
550537000265	active site
550537000266	catalytic residues [active]
550537000267	metal binding site [ion binding]; metal-binding site
550537000268	homodimer binding site [polypeptide binding]; other site
550537000269	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
550537000270	carboxyltransferase (CT) interaction site; other site
550537000271	biotinylation site [posttranslational modification]; other site
550537000272	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 8.9e-28
550537000273	PS00188 Biotin-requiring enzymes attachment site.
550537000274	HMMPfam hit to PF02436, Conserved carboxylase region, score 3.7e-99
550537000275	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
550537000276	HMMPfam hit to PF00682, Pyruvate carboxyltransferase, score 3.3e-90
550537000277	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
550537000278	HMMPfam hit to PF04277, Sodium ion-translocating decarboxylase, score 5.8e-31
550537000279	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
550537000280	12 probable transmembrane helices predicted for SEN0058 by TMHMM2.0 at aa 23-45, 52-69, 79-101, 114-132, 147-169, 176-198, 208-230, 269-286, 296-318, 331-348, 363-385 and 425-444
550537000281	HMMPfam hit to PF03390, Citrate carrier protein, score 1.9e-277
550537000282	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
550537000283	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
550537000284	putative active site [active]
550537000285	(T/H)XGH motif; other site
550537000286	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 2.3e-06
550537000287	HMMPfam hit to PF08218, Citrate lyase ligase, C-terminal, score 2.8e-136
550537000288	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
550537000289	HMMPfam hit to PF04953, Citrate lyase acyl carrier protein CitD, score 8.7e-60
550537000290	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
550537000291	HMMPfam hit to PF03328, HpcH/HpaI aldolase, score 3.9e-110
550537000292	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000293	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
550537000294	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
550537000295	HMMPfam hit to PF04223, Citrate lyase, alpha subunit, score 0
550537000296	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000297	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
550537000298	HMMPfam hit to PF03802, Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, score 5.3e-52
550537000299	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
550537000300	HMMPfam hit to PF01874, Triphosphoribosyl-dephospho-CoA protein, score 1.2e-123
550537000301	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
550537000302	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
550537000303	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
550537000304	HMMPfam hit to PF01113, Dihydrodipicolinate reductase, score 7.1e-65
550537000305	HMMPfam hit to PF05173, Dihydrodipicolinate reductase, score 1e-81
550537000306	PS01298 Dihydrodipicolinate reductase signature.
550537000307	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
550537000308	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
550537000309	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
550537000310	catalytic site [active]
550537000311	subunit interface [polypeptide binding]; other site
550537000312	HMMPfam hit to PF00988, Carbamoyl-phosphate synthase, small chain, score 1.5e-95
550537000313	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 5.6e-75
550537000314	PS00442 Glutamine amidotransferases class-I active site.
550537000315	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
550537000316	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
550537000317	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
550537000318	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
550537000319	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
550537000320	ATP-grasp domain; Region: ATP-grasp_4; cl17255
550537000321	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
550537000322	IMP binding site; other site
550537000323	dimer interface [polypeptide binding]; other site
550537000324	interdomain contacts; other site
550537000325	partial ornithine binding site; other site
550537000326	HMMPfam hit to PF00289, Carbamoyl-phosphate synthetase large chain, N-terminal, score 6.5e-64
550537000327	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000328	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP-binding, score 2.2e-146
550537000329	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
550537000330	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
550537000331	HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large chain, oligomerisation, score 2e-68
550537000332	HMMPfam hit to PF00289, Carbamoyl-phosphate synthetase large chain, N-terminal, score 2.9e-26
550537000333	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP-binding, score 3.8e-18
550537000334	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
550537000335	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP-binding, score 1.7e-14
550537000336	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
550537000337	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000338	HMMPfam hit to PF02142, MGS-like, score 7.4e-31
550537000339	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
550537000340	carnitine operon protein CaiE; Provisional; Region: PRK13627
550537000341	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
550537000342	putative trimer interface [polypeptide binding]; other site
550537000343	putative metal binding site [ion binding]; other site
550537000344	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.015
550537000345	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 31
550537000346	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1.1
550537000347	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
550537000348	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
550537000349	substrate binding site [chemical binding]; other site
550537000350	oxyanion hole (OAH) forming residues; other site
550537000351	trimer interface [polypeptide binding]; other site
550537000352	HMMPfam hit to PF00378, Crotonase, core, score 9.3e-85
550537000353	PS00166 Enoyl-CoA hydratase/isomerase signature.
550537000354	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
550537000355	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
550537000356	acyl-activating enzyme (AAE) consensus motif; other site
550537000357	putative AMP binding site [chemical binding]; other site
550537000358	putative active site [active]
550537000359	putative CoA binding site [chemical binding]; other site
550537000360	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 2.3e-123
550537000361	PS00455  AMP-binding domain signature.
550537000362	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
550537000363	CoA-transferase family III; Region: CoA_transf_3; pfam02515
550537000364	HMMPfam hit to PF02515, CoA-transferase family III, score 2.8e-99
550537000365	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
550537000366	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
550537000367	active site
550537000368	HMMPfam hit to PF00441, Acyl-CoA oxidase/dehydrogenase, type 1, score 1.9e-59
550537000369	PS00073 Acyl-CoA dehydrogenases signature 2.
550537000370	HMMPfam hit to PF02770, Acyl-CoA dehydrogenase/oxidase, central region, score 1.4e-16
550537000371	PS00072 Acyl-CoA dehydrogenases signature 1.
550537000372	HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal, score 2e-50
550537000373	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
550537000374	HMMPfam hit to PF02028, BCCT transporter, score 4.7e-304
550537000375	12 probable transmembrane helices predicted for SEN0075 by TMHMM2.0 at aa 13-30, 50-72, 92-114, 144-163, 195-214, 229-251, 264-286, 312-334, 347-366, 410-432, 445-467 and 472-494
550537000376	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000377	PS01303 BCCT family of transporters signature.
550537000378	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000379	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
550537000380	Ligand binding site [chemical binding]; other site
550537000381	Electron transfer flavoprotein domain; Region: ETF; pfam01012
550537000382	HMMPfam hit to PF01012, Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, score 2.4e-62
550537000383	PS01065 Electron transfer flavoprotein beta-subunit signature.
550537000384	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
550537000385	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
550537000386	Ligand binding site [chemical binding]; other site
550537000387	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
550537000388	HMMPfam hit to PF01012, Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, score 7.3e-38
550537000389	HMMPfam hit to PF00766, Electron transfer flavoprotein, alpha subunit, C-terminal, score 7.2e-43
550537000390	PS00696 Electron transfer flavoprotein alpha-subunit signature.
550537000391	putative oxidoreductase FixC; Provisional; Region: PRK10157
550537000392	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.2e-14
550537000393	ferredoxin-like protein FixX; Provisional; Region: PRK15449
550537000394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537000395	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
550537000396	putative substrate translocation pore; other site
550537000397	11 probable transmembrane helices predicted for SEN0080 by TMHMM2.0 at aa 19-41, 54-76, 85-104, 109-131, 144-166, 171-193, 244-266, 281-303, 324-346, 372-394 and 399-421
550537000398	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 8.5e-35
550537000399	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000400	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
550537000401	HMMPfam hit to PF06004, Protein of unknown function DUF903, bacterial, score 3.2e-45
550537000402	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000403	PS00294 Prenyl group binding site (CAAX box).
550537000404	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537000405	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 1.5e-25
550537000406	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
550537000407	Sulfatase; Region: Sulfatase; cl17466
550537000408	Sulfatase; Region: Sulfatase; cl17466
550537000409	Sulfatase; Region: Sulfatase; cl17466
550537000410	HMMPfam hit to PF00884, Sulphatase, score 1e-19
550537000411	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
550537000412	HMMPfam hit to PF02525, Flavodoxin-like fold, score 2.9e-49
550537000413	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
550537000414	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
550537000415	TrkA-N domain; Region: TrkA_N; pfam02254
550537000416	13 probable transmembrane helices predicted for SEN0088 by TMHMM2.0 at aa 5-24, 26-45, 55-74, 86-108, 112-134, 147-169, 179-201, 214-233, 237-254, 267-289, 293-315, 327-349 and 359-378
550537000417	HMMPfam hit to PF00999, Sodium/hydrogen exchanger, score 3.3e-65
550537000418	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000419	HMMPfam hit to PF02254, TrkA-N, score 2.3e-36
550537000420	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
550537000421	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
550537000422	folate binding site [chemical binding]; other site
550537000423	NADP+ binding site [chemical binding]; other site
550537000424	HMMPfam hit to PF00186, Dihydrofolate reductase region, score 7.1e-58
550537000425	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537000426	PS00075 Dihydrofolate reductase signature.
550537000427	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
550537000428	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
550537000429	active site
550537000430	metal binding site [ion binding]; metal-binding site
550537000431	HMMPfam hit to PF00149, Metallophosphoesterase, score 4.7e-18
550537000432	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
550537000433	HMMPfam hit to PF04379, ApaG, score 4.4e-78
550537000434	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
550537000435	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
550537000436	HMMPfam hit to PF00398, Ribosomal RNA adenine methylase transferase, score 7.4e-104
550537000437	PS01131 Ribosomal RNA adenine dimethylases signature.
550537000438	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
550537000439	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
550537000440	HMMPfam hit to PF04166, Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA, score 3.1e-183
550537000441	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
550537000442	SurA N-terminal domain; Region: SurA_N; pfam09312
550537000443	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
550537000444	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
550537000445	HMMPfam hit to PF00639, Peptidyl-prolyl cis-trans isomerase, PpiC-type, score 5.2e-50
550537000446	PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature.
550537000447	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000448	HMMPfam hit to PF00639, Peptidyl-prolyl cis-trans isomerase, PpiC-type, score 9.3e-43
550537000449	PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature.
550537000450	HMMPfam hit to PF09312, SurA N-terminal domain, score 6.3e-90
550537000451	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
550537000452	OstA-like protein; Region: OstA; pfam03968
550537000453	Organic solvent tolerance protein; Region: OstA_C; pfam04453
550537000454	HMMPfam hit to PF04453, Organic solvent tolerance protein, score 5.6e-150
550537000455	HMMPfam hit to PF03968, OstA-like protein, score 2.1e-68
550537000456	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
550537000457	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
550537000458	putative metal binding site [ion binding]; other site
550537000459	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
550537000460	HSP70 interaction site [polypeptide binding]; other site
550537000461	1 probable transmembrane helix predicted for SEN0096 by TMHMM2.0 at aa 7-29
550537000462	HMMPfam hit to PF00226, Heat shock protein DnaJ, N-terminal, score 1.1e-11
550537000463	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
550537000464	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
550537000465	active site
550537000466	HMMPfam hit to PF00849, Pseudouridine synthase, score 7.6e-61
550537000467	PS01129 Rlu family of pseudouridine synthase signature.
550537000468	ATP-dependent helicase HepA; Validated; Region: PRK04914
550537000469	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537000470	ATP binding site [chemical binding]; other site
550537000471	putative Mg++ binding site [ion binding]; other site
550537000472	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537000473	nucleotide binding region [chemical binding]; other site
550537000474	ATP-binding site [chemical binding]; other site
550537000475	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 4.7e-20
550537000476	HMMPfam hit to PF00176, SNF2-related, score 6.3e-85
550537000477	DNA polymerase II; Reviewed; Region: PRK05762
550537000478	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
550537000479	active site
550537000480	catalytic site [active]
550537000481	substrate binding site [chemical binding]; other site
550537000482	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
550537000483	active site
550537000484	metal-binding site
550537000485	HMMPfam hit to PF00136, DNA polymerase, B region, score 8.2e-33
550537000486	PS00116 DNA polymerase family B signature.
550537000487	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000488	HMMPfam hit to PF03104, DNA polymerase B, exonuclease, score 3.3e-55
550537000489	Uncharacterized conserved protein [Function unknown]; Region: COG1434
550537000490	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
550537000491	putative active site [active]
550537000492	HMMPfam hit to PF02698, Protein of unknown function DUF218, score 8.2e-54
550537000493	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000494	1 probable transmembrane helix predicted for SEN0100 by TMHMM2.0 at aa 5-27
550537000495	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
550537000496	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
550537000497	intersubunit interface [polypeptide binding]; other site
550537000498	active site
550537000499	Zn2+ binding site [ion binding]; other site
550537000500	HMMPfam hit to PF00596, Class II aldolase/adducin, N-terminal, score 3.1e-105
550537000501	L-arabinose isomerase; Provisional; Region: PRK02929
550537000502	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
550537000503	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
550537000504	trimer interface [polypeptide binding]; other site
550537000505	putative substrate binding site [chemical binding]; other site
550537000506	putative metal binding site [ion binding]; other site
550537000507	HMMPfam hit to PF02610, L-arabinose isomerase, score 0
550537000508	ribulokinase; Provisional; Region: PRK04123
550537000509	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
550537000510	N- and C-terminal domain interface [polypeptide binding]; other site
550537000511	active site
550537000512	MgATP binding site [chemical binding]; other site
550537000513	catalytic site [active]
550537000514	metal binding site [ion binding]; metal-binding site
550537000515	carbohydrate binding site [chemical binding]; other site
550537000516	homodimer interface [polypeptide binding]; other site
550537000517	HMMPfam hit to PF02782, Carbohydrate kinase, FGGY, score 2.2e-06
550537000518	HMMPfam hit to PF00370, Carbohydrate kinase, FGGY, score 3.6e-06
550537000519	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
550537000520	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
550537000521	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537000522	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537000523	HMMPfam hit to PF02311, AraC protein, arabinose-binding/dimerisation, score 3.3e-29
550537000524	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.6e-11
550537000525	PS00041 Bacterial regulatory proteins, araC family signature.
550537000526	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 4.8e-12
550537000527	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
550537000528	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
550537000529	5 probable transmembrane helices predicted for SEN0106 by TMHMM2.0 at aa 13-35, 57-79, 140-162, 177-199 and 219-241
550537000530	HMMPfam hit to PF09335, SNARE associated Golgi protein, score 0.00014
550537000531	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000532	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
550537000533	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
550537000534	Walker A/P-loop; other site
550537000535	ATP binding site [chemical binding]; other site
550537000536	Q-loop/lid; other site
550537000537	ABC transporter signature motif; other site
550537000538	Walker B; other site
550537000539	D-loop; other site
550537000540	H-loop/switch region; other site
550537000541	HMMPfam hit to PF00005, ABC transporter related, score 3.6e-64
550537000542	PS00211 ABC transporters family signature.
550537000543	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000544	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
550537000545	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537000546	dimer interface [polypeptide binding]; other site
550537000547	conserved gate region; other site
550537000548	putative PBP binding loops; other site
550537000549	ABC-ATPase subunit interface; other site
550537000550	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537000551	dimer interface [polypeptide binding]; other site
550537000552	conserved gate region; other site
550537000553	putative PBP binding loops; other site
550537000554	ABC-ATPase subunit interface; other site
550537000555	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 0.002
550537000556	12 probable transmembrane helices predicted for SEN0108 by TMHMM2.0 at aa 13-35, 55-77, 90-112, 127-149, 199-221, 241-260, 293-315, 335-357, 370-392, 407-424, 462-484 and 508-525
550537000557	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.6e-07
550537000558	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
550537000559	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
550537000560	PS01037 Bacterial extracellular solute-binding proteins, family 1 signature.
550537000561	transcriptional regulator SgrR; Provisional; Region: PRK13626
550537000562	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
550537000563	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
550537000564	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 2.7e-49
550537000565	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
550537000566	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
550537000567	substrate binding site [chemical binding]; other site
550537000568	HMMPfam hit to PF00694, Aconitase A/isopropylmalate dehydratase small subunit, swivel, score 1.4e-65
550537000569	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
550537000570	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
550537000571	substrate binding site [chemical binding]; other site
550537000572	ligand binding site [chemical binding]; other site
550537000573	HMMPfam hit to PF00330, Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, score 1.1e-285
550537000574	PS01244 Aconitase family signature 2.
550537000575	PS00450 Aconitase family signature 1.
550537000576	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
550537000577	tartrate dehydrogenase; Region: TTC; TIGR02089
550537000578	HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 1.7e-226
550537000579	PS00470 Isocitrate and isopropylmalate dehydrogenases signature.
550537000580	2-isopropylmalate synthase; Validated; Region: PRK00915
550537000581	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
550537000582	active site
550537000583	catalytic residues [active]
550537000584	metal binding site [ion binding]; metal-binding site
550537000585	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
550537000586	HMMPfam hit to PF08502, LeuA allosteric (dimerisation) domain, score 2.9e-63
550537000587	HMMPfam hit to PF00682, Pyruvate carboxyltransferase, score 5.4e-151
550537000588	PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2.
550537000589	PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1.
550537000590	leu operon leader peptide; Provisional; Region: PRK14744
550537000591	HMMPfam hit to PF08054, Leucine operon leader peptide, score 6.6e-16
550537000592	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
550537000593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537000594	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
550537000595	putative substrate binding pocket [chemical binding]; other site
550537000596	putative dimerization interface [polypeptide binding]; other site
550537000597	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2.1e-19
550537000598	PS00044 Bacterial regulatory proteins, lysR family signature.
550537000599	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.6e-08
550537000600	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
550537000601	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
550537000602	dimer interface [polypeptide binding]; other site
550537000603	PYR/PP interface [polypeptide binding]; other site
550537000604	TPP binding site [chemical binding]; other site
550537000605	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
550537000606	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
550537000607	TPP-binding site [chemical binding]; other site
550537000608	dimer interface [polypeptide binding]; other site
550537000609	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding region, score 5.3e-88
550537000610	PS00044 Bacterial regulatory proteins, lysR family signature.
550537000611	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central region, score 1e-66
550537000612	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000613	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding, score 2e-77
550537000614	PS00187 Thiamine pyrophosphate enzymes signature.
550537000615	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
550537000616	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
550537000617	putative valine binding site [chemical binding]; other site
550537000618	dimer interface [polypeptide binding]; other site
550537000619	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
550537000620	PS00430 TonB-dependent receptor proteins signature 1.
550537000621	HMMPfam hit to PF01842, Amino acid-binding ACT, score 3.9e-13
550537000622	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
550537000623	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537000624	DNA binding site [nucleotide binding]
550537000625	domain linker motif; other site
550537000626	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
550537000627	dimerization interface [polypeptide binding]; other site
550537000628	ligand binding site [chemical binding]; other site
550537000629	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 3.6e-10
550537000630	PS00356 Bacterial regulatory proteins, lacI family signature.
550537000631	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 7.6e-07
550537000632	mraZ protein; Region: TIGR00242
550537000633	MraZ protein; Region: MraZ; pfam02381
550537000634	MraZ protein; Region: MraZ; pfam02381
550537000635	HMMPfam hit to PF02381, MraZ, score 4.1e-29
550537000636	HMMPfam hit to PF02381, MraZ, score 1.3e-23
550537000637	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
550537000638	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
550537000639	HMMPfam hit to PF01795, Bacterial methyltransferase, score 2.4e-193
550537000640	cell division protein FtsL; Provisional; Region: PRK10772
550537000641	HMMPfam hit to PF04999, Cell division protein FtsL, score 1.2e-65
550537000642	1 probable transmembrane helix predicted for SEN0122 by TMHMM2.0 at aa 35-57
550537000643	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
550537000644	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
550537000645	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
550537000646	1 probable transmembrane helix predicted for SEN0123 by TMHMM2.0 at aa 21-43
550537000647	HMMPfam hit to PF03717, Penicillin-binding protein, dimerisation domain, score 1.5e-67
550537000648	HMMPfam hit to PF00905, Penicillin-binding protein, transpeptidase, score 5e-120
550537000649	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
550537000650	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
550537000651	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
550537000652	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
550537000653	HMMPfam hit to PF01225, Mur ligase, N-terminal, score 1.9e-15
550537000654	HMMPfam hit to PF08245, Mur ligase, central, score 1.1e-75
550537000655	HMMPfam hit to PF02875, Mur ligase, C-terminal, score 8.3e-40
550537000656	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
550537000657	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
550537000658	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
550537000659	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
550537000660	HMMPfam hit to PF01225, Mur ligase, N-terminal, score 7.3e-22
550537000661	HMMPfam hit to PF08245, Mur ligase, central, score 5.9e-70
550537000662	HMMPfam hit to PF02875, Mur ligase, C-terminal, score 4.6e-18
550537000663	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
550537000664	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
550537000665	Mg++ binding site [ion binding]; other site
550537000666	putative catalytic motif [active]
550537000667	putative substrate binding site [chemical binding]; other site
550537000668	10 probable transmembrane helices predicted for SEN0126 by TMHMM2.0 at aa 15-37, 75-92, 97-114, 134-151, 171-193, 200-219, 234-256, 263-285, 289-311 and 338-357
550537000669	HMMPfam hit to PF00953, Glycosyl transferase, family 4, score 2.9e-86
550537000670	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
550537000671	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
550537000672	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
550537000673	1 probable transmembrane helix predicted for SEN0127 by TMHMM2.0 at aa 9-31
550537000674	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000675	HMMPfam hit to PF08245, Mur ligase, central, score 2.8e-60
550537000676	PS00012 Phosphopantetheine attachment site.
550537000677	HMMPfam hit to PF02875, Mur ligase, C-terminal, score 9.4e-14
550537000678	cell division protein FtsW; Provisional; Region: PRK10774
550537000679	HMMPfam hit to PF01098, Cell cycle protein, score 4.9e-190
550537000680	8 probable transmembrane helices predicted for SEN0128 by TMHMM2.0 at aa 20-42, 57-74, 81-103, 155-177, 190-212, 278-300, 312-334 and 344-366
550537000681	PS00428 Cell cycle proteins ftsW / rodA / spoVE signature.
550537000682	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
550537000683	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
550537000684	active site
550537000685	homodimer interface [polypeptide binding]; other site
550537000686	HMMPfam hit to PF03033, Glycosyl transferase, family 28, score 1.7e-52
550537000687	HMMPfam hit to PF04101, Glycosyltransferase 28, C-terminal, score 6.5e-57
550537000688	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
550537000689	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
550537000690	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
550537000691	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
550537000692	HMMPfam hit to PF01225, Mur ligase, N-terminal, score 1.1e-47
550537000693	HMMPfam hit to PF08245, Mur ligase, central, score 1e-35
550537000694	HMMPfam hit to PF02875, Mur ligase, C-terminal, score 2.1e-23
550537000695	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
550537000696	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
550537000697	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
550537000698	HMMPfam hit to PF01820, D-alanine--D-alanine ligase, N-terminal, score 2.7e-55
550537000699	PS00843 D-alanine--D-alanine ligase signature 1.
550537000700	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537000701	HMMPfam hit to PF07478, D-alanine--D-alanine ligase, C-terminal, score 2.2e-110
550537000702	PS00844 D-alanine--D-alanine ligase signature 2.
550537000703	cell division protein FtsQ; Provisional; Region: PRK10775
550537000704	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
550537000705	Cell division protein FtsQ; Region: FtsQ; pfam03799
550537000706	1 probable transmembrane helix predicted for SEN0132 by TMHMM2.0 at aa 26-48
550537000707	HMMPfam hit to PF08478, Polypeptide-transport-associated, FtsQ-type, score 1.2e-24
550537000708	HMMPfam hit to PF03799, Cell division protein FtsQ, score 7.5e-36
550537000709	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
550537000710	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537000711	Cell division protein FtsA; Region: FtsA; pfam14450
550537000712	HMMPfam hit to PF02491, Cell division protein FtsA, score 7.6e-79
550537000713	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000714	HMMPfam hit to PF02491, Cell division protein FtsA, score 2.1e-79
550537000715	cell division protein FtsZ; Validated; Region: PRK09330
550537000716	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
550537000717	nucleotide binding site [chemical binding]; other site
550537000718	SulA interaction site; other site
550537000719	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
550537000720	HMMPfam hit to PF00091, Tubulin/FtsZ, GTPase, score 1.1e-93
550537000721	PS01134 FtsZ protein signature 1.
550537000722	PS01135 FtsZ protein signature 2.
550537000723	HMMPfam hit to PF03953, Tubulin/FtsZ, C-terminal, score 1.4e-43
550537000724	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
550537000725	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
550537000726	HMMPfam hit to PF03331, UDP-3-O-acyl N-acetylglucosamine deacetylase, score 4e-193
550537000727	SecA regulator SecM; Provisional; Region: PRK02943
550537000728	HMMPfam hit to PF06558, Secretion monitor, score 3.6e-105
550537000729	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
550537000730	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
550537000731	SEC-C motif; Region: SEC-C; pfam02810
550537000732	HMMPfam hit to PF07517, SecA DEAD-like, score 2.3e-218
550537000733	HMMPfam hit to PF01043, SecA preprotein cross-linking region, score 1.3e-83
550537000734	PS01312 Protein secA signatures.
550537000735	HMMPfam hit to PF07516, SecA Wing and Scaffold, score 3.2e-124
550537000736	HMMPfam hit to PF02810, SEC-C motif, score 2.8e-11
550537000737	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
550537000738	active site
550537000739	8-oxo-dGMP binding site [chemical binding]; other site
550537000740	nudix motif; other site
550537000741	metal binding site [ion binding]; metal-binding site
550537000742	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 1.5e-30
550537000743	PS00893 mutT domain signature.
550537000744	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537000745	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537000746	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
550537000747	putative effector binding pocket; other site
550537000748	putative dimerization interface [polypeptide binding]; other site
550537000749	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.7e-21
550537000750	PS00044 Bacterial regulatory proteins, lysR family signature.
550537000751	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.2e-39
550537000752	DNA gyrase inhibitor; Reviewed; Region: PRK00418
550537000753	HMMPfam hit to PF03884, Protein of unknown function DUF329, score 1.9e-36
550537000754	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
550537000755	HMMPfam hit to PF07072, Protein of unknown function DUF1342, score 1.5e-162
550537000756	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
550537000757	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
550537000758	CoA-binding site [chemical binding]; other site
550537000759	ATP-binding [chemical binding]; other site
550537000760	HMMPfam hit to PF01121, Dephospho-CoA kinase, score 4.3e-110
550537000761	PS01294 Uncharacterized protein family UPF0038 signature.
550537000762	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000763	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
550537000764	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
550537000765	active site
550537000766	HMMPfam hit to PF00478, IMP dehydrogenase/GMP reductase, score 4.2e-162
550537000767	PS00487 IMP dehydrogenase / GMP reductase signature.
550537000768	type IV pilin biogenesis protein; Provisional; Region: PRK10573
550537000769	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
550537000770	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
550537000771	3 probable transmembrane helices predicted for SEN0146 by TMHMM2.0 at aa 163-185, 205-227 and 368-390
550537000772	HMMPfam hit to PF00482, Bacterial type II secretion system protein, score 6e-17
550537000773	HMMPfam hit to PF00482, Bacterial type II secretion system protein, score 1e-19
550537000774	hypothetical protein; Provisional; Region: PRK10436
550537000775	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
550537000776	Walker A motif; other site
550537000777	ATP binding site [chemical binding]; other site
550537000778	Walker B motif; other site
550537000779	HMMPfam hit to PF00437, Bacterial type II secretion system protein E, score 3.1e-123
550537000780	PS00662 Bacterial type II secretion system protein E signature.
550537000781	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000782	HMMPfam hit to PF05157, General secretory system II, protein E, N-terminal, score 3.3e-05
550537000783	putative major pilin subunit; Provisional; Region: PRK10574
550537000784	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
550537000785	Pilin (bacterial filament); Region: Pilin; pfam00114
550537000786	1 probable transmembrane helix predicted for SEN0148 by TMHMM2.0 at aa 7-29
550537000787	HMMPfam hit to PF07963, Prepilin-type cleavage/methylation, N-terminal, score 1.9e-08
550537000788	PS00409 Prokaryotic N-terminal methylation site.
550537000789	nicotinate-nucleotide pyrophosphorylase; Region: nadC; TIGR00078
550537000790	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
550537000791	dimerization interface [polypeptide binding]; other site
550537000792	active site
550537000793	HMMPfam hit to PF01729, Quinolinate phosphoribosyl transferase, score 2.8e-94
550537000794	HMMPfam hit to PF02749, Quinolinate phosphoribosyl transferase, score 1.3e-32
550537000795	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
550537000796	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
550537000797	amidase catalytic site [active]
550537000798	Zn binding residues [ion binding]; other site
550537000799	substrate binding site [chemical binding]; other site
550537000800	HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, family 2, score 6.1e-65
550537000801	regulatory protein AmpE; Provisional; Region: PRK10987
550537000802	4 probable transmembrane helices predicted for SEN0151 by TMHMM2.0 at aa 36-58, 63-85, 146-168 and 266-283
550537000803	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
550537000804	active site
550537000805	HMMPfam hit to PF04616, Glycoside hydrolase, family 43, score 1.3e-133
550537000806	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
550537000807	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537000808	putative substrate translocation pore; other site
550537000809	12 probable transmembrane helices predicted for SEN0153 by TMHMM2.0 at aa 12-31, 35-57, 81-100, 115-137, 150-172, 182-204, 234-256, 266-288, 295-317, 322-344, 365-387 and 407-429
550537000810	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 6.2e-09
550537000811	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537000812	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000813	aromatic amino acid transporter; Provisional; Region: PRK10238
550537000814	HMMPfam hit to PF00324, Amino acid permease-associated region, score 1.1e-172
550537000815	12 probable transmembrane helices predicted for SEN0154 by TMHMM2.0 at aa 21-43, 47-66, 86-108, 118-140, 153-175, 198-220, 240-262, 282-304, 331-353, 357-379, 399-421 and 426-445
550537000816	PS00218 Amino acid permeases signature.
550537000817	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
550537000818	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537000819	DNA-binding site [nucleotide binding]; DNA binding site
550537000820	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
550537000821	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 3.9e-34
550537000822	PS00043 Bacterial regulatory proteins, gntR family signature.
550537000823	HMMPfam hit to PF07729, GntR, C-terminal, score 1.1e-30
550537000824	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
550537000825	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
550537000826	dimer interface [polypeptide binding]; other site
550537000827	TPP-binding site [chemical binding]; other site
550537000828	HMMPfam hit to PF00456, Transketolase, N-terminal, score 7e-05
550537000829	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
550537000830	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
550537000831	E3 interaction surface; other site
550537000832	lipoyl attachment site [posttranslational modification]; other site
550537000833	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
550537000834	E3 interaction surface; other site
550537000835	lipoyl attachment site [posttranslational modification]; other site
550537000836	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
550537000837	E3 interaction surface; other site
550537000838	lipoyl attachment site [posttranslational modification]; other site
550537000839	e3 binding domain; Region: E3_binding; pfam02817
550537000840	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
550537000841	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 5.4e-29
550537000842	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
550537000843	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 4.2e-29
550537000844	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
550537000845	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 5.4e-28
550537000846	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
550537000847	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000848	HMMPfam hit to PF02817, E3 binding, score 2e-18
550537000849	HMMPfam hit to PF00198, Catalytic domain of components of various dehydrogenase complexes, score 1.7e-110
550537000850	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
550537000851	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
550537000852	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537000853	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
550537000854	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 1.1e-76
550537000855	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
550537000856	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 1.3e-24
550537000857	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase dimerisation region, score 2.5e-52
550537000858	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
550537000859	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
550537000860	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
550537000861	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
550537000862	substrate binding site [chemical binding]; other site
550537000863	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
550537000864	substrate binding site [chemical binding]; other site
550537000865	ligand binding site [chemical binding]; other site
550537000866	HMMPfam hit to PF06434, Aconitase B, N-terminal, bacterial, score 4.3e-291
550537000867	HMMPfam hit to PF00330, Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, score 5.4e-11
550537000868	PS00450 Aconitase family signature 1.
550537000869	PS01244 Aconitase family signature 2.
550537000870	putative inner membrane protein; Provisional; Region: PRK09823
550537000871	4 probable transmembrane helices predicted for SEN0163 by TMHMM2.0 at aa 13-35, 55-77, 90-109 and 124-146
550537000872	Low molecular weight phosphatase family; Region: LMWPc; cl00105
550537000873	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
550537000874	active site
550537000875	hypothetical protein; Provisional; Region: PRK05248
550537000876	HMMPfam hit to PF06062, Uncharacterised conserved protein UCP006287, score 3e-72
550537000877	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
550537000878	HMMPfam hit to PF03812, 2-keto-3-deoxygluconate permease, score 5.2e-95
550537000879	10 probable transmembrane helices predicted for SEN0166 by TMHMM2.0 at aa 13-35, 45-64, 71-90, 100-122, 134-156, 160-182, 189-211, 215-237, 244-266 and 281-303
550537000880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
550537000881	HMMPfam hit to PF07005, Type III effector Hrp-dependent outers, score 2.1e-05
550537000882	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
550537000883	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
550537000884	HMMPfam hit to PF04166, Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA, score 6.1e-117
550537000885	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000886	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537000887	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537000888	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537000889	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 7.2e-19
550537000890	PS00894 Bacterial regulatory proteins, deoR family signature.
550537000891	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 1.8e-45
550537000892	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000893	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
550537000894	HMMPfam hit to PF02675, S-adenosylmethionine decarboxylase related, score 1.3e-78
550537000895	spermidine synthase; Provisional; Region: PRK00811
550537000896	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537000897	S-adenosylmethionine binding site [chemical binding]; other site
550537000898	HMMPfam hit to PF01564, Spermine synthase, score 4.4e-134
550537000899	PS00136 Serine proteases, subtilase family, aspartic acid active site.
550537000900	PS01330 Spermidine/spermine synthases family signature.
550537000901	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
550537000902	multicopper oxidase; Provisional; Region: PRK10965
550537000903	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
550537000904	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
550537000905	HMMPfam hit to PF07732, Multicopper oxidase, type 3, score 1.4e-42
550537000906	HMMPfam hit to PF07731, Multicopper oxidase, type 2, score 2.2e-17
550537000907	PS00080 Multicopper oxidases signature 2.
550537000908	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
550537000909	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
550537000910	Trp docking motif [polypeptide binding]; other site
550537000911	putative active site [active]
550537000912	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 1e-07
550537000913	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 3e-06
550537000914	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 0.00079
550537000915	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 9.8e-05
550537000916	PS00364 Bacterial quinoprotein dehydrogenases signature 2.
550537000917	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 0.00044
550537000918	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 4.1e-05
550537000919	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 5.2e-10
550537000920	5 probable transmembrane helices predicted for SEN0174 by TMHMM2.0 at aa 13-35, 40-57, 64-81, 96-114 and 121-140
550537000921	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
550537000922	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537000923	active site
550537000924	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 4.7e-39
550537000925	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
550537000926	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
550537000927	active site clefts [active]
550537000928	zinc binding site [ion binding]; other site
550537000929	dimer interface [polypeptide binding]; other site
550537000930	HMMPfam hit to PF00484, Carbonic anhydrase, score 1.5e-63
550537000931	PS00705 Prokaryotic-type carbonic anhydrases signature 2.
550537000932	PS00704 Prokaryotic-type carbonic anhydrases signature 1.
550537000933	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
550537000934	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
550537000935	Walker A/P-loop; other site
550537000936	ATP binding site [chemical binding]; other site
550537000937	Q-loop/lid; other site
550537000938	ABC transporter signature motif; other site
550537000939	Walker B; other site
550537000940	D-loop; other site
550537000941	H-loop/switch region; other site
550537000942	HMMPfam hit to PF00005, ABC transporter related, score 1.2e-52
550537000943	PS00017 ATP/GTP-binding site motif A (P-loop).
550537000944	PS00211 ABC transporters family signature.
550537000945	inner membrane transport permease; Provisional; Region: PRK15066
550537000946	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
550537000947	HMMPfam hit to PF01061, ABC-2 type transporter, score 1.5e-48
550537000948	6 probable transmembrane helices predicted for SEN0178 by TMHMM2.0 at aa 20-42, 62-84, 104-126, 141-163, 170-192 and 226-248
550537000949	PS00890 ABC-2 type transport system integral membrane proteins signature.
550537000950	fimbrial operon sti
550537000951	putative fimbrial protein StiH; Provisional; Region: PRK15297
550537000952	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.0015
550537000953	fimbrial outer membrane usher protein StiC; Provisional; Region: PRK15298
550537000954	PapC N-terminal domain; Region: PapC_N; pfam13954
550537000955	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537000956	PapC C-terminal domain; Region: PapC_C; pfam13953
550537000957	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537000958	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537000959	1 probable transmembrane helix predicted for SEN0180 by TMHMM2.0 at aa 7-29
550537000960	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
550537000961	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537000962	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537000963	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 5e-23
550537000964	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 2.1e-45
550537000965	fimbrial protein StiA; Provisional; Region: PRK15300
550537000966	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 2e-31
550537000967	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
550537000968	active pocket/dimerization site; other site
550537000969	active site
550537000970	phosphorylation site [posttranslational modification]
550537000971	HMMPfam hit to PF03610, Phosphotransferase system, fructose subfamily IIA component, score 4.8e-30
550537000972	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
550537000973	putative active site [active]
550537000974	putative metal binding site [ion binding]; other site
550537000975	1 probable transmembrane helix predicted for SEN0184 by TMHMM2.0 at aa 5-27
550537000976	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 6e-29
550537000977	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
550537000978	tetramerization interface [polypeptide binding]; other site
550537000979	active site
550537000980	HMMPfam hit to PF02261, Aspartate decarboxylase, score 2.6e-84
550537000981	PS00678 Trp-Asp (WD) repeats signature.
550537000982	Pantoate-beta-alanine ligase; Region: PanC; cd00560
550537000983	pantoate--beta-alanine ligase; Region: panC; TIGR00018
550537000984	active site
550537000985	ATP-binding site [chemical binding]; other site
550537000986	pantoate-binding site; other site
550537000987	HXXH motif; other site
550537000988	HMMPfam hit to PF02569, Pantoate-beta-alanine ligase, score 2.4e-169
550537000989	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
550537000990	oligomerization interface [polypeptide binding]; other site
550537000991	active site
550537000992	metal binding site [ion binding]; metal-binding site
550537000993	HMMPfam hit to PF02548, Ketopantoate hydroxymethyltransferase, score 4.6e-170
550537000994	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
550537000995	catalytic center binding site [active]
550537000996	ATP binding site [chemical binding]; other site
550537000997	HMMPfam hit to PF01288, 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK, score 1.2e-74
550537000998	PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature.
550537000999	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
550537001000	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
550537001001	active site
550537001002	NTP binding site [chemical binding]; other site
550537001003	metal binding triad [ion binding]; metal-binding site
550537001004	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
550537001005	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
550537001006	HMMPfam hit to PF01743, Polynucleotide adenylyltransferase region, score 6.3e-74
550537001007	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
550537001008	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
550537001009	active site
550537001010	nucleotide binding site [chemical binding]; other site
550537001011	HIGH motif; other site
550537001012	KMSKS motif; other site
550537001013	HMMPfam hit to PF00749, Glutamyl/glutaminyl-tRNA synthetase, class Ic, score 4e-30
550537001014	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
550537001015	HMMPfam hit to PF01258, Zinc finger, DksA/TraR C4-type, score 3.4e-36
550537001016	PS01102 Prokaryotic dksA/traR C4-type zinc finger.
550537001017	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
550537001018	HMMPfam hit to PF03749, Sugar fermentation stimulation protein, score 1.6e-104
550537001019	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001020	2'-5' RNA ligase; Provisional; Region: PRK15124
550537001021	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
550537001022	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
550537001023	HMMPfam hit to PF02834, Phosphoesterase, HXTX, score 7.5e-09
550537001024	HMMPfam hit to PF02834, Phosphoesterase, HXTX, score 1.5e-19
550537001025	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
550537001026	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537001027	ATP binding site [chemical binding]; other site
550537001028	putative Mg++ binding site [ion binding]; other site
550537001029	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537001030	nucleotide binding region [chemical binding]; other site
550537001031	ATP-binding site [chemical binding]; other site
550537001032	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
550537001033	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 4.7e-07
550537001034	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001035	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 8.5e-11
550537001036	HMMPfam hit to PF04408, Helicase-associated region, score 8.7e-08
550537001037	PS00177 DNA topoisomerase II signature.
550537001038	HMMPfam hit to PF08482, RNA helicase, ATP-dependent, HrpB type, C-terminal, score 3e-94
550537001039	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
550537001040	Transglycosylase; Region: Transgly; pfam00912
550537001041	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
550537001042	1 probable transmembrane helix predicted for SEN0195 by TMHMM2.0 at aa 60-82
550537001043	HMMPfam hit to PF00912, Glycosyl transferase, family 51, score 1.6e-83
550537001044	HMMPfam hit to PF00905, Penicillin-binding protein, transpeptidase, score 4.8e-20
550537001045	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001046	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
550537001047	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537001048	N-terminal plug; other site
550537001049	ligand-binding site [chemical binding]; other site
550537001050	PS00430 TonB-dependent receptor proteins signature 1.
550537001051	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 2.2e-21
550537001052	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 8e-26
550537001053	PS01156 TonB-dependent receptor proteins signature 2.
550537001054	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
550537001055	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
550537001056	Walker A/P-loop; other site
550537001057	ATP binding site [chemical binding]; other site
550537001058	Q-loop/lid; other site
550537001059	ABC transporter signature motif; other site
550537001060	Walker B; other site
550537001061	D-loop; other site
550537001062	H-loop/switch region; other site
550537001063	HMMPfam hit to PF00005, ABC transporter related, score 5.5e-58
550537001064	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001065	PS00211 ABC transporters family signature.
550537001066	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
550537001067	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
550537001068	siderophore binding site; other site
550537001069	PS00228 Tubulin-beta mRNA autoregulation signal.
550537001070	HMMPfam hit to PF01497, Periplasmic binding protein, score 7.2e-08
550537001071	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537001072	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
550537001073	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537001074	ABC-ATPase subunit  interface; other site
550537001075	dimer interface [polypeptide binding]; other site
550537001076	putative PBP binding regions; other site
550537001077	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537001078	ABC-ATPase subunit  interface; other site
550537001079	dimer interface [polypeptide binding]; other site
550537001080	putative PBP binding regions; other site
550537001081	17 probable transmembrane helices predicted for SEN0199 by TMHMM2.0 at aa 35-57, 82-104, 117-136, 140-162, 169-191, 264-286, 298-316, 326-348, 372-394, 414-436, 449-467, 471-493, 505-524, 544-566, 593-615, 630-649 and 656-678
550537001082	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001083	HMMPfam hit to PF01032, Bacterial transport system permease protein, score 1.5e-37
550537001084	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001085	HMMPfam hit to PF01032, Bacterial transport system permease protein, score 2.6e-61
550537001086	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001087	fimbrial operon stf
550537001088	putative fimbrial subunit StfA; Provisional; Region: PRK15283
550537001089	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 4.2e-28
550537001090	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
550537001091	PapC N-terminal domain; Region: PapC_N; pfam13954
550537001092	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537001093	PapC C-terminal domain; Region: PapC_C; pfam13953
550537001094	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537001095	PS00489 Bacteriophage-type RNA polymerase family active site signature 2.
550537001096	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537001097	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
550537001098	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537001099	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537001100	1 probable transmembrane helix predicted for SEN0202 by TMHMM2.0 at aa 7-29
550537001101	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 1.9e-39
550537001102	PS00635 Gram-negative pili assembly chaperone signature.
550537001103	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 0.00021
550537001104	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
550537001105	putative minor fimbrial subunit StfF; Provisional; Region: PRK15287
550537001106	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.00061
550537001107	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
550537001108	1 probable transmembrane helix predicted for SEN0205 by TMHMM2.0 at aa 7-26
550537001109	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 1.8e-14
550537001110	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
550537001111	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
550537001112	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
550537001113	inhibitor-cofactor binding pocket; inhibition site
550537001114	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537001115	catalytic residue [active]
550537001116	HMMPfam hit to PF00202, Aminotransferase class-III, score 3.3e-93
550537001117	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001118	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
550537001119	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
550537001120	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
550537001121	Cl- selectivity filter; other site
550537001122	Cl- binding residues [ion binding]; other site
550537001123	pore gating glutamate residue; other site
550537001124	dimer interface [polypeptide binding]; other site
550537001125	H+/Cl- coupling transport residue; other site
550537001126	11 probable transmembrane helices predicted for SEN0208 by TMHMM2.0 at aa 31-53, 75-97, 124-146, 179-201, 210-232, 252-274, 291-310, 320-342, 355-377, 390-412 and 419-441
550537001127	HMMPfam hit to PF00654, Chloride channel, core, score 1.7e-119
550537001128	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001129	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
550537001130	HMMPfam hit to PF01521, HesB/YadR/YfhF, score 1e-42
550537001131	PS01152 Hypothetical hesB/yadR/yfhF family signature.
550537001132	hypothetical protein; Provisional; Region: PRK10578
550537001133	UPF0126 domain; Region: UPF0126; pfam03458
550537001134	UPF0126 domain; Region: UPF0126; pfam03458
550537001135	HMMPfam hit to PF03458, Protein of unknown function UPF0126, score 1.6e-32
550537001136	6 probable transmembrane helices predicted for SEN0210 by TMHMM2.0 at aa 4-23, 30-47, 62-79, 88-105, 115-137 and 149-171
550537001137	HMMPfam hit to PF03458, Protein of unknown function UPF0126, score 1e-38
550537001138	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
550537001139	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
550537001140	cobalamin binding residues [chemical binding]; other site
550537001141	putative BtuC binding residues; other site
550537001142	dimer interface [polypeptide binding]; other site
550537001143	HMMPfam hit to PF01497, Periplasmic binding protein, score 9.6e-51
550537001144	1 probable transmembrane helix predicted for SEN0211 by TMHMM2.0 at aa 7-29
550537001145	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
550537001146	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
550537001147	HMMPfam hit to PF01048, Nucleoside phosphorylase, score 1.2e-109
550537001148	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
550537001149	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
550537001150	Zn2+ binding site [ion binding]; other site
550537001151	Mg2+ binding site [ion binding]; other site
550537001152	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
550537001153	HMMPfam hit to PF01966, Metal-dependent phosphohydrolase, HD region, subdomain, score 5.6e-07
550537001154	serine endoprotease; Provisional; Region: PRK10942
550537001155	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
550537001156	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
550537001157	protein binding site [polypeptide binding]; other site
550537001158	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
550537001159	HMMPfam hit to PF00089, Peptidase S1 and S6, chymotrypsin/Hap, score 1.8e-35
550537001160	HMMPfam hit to PF00595, PDZ/DHR/GLGF, score 1.5e-21
550537001161	HMMPfam hit to PF00595, PDZ/DHR/GLGF, score 2.9e-19
550537001162	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
550537001163	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
550537001164	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
550537001165	HMMPfam hit to PF05651,  sugar diacid recognition, score 2.6e-170
550537001166	Viral enhancin protein; Region: Enhancin; pfam03272
550537001167	Peptidase M60-like family; Region: M60-like; pfam13402
550537001168	HMMPfam hit to PF03272, Peptidase M60, viral enhancin protein, score 2.6e-07
550537001169	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537001170	hypothetical protein; Provisional; Region: PRK13677
550537001171	shikimate transporter; Provisional; Region: PRK09952
550537001172	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537001173	putative substrate translocation pore; other site
550537001174	11 probable transmembrane helices predicted for SEN0218 by TMHMM2.0 at aa 27-46, 51-73, 85-107, 122-144, 151-173, 183-202, 244-266, 276-298, 310-329, 374-396 and 403-425
550537001175	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.3e-12
550537001176	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
550537001177	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
550537001178	trimer interface [polypeptide binding]; other site
550537001179	active site
550537001180	substrate binding site [chemical binding]; other site
550537001181	CoA binding site [chemical binding]; other site
550537001182	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1.9
550537001183	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 8.8
550537001184	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.82
550537001185	PS00101 Hexapeptide-repeat containing-transferases signature.
550537001186	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 30
550537001187	PII uridylyl-transferase; Provisional; Region: PRK05007
550537001188	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
550537001189	metal binding triad; other site
550537001190	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
550537001191	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
550537001192	Zn2+ binding site [ion binding]; other site
550537001193	Mg2+ binding site [ion binding]; other site
550537001194	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
550537001195	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
550537001196	HMMPfam hit to PF01842, Amino acid-binding ACT, score 1.7e-07
550537001197	HMMPfam hit to PF01842, Amino acid-binding ACT, score 3.2e-07
550537001198	HMMPfam hit to PF01966, Metal-dependent phosphohydrolase, HD region, subdomain, score 4.8e-21
550537001199	HMMPfam hit to PF08335, GlnD PII-uridylyltransferase, score 1.6e-116
550537001200	HMMPfam hit to PF01909, DNA polymerase, beta-like region, score 3.6e-13
550537001201	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
550537001202	active site
550537001203	HMMPfam hit to PF00557, Peptidase M24, catalytic core, score 2.8e-105
550537001204	PS00680 Methionine aminopeptidase subfamily 1 signature.
550537001205	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
550537001206	rRNA interaction site [nucleotide binding]; other site
550537001207	S8 interaction site; other site
550537001208	putative laminin-1 binding site; other site
550537001209	PS00962 Ribosomal protein S2 signature 1.
550537001210	HMMPfam hit to PF00318, Ribosomal protein S2, score 5.7e-130
550537001211	PS00963 Ribosomal protein S2 signature 2.
550537001212	elongation factor Ts; Provisional; Region: tsf; PRK09377
550537001213	UBA/TS-N domain; Region: UBA; pfam00627
550537001214	Elongation factor TS; Region: EF_TS; pfam00889
550537001215	Elongation factor TS; Region: EF_TS; pfam00889
550537001216	HMMPfam hit to PF00627, Ubiquitin-associated_translation elongation factor EF1B, N-terminal, score 6.2e-13
550537001217	PS01126 Elongation factor Ts signature 1.
550537001218	HMMPfam hit to PF00889, Translation elongation factor EFTs/EF1B, dimerisation, score 4.6e-108
550537001219	PS01127 Elongation factor Ts signature 2.
550537001220	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
550537001221	putative nucleotide binding site [chemical binding]; other site
550537001222	uridine monophosphate binding site [chemical binding]; other site
550537001223	homohexameric interface [polypeptide binding]; other site
550537001224	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 1.4e-63
550537001225	ribosome recycling factor; Reviewed; Region: frr; PRK00083
550537001226	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
550537001227	hinge region; other site
550537001228	HMMPfam hit to PF01765, Ribosome recycling factor, score 3.1e-101
550537001229	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
550537001230	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
550537001231	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
550537001232	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
550537001233	HMMPfam hit to PF02670, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal, score 2.2e-80
550537001234	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001235	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001236	HMMPfam hit to PF08436, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal, score 1.7e-60
550537001237	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
550537001238	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
550537001239	catalytic residue [active]
550537001240	putative FPP diphosphate  binding site; other site
550537001241	putative FPP binding hydrophobic cleft; other site
550537001242	dimer interface [polypeptide binding]; other site
550537001243	putative IPP diphosphate binding site; other site
550537001244	HMMPfam hit to PF01255, Di-trans-poly-cis-decaprenylcistransferase, score 2.9e-149
550537001245	PS01066 Undecaprenyl pyrophosphate synthetase family signature.
550537001246	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
550537001247	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
550537001248	HMMPfam hit to PF01148, Phosphatidate cytidylyltransferase, score 3.7e-85
550537001249	8 probable transmembrane helices predicted for SEN0229 by TMHMM2.0 at aa 7-41, 56-74, 87-106, 121-143, 150-172, 192-211, 218-240 and 260-282
550537001250	PS01315 Phosphatidate cytidylyltransferase signature.
550537001251	zinc metallopeptidase RseP; Provisional; Region: PRK10779
550537001252	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
550537001253	active site
550537001254	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
550537001255	protein binding site [polypeptide binding]; other site
550537001256	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
550537001257	protein binding site [polypeptide binding]; other site
550537001258	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
550537001259	putative substrate binding region [chemical binding]; other site
550537001260	4 probable transmembrane helices predicted for SEN0230 by TMHMM2.0 at aa 2-21, 98-120, 376-398 and 426-445
550537001261	HMMPfam hit to PF02163, Peptidase M50, score 7.5e-95
550537001262	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537001263	HMMPfam hit to PF00595, PDZ/DHR/GLGF, score 4.8e-13
550537001264	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
550537001265	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
550537001266	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
550537001267	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
550537001268	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
550537001269	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
550537001270	Surface antigen; Region: Bac_surface_Ag; pfam01103
550537001271	HMMPfam hit to PF07244, Surface antigen variable number, score 1.1e-11
550537001272	HMMPfam hit to PF07244, Surface antigen variable number, score 3.1e-16
550537001273	HMMPfam hit to PF07244, Surface antigen variable number, score 1.2e-18
550537001274	HMMPfam hit to PF07244, Surface antigen variable number, score 2.6e-16
550537001275	HMMPfam hit to PF07244, Surface antigen variable number, score 4.1e-21
550537001276	HMMPfam hit to PF01103, Bacterial surface antigen (D15), score 2.9e-77
550537001277	periplasmic chaperone; Provisional; Region: PRK10780
550537001278	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
550537001279	HMMPfam hit to PF03938, Outer membrane chaperone Skp (OmpH), score 3.3e-36
550537001280	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
550537001281	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
550537001282	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
550537001283	trimer interface [polypeptide binding]; other site
550537001284	active site
550537001285	UDP-GlcNAc binding site [chemical binding]; other site
550537001286	lipid binding site [chemical binding]; lipid-binding site
550537001287	HMMPfam hit to PF04613, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD, score 1.7e-32
550537001288	PS00101 Hexapeptide-repeat containing-transferases signature.
550537001289	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.37
550537001290	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.011
550537001291	PS00101 Hexapeptide-repeat containing-transferases signature.
550537001292	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.033
550537001293	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.14
550537001294	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.3
550537001295	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.021
550537001296	PS00101 Hexapeptide-repeat containing-transferases signature.
550537001297	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1
550537001298	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 16
550537001299	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
550537001300	HMMPfam hit to PF07977, Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ, score 8.1e-67
550537001301	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
550537001302	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
550537001303	active site
550537001304	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.0012
550537001305	PS00101 Hexapeptide-repeat containing-transferases signature.
550537001306	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1.5
550537001307	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 3.4
550537001308	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 7.5
550537001309	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 85
550537001310	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.67
550537001311	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1.2
550537001312	PS00101 Hexapeptide-repeat containing-transferases signature.
550537001313	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001314	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
550537001315	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
550537001316	HMMPfam hit to PF02684, Glycosyl transferase, family 19, score 1.7e-219
550537001317	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
550537001318	RNA/DNA hybrid binding site [nucleotide binding]; other site
550537001319	active site
550537001320	HMMPfam hit to PF01351, Ribonuclease HII/HIII, score 2.5e-94
550537001321	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
550537001322	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
550537001323	putative active site [active]
550537001324	putative PHP Thumb interface [polypeptide binding]; other site
550537001325	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
550537001326	generic binding surface II; other site
550537001327	generic binding surface I; other site
550537001328	HMMPfam hit to PF02811, PHP, C-terminal, score 1.5e-60
550537001329	HMMPfam hit to PF07733, Bacterial DNA polymerase III, alpha subunit, score 0
550537001330	HMMPfam hit to PF01336, Nucleic acid binding, OB-fold, tRNA/helicase-type, score 7.9e-13
550537001331	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
550537001332	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
550537001333	HMMPfam hit to PF03255, Acetyl-CoA carboxylase, alpha subunit, score 6.4e-102
550537001334	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
550537001335	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
550537001336	putative sugar binding site [chemical binding]; other site
550537001337	catalytic residues [active]
550537001338	PKD domain; Region: PKD; pfam00801
550537001339	1 probable transmembrane helix predicted for SEN0240 by TMHMM2.0 at aa 7-29
550537001340	HMMPfam hit to PF00182, Glycoside hydrolase, family 19, catalytic, score 2.2e-29
550537001341	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001342	HMMPfam hit to PF00801, PKD, score 5.3e-08
550537001343	HMMPfam hit to PF02839, Carbohydrate-binding family V/XII, score 0.042
550537001344	lysine decarboxylase LdcC; Provisional; Region: PRK15399
550537001345	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
550537001346	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
550537001347	homodimer interface [polypeptide binding]; other site
550537001348	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537001349	catalytic residue [active]
550537001350	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
550537001351	HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal, score 1.5e-39
550537001352	HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major region, score 7.8e-287
550537001353	PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site.
550537001354	HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal, score 1e-85
550537001355	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
550537001356	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
550537001357	putative metal binding site [ion binding]; other site
550537001358	HMMPfam hit to PF00903, Glyoxalase/bleomycin resistance protein/dioxygenase, score 1.3e-30
550537001359	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
550537001360	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
550537001361	TilS substrate binding domain; Region: TilS; pfam09179
550537001362	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
550537001363	HMMPfam hit to PF01171, PP-loop, score 2e-72
550537001364	HMMPfam hit to PF09179, Protein of unkown function DUF1946, PP-loop ATpase, score 6.2e-94
550537001365	Rho-binding antiterminator; Provisional; Region: PRK11625
550537001366	HMMPfam hit to PF07073, Modulator of Rho-dependent transcription termination, score 9.9e-45
550537001367	hypothetical protein; Provisional; Region: PRK04964
550537001368	HMMPfam hit to PF06786, Protein of unknown function UPF0253, score 7e-42
550537001369	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
550537001370	HMMPfam hit to PF07152, YaeQ, score 1.2e-128
550537001371	hypothetical protein; Provisional; Region: PRK09256
550537001372	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
550537001373	HMMPfam hit to PF00472, Class I peptide chain release factor, score 4.5e-37
550537001374	PS00745 Prokaryotic-type class I peptide chain release factors signature.
550537001375	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
550537001376	NlpE N-terminal domain; Region: NlpE; pfam04170
550537001377	HMMPfam hit to PF04170, Copper resistance lipoprotein NlpE, score 2.1e-115
550537001378	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001379	PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature.
550537001380	prolyl-tRNA synthetase; Provisional; Region: PRK09194
550537001381	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
550537001382	dimer interface [polypeptide binding]; other site
550537001383	motif 1; other site
550537001384	active site
550537001385	motif 2; other site
550537001386	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
550537001387	putative deacylase active site [active]
550537001388	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
550537001389	active site
550537001390	motif 3; other site
550537001391	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
550537001392	anticodon binding site; other site
550537001393	HMMPfam hit to PF03129, Anticodon-binding, score 1e-26
550537001394	HMMPfam hit to PF04073, YbaK/prolyl-tRNA synthetase associated region, score 9.8e-08
550537001395	HMMPfam hit to PF00587, Aminoacyl-tRNA synthetase, class II (G, H, P and S), score 1.3e-66
550537001396	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537001397	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
550537001398	homodimer interaction site [polypeptide binding]; other site
550537001399	cofactor binding site; other site
550537001400	HMMPfam hit to PF01980, Protein of unknown function UPF0066, score 2.1e-54
550537001401	PS01318 Uncharacterized protein family UPF0066 signature.
550537001402	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
550537001403	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001404	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
550537001405	lipoprotein, YaeC family; Region: TIGR00363
550537001406	HMMPfam hit to PF03180, NLPA lipoprotein, score 3.2e-151
550537001407	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001408	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537001409	dimer interface [polypeptide binding]; other site
550537001410	conserved gate region; other site
550537001411	ABC-ATPase subunit interface; other site
550537001412	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.1e-21
550537001413	5 probable transmembrane helices predicted for SEN0254 by TMHMM2.0 at aa 20-42, 55-77, 81-103, 144-166 and 181-203
550537001414	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537001415	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
550537001416	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
550537001417	Walker A/P-loop; other site
550537001418	ATP binding site [chemical binding]; other site
550537001419	Q-loop/lid; other site
550537001420	ABC transporter signature motif; other site
550537001421	Walker B; other site
550537001422	D-loop; other site
550537001423	H-loop/switch region; other site
550537001424	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
550537001425	HMMPfam hit to PF00005, ABC transporter related, score 3.1e-75
550537001426	PS00211 ABC transporters family signature.
550537001427	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001428	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
550537001429	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537001430	active site
550537001431	motif I; other site
550537001432	motif II; other site
550537001433	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.2e-08
550537001434	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537001435	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537001436	active site
550537001437	catalytic tetrad [active]
550537001438	HMMPfam hit to PF00248, Aldo/keto reductase, score 2.6e-86
550537001439	PS00798 Aldo/keto reductase family signature 1.
550537001440	PS00062 Aldo/keto reductase family signature 2.
550537001441	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537001442	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537001443	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
550537001444	putative effector binding pocket; other site
550537001445	dimerization interface [polypeptide binding]; other site
550537001446	HMMPfam hit to PF03466, LysR, substrate-binding, score 2e-49
550537001447	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2.9e-20
550537001448	PS00044 Bacterial regulatory proteins, lysR family signature.
550537001449	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
550537001450	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537001451	putative substrate translocation pore; other site
550537001452	12 probable transmembrane helices predicted for SEN0259 by TMHMM2.0 at aa 7-29, 39-61, 70-89, 99-121, 128-150, 160-182, 202-224, 234-256, 263-285, 289-311, 332-354 and 358-380
550537001453	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.5e-44
550537001454	hypothetical protein; Provisional; Region: PRK05421
550537001455	putative catalytic site [active]
550537001456	putative metal binding site [ion binding]; other site
550537001457	putative phosphate binding site [ion binding]; other site
550537001458	putative catalytic site [active]
550537001459	putative phosphate binding site [ion binding]; other site
550537001460	putative metal binding site [ion binding]; other site
550537001461	HMMPfam hit to PF03372, Endonuclease/exonuclease/phosphatase, score 1.2e-22
550537001462	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537001463	S-adenosylmethionine binding site [chemical binding]; other site
550537001464	HMMPfam hit to PF08241, Methyltransferase type 11, score 3.2e-35
550537001465	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
550537001466	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
550537001467	N-acetyl-D-glucosamine binding site [chemical binding]; other site
550537001468	catalytic residue [active]
550537001469	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537001470	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537001471	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 2.5e-13
550537001472	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 3.3e-17
550537001473	HMMPfam hit to PF01464, Lytic transglycosylase-like, catalytic, score 6.7e-38
550537001474	PS00922 Prokaryotic transglycosylases signature.
550537001475	HMMPfam hit to PF06474, MLTD-N, score 4.1e-40
550537001476	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001477	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
550537001478	HMMPfam hit to PF00753, Beta-lactamase-like, score 7.6e-38
550537001479	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537001480	HMMPfam hit to PF08241, Methyltransferase type 11, score 4.9e-09
550537001481	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
550537001482	RNA/DNA hybrid binding site [nucleotide binding]; other site
550537001483	active site
550537001484	HMMPfam hit to PF00075, Ribonuclease H, score 1.9e-72
550537001485	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
550537001486	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
550537001487	active site
550537001488	catalytic site [active]
550537001489	substrate binding site [chemical binding]; other site
550537001490	HMMPfam hit to PF00929, Exonuclease, RNase T and DNA polymerase III, score 3.5e-52
550537001491	Salmonella Pathogenicity Island 6: SPI-6 degenerate
550537001492	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
550537001493	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
550537001494	HMMPfam hit to PF06812, ImpA, N-terminal, score 9.6e-23
550537001496	HMMPfam hit to PF06996, Protein of unknown function DUF1305, score 2.2e-97
550537001498	A deletion event appears to have removed much of the 3' end of this CDS.
550537001499	A deletion event appears to have removed much of the 5' end of this CDS.
550537001500	HMMPfam hit to PF05593, YD repeat, score 2.6
550537001501	HMMPfam hit to PF05593, YD repeat, score 0.024
550537001502	HMMPfam hit to PF05593, YD repeat, score 0.00015
550537001503	HMMPfam hit to PF05593, YD repeat, score 0.00025
550537001504	HMMPfam hit to PF05593, YD repeat, score 2.5e-07
550537001505	HMMPfam hit to PF05593, YD repeat, score 0.0044
550537001506	HMMPfam hit to PF05593, YD repeat, score 0.0014
550537001507	HMMPfam hit to PF05593, YD repeat, score 1.7e-06
550537001508	HMMPfam hit to PF05593, YD repeat, score 2.5e-05
550537001509	HMMPfam hit to PF05593, YD repeat, score 0.00015
550537001510	HMMPfam hit to PF05593, YD repeat, score 0.0011
550537001511	HMMPfam hit to PF05593, YD repeat, score 0.031
550537001512	HMMPfam hit to PF05593, YD repeat, score 6.2e-06
550537001513	HMMPfam hit to PF03527, RHS protein, score 4.4e-22
550537001514	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
550537001515	HMMPfam hit to PF08845, Protein of unknown function DUF1813, HSP20-like, score 2.1e-15
550537001517	Protein of unknown function (DUF4019); Region: DUF4019; pfam13211
550537001518	1 probable transmembrane helix predicted for SEN0277 by TMHMM2.0 at aa 7-29
550537001519	note the frameshift mutation following codon 30
550537001520	HMMPfam hit to PF01527, Transposase IS3/IS911, score 1.9e-07
550537001521	Note the multiple frameshift mutations and premature stop codon.
550537001522	HMMPfam hit to PF00665, Integrase, catalytic core, score 6.1e-14
550537001523	Saf-pilin pilus formation protein SafA; Provisional; Region: PRK15221
550537001524	fimbrial operon saf
550537001525	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001526	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
550537001527	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537001528	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537001529	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 8.1e-58
550537001530	PS00635 Gram-negative pili assembly chaperone signature.
550537001531	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 4.9e-24
550537001532	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
550537001533	PapC N-terminal domain; Region: PapC_N; pfam13954
550537001534	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537001535	PapC C-terminal domain; Region: PapC_C; pfam13953
550537001536	1 probable transmembrane helix predicted for SEN0283 by TMHMM2.0 at aa 7-26
550537001537	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537001538	putative pilin structural protein SafD; Provisional; Region: PRK15222
550537001539	HMMPfam hit to PF05775, Enterobacteria AfaD invasin, score 3.7e-87
550537001540	1 probable transmembrane helix predicted for SEN0284 by TMHMM2.0 at aa 12-31
550537001541	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
550537001542	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
550537001543	putative active site [active]
550537001544	putative metal binding site [ion binding]; other site
550537001545	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 3.6e-30
550537001547	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537001548	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537001549	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537001550	dimerization interface [polypeptide binding]; other site
550537001551	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2.1e-15
550537001552	PS00044 Bacterial regulatory proteins, lysR family signature.
550537001553	HMMPfam hit to PF03466, LysR, substrate-binding, score 8e-19
550537001554	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
550537001555	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
550537001556	dimer interface [polypeptide binding]; other site
550537001557	HMMPfam hit to PF07813, Region of unknown function, Spy-related, score 0.0018
550537001558	HMMPfam hit to PF07813, Region of unknown function, Spy-related, score 0.0022
550537001559	C-N hydrolase family amidase; Provisional; Region: PRK10438
550537001560	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
550537001561	putative active site [active]
550537001562	catalytic triad [active]
550537001563	dimer interface [polypeptide binding]; other site
550537001564	multimer interface [polypeptide binding]; other site
550537001565	HMMPfam hit to PF00795, Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, score 1.3e-07
550537001566	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
550537001567	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
550537001568	active site
550537001569	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
550537001570	HMMPfam hit to PF09317, Protein of unknown function DUF1974, score 1.8e-185
550537001571	HMMPfam hit to PF00441, Acyl-CoA oxidase/dehydrogenase, type 1, score 1.9e-08
550537001572	HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal, score 7.8e-06
550537001573	2 probable transmembrane helices predicted for SEN0292 by TMHMM2.0 at aa 10-32 and 39-61
550537001574	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
550537001575	dimer interface [polypeptide binding]; other site
550537001576	active site
550537001577	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 4.8e-06
550537001578	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
550537001579	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
550537001580	putative active site [active]
550537001581	putative dimer interface [polypeptide binding]; other site
550537001582	HMMPfam hit to PF00310, Glutamine amidotransferase, class-II, score 6.4e-39
550537001583	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
550537001584	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
550537001585	HMMPfam hit to PF06104, Protein of unknown function DUF949, bacterial, score 2e-146
550537001586	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001587	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
550537001588	active site
550537001589	DNA polymerase IV; Validated; Region: PRK02406
550537001590	DNA binding site [nucleotide binding]
550537001591	HMMPfam hit to PF00817, UMUC-like DNA-repair protein, score 3.2e-135
550537001592	hypothetical protein; Reviewed; Region: PRK09588
550537001593	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
550537001594	HMMPfam hit to PF01139, Protein of unknown function UPF0027, score 4.2e-114
550537001595	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
550537001596	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
550537001597	HMMPfam hit to PF00472, Class I peptide chain release factor, score 1.6e-20
550537001598	PS00745 Prokaryotic-type class I peptide chain release factors signature.
550537001599	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
550537001600	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
550537001601	metal binding site [ion binding]; metal-binding site
550537001602	dimer interface [polypeptide binding]; other site
550537001603	HMMPfam hit to PF01546, Peptidase M20, score 2e-11
550537001604	HMMPfam hit to PF07687, Peptidase M20, dimerisation, score 1.3e-16
550537001605	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537001606	active site
550537001607	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 3.1e-19
550537001608	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
550537001609	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
550537001610	HMMPfam hit to PF06500, Protein of unknown function DUF1100, hydrolase-like, score 2.6e-298
550537001611	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
550537001612	HMMPfam hit to PF07417, Transcriptional regulator Crl, score 6.4e-93
550537001613	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537001614	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
550537001615	trimer interface [polypeptide binding]; other site
550537001616	eyelet of channel; other site
550537001617	HMMPfam hit to PF00267, Porin, Gram-negative type, score 3.8e-197
550537001618	PS00576 General diffusion Gram-negative porins signature.
550537001619	gamma-glutamyl kinase; Provisional; Region: PRK05429
550537001620	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
550537001621	nucleotide binding site [chemical binding]; other site
550537001622	homotetrameric interface [polypeptide binding]; other site
550537001623	putative phosphate binding site [ion binding]; other site
550537001624	putative allosteric binding site; other site
550537001625	PUA domain; Region: PUA; pfam01472
550537001626	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 1.5e-59
550537001627	PS00902 Glutamate 5-kinase signature.
550537001628	HMMPfam hit to PF01472, PUA, score 3.9e-29
550537001629	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
550537001630	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
550537001631	putative catalytic cysteine [active]
550537001632	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 8.8e-07
550537001633	PS01223 Gamma-glutamyl phosphate reductase signature.
550537001635	Transposase; Region: HTH_Tnp_1; cl17663
550537001636	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
550537001637	HMMPfam hit to PF01527, Transposase IS3/IS911, score 9.3e-11
550537001638	HMMPfam hit to PF08841, Diol/glycerol dehydratase reactivating factor, large subunit, score 7.7e-63; The upstream insertion of an IS3 element has resulted in the deletion of the 5' end of this CDS
550537001639	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
550537001640	HMMPfam hit to PF08986, Protein of unknown function DUF1889, score 1.1e-56
550537001641	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
550537001642	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537001643	putative substrate translocation pore; other site
550537001644	12 probable transmembrane helices predicted for SEN0311 by TMHMM2.0 at aa 26-48, 68-90, 97-119, 123-145, 152-174, 184-206, 236-258, 268-290, 297-319, 323-345, 362-384 and 388-410
550537001645	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.7e-40
550537001646	PS00216 Sugar transport proteins signature 1.
550537001647	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
550537001648	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
550537001649	substrate binding site [chemical binding]; other site
550537001650	ligand binding site [chemical binding]; other site
550537001651	HMMPfam hit to PF00330, Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, score 1.1e-184
550537001652	PS00450 Aconitase family signature 1.
550537001653	PS01244 Aconitase family signature 2.
550537001654	3-isopropylmalate dehydratase small subunit [Amino acid transport and metabolism]; Region: LeuD; COG0066
550537001655	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
550537001656	hypothetical protein; Provisional; Region: PRK14812
550537001657	substrate binding site [chemical binding]; other site
550537001658	HMMPfam hit to PF00694, Aconitase A/isopropylmalate dehydratase small subunit, swivel, score 1.9e-33
550537001659	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
550537001660	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
550537001661	HMMPfam hit to PF01557, Fumarylacetoacetase, C-terminal-like, score 4e-41
550537001662	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
550537001663	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 1.1e-20
550537001664	transcriptional activator TtdR; Provisional; Region: PRK09801
550537001665	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537001666	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
550537001667	putative effector binding pocket; other site
550537001668	putative dimerization interface [polypeptide binding]; other site
550537001669	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.3e-15
550537001670	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.7e-37
550537001671	YjzC-like protein; Region: YjzC; pfam14168
550537001672	fimbrial operon stb
550537001673	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
550537001674	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537001675	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537001676	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 2e-08
550537001677	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 8.8e-31
550537001678	PS00635 Gram-negative pili assembly chaperone signature.
550537001679	1 probable transmembrane helix predicted for SEN0319 by TMHMM2.0 at aa 7-29
550537001680	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
550537001681	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.006
550537001682	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001683	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
550537001684	PapC N-terminal domain; Region: PapC_N; pfam13954
550537001685	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537001686	PapC C-terminal domain; Region: PapC_C; pfam13953
550537001687	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 1.2e-231
550537001688	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537001689	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
550537001690	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537001691	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537001692	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 1.5e-07
550537001693	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 4e-49
550537001694	PS00635 Gram-negative pili assembly chaperone signature.
550537001695	1 probable transmembrane helix predicted for SEN0322 by TMHMM2.0 at aa 9-31
550537001696	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
550537001697	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 1.1e-20
550537001698	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
550537001699	1 probable transmembrane helix predicted for SEN0324 by TMHMM2.0 at aa 145-167
550537001700	1 probable transmembrane helix predicted for SEN0325 by TMHMM2.0 at aa 7-29
550537001701	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
550537001702	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537001703	2 probable transmembrane helices predicted for SEN0326 by TMHMM2.0 at aa 7-29 and 223-245
550537001704	HMMPfam hit to PF00563, EAL, score 2.8e-98
550537001705	PS00136 Serine proteases, subtilase family, aspartic acid active site.
550537001706	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
550537001707	DNA binding site [nucleotide binding]
550537001708	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 7.2e-08
550537001709	1 probable transmembrane helix predicted for SEN0328 by TMHMM2.0 at aa 7-29
550537001710	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
550537001711	HMMPfam hit to PF06316, Virulence-related outer membrane protein, score 9.1e-13
550537001712	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
550537001713	DNA binding residues [nucleotide binding]
550537001714	dimerization interface [polypeptide binding]; other site
550537001715	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
550537001716	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001717	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
550537001718	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.7e-44
550537001719	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.5e-35
550537001720	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001721	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
550537001722	HMMPfam hit to PF00873, Acriflavin resistance protein, score 0
550537001723	12 probable transmembrane helices predicted for SEN0334 by TMHMM2.0 at aa 7-29, 339-361, 368-390, 394-416, 443-465, 475-497, 543-565, 882-899, 906-928, 933-955, 983-1005 and 1015-1037
550537001724	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537001725	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
550537001726	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537001727	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537001728	HMMPfam hit to PF00529, Secretion protein HlyD, score 1.5e-35
550537001729	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
550537001730	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
550537001731	metal-binding site [ion binding]
550537001732	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
550537001733	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537001734	motif II; other site
550537001735	HMMPfam hit to PF00403, Heavy metal transport/detoxification protein, score 5.3e-20
550537001736	PS01047 Heavy-metal-associated domain.
550537001737	8 probable transmembrane helices predicted for SEN0336 by TMHMM2.0 at aa 99-121, 136-156, 169-191, 201-219, 353-375, 380-402, 696-718 and 722-744
550537001738	HMMPfam hit to PF00122, E1-E2 ATPase-associated region, score 1e-103
550537001739	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001740	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.2e-36
550537001741	PS00154 E1-E2 ATPases phosphorylation site.
550537001742	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
550537001743	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
550537001744	DNA binding residues [nucleotide binding]
550537001745	dimer interface [polypeptide binding]; other site
550537001746	copper binding site [ion binding]; other site
550537001747	HMMPfam hit to PF00376, Bacterial regulatory protein, MerR, score 1.6e-13
550537001748	HMMPfam hit to PF09278, Transcription regulator MerR, DNA binding, score 7.5e-27
550537001749	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
550537001750	metal-binding site [ion binding]
550537001751	HMMPfam hit to PF00403, Heavy metal transport/detoxification protein, score 0.0014
550537001752	putative sialic acid transporter; Region: 2A0112; TIGR00891
550537001753	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537001754	putative substrate translocation pore; other site
550537001755	10 probable transmembrane helices predicted for SEN0339 by TMHMM2.0 at aa 13-35, 50-72, 79-101, 105-127, 140-162, 172-194, 215-232, 252-274, 287-309 and 370-392
550537001756	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5.6e-39
550537001757	PS00217 Sugar transport proteins signature 2.
550537001758	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
550537001759	DNA methylase; Region: N6_N4_Mtase; cl17433
550537001760	DNA methylase; Region: N6_N4_Mtase; pfam01555
550537001761	HMMPfam hit to PF01555, DNA methylase N-4/N-6, score 1.4e-95
550537001762	PS00092 N-6 Adenine-specific DNA methylases signature.
550537001763	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
550537001764	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
550537001765	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
550537001766	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
550537001767	VRR-NUC domain; Region: VRR_NUC; pfam08774
550537001768	HMMPfam hit to PF04851, Restriction endonuclease, type I, R subunit/Type III, Res subunit, score 4.1e-47
550537001769	HMMPfam hit to PF08774, VRR-NUC, score 3.8e-06
550537001770	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
550537001771	HMMPfam hit to PF01654, Cytochrome bd ubiquinol oxidase, subunit I, score 1.1e-238
550537001772	9 probable transmembrane helices predicted for SEN0343 by TMHMM2.0 at aa 20-42, 55-77, 97-119, 126-148, 185-207, 220-237, 322-344, 357-379 and 407-429
550537001773	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
550537001774	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
550537001775	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
550537001776	HMMPfam hit to PF02322, Cytochrome bd ubiquinol oxidase, subunit II, score 2.4e-148
550537001777	8 probable transmembrane helices predicted for SEN0344 by TMHMM2.0 at aa 7-26, 78-100, 121-143, 158-180, 193-215, 230-248, 261-283 and 303-325
550537001778	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537001779	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537001780	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.00013
550537001781	PS00041 Bacterial regulatory proteins, araC family signature.
550537001782	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.00017
550537001783	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
550537001784	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537001785	N-terminal plug; other site
550537001786	ligand-binding site [chemical binding]; other site
550537001787	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 5.2e-26
550537001788	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 1.3e-27
550537001789	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
550537001790	HMMPfam hit to PF01810, Lysine exporter protein (LYSE/YGGA), score 9.1e-68
550537001791	6 probable transmembrane helices predicted for SEN0348 by TMHMM2.0 at aa 5-27, 39-61, 71-90, 123-140, 150-167 and 187-204
550537001792	hypothetical protein; Provisional; Region: PRK09929
550537001793	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 5e-14
550537001794	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
550537001795	Propionate catabolism activator; Region: PrpR_N; pfam06506
550537001796	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537001797	Walker A motif; other site
550537001798	ATP binding site [chemical binding]; other site
550537001799	Walker B motif; other site
550537001800	arginine finger; other site
550537001801	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
550537001802	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 4.3e-11
550537001803	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537001804	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 1.8e-127
550537001805	PS00134 Serine proteases, trypsin family, histidine active site.
550537001806	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537001807	HMMPfam hit to PF06506, Propionate catabolism activator, N-terminal, score 4.5e-104
550537001808	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
550537001809	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
550537001810	tetramer interface [polypeptide binding]; other site
550537001811	active site
550537001812	Mg2+/Mn2+ binding site [ion binding]; other site
550537001813	HMMPfam hit to PF00463, Isocitrate lyase and phosphorylmutase, score 1.4e-08
550537001814	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
550537001815	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
550537001816	dimer interface [polypeptide binding]; other site
550537001817	active site
550537001818	citrylCoA binding site [chemical binding]; other site
550537001819	oxalacetate/citrate binding site [chemical binding]; other site
550537001820	coenzyme A binding site [chemical binding]; other site
550537001821	catalytic triad [active]
550537001822	HMMPfam hit to PF00285, Citrate synthase, score 3.7e-101
550537001823	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001824	PS00480 Citrate synthase signature.
550537001825	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
550537001826	2-methylcitrate dehydratase; Region: prpD; TIGR02330
550537001827	HMMPfam hit to PF03972, MmgE/PrpD, score 4.1e-242
550537001828	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
550537001829	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
550537001830	acyl-activating enzyme (AAE) consensus motif; other site
550537001831	AMP binding site [chemical binding]; other site
550537001832	active site
550537001833	CoA binding site [chemical binding]; other site
550537001834	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 4e-111
550537001835	PS00455  AMP-binding domain signature.
550537001836	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
550537001837	dimer interface [polypeptide binding]; other site
550537001838	active site
550537001839	Schiff base residues; other site
550537001840	HMMPfam hit to PF00490, Tetrapyrrole biosynthesis, porphobilinogen synthase, score 1.6e-224
550537001841	PS00169 Delta-aminolevulinic acid dehydratase active site.
550537001842	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
550537001843	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
550537001844	Autotransporter beta-domain; Region: Autotransporter; pfam03797
550537001845	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001846	HMMPfam hit to PF03797, Autotransporter beta-domain, score 5.6e-33
550537001847	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
550537001848	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
550537001849	ligand binding site [chemical binding]; other site
550537001850	flexible hinge region; other site
550537001851	HMMPfam hit to PF00027, Cyclic nucleotide-binding, score 6.4e-08
550537001852	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
550537001853	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
550537001854	HMMPfam hit to PF00144, Beta-lactamase, score 3.7e-71
550537001855	microcin B17 transporter; Reviewed; Region: PRK11098
550537001856	6 probable transmembrane helices predicted for SEN0359 by TMHMM2.0 at aa 23-45, 52-74, 104-126, 172-194, 209-231 and 299-321
550537001857	HMMPfam hit to PF05992, SbmABacA-like, score 8.6e-242
550537001858	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
550537001859	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001860	HMMPfam hit to PF07759, Protein of unknown function DUF1615, score 6.4e-245
550537001861	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001862	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
550537001863	2 probable transmembrane helices predicted for SEN0361 by TMHMM2.0 at aa 25-47 and 68-90
550537001864	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001865	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
550537001866	2 probable transmembrane helices predicted for SEN0362 by TMHMM2.0 at aa 13-32 and 37-59
550537001867	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
550537001868	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
550537001869	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
550537001870	HMMPfam hit to PF07478, D-alanine--D-alanine ligase, C-terminal, score 1.5e-124
550537001871	PS00844 D-alanine--D-alanine ligase signature 2.
550537001872	HMMPfam hit to PF01820, D-alanine--D-alanine ligase, N-terminal, score 2.1e-83
550537001873	PS00843 D-alanine--D-alanine ligase signature 1.
550537001874	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001875	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
550537001876	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
550537001877	1 probable transmembrane helix predicted for SEN0364 by TMHMM2.0 at aa 13-35
550537001878	HMMPfam hit to PF06904, Extensin-like, C-terminal, score 1.5e-70
550537001879	drug efflux system protein MdtG; Provisional; Region: PRK09874
550537001880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537001881	putative substrate translocation pore; other site
550537001882	10 probable transmembrane helices predicted for SEN0365 by TMHMM2.0 at aa 7-29, 44-66, 79-101, 161-183, 204-226, 249-271, 283-302, 307-329, 342-364 and 369-391
550537001883	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.9e-49
550537001884	anti-RssB factor; Provisional; Region: PRK10244
550537001885	hypothetical protein; Provisional; Region: PRK11505
550537001886	psiF repeat; Region: PsiF_repeat; pfam07769
550537001887	psiF repeat; Region: PsiF_repeat; pfam07769
550537001888	1 probable transmembrane helix predicted for SEN0367 by TMHMM2.0 at aa 5-22
550537001889	HMMPfam hit to PF07769, PsiF, score 4.4e-18
550537001890	HMMPfam hit to PF07769, PsiF, score 5.6e-22
550537001891	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
550537001892	MASE2 domain; Region: MASE2; pfam05230
550537001893	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537001894	metal binding site [ion binding]; metal-binding site
550537001895	active site
550537001896	I-site; other site
550537001897	HMMPfam hit to PF05230, MASE2, score 2.3e-118
550537001898	4 probable transmembrane helices predicted for SEN0368 by TMHMM2.0 at aa 45-67, 105-127, 140-162 and 177-199
550537001899	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001900	HMMPfam hit to PF00990, GGDEF, score 5.9e-66
550537001901	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
550537001902	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
550537001903	HMMPfam hit to PF03807, NADP oxidoreductase, coenzyme F420-dependent, score 7.4e-99
550537001904	PS00521 Delta 1-pyrroline-5-carboxylate reductase signature.
550537001905	hypothetical protein; Validated; Region: PRK00124
550537001906	HMMPfam hit to PF02639, Protein of unknown function DUF188, score 8.4e-91
550537001907	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
550537001908	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
550537001909	ADP binding site [chemical binding]; other site
550537001910	magnesium binding site [ion binding]; other site
550537001911	putative shikimate binding site; other site
550537001912	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001913	HMMPfam hit to PF01202, Shikimate kinase, score 1.5e-67
550537001914	PS01128 Shikimate kinase signature.
550537001915	hypothetical protein; Provisional; Region: PRK10380
550537001916	hypothetical protein; Provisional; Region: PRK10481
550537001917	HMMPfam hit to PF07302, AroM, score 1.4e-149
550537001918	hypothetical protein; Provisional; Region: PRK10579
550537001919	HMMPfam hit to PF06865, Protein of unknown function DUF1255, score 4.2e-62
550537001920	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
550537001921	HMMPfam hit to PF04381,  exonuclease, RdgC, score 3.5e-213
550537001922	fructokinase; Reviewed; Region: PRK09557
550537001923	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537001924	nucleotide binding site [chemical binding]; other site
550537001925	HMMPfam hit to PF00480, ROK, score 2.3e-92
550537001926	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001927	PS01125 ROK family signature.
550537001928	MFS transport protein AraJ; Provisional; Region: PRK10091
550537001929	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537001930	putative substrate translocation pore; other site
550537001931	12 probable transmembrane helices predicted for SEN0377 by TMHMM2.0 at aa 5-27, 42-64, 71-93, 103-120, 125-147, 157-179, 200-222, 237-254, 266-288, 293-315, 320-342 and 352-374
550537001932	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 8.6e-47
550537001933	exonuclease subunit SbcC; Provisional; Region: PRK10246
550537001934	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537001935	Walker A/P-loop; other site
550537001936	ATP binding site [chemical binding]; other site
550537001937	Q-loop/lid; other site
550537001938	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537001939	ABC transporter signature motif; other site
550537001940	Walker B; other site
550537001941	D-loop; other site
550537001942	H-loop/switch region; other site
550537001943	HMMPfam hit to PF02463, SMC protein, N-terminal, score 1.6e-06
550537001944	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001945	PS00017 ATP/GTP-binding site motif A (P-loop).
550537001946	exonuclease subunit SbcD; Provisional; Region: PRK10966
550537001947	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
550537001948	active site
550537001949	metal binding site [ion binding]; metal-binding site
550537001950	DNA binding site [nucleotide binding]
550537001951	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
550537001952	HMMPfam hit to PF00149, Metallophosphoesterase, score 2.1e-20
550537001953	transcriptional regulator PhoB; Provisional; Region: PRK10161
550537001954	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537001955	active site
550537001956	phosphorylation site [posttranslational modification]
550537001957	intermolecular recognition site; other site
550537001958	dimerization interface [polypeptide binding]; other site
550537001959	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537001960	DNA binding site [nucleotide binding]
550537001961	HMMPfam hit to PF00072, Response regulator receiver, score 9.8e-41
550537001962	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 9.9e-24
550537001963	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
550537001964	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
550537001965	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537001966	putative active site [active]
550537001967	heme pocket [chemical binding]; other site
550537001968	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537001969	dimer interface [polypeptide binding]; other site
550537001970	phosphorylation site [posttranslational modification]
550537001971	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537001972	ATP binding site [chemical binding]; other site
550537001973	Mg2+ binding site [ion binding]; other site
550537001974	G-X-G motif; other site
550537001975	1 probable transmembrane helix predicted for SEN0381 by TMHMM2.0 at aa 12-34
550537001976	HMMPfam hit to PF00989, PAS fold, score 1.8e-17
550537001977	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.6e-24
550537001978	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 3.2e-42
550537001979	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
550537001980	HMMPfam hit to PF05525, Branched-chain amino acid transport system II carrier protein, score 4e-240
550537001981	12 probable transmembrane helices predicted for SEN0382 by TMHMM2.0 at aa 13-35, 41-63, 76-98, 118-140, 147-169, 189-211, 223-245, 276-298, 305-327, 337-359, 371-393 and 408-426
550537001982	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001983	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537001984	putative proline-specific permease; Provisional; Region: proY; PRK10580
550537001985	HMMPfam hit to PF00324, Amino acid permease-associated region, score 2.6e-136
550537001986	12 probable transmembrane helices predicted for SEN0383 by TMHMM2.0 at aa 16-34, 44-63, 83-105, 120-142, 154-176, 196-218, 239-261, 276-298, 329-351, 356-378, 399-421 and 426-445
550537001987	PS00218 Amino acid permeases signature.
550537001988	maltodextrin glucosidase; Provisional; Region: PRK10785
550537001989	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
550537001990	homodimer interface [polypeptide binding]; other site
550537001991	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
550537001992	active site
550537001993	homodimer interface [polypeptide binding]; other site
550537001994	catalytic site [active]
550537001995	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 1.1e-105
550537001996	peroxidase; Provisional; Region: PRK15000
550537001997	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
550537001998	dimer interface [polypeptide binding]; other site
550537001999	decamer (pentamer of dimers) interface [polypeptide binding]; other site
550537002000	catalytic triad [active]
550537002001	peroxidatic and resolving cysteines [active]
550537002002	HMMPfam hit to PF00578, Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen, score 9.5e-47
550537002003	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
550537002004	HMMPfam hit to PF04336, Protein of unknown function DUF479, score 1e-116
550537002005	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
550537002006	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
550537002007	HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 1.9e-149
550537002008	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
550537002009	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
550537002010	HMMPfam hit to PF01702, Queuine/other tRNA-ribosyltransferase, score 2e-170
550537002011	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
550537002012	HMMPfam hit to PF02699, YajC, score 4.4e-47
550537002013	1 probable transmembrane helix predicted for SEN0389 by TMHMM2.0 at aa 20-39
550537002014	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
550537002015	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
550537002016	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
550537002017	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
550537002018	6 probable transmembrane helices predicted for SEN0390 by TMHMM2.0 at aa 7-29, 452-471, 476-498, 503-525, 546-568 and 583-605
550537002019	HMMPfam hit to PF07549, SecD/SecF/SecDF export membrane protein, score 6.5e-05
550537002020	PS00761 Signal peptidases I signature 3.
550537002021	HMMPfam hit to PF02355, SecD/SecF/SecDF export membrane protein, score 5.1e-06
550537002022	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
550537002023	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
550537002024	Protein export membrane protein; Region: SecD_SecF; pfam02355
550537002025	6 probable transmembrane helices predicted for SEN0391 by TMHMM2.0 at aa 24-46, 143-162, 169-191, 195-217, 248-270 and 275-297
550537002026	HMMPfam hit to PF07549, SecD/SecF/SecDF export membrane protein, score 0.00021
550537002027	HMMPfam hit to PF02355, SecD/SecF/SecDF export membrane protein, score 4.6e-94
550537002028	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
550537002029	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
550537002030	HMMPfam hit to PF00903, Glyoxalase/bleomycin resistance protein/dioxygenase, score 6.7e-08
550537002031	Predicted transcriptional regulator [Transcription]; Region: COG2378
550537002032	HTH domain; Region: HTH_11; pfam08279
550537002033	WYL domain; Region: WYL; pfam13280
550537002034	HMMPfam hit to PF08279, Helix-turn-helix, type 11, score 4.1e-20
550537002035	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
550537002036	active site
550537002037	HMMPfam hit to PF01844, HNH endonuclease, score 6.2e-06
550537002038	PS00190 Cytochrome c family heme-binding site signature.
550537002039	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
550537002040	HMMPfam hit to PF03502, Nucleoside-specific channel-forming protein, Tsx, score 4.6e-100
550537002041	hypothetical protein; Provisional; Region: PRK11530
550537002042	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002043	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
550537002044	ATP cone domain; Region: ATP-cone; pfam03477
550537002045	HMMPfam hit to PF03477, ATP-cone, score 2.2e-35
550537002046	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
550537002047	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
550537002048	catalytic motif [active]
550537002049	Zn binding site [ion binding]; other site
550537002050	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
550537002051	HMMPfam hit to PF00383, CMP/dCMP deaminase, zinc-binding, score 3.9e-47
550537002052	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
550537002053	HMMPfam hit to PF01872, Bacterial bifunctional deaminase-reductase, C-terminal, score 3.9e-90
550537002054	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
550537002055	homopentamer interface [polypeptide binding]; other site
550537002056	active site
550537002057	HMMPfam hit to PF00885, 6,7-dimethyl-8-ribityllumazine synthase, score 1.9e-90
550537002058	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
550537002059	putative RNA binding site [nucleotide binding]; other site
550537002060	HMMPfam hit to PF01029, NusB/RsmB/TIM44, score 5.7e-50
550537002061	thiamine monophosphate kinase; Provisional; Region: PRK05731
550537002062	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
550537002063	ATP binding site [chemical binding]; other site
550537002064	dimerization interface [polypeptide binding]; other site
550537002065	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal, score 1.9e-10
550537002066	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
550537002067	tetramer interfaces [polypeptide binding]; other site
550537002068	binuclear metal-binding site [ion binding]; other site
550537002069	HMMPfam hit to PF04608, Phosphatidylglycerophosphatase A, score 1.5e-77
550537002070	3 probable transmembrane helices predicted for SEN0402 by TMHMM2.0 at aa 21-43, 53-75 and 140-162
550537002071	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537002072	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537002073	active site
550537002074	catalytic tetrad [active]
550537002075	HMMPfam hit to PF00248, Aldo/keto reductase, score 5.3e-66
550537002076	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
550537002077	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
550537002078	TPP-binding site; other site
550537002079	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
550537002080	PYR/PP interface [polypeptide binding]; other site
550537002081	dimer interface [polypeptide binding]; other site
550537002082	TPP binding site [chemical binding]; other site
550537002083	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
550537002084	HMMPfam hit to PF02780, Transketolase, C-terminal, score 1e-37
550537002085	HMMPfam hit to PF02779, Transketolase, central region, score 3.6e-59
550537002086	PS00802 Transketolase signature 2.
550537002087	PS00801 Transketolase signature 1.
550537002088	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
550537002089	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
550537002090	substrate binding pocket [chemical binding]; other site
550537002091	chain length determination region; other site
550537002092	substrate-Mg2+ binding site; other site
550537002093	catalytic residues [active]
550537002094	aspartate-rich region 1; other site
550537002095	active site lid residues [active]
550537002096	aspartate-rich region 2; other site
550537002097	HMMPfam hit to PF00348, Polyprenyl synthetase, score 9.5e-131
550537002098	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002099	PS00444 Polyprenyl synthetases signature 2.
550537002100	PS00723 Polyprenyl synthetases signature 1.
550537002101	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
550537002102	HMMPfam hit to PF02609, Exonuclease VII, small subunit, score 1.8e-33
550537002103	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
550537002104	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
550537002105	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
550537002106	Ligand Binding Site [chemical binding]; other site
550537002107	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
550537002108	active site residue [active]
550537002109	HMMPfam hit to PF02926, THUMP, score 2e-28
550537002110	HMMPfam hit to PF02568, Thiamine biosynthesis protein, score 4.9e-110
550537002111	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
550537002112	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537002113	dimer interface [polypeptide binding]; other site
550537002114	conserved gate region; other site
550537002115	putative PBP binding loops; other site
550537002116	ABC-ATPase subunit interface; other site
550537002117	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 5.1e-17
550537002118	6 probable transmembrane helices predicted for SEN0408 by TMHMM2.0 at aa 12-34, 66-88, 101-123, 133-155, 191-213 and 233-255
550537002119	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
550537002120	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537002121	dimer interface [polypeptide binding]; other site
550537002122	conserved gate region; other site
550537002123	putative PBP binding loops; other site
550537002124	ABC-ATPase subunit interface; other site
550537002125	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.1e-14
550537002126	7 probable transmembrane helices predicted for SEN0409 by TMHMM2.0 at aa 15-37, 74-96, 111-133, 140-162, 199-221, 226-245 and 255-277
550537002127	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537002128	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002129	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
550537002130	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537002131	Walker A/P-loop; other site
550537002132	ATP binding site [chemical binding]; other site
550537002133	Q-loop/lid; other site
550537002134	ABC transporter signature motif; other site
550537002135	Walker B; other site
550537002136	D-loop; other site
550537002137	H-loop/switch region; other site
550537002138	TOBE domain; Region: TOBE_2; pfam08402
550537002139	HMMPfam hit to PF08402, Transport-associated OB, type 2, score 5.8e-18
550537002140	HMMPfam hit to PF00005, ABC transporter related, score 2.4e-60
550537002141	PS00211 ABC transporters family signature.
550537002142	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002143	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
550537002144	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
550537002145	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 4.2e-15
550537002146	transcriptional regulator protein; Region: phnR; TIGR03337
550537002147	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537002148	DNA-binding site [nucleotide binding]; DNA binding site
550537002149	UTRA domain; Region: UTRA; pfam07702
550537002150	HMMPfam hit to PF07702, UbiC transcription regulator-associated, score 9e-45
550537002151	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 1.5e-23
550537002152	PS00043 Bacterial regulatory proteins, gntR family signature.
550537002153	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
550537002154	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537002155	catalytic residue [active]
550537002156	HMMPfam hit to PF00266, Aminotransferase, class V, score 1.5e-08
550537002157	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
550537002158	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537002159	motif II; other site
550537002160	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 6.8e-20
550537002161	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
550537002162	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
550537002163	conserved cys residue [active]
550537002164	HMMPfam hit to PF01965, ThiJ/PfpI, score 5.1e-47
550537002165	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
550537002166	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
550537002167	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
550537002168	HMMPfam hit to PF08546, Ketopantoate reductase ApbA/PanE, C-terminal, score 9e-59
550537002169	HMMPfam hit to PF02558, Ketopantoate reductase ApbA/PanE, N-terminal, score 1.4e-37
550537002170	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
550537002171	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
550537002172	HMMPfam hit to PF04461, Protein of unknown function DUF520, score 1.7e-112
550537002173	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537002174	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537002175	putative substrate translocation pore; other site
550537002176	12 probable transmembrane helices predicted for SEN0418 by TMHMM2.0 at aa 13-35, 50-72, 79-98, 102-124, 137-159, 164-186, 217-239, 254-273, 280-302, 306-328, 341-363 and 368-385
550537002177	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.8e-46
550537002178	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537002179	Sel1-like repeats; Region: SEL1; smart00671
550537002180	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537002181	Sel1 repeat; Region: Sel1; pfam08238
550537002182	Sel1-like repeats; Region: SEL1; smart00671
550537002183	HMMPfam hit to PF08238, Sel1-like, score 0.00063
550537002184	HMMPfam hit to PF08238, Sel1-like, score 4.3e-07
550537002185	HMMPfam hit to PF08238, Sel1-like, score 0.083
550537002186	HMMPfam hit to PF08238, Sel1-like, score 0.78
550537002187	note the premature stop codon following codon 135
550537002188	HMMPfam hit to PF08238, Sel1-like, score 0.5
550537002189	HMMPfam hit to PF08238, Sel1-like, score 1.2
550537002190	HMMPfam hit to PF08238, Sel1-like, score 7.5e-09
550537002191	HMMPfam hit to PF08238, Sel1-like, score 5.4e-06
550537002192	HMMPfam hit to PF08238, Sel1-like, score 1.8
550537002193	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
550537002194	UbiA prenyltransferase family; Region: UbiA; pfam01040
550537002195	9 probable transmembrane helices predicted for SEN0421 by TMHMM2.0 at aa 12-34, 38-60, 81-103, 108-127, 134-156, 161-183, 209-231, 235-252 and 264-286
550537002196	HMMPfam hit to PF01040, UbiA prenyltransferase, score 2.3e-90
550537002197	PS00141 Eukaryotic and viral aspartyl proteases active site.
550537002198	PS00943 UbiA prenyltransferase family signature.
550537002199	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002200	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
550537002201	HMMPfam hit to PF03626, Cytochrome C oxidase subunit IV prokaryotic, score 7e-52
550537002202	3 probable transmembrane helices predicted for SEN0422 by TMHMM2.0 at aa 15-37, 44-66 and 76-98
550537002203	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
550537002204	Subunit III/IV interface [polypeptide binding]; other site
550537002205	Subunit I/III interface [polypeptide binding]; other site
550537002206	HMMPfam hit to PF00510, Cytochrome c oxidase, subunit III, score 3.2e-05
550537002207	5 probable transmembrane helices predicted for SEN0423 by TMHMM2.0 at aa 5-24, 34-56, 63-85, 105-127 and 148-170
550537002208	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
550537002209	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
550537002210	D-pathway; other site
550537002211	Putative ubiquinol binding site [chemical binding]; other site
550537002212	Low-spin heme (heme b) binding site [chemical binding]; other site
550537002213	Putative water exit pathway; other site
550537002214	Binuclear center (heme o3/CuB) [ion binding]; other site
550537002215	K-pathway; other site
550537002216	Putative proton exit pathway; other site
550537002217	14 probable transmembrane helices predicted for SEN0424 by TMHMM2.0 at aa 15-37, 57-79, 105-127, 140-162, 191-213, 233-255, 275-297, 310-332, 347-369, 382-404, 414-436, 456-478, 498-520 and 590-612
550537002218	HMMPfam hit to PF00115, Cytochrome c oxidase, subunit I, score 3.1e-268
550537002219	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002220	PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature.
550537002221	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
550537002222	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
550537002223	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
550537002224	HMMPfam hit to PF06481, COX aromatic rich, score 1.8e-16
550537002225	HMMPfam hit to PF00116, Cytochrome c oxidase subunit II C-terminal, score 4e-06
550537002226	3 probable transmembrane helices predicted for SEN0425 by TMHMM2.0 at aa 12-30, 45-67 and 88-110
550537002227	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002228	muropeptide transporter; Reviewed; Region: ampG; PRK11902
550537002229	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537002230	putative substrate translocation pore; other site
550537002231	14 probable transmembrane helices predicted for SEN0426 by TMHMM2.0 at aa 13-35, 50-69, 82-104, 109-131, 144-166, 176-195, 223-245, 260-282, 287-309, 319-341, 354-376, 380-402, 423-445 and 458-480
550537002232	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 7.3e-30
550537002233	hypothetical protein; Provisional; Region: PRK11627
550537002234	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
550537002235	HMMPfam hit to PF03923, Uncharacterized lipoprotein, score 1.7e-07
550537002236	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002237	transcriptional regulator BolA; Provisional; Region: PRK11628
550537002238	HMMPfam hit to PF01722, BolA-like protein, score 2.3e-37
550537002239	trigger factor; Provisional; Region: tig; PRK01490
550537002240	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
550537002241	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
550537002242	HMMPfam hit to PF05697, Bacterial trigger factor, N-terminal, score 4.8e-70
550537002243	HMMPfam hit to PF00254, Peptidyl-prolyl cis-trans isomerase, FKBP-type, score 1.1e-27
550537002244	HMMPfam hit to PF05698, Bacterial trigger factor, C-terminal, score 1.2e-60
550537002245	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
550537002246	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
550537002247	oligomer interface [polypeptide binding]; other site
550537002248	active site residues [active]
550537002249	HMMPfam hit to PF00574, Peptidase S14, ClpP, score 8e-140
550537002250	PS00381 Endopeptidase Clp serine active site.
550537002251	PS00382 Endopeptidase Clp histidine active site.
550537002252	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
550537002253	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
550537002254	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537002255	Walker A motif; other site
550537002256	ATP binding site [chemical binding]; other site
550537002257	Walker B motif; other site
550537002258	Iron permease FTR1 family; Region: FTR1; cl00475
550537002259	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
550537002260	HMMPfam hit to PF06689, Zinc finger, C4-type, score 5e-27
550537002261	HMMPfam hit to PF07724, ATPase AAA-2, score 4.7e-81
550537002262	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002263	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
550537002264	Found in ATP-dependent protease La (LON); Region: LON; smart00464
550537002265	Found in ATP-dependent protease La (LON); Region: LON; smart00464
550537002266	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537002267	Walker A motif; other site
550537002268	ATP binding site [chemical binding]; other site
550537002269	Walker B motif; other site
550537002270	arginine finger; other site
550537002271	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
550537002272	HMMPfam hit to PF02190, Peptidase S16, lon N-terminal, score 2.6e-84
550537002273	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537002274	HMMPfam hit to PF00004, AAA ATPase, core, score 2.6e-44
550537002275	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002276	HMMPfam hit to PF05362, Peptidase S16, lon C-terminal, score 5.5e-156
550537002277	PS01046 ATP-dependent serine proteases, lon family, serine active site.
550537002278	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002279	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
550537002280	IHF dimer interface [polypeptide binding]; other site
550537002281	IHF - DNA interface [nucleotide binding]; other site
550537002282	HMMPfam hit to PF00216, Histone-like bacterial DNA-binding protein, score 8.3e-47
550537002283	PS00045 Bacterial histone-like DNA-binding proteins signature.
550537002284	periplasmic folding chaperone; Provisional; Region: PRK10788
550537002285	SurA N-terminal domain; Region: SurA_N_3; cl07813
550537002286	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
550537002287	1 probable transmembrane helix predicted for SEN0434 by TMHMM2.0 at aa 13-35
550537002288	HMMPfam hit to PF00639, Peptidyl-prolyl cis-trans isomerase, PpiC-type, score 6.3e-16
550537002289	PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature.
550537002290	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
550537002291	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
550537002292	active site
550537002293	HMMPfam hit to PF03061, Thioesterase superfamily, score 7.8e-17
550537002294	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
550537002295	Ligand Binding Site [chemical binding]; other site
550537002296	HMMPfam hit to PF06508, Exoenzyme S synthesis protein B/queuosine synthesis, score 1.2e-113
550537002297	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
550537002298	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
550537002299	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
550537002300	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 2.9e-24
550537002301	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
550537002302	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537002303	active site
550537002304	motif I; other site
550537002305	motif II; other site
550537002306	PS01228 Hypothetical cof family signature 1.
550537002307	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 3.7e-67
550537002308	PS01229 Hypothetical cof family signature 2.
550537002309	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
550537002310	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
550537002311	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537002312	catalytic residue [active]
550537002313	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 1.1e-55
550537002314	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
550537002315	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537002316	putative DNA binding site [nucleotide binding]; other site
550537002317	putative Zn2+ binding site [ion binding]; other site
550537002318	AsnC family; Region: AsnC_trans_reg; pfam01037
550537002319	PS00519 Bacterial regulatory proteins, asnC family signature.
550537002320	HMMPfam hit to PF01037, Bacterial regulatory proteins, AsnC/Lrp, score 6.8e-29
550537002321	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
550537002322	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537002323	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537002324	Walker A/P-loop; other site
550537002325	ATP binding site [chemical binding]; other site
550537002326	Q-loop/lid; other site
550537002327	ABC transporter signature motif; other site
550537002328	Walker B; other site
550537002329	D-loop; other site
550537002330	H-loop/switch region; other site
550537002331	HMMPfam hit to PF00664, ABC transporter, transmembrane region, score 4e-35
550537002332	6 probable transmembrane helices predicted for SEN0442 by TMHMM2.0 at aa 21-43, 58-77, 129-151, 156-175, 246-268 and 278-300
550537002333	HMMPfam hit to PF00005, ABC transporter related, score 2.1e-58
550537002334	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002335	PS00211 ABC transporters family signature.
550537002336	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
550537002337	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537002338	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537002339	Walker A/P-loop; other site
550537002340	ATP binding site [chemical binding]; other site
550537002341	Q-loop/lid; other site
550537002342	ABC transporter signature motif; other site
550537002343	Walker B; other site
550537002344	D-loop; other site
550537002345	H-loop/switch region; other site
550537002346	HMMPfam hit to PF00664, ABC transporter, transmembrane region, score 1.7e-30
550537002347	5 probable transmembrane helices predicted for SEN0443 by TMHMM2.0 at aa 12-34, 54-76, 125-147, 152-172 and 236-258
550537002348	HMMPfam hit to PF00005, ABC transporter related, score 2.9e-48
550537002349	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002350	PS00211 ABC transporters family signature.
550537002351	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
550537002352	Nitrogen regulatory protein P-II; Region: P-II; smart00938
550537002353	HMMPfam hit to PF00543, Nitrogen regulatory protein PII, score 4.8e-72
550537002354	PS00496 P-II protein urydylation site.
550537002355	PS00638 P-II protein C-terminal region signature.
550537002356	ammonium transporter; Provisional; Region: PRK10666
550537002357	12 probable transmembrane helices predicted for SEN0445 by TMHMM2.0 at aa 9-26, 36-58, 63-85, 120-142, 149-171, 186-205, 218-237, 247-269, 281-303, 307-324, 337-359 and 374-396
550537002358	HMMPfam hit to PF00909, Rh-like protein/ammonium transporter, score 3.4e-187
550537002359	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002360	PS01219 Ammonium transporters signature.
550537002361	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002362	acyl-CoA thioesterase II; Provisional; Region: PRK10526
550537002363	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
550537002364	active site
550537002365	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
550537002366	catalytic triad [active]
550537002367	dimer interface [polypeptide binding]; other site
550537002368	HMMPfam hit to PF02551, Acyl-CoA thioesterase, score 4.6e-78
550537002369	HMMPfam hit to PF02551, Acyl-CoA thioesterase, score 3.9e-43
550537002370	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
550537002371	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002372	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
550537002373	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
550537002374	DNA binding site [nucleotide binding]
550537002375	active site
550537002376	HMMPfam hit to PF01035, Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding, score 3.4e-39
550537002377	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
550537002378	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
550537002379	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537002380	HMMPfam hit to PF00563, EAL, score 7.2e-111
550537002381	2 probable transmembrane helices predicted for SEN0449 by TMHMM2.0 at aa 6-28 and 243-265
550537002382	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
550537002383	HMMPfam hit to PF01197, Ribosomal protein L31, score 2.3e-11
550537002384	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
550537002385	HMMPfam hit to PF00444, Ribosomal protein L36, score 0.00024
550537002386	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
550537002387	2 probable transmembrane helices predicted for SEN0452 by TMHMM2.0 at aa 36-55 and 60-79
550537002388	maltose O-acetyltransferase; Provisional; Region: PRK10092
550537002389	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
550537002390	active site
550537002391	substrate binding site [chemical binding]; other site
550537002392	trimer interface [polypeptide binding]; other site
550537002393	CoA binding site [chemical binding]; other site
550537002394	PS00101 Hexapeptide-repeat containing-transferases signature.
550537002395	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.098
550537002396	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.83
550537002397	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.048
550537002398	gene expression modulator; Provisional; Region: PRK10945
550537002399	HMMPfam hit to PF05321, Haemolysin expression modulating, score 1.4e-37
550537002400	Hha toxicity attenuator; Provisional; Region: PRK10667
550537002401	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
550537002402	Protein export membrane protein; Region: SecD_SecF; cl14618
550537002403	Protein export membrane protein; Region: SecD_SecF; cl14618
550537002404	HMMPfam hit to PF00873, Acriflavin resistance protein, score 0
550537002405	11 probable transmembrane helices predicted for SEN0456 by TMHMM2.0 at aa 10-32, 340-359, 369-391, 438-460, 470-492, 542-564, 873-892, 899-921, 926-948, 975-997 and 1007-1029
550537002406	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002407	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
550537002408	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537002409	HMMPfam hit to PF00529, Secretion protein HlyD, score 4.4e-91
550537002410	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002411	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
550537002412	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537002413	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
550537002414	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 3.1e-24
550537002415	PS01081 Bacterial regulatory proteins, tetR family signature.
550537002416	HMMPfam hit to PF08361, Transcriptional regulator, MAATS, C-terminal, score 6.4e-84
550537002417	hypothetical protein; Provisional; Region: PRK11281
550537002418	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
550537002419	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
550537002420	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537002421	12 probable transmembrane helices predicted for SEN0459 by TMHMM2.0 at aa 13-32, 500-522, 557-579, 584-606, 630-647, 658-680, 693-715, 725-747, 795-817, 837-859, 880-902 and 917-939
550537002422	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002423	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 6.2e-87
550537002424	PS01246 Uncharacterized protein family UPF0003 signature.
550537002425	Uncharacterized conserved protein [Function unknown]; Region: COG5464
550537002426	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
550537002427	HMMPfam hit to PF04754, Transposase (), YhgA-like, score 7e-164
550537002428	hypothetical protein; Provisional; Region: PRK11038
550537002429	primosomal replication protein N''; Provisional; Region: PRK10093
550537002430	HMMPfam hit to PF07445, Primosomal replication priB and priC, score 5.7e-100
550537002431	hypothetical protein; Provisional; Region: PRK10527
550537002432	HMMPfam hit to PF04304, Protein of unknown function DUF454, score 6.7e-30
550537002433	2 probable transmembrane helices predicted for SEN0463 by TMHMM2.0 at aa 21-43 and 47-69
550537002434	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537002435	active site
550537002436	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 1.2e-51
550537002437	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
550537002438	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
550537002439	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537002440	Walker A motif; other site
550537002441	ATP binding site [chemical binding]; other site
550537002442	Walker B motif; other site
550537002443	DNA polymerase III subunit delta'; Validated; Region: PRK08485
550537002444	arginine finger; other site
550537002445	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
550537002446	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
550537002447	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
550537002448	HMMPfam hit to PF00004, AAA ATPase, core, score 1.9e-11
550537002449	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002450	hypothetical protein; Validated; Region: PRK00153
550537002451	HMMPfam hit to PF02575, Conserved hypothetical protein CHP00103, score 8.5e-53
550537002452	recombination protein RecR; Reviewed; Region: recR; PRK00076
550537002453	RecR protein; Region: RecR; pfam02132
550537002454	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
550537002455	putative active site [active]
550537002456	putative metal-binding site [ion binding]; other site
550537002457	tetramer interface [polypeptide binding]; other site
550537002458	HMMPfam hit to PF02132, Zinc finger C4-type, RecR, score 4.6e-22
550537002459	PS01300 RecR protein signature.
550537002460	HMMPfam hit to PF01751, TOPRIM, score 2.6e-24
550537002461	heat shock protein 90; Provisional; Region: PRK05218
550537002462	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537002463	ATP binding site [chemical binding]; other site
550537002464	Mg2+ binding site [ion binding]; other site
550537002465	G-X-G motif; other site
550537002466	PS00298 Heat shock hsp90 proteins family signature.
550537002467	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2.2e-17
550537002468	HMMPfam hit to PF00183, Heat shock protein Hsp90, score 2.1e-115
550537002469	adenylate kinase; Reviewed; Region: adk; PRK00279
550537002470	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
550537002471	AMP-binding site [chemical binding]; other site
550537002472	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
550537002473	HMMPfam hit to PF00406, Adenylate kinase, score 3.5e-100
550537002474	PS00113 Adenylate kinase signature.
550537002475	HMMPfam hit to PF05191, Adenylate kinase, lid region, score 1.7e-21
550537002476	ferrochelatase; Reviewed; Region: hemH; PRK00035
550537002477	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
550537002478	C-terminal domain interface [polypeptide binding]; other site
550537002479	active site
550537002480	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
550537002481	active site
550537002482	N-terminal domain interface [polypeptide binding]; other site
550537002483	HMMPfam hit to PF00762, Ferrochelatase, score 8.6e-159
550537002484	PS00534 Ferrochelatase signature.
550537002485	acetyl esterase; Provisional; Region: PRK10162
550537002486	HMMPfam hit to PF07859, Alpha/beta hydrolase fold-3, score 8.1e-68
550537002487	PS01174 Lipolytic enzymes G-D-X-G family,  serine active site.
550537002488	inosine/guanosine kinase; Provisional; Region: PRK15074
550537002489	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537002490	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 4.7e-23
550537002491	PS00584 pfkB family of carbohydrate kinases signature 2.
550537002492	putative cation:proton antiport protein; Provisional; Region: PRK10669
550537002493	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
550537002494	TrkA-N domain; Region: TrkA_N; pfam02254
550537002495	HMMPfam hit to PF02254, TrkA-N, score 1.7e-32
550537002496	12 probable transmembrane helices predicted for SEN0473 by TMHMM2.0 at aa 4-26, 33-52, 56-78, 87-109, 114-136, 149-171, 186-208, 229-251, 280-299, 302-324, 339-361 and 368-387
550537002497	HMMPfam hit to PF00999, Sodium/hydrogen exchanger, score 2.3e-86
550537002498	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002499	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537002500	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537002501	putative substrate translocation pore; other site
550537002502	10 probable transmembrane helices predicted for SEN0474 by TMHMM2.0 at aa 26-48, 58-80, 101-123, 180-202, 223-245, 265-287, 294-313, 317-339, 351-373 and 377-399
550537002503	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.4e-39
550537002504	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
550537002505	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
550537002506	active site
550537002507	metal binding site [ion binding]; metal-binding site
550537002508	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
550537002509	HMMPfam hit to PF00149, Metallophosphoesterase, score 1.7e-18
550537002510	PS00785 5'-nucleotidase signature 1.
550537002511	PS00786 5'-nucleotidase signature 2.
550537002512	HMMPfam hit to PF02872, 5'-Nucleotidase, C-terminal, score 1.7e-54
550537002513	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
550537002514	putative deacylase active site [active]
550537002515	HMMPfam hit to PF04073, YbaK/prolyl-tRNA synthetase associated region, score 1.3e-76
550537002516	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
550537002517	HMMPfam hit to PF07446, GumN, score 2.8e-06
550537002518	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
550537002519	copper exporting ATPase; Provisional; Region: copA; PRK10671
550537002520	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
550537002521	metal-binding site [ion binding]
550537002522	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
550537002523	metal-binding site [ion binding]
550537002524	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
550537002525	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537002526	motif II; other site
550537002527	8 probable transmembrane helices predicted for SEN0479 by TMHMM2.0 at aa 188-205, 215-237, 244-266, 281-298, 435-457, 462-484, 777-796 and 801-823
550537002528	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.8e-40
550537002529	PS01229 Hypothetical cof family signature 2.
550537002530	PS00154 E1-E2 ATPases phosphorylation site.
550537002531	HMMPfam hit to PF00122, E1-E2 ATPase-associated region, score 1.4e-98
550537002532	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002533	HMMPfam hit to PF00403, Heavy metal transport/detoxification protein, score 1.5e-14
550537002534	PS01047 Heavy-metal-associated domain.
550537002535	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002536	HMMPfam hit to PF00403, Heavy metal transport/detoxification protein, score 2.5e-09
550537002537	PS01047 Heavy-metal-associated domain.
550537002538	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
550537002539	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
550537002540	DNA binding residues [nucleotide binding]
550537002541	dimer interface [polypeptide binding]; other site
550537002542	copper binding site [ion binding]; other site
550537002543	HMMPfam hit to PF00376, Bacterial regulatory protein, MerR, score 4.3e-13
550537002544	PS00552 Bacterial regulatory proteins, merR family signature.
550537002545	HMMPfam hit to PF09278, Transcription regulator MerR, DNA binding, score 2.6e-19
550537002546	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
550537002547	HMMPfam hit to PF01957, Nodulation efficiency, NfeD, score 1.2e-33
550537002548	3 probable transmembrane helices predicted for SEN0481 by TMHMM2.0 at aa 4-23, 30-49 and 53-75
550537002549	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
550537002550	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
550537002551	HMMPfam hit to PF01145, Band 7 protein, score 3.7e-80
550537002552	PS01270 Band 7 protein family signature.
550537002553	1 probable transmembrane helix predicted for SEN0482 by TMHMM2.0 at aa 7-29
550537002554	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
550537002555	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
550537002556	Walker A/P-loop; other site
550537002557	ATP binding site [chemical binding]; other site
550537002558	Q-loop/lid; other site
550537002559	ABC transporter signature motif; other site
550537002560	Walker B; other site
550537002561	D-loop; other site
550537002562	H-loop/switch region; other site
550537002563	HMMPfam hit to PF00005, ABC transporter related, score 8.4e-39
550537002564	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002565	PS00211 ABC transporters family signature.
550537002566	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
550537002567	HMMPfam hit to PF03649, Conserved hypothetical protein CHP00245, score 1.6e-158
550537002568	6 probable transmembrane helices predicted for SEN0484 by TMHMM2.0 at aa 7-24, 57-79, 92-114, 118-140, 192-209 and 219-241
550537002569	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002570	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
550537002571	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
550537002572	HMMPfam hit to PF00085, Thioredoxin domain, score 2.6e-21
550537002573	oxidoreductase; Provisional; Region: PRK08017
550537002574	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
550537002575	NADP binding site [chemical binding]; other site
550537002576	active site
550537002577	steroid binding site; other site
550537002578	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 1e-21
550537002579	PS00061 Short-chain dehydrogenases/reductases family signature.
550537002580	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
550537002581	active site
550537002582	catalytic triad [active]
550537002583	oxyanion hole [active]
550537002584	switch loop; other site
550537002585	HMMPfam hit to PF00657, Lipolytic enzyme, G-D-S-L, score 1.3e-35
550537002586	PS01098 Lipolytic enzymes G-D-S-L family, serine active site.
550537002587	1 probable transmembrane helix predicted for SEN0487 by TMHMM2.0 at aa 7-26
550537002588	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
550537002589	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
550537002590	Walker A/P-loop; other site
550537002591	ATP binding site [chemical binding]; other site
550537002592	Q-loop/lid; other site
550537002593	ABC transporter signature motif; other site
550537002594	Walker B; other site
550537002595	D-loop; other site
550537002596	H-loop/switch region; other site
550537002597	HMMPfam hit to PF00005, ABC transporter related, score 8e-62
550537002598	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002599	PS00211 ABC transporters family signature.
550537002600	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
550537002601	FtsX-like permease family; Region: FtsX; pfam02687
550537002602	10 probable transmembrane helices predicted for SEN0489 by TMHMM2.0 at aa 13-35, 243-262, 291-313, 333-355, 376-398, 403-425, 451-473, 676-698, 732-754 and 769-791
550537002603	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002604	HMMPfam hit to PF02687, Protein of unknown function DUF214, permase predicted, score 1.1e-11
550537002605	HMMPfam hit to PF02687, Protein of unknown function DUF214, permase predicted, score 3.9e-08
550537002606	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537002607	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
550537002608	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
550537002609	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
550537002610	HMMPfam hit to PF03180, NLPA lipoprotein, score 1.5e-113
550537002611	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
550537002612	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
550537002613	Walker A/P-loop; other site
550537002614	ATP binding site [chemical binding]; other site
550537002615	Q-loop/lid; other site
550537002616	ABC transporter signature motif; other site
550537002617	Walker B; other site
550537002618	D-loop; other site
550537002619	H-loop/switch region; other site
550537002620	NIL domain; Region: NIL; pfam09383
550537002621	HMMPfam hit to PF00005, ABC transporter related, score 5.4e-70
550537002622	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002623	PS00211 ABC transporters family signature.
550537002624	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537002625	dimer interface [polypeptide binding]; other site
550537002626	conserved gate region; other site
550537002627	ABC-ATPase subunit interface; other site
550537002628	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 3.1e-20
550537002629	6 probable transmembrane helices predicted for SEN0493 by TMHMM2.0 at aa 15-37, 50-72, 82-104, 117-139, 149-171 and 183-205
550537002630	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537002631	Predicted ATPase [General function prediction only]; Region: COG2603
550537002632	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
550537002633	active site residue [active]
550537002634	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002635	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
550537002636	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537002637	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537002638	dimerization interface [polypeptide binding]; other site
550537002639	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.2e-13
550537002640	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2.4e-15
550537002641	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
550537002642	ureidoglycolate hydrolase; Provisional; Region: PRK03606
550537002643	HMMPfam hit to PF04115, Ureidoglycolate hydrolase, score 5.2e-90
550537002644	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
550537002645	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
550537002646	Bacterial transcriptional regulator; Region: IclR; pfam01614
550537002647	HMMPfam hit to PF09339, Transcriptional regulator IclR, N-terminal, score 2.8e-22
550537002648	HMMPfam hit to PF01614, Transcriptional regulator IclR, C-terminal, score 3.3e-51
550537002649	PS01051 Bacterial regulatory proteins, iclR family signature.
550537002650	glyoxylate carboligase; Provisional; Region: PRK11269
550537002651	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
550537002652	PYR/PP interface [polypeptide binding]; other site
550537002653	dimer interface [polypeptide binding]; other site
550537002654	TPP binding site [chemical binding]; other site
550537002655	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
550537002656	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
550537002657	TPP-binding site [chemical binding]; other site
550537002658	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding region, score 1.7e-53
550537002659	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central region, score 1.2e-51
550537002660	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding, score 4.2e-52
550537002661	hydroxypyruvate isomerase; Provisional; Region: PRK09997
550537002662	HMMPfam hit to PF01261, Xylose isomerase-type TIM barrel, score 8.5e-55
550537002663	PS00778 Histidine acid phosphatases active site signature.
550537002664	tartronate semialdehyde reductase; Provisional; Region: PRK15059
550537002665	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
550537002666	HMMPfam hit to PF03446, 6-phosphogluconate dehydrogenase, NAD-binding, score 1.7e-70
550537002667	PS00895 3-hydroxyisobutyrate dehydrogenase signature.
550537002668	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537002669	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537002670	putative substrate translocation pore; other site
550537002671	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.2e-50
550537002672	12 probable transmembrane helices predicted for SEN0501 by TMHMM2.0 at aa 20-37, 52-74, 81-98, 103-125, 138-160, 170-192, 220-242, 257-279, 292-310, 320-339, 352-374 and 384-403
550537002673	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002674	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
550537002675	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
550537002676	substrate binding site [chemical binding]; other site
550537002677	Na binding site [ion binding]; other site
550537002678	HMMPfam hit to PF02133, Permease for cytosine/purines, uracil, thiamine, allantoin, score 2.8e-163
550537002679	12 probable transmembrane helices predicted for SEN0503 by TMHMM2.0 at aa 7-29, 44-63, 70-92, 107-129, 142-164, 179-201, 221-243, 263-285, 298-320, 330-352, 373-392 and 402-421
550537002680	allantoinase; Provisional; Region: PRK08044
550537002681	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
550537002682	active site
550537002683	HMMPfam hit to PF01979, Amidohydrolase 1, score 4.2e-11
550537002684	putative uracil/xanthine transporter; Provisional; Region: PRK11412
550537002685	PS00430 TonB-dependent receptor proteins signature 1.
550537002686	HMMPfam hit to PF00860, Xanthine/uracil/vitamin C permease, score 2.7e-98
550537002687	11 probable transmembrane helices predicted for SEN0505 by TMHMM2.0 at aa 15-37, 42-64, 99-121, 128-150, 170-189, 196-213, 237-259, 280-302, 341-363, 375-397 and 407-426
550537002688	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002689	glycerate kinase II; Provisional; Region: PRK09932
550537002690	HMMPfam hit to PF02595, Glycerate kinase, score 1.2e-251
550537002691	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002692	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
550537002693	Mif2/CENP-C like; Region: Mif2; pfam11699
550537002694	Cupin domain; Region: Cupin_2; pfam07883
550537002695	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 8.7e-05
550537002696	HMMPfam hit to PF05899, Protein of unknown function DUF861, cupin-3, score 4.4e-15
550537002697	allantoate amidohydrolase; Region: AllC; TIGR03176
550537002698	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
550537002699	active site
550537002700	metal binding site [ion binding]; metal-binding site
550537002701	dimer interface [polypeptide binding]; other site
550537002702	HMMPfam hit to PF01546, Peptidase M20, score 7.6e-42
550537002703	HMMPfam hit to PF07687, Peptidase M20, dimerisation, score 0.0026
550537002704	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
550537002705	HMMPfam hit to PF02615, Malate/L-lactate dehydrogenase, score 4.8e-195
550537002706	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537002707	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002708	membrane protein FdrA; Validated; Region: PRK06091
550537002709	CoA binding domain; Region: CoA_binding; pfam02629
550537002710	CoA-ligase; Region: Ligase_CoA; pfam00549
550537002711	HMMPfam hit to PF06263, Bacterial FdrA, score 0
550537002712	PS00215 Mitochondrial energy transfer proteins signature.
550537002713	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
550537002714	HMMPfam hit to PF06545, Protein of unknown function DUF1116, score 0
550537002715	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
550537002716	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
550537002717	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
550537002718	putative substrate binding site [chemical binding]; other site
550537002719	nucleotide binding site [chemical binding]; other site
550537002720	nucleotide binding site [chemical binding]; other site
550537002721	homodimer interface [polypeptide binding]; other site
550537002722	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 5.9e-77
550537002723	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
550537002724	ATP-grasp domain; Region: ATP-grasp; pfam02222
550537002725	HMMPfam hit to PF02222, ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type, score 1.4e-91
550537002726	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
550537002727	HMMPfam hit to PF00731, 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase, score 1.4e-105
550537002728	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
550537002729	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
550537002730	putative active site [active]
550537002731	putative metal binding site [ion binding]; other site
550537002732	HMMPfam hit to PF00149, Metallophosphoesterase, score 2.5e-13
550537002733	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
550537002734	substrate binding site [chemical binding]; other site
550537002735	HMMPfam hit to PF00160, Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, score 4.5e-53
550537002736	PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
550537002737	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
550537002738	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
550537002739	active site
550537002740	HIGH motif; other site
550537002741	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
550537002742	KMSKS motif; other site
550537002743	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
550537002744	tRNA binding surface [nucleotide binding]; other site
550537002745	anticodon binding site; other site
550537002746	HMMPfam hit to PF01406, Cysteinyl-tRNA synthetase, class Ia, N-terminal, score 8.8e-222
550537002747	HMMPfam hit to PF09190, Cysteinyl-tRNA synthetase, class Ia, DALR, score 5.6e-34
550537002748	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
550537002749	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
550537002750	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
550537002751	4 probable transmembrane helices predicted for SEN0521 by TMHMM2.0 at aa 12-34, 54-76, 89-108 and 149-171
550537002752	HMMPfam hit to PF04307, Protein of unknown function DUF457, transmembrane, score 2.2e-34
550537002753	ribosome-associated protein; Provisional; Region: PRK11507
550537002754	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
550537002755	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
550537002756	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
550537002757	homodimer interface [polypeptide binding]; other site
550537002758	NADP binding site [chemical binding]; other site
550537002759	substrate binding site [chemical binding]; other site
550537002760	HMMPfam hit to PF02882, Tetrahydrofolate dehydrogenase/cyclohydrolase, score 9.7e-109
550537002761	PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2.
550537002762	HMMPfam hit to PF00763, Tetrahydrofolate dehydrogenase/cyclohydrolase, score 9.6e-72
550537002763	PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1.
550537002764	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002765	fimbrial operon fim
550537002766	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
550537002767	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 1.8e-67
550537002768	fimbrial protein FimI; Provisional; Region: PRK15200
550537002769	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 4.1e-29
550537002770	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
550537002771	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537002772	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537002773	1 probable transmembrane helix predicted for SEN0526 by TMHMM2.0 at aa 7-29
550537002774	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 5.4e-69
550537002775	PS00635 Gram-negative pili assembly chaperone signature.
550537002776	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 6.2e-30
550537002777	outer membrane usher protein FimD; Provisional; Region: PRK15198
550537002778	PapC N-terminal domain; Region: PapC_N; pfam13954
550537002779	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537002780	PapC C-terminal domain; Region: PapC_C; pfam13953
550537002781	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537002782	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537002783	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
550537002784	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
550537002785	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 5.8e-56
550537002786	transcriptional regulator FimZ; Provisional; Region: PRK09935
550537002787	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537002788	active site
550537002789	phosphorylation site [posttranslational modification]
550537002790	intermolecular recognition site; other site
550537002791	dimerization interface [polypeptide binding]; other site
550537002792	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537002793	DNA binding residues [nucleotide binding]
550537002794	dimerization interface [polypeptide binding]; other site
550537002795	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 7.5e-30
550537002796	PS00622 Bacterial regulatory proteins, luxR family signature.
550537002797	HMMPfam hit to PF00072, Response regulator receiver, score 2.5e-38
550537002798	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
550537002799	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
550537002800	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537002801	DNA binding residues [nucleotide binding]
550537002802	dimerization interface [polypeptide binding]; other site
550537002803	Salmonella Pathogenicity Island 16; SPI-16
550537002805	HMMPfam hit to PF00665, Integrase, catalytic core, score 1.1e-19
550537002806	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
550537002807	Transposase; Region: HTH_Tnp_1; pfam01527
550537002808	HMMPfam hit to PF01527, Transposase IS3/IS911, score 1.3e-10
550537002809	9 probable transmembrane helices predicted for SEN0535 by TMHMM2.0 at aa 13-32, 77-96, 108-130, 135-157, 201-223, 254-273, 280-302, 307-329 and 336-358
550537002810	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002811	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
550537002812	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
550537002813	Ligand binding site; other site
550537002814	Putative Catalytic site; other site
550537002815	DXD motif; other site
550537002816	2 probable transmembrane helices predicted for SEN0536 by TMHMM2.0 at aa 227-249 and 264-286
550537002817	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 1.3e-33
550537002818	Predicted membrane protein [Function unknown]; Region: COG2246
550537002819	GtrA-like protein; Region: GtrA; pfam04138
550537002820	HMMPfam hit to PF04138, GtrA-like protein, score 6.4e-32
550537002821	4 probable transmembrane helices predicted for SEN0537 by TMHMM2.0 at aa 12-31, 35-54, 67-84 and 94-116
550537002823	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 7.7e-34
550537002825	Cupin; Region: Cupin_6; pfam12852
550537002826	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
550537002827	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537002828	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537002829	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 4.4e-08
550537002830	PS00041 Bacterial regulatory proteins, araC family signature.
550537002831	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 7.7e-05
550537002832	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
550537002833	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537002834	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
550537002835	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 2.5e-53
550537002836	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002837	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
550537002838	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 2.9e-31
550537002839	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase dimerisation region, score 9.8e-37
550537002840	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537002841	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 1.1e-05
550537002842	Predicted membrane protein [Function unknown]; Region: COG3059
550537002843	HMMPfam hit to PF04224, Protein of unknown function DUF417, score 3.3e-108
550537002844	4 probable transmembrane helices predicted for SEN0542 by TMHMM2.0 at aa 13-32, 87-106, 113-135 and 164-183
550537002845	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
550537002846	phenylalanine transporter; Provisional; Region: PRK10249
550537002847	HMMPfam hit to PF00324, Amino acid permease-associated region, score 4.4e-147
550537002848	12 probable transmembrane helices predicted for SEN0544 by TMHMM2.0 at aa 34-53, 57-74, 107-129, 139-161, 166-188, 210-232, 253-275, 295-317, 344-366, 370-392, 413-435 and 440-459
550537002849	PS00218 Amino acid permeases signature.
550537002850	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
550537002851	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537002852	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 2.1e-61
550537002853	5 probable transmembrane helices predicted for SEN0545 by TMHMM2.0 at aa 21-43, 72-89, 102-124, 139-161 and 166-183
550537002854	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
550537002855	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
550537002856	active site
550537002857	oxyanion hole [active]
550537002858	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
550537002859	catalytic triad [active]
550537002860	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
550537002861	HMMPfam hit to PF00657, Lipolytic enzyme, G-D-S-L, score 2.3e-10
550537002862	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002863	HMMPfam hit to PF03797, Autotransporter beta-domain, score 1.2e-34
550537002864	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
550537002865	dimer interface [polypeptide binding]; other site
550537002866	FMN binding site [chemical binding]; other site
550537002867	HMMPfam hit to PF00881, Nitroreductase, score 1.6e-72
550537002868	hypothetical protein; Provisional; Region: PRK10250
550537002869	HMMPfam hit to PF04237, Protein of unknown function DUF419, score 9.3e-45
550537002870	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
550537002871	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537002872	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 2.1e-12
550537002873	PS01081 Bacterial regulatory proteins, tetR family signature.
550537002874	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
550537002875	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537002876	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.3e-10
550537002877	PS00041 Bacterial regulatory proteins, araC family signature.
550537002878	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 7.1e-10
550537002879	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
550537002880	HMMPfam hit to PF06643, Protein of unknown function DUF1158, score 2.5e-56
550537002881	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
550537002882	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
550537002883	HMMPfam hit to PF04107, Glutamate--cysteine ligase, GCS2, score 3e-115
550537002884	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
550537002885	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
550537002886	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase, score 1.3e-05
550537002887	outer membrane receptor FepA; Provisional; Region: PRK13524
550537002888	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537002889	N-terminal plug; other site
550537002890	ligand-binding site [chemical binding]; other site
550537002891	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 1.1e-29
550537002892	PS01156 TonB-dependent receptor proteins signature 2.
550537002893	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002894	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 1.4e-29
550537002895	PS00430 TonB-dependent receptor proteins signature 1.
550537002896	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
550537002897	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
550537002898	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
550537002899	HMMPfam hit to PF00756,  esterase, score 1.5e-61
550537002900	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
550537002901	HMMPfam hit to PF03621, MbtH-like protein, score 5.2e-30
550537002902	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
550537002903	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
550537002904	acyl-activating enzyme (AAE) consensus motif; other site
550537002905	AMP binding site [chemical binding]; other site
550537002906	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
550537002907	HMMPfam hit to PF00668, Condensation domain, score 1.4e-61
550537002908	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 2.1e-158
550537002909	PS00455  AMP-binding domain signature.
550537002910	HMMPfam hit to PF00550, Phosphopantetheine-binding, score 1e-09
550537002911	PS00012 Phosphopantetheine attachment site.
550537002912	HMMPfam hit to PF00975, Thioesterase, score 3.5e-49
550537002913	LPS O-antigen length regulator; Provisional; Region: PRK10381
550537002914	Chain length determinant protein; Region: Wzz; pfam02706
550537002915	HMMPfam hit to PF02706, Lipopolysaccharide biosynthesis, score 3.2e-22
550537002916	2 probable transmembrane helices predicted for SEN0558 by TMHMM2.0 at aa 43-62 and 338-360
550537002917	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002918	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
550537002919	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
550537002920	Walker A/P-loop; other site
550537002921	ATP binding site [chemical binding]; other site
550537002922	Q-loop/lid; other site
550537002923	ABC transporter signature motif; other site
550537002924	Walker B; other site
550537002925	D-loop; other site
550537002926	H-loop/switch region; other site
550537002927	HMMPfam hit to PF00005, ABC transporter related, score 1.8e-50
550537002928	PS00211 ABC transporters family signature.
550537002929	PS00017 ATP/GTP-binding site motif A (P-loop).
550537002930	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
550537002931	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537002932	ABC-ATPase subunit  interface; other site
550537002933	dimer interface [polypeptide binding]; other site
550537002934	putative PBP binding regions; other site
550537002935	HMMPfam hit to PF01032, Bacterial transport system permease protein, score 7.8e-130
550537002936	8 probable transmembrane helices predicted for SEN0560 by TMHMM2.0 at aa 7-26, 57-79, 92-111, 115-137, 144-166, 193-210, 239-261 and 301-323
550537002937	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002938	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
550537002939	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537002940	ABC-ATPase subunit  interface; other site
550537002941	dimer interface [polypeptide binding]; other site
550537002942	putative PBP binding regions; other site
550537002943	HMMPfam hit to PF01032, Bacterial transport system permease protein, score 4.3e-138
550537002944	9 probable transmembrane helices predicted for SEN0561 by TMHMM2.0 at aa 10-32, 65-82, 92-114, 121-140, 155-177, 198-220, 240-262, 282-304 and 308-326
550537002945	enterobactin exporter EntS; Provisional; Region: PRK10489
550537002946	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537002947	putative substrate translocation pore; other site
550537002948	12 probable transmembrane helices predicted for SEN0562 by TMHMM2.0 at aa 22-44, 54-76, 83-105, 110-132, 153-175, 179-201, 214-236, 256-278, 285-307, 312-331, 351-373 and 377-399
550537002949	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 6e-25
550537002950	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
550537002951	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
550537002952	siderophore binding site; other site
550537002953	HMMPfam hit to PF01497, Periplasmic binding protein, score 3.3e-51
550537002954	isochorismate synthase EntC; Provisional; Region: PRK15016
550537002955	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
550537002956	HMMPfam hit to PF00425, Chorismate binding, C-terminal, score 8.1e-108
550537002957	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
550537002958	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
550537002959	acyl-activating enzyme (AAE) consensus motif; other site
550537002960	active site
550537002961	AMP binding site [chemical binding]; other site
550537002962	substrate binding site [chemical binding]; other site
550537002963	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 3.1e-104
550537002964	PS00455  AMP-binding domain signature.
550537002965	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
550537002966	hydrophobic substrate binding pocket; other site
550537002967	Isochorismatase family; Region: Isochorismatase; pfam00857
550537002968	active site
550537002969	conserved cis-peptide bond; other site
550537002970	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
550537002971	HMMPfam hit to PF00857, Isochorismatase hydrolase, score 7.6e-102
550537002972	HMMPfam hit to PF00550, Phosphopantetheine-binding, score 2.3e-11
550537002973	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
550537002974	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
550537002975	putative NAD(P) binding site [chemical binding]; other site
550537002976	active site
550537002977	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 7.7e-26
550537002978	PS00061 Short-chain dehydrogenases/reductases family signature.
550537002979	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
550537002980	CoenzymeA binding site [chemical binding]; other site
550537002981	subunit interaction site [polypeptide binding]; other site
550537002982	PHB binding site; other site
550537002983	HMMPfam hit to PF03061, Thioesterase superfamily, score 3.4e-19
550537002984	carbon starvation protein A; Provisional; Region: PRK15015
550537002985	Carbon starvation protein CstA; Region: CstA; pfam02554
550537002986	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
550537002987	18 probable transmembrane helices predicted for SEN0569 by TMHMM2.0 at aa 7-26, 32-54, 89-111, 116-138, 159-181, 191-213, 218-240, 255-277, 284-306, 326-348, 361-383, 398-420, 441-463, 468-487, 514-533, 548-570, 577-599 and 649-671
550537002988	HMMPfam hit to PF02554, Carbon starvation protein CstA, score 2.2e-294
550537002989	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002990	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002991	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537002992	Uncharacterized small protein [Function unknown]; Region: COG2879
550537002993	HMMPfam hit to PF04328, Protein of unknown function DUF466, score 6.6e-45
550537002994	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
550537002995	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
550537002996	putative active site [active]
550537002997	metal binding site [ion binding]; metal-binding site
550537002998	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 3.5e-09
550537002999	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537003000	methionine aminotransferase; Validated; Region: PRK09082
550537003001	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537003002	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537003003	homodimer interface [polypeptide binding]; other site
550537003004	catalytic residue [active]
550537003005	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 6.2e-55
550537003006	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003007	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
550537003008	ParB-like nuclease domain; Region: ParBc; pfam02195
550537003009	HMMPfam hit to PF02195, ParB-like nuclease, score 4.1e-18
550537003010	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
550537003011	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
550537003012	Active Sites [active]
550537003013	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
550537003014	HMMPfam hit to PF01507, Phosphoadenosine phosphosulphate reductase, score 3.3e-07
550537003015	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
550537003016	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537003017	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537003018	dimerization interface [polypeptide binding]; other site
550537003019	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.5e-05
550537003020	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 8.6e-21
550537003021	PS00044 Bacterial regulatory proteins, lysR family signature.
550537003022	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
550537003023	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
550537003024	dimerization domain [polypeptide binding]; other site
550537003025	dimer interface [polypeptide binding]; other site
550537003026	catalytic residues [active]
550537003027	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
550537003028	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
550537003029	dimer interface [polypeptide binding]; other site
550537003030	decamer (pentamer of dimers) interface [polypeptide binding]; other site
550537003031	catalytic triad [active]
550537003032	peroxidatic and resolving cysteines [active]
550537003033	HMMPfam hit to PF00578, Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen, score 7.5e-40
550537003034	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
550537003035	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
550537003036	catalytic residue [active]
550537003037	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
550537003038	catalytic residues [active]
550537003039	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537003040	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537003041	HMMPfam hit to PF00462, Glutaredoxin, score 0.00094
550537003042	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 2.7e-45
550537003043	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
550537003044	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 4.9e-23
550537003045	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
550537003046	HMMPfam hit to PF06192, Cytoplasmic chaperone TorD, score 7.9e-56
550537003047	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
550537003048	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
550537003049	putative [4Fe-4S] binding site [ion binding]; other site
550537003050	putative molybdopterin cofactor binding site [chemical binding]; other site
550537003051	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
550537003052	molybdopterin cofactor binding site; other site
550537003053	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 4.9e-09
550537003054	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 4.9e-54
550537003055	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 7.1e-21
550537003056	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
550537003057	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
550537003058	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0019
550537003059	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 1.4e-07
550537003060	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537003061	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
550537003062	HMMPfam hit to PF04976, DMSO reductase anchor subunit (DmsC), score 6.3e-12
550537003063	8 probable transmembrane helices predicted for SEN0582 by TMHMM2.0 at aa 5-27, 39-61, 76-95, 102-124, 134-156, 163-185, 195-217 and 224-241
550537003064	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003065	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
550537003066	Ligand Binding Site [chemical binding]; other site
550537003067	HMMPfam hit to PF00582, UspA, score 5.9e-16
550537003068	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
550537003069	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
550537003070	NAD binding site [chemical binding]; other site
550537003071	catalytic Zn binding site [ion binding]; other site
550537003072	structural Zn binding site [ion binding]; other site
550537003073	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 1.8e-48
550537003074	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537003075	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 7.5e-24
550537003076	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003077	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
550537003078	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
550537003079	HMMPfam hit to PF01272, Transcription elongation factor, GreA/GreB region, prokaryotic, score 0.0035
550537003080	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
550537003081	B1 nucleotide binding pocket [chemical binding]; other site
550537003082	B2 nucleotide binding pocket [chemical binding]; other site
550537003083	CAS motifs; other site
550537003084	active site
550537003085	PS00531 Ribonuclease T2 family histidine active site 2.
550537003086	PS00530 Ribonuclease T2 family histidine active site 1.
550537003087	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
550537003088	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
550537003089	transmembrane helices; other site
550537003090	HMMPfam hit to PF00939, Sodium/sulphate symporter, score 9.7e-288
550537003091	13 probable transmembrane helices predicted for SEN0587 by TMHMM2.0 at aa 7-24, 34-53, 58-75, 95-117, 138-157, 198-220, 233-255, 288-305, 307-329, 339-361, 374-396, 428-450 and 463-485
550537003092	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003093	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003094	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
550537003095	HMMPfam hit to PF01874, Triphosphoribosyl-dephospho-CoA protein, score 5e-125
550537003096	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
550537003097	HMMPfam hit to PF03802, Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, score 2.7e-84
550537003098	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003099	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
550537003100	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
550537003101	HMMPfam hit to PF04223, Citrate lyase, alpha subunit, score 0
550537003102	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537003103	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
550537003104	HMMPfam hit to PF03328, HpcH/HpaI aldolase, score 1.8e-117
550537003105	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
550537003106	HMMPfam hit to PF04953, Citrate lyase acyl carrier protein CitD, score 3.6e-62
550537003107	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
550537003108	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
550537003109	putative active site [active]
550537003110	(T/H)XGH motif; other site
550537003111	HMMPfam hit to PF08218, Citrate lyase ligase, C-terminal, score 3.5e-123
550537003112	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 6.1e-05
550537003113	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
550537003114	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537003115	putative active site [active]
550537003116	heme pocket [chemical binding]; other site
550537003117	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537003118	ATP binding site [chemical binding]; other site
550537003119	Mg2+ binding site [ion binding]; other site
550537003120	G-X-G motif; other site
550537003121	2 probable transmembrane helices predicted for SEN0594 by TMHMM2.0 at aa 20-42 and 180-202
550537003122	HMMPfam hit to PF00989, PAS fold, score 9.3e-06
550537003123	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 8.3e-27
550537003124	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
550537003125	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537003126	active site
550537003127	phosphorylation site [posttranslational modification]
550537003128	intermolecular recognition site; other site
550537003129	dimerization interface [polypeptide binding]; other site
550537003130	Transcriptional regulator; Region: CitT; pfam12431
550537003131	HMMPfam hit to PF00072, Response regulator receiver, score 7.7e-24
550537003132	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
550537003133	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
550537003134	10 probable transmembrane helices predicted for SEN0596 by TMHMM2.0 at aa 37-59, 80-102, 117-139, 152-174, 194-216, 223-245, 265-287, 299-321, 363-385 and 392-414
550537003135	HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 2.3e-173
550537003136	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
550537003137	1 probable transmembrane helix predicted for SEN0597 by TMHMM2.0 at aa 7-29
550537003138	HMMPfam hit to PF07017, Antimicrobial peptide resistance and lipid A acylation PagP, score 4.1e-118
550537003139	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
550537003140	DNA-binding site [nucleotide binding]; DNA binding site
550537003141	RNA-binding motif; other site
550537003142	HMMPfam hit to PF00313, Cold-shock protein, DNA-binding, score 2e-44
550537003143	PS00352 'Cold-shock' DNA-binding domain signature.
550537003144	chromosome condensation membrane protein; Provisional; Region: PRK14196
550537003145	4 probable transmembrane helices predicted for SEN0599 by TMHMM2.0 at aa 5-22, 32-54, 67-89 and 99-121
550537003146	HMMPfam hit to PF02537, Camphor resistance CrcB protein, score 1.6e-58
550537003147	Predicted amidohydrolase [General function prediction only]; Region: COG0388
550537003148	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
550537003149	putative active site [active]
550537003150	catalytic triad [active]
550537003151	putative dimer interface [polypeptide binding]; other site
550537003152	HMMPfam hit to PF00795, Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, score 4.9e-23
550537003153	PS01227 Uncharacterized protein family UPF0012 signature.
550537003154	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
550537003155	HMMPfam hit to PF02416, Bacterial sec-independent translocation protein mttA/Hcf106, score 1.7e-08
550537003156	1 probable transmembrane helix predicted for SEN0601 by TMHMM2.0 at aa 4-21
550537003157	lipoyl synthase; Provisional; Region: PRK05481
550537003158	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537003159	FeS/SAM binding site; other site
550537003160	HMMPfam hit to PF04055, Radical SAM, score 4.6e-23
550537003161	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
550537003162	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537003163	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
550537003164	substrate binding pocket [chemical binding]; other site
550537003165	dimerization interface [polypeptide binding]; other site
550537003166	HMMPfam hit to PF03466, LysR, substrate-binding, score 9.5e-11
550537003167	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 7.8e-16
550537003168	PS00044 Bacterial regulatory proteins, lysR family signature.
550537003169	lipoate-protein ligase B; Provisional; Region: PRK14342
550537003170	PS00092 N-6 Adenine-specific DNA methylases signature.
550537003171	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase, score 8.1e-18
550537003172	PS01313 Lipoate-protein ligase B signature.
550537003173	hypothetical protein; Provisional; Region: PRK04998
550537003174	HMMPfam hit to PF04359, Protein of unknown function DUF493, score 3.6e-54
550537003175	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
550537003176	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
550537003177	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
550537003178	HMMPfam hit to PF07943, Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal, score 2.4e-37
550537003179	HMMPfam hit to PF00768, Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, score 7.8e-153
550537003180	rare lipoprotein A; Provisional; Region: PRK10672
550537003181	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
550537003182	Sporulation related domain; Region: SPOR; pfam05036
550537003183	HMMPfam hit to PF05036, Sporulation/cell division region, bacteria, score 3.8e-19
550537003184	HMMPfam hit to PF03330, Rare lipoprotein A, score 4e-27
550537003185	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003186	cell wall shape-determining protein; Provisional; Region: PRK10794
550537003187	HMMPfam hit to PF01098, Cell cycle protein, score 1.8e-183
550537003188	9 probable transmembrane helices predicted for SEN0608 by TMHMM2.0 at aa 15-37, 50-67, 77-99, 136-155, 160-179, 181-203, 272-294, 306-328 and 338-360
550537003189	PS00428 Cell cycle proteins ftsW / rodA / spoVE signature.
550537003190	penicillin-binding protein 2; Provisional; Region: PRK10795
550537003191	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
550537003192	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
550537003193	HMMPfam hit to PF00905, Penicillin-binding protein, transpeptidase, score 2.5e-103
550537003194	HMMPfam hit to PF03717, Penicillin-binding protein, dimerisation domain, score 4.2e-68
550537003195	1 probable transmembrane helix predicted for SEN0609 by TMHMM2.0 at aa 21-43
550537003196	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
550537003197	HMMPfam hit to PF02590, Protein of unknown function DUF163, score 7.3e-113
550537003198	ribosome-associated protein; Provisional; Region: PRK11538
550537003199	HMMPfam hit to PF02410, Iojap-related protein, score 1.3e-53
550537003200	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003201	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
550537003202	catalytic core [active]
550537003203	HMMPfam hit to PF00300, Phosphoglycerate mutase, score 3.6e-48
550537003204	PS00175 Phosphoglycerate mutase family phosphohistidine signature.
550537003205	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
550537003206	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537003207	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537003208	homodimer interface [polypeptide binding]; other site
550537003209	catalytic residue [active]
550537003210	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 7.2e-36
550537003211	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
550537003212	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
550537003213	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
550537003214	active site
550537003215	(T/H)XGH motif; other site
550537003216	HMMPfam hit to PF01467, Cytidylyltransferase, score 1.4e-61
550537003217	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
550537003218	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
550537003219	HMMPfam hit to PF06144, DNA polymerase III, delta, score 2.3e-129
550537003220	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
550537003221	HMMPfam hit to PF04390, Rare lipoprotein B, score 1e-78
550537003222	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003223	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
550537003224	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
550537003225	HIGH motif; other site
550537003226	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
550537003227	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
550537003228	active site
550537003229	KMSKS motif; other site
550537003230	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
550537003231	tRNA binding surface [nucleotide binding]; other site
550537003232	HMMPfam hit to PF08264, Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding, score 2.1e-07
550537003233	HMMPfam hit to PF00133, Aminoacyl-tRNA synthetase, class Ia, score 1.7e-13
550537003234	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537003235	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
550537003236	HMMPfam hit to PF08666, SAF domain, score 6.8e-08
550537003237	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
550537003238	HMMPfam hit to PF04295, D-galactarate dehydratase/Altronate hydrolase, C-terminal, score 1.6e-155
550537003239	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003240	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
550537003241	HMMPfam hit to PF03812, 2-keto-3-deoxygluconate permease, score 2e-80
550537003242	8 probable transmembrane helices predicted for SEN0620 by TMHMM2.0 at aa 7-25, 35-57, 70-92, 157-179, 192-211, 216-238, 247-269 and 279-301
550537003243	Propionate catabolism activator; Region: PrpR_N; pfam06506
550537003244	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
550537003245	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537003246	Walker A motif; other site
550537003247	ATP binding site [chemical binding]; other site
550537003248	Walker B motif; other site
550537003249	arginine finger; other site
550537003250	HMMPfam hit to PF06506, Propionate catabolism activator, N-terminal, score 1.9e-07
550537003251	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 1.3e-129
550537003252	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537003253	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537003254	hypothetical protein; Provisional; Region: PRK11032
550537003255	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
550537003256	HMMPfam hit to PF07295, Protein of unknown function DUF1451, score 3.4e-101
550537003257	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537003258	Sel1-like repeats; Region: SEL1; smart00671
550537003259	Sel1-like repeats; Region: SEL1; smart00671
550537003260	Sel1-like repeats; Region: SEL1; smart00671
550537003261	Sel1-like repeats; Region: SEL1; smart00671
550537003262	Sel1-like repeats; Region: SEL1; smart00671
550537003263	HMMPfam hit to PF08238, Sel1-like, score 8.7e-06
550537003264	HMMPfam hit to PF08238, Sel1-like, score 2.2e-06
550537003265	HMMPfam hit to PF08238, Sel1-like, score 2.4e-13
550537003266	HMMPfam hit to PF08238, Sel1-like, score 1.2e-06
550537003267	HMMPfam hit to PF08238, Sel1-like, score 2.2e-12
550537003268	HMMPfam hit to PF08238, Sel1-like, score 6.3e-05
550537003269	HMMPfam hit to PF08238, Sel1-like, score 0.00034
550537003270	HMMPfam hit to PF08238, Sel1-like, score 0.00019
550537003271	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
550537003272	HMMPfam hit to PF06889, Protein of unknown function DUF1266, score 5.6e-199
550537003273	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
550537003274	HSP70 interaction site [polypeptide binding]; other site
550537003275	HMMPfam hit to PF00226, Heat shock protein DnaJ, N-terminal, score 5e-07
550537003276	1 probable transmembrane helix predicted for SEN0625 by TMHMM2.0 at aa 453-472
550537003277	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
550537003278	HMMPfam hit to PF06889, Protein of unknown function DUF1266, score 2.5e-194
550537003279	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
550537003280	HSP70 interaction site [polypeptide binding]; other site
550537003281	HMMPfam hit to PF00226, Heat shock protein DnaJ, N-terminal, score 0.0017
550537003282	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
550537003283	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
550537003284	nucleotide binding site [chemical binding]; other site
550537003285	putative NEF/HSP70 interaction site [polypeptide binding]; other site
550537003286	SBD interface [polypeptide binding]; other site
550537003287	HMMPfam hit to PF00012, Heat shock protein 70, score 2.9e-98
550537003288	PS01036 Heat shock hsp70 proteins family signature 3.
550537003289	PS00329 Heat shock hsp70 proteins family signature 2.
550537003290	PS00297 Heat shock hsp70 proteins family signature 1.
550537003291	Note the premature stop codon following codon 171
550537003292	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
550537003293	active site
550537003294	tetramer interface [polypeptide binding]; other site
550537003295	HMMPfam hit to PF01156, Inosine/uridine-preferring nucleoside hydrolase, score 2.6e-181
550537003296	PS01247 Inosine-uridine preferring nucleoside hydrolase family signature.
550537003297	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
550537003298	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
550537003299	Walker A/P-loop; other site
550537003300	ATP binding site [chemical binding]; other site
550537003301	Q-loop/lid; other site
550537003302	ABC transporter signature motif; other site
550537003303	Walker B; other site
550537003304	D-loop; other site
550537003305	H-loop/switch region; other site
550537003306	HMMPfam hit to PF00005, ABC transporter related, score 8.3e-66
550537003307	PS00211 ABC transporters family signature.
550537003308	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003309	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537003310	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537003311	dimer interface [polypeptide binding]; other site
550537003312	conserved gate region; other site
550537003313	putative PBP binding loops; other site
550537003314	ABC-ATPase subunit interface; other site
550537003315	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.1e-30
550537003316	5 probable transmembrane helices predicted for SEN0632 by TMHMM2.0 at aa 15-37, 58-80, 95-112, 155-177 and 197-219
550537003317	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537003318	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537003319	dimer interface [polypeptide binding]; other site
550537003320	conserved gate region; other site
550537003321	putative PBP binding loops; other site
550537003322	ABC-ATPase subunit interface; other site
550537003323	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.3e-38
550537003324	5 probable transmembrane helices predicted for SEN0633 by TMHMM2.0 at aa 31-53, 66-88, 108-127, 179-196 and 211-233
550537003325	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
550537003326	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537003327	substrate binding pocket [chemical binding]; other site
550537003328	membrane-bound complex binding site; other site
550537003329	hinge residues; other site
550537003330	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 4.5e-56
550537003331	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
550537003332	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
550537003333	putative active site [active]
550537003334	catalytic triad [active]
550537003335	putative dimer interface [polypeptide binding]; other site
550537003336	8 probable transmembrane helices predicted for SEN0635 by TMHMM2.0 at aa 12-29, 33-50, 57-79, 89-111, 124-146, 166-188, 195-213 and 489-507
550537003337	HMMPfam hit to PF00795, Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, score 1.7e-51
550537003338	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
550537003339	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
550537003340	Transporter associated domain; Region: CorC_HlyC; smart01091
550537003341	HMMPfam hit to PF03471, Transporter-associated region, score 1.7e-29
550537003342	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 6.4e-28
550537003343	metal-binding heat shock protein; Provisional; Region: PRK00016
550537003344	HMMPfam hit to PF02130, Protein of unknown function UPF0054, score 2.9e-53
550537003345	PS01306 Uncharacterized protein family UPF0054 signature.
550537003346	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
550537003347	PhoH-like protein; Region: PhoH; pfam02562
550537003348	HMMPfam hit to PF02562, PhoH-like protein, score 6.3e-154
550537003349	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003350	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
550537003351	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
550537003352	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537003353	FeS/SAM binding site; other site
550537003354	TRAM domain; Region: TRAM; pfam01938
550537003355	HMMPfam hit to PF01938, Deoxyribonuclease/rho motif-related TRAM, score 2.1e-26
550537003356	HMMPfam hit to PF04055, Radical SAM, score 8.4e-34
550537003357	PS01278 Uncharacterized protein family UPF0004 signature.
550537003358	HMMPfam hit to PF00919, Protein of unknown function UPF0004, N-terminal, score 5.3e-51
550537003359	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
550537003360	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
550537003361	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 8.6e-07
550537003362	1 probable transmembrane helix predicted for SEN0640 by TMHMM2.0 at aa 7-29
550537003363	PS01304 ubiH/COQ6 monooxygenase family signature.
550537003364	4 probable transmembrane helices predicted for SEN0641 by TMHMM2.0 at aa 7-28, 33-55, 99-121 and 131-153
550537003365	asparagine synthetase B; Provisional; Region: asnB; PRK09431
550537003366	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
550537003367	active site
550537003368	dimer interface [polypeptide binding]; other site
550537003369	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
550537003370	Ligand Binding Site [chemical binding]; other site
550537003371	Molecular Tunnel; other site
550537003372	HMMPfam hit to PF00733, Asparagine synthase, score 5.7e-111
550537003373	HMMPfam hit to PF00310, Glutamine amidotransferase, class-II, score 1.2e-24
550537003374	PS00443 Glutamine amidotransferases class-II active site.
550537003375	UMP phosphatase; Provisional; Region: PRK10444
550537003376	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537003377	active site
550537003378	motif I; other site
550537003379	motif II; other site
550537003380	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537003381	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 2.5e-17
550537003382	MarR family; Region: MarR; pfam01047
550537003383	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
550537003384	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537003385	nucleotide binding site [chemical binding]; other site
550537003386	HMMPfam hit to PF00480, ROK, score 2.4e-84
550537003387	PS01125 ROK family signature.
550537003388	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 2.5e-07
550537003389	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
550537003390	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
550537003391	active site
550537003392	dimer interface [polypeptide binding]; other site
550537003393	HMMPfam hit to PF01979, Amidohydrolase 1, score 4.2e-56
550537003394	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
550537003395	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
550537003396	active site
550537003397	trimer interface [polypeptide binding]; other site
550537003398	allosteric site; other site
550537003399	active site lid [active]
550537003400	hexamer (dimer of trimers) interface [polypeptide binding]; other site
550537003401	HMMPfam hit to PF01182, Glucosamine/galactosamine-6-phosphate isomerase, score 3.3e-194
550537003402	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003403	PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature.
