-- dump date   	20140620_041943
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
697329000001	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
697329000002	AAA domain; Region: AAA_30; pfam13604
697329000003	Family description; Region: UvrD_C_2; pfam13538
697329000004	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
697329000005	AAA domain; Region: AAA_30; pfam13604
697329000006	Family description; Region: UvrD_C_2; pfam13538
697329000007	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329000008	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
697329000009	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
697329000010	active site
697329000011	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
697329000012	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
697329000013	DNA polymerase III subunit alpha; Reviewed; Region: PRK07373
697329000014	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
697329000015	generic binding surface II; other site
697329000016	generic binding surface I; other site
697329000017	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
697329000018	generic binding surface II; other site
697329000019	generic binding surface I; other site
697329000020	AAA-like domain; Region: AAA_10; pfam12846
697329000021	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
697329000022	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329000023	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
697329000024	This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111
697329000025	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
697329000026	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
697329000027	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
697329000028	ATP binding site [chemical binding]; other site
697329000029	Walker A motif; other site
697329000030	hexamer interface [polypeptide binding]; other site
697329000031	Walker B motif; other site
697329000032	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
697329000033	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
697329000034	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
697329000035	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
697329000036	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
697329000037	TadE-like protein; Region: TadE; pfam07811
697329000038	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
697329000039	active site
697329000040	catalytic site [active]
697329000041	substrate binding site [chemical binding]; other site
697329000042	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329000043	non-specific DNA binding site [nucleotide binding]; other site
697329000044	sequence-specific DNA binding site [nucleotide binding]; other site
697329000045	salt bridge; other site
697329000046	Phage tail protein; Region: Sipho_tail; cl17486
697329000047	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
697329000048	Protein of unknown function (DUF1430); Region: DUF1430; pfam07242
697329000049	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329000050	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
697329000051	Walker A/P-loop; other site
697329000052	ATP binding site [chemical binding]; other site
697329000053	Q-loop/lid; other site
697329000054	ABC transporter signature motif; other site
697329000055	Walker B; other site
697329000056	D-loop; other site
697329000057	H-loop/switch region; other site
697329000058	putative transposase OrfB; Reviewed; Region: PHA02517
697329000059	HTH-like domain; Region: HTH_21; pfam13276
697329000060	Integrase core domain; Region: rve; pfam00665
697329000061	Integrase core domain; Region: rve_2; pfam13333
697329000062	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
697329000063	Transposase; Region: HTH_Tnp_1; cl17663
697329000064	Transposase; Region: HTH_Tnp_1; cl17663
697329000065	Helix-turn-helix domain; Region: HTH_28; pfam13518
697329000066	Winged helix-turn helix; Region: HTH_29; pfam13551
697329000067	MAEBL; Provisional; Region: PTZ00121
697329000068	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
697329000069	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
697329000070	active site
697329000071	catalytic site [active]
697329000072	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
697329000073	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
697329000074	DHH family; Region: DHH; pfam01368
697329000075	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329000076	Walker A/P-loop; other site
697329000077	ATP binding site [chemical binding]; other site
697329000078	Q-loop/lid; other site
697329000079	ABC transporter signature motif; other site
697329000080	CHAP domain; Region: CHAP; cl17642
697329000081	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329000082	putative sugar binding sites [chemical binding]; other site
697329000083	Q-X-W motif; other site
697329000084	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329000085	putative sugar binding sites [chemical binding]; other site
697329000086	Q-X-W motif; other site
697329000087	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
697329000088	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329000089	Interdomain contacts; other site
697329000090	Cytokine receptor motif; other site
697329000091	Domain of unknown function (DUF370); Region: DUF370; cl00898
697329000092	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000093	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000094	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000095	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
697329000096	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
697329000097	metal ion-dependent adhesion site (MIDAS); other site
697329000098	dsRNA-specific ribonuclease [Transcription]; Region: Rnc; COG0571
697329000099	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
697329000100	dimerization interface [polypeptide binding]; other site
697329000101	active site
697329000102	metal binding site [ion binding]; metal-binding site
697329000103	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
697329000104	dsRNA binding site [nucleotide binding]; other site
697329000105	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
697329000106	dsRNA binding site [nucleotide binding]; other site
697329000107	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
697329000108	TOPRIM_TopoIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IA family of DNA topoisomerases (TopoIA). This subgroup contains proteins similar to the Type I DNA topoisomerases: E. coli...; Region: TOPRIM_TopoIA; cd01028
697329000109	active site
697329000110	interdomain interaction site; other site
697329000111	putative metal-binding site [ion binding]; other site
697329000112	nucleotide binding site [chemical binding]; other site
697329000113	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
697329000114	domain I; other site
697329000115	DNA binding groove [nucleotide binding]
697329000116	phosphate binding site [ion binding]; other site
697329000117	domain II; other site
697329000118	domain III; other site
697329000119	nucleotide binding site [chemical binding]; other site
697329000120	catalytic site [active]
697329000121	domain IV; other site
697329000122	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
697329000123	active site
697329000124	Protein of unknown function (DUF4046); Region: DUF4046; pfam13255
697329000125	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000126	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
697329000127	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
697329000128	Transposase [DNA replication, recombination, and repair]; Region: COG5433
697329000129	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000130	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000131	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000132	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000133	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000134	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000135	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000136	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000137	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000138	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000139	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000140	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329000141	Interdomain contacts; other site
697329000142	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
697329000143	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
697329000144	sugar binding site [chemical binding]; other site
697329000145	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
697329000146	sugar binding site [chemical binding]; other site
697329000147	AAA domain; Region: AAA_14; pfam13173
697329000148	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
697329000149	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329000150	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329000151	non-specific DNA binding site [nucleotide binding]; other site
697329000152	salt bridge; other site
697329000153	sequence-specific DNA binding site [nucleotide binding]; other site
697329000154	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329000155	non-specific DNA binding site [nucleotide binding]; other site
697329000156	salt bridge; other site
697329000157	sequence-specific DNA binding site [nucleotide binding]; other site
697329000158	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000159	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
697329000160	Probable transposase; Region: OrfB_IS605; pfam01385
697329000161	Low molecular weight phosphatase family; Region: LMWPc; cl00105
697329000162	active site
697329000163	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000164	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_1; cd10446
697329000165	GIY-YIG motif/motif A; other site
697329000166	putative active site [active]
697329000167	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
697329000168	Bacterial SH3 domain; Region: SH3_3; cl17532
697329000169	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
697329000170	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000171	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000172	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000173	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000174	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000175	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000176	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000177	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000178	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000179	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000180	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000181	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000182	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000183	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000184	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000185	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000186	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000187	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000188	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000189	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000190	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000191	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000192	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000193	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329000194	Interdomain contacts; other site
697329000195	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329000196	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329000197	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329000198	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329000199	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329000200	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329000201	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329000202	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000203	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
697329000204	active site
697329000205	DNA binding site [nucleotide binding]
697329000206	Int/Topo IB signature motif; other site
697329000207	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329000208	AAA domain; Region: AAA_21; pfam13304
697329000209	Walker A/P-loop; other site
697329000210	ATP binding site [chemical binding]; other site
697329000211	AAA domain; Region: AAA_21; pfam13304
697329000212	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
697329000213	metal ion-dependent adhesion site (MIDAS); other site
697329000214	Putative amidase domain; Region: Amidase_6; pfam12671
697329000215	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329000216	non-specific DNA binding site [nucleotide binding]; other site
697329000217	salt bridge; other site
697329000218	sequence-specific DNA binding site [nucleotide binding]; other site
697329000219	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329000220	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329000221	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
697329000222	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
697329000223	CoA binding domain; Region: CoA_binding; pfam02629
697329000224	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
697329000225	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
697329000226	putative catalytic cysteine [active]
697329000227	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
697329000228	putative active site [active]
697329000229	metal binding site [ion binding]; metal-binding site
697329000230	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
697329000231	active site
697329000232	ATP binding site [chemical binding]; other site
697329000233	Phosphotransferase enzyme family; Region: APH; pfam01636
697329000234	substrate binding site [chemical binding]; other site
697329000235	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
697329000236	dimer interface [polypeptide binding]; other site
697329000237	[2Fe-2S] cluster binding site [ion binding]; other site
697329000238	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
697329000239	dimer interface [polypeptide binding]; other site
697329000240	[2Fe-2S] cluster binding site [ion binding]; other site
697329000241	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
697329000242	4Fe-4S binding domain; Region: Fer4; pfam00037
697329000243	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
697329000244	Putative Fe-S cluster; Region: FeS; cl17515
697329000245	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
697329000246	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
697329000247	4Fe-4S binding domain; Region: Fer4_6; pfam12837
697329000248	4Fe-4S binding domain; Region: Fer4; pfam00037
697329000249	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
697329000250	AAA domain; Region: AAA_14; pfam13173
697329000251	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
697329000252	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
697329000253	DNA polymerase IV; Reviewed; Region: PRK03103
697329000254	Y-family of DNA polymerases; Region: PolY; cl12025
697329000255	active site
697329000256	DNA binding site [nucleotide binding]
697329000257	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
697329000258	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
697329000259	Family description; Region: ACT_7; pfam13840
697329000260	A nuclease of the HNH/ENDO VII superfamily with conserved LHH; Region: LHH; pfam14411
697329000261	LEM-like domain of lamina-associated polypeptide 2 (LAP2) and similar proteins; Region: LEM_like; cl06998
697329000262	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
697329000263	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329000264	Walker A motif; other site
697329000265	ATP binding site [chemical binding]; other site
697329000266	Walker B motif; other site
697329000267	arginine finger; other site
697329000268	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000269	active site
697329000270	DNA binding site [nucleotide binding]
697329000271	Int/Topo IB signature motif; other site
697329000272	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329000273	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000274	active site
697329000275	DNA binding site [nucleotide binding]
697329000276	Int/Topo IB signature motif; other site
697329000277	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
697329000278	Prokaryotic E2 family B; Region: Prok-E2_B; pfam14461
697329000279	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cl17196
697329000280	ATP binding site [chemical binding]; other site
697329000281	substrate interface [chemical binding]; other site
697329000282	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
697329000283	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
697329000284	active site
697329000285	ATP binding site [chemical binding]; other site
697329000286	substrate binding site [chemical binding]; other site
697329000287	activation loop (A-loop); other site
697329000288	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
697329000289	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
697329000290	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329000291	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
697329000292	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
697329000293	AAA domain; Region: AAA_14; pfam13173
697329000294	Predicted transcriptional regulator [Transcription]; Region: COG2932
697329000295	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329000296	non-specific DNA binding site [nucleotide binding]; other site
697329000297	salt bridge; other site
697329000298	sequence-specific DNA binding site [nucleotide binding]; other site
697329000299	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
697329000300	Catalytic site [active]
697329000301	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
697329000302	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
697329000303	P-loop; other site
697329000304	Magnesium ion binding site [ion binding]; other site
697329000305	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
697329000306	Magnesium ion binding site [ion binding]; other site
697329000307	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
697329000308	ParB-like nuclease domain; Region: ParB; smart00470
697329000309	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
697329000310	DNA-binding interface [nucleotide binding]; DNA binding site
697329000311	Transposon-encoded protein TnpV; Region: TnpV; pfam14198
697329000312	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
697329000313	DNA binding site [nucleotide binding]
697329000314	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329000315	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329000316	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
697329000317	Walker A/P-loop; other site
697329000318	ATP binding site [chemical binding]; other site
697329000319	Q-loop/lid; other site
697329000320	ABC transporter signature motif; other site
697329000321	Walker B; other site
697329000322	D-loop; other site
697329000323	H-loop/switch region; other site
697329000324	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
697329000325	transmembrane helices; other site
697329000326	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
697329000327	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000328	Restriction endonuclease; Region: Mrr_cat; pfam04471
697329000329	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329000330	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329000331	catalytic residues [active]
697329000332	catalytic nucleophile [active]
697329000333	Recombinase; Region: Recombinase; pfam07508
697329000334	Domain of unknown function DUF87; Region: DUF87; pfam01935
697329000335	AAA-like domain; Region: AAA_10; pfam12846
697329000336	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
697329000337	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
697329000338	generic binding surface I; other site
697329000339	generic binding surface II; other site
697329000340	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329000341	Zn2+ binding site [ion binding]; other site
697329000342	Mg2+ binding site [ion binding]; other site
697329000343	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329000344	Walker A/P-loop; other site
697329000345	ATP binding site [chemical binding]; other site
697329000346	Q-loop/lid; other site
697329000347	ABC transporter signature motif; other site
697329000348	Walker B; other site
697329000349	D-loop; other site
697329000350	H-loop/switch region; other site
697329000351	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
697329000352	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
697329000353	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
697329000354	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
697329000355	HipA N-terminal domain; Region: Couple_hipA; pfam13657
697329000356	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
697329000357	HipA-like N-terminal domain; Region: HipA_N; pfam07805
697329000358	HipA-like C-terminal domain; Region: HipA_C; pfam07804
697329000359	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329000360	non-specific DNA binding site [nucleotide binding]; other site
697329000361	salt bridge; other site
697329000362	sequence-specific DNA binding site [nucleotide binding]; other site
697329000363	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
697329000364	AAA domain; Region: AAA_14; pfam13173
697329000365	Competence protein CoiA-like family; Region: CoiA; cl11541
697329000366	LabA_like proteins; Region: LabA_like; cd06167
697329000367	putative metal binding site [ion binding]; other site
697329000368	Cna protein B-type domain; Region: Cna_B; pfam05738
697329000369	Cna protein B-type domain; Region: Cna_B; pfam05738
697329000370	Cna protein B-type domain; Region: Cna_B; pfam05738
697329000371	Cna protein B-type domain; Region: Cna_B; pfam05738
697329000372	Cna protein B-type domain; Region: Cna_B; pfam05738
697329000373	DHH family; Region: DHH; pfam01368
697329000374	DHHA1 domain; Region: DHHA1; pfam02272
697329000375	Initiator Replication protein; Region: Rep_3; pfam01051
697329000376	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit [DNA replication, recombination, and repair]; Region: GyrB; COG0187
697329000377	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
697329000378	Mg2+ binding site [ion binding]; other site
697329000379	G-X-G motif; other site
697329000380	DNA gyrase B; Region: DNA_gyraseB; pfam00204
697329000381	ATP binding site [chemical binding]; other site
697329000382	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
697329000383	active site
697329000384	putative metal-binding site [ion binding]; other site
697329000385	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
697329000386	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329000387	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329000388	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329000389	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
697329000390	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000391	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
697329000392	Probable transposase; Region: OrfB_IS605; pfam01385
697329000393	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
697329000394	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
697329000395	CAP-like domain; other site
697329000396	active site
697329000397	primary dimer interface [polypeptide binding]; other site
697329000398	Restriction alleviation protein Lar; Region: Lar_restr_allev; cl08047
697329000399	ORF6C domain; Region: ORF6C; pfam10552
697329000400	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000401	Domain of unknown function (DUF4070); Region: DUF4070; pfam13282
697329000402	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329000403	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
697329000404	catalytic residues [active]
697329000405	catalytic nucleophile [active]
697329000406	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
697329000407	Beta-lactamase; Region: Beta-lactamase; pfam00144
697329000408	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
697329000409	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329000410	active site
697329000411	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329000412	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329000413	EF-hand domain pair; Region: EF_hand_5; pfam13499
697329000414	plasmid segregation protein ParM; Provisional; Region: PRK13917
697329000415	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
697329000416	Mg binding site [ion binding]; other site
697329000417	nucleotide binding site [chemical binding]; other site
697329000418	putative protofilament interface [polypeptide binding]; other site
697329000419	Domain of unknown function (DUF4317); Region: DUF4317; pfam14199
697329000420	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329000421	Double zinc ribbon; Region: DZR; pfam12773
697329000422	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000423	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
697329000424	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
697329000425	IHF dimer interface [polypeptide binding]; other site
697329000426	IHF - DNA interface [nucleotide binding]; other site
697329000427	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
697329000428	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329000429	Walker A/P-loop; other site
697329000430	ATP binding site [chemical binding]; other site
697329000431	Q-loop/lid; other site
697329000432	ABC transporter signature motif; other site
697329000433	Walker B; other site
697329000434	D-loop; other site
697329000435	H-loop/switch region; other site
697329000436	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
697329000437	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
697329000438	DNA methylase; Region: N6_N4_Mtase; pfam01555
697329000439	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
697329000440	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329000441	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329000442	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000443	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000444	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000445	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329000446	Probable transposase; Region: OrfB_IS605; pfam01385
697329000447	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
697329000448	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
697329000449	Protein of unknown function (DUF4241); Region: DUF4241; pfam14025
697329000450	Macro domain, Poa1p_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Poa1p_like; cd02901
697329000451	ADP-ribose binding site [chemical binding]; other site
697329000452	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000453	putative fimbrial outer membrane usher protein SteB; Provisional; Region: PRK15273
697329000454	Transposase IS200 like; Region: Y1_Tnp; pfam01797
697329000455	EF-hand domain pair; Region: EF_hand_5; pfam13499
697329000456	Stage V sporulation protein S (SpoVS); Region: SpoVS; cl01005
697329000457	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
697329000458	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
697329000459	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
697329000460	putative trimer interface [polypeptide binding]; other site
697329000461	putative CoA binding site [chemical binding]; other site
697329000462	Bacterial sugar transferase; Region: Bac_transf; pfam02397
697329000463	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329000464	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
697329000465	NAD(P) binding site [chemical binding]; other site
697329000466	active site
697329000467	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
697329000468	putative glycosyl transferase; Provisional; Region: PRK10307
697329000469	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
697329000470	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
697329000471	NAD(P) binding site [chemical binding]; other site
697329000472	homodimer interface [polypeptide binding]; other site
697329000473	substrate binding site [chemical binding]; other site
697329000474	active site
697329000475	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
697329000476	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
697329000477	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329000478	NAD(P) binding site [chemical binding]; other site
697329000479	active site
697329000480	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
697329000481	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
697329000482	active site
697329000483	homodimer interface [polypeptide binding]; other site
697329000484	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
697329000485	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
697329000486	LicD family; Region: LicD; cl01378
697329000487	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
697329000488	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329000489	catalytic residue [active]
697329000490	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329000491	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
697329000492	active site
697329000493	nucleotide binding site [chemical binding]; other site
697329000494	HIGH motif; other site
697329000495	KMSKS motif; other site
697329000496	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
697329000497	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
697329000498	LicD family; Region: LicD; pfam04991
697329000499	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329000500	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
697329000501	LicD family; Region: LicD; cl01378
697329000502	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
697329000503	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
697329000504	active site
697329000505	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
697329000506	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