550537003404	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
550537003405	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
550537003406	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
550537003407	active site turn [active]
550537003408	phosphorylation site [posttranslational modification]
550537003409	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
550537003410	HPr interaction site; other site
550537003411	glycerol kinase (GK) interaction site [polypeptide binding]; other site
550537003412	active site
550537003413	phosphorylation site [posttranslational modification]
550537003414	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 6.7e-102
550537003415	11 probable transmembrane helices predicted for SEN0649 by TMHMM2.0 at aa 13-30, 40-62, 69-91, 96-118, 131-153, 163-185, 192-214, 229-251, 258-280, 295-317 and 337-359
550537003416	HMMPfam hit to PF00367, Phosphotransferase system, EIIB, score 6.2e-17
550537003417	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
550537003418	HMMPfam hit to PF00358, Phosphotransferase system, sugar-specific permease EIIA 1 domain, score 1.3e-82
550537003419	PS00371 PTS EIIA domains phosphorylation site signature 1.
550537003420	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
550537003421	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
550537003422	active site
550537003423	HIGH motif; other site
550537003424	nucleotide binding site [chemical binding]; other site
550537003425	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
550537003426	KMSKS motif; other site
550537003427	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
550537003428	HMMPfam hit to PF00749, Glutamyl/glutaminyl-tRNA synthetase, class Ic, score 8.2e-187
550537003429	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537003430	HMMPfam hit to PF03950, Glutamyl/glutaminyl-tRNA synthetase, class Ic, score 3.6e-108
550537003431	outer membrane porin, OprD family; Region: OprD; pfam03573
550537003432	HMMPfam hit to PF03573, Outer membrane porin, bacterial, score 2.1e-06
550537003433	1 probable transmembrane helix predicted for SEN0651 by TMHMM2.0 at aa 9-28
550537003434	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
550537003435	YbfN-like lipoprotein; Region: YbfN; pfam13982
550537003436	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003437	citrate-proton symporter; Provisional; Region: PRK15075
550537003438	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537003439	putative substrate translocation pore; other site
550537003440	12 probable transmembrane helices predicted for SEN0653 by TMHMM2.0 at aa 20-42, 57-79, 88-110, 120-142, 163-185, 189-211, 239-261, 276-298, 305-327, 337-356, 369-391 and 401-423
550537003441	HMMPfam hit to PF00083, General substrate transporter, score 3.2e-83
550537003442	PS00216 Sugar transport proteins signature 1.
550537003443	PS00217 Sugar transport proteins signature 2.
550537003444	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003445	PS00216 Sugar transport proteins signature 1.
550537003446	tricarballylate utilization protein B; Provisional; Region: PRK15033
550537003447	6 probable transmembrane helices predicted for SEN0654 by TMHMM2.0 at aa 112-134, 154-176, 230-252, 262-284, 305-322 and 327-349
550537003448	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0023
550537003449	tricarballylate dehydrogenase; Validated; Region: PRK08274
550537003450	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537003451	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6.8e-09
550537003452	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537003453	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537003454	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
550537003455	putative dimerization interface [polypeptide binding]; other site
550537003456	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.6e-37
550537003457	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 8.8e-17
550537003458	ferric uptake regulator; Provisional; Region: fur; PRK09462
550537003459	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
550537003460	metal binding site 2 [ion binding]; metal-binding site
550537003461	putative DNA binding helix; other site
550537003462	metal binding site 1 [ion binding]; metal-binding site
550537003463	dimer interface [polypeptide binding]; other site
550537003464	structural Zn2+ binding site [ion binding]; other site
550537003465	HMMPfam hit to PF01475, Ferric-uptake regulator, score 3.2e-74
550537003466	flavodoxin FldA; Validated; Region: PRK09267
550537003467	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 8.9e-55
550537003468	PS00201 Flavodoxin signature.
550537003469	LexA regulated protein; Provisional; Region: PRK11675
550537003470	HMMPfam hit to PF01402, CopG-like DNA-binding, score 6.4e-07
550537003471	acyl-CoA esterase; Provisional; Region: PRK10673
550537003472	PGAP1-like protein; Region: PGAP1; pfam07819
550537003473	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 5e-17
550537003474	replication initiation regulator SeqA; Provisional; Region: PRK11187
550537003475	HMMPfam hit to PF03925, SeqA protein, score 1.4e-133
550537003476	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
550537003477	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
550537003478	active site
550537003479	substrate binding site [chemical binding]; other site
550537003480	metal binding site [ion binding]; metal-binding site
550537003481	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, score 5e-43
550537003482	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
550537003483	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II, score 8.7e-18
550537003484	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III, score 8.4e-29
550537003485	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase C-terminal, score 9e-15
550537003486	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
550537003487	putrescine transporter; Provisional; Region: potE; PRK10655
550537003488	HMMPfam hit to PF00324, Amino acid permease-associated region, score 1.7e-05
550537003489	12 probable transmembrane helices predicted for SEN0664 by TMHMM2.0 at aa 9-31, 37-59, 89-111, 121-143, 150-172, 187-206, 227-249, 269-291, 325-342, 352-374, 387-405 and 410-429
550537003490	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003491	ornithine decarboxylase; Provisional; Region: PRK13578
550537003492	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
550537003493	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
550537003494	homodimer interface [polypeptide binding]; other site
550537003495	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537003496	catalytic residue [active]
550537003497	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
550537003498	HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal, score 3.4e-87
550537003499	HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major region, score 0
550537003500	PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site.
550537003501	HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal, score 1.6e-46
550537003502	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
550537003503	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537003504	active site
550537003505	phosphorylation site [posttranslational modification]
550537003506	intermolecular recognition site; other site
550537003507	dimerization interface [polypeptide binding]; other site
550537003508	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537003509	DNA binding site [nucleotide binding]
550537003510	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 1.7e-18
550537003511	HMMPfam hit to PF00072, Response regulator receiver, score 4.1e-46
550537003512	sensor protein KdpD; Provisional; Region: PRK10490
550537003513	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
550537003514	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
550537003515	Ligand Binding Site [chemical binding]; other site
550537003516	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
550537003517	GAF domain; Region: GAF_3; pfam13492
550537003518	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537003519	dimer interface [polypeptide binding]; other site
550537003520	phosphorylation site [posttranslational modification]
550537003521	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537003522	ATP binding site [chemical binding]; other site
550537003523	Mg2+ binding site [ion binding]; other site
550537003524	G-X-G motif; other site
550537003525	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1e-36
550537003526	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 9.1e-16
550537003527	3 probable transmembrane helices predicted for SEN0667 by TMHMM2.0 at aa 399-421, 428-450 and 476-498
550537003528	HMMPfam hit to PF00582, UspA, score 1.2e-09
550537003529	HMMPfam hit to PF02702, Osmosensitive K+ channel His kinase sensor, N-terminal, score 5e-155
550537003530	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003531	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
550537003532	HMMPfam hit to PF02669, K+ transporting ATPase, KdpC subunit, score 1.3e-112
550537003533	1 probable transmembrane helix predicted for SEN0668 by TMHMM2.0 at aa 12-34
550537003534	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
550537003535	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
550537003536	7 probable transmembrane helices predicted for SEN0669 by TMHMM2.0 at aa 37-59, 63-85, 220-242, 252-274, 578-600, 615-634 and 654-676
550537003537	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 2.4e-35
550537003538	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537003539	PS00154 E1-E2 ATPases phosphorylation site.
550537003540	HMMPfam hit to PF00122, E1-E2 ATPase-associated region, score 3.6e-66
550537003541	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
550537003542	HMMPfam hit to PF03814, K+ transporting ATPase, A subunit, score 0
550537003543	12 probable transmembrane helices predicted for SEN0670 by TMHMM2.0 at aa 5-27, 62-84, 130-152, 173-195, 253-275, 282-301, 325-347, 354-376, 380-399, 419-438, 483-505 and 526-548
550537003544	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003545	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
550537003546	1 probable transmembrane helix predicted for SEN0671 by TMHMM2.0 at aa 11-33
550537003547	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
550537003548	DNA photolyase; Region: DNA_photolyase; pfam00875
550537003549	HMMPfam hit to PF00875, DNA photolyase, N-terminal, score 1.1e-80
550537003550	HMMPfam hit to PF03441, DNA photolyase, FAD-binding, score 7.5e-159
550537003551	PS00394 DNA photolyases class 1 signature 1.
550537003552	PS00691 DNA photolyases class 1 signature 2.
550537003553	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
550537003554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537003555	putative substrate translocation pore; other site
550537003556	POT family; Region: PTR2; pfam00854
550537003557	14 probable transmembrane helices predicted for SEN0673 by TMHMM2.0 at aa 13-35, 50-67, 72-94, 98-117, 138-157, 167-189, 209-231, 235-254, 267-284, 310-332, 344-366, 376-398, 410-432 and 462-479
550537003558	HMMPfam hit to PF00854, TGF-beta receptor, type I/II extracellular region, score 9.3e-101
550537003559	PS01023 PTR2 family proton/oligopeptide symporters signature 2.
550537003560	PS01022 PTR2 family proton/oligopeptide symporters signature 1.
550537003561	Uncharacterized conserved protein [Function unknown]; Region: COG0327
550537003562	metal-binding protein; Provisional; Region: PRK10799
550537003563	HMMPfam hit to PF01784, NGG1p interacting factor 3, NIF3, score 2.5e-117
550537003564	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
550537003565	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
550537003566	HMMPfam hit to PF02682, Allophanate hydrolase subunit 1, score 3.8e-133
550537003567	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
550537003568	HMMPfam hit to PF02626, Allophanate hydrolase subunit 2, score 3.3e-171
550537003569	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
550537003570	putative active site [active]
550537003571	HMMPfam hit to PF03746, LamB/YcsF, score 2.7e-143
550537003572	endonuclease VIII; Provisional; Region: PRK10445
550537003573	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
550537003574	DNA binding site [nucleotide binding]
550537003575	catalytic residue [active]
550537003576	putative catalytic residues [active]
550537003577	H2TH interface [polypeptide binding]; other site
550537003578	intercalation triad [nucleotide binding]; other site
550537003579	substrate specificity determining residue; other site
550537003580	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
550537003581	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
550537003582	HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase, catalytic, score 4.4e-16
550537003583	HMMPfam hit to PF06831, Formamidopyrimidine-DNA glycolase, H2TH DNA binding, score 4.2e-33
550537003584	HMMPfam hit to PF06827, Formamidopyrimidine-DNA glycolase, C-terminal, score 0.0015
550537003585	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
550537003586	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
550537003587	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
550537003588	HMMPfam hit to PF05145,  ammonia monooxygenase, score 4.5e-130
550537003589	6 probable transmembrane helices predicted for SEN0679 by TMHMM2.0 at aa 21-43, 53-75, 116-135, 145-167, 234-256 and 289-311
550537003590	PS00099 Thiolases active site.
550537003591	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003592	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
550537003593	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
550537003594	dimer interface [polypeptide binding]; other site
550537003595	active site
550537003596	citrylCoA binding site [chemical binding]; other site
550537003597	NADH binding [chemical binding]; other site
550537003598	cationic pore residues; other site
550537003599	oxalacetate/citrate binding site [chemical binding]; other site
550537003600	coenzyme A binding site [chemical binding]; other site
550537003601	catalytic triad [active]
550537003602	HMMPfam hit to PF00285, Citrate synthase, score 3.1e-234
550537003603	PS00480 Citrate synthase signature.
550537003604	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
550537003605	Iron-sulfur protein interface; other site
550537003606	proximal quinone binding site [chemical binding]; other site
550537003607	SdhD (CybS) interface [polypeptide binding]; other site
550537003608	proximal heme binding site [chemical binding]; other site
550537003609	HMMPfam hit to PF01127, Succinate dehydrogenase, cytochrome b subunit, score 1.6e-42
550537003610	PS01000 Succinate dehydrogenase cytochrome b subunit signature 1.
550537003611	3 probable transmembrane helices predicted for SEN0682 by TMHMM2.0 at aa 27-49, 69-88 and 109-128
550537003612	PS01001 Succinate dehydrogenase cytochrome b subunit signature 2.
550537003613	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
550537003614	SdhC subunit interface [polypeptide binding]; other site
550537003615	proximal heme binding site [chemical binding]; other site
550537003616	cardiolipin binding site; other site
550537003617	Iron-sulfur protein interface; other site
550537003618	proximal quinone binding site [chemical binding]; other site
550537003619	3 probable transmembrane helices predicted for SEN0683 by TMHMM2.0 at aa 16-38, 48-70 and 91-113
550537003620	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
550537003621	L-aspartate oxidase; Provisional; Region: PRK06175
550537003622	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
550537003623	HMMPfam hit to PF00890, Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal, score 2.6e-172
550537003624	PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site.
550537003625	HMMPfam hit to PF02910, Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal, score 1.7e-68
550537003626	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
550537003627	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
550537003628	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537003629	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
550537003630	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
550537003631	TPP-binding site [chemical binding]; other site
550537003632	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
550537003633	dimer interface [polypeptide binding]; other site
550537003634	PYR/PP interface [polypeptide binding]; other site
550537003635	TPP binding site [chemical binding]; other site
550537003636	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537003637	HMMPfam hit to PF00676, Dehydrogenase, E1 component, score 6.3e-31
550537003638	HMMPfam hit to PF02779, Transketolase, central region, score 8.8e-75
550537003639	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
550537003640	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
550537003641	E3 interaction surface; other site
550537003642	lipoyl attachment site [posttranslational modification]; other site
550537003643	e3 binding domain; Region: E3_binding; pfam02817
550537003644	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
550537003645	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 1.9e-21
550537003646	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
550537003647	HMMPfam hit to PF02817, E3 binding, score 1.2e-16
550537003648	HMMPfam hit to PF00198, Catalytic domain of components of various dehydrogenase complexes, score 3.5e-142
550537003649	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
550537003650	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
550537003651	CoA-ligase; Region: Ligase_CoA; pfam00549
550537003652	HMMPfam hit to PF08442, ATP-grasp fold, succinyl-CoA synthetase-type, score 3e-146
550537003653	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003654	HMMPfam hit to PF00549, ATP-citrate lyase/succinyl-CoA ligase, score 2.4e-81
550537003655	PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3.
550537003656	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
550537003657	CoA binding domain; Region: CoA_binding; smart00881
550537003658	CoA-ligase; Region: Ligase_CoA; pfam00549
550537003659	HMMPfam hit to PF02629, CoA-binding, score 8.3e-52
550537003660	HMMPfam hit to PF00549, ATP-citrate lyase/succinyl-CoA ligase, score 2.2e-65
550537003661	PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1.
550537003662	PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site.
550537003663	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
550537003664	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
550537003665	HMMPfam hit to PF01654, Cytochrome bd ubiquinol oxidase, subunit I, score 0
550537003666	9 probable transmembrane helices predicted for SEN0690 by TMHMM2.0 at aa 20-42, 54-76, 96-118, 130-152, 184-206, 219-238, 387-409, 421-443 and 472-494
550537003667	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
550537003668	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
550537003669	HMMPfam hit to PF02322, Cytochrome bd ubiquinol oxidase, subunit II, score 6.2e-227
550537003670	8 probable transmembrane helices predicted for SEN0691 by TMHMM2.0 at aa 7-24, 77-99, 122-144, 159-181, 202-224, 262-281, 293-315 and 335-357
550537003671	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003672	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
550537003673	HMMPfam hit to PF08173, Membrane bound YbgT-like, score 4.9e-14
550537003674	1 probable transmembrane helix predicted for SEN0692 by TMHMM2.0 at aa 2-24
550537003675	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003676	hypothetical protein; Provisional; Region: PRK10588
550537003677	3 probable transmembrane helices predicted for SEN0693 by TMHMM2.0 at aa 5-23, 35-57 and 62-84
550537003678	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003679	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
550537003680	active site
550537003681	PS01328 4-hydroxybenzoyl-CoA thioesterase family active site.
550537003682	HMMPfam hit to PF03061, Thioesterase superfamily, score 6.7e-18
550537003683	colicin uptake protein TolQ; Provisional; Region: PRK10801
550537003684	3 probable transmembrane helices predicted for SEN0695 by TMHMM2.0 at aa 15-37, 133-155 and 170-192
550537003685	HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel, score 5.9e-64
550537003686	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
550537003687	colicin uptake protein TolR; Provisional; Region: PRK11024
550537003688	HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 1.8e-16
550537003689	1 probable transmembrane helix predicted for SEN0696 by TMHMM2.0 at aa 17-39
550537003690	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
550537003691	TolA C-terminal; Region: TolA; pfam06519
550537003692	HMMPfam hit to PF06519, Tol-Pal system, TolA, score 2.2e-190
550537003693	1 probable transmembrane helix predicted for SEN0697 by TMHMM2.0 at aa 13-35
550537003694	translocation protein TolB; Provisional; Region: tolB; PRK03629
550537003695	TolB amino-terminal domain; Region: TolB_N; pfam04052
550537003696	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
550537003697	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
550537003698	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
550537003699	HMMPfam hit to PF04052, TolB, N-terminal, score 1.2e-86
550537003700	HMMPfam hit to PF07676, WD40-like Beta Propeller, score 0.48
550537003701	HMMPfam hit to PF07676, WD40-like Beta Propeller, score 3.3e-06
550537003702	HMMPfam hit to PF07676, WD40-like Beta Propeller, score 3.4e-07
550537003703	HMMPfam hit to PF07676, WD40-like Beta Propeller, score 7
550537003704	HMMPfam hit to PF07676, WD40-like Beta Propeller, score 0.057
550537003705	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
550537003706	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
550537003707	ligand binding site [chemical binding]; other site
550537003708	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003709	HMMPfam hit to PF00691, Outer membrane protein, OmpA/MotB, C-terminal, score 6.8e-50
550537003710	PS01068 OmpA-like domain.
550537003711	tol-pal system protein YbgF; Provisional; Region: PRK10803
550537003712	Tetratricopeptide repeat; Region: TPR_6; pfam13174
550537003713	Tetratricopeptide repeat; Region: TPR_6; pfam13174
550537003714	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 0.003
550537003715	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 0.0039
550537003716	quinolinate synthetase; Provisional; Region: PRK09375
550537003717	HMMPfam hit to PF02445, Quinolinate synthetase A, score 2.4e-186
550537003718	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
550537003719	HMMPfam hit to PF04973, Nicotinamide mononucleotide transporter PnuC, score 9.9e-98
550537003720	6 probable transmembrane helices predicted for SEN0702 by TMHMM2.0 at aa 20-42, 49-68, 72-89, 110-127, 158-177 and 184-206
550537003721	zinc transporter ZitB; Provisional; Region: PRK03557
550537003722	HMMPfam hit to PF01545, Cation efflux protein, score 1.8e-113
550537003723	PS00511 Corticotropin-releasing factor family signature.
550537003724	5 probable transmembrane helices predicted for SEN0703 by TMHMM2.0 at aa 21-43, 53-71, 84-106, 121-143 and 164-183
550537003725	YbgS-like protein; Region: YbgS; pfam13985
550537003726	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
550537003727	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
550537003728	HMMPfam hit to PF00793, DAHP synthetase I/KDSA, score 1.1e-185
550537003729	Low G+C region
550537003730	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
550537003731	HMMPfam hit to PF05683, Fe-S type hydro-lyases tartrate/fumarate beta region, score 1.8e-39
550537003732	fumarate hydratase; Provisional; Region: PRK06246
550537003733	HMMPfam hit to PF05681, Fe-S type hydro-lyases tartrate/fumarate alpha region, score 8e-169
550537003734	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537003735	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537003736	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
550537003737	dimerization interface [polypeptide binding]; other site
550537003738	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.1e-20
550537003739	PS00044 Bacterial regulatory proteins, lysR family signature.
550537003740	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.5e-38
550537003741	cell density-dependent motility repressor; Provisional; Region: PRK10082
550537003742	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537003743	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
550537003744	dimerization interface [polypeptide binding]; other site
550537003745	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.4e-05
550537003746	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.7e-17
550537003747	PS00044 Bacterial regulatory proteins, lysR family signature.
550537003748	Note premature stop codon following codon 347
550537003749	HMMPfam hit to PF03600, Divalent ion symporter, score 3e-07
550537003750	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
550537003751	HMMPfam hit to PF04277, Sodium ion-translocating decarboxylase, score 1.6e-33
550537003752	1 probable transmembrane helix predicted for SEN0711 by TMHMM2.0 at aa 10-32
550537003753	oxaloacetate decarboxylase; Provisional; Region: PRK14040
550537003754	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
550537003755	active site
550537003756	catalytic residues [active]
550537003757	metal binding site [ion binding]; metal-binding site
550537003758	homodimer binding site [polypeptide binding]; other site
550537003759	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
550537003760	carboxyltransferase (CT) interaction site; other site
550537003761	biotinylation site [posttranslational modification]; other site
550537003762	HMMPfam hit to PF00682, Pyruvate carboxyltransferase, score 3.3e-90
550537003763	HMMPfam hit to PF02436, Conserved carboxylase region, score 3.7e-99
550537003764	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
550537003765	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 8.9e-28
550537003766	PS00188 Biotin-requiring enzymes attachment site.
550537003767	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
550537003768	9 probable transmembrane helices predicted for SEN0713 by TMHMM2.0 at aa 13-35, 42-64, 125-147, 160-182, 214-236, 266-288, 308-327, 339-361 and 409-431
550537003769	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit, score 5.1e-288
550537003770	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
550537003771	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
550537003772	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537003773	dimer interface [polypeptide binding]; other site
550537003774	putative PBP binding regions; other site
550537003775	ABC-ATPase subunit  interface; other site
550537003776	9 probable transmembrane helices predicted for SEN0715 by TMHMM2.0 at aa 30-49, 81-103, 115-137, 142-161, 174-196, 216-236, 268-290, 305-324 and 331-353
550537003777	HMMPfam hit to PF01032, Bacterial transport system permease protein, score 7.8e-87
550537003778	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
550537003779	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
550537003780	Walker A/P-loop; other site
550537003781	ATP binding site [chemical binding]; other site
550537003782	Q-loop/lid; other site
550537003783	ABC transporter signature motif; other site
550537003784	Walker B; other site
550537003785	D-loop; other site
550537003786	H-loop/switch region; other site
550537003787	HMMPfam hit to PF00005, ABC transporter related, score 2.1e-48
550537003788	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003789	PS00211 ABC transporters family signature.
550537003790	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
550537003791	catalytic core [active]
550537003792	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
550537003793	HMMPfam hit to PF00300, Phosphoglycerate mutase, score 2.9e-44
550537003794	PS00175 Phosphoglycerate mutase family phosphohistidine signature.
550537003795	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
550537003796	active site
550537003797	catalytic residues [active]
550537003798	HMMPfam hit to PF01263, Aldose 1-epimerase, score 2.1e-121
550537003799	PS00545 Aldose 1-epimerase  active site.
550537003800	galactokinase; Provisional; Region: PRK05101
550537003801	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
550537003802	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
550537003803	HMMPfam hit to PF08544, GHMP kinase, C-terminal, score 1.2e-13
550537003804	HMMPfam hit to PF00288, GHMP kinase, score 3e-19
550537003805	PS00627 GHMP kinases  ATP-binding domain.
550537003806	PS00106 Galactokinase signature.
550537003807	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
550537003808	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
550537003809	dimer interface [polypeptide binding]; other site
550537003810	active site
550537003811	HMMPfam hit to PF02744, Galactose-1-phosphate uridyl transferase, C-terminal, score 4.9e-105
550537003812	HMMPfam hit to PF01087, Galactose-1-phosphate uridyl transferase, N-terminal, score 1.5e-103
550537003813	PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature.
550537003814	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
550537003815	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
550537003816	NAD binding site [chemical binding]; other site
550537003817	homodimer interface [polypeptide binding]; other site
550537003818	active site
550537003819	substrate binding site [chemical binding]; other site
550537003820	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 8.4e-88
550537003821	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
550537003822	1 probable transmembrane helix predicted for SEN0722 by TMHMM2.0 at aa 271-293
550537003823	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
550537003824	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537003825	Walker A/P-loop; other site
550537003826	ATP binding site [chemical binding]; other site
550537003827	Q-loop/lid; other site
550537003828	ABC transporter signature motif; other site
550537003829	Walker B; other site
550537003830	D-loop; other site
550537003831	H-loop/switch region; other site
550537003832	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537003833	Walker A/P-loop; other site
550537003834	ATP binding site [chemical binding]; other site
550537003835	Q-loop/lid; other site
550537003836	ABC transporter signature motif; other site
550537003837	Walker B; other site
550537003838	D-loop; other site
550537003839	H-loop/switch region; other site
550537003840	HMMPfam hit to PF00005, ABC transporter related, score 9.7e-51
550537003841	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003842	HMMPfam hit to PF00005, ABC transporter related, score 4.1e-14
550537003843	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003844	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
550537003845	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
550537003846	molybdenum-pterin binding domain; Region: Mop; TIGR00638
550537003847	TOBE domain; Region: TOBE; pfam03459
550537003848	HMMPfam hit to PF03459, Transport-associated OB, type 1, score 1.9e-10
550537003849	HMMPfam hit to PF03459, Transport-associated OB, type 1, score 1.8e-15
550537003850	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 4.7e-15
550537003851	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
550537003852	1 probable transmembrane helix predicted for SEN0725 by TMHMM2.0 at aa 42-64
550537003853	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
550537003854	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537003855	substrate binding pocket [chemical binding]; other site
550537003856	membrane-bound complex binding site; other site
550537003857	hinge residues; other site
550537003858	PS00430 TonB-dependent receptor proteins signature 1.
550537003859	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 4.3e-11
550537003860	PS00435 Peroxidases proximal heme-ligand signature.
550537003861	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
550537003862	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537003863	dimer interface [polypeptide binding]; other site
550537003864	conserved gate region; other site
550537003865	putative PBP binding loops; other site
550537003866	ABC-ATPase subunit interface; other site
550537003867	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 6e-24
550537003868	5 probable transmembrane helices predicted for SEN0727 by TMHMM2.0 at aa 15-37, 49-71, 86-108, 136-158 and 197-219
550537003869	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537003870	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
550537003871	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537003872	Walker A/P-loop; other site
550537003873	ATP binding site [chemical binding]; other site
550537003874	Q-loop/lid; other site
550537003875	ABC transporter signature motif; other site
550537003876	Walker B; other site
550537003877	D-loop; other site
550537003878	H-loop/switch region; other site
550537003879	molybdenum-pterin binding domain; Region: Mop; TIGR00638
550537003880	HMMPfam hit to PF00005, ABC transporter related, score 2.1e-68
550537003881	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003882	PS00211 ABC transporters family signature.
550537003883	HMMPfam hit to PF03459, Transport-associated OB, type 1, score 9.5e-14
550537003884	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
550537003885	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537003886	active site
550537003887	motif I; other site
550537003888	motif II; other site
550537003889	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537003890	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 2.5e-93
550537003891	PS01229 Hypothetical cof family signature 2.
550537003892	PS01228 Hypothetical cof family signature 1.
550537003893	6-phosphogluconolactonase; Provisional; Region: PRK11028
550537003894	acyl-CoA thioesterase; Provisional; Region: PRK10531
550537003895	putative pectinesterase; Region: PLN02432; cl01911
550537003896	HMMPfam hit to PF01095, Pectinesterase, catalytic, score 9.7e-08
550537003897	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003898	imidazolonepropionase; Validated; Region: PRK09356
550537003899	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
550537003900	active site
550537003901	HMMPfam hit to PF01979, Amidohydrolase 1, score 0.00011
550537003902	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
550537003903	putative active site [active]
550537003904	putative metal binding site [ion binding]; other site
550537003905	HMMPfam hit to PF00491, Ureohydrolase, score 1.2e-09
550537003906	PS00147 Arginase family signature 1.
550537003907	PS00148 Arginase family signature 2.
550537003908	histidine utilization repressor; Provisional; Region: PRK14999
550537003909	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537003910	DNA-binding site [nucleotide binding]; DNA binding site
550537003911	UTRA domain; Region: UTRA; pfam07702
550537003912	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 2.6e-23
550537003913	PS00043 Bacterial regulatory proteins, gntR family signature.
550537003914	HMMPfam hit to PF07702, UbiC transcription regulator-associated, score 9.1e-42
550537003915	urocanate hydratase; Provisional; Region: PRK05414
550537003916	HMMPfam hit to PF01175, Urocanase, score 0
550537003917	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003918	PS01233 Urocanase active site.
550537003919	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
550537003920	active sites [active]
550537003921	tetramer interface [polypeptide binding]; other site
550537003922	HMMPfam hit to PF00221, Phenylalanine/histidine ammonia-lyase, score 5.7e-261
550537003923	PS00488 Phenylalanine and histidine ammonia-lyases signature.
550537003924	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
550537003925	substrate binding site [chemical binding]; other site
550537003926	HMMPfam hit to PF01161, PEBP, score 1.7e-07
550537003927	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
550537003928	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
550537003929	inhibitor-cofactor binding pocket; inhibition site
550537003930	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537003931	catalytic residue [active]
550537003932	HMMPfam hit to PF00202, Aminotransferase class-III, score 2.4e-148
550537003933	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
550537003934	biotin synthase; Provisional; Region: PRK15108
550537003935	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537003936	FeS/SAM binding site; other site
550537003937	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
550537003938	HMMPfam hit to PF04055, Radical SAM, score 5.6e-26
550537003939	HMMPfam hit to PF06968, Biotin and thiamin synthesis associated, score 4.2e-53
550537003940	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537003941	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
550537003942	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
550537003943	substrate-cofactor binding pocket; other site
550537003944	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537003945	catalytic residue [active]
550537003946	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 3.6e-88
550537003947	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
550537003948	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
550537003949	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537003950	S-adenosylmethionine binding site [chemical binding]; other site
550537003951	HMMPfam hit to PF08241, Methyltransferase type 11, score 9.4e-33
550537003952	AAA domain; Region: AAA_26; pfam13500
550537003953	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
550537003954	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase, score 3.4e-21
550537003955	excinuclease ABC subunit B; Provisional; Region: PRK05298
550537003956	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537003957	ATP binding site [chemical binding]; other site
550537003958	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537003959	nucleotide binding region [chemical binding]; other site
550537003960	ATP-binding site [chemical binding]; other site
550537003961	Ultra-violet resistance protein B; Region: UvrB; pfam12344
550537003962	UvrB/uvrC motif; Region: UVR; pfam02151
550537003963	HMMPfam hit to PF04851, Restriction endonuclease, type I, R subunit/Type III, Res subunit, score 6.7e-09
550537003964	PS00017 ATP/GTP-binding site motif A (P-loop).
550537003965	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 7.5e-21
550537003966	HMMPfam hit to PF02151, UvrB/UvrC protein, score 3.1e-14
550537003967	Note the premature stop codon following codon 278 and the frameshift mutation following codon 521
550537003968	HMMPfam hit to PF00560, Leucine-rich repeat, score 2.9
550537003969	HMMPfam hit to PF00560, Leucine-rich repeat, score 3.4
550537003970	HMMPfam hit to PF00560, Leucine-rich repeat, score 2.5
550537003971	HMMPfam hit to PF00560, Leucine-rich repeat, score 8.6
550537003972	HMMPfam hit to PF00560, Leucine-rich repeat, score 2.4
550537003973	HMMPfam hit to PF00560, Leucine-rich repeat, score 3
550537003974	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
550537003975	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
550537003976	putative substrate binding pocket [chemical binding]; other site
550537003977	dimer interface [polypeptide binding]; other site
550537003978	phosphate binding site [ion binding]; other site
550537003979	HMMPfam hit to PF01933, Protein of unknown function UPF0052 and CofD, score 1.1e-129
550537003980	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
550537003981	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537003982	FeS/SAM binding site; other site
550537003983	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
550537003984	HMMPfam hit to PF04055, Radical SAM, score 2.8e-38
550537003985	PS01305 moaA / nifB / pqqE family signature.
550537003986	HMMPfam hit to PF06463, Molybdenum cofactor synthesis C-terminal, score 4.5e-49
550537003987	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
550537003988	MPT binding site; other site
550537003989	trimer interface [polypeptide binding]; other site
550537003990	HMMPfam hit to PF00994, Molybdopterin binding, score 3.7e-43
550537003991	PS01078 Molybdenum cofactor biosynthesis proteins signature 1.
550537003992	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
550537003993	trimer interface [polypeptide binding]; other site
550537003994	dimer interface [polypeptide binding]; other site
550537003995	putative active site [active]
550537003996	HMMPfam hit to PF01967, Molybdopterin cofactor biosynthesis MoaC region, score 2.6e-96
550537003997	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
550537003998	MoaE interaction surface [polypeptide binding]; other site
550537003999	MoeB interaction surface [polypeptide binding]; other site
550537004000	thiocarboxylated glycine; other site
550537004001	HMMPfam hit to PF02597, ThiamineS, score 1.1e-27
550537004002	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
550537004003	MoaE homodimer interface [polypeptide binding]; other site
550537004004	MoaD interaction [polypeptide binding]; other site
550537004005	active site residues [active]
550537004006	HMMPfam hit to PF02391, Molybdopterin biosynthesis MoaE, score 5.6e-61
550537004007	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
550537004008	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
550537004009	HMMPfam hit to PF01027, Protein of unknown function UPF0005, score 1.2e-55
550537004010	7 probable transmembrane helices predicted for SEN0753 by TMHMM2.0 at aa 20-42, 57-76, 88-107, 112-131, 138-160, 165-184 and 209-231
550537004011	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
550537004012	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
550537004013	7 probable transmembrane helices predicted for SEN0754 by TMHMM2.0 at aa 21-43, 48-70, 77-99, 103-125, 132-154, 159-181 and 202-224
550537004014	4 probable transmembrane helices predicted for SEN0755 by TMHMM2.0 at aa 64-83, 93-115, 120-142 and 157-179
550537004015	4 probable transmembrane helices predicted for SEN0756 by TMHMM2.0 at aa 44-66, 81-103, 115-137 and 147-169
550537004016	Predicted integral membrane protein [Function unknown]; Region: COG0392
550537004017	8 probable transmembrane helices predicted for SEN0757 by TMHMM2.0 at aa 13-30, 50-72, 85-107, 127-149, 162-184, 204-226, 233-255 and 281-303
550537004018	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004019	cardiolipin synthase 2; Provisional; Region: PRK11263
550537004020	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
550537004021	putative active site [active]
550537004022	catalytic site [active]
550537004023	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
550537004024	putative active site [active]
550537004025	catalytic site [active]
550537004026	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 1.3
550537004027	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 2.6e-07
550537004028	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
550537004029	putative catalytic site [active]
550537004030	putative metal binding site [ion binding]; other site
550537004031	putative phosphate binding site [ion binding]; other site
550537004032	HMMPfam hit to PF03372, Endonuclease/exonuclease/phosphatase, score 9.7e-28
550537004033	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
550537004034	4 probable transmembrane helices predicted for SEN0760 by TMHMM2.0 at aa 13-32, 36-58, 79-96 and 100-119
550537004035	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
550537004036	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
550537004037	6 probable transmembrane helices predicted for SEN0761 by TMHMM2.0 at aa 24-46, 173-195, 223-245, 255-277, 284-303 and 338-360
550537004038	HMMPfam hit to PF01061, ABC-2 type transporter, score 3.3e-42
550537004039	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
550537004040	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
550537004041	6 probable transmembrane helices predicted for SEN0762 by TMHMM2.0 at aa 26-48, 181-203, 230-252, 262-284, 291-313 and 347-369
550537004042	HMMPfam hit to PF01061, ABC-2 type transporter, score 6.3e-24
550537004043	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
550537004044	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
550537004045	Walker A/P-loop; other site
550537004046	ATP binding site [chemical binding]; other site
550537004047	Q-loop/lid; other site
550537004048	ABC transporter signature motif; other site
550537004049	Walker B; other site
550537004050	D-loop; other site
550537004051	H-loop/switch region; other site
550537004052	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
550537004053	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
550537004054	Walker A/P-loop; other site
550537004055	ATP binding site [chemical binding]; other site
550537004056	Q-loop/lid; other site
550537004057	ABC transporter signature motif; other site
550537004058	Walker B; other site
550537004059	D-loop; other site
550537004060	H-loop/switch region; other site
550537004061	HMMPfam hit to PF00005, ABC transporter related, score 3.2e-47
550537004062	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004063	HMMPfam hit to PF00005, ABC transporter related, score 1.9e-38
550537004064	PS00211 ABC transporters family signature.
550537004065	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004066	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
550537004067	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
550537004068	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537004069	HMMPfam hit to PF00529, Secretion protein HlyD, score 5.3e-19
550537004070	1 probable transmembrane helix predicted for SEN0764 by TMHMM2.0 at aa 5-27
550537004071	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
550537004072	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537004073	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
550537004074	HMMPfam hit to PF09209, Transcriptional regulator, YbiH, C-terminal, score 1e-40
550537004075	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 5.1e-16
550537004076	PS01081 Bacterial regulatory proteins, tetR family signature.
550537004077	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
550537004078	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
550537004079	ATP binding site [chemical binding]; other site
550537004080	Mg++ binding site [ion binding]; other site
550537004081	motif III; other site
550537004082	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537004083	nucleotide binding region [chemical binding]; other site
550537004084	ATP-binding site [chemical binding]; other site
550537004085	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 3.5e-74
550537004086	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004087	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
550537004088	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 4.9e-34
550537004089	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
550537004090	DEAD_2; Region: DEAD_2; pfam06733
550537004091	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
550537004092	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004093	glycosyl transferase family protein; Provisional; Region: PRK08136
550537004094	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
550537004095	HMMPfam hit to PF02885, Glycosyl transferase, family 3, score 9.8e-26
550537004096	hypothetical protein; Provisional; Region: PRK10259
550537004097	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 5.8e-34
550537004098	hypothetical protein; Provisional; Region: PRK11019
550537004099	HMMPfam hit to PF01258, Zinc finger, DksA/TraR C4-type, score 3.5e-33
550537004100	PS01102 Prokaryotic dksA/traR C4-type zinc finger.
550537004101	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
550537004102	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
550537004103	HMMPfam hit to PF05971, Protein of unknown function DUF890, score 6.8e-209
550537004104	putative mechanosensitive channel protein; Provisional; Region: PRK11465
550537004105	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537004106	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 2.4e-63
550537004107	11 probable transmembrane helices predicted for SEN0772 by TMHMM2.0 at aa 5-27, 136-158, 179-201, 216-238, 267-284, 294-313, 333-355, 370-392, 427-449, 464-486 and 507-529
550537004108	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
550537004109	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
550537004110	Walker A/P-loop; other site
550537004111	ATP binding site [chemical binding]; other site
550537004112	Q-loop/lid; other site
550537004113	ABC transporter signature motif; other site
550537004114	Walker B; other site
550537004115	D-loop; other site
550537004116	H-loop/switch region; other site
550537004117	HMMPfam hit to PF00005, ABC transporter related, score 1e-70
550537004118	PS00211 ABC transporters family signature.
550537004119	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004120	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537004121	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537004122	dimer interface [polypeptide binding]; other site
550537004123	conserved gate region; other site
550537004124	putative PBP binding loops; other site
550537004125	ABC-ATPase subunit interface; other site
550537004126	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 4.6e-39
550537004127	5 probable transmembrane helices predicted for SEN0774 by TMHMM2.0 at aa 20-42, 55-77, 92-114, 155-177 and 187-209
550537004128	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537004129	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
550537004130	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537004131	substrate binding pocket [chemical binding]; other site
550537004132	membrane-bound complex binding site; other site
550537004133	hinge residues; other site
550537004134	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 3.5e-93
550537004135	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537004136	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
550537004137	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
550537004138	dimerization interface [polypeptide binding]; other site
550537004139	DPS ferroxidase diiron center [ion binding]; other site
550537004140	ion pore; other site
550537004141	HMMPfam hit to PF00210, Ferritin and Dps, score 9.4e-13
550537004142	PS00819 Dps protein family signature 2.
550537004143	PS00818 Dps protein family signature 1.
550537004144	threonine and homoserine efflux system; Provisional; Region: PRK10532
550537004145	EamA-like transporter family; Region: EamA; pfam00892
550537004146	10 probable transmembrane helices predicted for SEN0777 by TMHMM2.0 at aa 7-24, 37-59, 72-89, 93-115, 122-139, 143-165, 177-199, 203-225, 238-257 and 261-283
550537004147	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 6.7e-19
550537004148	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004149	outer membrane protein X; Provisional; Region: ompX; PRK09408
550537004150	HMMPfam hit to PF06316, Virulence-related outer membrane protein, score 1.7e-17
550537004151	1 probable transmembrane helix predicted for SEN0778 by TMHMM2.0 at aa 7-29
550537004152	PS00694 Enterobacterial virulence outer membrane protein signature 1.
550537004153	PS00695 Enterobacterial virulence outer membrane protein signature 2.
550537004154	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
550537004155	Sulfatase; Region: Sulfatase; pfam00884
550537004156	HMMPfam hit to PF00884, Sulphatase, score 3.6e-68
550537004157	4 probable transmembrane helices predicted for SEN0779 by TMHMM2.0 at aa 32-54, 63-85, 105-127 and 144-166
550537004158	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004159	manganese transport regulator MntR; Provisional; Region: PRK11050
550537004160	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
550537004161	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
550537004162	HMMPfam hit to PF01325, Iron dependent repressor, score 1.9e-05
550537004163	HMMPfam hit to PF02742, Iron dependent repressor, score 6.6e-07
550537004164	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
550537004165	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
550537004166	transmembrane helices; other site
550537004167	HMMPfam hit to PF03600, Divalent ion symporter, score 4.3e-07
550537004168	8 probable transmembrane helices predicted for SEN0781 by TMHMM2.0 at aa 22-44, 64-86, 142-164, 203-222, 226-248, 261-283, 293-315 and 327-349
550537004169	L,D-transpeptidase; Provisional; Region: PRK10260
550537004170	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
550537004171	HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 9.2e-68
550537004172	1 probable transmembrane helix predicted for SEN0782 by TMHMM2.0 at aa 7-29
550537004173	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
550537004174	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537004175	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537004176	Walker A/P-loop; other site
550537004177	ATP binding site [chemical binding]; other site
550537004178	ABC transporter signature motif; other site
550537004179	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537004180	Walker B; other site
550537004181	ABC transporter; Region: ABC_tran_2; pfam12848
550537004182	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537004183	HMMPfam hit to PF00005, ABC transporter related, score 3.2e-40
550537004184	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004185	HMMPfam hit to PF00005, ABC transporter related, score 9.7e-46
550537004186	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004187	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
550537004188	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
550537004189	HMMPfam hit to PF07350, Protein of unknown function DUF1479, score 0
550537004190	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
550537004191	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537004192	active site
550537004193	motif I; other site
550537004194	motif II; other site
550537004195	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537004196	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 8.2e-65
550537004197	PS01229 Hypothetical cof family signature 2.
550537004198	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
550537004199	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
550537004200	dimer interface [polypeptide binding]; other site
550537004201	active site
550537004202	glycine loop; other site
550537004203	HMMPfam hit to PF01228, Formate C-acetyltransferase glycine radical, score 4e-22
550537004204	PS00850 Glycine radical signature.
550537004205	HMMPfam hit to PF02901, Pyruvate formate-lyase, PFL, score 0
550537004206	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
550537004207	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537004208	FeS/SAM binding site; other site
550537004209	HMMPfam hit to PF04055, Radical SAM, score 2.6e-12
550537004210	PS01087 Radical activating enzymes signature.
550537004211	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
550537004212	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
550537004213	ATP binding site [chemical binding]; other site
550537004214	substrate interface [chemical binding]; other site
550537004215	HMMPfam hit to PF05237, MoeZ/MoeB, score 5.8e-35
550537004216	HMMPfam hit to PF00899, UBA/THIF-type NAD/FAD binding fold, score 1.1e-63
550537004217	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004218	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
550537004219	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
550537004220	dimer interface [polypeptide binding]; other site
550537004221	putative functional site; other site
550537004222	putative MPT binding site; other site
550537004223	HMMPfam hit to PF03454, MoeA, C-terminal, domain IV, score 9.2e-26
550537004224	HMMPfam hit to PF00994, Molybdopterin binding, score 7e-52
550537004225	PS01079 Molybdenum cofactor biosynthesis proteins signature 2.
550537004226	HMMPfam hit to PF03453, MoeA, N-terminal, domain I and II, score 5.2e-83
550537004227	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
550537004228	catalytic nucleophile [active]
550537004229	HMMPfam hit to PF01112, Peptidase T2, asparaginase 2, score 2.4e-170
550537004230	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004231	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
550537004232	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537004233	Walker A/P-loop; other site
550537004234	ATP binding site [chemical binding]; other site
550537004235	Q-loop/lid; other site
550537004236	ABC transporter signature motif; other site
550537004237	Walker B; other site
550537004238	D-loop; other site
550537004239	H-loop/switch region; other site
550537004240	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
550537004241	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537004242	Walker A/P-loop; other site
550537004243	ATP binding site [chemical binding]; other site
550537004244	Q-loop/lid; other site
550537004245	ABC transporter signature motif; other site
550537004246	Walker B; other site
550537004247	D-loop; other site
550537004248	H-loop/switch region; other site
550537004249	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
550537004250	HMMPfam hit to PF00005, ABC transporter related, score 1.6e-58
550537004251	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004252	PS00211 ABC transporters family signature.
550537004253	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 7.5e-07
550537004254	HMMPfam hit to PF00005, ABC transporter related, score 5.4e-59
550537004255	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004256	PS00211 ABC transporters family signature.
550537004257	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 2.5e-09
550537004258	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
550537004259	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
550537004260	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 1.5e-93
550537004261	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
550537004262	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537004263	dimer interface [polypeptide binding]; other site
550537004264	conserved gate region; other site
550537004265	putative PBP binding loops; other site
550537004266	ABC-ATPase subunit interface; other site
550537004267	6 probable transmembrane helices predicted for SEN0796 by TMHMM2.0 at aa 9-31, 101-123, 135-157, 172-189, 227-249 and 278-300
550537004268	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1e-55
550537004269	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537004270	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
550537004271	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
550537004272	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537004273	dimer interface [polypeptide binding]; other site
550537004274	conserved gate region; other site
550537004275	putative PBP binding loops; other site
550537004276	ABC-ATPase subunit interface; other site
550537004277	6 probable transmembrane helices predicted for SEN0797 by TMHMM2.0 at aa 39-61, 107-129, 136-158, 163-185, 209-231 and 266-288
550537004278	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 7.3e-47
550537004279	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537004280	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
550537004281	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
550537004282	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537004283	FeS/SAM binding site; other site
550537004284	HMMPfam hit to PF01938, Deoxyribonuclease/rho motif-related TRAM, score 0.019
550537004285	HMMPfam hit to PF04055, Radical SAM, score 6.2e-29
550537004286	PS01278 Uncharacterized protein family UPF0004 signature.
550537004287	HMMPfam hit to PF00919, Protein of unknown function UPF0004, N-terminal, score 8.2e-42
550537004288	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
550537004289	Salmonella Pathogenicity Island 14: SPI-14
550537004290	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
550537004291	HMMPfam hit to PF03328, HpcH/HpaI aldolase, score 1.1e-05
550537004292	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
550537004293	Ligand binding site [chemical binding]; other site
550537004294	Electron transfer flavoprotein domain; Region: ETF; pfam01012
550537004295	HMMPfam hit to PF01012, Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, score 1.9e-57
550537004296	PS01065 Electron transfer flavoprotein beta-subunit signature.
550537004297	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
550537004298	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
550537004299	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
550537004300	HMMPfam hit to PF01012, Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, score 1.3e-27
550537004301	HMMPfam hit to PF00766, Electron transfer flavoprotein, alpha subunit, C-terminal, score 1.9e-55
550537004302	PS00696 Electron transfer flavoprotein alpha-subunit signature.
550537004303	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
550537004304	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
550537004305	active site
550537004306	HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal, score 5e-13
550537004307	HMMPfam hit to PF02770, Acyl-CoA dehydrogenase/oxidase, central region, score 2.5e-22
550537004308	HMMPfam hit to PF00441, Acyl-CoA oxidase/dehydrogenase, type 1, score 1e-35
550537004309	PS00073 Acyl-CoA dehydrogenases signature 2.
550537004310	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
550537004311	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537004312	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
550537004313	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
550537004314	HMMPfam hit to PF01494, Monooxygenase, FAD-binding, score 2.7e-08
550537004315	HMMPfam hit to PF05187, Electron transfer flavoprotein-ubiquinone oxidoreductase, score 2.8e-73
550537004316	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537004317	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537004318	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
550537004319	putative dimerization interface [polypeptide binding]; other site
550537004320	HMMPfam hit to PF03466, LysR, substrate-binding, score 5.7e-36
550537004321	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2e-14
550537004322	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
550537004323	3 probable transmembrane helices predicted for SEN0806 by TMHMM2.0 at aa 7-29, 53-75 and 96-118
550537004324	HMMPfam hit to PF03600, Divalent ion symporter, score 1.8e-23
550537004325	Note the PFam motif: PF03811 Insertion element protein; Appears to be the remnant following a large deletion event
550537004326	HMMPfam hit to PF03811, Insertion element protein, score 1.1e-28
550537004327	HMMPfam hit to PF07995, Glucose sorbosone dehydrogenase, score 1.2e-44
550537004328	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
550537004329	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
550537004330	putative C-terminal domain interface [polypeptide binding]; other site
550537004331	putative GSH binding site (G-site) [chemical binding]; other site
550537004332	putative dimer interface [polypeptide binding]; other site
550537004333	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
550537004334	putative N-terminal domain interface [polypeptide binding]; other site
550537004335	putative dimer interface [polypeptide binding]; other site
550537004336	putative substrate binding pocket (H-site) [chemical binding]; other site
550537004337	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 3.8e-10
550537004338	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 7.3e-11
550537004339	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
550537004340	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
550537004341	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
550537004342	HMMPfam hit to PF00768, Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, score 1.5e-149
550537004343	HMMPfam hit to PF07943, Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal, score 1.1e-38
550537004344	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
550537004345	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
550537004346	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537004347	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 4.7e-70
550537004348	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 1.2e-16
550537004349	PS00894 Bacterial regulatory proteins, deoR family signature.
550537004350	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
550537004351	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
550537004352	active site
550537004353	4 probable transmembrane helices predicted for SEN0811 by TMHMM2.0 at aa 26-48, 60-82, 126-148 and 155-177
550537004354	HMMPfam hit to PF01569, Phosphatidic acid phosphatase type 2-like, score 1.3e-29
550537004355	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004356	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
550537004357	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537004358	putative substrate translocation pore; other site
550537004359	12 probable transmembrane helices predicted for SEN0812 by TMHMM2.0 at aa 16-38, 53-72, 84-101, 111-130, 142-164, 169-188, 220-242, 257-279, 286-308, 313-335, 348-367 and 377-399
550537004360	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.4e-28
550537004361	PS00216 Sugar transport proteins signature 1.
550537004362	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
550537004363	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537004364	active site
550537004365	motif I; other site
550537004366	motif II; other site
550537004367	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537004368	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 4.3e-66
550537004369	PS01229 Hypothetical cof family signature 2.
550537004370	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537004371	putative substrate translocation pore; other site
550537004372	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537004373	12 probable transmembrane helices predicted for SEN0814 by TMHMM2.0 at aa 13-35, 50-72, 79-101, 105-124, 145-167, 171-190, 211-233, 253-275, 282-301, 305-327, 340-362 and 367-389
550537004374	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.2e-24
550537004375	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
550537004376	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537004377	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
550537004378	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 7.6e-09
550537004379	putative transporter; Provisional; Region: PRK04972
550537004380	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
550537004381	TrkA-C domain; Region: TrkA_C; pfam02080
550537004382	TrkA-C domain; Region: TrkA_C; pfam02080
550537004383	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
550537004384	9 probable transmembrane helices predicted for SEN0816 by TMHMM2.0 at aa 13-35, 64-86, 93-115, 159-181, 383-402, 406-428, 449-471, 476-498 and 535-557
550537004385	HMMPfam hit to PF06826, YidE/YbjL duplication, score 2.4e-62
550537004386	HMMPfam hit to PF02080, TrkA-C, score 6.3e-12
550537004387	HMMPfam hit to PF02080, TrkA-C, score 2.6e-11
550537004388	HMMPfam hit to PF06826, YidE/YbjL duplication, score 3e-67
550537004389	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
550537004390	4 probable transmembrane helices predicted for SEN0817 by TMHMM2.0 at aa 7-29, 34-56, 61-83 and 93-115
550537004391	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
550537004392	GSH binding site [chemical binding]; other site
550537004393	catalytic residues [active]
550537004394	HMMPfam hit to PF00462, Glutaredoxin, score 2.1e-15
550537004395	PS00195 Glutaredoxin active site.
550537004396	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
550537004397	HMMPfam hit to PF07214, Protein of unknown function DUF1418, score 3.6e-72
550537004398	2 probable transmembrane helices predicted for SEN0819 by TMHMM2.0 at aa 13-35 and 45-67
550537004400	HMMPfam hit to PF00881, Nitroreductase, score 7.8e-36
550537004401	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
550537004402	RimK-like ATP-grasp domain; Region: RimK; pfam08443
550537004403	HMMPfam hit to PF08443, ATP-grasp fold, RimK-type, score 2.2e-112
550537004404	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
550537004405	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
550537004406	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
550537004407	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 3.8e-11
550537004408	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
550537004409	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537004410	Walker A/P-loop; other site
550537004411	ATP binding site [chemical binding]; other site
550537004412	Q-loop/lid; other site
550537004413	ABC transporter signature motif; other site
550537004414	Walker B; other site
550537004415	D-loop; other site
550537004416	H-loop/switch region; other site
550537004417	TOBE domain; Region: TOBE_2; pfam08402
550537004418	HMMPfam hit to PF00005, ABC transporter related, score 4e-65
550537004419	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004420	PS00211 ABC transporters family signature.
550537004421	HMMPfam hit to PF08402, Transport-associated OB, type 2, score 6.8e-25
550537004422	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537004423	dimer interface [polypeptide binding]; other site
550537004424	conserved gate region; other site
550537004425	putative PBP binding loops; other site
550537004426	ABC-ATPase subunit interface; other site
550537004427	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
550537004428	6 probable transmembrane helices predicted for SEN0825 by TMHMM2.0 at aa 31-52, 100-122, 135-157, 185-207, 228-250 and 284-306
550537004429	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 2.5e-33
550537004430	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537004431	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
550537004432	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537004433	dimer interface [polypeptide binding]; other site
550537004434	conserved gate region; other site
550537004435	putative PBP binding loops; other site
550537004436	ABC-ATPase subunit interface; other site
550537004437	6 probable transmembrane helices predicted for SEN0826 by TMHMM2.0 at aa 13-35, 69-91, 104-126, 141-163, 184-206 and 242-264
550537004438	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 0.00041
550537004439	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004440	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537004441	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
550537004442	4 probable transmembrane helices predicted for SEN0827 by TMHMM2.0 at aa 13-35, 60-82, 89-111 and 126-148
550537004443	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
550537004444	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537004445	S-adenosylmethionine binding site [chemical binding]; other site
550537004446	HMMPfam hit to PF05958, (Uracil-5)-methyltransferase, score 3.9e-06
550537004447	PS01230 RNA methyltransferase trmA family signature 1.
550537004448	PS01231 RNA methyltransferase trmA family signature 2.
550537004449	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
550537004450	HMMPfam hit to PF04215,  sugar-specific permease, SgaT/UlaA, score 1.6e-92
550537004451	11 probable transmembrane helices predicted for SEN0829 by TMHMM2.0 at aa 15-37, 44-66, 103-125, 132-154, 159-181, 233-255, 270-292, 330-352, 356-378, 385-407 and 422-444
550537004452	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
550537004453	active site
550537004454	P-loop; other site
550537004455	phosphorylation site [posttranslational modification]
550537004456	HMMPfam hit to PF02302, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, score 4.6e-08
550537004457	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
550537004458	Sulfatase; Region: Sulfatase; cl17466
550537004459	HMMPfam hit to PF00884, Sulphatase, score 1.4e-16
550537004460	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
550537004461	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537004462	substrate binding pocket [chemical binding]; other site
550537004463	membrane-bound complex binding site; other site
550537004464	hinge residues; other site
550537004465	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 4.3e-104
550537004466	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537004467	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537004468	dimer interface [polypeptide binding]; other site
550537004469	conserved gate region; other site
550537004470	putative PBP binding loops; other site
550537004471	ABC-ATPase subunit interface; other site
550537004472	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 2.9e-09
550537004473	5 probable transmembrane helices predicted for SEN0833 by TMHMM2.0 at aa 15-37, 46-68, 83-105, 155-174 and 189-211
550537004474	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537004475	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537004476	dimer interface [polypeptide binding]; other site
550537004477	conserved gate region; other site
550537004478	putative PBP binding loops; other site
550537004479	ABC-ATPase subunit interface; other site
550537004480	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 9e-19
550537004481	4 probable transmembrane helices predicted for SEN0834 by TMHMM2.0 at aa 10-32, 45-67, 101-118 and 201-223
550537004482	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537004483	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
550537004484	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537004485	substrate binding pocket [chemical binding]; other site
550537004486	membrane-bound complex binding site; other site
550537004487	hinge residues; other site
550537004488	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 6.1e-94
550537004489	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537004490	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
550537004491	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537004492	Walker A/P-loop; other site
550537004493	ATP binding site [chemical binding]; other site
550537004494	Q-loop/lid; other site
550537004495	ABC transporter signature motif; other site
550537004496	Walker B; other site
550537004497	D-loop; other site
550537004498	H-loop/switch region; other site
550537004499	HMMPfam hit to PF00005, ABC transporter related, score 3.4e-76
550537004500	PS00211 ABC transporters family signature.
550537004501	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004502	putative lipoprotein; Provisional; Region: PRK10533
550537004503	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004504	hypothetical protein; Provisional; Region: PRK02877
550537004505	HMMPfam hit to PF01906, Protein of unknown function DUF74, score 1.6e-65
550537004506	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
550537004507	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
550537004508	amidase catalytic site [active]
550537004509	Zn binding residues [ion binding]; other site
550537004510	substrate binding site [chemical binding]; other site
550537004511	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004512	HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, family 2, score 1.1e-41
550537004513	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
550537004514	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
550537004515	NAD(P) binding site [chemical binding]; other site
550537004516	active site
550537004517	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 7.2e-19
550537004518	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
550537004519	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
550537004520	putative NAD(P) binding site [chemical binding]; other site
550537004521	putative active site [active]
550537004522	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
550537004523	1 probable transmembrane helix predicted for SEN0841 by TMHMM2.0 at aa 438-460
550537004524	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 4.3e-11
550537004525	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
550537004526	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
550537004527	tetramer interface [polypeptide binding]; other site
550537004528	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537004529	catalytic residue [active]
550537004530	HMMPfam hit to PF01212, Aromatic amino acid beta-eliminating lyase/threonine aldolase, score 1.2e-153
550537004531	pyruvate dehydrogenase; Provisional; Region: PRK09124
550537004532	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
550537004533	PYR/PP interface [polypeptide binding]; other site
550537004534	dimer interface [polypeptide binding]; other site
550537004535	tetramer interface [polypeptide binding]; other site
550537004536	TPP binding site [chemical binding]; other site
550537004537	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
550537004538	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
550537004539	TPP-binding site [chemical binding]; other site
550537004540	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding, score 7.2e-61
550537004541	PS00187 Thiamine pyrophosphate enzymes signature.
550537004542	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central region, score 2.4e-47
550537004543	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding region, score 3.8e-81
550537004544	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
550537004545	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
550537004546	FAD binding pocket [chemical binding]; other site
550537004547	FAD binding motif [chemical binding]; other site
550537004548	phosphate binding motif [ion binding]; other site
550537004549	beta-alpha-beta structure motif; other site
550537004550	NAD binding pocket [chemical binding]; other site
550537004551	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
550537004552	catalytic loop [active]
550537004553	iron binding site [ion binding]; other site
550537004554	HMMPfam hit to PF00111, Ferredoxin, score 3.1e-20
550537004555	HMMPfam hit to PF00175, Oxidoreductase FAD/NAD(P)-binding, score 2.5e-08
550537004556	HMMPfam hit to PF00970, Oxidoreductase FAD-binding region, score 7.5e-09
550537004557	hybrid cluster protein; Provisional; Region: PRK05290
550537004558	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
550537004559	ACS interaction site; other site
550537004560	CODH interaction site; other site
550537004561	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
550537004562	hybrid metal cluster; other site
550537004563	HMMPfam hit to PF03063, Prismane, score 5.6e-259
550537004564	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004565	Predicted membrane protein [Function unknown]; Region: COG2431
550537004566	HMMPfam hit to PF03956, Protein of unknown function DUF340, prokaryotic membrane, score 1.4e-87
550537004567	6 probable transmembrane helices predicted for SEN0846 by TMHMM2.0 at aa 25-47, 75-97, 102-119, 131-153, 168-190 and 239-261
550537004568	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
550537004569	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
550537004570	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
550537004571	putative active site [active]
550537004572	putative metal-binding site [ion binding]; other site
550537004573	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004574	Protein of unknown function (DUF535); Region: DUF535; pfam04393
550537004575	HMMPfam hit to PF04393, Protein of unknown function DUF535, score 1.6e-93
550537004576	macrolide transporter subunit MacA; Provisional; Region: PRK11578
550537004577	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537004578	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537004579	1 probable transmembrane helix predicted for SEN0849 by TMHMM2.0 at aa 13-30
550537004580	HMMPfam hit to PF00529, Secretion protein HlyD, score 8.1e-09
550537004581	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
550537004582	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
550537004583	Walker A/P-loop; other site
550537004584	ATP binding site [chemical binding]; other site
550537004585	Q-loop/lid; other site
550537004586	ABC transporter signature motif; other site
550537004587	Walker B; other site
550537004588	D-loop; other site
550537004589	H-loop/switch region; other site
550537004590	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
550537004591	FtsX-like permease family; Region: FtsX; pfam02687
550537004592	HMMPfam hit to PF00005, ABC transporter related, score 2.1e-60
550537004593	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004594	PS00211 ABC transporters family signature.
550537004595	5 probable transmembrane helices predicted for SEN0850 by TMHMM2.0 at aa 270-292, 418-437, 524-546, 572-594 and 609-631
550537004596	HMMPfam hit to PF02687, Protein of unknown function DUF214, permase predicted, score 6.5e-53
550537004597	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
550537004598	DNA-binding site [nucleotide binding]; DNA binding site
550537004599	RNA-binding motif; other site
550537004600	HMMPfam hit to PF00313, Cold-shock protein, DNA-binding, score 1.7e-39
550537004601	PS00352 'Cold-shock' DNA-binding domain signature.
550537004602	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
550537004603	HMMPfam hit to PF02617, Adaptor protein ClpS, core, score 1.7e-49
550537004604	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
550537004605	Clp amino terminal domain; Region: Clp_N; pfam02861
550537004606	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537004607	Walker A motif; other site
550537004608	ATP binding site [chemical binding]; other site
550537004609	Walker B motif; other site
550537004610	arginine finger; other site
550537004611	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537004612	Walker A motif; other site
550537004613	ATP binding site [chemical binding]; other site
550537004614	Walker B motif; other site
550537004615	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
550537004616	HMMPfam hit to PF02861, Clp, N-terminal, score 7.5e-17
550537004617	HMMPfam hit to PF00004, AAA ATPase, core, score 2.1e-22
550537004618	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004619	PS00870 Chaperonins clpA/B signature 1.
550537004620	HMMPfam hit to PF07724, ATPase AAA-2, score 1.7e-88
550537004621	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004622	PS00871 Chaperonins clpA/B signature 2.
550537004623	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
550537004624	DNA binding site [nucleotide binding]
550537004625	active site
550537004626	Int/Topo IB signature motif; other site
550537004627	1 probable transmembrane helix predicted for SEN0853B by TMHMM2.0 at aa 157-179
550537004628	Isochorismatase family; Region: Isochorismatase; pfam00857
550537004629	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
550537004630	catalytic triad [active]
550537004631	dimer interface [polypeptide binding]; other site
550537004632	conserved cis-peptide bond; other site
550537004633	HMMPfam hit to PF00857, Isochorismatase hydrolase, score 7.8e-21
550537004634	Pirin-related protein [General function prediction only]; Region: COG1741
550537004635	Pirin; Region: Pirin; pfam02678
550537004636	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
550537004637	HMMPfam hit to PF05726, Pirin, C-terminal, score 9.3e-48
550537004638	HMMPfam hit to PF02678, Pirin, N-terminal, score 1.2e-55
550537004639	LysR family transcriptional regulator; Provisional; Region: PRK14997
550537004640	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537004641	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
550537004642	putative effector binding pocket; other site
550537004643	putative dimerization interface [polypeptide binding]; other site
550537004644	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 5.7e-14
550537004645	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.2e-41
550537004646	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
550537004647	rRNA binding site [nucleotide binding]; other site
550537004648	predicted 30S ribosome binding site; other site
550537004649	HMMPfam hit to PF01176, S1, IF1 type, score 2.1e-37
550537004650	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
550537004651	HMMPfam hit to PF03588, Leucyl/phenylalanyl-tRNA-protein transferase, score 1.3e-108
550537004652	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
550537004653	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537004654	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537004655	Walker A/P-loop; other site
550537004656	ATP binding site [chemical binding]; other site
550537004657	Q-loop/lid; other site
550537004658	ABC transporter signature motif; other site
550537004659	Walker B; other site
550537004660	D-loop; other site
550537004661	H-loop/switch region; other site
550537004662	HMMPfam hit to PF00005, ABC transporter related, score 5.2e-61
550537004663	PS00211 ABC transporters family signature.
550537004664	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004665	6 probable transmembrane helices predicted for SEN0860 by TMHMM2.0 at aa 20-42, 47-69, 133-155, 160-182, 246-268 and 278-300
550537004666	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
550537004667	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537004668	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537004669	Walker A/P-loop; other site
550537004670	ATP binding site [chemical binding]; other site
550537004671	Q-loop/lid; other site
550537004672	ABC transporter signature motif; other site
550537004673	Walker B; other site
550537004674	D-loop; other site
550537004675	H-loop/switch region; other site
550537004676	HMMPfam hit to PF00005, ABC transporter related, score 1.6e-68
550537004677	PS00211 ABC transporters family signature.
550537004678	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004679	6 probable transmembrane helices predicted for SEN0861 by TMHMM2.0 at aa 24-46, 61-80, 137-159, 163-185, 245-267 and 282-304
550537004680	HMMPfam hit to PF00664, ABC transporter, transmembrane region, score 1.8e-48
550537004681	thioredoxin reductase; Provisional; Region: PRK10262
550537004682	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537004683	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537004684	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 4.2e-54
550537004685	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 1.1e-25
550537004686	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
550537004687	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
550537004688	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537004689	putative DNA binding site [nucleotide binding]; other site
550537004690	putative Zn2+ binding site [ion binding]; other site
550537004691	AsnC family; Region: AsnC_trans_reg; pfam01037
550537004692	PS00519 Bacterial regulatory proteins, asnC family signature.
550537004693	HMMPfam hit to PF01037, Bacterial regulatory proteins, AsnC/Lrp, score 5.2e-31
550537004694	DNA translocase FtsK; Provisional; Region: PRK10263
550537004695	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
550537004696	DNA translocase FtsK; Provisional; Region: PRK10263
550537004697	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
550537004698	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
550537004699	5 probable transmembrane helices predicted for SEN0864 by TMHMM2.0 at aa 22-44, 75-97, 110-132, 137-158 and 165-187
550537004700	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004701	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004702	HMMPfam hit to PF01580, Cell divisionFtsK/SpoIIIE, score 3.6e-105
550537004703	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004704	periplasmic chaperone LolA; Region: lolA; TIGR00547
550537004705	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
550537004706	HMMPfam hit to PF03548, Outer membrane lipoprotein carrier protein LolA, score 3.7e-78
550537004707	recombination factor protein RarA; Reviewed; Region: PRK13342
550537004708	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537004709	Walker A motif; other site
550537004710	ATP binding site [chemical binding]; other site
550537004711	Walker B motif; other site
550537004712	arginine finger; other site
550537004713	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
550537004714	HMMPfam hit to PF00004, AAA ATPase, core, score 4.1e-25
550537004715	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004716	seryl-tRNA synthetase; Provisional; Region: PRK05431
550537004717	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
550537004718	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
550537004719	dimer interface [polypeptide binding]; other site
550537004720	active site
550537004721	motif 1; other site
550537004722	motif 2; other site
550537004723	motif 3; other site
550537004724	HMMPfam hit to PF02403, Seryl-tRNA synthetase, class IIa, N-terminal, score 1e-46
550537004725	HMMPfam hit to PF00587, Aminoacyl-tRNA synthetase, class II (G, H, P and S), score 3.4e-68
550537004726	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537004727	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
550537004728	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
550537004729	putative [Fe4-S4] binding site [ion binding]; other site
550537004730	putative molybdopterin cofactor binding site [chemical binding]; other site
550537004731	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
550537004732	putative molybdopterin cofactor binding site; other site
550537004733	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 2e-17
550537004734	PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
550537004735	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 1.3e-185
550537004736	PS00490 Prokaryotic molybdopterin oxidoreductases signature 2.
550537004737	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 2.1e-37
550537004738	PS00932 Prokaryotic molybdopterin oxidoreductases signature 3.
550537004739	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
550537004740	4Fe-4S binding domain; Region: Fer4; pfam00037
550537004741	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004742	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.5e-07
550537004743	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537004744	PS00190 Cytochrome c family heme-binding site signature.
550537004745	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
550537004746	HMMPfam hit to PF04976, DMSO reductase anchor subunit (DmsC), score 9.6e-163
550537004747	8 probable transmembrane helices predicted for SEN0871 by TMHMM2.0 at aa 10-32, 44-66, 88-107, 114-134, 149-171, 178-200, 227-246 and 253-275
550537004748	putative MFS family transporter protein; Provisional; Region: PRK03633
550537004749	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537004750	putative substrate translocation pore; other site
550537004751	12 probable transmembrane helices predicted for SEN0872 by TMHMM2.0 at aa 7-29, 44-66, 73-95, 100-119, 131-150, 160-182, 204-226, 231-253, 265-284, 289-311, 320-342 and 352-369
550537004752	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.6e-25
550537004753	PS00237 G-protein coupled receptors signature.
550537004754	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004755	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537004756	inner membrane transporter YjeM; Provisional; Region: PRK15238
550537004757	HMMPfam hit to PF00324, Amino acid permease-associated region, score 0.0024
550537004758	11 probable transmembrane helices predicted for SEN0873 by TMHMM2.0 at aa 10-29, 36-58, 127-146, 158-180, 195-217, 238-260, 287-309, 340-362, 377-399, 412-434 and 444-466
550537004759	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004760	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
550537004761	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537004762	FeS/SAM binding site; other site
550537004763	HMMPfam hit to PF04055, Radical SAM, score 4e-27
550537004764	PS01087 Radical activating enzymes signature.
550537004765	PS00190 Cytochrome c family heme-binding site signature.
550537004766	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
550537004767	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
550537004768	Pyruvate formate lyase 1; Region: PFL1; cd01678
550537004769	coenzyme A binding site [chemical binding]; other site
550537004770	active site
550537004771	catalytic residues [active]
550537004772	glycine loop; other site
550537004773	HMMPfam hit to PF01228, Formate C-acetyltransferase glycine radical, score 1.8e-63
550537004774	PS00850 Glycine radical signature.
550537004775	HMMPfam hit to PF02901, Pyruvate formate-lyase, PFL, score 0
550537004776	formate transporter; Provisional; Region: PRK10805
550537004777	HMMPfam hit to PF01226, Formate/nitrite transporter, score 4e-176
550537004778	6 probable transmembrane helices predicted for SEN0878 by TMHMM2.0 at aa 35-57, 77-99, 119-141, 161-183, 195-217 and 256-278
550537004779	PS01006 Formate and nitrite transporters signature 2.
550537004780	PS01005 Formate and nitrite transporters signature 1.
550537004781	uncharacterized domain; Region: TIGR00702
550537004782	YcaO-like family; Region: YcaO; pfam02624
550537004783	HMMPfam hit to PF02624, YcaO-like, score 3.4e-160
550537004784	Predicted membrane protein [Function unknown]; Region: COG2323
550537004785	3 probable transmembrane helices predicted for SEN0880 by TMHMM2.0 at aa 15-37, 50-69 and 74-91
550537004786	HMMPfam hit to PF04239, Protein of unknown function DUF421, score 9.3e-26
550537004787	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
550537004788	homodimer interface [polypeptide binding]; other site
550537004789	substrate-cofactor binding pocket; other site
550537004790	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537004791	catalytic residue [active]
550537004792	HMMPfam hit to PF00266, Aminotransferase, class V, score 5.1e-84
550537004793	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
550537004794	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
550537004795	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
550537004796	hinge; other site
550537004797	active site
550537004798	HMMPfam hit to PF00275, 3-phosphoshikimate 1-carboxyvinyltransferase, score 1.8e-223
550537004799	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004800	PS00104 EPSP synthase signature 1.
550537004801	PS00885 EPSP synthase signature 2.
550537004802	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
550537004803	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537004804	HMMPfam hit to PF01435, Peptidase M48, Ste24p, score 2.7e-30
550537004805	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537004806	cytidylate kinase; Provisional; Region: cmk; PRK00023
550537004807	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
550537004808	CMP-binding site; other site
550537004809	The sites determining sugar specificity; other site
550537004810	HMMPfam hit to PF02224, Cytidylate kinase region, score 1.2e-93
550537004811	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
550537004812	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
550537004813	RNA binding site [nucleotide binding]; other site
550537004814	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
550537004815	RNA binding site [nucleotide binding]; other site
550537004816	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
550537004817	RNA binding site [nucleotide binding]; other site
550537004818	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
550537004819	RNA binding site [nucleotide binding]; other site
550537004820	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
550537004821	RNA binding site [nucleotide binding]; other site
550537004822	HMMPfam hit to PF00575, S1, RNA binding, score 1.5e-12
550537004823	HMMPfam hit to PF00575, S1, RNA binding, score 1.2e-17
550537004824	HMMPfam hit to PF00575, S1, RNA binding, score 4e-31
550537004825	HMMPfam hit to PF00575, S1, RNA binding, score 4.2e-30
550537004826	HMMPfam hit to PF00575, S1, RNA binding, score 5.8e-26
550537004827	HMMPfam hit to PF00575, S1, RNA binding, score 2.2e-26
550537004828	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
550537004829	IHF dimer interface [polypeptide binding]; other site
550537004830	IHF - DNA interface [nucleotide binding]; other site
550537004831	HMMPfam hit to PF00216, Histone-like bacterial DNA-binding protein, score 9.2e-47
550537004832	PS00045 Bacterial histone-like DNA-binding proteins signature.
550537004833	ComEC family competence protein; Provisional; Region: PRK11539
550537004834	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
550537004835	Competence protein; Region: Competence; pfam03772
550537004836	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
550537004837	11 probable transmembrane helices predicted for SEN0887 by TMHMM2.0 at aa 5-22, 26-43, 50-69, 224-246, 259-281, 301-323, 328-346, 361-383, 390-412, 427-449 and 469-491
550537004838	HMMPfam hit to PF03772, ComEC/Rec2-related protein, score 8.3e-77
550537004839	HMMPfam hit to PF00753, Beta-lactamase-like, score 1.6e-12
550537004840	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
550537004841	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537004842	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
550537004843	Walker A/P-loop; other site
550537004844	ATP binding site [chemical binding]; other site
550537004845	Q-loop/lid; other site
550537004846	ABC transporter signature motif; other site
550537004847	Walker B; other site
550537004848	D-loop; other site
550537004849	H-loop/switch region; other site
550537004850	5 probable transmembrane helices predicted for SEN0888 by TMHMM2.0 at aa 21-43, 63-94, 140-162, 167-186 and 245-267
550537004851	HMMPfam hit to PF00664, ABC transporter, transmembrane region, score 6.5e-69
550537004852	HMMPfam hit to PF00005, ABC transporter related, score 1.3e-62
550537004853	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004854	PS00211 ABC transporters family signature.
550537004855	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
550537004856	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
550537004857	HMMPfam hit to PF02606, Tetraacyldisaccharide-1-P 4'-kinase, score 5.5e-163
550537004858	1 probable transmembrane helix predicted for SEN0889 by TMHMM2.0 at aa 12-34
550537004859	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
550537004860	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
550537004861	HMMPfam hit to PF06224, Protein of unknown function DUF1006, score 4.3e-259
550537004862	hypothetical protein; Provisional; Region: PRK11827
550537004863	HMMPfam hit to PF03966, Protein of unknown function DUF343, score 1e-14
550537004864	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
550537004865	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
550537004866	Ligand binding site; other site
550537004867	oligomer interface; other site
550537004868	HMMPfam hit to PF02348, Acylneuraminate cytidylyltransferase, score 1.1e-95
550537004869	hypothetical protein; Provisional; Region: PRK10593
550537004870	Uncharacterized conserved protein [Function unknown]; Region: COG1434
550537004871	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
550537004872	putative active site [active]
550537004873	HMMPfam hit to PF02698, Protein of unknown function DUF218, score 5.9e-47
550537004874	2 probable transmembrane helices predicted for SEN0894 by TMHMM2.0 at aa 10-32 and 41-58
550537004875	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
550537004876	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537004877	S-adenosylmethionine binding site [chemical binding]; other site
550537004878	HMMPfam hit to PF08241, Methyltransferase type 11, score 2.6e-20
550537004879	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004880	condesin subunit F; Provisional; Region: PRK05260
550537004881	HMMPfam hit to PF03882, Prokaryotic chromosome segregation and condensation protein MukF, score 0
550537004882	condesin subunit E; Provisional; Region: PRK05256
550537004883	HMMPfam hit to PF04288, Prokaryotic chromosome segregation and condensation protein MukE, score 8.2e-166
550537004884	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
550537004885	P-loop containing region of AAA domain; Region: AAA_29; cl17516
550537004886	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
550537004887	HMMPfam hit to PF04310, Prokaryotic chromosome segregation and condensation protein MukB, N-terminal, score 2.5e-186
550537004888	PS00017 ATP/GTP-binding site motif A (P-loop).
550537004889	murein L,D-transpeptidase; Provisional; Region: PRK10594
550537004890	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
550537004891	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
550537004892	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
550537004893	HMMPfam hit to PF01471, Peptidoglycan binding-like, score 9.7e-10
550537004894	PS00092 N-6 Adenine-specific DNA methylases signature.
550537004895	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537004896	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
550537004897	Peptidase M15; Region: Peptidase_M15_3; cl01194
550537004898	1 probable transmembrane helix predicted for SEN0900 by TMHMM2.0 at aa 12-34
550537004899	HMMPfam hit to PF05951, Protein of unknown function DUF882, bacterial, score 2.9e-106
550537004900	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
550537004901	HMMPfam hit to PF00753, Beta-lactamase-like, score 3.7e-38
550537004902	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
550537004903	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537004904	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537004905	homodimer interface [polypeptide binding]; other site
550537004906	catalytic residue [active]
550537004907	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 1.1e-143
550537004908	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
550537004909	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537004910	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
550537004911	trimer interface [polypeptide binding]; other site
550537004912	eyelet of channel; other site
550537004913	HMMPfam hit to PF00267, Porin, Gram-negative type, score 2.6e-198
550537004914	PS00576 General diffusion Gram-negative porins signature.
550537004915	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
550537004916	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
550537004917	putative dimer interface [polypeptide binding]; other site
550537004918	putative anticodon binding site; other site
550537004919	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
550537004920	homodimer interface [polypeptide binding]; other site
550537004921	motif 1; other site
550537004922	motif 2; other site
550537004923	active site
550537004924	motif 3; other site
550537004925	HMMPfam hit to PF00152, Aminoacyl-tRNA synthetase, class II (D, K and N), score 3.1e-77
550537004926	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537004927	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537004928	HMMPfam hit to PF01336, Nucleic acid binding, OB-fold, tRNA/helicase-type, score 1.1e-19
550537004929	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
550537004930	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537004931	putative DNA binding site [nucleotide binding]; other site
550537004932	putative Zn2+ binding site [ion binding]; other site
550537004933	AsnC family; Region: AsnC_trans_reg; pfam01037
550537004934	HMMPfam hit to PF01037, Bacterial regulatory proteins, AsnC/Lrp, score 1.8e-18
550537004935	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 8.3e-06
550537004936	PS00519 Bacterial regulatory proteins, asnC family signature.
550537004937	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
550537004938	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
550537004939	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537004940	catalytic residue [active]
550537004941	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 8.6e-09
550537004942	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
550537004943	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
550537004944	11 probable transmembrane helices predicted for SEN0907 by TMHMM2.0 at aa 13-35, 76-98, 103-125, 152-174, 189-211, 218-240, 250-272, 314-336, 356-378, 399-418 and 422-439
550537004945	HMMPfam hit to PF01235, Sodium:alanine symporter, score 5e-58
550537004946	PS00873 Sodium:alanine symporter family signature.
550537004947	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
550537004948	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
550537004949	active site
550537004950	HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase-like, score 6.1e-125
550537004951	Remnant of a Gifsy-2 prophage
550537004952	Located within a degenerate Gifsy-2 prophage
550537004953	Located within a degenerate Gifsy-2 prophage
550537004954	HMMPfam hit to PF03837, RecT protein, score 5.8e-10
550537004955	Located within a degenerate Gifsy-2 prophage
550537004956	Located within a degenerate Gifsy-2 prophage
550537004957	Phage Tail Collar Domain; Region: Collar; pfam07484
550537004958	HMMPfam hit to PF07484, Phage Tail Collar, score 2.2e-20
550537004959	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
550537004960	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 2.9e-67
550537004961	Located within a degenerate Gifsy-2 prophage
550537004962	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 7.9e-27
550537004963	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
550537004964	Located within a degenerate Gifsy-2 prophage
550537004965	hypothetical protein; Provisional; Region: PRK09951
550537004966	HMMPfam hit to PF02586, Protein of unknown function DUF159, score 2.5e-43
550537004967	Note the frameshift mutation following codon 18; Located within a degenerate Gifsy-2 prophage
550537004968	DinI-like family; Region: DinI; cl11630
550537004969	HMMPfam hit to PF06183, DinI-like, score 9.3e-06
550537004970	aminopeptidase N; Provisional; Region: pepN; PRK14015
550537004971	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
550537004972	active site
550537004973	Zn binding site [ion binding]; other site
550537004974	HMMPfam hit to PF01433, Peptidase M1, membrane alanine aminopeptidase, N-terminal, score 6.9e-70
550537004975	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537004976	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
550537004977	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
550537004978	quinone interaction residues [chemical binding]; other site
550537004979	active site
550537004980	catalytic residues [active]
550537004981	FMN binding site [chemical binding]; other site
550537004982	substrate binding site [chemical binding]; other site
550537004983	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, core, score 7.1e-105
550537004984	PS00911 Dihydroorotate dehydrogenase signature 1.
550537004985	PS00912 Dihydroorotate dehydrogenase signature 2.
550537004986	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
550537004987	HMMPfam hit to PF07126, Protein of unknown function DUF1379, score 4.2e-121
550537004988	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
550537004989	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
550537004990	MOSC domain; Region: MOSC; pfam03473
550537004991	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
550537004992	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
550537004993	catalytic loop [active]
550537004994	iron binding site [ion binding]; other site
550537004995	HMMPfam hit to PF00111, Ferredoxin, score 2e-19
550537004996	HMMPfam hit to PF03473, Molybdenum cofactor sulphurase, C-terminal, score 4.2e-57
550537004997	HMMPfam hit to PF03476, MOSC, N-terminal beta barrel, score 8.7e-47
550537004998	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537004999	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
550537005000	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
550537005001	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
550537005002	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537005003	S-adenosylmethionine binding site [chemical binding]; other site
550537005004	HMMPfam hit to PF02926, THUMP, score 1.4e-22
550537005005	HMMPfam hit to PF01170,  RNA methylase, score 4.5e-102
550537005006	PS01261 Uncharacterized protein family UPF0020 signature.
550537005007	PS00092 N-6 Adenine-specific DNA methylases signature.
550537005008	HMMPfam hit to PF03602, Conserved hypothetical protein CHP00095, score 0.0034
550537005009	ABC transporter ATPase component; Reviewed; Region: PRK11147
550537005010	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537005011	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537005012	Walker A/P-loop; other site
550537005013	Walker A/P-loop; other site
550537005014	ATP binding site [chemical binding]; other site
550537005015	ATP binding site [chemical binding]; other site
550537005016	Q-loop/lid; other site
550537005017	Q-loop/lid; other site
550537005018	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537005019	ABC transporter signature motif; other site
550537005020	Walker B; other site
550537005021	D-loop; other site
550537005022	ABC transporter; Region: ABC_tran_2; pfam12848
550537005023	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537005024	HMMPfam hit to PF00005, ABC transporter related, score 2.9e-45
550537005025	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005026	PS00211 ABC transporters family signature.
550537005027	HMMPfam hit to PF00005, ABC transporter related, score 1.5e-48
550537005028	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005029	PS00211 ABC transporters family signature.
550537005030	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
550537005031	Paraquat-inducible protein A; Region: PqiA; pfam04403
550537005032	Paraquat-inducible protein A; Region: PqiA; pfam04403
550537005033	HMMPfam hit to PF04403, Paraquat-inducible protein A, score 5.8e-87
550537005034	8 probable transmembrane helices predicted for SEN0928 by TMHMM2.0 at aa 56-78, 100-122, 135-157, 162-184, 255-277, 304-326, 350-372 and 377-399
550537005035	HMMPfam hit to PF04403, Paraquat-inducible protein A, score 1.7e-100
550537005036	paraquat-inducible protein B; Provisional; Region: PRK10807
550537005037	mce related protein; Region: MCE; pfam02470
550537005038	mce related protein; Region: MCE; pfam02470
550537005039	mce related protein; Region: MCE; pfam02470
550537005040	1 probable transmembrane helix predicted for SEN0929 by TMHMM2.0 at aa 16-38
550537005041	HMMPfam hit to PF02470, Mammalian cell entry related, score 5.9e-22
550537005042	HMMPfam hit to PF02470, Mammalian cell entry related, score 0.0036
550537005043	HMMPfam hit to PF02470, Mammalian cell entry related, score 4.9e-16
550537005044	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
550537005045	Protein of unknown function (DUF330); Region: DUF330; pfam03886
550537005046	HMMPfam hit to PF03886, Protein of unknown function DUF330, score 1.8e-90
550537005047	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005048	ribosome modulation factor; Provisional; Region: PRK14563
550537005049	HMMPfam hit to PF04957, Ribosome modulation factor, score 2.5e-41
550537005050	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
550537005051	active site 1 [active]
550537005052	dimer interface [polypeptide binding]; other site
550537005053	active site 2 [active]
550537005054	HMMPfam hit to PF07977, Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ, score 1.2e-76
550537005055	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
550537005056	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
550537005057	HMMPfam hit to PF05362, Peptidase S16, lon C-terminal, score 0.00019
550537005058	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
550537005059	HMMPfam hit to PF06303, Protein of unknown function DUF1047, score 1.8e-116
550537005060	outer membrane protein A; Reviewed; Region: PRK10808
550537005061	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
550537005062	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
550537005063	ligand binding site [chemical binding]; other site
550537005064	HMMPfam hit to PF00691, Outer membrane protein, OmpA/MotB, C-terminal, score 1.7e-47
550537005065	PS01068 OmpA-like domain.
550537005066	HMMPfam hit to PF01389, Outer membrane protein, OmpA-like, transmembrane region, score 4e-121
550537005067	cell division inhibitor SulA; Region: sula; TIGR00623
550537005068	HMMPfam hit to PF03846, Cell division inhibitor SulA, score 2.3e-97
550537005069	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
550537005070	TfoX C-terminal domain; Region: TfoX_C; pfam04994
550537005071	HMMPfam hit to PF04993, TfoX, N-terminal, score 3.4e-07
550537005072	HMMPfam hit to PF04994, TfoX, C-terminal, score 7.5e-34
550537005073	TIGR01666 family membrane protein; Region: YCCS
550537005074	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
550537005075	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
550537005076	HMMPfam hit to PF05976, Protein of unknown function DUF893, YccS/YhfK, score 0
550537005077	7 probable transmembrane helices predicted for SEN0938 by TMHMM2.0 at aa 13-35, 86-108, 115-137, 141-163, 438-460, 484-503 and 510-532
550537005078	PS00217 Sugar transport proteins signature 2.
550537005079	Predicted membrane protein [Function unknown]; Region: COG3304
550537005080	Domain of unknown function (DUF307); Region: DUF307; pfam03733
550537005081	Domain of unknown function (DUF307); Region: DUF307; pfam03733
550537005082	HMMPfam hit to PF03733, Protein of unknown function DUF307, score 9e-32
550537005083	3 probable transmembrane helices predicted for SEN0939 by TMHMM2.0 at aa 15-37, 77-99 and 104-126
550537005084	HMMPfam hit to PF03733, Protein of unknown function DUF307, score 6e-18
550537005085	DNA helicase IV; Provisional; Region: helD; PRK11054
550537005086	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
550537005087	Part of AAA domain; Region: AAA_19; pfam13245
550537005088	Family description; Region: UvrD_C_2; pfam13538
550537005089	HMMPfam hit to PF00580, DNA helicase, UvrD/REP type, score 1.1e-27
550537005090	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005091	HMMPfam hit to PF00580, DNA helicase, UvrD/REP type, score 3e-18
550537005092	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
550537005093	active site
550537005094	dimer interfaces [polypeptide binding]; other site
550537005095	catalytic residues [active]
550537005096	HMMPfam hit to PF02142, MGS-like, score 4e-27
550537005097	PS01335 Methylglyoxal synthase active site.
550537005098	hypothetical protein; Provisional; Region: PRK03641
550537005099	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
550537005100	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
550537005101	HMMPfam hit to PF02629, CoA-binding, score 7.6e-25
550537005102	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005103	heat shock protein HspQ; Provisional; Region: PRK14129
550537005104	HMMPfam hit to PF08755, Hemimethylated DNA-binding region, score 2.9e-48
550537005105	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
550537005106	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
550537005107	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
550537005108	putative RNA binding site [nucleotide binding]; other site
550537005109	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537005110	S-adenosylmethionine binding site [chemical binding]; other site
550537005111	PS00294 Prenyl group binding site (CAAX box).
550537005112	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005113	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005114	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
550537005115	substrate binding site [chemical binding]; other site
550537005116	HMMPfam hit to PF01161, PEBP, score 4.7e-11
550537005117	Cupin domain; Region: Cupin_2; cl17218
550537005118	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537005119	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537005120	PS00041 Bacterial regulatory proteins, araC family signature.
550537005121	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 6.5e-06
550537005122	acylphosphatase; Provisional; Region: PRK14426
550537005123	HMMPfam hit to PF00708, Acylphosphatase, score 7.8e-17
550537005124	PS00150 Acylphosphatase signature 1.
550537005125	PS00151 Acylphosphatase signature 2.
550537005126	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
550537005127	sulfur transfer protein TusE; Provisional; Region: PRK11508
550537005128	HMMPfam hit to PF04358, DsrC-like protein, score 6.4e-79
550537005129	YccA-like proteins; Region: YccA_like; cd10433
550537005130	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
550537005131	HMMPfam hit to PF01027, Protein of unknown function UPF0005, score 1.6e-46
550537005132	6 probable transmembrane helices predicted for SEN0950 by TMHMM2.0 at aa 15-37, 49-71, 76-98, 105-127, 132-154 and 167-189
550537005133	PS01243 Uncharacterized protein family UPF0005 signature.
550537005134	Salmonella Pathogenicity Island 5: SPI-5
550537005135	PipA protein; Region: PipA; pfam07108
550537005136	HMMPfam hit to PF07108, PipA, score 3.9e-183
550537005137	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537005138	secreted effector protein PipB; Provisional; Region: PRK15197
550537005139	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537005140	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537005141	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537005142	HMMPfam hit to PF00805, Pentapeptide repeat, score 1.7
550537005143	HMMPfam hit to PF00805, Pentapeptide repeat, score 1.7e-13
550537005144	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
550537005145	HMMPfam hit to PF00805, Pentapeptide repeat, score 1.8e-08
550537005146	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
550537005147	HMMPfam hit to PF07824, Type III secretion system chaperone, score 1.2e-81
550537005148	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
550537005149	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
550537005150	HMMPfam hit to PF05925, Type III secretion system outer membrane, B protein, score 0
550537005151	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
550537005152	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
550537005153	HMMPfam hit to PF03577, Peptidase C69, dipeptidase A, score 6.7e-235
550537005154	1 probable transmembrane helix predicted for SEN0958 by TMHMM2.0 at aa 5-27
550537005155	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
550537005156	HAMP domain; Region: HAMP; pfam00672
550537005157	dimerization interface [polypeptide binding]; other site
550537005158	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537005159	dimer interface [polypeptide binding]; other site
550537005160	phosphorylation site [posttranslational modification]
550537005161	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537005162	ATP binding site [chemical binding]; other site
550537005163	Mg2+ binding site [ion binding]; other site
550537005164	G-X-G motif; other site
550537005165	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2.5e-28
550537005166	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.1e-14
550537005167	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 3.2e-09
550537005168	2 probable transmembrane helices predicted for SEN0959 by TMHMM2.0 at aa 10-32 and 162-181
550537005169	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005170	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
550537005171	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537005172	active site
550537005173	phosphorylation site [posttranslational modification]
550537005174	intermolecular recognition site; other site
550537005175	dimerization interface [polypeptide binding]; other site
550537005176	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537005177	DNA binding site [nucleotide binding]
550537005178	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 1.3e-26
550537005179	HMMPfam hit to PF00072, Response regulator receiver, score 1.3e-43
550537005180	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
550537005181	active site
550537005182	homotetramer interface [polypeptide binding]; other site
550537005183	1 probable transmembrane helix predicted for SEN0961 by TMHMM2.0 at aa 5-24
550537005184	HMMPfam hit to PF00576, Transthyretin, score 1e-64
550537005185	PS00768 Transthyretin signature 1.
550537005186	PS00769 Transthyretin signature 2.
550537005187	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
550537005188	HMMPfam hit to PF01613, Flavin reductase-like, FMN-binding, score 1.2e-63
550537005189	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
550537005190	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
550537005191	HMMPfam hit to PF03241, 4-hydroxyphenylacetate 3-hydroxylase, score 3.4e-215
550537005192	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
550537005193	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
550537005194	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 4.5e-20
550537005195	PS01117 Bacterial regulatory proteins, marR family signature.
550537005196	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
550537005197	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
550537005198	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
550537005199	HMMPfam hit to PF01557, Fumarylacetoacetase, C-terminal-like, score 1.5e-11
550537005200	HMMPfam hit to PF01557, Fumarylacetoacetase, C-terminal-like, score 2.4e-86
550537005201	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
550537005202	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
550537005203	NAD binding site [chemical binding]; other site
550537005204	catalytic residues [active]
550537005205	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 2.9e-238
550537005206	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537005207	PS00070 Aldehyde dehydrogenases cysteine active site.
550537005208	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
550537005209	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
550537005210	putative active site [active]
550537005211	putative metal binding site [ion binding]; other site
550537005212	HMMPfam hit to PF02900, Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B, score 1.4e-87
550537005213	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
550537005214	putative substrate binding pocket [chemical binding]; other site
550537005215	trimer interface [polypeptide binding]; other site
550537005216	HMMPfam hit to PF02962, 5-carboxymethyl-2-hydroxymuconate isomerase, score 1.1e-99
550537005217	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
550537005218	HMMPfam hit to PF01689, Hydratase/decarboxylase, score 3e-139
550537005219	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
550537005220	HMMPfam hit to PF03328, HpcH/HpaI aldolase, score 5.8e-114
550537005221	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537005222	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
550537005223	putative substrate translocation pore; other site
550537005224	12 probable transmembrane helices predicted for SEN0971 by TMHMM2.0 at aa 32-54, 69-88, 101-123, 133-155, 162-184, 194-216, 270-292, 305-327, 340-357, 361-383, 396-418 and 428-447
550537005225	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.8e-56
550537005226	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
550537005227	Cupin domain; Region: Cupin_2; pfam07883
550537005228	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537005229	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 1.9e-05
550537005230	PS00041 Bacterial regulatory proteins, araC family signature.
550537005231	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 7.6e-08
550537005232	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
550537005233	HMMPfam hit to PF00753, Beta-lactamase-like, score 2e-10
550537005234	anti-adapter protein IraM; Provisional; Region: PRK09919
550537005235	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
550537005236	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
550537005237	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
550537005238	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
550537005239	HSP70 interaction site [polypeptide binding]; other site
550537005240	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
550537005241	substrate binding site [polypeptide binding]; other site
550537005242	dimer interface [polypeptide binding]; other site
550537005243	HMMPfam hit to PF01556, Chaperone DnaJ, C-terminal, score 1.2e-32
550537005244	HMMPfam hit to PF00226, Heat shock protein DnaJ, N-terminal, score 3e-34
550537005245	PS00636 Nt-dnaJ domain signature.
550537005246	2 probable transmembrane helices predicted for SEN0977 by TMHMM2.0 at aa 7-29 and 66-88
550537005247	PS00435 Peroxidases proximal heme-ligand signature.
550537005248	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
550537005249	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
550537005250	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
550537005251	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
550537005252	DsbD alpha interface [polypeptide binding]; other site
550537005253	catalytic residues [active]
550537005254	6 probable transmembrane helices predicted for SEN0978 by TMHMM2.0 at aa 280-302, 323-345, 360-382, 409-431, 436-458 and 479-501
550537005255	HMMPfam hit to PF02683, Cytochrome c biogenesis protein, transmembrane region, score 0.00017
550537005256	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
550537005257	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
550537005258	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
550537005259	catalytic residues [active]
550537005260	HMMPfam hit to PF01323, DSBA oxidoreductase, score 2e-44
550537005261	PS00194 Thioredoxin family active site.
550537005262	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
550537005263	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
550537005264	catalytic residues [active]
550537005265	1 probable transmembrane helix predicted for SEN0980 by TMHMM2.0 at aa 12-29
550537005266	HMMPfam hit to PF00578, Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen, score 1.7e-12
550537005268	HMMPfam hit to PF00328, Histidine acid phosphatase, score 1.3e-60
550537005269	hypothetical protein; Provisional; Region: PRK10174
550537005270	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
550537005271	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
550537005272	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 9.7e-25
550537005273	General stress protein [General function prediction only]; Region: GsiB; COG3729
550537005274	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005275	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
550537005276	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537005277	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
550537005278	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 9.8e-18
550537005279	HMMPfam hit to PF08362, Transcriptional regulator, YcdC, C-terminal, score 1e-89
550537005280	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
550537005281	HMMPfam hit to PF07007, Protein of unknown function DUF1311, score 1.3e-47
550537005282	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
550537005283	Predicted transcriptional regulator [Transcription]; Region: COG3905
550537005284	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
550537005285	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
550537005286	Glutamate binding site [chemical binding]; other site
550537005287	NAD binding site [chemical binding]; other site
550537005288	catalytic residues [active]
550537005289	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 3.3e-103
550537005290	PS00070 Aldehyde dehydrogenases cysteine active site.
550537005291	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537005292	HMMPfam hit to PF01619, Proline dehydrogenase, score 3.4e-193
550537005293	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
550537005294	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
550537005295	Na binding site [ion binding]; other site
550537005296	12 probable transmembrane helices predicted for SEN0987 by TMHMM2.0 at aa 7-26, 66-88, 125-147, 162-184, 191-213, 233-255, 276-298, 313-335, 372-391, 401-423, 428-450 and 455-473
550537005297	HMMPfam hit to PF00474, Na+/solute symporter, score 1.5e-215
550537005298	PS00456 Sodium:solute symporter family signature 1.
550537005299	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005300	PS00457 Sodium:solute symporter family signature 2.
550537005301	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
550537005302	hypothetical protein; Provisional; Region: PRK10536
550537005303	HMMPfam hit to PF02562, PhoH-like protein, score 3.4e-140
550537005304	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005305	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
550537005306	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
550537005307	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
550537005308	putative active site [active]
550537005309	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 8.5e-22
550537005310	HMMPfam hit to PF01418, Helix-turn-helix protein RpiR, score 2.9e-30
550537005311	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
550537005312	Na binding site [ion binding]; other site
550537005313	13 probable transmembrane helices predicted for SEN0989 by TMHMM2.0 at aa 6-28, 41-63, 78-100, 121-143, 158-180, 187-209, 229-248, 280-299, 314-336, 376-398, 403-425, 432-454 and 458-480
550537005314	HMMPfam hit to PF00474, Na+/solute symporter, score 8.4e-10
550537005315	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
550537005316	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
550537005317	putative active site cavity [active]
550537005318	HMMPfam hit to PF04131, N-acetylmannosamine-6-phosphate epimerase, score 4.9e-121
550537005319	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
550537005320	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
550537005321	1 probable transmembrane helix predicted for SEN0991 by TMHMM2.0 at aa 13-32
550537005322	HMMPfam hit to PF01344, Kelch repeat type 1, score 2.8e-09
550537005323	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
550537005324	HMMPfam hit to PF06178, Oligogalacturonate-specific porin, score 2e-124
550537005325	putative sialic acid transporter; Provisional; Region: PRK12307
550537005326	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537005327	putative substrate translocation pore; other site
550537005328	12 probable transmembrane helices predicted for SEN0993 by TMHMM2.0 at aa 20-42, 57-76, 88-110, 114-136, 143-165, 169-188, 230-252, 267-286, 299-316, 321-343, 360-382 and 387-409
550537005329	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.2e-41
550537005330	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
550537005331	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
550537005332	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
550537005333	HMMPfam hit to PF01408, Oxidoreductase, N-terminal, score 1.2e-40
550537005334	PS00044 Bacterial regulatory proteins, lysR family signature.
550537005335	HMMPfam hit to PF02894, Oxidoreductase, C-terminal, score 2.2e-20
550537005336	YCII-related domain; Region: YCII; cl00999
550537005337	HMMPfam hit to PF03795, YCII-related, score 6.5e-20
550537005338	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
550537005339	1 probable transmembrane helix predicted for SEN0998 by TMHMM2.0 at aa 4-26
550537005340	1 probable transmembrane helix predicted for SEN0999 by TMHMM2.0 at aa 5-23
550537005341	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537005342	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 0.00082
550537005343	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
550537005344	HMMPfam hit to PF05638, Virulence factor for secretion apparatus, score 7e-59
550537005345	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
550537005346	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
550537005347	ImpA domain protein; Region: DUF3702; pfam12486
550537005348	1 probable transmembrane helix predicted for SEN1003 by TMHMM2.0 at aa 319-338
550537005349	HMMPfam hit to PF06812, ImpA, N-terminal, score 1.1e-24
550537005350	This CDS appears to have suffered a deletion of the N-terminal; Note the limited similarity to the Legionella pneumophila icmF protein
550537005351	PS00120 Lipases, serine active site.
550537005352	HMMPfam hit to PF06744, Protein of unknown function DUF1215, score 4e-51
550537005353	HMMPfam hit to PF06761, ImcF-related, score 1.6e-127
550537005354	1 probable transmembrane helix predicted for SEN1004 by TMHMM2.0 at aa 124-146
550537005355	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537005356	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
550537005357	1 probable transmembrane helix predicted for SEN1007 by TMHMM2.0 at aa 86-108
550537005358	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537005359	Sel1-like repeats; Region: SEL1; smart00671
550537005360	Sel1-like repeats; Region: SEL1; smart00671
550537005361	1 probable transmembrane helix predicted for SEN1008 by TMHMM2.0 at aa 5-24
550537005362	HMMPfam hit to PF08238, Sel1-like, score 1.4e-08
550537005363	HMMPfam hit to PF08238, Sel1-like, score 5.6e-10
550537005364	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537005365	HMMPfam hit to PF08238, Sel1-like, score 0.002
550537005366	HMMPfam hit to PF08238, Sel1-like, score 0.0046
550537005367	HMMPfam hit to PF08238, Sel1-like, score 0.00048
550537005368	Transposase; Region: HTH_Tnp_1; cl17663
550537005369	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
550537005370	HMMPfam hit to PF01527, Transposase IS3/IS911, score 9.6e-10
550537005371	note the frame shift mutation following codon 142
550537005372	HMMPfam hit to PF00665, Integrase, catalytic core, score 4.8e-49
550537005373	dsRNA-gated channel SID-1; Region: SID-1_RNA_chan; pfam13965
550537005374	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005375	1 probable transmembrane helix predicted for SEN1013A by TMHMM2.0 at aa 2-24
550537005376	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
550537005377	DNA-binding site [nucleotide binding]; DNA binding site
550537005378	RNA-binding motif; other site
550537005379	HMMPfam hit to PF00313, Cold-shock protein, DNA-binding, score 1.5e-42
550537005380	PS00352 'Cold-shock' DNA-binding domain signature.
550537005381	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537005382	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
550537005383	trimer interface [polypeptide binding]; other site
550537005384	eyelet of channel; other site
550537005385	HMMPfam hit to PF00267, Porin, Gram-negative type, score 4e-214
550537005386	PS00576 General diffusion Gram-negative porins signature.
550537005387	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
550537005388	2 probable transmembrane helices predicted for SEN1016 by TMHMM2.0 at aa 19-41 and 61-80
550537005389	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
550537005390	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
550537005391	Zn2+ binding site [ion binding]; other site
550537005392	Mg2+ binding site [ion binding]; other site
550537005393	HMMPfam hit to PF01966, Metal-dependent phosphohydrolase, HD region, subdomain, score 6.1e-12
550537005394	DNA cytosine methylase; Provisional; Region: PRK10458
550537005395	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
550537005396	cofactor binding site; other site
550537005397	DNA binding site [nucleotide binding]
550537005398	substrate interaction site [chemical binding]; other site
550537005399	HMMPfam hit to PF00145, C-5 cytosine-specific DNA methylase, score 5.9e-83
550537005400	PS00094 C-5 cytosine-specific DNA methylases active site.
550537005401	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
550537005402	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
550537005403	additional DNA contacts [nucleotide binding]; other site
550537005404	mismatch recognition site; other site
550537005405	active site
550537005406	zinc binding site [ion binding]; other site
550537005407	DNA intercalation site [nucleotide binding]; other site
550537005408	HMMPfam hit to PF03852, DNA mismatch endonuclease vsr, score 8.1e-39
550537005409	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
550537005410	EamA-like transporter family; Region: EamA; pfam00892
550537005411	EamA-like transporter family; Region: EamA; pfam00892
550537005412	10 probable transmembrane helices predicted for SEN1020 by TMHMM2.0 at aa 7-29, 39-57, 69-87, 97-119, 126-145, 149-168, 175-197, 212-234, 241-260 and 270-292
550537005413	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 1.8e-16
550537005414	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2e-28
550537005415	hypothetical protein; Provisional; Region: PRK10062
550537005416	HMMPfam hit to PF05661, Protein of unknown function DUF808, score 4.6e-185
550537005417	5 probable transmembrane helices predicted for SEN1021 by TMHMM2.0 at aa 78-100, 150-169, 173-195, 230-252 and 267-289
550537005418	Uncharacterized small protein [Function unknown]; Region: COG5475
550537005419	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
550537005420	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537005421	metal binding site [ion binding]; metal-binding site
550537005422	active site
550537005423	I-site; other site
550537005424	2 probable transmembrane helices predicted for SEN1023 by TMHMM2.0 at aa 20-42 and 358-380
550537005425	HMMPfam hit to PF00990, GGDEF, score 1.2e-66
550537005426	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
550537005427	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537005428	active site
550537005429	motif I; other site
550537005430	motif II; other site
550537005431	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 5.1e-09
550537005432	PS01228 Hypothetical cof family signature 1.
550537005433	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
550537005434	hypothetical protein; Provisional; Region: PRK10708
550537005435	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
550537005436	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537005437	DNA binding residues [nucleotide binding]
550537005438	dimerization interface [polypeptide binding]; other site
550537005439	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1e-21
550537005440	PS00622 Bacterial regulatory proteins, luxR family signature.
550537005441	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
550537005442	HMMPfam hit to PF01311, Type III secretion system inner membrane R protein, score 4.7e-95
550537005443	6 probable transmembrane helices predicted for SEN1028 by TMHMM2.0 at aa 15-34, 41-58, 73-95, 132-154, 179-201 and 214-236
550537005444	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
550537005445	HMMPfam hit to PF01313, Bacterial export protein FliQ, family 3, score 2.6e-43
550537005446	2 probable transmembrane helices predicted for SEN1029 by TMHMM2.0 at aa 20-42 and 52-74
550537005447	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
550537005448	HMMPfam hit to PF00813, Type III secretion system inner membrane P protein, score 3.3e-125
550537005449	3 probable transmembrane helices predicted for SEN1030 by TMHMM2.0 at aa 29-46, 126-148 and 155-177
550537005450	PS01061 Flagella transport protein fliP family signature 2.
550537005451	PS01060 Flagella transport protein fliP family signature 1.
550537005452	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
550537005453	HMMPfam hit to PF04347, Flagellar biosynthesis protein, FliO, score 2.4e-46
550537005454	1 probable transmembrane helix predicted for SEN1031 by TMHMM2.0 at aa 18-40
550537005455	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
550537005456	flagellar motor switch protein; Validated; Region: fliN; PRK05698
550537005457	HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) protein, score 2.8e-36
550537005458	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
550537005459	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
550537005460	HMMPfam hit to PF02154, Flagellar motor switch protein FliM, score 3.3e-124
550537005461	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
550537005462	HMMPfam hit to PF03748, Flagellar basal body-associated protein FliL, score 7.5e-53
550537005463	1 probable transmembrane helix predicted for SEN1034 by TMHMM2.0 at aa 13-35
550537005464	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005465	flagellar hook-length control protein; Provisional; Region: PRK10118
550537005466	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
550537005467	HMMPfam hit to PF02120, Flagellar hook-length control protein, score 1.1e-52
550537005468	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005469	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
550537005470	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
550537005471	HMMPfam hit to PF02050, Flagellar FliJ protein, score 8.3e-125
550537005472	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
550537005473	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
550537005474	Walker A motif/ATP binding site; other site
550537005475	Walker B motif; other site
550537005476	HMMPfam hit to PF00006, ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding, score 1.3e-122
550537005477	PS00152 ATP synthase alpha and beta subunits signature.
550537005478	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005479	flagellar assembly protein H; Validated; Region: fliH; PRK05687
550537005480	Flagellar assembly protein FliH; Region: FliH; pfam02108
550537005481	HMMPfam hit to PF02108, Flagellar assembly protein FliH, score 3.1e-126
550537005482	flagellar motor switch protein FliG; Region: fliG; TIGR00207
550537005483	FliG C-terminal domain; Region: FliG_C; pfam01706
550537005484	HMMPfam hit to PF01706, Flagellar motor switch protein FliG, score 1.9e-62
550537005485	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
550537005486	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
550537005487	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
550537005488	2 probable transmembrane helices predicted for SEN1040 by TMHMM2.0 at aa 26-45 and 454-476
550537005489	HMMPfam hit to PF08345, Flagellar M-ring C-terminal, score 3.4e-88
550537005490	HMMPfam hit to PF01514, Secretory protein YscJ/FliF, score 1.1e-93
550537005491	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
550537005492	HMMPfam hit to PF02049, Flagellar hook-basal body complex protein FliE, score 2.1e-48
550537005493	1 probable transmembrane helix predicted for SEN1041A by TMHMM2.0 at aa 19-41
550537005494	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
550537005495	CPxP  motif; other site
550537005496	HMMPfam hit to PF01206, SirA-like, score 5.2e-43
550537005497	PS01148 Uncharacterized protein family UPF0033 signature.
550537005498	putative inner membrane protein; Provisional; Region: PRK11099
550537005499	Sulphur transport; Region: Sulf_transp; pfam04143
550537005500	10 probable transmembrane helices predicted for SEN1043 by TMHMM2.0 at aa 30-52, 97-119, 132-151, 166-188, 217-234, 244-266, 279-301, 306-328, 341-360 and 380-402
550537005501	HMMPfam hit to PF04143, Protein of unknown function DUF395, YeeE/YedE, score 3.6e-22
550537005502	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005503	HMMPfam hit to PF04143, Protein of unknown function DUF395, YeeE/YedE, score 6.6e-19
550537005504	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005505	lipoprotein; Provisional; Region: PRK10397
550537005506	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005507	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
550537005508	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
550537005509	active site
550537005510	Na/Ca binding site [ion binding]; other site
550537005511	catalytic site [active]
550537005512	HMMPfam hit to PF02806, Alpha-amylase, C-terminal all beta, score 0.00072
550537005513	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 4.9e-89
550537005514	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
550537005515	HMMPfam hit to PF05400, Flagellar export chaperone, score 3e-81
550537005516	flagellar protein FliS; Validated; Region: fliS; PRK05685
550537005517	HMMPfam hit to PF02561, Flagellar protein FliS, score 1.2e-52
550537005518	flagellar capping protein; Reviewed; Region: fliD; PRK08032
550537005519	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
550537005520	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
550537005521	HMMPfam hit to PF07195, Flagellar hook-associated 2, C-terminal, score 1.6e-79
550537005522	HMMPfam hit to PF07196, Flagellin hook IN, score 5.4e-11
550537005523	HMMPfam hit to PF02465, Flagellar hook-associated protein 2, N-terminal, score 1.3e-30
550537005524	flagellin; Validated; Region: PRK08026
550537005525	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
550537005526	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
550537005527	HMMPfam hit to PF00669, Flagellin, N-terminal, score 4.1e-81
550537005528	HMMPfam hit to PF00700, Flagellin, C-terminal, score 8.4e-40
550537005529	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
550537005530	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
550537005531	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
550537005532	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
550537005533	DNA binding residues [nucleotide binding]
550537005534	HMMPfam hit to PF04542, RNA polymerase sigma-70 region 2, score 5.2e-19
550537005535	PS00715 Sigma-70 factors family signature 1.
550537005536	HMMPfam hit to PF04539, RNA polymerase sigma-70 region 3, score 9.4e-22
550537005537	HMMPfam hit to PF04545, RNA polymerase sigma-70 region 4, score 5.6e-20
550537005538	PS00716 Sigma-70 factors family signature 2.
550537005539	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
550537005540	HMMPfam hit to PF02899, Integrase, N-terminal SAM-like, phage, score 4.8e-17
550537005541	cystine transporter subunit; Provisional; Region: PRK11260
550537005542	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537005543	substrate binding pocket [chemical binding]; other site
550537005544	membrane-bound complex binding site; other site
550537005545	hinge residues; other site
550537005546	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 2.1e-104
550537005547	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537005548	D-cysteine desulfhydrase; Validated; Region: PRK03910
550537005549	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
550537005550	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537005551	catalytic residue [active]
550537005552	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 1.6e-08
550537005553	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537005554	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537005555	dimer interface [polypeptide binding]; other site
550537005556	conserved gate region; other site
550537005557	putative PBP binding loops; other site
550537005558	ABC-ATPase subunit interface; other site
550537005559	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.5e-35
550537005560	3 probable transmembrane helices predicted for SEN1055 by TMHMM2.0 at aa 20-42, 54-76 and 185-207
550537005561	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537005562	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
550537005563	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
550537005564	Walker A/P-loop; other site
550537005565	ATP binding site [chemical binding]; other site
550537005566	Q-loop/lid; other site
550537005567	ABC transporter signature motif; other site
550537005568	Walker B; other site
550537005569	D-loop; other site
550537005570	H-loop/switch region; other site
550537005571	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
550537005572	HMMPfam hit to PF00005, ABC transporter related, score 2.3e-72
550537005573	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005574	PS00211 ABC transporters family signature.