697329000507	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
697329000508	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
697329000509	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
697329000510	dimer interface [polypeptide binding]; other site
697329000511	tetramer interface [polypeptide binding]; other site
697329000512	PYR/PP interface [polypeptide binding]; other site
697329000513	TPP binding site [chemical binding]; other site
697329000514	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
697329000515	TPP-binding site [chemical binding]; other site
697329000516	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329000517	NAD(P) binding site [chemical binding]; other site
697329000518	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
697329000519	active site
697329000520	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
697329000521	Acyltransferase family; Region: Acyl_transf_3; pfam01757
697329000522	Putative glucose-1-phosphate thymidylyltransferase, C-terminal Left-handed parallel beta-Helix (LbH) domain: Proteins in this family show simlarity to glucose-1-phosphate adenylyltransferases in that they contain N-terminal catalytic domains that...; Region: LbH_G1P_TT_C_like; cd05636
697329000523	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
697329000524	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329000525	ATP binding site [chemical binding]; other site
697329000526	putative Mg++ binding site [ion binding]; other site
697329000527	nucleotide binding region [chemical binding]; other site
697329000528	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
697329000529	ATP-binding site [chemical binding]; other site
697329000530	Helicase associated domain; Region: HA; pfam03457
697329000531	Helicase associated domain; Region: HA; pfam03457
697329000532	Helicase associated domain; Region: HA; pfam03457
697329000533	Helicase associated domain; Region: HA; pfam03457
697329000534	Helicase associated domain; Region: HA; pfam03457
697329000535	Helicase associated domain; Region: HA; pfam03457
697329000536	Helicase associated domain; Region: HA; pfam03457
697329000537	Helicase associated domain; Region: HA; pfam03457
697329000538	Helicase associated domain; Region: HA; pfam03457
697329000539	Helicase associated domain; Region: HA; pfam03457
697329000540	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329000541	ATP binding site [chemical binding]; other site
697329000542	putative Mg++ binding site [ion binding]; other site
697329000543	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329000544	nucleotide binding region [chemical binding]; other site
697329000545	ATP-binding site [chemical binding]; other site
697329000546	Helicase associated domain; Region: HA; pfam03457
697329000547	Helicase associated domain; Region: HA; pfam03457
697329000548	Helicase associated domain; Region: HA; pfam03457
697329000549	Helicase associated domain; Region: HA; pfam03457
697329000550	Helicase associated domain; Region: HA; pfam03457
697329000551	Helicase associated domain; Region: HA; pfam03457
697329000552	Helicase associated domain; Region: HA; pfam03457
697329000553	Helicase associated domain; Region: HA; pfam03457
697329000554	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
697329000555	RelB antitoxin; Region: RelB; cl01171
697329000556	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cl01497
697329000557	Immunoglobulin I-set domain; Region: I-set; pfam07679
697329000558	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
697329000559	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
697329000560	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
697329000561	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329000562	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
697329000563	catalytic residues [active]
697329000564	catalytic nucleophile [active]
697329000565	Presynaptic Site I dimer interface [polypeptide binding]; other site
697329000566	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
697329000567	Synaptic Flat tetramer interface [polypeptide binding]; other site
697329000568	Synaptic Site I dimer interface [polypeptide binding]; other site
697329000569	DNA binding site [nucleotide binding]
697329000570	Recombinase; Region: Recombinase; pfam07508
697329000571	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329000572	Transposase IS200 like; Region: Y1_Tnp; pfam01797
697329000573	Domain of unknown function (DUF1848); Region: DUF1848; pfam08902
697329000574	Winged helix-turn helix; Region: HTH_29; pfam13551
697329000575	Helix-turn-helix domain; Region: HTH_28; pfam13518
697329000576	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
697329000577	Integrase core domain; Region: rve; pfam00665
697329000578	Integrase core domain; Region: rve_3; cl15866
697329000579	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
697329000580	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
697329000581	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
697329000582	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329000583	Walker A motif; other site
697329000584	ATP binding site [chemical binding]; other site
697329000585	Walker B motif; other site
697329000586	arginine finger; other site
697329000587	Sulfatase; Region: Sulfatase; cl17466
697329000588	Ubiquitin; Region: Ubiquitin; cd01803
697329000589	Ubiquitin homologues; Region: UBQ; smart00213
697329000590	Ubq - E2 interaction site; other site
697329000591	Ubq - UCH interaction site; other site
697329000592	Ubq - CUE interaction site; other site
697329000593	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
697329000594	active site
697329000595	catalytic site [active]
697329000596	YodL-like; Region: YodL; pfam14191
697329000597	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
697329000598	DNA methylase; Region: N6_N4_Mtase; pfam01555
697329000599	DNA primase, catalytic core; Region: dnaG; TIGR01391
697329000600	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329000601	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
697329000602	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
697329000603	active site
697329000604	metal binding site [ion binding]; metal-binding site
697329000605	interdomain interaction site; other site
697329000606	PemK-like protein; Region: PemK; pfam02452
697329000607	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329000608	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
697329000609	Probable transposase; Region: OrfB_IS605; pfam01385
697329000610	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
697329000611	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
697329000612	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
697329000613	dimer interface [polypeptide binding]; other site
697329000614	ssDNA binding site [nucleotide binding]; other site
697329000615	tetramer (dimer of dimers) interface [polypeptide binding]; other site
697329000616	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
697329000617	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
697329000618	WYL domain; Region: WYL; pfam13280
697329000619	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000620	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000621	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cd00719
697329000622	GIY-YIG motif/motif A; other site
697329000623	active site
697329000624	catalytic site [active]
697329000625	metal binding site [ion binding]; metal-binding site
697329000626	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
697329000627	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
697329000628	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
697329000629	Transposase; Region: HTH_Tnp_1; cl17663
697329000630	Transposase; Region: HTH_Tnp_1; cl17663
697329000631	Helix-turn-helix domain; Region: HTH_28; pfam13518
697329000632	Winged helix-turn helix; Region: HTH_29; pfam13551
697329000633	putative transposase OrfB; Reviewed; Region: PHA02517
697329000634	HTH-like domain; Region: HTH_21; pfam13276
697329000635	Integrase core domain; Region: rve; pfam00665
697329000636	Integrase core domain; Region: rve_2; pfam13333
697329000637	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329000638	RNA polymerase sigma factor, FliA/WhiG family; Region: FliA_WhiG; TIGR02479
697329000639	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329000640	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329000641	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
697329000642	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329000643	active site
697329000644	HIGH motif; other site
697329000645	nucleotide binding site [chemical binding]; other site
697329000646	active site
697329000647	KMSKS motif; other site
697329000648	Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: MetG; COG0143
697329000649	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329000650	active site
697329000651	HIGH motif; other site
697329000652	nucleotide binding site [chemical binding]; other site
697329000653	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329000654	KMSKS motif; other site
697329000655	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
697329000656	anticodon binding site; other site
697329000657	tRNA binding surface [nucleotide binding]; other site
697329000658	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
697329000659	SdpI/YhfL protein family; Region: SdpI; pfam13630
697329000660	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
697329000661	dimerization interface [polypeptide binding]; other site
697329000662	putative DNA binding site [nucleotide binding]; other site
697329000663	putative Zn2+ binding site [ion binding]; other site
697329000664	Putative membrane peptidase family (DUF2324); Region: DUF2324; pfam10086
697329000665	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
697329000666	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
697329000667	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
697329000668	BioY family; Region: BioY; pfam02632
697329000669	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
697329000670	substrate binding site [chemical binding]; other site
697329000671	activation loop (A-loop); other site
697329000672	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
697329000673	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
697329000674	MgtE intracellular N domain; Region: MgtE_N; pfam03448
697329000675	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
697329000676	Divalent cation transporter; Region: MgtE; pfam01769
697329000677	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329000678	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329000679	DNA binding residues [nucleotide binding]
697329000680	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329000681	Coenzyme A binding pocket [chemical binding]; other site
697329000682	Dockerin type I repeat; Region: Dockerin_1; pfam00404
697329000683	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
697329000684	TrkA-N domain; Region: TrkA_N; pfam02254
697329000685	TrkA-C domain; Region: TrkA_C; pfam02080
697329000686	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
697329000687	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
697329000688	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
697329000689	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
697329000690	Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the...; Region: P_permease; cd01116
697329000691	transmembrane helices; other site
697329000692	Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]; Region: COG3437
697329000693	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329000694	active site
697329000695	phosphorylation site [posttranslational modification]
697329000696	intermolecular recognition site; other site
697329000697	dimerization interface [polypeptide binding]; other site
697329000698	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329000699	Zn2+ binding site [ion binding]; other site
697329000700	Mg2+ binding site [ion binding]; other site
697329000701	FOG: HPt domain [Signal transduction mechanisms]; Region: ArcB; COG2198
697329000702	Response regulator receiver domain; Region: Response_reg; pfam00072
697329000703	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329000704	active site
697329000705	phosphorylation site [posttranslational modification]
697329000706	intermolecular recognition site; other site
697329000707	dimerization interface [polypeptide binding]; other site
697329000708	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329000709	active site
697329000710	3-isopropylmalate dehydratase small subunit; Reviewed; Region: leuD; PRK00439
697329000711	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
697329000712	substrate binding site [chemical binding]; other site
697329000713	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
697329000714	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
697329000715	substrate binding site [chemical binding]; other site
697329000716	ligand binding site [chemical binding]; other site
697329000717	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
697329000718	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
697329000719	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
697329000720	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
697329000721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
697329000722	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
697329000723	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
697329000724	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
697329000725	active site
697329000726	(T/H)XGH motif; other site
697329000727	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
697329000728	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329000729	S-adenosylmethionine binding site [chemical binding]; other site
697329000730	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
697329000731	classical (c) SDRs; Region: SDR_c; cd05233
697329000732	NAD(P) binding site [chemical binding]; other site
697329000733	active site
697329000734	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
697329000735	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
697329000736	putative metal binding site [ion binding]; other site
697329000737	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
697329000738	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329000739	NAD(P) binding site [chemical binding]; other site
697329000740	active site
697329000741	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
697329000742	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
697329000743	metal-binding site [ion binding]
697329000744	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
697329000745	Soluble P-type ATPase [General function prediction only]; Region: COG4087
697329000746	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
697329000747	metal-binding site [ion binding]
697329000748	C-terminal domain of Faecalibacterium prausnitzii A2-165 FrmR , and related domains; this domain family was previously known as part of DUF156; Region: FpFrmR-Cterm-like_DUF156; cd10156
697329000749	putative homodimer interface [polypeptide binding]; other site
697329000750	putative homotetramer interface [polypeptide binding]; other site
697329000751	putative allosteric switch controlling residues; other site
697329000752	putative metal binding site [ion binding]; other site
697329000753	putative homodimer-homodimer interface [polypeptide binding]; other site
697329000754	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
697329000755	Part of AAA domain; Region: AAA_19; pfam13245
697329000756	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
697329000757	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
697329000758	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
697329000759	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
697329000760	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
697329000761	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
697329000762	substrate binding pocket [chemical binding]; other site
697329000763	dimer interface [polypeptide binding]; other site
697329000764	inhibitor binding site; inhibition site
697329000765	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
697329000766	methyltransferase cognate corrinoid proteins, Methanosarcina family; Region: pyl_corrinoid; TIGR02370
697329000767	B12 binding site [chemical binding]; other site
697329000768	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
697329000769	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329000770	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329000771	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329000772	DNA binding residues [nucleotide binding]
697329000773	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
697329000774	Prismane/CO dehydrogenase family; Region: Prismane; pfam03063
697329000775	ACS interaction site; other site
697329000776	CODH interaction site; other site
697329000777	metal cluster binding site [ion binding]; other site
697329000778	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
697329000779	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
697329000780	Walker A/P-loop; other site
697329000781	ATP binding site [chemical binding]; other site
697329000782	Q-loop/lid; other site
697329000783	ABC transporter signature motif; other site
697329000784	Walker B; other site
697329000785	D-loop; other site
697329000786	H-loop/switch region; other site
697329000787	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
697329000788	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
697329000789	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
697329000790	NMT1-like family; Region: NMT1_2; pfam13379
697329000791	substrate binding pocket [chemical binding]; other site
697329000792	membrane-bound complex binding site; other site
697329000793	hinge residues; other site
697329000794	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329000795	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000796	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000797	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000798	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000799	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000800	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329000801	Fibronectin type 3 domain; Region: FN3; smart00060
697329000802	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
697329000803	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
697329000804	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329000805	Walker A motif; other site
697329000806	ATP binding site [chemical binding]; other site
697329000807	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
697329000808	Walker B motif; other site
697329000809	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
697329000810	Clp protease; Region: CLP_protease; pfam00574
697329000811	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
697329000812	oligomer interface [polypeptide binding]; other site
697329000813	active site residues [active]
697329000814	trigger factor; Provisional; Region: tig; PRK01490
697329000815	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
697329000816	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
697329000817	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
697329000818	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329000819	active site
697329000820	metal binding site [ion binding]; metal-binding site
697329000821	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
697329000822	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
697329000823	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329000824	catalytic residue [active]
697329000825	hypothetical protein; Reviewed; Region: PRK12497
697329000826	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
697329000827	RNA/DNA hybrid binding site [nucleotide binding]; other site
697329000828	active site
697329000829	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
697329000830	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
697329000831	GTP/Mg2+ binding site [chemical binding]; other site
697329000832	G4 box; other site
697329000833	G5 box; other site
697329000834	G1 box; other site
697329000835	Switch I region; other site
697329000836	G2 box; other site
697329000837	G3 box; other site
697329000838	Switch II region; other site
697329000839	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
697329000840	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
697329000841	Catalytic site [active]
697329000842	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
697329000843	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
697329000844	Catalytic site [active]
697329000845	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
697329000846	radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936
697329000847	Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; pfam10105
697329000848	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
697329000849	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329000850	FeS/SAM binding site; other site
697329000851	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
697329000852	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329000853	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
697329000854	Protein of unknown function (DUF1667); Region: DUF1667; cl17602
697329000855	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
697329000856	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
697329000857	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
697329000858	Predicted dehydrogenase [General function prediction only]; Region: COG0579
697329000859	hydroxyglutarate oxidase; Provisional; Region: PRK11728
697329000860	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
697329000861	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
697329000862	metal binding site 2 [ion binding]; metal-binding site
697329000863	putative DNA binding helix; other site
697329000864	metal binding site 1 [ion binding]; metal-binding site
697329000865	dimer interface [polypeptide binding]; other site
697329000866	structural Zn2+ binding site [ion binding]; other site
697329000867	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
697329000868	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
697329000869	intersubunit interface [polypeptide binding]; other site
697329000870	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
697329000871	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
697329000872	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
697329000873	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
697329000874	ABC-ATPase subunit  interface; other site
697329000875	dimer interface [polypeptide binding]; other site
697329000876	putative PBP binding regions; other site
697329000877	Putative cyclase; Region: Cyclase; cl00814
697329000878	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000879	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329000880	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
697329000881	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
697329000882	synthetase active site [active]
697329000883	NTP binding site [chemical binding]; other site
697329000884	metal binding site [ion binding]; metal-binding site
697329000885	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
697329000886	Serine hydrolase; Region: Ser_hydrolase; cl17834
697329000887	HeH/LEM domain; Region: HeH; pfam12949
697329000888	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
697329000889	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329000890	Walker A motif; other site
697329000891	ATP binding site [chemical binding]; other site
697329000892	Walker B motif; other site
697329000893	arginine finger; other site
697329000894	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
697329000895	Integrase core domain; Region: rve; pfam00665
697329000896	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; cl04011
697329000897	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329000898	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329000899	catalytic residues [active]
697329000900	catalytic nucleophile [active]
697329000901	Recombinase; Region: Recombinase; pfam07508
697329000902	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329000903	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329000904	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
697329000905	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
697329000906	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
697329000907	putative FMN binding site [chemical binding]; other site
697329000908	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
697329000909	active site 1 [active]
697329000910	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
697329000911	active site 2 [active]
697329000912	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; pfam10020
697329000913	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
697329000914	active site
697329000915	catalytic site [active]
697329000916	substrate binding site [chemical binding]; other site
697329000917	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
697329000918	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329000919	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000920	active site
697329000921	DNA binding site [nucleotide binding]
697329000922	Int/Topo IB signature motif; other site
697329000923	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000924	active site
697329000925	DNA binding site [nucleotide binding]
697329000926	Int/Topo IB signature motif; other site
697329000927	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
697329000928	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000929	active site
697329000930	DNA binding site [nucleotide binding]
697329000931	Int/Topo IB signature motif; other site
697329000932	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329000933	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329000934	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329000935	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
697329000936	HeH/LEM domain; Region: HeH; pfam12949
697329000937	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
697329000938	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329000939	Walker A motif; other site
697329000940	ATP binding site [chemical binding]; other site
697329000941	Walker B motif; other site
697329000942	arginine finger; other site
697329000943	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329000944	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329000945	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
697329000946	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329000947	Walker A motif; other site
697329000948	ATP binding site [chemical binding]; other site
697329000949	Walker B motif; other site
697329000950	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
697329000951	Transposase; Region: HTH_Tnp_1; cl17663
697329000952	Transposase; Region: HTH_Tnp_1; cl17663
697329000953	Helix-turn-helix domain; Region: HTH_28; pfam13518
697329000954	Winged helix-turn helix; Region: HTH_29; pfam13551
697329000955	putative transposase OrfB; Reviewed; Region: PHA02517
697329000956	HTH-like domain; Region: HTH_21; pfam13276
697329000957	Integrase core domain; Region: rve; pfam00665
697329000958	Integrase core domain; Region: rve_2; pfam13333
697329000959	LabA_like proteins; Region: LabA_like; cd06167
697329000960	putative metal binding site [ion binding]; other site
697329000961	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329000962	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
697329000963	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329000964	Bacterial DNA-binding protein; Region: Bac_DNA_binding; pfam00216
697329000965	IHF dimer interface [polypeptide binding]; other site
697329000966	IHF - DNA interface [nucleotide binding]; other site
697329000967	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329000968	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329000969	catalytic residues [active]
697329000970	catalytic nucleophile [active]
697329000971	Recombinase; Region: Recombinase; pfam07508
697329000972	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329000973	Recombinase; Region: Recombinase; pfam07508
697329000974	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329000975	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329000976	catalytic residues [active]
697329000977	catalytic nucleophile [active]
697329000978	Recombinase; Region: Recombinase; pfam07508
697329000979	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329000980	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
697329000981	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329000982	Int/Topo IB signature motif; other site
697329000983	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000984	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
697329000985	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329000986	active site
697329000987	DNA binding site [nucleotide binding]
697329000988	Int/Topo IB signature motif; other site
697329000989	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
697329000990	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329000991	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329000992	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329000993	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329000994	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329000995	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329000996	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329000997	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
697329000998	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329000999	Walker A motif; other site
697329001000	ATP binding site [chemical binding]; other site
697329001001	Walker B motif; other site
697329001002	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
697329001003	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329001004	active site
697329001005	DNA binding site [nucleotide binding]
697329001006	Int/Topo IB signature motif; other site
697329001007	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329001008	active site
697329001009	DNA binding site [nucleotide binding]
697329001010	Int/Topo IB signature motif; other site
697329001011	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329001012	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329001013	non-specific DNA binding site [nucleotide binding]; other site
697329001014	salt bridge; other site
697329001015	sequence-specific DNA binding site [nucleotide binding]; other site
697329001016	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
697329001017	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329001018	motif II; other site
697329001019	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
697329001020	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
697329001021	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
697329001022	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
697329001023	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
697329001024	4Fe-4S binding domain; Region: Fer4; cl02805
697329001025	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Region: FrhB_FdhB_N; pfam04422
697329001026	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; Region: FrhB_FdhB_C; pfam04432
697329001027	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
697329001028	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
697329001029	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
697329001030	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
697329001031	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
697329001032	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
697329001033	substrate binding site; other site
697329001034	tetramer interface; other site
697329001035	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
697329001036	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
697329001037	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
697329001038	NADP binding site [chemical binding]; other site
697329001039	active site
697329001040	putative substrate binding site [chemical binding]; other site
697329001041	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
697329001042	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
697329001043	NAD binding site [chemical binding]; other site
697329001044	substrate binding site [chemical binding]; other site
697329001045	homodimer interface [polypeptide binding]; other site
697329001046	active site
697329001047	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
697329001048	putative ligand binding site [chemical binding]; other site
697329001049	putative catalytic site [active]
697329001050	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
697329001051	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
697329001052	active site
697329001053	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
697329001054	trimer interface [polypeptide binding]; other site
697329001055	active site
697329001056	substrate binding site [chemical binding]; other site
697329001057	CoA binding site [chemical binding]; other site
697329001058	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329001059	active site
697329001060	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
697329001061	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
697329001062	Bacterial sugar transferase; Region: Bac_transf; pfam02397
697329001063	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329001064	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
697329001065	NAD(P) binding site [chemical binding]; other site
697329001066	active site
697329001067	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
697329001068	Bacterial sugar transferase; Region: Bac_transf; cl00939
697329001069	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
697329001070	putative trimer interface [polypeptide binding]; other site
697329001071	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329001072	ATP binding site [chemical binding]; other site
697329001073	putative Mg++ binding site [ion binding]; other site
697329001074	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329001075	nucleotide binding region [chemical binding]; other site
697329001076	ATP-binding site [chemical binding]; other site
697329001077	Helicase associated domain; Region: HA; pfam03457
697329001078	Helicase associated domain; Region: HA; pfam03457
697329001079	Helicase associated domain; Region: HA; pfam03457
697329001080	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
697329001081	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329001082	Int/Topo IB signature motif; other site
697329001083	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
697329001084	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329001085	Int/Topo IB signature motif; other site
697329001086	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
697329001087	Protein of unknown function (DUF3849); Region: DUF3849; pfam12960
697329001088	YodL-like; Region: YodL; pfam14191
697329001089	Protein of unknown function (DUF3848); Region: DUF3848; pfam12959
697329001090	Protein of unknown function (DUF3848); Region: DUF3848; pfam12959
697329001091	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
697329001092	Methyltransferase domain; Region: Methyltransf_26; pfam13659
697329001093	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
697329001094	DEAD-like helicases superfamily; Region: DEXDc; smart00487
697329001095	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
697329001096	helicase superfamily c-terminal domain; Region: HELICc; smart00490
697329001097	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
697329001098	DNA topoisomerase III; Provisional; Region: PRK07726
697329001099	active site
697329001100	putative metal-binding site [ion binding]; other site
697329001101	putative interdomain interaction site [polypeptide binding]; other site
697329001102	putative nucleotide binding site [chemical binding]; other site
697329001103	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
697329001104	domain I; other site
697329001105	DNA binding groove [nucleotide binding]
697329001106	phosphate binding site [ion binding]; other site
697329001107	domain II; other site
697329001108	domain III; other site
697329001109	nucleotide binding site [chemical binding]; other site
697329001110	catalytic site [active]
697329001111	domain IV; other site
697329001112	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
697329001113	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
697329001114	Cna protein B-type domain; Region: Cna_B; pfam05738
697329001115	Cna protein B-type domain; Region: Cna_B; pfam05738
697329001116	Cna protein B-type domain; Region: Cna_B; pfam05738
697329001117	Cna protein B-type domain; Region: Cna_B; pfam05738
697329001118	Cna protein B-type domain; Region: Cna_B; pfam05738
697329001119	Cna protein B-type domain; Region: Cna_B; pfam05738
697329001120	Cna protein B-type domain; Region: Cna_B; pfam05738
697329001121	AAA-like domain; Region: AAA_10; pfam12846
697329001122	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329001123	Interdomain contacts; other site
697329001124	Cytokine receptor motif; other site
697329001125	PrgI family protein; Region: PrgI; pfam12666
697329001126	AAA-like domain; Region: AAA_10; pfam12846
697329001127	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
697329001128	Walker A motif; other site
697329001129	ATP binding site [chemical binding]; other site
697329001130	Walker B motif; other site
697329001131	Domain of unknown function (DUF955); Region: DUF955; pfam06114
697329001132	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329001133	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329001134	non-specific DNA binding site [nucleotide binding]; other site
697329001135	salt bridge; other site
697329001136	sequence-specific DNA binding site [nucleotide binding]; other site
697329001137	Domain of unknown function (DUF955); Region: DUF955; pfam06114
697329001138	DNA polymerase IV; Reviewed; Region: PRK03103
697329001139	Y-family of DNA polymerases; Region: PolY; cl12025
697329001140	active site
697329001141	DNA binding site [nucleotide binding]
697329001142	YolD-like protein; Region: YolD; pfam08863
697329001143	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
697329001144	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
697329001145	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
697329001146	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329001147	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329001148	active site
697329001149	DNA binding site [nucleotide binding]
697329001150	Int/Topo IB signature motif; other site
697329001151	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
697329001152	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
697329001153	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
697329001154	HsdM N-terminal domain; Region: HsdM_N; pfam12161
697329001155	Methyltransferase domain; Region: Methyltransf_26; pfam13659
697329001156	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
697329001157	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329001158	ATP binding site [chemical binding]; other site
697329001159	putative Mg++ binding site [ion binding]; other site
697329001160	nucleotide binding region [chemical binding]; other site
697329001161	helicase superfamily c-terminal domain; Region: HELICc; smart00490
697329001162	ATP-binding site [chemical binding]; other site
697329001163	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329001164	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329001165	catalytic residues [active]
697329001166	catalytic nucleophile [active]
697329001167	Recombinase; Region: Recombinase; pfam07508
697329001168	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329001169	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329001170	catalytic residues [active]
697329001171	catalytic nucleophile [active]
697329001172	Recombinase; Region: Recombinase; pfam07508
697329001173	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329001174	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
697329001175	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
697329001176	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329001177	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329001178	catalytic residues [active]
697329001179	catalytic nucleophile [active]
697329001180	Recombinase; Region: Recombinase; pfam07508
697329001181	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329001182	Recombinase; Region: Recombinase; pfam07508
697329001183	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329001184	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329001185	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329001186	catalytic residues [active]
697329001187	catalytic nucleophile [active]
697329001188	Recombinase; Region: Recombinase; pfam07508
697329001189	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329001190	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
697329001191	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329001192	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329001193	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
697329001194	Mg binding site [ion binding]; other site
697329001195	nucleotide binding site [chemical binding]; other site
697329001196	putative protofilament interface [polypeptide binding]; other site
697329001197	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329001198	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329001199	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329001200	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329001201	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329001202	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329001203	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329001204	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
697329001205	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329001206	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329001207	Walker A/P-loop; other site
697329001208	ATP binding site [chemical binding]; other site
697329001209	Q-loop/lid; other site
697329001210	ABC transporter signature motif; other site
697329001211	Walker B; other site
697329001212	D-loop; other site
697329001213	H-loop/switch region; other site
697329001214	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
697329001215	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
697329001216	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
697329001217	HlyD family secretion protein; Region: HlyD_3; pfam13437
697329001218	ammonium transporter; Region: amt; TIGR00836
697329001219	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
697329001220	Nitrogen regulatory protein P-II; Region: P-II; smart00938
697329001221	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
697329001222	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
697329001223	active site
697329001224	tetramer interface [polypeptide binding]; other site
697329001225	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329001226	active site
697329001227	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
697329001228	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
697329001229	HSP70 interaction site [polypeptide binding]; other site
697329001230	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
697329001231	substrate binding site [polypeptide binding]; other site
697329001232	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
697329001233	Zn binding sites [ion binding]; other site
697329001234	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
697329001235	dimer interface [polypeptide binding]; other site
697329001236	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
697329001237	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
697329001238	nucleotide binding site [chemical binding]; other site
697329001239	NEF interaction site [polypeptide binding]; other site
697329001240	SBD interface [polypeptide binding]; other site
697329001241	GrpE; Region: GrpE; pfam01025
697329001242	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
697329001243	dimer interface [polypeptide binding]; other site
697329001244	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
697329001245	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
697329001246	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
697329001247	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
697329001248	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
697329001249	domain interfaces; other site
697329001250	active site
697329001251	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
697329001252	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
697329001253	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
697329001254	catalytic triad [active]
697329001255	Transposase domain (DUF772); Region: DUF772; pfam05598
697329001256	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
697329001257	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
697329001258	Active_site [active]
697329001259	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329001260	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
697329001261	DNA binding site [nucleotide binding]
697329001262	domain linker motif; other site
697329001263	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
697329001264	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
697329001265	Clostripain family; Region: Peptidase_C11; pfam03415
697329001266	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329001267	tryptophan synthase subunit beta; Reviewed; Region: PRK12391
697329001268	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
697329001269	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329001270	catalytic residue [active]
697329001271	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329001272	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
697329001273	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329001274	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329001275	Coenzyme A binding pocket [chemical binding]; other site
697329001276	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
697329001277	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
697329001278	active site
697329001279	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
697329001280	substrate binding site [chemical binding]; other site
697329001281	catalytic residues [active]
697329001282	dimer interface [polypeptide binding]; other site
697329001283	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
697329001284	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
697329001285	AAA domain; Region: AAA_33; pfam13671
697329001286	AAA domain; Region: AAA_17; pfam13207
697329001287	peptide chain release factor 1; Validated; Region: prfA; PRK00591
697329001288	This domain is found in peptide chain release factors; Region: PCRF; smart00937
697329001289	RF-1 domain; Region: RF-1; pfam00472
697329001290	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
697329001291	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
697329001292	active site
697329001293	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
697329001294	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
697329001295	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
697329001296	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
697329001297	CoA-binding site [chemical binding]; other site
697329001298	ATP-binding [chemical binding]; other site
697329001299	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
697329001300	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
697329001301	N-acetyl-D-glucosamine binding site [chemical binding]; other site
697329001302	catalytic residue [active]
697329001303	M18 Peptidase Aminopeptidase I; Region: M18_API; cd05659
697329001304	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
697329001305	oligomer interface [polypeptide binding]; other site
697329001306	putative active site [active]
697329001307	metal binding site [ion binding]; metal-binding site
697329001308	Sporulation factor SpoIIGA; Region: Peptidase_U4; pfam03419
697329001309	sigma-E processing peptidase SpoIIGA; Region: spore_II_GA; TIGR02854
697329001310	sporulation sigma factor SigE; Reviewed; Region: PRK08301
697329001311	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329001312	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329001313	DNA binding residues [nucleotide binding]
697329001314	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329001315	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329001316	dimer interface [polypeptide binding]; other site
697329001317	phosphorylation site [posttranslational modification]
697329001318	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329001319	ATP binding site [chemical binding]; other site
697329001320	Mg2+ binding site [ion binding]; other site
697329001321	G-X-G motif; other site
697329001322	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
697329001323	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
697329001324	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329001325	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329001326	Walker A/P-loop; other site
697329001327	ATP binding site [chemical binding]; other site
697329001328	Q-loop/lid; other site
697329001329	ABC transporter signature motif; other site
697329001330	Walker B; other site
697329001331	D-loop; other site
697329001332	H-loop/switch region; other site
697329001333	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329001334	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329001335	active site
697329001336	phosphorylation site [posttranslational modification]
697329001337	intermolecular recognition site; other site
697329001338	dimerization interface [polypeptide binding]; other site
697329001339	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329001340	DNA binding site [nucleotide binding]
697329001341	polyphosphate:AMP phosphotransferase; Region: poly_P_AMP_trns; TIGR03708
697329001342	Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971
697329001343	Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971
697329001344	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
697329001345	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329001346	Coenzyme A binding pocket [chemical binding]; other site
697329001347	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
697329001348	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
697329001349	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
697329001350	Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]; Region: HemN; COG0635
697329001351	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
697329001352	FeS/SAM binding site; other site
697329001353	HemN C-terminal domain; Region: HemN_C; pfam06969
697329001354	GTP-binding protein LepA; Provisional; Region: PRK05433
697329001355	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
697329001356	G1 box; other site
697329001357	putative GEF interaction site [polypeptide binding]; other site
697329001358	GTP/Mg2+ binding site [chemical binding]; other site
697329001359	Switch I region; other site
697329001360	G2 box; other site
697329001361	G3 box; other site
697329001362	Switch II region; other site
697329001363	G4 box; other site
697329001364	G5 box; other site
697329001365	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
697329001366	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
697329001367	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
697329001368	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329001369	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
697329001370	catalytic residues [active]
697329001371	catalytic nucleophile [active]
697329001372	Helix-turn-helix domain; Region: HTH_36; pfam13730
697329001373	Transcriptional regulator; Region: Rrf2; cl17282
697329001374	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
697329001375	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329001376	active site
697329001377	phosphorylation site [posttranslational modification]
697329001378	intermolecular recognition site; other site
697329001379	dimerization interface [polypeptide binding]; other site
697329001380	LytTr DNA-binding domain; Region: LytTR; pfam04397
697329001381	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
697329001382	Cys-rich peptide radical SAM maturase CcpM; Region: rSAM_ocin_clost; TIGR04068
697329001383	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329001384	FeS/SAM binding site; other site
697329001385	Radical SAM superfamily; Region: Radical_SAM; pfam04055
697329001386	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329001387	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329001388	Walker A/P-loop; other site
697329001389	ATP binding site [chemical binding]; other site
697329001390	Q-loop/lid; other site
697329001391	ABC transporter signature motif; other site
697329001392	Walker B; other site
697329001393	D-loop; other site
697329001394	H-loop/switch region; other site
697329001395	CAAX protease self-immunity; Region: Abi; pfam02517
697329001396	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
697329001397	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329001398	salt bridge; other site
697329001399	non-specific DNA binding site [nucleotide binding]; other site
697329001400	sequence-specific DNA binding site [nucleotide binding]; other site
697329001401	Conjugal transfer protein TraD; Region: TraD; cl05753
697329001402	GIY-YIG catalytic domain; Region: GIY-YIG; pfam01541
697329001403	GIY-YIG motif/motif A; other site
697329001404	active site
697329001405	catalytic site [active]
697329001406	metal binding site [ion binding]; metal-binding site
697329001407	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
697329001408	nucleotide binding site [chemical binding]; other site
697329001409	Eukaryotic and archaeal DNA primase small subunit; Region: DNA_primase_S; pfam01896
697329001410	synthase/transferase; Region: PLN02316
697329001411	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
697329001412	DnaA N-terminal domain; Region: DnaA_N; pfam11638
697329001413	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329001414	Walker A motif; other site
697329001415	ATP binding site [chemical binding]; other site
697329001416	Walker B motif; other site
697329001417	arginine finger; other site
697329001418	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
697329001419	DnaA box-binding interface [nucleotide binding]; other site
697329001420	DNA polymerase III subunit beta; Validated; Region: PRK05643
697329001421	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
697329001422	putative DNA binding surface [nucleotide binding]; other site
697329001423	dimer interface [polypeptide binding]; other site
697329001424	beta-clamp/clamp loader binding surface; other site
697329001425	beta-clamp/translesion DNA polymerase binding surface; other site
697329001426	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329001427	RNA binding surface [nucleotide binding]; other site
697329001428	recombination protein F; Reviewed; Region: recF; PRK00064
697329001429	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329001430	Walker A/P-loop; other site
697329001431	ATP binding site [chemical binding]; other site
697329001432	Q-loop/lid; other site
697329001433	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329001434	ABC transporter signature motif; other site
697329001435	Walker B; other site
697329001436	D-loop; other site
697329001437	H-loop/switch region; other site
697329001438	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
697329001439	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329001440	Mg2+ binding site [ion binding]; other site
697329001441	G-X-G motif; other site
697329001442	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
697329001443	anchoring element; other site
697329001444	dimer interface [polypeptide binding]; other site
697329001445	ATP binding site [chemical binding]; other site
697329001446	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
697329001447	active site
697329001448	putative metal-binding site [ion binding]; other site
697329001449	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
697329001450	DNA gyrase subunit A; Validated; Region: PRK05560
697329001451	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
697329001452	CAP-like domain; other site
697329001453	active site
697329001454	primary dimer interface [polypeptide binding]; other site
697329001455	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
697329001456	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
697329001457	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
697329001458	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
697329001459	Double zinc ribbon; Region: DZR; pfam12773
697329001460	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
697329001461	ParB-like nuclease domain; Region: ParB; smart00470
697329001462	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
697329001463	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
697329001464	P-loop; other site
697329001465	Magnesium ion binding site [ion binding]; other site
697329001466	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
697329001467	Magnesium ion binding site [ion binding]; other site
697329001468	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
697329001469	ParB-like nuclease domain; Region: ParBc; pfam02195
697329001470	KorB domain; Region: KorB; pfam08535
697329001471	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
697329001472	DEAD/DEAH box helicase; Region: DEAD; pfam00270
697329001473	ATP binding site [chemical binding]; other site
697329001474	putative Mg++ binding site [ion binding]; other site
697329001475	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
697329001476	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
697329001477	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
697329001478	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
697329001479	shikimate binding site; other site
697329001480	NAD(P) binding site [chemical binding]; other site
697329001481	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
697329001482	dimerization interface [polypeptide binding]; other site
697329001483	putative active cleft [active]
697329001484	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase; Region: PHP_HisPPase; cd07432
697329001485	active site
697329001486	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
697329001487	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329001488	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
697329001489	Uncharacterized conserved protein [Function unknown]; Region: COG4198
697329001490	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
697329001491	CotH protein; Region: CotH; pfam08757
697329001492	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
697329001493	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
697329001494	Glucosyl transferase GtrII; Region: Glucos_trans_II; cl10304
697329001495	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
697329001496	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
697329001497	Ligand binding site; other site
697329001498	Putative Catalytic site; other site
697329001499	DXD motif; other site
697329001500	BNR repeat-like domain; Region: BNR_2; pfam13088
697329001501	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
697329001502	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
697329001503	active site
697329001504	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
697329001505	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
697329001506	dimer interface [polypeptide binding]; other site
697329001507	PYR/PP interface [polypeptide binding]; other site
697329001508	TPP binding site [chemical binding]; other site
697329001509	substrate binding site [chemical binding]; other site
697329001510	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
697329001511	Domain of unknown function; Region: EKR; pfam10371
697329001512	4Fe-4S binding domain; Region: Fer4_6; pfam12837
697329001513	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
697329001514	TPP-binding site [chemical binding]; other site
697329001515	dimer interface [polypeptide binding]; other site
697329001516	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
697329001517	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