550537005575	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 1.3e-05
550537005576	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
550537005577	Autoinducer binding domain; Region: Autoind_bind; pfam03472
550537005578	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537005579	DNA binding residues [nucleotide binding]
550537005580	dimerization interface [polypeptide binding]; other site
550537005581	HMMPfam hit to PF03472, Autoinducer-binding, score 3.2e-52
550537005582	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1.4e-24
550537005583	PS00622 Bacterial regulatory proteins, luxR family signature.
550537005584	hypothetical protein; Provisional; Region: PRK10613
550537005585	response regulator; Provisional; Region: PRK09483
550537005586	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537005587	active site
550537005588	phosphorylation site [posttranslational modification]
550537005589	intermolecular recognition site; other site
550537005590	dimerization interface [polypeptide binding]; other site
550537005591	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537005592	DNA binding residues [nucleotide binding]
550537005593	dimerization interface [polypeptide binding]; other site
550537005594	HMMPfam hit to PF00072, Response regulator receiver, score 3.4e-45
550537005595	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 5.3e-27
550537005596	PS00622 Bacterial regulatory proteins, luxR family signature.
550537005597	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
550537005598	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
550537005599	GIY-YIG motif/motif A; other site
550537005600	active site
550537005601	catalytic site [active]
550537005602	putative DNA binding site [nucleotide binding]; other site
550537005603	metal binding site [ion binding]; metal-binding site
550537005604	UvrB/uvrC motif; Region: UVR; pfam02151
550537005605	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
550537005606	Helix-hairpin-helix motif; Region: HHH; pfam00633
550537005607	HMMPfam hit to PF01541, Excinuclease ABC, C subunit, N-terminal, score 1.2e-32
550537005608	HMMPfam hit to PF02151, UvrB/UvrC protein, score 8.7e-12
550537005609	HMMPfam hit to PF08459, Excinuclease ABC, C subunit, C-terminal, score 5.6e-90
550537005610	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 5.8e-07
550537005611	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 4.9e-07
550537005612	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
550537005613	4 probable transmembrane helices predicted for SEN1061 by TMHMM2.0 at aa 7-29, 33-52, 121-143 and 147-169
550537005614	HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 3.9e-48
550537005615	PS00379 CDP-alcohol phosphatidyltransferases signature.
550537005616	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005617	Note the frameshift mutation following codon 44
550537005618	1 probable transmembrane helix predicted for SEN1063 by TMHMM2.0 at aa 26-48
550537005619	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
550537005620	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
550537005621	NlpC/P60 family; Region: NLPC_P60; cl17555
550537005622	HMMPfam hit to PF00877, NLP/P60, score 0.00026
550537005623	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
550537005624	hypothetical protein; Provisional; Region: PRK10396
550537005625	yecA family protein; Region: ygfB_yecA; TIGR02292
550537005626	SEC-C motif; Region: SEC-C; pfam02810
550537005627	HMMPfam hit to PF02810, SEC-C motif, score 7.8e-07
550537005628	PS00294 Prenyl group binding site (CAAX box).
550537005629	tyrosine transporter TyrP; Provisional; Region: PRK15132
550537005630	aromatic amino acid transport protein; Region: araaP; TIGR00837
550537005631	11 probable transmembrane helices predicted for SEN1068 by TMHMM2.0 at aa 7-29, 33-55, 81-103, 113-135, 148-167, 182-204, 216-235, 273-295, 308-330, 335-357 and 377-399
550537005632	HMMPfam hit to PF03222, Aromatic amino acid permease, score 1.4e-202
550537005633	PS00594 Aromatic amino acids permeases signature.
550537005634	probable metal-binding protein; Region: matur_matur; TIGR03853
550537005635	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
550537005636	Ferritin-like domain; Region: Ferritin; pfam00210
550537005637	ferroxidase diiron center [ion binding]; other site
550537005638	HMMPfam hit to PF00210, Ferritin and Dps, score 3.9e-45
550537005639	YecR-like lipoprotein; Region: YecR; pfam13992
550537005640	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005641	hypothetical protein; Provisional; Region: PRK09273
550537005642	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
550537005643	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
550537005644	HMMPfam hit to PF02502, Ribose/galactose isomerase, score 6.1e-37
550537005645	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
550537005646	Ferritin-like domain; Region: Ferritin; pfam00210
550537005647	ferroxidase diiron center [ion binding]; other site
550537005648	HMMPfam hit to PF00210, Ferritin and Dps, score 4.6e-21
550537005649	DJ-1 family protein; Region: not_thiJ; TIGR01383
550537005650	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
550537005651	conserved cys residue [active]
550537005652	HMMPfam hit to PF01965, ThiJ/PfpI, score 3.1e-22
550537005653	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
550537005654	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
550537005655	HMMPfam hit to PF02358, Trehalose-phosphatase, score 4.4e-73
550537005656	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
550537005657	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
550537005658	active site
550537005659	homotetramer interface [polypeptide binding]; other site
550537005660	HMMPfam hit to PF00982, Glycosyl transferase, family 20, score 1e-207
550537005661	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
550537005662	Ligand Binding Site [chemical binding]; other site
550537005663	HMMPfam hit to PF00582, UspA, score 4.2e-11
550537005664	transcriptional activator FlhD; Provisional; Region: PRK02909
550537005665	HMMPfam hit to PF05247, Flagellar transcriptional activator, score 9.3e-78
550537005666	transcriptional activator FlhC; Provisional; Region: PRK12722
550537005667	HMMPfam hit to PF05280, Flagellar transcriptional activator FlhC, score 2.4e-160
550537005668	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005669	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
550537005670	flagellar motor protein MotA; Validated; Region: PRK09110
550537005671	3 probable transmembrane helices predicted for SEN1080 by TMHMM2.0 at aa 10-32, 152-171 and 186-208
550537005672	PS01307 Flagellar motor protein motA family signature.
550537005673	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
550537005674	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
550537005675	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
550537005676	ligand binding site [chemical binding]; other site
550537005677	1 probable transmembrane helix predicted for SEN1081 by TMHMM2.0 at aa 29-51
550537005678	HMMPfam hit to PF00691, Outer membrane protein, OmpA/MotB, C-terminal, score 3.1e-36
550537005679	chemotaxis protein CheA; Provisional; Region: PRK10547
550537005680	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
550537005681	putative binding surface; other site
550537005682	active site
550537005683	CheY binding; Region: CheY-binding; pfam09078
550537005684	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
550537005685	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537005686	ATP binding site [chemical binding]; other site
550537005687	Mg2+ binding site [ion binding]; other site
550537005688	G-X-G motif; other site
550537005689	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
550537005690	HMMPfam hit to PF01627, Hpt, score 2.6e-16
550537005691	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
550537005692	HMMPfam hit to PF09078, CheY binding, score 2.6e-30
550537005693	HMMPfam hit to PF02895, Signal transducing histidine kinase, homodimeric, score 4.1e-29
550537005694	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 5e-29
550537005695	HMMPfam hit to PF01584, CheW-like protein, score 4.5e-27
550537005696	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
550537005697	putative CheA interaction surface; other site
550537005698	HMMPfam hit to PF01584, CheW-like protein, score 2.8e-34
550537005699	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
550537005700	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
550537005701	dimer interface [polypeptide binding]; other site
550537005702	ligand binding site [chemical binding]; other site
550537005703	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537005704	dimerization interface [polypeptide binding]; other site
550537005705	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537005706	dimer interface [polypeptide binding]; other site
550537005707	putative CheW interface [polypeptide binding]; other site
550537005708	2 probable transmembrane helices predicted for SEN1084 by TMHMM2.0 at aa 10-32 and 194-216
550537005709	HMMPfam hit to PF02203, Ligand binding Tar, score 1.8e-56
550537005710	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 5.5e-19
550537005711	PS00538 Bacterial chemotaxis sensory transducers signature.
550537005712	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 2.4e-120
550537005713	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
550537005714	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
550537005715	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537005716	S-adenosylmethionine binding site [chemical binding]; other site
550537005717	HMMPfam hit to PF03705, MCP methyltransferase, CheR-type, score 6.2e-17
550537005718	HMMPfam hit to PF01739, MCP methyltransferase, CheR-type, score 1.3e-90
550537005719	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
550537005720	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537005721	active site
550537005722	phosphorylation site [posttranslational modification]
550537005723	intermolecular recognition site; other site
550537005724	dimerization interface [polypeptide binding]; other site
550537005725	CheB methylesterase; Region: CheB_methylest; pfam01339
550537005726	HMMPfam hit to PF00072, Response regulator receiver, score 2.7e-33
550537005727	HMMPfam hit to PF01339, Chemotaxis response regulator protein-glutamate methylesterase, score 2.3e-132
550537005728	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
550537005729	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537005730	active site
550537005731	phosphorylation site [posttranslational modification]
550537005732	intermolecular recognition site; other site
550537005733	dimerization interface [polypeptide binding]; other site
550537005734	HMMPfam hit to PF00072, Response regulator receiver, score 9.7e-48
550537005735	chemotaxis regulator CheZ; Provisional; Region: PRK11166
550537005736	HMMPfam hit to PF04344, Chemotaxis phosphatase, CheZ, score 5e-150
550537005737	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
550537005738	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
550537005739	HMMPfam hit to PF01312, Type III secretion exporter, score 6.6e-183
550537005740	4 probable transmembrane helices predicted for SEN1089 by TMHMM2.0 at aa 33-50, 93-115, 146-168 and 189-211
550537005741	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005742	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
550537005743	FHIPEP family; Region: FHIPEP; pfam00771
550537005744	7 probable transmembrane helices predicted for SEN1090 by TMHMM2.0 at aa 21-43, 47-64, 76-98, 118-140, 213-235, 250-272 and 293-315
550537005745	HMMPfam hit to PF00771, Bacterial type III secretion FHIPEP, score 0
550537005746	PS00994 Bacterial export FHIPEP family signature.
550537005747	Flagellar protein FlhE; Region: FlhE; pfam06366
550537005748	HMMPfam hit to PF06366, Flagellar FlhE, score 2.5e-91
550537005749	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
550537005750	HMMPfam hit to PF07470, Glycosyl hydrolase, family 88, score 1.3e-166
550537005751	penicillin-binding protein 2; Provisional; Region: PRK10795
550537005752	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
550537005753	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
550537005754	HMMPfam hit to PF00905, Penicillin-binding protein, transpeptidase, score 4.4e-78
550537005755	HMMPfam hit to PF03717, Penicillin-binding protein, dimerisation domain, score 2.1e-60
550537005756	1 probable transmembrane helix predicted for SEN1093 by TMHMM2.0 at aa 12-34
550537005757	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
550537005758	arginyl-tRNA synthetase; Region: argS; TIGR00456
550537005759	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
550537005760	active site
550537005761	HIGH motif; other site
550537005762	KMSK motif region; other site
550537005763	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
550537005764	tRNA binding surface [nucleotide binding]; other site
550537005765	anticodon binding site; other site
550537005766	HMMPfam hit to PF05746, DALR anticodon binding, score 1.7e-52
550537005767	HMMPfam hit to PF00750, Arginyl-tRNA synthetase, class Ic, core, score 2.6e-212
550537005768	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537005769	HMMPfam hit to PF03485, Arginyl tRNA synthetase, class Ic, N-terminal, score 2.5e-31
550537005770	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
550537005771	putative metal binding site [ion binding]; other site
550537005772	PS00414 Profilin signature.
550537005773	HMMPfam hit to PF06185, Protein of unknown function DUF991, score 3.2e-111
550537005774	copper homeostasis protein CutC; Provisional; Region: PRK11572
550537005775	HMMPfam hit to PF03932, CutC, score 9.5e-119
550537005776	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537005777	S-adenosylmethionine binding site [chemical binding]; other site
550537005778	HMMPfam hit to PF08003, Methyltransferase, , score 6.6e-251
550537005779	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537005780	S-adenosylmethionine binding site [chemical binding]; other site
550537005781	HMMPfam hit to PF08242, Methyltransferase type 12, score 6e-11
550537005782	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
550537005783	4 probable transmembrane helices predicted for SEN1099 by TMHMM2.0 at aa 4-22, 43-62, 72-89 and 102-124
550537005784	hypothetical protein; Provisional; Region: PRK10302
550537005785	HMMPfam hit to PF01904, Protein of unknown function DUF72, score 1.1e-81
550537005786	Isochorismatase family; Region: Isochorismatase; pfam00857
550537005787	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
550537005788	catalytic triad [active]
550537005789	conserved cis-peptide bond; other site
550537005790	HMMPfam hit to PF00857, Isochorismatase hydrolase, score 7.3e-75
550537005791	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
550537005792	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
550537005793	dimer interface [polypeptide binding]; other site
550537005794	anticodon binding site; other site
550537005795	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
550537005796	homodimer interface [polypeptide binding]; other site
550537005797	motif 1; other site
550537005798	active site
550537005799	motif 2; other site
550537005800	GAD domain; Region: GAD; pfam02938
550537005801	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
550537005802	active site
550537005803	motif 3; other site
550537005804	HMMPfam hit to PF01336, Nucleic acid binding, OB-fold, tRNA/helicase-type, score 2.3e-27
550537005805	HMMPfam hit to PF00152, Aminoacyl-tRNA synthetase, class II (D, K and N), score 2.6e-215
550537005806	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537005807	HMMPfam hit to PF02938, GAD, score 1.3e-52
550537005808	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537005809	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
550537005810	nudix motif; other site
550537005811	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 9.2e-30
550537005812	PS00893 mutT domain signature.
550537005813	hypothetical protein; Validated; Region: PRK00110
550537005814	HMMPfam hit to PF01709, Protein of unknown function DUF28, score 7.9e-151
550537005815	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
550537005816	active site
550537005817	putative DNA-binding cleft [nucleotide binding]; other site
550537005818	dimer interface [polypeptide binding]; other site
550537005819	HMMPfam hit to PF02075, Crossover junction endodeoxyribonuclease RuvC, score 6e-104
550537005820	PS01321 Crossover junction endodeoxyribonuclease ruvC signature.
550537005821	hypothetical protein; Provisional; Region: PRK11470
550537005822	HMMPfam hit to PF06520, Protein of unknown function DUF1105, score 3.5e-136
550537005823	4 probable transmembrane helices predicted for SEN1107 by TMHMM2.0 at aa 9-28, 43-62, 69-88 and 115-137
550537005824	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
550537005825	RuvA N terminal domain; Region: RuvA_N; pfam01330
550537005826	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
550537005827	HMMPfam hit to PF01330, DNA helicase, Holliday junction RuvA type, domain I, bacterial, score 4.3e-29
550537005828	HMMPfam hit to PF07499, DNA helicase, Holliday junction RuvA type, C-terminal domain III, score 1.7e-16
550537005829	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
550537005830	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537005831	Walker A motif; other site
550537005832	ATP binding site [chemical binding]; other site
550537005833	Walker B motif; other site
550537005834	arginine finger; other site
550537005835	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
550537005836	HMMPfam hit to PF05496, DNA helicase, Holliday junction RuvB type, N-terminal, score 1e-07
550537005837	HMMPfam hit to PF00004, AAA ATPase, core, score 1.1e-35
550537005838	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005839	HMMPfam hit to PF05491, DNA helicase, Holliday junction RuvB type, C-terminal, score 3.9e-55
550537005840	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
550537005841	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537005842	ABC-ATPase subunit  interface; other site
550537005843	dimer interface [polypeptide binding]; other site
550537005844	putative PBP binding regions; other site
550537005845	HMMPfam hit to PF00950, ABC-3, score 1.3e-124
550537005846	7 probable transmembrane helices predicted for SEN1110 by TMHMM2.0 at aa 5-27, 48-70, 85-107, 127-145, 170-192, 213-235 and 239-256
550537005847	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005848	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
550537005849	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
550537005850	HMMPfam hit to PF00005, ABC transporter related, score 2.9e-47
550537005851	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005852	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
550537005853	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
550537005854	metal binding site [ion binding]; metal-binding site
550537005855	HMMPfam hit to PF01297, Periplasmic solute binding protein, score 1.1e-34
550537005856	putative peptidase; Provisional; Region: PRK11649
550537005857	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
550537005858	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537005859	Peptidase family M23; Region: Peptidase_M23; pfam01551
550537005860	HMMPfam hit to PF08525, Opacity-associated protein A, N-terminal, score 3.6e-07
550537005861	1 probable transmembrane helix predicted for SEN1113 by TMHMM2.0 at aa 21-40
550537005862	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 3.8e-06
550537005863	HMMPfam hit to PF01551, Peptidase M23B, score 6e-59
550537005864	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
550537005865	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
550537005866	putative acyl-acceptor binding pocket; other site
550537005867	HMMPfam hit to PF03279, Bacterial lipid A biosynthesis acyltransferase, score 4.1e-157
550537005868	1 probable transmembrane helix predicted for SEN1114 by TMHMM2.0 at aa 21-43
550537005869	pyruvate kinase; Provisional; Region: PRK05826
550537005870	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
550537005871	domain interfaces; other site
550537005872	active site
550537005873	HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta, score 4.9e-60
550537005874	HMMPfam hit to PF00224, Pyruvate kinase, barrel, score 1.1e-225
550537005875	PS00110 Pyruvate kinase active site signature.
550537005876	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
550537005877	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
550537005878	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
550537005879	putative active site [active]
550537005880	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 8.4e-38
550537005881	HMMPfam hit to PF01418, Helix-turn-helix protein RpiR, score 1.1e-53
550537005882	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
550537005883	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
550537005884	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
550537005885	HMMPfam hit to PF00479, Glucose-6-phosphate dehydrogenase, score 6.6e-104
550537005886	PS00069 Glucose-6-phosphate dehydrogenase active site.
550537005887	HMMPfam hit to PF02781, Glucose-6-phosphate dehydrogenase, score 3.3e-204
550537005888	phosphogluconate dehydratase; Validated; Region: PRK09054
550537005889	6-phosphogluconate dehydratase; Region: edd; TIGR01196
550537005890	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005891	HMMPfam hit to PF00920, Dihydroxy-acid and 6-phosphogluconate dehydratase, score 9.1e-283
550537005892	PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.
550537005893	PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2.
550537005894	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
550537005895	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
550537005896	active site
550537005897	intersubunit interface [polypeptide binding]; other site
550537005898	catalytic residue [active]
550537005899	HMMPfam hit to PF01081, KDPG and KHG aldolase, score 2.9e-137
550537005900	PS00159 KDPG and KHG aldolases active site.
550537005901	PS00160 KDPG and KHG aldolases Schiff-base forming residue.
550537005902	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
550537005903	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
550537005904	ATP-grasp domain; Region: ATP-grasp; pfam02222
550537005905	HMMPfam hit to PF02222, ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type, score 3.1e-101
550537005906	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
550537005907	HMMPfam hit to PF07130, YebG, score 1.5e-49
550537005908	hypothetical protein; Provisional; Region: PRK13680
550537005909	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
550537005910	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
550537005911	putative metal binding site [ion binding]; other site
550537005912	HMMPfam hit to PF04391, Protein of unknown function DUF533, score 3.4e-102
550537005913	1 probable transmembrane helix predicted for SEN1123 by TMHMM2.0 at aa 52-74
550537005914	protease 2; Provisional; Region: PRK10115
550537005915	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
550537005916	HMMPfam hit to PF02897, Peptidase S9A, oligopeptidase, N-terminal beta-propeller, score 9.9e-155
550537005917	HMMPfam hit to PF00326, Peptidase S9, prolyl oligopeptidase active site region, score 6.4e-103
550537005918	PS00708 Prolyl endopeptidase family serine active site.
550537005919	exodeoxyribonuclease X; Provisional; Region: PRK07983
550537005920	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
550537005921	active site
550537005922	catalytic site [active]
550537005923	substrate binding site [chemical binding]; other site
550537005924	HMMPfam hit to PF00929, Exonuclease, RNase T and DNA polymerase III, score 4.2e-21
550537005925	Predicted amidohydrolase [General function prediction only]; Region: COG0388
550537005926	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
550537005927	HMMPfam hit to PF00795, Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, score 2.1e-07
550537005928	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005929	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
550537005930	HMMPfam hit to PF06440, DNA polymerase III-theta, bacterial, score 5.6e-51
550537005931	hypothetical protein; Provisional; Region: PRK10301
550537005932	HMMPfam hit to PF04234, Copper resistance protein CopC, core, score 1.2e-56
550537005933	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
550537005934	PS00430 TonB-dependent receptor proteins signature 1.
550537005935	HMMPfam hit to PF05425, Copper resistance D, score 4.5e-136
550537005936	8 probable transmembrane helices predicted for SEN1129 by TMHMM2.0 at aa 10-32, 52-74, 94-113, 120-137, 152-174, 195-217, 227-249 and 270-288
550537005937	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005938	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
550537005939	Gifsy-2-like prophage remnant; carries the Type III secreted effector protein SopE as well as pipA, ompX and sodCI
550537005940	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
550537005941	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
550537005942	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
550537005943	dimer interface [polypeptide binding]; other site
550537005944	active site
550537005945	Int/Topo IB signature motif; other site
550537005946	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 6.4e-07
550537005947	HMMPfam hit to PF09003, Integrase, lambda-type, N-terminal DNA-binding, score 2.2e-27
550537005948	Excisionase-like protein; Region: Exc; pfam07825
550537005949	HMMPfam hit to PF07825, Excisionase-like, score 5e-11
550537005950	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
550537005951	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
550537005952	HMMPfam hit to PF00753, Beta-lactamase-like, score 7.5e-14
550537005953	1 probable transmembrane helix predicted for SEN1134 by TMHMM2.0 at aa 13-32
550537005954	1 probable transmembrane helix predicted for SEN1135 by TMHMM2.0 at aa 23-45
550537005955	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
550537005956	HMMPfam hit to PF07105, Protein of unknown function DUF1367, score 3.3e-142
550537005957	The CDS has suffered a deletion removing the majority of the 5' end of this CDS
550537005958	HMMPfam hit to PF05766, Bacteriophage Lambda NinG, score 1.9e-19
550537005959	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005960	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
550537005961	HMMPfam hit to PF06323, Phage antitermination Q, score 1.8e-138
550537005962	This CDS has been subject to a deletion event the remaining CDS represents the very 5' end of a gene highly conserved with bacteriophage Gifsy-2
550537005963	1 probable transmembrane helix predicted for SEN1142 by TMHMM2.0 at aa 9-31
550537005964	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537005965	PipA protein; Region: PipA; pfam07108
550537005966	HMMPfam hit to PF07108, PipA, score 1.1e-188
550537005967	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537005968	phage holin, lambda family; Region: holin_lambda; TIGR01594
550537005969	HMMPfam hit to PF05106, Holin, phage lambda, score 9.6e-28
550537005970	2 probable transmembrane helices predicted for SEN1144 by TMHMM2.0 at aa 21-43 and 70-92
550537005971	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
550537005972	catalytic residues [active]
550537005973	HMMPfam hit to PF00959, Glycoside hydrolase, family 24, score 6.3e-33
550537005974	Signal peptide predicted for SEN1146 by SignalP 2.0 HMM (Signal peptide probability 0.920) with cleavage site probability 0.337 between residues 24 and 25
550537005975	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
550537005976	HMMPfam hit to PF03245, Bacteriophage lysis protein, score 4e-88
550537005977	HMMPfam hit to PF07278, Protein of unknown function DUF1441, score 3e-52; This CDS is missing the majority of the very C-terminus
550537005978	This CDS is gene fragment missing most of the very N-terminus
550537005979	HMMPfam hit to PF06316, Virulence-related outer membrane protein, score 3e-05
550537005980	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
550537005981	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
550537005982	E-class dimer interface [polypeptide binding]; other site
550537005983	P-class dimer interface [polypeptide binding]; other site
550537005984	active site
550537005985	Cu2+ binding site [ion binding]; other site
550537005986	Zn2+ binding site [ion binding]; other site
550537005987	HMMPfam hit to PF00080, Superoxide dismutase, copper/zinc binding, score 6.3e-37
550537005988	PS00332 Copper/Zinc superoxide dismutase signature 2.
550537005989	Phage-related protein [Function unknown]; Region: gp18; COG4672
550537005990	HMMPfam hit to PF05100, Phage minor tail protein L, score 9.4e-145
550537005991	CDS seems to have suffered a deletion removing the C-terminus
550537005992	CDS seems to have suffered a deletion in the N terminus and a frameshift mutation following codon 789
550537005993	HMMPfam hit to PF00041, Fibronectin, type III, score 0.0058
550537005994	HMMPfam hit to PF09327, Protein of unknown function DUF1983, score 9.3e-31
550537005995	PS00017 ATP/GTP-binding site motif A (P-loop).
550537005996	CDS seems to have suffered a deletion in the N terminus
550537005997	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 1e-30
550537005998	type III secretion protein SopE; Provisional; Region: PRK15279
550537005999	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
550537006000	SopE GEF domain; Region: SopE_GEF; pfam07487
550537006001	HMMPfam hit to PF07487, Salmonella type III secretion SopE effector protein, score 2.7e-123
550537006002	HMMPfam hit to PF05364, Salmonella type III secretion SopE effector protein, score 9.5e-54
550537006004	HMMPfam hit to PF00239, Resolvase, N-terminal, score 1.6e-07
550537006005	SE12A degenerate lambdoid prophage
550537006006	Note this CDS lacks an appropriate N-terminus and has suffered a frameshift mutation following codon 196
550537006007	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 0.00012
550537006008	CDS matches central region in E. coli RecE
550537006009	The 5' end of this CDS has been deleted and there is a premature stop codon in the sequence
550537006010	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
550537006011	1 probable transmembrane helix predicted for SEN1162 by TMHMM2.0 at aa 10-32
550537006012	1 probable transmembrane helix predicted for SEN1163 by TMHMM2.0 at aa 4-21
550537006013	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
550537006014	HMMPfam hit to PF07278, Protein of unknown function DUF1441, score 2.1e-117
550537006015	This CDS has been subject to multiple deletion events
550537006016	HMMPfam hit to PF05876, Phage terminase GpA, score 1.1e-86
550537006017	This CDS has been subject to multiple deletion events
550537006018	HMMPfam hit to PF01661, Appr-1-p processing, score 6.1e-12
550537006019	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 1e-60
550537006020	HMMPfam hit to PF07484, Phage Tail Collar, score 3.4e-15
550537006021	This CDS has been subject to multiple deletion events
550537006022	HMMPfam hit to PF01661, Appr-1-p processing, score 6.1e-12
550537006023	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 1e-60
550537006024	HMMPfam hit to PF07484, Phage Tail Collar, score 3.4e-15
550537006025	1 probable transmembrane helix predicted for SEN1170 by TMHMM2.0 at aa 7-26
550537006029	HMMPfam hit to PF02796, Resolvase, helix-turn-helix region, score 1.3e-11
550537006030	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
550537006031	5 probable transmembrane helices predicted for SEN1172 by TMHMM2.0 at aa 12-34, 49-71, 76-98, 113-135 and 148-170
550537006032	1 probable transmembrane helix predicted for SEN1173 by TMHMM2.0 at aa 12-34
550537006033	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
550537006034	EamA-like transporter family; Region: EamA; pfam00892
550537006035	EamA-like transporter family; Region: EamA; pfam00892
550537006036	10 probable transmembrane helices predicted for SEN1174 by TMHMM2.0 at aa 5-27, 37-54, 67-89, 93-115, 122-139, 149-167, 179-201, 211-233, 245-267 and 271-293
550537006037	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2.8e-24
550537006038	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 1.3e-31
550537006039	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
550537006040	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
550537006041	MULE transposase domain; Region: MULE; pfam10551
550537006042	HMMPfam hit to PF00872, Transposase, mutator type, score 1.6e-107
550537006043	PS01007 Transposases, Mutator family, signature.
550537006044	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537006045	Coenzyme A binding pocket [chemical binding]; other site
550537006046	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 4.1e-11
550537006047	1 probable transmembrane helix predicted for SEN1180 by TMHMM2.0 at aa 30-52
550537006048	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
550537006049	HMMPfam hit to PF07166, Protein of unknown function DUF1398, score 3.5e-91
550537006050	1 probable transmembrane helix predicted for SEN1181 by TMHMM2.0 at aa 32-54
550537006051	type III secretion protein SopE2; Provisional; Region: PRK15280
550537006052	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
550537006053	SopE GEF domain; Region: SopE_GEF; pfam07487
550537006054	HMMPfam hit to PF05364, Salmonella type III secretion SopE effector protein, score 6.6e-61
550537006055	HMMPfam hit to PF07487, Salmonella type III secretion SopE effector protein, score 6.1e-136
550537006056	1 probable transmembrane helix predicted for SEN1183 by TMHMM2.0 at aa 7-29
550537006057	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
550537006058	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
550537006059	HMMPfam hit to PF00149, Metallophosphoesterase, score 2.7e-16
550537006060	PS00125 Serine/threonine specific protein phosphatases signature.
550537006061	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
550537006062	HMMPfam hit to PF07358, Protein of unknown function DUF1482, score 1.7e-39
550537006063	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
550537006064	HMMPfam hit to PF07351, Protein of unknown function DUF1480, score 2e-65
550537006065	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
550537006066	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
550537006067	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
550537006068	HMMPfam hit to PF01189, Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, score 1.1e-79
550537006069	PS01153 NOL1/NOP2/sun family signature.
550537006070	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
550537006071	mce related protein; Region: MCE; pfam02470
550537006072	mce related protein; Region: MCE; pfam02470
550537006073	mce related protein; Region: MCE; pfam02470
550537006074	mce related protein; Region: MCE; pfam02470
550537006075	mce related protein; Region: MCE; pfam02470
550537006076	mce related protein; Region: MCE; pfam02470
550537006077	HMMPfam hit to PF02470, Mammalian cell entry related, score 7.1e-19
550537006078	HMMPfam hit to PF02470, Mammalian cell entry related, score 5.3e-21
550537006079	HMMPfam hit to PF02470, Mammalian cell entry related, score 0.00066
550537006080	HMMPfam hit to PF02470, Mammalian cell entry related, score 7.2e-08
550537006081	HMMPfam hit to PF02470, Mammalian cell entry related, score 4.8e-13
550537006082	HMMPfam hit to PF02470, Mammalian cell entry related, score 0.0001
550537006083	HMMPfam hit to PF02470, Mammalian cell entry related, score 1.4e-29
550537006084	1 probable transmembrane helix predicted for SEN1188 by TMHMM2.0 at aa 22-41
550537006085	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
550537006086	Paraquat-inducible protein A; Region: PqiA; pfam04403
550537006087	Paraquat-inducible protein A; Region: PqiA; pfam04403
550537006088	HMMPfam hit to PF04403, Paraquat-inducible protein A, score 3.3e-98
550537006089	8 probable transmembrane helices predicted for SEN1189 by TMHMM2.0 at aa 65-84, 119-141, 162-184, 188-210, 268-290, 310-339, 351-373 and 383-405
550537006090	HMMPfam hit to PF04403, Paraquat-inducible protein A, score 2e-92
550537006091	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
550537006092	GAF domain; Region: GAF_2; pfam13185
550537006093	HMMPfam hit to PF01590, GAF, score 1.8e-08
550537006094	ProP expression regulator; Provisional; Region: PRK04950
550537006095	ProQ/FINO family; Region: ProQ; pfam04352
550537006096	HMMPfam hit to PF04352, ProQ activator of osmoprotectant transporter ProP, score 5.8e-102
550537006097	carboxy-terminal protease; Provisional; Region: PRK11186
550537006098	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
550537006099	protein binding site [polypeptide binding]; other site
550537006100	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
550537006101	Catalytic dyad [active]
550537006102	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
550537006103	HMMPfam hit to PF00595, PDZ/DHR/GLGF, score 2.7e-17
550537006104	HMMPfam hit to PF03572, Peptidase S41, score 1.9e-66
550537006105	heat shock protein HtpX; Provisional; Region: PRK05457
550537006106	HMMPfam hit to PF06509, Peptidase M48B, HtpX peptidase N-terminal, score 4.5e-55
550537006107	4 probable transmembrane helices predicted for SEN1193 by TMHMM2.0 at aa 5-27, 32-54, 158-180 and 195-217
550537006108	HMMPfam hit to PF01435, Peptidase M48, Ste24p, score 5.2e-47
550537006109	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006110	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537006111	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537006112	putative substrate translocation pore; other site
550537006113	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537006114	12 probable transmembrane helices predicted for SEN1194 by TMHMM2.0 at aa 21-43, 53-75, 87-109, 113-132, 144-166, 171-193, 205-227, 231-249, 269-291, 306-328, 335-357 and 426-448
550537006115	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 8.5e-58
550537006116	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
550537006117	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537006118	dimerization interface [polypeptide binding]; other site
550537006119	putative Zn2+ binding site [ion binding]; other site
550537006120	putative DNA binding site [nucleotide binding]; other site
550537006121	Bacterial transcriptional regulator; Region: IclR; pfam01614
550537006122	HMMPfam hit to PF09339, Transcriptional regulator IclR, N-terminal, score 3e-29
550537006123	HMMPfam hit to PF01614, Transcriptional regulator IclR, C-terminal, score 4.4e-65
550537006124	PS01051 Bacterial regulatory proteins, iclR family signature.
550537006125	YobH-like protein; Region: YobH; pfam13996
550537006126	1 probable transmembrane helix predicted for SEN1196 by TMHMM2.0 at aa 7-29
550537006127	PhoPQ regulatory protein; Provisional; Region: PRK10299
550537006128	1 probable transmembrane helix predicted for SEN1197 by TMHMM2.0 at aa 7-26
550537006129	YebO-like protein; Region: YebO; pfam13974
550537006130	1 probable transmembrane helix predicted for SEN1198 by TMHMM2.0 at aa 10-32
550537006131	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
550537006132	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
550537006133	DNA-binding site [nucleotide binding]; DNA binding site
550537006134	RNA-binding motif; other site
550537006135	HMMPfam hit to PF00313, Cold-shock protein, DNA-binding, score 3.2e-43
550537006136	PS00352 'Cold-shock' DNA-binding domain signature.
550537006137	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
550537006138	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
550537006139	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
550537006140	1 probable transmembrane helix predicted for SEN1201 by TMHMM2.0 at aa 16-38
550537006141	HMMPfam hit to PF03717, Penicillin-binding protein, dimerisation domain, score 3.9e-54
550537006142	HMMPfam hit to PF00905, Penicillin-binding protein, transpeptidase, score 4.8e-107
550537006143	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
550537006144	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537006145	S-adenosylmethionine binding site [chemical binding]; other site
550537006146	HMMPfam hit to PF08241, Methyltransferase type 11, score 8.5e-18
550537006147	hypothetical protein; Provisional; Region: PRK11469
550537006148	Domain of unknown function DUF; Region: DUF204; pfam02659
550537006149	Domain of unknown function DUF; Region: DUF204; pfam02659
550537006150	6 probable transmembrane helices predicted for SEN1203 by TMHMM2.0 at aa 18-40, 57-79, 89-111, 124-146, 151-173 and 186-205
550537006151	HMMPfam hit to PF02659, Protein of unknown function DUF204, score 1.8e-33
550537006152	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006153	HMMPfam hit to PF02659, Protein of unknown function DUF204, score 5e-39
550537006154	hypothetical protein; Provisional; Region: PRK02913
550537006155	HMMPfam hit to PF06173, Protein of unknown function DUF986, score 1e-100
550537006156	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
550537006157	HMMPfam hit to PF03613, Phosphotransferase system, mannose/fructose/sorbose family IID component, score 5.7e-186
550537006158	5 probable transmembrane helices predicted for SEN1205 by TMHMM2.0 at aa 105-127, 142-164, 185-207, 236-258 and 265-284
550537006159	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006160	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
550537006161	HMMPfam hit to PF03609, Phosphotransferase system, sorbose-specific IIC subunit, score 4.7e-149
550537006162	7 probable transmembrane helices predicted for SEN1206 by TMHMM2.0 at aa 5-27, 34-56, 66-88, 95-117, 143-165, 178-200 and 215-237
550537006163	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006164	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
550537006165	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
550537006166	active pocket/dimerization site; other site
550537006167	active site
550537006168	phosphorylation site [posttranslational modification]
550537006169	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
550537006170	active site
550537006171	phosphorylation site [posttranslational modification]
550537006172	HMMPfam hit to PF03830, Phosphotransferase system, sorbose subfamily IIB component, score 5.2e-97
550537006173	HMMPfam hit to PF03610, Phosphotransferase system, fructose subfamily IIA component, score 2.4e-52
550537006174	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
550537006175	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
550537006176	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
550537006177	Transporter associated domain; Region: CorC_HlyC; smart01091
550537006178	HMMPfam hit to PF03741, Integral membrane protein TerC, score 1.3e-36
550537006179	7 probable transmembrane helices predicted for SEN1209 by TMHMM2.0 at aa 13-35, 48-70, 85-102, 123-145, 150-172, 185-207 and 212-231
550537006180	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 5.9e-22
550537006181	HMMPfam hit to PF03471, Transporter-associated region, score 1e-18
550537006182	phage resistance protein; Provisional; Region: PRK10551
550537006183	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
550537006184	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537006185	HMMPfam hit to PF00563, EAL, score 1.9e-110
550537006186	1 probable transmembrane helix predicted for SEN1210 by TMHMM2.0 at aa 13-35
550537006187	L-serine deaminase; Provisional; Region: PRK15023
550537006188	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
550537006189	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
550537006190	HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 1.3e-205
550537006191	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006192	HMMPfam hit to PF03315, Serine dehydratase beta chain, score 1.6e-105
550537006193	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
550537006194	putative active site [active]
550537006195	putative CoA binding site [chemical binding]; other site
550537006196	nudix motif; other site
550537006197	metal binding site [ion binding]; metal-binding site
550537006198	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 5.1e-20
550537006199	PS01293 Uncharacterized protein family UPF0035 signature.
550537006200	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
550537006201	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
550537006202	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
550537006203	HMMPfam hit to PF00425, Chorismate binding, C-terminal, score 8.5e-142
550537006204	HMMPfam hit to PF04715, Anthranilate synthase component I, N-terminal, score 1.1e-34
550537006205	hypothetical protein; Provisional; Region: PRK05114
550537006206	HMMPfam hit to PF03701, Protein of unknown function UPF0181, score 7.9e-31
550537006207	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
550537006208	homotrimer interaction site [polypeptide binding]; other site
550537006209	putative active site [active]
550537006210	HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 1.1e-35
550537006211	PS01094 Uncharacterized protein family UPF0076 signature.
550537006212	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
550537006213	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
550537006214	DEAD_2; Region: DEAD_2; pfam06733
550537006215	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
550537006216	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006217	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
550537006218	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006219	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
550537006220	Glycoprotease family; Region: Peptidase_M22; pfam00814
550537006221	HMMPfam hit to PF00814, Peptidase M22, glycoprotease, score 5.7e-57
550537006222	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
550537006223	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006224	HMMPfam hit to PF03843, Outer membrane lipoprotein Slp, score 1e-94
550537006225	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
550537006226	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
550537006227	acyl-activating enzyme (AAE) consensus motif; other site
550537006228	putative AMP binding site [chemical binding]; other site
550537006229	putative active site [active]
550537006230	putative CoA binding site [chemical binding]; other site
550537006231	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 2.4e-136
550537006232	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537006233	PS00455  AMP-binding domain signature.
550537006234	ribonuclease D; Provisional; Region: PRK10829
550537006235	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
550537006236	catalytic site [active]
550537006237	putative active site [active]
550537006238	putative substrate binding site [chemical binding]; other site
550537006239	HRDC domain; Region: HRDC; cl02578
550537006240	HMMPfam hit to PF01612, 3'-5' exonuclease, score 7.6e-70
550537006241	HMMPfam hit to PF00570, Helicase and RNase D C-terminal, HRDC, score 3.2e-23
550537006242	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
550537006243	HMMPfam hit to PF03776, Septum formation topological specificity factor MinE, score 2.5e-54
550537006244	cell division inhibitor MinD; Provisional; Region: PRK10818
550537006245	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
550537006246	Switch I; other site
550537006247	Switch II; other site
550537006248	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase, score 3.1e-27
550537006249	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006250	septum formation inhibitor; Reviewed; Region: minC; PRK03511
550537006251	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
550537006252	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
550537006253	HMMPfam hit to PF03775, Septum formation inhibitor MinC, C-terminal, score 5.8e-62
550537006254	HMMPfam hit to PF05209, Septum formation inhibitor MinC, N-terminal, score 1.3e-48
550537006255	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
550537006256	HMMPfam hit to PF05166, Protein of unknown function DUF709, score 2.7e-58
550537006257	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
550537006258	hypothetical protein; Provisional; Region: PRK10691
550537006259	HMMPfam hit to PF01557, Fumarylacetoacetase, C-terminal-like, score 6.2e-85
550537006260	hypothetical protein; Provisional; Region: PRK05170
550537006261	HMMPfam hit to PF03692, Protein of unknown function UPF0153, score 4.1e-23
550537006262	GnsA/GnsB family; Region: GnsAB; pfam08178
550537006263	HMMPfam hit to PF08178, GnsAGnsB, score 7.3e-31
550537006264	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
550537006265	HMMPfam hit to PF09313, Protein of unknown function DUF1971, score 1.8e-45
550537006266	disulfide bond formation protein B; Provisional; Region: PRK01749
550537006267	4 probable transmembrane helices predicted for SEN1230 by TMHMM2.0 at aa 13-32, 42-64, 71-93 and 144-166
550537006268	HMMPfam hit to PF02600, Disulphide bond formation protein DsbB, score 1.1e-74
550537006269	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
550537006270	transmembrane helices; other site
550537006271	HMMPfam hit to PF06450, Na+/H+ antiporter NhaB, score 0
550537006272	12 probable transmembrane helices predicted for SEN1231 by TMHMM2.0 at aa 26-48, 61-83, 93-115, 128-145, 150-169, 197-219, 239-261, 299-331, 346-368, 389-411, 453-472 and 479-501
550537006273	fatty acid metabolism regulator; Provisional; Region: PRK04984
550537006274	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537006275	DNA-binding site [nucleotide binding]; DNA binding site
550537006276	FadR C-terminal domain; Region: FadR_C; pfam07840
550537006277	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 7.4e-26
550537006278	PS00043 Bacterial regulatory proteins, gntR family signature.
550537006279	HMMPfam hit to PF07840, Fatty acid responsive transcription factor FadR, C-terminal, score 4e-120
550537006280	SpoVR family protein; Provisional; Region: PRK11767
550537006281	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
550537006282	HMMPfam hit to PF04293, Sporulation stage V, protein R, score 0
550537006283	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
550537006284	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
550537006285	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.8e-112
550537006286	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006287	alanine racemase; Reviewed; Region: dadX; PRK03646
550537006288	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
550537006289	active site
550537006290	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537006291	substrate binding site [chemical binding]; other site
550537006292	catalytic residues [active]
550537006293	dimer interface [polypeptide binding]; other site
550537006294	HMMPfam hit to PF01168, Alanine racemase, N-terminal, score 1.5e-83
550537006295	PS00395 Alanine racemase pyridoxal-phosphate attachment site.
550537006296	HMMPfam hit to PF00842, Alanine racemase, C-terminal, score 4.5e-62
550537006297	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
550537006298	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
550537006299	TrkA-C domain; Region: TrkA_C; pfam02080
550537006300	Transporter associated domain; Region: CorC_HlyC; smart01091
550537006301	HMMPfam hit to PF03471, Transporter-associated region, score 1.4e-23
550537006302	HMMPfam hit to PF02080, TrkA-C, score 2.5e-11
550537006303	HMMPfam hit to PF00999, Sodium/hydrogen exchanger, score 6.2e-73
550537006304	11 probable transmembrane helices predicted for SEN1236 by TMHMM2.0 at aa 4-26, 31-53, 57-74, 87-109, 119-141, 187-209, 232-254, 267-289, 299-321, 334-356 and 361-383
550537006305	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
550537006306	dimer interface [polypeptide binding]; other site
550537006307	catalytic triad [active]
550537006308	HMMPfam hit to PF02016, Peptidase S66, LD-carboxypeptidase A, score 1e-57
550537006309	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
550537006310	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
550537006311	N-acetyl-D-glucosamine binding site [chemical binding]; other site
550537006312	catalytic residue [active]
550537006313	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006314	HMMPfam hit to PF01464, Lytic transglycosylase-like, catalytic, score 1.4e-38
550537006315	PS00922 Prokaryotic transglycosylases signature.
550537006316	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
550537006317	Flagellar regulator YcgR; Region: YcgR; pfam07317
550537006318	PilZ domain; Region: PilZ; pfam07238
550537006319	HMMPfam hit to PF07238, Type IV pilus assembly PilZ, score 6.1e-11
550537006320	HMMPfam hit to PF07317, YcgR, score 6e-63
550537006321	hypothetical protein; Provisional; Region: PRK10457
550537006322	3 probable transmembrane helices predicted for SEN1240 by TMHMM2.0 at aa 4-22, 27-49 and 59-81
550537006323	HMMPfam hit to PF04226, Transglycosylase-associated protein, score 5.7e-20
550537006324	trehalase; Provisional; Region: treA; PRK13271
550537006325	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
550537006326	HMMPfam hit to PF01204, Glycoside hydrolase, family 37, score 5.3e-259
550537006327	PS00928 Trehalase signature 2.
550537006328	PS00927 Trehalase signature 1.
550537006329	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
550537006330	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
550537006331	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
550537006332	NAD(P) binding site [chemical binding]; other site
550537006333	HMMPfam hit to PF00208, Glu/Leu/Phe/Val dehydrogenase, C-terminal, score 7.3e-110
550537006334	PS00137 Serine proteases, subtilase family, histidine active site.
550537006335	HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimerisation region, score 2.2e-66
550537006336	PS00074 Glu / Leu / Phe / Val dehydrogenases active site.
550537006337	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
550537006338	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
550537006339	HMMPfam hit to PF02322, Cytochrome bd ubiquinol oxidase, subunit II, score 7e-191
550537006340	8 probable transmembrane helices predicted for SEN1244 by TMHMM2.0 at aa 7-24, 80-102, 123-145, 165-187, 208-230, 258-280, 292-314 and 334-356
550537006341	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006342	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006343	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
550537006344	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
550537006345	HMMPfam hit to PF01654, Cytochrome bd ubiquinol oxidase, subunit I, score 0
550537006346	9 probable transmembrane helices predicted for SEN1245 by TMHMM2.0 at aa 20-42, 54-76, 96-118, 125-147, 186-208, 215-237, 387-409, 421-443 and 471-493
550537006347	Hydrogenase 1 operon HyaABCDEF
550537006348	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
550537006349	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
550537006350	HMMPfam hit to PF04809, HupH hydrogenase expression protein, C-terminal conserved region, score 6.6e-61
550537006351	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
550537006352	HMMPfam hit to PF07449, Hydrogenase-1 expression HyaE, score 5.1e-63
550537006353	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
550537006354	putative substrate-binding site; other site
550537006355	nickel binding site [ion binding]; other site
550537006356	HMMPfam hit to PF01750, Peptidase A31, hydrogen uptake protein, score 2.6e-51
550537006357	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
550537006358	HMMPfam hit to PF01292, Cytochrome B561, bacterial, score 1e-78
550537006359	4 probable transmembrane helices predicted for SEN1249 by TMHMM2.0 at aa 28-47, 67-89, 141-160 and 194-211
550537006360	PS00883 Nickel-dependent hydrogenases b-type cytochrome subunit signature 2.
550537006361	hydrogenase 1 large subunit; Provisional; Region: PRK10170
550537006362	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
550537006363	HMMPfam hit to PF00374, Nickel-dependent hydrogenase, large subunit, score 0
550537006364	PS00508 Nickel-dependent hydrogenases large subunit signature 2.
550537006365	PS00507 Nickel-dependent hydrogenases large subunit signature 1.
550537006366	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
550537006367	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
550537006368	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
550537006369	2 probable transmembrane helices predicted for SEN1251 by TMHMM2.0 at aa 20-39 and 326-348
550537006370	HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 kDa subunit, score 3.8e-17
550537006371	HMMPfam hit to PF08425, NiFe dehydrogenase small subunit, N-terminal, score 2.4e-46
550537006372	2 probable transmembrane helices predicted for SEN1253 by TMHMM2.0 at aa 12-34 and 44-61
550537006373	PS00881 Protein splicing signature.
550537006374	3 probable transmembrane helices predicted for SEN1254 by TMHMM2.0 at aa 26-45, 91-108 and 113-135
550537006375	GTP-binding protein YchF; Reviewed; Region: PRK09601
550537006376	YchF GTPase; Region: YchF; cd01900
550537006377	G1 box; other site
550537006378	GTP/Mg2+ binding site [chemical binding]; other site
550537006379	Switch I region; other site
550537006380	G2 box; other site
550537006381	Switch II region; other site
550537006382	G3 box; other site
550537006383	G4 box; other site
550537006384	G5 box; other site
550537006385	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
550537006386	HMMPfam hit to PF06071, Protein of unknown function DUF933, score 3.4e-60
550537006387	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 1.4e-31
550537006388	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006389	PS00443 Glutamine amidotransferases class-II active site.
550537006390	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
550537006391	putative active site [active]
550537006392	catalytic residue [active]
550537006393	HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase, score 7.9e-111
550537006394	PS00217 Sugar transport proteins signature 2.
550537006395	PS01196 Peptidyl-tRNA hydrolase signature 2.
550537006396	hypothetical protein; Provisional; Region: PRK10692
550537006397	2 probable transmembrane helices predicted for SEN1257 by TMHMM2.0 at aa 7-29 and 39-61
550537006398	putative transporter; Provisional; Region: PRK11660
550537006399	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
550537006400	Sulfate transporter family; Region: Sulfate_transp; pfam00916
550537006401	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
550537006402	HMMPfam hit to PF01740, Sulphate transporter/antisigma-factor antagonist STAS, score 7.3e-23
550537006403	HMMPfam hit to PF00916, Sulphate transporter, score 5.3e-105
550537006404	11 probable transmembrane helices predicted for SEN1258 by TMHMM2.0 at aa 25-47, 54-76, 91-113, 122-144, 169-191, 204-226, 269-291, 311-333, 338-360, 362-380 and 400-431
550537006405	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006406	PS01130 Sulfate transporters signature.
550537006407	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
550537006408	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
550537006409	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537006410	active site
550537006411	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 2.1e-37
550537006412	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
550537006413	PS00114 Phosphoribosyl pyrophosphate synthetase signature.
550537006414	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537006415	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
550537006416	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
550537006417	HMMPfam hit to PF08544, GHMP kinase, C-terminal, score 9.4e-08
550537006418	HMMPfam hit to PF00288, GHMP kinase, score 8.1e-19
550537006419	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
550537006420	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
550537006421	HMMPfam hit to PF03550, Outer membrane lipoprotein LolB, score 2.5e-84
550537006422	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006423	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006424	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
550537006425	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
550537006426	tRNA; other site
550537006427	putative tRNA binding site [nucleotide binding]; other site
550537006428	putative NADP binding site [chemical binding]; other site
550537006429	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
550537006430	HMMPfam hit to PF05201, Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal, score 2.3e-86
550537006431	PS00747 Glutamyl-tRNA reductase signature.
550537006432	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006433	HMMPfam hit to PF01488, Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase, score 3.4e-69
550537006434	HMMPfam hit to PF00745, Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, C-terminal, score 2.5e-37
550537006435	peptide chain release factor 1; Validated; Region: prfA; PRK00591
550537006436	This domain is found in peptide chain release factors; Region: PCRF; smart00937
550537006437	RF-1 domain; Region: RF-1; pfam00472
550537006438	HMMPfam hit to PF03462, PCRF, score 9.6e-75
550537006439	HMMPfam hit to PF00472, Class I peptide chain release factor, score 3.2e-74
550537006440	PS00745 Prokaryotic-type class I peptide chain release factors signature.
550537006441	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
550537006442	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537006443	HMMPfam hit to PF08241, Methyltransferase type 11, score 0.00039
550537006444	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006445	PS00092 N-6 Adenine-specific DNA methylases signature.
550537006446	hypothetical protein; Provisional; Region: PRK10278
550537006447	HMMPfam hit to PF04247, Invasion gene expression up-regulator, SirB, score 4.1e-58
550537006448	4 probable transmembrane helices predicted for SEN1265 by TMHMM2.0 at aa 5-27, 39-60, 70-92 and 104-123
550537006449	hypothetical protein; Provisional; Region: PRK10941
550537006450	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
550537006451	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537006452	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
550537006453	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
550537006454	HMMPfam hit to PF00793, DAHP synthetase I/KDSA, score 2.9e-116
550537006455	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
550537006456	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
550537006457	11 probable transmembrane helices predicted for SEN1268 by TMHMM2.0 at aa 13-32, 36-58, 71-93, 108-127, 139-161, 166-188, 220-237, 247-269, 290-312, 317-339 and 346-365
550537006458	HMMPfam hit to PF01699, Sodium/calcium exchanger membrane region, score 6.1e-14
550537006459	cation transport regulator; Reviewed; Region: chaB; PRK09582
550537006460	HMMPfam hit to PF06150, ChaB, score 7.2e-11
550537006461	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
550537006462	HMMPfam hit to PF02635, DsrE-like protein, score 3.4e-38
550537006463	putative invasin; Provisional; Region: PRK10177
550537006464	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
550537006465	transcriptional regulator NarL; Provisional; Region: PRK10651
550537006466	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537006467	active site
550537006468	phosphorylation site [posttranslational modification]
550537006469	intermolecular recognition site; other site
550537006470	dimerization interface [polypeptide binding]; other site
550537006471	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537006472	DNA binding residues [nucleotide binding]
550537006473	dimerization interface [polypeptide binding]; other site
550537006474	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 7.1e-27
550537006475	PS00622 Bacterial regulatory proteins, luxR family signature.
550537006476	HMMPfam hit to PF00072, Response regulator receiver, score 1.8e-42
550537006477	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
550537006478	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
550537006479	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537006480	dimerization interface [polypeptide binding]; other site
550537006481	Histidine kinase; Region: HisKA_3; pfam07730
550537006482	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537006483	ATP binding site [chemical binding]; other site
550537006484	Mg2+ binding site [ion binding]; other site
550537006485	G-X-G motif; other site
550537006486	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 4.2e-23
550537006487	HMMPfam hit to PF07730, Histidine kinase, dimerisation and phosphoacceptor region, score 8.9e-20
550537006488	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 2.2e-12
550537006489	2 probable transmembrane helices predicted for SEN1273 by TMHMM2.0 at aa 15-37 and 154-176
550537006490	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
550537006491	12 probable transmembrane helices predicted for SEN1274 by TMHMM2.0 at aa 38-60, 75-97, 104-123, 133-155, 176-198, 213-235, 256-278, 288-310, 322-344, 348-370, 404-421 and 436-458
550537006492	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.1e-15
550537006493	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
550537006494	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
550537006495	[4Fe-4S] binding site [ion binding]; other site
550537006496	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537006497	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537006498	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537006499	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
550537006500	molybdopterin cofactor binding site; other site
550537006501	PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
550537006502	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 7.4e-178
550537006503	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006504	PS00490 Prokaryotic molybdopterin oxidoreductases signature 2.
550537006505	PS00037 Myb DNA-binding domain repeat signature 1.
550537006506	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 6.5e-25
550537006507	PS00932 Prokaryotic molybdopterin oxidoreductases signature 3.
550537006508	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
550537006509	4Fe-4S binding domain; Region: Fer4; cl02805
550537006510	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.011
550537006511	PS00190 Cytochrome c family heme-binding site signature.
550537006512	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
550537006513	HMMPfam hit to PF02613, Nitrate reductase, delta subunit, score 6.1e-88
550537006514	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
550537006515	HMMPfam hit to PF02665, Nitrate reductase, gamma subunit, score 8.5e-120
550537006516	5 probable transmembrane helices predicted for SEN1278 by TMHMM2.0 at aa 4-26, 47-69, 89-108, 127-149 and 184-206
550537006517	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537006518	Sel1-like repeats; Region: SEL1; smart00671
550537006519	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537006520	Sel1-like repeats; Region: SEL1; smart00671
550537006521	Sel1-like repeats; Region: SEL1; smart00671
550537006522	Sel1-like repeats; Region: SEL1; smart00671
550537006523	Sel1-like repeats; Region: SEL1; smart00671
550537006524	Sel1-like repeats; Region: SEL1; smart00671
550537006525	Sel1-like repeats; Region: SEL1; smart00671
550537006526	Sel1-like repeats; Region: SEL1; smart00671
550537006527	Sel1-like repeats; Region: SEL1; smart00671
550537006528	HMMPfam hit to PF08238, Sel1-like, score 1.4e-09
550537006529	HMMPfam hit to PF08238, Sel1-like, score 1.9e-06
550537006530	HMMPfam hit to PF08238, Sel1-like, score 0.00019
550537006531	HMMPfam hit to PF08238, Sel1-like, score 4.4e-07
550537006532	HMMPfam hit to PF08238, Sel1-like, score 3e-05
550537006533	HMMPfam hit to PF08238, Sel1-like, score 8.6e-07
550537006534	HMMPfam hit to PF08238, Sel1-like, score 1e-10
550537006535	HMMPfam hit to PF08238, Sel1-like, score 8.2e-09
550537006536	HMMPfam hit to PF08238, Sel1-like, score 4.3e-11
550537006537	HMMPfam hit to PF08238, Sel1-like, score 0.00019
550537006538	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
550537006539	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
550537006540	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
550537006541	putative active site [active]
550537006542	putative substrate binding site [chemical binding]; other site
550537006543	putative cosubstrate binding site; other site
550537006544	catalytic site [active]
550537006545	HMMPfam hit to PF00551, Formyl transferase, N-terminal, score 1e-77
550537006546	HMMPfam hit to PF01842, Amino acid-binding ACT, score 2.2e-06
550537006547	SEC-C motif; Region: SEC-C; pfam02810
550537006548	hypothetical protein; Provisional; Region: PRK04233
550537006549	HMMPfam hit to PF02810, SEC-C motif, score 3.8e-06
550537006550	HMMPfam hit to PF02810, SEC-C motif, score 2.3e-07
550537006551	hypothetical protein; Provisional; Region: PRK10279
550537006552	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
550537006553	active site
550537006554	nucleophile elbow; other site
550537006555	HMMPfam hit to PF01734, Patatin, score 5.5e-54
550537006556	PS01237 Uncharacterized protein family UPF0028 signature.
550537006557	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006558	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537006559	active site
550537006560	response regulator of RpoS; Provisional; Region: PRK10693
550537006561	phosphorylation site [posttranslational modification]
550537006562	intermolecular recognition site; other site
550537006563	dimerization interface [polypeptide binding]; other site
550537006564	HMMPfam hit to PF00072, Response regulator receiver, score 9.7e-43
550537006565	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
550537006566	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
550537006567	active site
550537006568	tetramer interface; other site
550537006569	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.6e-12
550537006570	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006571	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
550537006572	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
550537006573	HMMPfam hit to PF00816, Histone-like nucleoid-structuring protein H-NS, score 1.2e-48
550537006574	thymidine kinase; Provisional; Region: PRK04296
550537006575	HMMPfam hit to PF00265, Thymidine kinase, score 6.9e-103
550537006576	PS00603 Thymidine kinase cellular-type signature.
550537006577	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
550537006578	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
550537006579	putative catalytic cysteine [active]
550537006580	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
550537006581	putative active site [active]
550537006582	metal binding site [ion binding]; metal-binding site
550537006583	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 4.7e-239
550537006584	PS00060 Iron-containing alcohol dehydrogenases signature 2.
550537006585	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537006586	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 4.2e-08
550537006587	hypothetical protein; Provisional; Region: PRK11111
550537006588	HMMPfam hit to PF01914, Multiple antibiotic resistance (MarC)-related proteins, score 1.6e-106
550537006589	6 probable transmembrane helices predicted for SEN1288 by TMHMM2.0 at aa 10-32, 52-74, 78-100, 120-142, 146-168 and 189-211
550537006590	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
550537006591	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
550537006592	peptide binding site [polypeptide binding]; other site
550537006593	1 probable transmembrane helix predicted for SEN1289 by TMHMM2.0 at aa 9-31
550537006594	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 1.3e-86
550537006595	PS01040 Bacterial extracellular solute-binding proteins, family 5 signature.
550537006596	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
550537006597	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537006598	dimer interface [polypeptide binding]; other site
550537006599	conserved gate region; other site
550537006600	putative PBP binding loops; other site
550537006601	ABC-ATPase subunit interface; other site
550537006602	6 probable transmembrane helices predicted for SEN1290 by TMHMM2.0 at aa 13-30, 102-121, 134-156, 166-188, 228-250 and 278-300
550537006603	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.3e-56
550537006604	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537006605	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
550537006606	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
550537006607	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537006608	dimer interface [polypeptide binding]; other site
550537006609	conserved gate region; other site
550537006610	ABC-ATPase subunit interface; other site
550537006611	6 probable transmembrane helices predicted for SEN1291 by TMHMM2.0 at aa 40-62, 103-125, 138-160, 164-183, 214-236 and 268-290
550537006612	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 3.6e-40
550537006613	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537006614	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
550537006615	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537006616	Walker A/P-loop; other site
550537006617	ATP binding site [chemical binding]; other site
550537006618	Q-loop/lid; other site
550537006619	ABC transporter signature motif; other site
550537006620	Walker B; other site
550537006621	D-loop; other site
550537006622	H-loop/switch region; other site
550537006623	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
550537006624	HMMPfam hit to PF00005, ABC transporter related, score 9.2e-66
550537006625	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006626	PS00211 ABC transporters family signature.
550537006627	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 7e-31
550537006628	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
550537006629	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537006630	Walker A/P-loop; other site
550537006631	ATP binding site [chemical binding]; other site
550537006632	Q-loop/lid; other site
550537006633	ABC transporter signature motif; other site
550537006634	Walker B; other site
550537006635	D-loop; other site
550537006636	H-loop/switch region; other site
550537006637	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
550537006638	HMMPfam hit to PF00005, ABC transporter related, score 1.8e-63
550537006639	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006640	PS00211 ABC transporters family signature.
550537006641	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 2.4e-35
550537006642	Ion transport protein; Region: Ion_trans; pfam00520
550537006643	Ion channel; Region: Ion_trans_2; pfam07885
550537006644	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
550537006645	Double zinc ribbon; Region: DZR; pfam12773
550537006646	6 probable transmembrane helices predicted for SEN1294 by TMHMM2.0 at aa 12-34, 44-66, 73-95, 139-161, 166-188 and 198-220
550537006647	HMMPfam hit to PF00520, Ion transport, score 1.1e-29
550537006648	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
550537006649	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
550537006650	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
550537006651	putative active site [active]
550537006652	catalytic site [active]
550537006653	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
550537006654	putative active site [active]
550537006655	catalytic site [active]
550537006656	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 6.4e-08
550537006657	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006658	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 8.1e-08
550537006659	2 probable transmembrane helices predicted for SEN1295 by TMHMM2.0 at aa 10-29 and 36-58
550537006660	YciI-like protein; Reviewed; Region: PRK11370
550537006661	HMMPfam hit to PF03795, YCII-related, score 4.3e-44
550537006662	transport protein TonB; Provisional; Region: PRK10819
550537006663	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
550537006664	HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 1.7e-17
550537006665	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
550537006666	HMMPfam hit to PF03061, Thioesterase superfamily, score 6e-21
550537006667	intracellular septation protein A; Reviewed; Region: PRK00259
550537006668	HMMPfam hit to PF04279, Intracellular septation protein A, score 1.5e-116
550537006669	5 probable transmembrane helices predicted for SEN1299 by TMHMM2.0 at aa 20-42, 51-68, 78-95, 119-141 and 151-170
550537006670	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006671	hypothetical protein; Provisional; Region: PRK02868
550537006672	HMMPfam hit to PF06790, Protein of unknown function UPF0259, score 2.7e-152
550537006673	6 probable transmembrane helices predicted for SEN1300 by TMHMM2.0 at aa 20-42, 89-111, 118-140, 144-166, 187-209 and 219-241
550537006674	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
550537006675	HMMPfam hit to PF03692, Protein of unknown function UPF0153, score 6.1e-26
550537006676	outer membrane protein W; Provisional; Region: PRK10959
550537006677	HMMPfam hit to PF03922, Outer membrane protein, OmpW, score 4.1e-107
550537006678	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
550537006679	dimanganese center [ion binding]; other site
550537006680	HMMPfam hit to PF05067, Catalase, manganese, score 1.9e-132
550537006681	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
550537006682	dinuclear metal binding motif [ion binding]; other site
550537006683	HMMPfam hit to PF05974, Protein of unknown function DUF892, score 5.6e-71
550537006684	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
550537006685	dimerization interface [polypeptide binding]; other site
550537006686	metal binding site [ion binding]; metal-binding site
550537006687	HMMPfam hit to PF05974, Protein of unknown function DUF892, score 3.3e-87
550537006688	General stress protein [General function prediction only]; Region: GsiB; COG3729
550537006689	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
550537006690	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
550537006691	substrate binding site [chemical binding]; other site
550537006692	active site
550537006693	catalytic residues [active]
550537006694	heterodimer interface [polypeptide binding]; other site
550537006695	HMMPfam hit to PF00290, Tryptophan synthase, alpha chain, score 4.5e-146
550537006696	PS00167 Tryptophan synthase alpha chain signature.
550537006697	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
550537006698	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
550537006699	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537006700	catalytic residue [active]
550537006701	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 3.2e-118
550537006702	PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site.
550537006703	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
550537006704	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
550537006705	active site
550537006706	ribulose/triose binding site [chemical binding]; other site
550537006707	phosphate binding site [ion binding]; other site
550537006708	substrate (anthranilate) binding pocket [chemical binding]; other site
550537006709	product (indole) binding pocket [chemical binding]; other site
550537006710	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
550537006711	active site
550537006712	HMMPfam hit to PF00697, N-(5'phosphoribosyl)anthranilate isomerase (PRAI), score 1.1e-93
550537006713	HMMPfam hit to PF00218, Indole-3-glycerol phosphate synthase, score 1.2e-150
550537006714	PS00614 Indole-3-glycerol phosphate synthase signature.
550537006715	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
550537006716	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
550537006717	glutamine binding [chemical binding]; other site
550537006718	catalytic triad [active]
550537006719	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
550537006720	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
550537006721	HMMPfam hit to PF00591, Glycosyl transferase, family 3, score 1.2e-153
550537006722	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006723	HMMPfam hit to PF02885, Glycosyl transferase, family 3, score 1.1e-27
550537006724	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.5e-71
550537006725	PS00442 Glutamine amidotransferases class-I active site.
550537006726	anthranilate synthase component I; Provisional; Region: PRK13564
550537006727	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
550537006728	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
550537006729	HMMPfam hit to PF00425, Chorismate binding, C-terminal, score 5e-166
550537006730	HMMPfam hit to PF04715, Anthranilate synthase component I, N-terminal, score 1.9e-30
550537006731	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
550537006732	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
550537006733	active site
550537006734	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
550537006735	HMMPfam hit to PF02811, PHP, C-terminal, score 9.8e-40
550537006736	hypothetical protein; Provisional; Region: PRK11630
550537006737	HMMPfam hit to PF01300, SUA5/yciO/yrdC, N-terminal, score 2.2e-79
550537006738	PS01147 SUA5/yciO/yrdC family signature.
550537006739	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
550537006740	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537006741	RNA binding surface [nucleotide binding]; other site
550537006742	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
550537006743	probable active site [active]
550537006744	HMMPfam hit to PF01479, RNA-binding S4, score 8.7e-09
550537006745	HMMPfam hit to PF00849, Pseudouridine synthase, score 4.2e-12
550537006746	PS01149 Rsu family of pseudouridine synthase signature.
550537006747	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
550537006748	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
550537006749	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
550537006750	homodimer interface [polypeptide binding]; other site
550537006751	Walker A motif; other site
550537006752	ATP binding site [chemical binding]; other site
550537006753	hydroxycobalamin binding site [chemical binding]; other site
550537006754	Walker B motif; other site
550537006755	HMMPfam hit to PF02572, Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR, score 4.4e-125
550537006756	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
550537006757	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
550537006758	NADP binding site [chemical binding]; other site
550537006759	homodimer interface [polypeptide binding]; other site
550537006760	active site
550537006761	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 2.2e-35
550537006762	PS00061 Short-chain dehydrogenases/reductases family signature.
550537006763	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
550537006764	putative inner membrane peptidase; Provisional; Region: PRK11778
550537006765	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
550537006766	tandem repeat interface [polypeptide binding]; other site
550537006767	oligomer interface [polypeptide binding]; other site
550537006768	active site residues [active]
550537006769	HMMPfam hit to PF08496, Peptidase S49, N-terminal proteobacteria, score 1.1e-103
550537006770	PS00043 Bacterial regulatory proteins, gntR family signature.
550537006771	2 probable transmembrane helices predicted for SEN1317 by TMHMM2.0 at aa 10-32 and 189-206
550537006772	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537006773	HMMPfam hit to PF01343, Peptidase S49, score 9e-64
550537006774	hypothetical protein; Provisional; Region: PRK11037
550537006775	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
550537006776	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
550537006777	active site
550537006778	interdomain interaction site; other site
550537006779	putative metal-binding site [ion binding]; other site
550537006780	nucleotide binding site [chemical binding]; other site
550537006781	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
550537006782	domain I; other site
550537006783	DNA binding groove [nucleotide binding]
550537006784	phosphate binding site [ion binding]; other site
550537006785	domain II; other site
550537006786	domain III; other site
550537006787	nucleotide binding site [chemical binding]; other site
550537006788	catalytic site [active]
550537006789	domain IV; other site
550537006790	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
550537006791	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
550537006792	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
550537006793	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
550537006794	HMMPfam hit to PF01751, TOPRIM, score 2.8e-39
550537006795	HMMPfam hit to PF01131, DNA topoisomerase, type IA, central, score 9.3e-202
550537006796	PS00396 Prokaryotic DNA topoisomerase I active site.
550537006797	HMMPfam hit to PF01396, DNA topoisomerase, type IA, zn finger, score 0.00056
550537006798	HMMPfam hit to PF01396, DNA topoisomerase, type IA, zn finger, score 1.1e-13
550537006799	HMMPfam hit to PF08272, DNA topoisomerase I, zinc ribbon-like, bacterial-type, score 1.8e-15
550537006800	HMMPfam hit to PF08272, DNA topoisomerase I, zinc ribbon-like, bacterial-type, score 4.5e-21
550537006801	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
550537006802	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537006803	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
550537006804	substrate binding site [chemical binding]; other site
550537006805	putative dimerization interface [polypeptide binding]; other site
550537006806	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 8.5e-15
550537006807	PS00044 Bacterial regulatory proteins, lysR family signature.
550537006808	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
550537006809	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.5e-45
550537006810	aconitate hydratase; Validated; Region: PRK09277
550537006811	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
550537006812	substrate binding site [chemical binding]; other site
550537006813	ligand binding site [chemical binding]; other site
550537006814	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
550537006815	substrate binding site [chemical binding]; other site
550537006816	HMMPfam hit to PF00330, Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, score 3.3e-280
550537006817	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006818	PS00450 Aconitase family signature 1.
550537006819	PS01244 Aconitase family signature 2.
550537006820	HMMPfam hit to PF00694, Aconitase A/isopropylmalate dehydratase small subunit, swivel, score 5.8e-66
550537006821	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
550537006822	dimerization interface [polypeptide binding]; other site
550537006823	active site
550537006824	HMMPfam hit to PF00925, GTP cyclohydrolase II, score 1.6e-116
550537006825	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
550537006826	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
550537006827	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
550537006828	active site
550537006829	6 probable transmembrane helices predicted for SEN1323 by TMHMM2.0 at aa 9-31, 51-68, 75-92, 157-179, 186-208 and 212-229
550537006830	HMMPfam hit to PF01569, Phosphatidic acid phosphatase type 2-like, score 8.5e-25
550537006831	Predicted membrane protein [Function unknown]; Region: COG3771
550537006832	HMMPfam hit to PF06305, Protein of unknown function DUF1049, score 1.9e-57
550537006833	2 probable transmembrane helices predicted for SEN1324 by TMHMM2.0 at aa 5-23 and 43-65
550537006834	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
550537006835	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
550537006836	TPR motif; other site
550537006837	binding surface
550537006838	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
550537006839	binding surface
550537006840	TPR motif; other site
550537006841	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 0.00032
550537006842	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
550537006843	active site
550537006844	dimer interface [polypeptide binding]; other site
550537006845	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase, core, score 4.2e-85
550537006846	PS00156 Orotidine 5'-phosphate decarboxylase active site.
550537006847	translation initiation factor Sui1; Validated; Region: PRK06824
550537006848	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
550537006849	putative rRNA binding site [nucleotide binding]; other site
550537006850	HMMPfam hit to PF01253, Translation initiation factor SUI1, score 7.2e-36
550537006851	PS01118 Translation initiation factor SUI1 signature.
550537006852	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537006853	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537006854	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537006855	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 2.7e-34
550537006856	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 3.7e-16
550537006857	RNase II stability modulator; Provisional; Region: PRK10060
550537006858	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537006859	putative active site [active]
550537006860	heme pocket [chemical binding]; other site
550537006861	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537006862	metal binding site [ion binding]; metal-binding site
550537006863	active site
550537006864	I-site; other site
550537006865	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537006866	HMMPfam hit to PF00563, EAL, score 7.9e-125
550537006867	HMMPfam hit to PF00990, GGDEF, score 2.5e-62
550537006868	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006869	exoribonuclease II; Provisional; Region: PRK05054
550537006870	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
550537006871	RNB domain; Region: RNB; pfam00773
550537006872	S1 RNA binding domain; Region: S1; pfam00575
550537006873	HMMPfam hit to PF00575, S1, RNA binding, score 5.4e-10
550537006874	HMMPfam hit to PF00773, Ribonuclease II and R, score 2.3e-128
550537006875	PS01175 Ribonuclease II family signature.
550537006876	HMMPfam hit to PF08206, Ribonuclease B, OB region N-terminal, score 4.8e-24
550537006877	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
550537006878	Uncharacterized conserved protein [Function unknown]; Region: COG2128
550537006879	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
550537006880	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
550537006881	NAD binding site [chemical binding]; other site
550537006882	homotetramer interface [polypeptide binding]; other site
550537006883	homodimer interface [polypeptide binding]; other site
550537006884	substrate binding site [chemical binding]; other site
550537006885	active site
550537006886	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 0.00042
550537006887	Note the frameshift mutation following codon 70
550537006888	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
550537006889	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
550537006890	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537006891	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
550537006892	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537006893	Walker A/P-loop; other site
550537006894	ATP binding site [chemical binding]; other site
550537006895	Q-loop/lid; other site
550537006896	ABC transporter signature motif; other site
550537006897	Walker B; other site
550537006898	D-loop; other site
550537006899	H-loop/switch region; other site
550537006900	HMMPfam hit to PF00005, ABC transporter related, score 1.5e-65
550537006901	PS00211 ABC transporters family signature.
550537006902	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006903	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
550537006904	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537006905	Walker A/P-loop; other site
550537006906	ATP binding site [chemical binding]; other site
550537006907	Q-loop/lid; other site
550537006908	ABC transporter signature motif; other site
550537006909	Walker B; other site
550537006910	D-loop; other site
550537006911	H-loop/switch region; other site
550537006912	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
550537006913	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 5.4e-24
550537006914	HMMPfam hit to PF00005, ABC transporter related, score 7.5e-68
550537006915	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006916	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
550537006917	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
550537006918	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537006919	dimer interface [polypeptide binding]; other site
550537006920	conserved gate region; other site
550537006921	putative PBP binding loops; other site
550537006922	ABC-ATPase subunit interface; other site
550537006923	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 9.9e-30
550537006924	6 probable transmembrane helices predicted for SEN1339 by TMHMM2.0 at aa 30-52, 99-121, 134-156, 198-217, 224-243 and 258-280
550537006925	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
550537006926	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537006927	dimer interface [polypeptide binding]; other site
550537006928	conserved gate region; other site
550537006929	putative PBP binding loops; other site
550537006930	ABC-ATPase subunit interface; other site
550537006931	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.4e-52
550537006932	4 probable transmembrane helices predicted for SEN1340 by TMHMM2.0 at aa 23-45, 57-79, 194-216 and 229-251
550537006933	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
550537006934	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
550537006935	peptide binding site [polypeptide binding]; other site
550537006936	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 9.8e-71
550537006937	PS01040 Bacterial extracellular solute-binding proteins, family 5 signature.
550537006938	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
550537006939	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537006940	Walker A motif; other site
550537006941	ATP binding site [chemical binding]; other site
550537006942	Walker B motif; other site
550537006943	arginine finger; other site
550537006944	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
550537006945	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 0.00016
550537006946	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537006947	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 3.2e-127
550537006948	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537006949	phage shock protein PspA; Provisional; Region: PRK10698
550537006950	HMMPfam hit to PF04012, PspA/IM30, score 2.7e-52
550537006951	phage shock protein B; Provisional; Region: pspB; PRK09458
550537006952	HMMPfam hit to PF06667, Phage shock B, score 9.8e-48
550537006953	1 probable transmembrane helix predicted for SEN1344 by TMHMM2.0 at aa 4-26
550537006954	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
550537006955	phage shock protein C; Region: phageshock_pspC; TIGR02978
550537006956	HMMPfam hit to PF04024, PspC, score 2.6e-29
550537006957	1 probable transmembrane helix predicted for SEN1345 by TMHMM2.0 at aa 39-61
550537006958	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
550537006959	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
550537006960	active site residue [active]
550537006961	1 probable transmembrane helix predicted for SEN1347 by TMHMM2.0 at aa 5-24
550537006962	HMMPfam hit to PF00581, Rhodanese-like, score 1.8e-07
550537006963	Predicted ATPase [General function prediction only]; Region: COG3106
550537006964	HMMPfam hit to PF04317, Protein of unknown function DUF463, YcjX-like protein, score 0
550537006965	PS00017 ATP/GTP-binding site motif A (P-loop).
550537006966	hypothetical protein; Provisional; Region: PRK05415
550537006967	TIGR01620 family protein; Region: hyp_HI0043
550537006968	HMMPfam hit to PF05128, Conserved hypothetical protein CHP01620, score 3.4e-205
550537006969	3 probable transmembrane helices predicted for SEN1349 by TMHMM2.0 at aa 70-89, 99-121 and 210-232
550537006970	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
550537006971	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
550537006972	putative aromatic amino acid binding site; other site
550537006973	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537006974	Walker A motif; other site
550537006975	ATP binding site [chemical binding]; other site
550537006976	Walker B motif; other site
550537006977	arginine finger; other site
550537006978	HMMPfam hit to PF01842, Amino acid-binding ACT, score 0.00011
550537006979	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 3.3e-113
550537006980	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537006981	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537006982	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537006983	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
550537006984	dimer interface [polypeptide binding]; other site
550537006985	catalytic triad [active]
550537006986	peroxidatic and resolving cysteines [active]
550537006987	HMMPfam hit to PF08534, Redoxin, score 1.4e-48
550537006988	PS01265 Tpx family signature.
550537006989	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
550537006990	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
550537006991	active site
550537006992	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 9.5e-41
550537006993	PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1.
550537006994	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 3.6e-18
550537006995	PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2.
550537006996	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
550537006997	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
550537006998	putative active site [active]
550537006999	Zn binding site [ion binding]; other site
550537007000	HMMPfam hit to PF00246, Peptidase M14, carboxypeptidase A, score 1.7e-27
550537007001	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
550537007002	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
550537007003	peptide binding site [polypeptide binding]; other site
550537007004	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 1.3e-82
550537007005	PS01109 Ribosomal protein L10 signature.
550537007006	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
550537007007	NmrA-like family; Region: NmrA; pfam05368
550537007008	NAD(P) binding site [chemical binding]; other site
550537007009	active site lysine
550537007010	HMMPfam hit to PF05368, NmrA-like, score 9.3e-07
550537007011	1 probable transmembrane helix predicted for SEN1355 by TMHMM2.0 at aa 12-34
550537007012	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537007013	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537007014	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
550537007015	putative effector binding pocket; other site
550537007016	putative dimerization interface [polypeptide binding]; other site
550537007017	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2.3e-16
550537007018	PS00044 Bacterial regulatory proteins, lysR family signature.
550537007019	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.3e-42
550537007020	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537007021	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537007022	active site
550537007023	catalytic tetrad [active]
550537007024	HMMPfam hit to PF00248, Aldo/keto reductase, score 9.4e-102
550537007025	PS00798 Aldo/keto reductase family signature 1.
550537007026	PS00062 Aldo/keto reductase family signature 2.
550537007027	PS00063 Aldo/keto reductase family  active site signature.
550537007028	oxidoreductase; Provisional; Region: PRK12742
550537007029	classical (c) SDRs; Region: SDR_c; cd05233
550537007030	NAD(P) binding site [chemical binding]; other site
550537007031	active site
550537007032	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 2.8e-25
550537007033	PS00061 Short-chain dehydrogenases/reductases family signature.
550537007034	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
550537007035	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537007036	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 1.8e-10
550537007037	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
550537007038	HMMPfam hit to PF06004, Protein of unknown function DUF903, bacterial, score 1.4e-39
550537007039	1 probable transmembrane helix predicted for SEN1360 by TMHMM2.0 at aa 5-27
550537007040	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007041	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
550537007042	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537007043	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
550537007044	HMMPfam hit to PF06445, Bacterial transcription activator, effector binding, score 1.1e-26
550537007045	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 1.1e-11
550537007046	PS00041 Bacterial regulatory proteins, araC family signature.
550537007047	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.00055
550537007048	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
550537007049	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
550537007050	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
550537007051	B3/4 domain; Region: B3_4; pfam03483
550537007052	HMMPfam hit to PF03483, B3/4, score 1.6e-07
550537007053	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
550537007054	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537007055	non-specific DNA binding site [nucleotide binding]; other site
550537007056	salt bridge; other site
550537007057	sequence-specific DNA binding site [nucleotide binding]; other site
550537007058	Cupin domain; Region: Cupin_2; pfam07883
550537007059	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 2.3e-11
550537007060	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 1.9e-15
550537007061	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
550537007062	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537007063	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 1.6e-75
550537007064	PS01246 Uncharacterized protein family UPF0003 signature.
550537007065	5 probable transmembrane helices predicted for SEN1368 by TMHMM2.0 at aa 10-30, 39-61, 76-98, 117-134 and 138-160
550537007066	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007067	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
550537007068	2 probable transmembrane helices predicted for SEN1369 by TMHMM2.0 at aa 13-35 and 60-82
550537007069	universal stress protein UspE; Provisional; Region: PRK11175
550537007070	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
550537007071	Ligand Binding Site [chemical binding]; other site
550537007072	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
550537007073	Ligand Binding Site [chemical binding]; other site
550537007074	HMMPfam hit to PF00582, UspA, score 1.3e-12
550537007075	HMMPfam hit to PF00582, UspA, score 4.5e-17
550537007076	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
550537007077	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
550537007078	ligand binding site [chemical binding]; other site
550537007079	flexible hinge region; other site
550537007080	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
550537007081	putative switch regulator; other site
550537007082	non-specific DNA interactions [nucleotide binding]; other site
550537007083	DNA binding site [nucleotide binding]
550537007084	sequence specific DNA binding site [nucleotide binding]; other site
550537007085	putative cAMP binding site [chemical binding]; other site
550537007086	HMMPfam hit to PF00325, Bacterial regulatory protein, Crp, score 1.5e-16
550537007087	PS00042 Bacterial regulatory proteins, crp family signature.
550537007088	HMMPfam hit to PF00027, Cyclic nucleotide-binding, score 1.3e-20
550537007089	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
550537007090	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
550537007091	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
550537007092	DNA binding site [nucleotide binding]
550537007093	active site
550537007094	HMMPfam hit to PF01035, Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding, score 2e-59
550537007095	PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
550537007096	HMMPfam hit to PF02870, Methylguanine DNA methyltransferase, ribonuclease-like, score 7.1e-22
550537007097	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
550537007098	Smr domain; Region: Smr; pfam01713
550537007099	HMMPfam hit to PF01713, Smr protein/MutS2 C-terminal, score 5.8e-29
550537007100	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007101	HAMP domain; Region: HAMP; pfam00672
550537007102	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
550537007103	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537007104	dimer interface [polypeptide binding]; other site
550537007105	putative CheW interface [polypeptide binding]; other site
550537007106	2 probable transmembrane helices predicted for SEN1374 by TMHMM2.0 at aa 7-29 and 33-55
550537007107	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 0.00089
550537007108	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 4.8e-68
550537007109	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
550537007110	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
550537007111	Cl binding site [ion binding]; other site
550537007112	oligomer interface [polypeptide binding]; other site
550537007113	HMMPfam hit to PF01544, Mg2+ transporter protein, CorA-like, score 0.00018
550537007114	2 probable transmembrane helices predicted for SEN1375 by TMHMM2.0 at aa 272-294 and 299-321
550537007115	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
550537007116	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
550537007117	ATP binding site [chemical binding]; other site
550537007118	Mg++ binding site [ion binding]; other site
550537007119	motif III; other site
550537007120	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537007121	nucleotide binding region [chemical binding]; other site
550537007122	ATP-binding site [chemical binding]; other site
550537007123	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
550537007124	putative RNA binding site [nucleotide binding]; other site
550537007125	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 7.1e-67
550537007126	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007127	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
550537007128	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 4.9e-32
550537007129	HMMPfam hit to PF03880, DbpA, RNA-binding, score 3.1e-33
550537007130	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
550537007131	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
550537007132	Ligand Binding Site [chemical binding]; other site
550537007133	HMMPfam hit to PF01171, PP-loop, score 6.7e-07
550537007134	prophage SE14
550537007135	this CDS has suffered a deletion event removing the first ~300 codons
550537007136	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 3.9e-08
550537007137	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
550537007138	HMMPfam hit to PF06630, Enterobacterial exodeoxyribonuclease VIII, score 1.6e-138
550537007139	PS00018 EF-hand calcium-binding domain.
550537007140	PS00136 Serine proteases, subtilase family, aspartic acid active site.
550537007141	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
550537007142	Superinfection exclusion protein B; Region: SieB; pfam14163
550537007143	2 probable transmembrane helices predicted for SEN1382 by TMHMM2.0 at aa 21-43 and 63-85
550537007144	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537007145	non-specific DNA binding site [nucleotide binding]; other site
550537007146	salt bridge; other site
550537007147	sequence-specific DNA binding site [nucleotide binding]; other site
550537007148	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 6e-06
550537007149	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
550537007150	HMMPfam hit to PF06163, Protein of unknown function DUF977, bacterial, score 1.3e-41
550537007151	4 probable transmembrane helices predicted for SEN1385 by TMHMM2.0 at aa 30-49, 54-76, 116-138 and 153-175
550537007152	Hok/gef family; Region: HOK_GEF; pfam01848
550537007153	HMMPfam hit to PF01848, Hok/gef cell toxic protein, score 4e-27
550537007154	1 probable transmembrane helix predicted for SEN1387 by TMHMM2.0 at aa 25-44
550537007155	PS00556 Hok/gef family cell toxic proteins signature.
550537007156	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
550537007157	HMMPfam hit to PF07105, Protein of unknown function DUF1367, score 5.1e-143
550537007158	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
550537007159	HMMPfam hit to PF07102, Protein of unknown function DUF1364, score 2.7e-67
550537007160	PS00190 Cytochrome c family heme-binding site signature.
550537007161	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
550537007162	HMMPfam hit to PF06576, Protein of unknown function DUF1133, score 3e-128
550537007163	tellurite resistance protein terB; Region: terB; cd07176
550537007164	putative metal binding site [ion binding]; other site
550537007165	Protein of unknown function (DUF754); Region: DUF754; pfam05449
550537007166	HMMPfam hit to PF05449, Protein of unknown function DUF754, score 2.3e-27
550537007167	3 probable transmembrane helices predicted for SEN1394 by TMHMM2.0 at aa 10-27, 36-58 and 63-85
550537007168	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
550537007169	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
550537007170	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
550537007171	HMMPfam hit to PF05838, Protein of unknown function DUF847, score 4e-95
550537007172	1 probable transmembrane helix predicted for SEN1396 by TMHMM2.0 at aa 13-32
550537007173	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007174	part of a duplicated sequence
550537007175	this CDS has suffered a deletion event removing most of the 5' end
550537007176	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 2e-06
550537007177	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
550537007178	HMMPfam hit to PF00893, Small multidrug resistance protein, score 1.3e-37
550537007179	4 probable transmembrane helices predicted for SEN1399 by TMHMM2.0 at aa 43-60, 70-89, 96-118 and 128-145
550537007180	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
550537007181	Ligand Binding Site [chemical binding]; other site
550537007182	HMMPfam hit to PF00582, UspA, score 3.1e-20
550537007183	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
550537007184	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
550537007185	dimer interface [polypeptide binding]; other site
550537007186	PYR/PP interface [polypeptide binding]; other site
550537007187	TPP binding site [chemical binding]; other site
550537007188	substrate binding site [chemical binding]; other site
550537007189	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
550537007190	Domain of unknown function; Region: EKR; smart00890
550537007191	4Fe-4S binding domain; Region: Fer4_6; pfam12837
550537007192	4Fe-4S binding domain; Region: Fer4; pfam00037
550537007193	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
550537007194	TPP-binding site [chemical binding]; other site
550537007195	dimer interface [polypeptide binding]; other site
550537007196	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding, score 3.9e-09
550537007197	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 7.9e-05
550537007198	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537007199	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 4.2e-06
550537007200	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537007201	HMMPfam hit to PF01558, Pyruvate ferredoxin/flavodoxin oxidoreductase, score 2.4e-80
550537007202	PS00024 Hemopexin domain signature.
550537007203	HMMPfam hit to PF01855, Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal, score 3.1e-123
550537007204	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
550537007205	Domain of unknown function (DUF333); Region: DUF333; pfam03891
550537007206	heat-inducible protein; Provisional; Region: PRK10449
550537007207	HMMPfam hit to PF03724, Protein of unknown function DUF306, Meta and HslJ, score 5e-33
550537007208	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007209	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
550537007210	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
550537007211	putative ligand binding site [chemical binding]; other site
550537007212	putative NAD binding site [chemical binding]; other site
550537007213	catalytic site [active]
550537007214	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region, score 4.4e-38
550537007215	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding, score 1.1e-71
550537007216	PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
550537007217	PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
550537007218	PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature.
550537007219	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007220	hypothetical protein; Provisional; Region: PRK10695
550537007221	1 probable transmembrane helix predicted for SEN1406 by TMHMM2.0 at aa 7-29
550537007222	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
550537007223	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007224	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
550537007225	1 probable transmembrane helix predicted for SEN1408 by TMHMM2.0 at aa 5-24
550537007226	HMMPfam hit to PF07027, Uncharacterised conserved protein UCP025560, score 1.8e-65
550537007227	Uncharacterized conserved protein [Function unknown]; Region: COG3791
550537007228	HMMPfam hit to PF04828, Glutathione-dependent formaldehyde-activating, GFA, score 1.1e-28
550537007229	azoreductase; Reviewed; Region: PRK00170
550537007230	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
550537007231	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
550537007232	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537007233	ATP binding site [chemical binding]; other site
550537007234	putative Mg++ binding site [ion binding]; other site
550537007235	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537007236	nucleotide binding region [chemical binding]; other site
550537007237	ATP-binding site [chemical binding]; other site
550537007238	Helicase associated domain (HA2); Region: HA2; pfam04408
550537007239	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
550537007240	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
550537007241	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007242	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 7e-14
550537007243	HMMPfam hit to PF04408, Helicase-associated region, score 4e-29
550537007244	HMMPfam hit to PF07717, Region of unknown function DUF1605, score 4.2e-21
550537007245	Uncharacterized conserved protein [Function unknown]; Region: COG1434
550537007246	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
550537007247	putative active site [active]
550537007248	HMMPfam hit to PF02698, Protein of unknown function DUF218, score 1.2e-28
550537007249	cytochrome b561; Provisional; Region: PRK11513
550537007250	HMMPfam hit to PF01292, Cytochrome B561, bacterial, score 5.5e-64
550537007251	4 probable transmembrane helices predicted for SEN1413 by TMHMM2.0 at aa 5-27, 40-62, 83-105 and 140-162
550537007252	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537007253	S-adenosylmethionine binding site [chemical binding]; other site
550537007254	HMMPfam hit to PF08242, Methyltransferase type 12, score 3.9e-14
550537007255	note the frameshift mutation following codon 269
550537007256	3 probable transmembrane helices predicted for SEN1415 by TMHMM2.0 at aa 21-43, 47-66 and 73-90
550537007257	5 probable transmembrane helices predicted for SEN1416 by TMHMM2.0 at aa 20-39, 90-112, 143-162, 172-194 and 215-237
550537007258	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007259	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537007260	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537007261	dimer interface [polypeptide binding]; other site
550537007262	conserved gate region; other site
550537007263	putative PBP binding loops; other site
550537007264	ABC-ATPase subunit interface; other site
550537007265	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 2.2e-10
550537007266	5 probable transmembrane helices predicted for SEN1417 by TMHMM2.0 at aa 30-49, 61-83, 93-115, 136-158 and 192-214
550537007267	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537007268	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
550537007269	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537007270	Walker A/P-loop; other site
550537007271	ATP binding site [chemical binding]; other site
550537007272	Q-loop/lid; other site
550537007273	ABC transporter signature motif; other site
550537007274	Walker B; other site
550537007275	D-loop; other site
550537007276	H-loop/switch region; other site
550537007277	HMMPfam hit to PF00005, ABC transporter related, score 2.9e-50
550537007278	PS00211 ABC transporters family signature.
550537007279	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007280	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537007281	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537007282	dimer interface [polypeptide binding]; other site
550537007283	conserved gate region; other site
550537007284	putative PBP binding loops; other site
550537007285	ABC-ATPase subunit interface; other site
550537007286	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 5.4e-15
550537007287	4 probable transmembrane helices predicted for SEN1419 by TMHMM2.0 at aa 7-40, 55-77, 79-101 and 186-208
550537007288	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537007289	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
550537007290	substrate binding pocket [chemical binding]; other site
550537007291	membrane-bound complex binding site; other site
550537007292	hinge residues; other site
550537007293	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 5.5e-30
550537007294	Predicted membrane protein [Function unknown]; Region: COG3326
550537007295	3 probable transmembrane helices predicted for SEN1421 by TMHMM2.0 at aa 2-21, 25-42 and 89-111
550537007296	HMMPfam hit to PF06961, Protein of unknown function DUF1294, score 1.1e-34
550537007297	Sif protein; Region: Sif; cl11505
550537007298	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
550537007299	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
550537007300	active site
550537007301	catalytic triad [active]
550537007302	oxyanion hole [active]
550537007303	HMMPfam hit to PF06767, Sif, score 4.4e-06
550537007304	5 probable transmembrane helices predicted for SEN1423 by TMHMM2.0 at aa 12-34, 54-76, 88-110, 114-136 and 155-177
550537007305	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
550537007306	putative metal binding site [ion binding]; other site
550537007307	putative homodimer interface [polypeptide binding]; other site
550537007308	putative homotetramer interface [polypeptide binding]; other site
550537007309	putative homodimer-homodimer interface [polypeptide binding]; other site
550537007310	putative allosteric switch controlling residues; other site
550537007311	HMMPfam hit to PF02583, Protein of unknown function DUF156, score 1.7e-34
550537007312	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
550537007313	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
550537007314	substrate binding site [chemical binding]; other site
550537007315	catalytic Zn binding site [ion binding]; other site
550537007316	NAD binding site [chemical binding]; other site
550537007317	structural Zn binding site [ion binding]; other site
550537007318	dimer interface [polypeptide binding]; other site
550537007319	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 2.8e-39
550537007320	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537007321	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 2.9e-33
550537007322	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
550537007323	dimer interface [polypeptide binding]; other site
550537007324	ligand binding site [chemical binding]; other site
550537007325	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
550537007326	HAMP domain; Region: HAMP; pfam00672
550537007327	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537007328	dimer interface [polypeptide binding]; other site
550537007329	putative CheW interface [polypeptide binding]; other site
550537007330	2 probable transmembrane helices predicted for SEN1426 by TMHMM2.0 at aa 26-48 and 203-225
550537007331	HMMPfam hit to PF02203, Ligand binding Tar, score 1.9e-30
550537007332	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1.2e-14
550537007333	PS00538 Bacterial chemotaxis sensory transducers signature.
550537007334	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 9.4e-114
550537007335	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
550537007336	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537007337	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537007338	dimerization interface [polypeptide binding]; other site
550537007339	HMMPfam hit to PF03466, LysR, substrate-binding, score 5.9e-37
550537007340	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 5.1e-19
550537007341	PS00044 Bacterial regulatory proteins, lysR family signature.
550537007342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
550537007343	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
550537007344	PS00237 G-protein coupled receptors signature.
550537007345	HMMPfam hit to PF07063, Protein of unknown function DUF1338, score 3.4e-71
550537007346	PS00294 Prenyl group binding site (CAAX box).
550537007347	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
550537007348	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
550537007349	substrate binding pocket [chemical binding]; other site
550537007350	catalytic triad [active]
550537007351	HMMPfam hit to PF00135, Carboxylesterase, type B, score 1.6e-100
550537007352	PS00941 Carboxylesterases type-B signature 2.
550537007353	PS00122 Carboxylesterases type-B serine active site.
550537007354	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
550537007355	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
550537007356	HMMPfam hit to PF04349, Glucan biosynthesis, periplasmic, MdoG C-terminal, score 2.2e-167
550537007357	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007358	Uncharacterized conserved protein [Function unknown]; Region: COG2353
550537007359	HMMPfam hit to PF04264, Lipid/polyisoprenoid-binding, YceI-like, score 1.3e-48
550537007360	Transcriptional regulators [Transcription]; Region: FadR; COG2186
550537007361	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537007362	DNA-binding site [nucleotide binding]; DNA binding site
550537007363	FCD domain; Region: FCD; pfam07729
550537007364	HMMPfam hit to PF07729, GntR, C-terminal, score 3.6e-25
550537007365	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 2.2e-18
550537007366	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
550537007367	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
550537007368	putative NAD(P) binding site [chemical binding]; other site
550537007369	catalytic Zn binding site [ion binding]; other site
550537007370	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 5.4e-33
550537007371	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 4.8e-45
550537007372	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007373	D-galactonate transporter; Region: 2A0114; TIGR00893
550537007374	putative substrate translocation pore; other site
550537007375	12 probable transmembrane helices predicted for SEN1434 by TMHMM2.0 at aa 75-97, 112-134, 141-163, 168-190, 211-233, 237-259, 309-331, 346-365, 378-400, 406-428, 441-463 and 473-492
550537007376	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5.6e-65
550537007377	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
550537007378	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
550537007379	NADP binding site [chemical binding]; other site
550537007380	homodimer interface [polypeptide binding]; other site
550537007381	active site
550537007382	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 7.7e-33
550537007383	PS00061 Short-chain dehydrogenases/reductases family signature.
550537007384	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
550537007385	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
550537007386	metal binding site [ion binding]; metal-binding site
550537007387	substrate binding pocket [chemical binding]; other site
550537007388	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 2.7e-29
550537007389	PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1.
550537007390	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 1.2e-16
550537007391	PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2.
550537007392	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537007393	Coenzyme A binding pocket [chemical binding]; other site
550537007394	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 3.1e-20
550537007395	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537007396	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
550537007397	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537007398	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 8.8e-72
550537007399	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 1.3e-23
550537007400	PS00894 Bacterial regulatory proteins, deoR family signature.
550537007401	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
550537007402	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
550537007403	substrate binding site [chemical binding]; other site
550537007404	hexamer interface [polypeptide binding]; other site
550537007405	metal binding site [ion binding]; metal-binding site
550537007406	HMMPfam hit to PF00834, Ribulose-phosphate 3-epimerase, score 6.3e-87
550537007407	PS01086 Ribulose-phosphate 3-epimerase family signature 2.
550537007408	PS01085 Ribulose-phosphate 3-epimerase family signature 1.
550537007409	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537007410	active site
550537007411	phosphorylation site [posttranslational modification]
550537007412	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 9.4e-52
550537007413	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
550537007414	HMMPfam hit to PF03437, Photosystem I assembly BtpA, score 5.9e-148
550537007415	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
550537007416	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
550537007417	9 probable transmembrane helices predicted for SEN1442 by TMHMM2.0 at aa 5-27, 32-54, 82-104, 125-147, 216-235, 242-264, 298-320, 349-371 and 408-430
550537007418	HMMPfam hit to PF03611, Phosphotransferase system, galactitol-specific IIC component, score 4.4e-196
550537007419	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
550537007420	active site
550537007421	P-loop; other site
550537007422	phosphorylation site [posttranslational modification]
550537007423	HMMPfam hit to PF02302, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, score 9e-24
550537007424	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
550537007425	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
550537007426	oligomer interface [polypeptide binding]; other site
550537007427	active site
550537007428	metal binding site [ion binding]; metal-binding site
550537007429	HMMPfam hit to PF05343, Peptidase M42, score 5.6e-140
550537007430	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
550537007431	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537007432	Coenzyme A binding pocket [chemical binding]; other site
550537007433	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 3.1e-09
550537007434	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
550537007435	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
550537007436	putative trimer interface [polypeptide binding]; other site
550537007437	putative CoA binding site [chemical binding]; other site
550537007438	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
550537007439	putative trimer interface [polypeptide binding]; other site
550537007440	putative CoA binding site [chemical binding]; other site
550537007441	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 76
550537007442	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 8.3
550537007443	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 69
550537007444	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 67
550537007445	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 92
550537007446	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 67
550537007447	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
550537007448	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
550537007449	gating phenylalanine in ion channel; other site
550537007450	10 probable transmembrane helices predicted for SEN1447 by TMHMM2.0 at aa 13-32, 47-69, 82-104, 108-130, 143-165, 169-188, 200-222, 237-254, 261-280 and 290-312
550537007451	HMMPfam hit to PF03595, C4-dicarboxylate transporter/malic acid transport protein, score 4.2e-82
550537007452	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007453	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007454	tellurite resistance protein TehB; Provisional; Region: PRK11207
550537007455	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537007456	S-adenosylmethionine binding site [chemical binding]; other site
550537007457	HMMPfam hit to PF03848, Tellurite resistance methyltransferase, TehB, core, score 8.6e-150
550537007458	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
550537007459	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007460	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
550537007461	benzoate transporter; Region: benE; TIGR00843
550537007462	11 probable transmembrane helices predicted for SEN1450 by TMHMM2.0 at aa 10-30, 43-65, 93-112, 119-138, 143-165, 172-194, 209-231, 252-274, 289-311, 318-340 and 360-382
550537007463	HMMPfam hit to PF03594, Benzoate membrane transport protein, score 4.6e-199
550537007464	PS00041 Bacterial regulatory proteins, araC family signature.
550537007465	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
550537007466	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537007467	non-specific DNA binding site [nucleotide binding]; other site
550537007468	salt bridge; other site
550537007469	sequence-specific DNA binding site [nucleotide binding]; other site
550537007470	Cupin domain; Region: Cupin_2; pfam07883
550537007471	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 1.5e-15
550537007472	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 2.6e-07
550537007473	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
550537007474	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
550537007475	Peptidase family U32; Region: Peptidase_U32; pfam01136
550537007476	Collagenase; Region: DUF3656; pfam12392
550537007477	HMMPfam hit to PF01136, Peptidase U32, score 4.6e-99
550537007478	PS01276 Peptidase family U32 signature.
550537007479	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
550537007480	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
550537007481	HMMPfam hit to PF06767, Sif, score 2.5e-26
550537007482	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007483	2 probable transmembrane helices predicted for SEN1455 by TMHMM2.0 at aa 33-67 and 82-104
550537007484	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
550537007485	HMMPfam hit to PF01427, Peptidase M15D, vanX D-ala-D-ala dipeptidase, score 1.1e-40
550537007486	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
550537007487	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537007488	DNA-binding site [nucleotide binding]; DNA binding site
550537007489	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537007490	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537007491	homodimer interface [polypeptide binding]; other site
550537007492	catalytic residue [active]
550537007493	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 4.3e-16
550537007494	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 7e-12
550537007495	1-pyrroline dehydrogenase; Region: ABALDH; TIGR03374
550537007496	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
550537007497	tetrameric interface [polypeptide binding]; other site
550537007498	NAD binding site [chemical binding]; other site
550537007499	catalytic residues [active]
550537007500	substrate binding site [chemical binding]; other site
550537007501	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 1.2e-221
550537007502	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537007503	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
550537007504	2 probable transmembrane helices predicted for SEN1459 by TMHMM2.0 at aa 33-55 and 62-84
550537007505	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
550537007506	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
550537007507	HMMPfam hit to PF07520, Predicted virulence protein SrfB, score 0
550537007508	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
550537007509	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
550537007510	5 probable transmembrane helices predicted for SEN1464 by TMHMM2.0 at aa 5-25, 32-54, 69-88, 95-117 and 122-144
550537007511	HMMPfam hit to PF04657, Protein of unknown function DUF606, score 3.7e-50
550537007512	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
550537007513	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
550537007514	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 5.3e-23
550537007515	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
550537007516	Prostaglandin dehydrogenases; Region: PGDH; cd05288
550537007517	NAD(P) binding site [chemical binding]; other site
550537007518	substrate binding site [chemical binding]; other site
550537007519	dimer interface [polypeptide binding]; other site
550537007520	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 4.2e-18
550537007521	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
550537007522	DNA-binding site [nucleotide binding]; DNA binding site
550537007523	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
550537007524	FCD domain; Region: FCD; pfam07729
550537007525	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 6.1e-13
550537007526	HMMPfam hit to PF07729, GntR, C-terminal, score 2e-06
550537007527	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
550537007528	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537007529	N-terminal plug; other site
550537007530	ligand-binding site [chemical binding]; other site
550537007531	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 8e-34
550537007532	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 1.7e-24
550537007533	Uncharacterized conserved protein [Function unknown]; Region: COG3391
550537007534	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
550537007535	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007536	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
550537007537	HMMPfam hit to PF06004, Protein of unknown function DUF903, bacterial, score 1.9e-47
550537007538	1 probable transmembrane helix predicted for SEN1470 by TMHMM2.0 at aa 4-26
550537007539	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007540	L-asparagine permease; Provisional; Region: PRK15049
550537007541	HMMPfam hit to PF00324, Amino acid permease-associated region, score 2.1e-179
550537007542	12 probable transmembrane helices predicted for SEN1471 by TMHMM2.0 at aa 37-59, 64-86, 107-129, 144-166, 171-193, 218-240, 260-282, 302-324, 351-373, 377-399, 420-442 and 446-468
550537007543	PS00218 Amino acid permeases signature.
550537007544	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
550537007545	HMMPfam hit to PF00797, N-acetyltransferase, score 1.6e-118
550537007546	hypothetical protein; Provisional; Region: PRK10281
550537007547	HMMPfam hit to PF02567, Phenazine biosynthesis PhzC/PhzF protein, score 3.9e-118
550537007548	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
550537007549	HMMPfam hit to PF02665, Nitrate reductase, gamma subunit, score 5.4e-122
550537007550	5 probable transmembrane helices predicted for SEN1475 by TMHMM2.0 at aa 5-27, 48-70, 90-112, 128-150 and 185-207
550537007551	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
550537007552	HMMPfam hit to PF02613, Nitrate reductase, delta subunit, score 7.7e-85
550537007553	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
550537007554	PS00190 Cytochrome c family heme-binding site signature.
550537007555	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
550537007556	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
550537007557	[4Fe-4S] binding site [ion binding]; other site
550537007558	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537007559	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537007560	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537007561	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
550537007562	molybdopterin cofactor binding site; other site
550537007563	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 7.9e-26
550537007564	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 7.6e-144
550537007565	PS00490 Prokaryotic molybdopterin oxidoreductases signature 2.
550537007566	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007567	PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
550537007568	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
550537007569	12 probable transmembrane helices predicted for SEN1479 by TMHMM2.0 at aa 36-58, 73-95, 102-121, 131-153, 174-196, 211-233, 254-276, 286-308, 313-335, 345-367, 401-418 and 433-455
550537007570	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.1e-13
550537007571	TetR family transcriptional regulator; Provisional; Region: PRK14996
550537007572	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537007573	1 probable transmembrane helix predicted for SEN1480 by TMHMM2.0 at aa 151-170
550537007574	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 4.9e-12
550537007575	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
550537007576	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007577	putative substrate translocation pore; other site
550537007578	14 probable transmembrane helices predicted for SEN1481 by TMHMM2.0 at aa 7-29, 44-66, 73-92, 97-119, 132-154, 158-180, 193-212, 222-240, 261-283, 298-320, 322-344, 354-376, 389-411 and 468-490
550537007579	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.3e-48
550537007580	Uncharacterized conserved protein [Function unknown]; Region: COG3791
550537007581	HMMPfam hit to PF04828, Glutathione-dependent formaldehyde-activating, GFA, score 2.4e-18
550537007582	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537007583	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
550537007584	trimer interface [polypeptide binding]; other site
550537007585	eyelet of channel; other site
550537007586	HMMPfam hit to PF00267, Porin, Gram-negative type, score 6.2e-202
550537007587	PS00576 General diffusion Gram-negative porins signature.
550537007588	1 probable transmembrane helix predicted for SEN1483 by TMHMM2.0 at aa 16-38
550537007589	aromatic amino acid exporter; Provisional; Region: PRK11689
550537007590	9 probable transmembrane helices predicted for SEN1484 by TMHMM2.0 at aa 15-34, 46-68, 72-94, 101-119, 129-151, 163-185, 190-212, 219-241 and 251-270
550537007591	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2e-06
550537007592	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
550537007593	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
550537007594	[4Fe-4S] binding site [ion binding]; other site
550537007595	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537007596	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
550537007597	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
550537007598	molybdopterin cofactor binding site; other site
550537007599	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 9.8e-22
550537007600	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 2.3e-33
550537007601	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 4.1e-14
550537007602	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
550537007603	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
550537007604	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 3.1e-05
550537007605	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537007606	HMMPfam hit to PF09163, Formate dehydrogenase, transmembrane, score 5.9e-22
550537007607	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
550537007608	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
550537007609	4 probable transmembrane helices predicted for SEN1487 by TMHMM2.0 at aa 13-35, 50-72, 112-134 and 149-171
550537007610	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
550537007611	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
550537007612	NAD binding site [chemical binding]; other site
550537007613	substrate binding site [chemical binding]; other site
550537007614	catalytic Zn binding site [ion binding]; other site
550537007615	tetramer interface [polypeptide binding]; other site
550537007616	structural Zn binding site [ion binding]; other site
550537007617	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 5.3e-42
550537007618	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 9e-45
550537007619	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537007620	PS00190 Cytochrome c family heme-binding site signature.
550537007621	malate dehydrogenase; Provisional; Region: PRK13529
550537007622	Malic enzyme, N-terminal domain; Region: malic; pfam00390
550537007623	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
550537007624	NAD(P) binding site [chemical binding]; other site
550537007625	HMMPfam hit to PF03949, Malic enzyme, NAD-binding, score 3.5e-142
550537007626	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007627	PS00331 Malic enzymes signature.
550537007628	HMMPfam hit to PF00390, Malic enzyme, N-terminal, score 1.6e-130
550537007629	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007630	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
550537007631	HMMPfam hit to PF08136, Ribosomal protein, S22, score 2.6e-38
550537007632	biofilm-dependent modulation protein; Provisional; Region: PRK11436
550537007633	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
550537007634	HMMPfam hit to PF02566, OsmC-like protein, score 5.2e-28
550537007635	acid-resistance protein; Provisional; Region: hdeB; PRK11566
550537007636	1 probable transmembrane helix predicted for SEN1493 by TMHMM2.0 at aa 4-26
550537007637	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
550537007638	HMMPfam hit to PF06884, Protein of unknown function DUF1264, score 4.3e-142
550537007639	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
550537007640	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
550537007641	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
550537007642	catalytic site [active]
550537007643	active site
550537007644	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
550537007645	HMMPfam hit to PF02922, Glycoside hydrolase, family 13, N-terminal, score 0.05
550537007646	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 4.5e-18
550537007647	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
550537007648	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
550537007649	active site
550537007650	catalytic site [active]
550537007651	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 2.2e-15
550537007652	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
550537007653	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
550537007654	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
550537007655	active site
550537007656	catalytic site [active]
550537007657	HMMPfam hit to PF02922, Glycoside hydrolase, family 13, N-terminal, score 1.6e-30
550537007658	PS00018 EF-hand calcium-binding domain.
550537007659	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 4.4e-14
550537007660	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
550537007661	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537007662	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537007663	homodimer interface [polypeptide binding]; other site
550537007664	catalytic residue [active]
550537007665	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 7.5e-30
550537007666	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
550537007667	10 probable transmembrane helices predicted for SEN1499 by TMHMM2.0 at aa 13-35, 77-99, 112-134, 139-161, 195-217, 237-256, 263-285, 328-350, 357-379 and 444-466
550537007668	HMMPfam hit to PF03553, Na+/H+ antiporter NhaC, score 4.2e-83
550537007669	Transcriptional regulators [Transcription]; Region: PurR; COG1609
550537007670	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537007671	DNA binding site [nucleotide binding]
550537007672	domain linker motif; other site
550537007673	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
550537007674	dimerization interface (closed form) [polypeptide binding]; other site
550537007675	ligand binding site [chemical binding]; other site
550537007676	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 8.5e-14
550537007677	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 4e-11
550537007678	PS00356 Bacterial regulatory proteins, lacI family signature.
550537007679	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
550537007680	HMMPfam hit to PF07377, Protein of unknown function DUF1493, score 2e-37
550537007683	HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 6.6e-15
550537007684	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
550537007685	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
550537007686	HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 5.3e-10
550537007687	HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 1.4e-08
550537007688	Transcriptional regulators [Transcription]; Region: MarR; COG1846
550537007689	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537007690	putative DNA binding site [nucleotide binding]; other site
550537007691	putative Zn2+ binding site [ion binding]; other site
550537007692	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 8.4e-16
550537007693	hypothetical protein; Provisional; Region: PRK06184
550537007694	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
550537007695	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
550537007696	HMMPfam hit to PF01494, Monooxygenase, FAD-binding, score 4.7e-88
550537007697	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007698	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537007699	putative substrate translocation pore; other site
550537007700	11 probable transmembrane helices predicted for SEN1507 by TMHMM2.0 at aa 25-47, 57-79, 86-105, 110-132, 144-166, 171-193, 219-241, 261-283, 295-329, 349-371 and 378-400
550537007701	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4.9e-50
550537007702	PS00216 Sugar transport proteins signature 1.
550537007703	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
550537007704	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
550537007705	1 probable transmembrane helix predicted for SEN1508 by TMHMM2.0 at aa 27-49
550537007706	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007707	D-galactonate transporter; Region: 2A0114; TIGR00893
550537007708	putative substrate translocation pore; other site
550537007709	12 probable transmembrane helices predicted for SEN1509 by TMHMM2.0 at aa 7-26, 46-68, 75-97, 101-123, 135-157, 162-184, 228-250, 265-287, 303-325, 329-350, 362-384 and 394-413
550537007710	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.3e-76
550537007711	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
550537007712	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
550537007713	putative NAD(P) binding site [chemical binding]; other site
550537007714	catalytic Zn binding site [ion binding]; other site
550537007715	structural Zn binding site [ion binding]; other site
550537007716	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 2.6e-46
550537007717	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 5.4e-37
550537007718	Transcriptional regulators [Transcription]; Region: FadR; COG2186
550537007719	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537007720	DNA-binding site [nucleotide binding]; DNA binding site
550537007721	FCD domain; Region: FCD; pfam07729
550537007722	HMMPfam hit to PF07729, GntR, C-terminal, score 1.4e-36
550537007723	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 6.1e-23
550537007724	PS00043 Bacterial regulatory proteins, gntR family signature.
550537007725	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
550537007726	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
550537007727	active site
550537007728	HMMPfam hit to PF02275, Choloylglycine hydrolase, score 8.2e-22
550537007729	1 probable transmembrane helix predicted for SEN1512 by TMHMM2.0 at aa 7-29
550537007730	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007731	hydrogenase 1
550537007732	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
550537007733	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
550537007734	HMMPfam hit to PF08425, NiFe dehydrogenase small subunit, N-terminal, score 9.4e-50
550537007735	1 probable transmembrane helix predicted for SEN1513 by TMHMM2.0 at aa 21-43
550537007736	HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 kDa subunit, score 9.1e-26
550537007737	hydrogenase 1 large subunit; Provisional; Region: PRK10170
550537007738	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
550537007739	HMMPfam hit to PF00374, Nickel-dependent hydrogenase, large subunit, score 0
550537007740	PS00507 Nickel-dependent hydrogenases large subunit signature 1.
550537007741	PS00508 Nickel-dependent hydrogenases large subunit signature 2.
550537007742	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
550537007743	HMMPfam hit to PF01292, Cytochrome B561, bacterial, score 2.4e-62
550537007744	PS00882 Nickel-dependent hydrogenases b-type cytochrome subunit signature 1.
550537007745	4 probable transmembrane helices predicted for SEN1515 by TMHMM2.0 at aa 43-62, 82-104, 151-173 and 203-225
550537007746	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
550537007747	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
550537007748	putative substrate-binding site; other site
550537007749	nickel binding site [ion binding]; other site
550537007750	HMMPfam hit to PF01750, Peptidase A31, hydrogen uptake protein, score 1.8e-44
550537007751	HupF/HypC family; Region: HupF_HypC; cl00394
550537007752	HMMPfam hit to PF01455, Hydrogenase expression/formation protein (HUPF/HYPC), score 3.2e-16
550537007753	PS01097 Hydrogenases expression/synthesis hupF/hypC family signature.
550537007754	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
550537007755	HMMPfam hit to PF07449, Hydrogenase-1 expression HyaE, score 5.1e-55
550537007756	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
550537007757	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
550537007758	Rubredoxin [Energy production and conversion]; Region: COG1773
550537007759	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
550537007760	iron binding site [ion binding]; other site
550537007761	HMMPfam hit to PF04809, HupH hydrogenase expression protein, C-terminal conserved region, score 4.9e-41
550537007762	HMMPfam hit to PF00301, Rubredoxin-type Fe(Cys)4 protein, score 3.8e-23
550537007763	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
550537007764	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007765	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
550537007766	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
550537007767	HMMPfam hit to PF01155, Hydrogenase expression/synthesis, HypA, score 2e-58
550537007768	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537007769	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
550537007770	trimer interface [polypeptide binding]; other site
550537007771	eyelet of channel; other site
550537007772	HMMPfam hit to PF00267, Porin, Gram-negative type, score 1.4e-173
550537007773	PS00576 General diffusion Gram-negative porins signature.
550537007774	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
550537007775	Predicted membrane protein [Function unknown]; Region: COG3781
550537007776	HMMPfam hit to PF05249, Protein of unknown function UPF0187, score 5.1e-171
550537007777	3 probable transmembrane helices predicted for SEN1524 by TMHMM2.0 at aa 39-58, 63-81 and 229-251
550537007778	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
550537007779	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
550537007780	glutaminase; Provisional; Region: PRK00971
550537007781	HMMPfam hit to PF04960, Glutaminase, core, score 9.2e-202
550537007782	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
550537007783	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
550537007784	NAD(P) binding site [chemical binding]; other site
550537007785	catalytic residues [active]
550537007786	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 5.1e-166
550537007787	PS00070 Aldehyde dehydrogenases cysteine active site.
550537007788	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537007789	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537007790	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
550537007791	putative dimerization interface [polypeptide binding]; other site
550537007792	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.2e-16
550537007793	PS00044 Bacterial regulatory proteins, lysR family signature.
550537007794	HMMPfam hit to PF03466, LysR, substrate-binding, score 9e-52
550537007795	putative arabinose transporter; Provisional; Region: PRK03545
550537007796	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007797	putative substrate translocation pore; other site
550537007798	12 probable transmembrane helices predicted for SEN1529 by TMHMM2.0 at aa 12-34, 49-71, 80-99, 109-131, 138-160, 170-189, 210-229, 244-266, 273-295, 299-321, 333-352 and 362-384
550537007799	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 6.1e-47
550537007800	inner membrane protein; Provisional; Region: PRK10995
550537007801	HMMPfam hit to PF01914, Multiple antibiotic resistance (MarC)-related proteins, score 8.7e-95
550537007802	6 probable transmembrane helices predicted for SEN1530 by TMHMM2.0 at aa 10-32, 44-66, 71-93, 117-139, 154-176 and 196-217
550537007803	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
550537007804	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
550537007805	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 3.4e-29
550537007806	PS00190 Cytochrome c family heme-binding site signature.
550537007807	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
550537007808	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537007809	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537007810	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.9e-13
550537007811	PS00041 Bacterial regulatory proteins, araC family signature.
550537007812	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 5.6e-10
550537007813	MarB protein; Region: MarB; pfam13999
550537007814	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
550537007815	EamA-like transporter family; Region: EamA; pfam00892
550537007816	10 probable transmembrane helices predicted for SEN1534 by TMHMM2.0 at aa 7-24, 34-52, 59-81, 91-110, 117-136, 140-162, 174-196, 216-238, 245-264 and 268-290
550537007817	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 3e-16
550537007818	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 1.1e-12
550537007819	putative transporter; Provisional; Region: PRK10054
550537007820	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007821	putative substrate translocation pore; other site
550537007822	12 probable transmembrane helices predicted for SEN1535 by TMHMM2.0 at aa 12-34, 44-66, 75-94, 99-121, 134-156, 160-182, 213-235, 245-264, 271-293, 298-320, 333-355 and 359-381
550537007823	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 6.4e-33
550537007824	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007825	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007826	hypothetical protein; Provisional; Region: PRK10053
550537007827	HMMPfam hit to PF04076, Conserved hypothetical protein CHP00156, score 3e-62
550537007828	hypothetical protein; Validated; Region: PRK03657
550537007829	HMMPfam hit to PF02464, CinA, C-terminal, score 4.8e-62
550537007830	General stress protein [General function prediction only]; Region: GsiB; COG3729
550537007831	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
550537007832	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
550537007833	active site
550537007834	Zn binding site [ion binding]; other site
550537007835	HMMPfam hit to PF01432, Peptidase M3A and M3B, thimet/oligopeptidase F, score 3.6e-177
550537007836	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537007837	malonic semialdehyde reductase; Provisional; Region: PRK10538
550537007838	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
550537007839	putative NAD(P) binding site [chemical binding]; other site
550537007840	homodimer interface [polypeptide binding]; other site
550537007841	homotetramer interface [polypeptide binding]; other site
550537007842	active site
550537007843	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 2.1e-35
550537007844	PS00061 Short-chain dehydrogenases/reductases family signature.
550537007845	Transcriptional regulators [Transcription]; Region: GntR; COG1802
550537007846	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537007847	DNA-binding site [nucleotide binding]; DNA binding site
550537007848	FCD domain; Region: FCD; pfam07729
550537007849	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 5.1e-21
550537007850	PS00043 Bacterial regulatory proteins, gntR family signature.
550537007851	HMMPfam hit to PF07729, GntR, C-terminal, score 4.4e-10
550537007852	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
550537007853	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007854	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
550537007855	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
550537007856	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
550537007857	HMMPfam hit to PF08125, Mannitol dehydrogenase, C-terminal, score 6.2e-126
550537007858	PS00974 Mannitol dehydrogenases signature.
550537007859	HMMPfam hit to PF01232, Mannitol dehydrogenase rossman, N-terminal, score 3.1e-87
550537007860	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007861	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007862	metabolite-proton symporter; Region: 2A0106; TIGR00883
550537007863	putative substrate translocation pore; other site
550537007864	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 7e-25
550537007865	putative oxidoreductase; Provisional; Region: PRK10083
550537007866	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
550537007867	putative NAD(P) binding site [chemical binding]; other site
550537007868	catalytic Zn binding site [ion binding]; other site
550537007869	structural Zn binding site [ion binding]; other site
550537007870	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 7.2e-22
550537007871	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 6.2e-53
550537007872	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537007873	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
550537007874	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
550537007875	putative active site pocket [active]
550537007876	putative metal binding site [ion binding]; other site
550537007877	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 2.1e-16
550537007878	PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2.
550537007879	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 2.2e-58
550537007880	PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1.
550537007881	hypothetical protein; Provisional; Region: PRK02237
550537007882	HMMPfam hit to PF02694, Protein of unknown function UPF0060, score 1.1e-69
550537007883	4 probable transmembrane helices predicted for SEN1546 by TMHMM2.0 at aa 7-26, 30-52, 59-78 and 83-105
550537007884	hypothetical protein; Provisional; Region: PRK13659
550537007885	HMMPfam hit to PF06932, Protein of unknown function DUF1283, score 3e-70
550537007886	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
550537007887	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537007888	Coenzyme A binding pocket [chemical binding]; other site
550537007889	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
550537007890	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 1.7e-20
550537007891	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
550537007892	HMMPfam hit to PF06788, Protein of unknown function UPF0257, score 2.3e-194
550537007893	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007894	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
550537007895	HMMPfam hit to PF06649, Protein of unknown function DUF1161, score 8e-45
550537007896	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
550537007897	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
550537007898	putative [Fe4-S4] binding site [ion binding]; other site
550537007899	putative molybdopterin cofactor binding site [chemical binding]; other site
550537007900	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
550537007901	putative molybdopterin cofactor binding site; other site
550537007902	1 probable transmembrane helix predicted for SEN1551 by TMHMM2.0 at aa 21-43
550537007903	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 2.3e-12
550537007904	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 6.6e-141
550537007905	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537007906	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 4.3e-35
550537007907	PS00932 Prokaryotic molybdopterin oxidoreductases signature 3.
550537007908	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
550537007909	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
550537007910	putative [Fe4-S4] binding site [ion binding]; other site
550537007911	putative molybdopterin cofactor binding site [chemical binding]; other site
550537007912	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
550537007913	putative molybdopterin cofactor binding site; other site
550537007914	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 1.3e-12
550537007915	PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
550537007916	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 2.2e-125
550537007917	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 3.2e-34
550537007918	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
550537007919	4Fe-4S binding domain; Region: Fer4; pfam00037
550537007920	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007921	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.5e-07
550537007922	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537007923	PS00190 Cytochrome c family heme-binding site signature.
550537007924	PS00190 Cytochrome c family heme-binding site signature.
550537007925	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
550537007926	HMMPfam hit to PF04976, DMSO reductase anchor subunit (DmsC), score 6.6e-149
550537007927	8 probable transmembrane helices predicted for SEN1554 by TMHMM2.0 at aa 10-32, 44-66, 88-107, 114-136, 151-173, 180-202, 222-244 and 251-273
550537007928	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
550537007929	HMMPfam hit to PF06192, Cytoplasmic chaperone TorD, score 2.5e-59
550537007930	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537007931	dimer interface [polypeptide binding]; other site
550537007932	conserved gate region; other site
550537007933	putative PBP binding loops; other site
550537007934	ABC-ATPase subunit interface; other site
550537007935	6 probable transmembrane helices predicted for SEN1556 by TMHMM2.0 at aa 9-31, 46-68, 89-111, 126-145, 173-195 and 205-227
550537007936	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 7.7e-25
550537007937	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537007938	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
550537007939	HMMPfam hit to PF04069, Substrate-binding region of ABC-type glycine betaine transport system, score 3.1e-90
550537007940	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537007941	dimer interface [polypeptide binding]; other site
550537007942	conserved gate region; other site
550537007943	ABC-ATPase subunit interface; other site
550537007944	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 6.2e-23
550537007945	5 probable transmembrane helices predicted for SEN1558 by TMHMM2.0 at aa 22-44, 51-73, 78-100, 149-171 and 181-203
550537007946	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537007947	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
550537007948	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
550537007949	Walker A/P-loop; other site
550537007950	ATP binding site [chemical binding]; other site
550537007951	Q-loop/lid; other site
550537007952	ABC transporter signature motif; other site
550537007953	Walker B; other site
550537007954	D-loop; other site
550537007955	H-loop/switch region; other site
550537007956	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
550537007957	HMMPfam hit to PF00005, ABC transporter related, score 5.3e-59
550537007958	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007959	PS00211 ABC transporters family signature.
550537007960	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 8.7e-16
550537007961	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
550537007962	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
550537007963	Cl- selectivity filter; other site
550537007964	Cl- binding residues [ion binding]; other site
550537007965	pore gating glutamate residue; other site
550537007966	dimer interface [polypeptide binding]; other site
550537007967	10 probable transmembrane helices predicted for SEN1560 by TMHMM2.0 at aa 12-34, 66-83, 158-180, 185-207, 234-256, 271-293, 300-322, 332-354, 361-383 and 398-416
550537007968	HMMPfam hit to PF00654, Chloride channel, core, score 5e-16
550537007969	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007970	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007971	putative dithiobiotin synthetase; Provisional; Region: PRK12374
550537007972	AAA domain; Region: AAA_26; pfam13500
550537007973	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase, score 4e-28
550537007974	PS00017 ATP/GTP-binding site motif A (P-loop).
550537007975	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
550537007976	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
550537007977	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537007978	nucleotide binding site [chemical binding]; other site
550537007979	HMMPfam hit to PF00480, ROK, score 4.4e-36
550537007980	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
550537007981	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537007982	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
550537007983	dimerization interface [polypeptide binding]; other site
550537007984	substrate binding pocket [chemical binding]; other site
550537007985	HMMPfam hit to PF03466, LysR, substrate-binding, score 3e-51
550537007986	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 7.1e-20
550537007987	PS00044 Bacterial regulatory proteins, lysR family signature.
550537007988	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
550537007989	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537007990	putative substrate translocation pore; other site
550537007991	12 probable transmembrane helices predicted for SEN1564 by TMHMM2.0 at aa 37-59, 74-95, 102-124, 128-150, 157-179, 189-211, 240-262, 272-291, 304-323, 328-350, 363-385 and 389-411
550537007992	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.4e-43
550537007993	PS00216 Sugar transport proteins signature 1.
550537007994	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537007995	HMMPfam hit to PF06392, Acid shock, score 0.00032
550537007996	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
550537007997	HMMPfam hit to PF00089, Peptidase S1 and S6, chymotrypsin/Hap, score 2.3e-05
550537007998	PS00134 Serine proteases, trypsin family, histidine active site.
550537007999	PS00135 Serine proteases, trypsin family, serine active site.
550537008000	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
550537008001	4 probable transmembrane helices predicted for SEN1566 by TMHMM2.0 at aa 10-29, 36-53, 63-85 and 92-106
550537008002	HMMPfam hit to PF00893, Small multidrug resistance protein, score 5.1e-42
550537008003	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
550537008004	4 probable transmembrane helices predicted for SEN1567 by TMHMM2.0 at aa 2-19, 29-51, 56-78 and 82-101
550537008005	HMMPfam hit to PF00893, Small multidrug resistance protein, score 5.9e-34
550537008006	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
550537008007	Domain of unknown function DUF20; Region: UPF0118; pfam01594
550537008008	8 probable transmembrane helices predicted for SEN1568 by TMHMM2.0 at aa 5-24, 29-51, 63-85, 144-166, 196-218, 222-244, 257-279 and 299-321
550537008009	HMMPfam hit to PF01594, Protein of unknown function UPF0118, score 1.2e-83
550537008010	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
550537008011	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
550537008012	HMMPfam hit to PF02233, NAD(P) transhydrogenase, beta subunit, score 0
550537008013	9 probable transmembrane helices predicted for SEN1569 by TMHMM2.0 at aa 5-24, 33-50, 55-72, 85-107, 122-144, 164-181, 185-207, 214-236 and 240-259
550537008014	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
550537008015	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
550537008016	ligand binding site [chemical binding]; other site
550537008017	homodimer interface [polypeptide binding]; other site
550537008018	NAD(P) binding site [chemical binding]; other site
550537008019	trimer interface B [polypeptide binding]; other site
550537008020	trimer interface A [polypeptide binding]; other site
550537008021	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
550537008022	5 probable transmembrane helices predicted for SEN1570 by TMHMM2.0 at aa 169-191, 402-419, 423-445, 452-471 and 476-498
550537008023	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008024	HMMPfam hit to PF01262, Alanine dehydrogenase/PNT, C-terminal, score 1.7e-89
550537008025	PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2.
550537008026	HMMPfam hit to PF05222, Alanine dehydrogenase/PNT, N-terminal, score 1.7e-75
550537008027	PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1.
550537008028	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537008029	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537008030	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537008031	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 7.2e-11
550537008032	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
550537008033	Spore germination protein; Region: Spore_permease; cl17796
550537008034	13 probable transmembrane helices predicted for SEN1572 by TMHMM2.0 at aa 5-27, 37-59, 90-112, 127-149, 156-178, 205-222, 235-257, 277-299, 332-351, 356-378, 385-403, 408-427 and 440-459
550537008035	HMMPfam hit to PF00324, Amino acid permease-associated region, score 0.00031
550537008036	GlpM protein; Region: GlpM; pfam06942
550537008037	HMMPfam hit to PF06942, GlpM, score 8.7e-78
550537008038	2 probable transmembrane helices predicted for SEN1573 by TMHMM2.0 at aa 13-35 and 40-62
550537008039	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
550537008040	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537008041	active site
550537008042	phosphorylation site [posttranslational modification]
550537008043	intermolecular recognition site; other site
550537008044	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537008045	DNA binding site [nucleotide binding]
550537008046	HMMPfam hit to PF00072, Response regulator receiver, score 8.9e-21
550537008047	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 1.3e-17
550537008048	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537008049	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
550537008050	trimer interface [polypeptide binding]; other site
550537008051	eyelet of channel; other site
550537008052	1 probable transmembrane helix predicted for SEN1575 by TMHMM2.0 at aa 5-22
550537008053	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
550537008054	HMMPfam hit to PF00267, Porin, Gram-negative type, score 1.9e-220
550537008055	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
550537008056	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
550537008057	active site
550537008058	HMMPfam hit to PF07969, Amidohydrolase 3, score 1.2e-117
550537008059	sensor protein RstB; Provisional; Region: PRK10604
550537008060	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537008061	dimerization interface [polypeptide binding]; other site
550537008062	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537008063	dimer interface [polypeptide binding]; other site
550537008064	phosphorylation site [posttranslational modification]
550537008065	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537008066	ATP binding site [chemical binding]; other site
550537008067	Mg2+ binding site [ion binding]; other site
550537008068	G-X-G motif; other site
550537008069	2 probable transmembrane helices predicted for SEN1577 by TMHMM2.0 at aa 5-27 and 139-156
550537008070	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 2.7e-08
550537008071	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.1e-11
550537008072	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 8.5e-36
550537008073	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
550537008074	HMMPfam hit to PF05472, DNA replication terminus site-binding protein, score 7.9e-226
550537008075	fumarate hydratase; Reviewed; Region: fumC; PRK00485
550537008076	Class II fumarases; Region: Fumarase_classII; cd01362
550537008077	active site
550537008078	tetramer interface [polypeptide binding]; other site
550537008079	HMMPfam hit to PF00206, Fumarate lyase, score 1.5e-196
550537008080	PS00163 Fumarate lyases signature.
550537008081	fumarate hydratase; Provisional; Region: PRK15389
550537008082	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
550537008083	Fumarase C-terminus; Region: Fumerase_C; pfam05683
550537008084	HMMPfam hit to PF05683, Fe-S type hydro-lyases tartrate/fumarate beta region, score 5.6e-118
550537008085	PS00163 Fumarate lyases signature.
550537008086	HMMPfam hit to PF05681, Fe-S type hydro-lyases tartrate/fumarate alpha region, score 5e-141
550537008087	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008088	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
550537008089	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
550537008090	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
550537008091	HMMPfam hit to PF01238, Mannose-6-phosphate isomerase, type I, score 6.8e-186
550537008092	PS00965 Phosphomannose isomerase type I signature 1.
550537008093	PS00966 Phosphomannose isomerase type I signature 2.
550537008094	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
550537008095	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
550537008096	HMMPfam hit to PF06097, Protein of unknown function DUF945, bacterial, score 6.1e-286
550537008097	1 probable transmembrane helix predicted for SEN1583 by TMHMM2.0 at aa 5-24
550537008098	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008099	the sequence has been checked and is believed to be correct
550537008100	HMMPfam hit to PF00367, Phosphotransferase system, EIIB, score 3.2e-07
550537008101	the sequence has been checked and is believed to be correct
550537008102	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
550537008103	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
550537008104	active site
550537008105	purine riboside binding site [chemical binding]; other site
550537008106	HMMPfam hit to PF00962, Adenosine/AMP deaminase, score 2.1e-130
550537008107	PS00485 Adenosine and AMP deaminase signature.
550537008108	putative oxidoreductase; Provisional; Region: PRK11579
550537008109	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
550537008110	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
550537008111	HMMPfam hit to PF02894, Oxidoreductase, C-terminal, score 4.3e-25
550537008112	HMMPfam hit to PF01408, Oxidoreductase, N-terminal, score 4e-44
550537008113	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
550537008114	HMMPfam hit to PF05321, Haemolysin expression modulating, score 1.8e-38
550537008115	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
550537008116	4 probable transmembrane helices predicted for SEN1587 by TMHMM2.0 at aa 13-35, 55-77, 90-109 and 114-133
550537008117	electron transport complex protein RsxA; Provisional; Region: PRK05151
550537008118	HMMPfam hit to PF02508, RnfA-Nqr electron transport subunit, score 2e-115
550537008119	6 probable transmembrane helices predicted for SEN1588 by TMHMM2.0 at aa 5-27, 42-64, 69-88, 103-125, 132-154 and 169-191
550537008120	electron transport complex protein RnfB; Provisional; Region: PRK05113
550537008121	Putative Fe-S cluster; Region: FeS; cl17515
550537008122	4Fe-4S binding domain; Region: Fer4; pfam00037
550537008123	1 probable transmembrane helix predicted for SEN1589 by TMHMM2.0 at aa 4-26
550537008124	HMMPfam hit to PF04060,  Fe-S cluster, score 8.8e-14
550537008125	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 1.4e-07
550537008126	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537008127	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 1.1e-05
550537008128	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537008129	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
550537008130	SLBB domain; Region: SLBB; pfam10531
550537008131	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
550537008132	HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit, score 1.9e-100
550537008133	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.00077
550537008134	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537008135	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.00025
550537008136	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537008137	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
550537008138	HMMPfam hit to PF03116, NQR2 and RnfD, score 2.9e-188
550537008139	10 probable transmembrane helices predicted for SEN1591 by TMHMM2.0 at aa 20-39, 43-62, 69-91, 95-117, 124-146, 214-236, 243-262, 272-294, 301-318 and 323-342
550537008140	electron transport complex protein RnfG; Validated; Region: PRK01908
550537008141	HMMPfam hit to PF04205, FMN-binding, score 1.9e-27
550537008142	electron transport complex RsxE subunit; Provisional; Region: PRK12405
550537008143	HMMPfam hit to PF02508, RnfA-Nqr electron transport subunit, score 3e-117
550537008144	5 probable transmembrane helices predicted for SEN1593 by TMHMM2.0 at aa 34-56, 69-87, 91-113, 126-148 and 183-205
550537008145	endonuclease III; Provisional; Region: PRK10702
550537008146	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
550537008147	minor groove reading motif; other site
550537008148	helix-hairpin-helix signature motif; other site
550537008149	substrate binding pocket [chemical binding]; other site
550537008150	active site
550537008151	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
550537008152	HMMPfam hit to PF00730, HhH-GPD, score 1.5e-19
550537008153	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 4.3e-07
550537008154	PS01155 Endonuclease III family signature.
550537008155	PS00764 Endonuclease III iron-sulfur binding region signature.
550537008156	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
550537008157	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537008158	putative substrate translocation pore; other site
550537008159	POT family; Region: PTR2; pfam00854
550537008160	14 probable transmembrane helices predicted for SEN1595 by TMHMM2.0 at aa 22-44, 59-81, 90-107, 112-129, 150-172, 177-199, 220-239, 244-261, 274-296, 323-340, 353-371, 386-408, 415-437 and 457-479
550537008161	PS01022 PTR2 family proton/oligopeptide symporters signature 1.
550537008162	HMMPfam hit to PF00854, TGF-beta receptor, type I/II extracellular region, score 2.7e-106
550537008163	PS00778 Histidine acid phosphatases active site signature.
550537008164	PS01023 PTR2 family proton/oligopeptide symporters signature 2.
550537008165	glutathionine S-transferase; Provisional; Region: PRK10542
550537008166	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
550537008167	C-terminal domain interface [polypeptide binding]; other site
550537008168	GSH binding site (G-site) [chemical binding]; other site
550537008169	dimer interface [polypeptide binding]; other site
550537008170	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
550537008171	dimer interface [polypeptide binding]; other site
550537008172	N-terminal domain interface [polypeptide binding]; other site
550537008173	substrate binding pocket (H-site) [chemical binding]; other site
550537008174	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 9.4e-09
550537008175	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 2.8e-19
550537008176	pyridoxamine kinase; Validated; Region: PRK05756
550537008177	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
550537008178	dimer interface [polypeptide binding]; other site
550537008179	pyridoxal binding site [chemical binding]; other site
550537008180	ATP binding site [chemical binding]; other site
550537008181	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 2.4e-06
550537008182	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
550537008183	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
550537008184	active site
550537008185	HIGH motif; other site
550537008186	dimer interface [polypeptide binding]; other site
550537008187	KMSKS motif; other site
550537008188	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537008189	RNA binding surface [nucleotide binding]; other site
550537008190	HMMPfam hit to PF01479, RNA-binding S4, score 9.1e-05
550537008191	HMMPfam hit to PF00579, Aminoacyl-tRNA synthetase, class Ib, score 2e-136
550537008192	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537008193	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
550537008194	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
550537008195	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
550537008196	HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core, score 9.5e-32
550537008197	lysozyme inhibitor; Provisional; Region: PRK11372
550537008198	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
550537008199	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008200	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
550537008201	HMMPfam hit to PF03702, Protein of unknown function UPF0075, score 5.5e-244
550537008202	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
550537008203	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008204	HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 4.5e-10
550537008205	transcriptional regulator SlyA; Provisional; Region: PRK03573
550537008206	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
550537008207	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 6e-24
550537008208	PS01117 Bacterial regulatory proteins, marR family signature.
550537008209	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
550537008210	HMMPfam hit to PF07869, Protein of unknown function DUF1656, score 2.2e-26
550537008211	2 probable transmembrane helices predicted for SEN1604 by TMHMM2.0 at aa 18-40 and 53-75
550537008212	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
550537008213	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537008214	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537008215	1 probable transmembrane helix predicted for SEN1605 by TMHMM2.0 at aa 20-42
550537008216	HMMPfam hit to PF00529, Secretion protein HlyD, score 6.7e-48
550537008217	Fusaric acid resistance protein family; Region: FUSC; pfam04632
550537008218	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
550537008219	12 probable transmembrane helices predicted for SEN1606 by TMHMM2.0 at aa 23-41, 46-65, 72-90, 94-113, 120-142, 157-179, 362-381, 385-404, 411-433, 438-455, 462-481 and 496-515
550537008220	PS00435 Peroxidases proximal heme-ligand signature.
550537008221	HMMPfam hit to PF04632, Fusaric acid resistance protein conserved region, score 2.1e-45
550537008222	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008223	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
550537008224	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
550537008225	E-class dimer interface [polypeptide binding]; other site
550537008226	P-class dimer interface [polypeptide binding]; other site
550537008227	active site
550537008228	Cu2+ binding site [ion binding]; other site
550537008229	Zn2+ binding site [ion binding]; other site
550537008230	HMMPfam hit to PF00080, Superoxide dismutase, copper/zinc binding, score 3.1e-28
550537008231	PS00332 Copper/Zinc superoxide dismutase signature 2.
550537008232	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008233	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537008234	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537008235	active site
550537008236	catalytic tetrad [active]
550537008237	HMMPfam hit to PF00248, Aldo/keto reductase, score 4.3e-74
550537008238	Predicted Fe-S protein [General function prediction only]; Region: COG3313
550537008239	HMMPfam hit to PF06945, Protein of unknown function DUF1289, score 6e-25
550537008240	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
550537008241	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537008242	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 3.3e-12
550537008243	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008244	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
550537008245	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
550537008246	FMN binding site [chemical binding]; other site
550537008247	active site
550537008248	substrate binding site [chemical binding]; other site
550537008249	catalytic residue [active]
550537008250	HMMPfam hit to PF00724, NADH:flavin oxidoreductase/NADH oxidase, N-terminal, score 4.3e-108
550537008251	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537008252	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
550537008253	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
550537008254	dimer interface [polypeptide binding]; other site
550537008255	active site
550537008256	metal binding site [ion binding]; metal-binding site
550537008257	glutathione binding site [chemical binding]; other site
550537008258	HMMPfam hit to PF00903, Glyoxalase/bleomycin resistance protein/dioxygenase, score 8.4e-42
550537008259	PS00934 Glyoxalase I signature 1.
550537008260	PS00935 Glyoxalase I signature 2.
550537008261	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
550537008262	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
550537008263	dimer interface [polypeptide binding]; other site
550537008264	catalytic site [active]
550537008265	putative active site [active]
550537008266	putative substrate binding site [chemical binding]; other site
550537008267	HMMPfam hit to PF00929, Exonuclease, RNase T and DNA polymerase III, score 2.4e-35
550537008268	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
550537008269	putative GSH binding site [chemical binding]; other site
550537008270	catalytic residues [active]
550537008271	HMMPfam hit to PF00462, Glutaredoxin, score 9.6e-28
550537008272	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008273	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
550537008274	NlpC/P60 family; Region: NLPC_P60; pfam00877
550537008275	HMMPfam hit to PF00877, NLP/P60, score 2.1e-56
550537008276	superoxide dismutase; Provisional; Region: PRK10543
550537008277	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
550537008278	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
550537008279	HMMPfam hit to PF00081, Manganese and iron superoxide dismutase, score 3e-53
550537008280	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008281	HMMPfam hit to PF02777, Manganese and iron superoxide dismutase, score 4.6e-83
550537008282	PS00088 Manganese and iron superoxide dismutases signature.
550537008283	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
550537008284	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537008285	DNA binding site [nucleotide binding]
550537008286	domain linker motif; other site
550537008287	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
550537008288	dimerization interface [polypeptide binding]; other site
550537008289	ligand binding site [chemical binding]; other site
550537008290	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 1.6e-12
550537008291	PS00356 Bacterial regulatory proteins, lacI family signature.
550537008292	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 1.2e-25
550537008293	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
550537008294	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537008295	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537008296	dimerization interface [polypeptide binding]; other site
550537008297	HMMPfam hit to PF03466, LysR, substrate-binding, score 4.5e-28
550537008298	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 5.2e-19
550537008299	PS00044 Bacterial regulatory proteins, lysR family signature.
550537008300	putative transporter; Provisional; Region: PRK11043
550537008301	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537008302	putative substrate translocation pore; other site
550537008303	11 probable transmembrane helices predicted for SEN1619 by TMHMM2.0 at aa 7-29, 39-61, 73-92, 97-119, 132-154, 159-178, 208-230, 235-257, 270-292, 296-318 and 339-361
550537008304	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.6e-53
550537008305	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008306	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
550537008307	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537008308	S-adenosylmethionine binding site [chemical binding]; other site
550537008309	HMMPfam hit to PF02353, Cyclopropane-fatty-acyl-phospholipid synthase, score 2.4e-165
550537008310	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
550537008311	Lumazine binding domain; Region: Lum_binding; pfam00677
550537008312	Lumazine binding domain; Region: Lum_binding; pfam00677
550537008313	HMMPfam hit to PF00677, Lumazine-binding protein, score 4.8e-44
550537008314	HMMPfam hit to PF00677, Lumazine-binding protein, score 1e-44
550537008315	PS00693 Riboflavin synthase alpha chain family signature.
550537008316	multidrug efflux protein; Reviewed; Region: PRK01766
550537008317	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
550537008318	cation binding site [ion binding]; other site
550537008319	12 probable transmembrane helices predicted for SEN1622 by TMHMM2.0 at aa 12-34, 44-66, 91-113, 128-147, 160-180, 190-212, 241-263, 278-300, 313-335, 350-367, 387-409 and 419-438
550537008320	HMMPfam hit to PF01554, Multi antimicrobial extrusion protein MatE, score 9.9e-49
550537008321	HMMPfam hit to PF01554, Multi antimicrobial extrusion protein MatE, score 1.6e-47
550537008322	Salmonella Pathogenicity Island 2: SPI-2.
550537008323	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
550537008324	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
550537008325	HMMPfam hit to PF01312, Type III secretion exporter, score 6.7e-189
550537008326	4 probable transmembrane helices predicted for SEN1623 by TMHMM2.0 at aa 21-43, 86-108, 146-168 and 178-200
550537008327	type III secretion system protein SsaT; Provisional; Region: PRK15349
550537008328	HMMPfam hit to PF01311, Type III secretion system inner membrane R protein, score 2.6e-107
550537008329	6 probable transmembrane helices predicted for SEN1624 by TMHMM2.0 at aa 7-29, 34-56, 68-90, 129-151, 183-205 and 215-237
550537008330	type III secretion system protein SsaS; Provisional; Region: PRK15350
550537008331	HMMPfam hit to PF01313, Bacterial export protein FliQ, family 3, score 2.3e-39
550537008332	2 probable transmembrane helices predicted for SEN1625 by TMHMM2.0 at aa 13-35 and 55-77
550537008333	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
550537008334	4 probable transmembrane helices predicted for SEN1626 by TMHMM2.0 at aa 10-31, 52-74, 154-176 and 189-211
550537008335	HMMPfam hit to PF00813, Type III secretion system inner membrane P protein, score 1.3e-118
550537008336	PS01061 Flagella transport protein fliP family signature 2.
550537008337	PS01060 Flagella transport protein fliP family signature 1.
550537008338	type III secretion system protein SsaQ; Validated; Region: PRK08035
550537008339	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
550537008340	HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) protein, score 3.6e-29
550537008341	type III secretion system protein SsaP; Provisional; Region: PRK15351
550537008342	type III secretion system protein SsaO; Provisional; Region: PRK15352
550537008343	type III secretion system ATPase SsaN; Validated; Region: PRK07594
550537008344	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
550537008345	Walker A motif; other site
550537008346	ATP binding site [chemical binding]; other site
550537008347	Walker B motif; other site
550537008348	HMMPfam hit to PF00006, ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding, score 1.2e-117
550537008349	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
550537008350	FHIPEP family; Region: FHIPEP; pfam00771
550537008351	HMMPfam hit to PF00771, Bacterial type III secretion FHIPEP, score 0
550537008352	6 probable transmembrane helices predicted for SEN1631 by TMHMM2.0 at aa 24-41, 48-67, 115-137, 206-228, 248-270 and 291-313
550537008353	PS00994 Bacterial export FHIPEP family signature.
550537008354	type III secretion system protein SsaM; Provisional; Region: PRK15353
550537008355	type III secretion system protein SsaL; Provisional; Region: PRK15345
550537008356	HrpJ-like domain; Region: HrpJ; pfam07201
550537008357	TyeA; Region: TyeA; cl07611
550537008358	HMMPfam hit to PF07018, SepL/SsaL, score 2.5e-246
550537008359	type III secretion system protein SsaK; Provisional; Region: PRK15354
550537008360	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
550537008361	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
550537008362	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
550537008363	1 probable transmembrane helix predicted for SEN1636 by TMHMM2.0 at aa 223-245
550537008364	HMMPfam hit to PF01514, Secretory protein YscJ/FliF, score 8.3e-91
550537008365	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008366	type III secretion system protein SsaI; Provisional; Region: PRK15355
550537008367	type III secretion system protein SsaH; Provisional; Region: PRK15356
550537008368	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
550537008369	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
550537008370	2 probable transmembrane helices predicted for SEN1640 by TMHMM2.0 at aa 65-87 and 97-116
550537008371	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
550537008372	2 probable transmembrane helices predicted for SEN1641 by TMHMM2.0 at aa 64-86 and 90-112
550537008373	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
550537008374	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
550537008375	TPR motif; other site
550537008376	binding surface
550537008377	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
550537008378	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
550537008379	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
550537008380	HMMPfam hit to PF04888, Secretion system effector C (SseC) like protein, score 4.1e-289
550537008381	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008382	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
550537008383	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 0.00011
550537008384	HMMPfam hit to PF07720, Tetratricopeptide TPR-3, score 0.0016
550537008385	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
550537008386	HMMPfam hit to PF03433, EspA-like secreted protein, score 6.5e-136
550537008387	type III secretion system chaperone SseA; Provisional; Region: PRK15365
550537008388	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
550537008389	type III secretion system protein SsaD; Provisional; Region: PRK15367
550537008390	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
550537008391	1 probable transmembrane helix predicted for SEN1650 by TMHMM2.0 at aa 117-139
550537008392	outer membrane secretin SsaC; Provisional; Region: PRK15346
550537008393	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
550537008394	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
550537008395	HMMPfam hit to PF00263, Bacterial type II and III secretion system protein, score 3.8e-72
550537008396	PS00875 Bacterial type II secretion system protein D signature.
550537008397	HMMPfam hit to PF03958, NolW-like, score 7.1e-12
550537008398	HMMPfam hit to PF03958, NolW-like, score 2.2e-10
550537008399	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
550537008400	two component system sensor kinase SsrA; Provisional; Region: PRK15347
550537008401	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537008402	dimerization interface [polypeptide binding]; other site
550537008403	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537008404	dimer interface [polypeptide binding]; other site
550537008405	phosphorylation site [posttranslational modification]
550537008406	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537008407	ATP binding site [chemical binding]; other site
550537008408	Mg2+ binding site [ion binding]; other site
550537008409	G-X-G motif; other site
550537008410	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537008411	active site
550537008412	phosphorylation site [posttranslational modification]
550537008413	intermolecular recognition site; other site
550537008414	dimerization interface [polypeptide binding]; other site
550537008415	1 probable transmembrane helix predicted for SEN1653 by TMHMM2.0 at aa 20-42
550537008416	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 4.5e-12
550537008417	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 3.7e-22
550537008418	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2.2e-38
550537008419	HMMPfam hit to PF00072, Response regulator receiver, score 2.3e-22
550537008420	two component system sensor kinase SsrB; Provisional; Region: PRK15369
550537008421	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537008422	active site
550537008423	phosphorylation site [posttranslational modification]
550537008424	intermolecular recognition site; other site
550537008425	dimerization interface [polypeptide binding]; other site
550537008426	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537008427	DNA binding residues [nucleotide binding]
550537008428	dimerization interface [polypeptide binding]; other site
550537008429	HMMPfam hit to PF00072, Response regulator receiver, score 6.9e-31
550537008430	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 8.2e-18
550537008431	PS00622 Bacterial regulatory proteins, luxR family signature.
550537008432	transcriptional regulator MirA; Provisional; Region: PRK15043
550537008433	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
550537008434	DNA binding residues [nucleotide binding]
550537008435	HMMPfam hit to PF00376, Bacterial regulatory protein, MerR, score 6.9e-14
550537008436	PS00552 Bacterial regulatory proteins, merR family signature.
550537008437	Uncharacterized conserved protein [Function unknown]; Region: COG1683
550537008438	Uncharacterized conserved protein [Function unknown]; Region: COG3272
550537008439	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
550537008440	HMMPfam hit to PF04463, Protein of unknown function DUF523, score 1.3e-74
550537008441	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537008442	HMMPfam hit to PF08349, Protein of unknown function DUF1722, score 5.1e-68
550537008443	hypothetical protein; Provisional; Region: PRK10292
550537008444	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
550537008445	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537008446	active site
550537008447	phosphorylation site [posttranslational modification]
550537008448	intermolecular recognition site; other site
550537008449	dimerization interface [polypeptide binding]; other site
550537008450	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537008451	DNA binding residues [nucleotide binding]
550537008452	dimerization interface [polypeptide binding]; other site
550537008453	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1.2e-21
550537008454	PS00622 Bacterial regulatory proteins, luxR family signature.
550537008455	HMMPfam hit to PF00072, Response regulator receiver, score 2.1e-24
550537008456	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
550537008457	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
550537008458	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
550537008459	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537008460	dimer interface [polypeptide binding]; other site
550537008461	phosphorylation site [posttranslational modification]
550537008462	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537008463	ATP binding site [chemical binding]; other site
550537008464	Mg2+ binding site [ion binding]; other site
550537008465	G-X-G motif; other site
550537008466	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.9e-25
550537008467	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 5.4e-06
550537008468	2 probable transmembrane helices predicted for SEN1659 by TMHMM2.0 at aa 9-31 and 305-327
550537008469	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008470	tetrathionate reductase subunit B; Provisional; Region: PRK14993
550537008471	4Fe-4S binding domain; Region: Fer4; pfam00037
550537008472	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0072
550537008473	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 6e-07
550537008474	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537008475	tetrathionate reductase subunit C; Provisional; Region: PRK14992
550537008476	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
550537008477	HMMPfam hit to PF03916, Polysulphide reductase, NrfD, score 8.1e-100
550537008478	9 probable transmembrane helices predicted for SEN1661 by TMHMM2.0 at aa 23-45, 58-77, 92-114, 126-148, 163-185, 192-214, 237-254, 266-288 and 308-326
550537008479	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008480	tetrathionate reductase subunit A; Provisional; Region: PRK14991
550537008481	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
550537008482	putative [Fe4-S4] binding site [ion binding]; other site
550537008483	putative molybdopterin cofactor binding site [chemical binding]; other site
550537008484	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
550537008485	putative molybdopterin cofactor binding site; other site
550537008486	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 4.6e-06
550537008487	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 1.4e-05
550537008488	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 3.9e-10
550537008489	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537008490	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537008491	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537008492	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
550537008493	substrate binding site [chemical binding]; other site
550537008494	dimer interface [polypeptide binding]; other site
550537008495	ATP binding site [chemical binding]; other site
550537008496	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 2.8e-12
550537008497	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 3.5e-83
550537008498	PS00583 pfkB family of carbohydrate kinases signature 1.
550537008499	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
550537008500	HMMPfam hit to PF07090, Protein of unknown function DUF1355, score 1.7e-204
550537008501	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
550537008502	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
550537008503	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 5.5e-16
550537008504	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
550537008505	13 probable transmembrane helices predicted for SEN1666 by TMHMM2.0 at aa 10-32, 39-61, 71-93, 95-114, 119-138, 147-169, 184-206, 227-249, 273-295, 330-347, 357-379, 386-405 and 409-428
550537008506	HMMPfam hit to PF00324, Amino acid permease-associated region, score 7e-09
550537008507	pyruvate kinase; Provisional; Region: PRK09206
550537008508	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
550537008509	active site
550537008510	domain interfaces; other site
550537008511	HMMPfam hit to PF00224, Pyruvate kinase, barrel, score 4.5e-196
550537008512	PS00110 Pyruvate kinase active site signature.
550537008513	HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta, score 8.2e-31
550537008514	murein lipoprotein; Provisional; Region: PRK15396
550537008515	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008516	HMMPfam hit to PF04728, LPP motif, score 0.012
550537008517	HMMPfam hit to PF04728, LPP motif, score 0.013
550537008518	murein lipoprotein; Provisional; Region: PRK15396
550537008519	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008520	HMMPfam hit to PF04728, LPP motif, score 0.012
550537008521	L,D-transpeptidase; Provisional; Region: PRK10190
550537008522	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537008523	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
550537008524	HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 7.1e-62
550537008525	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 1.2e-08
550537008526	cysteine desufuration protein SufE; Provisional; Region: PRK09296
550537008527	HMMPfam hit to PF02657, Fe-S metabolism associated SufE, score 6.3e-64
550537008528	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
550537008529	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
550537008530	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537008531	catalytic residue [active]
550537008532	HMMPfam hit to PF00266, Aminotransferase, class V, score 1.5e-230
550537008533	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
550537008534	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
550537008535	FeS assembly protein SufD; Region: sufD; TIGR01981
550537008536	HMMPfam hit to PF01458, SUF system FeS cluster assembly, SufBD, score 1.4e-93
550537008537	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
550537008538	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
550537008539	Walker A/P-loop; other site
550537008540	ATP binding site [chemical binding]; other site
550537008541	Q-loop/lid; other site
550537008542	ABC transporter signature motif; other site
550537008543	Walker B; other site
550537008544	D-loop; other site
550537008545	H-loop/switch region; other site
550537008546	HMMPfam hit to PF00005, ABC transporter related, score 6.1e-32
550537008547	PS00211 ABC transporters family signature.
550537008548	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008549	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
550537008550	putative ABC transporter; Region: ycf24; CHL00085
550537008551	HMMPfam hit to PF01458, SUF system FeS cluster assembly, SufBD, score 4.6e-148
550537008552	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
550537008553	PS01152 Hypothetical hesB/yadR/yfhF family signature.
550537008554	HMMPfam hit to PF01521, HesB/YadR/YfhF, score 2e-35
550537008555	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
550537008556	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
550537008557	11 probable transmembrane helices predicted for SEN1677 by TMHMM2.0 at aa 4-19, 32-51, 66-88, 101-123, 170-192, 220-242, 252-274, 286-308, 336-353, 358-380 and 384-406
550537008558	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter, score 1.3e-58
550537008559	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008560	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
550537008561	CoenzymeA binding site [chemical binding]; other site
550537008562	subunit interaction site [polypeptide binding]; other site
550537008563	PHB binding site; other site
550537008564	HMMPfam hit to PF03061, Thioesterase superfamily, score 6.7e-19
550537008565	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
550537008566	FAD binding domain; Region: FAD_binding_4; pfam01565
550537008567	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
550537008568	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537008569	HMMPfam hit to PF02913, FAD linked oxidase, C-terminal, score 7.5e-75
550537008570	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537008571	HMMPfam hit to PF01565, FAD linked oxidase, N-terminal, score 9.2e-49
550537008572	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008573	putative inner membrane protein; Provisional; Region: PRK10983
550537008574	Domain of unknown function DUF20; Region: UPF0118; pfam01594
550537008575	8 probable transmembrane helices predicted for SEN1681 by TMHMM2.0 at aa 13-32, 36-53, 65-87, 159-181, 202-224, 237-259, 266-288 and 308-330
550537008576	HMMPfam hit to PF01594, Protein of unknown function UPF0118, score 2.2e-70
550537008577	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008578	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
550537008579	HMMPfam hit to PF08965, Protein of unknown function DUF1870, score 7.9e-95
550537008580	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537008581	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537008582	putative substrate translocation pore; other site
550537008583	12 probable transmembrane helices predicted for SEN1683 by TMHMM2.0 at aa 7-29, 39-61, 74-91, 95-112, 133-155, 159-181, 211-233, 248-270, 277-299, 303-325, 337-359 and 364-386
550537008584	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.1e-32
550537008585	PS00216 Sugar transport proteins signature 1.
550537008586	PS00043 Bacterial regulatory proteins, gntR family signature.
550537008587	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537008588	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537008589	putative substrate translocation pore; other site
550537008590	12 probable transmembrane helices predicted for SEN1684 by TMHMM2.0 at aa 12-34, 49-71, 78-97, 101-118, 138-160, 164-186, 212-234, 254-273, 280-302, 307-329, 350-372 and 376-395
550537008591	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4.1e-33
550537008592	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
550537008593	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
550537008594	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
550537008595	shikimate binding site; other site
550537008596	NAD(P) binding site [chemical binding]; other site
550537008597	HMMPfam hit to PF08501, Shikimate dehydrogenase substrate binding, N-terminal, score 5.6e-39
550537008598	HMMPfam hit to PF01488, Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase, score 6.7e-26
550537008599	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008600	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
550537008601	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
550537008602	active site
550537008603	catalytic residue [active]
550537008604	dimer interface [polypeptide binding]; other site
550537008605	HMMPfam hit to PF01487, Dehydroquinase class I, score 3.3e-111
550537008606	PS01028 Dehydroquinase class I active site.
550537008607	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
550537008608	Coenzyme A transferase; Region: CoA_trans; smart00882
550537008609	Coenzyme A transferase; Region: CoA_trans; cl17247
550537008610	HMMPfam hit to PF01144, Coenzyme A transferase, score 3.4e-66
550537008611	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
550537008612	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
550537008613	active site
550537008614	HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal, score 6.6e-18
550537008615	HMMPfam hit to PF02770, Acyl-CoA dehydrogenase/oxidase, central region, score 5.6e-14
550537008616	PS00072 Acyl-CoA dehydrogenases signature 1.
550537008617	HMMPfam hit to PF00441, Acyl-CoA oxidase/dehydrogenase, type 1, score 3.9e-57
550537008618	PS00073 Acyl-CoA dehydrogenases signature 2.
550537008619	Cupin domain; Region: Cupin_2; pfam07883
550537008620	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537008621	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537008622	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 5.2e-06
550537008623	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 9.1e-05
550537008624	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 1.3e-10
550537008625	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
550537008626	Ligand binding site [chemical binding]; other site
550537008627	Electron transfer flavoprotein domain; Region: ETF; pfam01012
550537008628	HMMPfam hit to PF01012, Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, score 6.7e-52
550537008629	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
550537008630	Electron transfer flavoprotein domain; Region: ETF; smart00893
550537008631	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
550537008632	HMMPfam hit to PF01012, Electron transfer flavoprotein, alpha/beta-subunit, N-terminal, score 3e-31
550537008633	HMMPfam hit to PF00766, Electron transfer flavoprotein, alpha subunit, C-terminal, score 4.4e-41
550537008634	PS00696 Electron transfer flavoprotein alpha-subunit signature.
550537008635	oxidoreductase; Provisional; Region: PRK10015
550537008636	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6e-14
550537008637	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
550537008638	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537008639	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
550537008640	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
550537008641	acyl-activating enzyme (AAE) consensus motif; other site
550537008642	putative AMP binding site [chemical binding]; other site
550537008643	putative active site [active]
550537008644	putative CoA binding site [chemical binding]; other site
550537008645	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 3.2e-124
550537008646	PS00455  AMP-binding domain signature.
550537008647	phosphoenolpyruvate synthase; Validated; Region: PRK06464
550537008648	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
550537008649	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
550537008650	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
550537008651	HMMPfam hit to PF02896, PEP-utilizing enzyme, score 3.1e-63
550537008652	PS00742 PEP-utilizing enzymes signature 2.
550537008653	HMMPfam hit to PF00391, PEP-utilising enzyme, mobile region, score 2.6e-42
550537008654	PS00370 PEP-utilizing enzymes phosphorylation site signature.
550537008655	HMMPfam hit to PF01326, Pyruvate phosphate dikinase, PEP/pyruvate-binding, score 1e-173
550537008656	PEP synthetase regulatory protein; Provisional; Region: PRK05339
550537008657	HMMPfam hit to PF03618, Protein of unknown function DUF299, score 2e-163
550537008658	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008659	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
550537008660	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
550537008661	HMMPfam hit to PF00793, DAHP synthetase I/KDSA, score 1e-172
550537008662	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
550537008663	Uncharacterized conserved protein [Function unknown]; Region: COG0397
550537008664	hypothetical protein; Validated; Region: PRK00029
550537008665	HMMPfam hit to PF02696, Protein of unknown function UPF0061, score 5.7e-248
550537008666	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
550537008667	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008668	NlpC/P60 family; Region: NLPC_P60; pfam00877
550537008669	HMMPfam hit to PF00877, NLP/P60, score 2.5e-48
550537008670	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008671	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
550537008672	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
550537008673	Walker A/P-loop; other site
550537008674	ATP binding site [chemical binding]; other site
550537008675	Q-loop/lid; other site
550537008676	ABC transporter signature motif; other site
550537008677	Walker B; other site
550537008678	D-loop; other site
550537008679	H-loop/switch region; other site
550537008680	HMMPfam hit to PF00005, ABC transporter related, score 1.7e-38
550537008681	PS00211 ABC transporters family signature.
550537008682	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008683	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
550537008684	catalytic residues [active]
550537008685	dimer interface [polypeptide binding]; other site
550537008686	HMMPfam hit to PF00255, Glutathione peroxidase, score 4.3e-67
550537008687	PS00763 Glutathione peroxidases signature 2.
550537008688	PS00460 Glutathione peroxidases selenocysteine active site.
550537008689	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
550537008690	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537008691	ABC-ATPase subunit  interface; other site
550537008692	dimer interface [polypeptide binding]; other site
550537008693	putative PBP binding regions; other site
550537008694	HMMPfam hit to PF01032, Bacterial transport system permease protein, score 1.3e-133
550537008695	9 probable transmembrane helices predicted for SEN1704 by TMHMM2.0 at aa 17-39, 59-81, 88-107, 111-133, 146-168, 188-205, 242-264, 274-296 and 303-322
550537008696	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
550537008697	IHF dimer interface [polypeptide binding]; other site
550537008698	IHF - DNA interface [nucleotide binding]; other site
550537008699	HMMPfam hit to PF00216, Histone-like bacterial DNA-binding protein, score 4.7e-47
550537008700	PS00045 Bacterial histone-like DNA-binding proteins signature.
550537008701	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
550537008702	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
550537008703	putative tRNA-binding site [nucleotide binding]; other site
550537008704	B3/4 domain; Region: B3_4; pfam03483
550537008705	tRNA synthetase B5 domain; Region: B5; smart00874
550537008706	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
550537008707	dimer interface [polypeptide binding]; other site
550537008708	motif 1; other site
550537008709	motif 3; other site
550537008710	motif 2; other site
550537008711	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
550537008712	HMMPfam hit to PF03147, Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding, score 1.7e-47
550537008713	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537008714	HMMPfam hit to PF03484, tRNA synthetase, B5, score 4.1e-31
550537008715	HMMPfam hit to PF03483, B3/4, score 1.3e-112
550537008716	HMMPfam hit to PF01588, tRNA-binding region, score 4.7e-45
550537008717	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
550537008718	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
550537008719	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
550537008720	dimer interface [polypeptide binding]; other site
550537008721	motif 1; other site
550537008722	active site
550537008723	motif 2; other site
550537008724	motif 3; other site
550537008725	HMMPfam hit to PF01409, Phenylalanyl-tRNA synthetase, class IIc, score 3.4e-169
550537008726	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537008727	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537008728	HMMPfam hit to PF02912, Phenylalanyl-tRNA synthetase, class II, N-terminal, score 1.2e-39
550537008729	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
550537008730	23S rRNA binding site [nucleotide binding]; other site
550537008731	L21 binding site [polypeptide binding]; other site
550537008732	L13 binding site [polypeptide binding]; other site
550537008733	HMMPfam hit to PF00453, Ribosomal protein L20, score 2.9e-69
550537008734	PS00937 Ribosomal protein L20 signature.
550537008735	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
550537008736	HMMPfam hit to PF01632, Ribosomal protein L35, score 1.2e-32
550537008737	PS00936 Ribosomal protein L35 signature.
550537008738	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
550537008739	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
550537008740	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
550537008741	HMMPfam hit to PF00707, Initiation factor 3, score 2.8e-55
550537008742	HMMPfam hit to PF05198, Initiation factor 3, score 1.5e-19
550537008743	PS00938 Initiation factor 3 signature.
550537008744	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
550537008745	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
550537008746	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
550537008747	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
550537008748	active site
550537008749	dimer interface [polypeptide binding]; other site
550537008750	motif 1; other site
550537008751	motif 2; other site
550537008752	motif 3; other site
550537008753	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
550537008754	anticodon binding site; other site
550537008755	HMMPfam hit to PF03129, Anticodon-binding, score 6.1e-33
550537008756	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537008757	HMMPfam hit to PF00587, Aminoacyl-tRNA synthetase, class II (G, H, P and S), score 8.1e-66
550537008758	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537008759	HMMPfam hit to PF07973, Threonyl/alanyl tRNA synthetase, SAD, score 4.1e-24
550537008760	HMMPfam hit to PF02824, TGS, score 5.1e-16
550537008761	10 probable transmembrane helices predicted for SEN1712 by TMHMM2.0 at aa 2-24, 28-50, 63-85, 100-120, 141-163, 173-204, 211-233, 321-343, 355-377 and 381-403
550537008762	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
550537008763	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
550537008764	active site
550537008765	substrate binding site [chemical binding]; other site
550537008766	Mg2+ binding site [ion binding]; other site
550537008767	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 6.5e-57
550537008768	PS01070 DNA/RNA non-specific endonucleases active site.
550537008769	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
550537008770	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
550537008771	HMMPfam hit to PF04338, Protein of unknown function DUF481, score 8.8e-116
550537008772	1 probable transmembrane helix predicted for SEN1716 by TMHMM2.0 at aa 7-24
550537008773	6-phosphofructokinase 2; Provisional; Region: PRK10294
550537008774	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
550537008775	putative substrate binding site [chemical binding]; other site
550537008776	putative ATP binding site [chemical binding]; other site
550537008777	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 9.7e-74
550537008778	PS00583 pfkB family of carbohydrate kinases signature 1.
550537008779	PS00584 pfkB family of carbohydrate kinases signature 2.
550537008780	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
550537008781	Phosphotransferase enzyme family; Region: APH; pfam01636
550537008782	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
550537008783	active site
550537008784	ATP binding site [chemical binding]; other site
550537008785	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
550537008786	HMMPfam hit to PF03881, Fructosamine kinase, score 2.2e-215
550537008787	YniB-like protein; Region: YniB; pfam14002
550537008788	3 probable transmembrane helices predicted for SEN1720 by TMHMM2.0 at aa 16-38, 79-101 and 150-172
550537008789	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
550537008790	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
550537008791	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537008792	motif II; other site
550537008793	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 5.1e-32
550537008794	inner membrane protein; Provisional; Region: PRK11648
550537008795	HMMPfam hit to PF04307, Protein of unknown function DUF457, transmembrane, score 1.1e-40
550537008796	2 probable transmembrane helices predicted for SEN1722 by TMHMM2.0 at aa 72-94 and 109-131
550537008797	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
550537008798	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
550537008799	9 probable transmembrane helices predicted for SEN1723 by TMHMM2.0 at aa 5-22, 34-51, 71-93, 105-127, 180-202, 260-282, 340-362, 369-391 and 395-417
550537008800	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter, score 2.5e-111
550537008801	cell division modulator; Provisional; Region: PRK10113
550537008802	hydroperoxidase II; Provisional; Region: katE; PRK11249
550537008803	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
550537008804	tetramer interface [polypeptide binding]; other site
550537008805	heme binding pocket [chemical binding]; other site
550537008806	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
550537008807	domain interactions; other site
550537008808	HMMPfam hit to PF00199, Catalase, N-terminal, score 4e-282
550537008809	PS00438 Catalase proximal active site signature.
550537008810	PS00437 Catalase proximal heme-ligand signature.
550537008811	HMMPfam hit to PF06628, Catalase-related, score 4.1e-32
550537008812	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
550537008813	putative active site [active]
550537008814	YdjC motif; other site
550537008815	Mg binding site [ion binding]; other site
550537008816	putative homodimer interface [polypeptide binding]; other site
550537008817	HMMPfam hit to PF04794, YdjC-like protein, score 5.3e-109
550537008818	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
550537008819	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
550537008820	NAD binding site [chemical binding]; other site
550537008821	sugar binding site [chemical binding]; other site
550537008822	divalent metal binding site [ion binding]; other site
550537008823	tetramer (dimer of dimers) interface [polypeptide binding]; other site
550537008824	dimer interface [polypeptide binding]; other site
550537008825	HMMPfam hit to PF02056, Glycoside hydrolase, family 4, score 2.2e-223
550537008826	PS01324 Glycosyl hydrolases family 4 signature.
550537008827	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
550537008828	Cupin domain; Region: Cupin_2; pfam07883
550537008829	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537008830	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 7.1e-13
550537008831	PS00041 Bacterial regulatory proteins, araC family signature.
550537008832	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 0.00018
550537008833	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
550537008834	methionine cluster; other site
550537008835	active site
550537008836	phosphorylation site [posttranslational modification]
550537008837	metal binding site [ion binding]; metal-binding site
550537008838	HMMPfam hit to PF02255, Phosphotransferase system, lactose/cellobiose-specific IIA subunit, score 2e-49
550537008839	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
550537008840	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
550537008841	10 probable transmembrane helices predicted for SEN1730 by TMHMM2.0 at aa 31-53, 85-107, 114-133, 143-165, 186-208, 232-254, 302-321, 341-363, 370-392 and 407-429
550537008842	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 3.2e-61
550537008843	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008844	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
550537008845	active site
550537008846	P-loop; other site
550537008847	phosphorylation site [posttranslational modification]
550537008848	HMMPfam hit to PF02302, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, score 4.2e-25
550537008849	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
550537008850	HMMPfam hit to PF04355, SmpA/OmlA, score 2.6e-22
550537008851	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008852	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
550537008853	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
550537008854	homodimer interface [polypeptide binding]; other site
550537008855	NAD binding pocket [chemical binding]; other site
550537008856	ATP binding pocket [chemical binding]; other site
550537008857	Mg binding site [ion binding]; other site
550537008858	active-site loop [active]
550537008859	HMMPfam hit to PF02540, NAD+ synthase, score 1.2e-126
550537008860	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
550537008861	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
550537008862	GIY-YIG motif/motif A; other site
550537008863	active site
550537008864	catalytic site [active]
550537008865	putative DNA binding site [nucleotide binding]; other site
550537008866	metal binding site [ion binding]; metal-binding site
550537008867	HMMPfam hit to PF01541, Excinuclease ABC, C subunit, N-terminal, score 2.1e-16
550537008868	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
550537008869	dimer interface [polypeptide binding]; other site
550537008870	HMMPfam hit to PF07813, Region of unknown function, Spy-related, score 0.0033
550537008871	HMMPfam hit to PF07813, Region of unknown function, Spy-related, score 1.3e-05
550537008872	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
550537008873	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
550537008874	putative active site [active]
550537008875	Zn binding site [ion binding]; other site
550537008876	HMMPfam hit to PF04952, Succinylglutamate desuccinylase/aspartoacylase, score 1.1e-99
550537008877	succinylarginine dihydrolase; Provisional; Region: PRK13281
550537008878	HMMPfam hit to PF04996, Succinylarginine dihydrolase, score 0
550537008879	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
550537008880	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
550537008881	NAD(P) binding site [chemical binding]; other site
550537008882	catalytic residues [active]
550537008883	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 3.4e-119
550537008884	PS00070 Aldehyde dehydrogenases cysteine active site.
550537008885	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537008886	arginine succinyltransferase; Provisional; Region: PRK10456
550537008887	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
550537008888	HMMPfam hit to PF04958, Arginine N-succinyltransferase beta subunit, score 7.5e-238
550537008889	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
550537008890	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
550537008891	inhibitor-cofactor binding pocket; inhibition site
550537008892	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537008893	catalytic residue [active]
550537008894	HMMPfam hit to PF00202, Aminotransferase class-III, score 1.7e-155
550537008895	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
550537008896	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
550537008897	putative catalytic site [active]
550537008898	putative phosphate binding site [ion binding]; other site
550537008899	active site
550537008900	metal binding site A [ion binding]; metal-binding site
550537008901	DNA binding site [nucleotide binding]
550537008902	putative AP binding site [nucleotide binding]; other site
550537008903	putative metal binding site B [ion binding]; other site
550537008904	HMMPfam hit to PF03372, Endonuclease/exonuclease/phosphatase, score 9.5e-52
550537008905	PS00726 AP endonucleases family 1 signature 1.
550537008906	PS00728 AP endonucleases family 1 signature 3.
550537008907	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
550537008908	active site
550537008909	8-oxo-dGMP binding site [chemical binding]; other site
550537008910	nudix motif; other site
550537008911	metal binding site [ion binding]; metal-binding site
550537008912	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 8.2e-34
550537008913	PS00893 mutT domain signature.
550537008914	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
550537008915	HMMPfam hit to PF07383, Protein of unknown function DUF1496, score 1.1e-64
550537008916	glutamate dehydrogenase; Provisional; Region: PRK09414
550537008917	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
550537008918	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
550537008919	NAD(P) binding site [chemical binding]; other site
550537008920	HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimerisation region, score 1.1e-86
550537008921	PS00074 Glu / Leu / Phe / Val dehydrogenases active site.
550537008922	HMMPfam hit to PF00208, Glu/Leu/Phe/Val dehydrogenase, C-terminal, score 4.1e-144
550537008923	DNA topoisomerase III; Provisional; Region: PRK07726
550537008924	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
550537008925	active site
550537008926	putative interdomain interaction site [polypeptide binding]; other site
550537008927	putative metal-binding site [ion binding]; other site
550537008928	putative nucleotide binding site [chemical binding]; other site
550537008929	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
550537008930	domain I; other site
550537008931	DNA binding groove [nucleotide binding]
550537008932	phosphate binding site [ion binding]; other site
550537008933	domain II; other site
550537008934	domain III; other site
550537008935	nucleotide binding site [chemical binding]; other site
550537008936	catalytic site [active]
550537008937	domain IV; other site
550537008938	HMMPfam hit to PF01131, DNA topoisomerase, type IA, central, score 5.5e-190
550537008939	PS00396 Prokaryotic DNA topoisomerase I active site.
550537008940	HMMPfam hit to PF01751, TOPRIM, score 6.8e-36
550537008941	selenophosphate synthetase; Provisional; Region: PRK00943
550537008942	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
550537008943	dimerization interface [polypeptide binding]; other site
550537008944	putative ATP binding site [chemical binding]; other site
550537008945	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal, score 6e-21
550537008946	HMMPfam hit to PF00586, AIR synthase related protein, score 3.8e-10
550537008947	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537008948	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
550537008949	putative FMN binding site [chemical binding]; other site
550537008950	HMMPfam hit to PF00881, Nitroreductase, score 5.7e-41
550537008951	protease 4; Provisional; Region: PRK10949
550537008952	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
550537008953	tandem repeat interface [polypeptide binding]; other site
550537008954	oligomer interface [polypeptide binding]; other site
550537008955	active site residues [active]
550537008956	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
550537008957	tandem repeat interface [polypeptide binding]; other site
550537008958	oligomer interface [polypeptide binding]; other site
550537008959	active site residues [active]
550537008960	1 probable transmembrane helix predicted for SEN1748 by TMHMM2.0 at aa 21-43
550537008961	HMMPfam hit to PF01343, Peptidase S49, score 8.5e-55
550537008962	HMMPfam hit to PF01343, Peptidase S49, score 1.7e-73
550537008963	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
550537008964	active site
550537008965	homodimer interface [polypeptide binding]; other site
550537008966	HMMPfam hit to PF00710, Asparaginase/glutaminase, score 7.8e-142
550537008967	PS00144 Asparaginase / glutaminase active site signature 1.
550537008968	PS00917 Asparaginase / glutaminase active site signature 2.
550537008969	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
550537008970	Isochorismatase family; Region: Isochorismatase; pfam00857
550537008971	catalytic triad [active]
550537008972	metal binding site [ion binding]; metal-binding site
550537008973	conserved cis-peptide bond; other site
550537008974	HMMPfam hit to PF00857, Isochorismatase hydrolase, score 2.3e-79
550537008975	benzoate transport; Region: 2A0115; TIGR00895
550537008976	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537008977	putative substrate translocation pore; other site
550537008978	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537008979	12 probable transmembrane helices predicted for SEN1751 by TMHMM2.0 at aa 45-67, 82-103, 116-138, 142-161, 173-195, 199-221, 288-310, 320-342, 349-366, 376-398, 411-433 and 438-460
550537008980	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.5e-31
550537008981	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537008982	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537008983	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537008984	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 7.7e-44
550537008985	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 1.3e-19
550537008986	PS00894 Bacterial regulatory proteins, deoR family signature.
550537008987	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537008988	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537008989	active site
550537008990	catalytic tetrad [active]
550537008991	HMMPfam hit to PF00248, Aldo/keto reductase, score 1.3e-42
550537008992	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
550537008993	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537008994	substrate binding site [chemical binding]; other site
550537008995	ATP binding site [chemical binding]; other site
550537008996	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 1.8e-79
550537008997	PS00017 ATP/GTP-binding site motif A (P-loop).
550537008998	PS00584 pfkB family of carbohydrate kinases signature 2.
550537008999	PS00583 pfkB family of carbohydrate kinases signature 1.
550537009000	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
550537009001	intersubunit interface [polypeptide binding]; other site
550537009002	active site
550537009003	zinc binding site [ion binding]; other site
550537009004	Na+ binding site [ion binding]; other site
550537009005	HMMPfam hit to PF01116, Ketose-bisphosphate aldolase, class-II, score 9.1e-69
550537009006	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
550537009007	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
550537009008	inhibitor binding site; inhibition site
550537009009	catalytic Zn binding site [ion binding]; other site
550537009010	structural Zn binding site [ion binding]; other site
550537009011	NADP binding site [chemical binding]; other site
550537009012	tetramer interface [polypeptide binding]; other site
550537009013	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 2.8e-39
550537009014	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 2.1e-41
550537009015	PS00693 Riboflavin synthase alpha chain family signature.
550537009016	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537009017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537009018	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537009019	12 probable transmembrane helices predicted for SEN1757 by TMHMM2.0 at aa 25-47, 60-82, 89-108, 112-134, 154-176, 180-202, 266-288, 301-323, 330-352, 356-378, 391-413 and 418-440
550537009020	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.9e-26
550537009021	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
550537009022	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
550537009023	putative NAD(P) binding site [chemical binding]; other site
550537009024	catalytic Zn binding site [ion binding]; other site
550537009025	structural Zn binding site [ion binding]; other site
550537009026	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 1.2e-40
550537009027	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 4.5e-37
550537009028	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537009030	HMMPfam hit to PF00704, Glycoside hydrolase, family 18, catalytic domain, score 8.4e-05
550537009031	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
550537009032	HMMPfam hit to PF07023, Protein of unknown function DUF1315, score 4.6e-59
550537009033	methionine sulfoxide reductase B; Provisional; Region: PRK00222
550537009034	SelR domain; Region: SelR; pfam01641
550537009035	HMMPfam hit to PF01641, Methionine sulphoxide reductase B, score 2.9e-87
550537009036	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
550537009037	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
550537009038	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
550537009039	HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, score 1.2e-98
550537009040	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
550537009041	HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, score 1.7e-117
550537009042	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
550537009043	active site
550537009044	phosphate binding residues; other site
550537009045	catalytic residues [active]
550537009046	HMMPfam hit to PF01263, Aldose 1-epimerase, score 3.8e-44
550537009047	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009048	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537009049	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537009050	active site
550537009051	catalytic tetrad [active]
550537009052	HMMPfam hit to PF00248, Aldo/keto reductase, score 1.6e-64
550537009053	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
550537009054	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537009055	FeS/SAM binding site; other site
550537009056	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
550537009057	HMMPfam hit to PF04055, Radical SAM, score 8.8e-09
550537009058	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
550537009059	HMMPfam hit to PF06629, MltA-interacting MipA, score 3.7e-99
550537009060	PrkA family serine protein kinase; Provisional; Region: PRK15455
550537009061	AAA ATPase domain; Region: AAA_16; pfam13191
550537009062	Walker A motif; other site
550537009063	ATP binding site [chemical binding]; other site
550537009064	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
550537009065	HMMPfam hit to PF08298, PrkA AAA, score 3.3e-271
550537009066	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009067	HMMPfam hit to PF06798, PrkA serine kinase, score 3.1e-181
550537009068	hypothetical protein; Provisional; Region: PRK05325
550537009069	HMMPfam hit to PF04285, Protein of unknown function DUF444, score 3.6e-282
550537009070	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
550537009071	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537009072	metal binding site [ion binding]; metal-binding site
550537009073	active site
550537009074	I-site; other site
550537009075	2 probable transmembrane helices predicted for SEN1769 by TMHMM2.0 at aa 7-29 and 305-327
550537009076	HMMPfam hit to PF00990, GGDEF, score 8.3e-42
550537009077	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
550537009078	putative deacylase active site [active]
550537009079	HMMPfam hit to PF04073, YbaK/prolyl-tRNA synthetase associated region, score 2.5e-48
550537009080	Predicted membrane protein [Function unknown]; Region: COG2707
550537009081	HMMPfam hit to PF04284, Protein of unknown function DUF441, transmembrame, score 1.5e-88
550537009082	4 probable transmembrane helices predicted for SEN1771 by TMHMM2.0 at aa 12-34, 49-71, 76-98 and 124-146
550537009083	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537009084	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537009085	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 1.6e-06
550537009086	PS00041 Bacterial regulatory proteins, araC family signature.
550537009087	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
550537009088	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537009089	12 probable transmembrane helices predicted for SEN1773 by TMHMM2.0 at aa 12-31, 46-68, 81-98, 103-125, 137-159, 163-185, 217-239, 249-271, 278-297, 302-324, 333-355 and 365-387
550537009090	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 7.4e-29
550537009091	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009092	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009093	Uncharacterized conserved protein [Function unknown]; Region: COG3189
550537009094	HMMPfam hit to PF04343, Protein of unknown function DUF488, score 1.1e-39
550537009095	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009096	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
550537009097	murein hydrolase B; Provisional; Region: PRK10760; cl17906
550537009098	Domain of unknown function (DUF333); Region: DUF333; pfam03891
550537009099	HMMPfam hit to PF03891, Protein of unknown function DUF333, score 6.1e-24
550537009100	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009101	hypothetical protein; Provisional; Region: PRK10457
550537009102	HMMPfam hit to PF04226, Transglycosylase-associated protein, score 2.9e-19
550537009103	3 probable transmembrane helices predicted for SEN1777 by TMHMM2.0 at aa 4-21, 28-50 and 60-77
550537009104	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009105	4 probable transmembrane helices predicted for SEN1779 by TMHMM2.0 at aa 7-25, 40-59, 71-90 and 100-122
550537009106	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
550537009107	HMMPfam hit to PF08956, Protein of unknown function DUF1869, score 3.5e-49
550537009108	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
550537009109	HMMPfam hit to PF09313, Protein of unknown function DUF1971, score 4.4e-37
550537009110	leucine export protein LeuE; Provisional; Region: PRK10958
550537009111	HMMPfam hit to PF01810, Lysine exporter protein (LYSE/YGGA), score 1.1e-60
550537009112	6 probable transmembrane helices predicted for SEN1782 by TMHMM2.0 at aa 10-32, 45-67, 77-99, 120-142, 157-179 and 191-210
550537009113	chorismate mutase; Provisional; Region: PRK08055
550537009114	HMMPfam hit to PF01817, Chorismate mutase, score 5.1e-13
550537009115	Pleckstrin homology-like domain; Region: PH-like; cl17171
550537009116	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
550537009117	transcriptional regulator MirA; Provisional; Region: PRK15043
550537009118	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
550537009119	DNA binding residues [nucleotide binding]
550537009120	dimer interface [polypeptide binding]; other site
550537009121	HMMPfam hit to PF00376, Bacterial regulatory protein, MerR, score 4.3e-10
550537009122	PS00552 Bacterial regulatory proteins, merR family signature.
550537009123	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537009124	DNA binding residues [nucleotide binding]
550537009125	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 3.3e-07
550537009126	aminoglycoside resistance protein; Provisional; Region: PRK13746
550537009127	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
550537009128	active site
550537009129	NTP binding site [chemical binding]; other site
550537009130	metal binding triad [ion binding]; metal-binding site
550537009131	antibiotic binding site [chemical binding]; other site
550537009132	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
550537009133	HMMPfam hit to PF01909, DNA polymerase, beta-like region, score 1.7e-11
550537009134	zinc/cadmium-binding protein; Provisional; Region: PRK10306
550537009135	HMMPfam hit to PF09223, YodA, score 5.9e-126
550537009136	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
550537009137	dimerization interface [polypeptide binding]; other site
550537009138	HMMPfam hit to PF03860, Protein of unknown function DUF326, score 0.06
550537009139	HMMPfam hit to PF03860, Protein of unknown function DUF326, score 0.0016
550537009140	HMMPfam hit to PF03860, Protein of unknown function DUF326, score 0.025
550537009141	HMMPfam hit to PF03860, Protein of unknown function DUF326, score 2.1
550537009142	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
550537009143	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537009144	5 probable transmembrane helices predicted for SEN1791 by TMHMM2.0 at aa 20-42, 74-90, 97-114, 136-158 and 165-187
550537009145	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 3.2e-75
550537009146	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537009147	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
550537009148	Walker A/P-loop; other site
550537009149	ATP binding site [chemical binding]; other site
550537009150	Q-loop/lid; other site
550537009151	ABC transporter signature motif; other site
550537009152	Walker B; other site
550537009153	D-loop; other site
550537009154	H-loop/switch region; other site
550537009155	HMMPfam hit to PF00005, ABC transporter related, score 1.1e-26
550537009156	PS00211 ABC transporters family signature.
550537009157	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009158	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537009159	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
550537009160	Walker A/P-loop; other site
550537009161	ATP binding site [chemical binding]; other site
550537009162	Q-loop/lid; other site
550537009163	ABC transporter signature motif; other site
550537009164	Walker B; other site
550537009165	D-loop; other site
550537009166	H-loop/switch region; other site
550537009167	HMMPfam hit to PF00005, ABC transporter related, score 2.7e-34
550537009168	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009169	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
550537009170	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537009171	dimer interface [polypeptide binding]; other site
550537009172	conserved gate region; other site
550537009173	putative PBP binding loops; other site
550537009174	ABC-ATPase subunit interface; other site
550537009175	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 4.6e-21
550537009176	4 probable transmembrane helices predicted for SEN1794 by TMHMM2.0 at aa 7-29, 74-96, 117-139 and 236-253
550537009177	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
550537009178	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537009179	dimer interface [polypeptide binding]; other site
550537009180	conserved gate region; other site
550537009181	ABC-ATPase subunit interface; other site
550537009182	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 3e-53
550537009183	4 probable transmembrane helices predicted for SEN1795 by TMHMM2.0 at aa 7-29, 104-126, 139-161 and 291-313
550537009184	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
550537009185	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
550537009186	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 1.3e-82
550537009187	1 probable transmembrane helix predicted for SEN1796 by TMHMM2.0 at aa 21-40
550537009188	TRL-like protein family; Region: TRL; pfam13146
550537009189	1 probable transmembrane helix predicted for SEN1797 by TMHMM2.0 at aa 7-29
550537009190	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009191	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
550537009192	HMMPfam hit to PF01292, Cytochrome B561, bacterial, score 2.1e-59
550537009193	4 probable transmembrane helices predicted for SEN1798 by TMHMM2.0 at aa 9-31, 46-63, 88-110 and 140-162
550537009194	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
550537009195	BNR repeat-like domain; Region: BNR_2; pfam13088
550537009196	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 13
550537009197	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 33
550537009198	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 32
550537009199	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 13
550537009200	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
550537009201	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
550537009202	putative dimer interface [polypeptide binding]; other site
550537009203	HMMPfam hit to PF00011, Heat shock protein Hsp20, score 1.2e-12
550537009204	lysozyme inhibitor; Provisional; Region: PRK13791
550537009205	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
550537009206	HMMPfam hit to PF06316, Virulence-related outer membrane protein, score 7e-21
550537009207	PS00695 Enterobacterial virulence outer membrane protein signature 2.
550537009208	PS00694 Enterobacterial virulence outer membrane protein signature 1.
550537009209	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
550537009210	DNA-binding site [nucleotide binding]; DNA binding site
550537009211	RNA-binding motif; other site
550537009212	HMMPfam hit to PF00313, Cold-shock protein, DNA-binding, score 8.6e-23
550537009213	Ricin-type beta-trefoil; Region: RICIN; smart00458
550537009214	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
550537009215	putative sugar binding sites [chemical binding]; other site
550537009216	Q-X-W motif; other site
550537009217	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009218	HMMPfam hit to PF00652, Ricin B lectin, score 4.6e-28
550537009219	DinI-like family; Region: DinI; pfam06183
550537009220	HMMPfam hit to PF06183, DinI-like, score 2.2e-31
550537009221	Note the premature stop codon following residue 226
550537009222	CDS has suffered many deletion events
550537009223	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 8.3e-08
550537009224	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
550537009225	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009226	isocitrate dehydrogenase; Validated; Region: PRK07362
550537009227	isocitrate dehydrogenase; Reviewed; Region: PRK07006
550537009228	HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 3.4e-164
550537009229	PS00470 Isocitrate and isopropylmalate dehydrogenases signature.
550537009230	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
550537009231	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
550537009232	probable active site [active]
550537009233	HMMPfam hit to PF00849, Pseudouridine synthase, score 1.2e-21
550537009234	PS01149 Rsu family of pseudouridine synthase signature.
550537009235	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
550537009236	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
550537009237	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
550537009238	nudix motif; other site
550537009239	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 3.9e-28
550537009240	PS00893 mutT domain signature.
550537009241	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
550537009242	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
550537009243	HMMPfam hit to PF03054, tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase, score 4.9e-235
550537009244	PS00070 Aldehyde dehydrogenases cysteine active site.
550537009245	putative lysogenization regulator; Reviewed; Region: PRK00218
550537009246	HMMPfam hit to PF04356, Protein of unknown function DUF489, score 4e-140
550537009247	adenylosuccinate lyase; Provisional; Region: PRK09285
550537009248	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
550537009249	tetramer interface [polypeptide binding]; other site
550537009250	active site
550537009251	HMMPfam hit to PF00206, Fumarate lyase, score 6.3e-111
550537009252	PS00163 Fumarate lyases signature.
550537009253	HMMPfam hit to PF08328, Adenylosuccinate lyase C-terminal, score 1.8e-89
550537009254	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
550537009255	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537009256	active site
550537009257	phosphorylation site [posttranslational modification]
550537009258	intermolecular recognition site; other site
550537009259	dimerization interface [polypeptide binding]; other site
550537009260	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537009261	DNA binding site [nucleotide binding]
550537009262	HMMPfam hit to PF00072, Response regulator receiver, score 7.7e-32
550537009263	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 1.3e-17
550537009264	sensor protein PhoQ; Provisional; Region: PRK10815
550537009265	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
550537009266	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
550537009267	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537009268	ATP binding site [chemical binding]; other site
550537009269	Mg2+ binding site [ion binding]; other site
550537009270	G-X-G motif; other site
550537009271	HMMPfam hit to PF08918, PhoQ Sensor, score 1.4e-126
550537009272	2 probable transmembrane helices predicted for SEN1819 by TMHMM2.0 at aa 20-42 and 194-216
550537009273	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 7.7e-09
550537009274	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 0.00076
550537009275	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 6.4e-28
550537009276	Uncharacterized conserved protein [Function unknown]; Region: COG2850
550537009277	Cupin domain; Region: Cupin_2; cl17218
550537009278	HMMPfam hit to PF08007, Cupin 4, score 5.7e-152
550537009279	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 0.0016
550537009280	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
550537009281	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
550537009282	metal binding site [ion binding]; metal-binding site
550537009283	dimer interface [polypeptide binding]; other site
550537009284	HMMPfam hit to PF01546, Peptidase M20, score 1.1e-17
550537009285	HMMPfam hit to PF07687, Peptidase M20, dimerisation, score 1.2e-28
550537009286	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
550537009287	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
550537009288	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
550537009289	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537009290	Walker A/P-loop; other site
550537009291	ATP binding site [chemical binding]; other site
550537009292	Q-loop/lid; other site
550537009293	ABC transporter signature motif; other site
550537009294	Walker B; other site
550537009295	D-loop; other site
550537009296	H-loop/switch region; other site
550537009297	TOBE domain; Region: TOBE_2; pfam08402
550537009298	HMMPfam hit to PF00005, ABC transporter related, score 8.2e-66
550537009299	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009300	PS00211 ABC transporters family signature.
550537009301	HMMPfam hit to PF08402, Transport-associated OB, type 2, score 1.2e-07
550537009302	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
550537009303	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537009304	dimer interface [polypeptide binding]; other site
550537009305	conserved gate region; other site
550537009306	putative PBP binding loops; other site
550537009307	ABC-ATPase subunit interface; other site
550537009308	6 probable transmembrane helices predicted for SEN1824 by TMHMM2.0 at aa 9-31, 69-91, 98-120, 151-173, 194-216 and 250-272
550537009309	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 4.9e-14
550537009310	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009311	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537009312	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009313	Sif protein; Region: Sif; pfam06767
550537009314	HMMPfam hit to PF06767, Sif, score 1.1e-242
550537009315	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
550537009316	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537009317	dimer interface [polypeptide binding]; other site
550537009318	conserved gate region; other site
550537009319	putative PBP binding loops; other site
550537009320	ABC-ATPase subunit interface; other site
550537009321	6 probable transmembrane helices predicted for SEN1826 by TMHMM2.0 at aa 5-27, 64-86, 99-121, 126-148, 176-195 and 230-252
550537009322	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.5e-13
550537009323	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537009324	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
550537009325	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
550537009326	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 6.3e-12
550537009327	NAD-dependent deacetylase; Provisional; Region: PRK00481
550537009328	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
550537009329	NAD+ binding site [chemical binding]; other site
550537009330	substrate binding site [chemical binding]; other site
550537009331	Zn binding site [ion binding]; other site
550537009332	HMMPfam hit to PF02146, Silent information regulator protein Sir2, score 2.6e-86
550537009333	fructokinase; Reviewed; Region: PRK09557
550537009334	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537009335	nucleotide binding site [chemical binding]; other site
550537009336	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537009337	HMMPfam hit to PF00480, ROK, score 3.8e-56
550537009338	PS01125 ROK family signature.
550537009339	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
550537009340	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
550537009341	FtsX-like permease family; Region: FtsX; pfam02687
550537009342	HMMPfam hit to PF02687, Protein of unknown function DUF214, permase predicted, score 3.3e-50
550537009343	PS00027 'Homeobox' domain signature.
550537009344	4 probable transmembrane helices predicted for SEN1830 by TMHMM2.0 at aa 21-43, 270-292, 318-340 and 375-397
550537009345	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009346	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
550537009347	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
550537009348	Walker A/P-loop; other site
550537009349	ATP binding site [chemical binding]; other site
550537009350	Q-loop/lid; other site
550537009351	ABC transporter signature motif; other site
550537009352	Walker B; other site
550537009353	D-loop; other site
550537009354	H-loop/switch region; other site
550537009355	HMMPfam hit to PF00005, ABC transporter related, score 1.2e-65
550537009356	PS00211 ABC transporters family signature.
550537009357	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009358	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
550537009359	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
550537009360	FtsX-like permease family; Region: FtsX; pfam02687
550537009361	HMMPfam hit to PF02687, Protein of unknown function DUF214, permase predicted, score 3e-48
550537009362	4 probable transmembrane helices predicted for SEN1832 by TMHMM2.0 at aa 25-47, 266-288, 318-340 and 360-382
550537009363	transcription-repair coupling factor; Provisional; Region: PRK10689
550537009364	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
550537009365	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537009366	ATP binding site [chemical binding]; other site
550537009367	putative Mg++ binding site [ion binding]; other site
550537009368	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537009369	nucleotide binding region [chemical binding]; other site
550537009370	ATP-binding site [chemical binding]; other site
550537009371	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
550537009372	HMMPfam hit to PF02559, Transcription factor CarD, score 2.6e-49
550537009373	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 4.9e-43
550537009374	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009375	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 1.6e-21
550537009376	HMMPfam hit to PF03461, TRCF, score 5.1e-56
550537009377	L,D-transpeptidase; Provisional; Region: PRK10190
550537009378	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537009379	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
550537009380	1 probable transmembrane helix predicted for SEN1834 by TMHMM2.0 at aa 7-29
550537009381	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 4e-08
550537009382	HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 1.3e-66
550537009383	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537009384	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 4.5e-23
550537009385	1 probable transmembrane helix predicted for SEN1835 by TMHMM2.0 at aa 7-29
550537009386	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
550537009387	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537009388	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 1e-15
550537009389	hypothetical protein; Provisional; Region: PRK11280
550537009390	HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 1.3e-14
550537009391	1 probable transmembrane helix predicted for SEN1837 by TMHMM2.0 at aa 5-27
550537009392	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
550537009393	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537009394	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 1.9e-32
550537009395	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 1.9e-23
550537009396	hypothetical protein; Provisional; Region: PRK04940
550537009397	HMMPfam hit to PF05728, Protein of unknown function UPF0227, score 1.2e-106
550537009398	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
550537009399	beta-hexosaminidase; Provisional; Region: PRK05337
550537009400	HMMPfam hit to PF00933, Glycoside hydrolase, family 3, N-terminal, score 1.5e-83
550537009401	PS00775 Glycosyl hydrolases family 3 active site.
550537009402	thiamine kinase; Region: ycfN_thiK; TIGR02721
550537009403	thiamine kinase; Provisional; Region: thiK; PRK10271
550537009404	substrate binding site [chemical binding]; other site
550537009405	HMMPfam hit to PF01636, Aminoglycoside phosphotransferase, score 2.6e-27
550537009406	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009407	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
550537009408	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009409	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
550537009410	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
550537009411	putative dimer interface [polypeptide binding]; other site
550537009412	HMMPfam hit to PF07233, Protein of unknown function DUF1425, score 1.6e-58
550537009413	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009414	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
550537009415	nucleotide binding site/active site [active]
550537009416	HIT family signature motif; other site
550537009417	catalytic residue [active]
550537009418	HMMPfam hit to PF01230, Histidine triad (HIT) protein, score 1e-47
550537009419	PS00892 HIT family signature.
550537009420	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
550537009421	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537009422	N-terminal plug; other site
550537009423	ligand-binding site [chemical binding]; other site
550537009424	PS00430 TonB-dependent receptor proteins signature 1.
550537009425	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 4.9e-19
550537009426	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 1e-26
550537009427	PS01156 TonB-dependent receptor proteins signature 2.
550537009428	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
550537009429	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
550537009430	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
550537009431	active site turn [active]
550537009432	phosphorylation site [posttranslational modification]
550537009433	HMMPfam hit to PF00367, Phosphotransferase system, EIIB, score 2.7e-18
550537009434	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
550537009435	9 probable transmembrane helices predicted for SEN1846 by TMHMM2.0 at aa 15-37, 49-71, 81-103, 116-138, 153-175, 248-270, 280-302, 309-331 and 354-376
550537009436	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 6.7e-109
550537009437	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
550537009438	active site
550537009439	HMMPfam hit to PF01026, Deoxyribonuclease, TatD-related, score 1.9e-120
550537009440	PS01091 Uncharacterized protein family UPF0006 signature 3.
550537009441	PS01137 Uncharacterized protein family UPF0006 signature 1.
550537009442	DNA polymerase III subunit delta'; Validated; Region: PRK07993
550537009443	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
550537009444	HMMPfam hit to PF09115, DNA polymerase III, delta subunit, C-terminal, score 8.2e-51
550537009445	thymidylate kinase; Validated; Region: tmk; PRK00698
550537009446	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
550537009447	TMP-binding site; other site
550537009448	ATP-binding site [chemical binding]; other site
550537009449	HMMPfam hit to PF02223, Thymidylate kinase, score 4.6e-85
550537009450	PS01331 Thymidylate kinase signature.
550537009451	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009452	conserved hypothetical protein, YceG family; Region: TIGR00247
550537009453	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
550537009454	dimerization interface [polypeptide binding]; other site
550537009455	HMMPfam hit to PF02618, Aminodeoxychorismate lyase, score 9.5e-153
550537009456	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
550537009457	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
550537009458	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537009459	catalytic residue [active]
550537009460	HMMPfam hit to PF01063, Aminotransferase, class IV, score 6.8e-44
550537009461	PS00770 Aminotransferases class-IV signature.
550537009462	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
550537009463	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
550537009464	dimer interface [polypeptide binding]; other site
550537009465	active site
550537009466	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal, score 9.5e-59
550537009467	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal, score 2.3e-75
550537009468	PS00606 Beta-ketoacyl synthases active site.
550537009469	acyl carrier protein; Provisional; Region: acpP; PRK00982
550537009470	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537009471	HMMPfam hit to PF00550, Phosphopantetheine-binding, score 4.3e-24
550537009472	PS00012 Phosphopantetheine attachment site.
550537009473	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
550537009474	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
550537009475	NAD(P) binding site [chemical binding]; other site
550537009476	homotetramer interface [polypeptide binding]; other site
550537009477	homodimer interface [polypeptide binding]; other site
550537009478	active site
550537009479	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 2.4e-41
550537009480	PS00061 Short-chain dehydrogenases/reductases family signature.
550537009481	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
550537009482	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
550537009483	HMMPfam hit to PF00698, Acyl transferase, score 1.8e-20
550537009484	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
550537009485	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
550537009486	dimer interface [polypeptide binding]; other site
550537009487	active site
550537009488	CoA binding pocket [chemical binding]; other site
550537009489	HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal, score 1.1e-52
550537009490	HMMPfam hit to PF08545, 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, score 1.3e-43
550537009491	putative phosphate acyltransferase; Provisional; Region: PRK05331
550537009492	HMMPfam hit to PF02504, Fatty acid synthesis plsX protein, score 6.1e-178
550537009493	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
550537009494	HMMPfam hit to PF01783, Ribosomal protein L32p, score 2.3e-20
550537009495	hypothetical protein; Provisional; Region: PRK11193
550537009496	HMMPfam hit to PF02620, Protein of unknown function DUF177, score 6.8e-57
550537009497	Maf-like protein; Region: Maf; pfam02545
550537009498	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
550537009499	active site
550537009500	dimer interface [polypeptide binding]; other site
550537009501	HMMPfam hit to PF02545, Maf-like protein, score 8.4e-90
550537009502	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
550537009503	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009504	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
550537009505	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537009506	RNA binding surface [nucleotide binding]; other site
550537009507	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
550537009508	active site
550537009509	HMMPfam hit to PF00849, Pseudouridine synthase, score 2e-61
550537009510	PS01129 Rlu family of pseudouridine synthase signature.
550537009511	HMMPfam hit to PF01479, RNA-binding S4, score 3.9e-11
550537009512	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
550537009513	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
550537009514	homodimer interface [polypeptide binding]; other site
550537009515	oligonucleotide binding site [chemical binding]; other site
550537009516	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
550537009517	HMMPfam hit to PF00575, S1, RNA binding, score 6.1e-19
550537009518	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009519	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
550537009520	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
550537009521	HMMPfam hit to PF00669, Flagellin, N-terminal, score 8e-40
550537009522	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
550537009523	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
550537009524	HMMPfam hit to PF06429, Protein of unknown function DUF1078, C-terminal, score 5.1e-16
550537009525	HMMPfam hit to PF00460, Flagellar basal body rod protein, score 1.1e-10
550537009526	PS00588 Flagella basal body rod proteins signature.
550537009527	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
550537009528	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
550537009529	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
550537009530	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase, score 1.3e-69
550537009531	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
550537009532	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
550537009533	HMMPfam hit to PF02119, Flagellar P-ring protein, score 1.3e-243
550537009534	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
550537009535	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
550537009536	HMMPfam hit to PF02107, Flagellar L-ring protein, score 1e-117
550537009537	1 probable transmembrane helix predicted for SEN1868 by TMHMM2.0 at aa 5-27
550537009538	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009539	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
550537009540	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
550537009541	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
550537009542	HMMPfam hit to PF06429, Protein of unknown function DUF1078, C-terminal, score 1.6e-19
550537009543	HMMPfam hit to PF00460, Flagellar basal body rod protein, score 5.4e-15
550537009544	PS00588 Flagella basal body rod proteins signature.
550537009545	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
550537009546	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
550537009547	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
550537009548	HMMPfam hit to PF06429, Protein of unknown function DUF1078, C-terminal, score 0.002
550537009549	HMMPfam hit to PF00460, Flagellar basal body rod protein, score 3.7e-11
550537009550	PS00588 Flagella basal body rod proteins signature.
550537009551	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
550537009552	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
550537009553	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
550537009554	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
550537009555	HMMPfam hit to PF06429, Protein of unknown function DUF1078, C-terminal, score 6.8e-20
550537009556	HMMPfam hit to PF07559, Flagellar basal body FlaE, score 1.9e-26
550537009557	HMMPfam hit to PF00460, Flagellar basal body rod protein, score 8.7e-13
550537009558	PS00588 Flagella basal body rod proteins signature.
550537009559	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
550537009560	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
550537009561	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
550537009562	HMMPfam hit to PF03963, Flagellar hook capping protein, score 1.8e-51
550537009563	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
550537009564	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
550537009565	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
550537009566	HMMPfam hit to PF06429, Protein of unknown function DUF1078, C-terminal, score 1.9e-06
550537009567	HMMPfam hit to PF00460, Flagellar basal body rod protein, score 1.8e-11
550537009568	PS00588 Flagella basal body rod proteins signature.
550537009569	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
550537009570	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
550537009571	HMMPfam hit to PF00460, Flagellar basal body rod protein, score 2.2e-12
550537009572	PS00588 Flagella basal body rod proteins signature.
550537009573	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
550537009574	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
550537009575	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
550537009576	HMMPfam hit to PF08666, SAF domain, score 4.7e-11
550537009577	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
550537009578	HMMPfam hit to PF04316, Anti-sigma-28 factor, FlgM, score 1e-27
550537009579	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
550537009580	HMMPfam hit to PF05130, FlgN, score 5.5e-59
550537009581	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
550537009582	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
550537009583	13 probable transmembrane helices predicted for SEN1878 by TMHMM2.0 at aa 39-58, 95-117, 143-165, 172-194, 199-221, 250-272, 287-309, 322-341, 361-383, 396-415, 420-442, 454-476 and 491-513
550537009584	HMMPfam hit to PF03023, Virulence factor MVIN-like, score 7.2e-215
550537009585	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009586	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
550537009587	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
550537009588	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
550537009589	HMMPfam hit to PF02894, Oxidoreductase, C-terminal, score 3e-07
550537009590	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537009591	HMMPfam hit to PF01408, Oxidoreductase, N-terminal, score 8.5e-39
550537009592	hypothetical protein; Provisional; Region: PRK11239
550537009593	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
550537009594	HMMPfam hit to PF04337, Protein of unknown function DUF480, score 1.6e-128
550537009595	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009596	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
550537009597	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
550537009598	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 8.5e-14
550537009599	multidrug resistance protein MdtH; Provisional; Region: PRK11646
550537009600	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537009601	putative substrate translocation pore; other site
550537009602	10 probable transmembrane helices predicted for SEN1882 by TMHMM2.0 at aa 13-35, 99-116, 136-158, 163-185, 210-232, 247-264, 277-295, 300-322, 335-357 and 367-389
550537009603	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5e-46
550537009604	glutaredoxin 2; Provisional; Region: PRK10387
550537009605	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
550537009606	C-terminal domain interface [polypeptide binding]; other site
550537009607	GSH binding site (G-site) [chemical binding]; other site
550537009608	catalytic residues [active]
550537009609	putative dimer interface [polypeptide binding]; other site
550537009610	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
550537009611	N-terminal domain interface [polypeptide binding]; other site
550537009612	HMMPfam hit to PF00462, Glutaredoxin, score 1.2e-05
550537009613	PS00195 Glutaredoxin active site.
550537009614	HMMPfam hit to PF04399, Glutaredoxin 2, C-terminal, score 7.1e-78
550537009615	lipoprotein; Provisional; Region: PRK10598
550537009616	HMMPfam hit to PF07273, Protein of unknown function DUF1439, score 6.6e-128
550537009617	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009618	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
550537009619	active site
550537009620	substrate binding pocket [chemical binding]; other site
550537009621	dimer interface [polypeptide binding]; other site
550537009622	HMMPfam hit to PF01979, Amidohydrolase 1, score 7.8e-33
550537009623	PS00482 Dihydroorotase signature 1.
550537009624	PS00483 Dihydroorotase signature 2.
550537009625	DNA damage-inducible protein I; Provisional; Region: PRK10597
550537009626	HMMPfam hit to PF06183, DinI-like, score 1.7e-35
550537009627	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
550537009628	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
550537009629	hydroxyglutarate oxidase; Provisional; Region: PRK11728
550537009630	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 7.3e-61
550537009631	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009632	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
550537009633	1 probable transmembrane helix predicted for SEN1889 by TMHMM2.0 at aa 15-36
550537009634	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
550537009635	HMMPfam hit to PF01292, Cytochrome B561, bacterial, score 1.6e-65
550537009636	4 probable transmembrane helices predicted for SEN1890 by TMHMM2.0 at aa 13-35, 55-72, 92-114 and 147-169
550537009637	hypothetical protein; Provisional; Region: PRK03757
550537009638	HMMPfam hit to PF04264, Lipid/polyisoprenoid-binding, YceI-like, score 6e-84
550537009639	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
550537009640	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
550537009641	active site residue [active]
550537009642	HMMPfam hit to PF00581, Rhodanese-like, score 1.7e-28
550537009643	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009644	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
550537009645	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
550537009646	putative acyl-acceptor binding pocket; other site
550537009647	HMMPfam hit to PF03279, Bacterial lipid A biosynthesis acyltransferase, score 3.5e-155
550537009648	2 probable transmembrane helices predicted for SEN1893 by TMHMM2.0 at aa 20-42 and 123-145
550537009649	drug efflux system protein MdtG; Provisional; Region: PRK09874
550537009650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537009651	putative substrate translocation pore; other site
550537009652	11 probable transmembrane helices predicted for SEN1894 by TMHMM2.0 at aa 15-37, 49-68, 83-101, 108-130, 140-162, 169-191, 222-244, 251-273, 288-306, 313-335 and 371-393
550537009653	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 9.7e-51
550537009654	secY/secA suppressor protein; Provisional; Region: PRK11467
550537009655	lipoprotein; Provisional; Region: PRK10175
550537009656	HMMPfam hit to PF07119, Protein of unknown function DUF1375, score 4.4e-36
550537009657	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009658	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
550537009659	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
550537009660	Ligand binding site; other site
550537009661	DXD motif; other site
550537009662	6 probable transmembrane helices predicted for SEN1897 by TMHMM2.0 at aa 139-156, 194-216, 512-534, 568-590, 603-625 and 680-702
550537009663	PS00213 Lipocalin signature.
550537009664	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 2.4e-13
550537009665	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
550537009666	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
550537009667	HMMPfam hit to PF04349, Glucan biosynthesis, periplasmic, MdoG C-terminal, score 0
550537009668	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
550537009669	Acyltransferase family; Region: Acyl_transf_3; pfam01757
550537009670	HMMPfam hit to PF01757, Acyltransferase 3, score 1.4e-49
550537009671	10 probable transmembrane helices predicted for SEN1899 by TMHMM2.0 at aa 17-39, 54-76, 88-110, 137-159, 176-198, 213-232, 245-262, 277-299, 306-328 and 338-360
550537009672	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
550537009673	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
550537009674	putative active site [active]
550537009675	catalytic site [active]
550537009676	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
550537009677	putative active site [active]
550537009678	catalytic site [active]
550537009679	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 0.0051
550537009680	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 0.36
550537009681	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
550537009682	putative ADP-ribose binding site [chemical binding]; other site
550537009683	putative active site [active]
550537009684	HMMPfam hit to PF01661, Appr-1-p processing, score 4.8e-69
550537009685	Fimbrial protein; Region: Fimbrial; cl01416
550537009686	fimbrial operon csg
550537009687	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
550537009688	major curlin subunit; Provisional; Region: csgA; PRK10051
550537009689	Curlin associated repeat; Region: Curlin_rpt; pfam07012
550537009690	HMMPfam hit to PF07012, Curlin associated, score 0.0013
550537009691	HMMPfam hit to PF07012, Curlin associated, score 2.9e-13
550537009692	HMMPfam hit to PF07012, Curlin associated, score 1.9e-11
550537009693	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
550537009694	Curlin associated repeat; Region: Curlin_rpt; pfam07012
550537009695	Curlin associated repeat; Region: Curlin_rpt; pfam07012
550537009696	HMMPfam hit to PF07012, Curlin associated, score 4.5e-11
550537009697	HMMPfam hit to PF07012, Curlin associated, score 2.4e-12
550537009698	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
550537009699	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537009700	DNA binding residues [nucleotide binding]
550537009701	dimerization interface [polypeptide binding]; other site
550537009702	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 2.1e-21
550537009703	PS00622 Bacterial regulatory proteins, luxR family signature.
550537009704	curli assembly protein CsgE; Provisional; Region: PRK10386
550537009705	curli assembly protein CsgF; Provisional; Region: PRK10050
550537009706	1 probable transmembrane helix predicted for SEN1908 by TMHMM2.0 at aa 7-26
550537009707	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
550537009708	HMMPfam hit to PF03783, Curli production assembly/transport component CsgG, score 5.1e-106
550537009709	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
550537009710	HMMPfam hit to PF06496, Protein of unknown function DUF1097, score 5e-101
550537009711	6 probable transmembrane helices predicted for SEN1910 by TMHMM2.0 at aa 12-31, 36-58, 65-84, 88-110, 115-134 and 139-161
550537009712	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009713	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009714	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
550537009715	HMMPfam hit to PF06192, Cytoplasmic chaperone TorD, score 2.4e-39
550537009716	putative hydrolase; Validated; Region: PRK09248
550537009717	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
550537009718	active site
550537009719	HMMPfam hit to PF02811, PHP, C-terminal, score 2.2e-41
550537009720	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
550537009721	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
550537009722	putative ligand binding site [chemical binding]; other site
550537009723	NAD binding site [chemical binding]; other site
550537009724	dimerization interface [polypeptide binding]; other site
550537009725	catalytic site [active]
550537009726	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding, score 4.1e-48
550537009727	Transposase; Region: DEDD_Tnp_IS110; pfam01548
550537009728	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
550537009729	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
550537009730	HMMPfam hit to PF02371, Transposase, IS116/IS110/IS902, score 4.6e-25
550537009731	HMMPfam hit to PF01548, Transposase, IS111A/IS1328/IS1533, score 5.2e-06
550537009732	1 probable transmembrane helix predicted for SEN1916 by TMHMM2.0 at aa 218-240
550537009733	Prophage SE20; highly similar in sequence and gene order to the Salmonella typhimurium DT64 phage ST64B
550537009734	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
550537009735	DNA-binding interface [nucleotide binding]; DNA binding site
550537009736	HMMPfam hit to PF02796, Resolvase, helix-turn-helix region, score 2.3e-09
550537009737	type III secretion system protein; Provisional; Region: PRK15383
550537009738	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
550537009739	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
550537009740	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 1.6e-34
550537009741	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
550537009742	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
550537009743	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
550537009744	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009745	HMMPfam hit to PF04865, Phage baseplate assembly predicted J-like, score 1.9e-68
550537009746	Phage protein GP46; Region: GP46; pfam07409
550537009747	HMMPfam hit to PF07409, Phage GP46, score 5.4e-76
550537009748	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
550537009749	HMMPfam hit to PF06890, Bacteriophage Mu Gp45, score 5.1e-92
550537009750	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
550537009751	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
550537009752	HMMPfam hit to PF06893, Bacteriophage Mu P, score 2.1e-214
550537009753	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
550537009754	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
550537009755	HMMPfam hit to PF07157, DNA circulation, N-terminal, score 2.8e-61
550537009756	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
550537009757	1 probable transmembrane helix predicted for SEN1929 by TMHMM2.0 at aa 35-57
550537009758	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
550537009759	Phage tail tube protein; Region: Tail_tube; pfam10618
550537009760	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
550537009761	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
550537009762	HMMPfam hit to PF06274, Bacteriophage Mu tail sheath, score 0
550537009763	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
550537009764	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
550537009765	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
550537009766	oligomerization interface [polypeptide binding]; other site
550537009767	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
550537009768	Phage capsid family; Region: Phage_capsid; pfam05065
550537009769	HMMPfam hit to PF05065, Phage major capsid protein, HK97, score 8.4e-107
550537009770	PS00012 Phosphopantetheine attachment site.
550537009771	Phage head maturation protease [General function prediction only]; Region: COG3740
550537009772	HMMPfam hit to PF04586, Peptidase U35, phage prohead HK97, score 4.3e-68
550537009773	Phage-related protein [Function unknown]; Region: COG4695
550537009774	Phage portal protein; Region: Phage_portal; pfam04860
550537009775	HMMPfam hit to PF04860, Phage portal protein, score 5.6e-78
550537009776	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
550537009777	HMMPfam hit to PF03354, Phage Terminase, score 3.4e-115
550537009778	Phage terminase, small subunit; Region: Terminase_4; pfam05119
550537009779	HMMPfam hit to PF05119, Phage terminase, small subunit, , P27, score 8.7e-10
550537009780	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
550537009781	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
550537009782	active site
550537009783	HMMPfam hit to PF01844, HNH endonuclease, score 1.3e-13
550537009784	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
550537009785	1 probable transmembrane helix predicted for SEN1942 by TMHMM2.0 at aa 15-32
550537009786	Predicted chitinase [General function prediction only]; Region: COG3179
550537009787	HMMPfam hit to PF00182, Glycoside hydrolase, family 19, catalytic, score 6.1e-06
550537009788	3 probable transmembrane helices predicted for SEN1944 by TMHMM2.0 at aa 20-42, 54-73 and 88-105
550537009789	4 probable transmembrane helices predicted for SEN1945 by TMHMM2.0 at aa 19-41, 51-73, 114-136 and 159-181
550537009790	Antitermination protein; Region: Antiterm; pfam03589
550537009791	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
550537009792	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
550537009793	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
550537009794	HMMPfam hit to PF03589, Antitermination protein, score 7.2e-52
550537009795	PS00190 Cytochrome c family heme-binding site signature.
550537009796	HMMPfam hit to PF03589, Antitermination protein, score 9.9e-45
550537009797	Protein of unknown function (DUF968); Region: DUF968; pfam06147
550537009798	HMMPfam hit to PF06914, Protein of unknown function DUF1277, score 5.5e-181
550537009799	KilA-N domain; Region: KilA-N; pfam04383
550537009800	HMMPfam hit to PF04383, KilA, N-terminal, score 2.4e-10
550537009801	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
550537009802	HMMPfam hit to PF05866, Endodeoxyribonuclease RusA, score 1.5e-41
550537009803	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
550537009804	HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA methyltransferase, score 7.5e-54
550537009805	PS00092 N-6 Adenine-specific DNA methylases signature.
550537009806	PerC transcriptional activator; Region: PerC; pfam06069
550537009807	Conserved phage C-terminus (Phg_2220_C); Region: Phg_2220_C; pfam09524
550537009808	Ash protein family; Region: Phage_ASH; pfam10554
550537009809	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
550537009810	Predicted transcriptional regulator [Transcription]; Region: COG2932
550537009811	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537009812	non-specific DNA binding site [nucleotide binding]; other site
550537009813	salt bridge; other site
550537009814	sequence-specific DNA binding site [nucleotide binding]; other site
550537009815	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
550537009816	Catalytic site [active]
550537009817	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 6.1e-13
550537009818	HMMPfam hit to PF00717, Peptidase S24, S26A and S26B, C-terminal, score 9.9e-19
550537009819	BssS protein family; Region: BssS; pfam13991
550537009820	recombination associated protein; Reviewed; Region: rdgC; PRK00321
550537009821	HMMPfam hit to PF04381,  exonuclease, RdgC, score 2.4e-149
550537009822	HD domain; Region: HD_3; cl17350
550537009823	Protein of unknown function DUF262; Region: DUF262; pfam03235
550537009824	Uncharacterized conserved protein [Function unknown]; Region: COG1479
550537009825	HMMPfam hit to PF03235, Protein of unknown function DUF262, score 6.4e-05
550537009826	Protein of unknown function (DUF551); Region: DUF551; pfam04448
550537009827	HMMPfam hit to PF04448, Protein of unknown function DUF551, score 8e-16
550537009828	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
550537009829	active site
550537009830	catalytic site [active]
550537009831	substrate binding site [chemical binding]; other site
550537009832	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
550537009833	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
550537009834	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
550537009835	dimer interface [polypeptide binding]; other site
550537009836	active site
550537009837	Int/Topo IB signature motif; other site
550537009838	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 0.00032
550537009839	repeated at location 2018460..2018520; probably a consequence of the ST64B-like paheg insertion
550537009840	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
550537009841	HMMPfam hit to PF06167, Protein of unknown function DUF980, score 3.9e-144
550537009842	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537009843	Has suffered multiple deletion events
550537009844	ROD21,  Genomic Island;bounded by 30bp repeats
550537009845	integrase; Provisional; Region: PRK09692
550537009846	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
550537009847	active site
550537009848	Int/Topo IB signature motif; other site
550537009849	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 1.6e-26
550537009851	1 probable transmembrane helix predicted for SEN1973 by TMHMM2.0 at aa 71-93
550537009852	TIR domain; Region: TIR_2; pfam13676
550537009853	HMMPfam hit to PF01582, Toll-Interleukin receptor, score 3.2e-07
550537009855	HMMPfam hit to PF04917, Bacterial shufflon protein, N-terminal, score 2.4e-08
550537009856	HMMPfam hit to PF07484, Phage Tail Collar, score 1.5e-18
550537009857	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009858	PS00409 Prokaryotic N-terminal methylation site.
550537009859	1 probable transmembrane helix predicted for SEN1977 by TMHMM2.0 at aa 20-39
550537009860	PilS N terminal; Region: PilS; pfam08805
550537009861	HMMPfam hit to PF08805, PilS N terminal, score 4e-56
550537009862	HMMPfam hit to PF07963, Prepilin-type cleavage/methylation, N-terminal, score 0.0013
550537009863	1 probable transmembrane helix predicted for SEN1978 by TMHMM2.0 at aa 13-35
550537009864	PS00409 Prokaryotic N-terminal methylation site.
550537009865	Conjugal transfer protein TraD; Region: TraD; pfam06412
550537009866	MobA/MobL family; Region: MobA_MobL; pfam03389
550537009867	HMMPfam hit to PF03389, MobA/MobL protein, score 5.5e-42
550537009868	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
550537009869	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009871	1 probable transmembrane helix predicted for SEN1983 by TMHMM2.0 at aa 10-27
550537009872	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537009873	1 probable transmembrane helix predicted for SEN1989 by TMHMM2.0 at aa 75-97
550537009874	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
550537009875	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
550537009876	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
550537009877	HMMPfam hit to PF00816, Histone-like nucleoid-structuring protein H-NS, score 2.1e-46
550537009878	2 probable transmembrane helices predicted for SEN1994 by TMHMM2.0 at aa 47-64 and 69-88
550537009879	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
550537009880	active site
550537009881	NTP binding site [chemical binding]; other site
550537009882	metal binding triad [ion binding]; metal-binding site
550537009883	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
550537009884	HMMPfam hit to PF05930, Prophage CP4-57 regulatory, score 4.9e-25
550537009885	putative protease; Region: PHA00666
550537009886	No significant database hits, carries a frame-shift mutation compared to S. gallinarum
550537009887	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
550537009888	Integrase; Region: Integrase_1; pfam12835
550537009889	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
550537009890	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537009891	Sel1 repeat; Region: Sel1; pfam08238
550537009892	Sel1-like repeats; Region: SEL1; smart00671
550537009893	HMMPfam hit to PF07661, MORN variant, score 0.88
550537009894	HMMPfam hit to PF07661, MORN variant, score 3
550537009895	HMMPfam hit to PF07661, MORN variant, score 3.3
550537009896	HMMPfam hit to PF07661, MORN variant, score 1.4
550537009897	HMMPfam hit to PF07661, MORN variant, score 0.06
550537009898	HMMPfam hit to PF07661, MORN variant, score 1.8
550537009899	HMMPfam hit to PF07661, MORN variant, score 0.0023
550537009900	HMMPfam hit to PF07661, MORN variant, score 20
550537009901	HMMPfam hit to PF07661, MORN variant, score 0.36
550537009902	HMMPfam hit to PF07661, MORN variant, score 2.5
550537009903	HMMPfam hit to PF07661, MORN variant, score 0.18
550537009904	HMMPfam hit to PF07661, MORN variant, score 2.9
550537009905	HMMPfam hit to PF07661, MORN variant, score 3.1
550537009906	HMMPfam hit to PF07661, MORN variant, score 3.7
550537009907	HMMPfam hit to PF08238, Sel1-like, score 4.3e-05
550537009908	HMMPfam hit to PF08238, Sel1-like, score 6e-06
550537009909	HMMPfam hit to PF08238, Sel1-like, score 1.5e-08
550537009910	HMMPfam hit to PF08238, Sel1-like, score 3.4e-07
550537009911	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
550537009913	HMMPfam hit to PF04461, Protein of unknown function DUF520, score 1.2e-20
550537009915	AMP nucleosidase; Provisional; Region: PRK08292
550537009916	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
550537009917	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
550537009918	HMMPfam hit to PF01048, Nucleoside phosphorylase, score 7.1e-98
550537009919	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
550537009920	HMMPfam hit to PF07377, Protein of unknown function DUF1493, score 5.6e-77
550537009921	MATE family multidrug exporter; Provisional; Region: PRK10189
550537009922	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
550537009923	11 probable transmembrane helices predicted for SEN2011 by TMHMM2.0 at aa 49-71, 86-108, 128-150, 160-182, 194-216, 231-253, 266-286, 296-318, 353-375, 390-412 and 434-456
550537009924	HMMPfam hit to PF01554, Multi antimicrobial extrusion protein MatE, score 1.5e-40
550537009925	HMMPfam hit to PF01554, Multi antimicrobial extrusion protein MatE, score 1.8e-43
550537009926	L,D-transpeptidase; Provisional; Region: PRK10190
550537009927	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
550537009928	HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 1.2e-64
550537009929	1 probable transmembrane helix predicted for SEN2013 by TMHMM2.0 at aa 7-26
550537009930	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
550537009931	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
550537009932	putative dimer interface [polypeptide binding]; other site
550537009933	active site pocket [active]
550537009934	putative cataytic base [active]
550537009935	HMMPfam hit to PF02277, Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like, core, score 5.2e-179
550537009936	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009937	cobalamin synthase; Reviewed; Region: cobS; PRK00235
550537009938	HMMPfam hit to PF02654, Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase, score 3.4e-104
550537009939	5 probable transmembrane helices predicted for SEN2015 by TMHMM2.0 at aa 33-55, 59-81, 109-131, 136-158 and 185-207
550537009940	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009941	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
550537009942	homotrimer interface [polypeptide binding]; other site
550537009943	Walker A motif; other site
550537009944	GTP binding site [chemical binding]; other site
550537009945	Walker B motif; other site
550537009946	HMMPfam hit to PF02283, Cobinamide kinase/cobinamide phosphate guanyltransferase, score 5.1e-110
550537009947	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009948	cobyric acid synthase; Provisional; Region: PRK00784
550537009949	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
550537009950	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
550537009951	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
550537009952	catalytic triad [active]
550537009953	HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase, score 8.1e-73
550537009954	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase, score 1.4e-61
550537009955	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
550537009956	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
550537009957	Walker A/P-loop; other site
550537009958	ATP binding site [chemical binding]; other site
550537009959	Q-loop/lid; other site
550537009960	ABC transporter signature motif; other site
550537009961	Walker B; other site
550537009962	D-loop; other site
550537009963	H-loop/switch region; other site
550537009964	HMMPfam hit to PF00005, ABC transporter related, score 4.5e-67
550537009965	PS00211 ABC transporters family signature.
550537009966	PS00017 ATP/GTP-binding site motif A (P-loop).
550537009967	cobalt transport protein CbiQ; Provisional; Region: PRK15485
550537009968	HMMPfam hit to PF02361, Cobalt transport protein, score 3.7e-70
550537009969	4 probable transmembrane helices predicted for SEN2019 by TMHMM2.0 at aa 22-47, 62-84, 91-110 and 120-142
550537009970	cobalt transport protein CbiN; Provisional; Region: PRK02898
550537009971	2 probable transmembrane helices predicted for SEN2020 by TMHMM2.0 at aa 5-22 and 60-82
550537009972	HMMPfam hit to PF02553, Cobalt transport protein CbiN, score 6.7e-44
550537009973	cobalt transport protein CbiM; Validated; Region: PRK08319
550537009974	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
550537009975	HMMPfam hit to PF01891, Cobalamin (vitamin B12) biosynthesis CbiM, score 2e-107
550537009976	6 probable transmembrane helices predicted for SEN2021 by TMHMM2.0 at aa 36-58, 73-95, 102-124, 134-156, 169-188 and 208-230
550537009977	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
550537009978	active site
550537009979	SAM binding site [chemical binding]; other site
550537009980	homodimer interface [polypeptide binding]; other site
550537009981	HMMPfam hit to PF00590, Tetrapyrrole methylase, score 1.9e-64
550537009982	PS00840 Uroporphyrin-III C-methyltransferase signature 2.
550537009983	PS00839 Uroporphyrin-III C-methyltransferase signature 1.
550537009984	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
550537009985	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
550537009986	active site
550537009987	C-terminal domain interface [polypeptide binding]; other site
550537009988	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
550537009989	active site
550537009990	N-terminal domain interface [polypeptide binding]; other site
550537009991	HMMPfam hit to PF06180, Anaerobic cobalt chelatase, score 2.3e-169
550537009992	PS00761 Signal peptidases I signature 3.
550537009993	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537009994	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
550537009995	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
550537009996	HMMPfam hit to PF02571, Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase, score 2.5e-36
550537009997	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
550537009998	active site
550537009999	SAM binding site [chemical binding]; other site
550537010000	homodimer interface [polypeptide binding]; other site
550537010001	HMMPfam hit to PF00590, Tetrapyrrole methylase, score 5.6e-77
550537010002	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
550537010003	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
550537010004	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
550537010005	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
550537010006	HMMPfam hit to PF01890, Cobalamin (vitamin B12) biosynthesis CbiG, core, score 3.2e-163
550537010007	1 probable transmembrane helix predicted for SEN2026 by TMHMM2.0 at aa 58-80
550537010008	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
550537010009	active site
550537010010	SAM binding site [chemical binding]; other site
550537010011	homodimer interface [polypeptide binding]; other site
550537010012	HMMPfam hit to PF00590, Tetrapyrrole methylase, score 3.9e-84
550537010013	PS00840 Uroporphyrin-III C-methyltransferase signature 2.
550537010014	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010015	PS00839 Uroporphyrin-III C-methyltransferase signature 1.
550537010016	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
550537010017	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537010018	S-adenosylmethionine binding site [chemical binding]; other site
550537010019	PS00012 Phosphopantetheine attachment site.
550537010020	HMMPfam hit to PF08242, Methyltransferase type 12, score 2e-09
550537010021	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
550537010022	active site
550537010023	putative homodimer interface [polypeptide binding]; other site
550537010024	SAM binding site [chemical binding]; other site
550537010025	HMMPfam hit to PF00590, Tetrapyrrole methylase, score 5.9e-60
550537010026	PS00215 Mitochondrial energy transfer proteins signature.
550537010027	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
550537010028	HMMPfam hit to PF01888, Cobalamin (vitamin B12) biosynthesis CbiD, score 5.7e-185
550537010029	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
550537010030	Precorrin-8X methylmutase; Region: CbiC; pfam02570
550537010031	HMMPfam hit to PF02570, Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core, score 2.3e-38
550537010032	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
550537010033	HMMPfam hit to PF03186, Cobalamin (vitamin B12) biosynthesis CbiB, score 9e-187
550537010034	5 probable transmembrane helices predicted for SEN2032 by TMHMM2.0 at aa 52-74, 79-101, 155-177, 207-229 and 296-318
550537010035	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
550537010036	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
550537010037	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
550537010038	catalytic triad [active]
550537010039	HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase, score 8e-52
550537010040	HMMPfam hit to PF01656, Cobyrinic acid a,c-diamide synthase, score 2.4e-48
550537010041	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010042	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
550537010043	Sensory domain found in PocR; Region: PocR; pfam10114
550537010044	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537010045	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537010046	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537010047	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 4.8e-15
550537010048	PS00041 Bacterial regulatory proteins, araC family signature.
550537010049	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 9.6e-14
550537010050	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
550537010051	amphipathic channel; other site
550537010052	Asn-Pro-Ala signature motifs; other site
550537010053	7 probable transmembrane helices predicted for SEN2035 by TMHMM2.0
550537010054	HMMPfam hit to PF00230, Major intrinsic protein, score 1.7e-92
550537010055	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010056	PS00221 MIP family signature.
550537010057	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
550537010058	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
550537010059	Hexamer interface [polypeptide binding]; other site
550537010060	Putative hexagonal pore residue; other site
550537010061	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 1e-40
550537010062	PS01139 Bacterial microcompartiments proteins signature.
550537010063	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutL; COG4816
550537010064	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
550537010065	putative hexamer interface [polypeptide binding]; other site
550537010066	putative hexagonal pore; other site
550537010067	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
550537010068	putative hexamer interface [polypeptide binding]; other site
550537010069	putative hexagonal pore; other site
550537010070	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 2.2e-18
550537010071	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 3.1e-19
550537010072	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
550537010073	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
550537010074	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
550537010075	alpha-beta subunit interface [polypeptide binding]; other site
550537010076	alpha-gamma subunit interface [polypeptide binding]; other site
550537010077	active site
550537010078	substrate and K+ binding site; other site
550537010079	K+ binding site [ion binding]; other site
550537010080	cobalamin binding site [chemical binding]; other site
550537010081	HMMPfam hit to PF02286, Dehydratase, large subunit, score 0
550537010082	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010083	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
550537010084	HMMPfam hit to PF02288, Dehydratase, medium subunit, score 5.5e-127
550537010085	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
550537010086	HMMPfam hit to PF02287, Dehydratase, small subunit, score 1.4e-108
550537010087	Cell division protein FtsA; Region: FtsA; cl17206
550537010088	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
550537010089	HMMPfam hit to PF08841, Diol/glycerol dehydratase reactivating factor, large subunit, score 0
550537010090	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
550537010091	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
550537010092	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
550537010093	Hexamer interface [polypeptide binding]; other site
550537010094	Putative hexagonal pore residue; other site
550537010095	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 2.2e-41
550537010096	PS01139 Bacterial microcompartiments proteins signature.
550537010097	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
550537010098	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
550537010099	putative hexamer interface [polypeptide binding]; other site
550537010100	putative hexagonal pore; other site
550537010101	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 2.5e-31
550537010102	1 probable transmembrane helix predicted for SEN2044 by TMHMM2.0 at aa 12-31
550537010103	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
550537010104	Propanediol utilisation protein PduL; Region: PduL; pfam06130
550537010105	Propanediol utilisation protein PduL; Region: PduL; pfam06130
550537010106	HMMPfam hit to PF06130, Propanediol utilization protein, score 9.9e-46
550537010107	HMMPfam hit to PF06130, Propanediol utilization protein, score 5.7e-36
550537010108	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
550537010109	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
550537010110	Hexamer/Pentamer interface [polypeptide binding]; other site
550537010111	central pore; other site
550537010112	HMMPfam hit to PF03319, Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, score 2.2e-45
550537010113	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
550537010114	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
550537010115	HMMPfam hit to PF01923, Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, score 3.9e-94
550537010116	HMMPfam hit to PF03928, Protein of unknown function DUF336, score 9.1e-55
550537010117	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
550537010118	putative catalytic cysteine [active]
550537010119	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 1.1e-08
550537010120	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
550537010121	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
550537010122	putative active site [active]
550537010123	metal binding site [ion binding]; metal-binding site
550537010124	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 3e-94
550537010125	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537010126	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
550537010127	SLBB domain; Region: SLBB; pfam10531
550537010128	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
550537010129	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
550537010130	HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit, score 2.8e-16
550537010131	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0097
550537010132	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537010133	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
550537010134	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
550537010135	putative hexamer interface [polypeptide binding]; other site
550537010136	putative hexagonal pore; other site
550537010137	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
550537010138	putative hexamer interface [polypeptide binding]; other site
550537010139	putative hexagonal pore; other site
550537010140	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 4.5e-28
550537010141	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 5.4e-32
550537010142	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
550537010143	putative hexamer interface [polypeptide binding]; other site
550537010144	putative hexagonal pore; other site
550537010145	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 4e-24
550537010146	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
550537010147	G3 box; other site
550537010148	Switch II region; other site
550537010149	GTP/Mg2+ binding site [chemical binding]; other site
550537010150	G4 box; other site
550537010151	G5 box; other site
550537010152	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010153	propionate kinase; Reviewed; Region: PRK12397
550537010154	propionate/acetate kinase; Provisional; Region: PRK12379
550537010155	HMMPfam hit to PF00871, Acetate and butyrate kinase, score 3.1e-198
550537010156	PS01075 Acetate and butyrate kinases family signature 1.
550537010157	PS01076 Acetate and butyrate kinases family signature 2.
550537010158	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
550537010159	HMMPfam hit to PF00288, GHMP kinase, score 4.8e-10
550537010160	HMMPfam hit to PF08544, GHMP kinase, C-terminal, score 4e-05
550537010161	hypothetical protein; Provisional; Region: PRK05423
550537010162	HMMPfam hit to PF04363, Protein of unknown function DUF496, score 3.9e-69
550537010163	Predicted membrane protein [Function unknown]; Region: COG1289
550537010164	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
550537010165	6 probable transmembrane helices predicted for SEN2058 by TMHMM2.0 at aa 20-42, 47-66, 73-92, 96-113, 118-135 and 140-162
550537010166	DNA gyrase inhibitor; Provisional; Region: PRK10016
550537010167	HMMPfam hit to PF06445, Bacterial transcription activator, effector binding, score 7.3e-35
550537010168	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
550537010169	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
550537010170	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
550537010171	HMMPfam hit to PF07943, Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal, score 5.5e-34
550537010172	HMMPfam hit to PF00768, Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, score 8.8e-146
550537010173	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
550537010174	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
550537010175	HMMPfam hit to PF01292, Cytochrome B561, bacterial, score 0.00034
550537010176	5 probable transmembrane helices predicted for SEN2061 by TMHMM2.0 at aa 15-37, 66-88, 93-115, 169-191 and 201-223
550537010177	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
550537010178	4Fe-4S binding domain; Region: Fer4; cl02805
550537010179	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 6.1e-07
550537010180	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537010181	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0037
550537010182	thiosulfate reductase PhsA; Provisional; Region: PRK15488
550537010183	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
550537010184	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
550537010185	putative [Fe4-S4] binding site [ion binding]; other site
550537010186	putative molybdopterin cofactor binding site [chemical binding]; other site
550537010187	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537010188	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
550537010189	putative molybdopterin cofactor binding site; other site
550537010190	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 5.5e-26
550537010191	PS00932 Prokaryotic molybdopterin oxidoreductases signature 3.
550537010192	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 2e-145
550537010193	PS00490 Prokaryotic molybdopterin oxidoreductases signature 2.
550537010194	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 5e-16
550537010195	PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
550537010196	E3 ubiquitin-protein ligase SopA; Provisional; Region: PRK15377
550537010197	SopA-like central domain; Region: SopA; pfam13981
550537010198	SopA-like catalytic domain; Region: SopA_C; pfam13979
550537010199	exonuclease I; Provisional; Region: sbcB; PRK11779
550537010200	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
550537010201	active site
550537010202	catalytic site [active]
550537010203	substrate binding site [chemical binding]; other site
550537010204	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
550537010205	HMMPfam hit to PF00929, Exonuclease, RNase T and DNA polymerase III, score 2.3e-37
550537010206	HMMPfam hit to PF08411, Exonuclease C-terminal, score 9.1e-174
550537010207	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
550537010208	12 probable transmembrane helices predicted for SEN2067 by TMHMM2.0 at aa 20-38, 53-75, 96-118, 133-151, 158-180, 200-219, 240-262, 289-311, 342-364, 368-385, 398-417 and 422-439
550537010209	HMMPfam hit to PF00324, Amino acid permease-associated region, score 2.1e-16
550537010210	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537010211	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
550537010212	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537010213	dimerization interface [polypeptide binding]; other site
550537010214	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.1e-27
550537010215	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 6.9e-16
550537010216	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
550537010217	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
550537010218	putative NAD(P) binding site [chemical binding]; other site
550537010219	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010220	HMMPfam hit to PF03446, 6-phosphogluconate dehydrogenase, NAD-binding, score 1.1e-05
550537010221	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
550537010222	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
550537010223	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
550537010224	HMMPfam hit to PF01634, ATP phosphoribosyltransferase, catalytic region, score 9.6e-84
550537010225	PS01316 ATP phosphoribosyltransferase signature.
550537010226	HMMPfam hit to PF08029, Histidine biosynthesis HisG, C-terminal, score 2.3e-38
550537010227	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
550537010228	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
550537010229	NAD binding site [chemical binding]; other site
550537010230	dimerization interface [polypeptide binding]; other site
550537010231	product binding site; other site
550537010232	substrate binding site [chemical binding]; other site
550537010233	zinc binding site [ion binding]; other site
550537010234	catalytic residues [active]
550537010235	HMMPfam hit to PF00815, Histidinol dehydrogenase, score 1.2e-271
550537010236	PS00611 Histidinol dehydrogenase signature.
550537010237	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
550537010238	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537010239	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537010240	homodimer interface [polypeptide binding]; other site
550537010241	catalytic residue [active]
550537010242	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 1.4e-86
550537010243	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
550537010244	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
550537010245	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537010246	active site
550537010247	motif I; other site
550537010248	motif II; other site
550537010249	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
550537010250	putative active site pocket [active]
550537010251	4-fold oligomerization interface [polypeptide binding]; other site
550537010252	metal binding residues [ion binding]; metal-binding site
550537010253	3-fold/trimer interface [polypeptide binding]; other site
550537010254	HMMPfam hit to PF08645, Polynucleotide kinase 3 phosphatase, central region, score 0.00068
550537010255	HMMPfam hit to PF00475, Imidazole glycerol-phosphate dehydratase, score 3.6e-107
550537010256	PS00954 Imidazoleglycerol-phosphate dehydratase signature 1.
550537010257	PS00955 Imidazoleglycerol-phosphate dehydratase signature 2.
550537010258	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
550537010259	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
550537010260	putative active site [active]
550537010261	oxyanion strand; other site
550537010262	catalytic triad [active]
550537010263	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 5e-43
550537010264	PS00442 Glutamine amidotransferases class-I active site.
550537010265	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
550537010266	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
550537010267	catalytic residues [active]
550537010268	HMMPfam hit to PF00977, Histidine biosynthesis, score 1.1e-107
550537010269	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
550537010270	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
550537010271	substrate binding site [chemical binding]; other site
550537010272	glutamase interaction surface [polypeptide binding]; other site
550537010273	HMMPfam hit to PF00977, Histidine biosynthesis, score 2.7e-118
550537010274	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
550537010275	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
550537010276	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
550537010277	metal binding site [ion binding]; metal-binding site
550537010278	PS00430 TonB-dependent receptor proteins signature 1.
550537010279	HMMPfam hit to PF01502, Phosphoribosyl-AMP cyclohydrolase, score 5.4e-43
550537010280	HMMPfam hit to PF01503, Phosphoribosyl-ATP pyrophosphohydrolase, score 1.2e-47
550537010281	chain length determinant protein WzzB; Provisional; Region: PRK15471
550537010282	Chain length determinant protein; Region: Wzz; cl15801
550537010283	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
550537010284	2 probable transmembrane helices predicted for SEN2078 by TMHMM2.0 at aa 33-52 and 296-315
550537010285	HMMPfam hit to PF02706, Lipopolysaccharide biosynthesis, score 6.5e-32
550537010286	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
550537010287	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
550537010288	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
550537010289	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
550537010290	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, C-terminal, score 6.2e-05
550537010291	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, dimerisation, score 1.9e-36
550537010292	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, N-terminal, score 2.3e-41
550537010293	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
550537010294	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
550537010295	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
550537010296	HMMPfam hit to PF00393, 6-phosphogluconate dehydrogenase, C-terminal, score 2e-257
550537010297	PS00461 6-phosphogluconate dehydrogenase signature.
550537010298	HMMPfam hit to PF03446, 6-phosphogluconate dehydrogenase, NAD-binding, score 2.1e-93
550537010299	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
550537010300	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
550537010301	Bacterial sugar transferase; Region: Bac_transf; pfam02397
550537010302	HMMPfam hit to PF02397, Bacterial sugar transferase, score 1.4e-143
550537010303	5 probable transmembrane helices predicted for SEN2081 by TMHMM2.0 at aa 15-37, 57-74, 89-108, 115-134 and 282-304
550537010304	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010305	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
550537010306	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
550537010307	active site
550537010308	substrate binding site [chemical binding]; other site
550537010309	metal binding site [ion binding]; metal-binding site
550537010310	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase C-terminal, score 3.9e-26
550537010311	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III, score 3.1e-39
550537010312	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II, score 2e-38
550537010313	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, score 8.1e-39
550537010314	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
550537010315	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
550537010316	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
550537010317	Substrate binding site; other site
550537010318	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
550537010319	HMMPfam hit to PF01050, Mannose-6-phosphate isomerase, type II, C-terminal, score 4e-124
550537010320	HMMPfam hit to PF00483, Nucleotidyl transferase, score 5.8e-145
550537010321	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
550537010322	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
550537010323	active site
550537010324	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
550537010325	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 8.4e-28
550537010326	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
550537010327	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
550537010328	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 8.4e-44
550537010329	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
550537010330	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
550537010331	active site
550537010332	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010333	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 6.7e-29
550537010334	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
550537010335	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
550537010336	12 probable transmembrane helices predicted for SEN2085B by TMHMM2.0 at aa 20-39, 54-76, 96-115, 139-161, 168-190, 200-222, 235-257, 277-299, 311-333, 348-367, 380-402 and 406-428
550537010337	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
550537010338	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
550537010339	NAD binding site [chemical binding]; other site
550537010340	homotetramer interface [polypeptide binding]; other site
550537010341	homodimer interface [polypeptide binding]; other site
550537010342	active site
550537010343	substrate binding site [chemical binding]; other site
550537010344	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 5.2e-49
550537010345	1 probable transmembrane helix predicted for SEN2085C by TMHMM2.0 at aa 7-29
550537010346	Signal peptide predicted for SEN2085C by SignalP 2.0 HMM (Signal peptide probability 0.969) with cleavage site probability 0.690 between residues 24 and 25
550537010347	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
550537010348	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
550537010349	NAD(P) binding site [chemical binding]; other site
550537010350	active site
550537010351	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 1e-35
550537010352	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
550537010353	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
550537010354	inhibitor-cofactor binding pocket; inhibition site
550537010355	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537010356	catalytic residue [active]
550537010357	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 3.1e-173
550537010358	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
550537010359	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
550537010360	NAD binding site [chemical binding]; other site
550537010361	homotetramer interface [polypeptide binding]; other site
550537010362	homodimer interface [polypeptide binding]; other site
550537010363	substrate binding site [chemical binding]; other site
550537010364	active site
550537010365	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 5.4e-18
550537010366	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
550537010367	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
550537010368	substrate binding site; other site
550537010369	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.2e-10
550537010370	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
550537010371	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
550537010372	catalytic loop [active]
550537010373	iron binding site [ion binding]; other site
550537010374	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
550537010375	FAD binding pocket [chemical binding]; other site
550537010376	FAD binding motif [chemical binding]; other site
550537010377	phosphate binding motif [ion binding]; other site
550537010378	beta-alpha-beta structure motif; other site
550537010379	NAD binding pocket [chemical binding]; other site
550537010380	HMMPfam hit to PF00175, Oxidoreductase FAD/NAD(P)-binding, score 3.6e-37
550537010381	HMMPfam hit to PF00970, Oxidoreductase FAD-binding region, score 3.2e-31
550537010382	HMMPfam hit to PF00111, Ferredoxin, score 6.7e-17
550537010383	PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature.
550537010384	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
550537010385	HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase related, score 1.7e-127
550537010386	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
550537010387	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
550537010388	substrate binding site; other site
550537010389	tetramer interface; other site
550537010390	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.5e-117
550537010391	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
550537010392	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
550537010393	NADP binding site [chemical binding]; other site
550537010394	active site
550537010395	putative substrate binding site [chemical binding]; other site
550537010396	HMMPfam hit to PF04321, dTDP-4-dehydrorhamnose reductase, score 2.6e-166
550537010397	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
550537010398	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
550537010399	NAD binding site [chemical binding]; other site
550537010400	substrate binding site [chemical binding]; other site
550537010401	homodimer interface [polypeptide binding]; other site
550537010402	active site
550537010403	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 3.1e-97
550537010404	PS00061 Short-chain dehydrogenases/reductases family signature.
550537010405	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
550537010406	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
550537010407	active site
550537010408	tetramer interface; other site
550537010409	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.7e-11
550537010410	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
550537010411	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
550537010412	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
550537010413	putative ADP-binding pocket [chemical binding]; other site
550537010414	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 1.9e-46
550537010415	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
550537010416	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
550537010417	HMMPfam hit to PF04230, Polysaccharide pyruvyl transferase, score 1.4e-159
550537010418	colanic acid exporter; Provisional; Region: PRK10459
550537010419	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
550537010420	10 probable transmembrane helices predicted for SEN2098 by TMHMM2.0 at aa 13-35, 45-67, 80-102, 165-187, 286-308, 323-340, 361-383, 387-409, 416-435 and 450-472
550537010421	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 1.6e-71
550537010422	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
550537010423	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
550537010424	HMMPfam hit to PF02397, Bacterial sugar transferase, score 7.5e-44
550537010425	5 probable transmembrane helices predicted for SEN2099 by TMHMM2.0 at aa 13-35, 45-64, 84-101, 111-130 and 279-300
550537010426	phosphomannomutase CpsG; Provisional; Region: PRK15414
550537010427	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
550537010428	active site
550537010429	substrate binding site [chemical binding]; other site
550537010430	metal binding site [ion binding]; metal-binding site
550537010431	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase C-terminal, score 4.4e-30
550537010432	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III, score 4.5e-54
550537010433	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II, score 2.7e-55
550537010434	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, score 1.9e-51
550537010435	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
550537010436	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
550537010437	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
550537010438	Substrate binding site; other site
550537010439	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
550537010440	HMMPfam hit to PF01050, Mannose-6-phosphate isomerase, type II, C-terminal, score 4.9e-134
550537010441	HMMPfam hit to PF00483, Nucleotidyl transferase, score 7.8e-139
550537010442	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
550537010443	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
550537010444	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 1.6e-18
550537010445	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
550537010446	active site
550537010447	GDP-Mannose binding site [chemical binding]; other site
550537010448	dimer interface [polypeptide binding]; other site
550537010449	modified nudix motif
550537010450	metal binding site [ion binding]; metal-binding site
550537010451	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 3e-24
550537010452	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
550537010453	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
550537010454	NADP binding site [chemical binding]; other site
550537010455	active site
550537010456	putative substrate binding site [chemical binding]; other site
550537010457	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 1.5e-92
550537010458	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
550537010459	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
550537010460	NADP-binding site; other site
550537010461	homotetramer interface [polypeptide binding]; other site
550537010462	substrate binding site [chemical binding]; other site
550537010463	homodimer interface [polypeptide binding]; other site
550537010464	active site
550537010465	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 1.1e-110
550537010466	PS00061 Short-chain dehydrogenases/reductases family signature.
550537010467	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
550537010468	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
550537010469	putative trimer interface [polypeptide binding]; other site
550537010470	putative active site [active]
550537010471	putative substrate binding site [chemical binding]; other site
550537010472	putative CoA binding site [chemical binding]; other site
550537010473	PS00101 Hexapeptide-repeat containing-transferases signature.
550537010474	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.16
550537010475	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1.1e+02
550537010476	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.15
550537010477	putative glycosyl transferase; Provisional; Region: PRK10063
550537010478	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
550537010479	metal-binding site
550537010480	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 2.9e-19
550537010481	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
550537010482	12 probable transmembrane helices predicted for SEN2108 by TMHMM2.0 at aa 7-25, 30-47, 54-76, 81-103, 116-138, 143-165, 172-189, 204-226, 246-268, 283-305, 326-348 and 368-390
550537010483	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
550537010484	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
550537010485	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
550537010486	putative acyl transferase; Provisional; Region: PRK10191
550537010487	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
550537010488	trimer interface [polypeptide binding]; other site
550537010489	active site
550537010490	substrate binding site [chemical binding]; other site
550537010491	CoA binding site [chemical binding]; other site
550537010492	PS00101 Hexapeptide-repeat containing-transferases signature.
550537010493	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.17
550537010494	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 29
550537010495	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1.1e+02
550537010496	putative glycosyl transferase; Provisional; Region: PRK10018
550537010497	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
550537010498	active site
550537010499	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 1.5e-30
550537010500	tyrosine kinase; Provisional; Region: PRK11519
550537010501	Chain length determinant protein; Region: Wzz; pfam02706
550537010502	Chain length determinant protein; Region: Wzz; cl15801
550537010503	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
550537010504	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
550537010505	2 probable transmembrane helices predicted for SEN2112 by TMHMM2.0 at aa 31-53 and 426-448
550537010506	HMMPfam hit to PF02706, Lipopolysaccharide biosynthesis, score 3.9e-90
550537010507	Low molecular weight phosphatase family; Region: LMWPc; cd00115
550537010508	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
550537010509	active site
550537010510	HMMPfam hit to PF01451, Protein-tyrosine phosphatase, low molecular weight, score 1.4e-60
550537010511	polysaccharide export protein Wza; Provisional; Region: PRK15078
550537010512	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
550537010513	HMMPfam hit to PF02563, Polysaccharide export protein, score 9.7e-68
550537010514	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
550537010515	FOG: CBS domain [General function prediction only]; Region: COG0517
550537010516	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
550537010517	Transporter associated domain; Region: CorC_HlyC; smart01091
550537010518	HMMPfam hit to PF03741, Integral membrane protein TerC, score 4.2e-35
550537010519	7 probable transmembrane helices predicted for SEN2115 by TMHMM2.0 at aa 13-35, 48-70, 80-99, 126-148, 153-172, 185-207 and 212-234
550537010520	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 3.5e-24
550537010521	HMMPfam hit to PF03471, Transporter-associated region, score 5.9e-23
550537010522	putative assembly protein; Provisional; Region: PRK10833
550537010523	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
550537010524	HMMPfam hit to PF05170, AsmA, score 7e-138
550537010525	1 probable transmembrane helix predicted for SEN2116 by TMHMM2.0 at aa 7-26
550537010526	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
550537010527	trimer interface [polypeptide binding]; other site
550537010528	active site
550537010529	HMMPfam hit to PF00692, DeoxyUTP pyrophosphatase, score 0.00056
550537010530	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
550537010531	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
550537010532	ATP-binding site [chemical binding]; other site
550537010533	Sugar specificity; other site
550537010534	Pyrimidine base specificity; other site
550537010535	HMMPfam hit to PF00485, Phosphoribulokinase/uridine kinase, score 6.3e-52
550537010536	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010537	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
550537010538	PAS domain S-box; Region: sensory_box; TIGR00229
550537010539	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537010540	putative active site [active]
550537010541	heme pocket [chemical binding]; other site
550537010542	PAS domain S-box; Region: sensory_box; TIGR00229
550537010543	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537010544	putative active site [active]
550537010545	heme pocket [chemical binding]; other site
550537010546	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
550537010547	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537010548	metal binding site [ion binding]; metal-binding site
550537010549	active site
550537010550	I-site; other site
550537010551	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537010552	10 probable transmembrane helices predicted for SEN2119 by TMHMM2.0 at aa 15-37, 64-86, 90-112, 124-146, 156-177, 189-208, 212-229, 236-258, 268-290 and 310-327
550537010553	HMMPfam hit to PF05231, MASE1, score 1.2e-59
550537010554	HMMPfam hit to PF08447, PAS fold-3, score 1.8e-07
550537010555	HMMPfam hit to PF08448, PAS fold-4, score 3.7e-11
550537010556	HMMPfam hit to PF00990, GGDEF, score 1.1e-63
550537010557	HMMPfam hit to PF00563, EAL, score 1.8e-08
550537010558	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
550537010559	AlkA N-terminal domain; Region: AlkA_N; pfam06029
550537010560	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
550537010561	minor groove reading motif; other site
550537010562	helix-hairpin-helix signature motif; other site
550537010563	substrate binding pocket [chemical binding]; other site
550537010564	active site
550537010565	HMMPfam hit to PF00730, HhH-GPD, score 4e-16
550537010566	PS00516 Alkylbase DNA glycosidases alkA family signature.
550537010567	HMMPfam hit to PF06029, AlkA, N-terminal, score 7.9e-65
550537010568	putative chaperone; Provisional; Region: PRK11678
550537010569	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
550537010570	nucleotide binding site [chemical binding]; other site
550537010571	putative NEF/HSP70 interaction site [polypeptide binding]; other site
550537010572	SBD interface [polypeptide binding]; other site
550537010573	PS00329 Heat shock hsp70 proteins family signature 2.
550537010574	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
550537010575	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537010576	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537010577	1 probable transmembrane helix predicted for SEN2122 by TMHMM2.0 at aa 7-26
550537010578	HMMPfam hit to PF00529, Secretion protein HlyD, score 6.2e-25
550537010579	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
550537010580	Protein export membrane protein; Region: SecD_SecF; cl14618
550537010581	HMMPfam hit to PF00873, Acriflavin resistance protein, score 0
550537010582	11 probable transmembrane helices predicted for SEN2123 by TMHMM2.0 at aa 15-37, 345-362, 367-389, 396-418, 438-460, 472-494, 535-557, 867-889, 909-931, 968-990 and 1000-1022
550537010583	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
550537010584	HMMPfam hit to PF00873, Acriflavin resistance protein, score 0
550537010585	10 probable transmembrane helices predicted for SEN2124 by TMHMM2.0 at aa 7-29, 336-353, 360-382, 434-456, 463-485, 525-547, 853-875, 895-917, 948-970 and 985-1007
550537010586	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010587	putative transporter; Provisional; Region: PRK10504
550537010588	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537010589	putative substrate translocation pore; other site
550537010590	13 probable transmembrane helices predicted for SEN2125 by TMHMM2.0 at aa 12-34, 47-69, 76-98, 102-124, 136-158, 163-185, 197-214, 224-243, 255-277, 287-309, 330-352, 395-417 and 430-452
550537010591	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.4e-53
550537010592	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
550537010593	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537010594	dimerization interface [polypeptide binding]; other site
550537010595	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537010596	dimer interface [polypeptide binding]; other site
550537010597	phosphorylation site [posttranslational modification]
550537010598	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537010599	ATP binding site [chemical binding]; other site
550537010600	Mg2+ binding site [ion binding]; other site
550537010601	G-X-G motif; other site
550537010602	2 probable transmembrane helices predicted for SEN2126 by TMHMM2.0 at aa 13-35 and 168-190
550537010603	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 5.8e-20
550537010604	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.6e-16
550537010605	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.4e-35
550537010606	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
550537010607	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537010608	active site
550537010609	phosphorylation site [posttranslational modification]
550537010610	intermolecular recognition site; other site
550537010611	dimerization interface [polypeptide binding]; other site
550537010612	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537010613	DNA binding site [nucleotide binding]
550537010614	HMMPfam hit to PF00072, Response regulator receiver, score 2.2e-30
550537010615	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 1.6e-22
550537010616	PS00294 Prenyl group binding site (CAAX box).
550537010617	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
550537010618	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
550537010619	putative protease; Provisional; Region: PRK15452
550537010620	Peptidase family U32; Region: Peptidase_U32; pfam01136
550537010621	HMMPfam hit to PF01136, Peptidase U32, score 2.7e-150
550537010622	PS01276 Peptidase family U32 signature.
550537010623	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
550537010624	HMMPfam hit to PF05932, Tir chaperone, score 3.3e-38
550537010625	2 probable transmembrane helices predicted for SEN2134 by TMHMM2.0 at aa 42-64 and 79-101
550537010626	1 probable transmembrane helix predicted for SEN2135 by TMHMM2.0 at aa 5-24
550537010628	HMMPfam hit to PF00781, Diacylglycerol kinase, catalytic region, score 1.5e-33
550537010629	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
550537010630	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
550537010631	putative active site; other site
550537010632	catalytic residue [active]
550537010633	HMMPfam hit to PF01791, Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase, score 3.7e-85
550537010634	nucleoside transporter; Region: 2A0110; TIGR00889
550537010635	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537010636	putative substrate translocation pore; other site
550537010637	HMMPfam hit to PF03825, Nucleoside:H+ symporter, score 8.8e-281
550537010638	12 probable transmembrane helices predicted for SEN2138 by TMHMM2.0 at aa 7-29, 39-61, 70-87, 97-119, 132-154, 159-181, 211-233, 243-265, 274-293, 297-319, 339-358 and 378-400
550537010639	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010640	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
550537010641	HMMPfam hit to PF03747, ADP-ribosylation/Crystallin J1, score 8.7e-99
550537010642	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537010643	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
550537010644	substrate binding site [chemical binding]; other site
550537010645	ATP binding site [chemical binding]; other site
550537010646	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 7.4e-43
550537010647	PS00583 pfkB family of carbohydrate kinases signature 1.
550537010648	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010649	PS00584 pfkB family of carbohydrate kinases signature 2.
550537010650	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
550537010651	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537010652	DNA-binding site [nucleotide binding]; DNA binding site
550537010653	UTRA domain; Region: UTRA; pfam07702
550537010654	HMMPfam hit to PF07702, UbiC transcription regulator-associated, score 6.9e-45
550537010655	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 2.9e-18
550537010656	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
550537010657	dimer interface [polypeptide binding]; other site
550537010658	substrate binding site [chemical binding]; other site
550537010659	ATP binding site [chemical binding]; other site
550537010660	HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase type-1, score 2.1e-144
550537010661	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
550537010662	substrate binding site [chemical binding]; other site
550537010663	multimerization interface [polypeptide binding]; other site
550537010664	ATP binding site [chemical binding]; other site
550537010665	HMMPfam hit to PF02110, Hydroxyethylthiazole kinase, score 8.7e-153
550537010666	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010667	Predicted integral membrane protein [Function unknown]; Region: COG5455
550537010668	fimbrial operon peg
550537010669	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
550537010670	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
550537010671	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
550537010672	PapC N-terminal domain; Region: PapC_N; pfam13954
550537010673	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537010674	PapC C-terminal domain; Region: PapC_C; pfam13953
550537010675	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 9.5e-284
550537010676	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
550537010677	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537010678	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 1.1e-07
550537010679	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 2.1e-60
550537010680	PS00635 Gram-negative pili assembly chaperone signature.
550537010681	1 probable transmembrane helix predicted for SEN2145A by TMHMM2.0 at aa 26-48
550537010682	Signal peptide predicted for SEN2145A by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.674 between residues 41 and 42
550537010683	fimbrial chaperone protein; Provisional; Region: PRK15220
550537010684	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.0014
550537010685	PS00237 G-protein coupled receptors signature.
550537010686	Signal peptide predicted for SEN2145B by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 35 and 36
550537010687	1 probable transmembrane helix predicted for SEN2145B by TMHMM2.0 at aa 13-35
550537010688	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
550537010689	antiporter inner membrane protein; Provisional; Region: PRK11670
550537010690	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
550537010691	Walker A motif; other site
550537010692	PS01215 Mrp family signature.
550537010693	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010694	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
550537010695	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
550537010696	active site
550537010697	HIGH motif; other site
550537010698	KMSKS motif; other site
550537010699	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
550537010700	tRNA binding surface [nucleotide binding]; other site
550537010701	anticodon binding site; other site
550537010702	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
550537010703	dimer interface [polypeptide binding]; other site
550537010704	putative tRNA-binding site [nucleotide binding]; other site
550537010705	HMMPfam hit to PF09334, Aminoacyl-tRNA synthetase, class I (M), score 2.7e-235
550537010706	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537010707	HMMPfam hit to PF01588, tRNA-binding region, score 3.9e-41
550537010708	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
550537010709	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010710	HMMPfam hit to PF06998, Protein of unknown function DUF1307, score 1.4e-75
550537010711	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
550537010712	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010713	HMMPfam hit to PF06998, Protein of unknown function DUF1307, score 7.1e-80
550537010714	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
550537010715	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
550537010716	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
550537010717	HMMPfam hit to PF07308, Protein of unknown function DUF1456, score 1.7e-32
550537010718	HMMPfam hit to PF07308, Protein of unknown function DUF1456, score 1.5e-34
550537010719	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
550537010720	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537010721	active site
550537010722	phosphorylation site [posttranslational modification]
550537010723	intermolecular recognition site; other site
550537010724	dimerization interface [polypeptide binding]; other site
550537010725	LytTr DNA-binding domain; Region: LytTR; pfam04397
550537010726	HMMPfam hit to PF04397, LytTr DNA-binding region, score 2.1e-27
550537010727	HMMPfam hit to PF00072, Response regulator receiver, score 3.7e-41
550537010728	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
550537010729	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
550537010730	GAF domain; Region: GAF; pfam01590
550537010731	Histidine kinase; Region: His_kinase; pfam06580
550537010732	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537010733	ATP binding site [chemical binding]; other site
550537010734	Mg2+ binding site [ion binding]; other site
550537010735	G-X-G motif; other site
550537010736	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2.8e-15
550537010737	HMMPfam hit to PF06580, Histidine kinase internal region, score 5e-43
550537010738	HMMPfam hit to PF01590, GAF, score 0.00055
550537010739	6 probable transmembrane helices predicted for SEN2153 by TMHMM2.0 at aa 4-23, 44-63, 73-95, 107-129, 139-161 and 168-190
550537010740	HMMPfam hit to PF07694, 5TM Receptors of the LytS-YhcK type, transmembrane region, score 4.7e-41
550537010741	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010742	transcriptional regulator MirA; Provisional; Region: PRK15043
550537010743	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
550537010744	DNA binding residues [nucleotide binding]
550537010745	HMMPfam hit to PF00376, Bacterial regulatory protein, MerR, score 4.9e-12
550537010746	PS00552 Bacterial regulatory proteins, merR family signature.
550537010747	hypothetical protein; Provisional; Region: PRK13681
550537010748	1 probable transmembrane helix predicted for SEN2155 by TMHMM2.0 at aa 7-29
550537010749	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
550537010750	putative PBP binding loops; other site
550537010751	ABC-ATPase subunit interface; other site
550537010752	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1e-28
550537010753	6 probable transmembrane helices predicted for SEN2156 by TMHMM2.0 at aa 7-29, 54-76, 89-111, 121-143, 164-186 and 201-223
550537010754	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
550537010755	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
550537010756	Walker A/P-loop; other site
550537010757	ATP binding site [chemical binding]; other site
550537010758	Q-loop/lid; other site
550537010759	ABC transporter signature motif; other site
550537010760	Walker B; other site
550537010761	D-loop; other site
550537010762	H-loop/switch region; other site
550537010763	CBS domain; Region: CBS; pfam00571
550537010764	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 3.1e-05
550537010765	HMMPfam hit to PF00005, ABC transporter related, score 4.2e-59
550537010766	PS00211 ABC transporters family signature.
550537010767	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010768	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537010769	dimer interface [polypeptide binding]; other site
550537010770	conserved gate region; other site
550537010771	ABC-ATPase subunit interface; other site
550537010772	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 7.6e-28
550537010773	10 probable transmembrane helices predicted for SEN2158 by TMHMM2.0 at aa 13-33, 48-70, 75-97, 107-126, 139-161, 186-208, 215-237, 252-274, 328-350 and 360-382
550537010774	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537010775	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010776	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010777	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
550537010778	HMMPfam hit to PF04069, Substrate-binding region of ABC-type glycine betaine transport system, score 1.1e-80
550537010779	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
550537010780	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
550537010781	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
550537010782	HMMPfam hit to PF01915, Glycoside hydrolase, family 3, C-terminal, score 6e-101
550537010783	HMMPfam hit to PF00933, Glycoside hydrolase, family 3, N-terminal, score 5.3e-109
550537010784	PS00775 Glycosyl hydrolases family 3 active site.
550537010785	D-lactate dehydrogenase; Provisional; Region: PRK11183
550537010786	FAD binding domain; Region: FAD_binding_4; pfam01565
550537010787	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
550537010788	HMMPfam hit to PF01565, FAD linked oxidase, N-terminal, score 8.3e-11
550537010789	HMMPfam hit to PF09330, D-lactate dehydrogenase, membrane binding, C-terminal, score 7.6e-234
550537010790	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
550537010791	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
550537010792	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
550537010793	HMMPfam hit to PF00768, Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, score 2.2e-123
550537010794	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
550537010795	HMMPfam hit to PF06930, Protein of unknown function DUF1282, score 1.1e-134
550537010796	5 probable transmembrane helices predicted for SEN2163 by TMHMM2.0 at aa 33-55, 65-87, 108-130, 135-157 and 170-192
550537010797	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
550537010798	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
550537010799	5 probable transmembrane helices predicted for SEN2164 by TMHMM2.0 at aa 21-43, 53-72, 100-122, 137-159 and 172-189
550537010800	HMMPfam hit to PF09335, SNARE associated Golgi protein, score 9.2e-06
550537010801	oxidoreductase; Provisional; Region: PRK12743
550537010802	classical (c) SDRs; Region: SDR_c; cd05233
550537010803	NAD(P) binding site [chemical binding]; other site
550537010804	active site
550537010805	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 2e-24
550537010806	PS00061 Short-chain dehydrogenases/reductases family signature.
550537010807	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
550537010808	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.5e-39
550537010809	HMMPfam hit to PF02321, Outer membrane efflux protein, score 5.2e-16
550537010810	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010811	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
550537010812	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
550537010813	FMN binding site [chemical binding]; other site
550537010814	active site
550537010815	catalytic residues [active]
550537010816	substrate binding site [chemical binding]; other site
550537010817	HMMPfam hit to PF01207, Dihydrouridine synthase, DuS, score 1e-132
550537010818	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010819	PS01136 Uncharacterized protein family UPF0034 signature.
550537010820	salicylate hydroxylase; Provisional; Region: PRK08163
550537010821	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
550537010822	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 3.9e-09
550537010823	1 probable transmembrane helix predicted for SEN2168 by TMHMM2.0 at aa 7-24
550537010824	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
550537010825	maleylacetoacetate isomerase; Region: maiA; TIGR01262
550537010826	C-terminal domain interface [polypeptide binding]; other site
550537010827	GSH binding site (G-site) [chemical binding]; other site
550537010828	putative dimer interface [polypeptide binding]; other site
550537010829	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
550537010830	dimer interface [polypeptide binding]; other site
550537010831	N-terminal domain interface [polypeptide binding]; other site
550537010832	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
550537010833	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 5.1e-05
550537010834	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 5.9e-12
550537010835	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
550537010836	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
550537010837	HMMPfam hit to PF01557, Fumarylacetoacetase, C-terminal-like, score 3.3e-57
550537010838	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
550537010839	Cupin domain; Region: Cupin_2; pfam07883
550537010840	Cupin domain; Region: Cupin_2; pfam07883
550537010841	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 0.0012
550537010842	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 1.9e-22
550537010843	benzoate transport; Region: 2A0115; TIGR00895
550537010844	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537010845	putative substrate translocation pore; other site
550537010846	12 probable transmembrane helices predicted for SEN2172 by TMHMM2.0 at aa 23-45, 60-82, 89-108, 113-135, 148-170, 175-197, 253-275, 290-312, 319-338, 342-364, 385-407 and 412-434
550537010847	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.3e-53
550537010848	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
550537010849	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537010850	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537010851	dimerization interface [polypeptide binding]; other site
550537010852	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.8e-17
550537010853	PS00044 Bacterial regulatory proteins, lysR family signature.
550537010854	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.2e-35
550537010855	hypothetical protein; Provisional; Region: PRK01821
550537010856	4 probable transmembrane helices predicted for SEN2174 by TMHMM2.0 at aa 7-29, 34-56, 63-85 and 95-117
550537010857	HMMPfam hit to PF03788, LrgA, score 1e-56
550537010858	hypothetical protein; Provisional; Region: PRK10711
550537010859	5 probable transmembrane helices predicted for SEN2175 by TMHMM2.0 at aa 5-24, 34-56, 91-113, 140-162 and 206-228
550537010860	HMMPfam hit to PF04172, LrgB-like protein, score 3.3e-123
550537010861	cytidine deaminase; Provisional; Region: PRK09027
550537010862	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
550537010863	active site
550537010864	catalytic motif [active]
550537010865	Zn binding site [ion binding]; other site
550537010866	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
550537010867	active site
550537010868	catalytic motif [active]
550537010869	Zn binding site [ion binding]; other site
550537010870	HMMPfam hit to PF00383, CMP/dCMP deaminase, zinc-binding, score 7.4e-23
550537010871	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010872	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
550537010873	HMMPfam hit to PF08211, Cytidine and deoxycytidylate deaminase, zinc-binding region, score 7.5e-75
550537010874	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
550537010875	putative active site [active]
550537010876	1 probable transmembrane helix predicted for SEN2177 by TMHMM2.0 at aa 5-27
550537010877	HMMPfam hit to PF02698, Protein of unknown function DUF218, score 1.4e-39
550537010878	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
550537010879	2 probable transmembrane helices predicted for SEN2178 by TMHMM2.0 at aa 7-26 and 57-79
550537010880	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
550537010881	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
550537010882	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537010883	PS00190 Cytochrome c family heme-binding site signature.
550537010884	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 3.9e-09
550537010885	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 6.1e-09
550537010886	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
550537010887	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
550537010888	homodimer interface [polypeptide binding]; other site
550537010889	active site
550537010890	FMN binding site [chemical binding]; other site
550537010891	substrate binding site [chemical binding]; other site
550537010892	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, core, score 3.2e-18
550537010893	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.00052
550537010894	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.00015
550537010895	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537010896	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
550537010897	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
550537010898	TM-ABC transporter signature motif; other site
550537010899	9 probable transmembrane helices predicted for SEN2181 by TMHMM2.0 at aa 20-42, 49-68, 100-122, 127-149, 179-201, 222-244, 259-281, 286-308 and 312-330
550537010900	HMMPfam hit to PF02653, Bacterial inner-membrane translocator, score 4.6e-65
550537010901	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
550537010902	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
550537010903	Walker A/P-loop; other site
550537010904	ATP binding site [chemical binding]; other site
550537010905	Q-loop/lid; other site
550537010906	ABC transporter signature motif; other site
550537010907	Walker B; other site
550537010908	D-loop; other site
550537010909	H-loop/switch region; other site
550537010910	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
550537010911	HMMPfam hit to PF00005, ABC transporter related, score 1.6e-21
550537010912	PS00211 ABC transporters family signature.
550537010913	HMMPfam hit to PF00005, ABC transporter related, score 4.7e-41
550537010914	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010915	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
550537010916	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
550537010917	ligand binding site [chemical binding]; other site
550537010918	calcium binding site [ion binding]; other site
550537010919	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 0.0013
550537010920	PS00017 ATP/GTP-binding site motif A (P-loop).
550537010921	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
550537010922	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537010923	DNA binding site [nucleotide binding]
550537010924	domain linker motif; other site
550537010925	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
550537010926	dimerization interface (closed form) [polypeptide binding]; other site
550537010927	ligand binding site [chemical binding]; other site
550537010928	PS00134 Serine proteases, trypsin family, histidine active site.
550537010929	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 3.5e-13
550537010930	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 7.9e-13
550537010931	PS00356 Bacterial regulatory proteins, lacI family signature.
550537010932	Predicted membrane protein [Function unknown]; Region: COG2311
550537010933	hypothetical protein; Provisional; Region: PRK10835
550537010934	HMMPfam hit to PF04235, Protein of unknown function DUF418, score 3.3e-57
550537010935	9 probable transmembrane helices predicted for SEN2185 by TMHMM2.0 at aa 12-34, 49-71, 83-102, 107-123, 130-152, 199-221, 233-255, 308-330 and 337-359
550537010936	HMMPfam hit to PF04171, Protein of unknown function DUF405, score 2e-61
550537010937	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
550537010938	GTP cyclohydrolase I; Provisional; Region: PLN03044
550537010939	active site
550537010940	HMMPfam hit to PF01227, GTP cyclohydrolase I, score 8.2e-56
550537010941	PS00860 GTP cyclohydrolase I signature 2.
550537010942	PS00859 GTP cyclohydrolase I signature 1.
550537010943	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
550537010944	S-formylglutathione hydrolase; Region: PLN02442
550537010945	HMMPfam hit to PF00756,  esterase, score 1.6e-110
550537010946	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537010947	non-specific DNA binding site [nucleotide binding]; other site
550537010948	salt bridge; other site
550537010949	sequence-specific DNA binding site [nucleotide binding]; other site
550537010950	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 1.8e-09
550537010951	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
550537010952	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
550537010953	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
550537010954	HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 8.9e-148
550537010955	HMMPfam hit to PF03315, Serine dehydratase beta chain, score 4.7e-22
550537010956	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
550537010957	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
550537010958	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537010959	motif II; other site
550537010960	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.2e-17
550537010961	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
550537010962	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537010963	putative substrate translocation pore; other site
550537010964	11 probable transmembrane helices predicted for SEN2191 by TMHMM2.0 at aa 29-46, 69-91, 103-125, 160-182, 189-208, 240-262, 295-314, 324-343, 348-370, 385-407 and 412-434
550537010965	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.5e-51
550537010966	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010967	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
550537010968	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537010969	N-terminal plug; other site
550537010970	ligand-binding site [chemical binding]; other site
550537010971	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 2.1e-31
550537010972	PS01156 TonB-dependent receptor proteins signature 2.
550537010973	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 2.3e-33
550537010974	PS00430 TonB-dependent receptor proteins signature 1.
550537010975	lysine transporter; Provisional; Region: PRK10836
550537010976	HMMPfam hit to PF00324, Amino acid permease-associated region, score 6.8e-204
550537010977	12 probable transmembrane helices predicted for SEN2193 by TMHMM2.0 at aa 21-43, 53-75, 103-125, 130-152, 159-181, 196-218, 245-267, 287-309, 343-365, 369-391, 412-434 and 444-466
550537010978	PS00218 Amino acid permeases signature.
550537010979	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
550537010980	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537010981	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
550537010982	putative dimerization interface [polypeptide binding]; other site
550537010983	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.2e-56
550537010984	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.1e-18
550537010985	PS00044 Bacterial regulatory proteins, lysR family signature.
550537010986	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
550537010987	8 probable transmembrane helices predicted for SEN2195 by TMHMM2.0 at aa 13-35, 39-61, 100-122, 132-151, 163-185, 262-284, 291-313 and 323-345
550537010988	HMMPfam hit to PF03601, Conserved hypothetical protein CHP00698, score 1e-169
550537010989	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537010990	endonuclease IV; Provisional; Region: PRK01060
550537010991	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
550537010992	AP (apurinic/apyrimidinic) site pocket; other site
550537010993	DNA interaction; other site
550537010994	Metal-binding active site; metal-binding site
550537010995	HMMPfam hit to PF01261, Xylose isomerase-type TIM barrel, score 9.4e-65
550537010996	PS00729 AP endonucleases family 2 signature 1.
550537010997	PS00730 AP endonucleases family 2 signature 2.
550537010998	PS00731 AP endonucleases family 2 signature 3.
550537010999	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
550537011000	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
550537011001	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
550537011002	active site
550537011003	P-loop; other site
550537011004	phosphorylation site [posttranslational modification]
550537011005	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
550537011006	9 probable transmembrane helices predicted for SEN2197 by TMHMM2.0 at aa 236-258, 271-293, 303-325, 345-367, 377-399, 412-434, 464-481, 488-508 and 528-550
550537011007	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.6e-19
550537011008	HMMPfam hit to PF02379, Phosphotransferase system, fructose-specific IIB subunit, score 2e-61
550537011009	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
550537011010	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
550537011011	putative substrate binding site [chemical binding]; other site
550537011012	putative ATP binding site [chemical binding]; other site
550537011013	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 2.8e-71
550537011014	PS00584 pfkB family of carbohydrate kinases signature 2.
550537011015	PS00583 pfkB family of carbohydrate kinases signature 1.
550537011016	PS00464 Ribosomal protein L22 signature.
550537011017	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
550537011018	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537011019	active site
550537011020	phosphorylation site [posttranslational modification]
550537011021	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
550537011022	dimerization domain swap beta strand [polypeptide binding]; other site
550537011023	regulatory protein interface [polypeptide binding]; other site
550537011024	active site
550537011025	regulatory phosphorylation site [posttranslational modification]; other site
550537011026	HMMPfam hit to PF00381, Phosphotransferase system, phosphocarrier HPr protein, score 2.2e-52
550537011027	PS00589 PTS HPR component serine phosphorylation site signature.
550537011028	PS00369 PTS HPR component histidine phosphorylation site signature.
550537011029	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 5.1e-73
550537011030	PS00372 PTS EIIA domains phosphorylation site signature 2.
550537011031	sugar efflux transporter B; Provisional; Region: PRK15011
550537011032	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537011033	putative substrate translocation pore; other site
550537011034	12 probable transmembrane helices predicted for SEN2200 by TMHMM2.0 at aa 20-42, 52-71, 84-101, 105-124, 145-167, 172-194, 221-243, 253-275, 282-304, 308-330, 350-367 and 371-390
550537011035	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.4e-38
550537011036	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011037	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
550537011038	2 probable transmembrane helices predicted for SEN2201 by TMHMM2.0 at aa 21-43 and 184-203
550537011039	1 probable transmembrane helix predicted for SEN2202 by TMHMM2.0 at aa 12-34
550537011040	elongation factor P; Provisional; Region: PRK04542
550537011041	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
550537011042	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
550537011043	RNA binding site [nucleotide binding]; other site
550537011044	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
550537011045	RNA binding site [nucleotide binding]; other site
550537011046	HMMPfam hit to PF08207, Translation elongation factor, KOW-like, score 6.3e-29
550537011047	HMMPfam hit to PF01132, Translation elongation factor P/YeiP, central, score 3.5e-30
550537011048	HMMPfam hit to PF09285, Elongation factor P, C-terminal, score 7.5e-29
550537011049	PS01275 Elongation factor P signature.
550537011050	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
550537011051	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
550537011052	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
550537011053	HMMPfam hit to PF02492, Cobalamin (vitamin B12) biosynthesis CobW-like, score 2.4e-45
550537011054	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011055	HMMPfam hit to PF07683, Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal, score 6.6e-08
550537011056	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
550537011057	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
550537011058	active site
550537011059	5 probable transmembrane helices predicted for SEN2206 by TMHMM2.0 at aa 7-26, 64-83, 95-117, 162-184 and 191-213
550537011060	HMMPfam hit to PF01569, Phosphatidic acid phosphatase type 2-like, score 1.1e-17
550537011061	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
550537011062	NlpC/P60 family; Region: NLPC_P60; pfam00877
550537011063	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011064	HMMPfam hit to PF00877, NLP/P60, score 1.3e-54
550537011065	phage resistance protein; Provisional; Region: PRK10551
550537011066	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
550537011067	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537011068	2 probable transmembrane helices predicted for SEN2208 by TMHMM2.0 at aa 12-34 and 236-258
550537011069	HMMPfam hit to PF00563, EAL, score 3.6e-102
550537011070	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
550537011071	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
550537011072	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 8.2e-56
550537011073	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
550537011074	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537011075	dimer interface [polypeptide binding]; other site
550537011076	conserved gate region; other site
550537011077	putative PBP binding loops; other site
550537011078	ABC-ATPase subunit interface; other site
550537011079	6 probable transmembrane helices predicted for SEN2210 by TMHMM2.0 at aa 9-31, 133-155, 168-190, 224-246, 283-305 and 329-348
550537011080	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.3e-58
550537011081	microcin C ABC transporter permease; Provisional; Region: PRK15021
550537011082	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537011083	dimer interface [polypeptide binding]; other site
550537011084	conserved gate region; other site
550537011085	ABC-ATPase subunit interface; other site
550537011086	6 probable transmembrane helices predicted for SEN2211 by TMHMM2.0 at aa 21-43, 142-164, 177-199, 203-222, 254-276 and 306-328
550537011087	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.1e-46
550537011088	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537011089	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
550537011090	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537011091	Walker A/P-loop; other site
550537011092	ATP binding site [chemical binding]; other site
550537011093	Q-loop/lid; other site
550537011094	ABC transporter signature motif; other site
550537011095	Walker B; other site
550537011096	D-loop; other site
550537011097	H-loop/switch region; other site
550537011098	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
550537011099	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537011100	Walker A/P-loop; other site
550537011101	ATP binding site [chemical binding]; other site
550537011102	Q-loop/lid; other site
550537011103	ABC transporter signature motif; other site
550537011104	Walker B; other site
550537011105	D-loop; other site
550537011106	H-loop/switch region; other site
550537011107	HMMPfam hit to PF00005, ABC transporter related, score 9.2e-62
550537011108	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011109	PS00211 ABC transporters family signature.
550537011110	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 0.00018
550537011111	HMMPfam hit to PF00005, ABC transporter related, score 8.5e-58
550537011112	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011113	PS00211 ABC transporters family signature.