697329001518	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329001519	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329001520	non-specific DNA binding site [nucleotide binding]; other site
697329001521	salt bridge; other site
697329001522	sequence-specific DNA binding site [nucleotide binding]; other site
697329001523	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
697329001524	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
697329001525	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
697329001526	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
697329001527	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
697329001528	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
697329001529	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
697329001530	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
697329001531	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
697329001532	putative translocon binding site; other site
697329001533	protein-rRNA interface [nucleotide binding]; other site
697329001534	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
697329001535	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
697329001536	G-X-X-G motif; other site
697329001537	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
697329001538	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
697329001539	23S rRNA interface [nucleotide binding]; other site
697329001540	5S rRNA interface [nucleotide binding]; other site
697329001541	putative antibiotic binding site [chemical binding]; other site
697329001542	L25 interface [polypeptide binding]; other site
697329001543	L27 interface [polypeptide binding]; other site
697329001544	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
697329001545	23S rRNA interface [nucleotide binding]; other site
697329001546	putative translocon interaction site; other site
697329001547	signal recognition particle (SRP54) interaction site; other site
697329001548	L23 interface [polypeptide binding]; other site
697329001549	trigger factor interaction site; other site
697329001550	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
697329001551	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
697329001552	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
697329001553	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
697329001554	RNA binding site [nucleotide binding]; other site
697329001555	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
697329001556	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
697329001557	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
697329001558	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
697329001559	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
697329001560	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
697329001561	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
697329001562	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
697329001563	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
697329001564	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
697329001565	23S rRNA interface [nucleotide binding]; other site
697329001566	L21e interface [polypeptide binding]; other site
697329001567	5S rRNA interface [nucleotide binding]; other site
697329001568	L27 interface [polypeptide binding]; other site
697329001569	L5 interface [polypeptide binding]; other site
697329001570	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
697329001571	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
697329001572	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
697329001573	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
697329001574	23S rRNA binding site [nucleotide binding]; other site
697329001575	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
697329001576	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
697329001577	SecY translocase; Region: SecY; pfam00344
697329001578	adenylate kinase; Reviewed; Region: adk; PRK00279
697329001579	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
697329001580	AMP-binding site [chemical binding]; other site
697329001581	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
697329001582	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
697329001583	active site
697329001584	KOW motif of Ribosomal Protein L14; Region: KOW_RPL14; cd06088
697329001585	RNA binding site [nucleotide binding]; other site
697329001586	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
697329001587	rRNA binding site [nucleotide binding]; other site
697329001588	predicted 30S ribosome binding site; other site
697329001589	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
697329001590	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
697329001591	30S ribosomal protein S13; Region: bact_S13; TIGR03631
697329001592	30S ribosomal protein S11; Validated; Region: PRK05309
697329001593	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
697329001594	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
697329001595	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329001596	RNA binding surface [nucleotide binding]; other site
697329001597	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
697329001598	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
697329001599	alphaNTD - beta interaction site [polypeptide binding]; other site
697329001600	alphaNTD homodimer interface [polypeptide binding]; other site
697329001601	alphaNTD - beta' interaction site [polypeptide binding]; other site
697329001602	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
697329001603	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
697329001604	Predicted membrane protein [Function unknown]; Region: COG2246
697329001605	GtrA-like protein; Region: GtrA; pfam04138
697329001606	maltose O-acetyltransferase; Provisional; Region: PRK10092
697329001607	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
697329001608	active site
697329001609	substrate binding site [chemical binding]; other site
697329001610	trimer interface [polypeptide binding]; other site
697329001611	CoA binding site [chemical binding]; other site
697329001612	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
697329001613	catalytic motif [active]
697329001614	Zn binding site [ion binding]; other site
697329001615	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
697329001616	23S rRNA interface [nucleotide binding]; other site
697329001617	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
697329001618	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
697329001619	core dimer interface [polypeptide binding]; other site
697329001620	peripheral dimer interface [polypeptide binding]; other site
697329001621	L10 interface [polypeptide binding]; other site
697329001622	L11 interface [polypeptide binding]; other site
697329001623	putative EF-Tu interaction site [polypeptide binding]; other site
697329001624	putative EF-G interaction site [polypeptide binding]; other site
697329001625	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
697329001626	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329001627	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cl17565
697329001628	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
697329001629	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
697329001630	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329001631	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329001632	Walker A/P-loop; other site
697329001633	ATP binding site [chemical binding]; other site
697329001634	Q-loop/lid; other site
697329001635	ABC transporter signature motif; other site
697329001636	Walker B; other site
697329001637	D-loop; other site
697329001638	H-loop/switch region; other site
697329001639	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
697329001640	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
697329001641	dimer interface [polypeptide binding]; other site
697329001642	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329001643	catalytic residue [active]
697329001644	CheW-like domain; Region: CheW; pfam01584
697329001645	Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain [Cell motility and secretion / Signal transduction mechanisms]; Region: CheB; COG2201
697329001646	CheB methylesterase; Region: CheB_methylest; pfam01339
697329001647	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
697329001648	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
697329001649	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
697329001650	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
697329001651	Clp amino terminal domain; Region: Clp_N; pfam02861
697329001652	Clp amino terminal domain; Region: Clp_N; pfam02861
697329001653	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329001654	Walker A motif; other site
697329001655	ATP binding site [chemical binding]; other site
697329001656	Walker B motif; other site
697329001657	arginine finger; other site
697329001658	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329001659	Walker A motif; other site
697329001660	ATP binding site [chemical binding]; other site
697329001661	Walker B motif; other site
697329001662	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
697329001663	DHHW protein; Region: DHHW; pfam14286
697329001664	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
697329001665	phosphoglyceromutase; Provisional; Region: PRK05434
697329001666	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
697329001667	catalytic core [active]
697329001668	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
697329001669	triosephosphate isomerase; Provisional; Region: PRK14567
697329001670	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
697329001671	substrate binding site [chemical binding]; other site
697329001672	dimer interface [polypeptide binding]; other site
697329001673	catalytic triad [active]
697329001674	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
697329001675	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
697329001676	trmE is a tRNA modification GTPase; Region: trmE; cd04164
697329001677	G1 box; other site
697329001678	GTP/Mg2+ binding site [chemical binding]; other site
697329001679	Switch I region; other site
697329001680	G2 box; other site
697329001681	Switch II region; other site
697329001682	G3 box; other site
697329001683	G4 box; other site
697329001684	G5 box; other site
697329001685	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
697329001686	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
697329001687	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
697329001688	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
697329001689	seryl-tRNA synthetase; Provisional; Region: PRK05431
697329001690	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
697329001691	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
697329001692	motif 1; other site
697329001693	dimer interface [polypeptide binding]; other site
697329001694	active site
697329001695	motif 2; other site
697329001696	motif 3; other site
697329001697	Septum formation initiator; Region: DivIC; cl17659
697329001698	hypothetical protein; Provisional; Region: PRK08582
697329001699	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
697329001700	RNA binding site [nucleotide binding]; other site
697329001701	Domain of unknown function (DUF377); Region: DUF377; pfam04041
697329001702	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
697329001703	active site
697329001704	prolyl-tRNA synthetase; Provisional; Region: PRK08661
697329001705	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
697329001706	dimer interface [polypeptide binding]; other site
697329001707	motif 1; other site
697329001708	active site
697329001709	motif 2; other site
697329001710	motif 3; other site
697329001711	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
697329001712	anticodon binding site; other site
697329001713	zinc-binding site [ion binding]; other site
697329001714	Photosystem I psaG / psaK; Region: PSI_PSAK; cl11425
697329001715	TIGR04076 family protein; Region: TIGR04076
697329001716	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
697329001717	Domain of unknown function (DUF4358); Region: DUF4358; pfam14270
697329001718	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
697329001719	active site
697329001720	catalytic triad [active]
697329001721	oxyanion hole [active]
697329001722	Domain of unknown function (DUF1851); Region: DUF1851; pfam08906
697329001723	Maf-like protein; Region: Maf; pfam02545
697329001724	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
697329001725	active site
697329001726	dimer interface [polypeptide binding]; other site
697329001727	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
697329001728	Bacterial SH3 domain; Region: SH3_3; pfam08239
697329001729	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
697329001730	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
697329001731	active site
697329001732	catalytic site [active]
697329001733	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
697329001734	active site
697329001735	catalytic site [active]
697329001736	Competence-damaged protein; Region: CinA; pfam02464
697329001737	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
697329001738	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
697329001739	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
697329001740	Ligand Binding Site [chemical binding]; other site
697329001741	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
697329001742	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
697329001743	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329001744	catalytic residue [active]
697329001745	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
697329001746	active site
697329001747	catalytic motif [active]
697329001748	Zn binding site [ion binding]; other site
697329001749	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
697329001750	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
697329001751	ring oligomerisation interface [polypeptide binding]; other site
697329001752	ATP/Mg binding site [chemical binding]; other site
697329001753	stacking interactions; other site
697329001754	hinge regions; other site
697329001755	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
697329001756	oligomerisation interface [polypeptide binding]; other site
697329001757	mobile loop; other site
697329001758	roof hairpin; other site
697329001759	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329001760	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329001761	active site
697329001762	phosphorylation site [posttranslational modification]
697329001763	intermolecular recognition site; other site
697329001764	dimerization interface [polypeptide binding]; other site
697329001765	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329001766	DNA binding site [nucleotide binding]
697329001767	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329001768	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
697329001769	dimerization interface [polypeptide binding]; other site
697329001770	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329001771	dimer interface [polypeptide binding]; other site
697329001772	phosphorylation site [posttranslational modification]
697329001773	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329001774	ATP binding site [chemical binding]; other site
697329001775	Mg2+ binding site [ion binding]; other site
697329001776	G-X-G motif; other site
697329001777	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
697329001778	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
697329001779	protein binding site [polypeptide binding]; other site
697329001780	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
697329001781	active site
697329001782	catalytic triad [active]
697329001783	oxyanion hole [active]
697329001784	Uncharacterized conserved protein [Function unknown]; Region: COG0327
697329001785	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
697329001786	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
697329001787	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
697329001788	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329001789	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329001790	Walker A/P-loop; other site
697329001791	ATP binding site [chemical binding]; other site
697329001792	Q-loop/lid; other site
697329001793	ABC transporter signature motif; other site
697329001794	Walker B; other site
697329001795	D-loop; other site
697329001796	H-loop/switch region; other site
697329001797	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
697329001798	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
697329001799	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
697329001800	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
697329001801	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329001802	FtsX-like permease family; Region: FtsX; pfam02687
697329001803	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
697329001804	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
697329001805	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
697329001806	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
697329001807	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
697329001808	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329001809	non-specific DNA binding site [nucleotide binding]; other site
697329001810	salt bridge; other site
697329001811	sequence-specific DNA binding site [nucleotide binding]; other site
697329001812	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
697329001813	catalytic core [active]
697329001814	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
697329001815	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
697329001816	active site
697329001817	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
697329001818	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
697329001819	ADP binding site [chemical binding]; other site
697329001820	magnesium binding site [ion binding]; other site
697329001821	putative shikimate binding site; other site
697329001822	Family of unknown function (DUF633); Region: DUF633; pfam04816
697329001823	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
697329001824	active site
697329001825	oxyanion hole [active]
697329001826	catalytic triad [active]
697329001827	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
697329001828	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
697329001829	glutaminase active site [active]
697329001830	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
697329001831	dimer interface [polypeptide binding]; other site
697329001832	active site
697329001833	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
697329001834	dimer interface [polypeptide binding]; other site
697329001835	active site
697329001836	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
697329001837	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
697329001838	nudix motif; other site
697329001839	Domain of unknown function (DUF1910); Region: DUF1910; pfam08928
697329001840	Domain of unknown function (DUF1911); Region: DUF1911; pfam08929
697329001841	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
697329001842	Melibiase; Region: Melibiase; pfam02065
697329001843	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
697329001844	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
697329001845	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329001846	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001847	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001848	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001849	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001850	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001851	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329001852	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001853	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001854	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001855	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329001856	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001857	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001858	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001859	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001860	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001861	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329001862	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001863	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001864	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001865	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329001866	Interdomain contacts; other site
697329001867	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329001868	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329001869	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329001870	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001871	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001872	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001873	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329001874	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001875	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001876	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001877	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001878	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329001879	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329001880	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
697329001881	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
697329001882	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329001883	active site
697329001884	phosphorylation site [posttranslational modification]
697329001885	intermolecular recognition site; other site
697329001886	dimerization interface [polypeptide binding]; other site
697329001887	LytTr DNA-binding domain; Region: LytTR; smart00850
697329001888	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
697329001889	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
697329001890	ATP binding site [chemical binding]; other site
697329001891	Mg2+ binding site [ion binding]; other site
697329001892	G-X-G motif; other site
697329001893	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
697329001894	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329001895	FeS/SAM binding site; other site
697329001896	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
697329001897	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
697329001898	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329001899	FeS/SAM binding site; other site
697329001900	CXXX repeat peptide maturase; Region: CXXX_matur; TIGR04119
697329001901	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
697329001902	active site
697329001903	catalytic residues [active]
697329001904	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329001905	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329001906	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329001907	Walker A/P-loop; other site
697329001908	ATP binding site [chemical binding]; other site
697329001909	Q-loop/lid; other site
697329001910	ABC transporter signature motif; other site
697329001911	Walker B; other site
697329001912	D-loop; other site
697329001913	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329001914	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329001915	Walker A/P-loop; other site
697329001916	ATP binding site [chemical binding]; other site
697329001917	Q-loop/lid; other site
697329001918	ABC transporter signature motif; other site
697329001919	Walker B; other site
697329001920	D-loop; other site
697329001921	H-loop/switch region; other site
697329001922	FtsX-like permease family; Region: FtsX; pfam02687
697329001923	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329001924	FtsX-like permease family; Region: FtsX; pfam02687
697329001925	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
697329001926	trimer interface [polypeptide binding]; other site
697329001927	active site
697329001928	aldose 1-epimerase superfamily; Region: Aldose_epim; cd01081
697329001929	active site
697329001930	catalytic residues [active]
697329001931	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
697329001932	N-terminal domain of cellobiose phosphorylase (CBP) and similar proteins; Region: GH94N_CBP_like; cd11754
697329001933	catalytic domain interface [polypeptide binding]; other site
697329001934	homodimer interface [polypeptide binding]; other site
697329001935	putative active site [active]
697329001936	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
697329001937	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
697329001938	active site
697329001939	HIGH motif; other site
697329001940	KMSKS motif; other site
697329001941	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
697329001942	tRNA binding surface [nucleotide binding]; other site
697329001943	anticodon binding site; other site
697329001944	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
697329001945	dimer interface [polypeptide binding]; other site
697329001946	putative tRNA-binding site [nucleotide binding]; other site
697329001947	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
697329001948	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
697329001949	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
697329001950	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
697329001951	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
697329001952	substrate binding site [chemical binding]; other site
697329001953	ATP binding site [chemical binding]; other site
697329001954	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
697329001955	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
697329001956	active site
697329001957	intersubunit interface [polypeptide binding]; other site
697329001958	catalytic residue [active]
697329001959	Glucuronate isomerase; Region: UxaC; pfam02614
697329001960	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
697329001961	mannonate dehydratase; Provisional; Region: PRK03906
697329001962	mannonate dehydratase; Region: uxuA; TIGR00695
697329001963	hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980
697329001964	Rubrerythrin [Energy production and conversion]; Region: COG1592
697329001965	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
697329001966	binuclear metal center [ion binding]; other site
697329001967	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
697329001968	iron binding site [ion binding]; other site
697329001969	germination protein YpeB; Region: spore_YpeB; TIGR02889
697329001970	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
697329001971	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
697329001972	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329001973	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329001974	Walker A/P-loop; other site
697329001975	ATP binding site [chemical binding]; other site
697329001976	Q-loop/lid; other site
697329001977	ABC transporter signature motif; other site
697329001978	Walker B; other site
697329001979	D-loop; other site
697329001980	H-loop/switch region; other site
697329001981	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
697329001982	DHHW protein; Region: DHHW; pfam14286
697329001983	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FkbH; COG3882
697329001984	Acid Phosphatase; Region: Acid_PPase; cl17256
697329001985	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
697329001986	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
697329001987	dimer interface [polypeptide binding]; other site
697329001988	substrate binding site [chemical binding]; other site
697329001989	metal binding sites [ion binding]; metal-binding site
697329001990	N2227-like protein; Region: N2227; pfam07942
697329001991	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329001992	S-adenosylmethionine binding site [chemical binding]; other site
697329001993	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
697329001994	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
697329001995	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
697329001996	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
697329001997	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
697329001998	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329001999	metal binding site [ion binding]; metal-binding site
697329002000	active site
697329002001	I-site; other site
697329002002	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329002003	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
697329002004	active site
697329002005	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, clostridial; Region: rSAM_QueE_Clost; TIGR03963
697329002006	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329002007	FeS/SAM binding site; other site
697329002008	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
697329002009	GTP cyclohydrolase I; Provisional; Region: PLN03044
697329002010	active site
697329002011	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
697329002012	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
697329002013	Ligand Binding Site [chemical binding]; other site
697329002014	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
697329002015	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
697329002016	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
697329002017	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
697329002018	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cd02062
697329002019	FMN binding site [chemical binding]; other site
697329002020	dimer interface [polypeptide binding]; other site
697329002021	macrophage migration inhibition factor-like protein; Provisional; Region: PTZ00397
697329002022	UGMP family protein; Validated; Region: PRK09604
697329002023	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
697329002024	GNAT acetyltransferase; Region: GNAT_acetyltran; pfam12746
697329002025	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
697329002026	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329002027	Coenzyme A binding pocket [chemical binding]; other site
697329002028	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329002029	Methyltransferase domain; Region: Methyltransf_23; pfam13489