550537011114	hypothetical protein; Provisional; Region: PRK11835
550537011115	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537011116	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
550537011117	putative substrate translocation pore; other site
550537011118	12 probable transmembrane helices predicted for SEN2214 by TMHMM2.0 at aa 7-26, 41-63, 76-98, 102-124, 137-159, 163-185, 219-241, 251-273, 286-308, 313-332, 345-367 and 372-391
550537011119	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.2e-57
550537011120	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011121	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011122	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
550537011123	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537011124	RNA binding surface [nucleotide binding]; other site
550537011125	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
550537011126	active site
550537011127	uracil binding [chemical binding]; other site
550537011128	HMMPfam hit to PF00849, Pseudouridine synthase, score 3.5e-28
550537011129	PS01149 Rsu family of pseudouridine synthase signature.
550537011130	HMMPfam hit to PF01479, RNA-binding S4, score 3.8e-09
550537011131	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
550537011132	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537011133	ATP binding site [chemical binding]; other site
550537011134	putative Mg++ binding site [ion binding]; other site
550537011135	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537011136	nucleotide binding region [chemical binding]; other site
550537011137	ATP-binding site [chemical binding]; other site
550537011138	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
550537011139	HMMPfam hit to PF04851, Restriction endonuclease, type I, R subunit/Type III, Res subunit, score 3.8e-41
550537011140	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 3.2e-14
550537011141	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011142	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
550537011143	5S rRNA interface [nucleotide binding]; other site
550537011144	CTC domain interface [polypeptide binding]; other site
550537011145	L16 interface [polypeptide binding]; other site
550537011146	HMMPfam hit to PF01386, Ribosomal protein L25, score 2.5e-49
550537011147	2 probable transmembrane helices predicted for SEN2218 by TMHMM2.0 at aa 20-42 and 52-74
550537011148	Nucleoid-associated protein [General function prediction only]; Region: COG3081
550537011149	nucleoid-associated protein NdpA; Validated; Region: PRK00378
550537011150	HMMPfam hit to PF04245, 37kDa nucleoid-associated bacterial protein, score 9.4e-173
550537011151	hypothetical protein; Provisional; Region: PRK13689
550537011152	HMMPfam hit to PF07208, Protein of unknown function DUF1414, score 3.1e-50
550537011153	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
550537011154	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
550537011155	Sulfatase; Region: Sulfatase; cl17466
550537011156	PS00430 TonB-dependent receptor proteins signature 1.
550537011157	5 probable transmembrane helices predicted for SEN2221 by TMHMM2.0 at aa 21-43, 58-80, 85-103, 135-157 and 169-191
550537011158	HMMPfam hit to PF00884, Sulphatase, score 9.2e-64
550537011160	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
550537011161	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
550537011162	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
550537011163	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
550537011164	Leucine-rich repeats; other site
550537011165	Substrate binding site [chemical binding]; other site
550537011166	HMMPfam hit to PF00560, Leucine-rich repeat, score 3.6
550537011167	HMMPfam hit to PF00560, Leucine-rich repeat, score 5.7
550537011168	HMMPfam hit to PF00560, Leucine-rich repeat, score 1.7
550537011169	HMMPfam hit to PF00560, Leucine-rich repeat, score 1.7
550537011170	HMMPfam hit to PF00560, Leucine-rich repeat, score 3
550537011172	HMMPfam hit to PF02413, Phage tail assembly chaperone gp38, score 1.6e-09
550537011173	Note the premature stop codon after codon 154
550537011174	HMMPfam hit to PF03406, Phage tail fiber repeat 2, score 1.6e-15
550537011175	DinI-like family; Region: DinI; cl11630
550537011176	HMMPfam hit to PF06183, DinI-like, score 5.9e-05
550537011177	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
550537011178	2 probable transmembrane helices predicted for SEN2228 by TMHMM2.0 at aa 7-26 and 108-126
550537011179	transcriptional regulator NarP; Provisional; Region: PRK10403
550537011180	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537011181	active site
550537011182	phosphorylation site [posttranslational modification]
550537011183	intermolecular recognition site; other site
550537011184	dimerization interface [polypeptide binding]; other site
550537011185	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537011186	DNA binding residues [nucleotide binding]
550537011187	dimerization interface [polypeptide binding]; other site
550537011188	HMMPfam hit to PF00072, Response regulator receiver, score 9.7e-42
550537011189	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1.6e-29
550537011190	PS00622 Bacterial regulatory proteins, luxR family signature.
550537011191	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
550537011192	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
550537011193	2 probable transmembrane helices predicted for SEN2230 by TMHMM2.0 at aa 103-125 and 150-172
550537011194	HMMPfam hit to PF03918, Cytochrome C biogenesis protein, score 2.2e-71
550537011195	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
550537011196	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
550537011197	catalytic residues [active]
550537011198	central insert; other site
550537011199	HMMPfam hit to PF08534, Redoxin, score 2.5e-27
550537011200	PS00194 Thioredoxin family active site.
550537011201	1 probable transmembrane helix predicted for SEN2231 by TMHMM2.0 at aa 5-24
550537011202	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
550537011203	15 probable transmembrane helices predicted for SEN2232 by TMHMM2.0 at aa 5-27, 40-62, 95-114, 121-143, 176-198, 211-233, 248-265, 277-299, 314-332, 353-375, 390-412, 425-444, 449-468, 481-503 and 610-629
550537011204	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011205	HMMPfam hit to PF01578, Cytochrome c assembly protein, score 1.3e-82
550537011206	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
550537011207	HMMPfam hit to PF03100, CcmE/CycJ protein, score 1.2e-90
550537011208	1 probable transmembrane helix predicted for SEN2233 by TMHMM2.0 at aa 7-29
550537011209	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
550537011210	HMMPfam hit to PF04995, Heme exporter protein D (CcmD), score 2.7e-16
550537011211	1 probable transmembrane helix predicted for SEN2234 by TMHMM2.0 at aa 15-37
550537011212	heme exporter protein CcmC; Region: ccmC; TIGR01191
550537011213	6 probable transmembrane helices predicted for SEN2235 by TMHMM2.0 at aa 21-43, 63-85, 92-114, 129-148, 155-177 and 204-226
550537011214	HMMPfam hit to PF01578, Cytochrome c assembly protein, score 5e-57
550537011215	heme exporter protein CcmB; Region: ccmB; TIGR01190
550537011216	HMMPfam hit to PF03379, Cytochrome c-type biogenesis protein CcmB, score 6.4e-113
550537011217	6 probable transmembrane helices predicted for SEN2236 by TMHMM2.0 at aa 21-38, 42-64, 95-117, 127-149, 156-178 and 193-215
550537011218	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
550537011219	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537011220	Walker A/P-loop; other site
550537011221	ATP binding site [chemical binding]; other site
550537011222	Q-loop/lid; other site
550537011223	ABC transporter signature motif; other site
550537011224	Walker B; other site
550537011225	D-loop; other site
550537011226	H-loop/switch region; other site
550537011227	HMMPfam hit to PF00005, ABC transporter related, score 1.4e-48
550537011228	PS00211 ABC transporters family signature.
550537011229	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011230	cytochrome c-type protein NapC; Provisional; Region: PRK10617
550537011231	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
550537011232	HMMPfam hit to PF03264, NapC/NirT cytochrome c, N-terminal, score 1.2e-125
550537011233	PS00190 Cytochrome c family heme-binding site signature.
550537011234	PS00190 Cytochrome c family heme-binding site signature.
550537011235	PS00190 Cytochrome c family heme-binding site signature.
550537011236	1 probable transmembrane helix predicted for SEN2238 by TMHMM2.0 at aa 21-43
550537011237	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
550537011238	HMMPfam hit to PF03892, Nitrate reductase cytochrome c-type subunit (NapB), score 5.7e-51
550537011239	PS00190 Cytochrome c family heme-binding site signature.
550537011240	PS00190 Cytochrome c family heme-binding site signature.
550537011241	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
550537011242	4Fe-4S binding domain; Region: Fer4_5; pfam12801
550537011243	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
550537011244	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.00059
550537011245	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011246	4 probable transmembrane helices predicted for SEN2240 by TMHMM2.0 at aa 33-55, 75-97, 138-160 and 170-192
550537011247	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
550537011248	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0022
550537011249	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 8.3e-06
550537011250	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011251	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
550537011252	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
550537011253	[4Fe-4S] binding site [ion binding]; other site
550537011254	molybdopterin cofactor binding site; other site
550537011255	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
550537011256	molybdopterin cofactor binding site; other site
550537011257	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 4.6e-34
550537011258	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 2.2e-139
550537011259	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 2.4e-23
550537011260	PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
550537011261	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
550537011262	HMMPfam hit to PF03927, NapD, score 1.7e-35
550537011263	ferredoxin-type protein; Provisional; Region: PRK10194
550537011264	4Fe-4S binding domain; Region: Fer4; cl02805
550537011265	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 3.7e-07
550537011266	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011267	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0022
550537011268	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011269	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
550537011270	secondary substrate binding site; other site
550537011271	primary substrate binding site; other site
550537011272	inhibition loop; other site
550537011273	dimerization interface [polypeptide binding]; other site
550537011274	HMMPfam hit to PF03974, Proteinase inhibitor I11, ecotin, score 3.7e-118
550537011275	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011276	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
550537011277	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
550537011278	Walker A/P-loop; other site
550537011279	ATP binding site [chemical binding]; other site
550537011280	Q-loop/lid; other site
550537011281	ABC transporter signature motif; other site
550537011282	Walker B; other site
550537011283	D-loop; other site
550537011284	H-loop/switch region; other site
550537011285	HMMPfam hit to PF00005, ABC transporter related, score 6.9e-44
550537011286	PS00211 ABC transporters family signature.
550537011287	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011288	6 probable transmembrane helices predicted for SEN2246 by TMHMM2.0 at aa 15-37, 50-72, 120-142, 149-171, 238-260 and 272-294
550537011289	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
550537011290	HMMPfam hit to PF03171, 2OG-Fe(II) oxygenase, score 3.6e-08
550537011291	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
550537011292	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
550537011293	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537011294	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
550537011295	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
550537011296	DNA binding site [nucleotide binding]
550537011297	active site
550537011298	HMMPfam hit to PF01035, Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding, score 5.7e-57
550537011299	PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
550537011300	HMMPfam hit to PF02870, Methylguanine DNA methyltransferase, ribonuclease-like, score 4.1e-23
550537011301	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 6.7e-05
550537011302	PS00041 Bacterial regulatory proteins, araC family signature.
550537011303	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 5.5e-10
550537011304	PS00041 Bacterial regulatory proteins, araC family signature.
550537011305	HMMPfam hit to PF02805, Ada, metal-binding, score 5.7e-44
550537011306	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
550537011307	ApbE family; Region: ApbE; pfam02424
550537011308	HMMPfam hit to PF02424, ApbE-like lipoprotein, score 7.4e-140
550537011309	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011310	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011311	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
550537011312	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
550537011313	trimer interface [polypeptide binding]; other site
550537011314	eyelet of channel; other site
550537011315	HMMPfam hit to PF00267, Porin, Gram-negative type, score 2.1e-214
550537011316	PS00576 General diffusion Gram-negative porins signature.
550537011317	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537011318	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
550537011319	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537011320	ATP binding site [chemical binding]; other site
550537011321	G-X-G motif; other site
550537011322	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
550537011323	putative binding surface; other site
550537011324	active site
550537011325	2 probable transmembrane helices predicted for SEN2251 by TMHMM2.0 at aa 20-42 and 308-330
550537011326	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.8e-14
550537011327	HMMPfam hit to PF01627, Hpt, score 2.5e-15
550537011328	transcriptional regulator RcsB; Provisional; Region: PRK10840
550537011329	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537011330	active site
550537011331	phosphorylation site [posttranslational modification]
550537011332	intermolecular recognition site; other site
550537011333	dimerization interface [polypeptide binding]; other site
550537011334	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537011335	DNA binding residues [nucleotide binding]
550537011336	dimerization interface [polypeptide binding]; other site
550537011337	HMMPfam hit to PF00072, Response regulator receiver, score 1.5e-33
550537011338	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 6e-22
550537011339	PS00622 Bacterial regulatory proteins, luxR family signature.
550537011340	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
550537011341	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537011342	dimer interface [polypeptide binding]; other site
550537011343	phosphorylation site [posttranslational modification]
550537011344	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537011345	ATP binding site [chemical binding]; other site
550537011346	Mg2+ binding site [ion binding]; other site
550537011347	G-X-G motif; other site
550537011348	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
550537011349	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537011350	active site
550537011351	phosphorylation site [posttranslational modification]
550537011352	intermolecular recognition site; other site
550537011353	dimerization interface [polypeptide binding]; other site
550537011354	HMMPfam hit to PF00072, Response regulator receiver, score 1.4e-41
550537011355	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 7.7e-44
550537011356	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.2e-21
550537011357	2 probable transmembrane helices predicted for SEN2253 by TMHMM2.0 at aa 20-42 and 314-333
550537011358	DNA gyrase subunit A; Validated; Region: PRK05560
550537011359	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
550537011360	CAP-like domain; other site
550537011361	active site
550537011362	primary dimer interface [polypeptide binding]; other site
550537011363	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
550537011364	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
550537011365	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
550537011366	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
550537011367	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
550537011368	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
550537011369	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 9e-14
550537011370	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 4.5e-15
550537011371	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 1.3e-16
550537011372	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 4.1e-10
550537011373	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 3.7e-15
550537011374	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 4.3e-13
550537011375	HMMPfam hit to PF00521, DNA topoisomerase, type IIA, subunit A or C-terminal, score 0
550537011376	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
550537011377	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
550537011378	active site pocket [active]
550537011379	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 4.5e-16
550537011380	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 1.1e-27
550537011381	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
550537011382	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537011383	putative substrate translocation pore; other site
550537011384	12 probable transmembrane helices predicted for SEN2256 by TMHMM2.0 at aa 20-42, 55-77, 84-103, 109-131, 144-166, 176-198, 247-269, 284-306, 315-334, 339-361, 368-390 and 400-422
550537011385	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 6.4e-51
550537011386	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011387	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537011388	Transcriptional regulators [Transcription]; Region: GntR; COG1802
550537011389	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537011390	DNA-binding site [nucleotide binding]; DNA binding site
550537011391	FCD domain; Region: FCD; pfam07729
550537011392	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 9.5e-15
550537011393	HMMPfam hit to PF07729, GntR, C-terminal, score 0.00016
550537011394	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
550537011395	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537011396	S-adenosylmethionine binding site [chemical binding]; other site
550537011397	HMMPfam hit to PF08241, Methyltransferase type 11, score 2.2e-26
550537011398	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
550537011399	ATP cone domain; Region: ATP-cone; pfam03477
550537011400	Class I ribonucleotide reductase; Region: RNR_I; cd01679
550537011401	active site
550537011402	dimer interface [polypeptide binding]; other site
550537011403	catalytic residues [active]
550537011404	effector binding site; other site
550537011405	R2 peptide binding site; other site
550537011406	HMMPfam hit to PF03477, ATP-cone, score 5.1e-23
550537011407	HMMPfam hit to PF00317, Ribonucleotide reductase large subunit, N-terminal, score 6.1e-24
550537011408	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011409	HMMPfam hit to PF02867, Ribonucleotide reductase large subunit, C-terminal, score 5.5e-273
550537011410	PS00089 Ribonucleotide reductase large subunit signature.
550537011411	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
550537011412	dimer interface [polypeptide binding]; other site
550537011413	putative radical transfer pathway; other site
550537011414	diiron center [ion binding]; other site
550537011415	tyrosyl radical; other site
550537011416	PS00368 Ribonucleotide reductase small subunit signature.
550537011417	HMMPfam hit to PF00268, Ribonucleotide reductase, score 6.3e-11
550537011418	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
550537011419	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
550537011420	catalytic loop [active]
550537011421	iron binding site [ion binding]; other site
550537011422	HMMPfam hit to PF00111, Ferredoxin, score 5.7e-15
550537011423	PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature.
550537011424	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537011425	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537011426	putative substrate translocation pore; other site
550537011427	12 probable transmembrane helices predicted for SEN2262 by TMHMM2.0 at aa 13-35, 45-64, 76-95, 100-122, 135-154, 164-186, 208-230, 240-262, 269-291, 295-317, 330-352 and 357-379
550537011428	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5.7e-53
550537011429	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
550537011430	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537011431	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
550537011432	dimerization interface [polypeptide binding]; other site
550537011433	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.3e-15
550537011434	PS00044 Bacterial regulatory proteins, lysR family signature.
550537011435	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.9e-34
550537011436	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
550537011437	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
550537011438	active site
550537011439	catalytic site [active]
550537011440	metal binding site [ion binding]; metal-binding site
550537011441	HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 8e-110
550537011442	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011443	1 probable transmembrane helix predicted for SEN2264 by TMHMM2.0 at aa 7-26
550537011444	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
550537011445	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537011446	putative substrate translocation pore; other site
550537011447	12 probable transmembrane helices predicted for SEN2265 by TMHMM2.0 at aa 28-45, 65-87, 94-116, 120-142, 161-183, 188-207, 254-273, 293-312, 319-341, 351-373, 386-408 and 418-437
550537011448	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.6e-48
550537011449	PS00942 glpT family of transporters signature.
550537011450	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
550537011451	hydroxyglutarate oxidase; Provisional; Region: PRK11728
550537011452	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
550537011453	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 3.8e-71
550537011454	PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1.
550537011455	PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2.
550537011456	HMMPfam hit to PF04324, BFD-like [2Fe-2S]-binding region, score 3.2e-18
550537011457	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
550537011458	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
550537011459	HMMPfam hit to PF00890, Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal, score 2.3e-88
550537011460	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
550537011461	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
550537011462	Cysteine-rich domain; Region: CCG; pfam02754
550537011463	Cysteine-rich domain; Region: CCG; pfam02754
550537011464	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011465	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0022
550537011466	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011467	HMMPfam hit to PF02754, Cysteine-rich region, CCG, score 9.9e-09
550537011468	HMMPfam hit to PF02754, Cysteine-rich region, CCG, score 6.8e-17
550537011469	deubiquitinase SseL; Provisional; Region: PRK14848
550537011470	hypothetical protein; Provisional; Region: PRK03673
550537011471	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
550537011472	HMMPfam hit to PF03328, HpcH/HpaI aldolase, score 6.4e-109
550537011474	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 8.2e-49
550537011475	L-rhamnonate dehydratase; Provisional; Region: PRK15440
550537011476	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
550537011477	putative active site pocket [active]
550537011478	putative metal binding site [ion binding]; other site
550537011479	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 1.7e-27
550537011480	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 0.00026
550537011481	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
550537011482	Transcriptional regulator [Transcription]; Region: IclR; COG1414
550537011483	Bacterial transcriptional regulator; Region: IclR; pfam01614
550537011484	HMMPfam hit to PF01614, Transcriptional regulator IclR, C-terminal, score 1.9e-53
550537011485	PS01051 Bacterial regulatory proteins, iclR family signature.
550537011486	HMMPfam hit to PF09339, Transcriptional regulator IclR, N-terminal, score 3e-13
550537011487	hypothetical protein; Provisional; Region: PRK03673
550537011488	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
550537011489	putative MPT binding site; other site
550537011490	Competence-damaged protein; Region: CinA; cl00666
550537011491	HMMPfam hit to PF00994, Molybdopterin binding, score 1.7e-48
550537011492	YfaZ precursor; Region: YfaZ; pfam07437
550537011493	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
550537011494	HMMPfam hit to PF07437, YfaZ, score 1.7e-114
550537011495	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
550537011496	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 4.3e-28
550537011497	PS00893 mutT domain signature.
550537011498	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
550537011499	catalytic core [active]
550537011500	HMMPfam hit to PF00300, Phosphoglycerate mutase, score 6.6e-10
550537011501	1 probable transmembrane helix predicted for SEN2278 by TMHMM2.0 at aa 13-35
550537011502	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
550537011503	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
550537011504	inhibitor-cofactor binding pocket; inhibition site
550537011505	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537011506	catalytic residue [active]
550537011507	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 6.1e-180
550537011508	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
550537011509	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
550537011510	Ligand binding site; other site
550537011511	Putative Catalytic site; other site
550537011512	DXD motif; other site
550537011513	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 9.1e-36
550537011514	2 probable transmembrane helices predicted for SEN2280 by TMHMM2.0 at aa 235-257 and 272-294
550537011515	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
550537011516	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
550537011517	active site
550537011518	substrate binding site [chemical binding]; other site
550537011519	cosubstrate binding site; other site
550537011520	catalytic site [active]
550537011521	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
550537011522	active site
550537011523	hexamer interface [polypeptide binding]; other site
550537011524	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
550537011525	NAD binding site [chemical binding]; other site
550537011526	substrate binding site [chemical binding]; other site
550537011527	active site
550537011528	HMMPfam hit to PF00551, Formyl transferase, N-terminal, score 3.2e-11
550537011529	HMMPfam hit to PF02911, Formyl transferase, C-terminal, score 3.2e-33
550537011530	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 2.7e-49
550537011531	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
550537011532	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
550537011533	putative active site [active]
550537011534	putative catalytic site [active]
550537011535	putative Zn binding site [ion binding]; other site
550537011536	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 0.00027
550537011537	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
550537011538	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
550537011539	HMMPfam hit to PF02366, Glycosyl transferase, family 39, score 5.5e-72
550537011540	12 probable transmembrane helices predicted for SEN2283 by TMHMM2.0 at aa 7-29, 82-104, 113-135, 139-156, 163-185, 205-227, 258-280, 290-307, 314-331, 346-368, 381-400 and 405-424
550537011541	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011542	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
550537011543	3 probable transmembrane helices predicted for SEN2284 by TMHMM2.0 at aa 36-58, 63-85 and 92-110
550537011544	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2.5e-08
550537011545	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
550537011546	4 probable transmembrane helices predicted for SEN2285 by TMHMM2.0 at aa 5-27, 42-64, 71-90 and 100-122
550537011547	signal transduction protein PmrD; Provisional; Region: PRK15450
550537011548	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
550537011549	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
550537011550	acyl-activating enzyme (AAE) consensus motif; other site
550537011551	putative AMP binding site [chemical binding]; other site
550537011552	putative active site [active]
550537011553	putative CoA binding site [chemical binding]; other site
550537011554	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 6.8e-62
550537011555	PS00455  AMP-binding domain signature.
550537011556	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
550537011557	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
550537011558	active site
550537011559	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 1.1e-11
550537011560	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
550537011561	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
550537011562	substrate binding site [chemical binding]; other site
550537011563	oxyanion hole (OAH) forming residues; other site
550537011564	trimer interface [polypeptide binding]; other site
550537011565	HMMPfam hit to PF00378, Crotonase, core, score 1.2e-73
550537011566	PS00166 Enoyl-CoA hydratase/isomerase signature.
550537011567	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
550537011568	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 5e-09
550537011569	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
550537011570	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
550537011571	dimer interface [polypeptide binding]; other site
550537011572	tetramer interface [polypeptide binding]; other site
550537011573	PYR/PP interface [polypeptide binding]; other site
550537011574	TPP binding site [chemical binding]; other site
550537011575	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
550537011576	TPP-binding site; other site
550537011577	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
550537011578	isochorismate synthases; Region: isochor_syn; TIGR00543
550537011579	HMMPfam hit to PF00425, Chorismate binding, C-terminal, score 1.1e-18
550537011580	hypothetical protein; Provisional; Region: PRK10404
550537011581	HMMPfam hit to PF05957, Protein of unknown function DUF883, ElaB, score 3.4e-49
550537011582	1 probable transmembrane helix predicted for SEN2293 by TMHMM2.0 at aa 82-101
550537011583	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537011584	Coenzyme A binding pocket [chemical binding]; other site
550537011585	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 1.4e-10
550537011586	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
550537011587	HMMPfam hit to PF00753, Beta-lactamase-like, score 4e-10
550537011588	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011589	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
550537011590	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
550537011591	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537011592	active site
550537011593	phosphorylation site [posttranslational modification]
550537011594	intermolecular recognition site; other site
550537011595	dimerization interface [polypeptide binding]; other site
550537011596	HMMPfam hit to PF01584, CheW-like protein, score 6.4e-28
550537011597	HMMPfam hit to PF00072, Response regulator receiver, score 1.8e-07
550537011598	von Willebrand factor; Region: vWF_A; pfam12450
550537011599	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
550537011600	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
550537011601	metal ion-dependent adhesion site (MIDAS); other site
550537011602	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
550537011603	HMMPfam hit to PF00092, von Willebrand factor, type A, score 4e-24
550537011604	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011605	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
550537011606	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
550537011607	14 probable transmembrane helices predicted for SEN2298 by TMHMM2.0 at aa 6-28, 35-57, 72-94, 106-120, 125-147, 159-181, 201-223, 236-258, 268-290, 297-319, 329-351, 371-393, 408-430 and 450-472
550537011608	HMMPfam hit to PF00361, NADH/Ubiquinone/plastoquinone (complex I), score 1.2e-96
550537011609	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
550537011610	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
550537011611	14 probable transmembrane helices predicted for SEN2299 by TMHMM2.0 at aa 4-18, 30-49, 81-103, 115-134, 139-161, 174-196, 222-244, 251-273, 288-307, 314-336, 341-363, 384-406, 416-438 and 459-481
550537011612	HMMPfam hit to PF00361, NADH/Ubiquinone/plastoquinone (complex I), score 2.4e-75
550537011613	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
550537011614	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
550537011615	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
550537011616	16 probable transmembrane helices predicted for SEN2300 by TMHMM2.0 at aa 4-21, 28-50, 84-106, 113-132, 136-158, 171-193, 213-235, 248-267, 277-299, 306-328, 332-354, 375-397, 412-434, 455-477, 492-514 and 590-612
550537011617	HMMPfam hit to PF00361, NADH/Ubiquinone/plastoquinone (complex I), score 9e-121
550537011618	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011619	HMMPfam hit to PF00662, NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal, score 1.5e-29
550537011620	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
550537011621	HMMPfam hit to PF00420, NADH-ubiquinone oxidoreductase, chain 4L, score 7.1e-32
550537011622	3 probable transmembrane helices predicted for SEN2301 by TMHMM2.0 at aa 4-23, 28-50 and 60-82
550537011623	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
550537011624	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
550537011625	HMMPfam hit to PF00499, NADH-ubiquinone/plastoquinone oxidoreductase, chain 6, score 9e-32
550537011626	5 probable transmembrane helices predicted for SEN2302 by TMHMM2.0 at aa 4-22, 29-51, 56-78, 91-113 and 133-155
550537011627	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
550537011628	4Fe-4S binding domain; Region: Fer4; pfam00037
550537011629	4Fe-4S binding domain; Region: Fer4; pfam00037
550537011630	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.8e-08
550537011631	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011632	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.00012
550537011633	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537011634	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
550537011635	9 probable transmembrane helices predicted for SEN2304 by TMHMM2.0 at aa 13-35, 50-69, 81-103, 113-135, 155-174, 184-206, 235-257, 267-289 and 302-324
550537011636	HMMPfam hit to PF00146, Respiratory-chain NADH dehydrogenase, subunit 1, score 1.1e-184
550537011637	PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2.
550537011638	PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1.
550537011639	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
550537011640	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
550537011641	catalytic loop [active]
550537011642	iron binding site [ion binding]; other site
550537011643	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
550537011644	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
550537011645	[4Fe-4S] binding site [ion binding]; other site
550537011646	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
550537011647	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 9.8e-06
550537011648	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 0.0002
550537011649	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 4.4e-15
550537011650	PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3.
550537011651	PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2.
550537011652	HMMPfam hit to PF00111, Ferredoxin, score 4.8e-14
550537011653	PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1.
550537011654	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011655	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
550537011656	SLBB domain; Region: SLBB; pfam10531
550537011657	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
550537011658	PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2.
550537011659	HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit, score 5.1e-181
550537011660	PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1.
550537011661	NADH dehydrogenase subunit E; Validated; Region: PRK07539
550537011662	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
550537011663	putative dimer interface [polypeptide binding]; other site
550537011664	[2Fe-2S] cluster binding site [ion binding]; other site
550537011665	HMMPfam hit to PF01257, NADH dehydrogenase (ubiquinone), 24 kDa subunit, score 1e-103
550537011666	PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature.
550537011667	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
550537011668	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
550537011669	NADH dehydrogenase subunit D; Validated; Region: PRK06075
550537011670	HMMPfam hit to PF00346, NADH-ubiquinone oxidoreductase, chain 49kDa, score 1.5e-216
550537011671	PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature.
550537011672	HMMPfam hit to PF00329, NADH dehydrogenase (ubiquinone), 30 kDa subunit, score 4.2e-40
550537011673	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
550537011674	HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 kDa subunit, score 1.5e-56
550537011675	PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature.
550537011676	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011677	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
550537011678	HMMPfam hit to PF00507, NADH-ubiquinone/plastoquinone oxidoreductase, chain 3, score 5.1e-37
550537011679	3 probable transmembrane helices predicted for SEN2310 by TMHMM2.0 at aa 15-37, 68-90 and 100-122
550537011680	PS00012 Phosphopantetheine attachment site.
550537011681	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
550537011682	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537011683	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
550537011684	putative dimerization interface [polypeptide binding]; other site
550537011685	HMMPfam hit to PF03466, LysR, substrate-binding, score 7.9e-30
550537011686	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
550537011687	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2.8e-16
550537011688	PS00044 Bacterial regulatory proteins, lysR family signature.
550537011689	aminotransferase AlaT; Validated; Region: PRK09265
550537011690	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537011691	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537011692	homodimer interface [polypeptide binding]; other site
550537011693	catalytic residue [active]
550537011694	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 3e-38
550537011695	5'-nucleotidase; Provisional; Region: PRK03826
550537011696	HMMPfam hit to PF01966, Metal-dependent phosphohydrolase, HD region, subdomain, score 1.2e-15
550537011697	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
550537011698	transmembrane helices; other site
550537011699	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
550537011700	TrkA-C domain; Region: TrkA_C; pfam02080
550537011701	TrkA-C domain; Region: TrkA_C; pfam02080
550537011702	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
550537011703	11 probable transmembrane helices predicted for SEN2315 by TMHMM2.0 at aa 5-22, 29-51, 61-83, 96-118, 138-160, 173-195, 427-449, 462-480, 500-522, 542-564 and 584-606
550537011704	PS01271 Sodium:sulfate symporter family signature.
550537011705	HMMPfam hit to PF03600, Divalent ion symporter, score 3.2e-51
550537011706	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011707	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011708	HMMPfam hit to PF02080, TrkA-C, score 1.8e-08
550537011709	HMMPfam hit to PF02080, TrkA-C, score 7.8e-12
550537011710	putative phosphatase; Provisional; Region: PRK11587
550537011711	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537011712	motif II; other site
550537011713	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 4.1e-40
550537011714	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011715	hypothetical protein; Validated; Region: PRK05445
550537011716	HMMPfam hit to PF03887, YfbU, score 1.1e-118
550537011717	hypothetical protein; Provisional; Region: PRK01816
550537011718	HMMPfam hit to PF04217, Protein of unknown function DUF412, score 1.6e-108
550537011719	2 probable transmembrane helices predicted for SEN2318 by TMHMM2.0 at aa 46-65 and 69-91
550537011720	propionate/acetate kinase; Provisional; Region: PRK12379
550537011721	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
550537011722	HMMPfam hit to PF00871, Acetate and butyrate kinase, score 2.9e-258
550537011723	PS01075 Acetate and butyrate kinases family signature 1.
550537011724	PS01076 Acetate and butyrate kinases family signature 2.
550537011725	phosphate acetyltransferase; Reviewed; Region: PRK05632
550537011726	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
550537011727	DRTGG domain; Region: DRTGG; pfam07085
550537011728	phosphate acetyltransferase; Region: pta; TIGR00651
550537011729	HMMPfam hit to PF07085, DRTGG, score 9.4e-58
550537011730	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 3.7e-191
550537011731	hypothetical protein; Provisional; Region: PRK11588
550537011732	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
550537011733	HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 2.7e-233
550537011734	11 probable transmembrane helices predicted for SEN2321 by TMHMM2.0 at aa 19-41, 106-127, 148-165, 175-197, 204-226, 230-252, 287-309, 314-336, 349-371, 398-415 and 481-503
550537011735	PS00012 Phosphopantetheine attachment site.
550537011736	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
550537011737	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
550537011738	PYR/PP interface [polypeptide binding]; other site
550537011739	dimer interface [polypeptide binding]; other site
550537011740	TPP binding site [chemical binding]; other site
550537011741	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
550537011742	HMMPfam hit to PF02780, Transketolase, C-terminal, score 1.2e-39
550537011743	HMMPfam hit to PF02779, Transketolase, central region, score 2.6e-15
550537011744	transketolase; Reviewed; Region: PRK05899
550537011745	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
550537011746	TPP-binding site [chemical binding]; other site
550537011747	dimer interface [polypeptide binding]; other site
550537011748	HMMPfam hit to PF00456, Transketolase, N-terminal, score 2.5e-40
550537011749	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
550537011750	11 probable transmembrane helices predicted for SEN2324 by TMHMM2.0 at aa 10-32, 39-61, 95-114, 121-143, 147-169, 226-243, 258-280, 310-332, 342-364, 377-399 and 423-445
550537011751	HMMPfam hit to PF04215,  sugar-specific permease, SgaT/UlaA, score 8.8e-128
550537011752	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
550537011753	active site
550537011754	P-loop; other site
550537011755	phosphorylation site [posttranslational modification]
550537011756	HMMPfam hit to PF02302, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, score 1.9e-20
550537011757	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537011758	active site
550537011759	phosphorylation site [posttranslational modification]
550537011760	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 6.9e-36
550537011761	Transcriptional regulators [Transcription]; Region: PurR; COG1609
550537011762	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537011763	DNA binding site [nucleotide binding]
550537011764	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
550537011765	putative dimerization interface [polypeptide binding]; other site
550537011766	putative ligand binding site [chemical binding]; other site
550537011767	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 5.7e-10
550537011768	PS00356 Bacterial regulatory proteins, lacI family signature.
550537011769	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 4.6e-08
550537011770	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
550537011771	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
550537011772	nudix motif; other site
550537011773	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 2.1e-27
550537011774	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
550537011775	active site
550537011776	metal binding site [ion binding]; metal-binding site
550537011777	homotetramer interface [polypeptide binding]; other site
550537011778	PS01269 Uncharacterized protein family UPF0025 signature.
550537011779	HMMPfam hit to PF00149, Metallophosphoesterase, score 5.1e-16
550537011780	glutathione S-transferase; Provisional; Region: PRK15113
550537011781	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
550537011782	C-terminal domain interface [polypeptide binding]; other site
550537011783	GSH binding site (G-site) [chemical binding]; other site
550537011784	dimer interface [polypeptide binding]; other site
550537011785	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
550537011786	N-terminal domain interface [polypeptide binding]; other site
550537011787	putative dimer interface [polypeptide binding]; other site
550537011788	putative substrate binding pocket (H-site) [chemical binding]; other site
550537011789	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 1.5e-11
550537011790	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
550537011791	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
550537011792	C-terminal domain interface [polypeptide binding]; other site
550537011793	GSH binding site (G-site) [chemical binding]; other site
550537011794	dimer interface [polypeptide binding]; other site
550537011795	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
550537011796	N-terminal domain interface [polypeptide binding]; other site
550537011797	putative dimer interface [polypeptide binding]; other site
550537011798	active site
550537011799	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 1.3e-07
550537011800	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 1.7e-10
550537011801	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
550537011802	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
550537011803	putative NAD(P) binding site [chemical binding]; other site
550537011804	putative active site [active]
550537011805	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 3.5e-22
550537011806	HMMPfam hit to PF08338, Region of unknown function DUF1731, score 3.1e-23
550537011807	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
550537011808	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
550537011809	Walker A/P-loop; other site
550537011810	ATP binding site [chemical binding]; other site
550537011811	Q-loop/lid; other site
550537011812	ABC transporter signature motif; other site
550537011813	Walker B; other site
550537011814	D-loop; other site
550537011815	H-loop/switch region; other site
550537011816	HMMPfam hit to PF00005, ABC transporter related, score 1.2e-63
550537011817	PS00211 ABC transporters family signature.
550537011818	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011819	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537011820	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537011821	dimer interface [polypeptide binding]; other site
550537011822	conserved gate region; other site
550537011823	putative PBP binding loops; other site
550537011824	ABC-ATPase subunit interface; other site
550537011825	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 2.7e-19
550537011826	4 probable transmembrane helices predicted for SEN2334 by TMHMM2.0 at aa 25-47, 57-79, 167-189 and 199-221
550537011827	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537011828	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
550537011829	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537011830	dimer interface [polypeptide binding]; other site
550537011831	conserved gate region; other site
550537011832	putative PBP binding loops; other site
550537011833	ABC-ATPase subunit interface; other site
550537011834	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 5.8e-39
550537011835	5 probable transmembrane helices predicted for SEN2335 by TMHMM2.0 at aa 15-37, 58-80, 90-108, 149-171 and 191-213
550537011836	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011837	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537011838	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
550537011839	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537011840	substrate binding pocket [chemical binding]; other site
550537011841	membrane-bound complex binding site; other site
550537011842	hinge residues; other site
550537011843	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 3.2e-97
550537011844	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537011845	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
550537011846	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537011847	substrate binding pocket [chemical binding]; other site
550537011848	membrane-bound complex binding site; other site
550537011849	hinge residues; other site
550537011850	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 1.2e-91
550537011851	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537011852	1 probable transmembrane helix predicted for SEN2337 by TMHMM2.0 at aa 5-24
550537011853	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
550537011854	Flavoprotein; Region: Flavoprotein; pfam02441
550537011855	HMMPfam hit to PF02441, Flavoprotein, score 8.7e-51
550537011856	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
550537011857	12 probable transmembrane helices predicted for SEN2339 by TMHMM2.0 at aa 25-47, 57-79, 86-108, 128-150, 163-185, 200-222, 243-265, 292-314, 334-356, 366-388, 409-431 and 435-457
550537011858	HMMPfam hit to PF00324, Amino acid permease-associated region, score 5.6e-100
550537011859	PS00017 ATP/GTP-binding site motif A (P-loop).
550537011860	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
550537011861	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
550537011862	dimer interface [polypeptide binding]; other site
550537011863	active site
550537011864	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537011865	substrate binding site [chemical binding]; other site
550537011866	catalytic residue [active]
550537011867	HMMPfam hit to PF01168, Alanine racemase, N-terminal, score 9.1e-15
550537011868	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
550537011869	HMMPfam hit to PF00324, Amino acid permease-associated region, score 2.3e-05
550537011870	12 probable transmembrane helices predicted for SEN2341 by TMHMM2.0 at aa 7-29, 39-61, 82-101, 116-138, 151-173, 193-215, 235-257, 281-303, 332-354, 358-380, 403-425 and 435-457
550537011871	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011872	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
550537011873	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
550537011874	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537011875	catalytic residue [active]
550537011876	HMMPfam hit to PF00278, Orn/DAP/Arg decarboxylase 2, score 1.5e-25
550537011877	HMMPfam hit to PF02784, Orn/DAP/Arg decarboxylase 2, score 3.2e-34
550537011878	PAS fold; Region: PAS_4; pfam08448
550537011879	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
550537011880	putative active site [active]
550537011881	heme pocket [chemical binding]; other site
550537011882	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
550537011883	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537011884	Walker A motif; other site
550537011885	ATP binding site [chemical binding]; other site
550537011886	Walker B motif; other site
550537011887	arginine finger; other site
550537011888	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
550537011889	HMMPfam hit to PF08448, PAS fold-4, score 6.4e-08
550537011890	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 4.5e-119
550537011891	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537011892	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 1.6e-14
550537011893	amidophosphoribosyltransferase; Provisional; Region: PRK09246
550537011894	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
550537011895	active site
550537011896	tetramer interface [polypeptide binding]; other site
550537011897	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537011898	active site
550537011899	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 9.5e-13
550537011900	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
550537011901	HMMPfam hit to PF00310, Glutamine amidotransferase, class-II, score 1e-67
550537011902	PS00443 Glutamine amidotransferases class-II active site.
550537011903	colicin V production protein; Provisional; Region: PRK10845
550537011904	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
550537011905	HMMPfam hit to PF02674, Colicin V production protein, score 4e-60
550537011906	4 probable transmembrane helices predicted for SEN2345 by TMHMM2.0 at aa 4-26, 31-53, 63-85 and 98-120
550537011907	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011908	cell division protein DedD; Provisional; Region: PRK11633
550537011909	Sporulation related domain; Region: SPOR; pfam05036
550537011910	HMMPfam hit to PF05036, Sporulation/cell division region, bacteria, score 6.7e-16
550537011911	1 probable transmembrane helix predicted for SEN2346 by TMHMM2.0 at aa 10-27
550537011912	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
550537011913	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
550537011914	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
550537011915	HMMPfam hit to PF02875, Mur ligase, C-terminal, score 0.0033
550537011916	HMMPfam hit to PF08245, Mur ligase, central, score 2.1e-06
550537011917	PS01012 Folylpolyglutamate synthase signature 2.
550537011918	PS01011 Folylpolyglutamate synthase signature 1.
550537011919	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
550537011920	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
550537011921	HMMPfam hit to PF01039, Carboxyl transferase, score 9.6e-13
550537011922	hypothetical protein; Provisional; Region: PRK10847
550537011923	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
550537011924	4 probable transmembrane helices predicted for SEN2349 by TMHMM2.0 at aa 27-49, 71-93, 158-180 and 190-208
550537011925	HMMPfam hit to PF09335, SNARE associated Golgi protein, score 2.3e-06
550537011926	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
550537011927	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
550537011928	dimerization interface 3.5A [polypeptide binding]; other site
550537011929	active site
550537011930	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 5.2e-31
550537011931	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 3.5e-37
550537011932	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
550537011933	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
550537011934	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisation region, score 1.6e-55
550537011935	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011936	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD - binding, score 8.3e-39
550537011937	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
550537011938	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
550537011939	ligand binding site [chemical binding]; other site
550537011940	NAD binding site [chemical binding]; other site
550537011941	catalytic site [active]
550537011942	homodimer interface [polypeptide binding]; other site
550537011943	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region, score 1.2e-26
550537011944	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding, score 3.6e-29
550537011945	PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
550537011946	PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature.
550537011947	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
550537011948	1 probable transmembrane helix predicted for SEN2353 by TMHMM2.0 at aa 310-332
550537011949	putative transporter; Provisional; Region: PRK12382
550537011950	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537011951	putative substrate translocation pore; other site
550537011952	12 probable transmembrane helices predicted for SEN2354 by TMHMM2.0 at aa 20-42, 52-71, 83-105, 120-142, 149-171, 175-197, 209-231, 246-268, 275-297, 302-324, 337-359 and 369-388
550537011953	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011954	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1e-33
550537011955	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011956	1 probable transmembrane helix predicted for SEN2355A by TMHMM2.0 at aa 88-105
550537011957	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537011958	non-specific DNA binding site [nucleotide binding]; other site
550537011959	salt bridge; other site
550537011960	sequence-specific DNA binding site [nucleotide binding]; other site
550537011961	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 3.8e-06
550537011962	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
550537011963	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011964	CAAX protease self-immunity; Region: Abi; pfam02517
550537011965	7 probable transmembrane helices predicted for SEN2359 by TMHMM2.0 at aa 12-31, 41-63, 75-97, 117-139, 146-163, 168-187 and 194-216
550537011966	HMMPfam hit to PF02517, Abortive infection protein, score 7.9e-15
550537011967	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
550537011968	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
550537011969	dimer interface [polypeptide binding]; other site
550537011970	active site
550537011971	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal, score 2.7e-43
550537011972	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal, score 6.6e-58
550537011973	PS00606 Beta-ketoacyl synthases active site.
550537011974	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011975	Uncharacterized conserved protein [Function unknown]; Region: COG4121
550537011976	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
550537011977	HMMPfam hit to PF05430, Protein of unknown function DUF752, score 1.3e-147
550537011978	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 3.1e-60
550537011979	PS00659 Glycosyl hydrolases family 5 signature.
550537011980	YfcL protein; Region: YfcL; pfam08891
550537011981	HMMPfam hit to PF08891, YfcL protein, score 7.1e-49
550537011982	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
550537011983	HMMPfam hit to PF04315, Protein of unknown function DUF462, score 1.2e-147
550537011984	hypothetical protein; Provisional; Region: PRK10621
550537011985	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
550537011986	8 probable transmembrane helices predicted for SEN2364 by TMHMM2.0 at aa 7-28, 32-54, 85-104, 108-127, 139-158, 163-182, 195-217 and 237-255
550537011987	HMMPfam hit to PF01925, Protein of unknown function DUF81, score 3.6e-62
550537011988	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537011989	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
550537011990	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
550537011991	HMMPfam hit to PF03411, Peptidase M74, penicillin-insensitive murein endopeptidase, score 4.1e-195
550537011992	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
550537011993	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
550537011994	Tetramer interface [polypeptide binding]; other site
550537011995	active site
550537011996	FMN-binding site [chemical binding]; other site
550537011997	HMMPfam hit to PF01264, Chorismate synthase, score 3.3e-236
550537011998	PS00789 Chorismate synthase signature 3.
550537011999	PS00788 Chorismate synthase signature 2.
550537012000	PS00787 Chorismate synthase signature 1.
550537012001	HemK family putative methylases; Region: hemK_fam; TIGR00536
550537012002	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537012003	S-adenosylmethionine binding site [chemical binding]; other site
550537012004	PS00092 N-6 Adenine-specific DNA methylases signature.
550537012005	HMMPfam hit to PF08242, Methyltransferase type 12, score 3.6e-07
550537012006	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012007	hypothetical protein; Provisional; Region: PRK04946
550537012008	Smr domain; Region: Smr; pfam01713
550537012009	HMMPfam hit to PF01713, Smr protein/MutS2 C-terminal, score 8.7e-33
550537012010	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
550537012011	catalytic core [active]
550537012012	HMMPfam hit to PF00300, Phosphoglycerate mutase, score 5.7e-12
550537012013	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
550537012014	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
550537012015	substrate binding site [chemical binding]; other site
550537012016	oxyanion hole (OAH) forming residues; other site
550537012017	trimer interface [polypeptide binding]; other site
550537012018	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
550537012019	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
550537012020	HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 5.3e-42
550537012021	PS00067 3-hydroxyacyl-CoA dehydrogenase signature.
550537012022	HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD-binding, score 2.5e-83
550537012023	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012024	HMMPfam hit to PF00378, Crotonase, core, score 1.1e-64
550537012025	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
550537012026	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
550537012027	dimer interface [polypeptide binding]; other site
550537012028	active site
550537012029	HMMPfam hit to PF02803, Thiolase, score 1.8e-57
550537012030	PS00099 Thiolases active site.
550537012031	PS00737 Thiolases signature 2.
550537012032	HMMPfam hit to PF00108, Thiolase, score 2.5e-63
550537012033	PS00098 Thiolases acyl-enzyme intermediate signature.
550537012034	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
550537012035	HMMPfam hit to PF04175, Conserved hypothetical protein CHP00743, score 1.4e-60
550537012036	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
550537012037	HMMPfam hit to PF03349, Membrane protein involved in aromatic hydrocarbon degradation, score 2.5e-191
550537012038	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
550537012039	HMMPfam hit to PF04333, VacJ-like lipoprotein, score 1.2e-119
550537012040	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012041	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
550537012042	6 probable transmembrane helices predicted for SEN2375 by TMHMM2.0 at aa 62-84, 94-116, 137-159, 190-209, 216-235 and 255-277
550537012043	prophage remnant carrying O-chain modification proteins; Salmonella pathogenicity island 17: SPI-17
550537012045	HMMPfam hit to PF00872, Transposase, mutator type, score 3e-23
550537012047	Predicted membrane protein [Function unknown]; Region: COG2246
550537012048	GtrA-like protein; Region: GtrA; pfam04138
550537012049	HMMPfam hit to PF04138, GtrA-like protein, score 9.5e-24
550537012050	3 probable transmembrane helices predicted for SEN2376 by TMHMM2.0 at aa 30-52, 65-84 and 94-116
550537012051	Notes appears to have been subject to a deletion event removing the majority of the 3' region of the CDS
550537012052	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 6.2e-11
550537012053	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
550537012054	HMMPfam hit to PF01757, Acyltransferase 3, score 1.1e-67
550537012055	11 probable transmembrane helices predicted for SEN2378 by TMHMM2.0 at aa 13-35, 40-59, 72-94, 134-156, 168-186, 201-218, 225-242, 246-268, 275-297, 312-333 and 345-367
550537012056	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012057	1 probable transmembrane helix predicted for SEN2379 by TMHMM2.0 at aa 34-56
550537012058	Notes appears to have been subject to a deletion event removing the majority of the 3' region of the CDS
550537012060	HMMPfam hit to PF09251, Bacteriophage P22, tailspike, score 1.9e-49
550537012061	outer membrane protease; Reviewed; Region: PRK10993
550537012062	HMMPfam hit to PF01278, Peptidase A26, omptin, score 4e-219
550537012063	PS00835 Serine proteases, omptin family signature 2.
550537012064	PS00834 Serine proteases, omptin family signature 1.
550537012065	PS00018 EF-hand calcium-binding domain.
550537012066	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
550537012067	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537012068	active site
550537012069	phosphorylation site [posttranslational modification]
550537012070	intermolecular recognition site; other site
550537012071	dimerization interface [polypeptide binding]; other site
550537012072	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
550537012073	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
550537012074	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 7.5e-15
550537012075	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537012076	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 5.2e-12
550537012077	HMMPfam hit to PF00072, Response regulator receiver, score 2.5e-40
550537012078	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
550537012079	HAMP domain; Region: HAMP; pfam00672
550537012080	dimerization interface [polypeptide binding]; other site
550537012081	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537012082	dimer interface [polypeptide binding]; other site
550537012083	phosphorylation site [posttranslational modification]
550537012084	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537012085	ATP binding site [chemical binding]; other site
550537012086	Mg2+ binding site [ion binding]; other site
550537012087	G-X-G motif; other site
550537012088	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.5e-25
550537012089	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 6.4e-08
550537012090	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 6.2e-11
550537012091	2 probable transmembrane helices predicted for SEN2383 by TMHMM2.0 at aa 20-39 and 335-357
550537012092	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
550537012093	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
550537012094	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 5.5e-06
550537012095	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
550537012096	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537012097	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537012098	12 probable transmembrane helices predicted for SEN2385 by TMHMM2.0 at aa 21-43, 63-85, 98-120, 124-146, 158-180, 190-207, 260-282, 297-315, 327-344, 348-370, 377-399 and 414-436
550537012099	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 2.2e-46
550537012100	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012101	PS00942 glpT family of transporters signature.
550537012102	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012103	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
550537012104	3 probable transmembrane helices predicted for SEN2386 by TMHMM2.0 at aa 2-24, 29-48 and 55-77
550537012105	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
550537012106	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
550537012107	putative acyl-acceptor binding pocket; other site
550537012108	HMMPfam hit to PF03279, Bacterial lipid A biosynthesis acyltransferase, score 3.9e-147
550537012109	1 probable transmembrane helix predicted for SEN2387 by TMHMM2.0 at aa 20-42
550537012110	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537012111	aminotransferase; Validated; Region: PRK08175
550537012112	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537012113	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537012114	homodimer interface [polypeptide binding]; other site
550537012115	catalytic residue [active]
550537012116	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 3.1e-63
550537012117	glucokinase; Provisional; Region: glk; PRK00292
550537012118	glucokinase, proteobacterial type; Region: glk; TIGR00749
550537012119	HMMPfam hit to PF02685, Glucokinase, score 1.8e-189
550537012120	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
550537012121	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
550537012122	Cl- selectivity filter; other site
550537012123	Cl- binding residues [ion binding]; other site
550537012124	pore gating glutamate residue; other site
550537012125	dimer interface [polypeptide binding]; other site
550537012126	11 probable transmembrane helices predicted for SEN2390 by TMHMM2.0 at aa 9-31, 57-74, 95-117, 148-170, 186-208, 223-245, 258-280, 295-317, 322-341, 345-363 and 376-398
550537012127	HMMPfam hit to PF00654, Chloride channel, core, score 2.3e-05
550537012128	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
550537012129	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
550537012130	dimer interface [polypeptide binding]; other site
550537012131	PYR/PP interface [polypeptide binding]; other site
550537012132	TPP binding site [chemical binding]; other site
550537012133	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
550537012134	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
550537012135	TPP-binding site [chemical binding]; other site
550537012136	dimer interface [polypeptide binding]; other site
550537012137	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding, score 5.3e-18
550537012138	PS00187 Thiamine pyrophosphate enzymes signature.
550537012139	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central region, score 9.4e-16
550537012140	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding region, score 3.4e-76
550537012141	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
550537012142	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537012143	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537012144	active site
550537012145	catalytic tetrad [active]
550537012146	HMMPfam hit to PF00248, Aldo/keto reductase, score 2.5e-62
550537012147	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
550537012148	1 probable transmembrane helix predicted for SEN2393 by TMHMM2.0 at aa 5-27
550537012149	manganese transport protein MntH; Reviewed; Region: PRK00701
550537012150	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
550537012151	11 probable transmembrane helices predicted for SEN2394 by TMHMM2.0 at aa 17-39, 54-76, 96-118, 123-145, 157-176, 196-218, 239-261, 281-303, 324-343, 348-370 and 390-412
550537012152	HMMPfam hit to PF01566, Natural resistance-associated macrophage protein, score 4.9e-197
550537012153	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
550537012154	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
550537012155	Nucleoside recognition; Region: Gate; pfam07670
550537012156	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
550537012157	HMMPfam hit to PF01773, Na+ dependent nucleoside transporter, score 2.7e-33
550537012158	8 probable transmembrane helices predicted for SEN2395 by TMHMM2.0 at aa 4-23, 30-48, 86-108, 194-216, 249-271, 278-300, 342-364 and 377-399
550537012159	HMMPfam hit to PF07670, Nucleoside recognition, score 1.8e-18
550537012160	HMMPfam hit to PF07662, Na+ dependent nucleoside transporter, C-terminal, score 2.7e-107
550537012161	MASE1; Region: MASE1; pfam05231
550537012162	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
550537012163	diguanylate cyclase; Region: GGDEF; smart00267
550537012164	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537012165	HMMPfam hit to PF00563, EAL, score 9.7e-94
550537012166	HMMPfam hit to PF00990, GGDEF, score 0.00016
550537012167	HMMPfam hit to PF05231, MASE1, score 1.6e-73
550537012168	8 probable transmembrane helices predicted for SEN2396 by TMHMM2.0 at aa 10-32, 39-61, 86-108, 121-143, 163-185, 214-236, 246-268 and 289-311
550537012169	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
550537012170	HMMPfam hit to PF07037, Protein of unknown function DUF1323, score 7.7e-81
550537012171	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
550537012172	HMMPfam hit to PF07037, Protein of unknown function DUF1323, score 5.8e-91
550537012173	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
550537012174	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
550537012175	active site
550537012176	HIGH motif; other site
550537012177	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
550537012178	active site
550537012179	KMSKS motif; other site
550537012180	HMMPfam hit to PF00749, Glutamyl/glutaminyl-tRNA synthetase, class Ic, score 1.2e-182
550537012181	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537012182	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
550537012183	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537012184	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
550537012185	putative dimerization interface [polypeptide binding]; other site
550537012186	putative substrate binding pocket [chemical binding]; other site
550537012187	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.2e-39
550537012188	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 9.6e-20
550537012189	PS00044 Bacterial regulatory proteins, lysR family signature.
550537012190	2 probable transmembrane helices predicted for SEN2401 by TMHMM2.0 at aa 5-26 and 30-47
550537012191	nucleoside transporter; Region: 2A0110; TIGR00889
550537012192	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537012193	putative substrate translocation pore; other site
550537012194	HMMPfam hit to PF03825, Nucleoside:H+ symporter, score 3.5e-285
550537012195	12 probable transmembrane helices predicted for SEN2402 by TMHMM2.0 at aa 12-30, 40-62, 71-90, 94-116, 128-150, 160-179, 211-233, 253-275, 282-301, 306-328, 348-370 and 380-402
550537012196	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012197	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012198	purine nucleoside phosphorylase; Provisional; Region: PRK08202
550537012199	HMMPfam hit to PF00896, Purine phosphorylase, family 2, score 3.3e-127
550537012200	hypothetical protein; Provisional; Region: PRK11528
550537012201	HMMPfam hit to PF07135, Protein of unknown function DUF1384, score 2.5e-179
550537012202	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537012203	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537012204	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
550537012205	putative dimerization interface [polypeptide binding]; other site
550537012206	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.4e-48
550537012207	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 3.5e-23
550537012208	PS00044 Bacterial regulatory proteins, lysR family signature.
550537012209	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
550537012210	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
550537012211	9 probable transmembrane helices predicted for SEN2406 by TMHMM2.0 at aa 7-24, 29-48, 69-91, 101-123, 130-152, 167-189, 202-224, 229-251 and 272-294
550537012212	HMMPfam hit to PF01758, Bile acid:sodium symporter, score 0.0007
550537012213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
550537012214	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
550537012215	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
550537012216	nucleotide binding pocket [chemical binding]; other site
550537012217	K-X-D-G motif; other site
550537012218	catalytic site [active]
550537012219	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
550537012220	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
550537012221	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
550537012222	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
550537012223	Dimer interface [polypeptide binding]; other site
550537012224	BRCT sequence motif; other site
550537012225	HMMPfam hit to PF00533, BRCT, score 1.4e-19
550537012226	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 1.6e-06
550537012227	HMMPfam hit to PF03119, Zinc-finger, NAD-dependent DNA ligase C4-type, score 5.2e-13
550537012228	HMMPfam hit to PF03120, NAD-dependent DNA ligase, OB-fold, score 1.5e-53
550537012229	PS01056 NAD-dependent DNA ligase signature 2.
550537012230	HMMPfam hit to PF01653, NAD-dependent DNA ligase, adenylation, score 8.5e-212
550537012231	PS01055 NAD-dependent DNA ligase signature 1.
550537012232	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
550537012233	cell division protein ZipA; Provisional; Region: PRK03427
550537012234	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
550537012235	FtsZ protein binding site [polypeptide binding]; other site
550537012236	HMMPfam hit to PF04354, ZipA, C-terminal FtsZ-binding region, score 4.7e-90
550537012237	1 probable transmembrane helix predicted for SEN2409 by TMHMM2.0 at aa 5-27
550537012238	putative sulfate transport protein CysZ; Validated; Region: PRK04949
550537012239	4 probable transmembrane helices predicted for SEN2410 by TMHMM2.0 at aa 31-53, 68-90, 151-173 and 220-242
550537012240	HMMPfam hit to PF04401, Protein of unknown function DUF540, score 1.2e-109
550537012241	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
550537012242	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
550537012243	dimer interface [polypeptide binding]; other site
550537012244	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537012245	catalytic residue [active]
550537012246	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 2e-126
550537012247	PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
550537012248	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
550537012249	dimerization domain swap beta strand [polypeptide binding]; other site
550537012250	regulatory protein interface [polypeptide binding]; other site
550537012251	active site
550537012252	regulatory phosphorylation site [posttranslational modification]; other site
550537012253	HMMPfam hit to PF00381, Phosphotransferase system, phosphocarrier HPr protein, score 5.7e-49
550537012254	PS00369 PTS HPR component histidine phosphorylation site signature.
550537012255	PS00589 PTS HPR component serine phosphorylation site signature.
550537012256	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
550537012257	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
550537012258	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
550537012259	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
550537012260	HMMPfam hit to PF05524, Phosphotransferase system, PEP-utilising enzyme, N-terminal, score 4.7e-60
550537012261	HMMPfam hit to PF00391, PEP-utilising enzyme, mobile region, score 2.6e-37
550537012262	PS00370 PEP-utilizing enzymes phosphorylation site signature.
550537012263	HMMPfam hit to PF02896, PEP-utilizing enzyme, score 1.3e-193
550537012264	PS00742 PEP-utilizing enzymes signature 2.
550537012265	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
550537012266	HPr interaction site; other site
550537012267	glycerol kinase (GK) interaction site [polypeptide binding]; other site
550537012268	active site
550537012269	phosphorylation site [posttranslational modification]
550537012270	HMMPfam hit to PF00358, Phosphotransferase system, sugar-specific permease EIIA 1 domain, score 3.7e-81
550537012271	PS00371 PTS EIIA domains phosphorylation site signature 1.
550537012272	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537012273	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
550537012274	dimer interface [polypeptide binding]; other site
550537012275	pyridoxamine kinase; Validated; Region: PRK05756
550537012276	pyridoxal binding site [chemical binding]; other site
550537012277	ATP binding site [chemical binding]; other site
550537012278	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 1.6e-05
550537012279	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
550537012280	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537012281	DNA-binding site [nucleotide binding]; DNA binding site
550537012282	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537012283	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537012284	homodimer interface [polypeptide binding]; other site
550537012285	catalytic residue [active]
550537012286	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 4.8e-24
550537012287	PS00043 Bacterial regulatory proteins, gntR family signature.
550537012288	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 2.5e-08
550537012289	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
550537012290	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
550537012291	catalytic triad [active]
550537012292	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 9.9e-06
550537012293	hypothetical protein; Provisional; Region: PRK10318
550537012294	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537012295	Sel1-like repeats; Region: SEL1; smart00671
550537012296	HMMPfam hit to PF08238, Sel1-like, score 0.85
550537012297	HMMPfam hit to PF08238, Sel1-like, score 0.73
550537012298	HMMPfam hit to PF08238, Sel1-like, score 4.4e-11
550537012299	cysteine synthase B; Region: cysM; TIGR01138
550537012300	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
550537012301	dimer interface [polypeptide binding]; other site
550537012302	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537012303	catalytic residue [active]
550537012304	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 4.2e-112
550537012305	PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
550537012306	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
550537012307	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
550537012308	Walker A/P-loop; other site
550537012309	ATP binding site [chemical binding]; other site
550537012310	Q-loop/lid; other site
550537012311	ABC transporter signature motif; other site
550537012312	Walker B; other site
550537012313	D-loop; other site
550537012314	H-loop/switch region; other site
550537012315	TOBE-like domain; Region: TOBE_3; pfam12857
550537012316	HMMPfam hit to PF00005, ABC transporter related, score 1.2e-68
550537012317	PS00211 ABC transporters family signature.
550537012318	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012319	sulfate transport protein; Provisional; Region: cysT; CHL00187
550537012320	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537012321	dimer interface [polypeptide binding]; other site
550537012322	conserved gate region; other site
550537012323	putative PBP binding loops; other site
550537012324	ABC-ATPase subunit interface; other site
550537012325	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 2.7e-16
550537012326	6 probable transmembrane helices predicted for SEN2423 by TMHMM2.0 at aa 21-43, 66-88, 101-123, 143-162, 201-223 and 246-268
550537012327	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537012328	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
550537012329	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537012330	dimer interface [polypeptide binding]; other site
550537012331	conserved gate region; other site
550537012332	putative PBP binding loops; other site
550537012333	ABC-ATPase subunit interface; other site
550537012334	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 5.8e-37
550537012335	7 probable transmembrane helices predicted for SEN2424 by TMHMM2.0 at aa 15-37, 62-84, 104-126, 138-160, 188-205, 212-234 and 244-266
550537012336	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537012337	thiosulfate transporter subunit; Provisional; Region: PRK10852
550537012338	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
550537012339	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 4.3e-11
550537012340	PS00757 Prokaryotic sulfate-binding proteins signature 2.
550537012341	PS00401 Prokaryotic sulfate-binding proteins signature 1.
550537012342	PS00092 N-6 Adenine-specific DNA methylases signature.
550537012343	short chain dehydrogenase; Provisional; Region: PRK08226
550537012344	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
550537012345	NAD binding site [chemical binding]; other site
550537012346	homotetramer interface [polypeptide binding]; other site
550537012347	homodimer interface [polypeptide binding]; other site
550537012348	active site
550537012349	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 3.6e-40
550537012350	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
550537012351	HMMPfam hit to PF04261, Dyp-type peroxidase, score 1.1e-159
550537012352	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
550537012353	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
550537012354	HMMPfam hit to PF06572, Protein of unknown function DUF1131, score 3.9e-167
550537012355	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012356	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
550537012357	4 probable transmembrane helices predicted for SEN2429 by TMHMM2.0 at aa 19-41, 61-78, 90-112 and 116-135
550537012358	putative acetyltransferase; Provisional; Region: PRK03624
550537012359	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537012360	Coenzyme A binding pocket [chemical binding]; other site
550537012361	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 4.6e-22
550537012362	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
550537012363	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
550537012364	active site
550537012365	metal binding site [ion binding]; metal-binding site
550537012366	HMMPfam hit to PF01520, Cell wall hydrolase/autolysin, catalytic, score 7.2e-108
550537012367	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
550537012368	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
550537012369	HMMPfam hit to PF01218, Coproporphyrinogen III oxidase, score 1.8e-241
550537012370	PS01021 Coproporphyrinogen III oxidase signature.
550537012371	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012372	3 probable transmembrane helices predicted for SEN2433 by TMHMM2.0 at aa 19-36, 51-73 and 86-108
550537012373	transcriptional regulator EutR; Provisional; Region: PRK10130
550537012374	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537012375	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537012376	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.00012
550537012377	PS00041 Bacterial regulatory proteins, araC family signature.
550537012378	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 3.2e-10
550537012379	carboxysome structural protein EutK; Provisional; Region: PRK15466
550537012380	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
550537012381	Hexamer interface [polypeptide binding]; other site
550537012382	Hexagonal pore residue; other site
550537012383	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 7.4e-30
550537012384	PS01139 Bacterial microcompartiments proteins signature.
550537012385	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
550537012386	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
550537012387	putative hexamer interface [polypeptide binding]; other site
550537012388	putative hexagonal pore; other site
550537012389	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
550537012390	putative hexamer interface [polypeptide binding]; other site
550537012391	putative hexagonal pore; other site
550537012392	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 4.1e-12
550537012393	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
550537012394	HMMPfam hit to PF05985, Ethanolamine ammonia-lyase light chain, score 3.9e-152
550537012395	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
550537012396	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
550537012397	HMMPfam hit to PF06751, Ethanolamine ammonia lyase large subunit, score 0
550537012398	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012399	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012400	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
550537012401	HMMPfam hit to PF06277, Ethanolamine utilisation EutA, score 0
550537012402	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
550537012403	HMMPfam hit to PF04346, Ethanolamine utilisation protein, EutH, score 4.6e-280
550537012404	10 probable transmembrane helices predicted for SEN2440 by TMHMM2.0 at aa 7-29, 58-80, 87-109, 124-146, 153-175, 190-212, 231-253, 273-295, 308-330 and 370-392
550537012405	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012406	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
550537012407	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
550537012408	active site
550537012409	metal binding site [ion binding]; metal-binding site
550537012410	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 9.1e-207
550537012411	PS00060 Iron-containing alcohol dehydrogenases signature 2.
550537012412	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012413	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537012414	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012415	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
550537012416	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537012417	nucleotide binding site [chemical binding]; other site
550537012418	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
550537012419	putative catalytic cysteine [active]
550537012420	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 1e-10
550537012421	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
550537012422	Hexamer/Pentamer interface [polypeptide binding]; other site
550537012423	central pore; other site
550537012424	HMMPfam hit to PF03319, Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, score 3.3e-50
550537012425	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
550537012426	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
550537012427	Hexamer interface [polypeptide binding]; other site
550537012428	Putative hexagonal pore residue; other site
550537012429	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 2.5e-40
550537012430	PS01139 Bacterial microcompartiments proteins signature.
550537012431	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
550537012432	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 1.4e-168
550537012433	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
550537012434	HMMPfam hit to PF01923, Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, score 1.4e-46
550537012435	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
550537012436	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
550537012437	HMMPfam hit to PF06249, Ethanolamine utilisation EutQ, score 2.7e-104
550537012438	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012439	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
550537012440	G1 box; other site
550537012441	GTP/Mg2+ binding site [chemical binding]; other site
550537012442	G2 box; other site
550537012443	Switch I region; other site
550537012444	G3 box; other site
550537012445	Switch II region; other site
550537012446	G4 box; other site
550537012447	G5 box; other site
550537012448	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012449	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
550537012450	putative hexamer interface [polypeptide binding]; other site
550537012451	putative hexagonal pore; other site
550537012452	HMMPfam hit to PF00936, Bacterial microcompartments protein, score 2.7e-16
550537012453	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
550537012454	Malic enzyme, N-terminal domain; Region: malic; pfam00390
550537012455	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
550537012456	putative NAD(P) binding site [chemical binding]; other site
550537012457	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
550537012458	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 9.2e-116
550537012459	HMMPfam hit to PF03949, Malic enzyme, NAD-binding, score 1.4e-127
550537012460	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012461	HMMPfam hit to PF00390, Malic enzyme, N-terminal, score 6e-78
550537012462	transaldolase-like protein; Provisional; Region: PTZ00411
550537012463	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
550537012464	active site
550537012465	dimer interface [polypeptide binding]; other site
550537012466	catalytic residue [active]
550537012467	HMMPfam hit to PF00923, Transaldolase, score 1.5e-181
550537012468	PS01054 Transaldolase signature 1.
550537012469	transketolase; Reviewed; Region: PRK12753
550537012470	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
550537012471	TPP-binding site [chemical binding]; other site
550537012472	dimer interface [polypeptide binding]; other site
550537012473	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
550537012474	PYR/PP interface [polypeptide binding]; other site
550537012475	dimer interface [polypeptide binding]; other site
550537012476	TPP binding site [chemical binding]; other site
550537012477	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
550537012478	HMMPfam hit to PF00456, Transketolase, N-terminal, score 3.3e-258
550537012479	PS00801 Transketolase signature 1.
550537012480	HMMPfam hit to PF02779, Transketolase, central region, score 1.1e-71
550537012481	PS00802 Transketolase signature 2.
550537012482	HMMPfam hit to PF02780, Transketolase, C-terminal, score 1.8e-14
550537012483	PS00190 Cytochrome c family heme-binding site signature.
550537012484	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
550537012485	HMMPfam hit to PF06674, Protein of unknown function DUF1176, score 6.2e-213
550537012486	1 probable transmembrane helix predicted for SEN2455 by TMHMM2.0 at aa 5-24
550537012487	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
550537012488	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
550537012489	dimer interface [polypeptide binding]; other site
550537012490	ADP-ribose binding site [chemical binding]; other site
550537012491	active site
550537012492	nudix motif; other site
550537012493	metal binding site [ion binding]; metal-binding site
550537012494	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 9.3e-19
550537012495	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012496	putative periplasmic esterase; Provisional; Region: PRK03642
550537012497	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
550537012498	HMMPfam hit to PF00144, Beta-lactamase, score 8.9e-70
550537012499	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
550537012500	4Fe-4S binding domain; Region: Fer4; pfam00037
550537012501	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
550537012502	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537012503	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 6.4e-20
550537012504	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 0.0035
550537012505	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012506	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 1e-06
550537012507	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012508	PS00430 TonB-dependent receptor proteins signature 1.
550537012509	PS00190 Cytochrome c family heme-binding site signature.
550537012510	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
550537012511	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
550537012512	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537012513	dimerization interface [polypeptide binding]; other site
550537012514	Histidine kinase; Region: HisKA_3; pfam07730
550537012515	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537012516	ATP binding site [chemical binding]; other site
550537012517	Mg2+ binding site [ion binding]; other site
550537012518	G-X-G motif; other site
550537012519	2 probable transmembrane helices predicted for SEN2459 by TMHMM2.0 at aa 15-37 and 147-169
550537012520	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 3e-13
550537012521	HMMPfam hit to PF07730, Histidine kinase, dimerisation and phosphoacceptor region, score 2.3e-19
550537012522	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 4.4e-21
550537012523	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
550537012524	Protein export membrane protein; Region: SecD_SecF; cl14618
550537012525	HMMPfam hit to PF00873, Acriflavin resistance protein, score 0
550537012526	11 probable transmembrane helices predicted for SEN2460 by TMHMM2.0 at aa 10-32, 337-359, 364-386, 438-460, 470-492, 538-560, 868-890, 897-919, 924-946, 972-994 and 1004-1026
550537012527	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
550537012528	ArsC family; Region: ArsC; pfam03960
550537012529	putative catalytic residues [active]
550537012530	HMMPfam hit to PF03960, Arsenate reductase and related, score 2.1e-45
550537012531	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
550537012532	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
550537012533	metal binding site [ion binding]; metal-binding site
550537012534	dimer interface [polypeptide binding]; other site
550537012535	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
550537012536	HMMPfam hit to PF01546, Peptidase M20, score 1.9e-53
550537012537	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
550537012538	HMMPfam hit to PF07687, Peptidase M20, dimerisation, score 3.3e-35
550537012539	hypothetical protein; Provisional; Region: PRK13664
550537012540	1 probable transmembrane helix predicted for SEN2463 by TMHMM2.0 at aa 5-24
550537012541	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
550537012542	Helicase; Region: Helicase_RecD; pfam05127
550537012543	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
550537012544	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
550537012545	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 0.0004
550537012546	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012547	HMMPfam hit to PF05127, Protein of unknown function DUF699, ATPase , score 6.2e-51
550537012548	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012549	Predicted metalloprotease [General function prediction only]; Region: COG2321
550537012550	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
550537012551	HMMPfam hit to PF04228, Protein of unknown function, zinc metallopeptidase , score 2.5e-243
550537012552	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537012553	1 probable transmembrane helix predicted for SEN2465 by TMHMM2.0 at aa 38-60
550537012554	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
550537012555	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
550537012556	ATP binding site [chemical binding]; other site
550537012557	active site
550537012558	substrate binding site [chemical binding]; other site
550537012559	HMMPfam hit to PF01259, SAICAR synthetase, score 4.7e-123
550537012560	PS01058 SAICAR synthetase signature 2.
550537012561	PS01057 SAICAR synthetase signature 1.
550537012562	lipoprotein; Provisional; Region: PRK11679
550537012563	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
550537012564	HMMPfam hit to PF06804, NlpBDapX lipoprotein, score 5.7e-197
550537012565	PS00572 Glycosyl hydrolases family 1 active site.
550537012566	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012567	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
550537012568	dihydrodipicolinate synthase; Region: dapA; TIGR00674
550537012569	dimer interface [polypeptide binding]; other site
550537012570	active site
550537012571	catalytic residue [active]
550537012572	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase, score 5.2e-172
550537012573	PS00666 Dihydrodipicolinate synthetase signature 2.
550537012574	PS00665 Dihydrodipicolinate synthetase signature 1.
550537012575	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
550537012576	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
550537012577	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
550537012578	HMMPfam hit to PF01842, Amino acid-binding ACT, score 7.5e-05
550537012579	HMMPfam hit to PF01842, Amino acid-binding ACT, score 0.012
550537012580	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
550537012581	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
550537012582	catalytic triad [active]
550537012583	HMMPfam hit to PF00578, Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen, score 8.3e-50
550537012584	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012585	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
550537012586	HMMPfam hit to PF02595, Glycerate kinase, score 6.8e-225
550537012587	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
550537012588	fructuronate transporter; Provisional; Region: PRK10034; cl15264
550537012589	11 probable transmembrane helices predicted for SEN2472 by TMHMM2.0 at aa 5-27, 34-56, 71-93, 106-128, 179-201, 222-244, 249-268, 281-303, 313-335, 348-370 and 409-428
550537012590	HMMPfam hit to PF03600, Divalent ion symporter, score 1.2e-07
550537012591	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
550537012592	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
550537012593	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
550537012594	HMMPfam hit to PF05651,  sugar diacid recognition, score 1.4e-121
550537012595	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
550537012596	Domain of unknown function DUF20; Region: UPF0118; pfam01594
550537012597	HMMPfam hit to PF01594, Protein of unknown function UPF0118, score 4.4e-104
550537012598	7 probable transmembrane helices predicted for SEN2474 by TMHMM2.0 at aa 20-51, 71-93, 155-177, 217-236, 251-273, 278-300 and 310-332
550537012599	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
550537012600	Peptidase family M48; Region: Peptidase_M48; cl12018
550537012601	HMMPfam hit to PF01435, Peptidase M48, Ste24p, score 7.1e-30
550537012602	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
550537012603	ArsC family; Region: ArsC; pfam03960
550537012604	catalytic residues [active]
550537012605	HMMPfam hit to PF03960, Arsenate reductase and related, score 6e-45
550537012606	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
550537012607	DNA replication initiation factor; Provisional; Region: PRK08084
550537012608	HMMPfam hit to PF00308, Chromosomal replication initiator, DnaA, score 1.8e-06
550537012609	uracil transporter; Provisional; Region: PRK10720
550537012610	12 probable transmembrane helices predicted for SEN2478 by TMHMM2.0 at aa 13-35, 39-61, 68-85, 89-108, 121-143, 158-180, 185-207, 227-249, 304-326, 331-353, 365-387 and 392-411
550537012611	HMMPfam hit to PF00860, Xanthine/uracil/vitamin C permease, score 1e-143
550537012612	PS01116 Xanthine/uracil permeases family signature.
550537012613	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012614	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537012615	active site
550537012616	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 4.7e-13
550537012617	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
550537012618	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
550537012619	dimerization interface [polypeptide binding]; other site
550537012620	putative ATP binding site [chemical binding]; other site
550537012621	HMMPfam hit to PF00586, AIR synthase related protein, score 6.1e-74
550537012622	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal, score 6.8e-50
550537012623	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
550537012624	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
550537012625	active site
550537012626	substrate binding site [chemical binding]; other site
550537012627	cosubstrate binding site; other site
550537012628	catalytic site [active]
550537012629	HMMPfam hit to PF00551, Formyl transferase, N-terminal, score 6.6e-88
550537012630	PS00373 Phosphoribosylglycinamide formyltransferase active site.
550537012631	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
550537012632	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
550537012633	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
550537012634	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
550537012635	putative active site [active]
550537012636	catalytic site [active]
550537012637	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
550537012638	domain interface [polypeptide binding]; other site
550537012639	active site
550537012640	catalytic site [active]
550537012641	HMMPfam hit to PF02503, Polyphosphate kinase, score 0
550537012642	exopolyphosphatase; Provisional; Region: PRK10854
550537012643	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537012644	nucleotide binding site [chemical binding]; other site
550537012645	HMMPfam hit to PF02541, Ppx/GppA phosphatase, score 3.9e-139
550537012646	MASE1; Region: MASE1; pfam05231
550537012647	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
550537012648	diguanylate cyclase; Region: GGDEF; smart00267
550537012649	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537012650	HMMPfam hit to PF00563, EAL, score 3.5e-108
550537012651	HMMPfam hit to PF05231, MASE1, score 7.5e-82
550537012652	8 probable transmembrane helices predicted for SEN2484 by TMHMM2.0 at aa 15-37, 44-66, 81-103, 124-146, 166-188, 216-238, 253-275 and 295-317
550537012653	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
550537012654	HMMPfam hit to PF07377, Protein of unknown function DUF1493, score 2.6e-67
550537012655	Integrase core domain; Region: rve; pfam00665
550537012656	HMMPfam hit to PF00665, Asv integrase core domain, score 1.4e-07
550537012657	HMMPfam hit to PF00665, Integrase, catalytic core, score 2.6e-20
550537012658	GMP synthase; Reviewed; Region: guaA; PRK00074
550537012659	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
550537012660	AMP/PPi binding site [chemical binding]; other site
550537012661	candidate oxyanion hole; other site
550537012662	catalytic triad [active]
550537012663	potential glutamine specificity residues [chemical binding]; other site
550537012664	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
550537012665	ATP Binding subdomain [chemical binding]; other site
550537012666	Ligand Binding sites [chemical binding]; other site
550537012667	Dimerization subdomain; other site
550537012668	HMMPfam hit to PF00958, GMP synthase, C-terminal, score 3.5e-60
550537012669	HMMPfam hit to PF03054, tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase, score 7.3e-10
550537012670	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 1.4e-51
550537012671	PS00442 Glutamine amidotransferases class-I active site.
550537012672	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
550537012673	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
550537012674	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
550537012675	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
550537012676	active site
550537012677	HMMPfam hit to PF00478, IMP dehydrogenase/GMP reductase, score 6e-247
550537012678	PS00487 IMP dehydrogenase / GMP reductase signature.
550537012679	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 4.3e-24
550537012680	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
550537012681	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
550537012682	generic binding surface II; other site
550537012683	generic binding surface I; other site
550537012684	HMMPfam hit to PF01336, Nucleic acid binding, OB-fold, tRNA/helicase-type, score 3.3e-14
550537012685	HMMPfam hit to PF02601, Exonuclease VII, large subunit, score 4.2e-94
550537012686	AIDA autotransporter-like protein ShdA; Provisional; Region: PRK15319
550537012687	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
550537012688	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
550537012689	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
550537012690	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
550537012691	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
550537012692	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
550537012693	Autotransporter beta-domain; Region: Autotransporter; smart00869
550537012694	HMMPfam hit to PF03797, Autotransporter beta-domain, score 2e-33
550537012695	HMMPfam hit to PF03212, Pertactin, score 0.001
550537012696	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012697	HMMPfam hit to PF05594, Filamentous haemagglutinin, bacterial, score 2.2
550537012698	HMMPfam hit to PF05594, Filamentous haemagglutinin, bacterial, score 1.2
550537012699	PS00584 pfkB family of carbohydrate kinases signature 2.
550537012700	Note the premature stop codon following codon 1744
550537012701	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 2.6e-92
550537012702	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 3.2e-17
550537012703	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 3.9e-112
550537012704	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 4.8e-27
550537012705	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 6.3e-98
550537012706	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 7.4e-11
550537012707	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 9.1e-107
550537012708	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 1.2e-27
550537012709	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 3.7e-102
550537012710	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 5.7e-15
550537012711	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 6.8e-94
550537012712	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 1.6e-92
550537012713	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 4e-93
550537012714	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 7.6e-30
550537012715	outer membrane protein RatA; Provisional; Region: PRK15315
550537012716	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
550537012717	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
550537012718	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
550537012719	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
550537012720	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
550537012721	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
550537012722	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
550537012723	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
550537012724	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
550537012725	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
550537012726	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
550537012727	PS00294 Prenyl group binding site (CAAX box).
550537012728	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 9e-84
550537012729	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 4.3e-13
550537012730	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 4.3e-108
550537012731	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 2.5e-21
550537012732	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 2.2e-96
550537012733	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 1e-17
550537012734	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 6.4e-90
550537012735	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 3.7e-87
550537012736	HMMPfam hit to PF05689, Protein of unknown function DUF823, score 9.2e-90
550537012737	HMMPfam hit to PF05688, Protein of unknown function DUF824, score 7.2e-27
550537012738	1 probable transmembrane helix predicted for SEN2495 by TMHMM2.0 at aa 13-32
550537012739	intimin-like protein SinH; Provisional; Region: PRK15318
550537012740	1 probable transmembrane helix predicted for SEN2496 by TMHMM2.0 at aa 12-29
550537012741	Appears to have suffered a deletion and resulting frameshift following codon 37
550537012742	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
550537012743	HMMPfam hit to PF07191, Protein of unknown function DUF1407, score 5.2e-52
550537012744	GTP-binding protein Der; Reviewed; Region: PRK00093
550537012745	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
550537012746	G1 box; other site
550537012747	GTP/Mg2+ binding site [chemical binding]; other site
550537012748	Switch I region; other site
550537012749	G2 box; other site
550537012750	Switch II region; other site
550537012751	G3 box; other site
550537012752	G4 box; other site
550537012753	G5 box; other site
550537012754	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
550537012755	G1 box; other site
550537012756	GTP/Mg2+ binding site [chemical binding]; other site
550537012757	Switch I region; other site
550537012758	G2 box; other site
550537012759	G3 box; other site
550537012760	Switch II region; other site
550537012761	G4 box; other site
550537012762	G5 box; other site
550537012763	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 6e-45
550537012764	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012765	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 7.2e-48
550537012766	PS00017 ATP/GTP-binding site motif A (P-loop).
550537012767	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
550537012768	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
550537012769	Trp docking motif [polypeptide binding]; other site
550537012770	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 8.1e-07
550537012771	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 0.00066
550537012772	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 3.2e-05
550537012773	HMMPfam hit to PF01011, Pyrrolo-quinoline quinone, score 4.8e-08
550537012774	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012775	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
550537012776	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
550537012777	1 probable transmembrane helix predicted for SEN2501 by TMHMM2.0 at aa 21-43
550537012778	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
550537012779	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
550537012780	dimer interface [polypeptide binding]; other site
550537012781	motif 1; other site
550537012782	active site
550537012783	motif 2; other site
550537012784	motif 3; other site
550537012785	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
550537012786	anticodon binding site; other site
550537012787	HMMPfam hit to PF03129, Anticodon-binding, score 1.9e-12
550537012788	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537012789	HMMPfam hit to PF00587, Aminoacyl-tRNA synthetase, class II (G, H, P and S), score 2.9e-57
550537012790	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
550537012791	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
550537012792	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
550537012793	HMMPfam hit to PF04551, IspG protein, score 2.3e-258
550537012794	cytoskeletal protein RodZ; Provisional; Region: PRK10856
550537012795	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537012796	non-specific DNA binding site [nucleotide binding]; other site
550537012797	salt bridge; other site
550537012798	sequence-specific DNA binding site [nucleotide binding]; other site
550537012799	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
550537012800	1 probable transmembrane helix predicted for SEN2504 by TMHMM2.0 at aa 111-133
550537012801	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 2.5e-08
550537012802	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
550537012803	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537012804	FeS/SAM binding site; other site
550537012805	HMMPfam hit to PF04055, Radical SAM, score 4.3e-17
550537012806	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
550537012807	active site
550537012808	multimer interface [polypeptide binding]; other site
550537012809	HMMPfam hit to PF00334, Nucleoside diphosphate kinase, core, score 1.3e-91
550537012810	PS00469 Nucleoside diphosphate kinases active site.
550537012811	4Fe-4S binding domain; Region: Fer4; pfam00037
550537012812	hydrogenase 4 subunit H; Validated; Region: PRK08222
550537012813	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 8.1e-06
550537012814	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012815	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 1.4e-05
550537012816	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012817	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.2e-07
550537012818	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012819	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
550537012820	8 probable transmembrane helices predicted for SEN2508 by TMHMM2.0 at aa 4-26, 39-61, 84-103, 110-132, 142-164, 171-193, 221-240 and 247-266
550537012821	HMMPfam hit to PF04976, DMSO reductase anchor subunit (DmsC), score 3.8e-15
550537012822	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012823	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
550537012824	4Fe-4S binding domain; Region: Fer4; pfam00037
550537012825	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 1.1e-08
550537012826	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012827	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012828	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
550537012829	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
550537012830	putative [Fe4-S4] binding site [ion binding]; other site
550537012831	putative molybdopterin cofactor binding site [chemical binding]; other site
550537012832	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
550537012833	putative molybdopterin cofactor binding site; other site
550537012834	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 1.2e-35
550537012835	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 5.4e-75
550537012836	PS00490 Prokaryotic molybdopterin oxidoreductases signature 2.
550537012837	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 7.5e-06
550537012838	penicillin-binding protein 1C; Provisional; Region: PRK11240
550537012839	Transglycosylase; Region: Transgly; pfam00912
550537012840	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
550537012841	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
550537012842	HMMPfam hit to PF06832, Penicillin-binding, C-terminal, score 2.2e-32
550537012843	HMMPfam hit to PF00905, Penicillin-binding protein, transpeptidase, score 1.1e-10
550537012844	HMMPfam hit to PF00912, Glycosyl transferase, family 51, score 6.5e-80
550537012845	1 probable transmembrane helix predicted for SEN2511 by TMHMM2.0 at aa 9-28
550537012846	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
550537012847	MG2 domain; Region: A2M_N; pfam01835
550537012848	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
550537012849	surface patch; other site
550537012850	thioester region; other site
550537012851	specificity defining residues; other site
550537012852	HMMPfam hit to PF07703, Alpha-2-macroglobulin, N-terminal 2, score 2.4e-31
550537012853	HMMPfam hit to PF01835, Alpha-2-macroglobulin, N-terminal, score 9e-91
550537012854	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012855	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
550537012856	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
550537012857	active site residue [active]
550537012858	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
550537012859	active site residue [active]
550537012860	HMMPfam hit to PF00581, Rhodanese-like, score 2.7e-36
550537012861	PS00380 Rhodanese signature 1.
550537012862	HMMPfam hit to PF00581, Rhodanese-like, score 3.2e-27
550537012863	PS00683 Rhodanese C-terminal signature.
550537012864	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
550537012865	HMMPfam hit to PF07179, SseB, score 3.3e-200
550537012866	aminopeptidase B; Provisional; Region: PRK05015
550537012867	Peptidase; Region: DUF3663; pfam12404
550537012868	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
550537012869	interface (dimer of trimers) [polypeptide binding]; other site
550537012870	Substrate-binding/catalytic site; other site
550537012871	Zn-binding sites [ion binding]; other site
550537012872	HMMPfam hit to PF00883, Peptidase M17, leucyl aminopeptidase, C-terminal, score 1.2e-174
550537012873	PS00631 Cytosol aminopeptidase signature.
550537012874	hypothetical protein; Provisional; Region: PRK10721
550537012875	HMMPfam hit to PF04384, ISC system FeS cluster assembly, IscX, score 3.4e-47
550537012876	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
550537012877	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
550537012878	catalytic loop [active]
550537012879	iron binding site [ion binding]; other site
550537012880	HMMPfam hit to PF00111, Ferredoxin, score 9e-24
550537012881	PS00814 Adrenodoxin family, iron-sulfur binding region signature.
550537012882	chaperone protein HscA; Provisional; Region: hscA; PRK05183
550537012883	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
550537012884	nucleotide binding site [chemical binding]; other site
550537012885	putative NEF/HSP70 interaction site [polypeptide binding]; other site
550537012886	SBD interface [polypeptide binding]; other site
550537012887	HMMPfam hit to PF00012, Heat shock protein 70, score 1.1e-278
550537012888	PS01036 Heat shock hsp70 proteins family signature 3.
550537012889	PS00329 Heat shock hsp70 proteins family signature 2.
550537012890	PS00297 Heat shock hsp70 proteins family signature 1.
550537012891	co-chaperone HscB; Provisional; Region: hscB; PRK05014
550537012892	DnaJ domain; Region: DnaJ; pfam00226
550537012893	HSP70 interaction site [polypeptide binding]; other site
550537012894	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
550537012895	HMMPfam hit to PF07743, Heat shock cognate protein B, C-terminal oligomerisation, score 1.6e-29
550537012896	HMMPfam hit to PF00226, Heat shock protein DnaJ, N-terminal, score 2.8e-12
550537012897	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
550537012898	PS01152 Hypothetical hesB/yadR/yfhF family signature.
550537012899	HMMPfam hit to PF01521, HesB/YadR/YfhF, score 3.8e-44
550537012900	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
550537012901	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
550537012902	trimerization site [polypeptide binding]; other site
550537012903	active site
550537012904	HMMPfam hit to PF01592, NIF system FeS cluster assembly, NifU, N-terminal, score 2.4e-83
550537012905	cysteine desulfurase; Provisional; Region: PRK14012
550537012906	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
550537012907	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537012908	catalytic residue [active]
550537012909	HMMPfam hit to PF00266, Aminotransferase, class V, score 2.1e-125
550537012910	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
550537012911	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
550537012912	Rrf2 family protein; Region: rrf2_super; TIGR00738
550537012913	HMMPfam hit to PF02082, Transcriptional regulator, Rrf2, score 2.9e-52
550537012914	PS01332 Uncharacterized protein family UPF0074 signature.
550537012915	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
550537012916	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
550537012917	HMMPfam hit to PF00588, tRNA/rRNA methyltransferase, SpoU, score 1.1e-36
550537012918	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
550537012919	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
550537012920	active site
550537012921	dimerization interface [polypeptide binding]; other site
550537012922	HMMPfam hit to PF00459, Inositol monophosphatase, score 7.2e-117
550537012923	PS00629 Inositol monophosphatase family signature 1.
550537012924	PS00630 Inositol monophosphatase family signature 2.
550537012925	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
550537012926	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
550537012927	1 probable transmembrane helix predicted for SEN2527 by TMHMM2.0 at aa 13-35
550537012928	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 2.5e-06
550537012929	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
550537012930	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
550537012931	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012932	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0073
550537012933	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012934	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
550537012935	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
550537012936	FAD binding pocket [chemical binding]; other site
550537012937	FAD binding motif [chemical binding]; other site
550537012938	phosphate binding motif [ion binding]; other site
550537012939	beta-alpha-beta structure motif; other site
550537012940	NAD binding pocket [chemical binding]; other site
550537012941	Iron coordination center [ion binding]; other site
550537012942	HMMPfam hit to PF00970, Oxidoreductase FAD-binding region, score 9.6e-08
550537012943	HMMPfam hit to PF00175, Oxidoreductase FAD/NAD(P)-binding, score 3.6e-27
550537012944	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
550537012945	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
550537012946	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
550537012947	HMMPfam hit to PF03460, Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like, score 2.2e-09
550537012948	HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S region, score 1.7e-28
550537012949	PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site.
550537012950	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 4.2e-05
550537012951	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.3e-06
550537012952	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537012953	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
550537012954	HMMPfam hit to PF03824, Nickel/cobalt transporter, high-affinity, score 1.7e-91
550537012955	7 probable transmembrane helices predicted for SEN2531 by TMHMM2.0 at aa 13-35, 75-97, 110-132, 147-169, 225-247, 251-273 and 294-316
550537012956	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
550537012957	HMMPfam hit to PF06226, Protein of unknown function DUF1007, score 3.2e-126
550537012958	1 probable transmembrane helix predicted for SEN2532 by TMHMM2.0 at aa 7-24
550537012959	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
550537012960	PRD domain; Region: PRD; pfam00874
550537012961	PRD domain; Region: PRD; pfam00874
550537012962	HMMPfam hit to PF00874, PRD, score 2.3e-15
550537012963	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537012964	HMMPfam hit to PF00874, PRD, score 3e-14
550537012965	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
550537012966	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537012967	putative substrate translocation pore; other site
550537012968	12 probable transmembrane helices predicted for SEN2534 by TMHMM2.0 at aa 9-31, 41-63, 70-89, 93-111, 132-154, 158-180, 207-229, 234-256, 269-288, 293-315, 328-350 and 354-371
550537012969	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 9.1e-18
550537012970	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
550537012971	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
550537012972	dimer interface [polypeptide binding]; other site
550537012973	active site
550537012974	glycine-pyridoxal phosphate binding site [chemical binding]; other site
550537012975	folate binding site [chemical binding]; other site
550537012976	HMMPfam hit to PF00464, Glycine hydroxymethyltransferase, score 1.9e-287
550537012977	PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site.
550537012978	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
550537012979	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
550537012980	heme-binding site [chemical binding]; other site
550537012981	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
550537012982	FAD binding pocket [chemical binding]; other site
550537012983	FAD binding motif [chemical binding]; other site
550537012984	phosphate binding motif [ion binding]; other site
550537012985	beta-alpha-beta structure motif; other site
550537012986	NAD binding pocket [chemical binding]; other site
550537012987	Heme binding  pocket [chemical binding]; other site
550537012988	HMMPfam hit to PF00042, Globin, subset, score 1.3e-27
550537012989	HMMPfam hit to PF00970, Oxidoreductase FAD-binding region, score 4e-12
550537012990	HMMPfam hit to PF00175, Oxidoreductase FAD/NAD(P)-binding, score 1.3e-19
550537012991	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
550537012992	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537012993	DNA binding site [nucleotide binding]
550537012994	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 4.7e-19
550537012995	1 probable transmembrane helix predicted for SEN2537 by TMHMM2.0 at aa 162-184
550537012996	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
550537012997	12 probable transmembrane helices predicted for SEN2538 by TMHMM2.0 at aa 7-29, 39-58, 93-115, 120-142, 149-171, 186-208, 220-242, 265-287, 322-344, 354-371, 384-403 and 407-424
550537012998	HMMPfam hit to PF00324, Amino acid permease-associated region, score 4.3e-05
550537012999	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013000	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013001	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013002	lysine decarboxylase CadA; Provisional; Region: PRK15400
550537013003	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
550537013004	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
550537013005	homodimer interface [polypeptide binding]; other site
550537013006	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537013007	catalytic residue [active]
550537013008	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
550537013009	HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal, score 2.2e-44
550537013010	HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major region, score 9e-297
550537013011	PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site.
550537013012	HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal, score 2.6e-85
550537013013	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
550537013014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537013015	putative substrate translocation pore; other site
550537013016	POT family; Region: PTR2; pfam00854
550537013017	14 probable transmembrane helices predicted for SEN2540 by TMHMM2.0 at aa 9-31, 46-68, 71-93, 103-125, 138-160, 164-186, 207-229, 234-251, 264-281, 307-329, 341-363, 373-395, 407-429 and 449-471
550537013018	PS01022 PTR2 family proton/oligopeptide symporters signature 1.
550537013019	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537013020	HMMPfam hit to PF00854, TGF-beta receptor, type I/II extracellular region, score 1.9e-87
550537013021	PS01023 PTR2 family proton/oligopeptide symporters signature 2.
550537013022	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
550537013023	Nitrogen regulatory protein P-II; Region: P-II; smart00938
550537013024	HMMPfam hit to PF00543, Nitrogen regulatory protein PII, score 7.2e-79
550537013025	PS00638 P-II protein C-terminal region signature.
550537013026	PS00496 P-II protein urydylation site.
550537013027	response regulator GlrR; Provisional; Region: PRK15115
550537013028	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537013029	active site
550537013030	phosphorylation site [posttranslational modification]
550537013031	intermolecular recognition site; other site
550537013032	dimerization interface [polypeptide binding]; other site
550537013033	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537013034	Walker A motif; other site
550537013035	ATP binding site [chemical binding]; other site
550537013036	Walker B motif; other site
550537013037	arginine finger; other site
550537013038	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537013039	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 2.2e-150
550537013040	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537013041	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537013042	HMMPfam hit to PF00072, Response regulator receiver, score 3.7e-46
550537013043	hypothetical protein; Provisional; Region: PRK10722
550537013044	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013045	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
550537013046	HAMP domain; Region: HAMP; pfam00672
550537013047	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537013048	dimer interface [polypeptide binding]; other site
550537013049	phosphorylation site [posttranslational modification]
550537013050	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537013051	ATP binding site [chemical binding]; other site
550537013052	Mg2+ binding site [ion binding]; other site
550537013053	G-X-G motif; other site
550537013054	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 4e-28
550537013055	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 2.3e-18
550537013056	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1e-08
550537013057	2 probable transmembrane helices predicted for SEN2544 by TMHMM2.0 at aa 15-37 and 179-201
550537013058	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
550537013059	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
550537013060	dimerization interface [polypeptide binding]; other site
550537013061	ATP binding site [chemical binding]; other site
550537013062	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
550537013063	dimerization interface [polypeptide binding]; other site
550537013064	ATP binding site [chemical binding]; other site
550537013065	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
550537013066	putative active site [active]
550537013067	catalytic triad [active]
550537013068	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013069	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal, score 3.4e-26
550537013070	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal, score 5.9e-34
550537013071	HMMPfam hit to PF00586, AIR synthase related protein, score 2.3e-49
550537013072	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
550537013073	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537013074	substrate binding pocket [chemical binding]; other site
550537013075	membrane-bound complex binding site; other site
550537013076	hinge residues; other site
550537013077	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
550537013078	N-acetyl-D-glucosamine binding site [chemical binding]; other site
550537013079	catalytic residue [active]
550537013080	1 probable transmembrane helix predicted for SEN2547 by TMHMM2.0 at aa 7-29
550537013081	HMMPfam hit to PF01464, Lytic transglycosylase-like, catalytic, score 3e-38
550537013082	PS00922 Prokaryotic transglycosylases signature.
550537013083	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
550537013084	nucleoside/Zn binding site; other site
550537013085	dimer interface [polypeptide binding]; other site
550537013086	catalytic motif [active]
550537013087	HMMPfam hit to PF00383, CMP/dCMP deaminase, zinc-binding, score 5.2e-46
550537013088	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
550537013089	hypothetical protein; Provisional; Region: PRK11590
550537013090	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
550537013091	1 probable transmembrane helix predicted for SEN2549 by TMHMM2.0 at aa 35-54
550537013092	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
550537013093	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
550537013094	active site turn [active]
550537013095	phosphorylation site [posttranslational modification]
550537013096	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
550537013097	9 probable transmembrane helices predicted for SEN2550 by TMHMM2.0 at aa 117-139, 154-176, 214-231, 246-268, 288-310, 325-346, 359-381, 396-418 and 425-447
550537013098	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 6.7e-36
550537013099	HMMPfam hit to PF00367, Phosphotransferase system, EIIB, score 2.1e-10
550537013100	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
550537013101	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
550537013102	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
550537013103	putative active site [active]
550537013104	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 4.8e-08
550537013105	PS01272 Glucokinase regulatory protein family signature.
550537013106	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013107	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
550537013108	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
550537013109	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
550537013110	putative active site [active]
550537013111	HMMPfam hit to PF01418, Helix-turn-helix protein RpiR, score 4.3e-52
550537013112	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 2.8e-33
550537013113	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
550537013114	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
550537013115	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
550537013116	HMMPfam hit to PF08546, Ketopantoate reductase ApbA/PanE, C-terminal, score 1.9e-54
550537013117	HMMPfam hit to PF02558, Ketopantoate reductase ApbA/PanE, N-terminal, score 2e-34
550537013118	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
550537013119	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537013120	putative substrate translocation pore; other site
550537013121	12 probable transmembrane helices predicted for SEN2554 by TMHMM2.0 at aa 10-29, 42-64, 74-93, 98-115, 130-152, 165-184, 213-235, 242-264, 274-296, 301-323, 338-357 and 364-386
550537013122	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4e-48
550537013123	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537013124	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537013125	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
550537013126	dimerization interface [polypeptide binding]; other site
550537013127	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.5e-16
550537013128	PS00044 Bacterial regulatory proteins, lysR family signature.
550537013129	HMMPfam hit to PF03466, LysR, substrate-binding, score 5.3e-30
550537013130	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
550537013131	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2e-05
550537013132	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537013133	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
550537013134	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase, score 2.5e-22
550537013135	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
550537013136	active site
550537013137	hydrophilic channel; other site
550537013138	dimerization interface [polypeptide binding]; other site
550537013139	catalytic residues [active]
550537013140	active site lid [active]
550537013141	HMMPfam hit to PF03740, Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ, score 2.6e-148
550537013142	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
550537013143	Recombination protein O N terminal; Region: RecO_N; pfam11967
550537013144	Recombination protein O C terminal; Region: RecO_C; pfam02565
550537013145	HMMPfam hit to PF02565, Recombination protein O, RecO, score 3.4e-117
550537013146	GTPase Era; Reviewed; Region: era; PRK00089
550537013147	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
550537013148	G1 box; other site
550537013149	GTP/Mg2+ binding site [chemical binding]; other site
550537013150	Switch I region; other site
550537013151	G2 box; other site
550537013152	Switch II region; other site
550537013153	G3 box; other site
550537013154	G4 box; other site
550537013155	G5 box; other site
550537013156	KH domain; Region: KH_2; pfam07650
550537013157	HMMPfam hit to PF07650, K Homology, type 2, score 1e-25
550537013158	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 2.5e-39
550537013159	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013160	ribonuclease III; Reviewed; Region: rnc; PRK00102
550537013161	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
550537013162	dimerization interface [polypeptide binding]; other site
550537013163	active site
550537013164	metal binding site [ion binding]; metal-binding site
550537013165	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
550537013166	dsRNA binding site [nucleotide binding]; other site
550537013167	HMMPfam hit to PF00035, Double-stranded RNA binding, score 2.7e-17
550537013168	HMMPfam hit to PF00636, Ribonuclease III, score 2.2e-45
550537013169	PS00517 Ribonuclease III family signature.
550537013170	signal peptidase I; Provisional; Region: PRK10861
550537013171	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
550537013172	Catalytic site [active]
550537013173	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
550537013174	PS00761 Signal peptidases I signature 3.
550537013175	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013176	HMMPfam hit to PF00717, Peptidase S24, S26A and S26B, C-terminal, score 2.1e-24
550537013177	PS00760 Signal peptidases I lysine active site.
550537013178	PS00501 Signal peptidases I serine active site.
550537013179	2 probable transmembrane helices predicted for SEN2562 by TMHMM2.0 at aa 5-27 and 60-82
550537013180	GTP-binding protein LepA; Provisional; Region: PRK05433
550537013181	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
550537013182	G1 box; other site
550537013183	putative GEF interaction site [polypeptide binding]; other site
550537013184	GTP/Mg2+ binding site [chemical binding]; other site
550537013185	Switch I region; other site
550537013186	G2 box; other site
550537013187	G3 box; other site
550537013188	Switch II region; other site
550537013189	G4 box; other site
550537013190	G5 box; other site
550537013191	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
550537013192	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
550537013193	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
550537013194	HMMPfam hit to PF06421, GTP-binding protein LepA, C-terminal, score 8.7e-80
550537013195	HMMPfam hit to PF00679, Translation elongation factor EFG/EF2, C-terminal, score 3.3e-32
550537013196	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 1.3e-11
550537013197	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 1.7e-73
550537013198	PS00301 GTP-binding elongation factors signature.
550537013199	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013200	SoxR reducing system protein RseC; Provisional; Region: PRK10862
550537013201	HMMPfam hit to PF04246, Positive regulator of sigma(E), RseC/MucC, score 1.6e-70
550537013202	2 probable transmembrane helices predicted for SEN2564 by TMHMM2.0 at aa 78-100 and 104-121
550537013203	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013204	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
550537013205	anti-sigma E factor; Provisional; Region: rseB; PRK09455
550537013206	HMMPfam hit to PF03888, MucB/RseB, score 7.4e-203
550537013207	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
550537013208	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
550537013209	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
550537013210	HMMPfam hit to PF03873, Anti sigma-E protein RseA, C-terminal, score 7.9e-25
550537013211	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013212	HMMPfam hit to PF03872, Anti sigma-E protein RseA, N-terminal, score 2.1e-56
550537013213	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
550537013214	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
550537013215	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
550537013216	DNA binding residues [nucleotide binding]
550537013217	HMMPfam hit to PF08281, RNA polymerase sigma factor 70, region 4 type 2, score 1.5e-21
550537013218	HMMPfam hit to PF04542, RNA polymerase sigma-70 region 2, score 8.6e-21
550537013219	PS01063 Sigma-70 factors ECF subfamily signature.
550537013220	L-aspartate oxidase; Provisional; Region: PRK09077
550537013221	L-aspartate oxidase; Provisional; Region: PRK06175
550537013222	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
550537013223	HMMPfam hit to PF00890, Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal, score 7.1e-140
550537013224	HMMPfam hit to PF02910, Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal, score 9.9e-07
550537013225	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
550537013226	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537013227	S-adenosylmethionine binding site [chemical binding]; other site
550537013228	HMMPfam hit to PF05175, Methyltransferase small, score 7e-06
550537013229	PS00092 N-6 Adenine-specific DNA methylases signature.
550537013230	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
550537013231	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
550537013232	ATP binding site [chemical binding]; other site
550537013233	Mg++ binding site [ion binding]; other site
550537013234	motif III; other site
550537013235	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537013236	nucleotide binding region [chemical binding]; other site
550537013237	ATP-binding site [chemical binding]; other site
550537013238	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 3.6e-71
550537013239	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013240	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
550537013241	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 2.4e-31
550537013242	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537013243	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537013244	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
550537013245	dimerization interface [polypeptide binding]; other site
550537013246	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.4e-43
550537013247	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 7.1e-14
550537013248	PS00044 Bacterial regulatory proteins, lysR family signature.
550537013249	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
550537013250	6 probable transmembrane helices predicted for SEN2572 by TMHMM2.0 at aa 10-32, 44-66, 70-92, 105-127, 142-164 and 177-194
550537013251	HMMPfam hit to PF01810, Lysine exporter protein (LYSE/YGGA), score 0.00046
550537013252	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
550537013253	HMMPfam hit to PF01228, Formate C-acetyltransferase glycine radical, score 2.9e-51
550537013254	PS00850 Glycine radical signature.
550537013255	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
550537013256	ligand binding site [chemical binding]; other site
550537013257	active site
550537013258	UGI interface [polypeptide binding]; other site
550537013259	catalytic site [active]
550537013260	HMMPfam hit to PF03167, Uracil-DNA glycosylase superfamily, score 1.9e-85
550537013261	PS00130 Uracil-DNA glycosylase signature.
550537013262	putative methyltransferase; Provisional; Region: PRK10864
550537013263	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
550537013264	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
550537013265	HMMPfam hit to PF00588, tRNA/rRNA methyltransferase, SpoU, score 2e-39
550537013266	HMMPfam hit to PF08032, RNA 2-O ribose methyltransferase, substrate binding, score 5.2e-14
550537013267	thioredoxin 2; Provisional; Region: PRK10996
550537013268	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
550537013269	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
550537013270	catalytic residues [active]
550537013271	HMMPfam hit to PF00085, Thioredoxin domain, score 3.5e-35
550537013272	Uncharacterized conserved protein [Function unknown]; Region: COG3148
550537013273	HMMPfam hit to PF03942, DTW, score 2.2e-83
550537013274	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
550537013275	CoA binding domain; Region: CoA_binding_2; pfam13380
550537013276	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
550537013277	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
550537013278	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
550537013279	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537013280	Coenzyme A binding pocket [chemical binding]; other site
550537013281	HMMPfam hit to PF02629, CoA-binding, score 0.00028
550537013282	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 1.1e-14
550537013283	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
550537013284	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
550537013285	domain interface [polypeptide binding]; other site
550537013286	putative active site [active]
550537013287	catalytic site [active]
550537013288	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
550537013289	domain interface [polypeptide binding]; other site
550537013290	putative active site [active]
550537013291	catalytic site [active]
550537013292	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 1.6e-05
550537013293	HMMPfam hit to PF00614, Phospholipase D/Transphosphatidylase, score 1.2e-07
550537013294	lipoprotein; Provisional; Region: PRK10759
550537013295	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013296	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
550537013297	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537013298	putative substrate translocation pore; other site
550537013299	HMMPfam hit to PF00083, General substrate transporter, score 7.4e-27
550537013300	12 probable transmembrane helices predicted for SEN2581 by TMHMM2.0 at aa 21-43, 63-85, 97-114, 119-141, 161-183, 198-215, 245-267, 282-304, 311-328, 338-360, 373-395 and 405-424
550537013301	PS00217 Sugar transport proteins signature 2.
550537013302	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013303	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
550537013304	protein disaggregation chaperone; Provisional; Region: PRK10865
550537013305	Clp amino terminal domain; Region: Clp_N; pfam02861
550537013306	Clp amino terminal domain; Region: Clp_N; pfam02861
550537013307	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537013308	Walker A motif; other site
550537013309	ATP binding site [chemical binding]; other site
550537013310	Walker B motif; other site
550537013311	arginine finger; other site
550537013312	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537013313	Walker A motif; other site
550537013314	ATP binding site [chemical binding]; other site
550537013315	Walker B motif; other site
550537013316	arginine finger; other site
550537013317	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
550537013318	HMMPfam hit to PF07724, ATPase AAA-2, score 6.1e-112
550537013319	PS00871 Chaperonins clpA/B signature 2.
550537013320	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013321	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013322	PS00870 Chaperonins clpA/B signature 1.
550537013323	HMMPfam hit to PF00004, AAA ATPase, core, score 4.2e-12
550537013324	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013325	HMMPfam hit to PF02861, Clp, N-terminal, score 1.2e-13
550537013326	HMMPfam hit to PF02861, Clp, N-terminal, score 3.2e-17
550537013327	hypothetical protein; Provisional; Region: PRK10723
550537013328	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
550537013329	HMMPfam hit to PF02578, Protein of unknown function DUF152, score 7.4e-113
550537013330	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
550537013331	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537013332	RNA binding surface [nucleotide binding]; other site
550537013333	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
550537013334	active site
550537013335	HMMPfam hit to PF00849, Pseudouridine synthase, score 2.4e-67
550537013336	PS01129 Rlu family of pseudouridine synthase signature.
550537013337	HMMPfam hit to PF01479, RNA-binding S4, score 3.7e-13
550537013338	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
550537013339	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
550537013340	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013341	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
550537013342	30S subunit binding site; other site
550537013343	HMMPfam hit to PF02482, Ribosomal protein S30Ae/sigma 54 modulation protein, score 7.8e-49
550537013344	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
550537013345	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
550537013346	Prephenate dehydratase; Region: PDT; pfam00800
550537013347	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
550537013348	putative L-Phe binding site [chemical binding]; other site
550537013349	HMMPfam hit to PF01817, Chorismate mutase, score 1.8e-29
550537013350	HMMPfam hit to PF00800, Prephenate dehydratase, score 5.3e-89
550537013351	PS00858 Prephenate dehydratase signature 2.
550537013352	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
550537013353	HMMPfam hit to PF08450, SMP-30/Gluconolaconase/LRE-like region, score 2.7e-115
550537013354	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
550537013355	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
550537013356	prephenate dehydrogenase; Validated; Region: PRK08507
550537013357	HMMPfam hit to PF02153, Prephenate dehydrogenase, score 5.8e-18
550537013358	HMMPfam hit to PF01817, Chorismate mutase, score 9.1e-18
550537013359	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
550537013360	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
550537013361	HMMPfam hit to PF00793, DAHP synthetase I/KDSA, score 1.4e-173
550537013362	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
550537013363	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
550537013364	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537013365	metal binding site [ion binding]; metal-binding site
550537013366	active site
550537013367	I-site; other site
550537013368	2 probable transmembrane helices predicted for SEN2593 by TMHMM2.0 at aa 21-43 and 153-175
550537013369	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013370	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 8e-07
550537013371	HMMPfam hit to PF00990, GGDEF, score 1.5e-50
550537013372	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
550537013373	HMMPfam hit to PF01245, Ribosomal protein L19, score 1.3e-82
550537013374	PS01015 Ribosomal protein L19 signature.
550537013375	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
550537013376	HMMPfam hit to PF01746, tRNA (guanine-N1-)-methyltransferase, score 3.4e-93
550537013377	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
550537013378	RimM N-terminal domain; Region: RimM; pfam01782
550537013379	PRC-barrel domain; Region: PRC; pfam05239
550537013380	HMMPfam hit to PF05239, PRC-barrel, score 1.7e-13
550537013381	HMMPfam hit to PF01782, RimM protein, score 1.9e-37
550537013382	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
550537013383	HMMPfam hit to PF00886, Ribosomal protein S16, score 2.9e-35
550537013384	PS00732 Ribosomal protein S16 signature.
550537013385	signal recognition particle protein; Provisional; Region: PRK10867
550537013386	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
550537013387	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
550537013388	P loop; other site
550537013389	GTP binding site [chemical binding]; other site
550537013390	Signal peptide binding domain; Region: SRP_SPB; pfam02978
550537013391	HMMPfam hit to PF02978, Signal recognition particle, SRP54 subunit, M-domain, score 1.3e-52
550537013392	HMMPfam hit to PF00448, Signal recognition particle, SRP54 subunit, GTPase, score 2.8e-119
550537013393	PS00300 SRP54-type proteins GTP-binding domain signature.
550537013394	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537013395	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013396	HMMPfam hit to PF02881, Signal recognition particle, SRP54 subunit, helical bundle, score 1.9e-35
550537013397	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
550537013398	8 probable transmembrane helices predicted for SEN2599 by TMHMM2.0 at aa 2-24, 34-56, 63-85, 90-109, 129-151, 176-198, 210-227 and 237-254
550537013399	HMMPfam hit to PF01578, Cytochrome c assembly protein, score 4.6e-73
550537013400	hypothetical protein; Provisional; Region: PRK11573
550537013401	Domain of unknown function DUF21; Region: DUF21; pfam01595
550537013402	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
550537013403	Transporter associated domain; Region: CorC_HlyC; smart01091
550537013404	HMMPfam hit to PF01595, Protein of unknown function DUF21, score 1.5e-61
550537013405	3 probable transmembrane helices predicted for SEN2600 by TMHMM2.0 at aa 33-55, 65-83 and 95-117
550537013406	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 6.8e-16
550537013407	HMMPfam hit to PF03471, Transporter-associated region, score 2.4e-24
550537013408	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
550537013409	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
550537013410	dimer interface [polypeptide binding]; other site
550537013411	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
550537013412	HMMPfam hit to PF01025, GrpE nucleotide exchange factor, score 6.9e-74
550537013413	PS01071 grpE protein signature.
550537013414	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
550537013415	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
550537013416	HMMPfam hit to PF01513, ATP-NAD/AcoX kinase, score 1.1e-102
550537013417	recombination and repair protein; Provisional; Region: PRK10869
550537013418	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
550537013419	Walker A/P-loop; other site
550537013420	ATP binding site [chemical binding]; other site
550537013421	Q-loop/lid; other site
550537013422	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
550537013423	ABC transporter signature motif; other site
550537013424	Walker B; other site
550537013425	D-loop; other site
550537013426	H-loop/switch region; other site
550537013427	HMMPfam hit to PF02463, SMC protein, N-terminal, score 1.8e-10
550537013428	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013429	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
550537013430	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
550537013431	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013432	HMMPfam hit to PF04355, SmpA/OmlA, score 2e-41
550537013433	PS00018 EF-hand calcium-binding domain.
550537013434	PS00215 Mitochondrial energy transfer proteins signature.
550537013435	hypothetical protein; Validated; Region: PRK01777
550537013436	HMMPfam hit to PF03658, Protein of unknown function UPF0125, score 1e-52
550537013437	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
550537013438	putative coenzyme Q binding site [chemical binding]; other site
550537013439	PS00036 bZIP transcription factors basic domain signature.
550537013440	HMMPfam hit to PF03364, Streptomyces cyclase/dehydrase, score 3.5e-44
550537013441	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
550537013442	SmpB-tmRNA interface; other site
550537013443	HMMPfam hit to PF01668, SmpB protein, score 2.5e-41
550537013444	PS01317 Protein smpB signature.
550537013445	Salmonella pathogenicity island 9: SPI-9
550537013446	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013447	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013448	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013449	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013450	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013451	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013452	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013453	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013454	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013455	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013456	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013457	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537013458	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013459	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013460	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537013461	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013462	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537013463	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
550537013464	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
550537013465	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.8e-26
550537013466	HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.3e-15
550537013467	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
550537013468	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537013469	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537013470	Walker A/P-loop; other site
550537013471	ATP binding site [chemical binding]; other site
550537013472	Q-loop/lid; other site
550537013473	ABC transporter signature motif; other site
550537013474	Walker B; other site
550537013475	D-loop; other site
550537013476	H-loop/switch region; other site
550537013477	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013478	HMMPfam hit to PF00664, ABC transporter, transmembrane region, score 6.8e-17
550537013479	5 probable transmembrane helices predicted for SEN2611 by TMHMM2.0 at aa 168-190, 205-222, 281-303, 307-324 and 389-411
550537013480	HMMPfam hit to PF00005, ABC transporter related, score 8.9e-51
550537013481	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013482	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
550537013483	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537013484	1 probable transmembrane helix predicted for SEN2612 by TMHMM2.0 at aa 13-35
550537013485	HMMPfam hit to PF00529, Secretion protein HlyD, score 1.6e-08
550537013486	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537013487	PS00543 HlyD family secretion proteins signature.
550537013488	2 probable transmembrane helices predicted for SEN2613 by TMHMM2.0 at aa 19-41 and 61-83
550537013489	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
550537013490	This CDS has been interrupted by the insertion of an IS element
550537013491	HMMPfam hit to PF01797, Transposase IS200-like, score 2.4e-70
550537013492	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
550537013493	DNA-binding interface [nucleotide binding]; DNA binding site
550537013494	IS2 transposase TnpB; Reviewed; Region: PRK09409
550537013495	HTH-like domain; Region: HTH_21; pfam13276
550537013496	Integrase core domain; Region: rve; pfam00665
550537013497	Integrase core domain; Region: rve_3; pfam13683
550537013498	HMMPfam hit to PF00665, Integrase, catalytic core, score 2.9e-34
550537013499	HMMPfam hit to PF01527, Transposase IS3/IS911, score 1.5e-28
550537013500	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
550537013501	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
550537013502	homodimer interface [polypeptide binding]; other site
550537013503	active site
550537013504	TDP-binding site; other site
550537013505	acceptor substrate-binding pocket; other site
550537013506	HMMPfam hit to PF06722, Protein of unknown function DUF1205, score 9e-44
550537013507	PS00215 Mitochondrial energy transfer proteins signature.
550537013508	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537013509	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537013510	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
550537013511	Walker A/P-loop; other site
550537013512	ATP binding site [chemical binding]; other site
550537013513	Q-loop/lid; other site
550537013514	ABC transporter signature motif; other site
550537013515	Walker B; other site
550537013516	D-loop; other site
550537013517	H-loop/switch region; other site
550537013518	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
550537013519	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
550537013520	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537013521	Walker A/P-loop; other site
550537013522	ATP binding site [chemical binding]; other site
550537013523	Q-loop/lid; other site
550537013524	ABC transporter signature motif; other site
550537013525	Walker B; other site
550537013526	D-loop; other site
550537013527	H-loop/switch region; other site
550537013528	11 probable transmembrane helices predicted for SEN2620 by TMHMM2.0 at aa 27-49, 64-83, 138-160, 165-182, 243-265, 280-302, 649-671, 686-708, 767-786, 790-809 and 871-893
550537013529	HMMPfam hit to PF00664, ABC transporter, transmembrane region, score 6.4e-21
550537013530	HMMPfam hit to PF00005, ABC transporter related, score 4.2e-61
550537013531	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013532	PS00211 ABC transporters family signature.
550537013533	HMMPfam hit to PF00664, ABC transporter, transmembrane region, score 2e-32
550537013534	HMMPfam hit to PF00005, ABC transporter related, score 2.1e-51
550537013535	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013536	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
550537013537	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
550537013538	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
550537013539	HMMPfam hit to PF00756,  esterase, score 1.3e-74
550537013540	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
550537013541	1 probable transmembrane helix predicted for SEN2622 by TMHMM2.0 at aa 13-30
550537013542	outer membrane receptor FepA; Provisional; Region: PRK13528
550537013543	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537013544	N-terminal plug; other site
550537013545	ligand-binding site [chemical binding]; other site
550537013546	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 1.3e-32
550537013547	PS01156 TonB-dependent receptor proteins signature 2.
550537013548	PS00449 ATP synthase a subunit signature.
550537013549	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 9.5e-32
550537013550	secreted effector protein PipB2; Provisional; Region: PRK15196
550537013551	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537013552	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537013553	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537013554	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537013555	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
550537013556	HMMPfam hit to PF00805, Pentapeptide repeat, score 1.6e-08
550537013557	HMMPfam hit to PF00805, Pentapeptide repeat, score 5.3e-09
550537013558	HMMPfam hit to PF00805, Pentapeptide repeat, score 6e-08
550537013559	HMMPfam hit to PF00805, Pentapeptide repeat, score 3.5e-06
550537013560	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
550537013561	HMMPfam hit to PF04393, Protein of unknown function DUF535, score 6.7e-154
550537013562	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
550537013563	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
550537013564	HMMPfam hit to PF07395, Mig-14, score 1.1e-194
550537013565	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
550537013566	7 probable transmembrane helices predicted for SEN2627 by TMHMM2.0 at aa 10-32, 76-98, 118-140, 176-198, 213-235, 256-278 and 306-325
550537013567	HMMPfam hit to PF03824, Nickel/cobalt transporter, high-affinity, score 1.5e-128
550537013568	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013569	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
550537013570	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
550537013571	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
550537013572	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537013573	dimer interface [polypeptide binding]; other site
550537013574	phosphorylation site [posttranslational modification]
550537013575	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537013576	ATP binding site [chemical binding]; other site
550537013577	Mg2+ binding site [ion binding]; other site
550537013578	G-X-G motif; other site
550537013579	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.4e-28
550537013580	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 2.2e-08
550537013581	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 9.6e-11
550537013582	2 probable transmembrane helices predicted for SEN2628 by TMHMM2.0 at aa 15-37 and 170-192
550537013583	HMMPfam hit to PF08521, Two-component sensor kinase N-terminal, score 5.6e-77
550537013584	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537013585	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
550537013586	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537013587	active site
550537013588	phosphorylation site [posttranslational modification]
550537013589	intermolecular recognition site; other site
550537013590	dimerization interface [polypeptide binding]; other site
550537013591	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537013592	DNA binding site [nucleotide binding]
550537013593	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 4.6e-18
550537013594	HMMPfam hit to PF00072, Response regulator receiver, score 5.7e-35
550537013595	PS00217 Sugar transport proteins signature 2.
550537013596	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
550537013597	HMMPfam hit to PF03401, Bordetella uptake gene, score 2.9e-08
550537013598	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
550537013599	4 probable transmembrane helices predicted for SEN2631 by TMHMM2.0 at aa 7-24, 39-56, 69-91 and 106-128
550537013600	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
550537013601	HMMPfam hit to PF01970, Protein of unknown function DUF112, transmembrane, score 3.4e-224
550537013602	12 probable transmembrane helices predicted for SEN2632 by TMHMM2.0 at aa 20-42, 47-69, 110-132, 142-164, 171-193, 208-230, 260-282, 321-343, 356-378, 388-410, 415-433 and 470-492
550537013603	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013604	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
550537013605	substrate binding pocket [chemical binding]; other site
550537013606	active site
550537013607	iron coordination sites [ion binding]; other site
550537013608	HMMPfam hit to PF08943, Protein of unknown function CsiD, score 2.5e-237
550537013609	Predicted dehydrogenase [General function prediction only]; Region: COG0579
550537013610	hydroxyglutarate oxidase; Provisional; Region: PRK11728
550537013611	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.5e-76
550537013612	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
550537013613	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
550537013614	tetramerization interface [polypeptide binding]; other site
550537013615	NAD(P) binding site [chemical binding]; other site
550537013616	catalytic residues [active]
550537013617	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 5.5e-246
550537013618	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537013619	PS00070 Aldehyde dehydrogenases cysteine active site.
550537013620	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
550537013621	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
550537013622	inhibitor-cofactor binding pocket; inhibition site
550537013623	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537013624	catalytic residue [active]
550537013625	HMMPfam hit to PF00202, Aminotransferase class-III, score 6.6e-174
550537013626	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
550537013627	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
550537013628	HMMPfam hit to PF00324, Amino acid permease-associated region, score 1.4e-169
550537013629	12 probable transmembrane helices predicted for SEN2637 by TMHMM2.0 at aa 19-41, 46-65, 86-108, 123-145, 152-174, 202-224, 245-267, 287-309, 335-357, 362-381, 401-423 and 427-449
550537013630	PS00218 Amino acid permeases signature.
550537013631	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013632	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
550537013633	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537013634	DNA-binding site [nucleotide binding]; DNA binding site
550537013635	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
550537013636	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 4.6e-14
550537013637	PS00043 Bacterial regulatory proteins, gntR family signature.
550537013638	HMMPfam hit to PF07729, GntR, C-terminal, score 5.7e-10
550537013639	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013640	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
550537013641	bacterial OsmY and nodulation domain; Region: BON; smart00749
550537013642	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537013643	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 2.8e-13
550537013644	HMMPfam hit to PF04972, Transport-associated, score 2.3e-10
550537013645	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
550537013646	HMMPfam hit to PF01679, Protein of unknown function UPF0057, score 9.1e-24
550537013647	2 probable transmembrane helices predicted for SEN2640 by TMHMM2.0 at aa 2-20 and 25-47
550537013648	PS01309 Uncharacterized protein family UPF0057 signature.
550537013649	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537013650	dimerization interface [polypeptide binding]; other site
550537013651	putative DNA binding site [nucleotide binding]; other site
550537013652	Transcriptional regulators [Transcription]; Region: MarR; COG1846
550537013653	putative Zn2+ binding site [ion binding]; other site
550537013654	HMMPfam hit to PF01022, Bacterial regulatory protein, ArsR, score 7.6e-18
550537013655	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
550537013656	active site residue [active]
550537013657	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
550537013658	HMMPfam hit to PF00581, Rhodanese-like, score 2.5e-10
550537013659	2 probable transmembrane helices predicted for SEN2642 by TMHMM2.0 at aa 117-139 and 143-165
550537013660	PS00287 Cysteine proteases inhibitors signature.
550537013661	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
550537013662	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
550537013663	HMMPfam hit to PF00816, Histone-like nucleoid-structuring protein H-NS, score 8e-50
550537013664	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
550537013665	HMMPfam hit to PF06610, Protein of unknown function DUF1144, score 2.2e-98
550537013666	4 probable transmembrane helices predicted for SEN2644 by TMHMM2.0 at aa 12-34, 44-62, 83-105 and 110-132
550537013667	hypothetical protein; Provisional; Region: PRK10556
550537013668	hypothetical protein; Provisional; Region: PRK10132
550537013669	HMMPfam hit to PF05957, Protein of unknown function DUF883, ElaB, score 5.3e-48
550537013670	1 probable transmembrane helix predicted for SEN2646 by TMHMM2.0 at aa 91-110
550537013671	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
550537013672	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537013673	DNA-binding site [nucleotide binding]; DNA binding site
550537013674	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537013675	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537013676	homodimer interface [polypeptide binding]; other site
550537013677	catalytic residue [active]
550537013678	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 1.3e-06
550537013679	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 4.5e-23
550537013680	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
550537013681	Uncharacterized conserved protein [Function unknown]; Region: COG2128
550537013682	HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase, score 1.6e-22
550537013683	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
550537013684	catalytic residues [active]
550537013685	HMMPfam hit to PF00462, Glutaredoxin, score 5.3e-15
550537013686	PS00190 Cytochrome c family heme-binding site signature.
550537013687	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
550537013688	HMMPfam hit to PF07972, Ribonucleotide reductase Class Ib, NrdI, score 1.9e-75
550537013689	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
550537013690	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
550537013691	Class I ribonucleotide reductase; Region: RNR_I; cd01679
550537013692	active site
550537013693	dimer interface [polypeptide binding]; other site
550537013694	catalytic residues [active]
550537013695	effector binding site; other site
550537013696	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
550537013697	HMMPfam hit to PF08343, Ribonucleotide reductase N-terminal, score 4.8e-43
550537013698	HMMPfam hit to PF00317, Ribonucleotide reductase large subunit, N-terminal, score 4.3e-26
550537013699	HMMPfam hit to PF02867, Ribonucleotide reductase large subunit, C-terminal, score 2.3e-280
550537013700	PS00089 Ribonucleotide reductase large subunit signature.
550537013701	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
550537013702	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
550537013703	dimer interface [polypeptide binding]; other site
550537013704	putative radical transfer pathway; other site
550537013705	diiron center [ion binding]; other site
550537013706	tyrosyl radical; other site
550537013707	HMMPfam hit to PF00268, Ribonucleotide reductase, score 1.1e-131
550537013708	PS00368 Ribonucleotide reductase small subunit signature.
550537013709	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
550537013710	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
550537013711	Walker A/P-loop; other site
550537013712	ATP binding site [chemical binding]; other site
550537013713	Q-loop/lid; other site
550537013714	ABC transporter signature motif; other site
550537013715	Walker B; other site
550537013716	D-loop; other site
550537013717	H-loop/switch region; other site
550537013718	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
550537013719	HMMPfam hit to PF00005, ABC transporter related, score 1.2e-67
550537013720	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013721	PS00211 ABC transporters family signature.
550537013722	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 3.2e-11
550537013723	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
550537013724	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537013725	dimer interface [polypeptide binding]; other site
550537013726	conserved gate region; other site
550537013727	putative PBP binding loops; other site
550537013728	ABC-ATPase subunit interface; other site
550537013729	6 probable transmembrane helices predicted for SEN2655 by TMHMM2.0 at aa 94-116, 120-142, 149-171, 197-219, 272-294 and 298-320
550537013730	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1e-33
550537013731	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537013732	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
550537013733	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
550537013734	HMMPfam hit to PF04069, Substrate-binding region of ABC-type glycine betaine transport system, score 1.4e-59
550537013735	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013736	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
550537013737	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537013738	12 probable transmembrane helices predicted for SEN2657 by TMHMM2.0 at aa 11-33, 48-70, 77-94, 104-126, 133-155, 160-182, 217-239, 249-271, 278-295, 300-322, 335-357 and 362-384
550537013739	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 9.8e-42
550537013740	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013741	transcriptional repressor MprA; Provisional; Region: PRK10870
550537013742	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
550537013743	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 7.3e-27
550537013744	PS01117 Bacterial regulatory proteins, marR family signature.
550537013745	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
550537013746	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537013747	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537013748	1 probable transmembrane helix predicted for SEN2659 by TMHMM2.0 at aa 23-45
550537013749	HMMPfam hit to PF00529, Secretion protein HlyD, score 4.7e-85
550537013750	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
550537013751	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537013752	putative substrate translocation pore; other site
550537013753	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537013754	13 probable transmembrane helices predicted for SEN2660 by TMHMM2.0 at aa 13-35, 50-72, 79-101, 106-128, 140-162, 167-189, 201-218, 228-250, 270-292, 302-324, 336-353, 368-390 and 480-498
550537013755	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.7e-57
550537013756	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013757	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
550537013758	S-ribosylhomocysteinase; Provisional; Region: PRK02260
550537013759	HMMPfam hit to PF02664, S-ribosylhomocysteinase (LuxS), score 3.6e-114
550537013760	glutamate--cysteine ligase; Provisional; Region: PRK02107
550537013761	HMMPfam hit to PF04262, Glutamate--cysteine ligase, score 6.3e-285
550537013762	Predicted membrane protein [Function unknown]; Region: COG1238
550537013763	4 probable transmembrane helices predicted for SEN2664 by TMHMM2.0 at aa 15-37, 42-64, 84-106 and 118-140
550537013764	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
550537013765	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537013766	motif II; other site
550537013767	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 2.4e-33
550537013768	carbon storage regulator; Provisional; Region: PRK01712
550537013769	HMMPfam hit to PF02599, Carbon storage regulator, score 7.2e-35
550537013770	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
550537013771	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
550537013772	motif 1; other site
550537013773	active site
550537013774	motif 2; other site
550537013775	motif 3; other site
550537013776	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
550537013777	DHHA1 domain; Region: DHHA1; pfam02272
550537013778	HMMPfam hit to PF02272, Phosphoesterase, DHHA1, score 1.7e-22
550537013779	HMMPfam hit to PF07973, Threonyl/alanyl tRNA synthetase, SAD, score 1.2e-21
550537013780	HMMPfam hit to PF01411, Alanyl-tRNA synthetase, class IIc, score 0
550537013781	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537013782	recombination regulator RecX; Reviewed; Region: recX; PRK00117
550537013783	HMMPfam hit to PF02631, Regulatory protein RecX, score 1.2e-59
550537013784	recombinase A; Provisional; Region: recA; PRK09354
550537013785	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
550537013786	hexamer interface [polypeptide binding]; other site
550537013787	Walker A motif; other site
550537013788	ATP binding site [chemical binding]; other site
550537013789	Walker B motif; other site
550537013790	HMMPfam hit to PF00154, RecA, score 3.3e-253
550537013791	PS00321 recA signature.
550537013792	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013793	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013794	hypothetical protein; Validated; Region: PRK03661
550537013795	HMMPfam hit to PF02464, CinA, C-terminal, score 1.5e-97
550537013796	Transglycosylase SLT domain; Region: SLT_2; pfam13406
550537013797	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
550537013798	N-acetyl-D-glucosamine binding site [chemical binding]; other site
550537013799	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013800	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
550537013801	HMMPfam hit to PF03608, Phosphotransferase system, enzyme II sorbitol-specific factor, score 2.6e-142
550537013802	3 probable transmembrane helices predicted for SEN2673 by TMHMM2.0 at aa 26-48, 69-91 and 134-156
550537013803	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013804	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
550537013805	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
550537013806	Nucleoside recognition; Region: Gate; pfam07670
550537013807	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
550537013808	HMMPfam hit to PF03612, Sorbitol phosphotransferase enzyme II, N-terminal, score 6.7e-118
550537013809	PS00107 Protein kinases ATP-binding region signature.
550537013810	4 probable transmembrane helices predicted for SEN2674 by TMHMM2.0 at aa 181-203, 218-240, 247-269 and 300-322
550537013811	HMMPfam hit to PF07663, Sorbitol phosphotransferase enzyme II, C-terminal, score 1.6e-55
550537013812	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
550537013813	HMMPfam hit to PF03829, Phosphotransferase system, glucitol/sorbitol-specific IIA component, score 6.1e-69
550537013814	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
550537013815	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
550537013816	putative NAD(P) binding site [chemical binding]; other site
550537013817	active site
550537013818	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 7.3e-26
550537013819	PS00061 Short-chain dehydrogenases/reductases family signature.
550537013820	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
550537013821	HMMPfam hit to PF06923, Glucitol operon activator, score 2.7e-59
550537013822	1 probable transmembrane helix predicted for SEN2677 by TMHMM2.0 at aa 2-24
550537013823	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
550537013824	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
550537013825	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537013826	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 4.4e-25
550537013827	PS00894 Bacterial regulatory proteins, deoR family signature.
550537013828	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 1.7e-79
550537013829	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
550537013830	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
550537013831	putative active site [active]
550537013832	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
550537013833	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 4.7e-34
550537013834	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 1.6e-21
550537013835	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
550537013836	GAF domain; Region: GAF; pfam01590
550537013837	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537013838	Walker A motif; other site
550537013839	ATP binding site [chemical binding]; other site
550537013840	Walker B motif; other site
550537013841	arginine finger; other site
550537013842	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537013843	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 2.4e-144
550537013844	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537013845	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537013846	HMMPfam hit to PF01590, GAF, score 4.3e-13
550537013847	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
550537013848	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
550537013849	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
550537013850	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
550537013851	iron binding site [ion binding]; other site
550537013852	HMMPfam hit to PF00753, Beta-lactamase-like, score 8.1e-30
550537013853	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 2.2e-24
550537013854	HMMPfam hit to PF00301, Rubredoxin-type Fe(Cys)4 protein, score 4.3e-23
550537013855	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
550537013856	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537013857	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537013858	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 2.4e-27
550537013859	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 7.9e-28
550537013860	HydA maturation
550537013861	Acylphosphatase; Region: Acylphosphatase; pfam00708
550537013862	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
550537013863	HypF finger; Region: zf-HYPF; pfam07503
550537013864	HypF finger; Region: zf-HYPF; pfam07503
550537013865	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
550537013866	HMMPfam hit to PF01300, SUA5/yciO/yrdC, N-terminal, score 2.2e-71
550537013867	HMMPfam hit to PF07503, Zinc finger, HypF-type, score 3.1e-15
550537013868	HMMPfam hit to PF07503, Zinc finger, HypF-type, score 1.8e-16
550537013869	HMMPfam hit to PF00708, Acylphosphatase, score 5.1e-07
550537013870	PS00150 Acylphosphatase signature 1.
550537013871	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
550537013872	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
550537013873	PS00190 Cytochrome c family heme-binding site signature.
550537013874	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 7.5e-08
550537013875	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537013876	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.011
550537013878	1 probable transmembrane helix predicted for SEN2686 by TMHMM2.0 at aa 13-35
550537013879	Signal peptide predicted for SEN2686 by SignalP 2.0 HMM (Signal peptide probability 0.969) with cleavage site probability 0.846 between residues 30 and 31
550537013880	Hydrogenase 3 operon hycABCDEFGHI
550537013881	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
550537013882	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
550537013883	nickel binding site [ion binding]; other site
550537013884	HMMPfam hit to PF01750, Peptidase A31, hydrogen uptake protein, score 4.3e-36
550537013885	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
550537013886	HMMPfam hit to PF07450, Formate hydrogenlyase maturation HycH, score 1.4e-102
550537013887	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
550537013888	HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 kDa subunit, score 1.2e-52
550537013889	PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature.
550537013890	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
550537013891	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
550537013892	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.1e-08
550537013893	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537013894	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.1e-07
550537013895	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537013896	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
550537013897	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
550537013898	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
550537013899	HMMPfam hit to PF00346, NADH-ubiquinone oxidoreductase, chain 49kDa, score 2.9e-13
550537013900	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013901	HMMPfam hit to PF00374, Nickel-dependent hydrogenase, large subunit, score 5.9e-11
550537013902	PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature.
550537013903	HMMPfam hit to PF00329, NADH dehydrogenase (ubiquinone), 30 kDa subunit, score 1e-27
550537013904	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
550537013905	NADH dehydrogenase; Region: NADHdh; cl00469
550537013906	HMMPfam hit to PF00146, Respiratory-chain NADH dehydrogenase, subunit 1, score 3.3e-06
550537013907	7 probable transmembrane helices predicted for SEN2692 by TMHMM2.0 at aa 5-27, 62-84, 94-111, 132-154, 169-188, 252-274 and 289-306
550537013908	PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2.
550537013909	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013910	PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1.
550537013911	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
550537013912	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
550537013913	15 probable transmembrane helices predicted for SEN2693 by TMHMM2.0 at aa 4-26, 31-53, 73-95, 108-125, 129-148, 155-177, 197-219, 231-253, 257-279, 292-311, 326-348, 373-395, 415-437, 457-479 and 499-521
550537013914	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013915	HMMPfam hit to PF00361, NADH/Ubiquinone/plastoquinone (complex I), score 1e-28
550537013916	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
550537013917	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 4.5e-07
550537013918	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537013919	PS00190 Cytochrome c family heme-binding site signature.
550537013920	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
550537013921	hypABCDE, fhlA regulates the three hydrogenase operons
550537013922	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
550537013923	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
550537013924	HMMPfam hit to PF01155, Hydrogenase expression/synthesis, HypA, score 3.6e-56
550537013925	PS01249 Hydrogenases expression/synthesis hypA family signature.
550537013926	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
550537013927	HMMPfam hit to PF02492, Cobalamin (vitamin B12) biosynthesis CobW-like, score 2.5e-70
550537013928	hydrogenase assembly chaperone; Provisional; Region: PRK10409
550537013929	HMMPfam hit to PF01455, Hydrogenase expression/formation protein (HUPF/HYPC), score 3.9e-45
550537013930	PS01097 Hydrogenases expression/synthesis hupF/hypC family signature.
550537013931	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
550537013932	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
550537013933	HMMPfam hit to PF01924, Hydrogenase formation HypD protein, score 8.7e-260
550537013934	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
550537013935	dimerization interface [polypeptide binding]; other site
550537013936	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
550537013937	ATP binding site [chemical binding]; other site
550537013938	HMMPfam hit to PF00586, AIR synthase related protein, score 4.7e-40
550537013939	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal, score 1.9e-34
550537013940	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
550537013941	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
550537013942	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
550537013943	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537013944	Walker A motif; other site
550537013945	ATP binding site [chemical binding]; other site
550537013946	Walker B motif; other site
550537013947	arginine finger; other site
550537013948	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
550537013949	HMMPfam hit to PF01590, GAF, score 2.9e-18
550537013950	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 5.8e-148
550537013951	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537013952	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537013953	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 2.8e-06
550537013954	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
550537013955	Salmonella Pathogenicity Island 1: SPI-1
550537013956	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
550537013957	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
550537013958	metal binding site [ion binding]; metal-binding site
550537013959	1 probable transmembrane helix predicted for SEN2703 by TMHMM2.0 at aa 7-26
550537013960	HMMPfam hit to PF01297, Periplasmic solute binding protein, score 3.5e-123
550537013961	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
550537013962	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
550537013963	HMMPfam hit to PF00005, ABC transporter related, score 9.2e-48
550537013964	PS00017 ATP/GTP-binding site motif A (P-loop).
550537013965	PS00211 ABC transporters family signature.
550537013966	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
550537013967	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537013968	ABC-ATPase subunit  interface; other site
550537013969	dimer interface [polypeptide binding]; other site
550537013970	putative PBP binding regions; other site
550537013971	HMMPfam hit to PF00950, ABC-3, score 2.2e-106
550537013972	7 probable transmembrane helices predicted for SEN2705 by TMHMM2.0 at aa 15-37, 50-72, 92-114, 121-143, 182-204, 217-239 and 249-271
550537013973	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013974	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
550537013975	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
550537013976	ABC-ATPase subunit  interface; other site
550537013977	dimer interface [polypeptide binding]; other site
550537013978	putative PBP binding regions; other site
550537013979	HMMPfam hit to PF00950, ABC-3, score 6.4e-105
550537013980	8 probable transmembrane helices predicted for SEN2706 by TMHMM2.0 at aa 21-43, 58-80, 93-115, 130-152, 169-191, 196-215, 222-244 and 248-267
550537013981	effector protein YopJ; Provisional; Region: PRK15371
550537013982	HMMPfam hit to PF03421, Serine/Threonine acetyltransferase, YopJ, score 3.6e-89
550537013983	transcriptional activator SprB; Provisional; Region: PRK15320
550537013984	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
550537013985	transcriptional regulator SirC; Provisional; Region: PRK15044
550537013986	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537013987	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 3e-08
550537013988	PS00041 Bacterial regulatory proteins, araC family signature.
550537013989	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
550537013990	invasion protein OrgB; Provisional; Region: PRK15322
550537013991	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
550537013992	invasion protein OrgA; Provisional; Region: PRK15323
550537013993	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
550537013994	1 probable transmembrane helix predicted for SEN2713 by TMHMM2.0 at aa 207-229
550537013995	HMMPfam hit to PF01514, Secretory protein YscJ/FliF, score 1.5e-81
550537013996	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537013997	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
550537013998	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
550537013999	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
550537014000	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
550537014001	1 probable transmembrane helix predicted for SEN2716 by TMHMM2.0 at aa 141-163
550537014002	transcriptional regulator HilD; Provisional; Region: PRK15185
550537014003	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537014004	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 8.3e-05
550537014005	PS00041 Bacterial regulatory proteins, araC family signature.
550537014006	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 7e-12
550537014007	invasion protein regulator; Provisional; Region: PRK12370
550537014008	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537014009	DNA binding site [nucleotide binding]
550537014010	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
550537014011	binding surface
550537014012	TPR motif; other site
550537014013	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 4.1e-20
550537014014	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 2.4e-05
550537014015	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
550537014016	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
550537014017	N-acetyl-D-glucosamine binding site [chemical binding]; other site
550537014018	catalytic residue [active]
550537014019	HMMPfam hit to PF01464, Lytic transglycosylase-like, catalytic, score 8.1e-50
550537014020	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
550537014021	SicP binding; Region: SicP-binding; pfam09119
550537014022	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
550537014023	switch II binding region; other site
550537014024	Rac1 P-loop interaction site [polypeptide binding]; other site
550537014025	GTP binding residues [chemical binding]; other site
550537014026	switch I binding region; other site
550537014027	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
550537014028	active site
550537014029	HMMPfam hit to PF00102, Protein-tyrosine phosphatase, receptor/non-receptor type, score 1.1e-23
550537014030	PS00383 Tyrosine specific protein phosphatases active site.
550537014031	HMMPfam hit to PF03545, Yersinia virulence determinant YopE, C-terminal, score 2.1e-47
550537014032	HMMPfam hit to PF09119, SicP binding, score 3e-57
550537014033	chaperone protein SicP; Provisional; Region: PRK15329
550537014034	HMMPfam hit to PF05932, Tir chaperone, score 1e-06
550537014035	putative acyl carrier protein IacP; Validated; Region: PRK08172
550537014036	HMMPfam hit to PF00550, Phosphopantetheine-binding, score 3.7e-05
550537014037	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
550537014038	HMMPfam hit to PF09052, Salmonella invasion protein A, score 0
550537014039	cell invasion protein SipD; Provisional; Region: PRK15330
550537014040	HMMPfam hit to PF06511, Invasion plasmid antigen IpaD, score 3.5e-272
550537014041	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
550537014042	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
550537014043	HMMPfam hit to PF03518, Salmonella/Shigella invasin protein B, score 5e-280
550537014044	2 probable transmembrane helices predicted for SEN2726 by TMHMM2.0 at aa 320-342 and 408-430
550537014045	chaperone protein SicA; Provisional; Region: PRK15331
550537014046	Tetratricopeptide repeat; Region: TPR_3; pfam07720
550537014047	Tetratricopeptide repeat; Region: TPR_3; pfam07720
550537014048	HMMPfam hit to PF07720, Tetratricopeptide TPR-3, score 1.4e-11
550537014049	HMMPfam hit to PF07720, Tetratricopeptide TPR-3, score 3.5e-13
550537014050	type III secretion system protein SpaS; Validated; Region: PRK08156
550537014051	HMMPfam hit to PF01312, Type III secretion exporter, score 2e-166
550537014052	4 probable transmembrane helices predicted for SEN2728 by TMHMM2.0 at aa 29-51, 72-94, 136-153 and 178-200
550537014053	type III secretion system protein SpaR; Provisional; Region: PRK15332
550537014054	HMMPfam hit to PF01311, Type III secretion system inner membrane R protein, score 1.8e-109
550537014055	6 probable transmembrane helices predicted for SEN2729 by TMHMM2.0 at aa 10-32, 37-59, 79-101, 128-150, 181-203 and 210-232
550537014056	type III secretion system protein SpaQ; Provisional; Region: PRK15333
550537014057	HMMPfam hit to PF01313, Bacterial export protein FliQ, family 3, score 8e-43
550537014058	2 probable transmembrane helices predicted for SEN2730 by TMHMM2.0 at aa 12-34 and 49-71
550537014059	PS00888 Cyclic nucleotide-binding domain signature 1.
550537014060	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
550537014061	HMMPfam hit to PF00813, Type III secretion system inner membrane P protein, score 1e-124
550537014062	PS01061 Flagella transport protein fliP family signature 2.
550537014063	3 probable transmembrane helices predicted for SEN2731 by TMHMM2.0 at aa 15-37, 50-69 and 161-183
550537014064	PS01060 Flagella transport protein fliP family signature 1.
550537014065	type III secretion system protein SpaO; Validated; Region: PRK08158
550537014066	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
550537014067	HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) protein, score 3.1e-27
550537014068	antigen presentation protein SpaN; Provisional; Region: PRK15334
550537014069	Surface presentation of antigens protein; Region: SPAN; pfam02510
550537014070	HMMPfam hit to PF02510, Salmonella invasion protein InvJ, score 6.9e-284
550537014071	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
550537014072	HMMPfam hit to PF02090, Salmonella surface presentation of antigen M protein, score 8.4e-117
550537014073	ATP synthase SpaL; Validated; Region: PRK08149
550537014074	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
550537014075	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
550537014076	Walker A motif; other site
550537014077	ATP binding site [chemical binding]; other site
550537014078	Walker B motif; other site
550537014079	HMMPfam hit to PF00006, ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding, score 2.2e-118
550537014080	PS00152 ATP synthase alpha and beta subunits signature.
550537014081	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014082	HMMPfam hit to PF02874, ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal, score 2.7e-05
550537014083	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
550537014084	HMMPfam hit to PF03519, Invasion protein B, score 2.6e-55
550537014085	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
550537014086	type III secretion system protein InvA; Provisional; Region: PRK15337
550537014087	HMMPfam hit to PF00771, Bacterial type III secretion FHIPEP, score 0
550537014088	8 probable transmembrane helices predicted for SEN2737 by TMHMM2.0 at aa 13-30, 35-57, 69-91, 106-128, 197-219, 239-261, 274-291 and 296-315
550537014089	PS00994 Bacterial export FHIPEP family signature.
550537014090	type III secretion system regulator InvE; Provisional; Region: PRK15338
550537014091	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
550537014092	HMMPfam hit to PF02523, Salmonella/Shigella invasion protein E, score 4.7e-293
550537014093	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
550537014094	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
550537014095	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
550537014096	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
550537014097	HMMPfam hit to PF00263, Bacterial type II and III secretion system protein, score 8.7e-72
550537014098	PS00875 Bacterial type II secretion system protein D signature.
550537014099	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014100	HMMPfam hit to PF03958, NolW-like, score 5.1e-13
550537014101	HMMPfam hit to PF03958, NolW-like, score 1.8e-10
550537014102	transcriptional regulator InvF; Provisional; Region: PRK15340
550537014103	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.0014
550537014104	PS00041 Bacterial regulatory proteins, araC family signature.
550537014105	InvH outer membrane lipoprotein; Region: InvH; pfam04741
550537014106	HMMPfam hit to PF04741, InvH outer membrane lipoprotein, score 1.4e-119
550537014107	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014109	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
550537014110	HMMPfam hit to PF08681, Protein of unknown function DUF1778, score 5.6e-34
550537014111	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 0.0056
550537014112	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
550537014113	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
550537014114	active site
550537014115	metal binding site [ion binding]; metal-binding site
550537014116	HMMPfam hit to PF00149, Metallophosphoesterase, score 2.1e-18
550537014117	2 probable transmembrane helices predicted for SEN2746 by TMHMM2.0 at aa 27-49 and 59-81
550537014118	2 probable transmembrane helices predicted for SEN2746A by TMHMM2.0 at aa 21-43 and 47-69
550537014119	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
550537014120	MutS domain I; Region: MutS_I; pfam01624
550537014121	MutS domain II; Region: MutS_II; pfam05188
550537014122	MutS domain III; Region: MutS_III; pfam05192
550537014123	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
550537014124	Walker A/P-loop; other site
550537014125	ATP binding site [chemical binding]; other site
550537014126	Q-loop/lid; other site
550537014127	ABC transporter signature motif; other site
550537014128	Walker B; other site
550537014129	D-loop; other site
550537014130	H-loop/switch region; other site
550537014131	HMMPfam hit to PF01624, DNA mismatch repair protein MutS, N-terminal, score 7.2e-69
550537014132	HMMPfam hit to PF05188, MutS II, score 5.5e-50
550537014133	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537014134	HMMPfam hit to PF05192, MutS III, score 3e-99
550537014135	HMMPfam hit to PF05190, MutS IV, score 1.3e-41
550537014136	HMMPfam hit to PF00488, DNA mismatch repair protein MutS, C-terminal, score 7.1e-175
550537014137	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014138	PS00486 DNA mismatch repair proteins mutS family signature.
550537014139	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
550537014140	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537014141	Major Facilitator Superfamily; Region: MFS_1; pfam07690
550537014142	putative substrate translocation pore; other site
550537014143	12 probable transmembrane helices predicted for SEN2750 by TMHMM2.0 at aa 7-29, 42-64, 69-88, 98-120, 129-151, 161-183, 203-225, 235-257, 270-289, 299-321, 342-361 and 366-388
550537014144	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5.8e-47
550537014145	PS00217 Sugar transport proteins signature 2.
550537014146	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537014147	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537014148	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
550537014149	putative effector binding pocket; other site
550537014150	dimerization interface [polypeptide binding]; other site
550537014151	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.8e-16
550537014152	PS00044 Bacterial regulatory proteins, lysR family signature.
550537014153	HMMPfam hit to PF03466, LysR, substrate-binding, score 4.4e-45
550537014154	GntP family permease; Region: GntP_permease; pfam02447
550537014155	fructuronate transporter; Provisional; Region: PRK10034; cl15264
550537014156	12 probable transmembrane helices predicted for SEN2752 by TMHMM2.0 at aa 4-23, 30-48, 58-80, 104-126, 176-198, 241-263, 278-300, 320-337, 357-379, 392-414, 434-456 and 463-485
550537014157	HMMPfam hit to PF02447, Gluconate transporter, score 2.3e-201
550537014158	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014159	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
550537014160	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
550537014161	putative NAD(P) binding site [chemical binding]; other site
550537014162	active site
550537014163	putative substrate binding site [chemical binding]; other site
550537014164	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 7.9e-22
550537014165	hypothetical protein; Provisional; Region: PRK09989
550537014166	HMMPfam hit to PF01261, Xylose isomerase-type TIM barrel, score 6e-52
550537014167	putative aldolase; Validated; Region: PRK08130
550537014168	intersubunit interface [polypeptide binding]; other site
550537014169	active site
550537014170	Zn2+ binding site [ion binding]; other site
550537014171	HMMPfam hit to PF00596, Class II aldolase/adducin, N-terminal, score 4.9e-65
550537014172	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014173	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
550537014174	HMMPfam hit to PF07005, Type III effector Hrp-dependent outers, score 5.9e-140
550537014175	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
550537014176	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
550537014177	HMMPfam hit to PF03446, 6-phosphogluconate dehydrogenase, NAD-binding, score 5.3e-58
550537014178	PS00895 3-hydroxyisobutyrate dehydrogenase signature.
550537014179	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537014180	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537014181	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537014182	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 3.1e-18
550537014183	PS00894 Bacterial regulatory proteins, deoR family signature.
550537014184	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 1.5e-35
550537014185	MarR family; Region: MarR_2; cl17246
550537014186	Transcriptional regulators [Transcription]; Region: MarR; COG1846
550537014187	HMMPfam hit to PF01047, Bacterial regulatory protein, MarR, score 4e-17
550537014188	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
550537014189	Flavoprotein; Region: Flavoprotein; pfam02441
550537014190	HMMPfam hit to PF02441, Flavoprotein, score 2.7e-47
550537014191	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
550537014192	HMMPfam hit to PF01977, Carboxylyase-related, score 8.7e-157
550537014193	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
550537014194	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
550537014195	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
550537014196	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
550537014197	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
550537014198	DNA binding residues [nucleotide binding]
550537014199	HMMPfam hit to PF04545, RNA polymerase sigma-70 region 4, score 1.5e-20
550537014200	PS00716 Sigma-70 factors family signature 2.
550537014201	HMMPfam hit to PF04539, RNA polymerase sigma-70 region 3, score 1.3e-27
550537014202	HMMPfam hit to PF04542, RNA polymerase sigma-70 region 2, score 5.2e-27
550537014203	PS00715 Sigma-70 factors family signature 1.
550537014204	HMMPfam hit to PF00140, RNA polymerase sigma-70 region 1.2, score 3.1e-13
550537014205	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
550537014206	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537014207	Peptidase family M23; Region: Peptidase_M23; pfam01551
550537014208	HMMPfam hit to PF01551, Peptidase M23B, score 3.7e-54
550537014209	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 7.9e-13
550537014210	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014211	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
550537014212	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537014213	S-adenosylmethionine binding site [chemical binding]; other site
550537014214	HMMPfam hit to PF01135, Protein-L-isoaspartate(D-aspartate) O-methyltransferase, score 2.2e-124
550537014215	PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature.
550537014216	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537014217	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
550537014218	HMMPfam hit to PF01975, Survival protein SurE, score 3.4e-108
550537014219	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
550537014220	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
550537014221	Permutation of conserved domain; other site
550537014222	active site
550537014223	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
550537014224	HMMPfam hit to PF01142, tRNA pseudouridine synthase D, score 2.1e-169
550537014225	PS01268 Uncharacterized protein family UPF0024 signature.
550537014226	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
550537014227	homotrimer interaction site [polypeptide binding]; other site
550537014228	zinc binding site [ion binding]; other site
550537014229	CDP-binding sites; other site
550537014230	HMMPfam hit to PF02542, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core, score 3.3e-102
550537014231	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
550537014232	substrate binding site; other site
550537014233	dimer interface; other site
550537014234	HMMPfam hit to PF01128, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, score 5.7e-142
550537014235	PS01295 Uncharacterized protein family UPF0007 signature.
550537014236	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
550537014237	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
550537014238	HMMPfam hit to PF04977, Septum formation initiator, score 2.3e-35
550537014239	1 probable transmembrane helix predicted for SEN2770 by TMHMM2.0 at aa 4-21
550537014240	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
550537014241	3 probable transmembrane helices predicted for SEN2771 by TMHMM2.0 at aa 34-56, 63-85 and 95-117
550537014242	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
550537014243	ligand-binding site [chemical binding]; other site
550537014244	HMMPfam hit to PF01583, Adenylylsulphate kinase, C-terminal, score 2.5e-110
550537014245	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014246	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
550537014247	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
550537014248	CysD dimerization site [polypeptide binding]; other site
550537014249	G1 box; other site
550537014250	putative GEF interaction site [polypeptide binding]; other site
550537014251	GTP/Mg2+ binding site [chemical binding]; other site
550537014252	Switch I region; other site
550537014253	G2 box; other site
550537014254	G3 box; other site
550537014255	Switch II region; other site
550537014256	G4 box; other site
550537014257	G5 box; other site
550537014258	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
550537014259	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
550537014260	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 1.7e-08
550537014261	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 9.6e-71
550537014262	PS00301 GTP-binding elongation factors signature.
550537014263	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014264	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
550537014265	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
550537014266	Active Sites [active]
550537014267	HMMPfam hit to PF01507, Phosphoadenosine phosphosulphate reductase, score 1.3e-143
550537014268	PS00215 Mitochondrial energy transfer proteins signature.
550537014269	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
550537014270	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
550537014271	metal binding site [ion binding]; metal-binding site
550537014272	HMMPfam hit to PF04389, Peptidase M28, score 2.3e-37
550537014273	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
550537014274	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
550537014275	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
550537014276	HMMPfam hit to PF08798, CRISPR-associated protein, CT1974, score 4.3e-102
550537014277	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
550537014278	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
550537014279	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
550537014280	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
550537014281	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
550537014282	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
550537014283	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
550537014284	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
550537014285	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
550537014286	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
550537014287	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
550537014288	Active Sites [active]
550537014289	HMMPfam hit to PF01507, Phosphoadenosine phosphosulphate reductase, score 7.9e-87
550537014290	sulfite reductase subunit beta; Provisional; Region: PRK13504
550537014291	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
550537014292	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
550537014293	PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site.
550537014294	HMMPfam hit to PF03460, Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like, score 2.2e-18
550537014295	HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S region, score 3.3e-59
550537014296	HMMPfam hit to PF03460, Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like, score 4.2e-19
550537014297	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
550537014298	Flavodoxin; Region: Flavodoxin_1; pfam00258
550537014299	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
550537014300	FAD binding pocket [chemical binding]; other site
550537014301	FAD binding motif [chemical binding]; other site
550537014302	catalytic residues [active]
550537014303	NAD binding pocket [chemical binding]; other site
550537014304	phosphate binding motif [ion binding]; other site
550537014305	beta-alpha-beta structure motif; other site
550537014306	HMMPfam hit to PF00175, Oxidoreductase FAD/NAD(P)-binding, score 7.7e-35
550537014307	HMMPfam hit to PF00667, FAD-binding, score 1.5e-78
550537014308	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 4.3e-41
550537014309	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
550537014310	active site
550537014311	HMMPfam hit to PF01242, 6-pyruvoyl tetrahydropterin synthase and hypothetical protein, score 4.8e-80
550537014312	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
550537014313	HMMPfam hit to PF00753, Beta-lactamase-like, score 4.4e-16
550537014314	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
550537014315	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
550537014316	HMMPfam hit to PF04055, Radical SAM, score 0.018
550537014317	enolase; Provisional; Region: eno; PRK00077
550537014318	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
550537014319	dimer interface [polypeptide binding]; other site
550537014320	metal binding site [ion binding]; metal-binding site
550537014321	substrate binding pocket [chemical binding]; other site
550537014322	HMMPfam hit to PF00113, Enolase, score 2.5e-190
550537014323	PS00164 Enolase signature.
550537014324	HMMPfam hit to PF03952, Enolase, score 1e-69
550537014325	CTP synthetase; Validated; Region: pyrG; PRK05380
550537014326	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
550537014327	Catalytic site [active]
550537014328	active site
550537014329	UTP binding site [chemical binding]; other site
550537014330	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
550537014331	active site
550537014332	putative oxyanion hole; other site
550537014333	catalytic triad [active]
550537014334	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.5e-80
550537014335	PS00442 Glutamine amidotransferases class-I active site.
550537014336	HMMPfam hit to PF06418, CTP synthase, score 8e-215
550537014337	1 probable transmembrane helix predicted for SEN2792 by TMHMM2.0 at aa 7-29
550537014338	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
550537014339	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
550537014340	homodimer interface [polypeptide binding]; other site
550537014341	metal binding site [ion binding]; metal-binding site
550537014342	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
550537014343	homodimer interface [polypeptide binding]; other site
550537014344	active site
550537014345	putative chemical substrate binding site [chemical binding]; other site
550537014346	metal binding site [ion binding]; metal-binding site
550537014347	HMMPfam hit to PF03819, NTP pyrophosphohydrolase MazG,  catalytic core, score 8.5e-05
550537014348	HMMPfam hit to PF03819, NTP pyrophosphohydrolase MazG,  catalytic core, score 4e-43
550537014349	fimbrial operon ste
550537014350	fimbrial protein SteA; Provisional; Region: PRK15261
550537014351	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 5e-18
550537014352	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014353	putative fimbrial outer membrane usher protein SteB; Provisional; Region: PRK15273
550537014354	PapC N-terminal domain; Region: PapC_N; pfam13954
550537014355	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537014356	PapC C-terminal domain; Region: PapC_C; pfam13953
550537014357	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 1.9e-302
550537014358	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537014359	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
550537014360	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537014361	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537014362	1 probable transmembrane helix predicted for SEN2796 by TMHMM2.0 at aa 12-29
550537014363	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 2.7e-43
550537014364	PS00635 Gram-negative pili assembly chaperone signature.
550537014365	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 0.00012
550537014366	putative fimbrial protein SteD; Provisional; Region: PRK15275
550537014367	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.0011
550537014368	putative fimbrial subunit SteE; Provisional; Region: PRK15276
550537014369	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.0069
550537014370	fimbrial protein SteF; Provisional; Region: PRK15260
550537014371	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 5.2e-19
550537014372	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
550537014373	HD domain; Region: HD_4; pfam13328
550537014374	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
550537014375	synthetase active site [active]
550537014376	NTP binding site [chemical binding]; other site
550537014377	metal binding site [ion binding]; metal-binding site
550537014378	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
550537014379	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
550537014380	HMMPfam hit to PF01842, Amino acid-binding ACT, score 1.8e-09
550537014381	HMMPfam hit to PF02824, TGS, score 1.7e-30
550537014382	HMMPfam hit to PF04607, RelA/SpoT, score 1.8e-47
550537014383	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
550537014384	TRAM domain; Region: TRAM; pfam01938
550537014385	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537014386	S-adenosylmethionine binding site [chemical binding]; other site
550537014387	HMMPfam hit to PF05958, (Uracil-5)-methyltransferase, score 3.4e-10
550537014388	PS01231 RNA methyltransferase trmA family signature 2.
550537014389	PS01230 RNA methyltransferase trmA family signature 1.
550537014390	HMMPfam hit to PF01938, Deoxyribonuclease/rho motif-related TRAM, score 3.8e-15
550537014391	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
550537014392	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
550537014393	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537014394	dimerization interface [polypeptide binding]; other site
550537014395	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537014396	dimer interface [polypeptide binding]; other site
550537014397	phosphorylation site [posttranslational modification]
550537014398	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537014399	ATP binding site [chemical binding]; other site
550537014400	Mg2+ binding site [ion binding]; other site
550537014401	G-X-G motif; other site
550537014402	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
550537014403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537014404	active site
550537014405	phosphorylation site [posttranslational modification]
550537014406	intermolecular recognition site; other site
550537014407	dimerization interface [polypeptide binding]; other site
550537014408	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
550537014409	putative binding surface; other site
550537014410	active site
550537014411	2 probable transmembrane helices predicted for SEN2803 by TMHMM2.0 at aa 10-32 and 177-199
550537014412	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1.8e-13
550537014413	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.6e-27
550537014414	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2.7e-43
550537014415	HMMPfam hit to PF00072, Response regulator receiver, score 8.2e-46
550537014416	HMMPfam hit to PF01627, Hpt, score 1.6e-17
550537014417	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
550537014418	HMMPfam hit to PF02595, Glycerate kinase, score 5.2e-241
550537014419	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
550537014420	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
550537014421	active site
550537014422	tetramer interface [polypeptide binding]; other site
550537014423	PS00294 Prenyl group binding site (CAAX box).
550537014424	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 1.8e-21
550537014425	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
550537014426	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
550537014427	active site
550537014428	tetramer interface [polypeptide binding]; other site
550537014429	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 7e-24
550537014430	PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1.
550537014431	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537014432	D-galactonate transporter; Region: 2A0114; TIGR00893
550537014433	putative substrate translocation pore; other site
550537014434	12 probable transmembrane helices predicted for SEN2807 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 110-132, 152-174, 179-201, 256-278, 293-315, 328-348, 352-374, 387-409 and 414-436
550537014435	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 7.9e-65
550537014436	flavodoxin; Provisional; Region: PRK08105
550537014437	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 9.1e-32
550537014438	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
550537014439	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
550537014440	probable active site [active]
550537014441	HMMPfam hit to PF00849, Pseudouridine synthase, score 2.5e-54
550537014442	PS01129 Rlu family of pseudouridine synthase signature.
550537014443	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
550537014444	HMMPfam hit to PF04287, Protein of unknown function DUF446, score 1.5e-54
550537014445	SecY interacting protein Syd; Provisional; Region: PRK04968
550537014446	HMMPfam hit to PF07348, Syd, score 9.4e-119
550537014447	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
550537014448	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
550537014449	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
550537014450	HMMPfam hit to PF01227, GTP cyclohydrolase I, score 8.1e-08
550537014451	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
550537014452	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
550537014453	HMMPfam hit to PF03641, Conserved hypothetical protein CHP00730, score 2.4e-56
550537014454	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
550537014455	serine transporter; Region: stp; TIGR00814
550537014456	11 probable transmembrane helices predicted for SEN2814 by TMHMM2.0 at aa 24-41, 45-67, 103-125, 140-157, 164-186, 206-228, 249-271, 300-322, 351-373, 377-394 and 406-428
550537014457	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014458	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
550537014459	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
550537014460	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
550537014461	HMMPfam hit to PF03315, Serine dehydratase beta chain, score 4.6e-106
550537014462	HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 1.1e-202
550537014463	flap endonuclease-like protein; Provisional; Region: PRK09482
550537014464	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
550537014465	active site
550537014466	metal binding site 1 [ion binding]; metal-binding site
550537014467	putative 5' ssDNA interaction site; other site
550537014468	metal binding site 3; metal-binding site
550537014469	metal binding site 2 [ion binding]; metal-binding site
550537014470	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
550537014471	putative DNA binding site [nucleotide binding]; other site
550537014472	putative metal binding site [ion binding]; other site
550537014473	HMMPfam hit to PF02739, 5'-3' exonuclease, score 8.5e-21
550537014474	HMMPfam hit to PF01367, 5'-3' exonuclease, score 4.9e-27
550537014475	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
550537014476	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
550537014477	dimer interface [polypeptide binding]; other site
550537014478	active site
550537014479	metal binding site [ion binding]; metal-binding site
550537014480	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 4.3e-203
550537014481	PS00060 Iron-containing alcohol dehydrogenases signature 2.
550537014482	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537014483	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
550537014484	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
550537014485	intersubunit interface [polypeptide binding]; other site
550537014486	active site
550537014487	Zn2+ binding site [ion binding]; other site
550537014488	HMMPfam hit to PF00596, Class II aldolase/adducin, N-terminal, score 1.6e-75
550537014489	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014490	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
550537014491	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537014492	putative substrate translocation pore; other site
550537014493	12 probable transmembrane helices predicted for SEN2819A by TMHMM2.0 at aa 29-46, 66-88, 93-115, 125-147, 160-182, 217-239, 265-287, 297-319, 332-351, 356-378, 387-409 and 419-436
550537014494	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.4e-19
550537014495	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014496	L-fucose isomerase; Provisional; Region: fucI; PRK10991
550537014497	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
550537014498	hexamer (dimer of trimers) interface [polypeptide binding]; other site
550537014499	trimer interface [polypeptide binding]; other site
550537014500	substrate binding site [chemical binding]; other site
550537014501	Mn binding site [ion binding]; other site
550537014502	HMMPfam hit to PF07881, L-fucose isomerase, N-terminal-1, score 3.7e-129
550537014503	HMMPfam hit to PF07882, L-fucose isomerase, N-terminal-2, score 2.9e-125
550537014504	HMMPfam hit to PF02952, L-fucose isomerase-like, C-terminal, score 5.9e-118
550537014505	L-fuculokinase; Provisional; Region: PRK10331
550537014506	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
550537014507	nucleotide binding site [chemical binding]; other site
550537014508	HMMPfam hit to PF00370, Carbohydrate kinase, FGGY, score 1e-111
550537014509	PS00933 FGGY family of carbohydrate kinases signature 1.
550537014510	HMMPfam hit to PF02782, Carbohydrate kinase, FGGY, score 3.8e-77
550537014511	PS00445 FGGY family of carbohydrate kinases signature 2.
550537014512	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
550537014513	HMMPfam hit to PF05025, RbsD or FucU transport, score 2.8e-59
550537014514	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
550537014515	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
550537014516	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537014517	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 1.5e-22
550537014518	PS00894 Bacterial regulatory proteins, deoR family signature.
550537014519	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 7.5e-71
550537014520	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
550537014521	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
550537014522	HMMPfam hit to PF01728, Ribosomal RNA methyltransferase RrmJ/FtsJ, score 5.1e-07
550537014523	hypothetical protein; Provisional; Region: PRK10873
550537014524	4 probable transmembrane helices predicted for SEN2825 by TMHMM2.0 at aa 5-27, 37-59, 66-88 and 98-120
550537014525	HMMPfam hit to PF04241, Protein of unknown function DUF423, score 3.4e-54
550537014526	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
550537014527	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537014528	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
550537014529	dimerization interface [polypeptide binding]; other site
550537014530	substrate binding pocket [chemical binding]; other site
550537014531	HMMPfam hit to PF03466, LysR, substrate-binding, score 3e-47
550537014532	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 8.5e-22
550537014533	PS00044 Bacterial regulatory proteins, lysR family signature.
550537014534	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
550537014535	HMMPfam hit to PF06004, Protein of unknown function DUF903, bacterial, score 1.1e-44
550537014536	1 probable transmembrane helix predicted for SEN2827 by TMHMM2.0 at aa 5-27
550537014537	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014538	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
550537014539	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
550537014540	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537014541	catalytic residue [active]
550537014542	HMMPfam hit to PF00266, Aminotransferase, class V, score 9.2e-194
550537014543	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014544	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
550537014545	CsdA-binding activator; Provisional; Region: PRK15019
550537014546	HMMPfam hit to PF02657, Fe-S metabolism associated SufE, score 4.2e-62
550537014547	Predicted permeases [General function prediction only]; Region: RarD; COG2962
550537014548	10 probable transmembrane helices predicted for SEN2830 by TMHMM2.0 at aa 7-29, 34-56, 72-93, 97-119, 124-146, 150-167, 174-196, 206-228, 235-257 and 262-284
550537014549	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 1.9e-05
550537014550	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014551	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
550537014552	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
550537014553	putative ATP binding site [chemical binding]; other site
550537014554	putative substrate interface [chemical binding]; other site
550537014555	1 probable transmembrane helix predicted for SEN2831 by TMHMM2.0 at aa 235-257
550537014556	HMMPfam hit to PF00899, UBA/THIF-type NAD/FAD binding fold, score 1.5e-54
550537014557	murein transglycosylase A; Provisional; Region: mltA; PRK11162
550537014558	murein hydrolase B; Provisional; Region: PRK10760; cl17906
550537014559	MltA specific insert domain; Region: MltA; pfam03562
550537014560	3D domain; Region: 3D; pfam06725
550537014561	HMMPfam hit to PF06725, 3D, score 1.2e-35
550537014562	HMMPfam hit to PF03562, MltA, score 3.1e-77
550537014563	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014564	AMIN domain; Region: AMIN; pfam11741
550537014565	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
550537014566	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
550537014567	active site
550537014568	metal binding site [ion binding]; metal-binding site
550537014569	HMMPfam hit to PF01520, Cell wall hydrolase/autolysin, catalytic, score 2e-108
550537014570	N-acetylglutamate synthase; Validated; Region: PRK05279
550537014571	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
550537014572	putative feedback inhibition sensing region; other site
550537014573	putative nucleotide binding site [chemical binding]; other site
550537014574	putative substrate binding site [chemical binding]; other site
550537014575	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537014576	Coenzyme A binding pocket [chemical binding]; other site
550537014577	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 4.5e-36
550537014578	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 2.1e-10
550537014579	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
550537014580	AAA domain; Region: AAA_30; pfam13604
550537014581	Family description; Region: UvrD_C_2; pfam13538
550537014582	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014583	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
550537014584	HMMPfam hit to PF00580, DNA helicase, UvrD/REP type, score 2.8e-168
550537014585	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014586	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537014587	protease3; Provisional; Region: PRK15101
550537014588	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
550537014589	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
550537014590	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
550537014591	HMMPfam hit to PF05193, Peptidase M16, C-terminal, score 5.4e-19
550537014592	HMMPfam hit to PF05193, Peptidase M16, C-terminal, score 1.1e-26
550537014593	HMMPfam hit to PF00675, Peptidase M16, N-terminal, score 1.4e-54
550537014594	PS00143 Insulinase family, zinc-binding region signature.
550537014595	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
550537014596	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
550537014597	HMMPfam hit to PF04257, Exodeoxyribonuclease V, RecC subunit, score 0
550537014598	hypothetical protein; Provisional; Region: PRK10332
550537014599	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
550537014600	1 probable transmembrane helix predicted for SEN2839 by TMHMM2.0 at aa 15-37
550537014601	HMMPfam hit to PF07963, Prepilin-type cleavage/methylation, N-terminal, score 0.0023
550537014602	PS00409 Prokaryotic N-terminal methylation site.
550537014603	hypothetical protein; Provisional; Region: PRK11521
550537014604	PS00294 Prenyl group binding site (CAAX box).
550537014605	1 probable transmembrane helix predicted for SEN2840 by TMHMM2.0 at aa 10-27
550537014606	hypothetical protein; Provisional; Region: PRK10557
550537014607	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
550537014608	HMMPfam hit to PF07963, Prepilin-type cleavage/methylation, N-terminal, score 0.0031
550537014609	PS00409 Prokaryotic N-terminal methylation site.
550537014610	1 probable transmembrane helix predicted for SEN2841 by TMHMM2.0 at aa 7-26
550537014611	hypothetical protein; Provisional; Region: PRK10506
550537014612	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
550537014613	1 probable transmembrane helix predicted for SEN2842 by TMHMM2.0 at aa 7-29
550537014614	PS00409 Prokaryotic N-terminal methylation site.
550537014615	thymidylate synthase; Reviewed; Region: thyA; PRK01827
550537014616	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
550537014617	dimerization interface [polypeptide binding]; other site
550537014618	active site
550537014619	HMMPfam hit to PF00303, Thymidylate synthase, C-terminal, score 2e-151
550537014620	PS00091 Thymidylate synthase active site.
550537014621	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
550537014622	HMMPfam hit to PF01790, Prolipoprotein diacylglyceryl transferase, score 1.4e-144
550537014623	5 probable transmembrane helices predicted for SEN2844 by TMHMM2.0 at aa 15-37, 58-80, 95-117, 223-245 and 260-282
550537014624	PS01311 Prolipoprotein diacylglyceryl transferase signature.
550537014625	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
550537014626	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
550537014627	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
550537014628	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
550537014629	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
550537014630	HMMPfam hit to PF02896, PEP-utilizing enzyme, score 1.2e-162
550537014631	PS00742 PEP-utilizing enzymes signature 2.
550537014632	HMMPfam hit to PF00391, PEP-utilising enzyme, mobile region, score 4.7e-23
550537014633	PS00370 PEP-utilizing enzymes phosphorylation site signature.
550537014634	HMMPfam hit to PF05524, Phosphotransferase system, PEP-utilising enzyme, N-terminal, score 1.3e-43
550537014635	HMMPfam hit to PF01590, GAF, score 1.1e-26
550537014636	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
550537014637	putative active site [active]
550537014638	Ap4A binding site [chemical binding]; other site
550537014639	nudix motif; other site
550537014640	putative metal binding site [ion binding]; other site
550537014641	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 7.7e-31
550537014642	PS00893 mutT domain signature.
550537014643	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
550537014644	putative DNA-binding cleft [nucleotide binding]; other site
550537014645	putative DNA clevage site; other site
550537014646	molecular lever; other site
550537014647	HMMPfam hit to PF02976, DNA mismatch repair enzyme MutH, score 2e-58
550537014648	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
550537014649	HMMPfam hit to PF03741, Integral membrane protein TerC, score 4.9e-46
550537014650	7 probable transmembrane helices predicted for SEN2849 by TMHMM2.0 at aa 15-37, 50-69, 84-101, 122-139, 154-176, 183-202 and 212-230
550537014651	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
550537014652	HMMPfam hit to PF06004, Protein of unknown function DUF903, bacterial, score 7.5e-48
550537014653	1 probable transmembrane helix predicted for SEN2850 by TMHMM2.0 at aa 4-26
550537014654	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014655	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537014656	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537014657	active site
550537014658	catalytic tetrad [active]
550537014659	HMMPfam hit to PF00248, Aldo/keto reductase, score 6.5e-48
550537014660	lysophospholipid transporter LplT; Provisional; Region: PRK11195
550537014661	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537014662	12 probable transmembrane helices predicted for SEN2852 by TMHMM2.0 at aa 19-41, 51-73, 94-116, 136-158, 163-185, 195-213, 220-242, 257-279, 286-305, 309-331, 344-366 and 371-393
550537014663	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.1e-11
550537014664	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
550537014665	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
550537014666	putative acyl-acceptor binding pocket; other site
550537014667	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
550537014668	acyl-activating enzyme (AAE) consensus motif; other site
550537014669	putative AMP binding site [chemical binding]; other site
550537014670	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 9.6e-78
550537014671	PS00455  AMP-binding domain signature.
550537014672	HMMPfam hit to PF01553, Phospholipid/glycerol acyltransferase, score 2.6e-32
550537014673	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
550537014674	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537014675	DNA binding site [nucleotide binding]
550537014676	domain linker motif; other site
550537014677	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
550537014678	dimerization interface (closed form) [polypeptide binding]; other site
550537014679	ligand binding site [chemical binding]; other site
550537014680	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 4.4e-15
550537014681	PS00356 Bacterial regulatory proteins, lacI family signature.
550537014682	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 7.2e-21
550537014683	Transcriptional regulators [Transcription]; Region: PurR; COG1609
550537014684	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537014685	DNA binding site [nucleotide binding]
550537014686	domain linker motif; other site
550537014687	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
550537014688	dimerization interface (closed form) [polypeptide binding]; other site
550537014689	ligand binding site [chemical binding]; other site
550537014690	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 2.3e-11
550537014691	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 2.1e-23
550537014692	diaminopimelate decarboxylase; Provisional; Region: PRK11165
550537014693	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
550537014694	active site
550537014695	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537014696	substrate binding site [chemical binding]; other site
550537014697	catalytic residues [active]
550537014698	dimer interface [polypeptide binding]; other site
550537014699	HMMPfam hit to PF00278, Orn/DAP/Arg decarboxylase 2, score 5.4e-35
550537014700	HMMPfam hit to PF02784, Orn/DAP/Arg decarboxylase 2, score 4.2e-90
550537014701	PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2.
550537014702	PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site.
550537014703	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
550537014704	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537014705	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537014706	dimerization interface [polypeptide binding]; other site
550537014707	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 8.5e-20
550537014708	PS00044 Bacterial regulatory proteins, lysR family signature.
550537014709	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.4e-47
550537014710	putative racemase; Provisional; Region: PRK10200
550537014711	aspartate racemase; Region: asp_race; TIGR00035
550537014712	HMMPfam hit to PF01177, Asp/Glu/hydantoin racemase, score 4.9e-58
550537014713	PS00924 Aspartate and glutamate racemases signature 2.
550537014714	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014715	PS00923 Aspartate and glutamate racemases signature 1.