697329002030	Methyltransferase domain; Region: Methyltransf_11; pfam08241
697329002031	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
697329002032	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
697329002033	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329002034	homodimer interface [polypeptide binding]; other site
697329002035	catalytic residue [active]
697329002036	GAF domain; Region: GAF; pfam01590
697329002037	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329002038	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329002039	metal binding site [ion binding]; metal-binding site
697329002040	active site
697329002041	I-site; other site
697329002042	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
697329002043	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329002044	Zn2+ binding site [ion binding]; other site
697329002045	Mg2+ binding site [ion binding]; other site
697329002046	Ketopantoate reductase [Coenzyme metabolism]; Region: ApbA; COG1893
697329002047	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
697329002048	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
697329002049	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329002050	dimer interface [polypeptide binding]; other site
697329002051	conserved gate region; other site
697329002052	putative PBP binding loops; other site
697329002053	ABC-ATPase subunit interface; other site
697329002054	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
697329002055	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329002056	dimer interface [polypeptide binding]; other site
697329002057	conserved gate region; other site
697329002058	putative PBP binding loops; other site
697329002059	ABC-ATPase subunit interface; other site
697329002060	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329002061	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
697329002062	stage V sporulation protein T; Region: spore_V_T; TIGR02851
697329002063	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
697329002064	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
697329002065	homodimer interaction site [polypeptide binding]; other site
697329002066	cofactor binding site; other site
697329002067	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
697329002068	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
697329002069	Pyocin large subunit [General function prediction only]; Region: COG5529
697329002070	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
697329002071	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
697329002072	alanine racemase; Reviewed; Region: alr; PRK00053
697329002073	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
697329002074	active site
697329002075	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
697329002076	dimer interface [polypeptide binding]; other site
697329002077	substrate binding site [chemical binding]; other site
697329002078	catalytic residues [active]
697329002079	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329002080	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329002081	metal binding site [ion binding]; metal-binding site
697329002082	active site
697329002083	I-site; other site
697329002084	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
697329002085	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
697329002086	putative dimer interface [polypeptide binding]; other site
697329002087	Germination protease; Region: Peptidase_A25; cl04057
697329002088	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
697329002089	Transcriptional regulators [Transcription]; Region: MarR; COG1846
697329002090	MarR family; Region: MarR_2; pfam12802
697329002091	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329002092	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329002093	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329002094	Walker A/P-loop; other site
697329002095	ATP binding site [chemical binding]; other site
697329002096	Q-loop/lid; other site
697329002097	ABC transporter signature motif; other site
697329002098	Walker B; other site
697329002099	D-loop; other site
697329002100	H-loop/switch region; other site
697329002101	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329002102	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329002103	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
697329002104	Walker A/P-loop; other site
697329002105	ATP binding site [chemical binding]; other site
697329002106	Q-loop/lid; other site
697329002107	ABC transporter signature motif; other site
697329002108	Walker B; other site
697329002109	D-loop; other site
697329002110	H-loop/switch region; other site
697329002111	homoserine kinase; Provisional; Region: PRK01212
697329002112	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
697329002113	radical SAM protein, TatD family-associated; Region: tatD_link_rSAM; TIGR04038
697329002114	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329002115	FeS/SAM binding site; other site
697329002116	glycogen synthase; Provisional; Region: glgA; PRK00654
697329002117	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
697329002118	ADP-binding pocket [chemical binding]; other site
697329002119	homodimer interface [polypeptide binding]; other site
697329002120	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
697329002121	ligand binding site; other site
697329002122	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
697329002123	oligomer interface; other site
697329002124	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
697329002125	dimer interface [polypeptide binding]; other site
697329002126	N-terminal domain interface [polypeptide binding]; other site
697329002127	sulfate 1 binding site; other site
697329002128	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
697329002129	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
697329002130	ligand binding site; other site
697329002131	oligomer interface; other site
697329002132	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
697329002133	dimer interface [polypeptide binding]; other site
697329002134	N-terminal domain interface [polypeptide binding]; other site
697329002135	sulfate 1 binding site; other site
697329002136	glycogen branching enzyme; Provisional; Region: PRK12313
697329002137	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
697329002138	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
697329002139	active site
697329002140	catalytic site [active]
697329002141	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
697329002142	stage II sporulation protein E; Region: spore_II_E; TIGR02865
697329002143	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
697329002144	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
697329002145	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
697329002146	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329002147	S-adenosylmethionine binding site [chemical binding]; other site
697329002148	AIR carboxylase; Region: AIRC; pfam00731
697329002149	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
697329002150	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329002151	motif II; other site
697329002152	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
697329002153	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
697329002154	ATP binding site [chemical binding]; other site
697329002155	active site
697329002156	substrate binding site [chemical binding]; other site
697329002157	amidophosphoribosyltransferase; Provisional; Region: PRK06781
697329002158	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
697329002159	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329002160	active site
697329002161	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
697329002162	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
697329002163	dimerization interface [polypeptide binding]; other site
697329002164	putative ATP binding site [chemical binding]; other site
697329002165	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
697329002166	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
697329002167	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
697329002168	active site
697329002169	substrate binding site [chemical binding]; other site
697329002170	cosubstrate binding site; other site
697329002171	catalytic site [active]
697329002172	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
697329002173	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
697329002174	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
697329002175	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
697329002176	5-aminoimidazole-4-carboxamide ribonucleotide transformylase; Provisional; Region: PRK07106
697329002177	AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]; Region: PurH; COG0138
697329002178	Uncharacterized protein family (UPF0167); Region: UPF0167; pfam03691
697329002179	DNA topoisomerase I; Validated; Region: PRK07219
697329002180	IMP cyclohydrolase-like protein; Region: IMP_cyclohyd; cl01330
697329002181	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
697329002182	Bacterial PH domain; Region: DUF304; pfam03703
697329002183	Bacterial PH domain; Region: DUF304; cl01348
697329002184	Bacterial PH domain; Region: DUF304; cl01348
697329002185	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
697329002186	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
697329002187	putative binding surface; other site
697329002188	active site
697329002189	P2 response regulator binding domain; Region: P2; pfam07194
697329002190	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
697329002191	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329002192	ATP binding site [chemical binding]; other site
697329002193	Mg2+ binding site [ion binding]; other site
697329002194	G-X-G motif; other site
697329002195	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
697329002196	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
697329002197	DNA polymerase I; Provisional; Region: PRK05755
697329002198	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
697329002199	active site
697329002200	metal binding site 1 [ion binding]; metal-binding site
697329002201	putative 5' ssDNA interaction site; other site
697329002202	metal binding site 3; metal-binding site
697329002203	metal binding site 2 [ion binding]; metal-binding site
697329002204	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
697329002205	putative DNA binding site [nucleotide binding]; other site
697329002206	putative metal binding site [ion binding]; other site
697329002207	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
697329002208	active site
697329002209	substrate binding site [chemical binding]; other site
697329002210	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
697329002211	active site
697329002212	DNA binding site [nucleotide binding]
697329002213	catalytic site [active]
697329002214	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
697329002215	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329002216	RNA binding surface [nucleotide binding]; other site
697329002217	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
697329002218	active site
697329002219	4-alpha-glucanotransferase; Provisional; Region: PRK14508
697329002220	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
697329002221	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
697329002222	gamma subunit interface [polypeptide binding]; other site
697329002223	epsilon subunit interface [polypeptide binding]; other site
697329002224	LBP interface [polypeptide binding]; other site
697329002225	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
697329002226	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
697329002227	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
697329002228	alpha subunit interaction interface [polypeptide binding]; other site
697329002229	Walker A motif; other site
697329002230	ATP binding site [chemical binding]; other site
697329002231	Walker B motif; other site
697329002232	inhibitor binding site; inhibition site
697329002233	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
697329002234	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
697329002235	core domain interface [polypeptide binding]; other site
697329002236	delta subunit interface [polypeptide binding]; other site
697329002237	epsilon subunit interface [polypeptide binding]; other site
697329002238	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
697329002239	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
697329002240	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
697329002241	beta subunit interaction interface [polypeptide binding]; other site
697329002242	Walker A motif; other site
697329002243	ATP binding site [chemical binding]; other site
697329002244	Walker B motif; other site
697329002245	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
697329002246	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
697329002247	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
697329002248	F0F1 ATP synthase subunit B; Provisional; Region: PRK13461
697329002249	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
697329002250	ATP synthase subunit C; Region: ATP-synt_C; cl00466
697329002251	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
697329002252	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
697329002253	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329002254	putative metal binding site [ion binding]; other site
697329002255	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329002256	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
697329002257	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329002258	active site
697329002259	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329002260	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
697329002261	LexA repressor; Validated; Region: PRK00215
697329002262	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
697329002263	Catalytic site [active]
697329002264	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
697329002265	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
697329002266	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
697329002267	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
697329002268	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329002269	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329002270	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329002271	Walker A/P-loop; other site
697329002272	ATP binding site [chemical binding]; other site
697329002273	Q-loop/lid; other site
697329002274	ABC transporter signature motif; other site
697329002275	Walker B; other site
697329002276	D-loop; other site
697329002277	H-loop/switch region; other site
697329002278	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329002279	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329002280	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
697329002281	Walker A/P-loop; other site
697329002282	ATP binding site [chemical binding]; other site
697329002283	Q-loop/lid; other site
697329002284	ABC transporter signature motif; other site
697329002285	Walker B; other site
697329002286	D-loop; other site
697329002287	H-loop/switch region; other site
697329002288	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002289	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002290	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002291	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002292	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002293	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002294	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002295	YabP family; Region: YabP; cl06766
697329002296	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
697329002297	MBOAT, membrane-bound O-acyltransferase family; Region: MBOAT; cl00738
697329002298	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
697329002299	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329002300	NAD(P) binding site [chemical binding]; other site
697329002301	active site
697329002302	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329002303	non-specific DNA binding site [nucleotide binding]; other site
697329002304	salt bridge; other site
697329002305	sequence-specific DNA binding site [nucleotide binding]; other site
697329002306	pyruvate phosphate dikinase; Provisional; Region: PRK09279
697329002307	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
697329002308	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
697329002309	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
697329002310	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329002311	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329002312	ligand binding site [chemical binding]; other site
697329002313	dimerization interface [polypeptide binding]; other site
697329002314	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329002315	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329002316	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329002317	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329002318	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
697329002319	active site
697329002320	catalytic triad [active]
697329002321	oxyanion hole [active]
697329002322	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329002323	Interdomain contacts; other site
697329002324	Ferric reductase like transmembrane component; Region: Ferric_reduct; cl01043
697329002325	FMN-binding domain; Region: FMN_bind; pfam04205
697329002326	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
697329002327	ApbE family; Region: ApbE; pfam02424
697329002328	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
697329002329	trimer interface [polypeptide binding]; other site
697329002330	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
697329002331	Protein of unknown function (DUF1533); Region: DUF1533; pfam07550
697329002332	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002333	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002334	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002335	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002336	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329002337	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329002338	ATP binding site [chemical binding]; other site
697329002339	Mg2+ binding site [ion binding]; other site
697329002340	G-X-G motif; other site
697329002341	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
697329002342	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329002343	active site
697329002344	phosphorylation site [posttranslational modification]
697329002345	intermolecular recognition site; other site
697329002346	dimerization interface [polypeptide binding]; other site
697329002347	Class I aldolases; Region: Aldolase_Class_I; cl17187
697329002348	LytTr DNA-binding domain; Region: LytTR; smart00850
697329002349	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329002350	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329002351	Uncharacterized conserved protein [Function unknown]; Region: COG3603
697329002352	Family description; Region: ACT_7; pfam13840
697329002353	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
697329002354	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
697329002355	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329002356	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329002357	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329002358	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329002359	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329002360	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329002361	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329002362	VanW like protein; Region: VanW; pfam04294
697329002363	indolepyruvate oxidoreductase subunit beta; Reviewed; Region: PRK06853
697329002364	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
697329002365	indolepyruvate ferredoxin oxidoreductase, alpha subunit; Region: IOR_alpha; TIGR03336
697329002366	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
697329002367	dimer interface [polypeptide binding]; other site
697329002368	PYR/PP interface [polypeptide binding]; other site
697329002369	TPP binding site [chemical binding]; other site
697329002370	substrate binding site [chemical binding]; other site
697329002371	Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008
697329002372	TPP-binding site; other site
697329002373	4Fe-4S binding domain; Region: Fer4; pfam00037
697329002374	pullulanase, type I; Region: pulA_typeI; TIGR02104
697329002375	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
697329002376	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
697329002377	Ca binding site [ion binding]; other site
697329002378	active site
697329002379	catalytic site [active]
697329002380	Domain of unknown function (DUF3372); Region: DUF3372; pfam11852
697329002381	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
697329002382	Phosphatidylserine decarboxylase; Region: PS_Dcarbxylase; cl03656
697329002383	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; cl01757
697329002384	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
697329002385	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
697329002386	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
697329002387	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
697329002388	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
697329002389	Mg++ binding site [ion binding]; other site
697329002390	putative catalytic motif [active]
697329002391	putative substrate binding site [chemical binding]; other site
697329002392	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
697329002393	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329002394	Walker A/P-loop; other site
697329002395	ATP binding site [chemical binding]; other site
697329002396	Q-loop/lid; other site
697329002397	ABC transporter signature motif; other site
697329002398	Walker B; other site
697329002399	D-loop; other site
697329002400	H-loop/switch region; other site
697329002401	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
697329002402	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329002403	non-specific DNA binding site [nucleotide binding]; other site
697329002404	salt bridge; other site
697329002405	sequence-specific DNA binding site [nucleotide binding]; other site
697329002406	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
697329002407	Transposase; Region: DEDD_Tnp_IS110; pfam01548
697329002408	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
697329002409	CAAX protease self-immunity; Region: Abi; pfam02517
697329002410	fumarate hydratase; Provisional; Region: PRK06246
697329002411	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329002412	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329002413	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329002414	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329002415	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329002416	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329002417	ATP binding site [chemical binding]; other site
697329002418	putative Mg++ binding site [ion binding]; other site
697329002419	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329002420	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329002421	non-specific DNA binding site [nucleotide binding]; other site
697329002422	salt bridge; other site
697329002423	sequence-specific DNA binding site [nucleotide binding]; other site
697329002424	LytTr DNA-binding domain; Region: LytTR; smart00850
697329002425	O-Antigen ligase; Region: Wzy_C; pfam04932
697329002426	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
697329002427	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
697329002428	protein-export membrane protein SecD; Region: secD; TIGR01129
697329002429	Protein export membrane protein; Region: SecD_SecF; cl14618
697329002430	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
697329002431	Protein export membrane protein; Region: SecD_SecF; cl14618
697329002432	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
697329002433	Peptidase family M23; Region: Peptidase_M23; pfam01551
697329002434	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
697329002435	NAD-dependent deacetylase; Provisional; Region: PRK00481
697329002436	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
697329002437	CAAX protease self-immunity; Region: Abi; pfam02517
697329002438	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
697329002439	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
697329002440	putative metal binding site [ion binding]; other site
697329002441	Predicted integral membrane protein [Function unknown]; Region: COG5542
697329002442	4-hydroxy-2-oxovalerate aldolase-like, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA_like; cd07944
697329002443	active site
697329002444	catalytic residues [active]
697329002445	metal binding site [ion binding]; metal-binding site
697329002446	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
697329002447	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
697329002448	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329002449	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
697329002450	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
697329002451	active site
697329002452	dimer interface [polypeptide binding]; other site
697329002453	metal binding site [ion binding]; metal-binding site
697329002454	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
697329002455	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
697329002456	hinge; other site
697329002457	active site
697329002458	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
697329002459	nudix motif; other site
697329002460	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
697329002461	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
697329002462	Tetramer interface [polypeptide binding]; other site
697329002463	active site
697329002464	FMN-binding site [chemical binding]; other site
697329002465	Domain of unknown function (DUF4364); Region: DUF4364; pfam14277
697329002466	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329002467	Interdomain contacts; other site
697329002468	Cytokine receptor motif; other site
697329002469	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
697329002470	active site
697329002471	catalytic triad [active]
697329002472	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
697329002473	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
697329002474	inhibitor-cofactor binding pocket; inhibition site
697329002475	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329002476	catalytic residue [active]
697329002477	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
697329002478	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
697329002479	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
697329002480	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
697329002481	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
697329002482	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329002483	active site
697329002484	RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526
697329002485	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
697329002486	Ligand binding site; other site
697329002487	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
697329002488	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
697329002489	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
697329002490	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
697329002491	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
697329002492	4Fe-4S binding domain; Region: Fer4; pfam00037
697329002493	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; Region: FrhB_FdhB_C; pfam04432
697329002494	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
697329002495	Bacterial sugar transferase; Region: Bac_transf; pfam02397
697329002496	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
697329002497	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329002498	active site
697329002499	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
697329002500	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
697329002501	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
697329002502	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_4; cd03795
697329002503	putative ADP-binding pocket [chemical binding]; other site
697329002504	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
697329002505	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
697329002506	substrate binding site; other site
697329002507	tetramer interface; other site
697329002508	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
697329002509	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
697329002510	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
697329002511	NAD binding site [chemical binding]; other site
697329002512	substrate binding site [chemical binding]; other site
697329002513	homodimer interface [polypeptide binding]; other site
697329002514	active site
697329002515	Acyltransferase family; Region: Acyl_transf_3; pfam01757
697329002516	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
697329002517	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
697329002518	NADP binding site [chemical binding]; other site
697329002519	active site
697329002520	putative substrate binding site [chemical binding]; other site
697329002521	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
697329002522	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
697329002523	putative NAD(P) binding site [chemical binding]; other site
697329002524	active site
697329002525	putative substrate binding site [chemical binding]; other site
697329002526	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
697329002527	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
697329002528	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
697329002529	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
697329002530	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
697329002531	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
697329002532	active site
697329002533	catalytic tetrad [active]
697329002534	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2739; cl17893
697329002535	signal recognition particle protein; Provisional; Region: PRK10867
697329002536	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
697329002537	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
697329002538	P loop; other site
697329002539	GTP binding site [chemical binding]; other site
697329002540	Signal peptide binding domain; Region: SRP_SPB; pfam02978
697329002541	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
697329002542	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
697329002543	KH domain; Region: KH_4; pfam13083
697329002544	Transcriptional regulator; Region: Rrf2; cl17282
697329002545	Rrf2 family protein; Region: rrf2_super; TIGR00738
697329002546	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
697329002547	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
697329002548	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u1; cd12826
697329002549	Cl binding site [ion binding]; other site
697329002550	oligomer interface [polypeptide binding]; other site
697329002551	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
697329002552	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
697329002553	Domain of unknown function DUF21; Region: DUF21; pfam01595
697329002554	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
697329002555	Transporter associated domain; Region: CorC_HlyC; pfam03471
697329002556	Transglutaminase/protease-like homologues; Region: TGc; smart00460
697329002557	Predicted membrane protein [Function unknown]; Region: COG3601
697329002558	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
697329002559	elongation factor P; Validated; Region: PRK00529
697329002560	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
697329002561	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
697329002562	RNA binding site [nucleotide binding]; other site
697329002563	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
697329002564	RNA binding site [nucleotide binding]; other site
697329002565	6-phosphofructokinase; Provisional; Region: PRK14072
697329002566	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
697329002567	active site
697329002568	ADP/pyrophosphate binding site [chemical binding]; other site
697329002569	dimerization interface [polypeptide binding]; other site
697329002570	allosteric effector site; other site
697329002571	fructose-1,6-bisphosphate binding site; other site
697329002572	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
697329002573	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
697329002574	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
697329002575	Ligand binding site; other site
697329002576	Putative Catalytic site; other site
697329002577	DXD motif; other site
697329002578	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
697329002579	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
697329002580	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; Region: Octopine_DH; pfam02317
697329002581	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
697329002582	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
697329002583	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
697329002584	active site
697329002585	Dehydroquinase class II; Region: DHquinase_II; pfam01220
697329002586	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
697329002587	trimer interface [polypeptide binding]; other site
697329002588	active site
697329002589	dimer interface [polypeptide binding]; other site
697329002590	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
697329002591	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
697329002592	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
697329002593	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
697329002594	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
697329002595	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
697329002596	PhoU domain; Region: PhoU; pfam01895
697329002597	PhoU domain; Region: PhoU; pfam01895
697329002598	excinuclease ABC subunit B; Provisional; Region: PRK05298
697329002599	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329002600	ATP binding site [chemical binding]; other site
697329002601	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329002602	nucleotide binding region [chemical binding]; other site
697329002603	ATP-binding site [chemical binding]; other site
697329002604	Ultra-violet resistance protein B; Region: UvrB; pfam12344
697329002605	UvrB/uvrC motif; Region: UVR; pfam02151
697329002606	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
697329002607	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
697329002608	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
697329002609	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
697329002610	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329002611	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329002612	non-specific DNA binding site [nucleotide binding]; other site
697329002613	salt bridge; other site
697329002614	sequence-specific DNA binding site [nucleotide binding]; other site
697329002615	Sporulation related domain; Region: SPOR; cl10051
697329002616	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
697329002617	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
697329002618	active site
697329002619	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
697329002620	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
697329002621	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329002622	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329002623	non-specific DNA binding site [nucleotide binding]; other site
697329002624	salt bridge; other site
697329002625	sequence-specific DNA binding site [nucleotide binding]; other site
697329002626	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
697329002627	Malic enzyme, N-terminal domain; Region: malic; pfam00390
697329002628	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
697329002629	putative NAD(P) binding site [chemical binding]; other site
697329002630	Quinolinate synthetase A protein; Region: NadA; pfam02445
697329002631	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329002632	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329002633	dimerization interface [polypeptide binding]; other site
697329002634	ligand binding site [chemical binding]; other site
697329002635	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329002636	metal binding site [ion binding]; metal-binding site
697329002637	active site
697329002638	I-site; other site
697329002639	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329002640	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329002641	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
697329002642	DNA binding site [nucleotide binding]
697329002643	domain linker motif; other site
697329002644	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329002645	dimerization interface [polypeptide binding]; other site
697329002646	ligand binding site [chemical binding]; other site
697329002647	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
697329002648	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329002649	dimer interface [polypeptide binding]; other site
697329002650	conserved gate region; other site
697329002651	putative PBP binding loops; other site
697329002652	ABC-ATPase subunit interface; other site
697329002653	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
697329002654	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329002655	dimer interface [polypeptide binding]; other site
697329002656	conserved gate region; other site
697329002657	putative PBP binding loops; other site
697329002658	ABC-ATPase subunit interface; other site
697329002659	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
697329002660	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
697329002661	Beta-Casp domain; Region: Beta-Casp; smart01027
697329002662	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
697329002663	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
697329002664	homodimer interface [polypeptide binding]; other site
697329002665	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
697329002666	active site pocket [active]
697329002667	septum site-determining protein MinD; Region: minD_bact; TIGR01968
697329002668	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
697329002669	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
697329002670	active site
697329002671	dimer interfaces [polypeptide binding]; other site
697329002672	catalytic residues [active]
697329002673	Uncharacterized conserved protein [Function unknown]; Region: COG1434
697329002674	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
697329002675	putative active site [active]
697329002676	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
697329002677	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
697329002678	dimer interface [polypeptide binding]; other site
697329002679	motif 1; other site
697329002680	active site
697329002681	motif 2; other site
697329002682	motif 3; other site
697329002683	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
697329002684	anticodon binding site; other site
697329002685	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
697329002686	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329002687	RNA binding surface [nucleotide binding]; other site
697329002688	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
697329002689	active site
697329002690	uracil binding [chemical binding]; other site
697329002691	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
697329002692	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
697329002693	Walker A/P-loop; other site
697329002694	ATP binding site [chemical binding]; other site
697329002695	Q-loop/lid; other site
697329002696	ABC transporter signature motif; other site
697329002697	Walker B; other site
697329002698	D-loop; other site
697329002699	H-loop/switch region; other site
697329002700	TOBE domain; Region: TOBE; pfam03459
697329002701	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
697329002702	Dynamin family; Region: Dynamin_N; pfam00350
697329002703	G1 box; other site
697329002704	GTP/Mg2+ binding site [chemical binding]; other site
697329002705	G2 box; other site
697329002706	Switch I region; other site
697329002707	G3 box; other site
697329002708	Switch II region; other site
697329002709	G4 box; other site
697329002710	G5 box; other site
697329002711	Peptidase family M48; Region: Peptidase_M48; cl12018
697329002712	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
697329002713	Dynamin family; Region: Dynamin_N; pfam00350
697329002714	G1 box; other site
697329002715	GTP/Mg2+ binding site [chemical binding]; other site
697329002716	G2 box; other site
697329002717	Switch I region; other site
697329002718	G3 box; other site
697329002719	Switch II region; other site
697329002720	G4 box; other site
697329002721	G5 box; other site
697329002722	CAAX protease self-immunity; Region: Abi; pfam02517
697329002723	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
697329002724	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
697329002725	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329002726	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329002727	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329002728	ligand binding site [chemical binding]; other site
697329002729	dimerization interface [polypeptide binding]; other site
697329002730	Helix-turn-helix domain; Region: HTH_18; pfam12833
697329002731	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329002732	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329002733	metal binding site [ion binding]; metal-binding site
697329002734	active site
697329002735	I-site; other site
697329002736	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329002737	putative metal binding site [ion binding]; other site
697329002738	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329002739	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329002740	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329002741	ligand binding site [chemical binding]; other site
697329002742	dimerization interface [polypeptide binding]; other site
697329002743	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329002744	metal binding site [ion binding]; metal-binding site
697329002745	active site
697329002746	I-site; other site
697329002747	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329002748	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329002749	Glycosyl hydrolase family 98; Region: Glyco_hydro_98M; pfam08306
697329002750	Glycosyl hydrolase family 98 C-terminal domain; Region: Glyco_hydro_98C; pfam08307
697329002751	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
697329002752	putative metal binding site [ion binding]; other site
697329002753	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
697329002754	active site
697329002755	catalytic triad [active]
697329002756	oxyanion hole [active]
697329002757	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
697329002758	Carbohydrate Binding Module family 35 (CBM35), pectate lyase-like; appended mainly to enzymes that bind mannan (Man), xylan, glucuronic acid (GlcA) and possibly glucans; Region: CBM35_pectate_lyase-like; cd04082
697329002759	Ca binding site [ion binding]; other site
697329002760	Ca binding site (active) [ion binding]; other site
697329002761	ligand binding site [chemical binding]; other site
697329002762	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
697329002763	active site
697329002764	catalytic triad [active]
697329002765	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
697329002766	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
697329002767	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
697329002768	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
697329002769	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
697329002770	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
697329002771	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
697329002772	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
697329002773	Transposase [DNA replication, recombination, and repair]; Region: COG5433
697329002774	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
697329002775	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
697329002776	PYR/PP interface [polypeptide binding]; other site
697329002777	dimer interface [polypeptide binding]; other site
697329002778	TPP binding site [chemical binding]; other site
697329002779	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
697329002780	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
697329002781	TPP-binding site [chemical binding]; other site
697329002782	dimer interface [polypeptide binding]; other site
697329002783	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
697329002784	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
697329002785	putative valine binding site [chemical binding]; other site
697329002786	dimer interface [polypeptide binding]; other site
697329002787	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
697329002788	ketol-acid reductoisomerase; Provisional; Region: PRK05479
697329002789	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
697329002790	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
697329002791	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329002792	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329002793	metal binding site [ion binding]; metal-binding site
697329002794	active site
697329002795	I-site; other site
697329002796	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
697329002797	Protein phosphatase 2C; Region: PP2C; pfam00481
697329002798	active site
697329002799	T surface-antigen of pili; Region: FctA; pfam12892
697329002800	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
697329002801	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
697329002802	T surface-antigen of pili; Region: FctA; cl16948
697329002803	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
697329002804	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329002805	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329002806	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329002807	non-specific DNA binding site [nucleotide binding]; other site
697329002808	salt bridge; other site
697329002809	sequence-specific DNA binding site [nucleotide binding]; other site
697329002810	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
697329002811	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329002812	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329002813	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329002814	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
697329002815	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
697329002816	ligand binding site [chemical binding]; other site
697329002817	flexible hinge region; other site
697329002818	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
697329002819	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
697329002820	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
697329002821	hybrid cluster protein; Provisional; Region: PRK05290
697329002822	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
697329002823	ACS interaction site; other site
697329002824	CODH interaction site; other site
697329002825	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
697329002826	hybrid metal cluster; other site
697329002827	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329002828	Interdomain contacts; other site
697329002829	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
697329002830	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329002831	FtsX-like permease family; Region: FtsX; pfam02687
697329002832	FtsX-like permease family; Region: FtsX; pfam02687
697329002833	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329002834	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329002835	Walker A/P-loop; other site
697329002836	ATP binding site [chemical binding]; other site
697329002837	Q-loop/lid; other site
697329002838	ABC transporter signature motif; other site
697329002839	Walker B; other site
697329002840	D-loop; other site
697329002841	H-loop/switch region; other site
697329002842	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329002843	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329002844	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
697329002845	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
697329002846	substrate binding pocket [chemical binding]; other site
697329002847	membrane-bound complex binding site; other site
697329002848	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
697329002849	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329002850	dimer interface [polypeptide binding]; other site
697329002851	conserved gate region; other site
697329002852	putative PBP binding loops; other site
697329002853	ABC-ATPase subunit interface; other site
697329002854	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329002855	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
697329002856	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329002857	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
697329002858	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329002859	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329002860	LysR substrate binding domain; Region: LysR_substrate; pfam03466
697329002861	dimerization interface [polypeptide binding]; other site
697329002862	putative transposase OrfB; Reviewed; Region: PHA02517
697329002863	HTH-like domain; Region: HTH_21; pfam13276
697329002864	Integrase core domain; Region: rve; pfam00665
697329002865	Integrase core domain; Region: rve_2; pfam13333
697329002866	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329002867	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329002868	Pleckstrin homology-like domain; Region: PH-like; cl17171
697329002869	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329002870	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
697329002871	catalytic residues [active]
697329002872	catalytic nucleophile [active]
697329002873	Presynaptic Site I dimer interface [polypeptide binding]; other site
697329002874	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
697329002875	Synaptic Flat tetramer interface [polypeptide binding]; other site
697329002876	Synaptic Site I dimer interface [polypeptide binding]; other site
697329002877	DNA binding site [nucleotide binding]
697329002878	Recombinase; Region: Recombinase; pfam07508
697329002879	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329002880	sporulation sigma factor SigK; Reviewed; Region: PRK05803
697329002881	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329002882	DNA binding residues [nucleotide binding]
697329002883	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329002884	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
697329002885	putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959
697329002886	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
697329002887	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
697329002888	G1 box; other site
697329002889	GTP/Mg2+ binding site [chemical binding]; other site
697329002890	Switch I region; other site
697329002891	G2 box; other site
697329002892	Switch II region; other site
697329002893	G3 box; other site
697329002894	G4 box; other site
697329002895	G5 box; other site
697329002896	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Region: rSAM_HydE; TIGR03956
697329002897	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329002898	FeS/SAM binding site; other site
697329002899	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
697329002900	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
697329002901	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329002902	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
697329002903	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329002904	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
697329002905	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; Region: Fer4_NifH; pfam00142
697329002906	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329002907	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329002908	Acylphosphatase; Region: Acylphosphatase; pfam00708
697329002909	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
697329002910	HypF finger; Region: zf-HYPF; pfam07503
697329002911	HypF finger; Region: zf-HYPF; pfam07503
697329002912	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
697329002913	HupF/HypC family; Region: HupF_HypC; pfam01455
697329002914	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
697329002915	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
697329002916	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
697329002917	dimerization interface [polypeptide binding]; other site
697329002918	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
697329002919	ATP binding site [chemical binding]; other site
697329002920	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
697329002921	trimer interface [polypeptide binding]; other site
697329002922	active site
697329002923	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
697329002924	Peptidase family U32; Region: Peptidase_U32; pfam01136
697329002925	Collagenase; Region: DUF3656; pfam12392
697329002926	Peptidase family U32; Region: Peptidase_U32; cl03113
697329002927	Cell division protein ZapA; Region: ZapA; pfam05164
697329002928	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329002929	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329002930	Coenzyme A binding pocket [chemical binding]; other site
697329002931	Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_1_2; cd06113
697329002932	dimer interface [polypeptide binding]; other site
697329002933	Citrate synthase; Region: Citrate_synt; pfam00285
697329002934	active site
697329002935	citrylCoA binding site [chemical binding]; other site
697329002936	oxalacetate/citrate binding site [chemical binding]; other site
697329002937	coenzyme A binding site [chemical binding]; other site
697329002938	catalytic triad [active]
697329002939	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
697329002940	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
697329002941	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
697329002942	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329002943	von Willebrand factor type A domain; Region: VWA_2; pfam13519
697329002944	Protein of unknown function DUF45; Region: DUF45; pfam01863
697329002945	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
697329002946	Preprotein translocase SecG subunit; Region: SecG; pfam03840
697329002947	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329002948	Coenzyme A binding pocket [chemical binding]; other site
697329002949	ribonuclease R; Region: RNase_R; TIGR02063
697329002950	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
697329002951	RNB domain; Region: RNB; pfam00773
697329002952	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
697329002953	RNA binding site [nucleotide binding]; other site
697329002954	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
697329002955	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
697329002956	putative RNA binding site [nucleotide binding]; other site
697329002957	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329002958	S-adenosylmethionine binding site [chemical binding]; other site
697329002959	Iron only hydrogenase large subunit, C-terminal domain [General function prediction only]; Region: COG4624
697329002960	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
697329002961	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
697329002962	putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959
697329002963	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
697329002964	Putative Sin3 binding protein; Region: Stb3; pfam10330
697329002965	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329002966	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
697329002967	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
697329002968	active site
697329002969	ATP binding site [chemical binding]; other site
697329002970	substrate binding site [chemical binding]; other site
697329002971	activation loop (A-loop); other site
697329002972	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
697329002973	metal ion-dependent adhesion site (MIDAS); other site
697329002974	Protein phosphatase 2C; Region: PP2C_2; pfam13672
697329002975	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329002976	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329002977	metal binding site [ion binding]; metal-binding site
697329002978	active site
697329002979	I-site; other site
697329002980	Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Region: Endoglucanase_E_like; cd01831
697329002981	active site
697329002982	catalytic triad [active]
697329002983	oxyanion hole [active]
697329002984	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
697329002985	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
697329002986	Substrate binding site; other site
697329002987	Mg++ binding site; other site
697329002988	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
697329002989	active site
697329002990	substrate binding site [chemical binding]; other site
697329002991	CoA binding site [chemical binding]; other site
697329002992	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329002993	DNA-binding site [nucleotide binding]; DNA binding site
697329002994	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329002995	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329002996	Walker A/P-loop; other site
697329002997	ATP binding site [chemical binding]; other site
697329002998	Q-loop/lid; other site
697329002999	ABC transporter signature motif; other site
697329003000	Walker B; other site
697329003001	D-loop; other site
697329003002	H-loop/switch region; other site
697329003003	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
697329003004	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
697329003005	Na binding site [ion binding]; other site
697329003006	Melibiase; Region: Melibiase; pfam02065
697329003007	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
697329003008	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
697329003009	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329003010	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329003011	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
697329003012	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329003013	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329003014	active site
697329003015	phosphorylation site [posttranslational modification]
697329003016	intermolecular recognition site; other site
697329003017	dimerization interface [polypeptide binding]; other site
697329003018	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329003019	DNA binding site [nucleotide binding]
697329003020	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329003021	HAMP domain; Region: HAMP; pfam00672
697329003022	dimerization interface [polypeptide binding]; other site
697329003023	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329003024	dimer interface [polypeptide binding]; other site
697329003025	phosphorylation site [posttranslational modification]
697329003026	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329003027	ATP binding site [chemical binding]; other site
697329003028	Mg2+ binding site [ion binding]; other site
697329003029	G-X-G motif; other site
697329003030	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
697329003031	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
697329003032	PYR/PP interface [polypeptide binding]; other site
697329003033	dimer interface [polypeptide binding]; other site
697329003034	TPP binding site [chemical binding]; other site
697329003035	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
697329003036	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
697329003037	TPP-binding site [chemical binding]; other site
697329003038	dimer interface [polypeptide binding]; other site
697329003039	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
697329003040	TrkA-N domain; Region: TrkA_N; pfam02254
697329003041	TrkA-C domain; Region: TrkA_C; pfam02080
697329003042	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