550537014716	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
550537014717	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537014718	putative substrate translocation pore; other site
550537014719	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537014720	HMMPfam hit to PF00083, General substrate transporter, score 1.9e-173
550537014721	12 probable transmembrane helices predicted for SEN2859 by TMHMM2.0 at aa 24-46, 61-83, 90-112, 116-138, 150-167, 177-199, 259-281, 296-318, 325-347, 362-384, 397-419 and 424-446
550537014722	PS00216 Sugar transport proteins signature 1.
550537014723	PS00217 Sugar transport proteins signature 2.
550537014724	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
550537014725	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
550537014726	NADP binding site [chemical binding]; other site
550537014727	homodimer interface [polypeptide binding]; other site
550537014728	active site
550537014729	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 1.7e-28
550537014730	PS00061 Short-chain dehydrogenases/reductases family signature.
550537014731	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
550537014732	HMMPfam hit to PF04962, 5-keto 4-deoxyuronate isomerase, score 3.6e-205
550537014733	putative acyltransferase; Provisional; Region: PRK05790
550537014734	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
550537014735	dimer interface [polypeptide binding]; other site
550537014736	active site
550537014737	HMMPfam hit to PF02803, Thiolase, score 1.4e-92
550537014738	PS00099 Thiolases active site.
550537014739	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014740	PS00737 Thiolases signature 2.
550537014741	HMMPfam hit to PF00108, Thiolase, score 2.7e-157
550537014742	PS00098 Thiolases acyl-enzyme intermediate signature.
550537014743	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537014744	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537014745	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
550537014746	dimerization interface [polypeptide binding]; other site
550537014747	HMMPfam hit to PF03466, LysR, substrate-binding, score 1e-20
550537014748	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 5.4e-16
550537014749	Predicted membrane protein [Function unknown]; Region: COG4125
550537014750	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
550537014751	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
550537014752	HMMPfam hit to PF05232, Transmembrane pair, bacterial, score 8.9e-36
550537014753	4 probable transmembrane helices predicted for SEN2864 by TMHMM2.0 at aa 24-46, 56-75, 95-117 and 121-143
550537014754	HMMPfam hit to PF05232, Transmembrane pair, bacterial, score 5e-35
550537014755	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
550537014756	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
550537014757	10 probable transmembrane helices predicted for SEN2865 by TMHMM2.0 at aa 20-42, 86-108, 123-145, 152-174, 194-216, 236-258, 287-309, 334-356, 360-382 and 389-408
550537014758	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014759	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
550537014760	putative metal binding site [ion binding]; other site
550537014761	putative homodimer interface [polypeptide binding]; other site
550537014762	putative homotetramer interface [polypeptide binding]; other site
550537014763	putative homodimer-homodimer interface [polypeptide binding]; other site
550537014764	putative allosteric switch controlling residues; other site
550537014765	HMMPfam hit to PF02583, Protein of unknown function DUF156, score 2.3e-30
550537014766	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
550537014767	6 probable transmembrane helices predicted for SEN2867 by TMHMM2.0 at aa 10-32, 53-75, 90-107, 184-206, 216-238 and 259-281
550537014768	HMMPfam hit to PF03824, Nickel/cobalt transporter, high-affinity, score 2.3e-53
550537014769	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014770	transcriptional activator SprB; Provisional; Region: PRK15320
550537014771	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
550537014772	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
550537014773	HMMPfam hit to PF07180, Protein of unknown function DUF1401, score 1.2e-118
550537014774	Fimbrial protein; Region: Fimbrial; pfam00419
550537014775	fimbrial operon std
550537014776	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
550537014777	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537014778	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537014779	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 6.6e-05
550537014780	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 5.9e-47
550537014781	PS00635 Gram-negative pili assembly chaperone signature.
550537014782	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
550537014783	PapC N-terminal domain; Region: PapC_N; pfam13954
550537014784	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537014785	PapC C-terminal domain; Region: PapC_C; pfam13953
550537014786	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 5.6e-279
550537014787	PS00017 ATP/GTP-binding site motif A (P-loop).
550537014788	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537014789	fimbrial protein StdA; Provisional; Region: PRK15210
550537014790	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 6.5e-41
550537014791	2 probable transmembrane helices predicted for SEN2873 by TMHMM2.0 at aa 15-34 and 47-65
550537014792	hypothetical protein; Provisional; Region: PRK10316
550537014793	YfdX protein; Region: YfdX; pfam10938
550537014794	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
550537014795	HMMPfam hit to PF06316, Virulence-related outer membrane protein, score 1.4e-09
550537014796	PS00695 Enterobacterial virulence outer membrane protein signature 2.
550537014797	2 probable transmembrane helices predicted for SEN2876 by TMHMM2.0 at aa 38-60 and 98-120
550537014798	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
550537014799	oligomeric interface; other site
550537014800	putative active site [active]
550537014801	homodimer interface [polypeptide binding]; other site
550537014802	HMMPfam hit to PF01850, PilT protein, N-terminal, score 1.8e-24
550537014803	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
550537014804	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
550537014805	1 probable transmembrane helix predicted for SEN2879 by TMHMM2.0 at aa 38-60
550537014806	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
550537014807	HMMPfam hit to PF07313, Protein of unknown function DUF1460, score 1.6e-152
550537014808	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
550537014809	Peptidase family M23; Region: Peptidase_M23; pfam01551
550537014810	HMMPfam hit to PF01551, Peptidase M23B, score 1.3e-52
550537014811	HMMPfam hit to PF01476, Peptidoglycan-binding LysM, score 1.1e-19
550537014812	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014813	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
550537014814	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
550537014815	active site
550537014816	metal binding site [ion binding]; metal-binding site
550537014817	nudix motif; other site
550537014818	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014819	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 1.2e-17
550537014820	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
550537014821	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
550537014822	dimer interface [polypeptide binding]; other site
550537014823	putative anticodon binding site; other site
550537014824	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
550537014825	motif 1; other site
550537014826	active site
550537014827	motif 2; other site
550537014828	motif 3; other site
550537014829	HMMPfam hit to PF00152, Aminoacyl-tRNA synthetase, class II (D, K and N), score 2.1e-133
550537014830	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537014831	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537014832	HMMPfam hit to PF01336, Nucleic acid binding, OB-fold, tRNA/helicase-type, score 1.6e-20
550537014833	This domain is found in peptide chain release factors; Region: PCRF; smart00937
550537014834	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
550537014835	RF-1 domain; Region: RF-1; pfam00472
550537014836	HMMPfam hit to PF00472, Class I peptide chain release factor, score 4.4e-74
550537014837	PS00745 Prokaryotic-type class I peptide chain release factors signature.
550537014838	HMMPfam hit to PF03462, PCRF, score 8.2e-63
550537014839	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
550537014840	DHH family; Region: DHH; pfam01368
550537014841	DHHA1 domain; Region: DHHA1; pfam02272
550537014842	HMMPfam hit to PF02272, Phosphoesterase, DHHA1, score 2.4e-17
550537014843	HMMPfam hit to PF01368, Phosphoesterase, RecJ-like, score 5.6e-53
550537014844	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
550537014845	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
550537014846	dimerization domain [polypeptide binding]; other site
550537014847	dimer interface [polypeptide binding]; other site
550537014848	catalytic residues [active]
550537014849	PS00194 Thioredoxin family active site.
550537014850	PS00190 Cytochrome c family heme-binding site signature.
550537014851	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
550537014852	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
550537014853	active site
550537014854	Int/Topo IB signature motif; other site
550537014855	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 6.7e-74
550537014856	HMMPfam hit to PF02899, Integrase, N-terminal SAM-like, phage, score 3e-31
550537014857	flavodoxin FldB; Provisional; Region: PRK12359
550537014858	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 3.4e-41
550537014859	PS00201 Flavodoxin signature.
550537014860	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
550537014861	HMMPfam hit to PF07254, Protein of unknown function DUF1434, score 6.7e-92
550537014862	1 probable transmembrane helix predicted for SEN2889 by TMHMM2.0 at aa 20-51
550537014863	hypothetical protein; Provisional; Region: PRK10878
550537014864	HMMPfam hit to PF03937, Protein of unknown function DUF339, score 5.3e-43
550537014865	putative global regulator; Reviewed; Region: PRK09559
550537014866	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
550537014867	hemolysin; Provisional; Region: PRK15087
550537014868	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
550537014869	7 probable transmembrane helices predicted for SEN2892 by TMHMM2.0 at aa 20-42, 46-68, 89-107, 112-134, 139-161, 165-187 and 194-216
550537014870	HMMPfam hit to PF03006, Hly-III related proteins, score 7.7e-65
550537014871	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
550537014872	HMMPfam hit to PF06164, Uncharacterised conserved protein UCP029143, score 2.5e-73
550537014873	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
550537014874	beta-galactosidase; Region: BGL; TIGR03356
550537014875	HMMPfam hit to PF00232, Glycoside hydrolase, family 1, score 8.1e-153
550537014876	PS00653 Glycosyl hydrolases family 1 N-terminal signature.
550537014877	PS00572 Glycosyl hydrolases family 1 active site.
550537014878	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
550537014879	glycine dehydrogenase; Provisional; Region: PRK05367
550537014880	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
550537014881	tetramer interface [polypeptide binding]; other site
550537014882	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537014883	catalytic residue [active]
550537014884	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
550537014885	tetramer interface [polypeptide binding]; other site
550537014886	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537014887	catalytic residue [active]
550537014888	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014889	HMMPfam hit to PF02347, Glycine cleavage system P-protein, score 2.3e-292
550537014890	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
550537014891	lipoyl attachment site [posttranslational modification]; other site
550537014892	HMMPfam hit to PF01597, Glycine cleavage H-protein, score 4.3e-78
550537014893	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
550537014894	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
550537014895	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
550537014896	HMMPfam hit to PF08669, Glycine cleavage T-protein, C-terminal barrel, score 4.7e-36
550537014897	HMMPfam hit to PF01571, Glycine cleavage T protein (aminomethyl transferase), score 2.2e-109
550537014898	oxidoreductase; Provisional; Region: PRK08013
550537014899	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
550537014900	HMMPfam hit to PF01494, Monooxygenase, FAD-binding, score 7.9e-12
550537014901	PS01304 ubiH/COQ6 monooxygenase family signature.
550537014902	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 3.2e-07
550537014903	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014904	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
550537014905	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
550537014906	PS01304 ubiH/COQ6 monooxygenase family signature.
550537014907	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014908	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 0.00016
550537014909	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 7.6e-05
550537014910	proline aminopeptidase P II; Provisional; Region: PRK10879
550537014911	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
550537014912	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
550537014913	active site
550537014914	HMMPfam hit to PF00557, Peptidase M24, catalytic core, score 6.4e-118
550537014915	PS00491 Aminopeptidase P and proline dipeptidase signature.
550537014916	HMMPfam hit to PF05195, Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal, score 1.2e-27
550537014917	hypothetical protein; Reviewed; Region: PRK01736
550537014918	HMMPfam hit to PF03695, Protein of unknown function UPF0149, score 5e-119
550537014919	Z-ring-associated protein; Provisional; Region: PRK10972
550537014920	HMMPfam hit to PF05164, Protein of unknown function DUF710, score 4.4e-38
550537014921	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
550537014922	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
550537014923	HMMPfam hit to PF01812, 5-formyltetrahydrofolate cyclo-ligase, score 9.5e-35
550537014924	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
550537014925	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
550537014926	ligand binding site [chemical binding]; other site
550537014927	NAD binding site [chemical binding]; other site
550537014928	tetramer interface [polypeptide binding]; other site
550537014929	catalytic site [active]
550537014930	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
550537014931	L-serine binding site [chemical binding]; other site
550537014932	ACT domain interface; other site
550537014933	HMMPfam hit to PF01842, Amino acid-binding ACT, score 1.3e-07
550537014934	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region, score 1e-35
550537014935	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding, score 2.2e-67
550537014936	PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
550537014937	PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
550537014938	PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature.
550537014939	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
550537014940	tetramer (dimer of dimers) interface [polypeptide binding]; other site
550537014941	active site
550537014942	dimer interface [polypeptide binding]; other site
550537014943	HMMPfam hit to PF06026, Ribose 5-phosphate isomerase, score 3.8e-97
550537014944	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
550537014945	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537014946	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
550537014947	putative dimerization interface [polypeptide binding]; other site
550537014948	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 4e-18
550537014949	PS00044 Bacterial regulatory proteins, lysR family signature.
550537014950	HMMPfam hit to PF03466, LysR, substrate-binding, score 4.8e-06
550537014951	Uncharacterized conserved protein [Function unknown]; Region: COG2968
550537014952	oxidative stress defense protein; Provisional; Region: PRK11087
550537014953	HMMPfam hit to PF04402, Protein of unknown function DUF541, score 1.9e-83
550537014954	arginine exporter protein; Provisional; Region: PRK09304
550537014955	HMMPfam hit to PF01810, Lysine exporter protein (LYSE/YGGA), score 3e-73
550537014956	6 probable transmembrane helices predicted for SEN2909 by TMHMM2.0 at aa 4-26, 39-61, 66-88, 111-133, 148-170 and 182-199
550537014957	mechanosensitive channel MscS; Provisional; Region: PRK10334
550537014958	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537014959	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 3.1e-83
550537014960	PS01246 Uncharacterized protein family UPF0003 signature.
550537014961	3 probable transmembrane helices predicted for SEN2910 by TMHMM2.0 at aa 26-48, 68-90 and 105-127
550537014962	HMMPfam hit to PF05552, Conserved TM helix, score 3.6e-14
550537014963	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
550537014964	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
550537014965	active site
550537014966	intersubunit interface [polypeptide binding]; other site
550537014967	zinc binding site [ion binding]; other site
550537014968	Na+ binding site [ion binding]; other site
550537014969	HMMPfam hit to PF01116, Ketose-bisphosphate aldolase, class-II, score 2.1e-211
550537014970	PS00806 Fructose-bisphosphate aldolase class-II signature 2.
550537014971	PS00602 Fructose-bisphosphate aldolase class-II signature 1.
550537014972	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
550537014973	Phosphoglycerate kinase; Region: PGK; pfam00162
550537014974	substrate binding site [chemical binding]; other site
550537014975	hinge regions; other site
550537014976	ADP binding site [chemical binding]; other site
550537014977	catalytic site [active]
550537014978	HMMPfam hit to PF00162, Phosphoglycerate kinase, score 1e-134
550537014979	PS00111 Phosphoglycerate kinase signature.
550537014980	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
550537014981	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
550537014982	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
550537014983	HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, score 1.4e-75
550537014984	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
550537014985	HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, score 4.2e-84
550537014986	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
550537014987	trimer interface [polypeptide binding]; other site
550537014988	putative Zn binding site [ion binding]; other site
550537014989	HMMPfam hit to PF03479, Protein of unknown function DUF296, score 1.9e-15
550537014990	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014991	5 probable transmembrane helices predicted for SEN2915 by TMHMM2.0 at aa 10-29, 42-64, 74-96, 103-125 and 152-174
550537014992	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
550537014993	HMMPfam hit to PF02361, Cobalt transport protein, score 0.03
550537014994	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537014995	4 probable transmembrane helices predicted for SEN2916 by TMHMM2.0 at aa 15-37, 50-72, 82-104 and 215-234
550537014996	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
550537014997	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
550537014998	Walker A/P-loop; other site
550537014999	ATP binding site [chemical binding]; other site
550537015000	Q-loop/lid; other site
550537015001	ABC transporter signature motif; other site
550537015002	Walker B; other site
550537015003	D-loop; other site
550537015004	H-loop/switch region; other site
550537015005	HMMPfam hit to PF00005, ABC transporter related, score 5.1e-23
550537015006	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015007	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
550537015008	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
550537015009	Walker A/P-loop; other site
550537015010	ATP binding site [chemical binding]; other site
550537015011	Q-loop/lid; other site
550537015012	ABC transporter signature motif; other site
550537015013	Walker B; other site
550537015014	D-loop; other site
550537015015	H-loop/switch region; other site
550537015016	HMMPfam hit to PF00005, ABC transporter related, score 5.5e-33
550537015017	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015018	transketolase; Reviewed; Region: PRK12753
550537015019	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
550537015020	TPP-binding site [chemical binding]; other site
550537015021	dimer interface [polypeptide binding]; other site
550537015022	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
550537015023	PYR/PP interface [polypeptide binding]; other site
550537015024	dimer interface [polypeptide binding]; other site
550537015025	TPP binding site [chemical binding]; other site
550537015026	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
550537015027	HMMPfam hit to PF02780, Transketolase, C-terminal, score 2e-15
550537015028	HMMPfam hit to PF02779, Transketolase, central region, score 1.6e-68
550537015029	PS00802 Transketolase signature 2.
550537015030	HMMPfam hit to PF00456, Transketolase, N-terminal, score 1.4e-257
550537015031	PS00801 Transketolase signature 1.
550537015032	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
550537015033	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015034	HMMPfam hit to PF01435, Peptidase M48, Ste24p, score 2.3e-27
550537015035	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
550537015036	agmatinase; Region: agmatinase; TIGR01230
550537015037	oligomer interface [polypeptide binding]; other site
550537015038	putative active site [active]
550537015039	Mn binding site [ion binding]; other site
550537015040	HMMPfam hit to PF00491, Ureohydrolase, score 9.9e-137
550537015041	PS01053 Arginase family signature 3.
550537015042	PS00148 Arginase family signature 2.
550537015043	PS00147 Arginase family signature 1.
550537015045	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 1e-14
550537015046	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
550537015047	HMMPfam hit to PF04074, Conserved hypothetical protein CHP00022, score 4.5e-32
550537015048	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
550537015049	HMMPfam hit to PF02615, Malate/L-lactate dehydrogenase, score 3.2e-117
550537015050	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
550537015051	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
550537015052	putative NAD(P) binding site [chemical binding]; other site
550537015053	catalytic Zn binding site [ion binding]; other site
550537015054	structural Zn binding site [ion binding]; other site
550537015055	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 1.1e-26
550537015056	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 2.5e-51
550537015057	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015058	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537015059	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
550537015060	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
550537015061	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
550537015062	HMMPfam hit to PF08125, Mannitol dehydrogenase, C-terminal, score 1.2e-89
550537015063	PS00974 Mannitol dehydrogenases signature.
550537015064	HMMPfam hit to PF01232, Mannitol dehydrogenase rossman, N-terminal, score 4.9e-64
550537015065	Transcriptional regulators [Transcription]; Region: FadR; COG2186
550537015066	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537015067	DNA-binding site [nucleotide binding]; DNA binding site
550537015068	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
550537015069	HMMPfam hit to PF07729, GntR, C-terminal, score 3.5e-34
550537015070	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 1.5e-24
550537015071	PS00043 Bacterial regulatory proteins, gntR family signature.
550537015072	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
550537015073	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015074	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
550537015075	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
550537015076	dimer interface [polypeptide binding]; other site
550537015077	active site
550537015078	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537015079	catalytic residues [active]
550537015080	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
550537015081	HMMPfam hit to PF00278, Orn/DAP/Arg decarboxylase 2, score 5.7e-41
550537015082	HMMPfam hit to PF02784, Orn/DAP/Arg decarboxylase 2, score 7.4e-120
550537015083	PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2.
550537015084	PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site.
550537015085	Virulence promoting factor; Region: YqgB; pfam11036
550537015086	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
550537015087	2 probable transmembrane helices predicted for SEN2932 by TMHMM2.0 at aa 21-43 and 63-77
550537015088	S-adenosylmethionine synthetase; Validated; Region: PRK05250
550537015089	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
550537015090	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
550537015091	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
550537015092	HMMPfam hit to PF00438, S-adenosylmethionine synthetase, score 3.7e-63
550537015093	HMMPfam hit to PF02772, S-adenosylmethionine synthetase, score 3.3e-84
550537015094	PS00376 S-adenosylmethionine synthetase signature 1.
550537015095	HMMPfam hit to PF02773, S-adenosylmethionine synthetase, score 4e-98
550537015096	PS00377 S-adenosylmethionine synthetase signature 2.
550537015097	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
550537015098	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537015099	putative substrate translocation pore; other site
550537015100	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537015101	12 probable transmembrane helices predicted for SEN2934 by TMHMM2.0 at aa 13-35, 55-77, 84-103, 108-130, 142-159, 169-191, 252-274, 289-311, 318-340, 350-372, 385-407 and 417-436
550537015102	HMMPfam hit to PF00083, General substrate transporter, score 8e-186
550537015103	PS00217 Sugar transport proteins signature 2.
550537015104	PS00216 Sugar transport proteins signature 1.
550537015105	hypothetical protein; Provisional; Region: PRK04860
550537015106	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
550537015107	HMMPfam hit to PF03926, Protein of unknown function DUF335, SprT, score 2.8e-83
550537015108	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537015109	DNA-specific endonuclease I; Provisional; Region: PRK15137
550537015110	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
550537015111	HMMPfam hit to PF04231, Endonuclease I, score 1.2e-132
550537015112	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
550537015113	RNA methyltransferase, RsmE family; Region: TIGR00046
550537015114	HMMPfam hit to PF04452, Protein of unknown function DUF558, methyltransferase predicted, score 2.9e-103
550537015115	PS00215 Mitochondrial energy transfer proteins signature.
550537015116	glutathione synthetase; Provisional; Region: PRK05246
550537015117	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
550537015118	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
550537015119	HMMPfam hit to PF02951, Prokaryotic glutathione synthetase, N-terminal, score 3.6e-73
550537015120	HMMPfam hit to PF02955, Prokaryotic glutathione synthetase, ATP-binding, score 3.9e-129
550537015121	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537015122	hypothetical protein; Validated; Region: PRK00228
550537015123	HMMPfam hit to PF02622, Protein of unknown function DUF179, score 1.1e-104
550537015124	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
550537015125	HMMPfam hit to PF03652, Resolvase, holliday junction-type, YqgF-like, score 3.1e-72
550537015126	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
550537015127	Transcriptional regulator [Transcription]; Region: IclR; COG1414
550537015128	HMMPfam hit to PF09339, Transcriptional regulator IclR, N-terminal, score 3.7e-05
550537015129	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
550537015130	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
550537015131	Walker A motif; other site
550537015132	ATP binding site [chemical binding]; other site
550537015133	Walker B motif; other site
550537015134	HMMPfam hit to PF00437, Bacterial type II secretion system protein E, score 2.2e-17
550537015135	PS00662 Bacterial type II secretion system protein E signature.
550537015136	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015137	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015138	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
550537015139	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537015140	catalytic residue [active]
550537015141	HMMPfam hit to PF01168, Alanine racemase, N-terminal, score 1.5e-31
550537015142	PS01211 Uncharacterized protein family UPF0001 signature.
550537015143	YGGT family; Region: YGGT; pfam02325
550537015144	YGGT family; Region: YGGT; pfam02325
550537015145	HMMPfam hit to PF02325, Protein of unknown function YGGT, score 3e-31
550537015146	4 probable transmembrane helices predicted for SEN2944 by TMHMM2.0 at aa 5-24, 63-85, 89-111 and 153-175
550537015147	HMMPfam hit to PF02325, Protein of unknown function YGGT, score 5.5e-31
550537015148	hypothetical protein; Validated; Region: PRK05090
550537015149	HMMPfam hit to PF02594, Protein of unknown function DUF167, score 9.4e-37
550537015150	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
550537015151	active site
550537015152	dimerization interface [polypeptide binding]; other site
550537015153	HMMPfam hit to PF01725, Ham1-like protein, score 2e-112
550537015154	HemN family oxidoreductase; Provisional; Region: PRK05660
550537015155	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537015156	FeS/SAM binding site; other site
550537015157	HemN C-terminal domain; Region: HemN_C; pfam06969
550537015158	HMMPfam hit to PF04055, Radical SAM, score 7.1e-28
550537015159	HMMPfam hit to PF06969, HemN, C-terminal, score 4.6e-21
550537015160	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
550537015161	HMMPfam hit to PF06717, Protein of unknown function DUF1202, score 1.1e-271
550537015162	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
550537015163	homodimer interface [polypeptide binding]; other site
550537015164	active site
550537015165	HMMPfam hit to PF00710, Asparaginase/glutaminase, score 9.5e-167
550537015166	PS00917 Asparaginase / glutaminase active site signature 2.
550537015167	PS00144 Asparaginase / glutaminase active site signature 1.
550537015168	1 probable transmembrane helix predicted for SEN2949 by TMHMM2.0 at aa 7-29
550537015169	hypothetical protein; Provisional; Region: PRK10626
550537015170	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
550537015171	hypothetical protein; Provisional; Region: PRK11702
550537015172	HMMPfam hit to PF04320, Protein of unknown function DUF469, score 1.9e-84
550537015173	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
550537015174	HMMPfam hit to PF02390,  methyltransferase, score 1.3e-100
550537015175	adenine DNA glycosylase; Provisional; Region: PRK10880
550537015176	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
550537015177	minor groove reading motif; other site
550537015178	helix-hairpin-helix signature motif; other site
550537015179	substrate binding pocket [chemical binding]; other site
550537015180	active site
550537015181	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
550537015182	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
550537015183	DNA binding and oxoG recognition site [nucleotide binding]
550537015184	HMMPfam hit to PF00730, HhH-GPD, score 6.9e-22
550537015185	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 1e-07
550537015186	PS01155 Endonuclease III family signature.
550537015187	PS00764 Endonuclease III iron-sulfur binding region signature.
550537015188	oxidative damage protection protein; Provisional; Region: PRK05408
550537015189	HMMPfam hit to PF04362, Fe(II) trafficking protein YggX, score 2.7e-62
550537015190	murein transglycosylase C; Provisional; Region: mltC; PRK11671
550537015191	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
550537015192	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
550537015193	N-acetyl-D-glucosamine binding site [chemical binding]; other site
550537015194	catalytic residue [active]
550537015195	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015196	HMMPfam hit to PF01464, Lytic transglycosylase-like, catalytic, score 9.7e-45
550537015197	PS00922 Prokaryotic transglycosylases signature.
550537015198	Note the frameshift mutation following codon 78
550537015199	HMMPfam hit to PF03825, Nucleoside:H+ symporter, score 1.8e-282
550537015200	2 probable transmembrane helices predicted for SEN2956 by TMHMM2.0 at aa 7-25 and 40-62
550537015201	9 probable transmembrane helices predicted for SEN2957 by TMHMM2.0 at aa 10-32, 51-68, 78-100, 127-149, 169-191, 198-217, 227-249, 262-281 and 296-318
550537015202	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015203	ornithine decarboxylase; Provisional; Region: PRK13578
550537015204	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
550537015205	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
550537015206	homodimer interface [polypeptide binding]; other site
550537015207	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537015208	catalytic residue [active]
550537015209	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
550537015210	HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal, score 2.6e-85
550537015211	HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major region, score 0
550537015212	PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site.
550537015213	HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal, score 1.3e-32
550537015214	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
550537015215	HMMPfam hit to PF04474, Protein of unknown function DUF554, score 5.4e-112
550537015216	6 probable transmembrane helices predicted for SEN2959 by TMHMM2.0 at aa 4-23, 36-58, 102-124, 145-167, 177-199 and 211-233
550537015217	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015218	Salmonella Pathogenicity Island 13; SPI-13
550537015219	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
550537015220	dimer interface [polypeptide binding]; other site
550537015221	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
550537015222	metal binding site [ion binding]; metal-binding site
550537015223	HMMPfam hit to PF00903, Glyoxalase/bleomycin resistance protein/dioxygenase, score 1e-09
550537015224	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
550537015225	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
550537015226	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
550537015227	HMMPfam hit to PF02550, Acetyl-CoA hydrolase/transferase, score 2.1e-06
550537015228	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
550537015229	putative active site [active]
550537015230	putative catalytic site [active]
550537015231	HMMPfam hit to PF01575, MaoC-like dehydratase, score 9.5e-20
550537015232	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
550537015233	HMMPfam hit to PF03328, HpcH/HpaI aldolase, score 6.9e-27
550537015234	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537015235	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
550537015236	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537015237	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
550537015238	putative dimerization interface [polypeptide binding]; other site
550537015239	putative substrate binding pocket [chemical binding]; other site
550537015240	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 9.2e-22
550537015241	HMMPfam hit to PF03466, LysR, substrate-binding, score 4.1e-49
550537015242	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
550537015243	Sulfatase; Region: Sulfatase; pfam00884
550537015244	HMMPfam hit to PF00884, Sulphatase, score 3e-53
550537015245	PS00149 Sulfatases signature 2.
550537015246	PS00523 Sulfatases signature 1.
550537015247	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
550537015248	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537015249	FeS/SAM binding site; other site
550537015250	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
550537015251	HMMPfam hit to PF04055, Radical SAM, score 7.8e-14
550537015252	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
550537015253	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537015254	DNA binding residues [nucleotide binding]
550537015255	dimerization interface [polypeptide binding]; other site
550537015256	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 2.4e-17
550537015257	PS00622 Bacterial regulatory proteins, luxR family signature.
550537015258	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
550537015259	Amino acid permease; Region: AA_permease_2; pfam13520
550537015260	HMMPfam hit to PF00324, Amino acid permease-associated region, score 0.0005
550537015261	12 probable transmembrane helices predicted for SEN2969 by TMHMM2.0 at aa 13-35, 48-70, 90-121, 136-158, 165-187, 202-224, 236-258, 293-315, 345-362, 372-394, 407-429 and 439-456
550537015262	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015263	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015264	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015265	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
550537015266	HMMPfam hit to PF05899, Protein of unknown function DUF861, cupin-3, score 2.5e-29
550537015267	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
550537015268	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
550537015269	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.4e-80
550537015270	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
550537015271	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
550537015272	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
550537015273	NAD(P) binding site [chemical binding]; other site
550537015274	catalytic residues [active]
550537015275	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 4.5e-196
550537015276	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537015277	PS00070 Aldehyde dehydrogenases cysteine active site.
550537015278	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
550537015279	HMMPfam hit to PF04965, GPW/gp25, score 0.00034
550537015280	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
550537015281	HMMPfam hit to PF05638, Virulence factor for secretion apparatus, score 3.9e-65
550537015282	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
550537015283	active site
550537015284	catalytic site [active]
550537015285	Zn binding site [ion binding]; other site
550537015286	tetramer interface [polypeptide binding]; other site
550537015287	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 1.3e-25
550537015288	Predicted amidohydrolase [General function prediction only]; Region: COG0388
550537015289	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
550537015290	putative active site [active]
550537015291	catalytic triad [active]
550537015292	putative dimer interface [polypeptide binding]; other site
550537015293	HMMPfam hit to PF00795, Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, score 1.3e-16
550537015294	PS00237 G-protein coupled receptors signature.
550537015295	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537015296	D-galactonate transporter; Region: 2A0114; TIGR00893
550537015297	putative substrate translocation pore; other site
550537015298	9 probable transmembrane helices predicted for SEN2977 by TMHMM2.0 at aa 7-29, 75-97, 137-159, 169-191, 236-258, 268-290, 311-333, 362-384 and 393-415
550537015299	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5.1e-65
550537015300	mannonate dehydratase; Provisional; Region: PRK03906
550537015301	mannonate dehydratase; Region: uxuA; TIGR00695
550537015302	HMMPfam hit to PF03786, Mannonate dehydratase, score 2.2e-292
550537015303	D-mannonate oxidoreductase; Provisional; Region: PRK15037
550537015304	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
550537015305	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
550537015306	HMMPfam hit to PF01232, Mannitol dehydrogenase rossman, N-terminal, score 8.4e-91
550537015307	HMMPfam hit to PF08125, Mannitol dehydrogenase, C-terminal, score 3.3e-127
550537015308	PS00974 Mannitol dehydrogenases signature.
550537015309	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015310	PS00215 Mitochondrial energy transfer proteins signature.
550537015311	Glucuronate isomerase; Region: UxaC; pfam02614
550537015312	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
550537015313	HMMPfam hit to PF02614, Glucuronate isomerase, score 6.2e-301
550537015314	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537015315	dimer interface [polypeptide binding]; other site
550537015316	putative CheW interface [polypeptide binding]; other site
550537015317	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
550537015318	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 4.2e-17
550537015319	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
550537015320	CHAP domain; Region: CHAP; pfam05257
550537015321	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
550537015322	HMMPfam hit to PF03738, Glutathionylspermidine synthase, score 3.7e-16
550537015323	HMMPfam hit to PF05257, Cysteine, histidine-dependent amidohydrolase/peptidase, score 1.8e-36
550537015324	1 probable transmembrane helix predicted for SEN2982 by TMHMM2.0 at aa 65-84
550537015325	putative S-transferase; Provisional; Region: PRK11752
550537015326	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
550537015327	C-terminal domain interface [polypeptide binding]; other site
550537015328	GSH binding site (G-site) [chemical binding]; other site
550537015329	dimer interface [polypeptide binding]; other site
550537015330	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
550537015331	dimer interface [polypeptide binding]; other site
550537015332	N-terminal domain interface [polypeptide binding]; other site
550537015333	active site
550537015334	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 1.9e-06
550537015335	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 3.7e-08
550537015336	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
550537015337	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
550537015338	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
550537015339	putative ligand binding residues [chemical binding]; other site
550537015340	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
550537015341	HMMPfam hit to PF01497, Periplasmic binding protein, score 1.5e-34
550537015342	hydrogenase-2 biosynthetic operon
550537015343	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
550537015344	HMMPfam hit to PF01455, Hydrogenase expression/formation protein (HUPF/HYPC), score 9.3e-41
550537015345	PS01097 Hydrogenases expression/synthesis hupF/hypC family signature.
550537015346	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
550537015347	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
550537015348	HMMPfam hit to PF01155, Hydrogenase expression/synthesis, HypA, score 4e-61
550537015349	PS01249 Hydrogenases expression/synthesis hypA family signature.
550537015350	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015351	PS00213 Lipocalin signature.
550537015352	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
550537015353	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
550537015354	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
550537015355	putative substrate-binding site; other site
550537015356	nickel binding site [ion binding]; other site
550537015357	HMMPfam hit to PF01750, Peptidase A31, hydrogen uptake protein, score 1e-48
550537015358	hydrogenase 2 large subunit; Provisional; Region: PRK10467
550537015359	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
550537015360	HMMPfam hit to PF00374, Nickel-dependent hydrogenase, large subunit, score 0
550537015361	PS00508 Nickel-dependent hydrogenases large subunit signature 2.
550537015362	PS00507 Nickel-dependent hydrogenases large subunit signature 1.
550537015363	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
550537015364	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
550537015365	10 probable transmembrane helices predicted for SEN2991 by TMHMM2.0 at aa 13-32, 52-74, 86-108, 128-150, 171-193, 208-227, 246-268, 283-302, 315-337 and 352-374
550537015366	HMMPfam hit to PF03916, Polysulphide reductase, NrfD, score 0.001
550537015367	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015368	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
550537015369	4Fe-4S binding domain; Region: Fer4_6; pfam12837
550537015370	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 3e-06
550537015371	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537015372	hydrogenase 2 small subunit; Provisional; Region: PRK10468
550537015373	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
550537015374	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
550537015375	1 probable transmembrane helix predicted for SEN2993 by TMHMM2.0 at aa 332-354
550537015376	HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 kDa subunit, score 0.00032
550537015377	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015378	HMMPfam hit to PF08425, NiFe dehydrogenase small subunit, N-terminal, score 2.1e-46
550537015379	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
550537015380	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
550537015381	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537015382	dimerization interface [polypeptide binding]; other site
550537015383	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537015384	dimer interface [polypeptide binding]; other site
550537015385	putative CheW interface [polypeptide binding]; other site
550537015386	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 4.7e-99
550537015387	PS00538 Bacterial chemotaxis sensory transducers signature.
550537015388	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 4.1e-09
550537015389	2 probable transmembrane helices predicted for SEN2995 by TMHMM2.0 at aa 10-32 and 190-212
550537015390	hypothetical protein; Provisional; Region: PRK05208
550537015391	3 probable transmembrane helices predicted for SEN2996 by TMHMM2.0 at aa 10-32, 53-75 and 136-155
550537015392	HMMPfam hit to PF03350, Protein of unknown function UPF0114, score 7.7e-55
550537015393	1 probable transmembrane helix predicted for SEN2997 by TMHMM2.0 at aa 7-29
550537015394	oxidoreductase; Provisional; Region: PRK07985
550537015395	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
550537015396	NAD binding site [chemical binding]; other site
550537015397	metal binding site [ion binding]; metal-binding site
550537015398	active site
550537015399	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 1e-18
550537015400	PS00061 Short-chain dehydrogenases/reductases family signature.
550537015401	biopolymer transport protein ExbD; Provisional; Region: PRK11267
550537015402	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
550537015403	HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 7.9e-21
550537015404	1 probable transmembrane helix predicted for SEN3001 by TMHMM2.0 at aa 20-42
550537015405	biopolymer transport protein ExbB; Provisional; Region: PRK10414
550537015406	HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel, score 5.3e-51
550537015407	3 probable transmembrane helices predicted for SEN3002 by TMHMM2.0 at aa 20-42, 131-153 and 177-199
550537015408	cystathionine beta-lyase; Provisional; Region: PRK08114
550537015409	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
550537015410	homodimer interface [polypeptide binding]; other site
550537015411	substrate-cofactor binding pocket; other site
550537015412	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537015413	catalytic residue [active]
550537015414	HMMPfam hit to PF01053, Cys/Met metabolism, pyridoxal phosphate-dependent enzyme, score 1e-172
550537015415	PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site.
550537015416	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
550537015417	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
550537015418	4 probable transmembrane helices predicted for SEN3005 by TMHMM2.0 at aa 16-38, 66-88, 158-180 and 190-212
550537015419	HMMPfam hit to PF09335, SNARE associated Golgi protein, score 4.7e-06
550537015420	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015421	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
550537015422	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
550537015423	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537015424	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537015425	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 6.2e-06
550537015426	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 4.4e-09
550537015427	HMMPfam hit to PF06719, AraC-type transcriptional regulator, N-terminal, score 1.5e-68
550537015428	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
550537015429	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
550537015430	dimer interface [polypeptide binding]; other site
550537015431	active site
550537015432	metal binding site [ion binding]; metal-binding site
550537015433	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 3.9e-14
550537015434	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537015435	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537015436	PS00060 Iron-containing alcohol dehydrogenases signature 2.
550537015437	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
550537015438	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
550537015439	active site
550537015440	catalytic tetrad [active]
550537015441	HMMPfam hit to PF00248, Aldo/keto reductase, score 2.2e-124
550537015442	PS00798 Aldo/keto reductase family signature 1.
550537015443	PS00062 Aldo/keto reductase family signature 2.
550537015444	PS00063 Aldo/keto reductase family  active site signature.
550537015445	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
550537015446	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
550537015447	transmembrane helices; other site
550537015448	HMMPfam hit to PF00939, Sodium/sulphate symporter, score 2.1e-158
550537015449	10 probable transmembrane helices predicted for SEN3009 by TMHMM2.0 at aa 7-25, 40-59, 80-97, 176-198, 228-247, 251-270, 283-305, 320-342, 349-371 and 408-430
550537015450	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
550537015451	nucleotide binding site/active site [active]
550537015452	catalytic residue [active]
550537015453	HMMPfam hit to PF01230, Histidine triad (HIT) protein, score 9.4e-09
550537015454	hypothetical protein; Provisional; Region: PRK01254
550537015455	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
550537015456	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
550537015457	HMMPfam hit to PF04055, Radical SAM, score 2.3e-12
550537015458	PS01278 Uncharacterized protein family UPF0004 signature.
550537015459	HMMPfam hit to PF08497, Radical SAM N-terminal, score 2.8e-279
550537015460	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
550537015461	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
550537015462	1 probable transmembrane helix predicted for SEN3012 by TMHMM2.0 at aa 7-26
550537015463	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015464	HMMPfam hit to PF03480, TRAP dicarboxylate transporter- DctP subunit, score 2.4e-91
550537015465	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
550537015466	4 probable transmembrane helices predicted for SEN3013 by TMHMM2.0 at aa 11-33, 48-65, 85-107 and 132-151
550537015467	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015468	HMMPfam hit to PF04290, Tripartite ATP-independent periplasmic transporter, DctQ component, score 5.4e-22
550537015469	DctM-like transporters; Region: DctM; pfam06808
550537015470	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
550537015471	11 probable transmembrane helices predicted for SEN3014 by TMHMM2.0 at aa 7-29, 62-84, 105-127, 147-169, 176-198, 229-258, 279-301, 321-338, 343-360, 370-392 and 404-426
550537015472	HMMPfam hit to PF06808, TRAP C4-dicarboxylate transport system permease DctM subunit, score 2.3e-153
550537015473	FtsI repressor; Provisional; Region: PRK10883
550537015474	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
550537015475	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
550537015476	HMMPfam hit to PF07731, Multicopper oxidase, type 2, score 3.8e-18
550537015477	HMMPfam hit to PF07732, Multicopper oxidase, type 3, score 2.7e-38
550537015478	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
550537015479	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
550537015480	putative acyl-acceptor binding pocket; other site
550537015481	HMMPfam hit to PF01553, Phospholipid/glycerol acyltransferase, score 4.6e-49
550537015482	1 probable transmembrane helix predicted for SEN3016 by TMHMM2.0 at aa 2-24
550537015483	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
550537015484	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
550537015485	CAP-like domain; other site
550537015486	active site
550537015487	primary dimer interface [polypeptide binding]; other site
550537015488	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
550537015489	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 7.7e-08
550537015490	HMMPfam hit to PF03989, DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel, score 2.7e-05
550537015491	HMMPfam hit to PF00521, DNA topoisomerase, type IIA, subunit A or C-terminal, score 6.3e-270
550537015492	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537015493	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537015494	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
550537015495	HMMPfam hit to PF06445, Bacterial transcription activator, effector binding, score 8.6e-50
550537015496	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 1.2e-05
550537015497	PS00041 Bacterial regulatory proteins, araC family signature.
550537015498	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.00093
550537015499	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
550537015500	HMMPfam hit to PF04076, Conserved hypothetical protein CHP00156, score 2e-80
550537015501	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
550537015502	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537015503	active site
550537015504	phosphorylation site [posttranslational modification]
550537015505	intermolecular recognition site; other site
550537015506	dimerization interface [polypeptide binding]; other site
550537015507	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537015508	DNA binding site [nucleotide binding]
550537015509	HMMPfam hit to PF00072, Response regulator receiver, score 2.6e-30
550537015510	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 3.7e-24
550537015511	sensor protein QseC; Provisional; Region: PRK10337
550537015512	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
550537015513	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537015514	dimer interface [polypeptide binding]; other site
550537015515	phosphorylation site [posttranslational modification]
550537015516	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537015517	ATP binding site [chemical binding]; other site
550537015518	Mg2+ binding site [ion binding]; other site
550537015519	G-X-G motif; other site
550537015520	2 probable transmembrane helices predicted for SEN3021 by TMHMM2.0 at aa 13-32 and 159-181
550537015521	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 3.8e-07
550537015522	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 3.2e-14
550537015523	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.8e-29
550537015524	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
550537015525	HMMPfam hit to PF02525, Flavodoxin-like fold, score 1.4e-75
550537015526	Uncharacterized conserved protein [Function unknown]; Region: COG1359
550537015527	HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 1.8e-13
550537015528	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
550537015529	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
550537015530	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537015531	ATP binding site [chemical binding]; other site
550537015532	Mg2+ binding site [ion binding]; other site
550537015533	G-X-G motif; other site
550537015534	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
550537015535	anchoring element; other site
550537015536	dimer interface [polypeptide binding]; other site
550537015537	ATP binding site [chemical binding]; other site
550537015538	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
550537015539	active site
550537015540	metal binding site [ion binding]; metal-binding site
550537015541	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
550537015542	HMMPfam hit to PF00986, DNA topoisomerase, type IIA, subunit B, C-terminal, score 1.1e-32
550537015543	PS00177 DNA topoisomerase II signature.
550537015544	HMMPfam hit to PF00204, DNA topoisomerase, type IIA, subunit B, region 2, score 1.9e-58
550537015545	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 9.4e-26
550537015546	esterase YqiA; Provisional; Region: PRK11071
550537015547	HMMPfam hit to PF05728, Protein of unknown function UPF0227, score 5.9e-109
550537015548	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
550537015549	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
550537015550	active site
550537015551	metal binding site [ion binding]; metal-binding site
550537015552	hexamer interface [polypeptide binding]; other site
550537015553	HMMPfam hit to PF08413, Calcineurin-like phosphoesterase C-terminal, score 3.3e-43
550537015554	HMMPfam hit to PF00149, Metallophosphoesterase, score 7.7e-21
550537015555	putative dehydrogenase; Provisional; Region: PRK11039
550537015556	HMMPfam hit to PF06853, Protein of unknown function DUF1249, score 6.3e-95
550537015557	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
550537015558	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
550537015559	dimer interface [polypeptide binding]; other site
550537015560	ADP-ribose binding site [chemical binding]; other site
550537015561	active site
550537015562	nudix motif; other site
550537015563	metal binding site [ion binding]; metal-binding site
550537015564	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 2e-23
550537015565	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
550537015566	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.8e-44
550537015567	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.3e-53
550537015568	hypothetical protein; Provisional; Region: PRK11653
550537015569	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015570	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
550537015571	HMMPfam hit to PF03738, Glutathionylspermidine synthase, score 1.2e-265
550537015572	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
550537015573	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
550537015574	putative active site [active]
550537015575	metal binding site [ion binding]; metal-binding site
550537015576	HMMPfam hit to PF02900, Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B, score 6.3e-98
550537015577	zinc transporter ZupT; Provisional; Region: PRK04201
550537015578	ZIP Zinc transporter; Region: Zip; pfam02535
550537015579	8 probable transmembrane helices predicted for SEN3033 by TMHMM2.0 at aa 5-24, 31-50, 65-87, 108-130, 140-162, 169-191, 195-217 and 234-256
550537015580	HMMPfam hit to PF02535, Zinc/iron permease, score 1.7e-51
550537015581	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
550537015582	1 probable transmembrane helix predicted for SEN3034 by TMHMM2.0 at aa 9-31
550537015583	HMMPfam hit to PF05935, Arylsulphotransferase, score 0
550537015584	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
550537015585	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
550537015586	catalytic residues [active]
550537015587	hinge region; other site
550537015588	alpha helical domain; other site
550537015589	HMMPfam hit to PF01323, DSBA oxidoreductase, score 1.4e-05
550537015590	putative disulfide oxidoreductase; Provisional; Region: PRK04307
550537015591	4 probable transmembrane helices predicted for SEN3036 by TMHMM2.0 at aa 27-49, 59-78, 83-105 and 197-219
550537015592	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015593	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
550537015594	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
550537015595	HMMPfam hit to PF00926, 3,4-Dihydroxy-2-butanone 4-phosphate synthase, score 1.6e-128
550537015596	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
550537015597	HMMPfam hit to PF04380, Protein of unknown function DUF526, score 9.3e-48
550537015598	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
550537015599	HMMPfam hit to PF08971, Glycogen synthesis protein, score 7.2e-55
550537015600	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
550537015601	HMMPfam hit to PF07290, Protein of unknown function DUF1449, score 3.1e-149
550537015602	3 probable transmembrane helices predicted for SEN3040 by TMHMM2.0 at aa 13-35, 63-85 and 98-117
550537015603	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
550537015604	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
550537015605	2 probable transmembrane helices predicted for SEN3041 by TMHMM2.0 at aa 11-33 and 46-68
550537015606	HMMPfam hit to PF01145, Band 7 protein, score 1.9e-40
550537015607	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
550537015608	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
550537015609	putative ribose interaction site [chemical binding]; other site
550537015610	putative ADP binding site [chemical binding]; other site
550537015611	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
550537015612	active site
550537015613	nucleotide binding site [chemical binding]; other site
550537015614	HIGH motif; other site
550537015615	KMSKS motif; other site
550537015616	HMMPfam hit to PF01467, Cytidylyltransferase, score 5.7e-24
550537015617	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 1.3e-61
550537015618	PS00583 pfkB family of carbohydrate kinases signature 1.
550537015619	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
550537015620	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
550537015621	metal binding triad; other site
550537015622	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
550537015623	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
550537015624	metal binding triad; other site
550537015625	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
550537015626	HMMPfam hit to PF03710, Glutamate-ammonia ligase adenylyltransferase, score 4.1e-151
550537015627	PS00904 Protein prenyltransferases alpha subunit repeat signature.
550537015628	HMMPfam hit to PF03710, Glutamate-ammonia ligase adenylyltransferase, score 1.8e-124
550537015629	Uncharacterized conserved protein [Function unknown]; Region: COG3025
550537015630	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
550537015631	putative active site [active]
550537015632	putative metal binding residues [ion binding]; other site
550537015633	signature motif; other site
550537015634	putative triphosphate binding site [ion binding]; other site
550537015635	CHAD domain; Region: CHAD; pfam05235
550537015636	HMMPfam hit to PF05235, CHAD, score 1.3e-36
550537015637	HMMPfam hit to PF01928, Adenylate cyclase, score 3.4e-69
550537015638	SH3 domain-containing protein; Provisional; Region: PRK10884
550537015639	Bacterial SH3 domain homologues; Region: SH3b; smart00287
550537015640	HMMPfam hit to PF08239, SH3, type 3, score 0.0022
550537015641	1 probable transmembrane helix predicted for SEN3045 by TMHMM2.0 at aa 167-189
550537015642	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
550537015643	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
550537015644	active site
550537015645	NTP binding site [chemical binding]; other site
550537015646	metal binding triad [ion binding]; metal-binding site
550537015647	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
550537015648	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
550537015649	Zn2+ binding site [ion binding]; other site
550537015650	Mg2+ binding site [ion binding]; other site
550537015651	HMMPfam hit to PF01743, Polynucleotide adenylyltransferase region, score 6.3e-51
550537015652	HMMPfam hit to PF01966, Metal-dependent phosphohydrolase, HD region, subdomain, score 8.4e-19
550537015653	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
550537015654	7 probable transmembrane helices predicted for SEN3047 by TMHMM2.0 at aa 7-29, 49-71, 91-110, 120-137, 188-210, 225-247 and 254-273
550537015655	HMMPfam hit to PF02673, Bacitracin resistance protein BacA, score 3.4e-154
550537015656	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
550537015657	homooctamer interface [polypeptide binding]; other site
550537015658	active site
550537015659	HMMPfam hit to PF02152, Dihydroneopterin aldolase, score 5.8e-52
550537015660	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
550537015661	5 probable transmembrane helices predicted for SEN3049 by TMHMM2.0 at aa 4-26, 53-75, 80-102, 109-131 and 136-158
550537015662	HMMPfam hit to PF02660, Protein of unknown function DUF205, score 9.4e-108
550537015663	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015664	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015665	HMMPfam hit to PF05681, Fe-S type hydro-lyases tartrate/fumarate alpha region, score 1.6e-13
550537015666	UGMP family protein; Validated; Region: PRK09604
550537015667	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
550537015668	HMMPfam hit to PF00814, Peptidase M22, glycoprotease, score 3.4e-76; PS01016 Glycoprotease family signature.
550537015669	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
550537015670	HMMPfam hit to PF01165, Ribosomal protein S21, score 2.7e-35
550537015671	PS01181 Ribosomal protein S21 signature.
550537015672	DNA primase; Validated; Region: dnaG; PRK05667
550537015673	CHC2 zinc finger; Region: zf-CHC2; pfam01807
550537015674	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
550537015675	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
550537015676	active site
550537015677	metal binding site [ion binding]; metal-binding site
550537015678	interdomain interaction site; other site
550537015679	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
550537015680	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
550537015681	HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 3.5e-67
550537015682	HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 2.5e-66
550537015683	PS00136 Serine proteases, subtilase family, aspartic acid active site.
550537015684	HMMPfam hit to PF01751, TOPRIM, score 1.3e-24
550537015685	HMMPfam hit to PF08278, DNA primase DnaG, DnaB-binding, score 1.2e-57
550537015686	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
550537015687	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
550537015688	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
550537015689	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
550537015690	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
550537015691	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
550537015692	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
550537015693	DNA binding residues [nucleotide binding]
550537015694	HMMPfam hit to PF03979, RNA polymerase sigma factor 70, region 1.1, score 3.5e-43
550537015695	HMMPfam hit to PF00140, RNA polymerase sigma-70 region 1.2, score 2.7e-15
550537015696	HMMPfam hit to PF04546, RNA polymerase sigma factor 70, non-essential region, score 9.3e-125
550537015697	HMMPfam hit to PF04542, RNA polymerase sigma-70 region 2, score 2e-28
550537015698	PS00715 Sigma-70 factors family signature 1.
550537015699	HMMPfam hit to PF04539, RNA polymerase sigma-70 region 3, score 2.3e-41
550537015700	HMMPfam hit to PF04545, RNA polymerase sigma-70 region 4, score 1.1e-24
550537015701	PS00716 Sigma-70 factors family signature 2.
550537015702	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
550537015703	active site
550537015704	SUMO-1 interface [polypeptide binding]; other site
550537015705	HMMPfam hit to PF03167, Uracil-DNA glycosylase superfamily, score 6.1e-25
550537015706	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
550537015707	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
550537015708	FAD binding pocket [chemical binding]; other site
550537015709	FAD binding motif [chemical binding]; other site
550537015710	phosphate binding motif [ion binding]; other site
550537015711	NAD binding pocket [chemical binding]; other site
550537015712	HMMPfam hit to PF04954, Siderophore-interacting protein, score 2.9e-40
550537015713	HMMPfam hit to PF08021, FAD-binding 9, siderophore-interacting, score 3.7e-52
550537015714	Predicted transcriptional regulators [Transcription]; Region: COG1695
550537015715	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
550537015716	HMMPfam hit to PF03551, Transcriptional regulator PadR-like, score 1e-18
550537015717	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
550537015718	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537015719	dimerization interface [polypeptide binding]; other site
550537015720	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
550537015721	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537015722	dimer interface [polypeptide binding]; other site
550537015723	putative CheW interface [polypeptide binding]; other site
550537015724	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 5.2e-74
550537015725	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 2.8e-13
550537015726	2 probable transmembrane helices predicted for SEN3058 by TMHMM2.0 at aa 12-34 and 192-211
550537015727	PAS fold; Region: PAS_3; pfam08447
550537015728	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537015729	putative active site [active]
550537015730	heme pocket [chemical binding]; other site
550537015731	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
550537015732	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
550537015733	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537015734	dimer interface [polypeptide binding]; other site
550537015735	putative CheW interface [polypeptide binding]; other site
550537015736	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 2.8e-60
550537015737	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 3.2e-05
550537015738	HMMPfam hit to PF08447, PAS fold-3, score 2.4e-16
550537015739	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
550537015740	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
550537015741	inhibitor-cofactor binding pocket; inhibition site
550537015742	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537015743	catalytic residue [active]
550537015744	HMMPfam hit to PF00202, Aminotransferase class-III, score 1.5e-180
550537015745	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
550537015746	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
550537015747	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
550537015748	active site
550537015749	FMN binding site [chemical binding]; other site
550537015750	2,4-decadienoyl-CoA binding site; other site
550537015751	catalytic residue [active]
550537015752	4Fe-4S cluster binding site [ion binding]; other site
550537015753	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
550537015754	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537015755	HMMPfam hit to PF00724, NADH:flavin oxidoreductase/NADH oxidase, N-terminal, score 3.7e-145
550537015756	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 2.7e-08
550537015757	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
550537015758	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537015759	S-adenosylmethionine binding site [chemical binding]; other site
550537015760	HMMPfam hit to PF05175, Methyltransferase small, score 7.2e-82
550537015761	PS00092 N-6 Adenine-specific DNA methylases signature.
550537015762	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
550537015763	HMMPfam hit to PF01863, Protein of unknown function DUF45, score 5.2e-05
550537015764	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
550537015765	putative active site [active]
550537015766	1 probable transmembrane helix predicted for SEN3064 by TMHMM2.0 at aa 19-41
550537015767	HMMPfam hit to PF02698, Protein of unknown function DUF218, score 4.8e-44
550537015768	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
550537015769	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
550537015770	HMMPfam hit to PF01408, Oxidoreductase, N-terminal, score 7.3e-42
550537015771	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
550537015772	9 probable transmembrane helices predicted for SEN3066 by TMHMM2.0 at aa 10-29, 42-64, 79-101, 114-136, 142-161, 198-220, 235-257, 264-286 and 290-312
550537015773	HMMPfam hit to PF03741, Integral membrane protein TerC, score 1.1e-61
550537015774	serine/threonine transporter SstT; Provisional; Region: PRK13628
550537015775	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
550537015776	8 probable transmembrane helices predicted for SEN3067 by TMHMM2.0 at aa 13-35, 50-72, 84-106, 141-163, 191-213, 218-240, 292-314 and 329-351
550537015777	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter, score 7.5e-173
550537015778	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015779	PS00435 Peroxidases proximal heme-ligand signature.
550537015780	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015781	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
550537015782	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
550537015783	6 probable transmembrane helices predicted for SEN3068 by TMHMM2.0 at aa 20-38, 40-62, 66-88, 123-145, 155-177 and 190-212
550537015784	HMMPfam hit to PF09335, SNARE associated Golgi protein, score 8.1e-08
550537015785	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015786	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
550537015787	1 probable transmembrane helix predicted for SEN3069 by TMHMM2.0 at aa 12-31
550537015788	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
550537015789	HMMPfam hit to PF06476, Protein of unknown function DUF1090, score 2.2e-53
550537015790	Predicted membrane protein [Function unknown]; Region: COG5393
550537015791	2 probable transmembrane helices predicted for SEN3071 by TMHMM2.0 at aa 50-72 and 82-104
550537015792	YqjK-like protein; Region: YqjK; pfam13997
550537015793	Predicted membrane protein [Function unknown]; Region: COG2259
550537015794	HMMPfam hit to PF07681, DoxX, score 5.3e-27
550537015795	4 probable transmembrane helices predicted for SEN3073 by TMHMM2.0 at aa 40-62, 77-99, 104-121 and 136-153
550537015796	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
550537015797	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
550537015798	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
550537015799	putative dimer interface [polypeptide binding]; other site
550537015800	N-terminal domain interface [polypeptide binding]; other site
550537015801	putative substrate binding pocket (H-site) [chemical binding]; other site
550537015802	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 8.4e-05
550537015803	Predicted membrane protein [Function unknown]; Region: COG3152
550537015804	HMMPfam hit to PF05656, Protein of unknown function DUF805, score 1.6e-45
550537015805	3 probable transmembrane helices predicted for SEN3075 by TMHMM2.0 at aa 24-46, 51-70 and 82-101
550537015806	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537015807	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
550537015808	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537015809	dimerization interface [polypeptide binding]; other site
550537015810	HMMPfam hit to PF03466, LysR, substrate-binding, score 4e-15
550537015811	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 3.2e-15
550537015812	PS00044 Bacterial regulatory proteins, lysR family signature.
550537015813	Pirin-related protein [General function prediction only]; Region: COG1741
550537015814	Pirin; Region: Pirin; pfam02678
550537015815	HMMPfam hit to PF02678, Pirin, N-terminal, score 4.5e-41
550537015816	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
550537015817	HMMPfam hit to PF06354, Protein of unknown function DUF1063, score 2e-258
550537015818	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
550537015819	serine transporter; Region: stp; TIGR00814
550537015820	11 probable transmembrane helices predicted for SEN3080 by TMHMM2.0 at aa 38-60, 65-87, 112-134, 149-171, 184-206, 221-243, 264-286, 318-340, 363-385, 389-411 and 423-442
550537015821	L-serine dehydratase TdcG; Provisional; Region: PRK15040
550537015822	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
550537015823	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
550537015824	HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 4.3e-193
550537015825	HMMPfam hit to PF03315, Serine dehydratase beta chain, score 2.2e-91
550537015826	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
550537015827	Pyruvate formate lyase 1; Region: PFL1; cd01678
550537015828	coenzyme A binding site [chemical binding]; other site
550537015829	active site
550537015830	catalytic residues [active]
550537015831	glycine loop; other site
550537015832	HMMPfam hit to PF01228, Formate C-acetyltransferase glycine radical, score 7.2e-60
550537015833	PS00850 Glycine radical signature.
550537015834	HMMPfam hit to PF02901, Pyruvate formate-lyase, PFL, score 0
550537015835	propionate/acetate kinase; Provisional; Region: PRK12379
550537015836	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
550537015837	HMMPfam hit to PF00871, Acetate and butyrate kinase, score 9.5e-225
550537015838	PS01076 Acetate and butyrate kinases family signature 2.
550537015839	PS01075 Acetate and butyrate kinases family signature 1.
550537015840	threonine/serine transporter TdcC; Provisional; Region: PRK13629
550537015841	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
550537015842	11 probable transmembrane helices predicted for SEN3084 by TMHMM2.0 at aa 23-40, 44-66, 97-119, 134-156, 163-185, 212-234, 255-277, 315-337, 358-380, 390-409 and 422-440
550537015843	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015844	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
550537015845	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
550537015846	tetramer interface [polypeptide binding]; other site
550537015847	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537015848	catalytic residue [active]
550537015849	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 1.8e-97
550537015850	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015851	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
550537015852	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
550537015853	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537015854	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
550537015855	putative substrate binding pocket [chemical binding]; other site
550537015856	putative dimerization interface [polypeptide binding]; other site
550537015857	HMMPfam hit to PF03466, LysR, substrate-binding, score 2e-29
550537015858	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 5.1e-21
550537015859	PS00044 Bacterial regulatory proteins, lysR family signature.
550537015860	glycerate kinase I; Provisional; Region: PRK10342
550537015861	HMMPfam hit to PF02595, Glycerate kinase, score 6.6e-266
550537015862	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015863	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
550537015864	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
550537015865	HMMPfam hit to PF03446, 6-phosphogluconate dehydrogenase, NAD-binding, score 2.5e-81
550537015866	PS00895 3-hydroxyisobutyrate dehydrogenase signature.
550537015867	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
550537015868	HMMPfam hit to PF03328, HpcH/HpaI aldolase, score 3.2e-101
550537015869	galactarate dehydratase; Region: galactar-dH20; TIGR03248
550537015870	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
550537015871	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
550537015872	HMMPfam hit to PF08666, SAF domain, score 1.7e-12
550537015873	HMMPfam hit to PF04295, D-galactarate dehydratase/Altronate hydrolase, C-terminal, score 9.9e-249
550537015874	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
550537015875	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
550537015876	intersubunit interface [polypeptide binding]; other site
550537015877	active site
550537015878	zinc binding site [ion binding]; other site
550537015879	Na+ binding site [ion binding]; other site
550537015880	HMMPfam hit to PF01116, Ketose-bisphosphate aldolase, class-II, score 1.3e-141
550537015881	PS00806 Fructose-bisphosphate aldolase class-II signature 2.
550537015882	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
550537015883	HMMPfam hit to PF08013, D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit AgaZ, score 0
550537015884	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537015885	active site
550537015886	phosphorylation site [posttranslational modification]
550537015887	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 8.5e-07
550537015888	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
550537015889	active site
550537015890	P-loop; other site
550537015891	phosphorylation site [posttranslational modification]
550537015892	HMMPfam hit to PF02302, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, score 1.2e-16
550537015893	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
550537015894	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
550537015895	9 probable transmembrane helices predicted for SEN3095 by TMHMM2.0 at aa 4-26, 39-61, 91-113, 134-156, 225-247, 299-321, 331-348, 353-375 and 411-433
550537015896	PS00962 Ribosomal protein S2 signature 1.
550537015897	HMMPfam hit to PF03611, Phosphotransferase system, galactitol-specific IIC component, score 1.7e-185
550537015898	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
550537015899	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
550537015900	putative NAD(P) binding site [chemical binding]; other site
550537015901	catalytic Zn binding site [ion binding]; other site
550537015902	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 1.3e-40
550537015903	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537015904	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015905	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 1.4e-37
550537015906	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537015907	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537015908	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537015909	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 2.4e-18
550537015910	PS00894 Bacterial regulatory proteins, deoR family signature.
550537015911	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 4.5e-53
550537015912	PS00141 Eukaryotic and viral aspartyl proteases active site.
550537015913	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
550537015914	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
550537015915	putative SAM binding site [chemical binding]; other site
550537015916	putative homodimer interface [polypeptide binding]; other site
550537015917	HMMPfam hit to PF00590, Tetrapyrrole methylase, score 6.1e-72
550537015918	PS01296 Uncharacterized protein family UPF0011 signature.
550537015919	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
550537015920	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
550537015921	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
550537015922	putative ligand binding site [chemical binding]; other site
550537015923	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015924	HMMPfam hit to PF04348, LppC  lipoprotein, score 1e-106
550537015925	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015926	TIGR00252 family protein; Region: TIGR00252
550537015927	HMMPfam hit to PF02021, Protein of unknown function UPF0102, score 4.8e-56
550537015928	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
550537015929	dimer interface [polypeptide binding]; other site
550537015930	active site
550537015931	outer membrane lipoprotein; Provisional; Region: PRK11023
550537015932	BON domain; Region: BON; pfam04972
550537015933	BON domain; Region: BON; pfam04972
550537015934	1 probable transmembrane helix predicted for SEN3102 by TMHMM2.0 at aa 7-29
550537015935	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537015936	HMMPfam hit to PF04972, Transport-associated, score 2.4e-09
550537015937	HMMPfam hit to PF04972, Transport-associated, score 1.6e-11
550537015938	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
550537015939	NADH(P)-binding; Region: NAD_binding_10; pfam13460
550537015940	NAD binding site [chemical binding]; other site
550537015941	active site
550537015942	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD - binding, score 7.1e-07
550537015943	intracellular protease, PfpI family; Region: PfpI; TIGR01382
550537015944	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
550537015945	proposed catalytic triad [active]
550537015946	conserved cys residue [active]
550537015947	HMMPfam hit to PF01965, ThiJ/PfpI, score 4.8e-57
550537015948	hypothetical protein; Provisional; Region: PRK03467
550537015949	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
550537015950	GIY-YIG motif/motif A; other site
550537015951	putative active site [active]
550537015952	putative metal binding site [ion binding]; other site
550537015953	HMMPfam hit to PF01541, Excinuclease ABC, C subunit, N-terminal, score 7.2e-16
550537015954	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
550537015955	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537015956	Coenzyme A binding pocket [chemical binding]; other site
550537015957	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 4.7e-15
550537015958	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
550537015959	HMMPfam hit to PF02036, Sterol-binding, score 1.7e-27
550537015960	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
550537015961	Peptidase family U32; Region: Peptidase_U32; pfam01136
550537015962	HMMPfam hit to PF01136, Peptidase U32, score 1.3e-124
550537015963	PS01276 Peptidase family U32 signature.
550537015964	putative protease; Provisional; Region: PRK15447
550537015965	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
550537015966	HMMPfam hit to PF01136, Peptidase U32, score 1.5e-07
550537015967	hypothetical protein; Provisional; Region: PRK10508
550537015968	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
550537015969	HMMPfam hit to PF00296, Bacterial luciferase-like, score 1.5e-14
550537015970	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
550537015971	HMMPfam hit to PF06104, Protein of unknown function DUF949, bacterial, score 7.2e-152
550537015972	1 probable transmembrane helix predicted for SEN3112 by TMHMM2.0 at aa 5-27
550537015973	tryptophan permease; Provisional; Region: PRK10483
550537015974	aromatic amino acid transport protein; Region: araaP; TIGR00837
550537015975	10 probable transmembrane helices predicted for SEN3114 by TMHMM2.0 at aa 10-32, 59-81, 96-118, 125-147, 162-184, 197-219, 256-278, 290-312, 317-339 and 360-382
550537015976	HMMPfam hit to PF03222, Aromatic amino acid permease, score 5.3e-221
550537015977	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
550537015978	DEAD-like helicases superfamily; Region: DEXDc; smart00487
550537015979	ATP binding site [chemical binding]; other site
550537015980	Mg++ binding site [ion binding]; other site
550537015981	motif III; other site
550537015982	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537015983	nucleotide binding region [chemical binding]; other site
550537015984	ATP-binding site [chemical binding]; other site
550537015985	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
550537015986	putative RNA binding site [nucleotide binding]; other site
550537015987	HMMPfam hit to PF03880, DbpA, RNA-binding, score 2.8e-42
550537015988	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 2.7e-34
550537015989	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 8.6e-76
550537015990	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
550537015991	PS00017 ATP/GTP-binding site motif A (P-loop).
550537015992	lipoprotein NlpI; Provisional; Region: PRK11189
550537015993	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
550537015994	binding surface
550537015995	TPR motif; other site
550537015996	HMMPfam hit to PF00515, Tetratricopeptide TPR-1, score 0.22
550537015997	HMMPfam hit to PF00515, Tetratricopeptide TPR-1, score 1.2e-06
550537015998	HMMPfam hit to PF00515, Tetratricopeptide TPR-1, score 0.00013
550537015999	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016000	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
550537016001	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
550537016002	RNase E interface [polypeptide binding]; other site
550537016003	trimer interface [polypeptide binding]; other site
550537016004	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
550537016005	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
550537016006	RNase E interface [polypeptide binding]; other site
550537016007	trimer interface [polypeptide binding]; other site
550537016008	active site
550537016009	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
550537016010	putative nucleic acid binding region [nucleotide binding]; other site
550537016011	G-X-X-G motif; other site
550537016012	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
550537016013	RNA binding site [nucleotide binding]; other site
550537016014	domain interface; other site
550537016015	HMMPfam hit to PF00575, S1, RNA binding, score 3.2e-27
550537016016	HMMPfam hit to PF00013, K Homology, type 1, score 1.4e-15
550537016017	HMMPfam hit to PF03725, Exoribonuclease, phosphorolytic domain 2, score 9.7e-22
550537016018	HMMPfam hit to PF01138, Exoribonuclease, phosphorolytic domain 1, score 1e-54
550537016019	HMMPfam hit to PF03726, Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type, score 1.6e-38
550537016020	HMMPfam hit to PF03725, Exoribonuclease, phosphorolytic domain 2, score 6e-19
550537016021	HMMPfam hit to PF01138, Exoribonuclease, phosphorolytic domain 1, score 9.2e-44
550537016022	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
550537016023	16S/18S rRNA binding site [nucleotide binding]; other site
550537016024	S13e-L30e interaction site [polypeptide binding]; other site
550537016025	25S rRNA binding site [nucleotide binding]; other site
550537016026	HMMPfam hit to PF00312, Ribosomal protein S15, score 2.8e-48
550537016027	PS00362 Ribosomal protein S15 signature.
550537016028	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
550537016029	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
550537016030	RNA binding site [nucleotide binding]; other site
550537016031	active site
550537016032	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
550537016033	HMMPfam hit to PF09157, tRNA pseudouridine synthase B, C-terminal, score 7.8e-28
550537016034	HMMPfam hit to PF01509, tRNA pseudouridine synthase B, N-terminal, score 2.4e-93
550537016035	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
550537016036	HMMPfam hit to PF02033, Ribosome-binding factor A, score 1e-64
550537016037	PS01319 Ribosome-binding factor A signature.
550537016038	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
550537016039	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
550537016040	translation initiation factor IF-2; Region: IF-2; TIGR00487
550537016041	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
550537016042	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
550537016043	G1 box; other site
550537016044	putative GEF interaction site [polypeptide binding]; other site
550537016045	GTP/Mg2+ binding site [chemical binding]; other site
550537016046	Switch I region; other site
550537016047	G2 box; other site
550537016048	G3 box; other site
550537016049	Switch II region; other site
550537016050	G4 box; other site
550537016051	G5 box; other site
550537016052	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
550537016053	Translation-initiation factor 2; Region: IF-2; pfam11987
550537016054	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
550537016055	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 6.5e-11
550537016056	PS01176 Initiation factor 2 signature.
550537016057	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 1.2e-13
550537016058	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 1.9e-56
550537016059	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016060	HMMPfam hit to PF04760, Translation initiation factor IF-2, N-terminal, score 3.6e-21
550537016061	HMMPfam hit to PF08364, Initiation factor 2 associated region, bacterial, score 3.5e-22
550537016062	HMMPfam hit to PF04760, Translation initiation factor IF-2, N-terminal, score 4.3e-08
550537016063	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
550537016064	NusA N-terminal domain; Region: NusA_N; pfam08529
550537016065	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
550537016066	RNA binding site [nucleotide binding]; other site
550537016067	homodimer interface [polypeptide binding]; other site
550537016068	NusA-like KH domain; Region: KH_5; pfam13184
550537016069	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
550537016070	G-X-X-G motif; other site
550537016071	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
550537016072	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
550537016073	HMMPfam hit to PF00575, S1, RNA binding, score 2.4e-07
550537016074	HMMPfam hit to PF08529, Transcription factor NusA, N-terminal, score 2.4e-67
550537016075	ribosome maturation protein RimP; Reviewed; Region: PRK00092
550537016076	hypothetical protein; Provisional; Region: PRK14641
550537016077	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
550537016078	putative oligomer interface [polypeptide binding]; other site
550537016079	putative RNA binding site [nucleotide binding]; other site
550537016080	HMMPfam hit to PF02576, Protein of unknown function DUF150, score 3e-72
550537016081	argininosuccinate synthase; Validated; Region: PRK05370
550537016082	argininosuccinate synthase; Provisional; Region: PRK13820
550537016083	HMMPfam hit to PF00764, Argininosuccinate synthase, score 8.4e-218
550537016084	PS00564 Argininosuccinate synthase signature 1.
550537016085	PS00565 Argininosuccinate synthase signature 2.
550537016086	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537016087	non-specific DNA binding site [nucleotide binding]; other site
550537016088	salt bridge; other site
550537016089	sequence-specific DNA binding site [nucleotide binding]; other site
550537016090	Preprotein translocase SecG subunit; Region: SecG; pfam03840
550537016091	HMMPfam hit to PF03840, Preprotein translocase SecG subunit, score 1.3e-35
550537016092	2 probable transmembrane helices predicted for SEN3126 by TMHMM2.0 at aa 5-22 and 51-73
550537016093	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
550537016094	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
550537016095	active site
550537016096	substrate binding site [chemical binding]; other site
550537016097	metal binding site [ion binding]; metal-binding site
550537016098	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase C-terminal, score 4.1e-20
550537016099	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III, score 2.2e-41
550537016100	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II, score 1.1e-46
550537016101	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, score 1.9e-62
550537016102	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
550537016103	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
550537016104	dihydropteroate synthase; Region: DHPS; TIGR01496
550537016105	substrate binding pocket [chemical binding]; other site
550537016106	dimer interface [polypeptide binding]; other site
550537016107	inhibitor binding site; inhibition site
550537016108	HMMPfam hit to PF00809, Dihydropteroate synthase, DHPS, score 9.6e-106
550537016109	PS00793 Dihydropteroate synthase signature 2.
550537016110	PS00792 Dihydropteroate synthase signature 1.
550537016111	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
550537016112	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537016113	Walker A motif; other site
550537016114	ATP binding site [chemical binding]; other site
550537016115	Walker B motif; other site
550537016116	arginine finger; other site
550537016117	Peptidase family M41; Region: Peptidase_M41; pfam01434
550537016118	HMMPfam hit to PF01434, Peptidase M41, score 1.7e-129
550537016119	HMMPfam hit to PF00004, AAA ATPase, core, score 6e-102
550537016120	PS00674 AAA-protein family signature.
550537016121	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016122	HMMPfam hit to PF06480, Peptidase M41, FtsH extracellular, score 3.1e-50
550537016123	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016124	2 probable transmembrane helices predicted for SEN3129 by TMHMM2.0 at aa 5-24 and 97-119
550537016125	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
550537016126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537016127	S-adenosylmethionine binding site [chemical binding]; other site
550537016128	HMMPfam hit to PF01728, Ribosomal RNA methyltransferase RrmJ/FtsJ, score 2.3e-77
550537016129	RNA-binding protein YhbY; Provisional; Region: PRK10343
550537016130	HMMPfam hit to PF01985, CRS1/YhbY, score 2.9e-38
550537016131	PS01301 Uncharacterized protein family UPF0044 signature.
550537016132	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
550537016133	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
550537016134	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
550537016135	HMMPfam hit to PF01272, Transcription elongation factor, GreA/GreB region, prokaryotic, score 3.7e-46
550537016136	PS00830 Prokaryotic transcription elongation factors signature 2.
550537016137	HMMPfam hit to PF03449, Transcription elongation factor, GreA/GreB region, prokaryotic, score 3.9e-48
550537016138	PS00829 Prokaryotic transcription elongation factors signature 1.
550537016139	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
550537016140	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
550537016141	HMMPfam hit to PF02113, Peptidase S13, D-Ala-D-Ala carboxypeptidase C, score 1.9e-211
550537016142	GTPase CgtA; Reviewed; Region: obgE; PRK12298
550537016143	GTP1/OBG; Region: GTP1_OBG; pfam01018
550537016144	Obg GTPase; Region: Obg; cd01898
550537016145	G1 box; other site
550537016146	GTP/Mg2+ binding site [chemical binding]; other site
550537016147	Switch I region; other site
550537016148	G2 box; other site
550537016149	G3 box; other site
550537016150	Switch II region; other site
550537016151	G4 box; other site
550537016152	G5 box; other site
550537016153	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 4.4e-38
550537016154	PS00905 GTP1/OBG family signature.
550537016155	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016156	HMMPfam hit to PF01018, GTP1/OBG subdomain, score 4.5e-107
550537016157	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
550537016158	EamA-like transporter family; Region: EamA; pfam00892
550537016159	EamA-like transporter family; Region: EamA; pfam00892
550537016160	10 probable transmembrane helices predicted for SEN3135 by TMHMM2.0 at aa 20-39, 54-73, 86-108, 118-135, 144-166, 170-192, 205-227, 232-254, 261-283 and 293-315
550537016161	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 5.9e-15
550537016162	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 3.5e-27
550537016163	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
550537016164	HMMPfam hit to PF01016, Ribosomal protein L27, score 2.5e-57
550537016165	PS00831 Ribosomal protein L27 signature.
550537016166	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
550537016167	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
550537016168	HMMPfam hit to PF00829, Ribosomal protein L21, score 5.9e-57
550537016169	PS01169 Ribosomal protein L21 signature.
550537016170	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
550537016171	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
550537016172	substrate binding pocket [chemical binding]; other site
550537016173	chain length determination region; other site
550537016174	substrate-Mg2+ binding site; other site
550537016175	catalytic residues [active]
550537016176	aspartate-rich region 1; other site
550537016177	active site lid residues [active]
550537016178	aspartate-rich region 2; other site
550537016179	HMMPfam hit to PF00348, Polyprenyl synthetase, score 1.2e-127
550537016180	PS00723 Polyprenyl synthetases signature 1.
550537016181	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016182	PS00444 Polyprenyl synthetases signature 2.
550537016183	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
550537016184	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
550537016185	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
550537016186	hinge; other site
550537016187	active site
550537016188	HMMPfam hit to PF00275, 3-phosphoshikimate 1-carboxyvinyltransferase, score 3.2e-189
550537016189	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
550537016190	HMMPfam hit to PF01722, BolA-like protein, score 5.1e-38
550537016191	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
550537016192	anti sigma factor interaction site; other site
550537016193	regulatory phosphorylation site [posttranslational modification]; other site
550537016194	HMMPfam hit to PF01740, Sulphate transporter/antisigma-factor antagonist STAS, score 0.00018
550537016195	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
550537016196	HMMPfam hit to PF05494, Toluene tolerance, score 1.8e-97
550537016197	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
550537016198	mce related protein; Region: MCE; pfam02470
550537016199	HMMPfam hit to PF02470, Mammalian cell entry related, score 4.8e-25
550537016200	1 probable transmembrane helix predicted for SEN3144 by TMHMM2.0 at aa 9-31
550537016201	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
550537016202	conserved hypothetical integral membrane protein; Region: TIGR00056
550537016203	HMMPfam hit to PF02405, Protein of unknown function DUF140, score 7.2e-128
550537016204	5 probable transmembrane helices predicted for SEN3145 by TMHMM2.0 at aa 48-70, 85-107, 148-170, 197-219 and 239-258
550537016205	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
550537016206	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
550537016207	Walker A/P-loop; other site
550537016208	ATP binding site [chemical binding]; other site
550537016209	Q-loop/lid; other site
550537016210	ABC transporter signature motif; other site
550537016211	Walker B; other site
550537016212	D-loop; other site
550537016213	H-loop/switch region; other site
550537016214	HMMPfam hit to PF00005, ABC transporter related, score 1.1e-53
550537016215	PS00211 ABC transporters family signature.
550537016216	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016217	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
550537016218	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
550537016219	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
550537016220	HMMPfam hit to PF01699, Sodium/calcium exchanger membrane region, score 5.9e-41
550537016221	9 probable transmembrane helices predicted for SEN3147 by TMHMM2.0 at aa 13-35, 55-77, 86-105, 115-137, 158-180, 190-212, 225-247, 257-276 and 283-305
550537016222	HMMPfam hit to PF01699, Sodium/calcium exchanger membrane region, score 1.2e-37
550537016223	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
550537016224	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
550537016225	putative active site [active]
550537016226	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
550537016227	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016228	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 5.5e-38
550537016229	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 1.2e-19
550537016230	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
550537016231	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
550537016232	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 5.5e-08
550537016233	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
550537016234	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
550537016235	1 probable transmembrane helix predicted for SEN3150 by TMHMM2.0 at aa 7-25
550537016236	HMMPfam hit to PF06835, Protein of unknown function DUF1239, score 3.7e-62
550537016237	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
550537016238	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
550537016239	HMMPfam hit to PF03968, OstA-like protein, score 2e-59
550537016240	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
550537016241	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
550537016242	Walker A/P-loop; other site
550537016243	ATP binding site [chemical binding]; other site
550537016244	Q-loop/lid; other site
550537016245	ABC transporter signature motif; other site
550537016246	Walker B; other site
550537016247	D-loop; other site
550537016248	H-loop/switch region; other site
550537016249	HMMPfam hit to PF00005, ABC transporter related, score 2.3e-56
550537016250	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016251	PS00211 ABC transporters family signature.
550537016252	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
550537016253	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
550537016254	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
550537016255	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
550537016256	HMMPfam hit to PF00309, RNA polymerase sigma factor 54, score 1.6e-19
550537016257	HMMPfam hit to PF04963, RNA polymerase sigma factor 54, core-binding, score 1.8e-124
550537016258	HMMPfam hit to PF04552, RNA polymerase sigma factor 54, DNA-binding, score 1.1e-107
550537016259	PS00717 Sigma-54 factors family signature 1.
550537016260	PS00718 Sigma-54 factors family signature 2.
550537016261	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
550537016262	30S subunit binding site; other site
550537016263	HMMPfam hit to PF02482, Ribosomal protein S30Ae/sigma 54 modulation protein, score 1e-52
550537016264	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537016265	active site
550537016266	phosphorylation site [posttranslational modification]
550537016267	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 1.3e-65
550537016268	PS00372 PTS EIIA domains phosphorylation site signature 2.
550537016269	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
550537016270	HMMPfam hit to PF03668, P-loop ATPase protein, score 1.2e-216
550537016271	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016272	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
550537016273	dimerization domain swap beta strand [polypeptide binding]; other site
550537016274	regulatory protein interface [polypeptide binding]; other site
550537016275	active site
550537016276	regulatory phosphorylation site [posttranslational modification]; other site
550537016277	HMMPfam hit to PF00381, Phosphotransferase system, phosphocarrier HPr protein, score 8.6e-43
550537016278	PS00369 PTS HPR component histidine phosphorylation site signature.
550537016279	PS00589 PTS HPR component serine phosphorylation site signature.
550537016280	hypothetical protein; Provisional; Region: PRK10345
550537016281	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
550537016282	Transglycosylase; Region: Transgly; cl17702
550537016283	HMMPfam hit to PF00912, Glycosyl transferase, family 51, score 3.2e-79
550537016284	1 probable transmembrane helix predicted for SEN3159 by TMHMM2.0 at aa 19-41
550537016285	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
550537016286	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
550537016287	conserved cys residue [active]
550537016288	HMMPfam hit to PF01965, ThiJ/PfpI, score 3e-24
550537016289	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
550537016290	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537016291	putative active site [active]
550537016292	heme pocket [chemical binding]; other site
550537016293	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537016294	dimer interface [polypeptide binding]; other site
550537016295	phosphorylation site [posttranslational modification]
550537016296	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537016297	ATP binding site [chemical binding]; other site
550537016298	Mg2+ binding site [ion binding]; other site
550537016299	G-X-G motif; other site
550537016300	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537016301	active site
550537016302	phosphorylation site [posttranslational modification]
550537016303	intermolecular recognition site; other site
550537016304	dimerization interface [polypeptide binding]; other site
550537016305	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
550537016306	putative binding surface; other site
550537016307	active site
550537016308	HMMPfam hit to PF01627, Hpt, score 4.5e-13
550537016309	HMMPfam hit to PF00072, Response regulator receiver, score 7.4e-37
550537016310	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.3e-41
550537016311	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 4.2e-21
550537016312	HMMPfam hit to PF00989, PAS fold, score 2.9e-27
550537016313	2 probable transmembrane helices predicted for SEN3161 by TMHMM2.0 at aa 20-42 and 55-77
550537016314	radical SAM protein, TIGR01212 family; Region: TIGR01212
550537016315	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537016316	FeS/SAM binding site; other site
550537016317	HMMPfam hit to PF04055, Radical SAM, score 9.3e-13
550537016318	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
550537016319	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
550537016320	active site
550537016321	dimer interface [polypeptide binding]; other site
550537016322	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
550537016323	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
550537016324	active site
550537016325	FMN binding site [chemical binding]; other site
550537016326	substrate binding site [chemical binding]; other site
550537016327	3Fe-4S cluster binding site [ion binding]; other site
550537016328	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
550537016329	domain interface; other site
550537016330	HMMPfam hit to PF00310, Glutamine amidotransferase, class-II, score 1.6e-232
550537016331	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016332	HMMPfam hit to PF04898, Glutamate synthase, central-N, score 1.4e-175
550537016333	HMMPfam hit to PF01645, Glutamate synthase, central-C, score 6.4e-244
550537016334	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016335	HMMPfam hit to PF01493, Glutamate synthase, alpha subunit, C-terminal, score 9.9e-106
550537016336	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
550537016337	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537016338	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537016339	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 5.1e-26
550537016340	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016341	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 0.0015
550537016342	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
550537016343	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
550537016344	HMMPfam hit to PF06250, Protein of unknown function DUF1016, score 1.4e-196
550537016345	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
550537016346	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
550537016347	Na binding site [ion binding]; other site
550537016348	putative substrate binding site [chemical binding]; other site
550537016349	HMMPfam hit to PF02133, Permease for cytosine/purines, uracil, thiamine, allantoin, score 4.6e-96
550537016350	12 probable transmembrane helices predicted for SEN3166 by TMHMM2.0 at aa 21-43, 53-75, 96-118, 128-150, 152-174, 189-211, 223-245, 255-277, 296-318, 323-345, 358-375 and 380-402
550537016351	cytosine deaminase; Provisional; Region: PRK09230
550537016352	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
550537016353	active site
550537016354	HMMPfam hit to PF07969, Amidohydrolase 3, score 1.6e-78
550537016355	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
550537016356	HMMPfam hit to PF04074, Conserved hypothetical protein CHP00022, score 1.9e-71
550537016357	N-acetylmannosamine kinase; Provisional; Region: PRK05082
550537016358	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537016359	nucleotide binding site [chemical binding]; other site
550537016360	HMMPfam hit to PF00480, ROK, score 9.1e-71
550537016361	PS01125 ROK family signature.
550537016362	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
550537016363	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
550537016364	putative active site cavity [active]
550537016365	HMMPfam hit to PF04131, N-acetylmannosamine-6-phosphate epimerase, score 3.6e-126
550537016366	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016367	putative sialic acid transporter; Provisional; Region: PRK03893
550537016368	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537016369	putative substrate translocation pore; other site
550537016370	14 probable transmembrane helices predicted for SEN3171 by TMHMM2.0 at aa 20-42, 57-79, 86-108, 112-134, 147-166, 171-190, 224-243, 248-267, 280-302, 312-334, 347-369, 373-395, 404-426 and 431-453
550537016371	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 7.3e-39
550537016372	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016373	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016374	N-acetylneuraminate lyase; Provisional; Region: PRK04147
550537016375	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
550537016376	inhibitor site; inhibition site
550537016377	active site
550537016378	dimer interface [polypeptide binding]; other site
550537016379	catalytic residue [active]
550537016380	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase, score 2.7e-146
550537016381	PS00666 Dihydrodipicolinate synthetase signature 2.
550537016382	PS00665 Dihydrodipicolinate synthetase signature 1.
550537016383	transcriptional regulator NanR; Provisional; Region: PRK03837
550537016384	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537016385	DNA-binding site [nucleotide binding]; DNA binding site
550537016386	FCD domain; Region: FCD; pfam07729
550537016387	HMMPfam hit to PF07729, GntR, C-terminal, score 2.5e-30
550537016388	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 4.7e-26
550537016389	PS00043 Bacterial regulatory proteins, gntR family signature.
550537016390	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
550537016391	HMMPfam hit to PF04386, Stringent starvation protein B, score 9.3e-96
550537016392	stringent starvation protein A; Provisional; Region: sspA; PRK09481
550537016393	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
550537016394	C-terminal domain interface [polypeptide binding]; other site
550537016395	putative GSH binding site (G-site) [chemical binding]; other site
550537016396	dimer interface [polypeptide binding]; other site
550537016397	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
550537016398	dimer interface [polypeptide binding]; other site
550537016399	N-terminal domain interface [polypeptide binding]; other site
550537016400	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 1.5e-14
550537016401	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 5.3e-24
550537016402	Family of unknown function (DUF695); Region: DUF695; pfam05117
550537016403	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
550537016404	HMMPfam hit to PF06877, Protein of unknown function DUF1260, score 2.5e-39
550537016405	HMMPfam hit to PF05117, Conserved hypothetical protein CHP01619, score 2e-80
550537016406	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
550537016407	HMMPfam hit to PF00380, Ribosomal protein S9, score 1.2e-75
550537016408	PS00360 Ribosomal protein S9 signature.
550537016409	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
550537016410	23S rRNA interface [nucleotide binding]; other site
550537016411	L3 interface [polypeptide binding]; other site
550537016412	HMMPfam hit to PF00572, Ribosomal protein L13, score 9.4e-89
550537016413	PS00783 Ribosomal protein L13 signature.
550537016414	Predicted ATPase [General function prediction only]; Region: COG1485
550537016415	HMMPfam hit to PF03969, AFG1-like ATPase, score 1.4e-220
550537016416	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016417	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
550537016418	hypothetical protein; Provisional; Region: PRK11677
550537016419	1 probable transmembrane helix predicted for SEN3180 by TMHMM2.0 at aa 4-26
550537016420	HMMPfam hit to PF06295, Protein of unknown function DUF1043, score 1.1e-83
550537016421	serine endoprotease; Provisional; Region: PRK10139
550537016422	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
550537016423	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
550537016424	protein binding site [polypeptide binding]; other site
550537016425	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
550537016426	1 probable transmembrane helix predicted for SEN3181 by TMHMM2.0 at aa 7-29
550537016427	HMMPfam hit to PF00089, Peptidase S1 and S6, chymotrypsin/Hap, score 3.9e-21
550537016428	HMMPfam hit to PF00595, PDZ/DHR/GLGF, score 6.4e-21
550537016429	HMMPfam hit to PF00595, PDZ/DHR/GLGF, score 3.7e-13
550537016430	serine endoprotease; Provisional; Region: PRK10898
550537016431	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
550537016432	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
550537016433	1 probable transmembrane helix predicted for SEN3182 by TMHMM2.0 at aa 5-27
550537016434	HMMPfam hit to PF00089, Peptidase S1 and S6, chymotrypsin/Hap, score 8e-28
550537016435	HMMPfam hit to PF00595, PDZ/DHR/GLGF, score 4.9e-16
550537016436	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
550537016437	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
550537016438	9 probable transmembrane helices predicted for SEN3184 by TMHMM2.0 at aa 13-35, 122-144, 159-178, 180-202, 222-244, 266-288, 308-327, 339-361 and 409-431
550537016439	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit, score 2.5e-289
550537016440	oxaloacetate decarboxylase; Provisional; Region: PRK14040
550537016441	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
550537016442	active site
550537016443	catalytic residues [active]
550537016444	metal binding site [ion binding]; metal-binding site
550537016445	homodimer binding site [polypeptide binding]; other site
550537016446	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
550537016447	carboxyltransferase (CT) interaction site; other site
550537016448	biotinylation site [posttranslational modification]; other site
550537016449	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 2e-27
550537016450	PS00188 Biotin-requiring enzymes attachment site.
550537016451	HMMPfam hit to PF02436, Conserved carboxylase region, score 1.5e-97
550537016452	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
550537016453	HMMPfam hit to PF00682, Pyruvate carboxyltransferase, score 1.5e-90
550537016454	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
550537016455	HMMPfam hit to PF04277, Sodium ion-translocating decarboxylase, score 1.1e-31
550537016456	1 probable transmembrane helix predicted for SEN3186 by TMHMM2.0 at aa 11-33
550537016457	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
550537016458	HMMPfam hit to PF05683, Fe-S type hydro-lyases tartrate/fumarate beta region, score 7.6e-35
550537016459	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
550537016460	HMMPfam hit to PF05681, Fe-S type hydro-lyases tartrate/fumarate alpha region, score 3.6e-143
550537016461	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016462	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
550537016463	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
550537016464	transmembrane helices; other site
550537016465	11 probable transmembrane helices predicted for SEN3189 by TMHMM2.0 at aa 4-20, 25-44, 49-71, 92-121, 136-158, 171-193, 244-266, 279-301, 316-338, 359-378 and 398-420
550537016466	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016467	HMMPfam hit to PF03600, Divalent ion symporter, score 4.8e-09
550537016468	Transcriptional regulators [Transcription]; Region: GntR; COG1802
550537016469	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537016470	DNA-binding site [nucleotide binding]; DNA binding site
550537016471	FCD domain; Region: FCD; pfam07729
550537016472	HMMPfam hit to PF07729, GntR, C-terminal, score 9.5e-14
550537016473	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 3.5e-16
550537016474	Transcriptional regulators [Transcription]; Region: GntR; COG1802
550537016475	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537016476	DNA-binding site [nucleotide binding]; DNA binding site
550537016477	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 9.9e-18
550537016478	malate dehydrogenase; Provisional; Region: PRK05086
550537016479	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
550537016480	NAD binding site [chemical binding]; other site
550537016481	dimerization interface [polypeptide binding]; other site
550537016482	Substrate binding site [chemical binding]; other site
550537016483	HMMPfam hit to PF02866, Lactate/malate dehydrogenase, score 6.7e-74
550537016484	PS00068 Malate dehydrogenase active site signature.
550537016485	HMMPfam hit to PF00056, Lactate/malate dehydrogenase, score 1.8e-71
550537016486	arginine repressor; Provisional; Region: PRK05066
550537016487	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
550537016488	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
550537016489	HMMPfam hit to PF01316, Arginine repressor, score 4.6e-32
550537016490	HMMPfam hit to PF02863, Arginine repressor, score 1.4e-25
550537016491	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537016492	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 6.3e-57
550537016493	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537016494	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 2.4e-54
550537016495	1 probable transmembrane helix predicted for SEN3195 by TMHMM2.0 at aa 5-24
550537016496	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
550537016497	RNAase interaction site [polypeptide binding]; other site
550537016498	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
550537016499	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
550537016500	10 probable transmembrane helices predicted for SEN3197 by TMHMM2.0 at aa 13-33, 38-60, 67-89, 93-112, 119-136, 151-168, 370-392, 407-426, 433-452 and 481-503
550537016501	HMMPfam hit to PF04632, Fusaric acid resistance protein conserved region, score 5.2e-50
550537016502	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016503	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
550537016504	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537016505	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537016506	HMMPfam hit to PF00529, Secretion protein HlyD, score 6.9e-42
550537016507	1 probable transmembrane helix predicted for SEN3198 by TMHMM2.0 at aa 12-31
550537016508	efflux system membrane protein; Provisional; Region: PRK11594
550537016509	2 probable transmembrane helices predicted for SEN3199 by TMHMM2.0 at aa 7-29 and 44-66
550537016510	HMMPfam hit to PF07869, Protein of unknown function DUF1656, score 1.6e-23
550537016511	transcriptional regulator; Provisional; Region: PRK10632
550537016512	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537016513	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
550537016514	putative effector binding pocket; other site
550537016515	dimerization interface [polypeptide binding]; other site
550537016516	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 4.8e-18
550537016517	PS00044 Bacterial regulatory proteins, lysR family signature.
550537016518	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.4e-43
550537016519	protease TldD; Provisional; Region: tldD; PRK10735
550537016520	HMMPfam hit to PF01523, Peptidase U62, modulator of DNA gyrase, score 1.6e-112
550537016521	hypothetical protein; Provisional; Region: PRK10899
550537016522	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
550537016523	ribonuclease G; Provisional; Region: PRK11712
550537016524	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
550537016525	homodimer interface [polypeptide binding]; other site
550537016526	oligonucleotide binding site [chemical binding]; other site
550537016527	HMMPfam hit to PF00575, S1, RNA binding, score 1.2e-19
550537016528	Maf-like protein; Region: Maf; pfam02545
550537016529	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
550537016530	active site
550537016531	dimer interface [polypeptide binding]; other site
550537016532	HMMPfam hit to PF02545, Maf-like protein, score 3.9e-99
550537016533	rod shape-determining protein MreD; Provisional; Region: PRK11060
550537016534	HMMPfam hit to PF04093, Rod shape-determining protein MreD, score 1.8e-63
550537016535	5 probable transmembrane helices predicted for SEN3205 by TMHMM2.0 at aa 11-28, 32-51, 58-80, 100-122 and 135-152
550537016536	rod shape-determining protein MreC; Region: mreC; TIGR00219
550537016537	rod shape-determining protein MreC; Region: MreC; pfam04085
550537016538	HMMPfam hit to PF04085, Rod shape-determining protein MreC, score 1.3e-72
550537016539	1 probable transmembrane helix predicted for SEN3206 by TMHMM2.0 at aa 13-35
550537016540	rod shape-determining protein MreB; Provisional; Region: PRK13927
550537016541	MreB and similar proteins; Region: MreB_like; cd10225
550537016542	nucleotide binding site [chemical binding]; other site
550537016543	Mg binding site [ion binding]; other site
550537016544	putative protofilament interaction site [polypeptide binding]; other site
550537016545	RodZ interaction site [polypeptide binding]; other site
550537016546	HMMPfam hit to PF06723, Cell shape determining protein MreB/Mrl, score 7.8e-239
550537016547	regulatory protein CsrD; Provisional; Region: PRK11059
550537016548	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537016549	metal binding site [ion binding]; metal-binding site
550537016550	active site
550537016551	I-site; other site
550537016552	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537016553	HMMPfam hit to PF00563, EAL, score 2.4e-58
550537016554	HMMPfam hit to PF00990, GGDEF, score 2e-31
550537016555	2 probable transmembrane helices predicted for SEN3209 by TMHMM2.0 at aa 10-32 and 130-152
550537016556	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016557	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
550537016558	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
550537016559	NADP binding site [chemical binding]; other site
550537016560	dimer interface [polypeptide binding]; other site
550537016561	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 4.2e-10
550537016562	PS00213 Lipocalin signature.
550537016563	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537016564	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 1.4e-13
550537016565	TMAO/DMSO reductase; Reviewed; Region: PRK05363
550537016566	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
550537016567	Moco binding site; other site
550537016568	metal coordination site [ion binding]; other site
550537016569	HMMPfam hit to PF00174, Oxidoreductase, molybdopterin binding, score 7e-68
550537016570	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
550537016571	6 probable transmembrane helices predicted for SEN3212 by TMHMM2.0 at aa 13-30, 45-67, 80-102, 117-139, 151-168 and 172-189
550537016572	HMMPfam hit to PF01794, Ferric reductase-like transmembrane component, N-terminal, score 3.1e-29
550537016573	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
550537016574	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
550537016575	carboxyltransferase (CT) interaction site; other site
550537016576	biotinylation site [posttranslational modification]; other site
550537016577	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 2.5e-35
550537016578	PS00188 Biotin-requiring enzymes attachment site.
550537016579	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
550537016580	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
550537016581	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
550537016582	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
550537016583	HMMPfam hit to PF00289, Carbamoyl-phosphate synthetase large chain, N-terminal, score 1.3e-56
550537016584	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain, ATP-binding, score 1.2e-129
550537016585	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
550537016586	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
550537016587	HMMPfam hit to PF02785, Biotin carboxylase, C-terminal, score 1.8e-65
550537016588	hypothetical protein; Provisional; Region: PRK10633
550537016589	HMMPfam hit to PF06196, Protein of unknown function DUF997, score 3e-44
550537016590	2 probable transmembrane helices predicted for SEN3215 by TMHMM2.0 at aa 13-32 and 42-64
550537016591	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
550537016592	Na binding site [ion binding]; other site
550537016593	13 probable transmembrane helices predicted for SEN3216 by TMHMM2.0 at aa 5-24, 37-59, 72-94, 123-145, 160-182, 189-211, 233-255, 268-290, 319-341, 369-386, 391-413, 420-442 and 447-466
550537016594	HMMPfam hit to PF00474, Na+/solute symporter, score 4.1e-197
550537016595	PS00456 Sodium:solute symporter family signature 1.
550537016596	PS00457 Sodium:solute symporter family signature 2.
550537016597	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
550537016598	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
550537016599	HMMPfam hit to PF06325, Ribosomal L11 methyltransferase, score 1.7e-175
550537016600	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016601	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
550537016602	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
550537016603	FMN binding site [chemical binding]; other site
550537016604	active site
550537016605	catalytic residues [active]
550537016606	substrate binding site [chemical binding]; other site
550537016607	HMMPfam hit to PF01207, Dihydrouridine synthase, DuS, score 6.6e-159
550537016608	PS01136 Uncharacterized protein family UPF0034 signature.
550537016609	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
550537016610	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
550537016611	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 1.1e-14
550537016612	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
550537016613	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537016614	DNA methylase; Region: N6_N4_Mtase; pfam01555
550537016615	HMMPfam hit to PF01555, DNA methylase N-4/N-6, score 1.6e-81
550537016616	PS00092 N-6 Adenine-specific DNA methylases signature.
550537016617	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
550537016618	1 probable transmembrane helix predicted for SEN3221 by TMHMM2.0 at aa 7-29
550537016619	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
550537016620	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
550537016621	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
550537016622	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537016623	metal binding site [ion binding]; metal-binding site
550537016624	active site
550537016625	I-site; other site
550537016626	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537016627	7 probable transmembrane helices predicted for SEN3222 by TMHMM2.0 at aa 10-27, 40-62, 77-99, 112-134, 139-161, 174-193 and 213-235
550537016628	HMMPfam hit to PF03707, MHYT, score 2.4e-17
550537016629	HMMPfam hit to PF03707, MHYT, score 4.9e-16
550537016630	HMMPfam hit to PF03707, MHYT, score 3.9e-06
550537016631	HMMPfam hit to PF00990, GGDEF, score 1.2e-58
550537016632	HMMPfam hit to PF00563, EAL, score 6.4e-121
550537016633	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
550537016634	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537016635	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
550537016636	HMMPfam hit to PF08361, Transcriptional regulator, MAATS, C-terminal, score 1.5e-74
550537016637	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 1.3e-20
550537016638	PS01081 Bacterial regulatory proteins, tetR family signature.
550537016639	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
550537016640	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537016641	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537016642	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016643	HMMPfam hit to PF00529, Secretion protein HlyD, score 1.8e-96
550537016644	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
550537016645	HMMPfam hit to PF00873, Acriflavin resistance protein, score 0
550537016646	12 probable transmembrane helices predicted for SEN3225 by TMHMM2.0 at aa 9-31, 337-359, 366-388, 392-414, 438-460, 470-492, 541-563, 872-891, 898-920, 925-947, 974-996 and 1006-1028
550537016647	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
550537016648	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016649	1 probable transmembrane helix predicted for SEN3226 by TMHMM2.0 at aa 50-72
550537016650	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
550537016651	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
550537016652	trimer interface [polypeptide binding]; other site
550537016653	putative metal binding site [ion binding]; other site
550537016654	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1e+02
550537016655	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 24
550537016656	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.71
550537016657	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 7.8
550537016658	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
550537016659	HMMPfam hit to PF07369, Protein of unknown function DUF1488, score 1.4e-58
550537016660	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
550537016661	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
550537016662	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
550537016663	shikimate binding site; other site
550537016664	NAD(P) binding site [chemical binding]; other site
550537016665	HMMPfam hit to PF01488, Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase, score 1.8e-30
550537016666	HMMPfam hit to PF08501, Shikimate dehydrogenase substrate binding, N-terminal, score 1e-26
550537016667	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
550537016668	HMMPfam hit to PF01300, SUA5/yciO/yrdC, N-terminal, score 4.4e-46
550537016669	PS01147 SUA5/yciO/yrdC family signature.
550537016670	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
550537016671	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
550537016672	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
550537016673	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
550537016674	HMMPfam hit to PF01396, DNA topoisomerase, type IA, zn finger, score 4.7e-14
550537016675	HMMPfam hit to PF01396, DNA topoisomerase, type IA, zn finger, score 5.1e-16
550537016676	HMMPfam hit to PF01396, DNA topoisomerase, type IA, zn finger, score 4.5e-17
550537016677	hypothetical protein; Validated; Region: PRK03430
550537016678	HMMPfam hit to PF04361, Protein of unknown function DUF494, score 3.2e-119
550537016679	hypothetical protein; Provisional; Region: PRK10736
550537016680	DNA protecting protein DprA; Region: dprA; TIGR00732
550537016681	HMMPfam hit to PF02481, SMF protein, score 1.2e-109
550537016682	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016683	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
550537016684	active site
550537016685	catalytic residues [active]
550537016686	metal binding site [ion binding]; metal-binding site
550537016687	HMMPfam hit to PF01327, Formylmethionine deformylase, score 4.4e-89
550537016688	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
550537016689	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
550537016690	putative active site [active]
550537016691	substrate binding site [chemical binding]; other site
550537016692	putative cosubstrate binding site; other site
550537016693	catalytic site [active]
550537016694	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
550537016695	substrate binding site [chemical binding]; other site
550537016696	HMMPfam hit to PF00551, Formyl transferase, N-terminal, score 5.7e-83
550537016697	PS00373 Phosphoribosylglycinamide formyltransferase active site.
550537016698	HMMPfam hit to PF02911, Formyl transferase, C-terminal, score 4.7e-47
550537016699	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
550537016700	putative RNA binding site [nucleotide binding]; other site
550537016701	16S rRNA methyltransferase B; Provisional; Region: PRK10901
550537016702	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537016703	S-adenosylmethionine binding site [chemical binding]; other site
550537016704	HMMPfam hit to PF01029, NusB/RsmB/TIM44, score 7.3e-43
550537016705	HMMPfam hit to PF01189, Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, score 5.4e-139
550537016706	PS01153 NOL1/NOP2/sun family signature.
550537016707	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
550537016708	TrkA-N domain; Region: TrkA_N; pfam02254
550537016709	TrkA-C domain; Region: TrkA_C; pfam02080
550537016710	TrkA-N domain; Region: TrkA_N; pfam02254
550537016711	TrkA-C domain; Region: TrkA_C; pfam02080
550537016712	HMMPfam hit to PF02254, TrkA-N, score 5.9e-36
550537016713	HMMPfam hit to PF02080, TrkA-C, score 1.6e-11
550537016714	HMMPfam hit to PF02254, TrkA-N, score 2.3e-35
550537016715	HMMPfam hit to PF02080, TrkA-C, score 4.1e-11
550537016716	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
550537016717	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
550537016718	HMMPfam hit to PF01741, Large-conductance mechanosensitive channel, score 9.5e-88
550537016719	PS01327 Large-conductance mechanosensitive channels mscL family signature.
550537016720	2 probable transmembrane helices predicted for SEN3238 by TMHMM2.0 at aa 20-42 and 77-99
550537016721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
550537016722	HMMPfam hit to PF03889, Protein of unknown function DUF331, score 3.7e-30
550537016723	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
550537016724	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
550537016725	DNA binding residues [nucleotide binding]
550537016726	dimer interface [polypeptide binding]; other site
550537016727	metal binding site [ion binding]; metal-binding site
550537016728	HMMPfam hit to PF09278, Transcription regulator MerR, DNA binding, score 6.9e-25
550537016729	HMMPfam hit to PF00376, Bacterial regulatory protein, MerR, score 6.1e-10
550537016730	PS00552 Bacterial regulatory proteins, merR family signature.
550537016731	hypothetical protein; Provisional; Region: PRK10203
550537016732	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
550537016733	HMMPfam hit to PF01196, Ribosomal protein L17, score 6.2e-67
550537016734	PS01167 Ribosomal protein L17 signature.
550537016735	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
550537016736	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
550537016737	alphaNTD homodimer interface [polypeptide binding]; other site
550537016738	alphaNTD - beta interaction site [polypeptide binding]; other site
550537016739	alphaNTD - beta' interaction site [polypeptide binding]; other site
550537016740	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
550537016741	HMMPfam hit to PF03118, RNA polymerase, alpha subunit, C-terminal, score 1.9e-35
550537016742	HMMPfam hit to PF01193, RNA polymerase, dimerisation, score 8.2e-24
550537016743	HMMPfam hit to PF01000, RNA polymerase, insert, score 2.1e-58
550537016744	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
550537016745	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
550537016746	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537016747	RNA binding surface [nucleotide binding]; other site
550537016748	HMMPfam hit to PF01479, RNA-binding S4, score 2e-21
550537016749	PS00632 Ribosomal protein S4 signature.
550537016750	HMMPfam hit to PF00163, Ribosomal protein S4, score 1.1e-37
550537016751	30S ribosomal protein S11; Validated; Region: PRK05309
550537016752	HMMPfam hit to PF00411, Ribosomal protein S11, score 4.4e-74
550537016753	PS00054 Ribosomal protein S11 signature.
550537016754	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
550537016755	30S ribosomal protein S13; Region: bact_S13; TIGR03631
550537016756	HMMPfam hit to PF00416, Ribosomal protein S13, score 1.8e-63
550537016757	PS00646 Ribosomal protein S13 signature.
550537016758	PS00061 Short-chain dehydrogenases/reductases family signature.
550537016759	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
550537016760	HMMPfam hit to PF00444, Ribosomal protein L36, score 6e-16
550537016761	PS00828 Ribosomal protein L36 signature.
550537016762	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
550537016763	SecY translocase; Region: SecY; pfam00344
550537016764	HMMPfam hit to PF00344, SecY protein, score 7.2e-212
550537016765	10 probable transmembrane helices predicted for SEN3248 by TMHMM2.0 at aa 22-44, 76-98, 119-138, 153-175, 182-204, 215-237, 274-296, 316-338, 373-392 and 397-414
550537016766	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
550537016767	PS00756 Protein secY signature 2.
550537016768	PS00755 Protein secY signature 1.
550537016769	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
550537016770	HMMPfam hit to PF00256, Ribosomal protein L15, score 2.5e-10
550537016771	PS00475 Ribosomal protein L15 signature.
550537016772	HMMPfam hit to PF01305, Ribosomal protein L15, score 1.3e-56
550537016773	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
550537016774	23S rRNA binding site [nucleotide binding]; other site
550537016775	HMMPfam hit to PF00327, Ribosomal protein L30, score 1.1e-23
550537016776	PS00634 Ribosomal protein L30 signature.
550537016777	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
550537016778	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
550537016779	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
550537016780	HMMPfam hit to PF03719, Ribosomal protein S5, C-terminal, score 5.8e-43
550537016781	HMMPfam hit to PF00333, Ribosomal protein S5, N-terminal, score 4.8e-41
550537016782	PS00585 Ribosomal protein S5 signature.
550537016783	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
550537016784	23S rRNA interface [nucleotide binding]; other site
550537016785	5S rRNA interface [nucleotide binding]; other site
550537016786	L27 interface [polypeptide binding]; other site
550537016787	L5 interface [polypeptide binding]; other site
550537016788	HMMPfam hit to PF00861, Ribosomal protein L18/L5, score 2.1e-52
550537016789	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
550537016790	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
550537016791	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
550537016792	HMMPfam hit to PF00347, Ribosomal protein L6, score 1.9e-30
550537016793	PS00525 Ribosomal protein L6 signature 1.
550537016794	HMMPfam hit to PF00347, Ribosomal protein L6, score 3.7e-21
550537016795	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
550537016796	HMMPfam hit to PF00410, Ribosomal protein S8, score 7.2e-72
550537016797	PS00294 Prenyl group binding site (CAAX box).
550537016798	PS00053 Ribosomal protein S8 signature.
550537016799	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
550537016800	HMMPfam hit to PF00253, Ribosomal protein S14, score 9e-25
550537016801	PS00527 Ribosomal protein S14 signature.
550537016802	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
550537016803	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
550537016804	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
550537016805	HMMPfam hit to PF00673, Ribosomal protein L5, score 1.6e-58
550537016806	HMMPfam hit to PF00281, Ribosomal protein L5, score 6.6e-33
550537016807	PS00358 Ribosomal protein L5 signature.
550537016808	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
550537016809	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
550537016810	RNA binding site [nucleotide binding]; other site
550537016811	HMMPfam hit to PF00467, KOW, score 6.9e-07
550537016812	PS01108 Ribosomal protein L24 signature.
550537016813	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
550537016814	HMMPfam hit to PF00238, Ribosomal protein L14b/L23e, score 5.3e-81
550537016815	PS00049 Ribosomal protein L14 signature.
550537016816	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
550537016817	HMMPfam hit to PF00366, Ribosomal protein S17, score 1.5e-42
550537016818	PS00056 Ribosomal protein S17 signature.
550537016819	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
550537016820	23S rRNA interface [nucleotide binding]; other site
550537016821	putative translocon interaction site; other site
550537016822	signal recognition particle (SRP54) interaction site; other site
550537016823	L23 interface [polypeptide binding]; other site
550537016824	trigger factor interaction site; other site
550537016825	HMMPfam hit to PF00831, Ribosomal protein L29, score 2.6e-28
550537016826	PS00579 Ribosomal protein L29 signature.
550537016827	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
550537016828	23S rRNA interface [nucleotide binding]; other site
550537016829	5S rRNA interface [nucleotide binding]; other site
550537016830	putative antibiotic binding site [chemical binding]; other site
550537016831	L25 interface [polypeptide binding]; other site
550537016832	L27 interface [polypeptide binding]; other site
550537016833	HMMPfam hit to PF00252, Ribosomal protein L16, score 1.6e-92
550537016834	PS00701 Ribosomal protein L16 signature 2.
550537016835	PS00586 Ribosomal protein L16 signature 1.
550537016836	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
550537016837	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
550537016838	G-X-X-G motif; other site
550537016839	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
550537016840	HMMPfam hit to PF00189, Ribosomal protein S3, C-terminal, score 7.4e-54
550537016841	PS00548 Ribosomal protein S3 signature.
550537016842	HMMPfam hit to PF07650, K Homology, type 2, score 1.9e-19
550537016843	HMMPfam hit to PF00417, Ribosomal protein S3, N-terminal, score 5.8e-29
550537016844	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
550537016845	protein-rRNA interface [nucleotide binding]; other site
550537016846	putative translocon binding site; other site
550537016847	HMMPfam hit to PF00237, Ribosomal protein L22/L17, score 3.2e-60
550537016848	PS00464 Ribosomal protein L22 signature.
550537016849	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
550537016850	HMMPfam hit to PF00203, Ribosomal protein S19/S15, score 1.3e-53
550537016851	PS00323 Ribosomal protein S19 signature.
550537016852	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
550537016853	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
550537016854	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
550537016855	HMMPfam hit to PF03947, Ribosomal protein L2, score 3.3e-82
550537016856	PS00467 Ribosomal protein L2 signature.
550537016857	HMMPfam hit to PF00181, Ribosomal protein L2, score 1.8e-47
550537016858	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
550537016859	HMMPfam hit to PF00276, Ribosomal protein L25/L23, score 2.3e-44
550537016860	PS00050 Ribosomal protein L23 signature.
550537016861	PS00430 TonB-dependent receptor proteins signature 1.
550537016862	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
550537016863	HMMPfam hit to PF00573, Ribosomal protein L4/L1e, score 1.6e-55
550537016864	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
550537016865	HMMPfam hit to PF00297, Ribosomal protein L3, score 4.8e-108
550537016866	PS00474 Ribosomal protein L3 signature.
550537016867	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
550537016868	HMMPfam hit to PF00338, Ribosomal protein S10, score 5.8e-62
550537016869	PS00361 Ribosomal protein S10 signature.
550537016870	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
550537016871	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
550537016872	4 probable transmembrane helices predicted for SEN3270 by TMHMM2.0 at aa 4-21, 55-74, 101-123 and 130-152
550537016873	HMMPfam hit to PF01478, Peptidase A24A, prepilin type IV, score 1.1e-24
550537016874	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537016875	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016876	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
550537016877	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
550537016878	heme binding site [chemical binding]; other site
550537016879	ferroxidase pore; other site
550537016880	ferroxidase diiron center [ion binding]; other site
550537016881	HMMPfam hit to PF00210, Ferritin and Dps, score 2.2e-50
550537016882	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
550537016883	HMMPfam hit to PF04324, BFD-like [2Fe-2S]-binding region, score 1.9e-19
550537016884	elongation factor Tu; Reviewed; Region: PRK00049
550537016885	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
550537016886	G1 box; other site
550537016887	GEF interaction site [polypeptide binding]; other site
550537016888	GTP/Mg2+ binding site [chemical binding]; other site
550537016889	Switch I region; other site
550537016890	G2 box; other site
550537016891	G3 box; other site
550537016892	Switch II region; other site
550537016893	G4 box; other site
550537016894	G5 box; other site
550537016895	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
550537016896	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
550537016897	Antibiotic Binding Site [chemical binding]; other site
550537016898	HMMPfam hit to PF03143, Translation elongation factor EFTu/EF1A, C-terminal, score 1e-60
550537016899	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 2.3e-26
550537016900	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 3.3e-96
550537016901	PS00301 GTP-binding elongation factors signature.
550537016902	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016903	elongation factor G; Reviewed; Region: PRK00007
550537016904	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
550537016905	G1 box; other site
550537016906	putative GEF interaction site [polypeptide binding]; other site
550537016907	GTP/Mg2+ binding site [chemical binding]; other site
550537016908	Switch I region; other site
550537016909	G2 box; other site
550537016910	G3 box; other site
550537016911	Switch II region; other site
550537016912	G4 box; other site
550537016913	G5 box; other site
550537016914	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
550537016915	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
550537016916	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
550537016917	HMMPfam hit to PF00679, Translation elongation factor EFG/EF2, C-terminal, score 3.7e-47
550537016918	HMMPfam hit to PF03764, Translation elongation factor EFG/EF2, domain IV, score 1.6e-67
550537016919	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 4.9e-20
550537016920	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 4e-113
550537016921	PS00301 GTP-binding elongation factors signature.
550537016922	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016923	30S ribosomal protein S7; Validated; Region: PRK05302
550537016924	HMMPfam hit to PF00177, Ribosomal protein S7, score 1.1e-88
550537016925	PS00052 Ribosomal protein S7 signature.
550537016926	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
550537016927	S17 interaction site [polypeptide binding]; other site
550537016928	S8 interaction site; other site
550537016929	16S rRNA interaction site [nucleotide binding]; other site
550537016930	streptomycin interaction site [chemical binding]; other site
550537016931	23S rRNA interaction site [nucleotide binding]; other site
550537016932	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
550537016933	HMMPfam hit to PF00164, Ribosomal protein S12/S23, score 3.4e-75
550537016934	PS00055 Ribosomal protein S12 signature.
550537016935	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
550537016936	HMMPfam hit to PF04077, DsrH like protein, score 1.6e-30
550537016937	sulfur relay protein TusC; Validated; Region: PRK00211
550537016938	HMMPfam hit to PF02635, DsrE-like protein, score 2.7e-41
550537016939	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
550537016940	HMMPfam hit to PF02635, DsrE-like protein, score 2.3e-55
550537016941	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
550537016942	YheO-like PAS domain; Region: PAS_6; pfam08348
550537016943	HTH domain; Region: HTH_22; pfam13309
550537016944	HMMPfam hit to PF08348, YheO-like, score 2.7e-59
550537016945	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
550537016946	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
550537016947	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
550537016948	HMMPfam hit to PF00254, Peptidyl-prolyl cis-trans isomerase, FKBP-type, score 2.9e-46
550537016949	PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2.
550537016950	HMMPfam hit to PF01346, Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal, score 2e-60
550537016951	phi X174 lysis protein; Provisional; Region: PRK02793
550537016952	HMMPfam hit to PF04102, SlyX, score 1.7e-37
550537016953	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
550537016954	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
550537016955	HMMPfam hit to PF00254, Peptidyl-prolyl cis-trans isomerase, FKBP-type, score 0.00018
550537016956	PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2.
550537016957	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
550537016958	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
550537016959	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
550537016960	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
550537016961	TrkA-N domain; Region: TrkA_N; pfam02254
550537016962	HMMPfam hit to PF02254, TrkA-N, score 1.2e-29
550537016963	HMMPfam hit to PF00999, Sodium/hydrogen exchanger, score 2.7e-76
550537016964	10 probable transmembrane helices predicted for SEN3285 by TMHMM2.0 at aa 6-25, 32-51, 56-75, 87-109, 113-135, 148-170, 180-202, 223-245, 265-287 and 294-316
550537016965	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
550537016966	HMMPfam hit to PF02525, Flavodoxin-like fold, score 7.9e-69
550537016967	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
550537016968	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537016969	Walker A/P-loop; other site
550537016970	ATP binding site [chemical binding]; other site
550537016971	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537016972	ABC transporter signature motif; other site
550537016973	Walker B; other site
550537016974	D-loop; other site
550537016975	ABC transporter; Region: ABC_tran_2; pfam12848
550537016976	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537016977	HMMPfam hit to PF00005, ABC transporter related, score 8e-48
550537016978	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016979	PS00211 ABC transporters family signature.
550537016980	HMMPfam hit to PF00005, ABC transporter related, score 5.6e-44
550537016981	PS00017 ATP/GTP-binding site motif A (P-loop).
550537016982	PS00211 ABC transporters family signature.
550537016983	putative monooxygenase; Provisional; Region: PRK11118
550537016984	HMMPfam hit to PF08803, Mono-oxygenase, YdhR, score 2.3e-71
550537016985	putative hydrolase; Provisional; Region: PRK10985
550537016986	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 5.7e-25
550537016987	PS01133 Uncharacterized protein family UPF0017 signature.
550537016988	hypothetical protein; Provisional; Region: PRK04966
550537016989	HMMPfam hit to PF06794, Protein of unknown function UPF0270, score 4e-48
550537016990	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
550537016991	active site
550537016992	HMMPfam hit to PF00485, Phosphoribulokinase/uridine kinase, score 9.9e-121
550537016993	PS00567 Phosphoribulokinase signature.
550537016994	hypothetical protein; Provisional; Region: PRK10738
550537016995	HMMPfam hit to PF02566, OsmC-like protein, score 1.8e-27
550537016996	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
550537016997	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
550537016998	ligand binding site [chemical binding]; other site
550537016999	flexible hinge region; other site
550537017000	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
550537017001	putative switch regulator; other site
550537017002	non-specific DNA interactions [nucleotide binding]; other site
550537017003	DNA binding site [nucleotide binding]
550537017004	sequence specific DNA binding site [nucleotide binding]; other site
550537017005	putative cAMP binding site [chemical binding]; other site
550537017006	HMMPfam hit to PF00027, Cyclic nucleotide-binding, score 5.7e-29
550537017007	PS00888 Cyclic nucleotide-binding domain signature 1.
550537017008	PS00889 Cyclic nucleotide-binding domain signature 2.
550537017009	HMMPfam hit to PF00325, Bacterial regulatory protein, Crp, score 5.9e-17
550537017010	PS00042 Bacterial regulatory proteins, crp family signature.
550537017011	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
550537017012	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
550537017013	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
550537017014	HMMPfam hit to PF05976, Protein of unknown function DUF893, YccS/YhfK, score 9.9e-09
550537017015	8 probable transmembrane helices predicted for SEN3294 by TMHMM2.0 at aa 21-43, 78-100, 107-129, 134-156, 411-433, 437-453, 458-477 and 487-506
550537017016	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017017	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
550537017018	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
550537017019	inhibitor-cofactor binding pocket; inhibition site
550537017020	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537017021	catalytic residue [active]
550537017022	HMMPfam hit to PF00202, Aminotransferase class-III, score 1.1e-184
550537017023	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
550537017024	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
550537017025	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
550537017026	glutamine binding [chemical binding]; other site
550537017027	catalytic triad [active]
550537017028	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 9.7e-88
550537017029	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017030	PS00442 Glutamine amidotransferases class-I active site.
550537017031	PS00678 Trp-Asp (WD) repeats signature.
550537017032	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
550537017033	cell filamentation protein Fic; Provisional; Region: PRK10347
550537017034	HMMPfam hit to PF02661, Filamentation induced by cAMP protein Fic, score 9.5e-35
550537017035	hypothetical protein; Provisional; Region: PRK10204
550537017036	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
550537017037	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
550537017038	substrate binding site [chemical binding]; other site
550537017039	HMMPfam hit to PF00160, Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, score 8e-72
550537017040	PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
550537017041	putative transporter; Provisional; Region: PRK03699
550537017042	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537017043	putative substrate translocation pore; other site
550537017044	12 probable transmembrane helices predicted for SEN3300 by TMHMM2.0 at aa 12-34, 49-66, 78-95, 99-121, 134-156, 161-183, 204-226, 246-268, 273-292, 297-319, 332-354 and 359-381
550537017045	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 8.8e-18
550537017046	PS00217 Sugar transport proteins signature 2.
550537017047	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017048	nitrite reductase subunit NirD; Provisional; Region: PRK14989
550537017049	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537017050	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
550537017051	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
550537017052	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
550537017053	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 7.1e-52
550537017054	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 9.5e-30
550537017055	HMMPfam hit to PF04324, BFD-like [2Fe-2S]-binding region, score 1.5e-24
550537017056	HMMPfam hit to PF03460, Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like, score 1.3e-19
550537017057	HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S region, score 1.4e-47
550537017058	PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site.
550537017059	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
550537017060	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537017061	nitrite transporter NirC; Provisional; Region: PRK11562
550537017062	HMMPfam hit to PF01226, Formate/nitrite transporter, score 8.1e-139
550537017063	6 probable transmembrane helices predicted for SEN3303 by TMHMM2.0 at aa 26-48, 58-80, 101-123, 150-172, 184-206 and 226-248
550537017064	PS01005 Formate and nitrite transporters signature 1.
550537017065	PS01006 Formate and nitrite transporters signature 2.
550537017066	siroheme synthase; Provisional; Region: cysG; PRK10637
550537017067	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
550537017068	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
550537017069	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
550537017070	active site
550537017071	SAM binding site [chemical binding]; other site
550537017072	homodimer interface [polypeptide binding]; other site
550537017073	HMMPfam hit to PF00590, Tetrapyrrole methylase, score 1.2e-99
550537017074	PS00839 Uroporphyrin-III C-methyltransferase signature 1.
550537017075	PS00840 Uroporphyrin-III C-methyltransferase signature 2.
550537017076	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017077	Autotransporter beta-domain; Region: Autotransporter; pfam03797
550537017078	HMMPfam hit to PF03797, Autotransporter beta-domain, score 7.4e-36
550537017079	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
550537017080	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017081	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
550537017082	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
550537017083	active site
550537017084	HIGH motif; other site
550537017085	dimer interface [polypeptide binding]; other site
550537017086	KMSKS motif; other site
550537017087	HMMPfam hit to PF00579, Aminoacyl-tRNA synthetase, class Ib, score 6.7e-132
550537017088	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537017089	phosphoglycolate phosphatase; Provisional; Region: PRK13222
550537017090	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537017091	motif II; other site
550537017092	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.7e-44
550537017093	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
550537017094	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
550537017095	substrate binding site [chemical binding]; other site
550537017096	hexamer interface [polypeptide binding]; other site
550537017097	metal binding site [ion binding]; metal-binding site
550537017098	HMMPfam hit to PF00834, Ribulose-phosphate 3-epimerase, score 7e-143
550537017099	PS01086 Ribulose-phosphate 3-epimerase family signature 2.
550537017100	PS01085 Ribulose-phosphate 3-epimerase family signature 1.
550537017101	DNA adenine methylase; Provisional; Region: PRK10904
550537017102	HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA methyltransferase, score 3.2e-100
550537017103	PS00092 N-6 Adenine-specific DNA methylases signature.
550537017104	cell division protein DamX; Validated; Region: PRK10905
550537017105	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
550537017106	HMMPfam hit to PF05036, Sporulation/cell division region, bacteria, score 9e-17
550537017107	1 probable transmembrane helix predicted for SEN3311 by TMHMM2.0 at aa 93-115
550537017108	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
550537017109	active site
550537017110	dimer interface [polypeptide binding]; other site
550537017111	metal binding site [ion binding]; metal-binding site
550537017112	HMMPfam hit to PF01761, 3-dehydroquinate synthase AroB, score 1.8e-180
550537017113	shikimate kinase; Reviewed; Region: aroK; PRK00131
550537017114	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
550537017115	ADP binding site [chemical binding]; other site
550537017116	magnesium binding site [ion binding]; other site
550537017117	putative shikimate binding site; other site
550537017118	HMMPfam hit to PF01202, Shikimate kinase, score 2.4e-81
550537017119	PS01128 Shikimate kinase signature.
550537017120	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017121	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
550537017122	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
550537017123	HMMPfam hit to PF00263, Bacterial type II and III secretion system protein, score 4.6e-87
550537017124	PS00875 Bacterial type II secretion system protein D signature.
550537017125	HMMPfam hit to PF03958, NolW-like, score 1.1e-11
550537017126	HMMPfam hit to PF07660, Secretin/TonB, short N-terminal, score 3.8e-07
550537017127	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
550537017128	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017129	1 probable transmembrane helix predicted for SEN3316 by TMHMM2.0 at aa 15-37
550537017130	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
550537017131	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
550537017132	HMMPfam hit to PF05137, Fimbrial assembly, score 3.1e-16
550537017133	1 probable transmembrane helix predicted for SEN3317 by TMHMM2.0 at aa 21-43
550537017134	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
550537017135	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
550537017136	Transglycosylase; Region: Transgly; pfam00912
550537017137	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
550537017138	1 probable transmembrane helix predicted for SEN3319 by TMHMM2.0 at aa 12-34
550537017139	HMMPfam hit to PF00912, Glycosyl transferase, family 51, score 8.7e-94
550537017140	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017141	HMMPfam hit to PF00905, Penicillin-binding protein, transpeptidase, score 2.8e-25
550537017142	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
550537017143	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
550537017144	ADP-ribose binding site [chemical binding]; other site
550537017145	dimer interface [polypeptide binding]; other site
550537017146	active site
550537017147	nudix motif; other site
550537017148	metal binding site [ion binding]; metal-binding site
550537017149	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 1.2e-15
550537017150	PS00893 mutT domain signature.
550537017151	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
550537017152	HMMPfam hit to PF07095, Intracellular growth attenuator IgaA, score 0
550537017153	5 probable transmembrane helices predicted for SEN3321 by TMHMM2.0 at aa 4-22, 202-221, 225-247, 336-358 and 652-674
550537017154	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017155	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
550537017156	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537017157	motif II; other site
550537017158	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 7.8e-24
550537017159	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537017160	RNA binding surface [nucleotide binding]; other site
550537017161	HMMPfam hit to PF01479, RNA-binding S4, score 1.6e-12
550537017162	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
550537017163	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
550537017164	dimerization interface [polypeptide binding]; other site
550537017165	domain crossover interface; other site
550537017166	redox-dependent activation switch; other site
550537017167	HMMPfam hit to PF01430, Hsp33 protein, score 8.4e-145
550537017168	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
550537017169	11 probable transmembrane helices predicted for SEN3325 by TMHMM2.0 at aa 12-34, 39-61, 66-84, 99-118, 138-160, 183-200, 213-235, 250-268, 281-303, 318-340 and 353-375
550537017170	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
550537017171	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
550537017172	active site
550537017173	substrate-binding site [chemical binding]; other site
550537017174	metal-binding site [ion binding]
550537017175	ATP binding site [chemical binding]; other site
550537017176	HMMPfam hit to PF01293, Phosphoenolpyruvate carboxykinase, ATP-utilising, score 0
550537017177	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017178	PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature.