697329003043	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
697329003044	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
697329003045	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329003046	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329003047	metal binding site [ion binding]; metal-binding site
697329003048	active site
697329003049	I-site; other site
697329003050	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
697329003051	Part of AAA domain; Region: AAA_19; pfam13245
697329003052	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
697329003053	AAA domain; Region: AAA_12; pfam13087
697329003054	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
697329003055	putative active site [active]
697329003056	Protein of unknown function (DUF3320); Region: DUF3320; pfam11784
697329003057	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
697329003058	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
697329003059	Catalytic site [active]
697329003060	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
697329003061	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
697329003062	membrane-bound complex binding site; other site
697329003063	hinge residues; other site
697329003064	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
697329003065	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
697329003066	substrate binding pocket [chemical binding]; other site
697329003067	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329003068	dimer interface [polypeptide binding]; other site
697329003069	conserved gate region; other site
697329003070	putative PBP binding loops; other site
697329003071	ABC-ATPase subunit interface; other site
697329003072	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
697329003073	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
697329003074	Walker A/P-loop; other site
697329003075	ATP binding site [chemical binding]; other site
697329003076	Q-loop/lid; other site
697329003077	ABC transporter signature motif; other site
697329003078	Walker B; other site
697329003079	D-loop; other site
697329003080	H-loop/switch region; other site
697329003081	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
697329003082	catalytic residues [active]
697329003083	dimer interface [polypeptide binding]; other site
697329003084	putative heme d1 biosynthesis radical SAM protein NirJ2; Region: rSAM_NirJ2; TIGR04055
697329003085	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329003086	FeS/SAM binding site; other site
697329003087	Uncharacterized BCR, COG1636; Region: DUF208; pfam02677
697329003088	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329003089	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329003090	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329003091	Walker A/P-loop; other site
697329003092	ATP binding site [chemical binding]; other site
697329003093	Q-loop/lid; other site
697329003094	ABC transporter signature motif; other site
697329003095	Walker B; other site
697329003096	D-loop; other site
697329003097	H-loop/switch region; other site
697329003098	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329003099	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329003100	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
697329003101	Walker A/P-loop; other site
697329003102	ATP binding site [chemical binding]; other site
697329003103	Q-loop/lid; other site
697329003104	ABC transporter signature motif; other site
697329003105	Walker B; other site
697329003106	D-loop; other site
697329003107	H-loop/switch region; other site
697329003108	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
697329003109	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
697329003110	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
697329003111	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
697329003112	Malonate decarboxylase gamma subunit (MdcE); Region: MdcE; cl17835
697329003113	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
697329003114	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
697329003115	carboxyltransferase (CT) interaction site; other site
697329003116	biotinylation site [posttranslational modification]; other site
697329003117	oxaloacetate decarboxylase; Provisional; Region: PRK12331
697329003118	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
697329003119	active site
697329003120	catalytic residues [active]
697329003121	metal binding site [ion binding]; metal-binding site
697329003122	homodimer binding site [polypeptide binding]; other site
697329003123	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
697329003124	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
697329003125	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
697329003126	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329003127	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329003128	non-specific DNA binding site [nucleotide binding]; other site
697329003129	salt bridge; other site
697329003130	sequence-specific DNA binding site [nucleotide binding]; other site
697329003131	dipicolinate synthase subunit A; Reviewed; Region: PRK08306
697329003132	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
697329003133	dipicolinate synthase subunit B; Reviewed; Region: spoVFB; PRK08305
697329003134	AAA domain; Region: AAA_28; pfam13521
697329003135	Predicted ATPase [General function prediction only]; Region: COG3911
697329003136	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cl11964
697329003137	putative active site; other site
697329003138	putative metal binding residues [ion binding]; other site
697329003139	signature motif; other site
697329003140	putative triphosphate binding site [ion binding]; other site
697329003141	GXGXG domain. This domain of unknown function is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS),  in subunit C of tungsten formylmethanofuran dehydrogenase (FwdC) and in subunit C of molybdenum formylmethanofuran...; Region: GXGXG; cl00239
697329003142	domain_subunit interface; other site
697329003143	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
697329003144	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
697329003145	type II secretion system protein D; Region: type_II_gspD; TIGR02517
697329003146	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
697329003147	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
697329003148	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
697329003149	GGGtGRT protein; Region: GGGtGRT; pfam14057
697329003150	AAA domain; Region: AAA_13; pfam13166
697329003151	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
697329003152	binding surface
697329003153	TPR motif; other site
697329003154	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
697329003155	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
697329003156	binding surface
697329003157	TPR motif; other site
697329003158	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
697329003159	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
697329003160	Catalytic domain of Protein Kinases; Region: PKc; cd00180
697329003161	active site
697329003162	ATP binding site [chemical binding]; other site
697329003163	substrate binding site [chemical binding]; other site
697329003164	activation loop (A-loop); other site
697329003165	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
697329003166	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
697329003167	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
697329003168	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329003169	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
697329003170	DNA binding site [nucleotide binding]
697329003171	domain linker motif; other site
697329003172	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
697329003173	dimerization interface [polypeptide binding]; other site
697329003174	ligand binding site [chemical binding]; other site
697329003175	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
697329003176	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
697329003177	putative substrate binding site [chemical binding]; other site
697329003178	putative ATP binding site [chemical binding]; other site
697329003179	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
697329003180	dimerization domain swap beta strand [polypeptide binding]; other site
697329003181	regulatory protein interface [polypeptide binding]; other site
697329003182	active site
697329003183	regulatory phosphorylation site [posttranslational modification]; other site
697329003184	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
697329003185	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
697329003186	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
697329003187	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
697329003188	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329003189	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329003190	Int/Topo IB signature motif; other site
697329003191	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
697329003192	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329003193	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
697329003194	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
697329003195	DpnII restriction endonuclease; Region: DpnII; pfam04556
697329003196	AIPR protein; Region: AIPR; pfam10592
697329003197	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329003198	S-adenosylmethionine binding site [chemical binding]; other site
697329003199	DNA methylase; Region: N6_N4_Mtase; cl17433
697329003200	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329003201	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329003202	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329003203	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329003204	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329003205	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329003206	Int/Topo IB signature motif; other site
697329003207	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
697329003208	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329003209	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
697329003210	Transposase domain (DUF772); Region: DUF772; pfam05598
697329003211	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
697329003212	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
697329003213	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
697329003214	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329003215	S-adenosylmethionine binding site [chemical binding]; other site
697329003216	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329003217	AAA domain; Region: AAA_13; pfam13166
697329003218	Walker A/P-loop; other site
697329003219	ATP binding site [chemical binding]; other site
697329003220	Uncharacterized conserved protein [Function unknown]; Region: COG4127
697329003221	Restriction endonuclease; Region: Mrr_cat; pfam04471
697329003222	AAA ATPase domain; Region: AAA_15; pfam13175
697329003223	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329003224	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329003225	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329003226	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329003227	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329003228	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329003229	Int/Topo IB signature motif; other site
697329003230	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329003231	Helix-turn-helix domain; Region: HTH_17; cl17695
697329003232	AAA domain; Region: AAA_25; pfam13481
697329003233	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
697329003234	Walker A motif; other site
697329003235	ATP binding site [chemical binding]; other site
697329003236	Walker B motif; other site
697329003237	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
697329003238	generic binding surface II; other site
697329003239	generic binding surface I; other site
697329003240	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
697329003241	ATP binding site [chemical binding]; other site
697329003242	Mg2+ binding site [ion binding]; other site
697329003243	G-X-G motif; other site
697329003244	Z1 domain; Region: Z1; pfam10593
697329003245	Domain of unknown function (DUF4420); Region: DUF4420; pfam14390
697329003246	AIPR protein; Region: AIPR; pfam10592
697329003247	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
697329003248	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
697329003249	cofactor binding site; other site
697329003250	DNA binding site [nucleotide binding]
697329003251	substrate interaction site [chemical binding]; other site
697329003252	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
697329003253	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
697329003254	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
697329003255	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
697329003256	additional DNA contacts [nucleotide binding]; other site
697329003257	mismatch recognition site; other site
697329003258	active site
697329003259	zinc binding site [ion binding]; other site
697329003260	DNA intercalation site [nucleotide binding]; other site
697329003261	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329003262	non-specific DNA binding site [nucleotide binding]; other site
697329003263	salt bridge; other site
697329003264	sequence-specific DNA binding site [nucleotide binding]; other site
697329003265	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
697329003266	AAA domain; Region: AAA_14; pfam13173
697329003267	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329003268	AMP binding site [chemical binding]; other site
697329003269	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
697329003270	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
697329003271	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
697329003272	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
697329003273	Protein of unknown function (DUF3791); Region: DUF3791; pfam12668
697329003274	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
697329003275	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
697329003276	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329003277	Zn2+ binding site [ion binding]; other site
697329003278	Mg2+ binding site [ion binding]; other site
697329003279	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
697329003280	AAA domain; Region: AAA_14; pfam13173
697329003281	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003282	transcriptional antiterminator BglG; Provisional; Region: PRK09772
697329003283	CAT RNA binding domain; Region: CAT_RBD; smart01061
697329003284	PRD domain; Region: PRD; pfam00874
697329003285	PRD domain; Region: PRD; pfam00874
697329003286	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
697329003287	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
697329003288	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
697329003289	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
697329003290	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
697329003291	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329003292	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329003293	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
697329003294	dimerization interface [polypeptide binding]; other site
697329003295	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003296	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329003297	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329003298	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003299	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329003300	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329003301	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329003302	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329003303	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329003304	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329003305	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
697329003306	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
697329003307	AAA domain; Region: AAA_14; pfam13173
697329003308	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329003309	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329003310	Coenzyme A binding pocket [chemical binding]; other site
697329003311	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
697329003312	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329003313	Uncharacterized ArCR, COG2043; Region: DUF169; cl00894
697329003314	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
697329003315	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
697329003316	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329003317	Walker A motif; other site
697329003318	ATP binding site [chemical binding]; other site
697329003319	Walker B motif; other site
697329003320	arginine finger; other site
697329003321	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329003322	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
697329003323	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
697329003324	Bacterial SH3 domain; Region: SH3_3; cl17532
697329003325	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003326	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003327	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003328	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003329	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
697329003330	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329003331	Radical SAM superfamily; Region: Radical_SAM; pfam04055
697329003332	Transposase, Mutator family; Region: Transposase_mut; pfam00872
697329003333	MULE transposase domain; Region: MULE; pfam10551
697329003334	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329003335	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329003336	Transposase IS200 like; Region: Y1_Tnp; pfam01797
697329003337	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
697329003338	metal ion-dependent adhesion site (MIDAS); other site
697329003339	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
697329003340	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
697329003341	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
697329003342	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
697329003343	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
697329003344	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
697329003345	active site
697329003346	catalytic tetrad [active]
697329003347	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
697329003348	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
697329003349	active site
697329003350	catalytic tetrad [active]
697329003351	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329003352	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329003353	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
697329003354	G3 box; other site
697329003355	Switch II region; other site
697329003356	G4 box; other site
697329003357	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
697329003358	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
697329003359	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329003360	Walker A/P-loop; other site
697329003361	ATP binding site [chemical binding]; other site
697329003362	Q-loop/lid; other site
697329003363	ABC transporter signature motif; other site
697329003364	Walker B; other site
697329003365	D-loop; other site
697329003366	H-loop/switch region; other site
697329003367	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329003368	DNA-binding site [nucleotide binding]; DNA binding site
697329003369	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
697329003370	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
697329003371	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
697329003372	active site
697329003373	substrate binding site [chemical binding]; other site
697329003374	trimer interface [polypeptide binding]; other site
697329003375	CoA binding site [chemical binding]; other site
697329003376	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329003377	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
697329003378	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
697329003379	active site
697329003380	catalytic tetrad [active]
697329003381	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
697329003382	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
697329003383	EamA-like transporter family; Region: EamA; pfam00892
697329003384	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
697329003385	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329003386	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
697329003387	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329003388	active site
697329003389	phosphorylation site [posttranslational modification]
697329003390	intermolecular recognition site; other site
697329003391	dimerization interface [polypeptide binding]; other site
697329003392	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
697329003393	DNA binding residues [nucleotide binding]
697329003394	dimerization interface [polypeptide binding]; other site
697329003395	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
697329003396	Histidine kinase; Region: HisKA_3; pfam07730
697329003397	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
697329003398	ATP binding site [chemical binding]; other site
697329003399	Mg2+ binding site [ion binding]; other site
697329003400	G-X-G motif; other site
697329003401	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329003402	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329003403	Walker A/P-loop; other site
697329003404	ATP binding site [chemical binding]; other site
697329003405	Q-loop/lid; other site
697329003406	ABC transporter signature motif; other site
697329003407	Walker B; other site
697329003408	D-loop; other site
697329003409	H-loop/switch region; other site
697329003410	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
697329003411	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
697329003412	ABC-2 type transporter; Region: ABC2_membrane; cl17235
697329003413	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003414	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003415	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329003416	Interdomain contacts; other site
697329003417	Cytokine receptor motif; other site
697329003418	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
697329003419	EF-hand domain pair; Region: EF_hand_5; pfam13499
697329003420	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329003421	Coenzyme A binding pocket [chemical binding]; other site
697329003422	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329003423	S-adenosylmethionine binding site [chemical binding]; other site
697329003424	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
697329003425	Bacterial SH3 domain; Region: SH3_3; cl17532
697329003426	Bacterial sugar transferase; Region: Bac_transf; pfam02397
697329003427	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329003428	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
697329003429	active site
697329003430	nucleotide binding site [chemical binding]; other site
697329003431	HIGH motif; other site
697329003432	KMSKS motif; other site
697329003433	Ferredoxin [Energy production and conversion]; Region: NapF; COG1145
697329003434	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329003435	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329003436	metal binding site [ion binding]; metal-binding site
697329003437	active site
697329003438	I-site; other site
697329003439	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329003440	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329003441	active site
697329003442	phosphorylation site [posttranslational modification]
697329003443	intermolecular recognition site; other site
697329003444	dimerization interface [polypeptide binding]; other site
697329003445	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329003446	DNA binding site [nucleotide binding]
697329003447	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329003448	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329003449	Walker A/P-loop; other site
697329003450	ATP binding site [chemical binding]; other site
697329003451	Q-loop/lid; other site
697329003452	ABC transporter signature motif; other site
697329003453	Walker B; other site
697329003454	D-loop; other site
697329003455	H-loop/switch region; other site
697329003456	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
697329003457	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
697329003458	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329003459	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329003460	dimer interface [polypeptide binding]; other site
697329003461	phosphorylation site [posttranslational modification]
697329003462	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329003463	ATP binding site [chemical binding]; other site
697329003464	Mg2+ binding site [ion binding]; other site
697329003465	G-X-G motif; other site
697329003466	HD supefamily hydrolase [General function prediction only]; Region: COG3294
697329003467	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
697329003468	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329003469	Walker A motif; other site
697329003470	ATP binding site [chemical binding]; other site
697329003471	Walker B motif; other site
697329003472	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
697329003473	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329003474	active site
697329003475	DNA binding site [nucleotide binding]
697329003476	Int/Topo IB signature motif; other site
697329003477	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329003478	active site
697329003479	DNA binding site [nucleotide binding]
697329003480	Int/Topo IB signature motif; other site
697329003481	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329003482	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329003483	active site
697329003484	DNA binding site [nucleotide binding]
697329003485	Int/Topo IB signature motif; other site
697329003486	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
697329003487	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
697329003488	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329003489	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329003490	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329003491	dimerization interface [polypeptide binding]; other site
697329003492	ligand binding site [chemical binding]; other site
697329003493	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329003494	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329003495	metal binding site [ion binding]; metal-binding site
697329003496	active site
697329003497	I-site; other site
697329003498	Glycosyl hydrolase family 43; Region: GH43_AXH_1; cd09003
697329003499	substrate binding site [chemical binding]; other site
697329003500	active site
697329003501	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
697329003502	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
697329003503	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329003504	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329003505	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329003506	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
697329003507	Ubiquitin homologues; Region: UBQ; smart00213
697329003508	Ubiquitin; Region: Ubiquitin; cd01803
697329003509	Ubq - CUE interaction site; other site
697329003510	Ubq - E2 interaction site; other site
697329003511	Ubq - UCH interaction site; other site
697329003512	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
697329003513	active site
697329003514	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
697329003515	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329003516	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329003517	DNA binding residues [nucleotide binding]
697329003518	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329003519	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329003520	Sugar fermentation stimulation protein; Region: SfsA; cl00647
697329003521	Cupin domain; Region: Cupin_2; pfam07883
697329003522	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
697329003523	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329003524	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329003525	non-specific DNA binding site [nucleotide binding]; other site
697329003526	salt bridge; other site
697329003527	sequence-specific DNA binding site [nucleotide binding]; other site
697329003528	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
697329003529	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329003530	putative metal binding site [ion binding]; other site
697329003531	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329003532	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
697329003533	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329003534	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329003535	Walker A/P-loop; other site
697329003536	ATP binding site [chemical binding]; other site
697329003537	Q-loop/lid; other site
697329003538	ABC transporter signature motif; other site
697329003539	Walker B; other site
697329003540	D-loop; other site
697329003541	H-loop/switch region; other site
697329003542	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
697329003543	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
697329003544	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
697329003545	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
697329003546	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
697329003547	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
697329003548	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
697329003549	acyl-activating enzyme (AAE) consensus motif; other site
697329003550	active site
697329003551	AMP binding site [chemical binding]; other site
697329003552	substrate binding site [chemical binding]; other site
697329003553	Phosphopantetheine attachment site; Region: PP-binding; cl09936
697329003554	Condensation domain; Region: Condensation; pfam00668
697329003555	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