550537017179	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
550537017180	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537017181	dimerization interface [polypeptide binding]; other site
550537017182	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537017183	dimer interface [polypeptide binding]; other site
550537017184	phosphorylation site [posttranslational modification]
550537017185	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537017186	ATP binding site [chemical binding]; other site
550537017187	G-X-G motif; other site
550537017188	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 4.3e-34
550537017189	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 8.3e-14
550537017190	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1.3e-10
550537017191	1 probable transmembrane helix predicted for SEN3327 by TMHMM2.0 at aa 121-140
550537017192	osmolarity response regulator; Provisional; Region: ompR; PRK09468
550537017193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537017194	active site
550537017195	phosphorylation site [posttranslational modification]
550537017196	intermolecular recognition site; other site
550537017197	dimerization interface [polypeptide binding]; other site
550537017198	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537017199	DNA binding site [nucleotide binding]
550537017200	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 4.3e-20
550537017201	HMMPfam hit to PF00072, Response regulator receiver, score 5.9e-44
550537017202	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
550537017203	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
550537017204	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
550537017205	HMMPfam hit to PF03449, Transcription elongation factor, GreA/GreB region, prokaryotic, score 1e-43
550537017206	PS00829 Prokaryotic transcription elongation factors signature 1.
550537017207	HMMPfam hit to PF01272, Transcription elongation factor, GreA/GreB region, prokaryotic, score 5.3e-43
550537017208	PS00830 Prokaryotic transcription elongation factors signature 2.
550537017209	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
550537017210	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
550537017211	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
550537017212	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
550537017213	RNA binding site [nucleotide binding]; other site
550537017214	HMMPfam hit to PF00575, S1, RNA binding, score 2e-28
550537017215	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
550537017216	HMMPfam hit to PF04023, Ferrous iron transporter, FeoA subunit, score 2.1e-08
550537017217	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
550537017218	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
550537017219	G1 box; other site
550537017220	GTP/Mg2+ binding site [chemical binding]; other site
550537017221	Switch I region; other site
550537017222	G2 box; other site
550537017223	G3 box; other site
550537017224	Switch II region; other site
550537017225	G4 box; other site
550537017226	G5 box; other site
550537017227	Nucleoside recognition; Region: Gate; pfam07670
550537017228	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
550537017229	Nucleoside recognition; Region: Gate; pfam07670
550537017230	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 1.2e-38
550537017231	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017232	HMMPfam hit to PF02421, Ferrous iron transport protein B, N-terminal, score 3.9e-44
550537017233	10 probable transmembrane helices predicted for SEN3332 by TMHMM2.0 at aa 277-299, 309-331, 344-366, 386-408, 429-447, 451-473, 510-532, 663-685, 692-714 and 720-742
550537017234	HMMPfam hit to PF07670, Nucleoside recognition, score 3.1e-16
550537017235	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017236	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017237	HMMPfam hit to PF07664, Ferrous iron transport B, C-terminal, score 4.7e-23
550537017238	HMMPfam hit to PF07670, Nucleoside recognition, score 3.1e-18
550537017239	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
550537017240	HMMPfam hit to PF09012, Protein of unknown function DUF1920, score 2e-56
550537017241	hypothetical protein; Provisional; Region: PRK09956
550537017242	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
550537017243	HMMPfam hit to PF04754, Transposase (), YhgA-like, score 1.8e-211
550537017244	carboxylesterase BioH; Provisional; Region: PRK10349
550537017245	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
550537017246	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 4.6e-33
550537017247	DNA utilization protein GntX; Provisional; Region: PRK11595
550537017248	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537017249	active site
550537017250	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
550537017251	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 7.5e-07
550537017252	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
550537017253	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
550537017254	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
550537017255	HMMPfam hit to PF01521, HesB/YadR/YfhF, score 4.8e-35
550537017256	HMMPfam hit to PF01106, NIF system FeS cluster assembly, NifU, C-terminal, score 9.2e-07
550537017257	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017258	high-affinity gluconate transporter; Provisional; Region: PRK14984
550537017259	gluconate transporter; Region: gntP; TIGR00791
550537017260	HMMPfam hit to PF02447, Gluconate transporter, score 4.9e-272
550537017261	10 probable transmembrane helices predicted for SEN3338 by TMHMM2.0 at aa 7-27, 37-59, 80-98, 103-125, 159-181, 242-264, 277-296, 333-355, 362-384 and 399-421
550537017262	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017263	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
550537017264	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
550537017265	HMMPfam hit to PF02446, Glycoside hydrolase, family 77, score 5e-259
550537017266	maltodextrin phosphorylase; Provisional; Region: PRK14985
550537017267	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
550537017268	homodimer interface [polypeptide binding]; other site
550537017269	active site pocket [active]
550537017270	HMMPfam hit to PF00343, Glycosyl transferase, family 35, score 0
550537017271	PS00102 Phosphorylase pyridoxal-phosphate attachment site.
550537017272	transcriptional regulator MalT; Provisional; Region: PRK04841
550537017273	AAA ATPase domain; Region: AAA_16; pfam13191
550537017274	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537017275	DNA binding residues [nucleotide binding]
550537017276	dimerization interface [polypeptide binding]; other site
550537017277	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 3.4e-24
550537017278	PS00622 Bacterial regulatory proteins, luxR family signature.
550537017279	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
550537017280	HMMPfam hit to PF05016, Plasmid stabilization system, score 1.4e-09
550537017281	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
550537017282	HMMPfam hit to PF04221, RelB antitoxin, score 3.8e-35
550537017283	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
550537017284	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
550537017285	putative active site [active]
550537017286	adenylation catalytic residue [active]
550537017287	HMMPfam hit to PF01137, RNA 3'-terminal phosphate cyclase, score 6e-131
550537017288	HMMPfam hit to PF05189, RNA 3'-terminal phosphate cyclase, insert region, score 4.5e-08
550537017289	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
550537017290	hypothetical protein; Reviewed; Region: PRK09588
550537017291	HMMPfam hit to PF01139, Protein of unknown function UPF0027, score 1.7e-197
550537017292	PS01288 Uncharacterized protein family UPF0027 signature.
550537017293	TROVE domain; Region: TROVE; pfam05731
550537017294	HMMPfam hit to PF05731, TROVE, score 6.7e-119
550537017295	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017296	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
550537017297	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
550537017298	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537017299	Walker A motif; other site
550537017300	ATP binding site [chemical binding]; other site
550537017301	Walker B motif; other site
550537017302	arginine finger; other site
550537017303	HMMPfam hit to PF06956, Regulator of RNA terminal phosphate cyclase, score 2.7e-132
550537017304	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 2.1e-66
550537017305	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017306	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537017307	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
550537017308	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
550537017309	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537017310	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 1.1e-84
550537017311	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 5.2e-31
550537017312	PS00894 Bacterial regulatory proteins, deoR family signature.
550537017313	intramembrane serine protease GlpG; Provisional; Region: PRK10907
550537017314	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
550537017315	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
550537017316	HMMPfam hit to PF01694, Peptidase S54, rhomboid, score 9.6e-46
550537017317	6 probable transmembrane helices predicted for SEN3349 by TMHMM2.0 at aa 98-120, 140-162, 169-188, 192-214, 223-245 and 250-272
550537017318	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017319	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
550537017320	active site residue [active]
550537017321	HMMPfam hit to PF00581, Rhodanese-like, score 2.5e-20
550537017322	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
550537017323	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 4.7e-71
550537017324	PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1.
550537017325	PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2.
550537017326	hypothetical protein; Provisional; Region: PRK09781
550537017327	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
550537017328	5 probable transmembrane helices predicted for SEN3353 by TMHMM2.0 at aa 25-56, 71-93, 106-125, 158-180 and 193-215
550537017329	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
550537017330	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
550537017331	dimer interface [polypeptide binding]; other site
550537017332	active site
550537017333	metal binding site [ion binding]; metal-binding site
550537017334	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 5.2e-55
550537017335	PS00060 Iron-containing alcohol dehydrogenases signature 2.
550537017336	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537017337	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537017338	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537017339	D-galactonate transporter; Region: 2A0114; TIGR00893
550537017340	putative substrate translocation pore; other site
550537017341	12 probable transmembrane helices predicted for SEN3354A by TMHMM2.0 at aa 21-43, 53-75, 88-107, 112-134, 147-169, 179-196, 242-264, 274-296, 308-327, 331-353, 366-388 and 398-420
550537017342	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.5e-69
550537017343	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
550537017344	HMMPfam hit to PF00920, Dihydroxy-acid and 6-phosphogluconate dehydratase, score 2.7e-206
550537017345	PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.
550537017346	PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2.
550537017347	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
550537017348	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
550537017349	inhibitor site; inhibition site
550537017350	active site
550537017351	dimer interface [polypeptide binding]; other site
550537017352	catalytic residue [active]
550537017353	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase, score 3.6e-75
550537017354	PS00666 Dihydrodipicolinate synthetase signature 2.
550537017355	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
550537017356	Transcriptional regulator [Transcription]; Region: IclR; COG1414
550537017357	Bacterial transcriptional regulator; Region: IclR; pfam01614
550537017358	HMMPfam hit to PF01614, Transcriptional regulator IclR, C-terminal, score 1.6e-41
550537017359	PS01051 Bacterial regulatory proteins, iclR family signature.
550537017360	HMMPfam hit to PF09339, Transcriptional regulator IclR, N-terminal, score 8.8e-27
550537017361	glycogen phosphorylase; Provisional; Region: PRK14986
550537017362	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
550537017363	homodimer interface [polypeptide binding]; other site
550537017364	active site pocket [active]
550537017365	HMMPfam hit to PF00343, Glycosyl transferase, family 35, score 0
550537017366	PS00102 Phosphorylase pyridoxal-phosphate attachment site.
550537017367	glycogen synthase; Provisional; Region: glgA; PRK00654
550537017368	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
550537017369	ADP-binding pocket [chemical binding]; other site
550537017370	homodimer interface [polypeptide binding]; other site
550537017371	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 9.2e-10
550537017372	HMMPfam hit to PF08323, Starch synthase catalytic region, score 1.2e-126
550537017373	PS00589 PTS HPR component serine phosphorylation site signature.
550537017374	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
550537017375	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
550537017376	ligand binding site; other site
550537017377	oligomer interface; other site
550537017378	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
550537017379	dimer interface [polypeptide binding]; other site
550537017380	N-terminal domain interface [polypeptide binding]; other site
550537017381	sulfate 1 binding site; other site
550537017382	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017383	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.2e-104
550537017384	PS00810 ADP-glucose pyrophosphorylase signature 3.
550537017385	PS00809 ADP-glucose pyrophosphorylase signature 2.
550537017386	PS00808 ADP-glucose pyrophosphorylase signature 1.
550537017387	glycogen debranching enzyme; Provisional; Region: PRK03705
550537017388	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
550537017389	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
550537017390	active site
550537017391	catalytic site [active]
550537017392	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 3.2e-11
550537017393	HMMPfam hit to PF02922, Glycoside hydrolase, family 13, N-terminal, score 1.7e-30
550537017394	glycogen branching enzyme; Provisional; Region: PRK05402
550537017395	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
550537017396	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
550537017397	active site
550537017398	catalytic site [active]
550537017399	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
550537017400	HMMPfam hit to PF02806, Alpha-amylase, C-terminal all beta, score 6.9e-40
550537017401	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 6.8e-12
550537017402	HMMPfam hit to PF02922, Glycoside hydrolase, family 13, N-terminal, score 6.9e-39
550537017403	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
550537017404	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
550537017405	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisation region, score 1.3e-84
550537017406	PS01103 Aspartate-semialdehyde dehydrogenase signature.
550537017407	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD - binding, score 1.8e-36
550537017408	low affinity gluconate transporter; Provisional; Region: PRK10472
550537017409	gluconate transporter; Region: gntP; TIGR00791
550537017410	13 probable transmembrane helices predicted for SEN3364 by TMHMM2.0 at aa 4-21, 28-47, 57-79, 104-126, 146-168, 175-197, 228-250, 262-284, 299-321, 328-350, 354-373, 386-408 and 423-445
550537017411	HMMPfam hit to PF02447, Gluconate transporter, score 1.1e-257
550537017412	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017413	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
550537017414	ATP-binding site [chemical binding]; other site
550537017415	Gluconate-6-phosphate binding site [chemical binding]; other site
550537017416	HMMPfam hit to PF01202, Shikimate kinase, score 2.1e-07
550537017417	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017418	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
550537017419	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537017420	DNA binding site [nucleotide binding]
550537017421	domain linker motif; other site
550537017422	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
550537017423	putative ligand binding site [chemical binding]; other site
550537017424	putative dimerization interface [polypeptide binding]; other site
550537017425	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 3.1e-24
550537017426	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 3.8e-10
550537017427	PS00356 Bacterial regulatory proteins, lacI family signature.
550537017428	Pirin-related protein [General function prediction only]; Region: COG1741
550537017429	Pirin; Region: Pirin; pfam02678
550537017430	HMMPfam hit to PF02678, Pirin, N-terminal, score 1.9e-65
550537017431	putative oxidoreductase; Provisional; Region: PRK10206
550537017432	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
550537017433	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
550537017434	HMMPfam hit to PF02894, Oxidoreductase, C-terminal, score 2.3e-19
550537017435	HMMPfam hit to PF01408, Oxidoreductase, N-terminal, score 1.3e-33
550537017436	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017437	1 probable transmembrane helix predicted for SEN3368A by TMHMM2.0 at aa 7-29
550537017438	putative acetyltransferase YhhY; Provisional; Region: PRK10140
550537017439	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537017440	Coenzyme A binding pocket [chemical binding]; other site
550537017441	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 2.5e-20
550537017442	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537017443	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537017444	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537017445	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
550537017446	substrate binding site [chemical binding]; other site
550537017447	dimer interface [polypeptide binding]; other site
550537017448	ATP binding site [chemical binding]; other site
550537017449	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 7.3e-15
550537017450	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 7.3e-78
550537017451	PS00584 pfkB family of carbohydrate kinases signature 2.
550537017452	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
550537017453	HMMPfam hit to PF07090, Protein of unknown function DUF1355, score 1.1e-177
550537017454	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017455	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
550537017456	Protein of unknown function, DUF606; Region: DUF606; pfam04657
550537017457	10 probable transmembrane helices predicted for SEN3372 by TMHMM2.0 at aa 7-26, 41-60, 80-97, 102-124, 137-156, 166-188, 201-223, 233-252, 257-276 and 286-308
550537017458	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
550537017459	active site
550537017460	substrate binding pocket [chemical binding]; other site
550537017461	homodimer interaction site [polypeptide binding]; other site
550537017462	HMMPfam hit to PF02126, Aryldialkylphosphatase, score 7.1e-37
550537017463	PS01322 Phosphotriesterase family signature 1.
550537017464	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
550537017465	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
550537017466	HMMPfam hit to PF01019, Gamma-glutamyltranspeptidase, score 2.2e-279
550537017467	PS00462 Gamma-glutamyltranspeptidase signature.
550537017468	hypothetical protein; Provisional; Region: PRK10350
550537017469	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
550537017470	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
550537017471	putative active site [active]
550537017472	catalytic site [active]
550537017473	putative metal binding site [ion binding]; other site
550537017474	HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 2.6e-67
550537017475	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
550537017476	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
550537017477	Walker A/P-loop; other site
550537017478	ATP binding site [chemical binding]; other site
550537017479	Q-loop/lid; other site
550537017480	ABC transporter signature motif; other site
550537017481	Walker B; other site
550537017482	D-loop; other site
550537017483	H-loop/switch region; other site
550537017484	TOBE domain; Region: TOBE_2; pfam08402
550537017485	HMMPfam hit to PF08402, Transport-associated OB, type 2, score 4.3e-12
550537017486	HMMPfam hit to PF00005, ABC transporter related, score 2.1e-60
550537017487	PS00211 ABC transporters family signature.
550537017488	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017489	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
550537017490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537017491	dimer interface [polypeptide binding]; other site
550537017492	conserved gate region; other site
550537017493	ABC-ATPase subunit interface; other site
550537017494	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 9.2e-29
550537017495	7 probable transmembrane helices predicted for SEN3378 by TMHMM2.0 at aa 7-29, 82-104, 111-130, 145-167, 188-210, 215-237 and 250-272
550537017496	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537017497	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
550537017498	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537017499	dimer interface [polypeptide binding]; other site
550537017500	conserved gate region; other site
550537017501	putative PBP binding loops; other site
550537017502	ABC-ATPase subunit interface; other site
550537017503	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 7.2e-19
550537017504	6 probable transmembrane helices predicted for SEN3379 by TMHMM2.0 at aa 12-34, 71-93, 106-128, 157-179, 206-228 and 266-288
550537017505	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537017506	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
550537017507	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
550537017508	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 3.1e-34
550537017509	PS01037 Bacterial extracellular solute-binding proteins, family 1 signature.
550537017510	1 probable transmembrane helix predicted for SEN3380 by TMHMM2.0 at aa 7-29
550537017511	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
550537017512	HMMPfam hit to PF05012, Death-on-curing protein, score 7.2e-38
550537017513	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
550537017514	HMMPfam hit to PF02604, Protein of unknown function DUF172, score 1.6e-11
550537017515	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
550537017516	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
550537017517	Walker A/P-loop; other site
550537017518	ATP binding site [chemical binding]; other site
550537017519	Q-loop/lid; other site
550537017520	ABC transporter signature motif; other site
550537017521	Walker B; other site
550537017522	D-loop; other site
550537017523	H-loop/switch region; other site
550537017524	HMMPfam hit to PF00005, ABC transporter related, score 9e-57
550537017525	PS00211 ABC transporters family signature.
550537017526	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017527	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
550537017528	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
550537017529	Walker A/P-loop; other site
550537017530	ATP binding site [chemical binding]; other site
550537017531	Q-loop/lid; other site
550537017532	ABC transporter signature motif; other site
550537017533	Walker B; other site
550537017534	D-loop; other site
550537017535	H-loop/switch region; other site
550537017536	HMMPfam hit to PF00005, ABC transporter related, score 6.2e-55
550537017537	PS00211 ABC transporters family signature.
550537017538	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017539	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
550537017540	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
550537017541	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
550537017542	TM-ABC transporter signature motif; other site
550537017543	10 probable transmembrane helices predicted for SEN3385 by TMHMM2.0 at aa 4-26, 47-66, 91-108, 120-142, 162-184, 193-210, 261-283, 315-337, 352-374 and 381-400
550537017544	HMMPfam hit to PF02653, Bacterial inner-membrane translocator, score 4.3e-73
550537017545	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
550537017546	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
550537017547	TM-ABC transporter signature motif; other site
550537017548	8 probable transmembrane helices predicted for SEN3386 by TMHMM2.0 at aa 15-37, 44-66, 70-92, 105-124, 153-175, 207-229, 244-266 and 282-301
550537017549	HMMPfam hit to PF02653, Bacterial inner-membrane translocator, score 2.4e-70
550537017550	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
550537017551	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
550537017552	dimerization interface [polypeptide binding]; other site
550537017553	ligand binding site [chemical binding]; other site
550537017554	HMMPfam hit to PF01094, Extracellular ligand-binding receptor, score 7.2e-73
550537017555	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
550537017556	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 9.8e-05
550537017557	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
550537017558	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
550537017559	dimerization interface [polypeptide binding]; other site
550537017560	ligand binding site [chemical binding]; other site
550537017561	HMMPfam hit to PF01094, Extracellular ligand-binding receptor, score 1.8e-71
550537017562	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
550537017563	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
550537017564	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
550537017565	DNA binding residues [nucleotide binding]
550537017566	HMMPfam hit to PF04545, RNA polymerase sigma-70 region 4, score 1.2e-20
550537017567	PS00716 Sigma-70 factors family signature 2.
550537017568	HMMPfam hit to PF04542, RNA polymerase sigma-70 region 2, score 5.3e-22
550537017569	PS00715 Sigma-70 factors family signature 1.
550537017570	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
550537017571	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
550537017572	HMMPfam hit to PF02687, Protein of unknown function DUF214, permase predicted, score 3.2e-23
550537017573	4 probable transmembrane helices predicted for SEN3392 by TMHMM2.0 at aa 71-93, 223-245, 266-288 and 323-342
550537017574	cell division protein FtsE; Provisional; Region: PRK10908
550537017575	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537017576	Walker A/P-loop; other site
550537017577	ATP binding site [chemical binding]; other site
550537017578	Q-loop/lid; other site
550537017579	ABC transporter signature motif; other site
550537017580	Walker B; other site
550537017581	D-loop; other site
550537017582	H-loop/switch region; other site
550537017583	HMMPfam hit to PF00005, ABC transporter related, score 5.8e-75
550537017584	PS00211 ABC transporters family signature.
550537017585	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017586	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
550537017587	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
550537017588	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
550537017589	P loop; other site
550537017590	GTP binding site [chemical binding]; other site
550537017591	HMMPfam hit to PF00448, Signal recognition particle, SRP54 subunit, GTPase, score 1.3e-127
550537017592	PS00300 SRP54-type proteins GTP-binding domain signature.
550537017593	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017594	HMMPfam hit to PF02881, Signal recognition particle, SRP54 subunit, helical bundle, score 1.3e-19
550537017595	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
550537017596	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537017597	S-adenosylmethionine binding site [chemical binding]; other site
550537017598	HMMPfam hit to PF03602, Conserved hypothetical protein CHP00095, score 5.8e-92
550537017599	PS00092 N-6 Adenine-specific DNA methylases signature.
550537017600	hypothetical protein; Provisional; Region: PRK10910
550537017601	HMMPfam hit to PF06611, Protein of unknown function DUF1145, score 1.1e-38
550537017602	2 probable transmembrane helices predicted for SEN3396 by TMHMM2.0 at aa 4-23 and 30-52
550537017603	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
550537017604	Predicted membrane protein [Function unknown]; Region: COG3714
550537017605	HMMPfam hit to PF07947, YhhN-like, score 6.2e-61
550537017606	6 probable transmembrane helices predicted for SEN3398 by TMHMM2.0 at aa 28-45, 50-72, 77-96, 101-123, 130-152 and 156-178
550537017607	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
550537017608	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
550537017609	metal-binding site [ion binding]
550537017610	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
550537017611	HMMPfam hit to PF00403, Heavy metal transport/detoxification protein, score 5.7e-13
550537017612	PS01047 Heavy-metal-associated domain.
550537017613	5 probable transmembrane helices predicted for SEN3399 by TMHMM2.0 at aa 147-169, 189-211, 350-372, 387-409 and 690-712
550537017614	HMMPfam hit to PF00122, E1-E2 ATPase-associated region, score 8.5e-97
550537017615	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537017616	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537017617	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.7e-30
550537017618	PS00154 E1-E2 ATPases phosphorylation site.
550537017619	PS01229 Hypothetical cof family signature 2.
550537017620	PS00141 Eukaryotic and viral aspartyl proteases active site.
550537017621	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
550537017622	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
550537017623	dimer interface [polypeptide binding]; other site
550537017624	ligand binding site [chemical binding]; other site
550537017625	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537017626	dimerization interface [polypeptide binding]; other site
550537017627	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537017628	dimer interface [polypeptide binding]; other site
550537017629	putative CheW interface [polypeptide binding]; other site
550537017630	2 probable transmembrane helices predicted for SEN3400 by TMHMM2.0 at aa 10-32 and 195-217
550537017631	HMMPfam hit to PF02203, Ligand binding Tar, score 9.9e-60
550537017632	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 4.8e-19
550537017633	PS00538 Bacterial chemotaxis sensory transducers signature.
550537017634	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 2.1e-121
550537017635	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
550537017636	CPxP  motif; other site
550537017637	HMMPfam hit to PF01206, SirA-like, score 4.9e-42
550537017638	PS01148 Uncharacterized protein family UPF0033 signature.
550537017639	hypothetical protein; Provisional; Region: PRK11212
550537017640	6 probable transmembrane helices predicted for SEN3402 by TMHMM2.0 at aa 13-35, 45-64, 71-93, 108-130, 142-164 and 179-201
550537017641	HMMPfam hit to PF02592, Protein of unknown function DUF165, score 1.8e-74
550537017642	hypothetical protein; Provisional; Region: PRK11615
550537017643	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017644	major facilitator superfamily transporter; Provisional; Region: PRK05122
550537017645	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537017646	putative substrate translocation pore; other site
550537017647	12 probable transmembrane helices predicted for SEN3404 by TMHMM2.0 at aa 19-41, 51-73, 85-107, 122-144, 151-173, 177-199, 220-242, 252-271, 278-300, 310-332, 339-361 and 366-388
550537017648	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.3e-22
550537017649	Domain of unknown function DUF20; Region: UPF0118; pfam01594
550537017650	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
550537017651	HMMPfam hit to PF01594, Protein of unknown function UPF0118, score 2.1e-93
550537017652	8 probable transmembrane helices predicted for SEN3405 by TMHMM2.0 at aa 13-35, 39-56, 63-85, 141-163, 192-214, 224-246, 253-275 and 295-317
550537017653	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
550537017654	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
550537017655	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase, score 0.00043
550537017656	nickel responsive regulator; Provisional; Region: PRK02967
550537017657	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
550537017658	HMMPfam hit to PF01402, CopG-like DNA-binding, score 6.7e-13
550537017659	HMMPfam hit to PF08753, NikR C terminal nickel binding, score 7.8e-41
550537017660	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
550537017661	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
550537017662	6 probable transmembrane helices predicted for SEN3408 by TMHMM2.0 at aa 25-47, 174-196, 230-252, 256-278, 285-302 and 344-366
550537017663	HMMPfam hit to PF01061, ABC-2 type transporter, score 9e-31
550537017664	PS00890 ABC-2 type transport system integral membrane proteins signature.
550537017665	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
550537017666	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
550537017667	Walker A/P-loop; other site
550537017668	ATP binding site [chemical binding]; other site
550537017669	Q-loop/lid; other site
550537017670	ABC transporter signature motif; other site
550537017671	Walker B; other site
550537017672	D-loop; other site
550537017673	H-loop/switch region; other site
550537017674	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
550537017675	Walker A/P-loop; other site
550537017676	ATP binding site [chemical binding]; other site
550537017677	Q-loop/lid; other site
550537017678	ABC transporter signature motif; other site
550537017679	Walker B; other site
550537017680	D-loop; other site
550537017681	H-loop/switch region; other site
550537017682	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
550537017683	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
550537017684	5 probable transmembrane helices predicted for SEN3409 by TMHMM2.0 at aa 560-582, 716-738, 771-793, 800-822 and 886-908
550537017685	HMMPfam hit to PF01061, ABC-2 type transporter, score 2.4e-14
550537017686	HMMPfam hit to PF00005, ABC transporter related, score 8.6e-48
550537017687	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017688	HMMPfam hit to PF00005, ABC transporter related, score 5.4e-45
550537017689	PS00211 ABC transporters family signature.
550537017690	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017691	HlyD family secretion protein; Region: HlyD; pfam00529
550537017692	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537017693	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537017694	HMMPfam hit to PF00529, Secretion protein HlyD, score 1.2e-39
550537017695	1 probable transmembrane helix predicted for SEN3410 by TMHMM2.0 at aa 7-26
550537017696	Predicted flavoproteins [General function prediction only]; Region: COG2081
550537017697	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537017698	HMMPfam hit to PF03486, HI0933-like protein, score 1.1e-249
550537017699	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
550537017700	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
550537017701	HMMPfam hit to PF01384, Phosphate transporter, score 1.1e-115
550537017702	8 probable transmembrane helices predicted for SEN3412 by TMHMM2.0 at aa 13-35, 53-75, 82-104, 114-136, 166-183, 193-215, 339-361 and 431-453
550537017703	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537017704	universal stress protein UspB; Provisional; Region: PRK04960
550537017705	2 probable transmembrane helices predicted for SEN3413 by TMHMM2.0 at aa 5-24 and 90-109
550537017706	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
550537017707	Ligand Binding Site [chemical binding]; other site
550537017708	HMMPfam hit to PF00582, UspA, score 6e-17
550537017709	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
550537017710	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537017711	putative substrate translocation pore; other site
550537017712	POT family; Region: PTR2; pfam00854
550537017713	14 probable transmembrane helices predicted for SEN3415 by TMHMM2.0 at aa 20-42, 52-74, 83-102, 107-124, 145-167, 171-193, 214-233, 237-255, 268-290, 314-336, 349-371, 386-408, 415-437 and 457-479
550537017714	HMMPfam hit to PF00854, TGF-beta receptor, type I/II extracellular region, score 7.7e-110
550537017715	PS01023 PTR2 family proton/oligopeptide symporters signature 2.
550537017716	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537017717	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537017718	S-adenosylmethionine binding site [chemical binding]; other site
550537017719	HMMPfam hit to PF04445, Protein of unknown function DUF548, score 2.8e-171
550537017720	oligopeptidase A; Provisional; Region: PRK10911
550537017721	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
550537017722	active site
550537017723	Zn binding site [ion binding]; other site
550537017724	HMMPfam hit to PF01432, Peptidase M3A and M3B, thimet/oligopeptidase F, score 5.8e-246
550537017725	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537017726	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
550537017727	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
550537017728	active site
550537017729	HMMPfam hit to PF01569, Phosphatidic acid phosphatase type 2-like, score 2.1e-09
550537017730	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
550537017731	HMMPfam hit to PF04378, Protein of unknown function DUF519, score 1.3e-169
550537017732	PS00092 N-6 Adenine-specific DNA methylases signature.
550537017733	PS00092 N-6 Adenine-specific DNA methylases signature.
550537017734	glutathione reductase; Validated; Region: PRK06116
550537017735	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
550537017736	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537017737	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
550537017738	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 2e-68
550537017739	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
550537017740	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 5e-32
550537017741	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase dimerisation region, score 3.1e-53
550537017742	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
550537017743	active site
550537017744	homodimer interface [polypeptide binding]; other site
550537017745	homotetramer interface [polypeptide binding]; other site
550537017746	HMMPfam hit to PF00710, Asparaginase/glutaminase, score 4.3e-133
550537017747	PS00917 Asparaginase / glutaminase active site signature 2.
550537017748	PS00144 Asparaginase / glutaminase active site signature 1.
550537017749	1 probable transmembrane helix predicted for SEN3421 by TMHMM2.0 at aa 7-29
550537017750	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
550537017751	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
550537017752	11 probable transmembrane helices predicted for SEN3422 by TMHMM2.0 at aa 20-42, 52-74, 87-109, 163-185, 227-249, 264-281, 294-316, 331-350, 357-374, 379-398 and 419-438
550537017753	HMMPfam hit to PF03605, Anaerobic c4-dicarboxylate membrane transporter, score 3.6e-180
550537017754	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
550537017755	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537017756	substrate binding site [chemical binding]; other site
550537017757	ATP binding site [chemical binding]; other site
550537017758	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 1.6e-08
550537017759	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017760	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
550537017761	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
550537017762	putative active site [active]
550537017763	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
550537017764	dimer interface [polypeptide binding]; other site
550537017765	active site
550537017766	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 7.9e-18
550537017767	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 1.3e-07
550537017768	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
550537017769	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537017770	DNA-binding site [nucleotide binding]; DNA binding site
550537017771	UTRA domain; Region: UTRA; pfam07702
550537017772	HMMPfam hit to PF07702, UbiC transcription regulator-associated, score 1.1e-37
550537017773	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 5.7e-28
550537017774	trehalase; Provisional; Region: treF; PRK13270
550537017775	Trehalase; Region: Trehalase; pfam01204
550537017776	HMMPfam hit to PF01204, Glycoside hydrolase, family 37, score 1.7e-252
550537017777	PS00927 Trehalase signature 1.
550537017778	PS00928 Trehalase signature 2.
550537017779	1 probable transmembrane helix predicted for SEN3427 by TMHMM2.0 at aa 337-359
550537017780	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
550537017781	catalytic residue [active]
550537017782	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
550537017783	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537017784	DNA binding residues [nucleotide binding]
550537017785	dimerization interface [polypeptide binding]; other site
550537017786	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1.5e-25
550537017787	PS00622 Bacterial regulatory proteins, luxR family signature.
550537017788	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537017789	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537017790	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
550537017791	putative effector binding pocket; other site
550537017792	putative dimerization interface [polypeptide binding]; other site
550537017793	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.1e-17
550537017794	PS00044 Bacterial regulatory proteins, lysR family signature.
550537017795	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.1e-40
550537017796	inner membrane protein YhjD; Region: TIGR00766
550537017797	HMMPfam hit to PF03631, Ribonuclease BN, score 1.8e-27
550537017798	6 probable transmembrane helices predicted for SEN3431 by TMHMM2.0 at aa 80-102, 135-157, 191-213, 233-255, 267-289 and 304-326
550537017799	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537017800	metabolite-proton symporter; Region: 2A0106; TIGR00883
550537017801	putative substrate translocation pore; other site
550537017802	HMMPfam hit to PF00083, General substrate transporter, score 3e-20
550537017803	11 probable transmembrane helices predicted for SEN3432 by TMHMM2.0 at aa 32-54, 69-88, 109-131, 166-188, 195-217, 247-269, 290-312, 322-341, 348-370, 380-402 and 409-431
550537017804	PS00359 Ribosomal protein L11 signature.
550537017805	PS00216 Sugar transport proteins signature 1.
550537017806	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
550537017807	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
550537017808	HMMPfam hit to PF05170, AsmA, score 1.2e-223
550537017809	1 probable transmembrane helix predicted for SEN3433 by TMHMM2.0 at aa 7-29
550537017810	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537017811	HMMPfam hit to PF00563, EAL, score 2.2e-40
550537017812	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537017813	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
550537017814	substrate binding site [chemical binding]; other site
550537017815	ATP binding site [chemical binding]; other site
550537017816	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 2.3e-83
550537017817	PS00584 pfkB family of carbohydrate kinases signature 2.
550537017818	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
550537017819	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
550537017820	HMMPfam hit to PF05193, Peptidase M16, C-terminal, score 3.5e-26
550537017821	HMMPfam hit to PF00675, Peptidase M16, N-terminal, score 0.024
550537017822	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537017823	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
550537017824	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
550537017825	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter, score 2.9e-211
550537017826	9 probable transmembrane helices predicted for SEN3437 by TMHMM2.0 at aa 5-27, 47-64, 77-99, 141-163, 184-206, 216-238, 289-311, 326-348 and 353-375
550537017827	PS00714 Sodium:dicarboxylate symporter family signature 2.
550537017828	PS00713 Sodium:dicarboxylate symporter family signature 1.
550537017829	putative diguanylate cyclase; Provisional; Region: PRK13561
550537017830	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537017831	metal binding site [ion binding]; metal-binding site
550537017832	active site
550537017833	I-site; other site
550537017834	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537017835	HMMPfam hit to PF00563, EAL, score 8.4e-114
550537017836	HMMPfam hit to PF00990, GGDEF, score 1e-06
550537017837	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 8.9e-08
550537017838	1 probable transmembrane helix predicted for SEN3438 by TMHMM2.0 at aa 127-149
550537017839	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
550537017840	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
550537017841	TPR motif; other site
550537017842	binding surface
550537017843	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
550537017844	TPR motif; other site
550537017845	binding surface
550537017846	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
550537017847	binding surface
550537017848	TPR motif; other site
550537017849	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
550537017850	HMMPfam hit to PF05420, Cellulose synthase operon C, C-terminal, score 7.4e-172
550537017851	HMMPfam hit to PF07721, Tetratricopeptide TPR-4, score 0.025
550537017852	HMMPfam hit to PF00515, Tetratricopeptide TPR-1, score 0.14
550537017853	HMMPfam hit to PF00515, Tetratricopeptide TPR-1, score 0.11
550537017854	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 5e-05
550537017855	Signal peptide predicted for SEN3439 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.443 between residues 46 and 47
550537017856	endo-1,4-D-glucanase; Provisional; Region: PRK11097
550537017857	HMMPfam hit to PF01270, Glycoside hydrolase, family 8, score 3.3e-144
550537017858	PS00812 Glycosyl hydrolases family 8 signature.
550537017859	1 probable transmembrane helix predicted for SEN3440 by TMHMM2.0 at aa 7-29
550537017860	cellulose synthase regulator protein; Provisional; Region: PRK11114
550537017861	2 probable transmembrane helices predicted for SEN3441 by TMHMM2.0 at aa 7-29 and 728-750
550537017862	HMMPfam hit to PF03170, Cellulose synthase, subunit B, score 3.2e-299
550537017863	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
550537017864	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
550537017865	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
550537017866	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
550537017867	DXD motif; other site
550537017868	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
550537017869	PilZ domain; Region: PilZ; pfam07238
550537017870	HMMPfam hit to PF07238, Type IV pilus assembly PilZ, score 4.1e-21
550537017871	10 probable transmembrane helices predicted for SEN3442 by TMHMM2.0 at aa 28-50, 150-169, 173-190, 197-216, 229-251, 522-541, 545-567, 588-610, 633-655 and 668-690
550537017872	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 1.1e-25
550537017873	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017874	PS00215 Mitochondrial energy transfer proteins signature.
550537017875	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017876	cell division protein; Provisional; Region: PRK10037
550537017877	HMMPfam hit to PF06564, YhjQ, score 4.4e-152
550537017878	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
550537017879	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
550537017880	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
550537017881	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
550537017882	1 probable transmembrane helix predicted for SEN3446 by TMHMM2.0 at aa 7-29
550537017883	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
550537017884	4 probable transmembrane helices predicted for SEN3447 by TMHMM2.0 at aa 33-55, 68-85, 114-133 and 140-162
550537017887	HMMPfam hit to PF01053, Cys/Met metabolism, pyridoxal phosphate-dependent enzyme, score 1.3e-21
550537017888	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
550537017889	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
550537017890	11 probable transmembrane helices predicted for SEN3449 by TMHMM2.0 at aa 29-51, 56-73, 105-127, 147-169, 176-194, 214-236, 256-278, 303-325, 351-373, 377-399 and 412-431
550537017891	PS00307 Legume lectins beta-chain signature.
550537017892	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
550537017893	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537017894	Walker A/P-loop; other site
550537017895	ATP binding site [chemical binding]; other site
550537017896	Q-loop/lid; other site
550537017897	ABC transporter signature motif; other site
550537017898	Walker B; other site
550537017899	D-loop; other site
550537017900	H-loop/switch region; other site
550537017901	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
550537017902	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 1.8e-32
550537017903	HMMPfam hit to PF00005, ABC transporter related, score 1.2e-59
550537017904	PS00211 ABC transporters family signature.
550537017905	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017906	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
550537017907	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
550537017908	Walker A/P-loop; other site
550537017909	ATP binding site [chemical binding]; other site
550537017910	Q-loop/lid; other site
550537017911	ABC transporter signature motif; other site
550537017912	Walker B; other site
550537017913	D-loop; other site
550537017914	H-loop/switch region; other site
550537017915	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
550537017916	HMMPfam hit to PF08352, Oligopeptide/dipeptide ABC transporter, C-terminal, score 1.8e-26
550537017917	HMMPfam hit to PF00005, ABC transporter related, score 5.9e-61
550537017918	PS00211 ABC transporters family signature.
550537017919	PS00017 ATP/GTP-binding site motif A (P-loop).
550537017920	dipeptide transporter; Provisional; Region: PRK10913
550537017921	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
550537017922	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537017923	dimer interface [polypeptide binding]; other site
550537017924	conserved gate region; other site
550537017925	putative PBP binding loops; other site
550537017926	ABC-ATPase subunit interface; other site
550537017927	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.4e-47
550537017928	5 probable transmembrane helices predicted for SEN3452 by TMHMM2.0 at aa 31-53, 103-125, 140-162, 210-232 and 265-287
550537017929	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
550537017930	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537017931	dimer interface [polypeptide binding]; other site
550537017932	conserved gate region; other site
550537017933	putative PBP binding loops; other site
550537017934	ABC-ATPase subunit interface; other site
550537017935	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 5.5e-55
550537017936	6 probable transmembrane helices predicted for SEN3453 by TMHMM2.0 at aa 9-31, 99-121, 134-156, 202-221, 258-280 and 309-331
550537017937	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537017938	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
550537017939	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
550537017940	peptide binding site [polypeptide binding]; other site
550537017941	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 1.1e-96
550537017942	PS01040 Bacterial extracellular solute-binding proteins, family 5 signature.
550537017943	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
550537017944	13 probable transmembrane helices predicted for SEN3455 by TMHMM2.0 at aa 20-42, 47-69, 76-98, 103-125, 132-154, 169-191, 196-218, 233-255, 287-309, 319-341, 348-370, 380-402 and 409-431
550537017945	HMMPfam hit to PF00860, Xanthine/uracil/vitamin C permease, score 8.9e-39
550537017946	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
550537017947	Transcriptional regulators [Transcription]; Region: PurR; COG1609
550537017948	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537017949	DNA binding site [nucleotide binding]
550537017950	domain linker motif; other site
550537017951	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
550537017952	putative dimerization interface [polypeptide binding]; other site
550537017953	putative ligand binding site [chemical binding]; other site
550537017954	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 5.9e-07
550537017955	PS00356 Bacterial regulatory proteins, lacI family signature.
550537017956	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 0.00028
550537017957	1 probable transmembrane helix predicted for SEN3457 by TMHMM2.0 at aa 67-89
550537017958	phosphoethanolamine transferase; Provisional; Region: PRK11560
550537017959	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
550537017960	Sulfatase; Region: Sulfatase; pfam00884
550537017961	HMMPfam hit to PF00884, Sulphatase, score 7.2e-74
550537017962	5 probable transmembrane helices predicted for SEN3458 by TMHMM2.0 at aa 12-31, 46-68, 81-103, 118-140 and 161-178
550537017963	HMMPfam hit to PF08019, Protein of unknown function DUF1705, score 9.1e-09
550537017964	fimbrial operon lpf
550537017965	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
550537017966	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 3.6e-11
550537017967	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
550537017968	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 0.0098
550537017969	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
550537017970	PapC N-terminal domain; Region: PapC_N; pfam13954
550537017971	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537017972	PapC C-terminal domain; Region: PapC_C; pfam13953
550537017973	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537017974	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537017975	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
550537017976	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537017977	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537017978	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 1.1e-27
550537017979	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 1e-71
550537017980	PS00635 Gram-negative pili assembly chaperone signature.
550537017981	1 probable transmembrane helix predicted for SEN3462 by TMHMM2.0 at aa 7-29
550537017982	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
550537017983	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 2.5e-68
550537017984	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
550537017985	HMMPfam hit to PF03797, Autotransporter beta-domain, score 5e-05
550537017986	1 probable transmembrane helix predicted for SEN3464 by TMHMM2.0 at aa 12-31
550537017987	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017988	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
550537017989	HMMPfam hit to PF03352, Methyladenine glycosylase, score 4.9e-131
550537017990	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537017991	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537017992	Coenzyme A binding pocket [chemical binding]; other site
550537017993	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 3e-16
550537017994	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
550537017995	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
550537017996	molybdopterin cofactor binding site [chemical binding]; other site
550537017997	substrate binding site [chemical binding]; other site
550537017998	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
550537017999	molybdopterin cofactor binding site; other site
550537018000	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 1.1e-29
550537018001	PS00932 Prokaryotic molybdopterin oxidoreductases signature 3.
550537018002	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018003	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 1.2e-186
550537018004	PS00490 Prokaryotic molybdopterin oxidoreductases signature 2.
550537018005	putative outer membrane lipoprotein; Provisional; Region: PRK10510
550537018006	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
550537018007	ligand binding site [chemical binding]; other site
550537018008	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018009	HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 2.9e-10
550537018010	2 probable transmembrane helices predicted for SEN3468 by TMHMM2.0 at aa 25-44 and 51-73
550537018011	HMMPfam hit to PF00691, Outer membrane protein, OmpA/MotB, C-terminal, score 5.6e-46
550537018012	PS01068 OmpA-like domain.
550537018013	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
550537018014	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
550537018015	dimerization interface [polypeptide binding]; other site
550537018016	ligand binding site [chemical binding]; other site
550537018017	NADP binding site [chemical binding]; other site
550537018018	catalytic site [active]
550537018019	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region, score 3e-38
550537018020	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding, score 2.2e-88
550537018021	PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
550537018022	PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
550537018023	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
550537018024	1 probable transmembrane helix predicted for SEN3470 by TMHMM2.0 at aa 10-27
550537018025	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018026	Predicted transcriptional regulator [Transcription]; Region: COG2944
550537018027	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537018028	salt bridge; other site
550537018029	non-specific DNA binding site [nucleotide binding]; other site
550537018030	sequence-specific DNA binding site [nucleotide binding]; other site
550537018031	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
550537018032	DNA-binding site [nucleotide binding]; DNA binding site
550537018033	RNA-binding motif; other site
550537018034	HMMPfam hit to PF00313, Cold-shock protein, DNA-binding, score 3.2e-44
550537018035	PS00352 'Cold-shock' DNA-binding domain signature.
550537018036	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
550537018037	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
550537018038	HMMPfam hit to PF08681, Protein of unknown function DUF1778, score 2.4e-26
550537018039	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
550537018040	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537018041	Coenzyme A binding pocket [chemical binding]; other site
550537018042	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 2.4e-11
550537018043	Integrase core domain; Region: rve; pfam00665
550537018044	Integrase core domain; Region: rve_2; pfam13333
550537018045	HMMPfam hit to PF00665, Integrase, catalytic core, score 3.2e-10
550537018047	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
550537018048	DALR anticodon binding domain; Region: DALR_1; pfam05746
550537018049	HMMPfam hit to PF05746, DALR anticodon binding, score 6.9e-05
550537018050	HMMPfam hit to PF02092, Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal, score 0
550537018051	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
550537018052	dimer interface [polypeptide binding]; other site
550537018053	motif 1; other site
550537018054	active site
550537018055	motif 2; other site
550537018056	motif 3; other site
550537018057	HMMPfam hit to PF02091, Glycyl-tRNA synthetase, class IIc, alpha subunit, score 1.8e-249
550537018058	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537018059	YsaB-like lipoprotein; Region: YsaB; pfam13983
550537018060	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018061	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
550537018062	Acyltransferase family; Region: Acyl_transf_3; pfam01757
550537018063	HMMPfam hit to PF01757, Acyltransferase 3, score 0.00017
550537018064	10 probable transmembrane helices predicted for SEN3480 by TMHMM2.0 at aa 13-30, 45-67, 79-101, 114-136, 143-160, 175-194, 201-223, 233-255, 268-288 and 303-321
550537018065	Predicted membrane protein [Function unknown]; Region: COG4682
550537018066	yiaA/B two helix domain; Region: YiaAB; cl01759
550537018067	yiaA/B two helix domain; Region: YiaAB; cl01759
550537018068	HMMPfam hit to PF05360, YiaAB two helix, score 1.7e-19
550537018069	3 probable transmembrane helices predicted for SEN3481 by TMHMM2.0 at aa 12-29, 39-54 and 71-105
550537018070	HMMPfam hit to PF05360, YiaAB two helix, score 9.3e-22
550537018071	xylulokinase; Provisional; Region: PRK15027
550537018072	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
550537018073	N- and C-terminal domain interface [polypeptide binding]; other site
550537018074	active site
550537018075	MgATP binding site [chemical binding]; other site
550537018076	catalytic site [active]
550537018077	metal binding site [ion binding]; metal-binding site
550537018078	xylulose binding site [chemical binding]; other site
550537018079	homodimer interface [polypeptide binding]; other site
550537018080	HMMPfam hit to PF02782, Carbohydrate kinase, FGGY, score 4e-107
550537018081	PS00445 FGGY family of carbohydrate kinases signature 2.
550537018082	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018083	HMMPfam hit to PF00370, Carbohydrate kinase, FGGY, score 5.2e-118
550537018084	PS00933 FGGY family of carbohydrate kinases signature 1.
550537018085	xylose isomerase; Provisional; Region: PRK05474
550537018086	xylose isomerase; Region: xylose_isom_A; TIGR02630
550537018087	HMMPfam hit to PF01261, Xylose isomerase-type TIM barrel, score 6.8e-11
550537018088	PS00172 Xylose isomerase signature 1.
550537018089	PS00173 Xylose isomerase signature 2.
550537018090	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
550537018091	putative dimerization interface [polypeptide binding]; other site
550537018092	Transcriptional regulators [Transcription]; Region: PurR; COG1609
550537018093	putative ligand binding site [chemical binding]; other site
550537018094	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537018095	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537018096	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537018097	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 9.5e-11
550537018098	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 1.8e-12
550537018099	hypothetical protein; Provisional; Region: PRK10356
550537018100	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
550537018101	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase, score 0.00044
550537018102	alpha-amylase; Reviewed; Region: malS; PRK09505
550537018103	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
550537018104	active site
550537018105	catalytic site [active]
550537018106	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 2.8e-84
550537018107	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
550537018108	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537018109	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537018110	homodimer interface [polypeptide binding]; other site
550537018111	catalytic residue [active]
550537018112	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 4.7e-10
550537018113	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
550537018114	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 8.1e-07
550537018115	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537018116	Transcriptional regulator [Transcription]; Region: IclR; COG1414
550537018117	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
550537018118	Bacterial transcriptional regulator; Region: IclR; pfam01614
550537018119	HMMPfam hit to PF01614, Transcriptional regulator IclR, C-terminal, score 2.8e-56
550537018120	HMMPfam hit to PF09339, Transcriptional regulator IclR, N-terminal, score 8.4e-30
550537018121	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
550537018122	HMMPfam hit to PF02615, Malate/L-lactate dehydrogenase, score 7.1e-198
550537018123	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
550537018124	HMMPfam hit to PF04074, Conserved hypothetical protein CHP00022, score 2.9e-77
550537018125	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
550537018126	4 probable transmembrane helices predicted for SEN3493 by TMHMM2.0 at aa 7-29, 44-66, 79-98 and 113-135
550537018127	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018128	HMMPfam hit to PF04290, Tripartite ATP-independent periplasmic transporter, DctQ component, score 9e-46
550537018129	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
550537018130	DctM-like transporters; Region: DctM; pfam06808
550537018131	11 probable transmembrane helices predicted for SEN3494 by TMHMM2.0 at aa 4-26, 47-69, 93-124, 137-159, 169-191, 212-230, 234-256, 277-299, 314-347, 354-376 and 396-418
550537018132	HMMPfam hit to PF06808, TRAP C4-dicarboxylate transport system permease DctM subunit, score 1.2e-200
550537018133	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
550537018134	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
550537018135	HMMPfam hit to PF03480, TRAP dicarboxylate transporter- DctP subunit, score 1.4e-135
550537018136	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
550537018137	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
550537018138	putative N- and C-terminal domain interface [polypeptide binding]; other site
550537018139	putative active site [active]
550537018140	MgATP binding site [chemical binding]; other site
550537018141	catalytic site [active]
550537018142	metal binding site [ion binding]; metal-binding site
550537018143	putative xylulose binding site [chemical binding]; other site
550537018144	HMMPfam hit to PF00370, Carbohydrate kinase, FGGY, score 2.8e-124
550537018145	HMMPfam hit to PF02782, Carbohydrate kinase, FGGY, score 1.6e-101
550537018146	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
550537018147	active site
550537018148	dimer interface [polypeptide binding]; other site
550537018149	magnesium binding site [ion binding]; other site
550537018150	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase, core, score 1.6e-52
550537018151	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
550537018152	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
550537018153	AP (apurinic/apyrimidinic) site pocket; other site
550537018154	DNA interaction; other site
550537018155	Metal-binding active site; metal-binding site
550537018156	HMMPfam hit to PF01261, Xylose isomerase-type TIM barrel, score 1.4e-46
550537018157	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537018158	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
550537018159	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
550537018160	intersubunit interface [polypeptide binding]; other site
550537018161	active site
550537018162	Zn2+ binding site [ion binding]; other site
550537018163	HMMPfam hit to PF00596, Class II aldolase/adducin, N-terminal, score 1e-102
550537018164	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
550537018165	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
550537018166	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537018167	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.8e-09
550537018168	PS00041 Bacterial regulatory proteins, araC family signature.
550537018169	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
550537018170	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
550537018171	HMMPfam hit to PF07944, Protein of unknown function DUF1680, score 7.8e-275
550537018172	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
550537018173	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
550537018174	NAD(P) binding site [chemical binding]; other site
550537018175	catalytic residues [active]
550537018176	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 1.7e-222
550537018177	PS00070 Aldehyde dehydrogenases cysteine active site.
550537018178	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537018179	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
550537018180	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
550537018181	nucleotide binding site [chemical binding]; other site
550537018182	HMMPfam hit to PF00480, ROK, score 1.6e-36
550537018183	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018184	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
550537018185	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
550537018186	G1 box; other site
550537018187	putative GEF interaction site [polypeptide binding]; other site
550537018188	GTP/Mg2+ binding site [chemical binding]; other site
550537018189	Switch I region; other site
550537018190	G2 box; other site
550537018191	G3 box; other site
550537018192	Switch II region; other site
550537018193	G4 box; other site
550537018194	G5 box; other site
550537018195	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
550537018196	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
550537018197	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
550537018198	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
550537018199	HMMPfam hit to PF09107, Translation elongation factor SelB, winged helix, type 3, score 1.8e-25
550537018200	HMMPfam hit to PF09106, Translation elongation factor SelB, winged helix, type 2, score 3.8e-23
550537018201	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 3.6e-11
550537018202	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 3.8e-36
550537018203	PS00301 GTP-binding elongation factors signature.
550537018204	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018205	selenocysteine synthase; Provisional; Region: PRK04311
550537018206	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
550537018207	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
550537018208	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537018209	catalytic residue [active]
550537018210	HMMPfam hit to PF03841, L-seryl-tRNA selenium transferase, score 9.6e-272
550537018211	putative glutathione S-transferase; Provisional; Region: PRK10357
550537018212	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
550537018213	putative C-terminal domain interface [polypeptide binding]; other site
550537018214	putative GSH binding site (G-site) [chemical binding]; other site
550537018215	putative dimer interface [polypeptide binding]; other site
550537018216	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
550537018217	dimer interface [polypeptide binding]; other site
550537018218	N-terminal domain interface [polypeptide binding]; other site
550537018219	putative substrate binding pocket (H-site) [chemical binding]; other site
550537018220	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 2.4e-19
550537018221	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018222	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 6.6e-06
550537018223	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
550537018224	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
550537018225	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
550537018226	active site
550537018227	P-loop; other site
550537018228	phosphorylation site [posttranslational modification]
550537018229	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537018230	active site
550537018231	phosphorylation site [posttranslational modification]
550537018232	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.7e-26
550537018233	8 probable transmembrane helices predicted for SEN3507 by TMHMM2.0 at aa 20-42, 52-74, 87-109, 129-151, 212-234, 244-263, 270-292 and 312-334
550537018234	HMMPfam hit to PF02302, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, score 1.1e-13
550537018235	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 1.1e-81
550537018236	PS00372 PTS EIIA domains phosphorylation site signature 2.
550537018237	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
550537018238	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
550537018239	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
550537018240	HMMPfam hit to PF01232, Mannitol dehydrogenase rossman, N-terminal, score 5.3e-51
550537018241	HMMPfam hit to PF08125, Mannitol dehydrogenase, C-terminal, score 3.4e-114
550537018242	PS00974 Mannitol dehydrogenases signature.
550537018243	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
550537018244	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
550537018245	HMMPfam hit to PF05068, Mannitol repressor, score 1.5e-118
550537018246	hypothetical protein; Provisional; Region: PRK11020
550537018247	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
550537018248	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018249	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
550537018250	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
550537018251	trimer interface [polypeptide binding]; other site
550537018252	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
550537018253	Haemagglutinin; Region: HIM; pfam05662
550537018254	Haemagglutinin; Region: HIM; pfam05662
550537018255	YadA-like C-terminal region; Region: YadA; pfam03895
550537018256	HMMPfam hit to PF05658, Hep/Hag, score 0.93
550537018257	HMMPfam hit to PF05658, Hep/Hag, score 0.00095
550537018258	HMMPfam hit to PF05658, Hep/Hag, score 4.9e-05
550537018259	HMMPfam hit to PF05658, Hep/Hag, score 9.7e-05
550537018260	HMMPfam hit to PF05658, Hep/Hag, score 1.3e-05
550537018261	HMMPfam hit to PF05662, Haemagluttinin motif, score 5.8e-05
550537018262	HMMPfam hit to PF05662, Haemagluttinin motif, score 7.8e-07
550537018263	HMMPfam hit to PF05662, Haemagluttinin motif, score 7.8e-07
550537018264	HMMPfam hit to PF05662, Haemagluttinin motif, score 7.8e-07
550537018265	HMMPfam hit to PF05662, Haemagluttinin motif, score 7.8e-07
550537018266	HMMPfam hit to PF05662, Haemagluttinin motif, score 1.9e-08
550537018267	HMMPfam hit to PF05662, Haemagluttinin motif, score 9.2e-08
550537018268	HMMPfam hit to PF05662, Haemagluttinin motif, score 4.5e-08
550537018269	HMMPfam hit to PF05658, Hep/Hag, score 5.1e-05
550537018270	HMMPfam hit to PF05662, Haemagluttinin motif, score 2.1e-06
550537018271	HMMPfam hit to PF05658, Hep/Hag, score 0.0002
550537018272	HMMPfam hit to PF05658, Hep/Hag, score 1.5e-05
550537018273	HMMPfam hit to PF05662, Haemagluttinin motif, score 5.5e-08
550537018274	HMMPfam hit to PF05658, Hep/Hag, score 2
550537018275	HMMPfam hit to PF05658, Hep/Hag, score 0.00012
550537018276	HMMPfam hit to PF05662, Haemagluttinin motif, score 7.5e-09
550537018277	HMMPfam hit to PF05662, Haemagluttinin motif, score 5.9e-05
550537018278	HMMPfam hit to PF03895, YadA-like, C-terminal, score 3.8e-42
550537018279	L-lactate permease; Provisional; Region: PRK10420
550537018280	glycolate transporter; Provisional; Region: PRK09695
550537018281	12 probable transmembrane helices predicted for SEN3514 by TMHMM2.0 at aa 10-32, 39-58, 68-90, 119-141, 156-178, 199-218, 244-266, 299-321, 368-387, 407-424, 434-456 and 528-550
550537018282	HMMPfam hit to PF02652, L-lactate permease, score 0
550537018283	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018284	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
550537018285	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537018286	DNA-binding site [nucleotide binding]; DNA binding site
550537018287	FCD domain; Region: FCD; pfam07729
550537018288	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 2.3e-26
550537018289	PS00043 Bacterial regulatory proteins, gntR family signature.
550537018290	HMMPfam hit to PF07729, GntR, C-terminal, score 4.7e-40
550537018291	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
550537018292	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
550537018293	active site
550537018294	substrate binding site [chemical binding]; other site
550537018295	FMN binding site [chemical binding]; other site
550537018296	putative catalytic residues [active]
550537018297	HMMPfam hit to PF01070, FMN-dependent alpha-hydroxy acid dehydrogenase, score 1.6e-226
550537018298	PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site.
550537018299	putative rRNA methylase; Provisional; Region: PRK10358
550537018300	HMMPfam hit to PF00588, tRNA/rRNA methyltransferase, SpoU, score 1.2e-43
550537018301	Transcriptional regulators [Transcription]; Region: PurR; COG1609
550537018302	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537018303	DNA binding site [nucleotide binding]
550537018304	domain linker motif; other site
550537018305	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
550537018306	putative dimerization interface [polypeptide binding]; other site
550537018307	putative ligand binding site [chemical binding]; other site
550537018308	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 5.1e-11
550537018309	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 4.3e-09
550537018310	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
550537018311	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
550537018312	active site pocket [active]
550537018313	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 1.3e-08
550537018314	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 3e-39
550537018315	PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2.
550537018316	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537018317	D-galactonate transporter; Region: 2A0114; TIGR00893
550537018318	putative substrate translocation pore; other site
550537018319	12 probable transmembrane helices predicted for SEN3520 by TMHMM2.0 at aa 13-35, 50-72, 79-101, 105-127, 140-162, 172-189, 240-262, 277-299, 311-333, 338-360, 372-394 and 404-426
550537018320	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5e-57
550537018321	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018322	serine acetyltransferase; Provisional; Region: cysE; PRK11132
550537018323	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
550537018324	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
550537018325	trimer interface [polypeptide binding]; other site
550537018326	active site
550537018327	substrate binding site [chemical binding]; other site
550537018328	CoA binding site [chemical binding]; other site
550537018329	PS00101 Hexapeptide-repeat containing-transferases signature.
550537018330	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 2.2
550537018331	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 9.9
550537018332	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.93
550537018333	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 1.2e+02
550537018334	HMMPfam hit to PF06426, Serine acetyltransferase, N-terminal, score 8.8e-66
550537018335	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
550537018336	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
550537018337	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
550537018338	HMMPfam hit to PF07479, NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal, score 2e-80
550537018339	PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature.
550537018340	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal, score 1.2e-81
550537018341	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
550537018342	SecA binding site; other site
550537018343	Preprotein binding site; other site
550537018344	HMMPfam hit to PF02556, Bacterial protein export chaperone SecB, score 1.2e-101
550537018345	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
550537018346	GSH binding site [chemical binding]; other site
550537018347	catalytic residues [active]
550537018348	HMMPfam hit to PF00462, Glutaredoxin, score 6.3e-29
550537018349	PS00195 Glutaredoxin active site.
550537018350	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
550537018351	active site residue [active]
550537018352	HMMPfam hit to PF00581, Rhodanese-like, score 2e-22
550537018353	1 probable transmembrane helix predicted for SEN3525 by TMHMM2.0 at aa 7-29
550537018354	phosphoglyceromutase; Provisional; Region: PRK05434
550537018355	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
550537018356	HMMPfam hit to PF06415, BPG-independent PGAM, N-terminal, score 3.1e-255
550537018357	HMMPfam hit to PF01676, Metalloenzyme, score 5.7e-58
550537018358	AmiB activator; Provisional; Region: PRK11637
550537018359	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
550537018360	Peptidase family M23; Region: Peptidase_M23; pfam01551
550537018361	1 probable transmembrane helix predicted for SEN3527 by TMHMM2.0 at aa 20-42
550537018362	HMMPfam hit to PF01551, Peptidase M23B, score 6.1e-48
550537018363	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
550537018364	NodB motif; other site
550537018365	putative active site [active]
550537018366	putative catalytic site [active]
550537018367	Zn binding site [ion binding]; other site
550537018368	1 probable transmembrane helix predicted for SEN3528 by TMHMM2.0 at aa 7-29
550537018369	HMMPfam hit to PF04748, Protein of unknown function DUF610, YibQ, score 8e-119
550537018370	putative glycosyl transferase; Provisional; Region: PRK10073
550537018371	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
550537018372	active site
550537018373	HMMPfam hit to PF00535, Glycosyl transferase, family 2, score 5.8e-41
550537018374	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
550537018375	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
550537018376	NAD(P) binding site [chemical binding]; other site
550537018377	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 1.2e-39
550537018378	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 6e-47
550537018379	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537018380	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
550537018381	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
550537018382	substrate-cofactor binding pocket; other site
550537018383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537018384	catalytic residue [active]
550537018385	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 2.9e-113
550537018386	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
550537018387	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
550537018388	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
550537018389	NADP binding site [chemical binding]; other site
550537018390	homopentamer interface [polypeptide binding]; other site
550537018391	substrate binding site [chemical binding]; other site
550537018392	active site
550537018393	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 2.2e-51
550537018394	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
550537018395	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
550537018396	putative active site [active]
550537018397	HMMPfam hit to PF01075, Glycosyl transferase, family 9, score 1.1e-117
550537018398	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
550537018399	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
550537018400	putative active site [active]
550537018401	PS00974 Mannitol dehydrogenases signature.
550537018402	HMMPfam hit to PF01075, Glycosyl transferase, family 9, score 9.9e-120
550537018403	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
550537018404	O-antigen ligase RfaL; Provisional; Region: PRK15487
550537018405	10 probable transmembrane helices predicted for SEN3535 by TMHMM2.0 at aa 21-53, 68-85, 126-145, 160-182, 189-206, 210-225, 230-247, 325-347, 360-379 and 383-401
550537018406	HMMPfam hit to PF04932, O-antigen polymerase, score 3e-19
550537018407	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
550537018408	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
550537018409	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 3.7e-54
550537018410	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
550537018411	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
550537018412	HMMPfam hit to PF06176, Lipopolysaccharide core biosynthesis, score 7e-189
550537018413	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
550537018414	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
550537018415	Ligand binding site; other site
550537018416	metal-binding site
550537018417	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
550537018418	HMMPfam hit to PF08437, Glycosyl transferase, family 8, C-terminal, score 3.6e-32
550537018419	HMMPfam hit to PF01501, Glycosyl transferase, family 8, score 1e-86
550537018420	PS00430 TonB-dependent receptor proteins signature 1.
550537018421	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
550537018422	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
550537018423	Ligand binding site; other site
550537018424	metal-binding site
550537018425	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
550537018426	HMMPfam hit to PF08437, Glycosyl transferase, family 8, C-terminal, score 7e-34
550537018427	HMMPfam hit to PF01501, Glycosyl transferase, family 8, score 1e-87
550537018428	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
550537018429	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
550537018430	putative ADP-binding pocket [chemical binding]; other site
550537018431	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 7.1e-37
550537018432	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
550537018433	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
550537018434	HMMPfam hit to PF01501, Glycosyl transferase, family 8, score 6.8e-06
550537018435	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
550537018436	HMMPfam hit to PF06293, Lipopolysaccharide kinase, score 6.3e-88
550537018437	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
550537018438	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
550537018439	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 2.5e-37
550537018440	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537018441	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
550537018442	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
550537018443	putative active site [active]
550537018444	HMMPfam hit to PF01075, Glycosyl transferase, family 9, score 1.4e-84
550537018445	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
550537018446	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
550537018447	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
550537018448	HMMPfam hit to PF04413, Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal, score 1.8e-115
550537018449	HMMPfam hit to PF00534, Glycosyl transferase, group 1, score 9e-08
550537018450	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
550537018451	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
550537018452	active site
550537018453	(T/H)XGH motif; other site
550537018454	HMMPfam hit to PF01467, Cytidylyltransferase, score 2.1e-39
550537018455	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
550537018456	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
550537018457	DNA binding site [nucleotide binding]
550537018458	catalytic residue [active]
550537018459	H2TH interface [polypeptide binding]; other site
550537018460	putative catalytic residues [active]
550537018461	turnover-facilitating residue; other site
550537018462	intercalation triad [nucleotide binding]; other site
550537018463	8OG recognition residue [nucleotide binding]; other site
550537018464	putative reading head residues; other site
550537018465	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
550537018466	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
550537018467	HMMPfam hit to PF06827, Formamidopyrimidine-DNA glycolase, C-terminal, score 0.00056
550537018468	PS01242 Formamidopyrimidine-DNA glycosylase signature.
550537018469	HMMPfam hit to PF06831, Formamidopyrimidine-DNA glycolase, H2TH DNA binding, score 1.3e-51
550537018470	HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase, catalytic, score 3.2e-47
550537018471	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
550537018472	HMMPfam hit to PF00471, Ribosomal protein L33, score 1.5e-24
550537018473	PS00582 Ribosomal protein L33 signature.
550537018474	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
550537018475	HMMPfam hit to PF00830, Ribosomal protein L28, score 8.1e-35
550537018476	hypothetical protein; Reviewed; Region: PRK00024
550537018477	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
550537018478	MPN+ (JAMM) motif; other site
550537018479	Zinc-binding site [ion binding]; other site
550537018480	HMMPfam hit to PF04002, DNA repair protein RadC, score 6.4e-82
550537018481	PS01302 DNA repair protein radC family signature.
550537018482	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
550537018483	Flavoprotein; Region: Flavoprotein; pfam02441
550537018484	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
550537018485	HMMPfam hit to PF02441, Flavoprotein, score 1.3e-47
550537018486	HMMPfam hit to PF04127, DNA/pantothenate metabolism flavoprotein, C-terminal, score 3.8e-35
550537018487	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018488	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
550537018489	trimer interface [polypeptide binding]; other site
550537018490	active site
550537018491	HMMPfam hit to PF00692, DeoxyUTP pyrophosphatase, score 1.4e-55
550537018492	division inhibitor protein; Provisional; Region: slmA; PRK09480
550537018493	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537018494	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 2e-11
550537018495	PS01081 Bacterial regulatory proteins, tetR family signature.
550537018496	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
550537018497	active site
550537018498	HMMPfam hit to PF00156, Phosphoribosyltransferase, score 6.7e-33
550537018499	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
550537018500	ribonuclease PH; Reviewed; Region: rph; PRK00173
550537018501	Ribonuclease PH; Region: RNase_PH_bact; cd11362
550537018502	hexamer interface [polypeptide binding]; other site
550537018503	active site
550537018504	HMMPfam hit to PF03725, Exoribonuclease, phosphorolytic domain 2, score 1.2e-23
550537018505	HMMPfam hit to PF01138, Exoribonuclease, phosphorolytic domain 1, score 1.7e-56
550537018506	PS01277 Ribonuclease PH signature.
550537018507	hypothetical protein; Provisional; Region: PRK11820
550537018508	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
550537018509	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
550537018510	HMMPfam hit to PF03755, YicC-like, N-terminal, score 1.9e-86
550537018511	HMMPfam hit to PF08340, Region of unknown function DUF1732, score 7.5e-57
550537018512	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537018513	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537018514	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
550537018515	dimerization interface [polypeptide binding]; other site
550537018516	HMMPfam hit to PF03466, LysR, substrate-binding, score 5.1e-07
550537018517	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.9e-10
550537018518	PS00044 Bacterial regulatory proteins, lysR family signature.
550537018519	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
550537018520	HMMPfam hit to PF00753, Beta-lactamase-like, score 6.6e-15
550537018521	Predicted membrane protein [Function unknown]; Region: COG2860
550537018522	UPF0126 domain; Region: UPF0126; pfam03458
550537018523	UPF0126 domain; Region: UPF0126; pfam03458
550537018524	HMMPfam hit to PF03458, Protein of unknown function UPF0126, score 8.8e-37
550537018525	7 probable transmembrane helices predicted for SEN3560 by TMHMM2.0 at aa 5-22, 29-51, 64-81, 88-109, 114-136, 148-167 and 172-189
550537018526	HMMPfam hit to PF03458, Protein of unknown function UPF0126, score 4.3e-34
550537018527	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
550537018528	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
550537018529	nucleotide binding pocket [chemical binding]; other site
550537018530	K-X-D-G motif; other site
550537018531	catalytic site [active]
550537018532	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
550537018533	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537018534	HMMPfam hit to PF03120, NAD-dependent DNA ligase, OB-fold, score 2.9e-24
550537018535	PS01056 NAD-dependent DNA ligase signature 2.
550537018536	HMMPfam hit to PF01653, NAD-dependent DNA ligase, adenylation, score 2.5e-80
550537018537	PS01055 NAD-dependent DNA ligase signature 1.
550537018538	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
550537018539	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
550537018540	catalytic site [active]
550537018541	G-X2-G-X-G-K; other site
550537018542	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018543	PS00856 Guanylate kinase signature.
550537018544	HMMPfam hit to PF00625, Guanylate kinase, score 4.4e-63
550537018545	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
550537018546	HMMPfam hit to PF01192, RNA polymerase Rpb6, score 3.8e-23
550537018547	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
550537018548	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
550537018549	Zn2+ binding site [ion binding]; other site
550537018550	Mg2+ binding site [ion binding]; other site
550537018551	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
550537018552	synthetase active site [active]
550537018553	NTP binding site [chemical binding]; other site
550537018554	metal binding site [ion binding]; metal-binding site
550537018555	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
550537018556	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
550537018557	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018558	HMMPfam hit to PF01966, Metal-dependent phosphohydrolase, HD region, subdomain, score 6.5e-20
550537018559	HMMPfam hit to PF04607, RelA/SpoT, score 1.5e-45
550537018560	HMMPfam hit to PF02824, TGS, score 2.1e-28
550537018561	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
550537018562	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
550537018563	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
550537018564	HMMPfam hit to PF00588, tRNA/rRNA methyltransferase, SpoU, score 1e-53
550537018565	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
550537018566	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
550537018567	generic binding surface II; other site
550537018568	ssDNA binding site; other site
550537018569	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537018570	ATP binding site [chemical binding]; other site
550537018571	putative Mg++ binding site [ion binding]; other site
550537018572	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537018573	nucleotide binding region [chemical binding]; other site
550537018574	ATP-binding site [chemical binding]; other site
550537018575	HMMPfam hit to PF01336, Nucleic acid binding, OB-fold, tRNA/helicase-type, score 2.2e-11
550537018576	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 1.1e-34
550537018577	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018578	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 8.4e-25
550537018579	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
550537018580	9 probable transmembrane helices predicted for SEN3567 by TMHMM2.0 at aa 70-87, 94-116, 157-179, 213-235, 245-267, 274-292, 302-324, 336-358 and 368-390
550537018581	HMMPfam hit to PF03616, Sodium/glutamate symporter, score 3.2e-246
550537018582	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
550537018583	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018584	HMMPfam hit to PF00860, Xanthine/uracil/vitamin C permease, score 2.1e-158
550537018585	11 probable transmembrane helices predicted for SEN3568 by TMHMM2.0 at aa 43-65, 90-112, 127-149, 156-178, 193-212, 219-241, 261-283, 346-368, 378-400, 407-429 and 439-458
550537018586	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018587	PS01116 Xanthine/uracil permeases family signature.
550537018588	AsmA family; Region: AsmA; pfam05170
550537018589	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
550537018590	HMMPfam hit to PF05170, AsmA, score 2e-243
550537018591	1 probable transmembrane helix predicted for SEN3569 by TMHMM2.0 at aa 7-26
550537018592	putative alpha-glucosidase; Provisional; Region: PRK10658
550537018593	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
550537018594	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
550537018595	active site
550537018596	homotrimer interface [polypeptide binding]; other site
550537018597	catalytic site [active]
550537018598	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
550537018599	HMMPfam hit to PF01055, Glycoside hydrolase, family 31, score 3.5e-182
550537018600	putative transporter; Provisional; Region: PRK11462
550537018601	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
550537018602	11 probable transmembrane helices predicted for SEN3571 by TMHMM2.0 at aa 32-54, 81-100, 115-137, 150-170, 180-202, 232-254, 264-286, 293-315, 319-341, 362-384 and 399-421
550537018603	PS00872 Sodium:galactoside symporter family signature.
550537018604	Salmonella pathogenicity Island 3: SPI-3
550537018605	The CDS contains multiple frameshift-mutations
550537018606	HMMPfam hit to PF02463, SMC protein, N-terminal, score 7.3e-06
550537018607	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018608	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
550537018609	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018610	Virulence protein [General function prediction only]; Region: COG3943
550537018611	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
550537018613	HMMPfam hit to PF01527, Transposase IS3/IS911, score 1.4e-08
550537018615	autotransport protein MisL; Provisional; Region: PRK15313
550537018616	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
550537018617	Autotransporter beta-domain; Region: Autotransporter; pfam03797
550537018618	1 probable transmembrane helix predicted for SEN3580 by TMHMM2.0 at aa 7-29
550537018619	HMMPfam hit to PF03212, Pertactin, score 0.00014
550537018620	HMMPfam hit to PF03797, Autotransporter beta-domain, score 7.4e-37
550537018621	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
550537018622	DNA binding site [nucleotide binding]
550537018623	1 probable transmembrane helix predicted for SEN3582 by TMHMM2.0 at aa 147-169
550537018624	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 3.4e-18
550537018625	Isochorismatase family; Region: Isochorismatase; pfam00857
550537018626	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
550537018627	catalytic triad [active]
550537018628	dimer interface [polypeptide binding]; other site
550537018629	conserved cis-peptide bond; other site
550537018630	HMMPfam hit to PF00857, Isochorismatase hydrolase, score 2.8e-20
550537018631	2 probable transmembrane helices predicted for SEN3584 by TMHMM2.0 at aa 7-26 and 135-157
550537018632	magnesium-transporting ATPase; Provisional; Region: PRK15122
550537018633	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
550537018634	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
550537018635	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
550537018636	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537018637	motif II; other site
550537018638	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
550537018639	8 probable transmembrane helices predicted for SEN3585 by TMHMM2.0 at aa 87-105, 115-134, 293-315, 325-347, 719-741, 779-801, 844-866 and 876-893
550537018640	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.9e-19
550537018641	PS00154 E1-E2 ATPases phosphorylation site.
550537018642	HMMPfam hit to PF00122, E1-E2 ATPase-associated region, score 1.6e-86
550537018643	HMMPfam hit to PF00690, ATPase, P-type cation-transporter, N-terminal, score 1.1e-22
550537018644	magnesium transport protein MgtC; Provisional; Region: PRK15385
550537018645	MgtC family; Region: MgtC; pfam02308
550537018646	HMMPfam hit to PF02308, MgtC/SapB transporter, score 1.6e-76
550537018647	4 probable transmembrane helices predicted for SEN3586 by TMHMM2.0 at aa 5-27, 34-56, 66-83 and 90-112
550537018648	EamA-like transporter family; Region: EamA; pfam00892
550537018649	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
550537018650	EamA-like transporter family; Region: EamA; pfam00892
550537018651	10 probable transmembrane helices predicted for SEN3587 by TMHMM2.0 at aa 7-29, 39-59, 72-94, 98-120, 127-144, 154-176, 183-205, 215-237, 250-272 and 276-293
550537018652	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 1.5e-16
550537018653	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2.6e-24
550537018654	hypothetical protein; Provisional; Region: PRK09956
550537018655	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
550537018656	HMMPfam hit to PF04754, Transposase (), YhgA-like, score 1.2e-205
550537018657	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
550537018658	HMMPfam hit to PF07071, Protein of unknown function DUF1341, score 1.3e-165
550537018659	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
550537018660	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
550537018661	HMMPfam hit to PF03841, L-seryl-tRNA selenium transferase, score 1.3e-09
550537018662	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537018663	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
550537018664	HMMPfam hit to PF03613, Phosphotransferase system, mannose/fructose/sorbose family IID component, score 1e-84
550537018665	5 probable transmembrane helices predicted for SEN3591 by TMHMM2.0 at aa 128-147, 151-173, 197-216, 236-258 and 265-284
550537018666	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
550537018667	HMMPfam hit to PF03609, Phosphotransferase system, sorbose-specific IIC subunit, score 5.9e-40
550537018668	5 probable transmembrane helices predicted for SEN3592 by TMHMM2.0 at aa 21-43, 93-110, 141-163, 183-203 and 210-232
550537018669	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
550537018670	active site
550537018671	phosphorylation site [posttranslational modification]
550537018672	HMMPfam hit to PF03830, Phosphotransferase system, sorbose subfamily IIB component, score 1e-30
550537018673	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
550537018674	active pocket/dimerization site; other site
550537018675	active site
550537018676	phosphorylation site [posttranslational modification]
550537018677	HMMPfam hit to PF03610, Phosphotransferase system, fructose subfamily IIA component, score 2.6e-14
550537018678	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
550537018679	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537018680	Walker A motif; other site
550537018681	ATP binding site [chemical binding]; other site
550537018682	Walker B motif; other site
550537018683	arginine finger; other site
550537018684	Transcriptional antiterminator [Transcription]; Region: COG3933
550537018685	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
550537018686	active site
550537018687	active pocket/dimerization site; other site
550537018688	phosphorylation site [posttranslational modification]
550537018689	PRD domain; Region: PRD; pfam00874
550537018690	HMMPfam hit to PF00874, PRD, score 5.6e-16
550537018691	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 7.3e-62
550537018692	PS00690 DEAH-box subfamily ATP-dependent helicases signature.
550537018693	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018694	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
550537018695	beta-galactosidase; Region: BGL; TIGR03356
550537018696	HMMPfam hit to PF00232, Glycoside hydrolase, family 1, score 2.7e-134
550537018697	PS00572 Glycosyl hydrolases family 1 active site.
550537018698	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
550537018699	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537018700	putative substrate translocation pore; other site
550537018701	12 probable transmembrane helices predicted for SEN3598 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 110-132, 145-167, 177-196, 217-239, 254-276, 283-302, 307-329, 341-363 and 367-389
550537018702	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018703	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4.4e-40
550537018704	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018705	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
550537018706	HMMPfam hit to PF06296, Protein of unknown function DUF1044, score 3.5e-77
550537018707	Predicted transcriptional regulator [Transcription]; Region: COG2944
550537018708	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537018709	non-specific DNA binding site [nucleotide binding]; other site
550537018710	salt bridge; other site
550537018711	sequence-specific DNA binding site [nucleotide binding]; other site
550537018712	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 7.1e-08
550537018713	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
550537018714	HMMPfam hit to PF06711, Protein of unknown function DUF1198, score 6.1e-131
550537018715	1 probable transmembrane helix predicted for SEN3601 by TMHMM2.0 at aa 4-21
550537018716	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
550537018717	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537018718	putative substrate translocation pore; other site
550537018719	12 probable transmembrane helices predicted for SEN3602 by TMHMM2.0 at aa 28-45, 67-89, 96-118, 123-145, 158-180, 190-212, 254-276, 296-318, 325-347, 357-379, 392-411 and 426-445
550537018720	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.4e-32
550537018721	PS00942 glpT family of transporters signature.
550537018722	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018723	regulatory protein UhpC; Provisional; Region: PRK11663
550537018724	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537018725	putative substrate translocation pore; other site
550537018726	12 probable transmembrane helices predicted for SEN3603 by TMHMM2.0 at aa 26-45, 67-89, 96-118, 122-144, 156-178, 183-205, 245-267, 287-309, 322-344, 348-370, 377-399 and 409-431
550537018727	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4.4e-59
550537018728	PS00942 glpT family of transporters signature.
550537018729	sensory histidine kinase UhpB; Provisional; Region: PRK11644
550537018730	MASE1; Region: MASE1; pfam05231
550537018731	Histidine kinase; Region: HisKA_3; pfam07730
550537018732	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537018733	ATP binding site [chemical binding]; other site
550537018734	Mg2+ binding site [ion binding]; other site
550537018735	G-X-G motif; other site
550537018736	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 6.9e-21
550537018737	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018738	HMMPfam hit to PF07730, Histidine kinase, dimerisation and phosphoacceptor region, score 5.5e-17
550537018739	HMMPfam hit to PF05231, MASE1, score 2.4e-67
550537018740	7 probable transmembrane helices predicted for SEN3604 by TMHMM2.0 at aa 7-29, 78-100, 112-130, 140-162, 186-205, 220-242 and 255-274
550537018741	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
550537018742	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537018743	active site
550537018744	phosphorylation site [posttranslational modification]
550537018745	intermolecular recognition site; other site
550537018746	dimerization interface [polypeptide binding]; other site
550537018747	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537018748	DNA binding residues [nucleotide binding]
550537018749	dimerization interface [polypeptide binding]; other site
550537018750	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 5.6e-29
550537018751	PS00622 Bacterial regulatory proteins, luxR family signature.
550537018752	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018753	HMMPfam hit to PF00072, Response regulator receiver, score 1.2e-39
550537018754	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
550537018755	active site
550537018756	catalytic residues [active]
550537018757	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
550537018758	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
550537018759	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537018760	putative substrate translocation pore; other site
550537018761	12 probable transmembrane helices predicted for SEN3608 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 109-128, 149-171, 205-227, 256-275, 290-312, 319-336, 340-362, 375-397 and 401-423
550537018762	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 3.8e-25
550537018763	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018764	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537018765	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
550537018766	substrate binding site [chemical binding]; other site
550537018767	dimer interface [polypeptide binding]; other site
550537018768	ATP binding site [chemical binding]; other site
550537018769	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 3.5e-64
550537018770	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
550537018771	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
550537018772	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537018773	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 2.4e-07
550537018774	PS00894 Bacterial regulatory proteins, deoR family signature.
550537018775	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 1.8e-30
550537018776	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
550537018777	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
550537018778	putative valine binding site [chemical binding]; other site
550537018779	dimer interface [polypeptide binding]; other site
550537018780	HMMPfam hit to PF01842, Amino acid-binding ACT, score 1.3e-09
550537018781	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
550537018782	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
550537018783	PYR/PP interface [polypeptide binding]; other site
550537018784	dimer interface [polypeptide binding]; other site
550537018785	TPP binding site [chemical binding]; other site
550537018786	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
550537018787	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
550537018788	TPP-binding site [chemical binding]; other site
550537018789	dimer interface [polypeptide binding]; other site
550537018790	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding, score 9.2e-68
550537018791	PS00187 Thiamine pyrophosphate enzymes signature.
550537018792	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018793	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central region, score 6e-66
550537018794	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding region, score 2e-107
550537018795	HMMPfam hit to PF08049, IlvB leader peptide, score 7.7e-13
550537018796	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
550537018797	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
550537018798	10 probable transmembrane helices predicted for SEN3614 by TMHMM2.0 at aa 4-23, 30-52, 57-76, 89-108, 112-134, 141-158, 168-190, 207-226, 230-252 and 257-276
550537018799	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 6.9e-05
550537018800	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018801	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 7.5e-07
550537018802	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
550537018803	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537018804	putative substrate translocation pore; other site
550537018805	12 probable transmembrane helices predicted for SEN3615 by TMHMM2.0 at aa 7-29, 44-66, 75-94, 98-120, 133-155, 165-182, 203-225, 240-262, 275-297, 301-323, 330-352 and 362-384
550537018806	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4e-46
550537018807	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018808	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
550537018809	1 probable transmembrane helix predicted for SEN3616 by TMHMM2.0 at aa 7-26
550537018810	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
550537018811	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537018812	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
550537018813	dimerization interface [polypeptide binding]; other site
550537018814	substrate binding pocket [chemical binding]; other site
550537018815	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.4e-26
550537018816	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2e-20
550537018817	PS00044 Bacterial regulatory proteins, lysR family signature.
550537018818	permease DsdX; Provisional; Region: PRK09921
550537018819	gluconate transporter; Region: gntP; TIGR00791
550537018820	12 probable transmembrane helices predicted for SEN3618 by TMHMM2.0 at aa 4-23, 30-49, 54-76, 104-126, 146-168, 175-197, 226-248, 261-283, 303-322, 343-365, 385-407 and 420-442
550537018821	HMMPfam hit to PF02447, Gluconate transporter, score 5.3e-245
550537018822	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018823	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
550537018824	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
550537018825	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
550537018826	catalytic residue [active]
550537018827	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 9.6e-54
550537018828	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
550537018829	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018830	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
550537018831	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
550537018832	Domain of unknown function (DUF202); Region: DUF202; pfam02656
550537018833	3 probable transmembrane helices predicted for SEN3621 by TMHMM2.0 at aa 21-43, 48-70 and 91-113
550537018834	Predicted membrane protein [Function unknown]; Region: COG2149
550537018835	HMMPfam hit to PF02656, Protein of unknown function DUF202, score 1.3e-67
550537018836	3 probable transmembrane helices predicted for SEN3622 by TMHMM2.0 at aa 21-40, 50-72 and 92-114
550537018837	putative transporter; Validated; Region: PRK03818
550537018838	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
550537018839	TrkA-C domain; Region: TrkA_C; pfam02080
550537018840	TrkA-C domain; Region: TrkA_C; pfam02080
550537018841	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
550537018842	11 probable transmembrane helices predicted for SEN3623 by TMHMM2.0 at aa 4-21, 28-46, 61-83, 95-117, 160-182, 374-396, 400-419, 431-448, 463-485, 492-514 and 529-551
550537018843	HMMPfam hit to PF06826, YidE/YbjL duplication, score 7e-66
550537018844	HMMPfam hit to PF02080, TrkA-C, score 1.6e-12
550537018845	HMMPfam hit to PF02080, TrkA-C, score 5.3e-10
550537018846	HMMPfam hit to PF06826, YidE/YbjL duplication, score 1.8e-61
550537018847	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
550537018848	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
550537018849	putative dimer interface [polypeptide binding]; other site
550537018850	HMMPfam hit to PF00011, Heat shock protein Hsp20, score 2.2e-26
550537018851	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
550537018852	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
550537018853	putative dimer interface [polypeptide binding]; other site
550537018854	HMMPfam hit to PF00011, Heat shock protein Hsp20, score 7.9e-32
550537018855	hypothetical protein; Provisional; Region: PRK11616
550537018856	HMMPfam hit to PF07119, Protein of unknown function DUF1375, score 4.1e-40
550537018857	1 probable transmembrane helix predicted for SEN3626 by TMHMM2.0 at aa 7-29
550537018858	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018859	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
550537018860	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018861	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
550537018862	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
550537018863	2 probable transmembrane helices predicted for SEN3628 by TMHMM2.0 at aa 103-125 and 150-172
550537018864	HMMPfam hit to PF03918, Cytochrome C biogenesis protein, score 2.2e-71
550537018865	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
550537018866	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
550537018867	catalytic residues [active]
550537018868	central insert; other site
550537018869	HMMPfam hit to PF08534, Redoxin, score 2.5e-27
550537018870	PS00194 Thioredoxin family active site.
550537018871	1 probable transmembrane helix predicted for SEN3629 by TMHMM2.0 at aa 5-24
550537018872	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
550537018873	15 probable transmembrane helices predicted for SEN3630 by TMHMM2.0 at aa 5-27, 40-62, 95-114, 121-143, 176-198, 211-233, 248-265, 277-299, 314-332, 353-375, 390-412, 425-444, 449-468, 481-503 and 610-629
550537018874	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018875	HMMPfam hit to PF01578, Cytochrome c assembly protein, score 1.3e-82
550537018876	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
550537018877	HMMPfam hit to PF03100, CcmE/CycJ protein, score 1.2e-90
550537018878	1 probable transmembrane helix predicted for SEN3631 by TMHMM2.0 at aa 7-29
550537018879	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
550537018880	HMMPfam hit to PF04995, Heme exporter protein D (CcmD), score 2.7e-16
550537018881	1 probable transmembrane helix predicted for SEN3632 by TMHMM2.0 at aa 15-37
550537018882	heme exporter protein CcmC; Region: ccmC; TIGR01191
550537018883	6 probable transmembrane helices predicted for SEN3633 by TMHMM2.0 at aa 21-43, 63-85, 92-114, 129-148, 155-177 and 204-226
550537018884	HMMPfam hit to PF01578, Cytochrome c assembly protein, score 5e-57
550537018885	ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CcmB; COG2386
550537018886	HMMPfam hit to PF03379, Cytochrome c-type biogenesis protein CcmB, score 6.4e-113
550537018887	6 probable transmembrane helices predicted for SEN3634 by TMHMM2.0 at aa 20-39, 43-65, 96-118, 128-150, 157-179 and 194-216
550537018888	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
550537018889	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537018890	Walker A/P-loop; other site
550537018891	ATP binding site [chemical binding]; other site
550537018892	Q-loop/lid; other site
550537018893	ABC transporter signature motif; other site
550537018894	Walker B; other site
550537018895	D-loop; other site
550537018896	H-loop/switch region; other site
550537018897	HMMPfam hit to PF00005, ABC transporter related, score 1.4e-48
550537018898	PS00211 ABC transporters family signature.
550537018899	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018900	Haem-binding domain; Region: Haem_bd; pfam14376
550537018901	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
550537018902	PS00190 Cytochrome c family heme-binding site signature.
550537018903	HMMPfam hit to PF03150, Di-haem cytochrome c peroxidase, score 1.1e-109
550537018904	PS00190 Cytochrome c family heme-binding site signature.
550537018905	PS00190 Cytochrome c family heme-binding site signature.
550537018906	1 probable transmembrane helix predicted for SEN3636 by TMHMM2.0 at aa 7-29
550537018907	chaperone protein TorD; Validated; Region: torD; PRK04976
550537018908	HMMPfam hit to PF06192, Cytoplasmic chaperone TorD, score 1.5e-50
550537018909	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
550537018910	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
550537018911	molybdopterin cofactor binding site [chemical binding]; other site
550537018912	substrate binding site [chemical binding]; other site
550537018913	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
550537018914	molybdopterin cofactor binding site; other site
550537018915	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 3.2e-32
550537018916	PS00932 Prokaryotic molybdopterin oxidoreductases signature 3.
550537018917	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 3.3e-183
550537018918	PS00490 Prokaryotic molybdopterin oxidoreductases signature 2.
550537018919	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
550537018920	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
550537018921	PS00190 Cytochrome c family heme-binding site signature.
550537018922	HMMPfam hit to PF03264, NapC/NirT cytochrome c, N-terminal, score 6.1e-122
550537018923	PS00190 Cytochrome c family heme-binding site signature.
550537018924	PS00190 Cytochrome c family heme-binding site signature.
550537018925	PS00190 Cytochrome c family heme-binding site signature.
550537018926	1 probable transmembrane helix predicted for SEN3639 by TMHMM2.0 at aa 12-34
550537018927	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
550537018928	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537018929	active site
550537018930	phosphorylation site [posttranslational modification]
550537018931	intermolecular recognition site; other site
550537018932	dimerization interface [polypeptide binding]; other site
550537018933	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537018934	DNA binding site [nucleotide binding]
550537018935	HMMPfam hit to PF00072, Response regulator receiver, score 4.5e-40
550537018936	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 4.1e-15
550537018937	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
550537018938	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
550537018939	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 7.4e-98
550537018940	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
550537018941	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537018942	dimer interface [polypeptide binding]; other site
550537018943	phosphorylation site [posttranslational modification]
550537018944	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537018945	ATP binding site [chemical binding]; other site
550537018946	Mg2+ binding site [ion binding]; other site
550537018947	G-X-G motif; other site
550537018948	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537018949	active site
550537018950	phosphorylation site [posttranslational modification]
550537018951	intermolecular recognition site; other site
550537018952	dimerization interface [polypeptide binding]; other site
550537018953	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
550537018954	putative binding surface; other site
550537018955	active site
550537018956	2 probable transmembrane helices predicted for SEN3642 by TMHMM2.0 at aa 10-32 and 332-354
550537018957	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1.2e-09
550537018958	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 3.2e-19
550537018959	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 6.4e-40
550537018960	HMMPfam hit to PF00072, Response regulator receiver, score 5.7e-18
550537018961	PS00017 ATP/GTP-binding site motif A (P-loop).
550537018962	HMMPfam hit to PF01627, Hpt, score 4e-13
550537018963	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537018964	D-galactonate transporter; Region: 2A0114; TIGR00893
550537018965	putative substrate translocation pore; other site
550537018966	12 probable transmembrane helices predicted for SEN3643 by TMHMM2.0 at aa 31-53, 68-90, 97-117, 122-144, 156-178, 182-203, 257-278, 293-315, 322-344, 354-376, 389-411 and 416-438
550537018967	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 7.8e-68
550537018968	galactonate dehydratase; Provisional; Region: PRK14017
550537018969	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
550537018970	putative active site pocket [active]
550537018971	putative metal binding site [ion binding]; other site
550537018972	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537018973	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 4.3e-24
550537018974	PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2.
550537018975	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 4.4e-56
550537018976	PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1.
550537018977	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
550537018978	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
550537018979	active site
550537018980	intersubunit interface [polypeptide binding]; other site
550537018981	catalytic residue [active]
550537018982	HMMPfam hit to PF01081, KDPG and KHG aldolase, score 1.6e-11
550537018983	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
550537018984	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
550537018985	HMMPfam hit to PF05035, 2-keto-3-deoxy-galactonokinase, score 1.5e-181
550537018986	Transcriptional regulators [Transcription]; Region: FadR; COG2186
550537018987	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537018988	DNA-binding site [nucleotide binding]; DNA binding site
550537018989	FCD domain; Region: FCD; pfam07729
550537018990	HMMPfam hit to PF07729, GntR, C-terminal, score 3.2e-35
550537018991	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 8.2e-16
550537018992	PS00043 Bacterial regulatory proteins, gntR family signature.
550537018993	sugar phosphate phosphatase; Provisional; Region: PRK10513
550537018994	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537018995	active site
550537018996	motif I; other site
550537018997	motif II; other site
550537018998	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537018999	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 4.1e-94
550537019000	PS01229 Hypothetical cof family signature 2.
550537019001	PS01228 Hypothetical cof family signature 1.
550537019002	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537019003	D-galactonate transporter; Region: 2A0114; TIGR00893
550537019004	putative substrate translocation pore; other site
550537019005	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537019006	12 probable transmembrane helices predicted for SEN3649 by TMHMM2.0 at aa 13-35, 55-77, 89-111, 115-132, 145-167, 172-194, 239-261, 276-298, 305-324, 334-353, 366-388 and 393-415
550537019007	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4.2e-58
550537019008	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
550537019009	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
550537019010	active site pocket [active]
550537019011	HMMPfam hit to PF02746, Mandelate racemase/muconate lactonizing enzyme, N-terminal, score 1.5e-24
550537019012	HMMPfam hit to PF01188, Mandelate racemase/muconate lactonizing enzyme, C-terminal, score 1.8e-15
550537019013	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537019014	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537019015	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
550537019016	putative dimerization interface [polypeptide binding]; other site
550537019017	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 3.3e-18
550537019018	PS00044 Bacterial regulatory proteins, lysR family signature.
550537019019	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.6e-24
550537019020	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
550537019021	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537019022	Mg2+ binding site [ion binding]; other site
550537019023	G-X-G motif; other site
550537019024	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
550537019025	anchoring element; other site
550537019026	dimer interface [polypeptide binding]; other site
550537019027	ATP binding site [chemical binding]; other site
550537019028	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
550537019029	active site
550537019030	putative metal-binding site [ion binding]; other site
550537019031	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
550537019032	HMMPfam hit to PF00986, DNA topoisomerase, type IIA, subunit B, C-terminal, score 9.9e-47
550537019033	HMMPfam hit to PF01751, TOPRIM, score 1.1e-05
550537019034	PS00177 DNA topoisomerase II signature.
550537019035	HMMPfam hit to PF00204, DNA topoisomerase, type IIA, subunit B, region 2, score 6.8e-97
550537019036	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.3e-32
550537019037	recF protein; Region: recf; TIGR00611
550537019038	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537019039	Walker A/P-loop; other site
550537019040	ATP binding site [chemical binding]; other site
550537019041	Q-loop/lid; other site
550537019042	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537019043	ABC transporter signature motif; other site
550537019044	Walker B; other site
550537019045	D-loop; other site
550537019046	H-loop/switch region; other site
550537019047	HMMPfam hit to PF02463, SMC protein, N-terminal, score 1.1e-60
550537019048	PS00618 RecF protein signature 2.
550537019049	PS00617 RecF protein signature 1.
550537019050	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019051	DNA polymerase III subunit beta; Validated; Region: PRK05643
550537019052	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
550537019053	putative DNA binding surface [nucleotide binding]; other site
550537019054	dimer interface [polypeptide binding]; other site
550537019055	beta-clamp/clamp loader binding surface; other site
550537019056	beta-clamp/translesion DNA polymerase binding surface; other site
550537019057	HMMPfam hit to PF02768, DNA polymerase III, beta chain, score 1.7e-62
550537019058	HMMPfam hit to PF02767, DNA polymerase III, beta chain, score 7.4e-70
550537019059	HMMPfam hit to PF00712, DNA polymerase III, beta chain, score 3.5e-68
550537019060	DnaA N-terminal domain; Region: DnaA_N; pfam11638
550537019061	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
550537019062	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537019063	Walker A motif; other site
550537019064	ATP binding site [chemical binding]; other site
550537019065	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
550537019066	Walker B motif; other site
550537019067	arginine finger; other site
550537019068	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
550537019069	DnaA box-binding interface [nucleotide binding]; other site
550537019070	HMMPfam hit to PF08299, Chromosomal replication initiator, DnaA C-terminal, score 2.1e-48
550537019071	PS01008 DnaA protein signature.
550537019072	HMMPfam hit to PF00308, Chromosomal replication initiator, DnaA, score 2.8e-152
550537019073	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019074	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
550537019075	HMMPfam hit to PF00468, Ribosomal protein L34, score 7e-22
550537019076	PS00784 Ribosomal protein L34 signature.
550537019077	ribonuclease P; Reviewed; Region: rnpA; PRK01732
550537019078	HMMPfam hit to PF00825, Bacterial ribonuclease P protein, score 1.3e-60
550537019079	PS00648 Bacterial ribonuclease P protein component signature.
550537019080	hypothetical protein; Validated; Region: PRK00041
550537019081	HMMPfam hit to PF01809, Protein of unknown function DUF37, score 6.8e-49
550537019082	membrane protein insertase; Provisional; Region: PRK01318
550537019083	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
550537019084	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
550537019085	4 probable transmembrane helices predicted for SEN3659 by TMHMM2.0 at aa 7-24, 346-368, 419-441 and 497-519
550537019086	HMMPfam hit to PF02096, 60 kDa inner membrane insertion protein, score 3.7e-124
550537019087	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
550537019088	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
550537019089	trmE is a tRNA modification GTPase; Region: trmE; cd04164
550537019090	G1 box; other site
550537019091	GTP/Mg2+ binding site [chemical binding]; other site
550537019092	Switch I region; other site
550537019093	G2 box; other site
550537019094	Switch II region; other site
550537019095	G3 box; other site
550537019096	G4 box; other site
550537019097	G5 box; other site
550537019098	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
550537019099	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 6.2e-43
550537019100	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019101	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
550537019102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537019103	putative substrate translocation pore; other site
550537019104	12 probable transmembrane helices predicted for SEN3661 by TMHMM2.0 at aa 5-24, 39-58, 70-89, 99-116, 129-151, 156-178, 210-232, 242-264, 271-290, 294-316, 328-350 and 355-377
550537019105	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 7.6e-44
550537019106	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019107	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
550537019108	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537019109	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
550537019110	substrate binding pocket [chemical binding]; other site
550537019111	dimerization interface [polypeptide binding]; other site
550537019112	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 4.3e-16
550537019113	PS00044 Bacterial regulatory proteins, lysR family signature.
550537019114	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.6e-07
550537019115	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
550537019116	Predicted flavoprotein [General function prediction only]; Region: COG0431
550537019117	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
550537019118	HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 7.7e-63
550537019119	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
550537019120	13 probable transmembrane helices predicted for SEN3665 by TMHMM2.0 at aa 30-52, 62-84, 86-108, 113-135, 142-161, 176-198, 205-222, 253-275, 295-317, 327-349, 356-374, 389-411 and 424-442
550537019121	HMMPfam hit to PF00860, Xanthine/uracil/vitamin C permease, score 1.3e-29
550537019122	PS00267 Tachykinin family signature.
550537019123	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
550537019124	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537019125	active site
550537019126	motif I; other site
550537019127	motif II; other site
550537019128	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 2.6e-25
550537019129	transcriptional regulator PhoU; Provisional; Region: PRK11115
550537019130	PhoU domain; Region: PhoU; pfam01895
550537019131	PhoU domain; Region: PhoU; pfam01895
550537019132	HMMPfam hit to PF01895, PhoU, score 5.8e-31
550537019133	HMMPfam hit to PF01895, PhoU, score 1.1e-32
550537019134	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
550537019135	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
550537019136	Walker A/P-loop; other site
550537019137	ATP binding site [chemical binding]; other site
550537019138	Q-loop/lid; other site
550537019139	ABC transporter signature motif; other site
550537019140	Walker B; other site
550537019141	D-loop; other site
550537019142	H-loop/switch region; other site
550537019143	HMMPfam hit to PF00005, ABC transporter related, score 8.5e-72
550537019144	PS00211 ABC transporters family signature.
550537019145	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019146	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
550537019147	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537019148	dimer interface [polypeptide binding]; other site
550537019149	conserved gate region; other site
550537019150	putative PBP binding loops; other site
550537019151	ABC-ATPase subunit interface; other site
550537019152	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 1.2e-39
550537019153	6 probable transmembrane helices predicted for SEN3669 by TMHMM2.0 at aa 29-51, 88-110, 123-145, 150-169, 201-223 and 268-290
550537019154	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537019155	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
550537019156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537019157	dimer interface [polypeptide binding]; other site
550537019158	conserved gate region; other site
550537019159	putative PBP binding loops; other site
550537019160	ABC-ATPase subunit interface; other site
550537019161	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 4.2e-09
550537019162	6 probable transmembrane helices predicted for SEN3670 by TMHMM2.0 at aa 21-43, 78-100, 112-134, 166-188, 227-249 and 282-304
550537019163	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537019164	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537019165	substrate binding pocket [chemical binding]; other site
550537019166	membrane-bound complex binding site; other site
550537019167	hinge residues; other site
550537019168	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 4.7e-35
550537019169	1 probable transmembrane helix predicted for SEN3671 by TMHMM2.0 at aa 7-29
550537019170	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
550537019171	active site
550537019172	P-loop; other site
550537019173	phosphorylation site [posttranslational modification]
550537019174	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
550537019175	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
550537019176	9 probable transmembrane helices predicted for SEN3672 by TMHMM2.0 at aa 134-156, 166-188, 201-223, 245-267, 279-301, 324-346, 359-381, 396-418 and 430-448
550537019177	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 5.3e-11
550537019178	HMMPfam hit to PF02379, Phosphotransferase system, fructose-specific IIB subunit, score 5.8e-57
550537019179	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
550537019180	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
550537019181	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
550537019182	shikimate binding site; other site
550537019183	NAD(P) binding site [chemical binding]; other site
550537019184	HMMPfam hit to PF01488, Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase, score 2e-08
550537019185	HMMPfam hit to PF08501, Shikimate dehydrogenase substrate binding, N-terminal, score 9.7e-26
550537019186	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
550537019187	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
550537019188	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
550537019189	HMMPfam hit to PF00496, Bacterial extracellular solute-binding protein, family 5, score 5.1e-30
550537019190	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
550537019191	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
550537019192	glutaminase active site [active]
550537019193	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
550537019194	dimer interface [polypeptide binding]; other site
550537019195	active site
550537019196	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
550537019197	dimer interface [polypeptide binding]; other site
550537019198	active site
550537019199	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 3.2e-38
550537019200	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 3.1e-43
550537019201	HMMPfam hit to PF00310, Glutamine amidotransferase, class-II, score 1e-62
550537019202	PS00443 Glutamine amidotransferases class-II active site.
550537019203	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
550537019204	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
550537019205	Substrate binding site; other site
550537019206	Mg++ binding site; other site
550537019207	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
550537019208	active site
550537019209	substrate binding site [chemical binding]; other site
550537019210	CoA binding site [chemical binding]; other site
550537019211	PS00101 Hexapeptide-repeat containing-transferases signature.
550537019212	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 2.6
550537019213	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 14
550537019214	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 2.1
550537019215	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 22
550537019216	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.056
550537019217	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 5.9
550537019218	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 0.063
550537019219	HMMPfam hit to PF01128, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, score 2.6e-08
550537019220	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
550537019221	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
550537019222	6 probable transmembrane helices predicted for SEN3677 by TMHMM2.0 at aa 25-47, 62-81, 94-116, 120-142, 158-192 and 207-229
550537019223	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
550537019224	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
550537019225	gamma subunit interface [polypeptide binding]; other site
550537019226	epsilon subunit interface [polypeptide binding]; other site
550537019227	LBP interface [polypeptide binding]; other site
550537019228	HMMPfam hit to PF00401, ATPase, F1 complex, delta/epsilon subunit, score 1.4e-12
550537019229	HMMPfam hit to PF02823, ATPase, F1 complex, delta/epsilon subunit, score 2.3e-39
550537019230	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
550537019231	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
550537019232	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
550537019233	alpha subunit interaction interface [polypeptide binding]; other site
550537019234	Walker A motif; other site
550537019235	ATP binding site [chemical binding]; other site
550537019236	Walker B motif; other site
550537019237	inhibitor binding site; inhibition site
550537019238	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
550537019239	HMMPfam hit to PF00306, ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal, score 1.7e-53
550537019240	HMMPfam hit to PF00006, ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding, score 4.5e-95
550537019241	PS00152 ATP synthase alpha and beta subunits signature.
550537019242	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019243	HMMPfam hit to PF02874, ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal, score 1.1e-25
550537019244	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
550537019245	core domain interface [polypeptide binding]; other site
550537019246	delta subunit interface [polypeptide binding]; other site
550537019247	epsilon subunit interface [polypeptide binding]; other site
550537019248	HMMPfam hit to PF00231, ATPase, F1 complex, gamma subunit, score 3.7e-178
550537019249	PS00153 ATP synthase gamma subunit signature.
550537019250	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
550537019251	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
550537019252	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
550537019253	beta subunit interaction interface [polypeptide binding]; other site
550537019254	Walker A motif; other site
550537019255	ATP binding site [chemical binding]; other site
550537019256	Walker B motif; other site
550537019257	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
550537019258	HMMPfam hit to PF00306, ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal, score 1.2e-29
550537019259	HMMPfam hit to PF00006, ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding, score 8e-120
550537019260	PS00152 ATP synthase alpha and beta subunits signature.
550537019261	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019262	HMMPfam hit to PF02874, ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal, score 3.1e-16
550537019263	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
550537019264	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
550537019265	HMMPfam hit to PF00213, ATPase, F1 complex, OSCP/delta subunit, score 6.1e-77
550537019266	PS00389 ATP synthase delta (OSCP) subunit signature.
550537019267	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
550537019268	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
550537019269	HMMPfam hit to PF00430, ATPase, F0 complex, subunit B/B', bacterial and chloroplast, score 1e-43
550537019270	1 probable transmembrane helix predicted for SEN3683 by TMHMM2.0 at aa 5-27
550537019271	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
550537019272	HMMPfam hit to PF00137, ATPase, F0/V0 complex, subunit C, score 1.2e-24
550537019273	2 probable transmembrane helices predicted for SEN3684 by TMHMM2.0 at aa 10-32 and 53-75
550537019274	PS00605 ATP synthase c subunit signature.
550537019275	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
550537019276	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
550537019277	HMMPfam hit to PF00119, ATPase, F0 complex, subunit A, score 3e-95
550537019278	5 probable transmembrane helices predicted for SEN3685 by TMHMM2.0 at aa 36-58, 100-122, 142-164, 211-233 and 243-265
550537019279	PS00449 ATP synthase a subunit signature.
550537019280	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
550537019281	HMMPfam hit to PF03899, ATPase, F0 complex, subunit I, proteobacteria-type, score 9.7e-65
550537019282	4 probable transmembrane helices predicted for SEN3686 by TMHMM2.0 at aa 15-31, 36-58, 73-95 and 100-122
550537019283	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
550537019284	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537019285	S-adenosylmethionine binding site [chemical binding]; other site
550537019286	HMMPfam hit to PF02527, Glucose inhibited division protein, score 3.8e-94
550537019287	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
550537019288	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
550537019289	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
550537019290	HMMPfam hit to PF01134, Glucose-inhibited division protein A, score 7.4e-278
550537019291	PS01281 Glucose inhibited division protein A family signature 2.
550537019292	PS01280 Glucose inhibited division protein A family signature 1.
550537019293	FMN-binding protein MioC; Provisional; Region: PRK09004
550537019294	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 9.4e-33
550537019295	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
550537019296	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537019297	putative DNA binding site [nucleotide binding]; other site
550537019298	putative Zn2+ binding site [ion binding]; other site
550537019299	AsnC family; Region: AsnC_trans_reg; pfam01037
550537019300	HMMPfam hit to PF01037, Bacterial regulatory proteins, AsnC/Lrp, score 4.7e-21
550537019301	PS00519 Bacterial regulatory proteins, asnC family signature.
550537019302	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
550537019303	dimer interface [polypeptide binding]; other site
550537019304	active site
550537019305	HMMPfam hit to PF03590, Aspartate--ammonia ligase, score 4.4e-181
550537019306	hypothetical protein; Provisional; Region: yieM; PRK10997
550537019307	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
550537019308	metal ion-dependent adhesion site (MIDAS); other site
550537019309	regulatory ATPase RavA; Provisional; Region: PRK13531
550537019310	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537019311	Walker A motif; other site
550537019312	ATP binding site [chemical binding]; other site
550537019313	Walker B motif; other site
550537019314	arginine finger; other site
550537019315	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
550537019316	HMMPfam hit to PF07728, ATPase associated with various cellular activities, AAA-5, score 9.5e-48
550537019317	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
550537019318	potassium uptake protein; Region: kup; TIGR00794
550537019319	12 probable transmembrane helices predicted for SEN3694 by TMHMM2.0 at aa 7-29, 49-71, 102-124, 134-156, 168-190, 210-232, 245-267, 287-309, 335-357, 363-385, 392-414 and 419-441
550537019320	HMMPfam hit to PF02705, K+ potassium transporter, score 0
550537019321	D-ribose pyranase; Provisional; Region: PRK11797
550537019322	HMMPfam hit to PF05025, RbsD or FucU transport, score 1.4e-87
550537019323	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
550537019324	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
550537019325	Walker A/P-loop; other site
550537019326	ATP binding site [chemical binding]; other site
550537019327	Q-loop/lid; other site
550537019328	ABC transporter signature motif; other site
550537019329	Walker B; other site
550537019330	D-loop; other site
550537019331	H-loop/switch region; other site
550537019332	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
550537019333	HMMPfam hit to PF00005, ABC transporter related, score 1.6e-48
550537019334	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019335	HMMPfam hit to PF00005, ABC transporter related, score 1.4e-30
550537019336	PS00211 ABC transporters family signature.
550537019337	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
550537019338	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
550537019339	TM-ABC transporter signature motif; other site
550537019340	8 probable transmembrane helices predicted for SEN3697 by TMHMM2.0 at aa 21-43, 53-72, 74-93, 97-119, 126-145, 165-187, 221-243 and 275-297
550537019341	HMMPfam hit to PF02653, Bacterial inner-membrane translocator, score 2.6e-72
550537019342	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
550537019343	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
550537019344	ligand binding site [chemical binding]; other site
550537019345	dimerization interface [polypeptide binding]; other site
550537019346	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 1.4e-13
550537019347	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537019348	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
550537019349	substrate binding site [chemical binding]; other site
550537019350	dimer interface [polypeptide binding]; other site
550537019351	ATP binding site [chemical binding]; other site
550537019352	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 1.8e-90
550537019353	PS00583 pfkB family of carbohydrate kinases signature 1.
550537019354	PS00584 pfkB family of carbohydrate kinases signature 2.
550537019355	transcriptional repressor RbsR; Provisional; Region: PRK10423
550537019356	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537019357	DNA binding site [nucleotide binding]
550537019358	domain linker motif; other site
550537019359	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
550537019360	dimerization interface [polypeptide binding]; other site
550537019361	ligand binding site [chemical binding]; other site
550537019362	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 1e-13
550537019363	PS00356 Bacterial regulatory proteins, lacI family signature.
550537019364	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 3.2e-23
550537019366	11 probable transmembrane helices predicted for SEN3701 by TMHMM2.0 at aa 23-45, 57-79, 83-102, 122-139, 143-165, 185-207, 212-234, 246-268, 272-294, 315-337 and 352-371
550537019367	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 9e-46
550537019368	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019369	Signal peptide predicted for SEN3701 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.435 between residues 21 and 22
550537019370	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019371	2 probable transmembrane helices predicted for SEN3702 by TMHMM2.0 at aa 15-37 and 50-72
550537019372	Signal peptide predicted for SEN3702 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.790 between residues 38 and 39
550537019373	Transcriptional regulators [Transcription]; Region: FadR; COG2186
550537019374	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537019375	DNA-binding site [nucleotide binding]; DNA binding site
550537019376	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
550537019377	HMMPfam hit to PF07729, GntR, C-terminal, score 4.7e-30
550537019378	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 2.3e-22
550537019379	PS00043 Bacterial regulatory proteins, gntR family signature.
550537019380	transcriptional regulator HdfR; Provisional; Region: PRK03601
550537019381	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537019382	LysR substrate binding domain; Region: LysR_substrate; pfam03466
550537019383	dimerization interface [polypeptide binding]; other site
550537019384	HMMPfam hit to PF03466, LysR, substrate-binding, score 7.2e-06
550537019385	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 6.5e-20
550537019386	PS00044 Bacterial regulatory proteins, lysR family signature.
550537019387	hypothetical protein; Provisional; Region: PRK11027
550537019388	HMMPfam hit to PF04219, Protein of unknown function DUF413, score 1.1e-48
550537019389	putative ATP-dependent protease; Provisional; Region: PRK09862
550537019390	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
550537019391	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537019392	Walker A motif; other site
550537019393	ATP binding site [chemical binding]; other site
550537019394	Walker B motif; other site
550537019395	arginine finger; other site
550537019396	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
550537019397	HMMPfam hit to PF01078, Magnesium chelatase, ChlI subunit, score 6.1e-138
550537019398	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537019399	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019400	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
550537019401	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
550537019402	PYR/PP interface [polypeptide binding]; other site
550537019403	dimer interface [polypeptide binding]; other site
550537019404	TPP binding site [chemical binding]; other site
550537019405	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
550537019406	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
550537019407	TPP-binding site [chemical binding]; other site
550537019408	dimer interface [polypeptide binding]; other site
550537019409	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-terminal TPP binding region, score 7.6e-105
550537019410	PS00044 Bacterial regulatory proteins, lysR family signature.
550537019411	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central region, score 2.5e-64
550537019412	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-terminal TPP-binding, score 2.3e-77
550537019413	PS00187 Thiamine pyrophosphate enzymes signature.
550537019414	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
550537019415	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
550537019416	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
550537019417	homodimer interface [polypeptide binding]; other site
550537019418	substrate-cofactor binding pocket; other site
550537019419	catalytic residue [active]
550537019420	HMMPfam hit to PF01063, Aminotransferase, class IV, score 3.9e-142
550537019421	PS00770 Aminotransferases class-IV signature.
550537019422	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
550537019423	HMMPfam hit to PF00920, Dihydroxy-acid and 6-phosphogluconate dehydratase, score 0
550537019424	PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.
550537019425	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019426	PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2.
550537019427	threonine dehydratase; Reviewed; Region: PRK09224
550537019428	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
550537019429	tetramer interface [polypeptide binding]; other site
550537019430	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537019431	catalytic residue [active]
550537019432	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
550537019433	putative Ile/Val binding site [chemical binding]; other site
550537019434	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
550537019435	putative Ile/Val binding site [chemical binding]; other site
550537019436	HMMPfam hit to PF00291, Pyridoxal phosphate-dependent enzyme, beta subunit, score 1.5e-105
550537019437	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
550537019438	HMMPfam hit to PF00585, Threonine dehydratase, C-terminal, score 1.5e-49
550537019439	HMMPfam hit to PF00585, Threonine dehydratase, C-terminal, score 1e-46
550537019440	Phage-related protein [Function unknown]; Region: COG4679
550537019441	HMMPfam hit to PF05973, Protein of unknown function DUF891, score 6.6e-26
550537019442	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
550537019443	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537019444	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
550537019445	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
550537019446	putative dimerization interface [polypeptide binding]; other site
550537019447	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.3e-33
550537019448	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 3e-23
550537019449	PS00044 Bacterial regulatory proteins, lysR family signature.
550537019450	ketol-acid reductoisomerase; Validated; Region: PRK05225
550537019451	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
550537019452	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
550537019453	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
550537019454	HMMPfam hit to PF07991, Acetohydroxy acid isomeroreductase, catalytic, score 7.4e-86
550537019455	HMMPfam hit to PF01450, Acetohydroxy acid isomeroreductase C-terminal, score 2.1e-133
550537019456	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
550537019457	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
550537019458	HMMPfam hit to PF00639, Peptidyl-prolyl cis-trans isomerase, PpiC-type, score 9.1e-43
550537019459	PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature.
550537019460	Note by comparing to S. Typhi it appears that the majority of this CDS has been deleted
550537019461	Signal peptide predicted for SEN3717 by SignalP 2.0 HMM (Signal peptide probability 0.790) with cleavage site probability 0.373 between residues 27 and 28
550537019462	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
550537019463	Part of AAA domain; Region: AAA_19; pfam13245
550537019464	Family description; Region: UvrD_C_2; pfam13538
550537019465	HMMPfam hit to PF00580, DNA helicase, UvrD/REP type, score 5.7e-228
550537019466	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019467	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
550537019468	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
550537019469	HMMPfam hit to PF02541, Ppx/GppA phosphatase, score 1.7e-136
550537019470	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019471	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
550537019472	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
550537019473	ATP binding site [chemical binding]; other site
550537019474	Mg++ binding site [ion binding]; other site
550537019475	motif III; other site
550537019476	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537019477	nucleotide binding region [chemical binding]; other site
550537019478	ATP-binding site [chemical binding]; other site
550537019479	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019480	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 4.9e-34
550537019481	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 3.2e-62
550537019482	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
550537019483	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019484	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
550537019485	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
550537019486	catalytic residues [active]
550537019487	HMMPfam hit to PF00085, Thioredoxin domain, score 4e-53
550537019488	PS00194 Thioredoxin family active site.
550537019489	transcription termination factor Rho; Provisional; Region: rho; PRK09376
550537019490	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
550537019491	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
550537019492	RNA binding site [nucleotide binding]; other site
550537019493	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
550537019494	multimer interface [polypeptide binding]; other site
550537019495	Walker A motif; other site
550537019496	ATP binding site [chemical binding]; other site
550537019497	Walker B motif; other site
550537019498	HMMPfam hit to PF07498, Rho termination factor, N-terminal, score 1.1e-20
550537019499	HMMPfam hit to PF07497, Rho termination factor, RNA-binding, score 2.9e-59
550537019500	PS00464 Ribosomal protein L22 signature.
550537019501	HMMPfam hit to PF00006, ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding, score 6.8e-79
550537019502	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019503	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
550537019504	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
550537019505	Mg++ binding site [ion binding]; other site
550537019506	putative catalytic motif [active]
550537019507	substrate binding site [chemical binding]; other site
550537019508	11 probable transmembrane helices predicted for SEN3723 by TMHMM2.0 at aa 5-24, 45-65, 69-88, 105-127, 131-153, 160-179, 184-206, 213-232, 242-261, 294-311 and 321-338
550537019509	HMMPfam hit to PF00953, Glycosyl transferase, family 4, score 7.6e-11
550537019510	PS00962 Ribosomal protein S2 signature 1.
550537019511	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
550537019512	Chain length determinant protein; Region: Wzz; pfam02706
550537019513	HMMPfam hit to PF02706, Lipopolysaccharide biosynthesis, score 8.5e-19
550537019514	2 probable transmembrane helices predicted for SEN3724 by TMHMM2.0 at aa 29-51 and 323-342
550537019515	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
550537019516	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
550537019517	active site
550537019518	homodimer interface [polypeptide binding]; other site
550537019519	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 1.8e-199
550537019520	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
550537019521	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
550537019522	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
550537019523	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, N-terminal, score 2.2e-88
550537019524	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, dimerisation, score 8.9e-47
550537019525	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, C-terminal, score 3.6e-29
550537019526	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
550537019527	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
550537019528	NAD binding site [chemical binding]; other site
550537019529	substrate binding site [chemical binding]; other site
550537019530	homodimer interface [polypeptide binding]; other site
550537019531	active site
550537019532	HMMPfam hit to PF01370, NAD-dependent epimerase/dehydratase, score 5.5e-97
550537019533	Note by comparing to S. Typhi it appears that the majority of this CDS has been deleted
550537019534	HMMPfam hit to PF00483, Nucleotidyl transferase, score 9.5e-11
550537019535	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
550537019536	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 5.4e-07
550537019537	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
550537019538	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
550537019539	inhibitor-cofactor binding pocket; inhibition site
550537019540	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537019541	catalytic residue [active]
550537019542	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 1.8e-87
550537019543	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019544	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
550537019545	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
550537019546	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 0.00019
550537019547	12 probable transmembrane helices predicted for SEN3731 by TMHMM2.0 at aa 7-29, 44-66, 79-101, 116-138, 145-167, 177-195, 216-238, 253-275, 296-318, 333-355, 362-384 and 390-412
550537019548	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
550537019549	HMMPfam hit to PF07429, 4-alpha-L-fucosyltransferase, score 5.9e-264
550537019550	putative common antigen polymerase; Provisional; Region: PRK02975
550537019551	HMMPfam hit to PF06899, WzyE, score 0
550537019552	11 probable transmembrane helices predicted for SEN3733 by TMHMM2.0 at aa 4-26, 33-55, 70-89, 116-138, 153-175, 182-201, 205-224, 226-245, 338-360, 381-398 and 408-430
550537019553	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019554	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537019555	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
550537019556	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
550537019557	HMMPfam hit to PF03808, Glycosyl transferase WecB/TagA/CpsF, score 2.5e-93
550537019558	putative transport protein YifK; Provisional; Region: PRK10746
550537019559	HMMPfam hit to PF00324, Amino acid permease-associated region, score 7.9e-127
550537019560	12 probable transmembrane helices predicted for SEN3735 by TMHMM2.0 at aa 19-36, 40-59, 93-115, 125-147, 154-176, 191-213, 240-262, 277-299, 331-353, 358-380, 401-423 and 428-450
550537019561	PS00218 Amino acid permeases signature.
550537019562	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019563	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
550537019564	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019565	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
550537019566	HemY protein N-terminus; Region: HemY_N; pfam07219
550537019567	HMMPfam hit to PF07719, Tetratricopeptide TPR2, score 1.9e-06
550537019568	PS00215 Mitochondrial energy transfer proteins signature.
550537019569	HMMPfam hit to PF07219, HemY, N-terminal, score 3.9e-47
550537019570	1 probable transmembrane helix predicted for SEN3736 by TMHMM2.0 at aa 21-43
550537019571	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
550537019572	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
550537019573	HMMPfam hit to PF04375, HemX, score 2.4e-182
550537019574	1 probable transmembrane helix predicted for SEN3737 by TMHMM2.0 at aa 35-57
550537019575	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
550537019576	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
550537019577	active site
550537019578	HMMPfam hit to PF02602, Tetrapyrrole biosynthesis, uroporphyrinogen III synthase, score 1e-61
550537019579	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
550537019580	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
550537019581	domain interfaces; other site
550537019582	active site
550537019583	HMMPfam hit to PF03900, Tetrapyrrole biosynthesis, hydroxymethylbilane synthase, score 2.5e-34
550537019584	PS00533 Porphobilinogen deaminase cofactor-binding site.
550537019585	HMMPfam hit to PF01379, Tetrapyrrole biosynthesis, hydroxymethylbilane synthase, score 1e-143
550537019586	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
550537019587	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
550537019588	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
550537019589	HMMPfam hit to PF01295, Adenylate cyclase, class-I, score 0
550537019590	PS01092 Adenylate cyclases class-I signature 1.
550537019591	PS01093 Adenylate cyclases class-I signature 2.
550537019592	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
550537019593	putative iron binding site [ion binding]; other site
550537019594	HMMPfam hit to PF01491, Frataxin-like, score 4.5e-73
550537019595	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
550537019596	4 probable transmembrane helices predicted for SEN3742 by TMHMM2.0 at aa 20-42, 47-64, 71-93 and 103-125
550537019597	Comparison with S. Typhi indicates that a deletion event has removed the central portion of this CDS
550537019598	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
550537019599	1 probable transmembrane helix predicted for SEN3743 by TMHMM2.0 at aa 7-29
550537019600	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019601	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
550537019602	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
550537019603	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
550537019604	HMMPfam hit to PF01678, Diaminopimelate epimerase, score 9.3e-56
550537019605	PS01326 Diaminopimelate epimerase signature.
550537019606	HMMPfam hit to PF01678, Diaminopimelate epimerase, score 4.7e-52
550537019607	hypothetical protein; Provisional; Region: PRK10963
550537019608	HMMPfam hit to PF04340, Protein of unknown function DUF484, score 6.8e-114
550537019609	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
550537019610	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
550537019611	active site
550537019612	Int/Topo IB signature motif; other site
550537019613	HMMPfam hit to PF02899, Integrase, N-terminal SAM-like, phage, score 1e-31
550537019614	HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 3e-61
550537019615	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
550537019616	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537019617	motif II; other site
550537019618	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 6.3e-23
550537019619	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
550537019620	Part of AAA domain; Region: AAA_19; pfam13245
550537019621	Family description; Region: UvrD_C_2; pfam13538
550537019622	HMMPfam hit to PF00580, DNA helicase, UvrD/REP type, score 5.7e-234
550537019623	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019624	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
550537019625	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
550537019626	Cl binding site [ion binding]; other site
550537019627	oligomer interface [polypeptide binding]; other site
550537019628	HMMPfam hit to PF01544, Mg2+ transporter protein, CorA-like, score 4.2e-103
550537019629	2 probable transmembrane helices predicted for SEN3749 by TMHMM2.0 at aa 255-273 and 288-310
550537019630	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
550537019631	EamA-like transporter family; Region: EamA; cl17759
550537019632	10 probable transmembrane helices predicted for SEN3750 by TMHMM2.0 at aa 11-33, 38-60, 73-95, 100-122, 129-146, 150-167, 180-197, 212-234, 239-261 and 271-290
550537019633	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2.8e-11
550537019634	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
550537019635	CoenzymeA binding site [chemical binding]; other site
550537019636	subunit interaction site [polypeptide binding]; other site
550537019637	PHB binding site; other site
550537019638	HMMPfam hit to PF03061, Thioesterase superfamily, score 7.8e-16
550537019639	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
550537019640	dimerization interface [polypeptide binding]; other site
550537019641	substrate binding site [chemical binding]; other site
550537019642	active site
550537019643	calcium binding site [ion binding]; other site
550537019644	HMMPfam hit to PF02253, Phospholipase A1, score 6.6e-152
550537019645	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
550537019646	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537019647	ATP binding site [chemical binding]; other site
550537019648	putative Mg++ binding site [ion binding]; other site
550537019649	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
550537019650	nucleotide binding region [chemical binding]; other site
550537019651	ATP-binding site [chemical binding]; other site
550537019652	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
550537019653	Helicase and RNase D C-terminal; Region: HRDC; smart00341
550537019654	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 6.7e-37
550537019655	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019656	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 2e-30
550537019657	HMMPfam hit to PF02008, Zinc finger, CXXC-type, score 0.0001
550537019658	HMMPfam hit to PF00570, Helicase and RNase D C-terminal, HRDC, score 2e-35
550537019659	threonine efflux system; Provisional; Region: PRK10229
550537019660	6 probable transmembrane helices predicted for SEN3754 by TMHMM2.0 at aa 4-26, 42-64, 68-87, 119-141, 151-173 and 186-205
550537019661	HMMPfam hit to PF01810, Lysine exporter protein (LYSE/YGGA), score 4.8e-75
550537019662	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
550537019663	6 probable transmembrane helices predicted for SEN3755 by TMHMM2.0 at aa 5-27, 39-61, 71-88, 115-137, 147-169 and 188-205
550537019664	HMMPfam hit to PF01810, Lysine exporter protein (LYSE/YGGA), score 1.5e-59
550537019665	lysophospholipase L2; Provisional; Region: PRK10749
550537019666	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
550537019667	HMMPfam hit to PF00561, Alpha/beta hydrolase fold-1, score 1.7e-36
550537019668	putative hydrolase; Provisional; Region: PRK10976
550537019669	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537019670	active site
550537019671	motif I; other site
550537019672	motif II; other site
550537019673	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537019674	PS01228 Hypothetical cof family signature 1.
550537019675	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 3.8e-87
550537019676	PS01229 Hypothetical cof family signature 2.
550537019677	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
550537019678	EamA-like transporter family; Region: EamA; pfam00892
550537019679	10 probable transmembrane helices predicted for SEN3758 by TMHMM2.0 at aa 2-24, 28-47, 54-76, 80-102, 109-128, 138-157, 170-192, 202-224, 231-253 and 258-275
550537019680	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2e-07
550537019681	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
550537019682	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537019683	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
550537019684	putative dimerization interface [polypeptide binding]; other site
550537019685	HMMPfam hit to PF03466, LysR, substrate-binding, score 2.4e-44
550537019686	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 6.5e-17
550537019687	PS00044 Bacterial regulatory proteins, lysR family signature.
550537019688	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
550537019689	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
550537019690	THF binding site; other site
550537019691	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
550537019692	substrate binding site [chemical binding]; other site
550537019693	THF binding site; other site
550537019694	zinc-binding site [ion binding]; other site
550537019695	HMMPfam hit to PF08267, Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal, score 1.4e-197
550537019696	HMMPfam hit to PF01717, Methionine synthase, vitamin-B12 independent, score 3.3e-230
550537019697	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
550537019698	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537019699	FeS/SAM binding site; other site
550537019700	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
550537019701	HMMPfam hit to PF04055, Radical SAM, score 1.3e-19
550537019702	HMMPfam hit to PF02810, SEC-C motif, score 1.2e-05
550537019703	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
550537019704	HMMPfam hit to PF01738, Dienelactone hydrolase, score 9.7e-108
550537019705	uridine phosphorylase; Provisional; Region: PRK11178
550537019706	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
550537019707	HMMPfam hit to PF01048, Nucleoside phosphorylase, score 2.5e-110
550537019708	PS01232 Purine and other phosphorylases family 1 signature.
550537019709	DNA recombination protein RmuC; Provisional; Region: PRK10361
550537019710	RmuC family; Region: RmuC; pfam02646
550537019711	1 probable transmembrane helix predicted for SEN3764 by TMHMM2.0 at aa 5-24
550537019712	HMMPfam hit to PF02646, RmuC, score 1.3e-156
550537019713	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
550537019714	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537019715	S-adenosylmethionine binding site [chemical binding]; other site
550537019716	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
550537019717	HMMPfam hit to PF01209, UbiE/COQ5 methyltransferase, score 5.7e-179
550537019718	PS01183 ubiE/COQ5 methyltransferase family signature 1.
550537019719	PS01184 ubiE/COQ5 methyltransferase family signature 2.
550537019720	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
550537019721	SCP-2 sterol transfer family; Region: SCP2; pfam02036
550537019722	HMMPfam hit to PF06843, Protein of unknown function DUF1243, score 4.3e-92
550537019723	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
550537019724	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
550537019725	HMMPfam hit to PF03109, ABC-1, score 1.1e-56
550537019726	1 probable transmembrane helix predicted for SEN3767 by TMHMM2.0 at aa 523-542
550537019727	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
550537019728	HMMPfam hit to PF02416, Bacterial sec-independent translocation protein mttA/Hcf106, score 8.4e-13
550537019729	1 probable transmembrane helix predicted for SEN3768 by TMHMM2.0 at aa 4-21
550537019730	sec-independent translocase; Provisional; Region: PRK01770
550537019731	sec-independent translocase; Provisional; Region: tatB; PRK00404
550537019732	HMMPfam hit to PF02416, Bacterial sec-independent translocation protein mttA/Hcf106, score 0.00059
550537019733	1 probable transmembrane helix predicted for SEN3769 by TMHMM2.0 at aa 4-21
550537019734	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
550537019735	HMMPfam hit to PF00902, Sec-independent periplasmic protein translocase, score 1.4e-98
550537019736	6 probable transmembrane helices predicted for SEN3770 by TMHMM2.0 at aa 20-42, 74-96, 116-138, 158-180, 193-210 and 215-237
550537019737	PS01218 Uncharacterized protein family UPF0032 signature.
550537019738	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
550537019739	active site
550537019740	HMMPfam hit to PF01026, Deoxyribonuclease, TatD-related, score 4.2e-110
550537019741	PS01090 Uncharacterized protein family UPF0006 signature 2.
550537019742	PS01091 Uncharacterized protein family UPF0006 signature 3.
550537019743	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
550537019744	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
550537019745	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
550537019746	HMMPfam hit to PF02357, Transcription antitermination protein, NusG, N-terminal, score 3.6e-30
550537019747	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
550537019748	HMMPfam hit to PF01977, Carboxylyase-related, score 1.1e-249
550537019749	FMN reductase; Validated; Region: fre; PRK08051
550537019750	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
550537019751	FAD binding pocket [chemical binding]; other site
550537019752	FAD binding motif [chemical binding]; other site
550537019753	phosphate binding motif [ion binding]; other site
550537019754	beta-alpha-beta structure motif; other site
550537019755	NAD binding pocket [chemical binding]; other site
550537019756	HMMPfam hit to PF00970, Oxidoreductase FAD-binding region, score 3.8e-13
550537019757	HMMPfam hit to PF00175, Oxidoreductase FAD/NAD(P)-binding, score 2.3e-31
550537019758	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
550537019759	HMMPfam hit to PF05935, Arylsulphotransferase, score 0
550537019760	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
550537019761	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
550537019762	dimer interface [polypeptide binding]; other site
550537019763	active site
550537019764	HMMPfam hit to PF02803, Thiolase, score 9.3e-93
550537019765	PS00099 Thiolases active site.
550537019766	PS00737 Thiolases signature 2.
550537019767	HMMPfam hit to PF00108, Thiolase, score 3.3e-144
550537019768	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537019769	PS00098 Thiolases acyl-enzyme intermediate signature.
550537019770	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
550537019771	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
550537019772	substrate binding site [chemical binding]; other site
550537019773	oxyanion hole (OAH) forming residues; other site
550537019774	trimer interface [polypeptide binding]; other site
550537019775	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
550537019776	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
550537019777	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
550537019778	HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 2.9e-05
550537019779	HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 1.2e-35
550537019780	PS00067 3-hydroxyacyl-CoA dehydrogenase signature.
550537019781	HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD-binding, score 6.8e-86
550537019782	HMMPfam hit to PF00378, Crotonase, core, score 2e-87
550537019783	PS00166 Enoyl-CoA hydratase/isomerase signature.
550537019784	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019785	proline dipeptidase; Provisional; Region: PRK13607
550537019786	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
550537019787	active site
550537019788	HMMPfam hit to PF00557, Peptidase M24, catalytic core, score 1e-107
550537019789	PS00491 Aminopeptidase P and proline dipeptidase signature.
550537019790	hypothetical protein; Provisional; Region: PRK11568
550537019791	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
550537019792	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
550537019793	HMMPfam hit to PF01205, Protein of unknown function UPF0029, N-terminal, score 3.1e-63
550537019794	PS00910 Uncharacterized protein family UPF0029 signature.
550537019795	HMMPfam hit to PF09186, Region of unknown function DUF1949, score 4.8e-19
550537019796	potassium transporter; Provisional; Region: PRK10750
550537019797	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
550537019798	10 probable transmembrane helices predicted for SEN3780 by TMHMM2.0 at aa 9-31, 35-57, 69-91, 133-155, 185-207, 238-260, 273-295, 332-354, 396-418 and 456-478
550537019799	HMMPfam hit to PF02386, Cation transporter, score 1.8e-121
550537019800	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019801	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019802	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019803	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
550537019804	HMMPfam hit to PF00258, Flavodoxin/nitric oxide synthase, score 0.00021
550537019805	PS00201 Flavodoxin signature.
550537019806	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
550537019807	Walker A motif; other site
550537019808	HMMPfam hit to PF03205, Molybdopterin-guanine dinucleotide biosynthesis MobB region, score 8e-57
550537019809	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019810	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
550537019811	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
550537019812	GTP binding site; other site
550537019813	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
550537019814	HMMPfam hit to PF06288, Protein of unknown function DUF1040, score 6.4e-61
550537019815	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
550537019816	serine/threonine protein kinase; Provisional; Region: PRK11768
550537019817	HMMPfam hit to PF01636, Aminoglycoside phosphotransferase, score 1.1e-40
550537019818	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
550537019819	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
550537019820	catalytic residues [active]
550537019821	hinge region; other site
550537019822	alpha helical domain; other site
550537019823	HMMPfam hit to PF01323, DSBA oxidoreductase, score 1.9e-55
550537019824	PS00194 Thioredoxin family active site.
550537019825	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
550537019826	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
550537019827	putative acyl-acceptor binding pocket; other site
550537019828	HMMPfam hit to PF01553, Phospholipid/glycerol acyltransferase, score 7.6e-32
550537019829	3 probable transmembrane helices predicted for SEN3787 by TMHMM2.0 at aa 12-34, 49-66 and 122-140
550537019830	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019831	DNA polymerase I; Provisional; Region: PRK05755
550537019832	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
550537019833	active site
550537019834	metal binding site 1 [ion binding]; metal-binding site
550537019835	putative 5' ssDNA interaction site; other site
550537019836	metal binding site 3; metal-binding site
550537019837	metal binding site 2 [ion binding]; metal-binding site
550537019838	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
550537019839	putative DNA binding site [nucleotide binding]; other site
550537019840	putative metal binding site [ion binding]; other site
550537019841	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
550537019842	active site
550537019843	catalytic site [active]
550537019844	substrate binding site [chemical binding]; other site
550537019845	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
550537019846	active site
550537019847	DNA binding site [nucleotide binding]
550537019848	catalytic site [active]
550537019849	HMMPfam hit to PF02739, 5'-3' exonuclease, score 2.1e-94
550537019850	HMMPfam hit to PF01367, 5'-3' exonuclease, score 2.8e-53
550537019851	HMMPfam hit to PF01612, 3'-5' exonuclease, score 3.3e-70
550537019852	HMMPfam hit to PF00476, DNA-directed DNA polymerase, score 2.9e-234
550537019853	PS00447 DNA polymerase family A signature.
550537019854	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
550537019855	G1 box; other site
550537019856	GTP/Mg2+ binding site [chemical binding]; other site
550537019857	Switch I region; other site
550537019858	G2 box; other site
550537019859	G3 box; other site
550537019860	Switch II region; other site
550537019861	G4 box; other site
550537019862	G5 box; other site
550537019863	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 3.6e-28
550537019864	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019865	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
550537019866	HMMPfam hit to PF04220, Protein of unknown function DUF414, score 5.7e-86
550537019867	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
550537019868	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537019869	FeS/SAM binding site; other site
550537019870	HemN C-terminal domain; Region: HemN_C; pfam06969
550537019871	HMMPfam hit to PF04055, Radical SAM, score 2.7e-24
550537019872	HMMPfam hit to PF06969, HemN, C-terminal, score 2.3e-55
550537019873	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
550537019874	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537019875	active site
550537019876	phosphorylation site [posttranslational modification]
550537019877	intermolecular recognition site; other site
550537019878	dimerization interface [polypeptide binding]; other site
550537019879	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537019880	Walker A motif; other site
550537019881	ATP binding site [chemical binding]; other site
550537019882	Walker B motif; other site
550537019883	arginine finger; other site
550537019884	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
550537019885	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 9.5e-17
550537019886	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537019887	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 4.7e-147
550537019888	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537019889	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537019890	HMMPfam hit to PF00072, Response regulator receiver, score 5.1e-43
550537019891	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
550537019892	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
550537019893	putative active site [active]
550537019894	heme pocket [chemical binding]; other site
550537019895	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537019896	dimer interface [polypeptide binding]; other site
550537019897	phosphorylation site [posttranslational modification]
550537019898	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537019899	ATP binding site [chemical binding]; other site
550537019900	Mg2+ binding site [ion binding]; other site
550537019901	G-X-G motif; other site
550537019902	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 3.7e-32
550537019903	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.5e-14
550537019904	HMMPfam hit to PF08448, PAS fold-4, score 0.00012
550537019905	glutamine synthetase; Provisional; Region: glnA; PRK09469
550537019906	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
550537019907	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
550537019908	PS00182 Glutamine synthetase class-I adenylation site.
550537019909	HMMPfam hit to PF00120, Glutamine synthetase, catalytic region, score 1.5e-179
550537019910	PS00181 Glutamine synthetase  ATP-binding region signature.
550537019911	HMMPfam hit to PF03951, Glutamine synthetase, beta-Grasp, score 1.3e-49
550537019912	PS00180 Glutamine synthetase signature 1.
550537019913	GTP-binding protein; Provisional; Region: PRK10218
550537019914	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
550537019915	G1 box; other site
550537019916	putative GEF interaction site [polypeptide binding]; other site
550537019917	GTP/Mg2+ binding site [chemical binding]; other site
550537019918	Switch I region; other site
550537019919	G2 box; other site
550537019920	G3 box; other site
550537019921	Switch II region; other site
550537019922	G4 box; other site
550537019923	G5 box; other site
550537019924	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
550537019925	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
550537019926	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 3.5e-74
550537019927	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019928	PS00301 GTP-binding elongation factors signature.
550537019929	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 3.4e-14
550537019930	HMMPfam hit to PF00679, Translation elongation factor EFG/EF2, C-terminal, score 1.8e-19
550537019931	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537019932	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
550537019933	active site
550537019934	motif I; other site
550537019935	motif II; other site
550537019936	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537019937	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 4.8e-85
550537019938	PS01229 Hypothetical cof family signature 2.
550537019939	PS01228 Hypothetical cof family signature 1.
550537019940	coproporphyrinogen III oxidase; Validated; Region: PRK08208
550537019941	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537019942	FeS/SAM binding site; other site
550537019943	HemN C-terminal domain; Region: HemN_C; pfam06969
550537019944	HMMPfam hit to PF06969, HemN, C-terminal, score 0.0012
550537019945	HMMPfam hit to PF04055, Radical SAM, score 2e-18
550537019946	Sulfatase; Region: Sulfatase; cl17466
550537019947	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019948	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
550537019949	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
550537019950	Leucine-rich repeats; other site
550537019951	Substrate binding site [chemical binding]; other site
550537019952	outer membrane porin L; Provisional; Region: ompL; PRK09980
550537019953	HMMPfam hit to PF06178, Oligogalacturonate-specific porin, score 1.7e-116
550537019954	Carries a frameshift mutation following codon 277
550537019955	4 probable transmembrane helices predicted for SEN3804 by TMHMM2.0 at aa 23-42, 47-69, 99-121 and 134-156
550537019956	7 probable transmembrane helices predicted for SEN3805 by TMHMM2.0 at aa 20-42, 52-74, 86-108, 119-141, 154-176, 186-208 and 239-261
550537019957	PS00872 Sodium:galactoside symporter family signature.
550537019958	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
550537019959	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
550537019960	11 probable transmembrane helices predicted for SEN3806 by TMHMM2.0 at aa 46-68, 89-111, 121-143, 156-178, 188-210, 244-266, 276-295, 308-328, 333-355, 387-409 and 419-441
550537019961	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019962	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 4e-07
550537019963	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019964	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019965	PS00872 Sodium:galactoside symporter family signature.
550537019966	alpha-glucosidase; Provisional; Region: PRK10426
550537019967	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
550537019968	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
550537019969	putative active site [active]
550537019970	putative catalytic site [active]
550537019971	HMMPfam hit to PF01055, Glycoside hydrolase, family 31, score 3.3e-114
550537019972	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
550537019973	active site
550537019974	catalytic residues [active]
550537019975	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537019976	HMMPfam hit to PF01263, Aldose 1-epimerase, score 4.8e-64
550537019977	PS00017 ATP/GTP-binding site motif A (P-loop).
550537019978	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
550537019979	dimerization interface [polypeptide binding]; other site
550537019980	putative active cleft [active]
550537019981	HMMPfam hit to PF07221, N-acylglucosamine 2-epimerase, score 1.4e-193
550537019982	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
550537019983	HMMPfam hit to PF01791, Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase, score 4.6e-81
550537019984	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
550537019985	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
550537019986	HMMPfam hit to PF03446, 6-phosphogluconate dehydrogenase, NAD-binding, score 5e-66
550537019987	PS00895 3-hydroxyisobutyrate dehydrogenase signature.
550537019988	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537019989	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
550537019990	substrate binding site [chemical binding]; other site
550537019991	ATP binding site [chemical binding]; other site
550537019992	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 4.1e-72
550537019993	PS00584 pfkB family of carbohydrate kinases signature 2.
550537019994	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537019995	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
550537019996	putative DNA binding site [nucleotide binding]; other site
550537019997	putative Zn2+ binding site [ion binding]; other site
550537019998	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537019999	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 2e-25
550537020000	PS00894 Bacterial regulatory proteins, deoR family signature.
550537020001	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 4.1e-77
550537020002	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
550537020003	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537020004	motif II; other site
550537020005	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 2.4e-16
550537020006	hypothetical protein; Reviewed; Region: PRK01637
550537020007	HMMPfam hit to PF03631, Ribonuclease BN, score 7.8e-77
550537020008	6 probable transmembrane helices predicted for SEN3815 by TMHMM2.0 at aa 39-61, 101-120, 141-163, 183-200, 212-234 and 244-266
550537020009	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
550537020010	putative active site [active]
550537020011	dimerization interface [polypeptide binding]; other site
550537020012	putative tRNAtyr binding site [nucleotide binding]; other site
550537020013	HMMPfam hit to PF02580, D-tyrosyl-tRNA(Tyr) deacylase, score 8.5e-92
550537020014	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537020015	Coenzyme A binding pocket [chemical binding]; other site
550537020016	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
550537020017	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 3.2e-16
550537020018	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537020019	non-specific DNA binding site [nucleotide binding]; other site
550537020020	salt bridge; other site
550537020021	sequence-specific DNA binding site [nucleotide binding]; other site
550537020022	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 7.1e-09
550537020023	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
550537020024	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
550537020025	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
550537020026	HMMPfam hit to PF07859, Alpha/beta hydrolase fold-3, score 4.5e-93
550537020027	PS01174 Lipolytic enzymes G-D-X-G family,  serine active site.
550537020028	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
550537020029	Predicted transcriptional regulator [Transcription]; Region: COG2944
550537020030	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537020031	non-specific DNA binding site [nucleotide binding]; other site
550537020032	salt bridge; other site
550537020033	sequence-specific DNA binding site [nucleotide binding]; other site
550537020034	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 2.5e-08
550537020035	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
550537020036	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
550537020037	HMMPfam hit to PF04216, Formate dehydrogenase accessory protein, score 1.6e-207
550537020038	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
550537020039	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
550537020040	HMMPfam hit to PF01292, Cytochrome B561, bacterial, score 0.00041
550537020041	4 probable transmembrane helices predicted for SEN3824 by TMHMM2.0 at aa 21-40, 55-77, 114-136 and 151-173
550537020042	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
550537020043	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
550537020044	HMMPfam hit to PF09163, Formate dehydrogenase, transmembrane, score 6.2e-25
550537020045	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 3.2e-05
550537020046	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537020047	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
550537020048	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
550537020049	[4Fe-4S] binding site [ion binding]; other site
550537020050	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
550537020051	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
550537020052	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
550537020053	molybdopterin cofactor binding site; other site
550537020054	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 2e-17
550537020055	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 2.9e-34
550537020056	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 5e-22
550537020057	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
550537020058	HMMPfam hit to PF02634, Formate dehydrogenase, subunit FdhD, score 1.8e-140
550537020060	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020061	Signal peptide predicted for SEN3829 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.995 between residues 21 and 22
550537020062	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
550537020063	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
550537020064	4 probable transmembrane helices predicted for SEN3831 by TMHMM2.0 at aa 4-26, 38-60, 65-82 and 87-106
550537020065	HMMPfam hit to PF05437, Branched-chain amino acid transport, score 3.9e-18
550537020066	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
550537020067	5 probable transmembrane helices predicted for SEN3832 by TMHMM2.0 at aa 21-43, 58-80, 127-149, 159-178 and 191-213
550537020068	HMMPfam hit to PF03591, AzlC-like, score 1.1e-42
550537020069	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
550537020070	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537020071	non-specific DNA binding site [nucleotide binding]; other site
550537020072	salt bridge; other site
550537020073	sequence-specific DNA binding site [nucleotide binding]; other site
550537020074	Cupin domain; Region: Cupin_2; cl17218
550537020075	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 4.5e-13
550537020076	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020077	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 0.0017
550537020078	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
550537020079	HMMPfam hit to PF05336, Rhamnose mutarotase, score 6.8e-58
550537020080	lactaldehyde reductase; Region: lactal_redase; TIGR02638
550537020081	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
550537020082	dimer interface [polypeptide binding]; other site
550537020083	active site
550537020084	metal binding site [ion binding]; metal-binding site
550537020085	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 5.8e-153
550537020086	PS00060 Iron-containing alcohol dehydrogenases signature 2.
550537020087	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537020088	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
550537020089	intersubunit interface [polypeptide binding]; other site
550537020090	active site
550537020091	Zn2+ binding site [ion binding]; other site
550537020092	HMMPfam hit to PF00596, Class II aldolase/adducin, N-terminal, score 2.1e-29
550537020093	L-rhamnose isomerase; Provisional; Region: PRK01076
550537020094	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
550537020095	HMMPfam hit to PF06134, Rhamnose isomerase, score 0
550537020096	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
550537020097	N- and C-terminal domain interface [polypeptide binding]; other site
550537020098	active site
550537020099	putative catalytic site [active]
550537020100	metal binding site [ion binding]; metal-binding site
550537020101	ATP binding site [chemical binding]; other site
550537020102	rhamnulokinase; Provisional; Region: rhaB; PRK10640
550537020103	carbohydrate binding site [chemical binding]; other site
550537020104	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020105	HMMPfam hit to PF00370, Carbohydrate kinase, FGGY, score 4.5e-15
550537020106	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020107	transcriptional activator RhaS; Provisional; Region: PRK13503
550537020108	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
550537020109	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537020110	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537020111	HMMPfam hit to PF02311, AraC protein, arabinose-binding/dimerisation, score 8.9e-26
550537020112	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.5e-07
550537020113	PS00041 Bacterial regulatory proteins, araC family signature.
550537020114	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 7.9e-14
550537020115	transcriptional activator RhaR; Provisional; Region: PRK13502
550537020116	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
550537020117	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537020118	HMMPfam hit to PF02311, AraC protein, arabinose-binding/dimerisation, score 1.1e-21
550537020119	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.00068
550537020120	PS00041 Bacterial regulatory proteins, araC family signature.
550537020121	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.8e-13
550537020122	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
550537020123	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
550537020124	HMMPfam hit to PF06379, RhaT l-rhamnose-proton symport 2, score 4.1e-298
550537020125	10 probable transmembrane helices predicted for SEN3841 by TMHMM2.0 at aa 4-26, 38-55, 70-92, 99-121, 136-155, 175-192, 212-234, 254-276, 291-309 and 321-343
550537020126	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020127	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
550537020128	HMMPfam hit to PF06178, Oligogalacturonate-specific porin, score 1.3e-117
550537020129	Note appears to have suffered a deletion removing the 5' end of the CDS
550537020130	11 probable transmembrane helices predicted for SEN3843 by TMHMM2.0 at aa 25-47, 67-89, 110-132, 142-164, 185-207, 212-231, 244-266, 276-298, 305-324, 334-356 and 368-390
550537020131	HMMPfam hit to PF06808, TRAP C4-dicarboxylate transport system permease DctM subunit, score 2e-171
550537020132	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020133	PS00070 Aldehyde dehydrogenases cysteine active site.
550537020134	Note appears to have suffered a deletion removing the 3' end of the CDS
550537020135	HMMPfam hit to PF03480, TRAP dicarboxylate transporter- DctP subunit, score 2.9e-16
550537020136	Signal peptide predicted for SEN3844 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.974 between residues 24 and 25
550537020137	superoxide dismutase; Provisional; Region: PRK10925
550537020138	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
550537020139	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
550537020140	HMMPfam hit to PF00081, Manganese and iron superoxide dismutase, score 2.8e-54
550537020141	HMMPfam hit to PF02777, Manganese and iron superoxide dismutase, score 7.6e-70
550537020142	PS00088 Manganese and iron superoxide dismutases signature.
550537020143	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
550537020144	MOSC domain; Region: MOSC; pfam03473
550537020145	3-alpha domain; Region: 3-alpha; pfam03475
550537020146	HMMPfam hit to PF03473, Molybdenum cofactor sulphurase, C-terminal, score 3.4e-44
550537020147	HMMPfam hit to PF03475, Protein of unknown function 3-alpha region, score 5.4e-13
550537020148	SnoaL-like domain; Region: SnoaL_2; pfam12680
550537020149	two-component sensor protein; Provisional; Region: cpxA; PRK09470
550537020150	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537020151	dimerization interface [polypeptide binding]; other site
550537020152	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537020153	dimer interface [polypeptide binding]; other site
550537020154	phosphorylation site [posttranslational modification]
550537020155	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537020156	ATP binding site [chemical binding]; other site
550537020157	Mg2+ binding site [ion binding]; other site
550537020158	G-X-G motif; other site
550537020159	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 9.1e-39
550537020160	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.4e-17
550537020161	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 9.8e-14
550537020162	2 probable transmembrane helices predicted for SEN3848 by TMHMM2.0 at aa 5-27 and 165-187
550537020163	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
550537020164	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537020165	active site
550537020166	intermolecular recognition site; other site
550537020167	dimerization interface [polypeptide binding]; other site
550537020168	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537020169	DNA binding site [nucleotide binding]
550537020170	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 1.7e-22
550537020171	HMMPfam hit to PF00072, Response regulator receiver, score 2.7e-42
550537020172	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
550537020173	dimer interface [polypeptide binding]; other site
550537020174	HMMPfam hit to PF07813, Region of unknown function, Spy-related, score 0.003
550537020175	HMMPfam hit to PF07813, Region of unknown function, Spy-related, score 0.00033
550537020176	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
550537020177	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
550537020178	6 probable transmembrane helices predicted for SEN3851 by TMHMM2.0 at aa 12-34, 38-60, 80-102, 117-139, 158-175 and 180-199
550537020179	HMMPfam hit to PF01545, Cation efflux protein, score 1.8e-109
550537020180	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
550537020181	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
550537020182	active site
550537020183	ADP/pyrophosphate binding site [chemical binding]; other site
550537020184	dimerization interface [polypeptide binding]; other site
550537020185	allosteric effector site; other site
550537020186	fructose-1,6-bisphosphate binding site; other site
550537020187	HMMPfam hit to PF00365, Phosphofructokinase, score 3e-193
550537020188	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020189	PS00433 Phosphofructokinase signature.
550537020190	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
550537020191	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537020192	substrate binding pocket [chemical binding]; other site
550537020193	membrane-bound complex binding site; other site
550537020194	hinge residues; other site
550537020195	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 2.8e-15
550537020196	PS00401 Prokaryotic sulfate-binding proteins signature 1.
550537020197	PS00757 Prokaryotic sulfate-binding proteins signature 2.
550537020198	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
550537020199	HMMPfam hit to PF02611, CDP-diacylglycerol pyrophosphatase, bacterial, score 2.4e-159
550537020200	1 probable transmembrane helix predicted for SEN3854 by TMHMM2.0 at aa 5-23
550537020201	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
550537020202	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
550537020203	11 probable transmembrane helices predicted for SEN3855 by TMHMM2.0 at aa 12-34, 44-66, 79-96, 106-128, 149-171, 176-198, 226-248, 263-285, 317-339, 365-387 and 400-422
550537020204	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5.6e-09
550537020205	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
550537020206	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
550537020207	putative substrate binding site [chemical binding]; other site
550537020208	putative ATP binding site [chemical binding]; other site
550537020209	HMMPfam hit to PF00294, Carbohydrate/purine kinase, score 6.4e-70
550537020210	PS00584 pfkB family of carbohydrate kinases signature 2.
550537020211	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
550537020212	HMMPfam hit to PF03747, ADP-ribosylation/Crystallin J1, score 1.8e-33
550537020213	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020214	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
550537020215	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537020216	DNA-binding site [nucleotide binding]; DNA binding site
550537020217	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
550537020218	UTRA domain; Region: UTRA; pfam07702
550537020219	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 1.2e-13
550537020220	HMMPfam hit to PF07702, UbiC transcription regulator-associated, score 2.1e-26
550537020221	1 probable transmembrane helix predicted for SEN3859 by TMHMM2.0 at aa 20-42
550537020223	HMMPfam hit to PF02611, CDP-diacylglycerol pyrophosphatase, bacterial, score 3.6e-21
550537020224	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
550537020225	HMMPfam hit to PF07883, Cupin 2, conserved barrel, score 5.2e-20
550537020226	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
550537020227	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
550537020228	putative N- and C-terminal domain interface [polypeptide binding]; other site
550537020229	putative active site [active]
550537020230	putative MgATP binding site [chemical binding]; other site
550537020231	catalytic site [active]
550537020232	metal binding site [ion binding]; metal-binding site
550537020233	putative carbohydrate binding site [chemical binding]; other site
550537020234	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
550537020235	HMMPfam hit to PF02782, Carbohydrate kinase, FGGY, score 1.1e-19
550537020236	HMMPfam hit to PF00370, Carbohydrate kinase, FGGY, score 1.1e-46
550537020237	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020238	transcriptional regulator LsrR; Provisional; Region: PRK15418
550537020239	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
550537020240	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
550537020241	HMMPfam hit to PF04198,  sugar-binding region, score 4.6e-85
550537020242	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
550537020243	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
550537020244	Walker A/P-loop; other site
550537020245	ATP binding site [chemical binding]; other site
550537020246	Q-loop/lid; other site
550537020247	ABC transporter signature motif; other site
550537020248	Walker B; other site
550537020249	D-loop; other site
550537020250	H-loop/switch region; other site
550537020251	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
550537020252	HMMPfam hit to PF00005, ABC transporter related, score 3.1e-48
550537020253	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020254	HMMPfam hit to PF00005, ABC transporter related, score 2.8e-28
550537020255	PS00211 ABC transporters family signature.
550537020256	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
550537020257	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
550537020258	TM-ABC transporter signature motif; other site
550537020259	9 probable transmembrane helices predicted for SEN3865 by TMHMM2.0 at aa 13-32, 36-58, 65-87, 91-113, 118-135, 155-177, 210-232, 250-272 and 279-301
550537020260	HMMPfam hit to PF02653, Bacterial inner-membrane translocator, score 6.7e-53
550537020261	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
550537020262	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
550537020263	TM-ABC transporter signature motif; other site
550537020264	9 probable transmembrane helices predicted for SEN3866 by TMHMM2.0 at aa 7-29, 39-61, 66-88, 92-114, 119-141, 161-183, 214-236, 251-282 and 295-314
550537020265	HMMPfam hit to PF02653, Bacterial inner-membrane translocator, score 3.6e-68
550537020266	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020267	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
550537020268	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
550537020269	ligand binding site [chemical binding]; other site
550537020270	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
550537020271	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
550537020272	putative active site; other site
550537020273	catalytic residue [active]
550537020274	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537020275	HMMPfam hit to PF01791, Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase, score 4.3e-16
550537020276	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
550537020277	HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 1.1e-18
550537020278	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
550537020279	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
550537020280	substrate binding site [chemical binding]; other site
550537020281	hexamer interface [polypeptide binding]; other site
550537020282	metal binding site [ion binding]; metal-binding site
550537020283	1 probable transmembrane helix predicted for SEN3870 by TMHMM2.0 at aa 12-34
550537020284	HMMPfam hit to PF00834, Ribulose-phosphate 3-epimerase, score 2e-12
550537020285	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
550537020286	triosephosphate isomerase; Provisional; Region: PRK14567
550537020287	substrate binding site [chemical binding]; other site
550537020288	dimer interface [polypeptide binding]; other site
550537020289	catalytic triad [active]
550537020290	HMMPfam hit to PF00121, Triosephosphate isomerase, score 6e-134
550537020291	PS00171 Triosephosphate isomerase active site.
550537020292	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020293	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
550537020294	HMMPfam hit to PF07305, Protein of unknown function DUF1454, score 1.8e-139
550537020295	Predicted membrane protein [Function unknown]; Region: COG3152
550537020296	HMMPfam hit to PF05656, Protein of unknown function DUF805, score 9.3e-50
550537020297	4 probable transmembrane helices predicted for SEN3873 by TMHMM2.0 at aa 20-37, 41-63, 75-97 and 101-123
550537020298	ferredoxin-NADP reductase; Provisional; Region: PRK10926
550537020299	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
550537020300	FAD binding pocket [chemical binding]; other site
550537020301	FAD binding motif [chemical binding]; other site
550537020302	phosphate binding motif [ion binding]; other site
550537020303	beta-alpha-beta structure motif; other site
550537020304	NAD binding pocket [chemical binding]; other site
550537020305	HMMPfam hit to PF00175, Oxidoreductase FAD/NAD(P)-binding, score 3.7e-18
550537020306	HMMPfam hit to PF00970, Oxidoreductase FAD-binding region, score 0.00016
550537020307	PS00430 TonB-dependent receptor proteins signature 1.
550537020308	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
550537020309	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
550537020310	putative active site [active]
550537020311	HMMPfam hit to PF03320, GlpX, score 3.8e-243
550537020312	glycerol kinase; Provisional; Region: glpK; PRK00047
550537020313	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
550537020314	N- and C-terminal domain interface [polypeptide binding]; other site
550537020315	active site
550537020316	MgATP binding site [chemical binding]; other site
550537020317	catalytic site [active]
550537020318	metal binding site [ion binding]; metal-binding site
550537020319	glycerol binding site [chemical binding]; other site
550537020320	homotetramer interface [polypeptide binding]; other site
550537020321	homodimer interface [polypeptide binding]; other site
550537020322	FBP binding site [chemical binding]; other site
550537020323	protein IIAGlc interface [polypeptide binding]; other site
550537020324	HMMPfam hit to PF02782, Carbohydrate kinase, FGGY, score 3.6e-112
550537020325	PS00445 FGGY family of carbohydrate kinases signature 2.
550537020326	HMMPfam hit to PF00370, Carbohydrate kinase, FGGY, score 4.4e-136
550537020327	PS00933 FGGY family of carbohydrate kinases signature 1.
550537020328	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
550537020329	amphipathic channel; other site
550537020330	Asn-Pro-Ala signature motifs; other site
550537020331	HMMPfam hit to PF00230, Major intrinsic protein, score 1.2e-120
550537020332	6 probable transmembrane helices predicted for SEN3877 by TMHMM2.0 at aa 12-34, 44-66, 86-108, 145-167, 180-202 and 232-251
550537020333	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020334	PS00221 MIP family signature.
550537020335	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020336	septal ring assembly protein ZapB; Provisional; Region: PRK15422
550537020337	HMMPfam hit to PF06005, Protein of unknown function DUF904, score 3.8e-43
550537020338	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
550537020339	HMMPfam hit to PF03737, Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase, score 2.9e-77
550537020340	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
550537020341	UbiA prenyltransferase family; Region: UbiA; pfam01040
550537020342	9 probable transmembrane helices predicted for SEN3880 by TMHMM2.0 at aa 21-40, 45-64, 99-121, 125-144, 151-173, 178-200, 230-249, 253-270 and 291-308
550537020343	HMMPfam hit to PF01040, UbiA prenyltransferase, score 3.2e-47
550537020344	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020345	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
550537020346	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537020347	Walker A motif; other site
550537020348	ATP binding site [chemical binding]; other site
550537020349	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
550537020350	Walker B motif; other site
550537020351	arginine finger; other site
550537020352	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
550537020353	HMMPfam hit to PF07724, ATPase AAA-2, score 4e-56
550537020354	HMMPfam hit to PF07724, ATPase AAA-2, score 8.3e-14
550537020355	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020356	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
550537020357	active site
550537020358	HslU subunit interaction site [polypeptide binding]; other site
550537020359	HMMPfam hit to PF00227, 20S proteasome, A and B subunits, score 4.6e-36
550537020360	essential cell division protein FtsN; Provisional; Region: PRK10927
550537020361	cell division protein FtsN; Provisional; Region: PRK12757
550537020362	HMMPfam hit to PF05036, Sporulation/cell division region, bacteria, score 1.4e-19
550537020363	1 probable transmembrane helix predicted for SEN3883 by TMHMM2.0 at aa 35-57
550537020364	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537020365	DNA binding site [nucleotide binding]
550537020366	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
550537020367	domain linker motif; other site
550537020368	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
550537020369	dimerization interface [polypeptide binding]; other site
550537020370	ligand binding site [chemical binding]; other site
550537020371	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 3.4e-28
550537020372	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 9.2e-12
550537020373	PS00356 Bacterial regulatory proteins, lacI family signature.
550537020374	primosome assembly protein PriA; Validated; Region: PRK05580
550537020375	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
550537020376	ATP binding site [chemical binding]; other site
550537020377	putative Mg++ binding site [ion binding]; other site
550537020378	helicase superfamily c-terminal domain; Region: HELICc; smart00490
550537020379	ATP-binding site [chemical binding]; other site
550537020380	HMMPfam hit to PF00271, DNA/RNA helicase, C-terminal, score 5.4e-08
550537020381	HMMPfam hit to PF00270, DNA/RNA helicase, DEAD/DEAH box type, N-terminal, score 2.2e-33
550537020382	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020383	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
550537020384	HMMPfam hit to PF01197, Ribosomal protein L31, score 2e-43
550537020385	PS00190 Cytochrome c family heme-binding site signature.
550537020386	PS01143 Ribosomal protein L31 signature.
550537020387	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
550537020388	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020389	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
550537020390	HMMPfam hit to PF05935, Arylsulphotransferase, score 0
550537020391	1 probable transmembrane helix predicted for SEN3888 by TMHMM2.0 at aa 7-26
550537020392	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
550537020393	dimerization interface [polypeptide binding]; other site
550537020394	DNA binding site [nucleotide binding]
550537020395	corepressor binding sites; other site
550537020396	HMMPfam hit to PF01340, Methionine repressor MetJ, score 5.8e-89
550537020397	cystathionine gamma-synthase; Provisional; Region: PRK08045
550537020398	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
550537020399	homodimer interface [polypeptide binding]; other site
550537020400	substrate-cofactor binding pocket; other site
550537020401	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537020402	catalytic residue [active]
550537020403	HMMPfam hit to PF01053, Cys/Met metabolism, pyridoxal phosphate-dependent enzyme, score 1.8e-223
550537020404	PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site.
550537020405	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
550537020406	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
550537020407	putative catalytic residues [active]
550537020408	putative nucleotide binding site [chemical binding]; other site
550537020409	putative aspartate binding site [chemical binding]; other site
550537020410	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
550537020411	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
550537020412	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
550537020413	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 4.7e-49
550537020414	PS00324 Aspartokinase signature.
550537020415	HMMPfam hit to PF03447, Aspartate/homoserine dehydrogenase, NAD-binding, score 4.3e-43
550537020416	HMMPfam hit to PF00742, Homoserine dehydrogenase, catalytic, score 6.7e-104
550537020417	PS01042 Homoserine dehydrogenase signature.
550537020418	mechanosensitive channel MscS; Provisional; Region: PRK10334
550537020419	Conserved TM helix; Region: TM_helix; pfam05552
550537020420	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537020421	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 2.8e-72
550537020422	PS01246 Uncharacterized protein family UPF0003 signature.
550537020423	3 probable transmembrane helices predicted for SEN3892 by TMHMM2.0 at aa 23-45, 65-87 and 97-119
550537020424	HMMPfam hit to PF05552, Conserved TM helix, score 2.2e-17
550537020425	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
550537020426	9 probable transmembrane helices predicted for SEN3893 by TMHMM2.0 at aa 21-40, 60-82, 89-111, 121-143, 148-170, 175-194, 215-237, 252-274 and 295-314
550537020427	Insertion element protein; Region: Ins_element1; pfam03811
550537020428	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
550537020429	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
550537020430	active site
550537020431	metal binding site [ion binding]; metal-binding site
550537020432	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
550537020433	HMMPfam hit to PF00149, Metallophosphoesterase, score 2.8e-16
550537020434	PS00786 5'-nucleotidase signature 2.
550537020435	HMMPfam hit to PF02872, 5'-Nucleotidase, C-terminal, score 1.5e-51
550537020436	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
550537020437	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
550537020438	dimer interface [polypeptide binding]; other site
550537020439	active site
550537020440	glycine-pyridoxal phosphate binding site [chemical binding]; other site
550537020441	folate binding site [chemical binding]; other site
550537020442	HMMPfam hit to PF00464, Glycine hydroxymethyltransferase, score 5.9e-239
550537020443	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537020444	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020445	PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site.
550537020446	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
550537020447	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
550537020448	active site
550537020449	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537020450	dimer interface [polypeptide binding]; other site
550537020451	substrate binding site [chemical binding]; other site
550537020452	catalytic residues [active]
550537020453	HMMPfam hit to PF01168, Alanine racemase, N-terminal, score 4.4e-47
550537020454	HMMPfam hit to PF00842, Alanine racemase, C-terminal, score 4.2e-42
550537020455	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
550537020456	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537020457	DNA-binding site [nucleotide binding]; DNA binding site
550537020458	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537020459	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537020460	homodimer interface [polypeptide binding]; other site
550537020461	catalytic residue [active]
550537020462	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 9.2e-07
550537020463	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 6e-13
550537020464	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
550537020465	FAD binding site [chemical binding]; other site
550537020466	HMMPfam hit to PF02219, Methylenetetrahydrofolate reductase, score 1.8e-158
550537020467	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
550537020468	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
550537020469	heme binding site [chemical binding]; other site
550537020470	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
550537020471	HMMPfam hit to PF00141, Haem peroxidase, plant/fungal/bacterial, score 7.8e-85
550537020472	PS00436 Peroxidases active site signature.
550537020473	PS00435 Peroxidases proximal heme-ligand signature.
550537020474	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020475	HMMPfam hit to PF00141, Haem peroxidase, plant/fungal/bacterial, score 6.3e-106
550537020476	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
550537020477	HMMPfam hit to PF06940, Protein of unknown function DUF1287, score 1.9e-145
550537020478	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020479	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
550537020480	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
550537020481	dimer interface [polypeptide binding]; other site
550537020482	active site
550537020483	metal binding site [ion binding]; metal-binding site
550537020484	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 1.2e-87
550537020485	PS00060 Iron-containing alcohol dehydrogenases signature 2.
550537020486	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537020487	PS00913 Iron-containing alcohol dehydrogenases signature 1.
550537020488	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
550537020489	active site
550537020490	intersubunit interactions; other site
550537020491	catalytic residue [active]
550537020492	HMMPfam hit to PF00923, Transaldolase, score 2.9e-94
550537020493	PS00958 Transaldolase active site.
550537020494	PS01054 Transaldolase signature 1.
550537020495	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
550537020496	dimerization domain swap beta strand [polypeptide binding]; other site
550537020497	regulatory protein interface [polypeptide binding]; other site
550537020498	active site
550537020499	regulatory phosphorylation site [posttranslational modification]; other site
550537020500	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
550537020501	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
550537020502	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
550537020503	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
550537020504	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537020505	active site
550537020506	phosphorylation site [posttranslational modification]
550537020507	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 3.8e-11
550537020508	HMMPfam hit to PF02896, PEP-utilizing enzyme, score 1.4e-167
550537020509	PS00742 PEP-utilizing enzymes signature 2.
550537020510	HMMPfam hit to PF00391, PEP-utilising enzyme, mobile region, score 7.7e-24
550537020511	PS00370 PEP-utilizing enzymes phosphorylation site signature.
550537020512	HMMPfam hit to PF05524, Phosphotransferase system, PEP-utilising enzyme, N-terminal, score 0.00015
550537020513	HMMPfam hit to PF00381, Phosphotransferase system, phosphocarrier HPr protein, score 0.00028
550537020514	PS00369 PTS HPR component histidine phosphorylation site signature.
550537020515	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
550537020516	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
550537020517	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 8.6e-06
550537020518	8 probable transmembrane helices predicted for SEN3905 by TMHMM2.0 at aa 21-40, 60-82, 95-117, 132-154, 175-194, 214-236, 283-305 and 315-334
550537020519	5 probable transmembrane helices predicted for SEN3906 by TMHMM2.0 at aa 4-26, 39-58, 78-100, 147-169 and 179-198
550537020520	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
550537020521	active site
550537020522	P-loop; other site
550537020523	phosphorylation site [posttranslational modification]
550537020524	HMMPfam hit to PF02379, Phosphotransferase system, fructose-specific IIB subunit, score 5.1e-62
550537020525	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
550537020526	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
550537020527	dimer interface [polypeptide binding]; other site
550537020528	active site
550537020529	glycine loop; other site
550537020530	HMMPfam hit to PF02901, Pyruvate formate-lyase, PFL, score 2.7e-300
550537020531	HMMPfam hit to PF01228, Formate C-acetyltransferase glycine radical, score 2.3e-43
550537020532	PS00850 Glycine radical signature.
550537020533	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537020534	FeS/SAM binding site; other site
550537020535	pyruvate formate lyase II activase; Provisional; Region: PRK10076
550537020536	PS01087 Radical activating enzymes signature.
550537020537	HMMPfam hit to PF04055, Radical SAM, score 2.2e-15
550537020538	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
550537020539	active site
550537020540	P-loop; other site
550537020541	phosphorylation site [posttranslational modification]
550537020542	HMMPfam hit to PF02379, Phosphotransferase system, fructose-specific IIB subunit, score 2.7e-53
550537020543	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537020544	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537020545	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 5.6e-14
550537020546	PS00041 Bacterial regulatory proteins, araC family signature.
550537020547	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 3.6e-07
550537020548	hypothetical protein; Provisional; Region: PRK10649
550537020549	Sulfatase; Region: Sulfatase; pfam00884
550537020550	HMMPfam hit to PF00884, Sulphatase, score 1.6e-72
550537020551	5 probable transmembrane helices predicted for SEN3913 by TMHMM2.0 at aa 13-35, 50-67, 69-91, 118-140 and 153-170
550537020552	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
550537020553	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
550537020554	HMMPfam hit to PF00311, Phosphoenolpyruvate carboxylase, score 4.6e-227
550537020555	PS00393 Phosphoenolpyruvate carboxylase active site 2.
550537020556	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020557	PS00781 Phosphoenolpyruvate carboxylase active site 1.
550537020558	acetylornithine deacetylase; Provisional; Region: PRK05111
550537020559	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
550537020560	metal binding site [ion binding]; metal-binding site
550537020561	putative dimer interface [polypeptide binding]; other site
550537020562	HMMPfam hit to PF01546, Peptidase M20, score 7.8e-43
550537020563	HMMPfam hit to PF07687, Peptidase M20, dimerisation, score 2.3e-33
550537020564	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
550537020565	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
550537020566	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
550537020567	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
550537020568	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD - binding, score 2.1e-60
550537020569	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
550537020570	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisation region, score 1.2e-39
550537020571	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
550537020572	nucleotide binding site [chemical binding]; other site
550537020573	N-acetyl-L-glutamate binding site [chemical binding]; other site
550537020574	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 3.8e-43
550537020575	argininosuccinate lyase; Provisional; Region: PRK04833
550537020576	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
550537020577	active sites [active]
550537020578	tetramer interface [polypeptide binding]; other site
550537020579	HMMPfam hit to PF00206, Fumarate lyase, score 1e-146
550537020580	PS00163 Fumarate lyases signature.
550537020581	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
550537020582	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537020583	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
550537020584	dimerization interface [polypeptide binding]; other site
550537020585	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.4e-21
550537020586	PS00044 Bacterial regulatory proteins, lysR family signature.
550537020587	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.7e-59
550537020588	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
550537020589	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
550537020590	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
550537020591	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase dimerisation region, score 4.2e-39
550537020592	HMMPfam hit to PF07992, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, score 5.7e-44
550537020593	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region, score 1.4e-27
550537020594	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020595	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
550537020596	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537020597	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 7.7e-13
550537020598	hypothetical protein; Provisional; Region: PRK11056
550537020599	HMMPfam hit to PF07226, Protein of unknown function DUF1422, score 2.9e-78
550537020600	3 probable transmembrane helices predicted for SEN3922 by TMHMM2.0 at aa 25-47, 60-82 and 86-108
550537020601	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020602	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
550537020603	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
550537020604	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537020605	S-adenosylmethionine binding site [chemical binding]; other site
550537020606	HMMPfam hit to PF05958, (Uracil-5)-methyltransferase, score 1.5e-286
550537020607	PS01231 RNA methyltransferase trmA family signature 2.
550537020608	PS01230 RNA methyltransferase trmA family signature 1.
550537020609	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
550537020610	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
550537020611	N-terminal plug; other site
550537020612	ligand-binding site [chemical binding]; other site
550537020613	PS00430 TonB-dependent receptor proteins signature 1.
550537020614	HMMPfam hit to PF07715, TonB-dependent receptor, plug, score 1.1e-27
550537020615	HMMPfam hit to PF00593, TonB-dependent receptor, beta-barrel, score 5.4e-27
550537020616	PS01156 TonB-dependent receptor proteins signature 2.
550537020617	glutamate racemase; Provisional; Region: PRK00865
550537020618	HMMPfam hit to PF01177, Asp/Glu/hydantoin racemase, score 1.4e-90
550537020619	PS00923 Aspartate and glutamate racemases signature 1.
550537020620	PS00924 Aspartate and glutamate racemases signature 2.
550537020621	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
550537020622	FAD binding domain; Region: FAD_binding_4; pfam01565
550537020623	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
550537020624	HMMPfam hit to PF01565, FAD linked oxidase, N-terminal, score 1e-25
550537020625	HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal, score 3.8e-74
550537020626	Biotin operon repressor [Transcription]; Region: BirA; COG1654
550537020627	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
550537020628	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
550537020629	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
550537020630	HMMPfam hit to PF08279, Helix-turn-helix, type 11, score 1.6e-12
550537020631	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase, score 1e-26
550537020632	HMMPfam hit to PF02237, Biotin protein ligase, C-terminal, score 4.5e-10
550537020633	pantothenate kinase; Provisional; Region: PRK05439
550537020634	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
550537020635	ATP-binding site [chemical binding]; other site
550537020636	CoA-binding site [chemical binding]; other site
550537020637	Mg2+-binding site [ion binding]; other site
550537020638	HMMPfam hit to PF00485, Phosphoribulokinase/uridine kinase, score 4.2e-07
550537020639	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020640	elongation factor Tu; Reviewed; Region: PRK00049
550537020641	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
550537020642	G1 box; other site
550537020643	GEF interaction site [polypeptide binding]; other site
550537020644	GTP/Mg2+ binding site [chemical binding]; other site
550537020645	Switch I region; other site
550537020646	G2 box; other site
550537020647	G3 box; other site
550537020648	Switch II region; other site
550537020649	G4 box; other site
550537020650	G5 box; other site
550537020651	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
550537020652	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
550537020653	Antibiotic Binding Site [chemical binding]; other site
550537020654	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 3.3e-96
550537020655	PS00017 ATP/GTP-binding site motif A (P-loop).
550537020656	PS00301 GTP-binding elongation factors signature.
550537020657	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 2.3e-26
550537020658	HMMPfam hit to PF03143, Translation elongation factor EFTu/EF1A, C-terminal, score 1e-60
550537020659	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
550537020660	3 probable transmembrane helices predicted for SEN3931 by TMHMM2.0 at aa 19-36, 40-62 and 94-116
550537020661	HMMPfam hit to PF00584, Protein secE/sec61-gamma protein, score 3.2e-26
550537020662	PS01067 Protein secE/sec61-gamma signature.
550537020663	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
550537020664	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
550537020665	putative homodimer interface [polypeptide binding]; other site
550537020666	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
550537020667	heterodimer interface [polypeptide binding]; other site
550537020668	homodimer interface [polypeptide binding]; other site
550537020669	HMMPfam hit to PF02357, Transcription antitermination protein, NusG, N-terminal, score 1.6e-56
550537020670	HMMPfam hit to PF00467, KOW, score 1.6e-11
550537020671	PS01014 Transcription termination factor nusG signature.
550537020672	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
550537020673	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
550537020674	23S rRNA interface [nucleotide binding]; other site
550537020675	L7/L12 interface [polypeptide binding]; other site
550537020676	putative thiostrepton binding site; other site
550537020677	L25 interface [polypeptide binding]; other site
550537020678	HMMPfam hit to PF03946, Ribosomal protein L11, score 2.1e-38
550537020679	HMMPfam hit to PF00298, Ribosomal protein L11, score 6.8e-39
550537020680	PS00359 Ribosomal protein L11 signature.
550537020681	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
550537020682	mRNA/rRNA interface [nucleotide binding]; other site
550537020683	HMMPfam hit to PF00687, Ribosomal protein L1, score 3.6e-136
550537020684	PS01199 Ribosomal protein L1 signature.
550537020685	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
550537020686	23S rRNA interface [nucleotide binding]; other site
550537020687	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
550537020688	HMMPfam hit to PF00466, Ribosomal protein L10, score 1.5e-36
550537020689	PS01109 Ribosomal protein L10 signature.
550537020690	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
550537020691	core dimer interface [polypeptide binding]; other site
550537020692	peripheral dimer interface [polypeptide binding]; other site
550537020693	L10 interface [polypeptide binding]; other site
550537020694	L11 interface [polypeptide binding]; other site
550537020695	putative EF-Tu interaction site [polypeptide binding]; other site
550537020696	putative EF-G interaction site [polypeptide binding]; other site
550537020697	HMMPfam hit to PF00542, Ribosomal protein L7/L12, C-terminal, score 1.6e-37
550537020698	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
550537020699	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
550537020700	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
550537020701	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
550537020702	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
550537020703	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
550537020704	RPB3 interaction site [polypeptide binding]; other site
550537020705	RPB1 interaction site [polypeptide binding]; other site
550537020706	RPB11 interaction site [polypeptide binding]; other site
550537020707	RPB10 interaction site [polypeptide binding]; other site
550537020708	HMMPfam hit to PF04563, RNA polymerase, beta subunit, protrusion, score 5.4e-36
550537020709	HMMPfam hit to PF04561, RNA polymerase Rpb2, domain 2, score 4.3e-06
550537020710	HMMPfam hit to PF04565, RNA polymerase Rpb2, domain 3, score 1.8e-43
550537020711	HMMPfam hit to PF00562, RNA polymerase Rpb2, domain 6, score 6e-187
550537020712	PS01166 RNA polymerases beta chain signature.
550537020713	HMMPfam hit to PF04560, RNA polymerase Rpb2, domain 7, score 4.2e-52
550537020714	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
550537020715	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
550537020716	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
550537020717	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
550537020718	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
550537020719	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
550537020720	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
550537020721	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
550537020722	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
550537020723	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
550537020724	DNA binding site [nucleotide binding]
550537020725	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
550537020726	HMMPfam hit to PF04997, RNA polymerase Rpb1, domain 1, score 1.6e-168
550537020727	HMMPfam hit to PF00623, RNA polymerase, alpha subunit, score 2e-83
550537020728	HMMPfam hit to PF04983, RNA polymerase Rpb1, domain 3, score 1.8e-54
550537020729	HMMPfam hit to PF05000, RNA polymerase Rpb1, domain 4, score 7.2e-30
550537020730	HMMPfam hit to PF04998, RNA polymerase Rpb1, domain 5, score 2.2e-110
550537020731	Low G+C region
550537020732	3 probable transmembrane helices predicted for SEN3939 by TMHMM2.0 at aa 20-42, 52-74 and 86-105
550537020733	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
550537020734	HMMPfam hit to PF03326, Herpesvirus transcription activation factor, score 0.00093
550537020735	type III secretion system protein; Provisional; Region: PRK15384
550537020736	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
550537020737	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
550537020738	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537020739	FeS/SAM binding site; other site
550537020740	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
550537020741	HMMPfam hit to PF06968, Biotin and thiamin synthesis associated, score 9.9e-40
550537020742	HMMPfam hit to PF04055, Radical SAM, score 2.9e-09
550537020743	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
550537020744	ThiS interaction site; other site
550537020745	putative active site [active]
550537020746	tetramer interface [polypeptide binding]; other site
550537020747	HMMPfam hit to PF05690, Thiazole biosynthesis, score 2.8e-176
550537020748	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
550537020749	thiS-thiF/thiG interaction site; other site
550537020750	HMMPfam hit to PF02597, ThiamineS, score 2.7e-17
550537020751	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
550537020752	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
550537020753	ATP binding site [chemical binding]; other site
550537020754	substrate interface [chemical binding]; other site
550537020755	HMMPfam hit to PF05237, MoeZ/MoeB, score 1.1e-40
550537020756	HMMPfam hit to PF00899, UBA/THIF-type NAD/FAD binding fold, score 3.6e-62
550537020757	1 probable transmembrane helix predicted for SEN3948 by TMHMM2.0 at aa 26-48
550537020758	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
550537020759	thiamine phosphate binding site [chemical binding]; other site
550537020760	active site
550537020761	pyrophosphate binding site [ion binding]; other site
550537020762	HMMPfam hit to PF02581, Thiamine monophosphate synthase, score 1.6e-84
550537020763	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
550537020764	ThiC-associated domain; Region: ThiC-associated; pfam13667
550537020765	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
550537020766	HMMPfam hit to PF01964, Thiamine biosynthesis protein ThiC, score 0
550537020767	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020768	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
550537020769	HMMPfam hit to PF04353, Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ, score 4.8e-103
550537020770	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
550537020771	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
550537020772	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
550537020773	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
550537020774	putative NADH binding site [chemical binding]; other site
550537020775	putative active site [active]
550537020776	nudix motif; other site
550537020777	putative metal binding site [ion binding]; other site
550537020778	HMMPfam hit to PF09296, NADH pyrophosphatase-like, N-terminal, score 2.2e-12
550537020779	HMMPfam hit to PF09297, Zinc ribbon, NADH pyrophosphatase, score 1.5e-14
550537020780	HMMPfam hit to PF00293, NUDIX hydrolase, core, score 1.3e-30
550537020781	PS00893 mutT domain signature.
550537020782	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
550537020783	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
550537020784	substrate binding site [chemical binding]; other site
550537020785	active site
550537020786	HMMPfam hit to PF01208, Uroporphyrinogen decarboxylase (URO-D), score 9.5e-218
550537020787	PS00906 Uroporphyrinogen decarboxylase signature 1.
550537020788	PS00907 Uroporphyrinogen decarboxylase signature 2.
550537020789	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
550537020790	Active_site [active]
550537020791	HMMPfam hit to PF04493, Endonuclease V, score 1.3e-107
550537020792	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
550537020793	HMMPfam hit to PF04222, Protein of unknown function DUF416, score 1.6e-160
550537020794	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
550537020795	IHF dimer interface [polypeptide binding]; other site
550537020796	IHF - DNA interface [nucleotide binding]; other site
550537020797	HMMPfam hit to PF00216, Histone-like bacterial DNA-binding protein, score 7e-51
550537020798	PS00045 Bacterial histone-like DNA-binding proteins signature.
550537020799	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
550537020800	HMMPfam hit to PF07356, Protein of unknown function DUF1481, score 2.8e-178
550537020801	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020802	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
550537020803	dimer interface [polypeptide binding]; other site
550537020804	1 probable transmembrane helix predicted for SEN3958 by TMHMM2.0 at aa 7-29
550537020805	sensor protein ZraS; Provisional; Region: PRK10364
550537020806	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537020807	dimer interface [polypeptide binding]; other site
550537020808	phosphorylation site [posttranslational modification]
550537020809	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537020810	ATP binding site [chemical binding]; other site
550537020811	Mg2+ binding site [ion binding]; other site
550537020812	G-X-G motif; other site
550537020813	2 probable transmembrane helices predicted for SEN3959 by TMHMM2.0 at aa 13-35 and 204-223
550537020814	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 3.9e-16
550537020815	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2.8e-39
550537020816	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
550537020817	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537020818	active site
550537020819	phosphorylation site [posttranslational modification]
550537020820	intermolecular recognition site; other site
550537020821	dimerization interface [polypeptide binding]; other site
550537020822	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537020823	Walker A motif; other site
550537020824	ATP binding site [chemical binding]; other site
550537020825	Walker B motif; other site
550537020826	arginine finger; other site
550537020827	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
550537020828	HMMPfam hit to PF00072, Response regulator receiver, score 6.9e-49
550537020829	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 1.5e-160
550537020830	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537020831	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537020832	PS00688 Sigma-54 interaction domain C-terminal part signature.
550537020833	HMMPfam hit to PF02954, Helix-turn-helix, Fis-type, score 8.8e-16
550537020834	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
550537020835	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
550537020836	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
550537020837	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
550537020838	HMMPfam hit to PF02843, Phosphoribosylglycinamide synthetase, score 7.8e-51
550537020839	PS00184 Phosphoribosylglycinamide synthetase signature.
550537020840	HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, score 2.3e-138
550537020841	HMMPfam hit to PF02844, Phosphoribosylglycinamide synthetase, score 7.7e-65
550537020842	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
550537020843	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
550537020844	purine monophosphate binding site [chemical binding]; other site
550537020845	dimer interface [polypeptide binding]; other site
550537020846	putative catalytic residues [active]
550537020847	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
550537020848	HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme, formylation region, score 9.5e-224
550537020849	HMMPfam hit to PF02142, MGS-like, score 1.5e-62
550537020850	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
550537020851	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537020852	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
550537020853	Coenzyme A binding pocket [chemical binding]; other site
550537020854	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 5.1e-19
550537020855	homoserine O-succinyltransferase; Provisional; Region: PRK05368
550537020856	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
550537020857	proposed active site lysine [active]
550537020858	conserved cys residue [active]
550537020859	HMMPfam hit to PF04204, Homoserine O-succinyltransferase, score 1.4e-204
550537020860	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
550537020861	malate synthase A; Region: malate_syn_A; TIGR01344
550537020862	active site
550537020863	HMMPfam hit to PF01274, Malate synthase, score 0
550537020864	PS00510 Malate synthase signature.
550537020865	isocitrate lyase; Provisional; Region: PRK15063
550537020866	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
550537020867	tetramer interface [polypeptide binding]; other site
550537020868	active site
550537020869	Mg2+/Mn2+ binding site [ion binding]; other site
550537020870	HMMPfam hit to PF00463, Isocitrate lyase and phosphorylmutase, score 1.3e-288
550537020871	PS00161 Isocitrate lyase signature.
550537020872	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
550537020873	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
550537020874	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
550537020875	HMMPfam hit to PF06315, Isocitrate dehydrogenase kinasephosphatase, score 0
550537020876	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537020877	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
550537020878	HMMPfam hit to PF06171, Protein of unknown function DUF984, score 9.9e-71
550537020879	transcriptional repressor IclR; Provisional; Region: PRK11569
550537020880	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
550537020881	Bacterial transcriptional regulator; Region: IclR; pfam01614
550537020882	HMMPfam hit to PF01614, Transcriptional regulator IclR, C-terminal, score 7.6e-54
550537020883	PS01051 Bacterial regulatory proteins, iclR family signature.
550537020884	HMMPfam hit to PF09339, Transcriptional regulator IclR, N-terminal, score 6.1e-33
550537020885	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
550537020886	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
550537020887	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
550537020888	substrate binding pocket [chemical binding]; other site
550537020889	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
550537020890	B12 binding site [chemical binding]; other site
550537020891	cobalt ligand [ion binding]; other site
550537020892	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
550537020893	HMMPfam hit to PF02574, Homocysteine S-methyltransferase, score 4.5e-167
550537020894	HMMPfam hit to PF00809, Dihydropteroate synthase, DHPS, score 1.5e-80
550537020895	HMMPfam hit to PF02607, Methionine synthase, cobalamin (vitamin B12)-binding module, cap, score 9.1e-46
550537020896	HMMPfam hit to PF02310, Cobalamin (vitamin B12)-binding, score 2.4e-28
550537020897	HMMPfam hit to PF02965, Vitamin B12 dependent methionine synthase, activation region, score 1.8e-80
550537020898	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
550537020899	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
550537020900	HMMPfam hit to PF02690, Na+/Pi-cotransporter, score 1e-51
550537020901	7 probable transmembrane helices predicted for SEN3972 by TMHMM2.0 at aa 42-64, 74-96, 108-130, 150-172, 177-199, 214-236 and 249-271
550537020903	HMMPfam hit to PF03575, Peptidase S51, dipeptidase E, score 4.1e-79
550537020904	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
550537020905	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
550537020906	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
550537020907	RNA binding surface [nucleotide binding]; other site
550537020908	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
550537020909	probable active site [active]
550537020910	HMMPfam hit to PF01479, RNA-binding S4, score 8.5e-13
550537020911	HMMPfam hit to PF00849, Pseudouridine synthase, score 4.2e-27
550537020912	PS01149 Rsu family of pseudouridine synthase signature.
550537020913	hypothetical protein; Provisional; Region: PRK10515
550537020914	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
550537020915	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
550537020916	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537020917	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 1.3e-34
550537020918	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 2.3e-17
550537020919	PS00894 Bacterial regulatory proteins, deoR family signature.
550537020920	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
550537020921	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537020922	HMMPfam hit to PF08282, HAD superfamily hydrolase-like, type 3, score 2.2e-52
550537020923	PS01229 Hypothetical cof family signature 2.
550537020924	PS01228 Hypothetical cof family signature 1.
550537020925	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
550537020926	active site
550537020927	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
550537020928	phosphate binding site [ion binding]; other site
550537020929	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
550537020930	8 probable transmembrane helices predicted for SEN3981 by TMHMM2.0 at aa 222-244, 291-313, 325-347, 377-399, 406-428, 438-460, 467-486 and 506-528
550537020931	Low G+C region
550537020932	Carries a frameshift mutation following codon 54. Note the database hit is weak and partial
550537020933	PS00101 Hexapeptide-repeat containing-transferases signature.
550537020934	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 9.1
550537020935	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 8.4
550537020936	HMMPfam hit to PF00132, Bacterial transferase hexapeptide repeat, score 30
550537020937	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537020938	Mor transcription activator family; Region: Mor; pfam08765
550537020939	HMMPfam hit to PF08765, Mor transcription activator, score 7.7e-56
550537020940	aspartate kinase III; Validated; Region: PRK09084
550537020941	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
550537020942	nucleotide binding site [chemical binding]; other site
550537020943	substrate binding site [chemical binding]; other site
550537020944	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
550537020945	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
550537020946	dimer interface [polypeptide binding]; other site
550537020947	HMMPfam hit to PF01842, Amino acid-binding ACT, score 5.4e-06
550537020948	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 2.3e-62
550537020949	PS00324 Aspartokinase signature.
550537020950	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
550537020951	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
550537020952	active site
550537020953	dimer interface [polypeptide binding]; other site
550537020954	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
550537020955	dimer interface [polypeptide binding]; other site
550537020956	active site
550537020957	HMMPfam hit to PF00342, Phosphoglucose isomerase (PGI), score 0
550537020958	PS00765 Phosphoglucose isomerase signature 1.
550537020959	PS00174 Phosphoglucose isomerase signature 2.
550537020960	1 probable transmembrane helix predicted for SEN3988 by TMHMM2.0 at aa 5-27
550537020961	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
550537020962	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020963	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
550537020964	HMMPfam hit to PF06251, Protein of unknown function DUF1017, score 6.8e-151
550537020965	1 probable transmembrane helix predicted for SEN3991 by TMHMM2.0 at aa 5-27
550537020966	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
550537020967	HMMPfam hit to PF06082, Protein of unknown function DUF940, bacterial membrane lipoprotein , score 0
550537020968	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020969	Predicted membrane protein [Function unknown]; Region: COG3223
550537020970	HMMPfam hit to PF06146, Phosphate-starvation-inducible E, score 2.1e-76
550537020971	4 probable transmembrane helices predicted for SEN3993 by TMHMM2.0 at aa 13-35, 55-77, 84-103 and 113-130
550537020972	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
550537020973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537020974	dimer interface [polypeptide binding]; other site
550537020975	conserved gate region; other site
550537020976	putative PBP binding loops; other site
550537020977	ABC-ATPase subunit interface; other site
550537020978	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 2.3e-17
550537020979	6 probable transmembrane helices predicted for SEN3994 by TMHMM2.0 at aa 13-35, 89-111, 124-143, 153-175, 205-227 and 258-280
550537020980	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537020981	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
550537020982	dimer interface [polypeptide binding]; other site
550537020983	conserved gate region; other site
550537020984	putative PBP binding loops; other site
550537020985	ABC-ATPase subunit interface; other site
550537020986	HMMPfam hit to PF00528, Binding-protein-dependent transport systems inner membrane component, score 5e-11
550537020987	8 probable transmembrane helices predicted for SEN3995 by TMHMM2.0 at aa 17-36, 40-57, 70-92, 284-306, 319-341, 370-392, 413-435 and 484-506
550537020988	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
550537020989	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537020990	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
550537020991	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
550537020992	HMMPfam hit to PF01547, Bacterial extracellular solute-binding protein, family 1, score 4.1e-40
550537020993	PS01037 Bacterial extracellular solute-binding proteins, family 1 signature.
550537020994	1 probable transmembrane helix predicted for SEN3997 by TMHMM2.0 at aa 7-29
550537020995	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
550537020996	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
550537020997	Walker A/P-loop; other site
550537020998	ATP binding site [chemical binding]; other site
550537020999	Q-loop/lid; other site
550537021000	ABC transporter signature motif; other site
550537021001	Walker B; other site
550537021002	D-loop; other site
550537021003	H-loop/switch region; other site
550537021004	TOBE domain; Region: TOBE_2; pfam08402
550537021005	HMMPfam hit to PF00005, ABC transporter related, score 7.1e-59
550537021006	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021007	PS00211 ABC transporters family signature.
550537021008	HMMPfam hit to PF08402, Transport-associated OB, type 2, score 1.9e-15
550537021009	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
550537021010	trimer interface; other site
550537021011	sugar binding site [chemical binding]; other site
550537021012	HMMPfam hit to PF02264, Porin, LamB type, score 5.6e-277
550537021013	maltose regulon periplasmic protein; Provisional; Region: PRK10564
550537021014	1 probable transmembrane helix predicted for SEN4001 by TMHMM2.0 at aa 7-26
550537021015	HMMPfam hit to PF07148, Maltose operon periplasmic, score 4.6e-176
550537021016	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
550537021017	HMMPfam hit to PF04345, Chorismate lyase, score 8.1e-26
550537021018	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
550537021019	UbiA prenyltransferase family; Region: UbiA; pfam01040
550537021020	7 probable transmembrane helices predicted for SEN4003 by TMHMM2.0 at aa 23-40, 45-67, 99-132, 160-182, 203-225, 229-251 and 272-289
550537021021	HMMPfam hit to PF01040, UbiA prenyltransferase, score 1.5e-84
550537021022	PS00943 UbiA prenyltransferase family signature.
550537021023	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
550537021024	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
550537021025	putative acyl-acceptor binding pocket; other site
550537021026	HMMPfam hit to PF01553, Phospholipid/glycerol acyltransferase, score 1.3e-44
550537021027	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
550537021028	HMMPfam hit to PF01219, Prokaryotic diacylglycerol kinase, score 6e-57
550537021029	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021030	2 probable transmembrane helices predicted for SEN4005 by TMHMM2.0 at aa 57-79 and 99-121
550537021031	PS01069 Prokaryotic diacylglycerol kinase signature.
550537021032	LexA repressor; Validated; Region: PRK00215
550537021033	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
550537021034	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
550537021035	Catalytic site [active]
550537021036	HMMPfam hit to PF01726, LexA DNA-binding region, score 2.3e-47
550537021037	HMMPfam hit to PF00717, Peptidase S24, S26A and S26B, C-terminal, score 1.5e-21
550537021038	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
550537021039	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
550537021040	12 probable transmembrane helices predicted for SEN4007 by TMHMM2.0 at aa 11-33, 43-65, 89-111, 131-153, 160-182, 187-209, 241-263, 267-289, 321-343, 353-375, 388-405 and 409-428
550537021041	HMMPfam hit to PF01554, Multi antimicrobial extrusion protein MatE, score 4.3e-39
550537021042	HMMPfam hit to PF01554, Multi antimicrobial extrusion protein MatE, score 0.0013
550537021043	hypothetical protein; Provisional; Region: PRK10428
550537021044	HMMPfam hit to PF05532, CsbD-like, score 1.1e-24
550537021045	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
550537021046	metal binding site 2 [ion binding]; metal-binding site
550537021047	putative DNA binding helix; other site
550537021048	metal binding site 1 [ion binding]; metal-binding site
550537021049	dimer interface [polypeptide binding]; other site
550537021050	structural Zn2+ binding site [ion binding]; other site
550537021051	HMMPfam hit to PF01475, Ferric-uptake regulator, score 2.6e-05
550537021052	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
550537021053	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
550537021054	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
550537021055	FMN binding site [chemical binding]; other site
550537021056	active site
550537021057	catalytic residues [active]
550537021058	substrate binding site [chemical binding]; other site
550537021059	HMMPfam hit to PF01207, Dihydrouridine synthase, DuS, score 3.2e-143
550537021060	PS01136 Uncharacterized protein family UPF0034 signature.
550537021061	phage shock protein G; Reviewed; Region: pspG; PRK09459
550537021062	2 probable transmembrane helices predicted for SEN4013 by TMHMM2.0 at aa 5-27 and 32-49
550537021063	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
550537021064	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
550537021065	NADP binding site [chemical binding]; other site
550537021066	dimer interface [polypeptide binding]; other site
550537021067	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 2.2e-36
550537021068	PS01162 Quinone oxidoreductase / zeta-crystallin signature.
550537021069	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021070	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 8.5e-21
550537021071	replicative DNA helicase; Provisional; Region: PRK08006
550537021072	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
550537021073	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
550537021074	Walker A motif; other site
550537021075	ATP binding site [chemical binding]; other site
550537021076	Walker B motif; other site
550537021077	DNA binding loops [nucleotide binding]
550537021078	HMMPfam hit to PF00772, DNA helicase, DnaB-like, N-terminal, score 5.8e-58
550537021079	HMMPfam hit to PF03796, DNA helicase, DnaB-like, C-terminal, score 2e-136
550537021080	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021081	alanine racemase; Reviewed; Region: alr; PRK00053
550537021082	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
550537021083	active site
550537021084	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
550537021085	substrate binding site [chemical binding]; other site
550537021086	catalytic residues [active]
550537021087	dimer interface [polypeptide binding]; other site
550537021088	HMMPfam hit to PF01168, Alanine racemase, N-terminal, score 5.1e-97
550537021089	PS00395 Alanine racemase pyridoxal-phosphate attachment site.
550537021090	HMMPfam hit to PF00842, Alanine racemase, C-terminal, score 2e-68
550537021091	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
550537021092	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
550537021093	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537021094	homodimer interface [polypeptide binding]; other site
550537021095	catalytic residue [active]
550537021096	HMMPfam hit to PF00155, Aminotransferase, class I and II, score 5.3e-128
550537021097	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
550537021098	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
550537021099	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537021100	active site
550537021101	motif I; other site
550537021102	motif II; other site
550537021103	HMMPfam hit to PF03767, Acid phosphatase (Class B), score 3.1e-61
550537021104	Uncharacterized conserved protein [Function unknown]; Region: COG0432
550537021105	HMMPfam hit to PF01894, Protein of unknown function UPF0047, score 1e-53
550537021106	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
550537021107	HMMPfam hit to PF04237, Protein of unknown function DUF419, score 1.4e-53
550537021108	1 probable transmembrane helix predicted for SEN4022 by TMHMM2.0 at aa 7-29
550537021109	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021110	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
550537021111	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
550537021112	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
550537021113	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
550537021114	HMMPfam hit to PF00005, ABC transporter related, score 6.3e-46
550537021115	PS00211 ABC transporters family signature.
550537021116	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021117	PS00211 ABC transporters family signature.
550537021118	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021119	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
550537021120	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
550537021121	dimer interface [polypeptide binding]; other site
550537021122	ssDNA binding site [nucleotide binding]; other site
550537021123	tetramer (dimer of dimers) interface [polypeptide binding]; other site
550537021124	HMMPfam hit to PF00436, Primosome PriB/single-strand DNA-binding, score 1.4e-35
550537021125	PS00735 Single-strand binding protein family signature 1.
550537021126	PS00736 Single-strand binding protein family signature 2.
550537021127	Salmonella Pathogenicity Island 4: SPI-4
550537021128	hypothetical protein; Validated; Region: PRK09039
550537021129	1 probable transmembrane helix predicted for SEN4026 by TMHMM2.0 at aa 15-37
550537021130	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
550537021131	4 probable transmembrane helices predicted for SEN4027 by TMHMM2.0 at aa 7-26, 41-63, 131-153 and 186-208
550537021132	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
550537021133	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.7e-35
550537021134	HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.4e-42
550537021135	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
550537021136	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
550537021137	HlyD family secretion protein; Region: HlyD_3; pfam13437
550537021138	1 probable transmembrane helix predicted for SEN4029 by TMHMM2.0 at aa 12-34
550537021139	HMMPfam hit to PF00364, Biotin/lipoyl attachment, score 0.00012
550537021140	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021141	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021142	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021143	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021144	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021145	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537021146	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021147	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021148	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021149	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021150	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537021151	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021152	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021153	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537021154	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021155	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021156	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021157	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021158	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537021159	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021160	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021161	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537021162	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021163	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021164	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021165	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021166	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
550537021167	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021168	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021169	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021170	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021171	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021172	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021173	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
550537021174	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021175	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
550537021176	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021177	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021178	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
550537021179	HMMPfam hit to PF07495, Two component regulator three Y, score 0.00094
550537021180	PS00307 Legume lectins beta-chain signature.
550537021181	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 5.4
550537021182	HMMPfam hit to PF07495, Two component regulator three Y, score 0.011
550537021183	HMMPfam hit to PF07495, Two component regulator three Y, score 0.014
550537021184	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 1
550537021185	HMMPfam hit to PF07495, Two component regulator three Y, score 0.0053
550537021186	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 1.1
550537021187	HMMPfam hit to PF07495, Two component regulator three Y, score 0.0006
550537021188	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 3.8
550537021189	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 1
550537021190	HMMPfam hit to PF07495, Two component regulator three Y, score 0.00076
550537021191	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 2.3
550537021192	HMMPfam hit to PF07495, Two component regulator three Y, score 0.00076
550537021193	HMMPfam hit to PF07495, Two component regulator three Y, score 0.014
550537021194	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 1
550537021195	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 1.4
550537021196	PS00213 Lipocalin signature.
550537021197	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 4.4
550537021198	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 3.9
550537021199	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 8.4
550537021200	HMMPfam hit to PF07495, Two component regulator three Y, score 5.4e-05
550537021201	HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 52
550537021202	PS01228 Hypothetical cof family signature 1.
550537021203	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021204	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
550537021205	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
550537021206	Walker A/P-loop; other site
550537021207	ATP binding site [chemical binding]; other site
550537021208	Q-loop/lid; other site
550537021209	ABC transporter signature motif; other site
550537021210	Walker B; other site
550537021211	D-loop; other site
550537021212	H-loop/switch region; other site
550537021213	5 probable transmembrane helices predicted for SEN4032 by TMHMM2.0 at aa 157-179, 189-208, 262-284, 288-310 and 376-398
550537021214	PS00501 Signal peptidases I serine active site.
550537021215	HMMPfam hit to PF00005, ABC transporter related, score 2.4e-42
550537021216	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021217	2 probable transmembrane helices predicted for SEN4033 by TMHMM2.0 at aa 10-29 and 36-58
550537021218	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021219	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
550537021220	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
550537021221	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
550537021222	2 probable transmembrane helices predicted for SEN4034 by TMHMM2.0 at aa 10-32 and 239-261
550537021223	HMMPfam hit to PF00563, EAL, score 8e-114
550537021224	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
550537021225	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537021226	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 6e-13
550537021227	PS00041 Bacterial regulatory proteins, araC family signature.
550537021228	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 8.7e-11
550537021229	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
550537021230	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
550537021231	DNA binding residues [nucleotide binding]
550537021232	dimer interface [polypeptide binding]; other site
550537021233	[2Fe-2S] cluster binding site [ion binding]; other site
550537021234	HMMPfam hit to PF00376, Bacterial regulatory protein, MerR, score 2e-12
550537021235	PS00552 Bacterial regulatory proteins, merR family signature.
550537021236	HMMPfam hit to PF09278, Transcription regulator MerR, DNA binding, score 3.2e-17
550537021237	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
550537021238	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
550537021239	putative C-terminal domain interface [polypeptide binding]; other site
550537021240	putative GSH binding site (G-site) [chemical binding]; other site
550537021241	putative dimer interface [polypeptide binding]; other site
550537021242	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
550537021243	putative N-terminal domain interface [polypeptide binding]; other site
550537021244	putative dimer interface [polypeptide binding]; other site
550537021245	putative substrate binding pocket (H-site) [chemical binding]; other site
550537021246	HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal, score 8.7e-14
550537021247	HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal, score 6.6e-08
550537021248	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
550537021249	HMMPfam hit to PF00860, Xanthine/uracil/vitamin C permease, score 7.9e-113
550537021250	12 probable transmembrane helices predicted for SEN4038 by TMHMM2.0 at aa 29-51, 56-78, 85-107, 112-134, 146-165, 175-197, 202-224, 244-266, 329-351, 356-378, 391-413 and 428-447
550537021251	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021252	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021253	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
550537021254	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
550537021255	9 probable transmembrane helices predicted for SEN4039 by TMHMM2.0 at aa 4-26, 86-108, 113-135, 181-203, 233-255, 276-298, 313-335, 361-383 and 398-420
550537021256	HMMPfam hit to PF00999, Sodium/hydrogen exchanger, score 3.7e-83
550537021257	Transcriptional regulator [Transcription]; Region: LysR; COG0583
550537021258	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537021259	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
550537021260	putative dimerization interface [polypeptide binding]; other site
550537021261	HMMPfam hit to PF03466, LysR, substrate-binding, score 1.1e-43
550537021262	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 1.2e-23
550537021263	PS00044 Bacterial regulatory proteins, lysR family signature.
550537021264	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
550537021265	HMMPfam hit to PF03788, LrgA, score 8.8e-32
550537021266	4 probable transmembrane helices predicted for SEN4041 by TMHMM2.0 at aa 20-42, 47-66, 73-95 and 100-122
550537021267	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
550537021268	6 probable transmembrane helices predicted for SEN4042 by TMHMM2.0 at aa 4-21, 33-54, 64-86, 93-115, 149-171 and 203-225
550537021269	HMMPfam hit to PF04172, LrgB-like protein, score 4.7e-106
550537021270	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
550537021271	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
550537021272	Na binding site [ion binding]; other site
550537021273	13 probable transmembrane helices predicted for SEN4043 by TMHMM2.0 at aa 33-55, 76-98, 103-125, 146-168, 183-205, 212-234, 261-283, 303-325, 362-384, 404-423, 428-450, 462-484 and 494-516
550537021274	PS00457 Sodium:solute symporter family signature 2.
550537021275	HMMPfam hit to PF00474, Na+/solute symporter, score 2.7e-198
550537021276	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021277	PS00456 Sodium:solute symporter family signature 1.
550537021278	Predicted membrane protein [Function unknown]; Region: COG3162
550537021279	HMMPfam hit to PF04341, Protein of unknown function DUF485, score 1.3e-60
550537021280	2 probable transmembrane helices predicted for SEN4044 by TMHMM2.0 at aa 25-47 and 62-84
550537021281	acetyl-CoA synthetase; Provisional; Region: PRK00174
550537021282	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
550537021283	active site
550537021284	CoA binding site [chemical binding]; other site
550537021285	acyl-activating enzyme (AAE) consensus motif; other site
550537021286	AMP binding site [chemical binding]; other site
550537021287	acetate binding site [chemical binding]; other site
550537021288	HMMPfam hit to PF00501, AMP-dependent synthetase and ligase, score 3.3e-141
550537021289	PS00455  AMP-binding domain signature.
550537021290	PS00018 EF-hand calcium-binding domain.
550537021291	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
550537021292	HMMPfam hit to PF02335, Cytochrome c552, score 0
550537021293	PS00190 Cytochrome c family heme-binding site signature.
550537021294	PS00190 Cytochrome c family heme-binding site signature.
550537021295	PS00190 Cytochrome c family heme-binding site signature.
550537021296	PS00190 Cytochrome c family heme-binding site signature.
550537021297	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
550537021298	PS00190 Cytochrome c family heme-binding site signature.
550537021299	PS00190 Cytochrome c family heme-binding site signature.
550537021300	PS00190 Cytochrome c family heme-binding site signature.
550537021301	PS00190 Cytochrome c family heme-binding site signature.
550537021302	PS00190 Cytochrome c family heme-binding site signature.
550537021303	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
550537021304	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0024
550537021305	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 9.1e-06
550537021306	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537021307	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
550537021308	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
550537021309	HMMPfam hit to PF03916, Polysulphide reductase, NrfD, score 3.1e-148
550537021310	8 probable transmembrane helices predicted for SEN4050 by TMHMM2.0 at aa 15-37, 57-76, 91-113, 151-170, 180-202, 223-241, 256-278 and 290-312
550537021311	heme lyase subunit NrfE; Provisional; Region: PRK10369
550537021312	HMMPfam hit to PF01578, Cytochrome c assembly protein, score 2e-67
550537021313	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
550537021314	2 probable transmembrane helices predicted for SEN4052 by TMHMM2.0 at aa 30-49 and 130-149
550537021315	HMMPfam hit to PF03918, Cytochrome C biogenesis protein, score 3e-42
550537021316	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
550537021317	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
550537021318	binding surface
550537021319	TPR motif; other site
550537021320	1 probable transmembrane helix predicted for SEN4053 by TMHMM2.0 at aa 20-37
550537021321	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021322	HMMPfam hit to PF00515, Tetratricopeptide TPR-1, score 8.6e-05
550537021323	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
550537021324	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
550537021325	8 probable transmembrane helices predicted for SEN4054 by TMHMM2.0 at aa 7-29, 49-71, 84-106, 163-185, 206-228, 233-255, 354-376 and 391-409
550537021326	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter, score 2.4e-224
550537021327	PS00713 Sodium:dicarboxylate symporter family signature 1.
550537021328	PS00714 Sodium:dicarboxylate symporter family signature 2.
550537021329	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
550537021330	Sel1-like repeats; Region: SEL1; smart00671
550537021331	HMMPfam hit to PF08238, Sel1-like, score 0.00082
550537021332	HMMPfam hit to PF08238, Sel1-like, score 0.0009
550537021333	HMMPfam hit to PF08238, Sel1-like, score 0.44
550537021334	HMMPfam hit to PF08238, Sel1-like, score 0.00083
550537021335	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
550537021336	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
550537021337	[4Fe-4S] binding site [ion binding]; other site
550537021338	molybdopterin cofactor binding site; other site
550537021339	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
550537021340	molybdopterin cofactor binding site; other site
550537021341	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 1.6e-34
550537021342	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 5.6e-183
550537021343	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 7e-22
550537021344	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
550537021345	2 probable transmembrane helices predicted for SEN4057 by TMHMM2.0 at aa 4-22 and 279-301
550537021346	HMMPfam hit to PF05118, Aspartyl/Asparaginyl beta-hydroxylase, score 6e-93
550537021347	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537021348	Coenzyme A binding pocket [chemical binding]; other site
550537021349	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 4.9e-18
550537021350	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
550537021351	dimer interface [polypeptide binding]; other site
550537021352	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
550537021353	HMMPfam hit to PF00903, Glyoxalase/bleomycin resistance protein/dioxygenase, score 0.0004
550537021354	hypothetical protein; Provisional; Region: PRK10220
550537021355	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
550537021356	PhnA protein; Region: PhnA; pfam03831
550537021357	HMMPfam hit to PF03831, PhnA protein, C-terminal, score 7.7e-37
550537021358	HMMPfam hit to PF08274, PhnA protein, N-terminal, score 2.6e-17
550537021359	proline/glycine betaine transporter; Provisional; Region: PRK10642
550537021360	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537021361	putative substrate translocation pore; other site
550537021362	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
550537021363	HMMPfam hit to PF00083, General substrate transporter, score 2.9e-96
550537021364	12 probable transmembrane helices predicted for SEN4061 by TMHMM2.0 at aa 30-52, 67-89, 98-120, 124-146, 167-189, 199-221, 260-282, 297-319, 326-346, 351-373, 386-408 and 418-437
550537021365	PS00216 Sugar transport proteins signature 1.
550537021366	HMMPfam hit to PF08946, Osmosensory transporter coiled coil, score 3e-23
550537021367	sensor protein BasS/PmrB; Provisional; Region: PRK10755
550537021368	HAMP domain; Region: HAMP; pfam00672
550537021369	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537021370	dimer interface [polypeptide binding]; other site
550537021371	phosphorylation site [posttranslational modification]
550537021372	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537021373	ATP binding site [chemical binding]; other site
550537021374	Mg2+ binding site [ion binding]; other site
550537021375	G-X-G motif; other site
550537021376	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2e-27
550537021377	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 1.1e-11
550537021378	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1e-08
550537021379	2 probable transmembrane helices predicted for SEN4062 by TMHMM2.0 at aa 13-35 and 66-88
550537021380	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
550537021381	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537021382	active site
550537021383	phosphorylation site [posttranslational modification]
550537021384	intermolecular recognition site; other site
550537021385	dimerization interface [polypeptide binding]; other site
550537021386	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537021387	DNA binding site [nucleotide binding]
550537021388	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 5.8e-20
550537021389	HMMPfam hit to PF00072, Response regulator receiver, score 1.3e-45
550537021390	PS00217 Sugar transport proteins signature 2.
550537021391	putative metal dependent hydrolase; Provisional; Region: PRK11598
550537021392	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
550537021393	Sulfatase; Region: Sulfatase; pfam00884
550537021394	HMMPfam hit to PF00884, Sulphatase, score 9.8e-78
550537021395	HMMPfam hit to PF08019, Protein of unknown function DUF1705, score 1.5e-71
550537021396	5 probable transmembrane helices predicted for SEN4064 by TMHMM2.0 at aa 12-34, 49-71, 78-100, 120-142 and 154-176
550537021397	arginine:agmatin antiporter; Provisional; Region: PRK10644
550537021398	11 probable transmembrane helices predicted for SEN4065 by TMHMM2.0 at aa 10-32, 39-61, 94-116, 123-142, 152-173, 228-250, 274-296, 324-341, 356-378, 385-407 and 411-428
550537021399	HMMPfam hit to PF00324, Amino acid permease-associated region, score 1.4e-16
550537021400	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021401	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
550537021402	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537021403	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 1.4e-08
550537021404	PS00041 Bacterial regulatory proteins, araC family signature.
550537021405	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 7.3e-06
550537021406	arginine decarboxylase; Provisional; Region: PRK15029
550537021407	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
550537021408	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
550537021409	homodimer interface [polypeptide binding]; other site
550537021410	pyridoxal 5'-phosphate binding site [chemical binding]; other site
550537021411	catalytic residue [active]
550537021412	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
550537021413	HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal, score 1.8e-66
550537021414	HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major region, score 3.9e-294
550537021415	PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site.
550537021416	HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal, score 8.9e-39
550537021417	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
550537021418	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537021419	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 3e-13
550537021420	PS00041 Bacterial regulatory proteins, araC family signature.
550537021421	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 9.6e-06
550537021422	alpha-galactosidase; Provisional; Region: PRK15076
550537021423	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
550537021424	NAD binding site [chemical binding]; other site
550537021425	sugar binding site [chemical binding]; other site
550537021426	divalent metal binding site [ion binding]; other site
550537021427	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
550537021428	dimer interface [polypeptide binding]; other site
550537021429	HMMPfam hit to PF02056, Glycoside hydrolase, family 4, score 1.2e-241
550537021430	PS01324 Glycosyl hydrolases family 4 signature.
550537021431	melibiose:sodium symporter; Provisional; Region: PRK10429
550537021432	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
550537021433	12 probable transmembrane helices predicted for SEN4071 by TMHMM2.0 at aa 9-31, 36-58, 78-100, 110-132, 145-167, 177-199, 236-258, 268-290, 297-319, 324-346, 378-400 and 410-432
550537021434	PS00872 Sodium:galactoside symporter family signature.
550537021435	fumarate hydratase; Provisional; Region: PRK15389
550537021436	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
550537021437	Fumarase C-terminus; Region: Fumerase_C; pfam05683
550537021438	HMMPfam hit to PF05683, Fe-S type hydro-lyases tartrate/fumarate beta region, score 8.7e-113
550537021439	PS00163 Fumarate lyases signature.
550537021440	HMMPfam hit to PF05681, Fe-S type hydro-lyases tartrate/fumarate alpha region, score 8.8e-147
550537021441	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021442	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
550537021443	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
550537021444	11 probable transmembrane helices predicted for SEN4073 by TMHMM2.0 at aa 21-43, 53-75, 88-110, 142-164, 171-193, 236-253, 266-288, 303-325, 346-368, 378-400 and 421-443
550537021445	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021446	HMMPfam hit to PF03605, Anaerobic c4-dicarboxylate membrane transporter, score 4.9e-258
550537021447	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
550537021448	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537021449	active site
550537021450	phosphorylation site [posttranslational modification]
550537021451	intermolecular recognition site; other site
550537021452	dimerization interface [polypeptide binding]; other site
550537021453	HMMPfam hit to PF00072, Response regulator receiver, score 1.5e-24
550537021454	sensory histidine kinase DcuS; Provisional; Region: PRK11086
550537021455	PAS domain; Region: PAS; smart00091
550537021456	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537021457	ATP binding site [chemical binding]; other site
550537021458	Mg2+ binding site [ion binding]; other site
550537021459	G-X-G motif; other site
550537021460	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 3.2e-31
550537021461	HMMPfam hit to PF00989, PAS fold, score 3.1e-17
550537021462	2 probable transmembrane helices predicted for SEN4076 by TMHMM2.0 at aa 20-42 and 183-202
550537021463	Note carries a premature stop codon following codon 30; the sequence has been checked and is believed to be correct, similar to many proposed anaerobic dimethyl sulfoxide reductases
550537021464	HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 region, score 1.7e-08
550537021465	HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 4.3e-104
550537021466	HMMPfam hit to PF01568, Molydopterin dinucleotide-binding region, score 2.2e-33
550537021467	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
550537021468	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 2.9e-06
550537021469	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537021470	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
550537021471	HMMPfam hit to PF04976, DMSO reductase anchor subunit (DmsC), score 4.2e-16
550537021472	8 probable transmembrane helices predicted for SEN4079 by TMHMM2.0 at aa 10-32, 39-61, 81-100, 107-129, 139-161, 166-188, 203-221 and 228-250
550537021473	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
550537021474	HMMPfam hit to PF06192, Cytoplasmic chaperone TorD, score 4.5e-56
550537021475	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
550537021476	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
550537021477	SdiA-regulated; Region: SdiA-regulated; cd09971
550537021478	putative active site [active]
550537021479	1 probable transmembrane helix predicted for SEN4082 by TMHMM2.0 at aa 13-35
550537021480	HMMPfam hit to PF06977, SdiA-regulated, score 7.5e-49
550537021481	Note that the similarity to the S. Typhi protein is restricted and suggests that a rearrangement in either S. enteritidis or S. typhi has disrupted these coding sequences. It is not possible to tell which is the original conformation
550537021482	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
550537021483	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537021484	DNA binding residues [nucleotide binding]
550537021485	dimerization interface [polypeptide binding]; other site
550537021486	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1.4e-07
550537021487	AraC family transcriptional regulator; Provisional; Region: PRK15186
550537021488	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537021489	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.3e-11
550537021490	PS00041 Bacterial regulatory proteins, araC family signature.
550537021491	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 0.0016
550537021492	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
550537021493	HMMPfam hit to PF08681, Protein of unknown function DUF1778, score 1.5e-27
550537021494	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537021495	Coenzyme A binding pocket [chemical binding]; other site
550537021496	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 7.1e-05
550537021497	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
550537021498	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
550537021499	active site
550537021500	HMMPfam hit to PF01569, Phosphatidic acid phosphatase type 2-like, score 2.6e-23
550537021501	PS00018 EF-hand calcium-binding domain.
550537021502	PS01157 Class A bacterial acid phosphatases signature.
550537021503	putative transcriptional regulator; Provisional; Region: PRK11640
550537021504	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
550537021505	HMMPfam hit to PF00440, Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal, score 4.2e-06
550537021506	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
550537021507	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
550537021508	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
550537021509	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
550537021510	DsbD alpha interface [polypeptide binding]; other site
550537021511	catalytic residues [active]
550537021512	PS00194 Thioredoxin family active site.
550537021513	HMMPfam hit to PF00085, Thioredoxin domain, score 7.4e-06
550537021514	8 probable transmembrane helices predicted for SEN4093 by TMHMM2.0 at aa 5-22, 170-192, 212-234, 246-268, 297-319, 326-348, 358-380 and 387-409
550537021515	HMMPfam hit to PF02683, Cytochrome c biogenesis protein, transmembrane region, score 2.2e-07
550537021516	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
550537021517	HMMPfam hit to PF03091, Divalent ion tolerance protein, CutA1, score 1.8e-58
550537021518	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
550537021519	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
550537021520	10 probable transmembrane helices predicted for SEN4095 by TMHMM2.0 at aa 7-29, 49-71, 91-113, 123-145, 187-204, 219-238, 245-267, 287-306, 319-341 and 371-393
550537021521	HMMPfam hit to PF03605, Anaerobic c4-dicarboxylate membrane transporter, score 1.2e-198
550537021522	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
550537021523	Aspartase; Region: Aspartase; cd01357
550537021524	active sites [active]
550537021525	tetramer interface [polypeptide binding]; other site
550537021526	HMMPfam hit to PF00206, Fumarate lyase, score 9.9e-180
550537021527	PS00163 Fumarate lyases signature.
550537021528	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
550537021529	3 probable transmembrane helices predicted for SEN4097 by TMHMM2.0 at aa 15-34, 39-61 and 92-114
550537021530	HMMPfam hit to PF04186, FxsA cytoplasmic membrane protein, score 3.8e-60
550537021531	putative transporter; Provisional; Region: PRK11021
550537021532	10 probable transmembrane helices predicted for SEN4098 by TMHMM2.0 at aa 7-29, 44-66, 87-109, 146-168, 181-203, 223-245, 258-280, 314-336, 343-362 and 372-406
550537021533	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021534	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021535	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021536	HMMPfam hit to PF00324, Amino acid permease-associated region, score 0.00022
550537021537	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
550537021538	oligomerisation interface [polypeptide binding]; other site
550537021539	mobile loop; other site
550537021540	roof hairpin; other site
550537021541	HMMPfam hit to PF00166, Chaperonin Cpn10, score 7.9e-42
550537021542	PS00681 Chaperonins cpn10 signature.
550537021543	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
550537021544	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
550537021545	ring oligomerisation interface [polypeptide binding]; other site
550537021546	ATP/Mg binding site [chemical binding]; other site
550537021547	stacking interactions; other site
550537021548	hinge regions; other site
550537021549	HMMPfam hit to PF00118, Chaperonin Cpn60/TCP-1, score 5.5e-192
550537021550	PS00296 Chaperonins cpn60 signature.
550537021551	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
550537021552	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021553	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
550537021554	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537021555	FeS/SAM binding site; other site
550537021556	HMMPfam hit to PF04055, Radical SAM, score 2.6e-08
550537021557	elongation factor P; Validated; Region: PRK00529
550537021558	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
550537021559	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
550537021560	RNA binding site [nucleotide binding]; other site
550537021561	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
550537021562	RNA binding site [nucleotide binding]; other site
550537021563	HMMPfam hit to PF08207, Translation elongation factor, KOW-like, score 5.8e-32
550537021564	HMMPfam hit to PF01132, Translation elongation factor P/YeiP, central, score 3.2e-32
550537021565	HMMPfam hit to PF09285, Elongation factor P, C-terminal, score 4e-35
550537021566	PS01275 Elongation factor P signature.
550537021567	Predicted small secreted protein [Function unknown]; Region: COG5510
550537021568	HMMPfam hit to PF08085, Entericidin EcnAB, score 2.6e-22
550537021569	1 probable transmembrane helix predicted for SEN4105 by TMHMM2.0 at aa 20-42
550537021570	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021571	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
550537021572	HMMPfam hit to PF08085, Entericidin EcnAB, score 1e-20
550537021573	1 probable transmembrane helix predicted for SEN4106 by TMHMM2.0 at aa 7-29
550537021574	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021575	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
550537021576	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537021577	DNA binding residues [nucleotide binding]
550537021578	dimerization interface [polypeptide binding]; other site
550537021579	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1.7e-12
550537021580	PS00622 Bacterial regulatory proteins, luxR family signature.
550537021581	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021582	multidrug efflux system protein; Provisional; Region: PRK11431
550537021583	HMMPfam hit to PF00893, Small multidrug resistance protein, score 2.7e-45
550537021584	4 probable transmembrane helices predicted for SEN4108 by TMHMM2.0 at aa 2-19, 29-48, 55-77 and 87-104
550537021585	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
550537021586	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
550537021587	HMMPfam hit to PF08212, Lipocalin-like, score 2.8e-82
550537021588	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537021589	PS00213 Lipocalin signature.
550537021590	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021591	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
550537021592	Iron-sulfur protein interface; other site
550537021593	proximal quinone binding site [chemical binding]; other site
550537021594	C-subunit interface; other site
550537021595	distal quinone binding site; other site
550537021596	HMMPfam hit to PF02313, Fumarate reductase, D subunit, score 1.3e-82
550537021597	3 probable transmembrane helices predicted for SEN4110 by TMHMM2.0 at aa 13-42, 57-79 and 99-118
550537021598	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537021599	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
550537021600	D-subunit interface [polypeptide binding]; other site
550537021601	Iron-sulfur protein interface; other site
550537021602	proximal quinone binding site [chemical binding]; other site
550537021603	HMMPfam hit to PF02300, Fumarate reductase, subunit C, score 6.6e-98
550537021604	3 probable transmembrane helices predicted for SEN4111 by TMHMM2.0 at aa 28-50, 60-82 and 108-130
550537021605	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
550537021606	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
550537021607	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.00083
550537021608	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537021609	HMMPfam hit to PF00111, Ferredoxin, score 0.063
550537021610	PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature.
550537021611	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
550537021612	L-aspartate oxidase; Provisional; Region: PRK06175
550537021613	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
550537021614	HMMPfam hit to PF02910, Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal, score 5.2e-70
550537021615	HMMPfam hit to PF00890, Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal, score 2.9e-158
550537021616	PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site.
550537021617	poxB regulator PoxA; Provisional; Region: PRK09350
550537021618	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
550537021619	motif 1; other site
550537021620	dimer interface [polypeptide binding]; other site
550537021621	active site
550537021622	motif 2; other site
550537021623	motif 3; other site
550537021624	HMMPfam hit to PF00152, Aminoacyl-tRNA synthetase, class II (D, K and N), score 1.7e-76
550537021625	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
550537021626	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
550537021627	inner membrane transporter YjeM; Provisional; Region: PRK15238
550537021628	12 probable transmembrane helices predicted for SEN4115 by TMHMM2.0 at aa 12-34, 38-57, 95-117, 132-154, 161-183, 208-230, 243-265, 310-332, 364-383, 393-415, 435-457 and 467-484
550537021629	HMMPfam hit to PF00324, Amino acid permease-associated region, score 5.5e-07
550537021630	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
550537021631	3 probable transmembrane helices predicted for SEN4116 by TMHMM2.0 at aa 7-26, 55-72 and 79-98
550537021632	putative mechanosensitive channel protein; Provisional; Region: PRK10929
550537021633	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
550537021634	Mechanosensitive ion channel; Region: MS_channel; pfam00924
550537021635	HMMPfam hit to PF00924, MscS Mechanosensitive ion channel, score 1.1e-79
550537021636	PS01246 Uncharacterized protein family UPF0003 signature.
550537021637	11 probable transmembrane helices predicted for SEN4117 by TMHMM2.0 at aa 475-492, 521-543, 553-575, 596-617, 627-648, 669-691, 696-718, 784-806, 826-848, 879-898 and 908-930
550537021638	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
550537021639	HMMPfam hit to PF02666, Phosphatidylserine decarboxylase-related, score 2.5e-114
550537021640	GTPase RsgA; Reviewed; Region: PRK12288
550537021641	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
550537021642	RNA binding site [nucleotide binding]; other site
550537021643	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
550537021644	GTPase/Zn-binding domain interface [polypeptide binding]; other site
550537021645	GTP/Mg2+ binding site [chemical binding]; other site
550537021646	G4 box; other site
550537021647	G5 box; other site
550537021648	G1 box; other site
550537021649	Switch I region; other site
550537021650	G2 box; other site
550537021651	G3 box; other site
550537021652	Switch II region; other site
550537021653	HMMPfam hit to PF03193, GTPase EngC, score 5.2e-147
550537021654	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021655	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
550537021656	catalytic site [active]
550537021657	putative active site [active]
550537021658	putative substrate binding site [chemical binding]; other site
550537021659	dimer interface [polypeptide binding]; other site
550537021660	HMMPfam hit to PF00929, Exonuclease, RNase T and DNA polymerase III, score 3.5e-38
550537021661	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
550537021662	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
550537021663	substrate binding pocket [chemical binding]; other site
550537021664	membrane-bound complex binding site; other site
550537021665	hinge residues; other site
550537021666	HMMPfam hit to PF00497, Bacterial extracellular solute-binding protein, family 3, score 9.7e-87
550537021667	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
550537021668	epoxyqueuosine reductase; Region: TIGR00276
550537021669	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
550537021670	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0015
550537021671	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537021672	HMMPfam hit to PF08331, Region of unknown function DUF1730, score 7.2e-40
550537021673	putative carbohydrate kinase; Provisional; Region: PRK10565
550537021674	Uncharacterized conserved protein [Function unknown]; Region: COG0062
550537021675	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
550537021676	putative substrate binding site [chemical binding]; other site
550537021677	putative ATP binding site [chemical binding]; other site
550537021678	PS00268 Cecropin family signature.
550537021679	HMMPfam hit to PF03853, YjeF-related protein, N-terminal, score 5e-67
550537021680	HMMPfam hit to PF01256, Carbohydrate kinase, score 4.1e-110
550537021681	PS01049 Uncharacterized protein family UPF0031 signature 1.
550537021682	PS01050 Uncharacterized protein family UPF0031 signature 2.
550537021683	ADP-binding protein; Provisional; Region: PRK10646
550537021684	HMMPfam hit to PF02367, Protein of unknown function UPF0079, ATPase bacteria, score 7.6e-70
550537021685	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021686	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
550537021687	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
550537021688	active site
550537021689	metal binding site [ion binding]; metal-binding site
550537021690	HMMPfam hit to PF01520, Cell wall hydrolase/autolysin, catalytic, score 8e-99
550537021691	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
550537021692	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537021693	ATP binding site [chemical binding]; other site
550537021694	Mg2+ binding site [ion binding]; other site
550537021695	G-X-G motif; other site
550537021696	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
550537021697	ATP binding site [chemical binding]; other site
550537021698	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
550537021699	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 2.2e-10
550537021700	PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature.
550537021701	HMMPfam hit to PF01119, DNA mismatch repair protein, C-terminal, score 5.7e-48
550537021702	HMMPfam hit to PF08676, MutL, C-terminal, dimerisation, score 2.9e-25
550537021703	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
550537021704	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
550537021705	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021706	HMMPfam hit to PF01715, tRNA isopentenyltransferase, score 5.6e-159
550537021707	bacterial Hfq-like; Region: Hfq; cd01716
550537021708	hexamer interface [polypeptide binding]; other site
550537021709	Sm1 motif; other site
550537021710	RNA binding site [nucleotide binding]; other site
550537021711	Sm2 motif; other site
550537021712	HMMPfam hit to PF01423, Like-Sm ribonucleoprotein, core, score 3.9e-12
550537021713	GTPase HflX; Provisional; Region: PRK11058
550537021714	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
550537021715	HflX GTPase family; Region: HflX; cd01878
550537021716	G1 box; other site
550537021717	GTP/Mg2+ binding site [chemical binding]; other site
550537021718	Switch I region; other site
550537021719	G2 box; other site
550537021720	G3 box; other site
550537021721	Switch II region; other site
550537021722	G4 box; other site
550537021723	G5 box; other site
550537021724	HMMPfam hit to PF01926, GTP-binding protein, HSR1-related, score 1.4e-39
550537021725	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021726	FtsH protease regulator HflK; Provisional; Region: PRK10930
550537021727	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
550537021728	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
550537021729	1 probable transmembrane helix predicted for SEN4130 by TMHMM2.0 at aa 78-100
550537021730	HMMPfam hit to PF01145, Band 7 protein, score 1.1e-54
550537021731	FtsH protease regulator HflC; Provisional; Region: PRK11029
550537021732	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
550537021733	1 probable transmembrane helix predicted for SEN4131 by TMHMM2.0 at aa 5-23
550537021734	HMMPfam hit to PF01145, Band 7 protein, score 2.4e-64
550537021735	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
550537021736	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
550537021737	GDP-binding site [chemical binding]; other site
550537021738	ACT binding site; other site
550537021739	IMP binding site; other site
550537021740	HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 0
550537021741	PS01266 Adenylosuccinate synthetase GTP-binding site.
550537021742	PS00513 Adenylosuccinate synthetase active site.
550537021743	Predicted transcriptional regulator [Transcription]; Region: COG1959
550537021744	transcriptional repressor NsrR; Provisional; Region: PRK11014
550537021745	HMMPfam hit to PF02082, Transcriptional regulator, Rrf2, score 3.8e-46
550537021746	exoribonuclease R; Provisional; Region: PRK11642
550537021747	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
550537021748	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
550537021749	RNB domain; Region: RNB; pfam00773
550537021750	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
550537021751	RNA binding site [nucleotide binding]; other site
550537021752	HMMPfam hit to PF08461, Ribonuclease R winged-helix domain, score 5.7e-24
550537021753	HMMPfam hit to PF08206, Ribonuclease B, OB region N-terminal, score 5e-29
550537021754	HMMPfam hit to PF08206, Ribonuclease B, OB region N-terminal, score 0.00024
550537021755	HMMPfam hit to PF00773, Ribonuclease II and R, score 2.9e-155
550537021756	PS01175 Ribonuclease II family signature.
550537021757	HMMPfam hit to PF00575, S1, RNA binding, score 6.2e-22
550537021758	PS00017 ATP/GTP-binding site motif A (P-loop).
550537021759	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
550537021760	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
550537021761	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
550537021762	HMMPfam hit to PF08032, RNA 2-O ribose methyltransferase, substrate binding, score 6e-22
550537021763	HMMPfam hit to PF00588, tRNA/rRNA methyltransferase, SpoU, score 4.4e-64
550537021764	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
550537021765	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
550537021766	HMMPfam hit to PF04012, PspA/IM30, score 2.5e-69
550537021767	Ion channel; Region: Ion_trans_2; pfam07885
550537021768	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
550537021769	3 probable transmembrane helices predicted for SEN4138 by TMHMM2.0 at aa 15-37, 44-66 and 81-100
550537021770	HMMPfam hit to PF07885, Ion transport 2, score 2.8e-10
550537021771	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
550537021772	Predicted membrane protein [Function unknown]; Region: COG3766
550537021773	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
550537021774	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
550537021775	HMMPfam hit to PF03994, Protein of unknown function DUF350, score 5.4e-21
550537021776	4 probable transmembrane helices predicted for SEN4140 by TMHMM2.0 at aa 6-28, 48-70, 75-97 and 109-131
550537021777	HMMPfam hit to PF03994, Protein of unknown function DUF350, score 2.9e-16
550537021778	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021779	Predicted integral membrane protein [Function unknown]; Region: COG5463
550537021780	HMMPfam hit to PF06693, Protein of unknown function DUF1190, score 2.1e-173
550537021781	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
550537021782	HMMPfam hit to PF03738, Glutathionylspermidine synthase, score 2.7e-249
550537021783	PS00107 Protein kinases ATP-binding region signature.
550537021784	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
550537021785	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
550537021786	FAD binding site [chemical binding]; other site
550537021787	substrate binding site [chemical binding]; other site
550537021788	catalytic residues [active]
550537021789	HMMPfam hit to PF02771, Acyl-CoA dehydrogenase, N-terminal, score 1.3e-41
550537021790	HMMPfam hit to PF02770, Acyl-CoA dehydrogenase/oxidase, central region, score 1.6e-13
550537021791	PS00072 Acyl-CoA dehydrogenases signature 1.
550537021792	HMMPfam hit to PF00441, Acyl-CoA oxidase/dehydrogenase, type 1, score 9.2e-34
550537021793	PS00073 Acyl-CoA dehydrogenases signature 2.
550537021794	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537021795	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 1.2e-47
550537021796	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
550537021797	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 1.5e-05
550537021798	1 probable transmembrane helix predicted for SEN4145 by TMHMM2.0 at aa 13-32
550537021799	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021800	esterase; Provisional; Region: PRK10566
550537021801	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
550537021802	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
550537021803	transcriptional repressor UlaR; Provisional; Region: PRK13509
550537021804	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
550537021805	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
550537021806	HMMPfam hit to PF00455, Bacterial regulatory protein, DeoR, score 5.9e-66
550537021807	HMMPfam hit to PF08220, Bacterial regulatory protein, DeoR N-terminal, score 6e-26
550537021808	PS00894 Bacterial regulatory proteins, deoR family signature.
550537021809	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
550537021810	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
550537021811	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021812	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
550537021813	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
550537021814	HMMPfam hit to PF04215,  sugar-specific permease, SgaT/UlaA, score 1.1e-278
550537021815	10 probable transmembrane helices predicted for SEN4149 by TMHMM2.0 at aa 15-34, 41-63, 100-122, 143-172, 233-252, 264-286, 306-328, 340-362, 377-399 and 424-446
550537021816	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537021817	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021818	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
550537021819	active site
550537021820	P-loop; other site
550537021821	phosphorylation site [posttranslational modification]
550537021822	HMMPfam hit to PF02302, Phosphotransferase system, lactose/cellobiose-specific IIB subunit, score 8.9e-34
550537021823	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537021824	active site
550537021825	phosphorylation site [posttranslational modification]
550537021826	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 1.3e-74
550537021827	PS00372 PTS EIIA domains phosphorylation site signature 2.
550537021828	PS00387 Inorganic pyrophosphatase signature.
550537021829	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
550537021830	active site
550537021831	dimer interface [polypeptide binding]; other site
550537021832	magnesium binding site [ion binding]; other site
550537021833	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase, core, score 4.3e-62
550537021834	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
550537021835	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
550537021836	AP (apurinic/apyrimidinic) site pocket; other site
550537021837	DNA interaction; other site
550537021838	Metal-binding active site; metal-binding site
550537021839	HMMPfam hit to PF01261, Xylose isomerase-type TIM barrel, score 6.4e-44
550537021840	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
550537021841	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
550537021842	intersubunit interface [polypeptide binding]; other site
550537021843	active site
550537021844	Zn2+ binding site [ion binding]; other site
550537021845	HMMPfam hit to PF00596, Class II aldolase/adducin, N-terminal, score 5.4e-99
550537021846	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
550537021847	HMMPfam hit to PF07338, Protein of unknown function DUF1471, score 1.1e-29
550537021848	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
550537021849	HMMPfam hit to PF01250, Ribosomal protein S6, score 2.2e-50
550537021850	PS01048 Ribosomal protein S6 signature.
550537021851	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
550537021852	dimer interface [polypeptide binding]; other site
550537021853	ssDNA binding site [nucleotide binding]; other site
550537021854	tetramer (dimer of dimers) interface [polypeptide binding]; other site
550537021855	HMMPfam hit to PF00436, Primosome PriB/single-strand DNA-binding, score 1.6e-16
550537021856	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
550537021857	HMMPfam hit to PF01084, Ribosomal protein S18, score 1.3e-32
550537021858	PS00057 Ribosomal protein S18 signature.
550537021859	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
550537021860	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
550537021861	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
550537021862	HMMPfam hit to PF01281, Ribosomal protein L9, score 6.5e-27
550537021863	PS00651 Ribosomal protein L9 signature.
550537021864	HMMPfam hit to PF03948, Ribosomal protein L9, score 4.6e-45
550537021865	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
550537021866	EamA-like transporter family; Region: EamA; pfam00892
550537021867	10 probable transmembrane helices predicted for SEN4161 by TMHMM2.0 at aa 13-34, 54-72, 85-107, 117-134, 141-163, 173-192, 204-226, 231-253, 258-280 and 284-303
550537021868	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 5.3e-13
550537021869	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 2.9e-12
550537021870	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
550537021871	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
550537021872	HMMPfam hit to PF04225, Opacity-associated protein A, score 1.2e-56
550537021873	HMMPfam hit to PF08525, Opacity-associated protein A, N-terminal, score 1.6e-08
550537021874	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
550537021875	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
550537021876	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
550537021877	HMMPfam hit to PF01346, Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal, score 2.8e-06
550537021878	HMMPfam hit to PF00254, Peptidyl-prolyl cis-trans isomerase, FKBP-type, score 7.9e-47
550537021879	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
550537021880	PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2.
550537021881	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
550537021882	HMMPfam hit to PF00324, Amino acid permease-associated region, score 2.3e-170
550537021883	12 probable transmembrane helices predicted for SEN4164 by TMHMM2.0 at aa 27-44, 49-71, 104-126, 136-158, 165-187, 210-232, 252-274, 289-311, 347-369, 374-396, 417-436 and 441-460
550537021884	PS00218 Amino acid permeases signature.
550537021885	DKNYY family; Region: DKNYY; pfam13644
550537021886	1 probable transmembrane helix predicted for SEN4166 by TMHMM2.0 at aa 7-29
550537021887	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021888	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
550537021889	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
550537021890	Hemerythrin-like domain; Region: Hr-like; cd12108
550537021891	Fe binding site [ion binding]; other site
550537021892	HMMPfam hit to PF01814, Hemerythrin HHE cation binding region, score 0.00018
550537021893	HMMPfam hit to PF01814, Hemerythrin HHE cation binding region, score 1.4e-06
550537021894	HMMPfam hit to PF04405, Protein of unknown function DUF542, ScdA N-terminal, score 2.9e-37
550537021895	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
550537021896	EamA-like transporter family; Region: EamA; pfam00892
550537021897	10 probable transmembrane helices predicted for SEN4168 by TMHMM2.0 at aa 5-25, 35-52, 64-86, 91-113, 120-142, 152-174, 195-217, 232-254, 259-281 and 286-308
550537021898	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021899	HMMPfam hit to PF00892, Protein of unknown function DUF6, transmembrane, score 8.1e-09
550537021900	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
550537021901	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
550537021902	NADP binding site [chemical binding]; other site
550537021903	HMMPfam hit to PF05368, NmrA-like, score 1.6e-09
550537021904	Predicted transcriptional regulators [Transcription]; Region: COG1733
550537021905	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
550537021906	HMMPfam hit to PF01638, Helix-turn-helix, HxlR type, score 6.9e-53
550537021907	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
550537021908	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
550537021909	active site
550537021910	metal binding site [ion binding]; metal-binding site
550537021911	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
550537021912	HMMPfam hit to PF02872, 5'-Nucleotidase, C-terminal, score 3.6e-65
550537021913	HMMPfam hit to PF00149, Metallophosphoesterase, score 8.1e-20
550537021914	PS00786 5'-nucleotidase signature 2.
550537021915	PS00785 5'-nucleotidase signature 1.
550537021916	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
550537021917	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
550537021918	active site
550537021919	HMMPfam hit to PF00459, Inositol monophosphatase, score 3.9e-75
550537021920	PS00629 Inositol monophosphatase family signature 1.
550537021921	PS00630 Inositol monophosphatase family signature 2.
550537021922	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
550537021923	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
550537021924	HMMPfam hit to PF06526, Protein of unknown function DUF1107, score 2.8e-47
550537021925	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
550537021926	Domain of unknown function DUF21; Region: DUF21; pfam01595
550537021927	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
550537021928	Transporter associated domain; Region: CorC_HlyC; smart01091
550537021929	HMMPfam hit to PF03471, Transporter-associated region, score 1.1e-24
550537021930	HMMPfam hit to PF00571, Cystathionine beta-synthase, core, score 1.6e-15
550537021931	HMMPfam hit to PF01595, Protein of unknown function DUF21, score 1.4e-71
550537021932	4 probable transmembrane helices predicted for SEN4176 by TMHMM2.0 at aa 5-27, 58-80, 100-117 and 144-162
550537021933	methionine sulfoxide reductase A; Provisional; Region: PRK00058
550537021934	HMMPfam hit to PF01625, Methionine sulphoxide reductase A, score 4.2e-106
550537021935	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
550537021936	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
550537021937	Surface antigen; Region: Bac_surface_Ag; pfam01103
550537021938	HMMPfam hit to PF07244, Surface antigen variable number, score 4.3e-11
550537021939	HMMPfam hit to PF01103, Bacterial surface antigen (D15), score 8.4e-80
550537021940	PS00213 Lipocalin signature.
550537021941	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
550537021942	Family of unknown function (DUF490); Region: DUF490; pfam04357
550537021943	1 probable transmembrane helix predicted for SEN4179 by TMHMM2.0 at aa 7-29
550537021944	PS00213 Lipocalin signature.
550537021945	HMMPfam hit to PF04357, Protein of unknown function DUF490, score 8.6e-165
550537021946	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
550537021947	putative active site pocket [active]
550537021948	dimerization interface [polypeptide binding]; other site
550537021949	putative catalytic residue [active]
550537021950	HMMPfam hit to PF03674, Protein of unknown function UPF0131, score 3.8e-51
550537021951	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537021952	D-galactonate transporter; Region: 2A0114; TIGR00893
550537021953	putative substrate translocation pore; other site
550537021954	12 probable transmembrane helices predicted for SEN4181 by TMHMM2.0 at aa 7-26, 41-63, 76-93, 97-116, 137-154, 164-186, 215-237, 252-273, 280-302, 307-329, 342-364 and 374-393
550537021955	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537021956	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 1.1e-52
550537021957	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
550537021958	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
550537021959	active site
550537021960	HMMPfam hit to PF07969, Amidohydrolase 3, score 0.00017
550537021961	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
550537021962	dimer interface [polypeptide binding]; other site
550537021963	substrate binding site [chemical binding]; other site
550537021964	metal binding sites [ion binding]; metal-binding site
550537021965	HMMPfam hit to PF00719, Inorganic pyrophosphatase, score 1.4e-61
550537021966	PS00387 Inorganic pyrophosphatase signature.
550537021967	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
550537021968	AMP binding site [chemical binding]; other site
550537021969	metal binding site [ion binding]; metal-binding site
550537021970	active site
550537021971	HMMPfam hit to PF00316, Inositol phosphatase/fructose-1,6-bisphosphatase, score 6.1e-219
550537021972	PS00124 Fructose-1-6-bisphosphatase active site.
550537021973	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
550537021974	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
550537021975	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
550537021976	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
550537021977	HMMPfam hit to PF01225, Mur ligase, N-terminal, score 5.4e-31
550537021978	HMMPfam hit to PF08245, Mur ligase, central, score 1.5e-09
550537021979	HMMPfam hit to PF02875, Mur ligase, C-terminal, score 4.2e-07
550537021980	hypothetical protein; Provisional; Region: PRK05255
550537021981	HMMPfam hit to PF04751, Protein of unknown function DUF615, score 5.8e-117
550537021982	peptidase PmbA; Provisional; Region: PRK11040
550537021983	HMMPfam hit to PF01523, Peptidase U62, modulator of DNA gyrase, score 3.7e-101
550537021984	cytochrome b562; Provisional; Region: PRK15058
550537021985	1 probable transmembrane helix predicted for SEN4188 by TMHMM2.0 at aa 5-23
550537021986	HMMPfam hit to PF07361, Cytochrome b562, score 3.6e-58
550537021987	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
550537021988	HMMPfam hit to PF00874, PRD, score 2.5e-16
550537021989	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
550537021990	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
550537021991	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
550537021992	6 probable transmembrane helices predicted for SEN4192 by TMHMM2.0 at aa 2-24, 55-77, 111-133, 143-165, 177-199 and 214-232
550537021993	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
550537021994	6 probable transmembrane helices predicted for SEN4193 by TMHMM2.0 at aa 15-37, 57-74, 84-106, 111-133, 165-187 and 194-213
550537021995	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
550537021996	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
550537021997	active site
550537021998	HMMPfam hit to PF01979, Amidohydrolase 1, score 0.00015
550537021999	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
550537022000	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
550537022001	HMMPfam hit to PF01212, Aromatic amino acid beta-eliminating lyase/threonine aldolase, score 3.9e-05
550537022002	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
550537022003	HMMPfam hit to PF07071, Protein of unknown function DUF1341, score 1.8e-163
550537022004	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
550537022005	HTH domain; Region: HTH_11; pfam08279
550537022006	Mga helix-turn-helix domain; Region: Mga; pfam05043
550537022007	PRD domain; Region: PRD; pfam00874
550537022008	PRD domain; Region: PRD; pfam00874
550537022009	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
550537022010	active site
550537022011	P-loop; other site
550537022012	phosphorylation site [posttranslational modification]
550537022013	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
550537022014	active site
550537022015	phosphorylation site [posttranslational modification]
550537022016	HMMPfam hit to PF08279, Helix-turn-helix, type 11, score 1.2e-15
550537022017	PS00894 Bacterial regulatory proteins, deoR family signature.
550537022018	HMMPfam hit to PF05043, M trans-acting positive regulator, score 7.4e-06
550537022019	HMMPfam hit to PF00874, PRD, score 1.4e-15
550537022020	HMMPfam hit to PF00874, PRD, score 3.5e-16
550537022021	HMMPfam hit to PF00359, Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2, score 4e-05
550537022022	PS00372 PTS EIIA domains phosphorylation site signature 2.
550537022023	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
550537022024	HMMPfam hit to PF04221, RelB antitoxin, score 9.4e-14
550537022025	PS00215 Mitochondrial energy transfer proteins signature.
550537022026	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
550537022027	HMMPfam hit to PF05016, Plasmid stabilization system, score 1.3e-16
550537022028	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
550537022029	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537022030	FeS/SAM binding site; other site
550537022031	PS01087 Radical activating enzymes signature.
550537022032	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
550537022033	ATP cone domain; Region: ATP-cone; pfam03477
550537022034	Class III ribonucleotide reductase; Region: RNR_III; cd01675
550537022035	effector binding site; other site
550537022036	active site
550537022037	Zn binding site [ion binding]; other site
550537022038	glycine loop; other site
550537022039	HMMPfam hit to PF01228, Formate C-acetyltransferase glycine radical, score 2.5e-57
550537022040	PS00850 Glycine radical signature.
550537022041	HMMPfam hit to PF03477, ATP-cone, score 8.3e-31
550537022042	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
550537022043	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
550537022044	Ca binding site [ion binding]; other site
550537022045	active site
550537022046	catalytic site [active]
550537022047	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
550537022048	HMMPfam hit to PF00128, Glycosyl hydrolase, family 13, catalytic region, score 3.9e-144
550537022049	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
550537022050	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
550537022051	active site turn [active]
550537022052	phosphorylation site [posttranslational modification]
550537022053	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
550537022054	10 probable transmembrane helices predicted for SEN4204A by TMHMM2.0 at aa 109-131, 159-181, 188-210, 230-247, 259-281, 301-323, 344-363, 373-395, 408-430 and 440-462
550537022055	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 6.6e-29
550537022056	HMMPfam hit to PF00367, Phosphotransferase system, EIIB, score 7.7e-08
550537022057	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
550537022058	trehalose repressor; Provisional; Region: treR; PRK09492
550537022059	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537022060	DNA binding site [nucleotide binding]
550537022061	domain linker motif; other site
550537022062	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
550537022063	dimerization interface [polypeptide binding]; other site
550537022064	ligand binding site [chemical binding]; other site
550537022065	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 3.1e-05
550537022066	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 8.5e-13
550537022067	PS00356 Bacterial regulatory proteins, lacI family signature.
550537022068	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
550537022069	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
550537022070	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
550537022071	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
550537022072	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
550537022073	Soluble P-type ATPase [General function prediction only]; Region: COG4087
550537022074	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
550537022075	HMMPfam hit to PF00690, ATPase, P-type cation-transporter, N-terminal, score 1.3e-16
550537022076	8 probable transmembrane helices predicted for SEN4207 by TMHMM2.0 at aa 122-141, 295-314, 324-346, 714-736, 773-795, 808-827, 842-864 and 869-891
550537022077	HMMPfam hit to PF00122, E1-E2 ATPase-associated region, score 5.3e-95
550537022078	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.6e-16
550537022079	PS00154 E1-E2 ATPases phosphorylation site.
550537022080	Transposase; Region: HTH_Tnp_1; cl17663
550537022081	2 probable transmembrane helices predicted for SEN4208 by TMHMM2.0 at aa 59-78 and 82-101
550537022082	HMMPfam hit to PF01527, Transposase IS3/IS911, score 9.4e-08
550537022083	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
550537022084	homotrimer interaction site [polypeptide binding]; other site
550537022085	putative active site [active]
550537022086	HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 2.3e-63
550537022087	PS01094 Uncharacterized protein family UPF0076 signature.
550537022088	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
550537022089	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
550537022090	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
550537022091	HMMPfam hit to PF02748, Aspartate transcarbamylase regulatory subunit, score 6e-30
550537022092	HMMPfam hit to PF01948, Aspartate transcarbamylase regulatory subunit, score 9.9e-66
550537022093	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
550537022094	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
550537022095	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
550537022096	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region, score 4.9e-65
550537022097	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding, score 3.6e-78
550537022098	PS00097 Aspartate and ornithine carbamoyltransferases signature.
550537022099	pyrBI operon leader peptide; Provisional; Region: PRK10224
550537022100	HMMPfam hit to PF08052, PyrBI operon leader peptide, score 5.2e-14
550537022101	Arginine repressor [Transcription]; Region: ArgR; COG1438
550537022102	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
550537022103	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
550537022104	HMMPfam hit to PF02863, Arginine repressor, score 9.2e-27
550537022105	HMMPfam hit to PF01316, Arginine repressor, score 3.6e-10
550537022106	Predicted membrane protein [Function unknown]; Region: COG1288
550537022107	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
550537022108	HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 2.5e-151
550537022109	11 probable transmembrane helices predicted for SEN4214 by TMHMM2.0 at aa 7-29, 76-98, 121-140, 162-184, 205-222, 263-285, 290-307, 322-339, 371-393, 413-435 and 442-464
550537022110	ornithine carbamoyltransferase; Validated; Region: PRK02102
550537022111	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
550537022112	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
550537022113	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region, score 2.5e-86
550537022114	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding, score 3e-78
550537022115	PS00097 Aspartate and ornithine carbamoyltransferases signature.
550537022116	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
550537022117	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
550537022118	putative substrate binding site [chemical binding]; other site
550537022119	nucleotide binding site [chemical binding]; other site
550537022120	nucleotide binding site [chemical binding]; other site
550537022121	homodimer interface [polypeptide binding]; other site
550537022122	HMMPfam hit to PF00696, Aspartate/glutamate/uridylate kinase, score 1.7e-85
550537022123	arginine deiminase; Provisional; Region: PRK01388
550537022124	HMMPfam hit to PF02274, Amidinotransferase, score 1.6e-177
550537022125	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
550537022126	HMMPfam hit to PF04074, Conserved hypothetical protein CHP00022, score 7.1e-72
550537022127	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
550537022128	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
550537022129	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
550537022130	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region, score 1.5e-98
550537022131	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding, score 1.6e-82
550537022132	PS00097 Aspartate and ornithine carbamoyltransferases signature.
550537022133	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
550537022134	RNase E inhibitor protein; Provisional; Region: PRK11191
550537022135	HMMPfam hit to PF06877, Protein of unknown function DUF1260, score 1.2e-47
550537022136	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
550537022137	active site
550537022138	dinuclear metal binding site [ion binding]; other site
550537022139	dimerization interface [polypeptide binding]; other site
550537022140	HMMPfam hit to PF06175, tRNA--hydroxylase, score 5.7e-194
550537022141	Note that the framshift occurs within a homopolymeric tract which could be a site for programmed ribosomal frameshifting
550537022142	homopolymeric tract in which a frameshift in CDS SEN4224 occurs
550537022143	Signal peptide predicted for SEN4225 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 22 and 23
550537022144	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
550537022145	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537022146	Coenzyme A binding pocket [chemical binding]; other site
550537022147	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 9.4e-20
550537022148	Predicted membrane protein [Function unknown]; Region: COG4269
550537022149	HMMPfam hit to PF05987, Protein of unknown function DUF898, transmembrane bacterial, score 5.5e-229
550537022150	8 probable transmembrane helices predicted for SEN4227 by TMHMM2.0 at aa 24-46, 67-89, 99-121, 142-164, 169-191, 229-251, 281-303 and 324-346
550537022151	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
550537022152	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
550537022153	HIGH motif; other site
550537022154	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
550537022155	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
550537022156	active site
550537022157	KMSKS motif; other site
550537022158	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
550537022159	tRNA binding surface [nucleotide binding]; other site
550537022160	anticodon binding site; other site
550537022161	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
550537022162	HMMPfam hit to PF08264, Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding, score 6e-68
550537022163	HMMPfam hit to PF00133, Aminoacyl-tRNA synthetase, class Ia, score 0
550537022164	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537022165	DNA polymerase III subunit chi; Validated; Region: PRK05728
550537022166	HMMPfam hit to PF04364, DNA polymerase III chi subunit, HolC, score 2.3e-79
550537022167	multifunctional aminopeptidase A; Provisional; Region: PRK00913
550537022168	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
550537022169	interface (dimer of trimers) [polypeptide binding]; other site
550537022170	Substrate-binding/catalytic site; other site
550537022171	Zn-binding sites [ion binding]; other site
550537022172	HMMPfam hit to PF00883, Peptidase M17, leucyl aminopeptidase, C-terminal, score 1.9e-208
550537022173	PS00631 Cytosol aminopeptidase signature.
550537022174	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022175	HMMPfam hit to PF02789, Peptidase M17, leucyl aminopeptidase, N-terminal, score 1.1e-43
550537022176	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
550537022177	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
550537022178	HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ, score 4.2e-77
550537022179	6 probable transmembrane helices predicted for SEN4232 by TMHMM2.0 at aa 17-39, 54-76, 97-119, 267-289, 296-313 and 328-348
550537022180	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
550537022181	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
550537022182	HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ, score 2.1e-93
550537022183	6 probable transmembrane helices predicted for SEN4233 by TMHMM2.0 at aa 10-32, 64-83, 103-125, 279-301, 305-322 and 329-351
550537022184	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
550537022185	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
550537022186	DNA binding site [nucleotide binding]
550537022187	domain linker motif; other site
550537022188	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
550537022189	putative dimerization interface [polypeptide binding]; other site
550537022190	putative ligand binding site [chemical binding]; other site
550537022191	HMMPfam hit to PF00532, Periplasmic binding protein/LacI transcriptional regulator, score 3.6e-08
550537022192	HMMPfam hit to PF00356, Bacterial regulatory protein, LacI, score 4.7e-11
550537022193	PS00356 Bacterial regulatory proteins, lacI family signature.
550537022194	gluconate transporter; Region: gntP; TIGR00791
550537022195	fructuronate transporter; Provisional; Region: PRK10034; cl15264
550537022196	11 probable transmembrane helices predicted for SEN4235 by TMHMM2.0 at aa 20-42, 66-88, 92-114, 138-160, 186-208, 221-243, 258-279, 291-313, 317-339, 346-368 and 383-405
550537022197	HMMPfam hit to PF02447, Gluconate transporter, score 3.2e-246
550537022198	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
550537022199	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
550537022200	NADP binding site [chemical binding]; other site
550537022201	homodimer interface [polypeptide binding]; other site
550537022202	active site
550537022203	HMMPfam hit to PF00106, Short-chain dehydrogenase/reductase SDR, score 8.1e-34
550537022204	PS00061 Short-chain dehydrogenases/reductases family signature.
550537022205	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
550537022206	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
550537022207	putative NAD(P) binding site [chemical binding]; other site
550537022208	catalytic Zn binding site [ion binding]; other site
550537022209	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 5.1e-33
550537022210	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 5.9e-42
550537022211	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
550537022212	ATP-binding site [chemical binding]; other site
550537022213	Gluconate-6-phosphate binding site [chemical binding]; other site
550537022214	Shikimate kinase; Region: SKI; pfam01202
550537022215	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022216	HMMPfam hit to PF01202, Shikimate kinase, score 3.1e-06
550537022217	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
550537022218	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
550537022219	putative NAD(P) binding site [chemical binding]; other site
550537022220	putative substrate binding site [chemical binding]; other site
550537022221	catalytic Zn binding site [ion binding]; other site
550537022222	structural Zn binding site [ion binding]; other site
550537022223	dimer interface [polypeptide binding]; other site
550537022224	HMMPfam hit to PF00107, Alcohol dehydrogenase, zinc-binding, score 2.5e-33
550537022225	PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature.
550537022226	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like, score 3.8e-40
550537022227	PS00059 Zinc-containing alcohol dehydrogenases signature.
550537022228	PS00190 Cytochrome c family heme-binding site signature.
550537022229	Salmonella Pathogenicity Island 10: SPI-10 (degenerate)
550537022231	Note this CDS carries a premature stop codon and appears to have suffered a deletion event removing the C-terminal region
550537022232	Predicted transcriptional regulator [Transcription]; Region: COG3905
550537022233	HMMPfam hit to PF01402, CopG-like DNA-binding, score 1.6e-06
550537022234	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
550537022235	HMMPfam hit to PF07362, Post-segregation antitoxin CcdA, score 4.1e-19
550537022236	CcdB protein; Region: CcdB; pfam01845
550537022237	HMMPfam hit to PF01845, CcdB protein, score 2.1e-18
550537022239	Note this CDS lacks an appropriate N-terminus and carries a frameshift mutation following codon 70
550537022240	HMMPfam hit to PF00665, Integrase, catalytic core, score 8.5e-43
550537022241	HTH-like domain; Region: HTH_21; pfam13276
550537022242	HMMPfam hit to PF01527, Transposase IS3/IS911, score 7.6e-07
550537022243	fimbrial operon sef
550537022244	fimbrial protein SefA; Provisional; Region: PRK15228
550537022245	HMMPfam hit to PF06443, SEF14-like adhesin, score 2e-124
550537022246	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022247	putative fimbrial chaperone protein SefB; Provisional; Region: PRK15233
550537022248	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537022249	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537022250	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 9.9e-68
550537022251	PS00635 Gram-negative pili assembly chaperone signature.
550537022252	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 7.3e-26
550537022253	outer membrane fimbrial usher protein SefC; Provisional; Region: PRK15235
550537022254	PapC N-terminal domain; Region: PapC_N; pfam13954
550537022255	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537022256	PapC C-terminal domain; Region: PapC_C; pfam13953
550537022257	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537022258	fimbrial adhesin protein SefD; Provisional; Region: PRK15231
550537022259	HMMPfam hit to PF05775, Enterobacteria AfaD invasin, score 1e-81
550537022260	1 probable transmembrane helix predicted for SEN4250 by TMHMM2.0 at aa 7-29
550537022261	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
550537022262	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537022263	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 1.5e-10
550537022264	PS00041 Bacterial regulatory proteins, araC family signature.
550537022265	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537022266	DNA binding residues [nucleotide binding]
550537022267	dimerization interface [polypeptide binding]; other site
550537022268	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 3.3e-06
550537022269	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
550537022270	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
550537022271	catalytic residues [active]
550537022272	hinge region; other site
550537022273	alpha helical domain; other site
550537022274	HMMPfam hit to PF01323, DSBA oxidoreductase, score 2.7e-39
550537022275	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
550537022276	SdiA-regulated; Region: SdiA-regulated; cd09971
550537022277	putative active site [active]
550537022278	1 probable transmembrane helix predicted for SEN4254 by TMHMM2.0 at aa 12-34
550537022279	HMMPfam hit to PF06977, SdiA-regulated, score 5e-42
550537022280	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
550537022281	DNA-binding interface [nucleotide binding]; DNA binding site
550537022282	HMMPfam hit to PF01527, Transposase IS3/IS911, score 9.2e-28
550537022283	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
550537022284	HNH endonuclease; Region: HNH_2; pfam13391
550537022285	hypothetical protein; Provisional; Region: PRK12378
550537022286	HMMPfam hit to PF01709, Protein of unknown function DUF28, score 8.7e-125
550537022287	Methyltransferase domain; Region: Methyltransf_23; pfam13489
550537022288	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537022289	S-adenosylmethionine binding site [chemical binding]; other site
550537022290	Methyltransferase domain; Region: Methyltransf_31; pfam13847
550537022291	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537022292	S-adenosylmethionine binding site [chemical binding]; other site
550537022293	HMMPfam hit to PF08242, Methyltransferase type 12, score 2.1e-11
550537022294	HMMPfam hit to PF08241, Methyltransferase type 11, score 8.1e-21
550537022295	hypothetical protein; Provisional; Region: PRK13687
550537022296	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
550537022297	HMMPfam hit to PF06353, Protein of unknown function DUF1062, score 6.7e-118
550537022298	Uncharacterized conserved protein [Function unknown]; Region: COG3439
550537022299	1 probable transmembrane helix predicted for SEN4265 by TMHMM2.0 at aa 7-24
550537022300	HMMPfam hit to PF03625, Protein of unknown function DUF302, score 9e-20
550537022301	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
550537022302	HMMPfam hit to PF01738, Dienelactone hydrolase, score 3.1e-06
550537022303	PS00120 Lipases, serine active site.
550537022304	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
550537022305	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
550537022306	DNA-binding site [nucleotide binding]; DNA binding site
550537022307	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
550537022308	HMMPfam hit to PF00392, Bacterial regulatory protein GntR, HTH, score 9.2e-31
550537022309	PS00043 Bacterial regulatory proteins, gntR family signature.
550537022310	HMMPfam hit to PF07729, GntR, C-terminal, score 6.8e-38
550537022311	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
550537022312	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
550537022313	active site
550537022314	HIGH motif; other site
550537022315	dimer interface [polypeptide binding]; other site
550537022316	KMSKS motif; other site
550537022317	HMMPfam hit to PF00579, Aminoacyl-tRNA synthetase, class Ib, score 4.6e-69
550537022318	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
550537022319	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
550537022320	HMMPfam hit to PF05638, Virulence factor for secretion apparatus, score 1.3e-51
550537022321	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
550537022322	aspartate racemase; Region: asp_race; TIGR00035
550537022323	HMMPfam hit to PF01177, Asp/Glu/hydantoin racemase, score 1.9e-28
550537022324	PS00923 Aspartate and glutamate racemases signature 1.
550537022325	PS00924 Aspartate and glutamate racemases signature 2.
550537022326	cell density-dependent motility repressor; Provisional; Region: PRK10082
550537022327	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
550537022328	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
550537022329	dimerization interface [polypeptide binding]; other site
550537022330	HMMPfam hit to PF03466, LysR, substrate-binding, score 3.4e-23
550537022331	HMMPfam hit to PF00126, Bacterial regulatory protein, LysR, score 2.9e-13
550537022332	PS00044 Bacterial regulatory proteins, lysR family signature.
550537022333	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
550537022334	isoaspartyl dipeptidase; Provisional; Region: PRK10657
550537022335	dimer interface [polypeptide binding]; other site
550537022336	active site
550537022337	HMMPfam hit to PF01979, Amidohydrolase 1, score 6.1e-06
550537022338	hypothetical protein; Provisional; Region: PRK10519
550537022339	3 probable transmembrane helices predicted for SEN4274 by TMHMM2.0 at aa 20-42, 68-90 and 130-152
550537022340	HMMPfam hit to PF07670, Nucleoside recognition, score 1e-14
550537022341	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
550537022342	Nucleoside recognition; Region: Gate; pfam07670
550537022343	HMMPfam hit to PF07670, Nucleoside recognition, score 8e-15
550537022344	5 probable transmembrane helices predicted for SEN4275 by TMHMM2.0 at aa 37-59, 92-114, 146-165, 180-202 and 246-268
550537022345	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
550537022346	12 probable transmembrane helices predicted for SEN4276 by TMHMM2.0 at aa 13-35, 55-77, 84-103, 108-130, 137-159, 169-191, 212-234, 244-266, 271-293, 297-319, 331-353 and 358-380
550537022347	HMMPfam hit to PF06779, Protein of unknown function DUF1228, score 1.3e-49
550537022348	Predicted membrane protein [Function unknown]; Region: COG2733
550537022349	3 probable transmembrane helices predicted for SEN4277 by TMHMM2.0 at aa 13-32, 42-62 and 398-420
550537022350	HMMPfam hit to PF04286, Protein of unknown function DUF445, transmembrane, score 9.7e-153
550537022351	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
550537022352	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
550537022353	putative substrate translocation pore; other site
550537022354	12 probable transmembrane helices predicted for SEN4278 by TMHMM2.0 at aa 13-35, 50-72, 84-103, 107-129, 141-163, 167-189, 219-241, 256-278, 290-312, 316-338, 350-372 and 376-398
550537022355	HMMPfam hit to PF07690, Major facilitator superfamily MFS-1, score 5e-30
550537022356	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
550537022357	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022358	PS00216 Sugar transport proteins signature 1.
550537022359	hypothetical protein; Provisional; Region: PRK09956
550537022360	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
550537022361	HMMPfam hit to PF04754, Transposase (), YhgA-like, score 2.9e-197
550537022362	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
550537022363	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
550537022364	NAD(P) binding site [chemical binding]; other site
550537022365	catalytic residues [active]
550537022366	HMMPfam hit to PF00171, Aldehyde dehydrogenase, score 2.5e-147
550537022367	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537022368	PS00070 Aldehyde dehydrogenases cysteine active site.
550537022369	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
550537022370	HMMPfam hit to PF06568, Protein of unknown function DUF1127, score 2e-13
550537022371	Imigration control region; ROD40
550537022372	Protein of unknown function DUF91; Region: DUF91; cl00709
550537022373	Uncharacterized conserved protein [Function unknown]; Region: COG3586
550537022374	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
550537022375	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
550537022376	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
550537022377	ATP binding site [chemical binding]; other site
550537022378	putative Mg++ binding site [ion binding]; other site
550537022379	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
550537022380	HMMPfam hit to PF04851, Restriction endonuclease, type I, R subunit/Type III, Res subunit, score 2e-09
550537022381	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022382	HMMPfam hit to PF04313, Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N terminus, score 1.8e-58
550537022383	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
550537022384	HMMPfam hit to PF01420, Restriction endonuclease, type I, S subunit, EcoBI, score 1.5e-17
550537022385	HMMPfam hit to PF01420, Restriction endonuclease, type I, S subunit, EcoBI, score 8.6e-29
550537022386	HsdM N-terminal domain; Region: HsdM_N; pfam12161
550537022387	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
550537022388	Methyltransferase domain; Region: Methyltransf_26; pfam13659
550537022389	HMMPfam hit to PF02384, N-6 DNA methylase, score 2.9e-200
550537022390	PS00092 N-6 Adenine-specific DNA methylases signature.
550537022391	Associated with restriction systems in many genetic backgrounds including S. enteritidis. This CDS appears to have lost the N-terminus and suffered a frameshift mutation
550537022392	HMMPfam hit to PF04471, Restriction endonuclease, type IV-like, Mrr, score 0.00042
550537022393	Methyltransferase domain; Region: Methyltransf_26; pfam13659
550537022394	HMMPfam hit to PF02384, N-6 DNA methylase, score 7.5e-42
550537022395	PS00092 N-6 Adenine-specific DNA methylases signature.
550537022396	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
550537022397	HMMPfam hit to PF01420, Restriction endonuclease, type I, S subunit, EcoBI, score 1.1e-05
550537022398	Nuclease-related domain; Region: NERD; pfam08378
550537022399	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
550537022400	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
550537022401	Family description; Region: UvrD_C_2; pfam13538
550537022402	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022403	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
550537022404	HMMPfam hit to PF04365, Protein of unknown function DUF497, score 5.8e-20
550537022405	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
550537022406	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
550537022407	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
550537022408	P-loop, Walker A motif; other site
550537022409	Base recognition motif; other site
550537022410	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
550537022411	HMMPfam hit to PF07683, Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal, score 1.6e-34
550537022412	HMMPfam hit to PF02492, Cobalamin (vitamin B12) biosynthesis CobW-like, score 4.1e-76
550537022413	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022414	Uncharacterized small protein [Function unknown]; Region: COG2879
550537022415	HMMPfam hit to PF04328, Protein of unknown function DUF466, score 1.6e-46
550537022416	carbon starvation protein A; Provisional; Region: PRK15015
550537022417	Carbon starvation protein CstA; Region: CstA; pfam02554
550537022418	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
550537022419	16 probable transmembrane helices predicted for SEN4297 by TMHMM2.0 at aa 12-29, 34-56, 89-111, 121-140, 161-183, 193-215, 220-242, 257-279, 286-305, 325-347, 364-386, 486-505, 532-551, 566-588, 595-617 and 662-684
550537022420	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022421	HMMPfam hit to PF02554, Carbon starvation protein CstA, score 3.7e-287
550537022422	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022423	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022424	methyl-accepting protein IV; Provisional; Region: PRK09793
550537022425	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
550537022426	dimer interface [polypeptide binding]; other site
550537022427	ligand binding site [chemical binding]; other site
550537022428	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
550537022429	dimerization interface [polypeptide binding]; other site
550537022430	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
550537022431	dimer interface [polypeptide binding]; other site
550537022432	putative CheW interface [polypeptide binding]; other site
550537022433	2 probable transmembrane helices predicted for SEN4298 by TMHMM2.0 at aa 7-29 and 192-214
550537022434	HMMPfam hit to PF02203, Ligand binding Tar, score 1.2e-56
550537022435	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1.8e-16
550537022436	PS00538 Bacterial chemotaxis sensory transducers signature.
550537022437	HMMPfam hit to PF00015, Bacterial chemotaxis sensory transducer, score 4.6e-122
550537022438	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
550537022439	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537022440	Walker A motif; other site
550537022441	ATP binding site [chemical binding]; other site
550537022442	Walker B motif; other site
550537022443	arginine finger; other site
550537022444	Transcriptional antiterminator [Transcription]; Region: COG3933
550537022445	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
550537022446	active pocket/dimerization site; other site
550537022447	active site
550537022448	phosphorylation site [posttranslational modification]
550537022449	PRD domain; Region: PRD; pfam00874
550537022450	HMMPfam hit to PF00158, RNA polymerase sigma factor 54, interaction, score 6e-65
550537022451	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
550537022452	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022453	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
550537022454	PS00690 DEAH-box subfamily ATP-dependent helicases signature.
550537022455	HMMPfam hit to PF00874, PRD, score 7.5e-16
550537022456	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
550537022457	active pocket/dimerization site; other site
550537022458	active site
550537022459	phosphorylation site [posttranslational modification]
550537022460	HMMPfam hit to PF03610, Phosphotransferase system, fructose subfamily IIA component, score 8.6e-08
550537022461	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
550537022462	active site
550537022463	phosphorylation site [posttranslational modification]
550537022464	HMMPfam hit to PF03830, Phosphotransferase system, sorbose subfamily IIB component, score 1.6e-44
550537022465	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
550537022466	HMMPfam hit to PF03609, Phosphotransferase system, sorbose-specific IIC subunit, score 1.3e-53
550537022467	7 probable transmembrane helices predicted for SEN4302 by TMHMM2.0 at aa 7-29, 44-63, 70-92, 96-118, 138-160, 180-199 and 206-237
550537022468	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
550537022469	HMMPfam hit to PF03613, Phosphotransferase system, mannose/fructose/sorbose family IID component, score 7e-115
550537022470	6 probable transmembrane helices predicted for SEN4303 by TMHMM2.0 at aa 69-91, 111-133, 146-168, 197-219, 231-253 and 258-277
550537022471	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
550537022472	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
550537022473	dimer interface [polypeptide binding]; other site
550537022474	active site
550537022475	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
550537022476	dimer interface [polypeptide binding]; other site
550537022477	active site
550537022478	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 9.9e-10
550537022479	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022480	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 0.0064
550537022481	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
550537022482	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
550537022483	putative active site [active]
550537022484	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
550537022485	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 1.5e-11
550537022486	HMMPfam hit to PF01380, Sugar isomerase (SIS), score 0.013
550537022487	phosphoglycerol transferase I; Provisional; Region: PRK03776
550537022488	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
550537022489	HMMPfam hit to PF00884, Sulphatase, score 1.8e-20
550537022490	2 probable transmembrane helices predicted for SEN4306 by TMHMM2.0 at aa 43-65 and 77-99
550537022491	hypothetical protein; Provisional; Region: PRK11667
550537022492	1 probable transmembrane helix predicted for SEN4307 by TMHMM2.0 at aa 7-29
550537022493	DNA replication protein DnaC; Validated; Region: PRK07952
550537022494	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
550537022495	Walker A motif; other site
550537022496	ATP binding site [chemical binding]; other site
550537022497	Walker B motif; other site
550537022498	primosomal protein DnaI; Provisional; Region: PRK02854
550537022499	hypothetical protein; Provisional; Region: PRK09917
550537022500	4 probable transmembrane helices predicted for SEN4310 by TMHMM2.0 at aa 7-29, 53-75, 87-109 and 129-151
550537022501	Uncharacterized conserved protein [Function unknown]; Region: COG2966
550537022502	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
550537022503	4 probable transmembrane helices predicted for SEN4311 by TMHMM2.0 at aa 184-201, 214-236, 241-263 and 276-298
550537022504	HMMPfam hit to PF06738, Protein of unknown function DUF1212, score 9.3e-75
550537022505	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022506	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
550537022507	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537022508	DNA binding residues [nucleotide binding]
550537022509	dimerization interface [polypeptide binding]; other site
550537022510	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 1.3e-07
550537022511	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
550537022512	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
550537022513	DNA binding residues [nucleotide binding]
550537022514	HMMPfam hit to PF00196, Bacterial regulatory protein, LuxR, score 6.5e-15
550537022515	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
550537022516	putative deacylase active site [active]
550537022517	HMMPfam hit to PF04073, YbaK/prolyl-tRNA synthetase associated region, score 2.3e-44
550537022518	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
550537022519	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
550537022520	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
550537022521	HMMPfam hit to PF06276, Ferric iron reductase, score 6.5e-147
550537022522	PS00294 Prenyl group binding site (CAAX box).
550537022523	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
550537022524	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
550537022525	metal binding site [ion binding]; metal-binding site
550537022526	active site
550537022527	I-site; other site
550537022528	HMMPfam hit to PF00990, GGDEF, score 1.1e-62
550537022529	5 probable transmembrane helices predicted for SEN4316 by TMHMM2.0 at aa 21-40, 45-62, 69-86, 101-123 and 144-163
550537022530	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
550537022531	HMMPfam hit to PF07256, Protein of unknown function DUF1435, score 6.5e-54
550537022532	3 probable transmembrane helices predicted for SEN4317 by TMHMM2.0 at aa 5-27, 31-48 and 55-72
550537022533	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
550537022534	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
550537022535	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
550537022536	S-adenosylmethionine binding site [chemical binding]; other site
550537022537	HMMPfam hit to PF05175, Methyltransferase small, score 7.5e-100
550537022538	PS00092 N-6 Adenine-specific DNA methylases signature.
550537022539	HMMPfam hit to PF08468, Methyltransferase small, N-terminal, score 3.3e-94
550537022540	DNA polymerase III subunit psi; Validated; Region: PRK06856
550537022541	HMMPfam hit to PF03603, DNA polymerase III, psi subunit, score 1.4e-52
550537022542	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
550537022543	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
550537022544	Coenzyme A binding pocket [chemical binding]; other site
550537022545	HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 2.4e-22
550537022546	dUMP phosphatase; Provisional; Region: PRK09449
550537022547	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537022548	motif II; other site
550537022549	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 1.2e-30
550537022550	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
550537022551	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
550537022552	G1 box; other site
550537022553	putative GEF interaction site [polypeptide binding]; other site
550537022554	GTP/Mg2+ binding site [chemical binding]; other site
550537022555	Switch I region; other site
550537022556	G2 box; other site
550537022557	G3 box; other site
550537022558	Switch II region; other site
550537022559	G4 box; other site
550537022560	G5 box; other site
550537022561	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
550537022562	HMMPfam hit to PF00009, Protein synthesis factor, GTP-binding, score 6.2e-60
550537022563	PS00301 GTP-binding elongation factors signature.
550537022564	HMMPfam hit to PF03144, Translation elongation factor EFTu/EF1A, domain 2, score 9.6e-14
550537022565	periplasmic protein; Provisional; Region: PRK10568
550537022566	BON domain; Region: BON; pfam04972
550537022567	HMMPfam hit to PF04972, Transport-associated, score 1e-15
550537022568	HMMPfam hit to PF04972, Transport-associated, score 1.2e-14
550537022569	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
550537022570	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
550537022571	active site
550537022572	nucleophile elbow; other site
550537022573	HMMPfam hit to PF01734, Patatin, score 2.4e-26
550537022574	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
550537022575	active site
550537022576	HMMPfam hit to PF01026, Deoxyribonuclease, TatD-related, score 3.2e-100
550537022577	PS01137 Uncharacterized protein family UPF0006 signature 1.
550537022578	PS01090 Uncharacterized protein family UPF0006 signature 2.
550537022579	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
550537022580	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
550537022581	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
550537022582	FeS/SAM binding site; other site
550537022583	HMMPfam hit to PF04055, Radical SAM, score 1.1e-08
550537022584	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 0.0036
550537022585	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537022586	HMMPfam hit to PF00037, 4Fe-4S ferredoxin, iron-sulphur binding, score 4.5e-05
550537022587	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
550537022588	PS01087 Radical activating enzymes signature.
550537022589	PS00190 Cytochrome c family heme-binding site signature.
550537022590	hypothetical protein; Provisional; Region: PRK10977
550537022591	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
550537022592	intersubunit interface [polypeptide binding]; other site
550537022593	active site
550537022594	catalytic residue [active]
550537022595	HMMPfam hit to PF01791, Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase, score 1.7e-83
550537022596	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
550537022597	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
550537022598	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
550537022599	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
550537022600	HMMPfam hit to PF02885, Glycosyl transferase, family 3, score 4.3e-26
550537022601	HMMPfam hit to PF00591, Glycosyl transferase, family 3, score 5.4e-85
550537022602	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022603	PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature.
550537022604	HMMPfam hit to PF07831, Pyrimidine nucleoside phosphorylase, C-terminal, score 4.5e-31
550537022605	phosphopentomutase; Provisional; Region: PRK05362
550537022606	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
550537022607	HMMPfam hit to PF08342, Phosphopentomutase N-terminal, score 2e-68
550537022608	HMMPfam hit to PF01676, Metalloenzyme, score 5.4e-48
550537022609	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
550537022610	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
550537022611	HMMPfam hit to PF01048, Nucleoside phosphorylase, score 2.4e-115
550537022612	PS01232 Purine and other phosphorylases family 1 signature.
550537022613	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
550537022614	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09775
550537022615	HipA-like C-terminal domain; Region: HipA_C; pfam07804
550537022616	HMMPfam hit to PF07805, HipA-like, N-terminal, score 5.1e-11
550537022617	HMMPfam hit to PF07804, HipA-like, C-terminal, score 4e-05
550537022618	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
550537022619	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
550537022620	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
550537022621	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase, score 1.3e-18
550537022622	hypothetical protein; Provisional; Region: PRK11246
550537022623	2 probable transmembrane helices predicted for SEN4333 by TMHMM2.0 at aa 13-32 and 162-184
550537022624	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
550537022625	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
550537022626	motif II; other site
550537022627	HMMPfam hit to PF00702, Haloacid dehalogenase-like hydrolase, score 3.9e-26
550537022628	DNA repair protein RadA; Region: sms; TIGR00416
550537022629	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
550537022630	Walker A motif/ATP binding site; other site
550537022631	ATP binding site [chemical binding]; other site
550537022632	Walker B motif; other site
550537022633	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
550537022634	PS00190 Cytochrome c family heme-binding site signature.
550537022635	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022636	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
550537022637	non-specific DNA binding site [nucleotide binding]; other site
550537022638	salt bridge; other site
550537022639	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
550537022640	sequence-specific DNA binding site [nucleotide binding]; other site
550537022641	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
550537022642	active site
550537022643	(T/H)XGH motif; other site
550537022644	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
550537022645	HMMPfam hit to PF01381, Helix-turn-helix type 3, score 4.5e-10
550537022646	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022647	PS00687 Aldehyde dehydrogenases glutamic acid active site.
550537022648	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
550537022649	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537022650	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537022651	ABC transporter; Region: ABC_tran_2; pfam12848
550537022652	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
550537022653	HMMPfam hit to PF00005, ABC transporter related, score 7.7e-56
550537022654	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022655	HMMPfam hit to PF00005, ABC transporter related, score 1.8e-62
550537022656	PS00211 ABC transporters family signature.
550537022657	PS00017 ATP/GTP-binding site motif A (P-loop).
550537022658	lytic murein transglycosylase; Provisional; Region: PRK11619
550537022659	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
550537022660	N-acetyl-D-glucosamine binding site [chemical binding]; other site
550537022661	catalytic residue [active]
550537022662	HMMPfam hit to PF01464, Lytic transglycosylase-like, catalytic, score 1.6e-44
550537022663	PS00922 Prokaryotic transglycosylases signature.
550537022664	Trp operon repressor; Provisional; Region: PRK01381
550537022665	HMMPfam hit to PF01371, Trp repressor, score 3.7e-41
550537022666	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
550537022667	HMMPfam hit to PF01931, Protein of unknown function DUF84, score 3.9e-108
550537022668	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
550537022669	catalytic core [active]
550537022670	HMMPfam hit to PF00300, Phosphoglycerate mutase, score 7.1e-50
550537022671	PS00175 Phosphoglycerate mutase family phosphohistidine signature.
550537022672	1 probable transmembrane helix predicted for SEN4341 by TMHMM2.0 at aa 146-168
550537022673	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022674	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
550537022675	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
550537022676	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
550537022677	HMMPfam hit to PF06445, Bacterial transcription activator, effector binding, score 4.8e-23
550537022678	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 2.8e-09
550537022679	PS00041 Bacterial regulatory proteins, araC family signature.
550537022680	HMMPfam hit to PF00165, Helix-turn-helix, AraC type, score 4.5e-11
550537022681	hypothetical protein; Provisional; Region: PRK10756
550537022682	CreA protein; Region: CreA; pfam05981
550537022683	HMMPfam hit to PF05981, CreA, score 2.8e-95
550537022684	DNA-binding response regulator CreB; Provisional; Region: PRK11083
550537022685	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537022686	active site
550537022687	phosphorylation site [posttranslational modification]
550537022688	intermolecular recognition site; other site
550537022689	dimerization interface [polypeptide binding]; other site
550537022690	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537022691	DNA binding site [nucleotide binding]
550537022692	HMMPfam hit to PF00072, Response regulator receiver, score 3.2e-39
550537022693	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 1.6e-20
550537022694	sensory histidine kinase CreC; Provisional; Region: PRK11100
550537022695	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
550537022696	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
550537022697	dimer interface [polypeptide binding]; other site
550537022698	phosphorylation site [posttranslational modification]
550537022699	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
550537022700	ATP binding site [chemical binding]; other site
550537022701	Mg2+ binding site [ion binding]; other site
550537022702	G-X-G motif; other site
550537022703	HMMPfam hit to PF00672, Histidine kinase, HAMP region, score 1.8e-10
550537022704	1 probable transmembrane helix predicted for SEN4345 by TMHMM2.0 at aa 96-118
550537022705	HMMPfam hit to PF00512, Histidine kinase A, N-terminal, score 3.3e-15
550537022706	HMMPfam hit to PF02518, ATP-binding region, ATPase-like, score 1.4e-31
550537022707	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
550537022708	PS00430 TonB-dependent receptor proteins signature 1.
550537022709	HMMPfam hit to PF06123, Inner membrane CreD, score 4.8e-273
550537022710	6 probable transmembrane helices predicted for SEN4346 by TMHMM2.0 at aa 10-32, 298-317, 321-343, 350-372, 377-396 and 403-420
550537022711	putative major fimbrial protein SthE; Provisional; Region: PRK15292
550537022712	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
550537022713	fimbrial operon sth
550537022714	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 3.6e-05
550537022715	putative fimbrial protein SthD; Provisional; Region: PRK15293
550537022716	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 2.1e-11
550537022717	1 probable transmembrane helix predicted for SEN4348 by TMHMM2.0 at aa 7-29
550537022718	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
550537022719	PapC N-terminal domain; Region: PapC_N; pfam13954
550537022720	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
550537022721	PapC C-terminal domain; Region: PapC_C; pfam13953
550537022722	HMMPfam hit to PF00577, Fimbrial biogenesis outer membrane usher protein, score 0
550537022723	PS01151 Fimbrial biogenesis outer membrane usher protein signature.
550537022724	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
550537022725	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
550537022726	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
550537022727	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
550537022728	HMMPfam hit to PF02753, Bacterial pili assembly chaperone, score 1.5e-16
550537022729	HMMPfam hit to PF00345, Bacterial pili assembly chaperone, score 6.4e-43
550537022730	PS00635 Gram-negative pili assembly chaperone signature.
550537022731	putative fimbrial protein SthA; Provisional; Region: PRK15296
550537022732	HMMPfam hit to PF00419, Fimbrial protein, C-terminal, score 3.1e-20
550537022733	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
550537022734	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
550537022735	Helix-turn-helix domain; Region: HTH_36; pfam13730
550537022736	1 probable transmembrane helix predicted for SEN4353 by TMHMM2.0 at aa 7-29
550537022737	two-component response regulator; Provisional; Region: PRK11173
550537022738	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
550537022739	active site
550537022740	phosphorylation site [posttranslational modification]
550537022741	intermolecular recognition site; other site
550537022742	dimerization interface [polypeptide binding]; other site
550537022743	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
550537022744	DNA binding site [nucleotide binding]
550537022745	HMMPfam hit to PF00486, Transcriptional regulatory protein, C-terminal, score 3.6e-18
550537022746	HMMPfam hit to PF00072, Response regulator receiver, score 3.9e-38
550537022747	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
550537022748	putative RNA methyltransferase; Provisional; Region: PRK10433
550537022749	HMMPfam hit to PF00588, tRNA/rRNA methyltransferase, SpoU, score 4.2e-36