697329003556	Nonribosomal peptide synthase; Region: NRPS; pfam08415
697329003557	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
697329003558	acyl-activating enzyme (AAE) consensus motif; other site
697329003559	AMP binding site [chemical binding]; other site
697329003560	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003561	Condensation domain; Region: Condensation; pfam00668
697329003562	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
697329003563	Nonribosomal peptide synthase; Region: NRPS; pfam08415
697329003564	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
697329003565	acyl-activating enzyme (AAE) consensus motif; other site
697329003566	AMP binding site [chemical binding]; other site
697329003567	Methyltransferase domain; Region: Methyltransf_12; pfam08242
697329003568	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329003569	CoA binding site [chemical binding]; other site
697329003570	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003571	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; cl09823
697329003572	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
697329003573	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
697329003574	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
697329003575	Walker A/P-loop; other site
697329003576	ATP binding site [chemical binding]; other site
697329003577	Q-loop/lid; other site
697329003578	ABC transporter signature motif; other site
697329003579	Walker B; other site
697329003580	D-loop; other site
697329003581	H-loop/switch region; other site
697329003582	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
697329003583	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329003584	Walker A/P-loop; other site
697329003585	ATP binding site [chemical binding]; other site
697329003586	Q-loop/lid; other site
697329003587	ABC transporter signature motif; other site
697329003588	Walker B; other site
697329003589	D-loop; other site
697329003590	H-loop/switch region; other site
697329003591	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
697329003592	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
697329003593	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
697329003594	active site
697329003595	Methyltransferase domain; Region: Methyltransf_31; pfam13847
697329003596	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329003597	S-adenosylmethionine binding site [chemical binding]; other site
697329003598	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003599	Condensation domain; Region: Condensation; pfam00668
697329003600	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
697329003601	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
697329003602	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003603	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
697329003604	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
697329003605	active site
697329003606	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003607	Condensation domain; Region: Condensation; pfam00668
697329003608	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
697329003609	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
697329003610	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
697329003611	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329003612	Methyltransferase domain; Region: Methyltransf_31; pfam13847
697329003613	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329003614	S-adenosylmethionine binding site [chemical binding]; other site
697329003615	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329003616	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
697329003617	acyl-activating enzyme (AAE) consensus motif; other site
697329003618	acyl-activating enzyme (AAE) consensus motif; other site
697329003619	AMP binding site [chemical binding]; other site
697329003620	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003621	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003622	Condensation domain; Region: Condensation; pfam00668
697329003623	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
697329003624	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
697329003625	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
697329003626	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
697329003627	acyl-activating enzyme (AAE) consensus motif; other site
697329003628	AMP binding site [chemical binding]; other site
697329003629	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003630	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
697329003631	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
697329003632	active site
697329003633	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
697329003634	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329003635	acyl-activating enzyme (AAE) consensus motif; other site
697329003636	AMP binding site [chemical binding]; other site
697329003637	active site
697329003638	CoA binding site [chemical binding]; other site
697329003639	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
697329003640	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
697329003641	putative NADP binding site [chemical binding]; other site
697329003642	active site
697329003643	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003644	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329003645	NAD(P) binding site [chemical binding]; other site
697329003646	Condensation domain; Region: Condensation; pfam00668
697329003647	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
697329003648	Nonribosomal peptide synthase; Region: NRPS; pfam08415
697329003649	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
697329003650	acyl-activating enzyme (AAE) consensus motif; other site
697329003651	AMP binding site [chemical binding]; other site
697329003652	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329003653	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
697329003654	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
697329003655	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
697329003656	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329003657	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329003658	Walker A/P-loop; other site
697329003659	ATP binding site [chemical binding]; other site
697329003660	Q-loop/lid; other site
697329003661	ABC transporter signature motif; other site
697329003662	Walker B; other site
697329003663	D-loop; other site
697329003664	H-loop/switch region; other site
697329003665	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329003666	FtsX-like permease family; Region: FtsX; pfam02687
697329003667	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329003668	FtsX-like permease family; Region: FtsX; pfam02687
697329003669	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329003670	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329003671	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
697329003672	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329003673	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329003674	non-specific DNA binding site [nucleotide binding]; other site
697329003675	salt bridge; other site
697329003676	sequence-specific DNA binding site [nucleotide binding]; other site
697329003677	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
697329003678	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
697329003679	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
697329003680	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329003681	Interdomain contacts; other site
697329003682	Cytokine receptor motif; other site
697329003683	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
697329003684	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
697329003685	ATP binding site [chemical binding]; other site
697329003686	substrate interface [chemical binding]; other site
697329003687	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
697329003688	Ligand Binding Site [chemical binding]; other site
697329003689	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
697329003690	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
697329003691	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329003692	catalytic residue [active]
697329003693	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329003694	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003695	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003696	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003697	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329003698	Interdomain contacts; other site
697329003699	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
697329003700	Cupin domain; Region: Cupin_2; pfam07883
697329003701	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329003702	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329003703	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329003704	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329003705	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
697329003706	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
697329003707	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
697329003708	DNA binding residues [nucleotide binding]
697329003709	dimer interface [polypeptide binding]; other site
697329003710	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
697329003711	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
697329003712	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
697329003713	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
697329003714	Isochorismatase family; Region: Isochorismatase; pfam00857
697329003715	catalytic triad [active]
697329003716	conserved cis-peptide bond; other site
697329003717	SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; Region: SERPIN; cl00137
697329003718	reactive center loop; other site
697329003719	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK12315
697329003720	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
697329003721	TPP-binding site; other site
697329003722	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
697329003723	PYR/PP interface [polypeptide binding]; other site
697329003724	dimer interface [polypeptide binding]; other site
697329003725	TPP binding site [chemical binding]; other site
697329003726	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
697329003727	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
697329003728	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329003729	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
697329003730	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
697329003731	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
697329003732	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329003733	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
697329003734	Coenzyme A binding pocket [chemical binding]; other site
697329003735	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
697329003736	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
697329003737	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329003738	homodimer interface [polypeptide binding]; other site
697329003739	catalytic residue [active]
697329003740	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
697329003741	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
697329003742	active site
697329003743	HIGH motif; other site
697329003744	dimer interface [polypeptide binding]; other site
697329003745	KMSKS motif; other site
697329003746	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13633
697329003747	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
697329003748	Walker A/P-loop; other site
697329003749	ATP binding site [chemical binding]; other site
697329003750	Q-loop/lid; other site
697329003751	ABC transporter signature motif; other site
697329003752	Walker B; other site
697329003753	D-loop; other site
697329003754	H-loop/switch region; other site
697329003755	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13637
697329003756	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
697329003757	Walker A/P-loop; other site
697329003758	ATP binding site [chemical binding]; other site
697329003759	Q-loop/lid; other site
697329003760	ABC transporter signature motif; other site
697329003761	Walker B; other site
697329003762	D-loop; other site
697329003763	H-loop/switch region; other site
697329003764	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
697329003765	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
697329003766	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
697329003767	dimerization interface 3.5A [polypeptide binding]; other site
697329003768	active site
697329003769	Colicin V production protein; Region: Colicin_V; pfam02674
697329003770	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329003771	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
697329003772	Walker A motif; other site
697329003773	ATP binding site [chemical binding]; other site
697329003774	Walker B motif; other site
697329003775	arginine finger; other site
697329003776	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329003777	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
697329003778	Walker A motif; other site
697329003779	ATP binding site [chemical binding]; other site
697329003780	Walker B motif; other site
697329003781	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
697329003782	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329003783	DNA-binding site [nucleotide binding]; DNA binding site
697329003784	Predicted transcriptional regulators [Transcription]; Region: COG1725
697329003785	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329003786	DNA-binding site [nucleotide binding]; DNA binding site
697329003787	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329003788	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329003789	Walker A/P-loop; other site
697329003790	ATP binding site [chemical binding]; other site
697329003791	Q-loop/lid; other site
697329003792	ABC transporter signature motif; other site
697329003793	Walker B; other site
697329003794	D-loop; other site
697329003795	H-loop/switch region; other site
697329003796	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
697329003797	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
697329003798	Acylphosphatase; Region: Acylphosphatase; pfam00708
697329003799	Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028
697329003800	active site
697329003801	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003802	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329003803	A new structural DNA glycosylase; Region: AlkD_like; cd06561
697329003804	active site
697329003805	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
697329003806	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329003807	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329003808	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_human_like; cd03428
697329003809	active site
697329003810	Ap4A binding cleft/pocket [chemical binding]; other site
697329003811	P4 phosphate binding site; other site
697329003812	nudix motif; other site
697329003813	putative P2/P3 phosphate binding site [ion binding]; other site
697329003814	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
697329003815	SmpB-tmRNA interface; other site
697329003816	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
697329003817	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
697329003818	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
697329003819	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
697329003820	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
697329003821	putative metal binding site [ion binding]; other site
697329003822	Alanine-glyoxylate amino-transferase; Region: Aminotran_MocR; pfam12897
697329003823	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
697329003824	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329003825	catalytic residue [active]
697329003826	TSCPD domain; Region: TSCPD; cl14834
697329003827	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
697329003828	active site
697329003829	catalytic triad [active]
697329003830	oxyanion hole [active]
697329003831	Arsenate reductase and related proteins, glutaredoxin family [Inorganic ion transport and metabolism]; Region: ArsC; COG1393
697329003832	Domain of unknown function (DUF378); Region: DUF378; pfam04070
697329003833	EF-hand domain pair; Region: EF_hand_5; pfam13499
697329003834	Peptidase_C39 like family; Region: Peptidase_C39_2; pfam13529
697329003835	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
697329003836	putative active site [active]
697329003837	DNA directed RNA polymerase, 7 kDa subunit; Region: DNA_RNApol_7kD; cl00874
697329003838	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
697329003839	IHF - DNA interface [nucleotide binding]; other site
697329003840	IHF dimer interface [polypeptide binding]; other site
697329003841	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
697329003842	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
697329003843	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980
697329003844	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329003845	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
697329003846	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329003847	DNA binding residues [nucleotide binding]
697329003848	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
697329003849	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329003850	ATP binding site [chemical binding]; other site
697329003851	Mg2+ binding site [ion binding]; other site
697329003852	G-X-G motif; other site
697329003853	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
697329003854	anti sigma factor interaction site; other site
697329003855	regulatory phosphorylation site [posttranslational modification]; other site
697329003856	Spore coat associated protein JA (CotJA); Region: CotJA; pfam11007
697329003857	CotJB protein; Region: CotJB; pfam12652
697329003858	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
697329003859	Uncharacterized conserved protein [Function unknown]; Region: COG1633
697329003860	dimanganese center [ion binding]; other site
697329003861	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
697329003862	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329003863	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329003864	dimer interface [polypeptide binding]; other site
697329003865	phosphorylation site [posttranslational modification]
697329003866	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329003867	ATP binding site [chemical binding]; other site
697329003868	Mg2+ binding site [ion binding]; other site
697329003869	G-X-G motif; other site
697329003870	Response regulator receiver domain; Region: Response_reg; pfam00072
697329003871	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329003872	active site
697329003873	phosphorylation site [posttranslational modification]
697329003874	intermolecular recognition site; other site
697329003875	dimerization interface [polypeptide binding]; other site
697329003876	Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]; Region: COG3437
697329003877	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329003878	active site
697329003879	phosphorylation site [posttranslational modification]
697329003880	intermolecular recognition site; other site
697329003881	dimerization interface [polypeptide binding]; other site
697329003882	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329003883	Zn2+ binding site [ion binding]; other site
697329003884	Mg2+ binding site [ion binding]; other site
697329003885	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
697329003886	putative binding surface; other site
697329003887	active site
697329003888	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
697329003889	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
697329003890	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
697329003891	ABC transporter; Region: ABC_tran_2; pfam12848
697329003892	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
697329003893	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329003894	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329003895	Coenzyme A binding pocket [chemical binding]; other site
697329003896	Conserved hypothetical protein (DUF2461); Region: DUF2461; cl02374
697329003897	Flavodoxin domain; Region: Flavodoxin_5; cl17428
697329003898	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
697329003899	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
697329003900	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
697329003901	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329003902	motif II; other site
697329003903	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
697329003904	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
697329003905	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
697329003906	active site
697329003907	catalytic site [active]
697329003908	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
697329003909	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329003910	active site
697329003911	HIGH motif; other site
697329003912	nucleotide binding site [chemical binding]; other site
697329003913	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
697329003914	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
697329003915	active site
697329003916	KMSKS motif; other site
697329003917	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
697329003918	tRNA binding surface [nucleotide binding]; other site
697329003919	anticodon binding site; other site
697329003920	YacP-like NYN domain; Region: NYN_YacP; cl01491
697329003921	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
697329003922	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
697329003923	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329003924	active site
697329003925	HIGH motif; other site
697329003926	nucleotide binding site [chemical binding]; other site
697329003927	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
697329003928	active site
697329003929	KMSKS motif; other site
697329003930	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
697329003931	tRNA binding surface [nucleotide binding]; other site
697329003932	anticodon binding site; other site
697329003933	stage IV sporulation protein B; Region: spore_IV_B; TIGR02860
697329003934	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
697329003935	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
697329003936	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
697329003937	AAA domain; Region: AAA_18; pfam13238
697329003938	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
697329003939	FAD binding domain; Region: FAD_binding_4; pfam01565
697329003940	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
697329003941	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
697329003942	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
697329003943	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
697329003944	Hpr binding site; other site
697329003945	active site
697329003946	homohexamer subunit interaction site [polypeptide binding]; other site
697329003947	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
697329003948	Aluminium resistance protein; Region: Alum_res; pfam06838
697329003949	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
697329003950	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01710
697329003951	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
697329003952	asparagine synthetase B; Provisional; Region: asnB; PRK09431
697329003953	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
697329003954	active site
697329003955	dimer interface [polypeptide binding]; other site
697329003956	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
697329003957	Ligand Binding Site [chemical binding]; other site
697329003958	Molecular Tunnel; other site
697329003959	Response regulator receiver domain; Region: Response_reg; pfam00072
697329003960	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329003961	active site
697329003962	phosphorylation site [posttranslational modification]
697329003963	intermolecular recognition site; other site
697329003964	dimerization interface [polypeptide binding]; other site
697329003965	Helix-turn-helix domain; Region: HTH_18; pfam12833
697329003966	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329003967	glutamate dehydrogenase; Provisional; Region: PRK09414
697329003968	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
697329003969	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
697329003970	NAD(P) binding site [chemical binding]; other site
697329003971	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
697329003972	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
697329003973	ligand binding site [chemical binding]; other site
697329003974	homodimer interface [polypeptide binding]; other site
697329003975	NAD(P) binding site [chemical binding]; other site
697329003976	trimer interface B [polypeptide binding]; other site
697329003977	trimer interface A [polypeptide binding]; other site
697329003978	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
697329003979	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
697329003980	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
697329003981	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
697329003982	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
697329003983	EamA-like transporter family; Region: EamA; pfam00892
697329003984	EamA-like transporter family; Region: EamA; pfam00892
697329003985	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329003986	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329003987	metal binding site [ion binding]; metal-binding site
697329003988	active site
697329003989	I-site; other site
697329003990	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
697329003991	Flavoprotein; Region: Flavoprotein; pfam02441
697329003992	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
697329003993	Melibiase; Region: Melibiase; pfam02065
697329003994	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
697329003995	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
697329003996	active site
697329003997	NTP binding site [chemical binding]; other site
697329003998	metal binding triad [ion binding]; metal-binding site
697329003999	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
697329004000	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
697329004001	Predicted integral membrane protein [Function unknown]; Region: COG5652
697329004002	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329004003	metal binding site [ion binding]; metal-binding site
697329004004	active site
697329004005	I-site; other site
697329004006	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329004007	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329004008	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329004009	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
697329004010	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
697329004011	Walker A/P-loop; other site
697329004012	ATP binding site [chemical binding]; other site
697329004013	Q-loop/lid; other site
697329004014	ABC transporter signature motif; other site
697329004015	Walker B; other site
697329004016	D-loop; other site
697329004017	H-loop/switch region; other site
697329004018	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
697329004019	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
697329004020	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
697329004021	aminotransferase AlaT; Validated; Region: PRK09265
697329004022	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
697329004023	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329004024	homodimer interface [polypeptide binding]; other site
697329004025	catalytic residue [active]
697329004026	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
697329004027	homodimer interface [polypeptide binding]; other site
697329004028	substrate-cofactor binding pocket; other site
697329004029	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329004030	catalytic residue [active]
697329004031	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
697329004032	putative ligand binding site [chemical binding]; other site
697329004033	putative NAD binding site [chemical binding]; other site
697329004034	putative catalytic site [active]
697329004035	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329004036	glycyl-tRNA synthetase; Provisional; Region: PRK04173
697329004037	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
697329004038	motif 1; other site
697329004039	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
697329004040	active site
697329004041	motif 2; other site
697329004042	motif 3; other site
697329004043	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
697329004044	anticodon binding site; other site
697329004045	Protein of unknown function (DUF2185); Region: DUF2185; cl02019
697329004046	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
697329004047	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
697329004048	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
697329004049	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329004050	catalytic residue [active]
697329004051	Phosphoglycerate kinase; Region: PGK; pfam00162
697329004052	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
697329004053	substrate binding site [chemical binding]; other site
697329004054	hinge regions; other site
697329004055	ADP binding site [chemical binding]; other site
697329004056	catalytic site [active]
697329004057	SpoVA protein; Region: SpoVA; cl04298
697329004058	Stage V sporulation protein AD (SpoVAD); Region: SpoVAD; pfam07451
697329004059	stage V sporulation protein AD; Provisional; Region: PRK12404
697329004060	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
697329004061	nudix motif; other site
697329004062	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
697329004063	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
697329004064	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329004065	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
697329004066	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
697329004067	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
697329004068	G1 box; other site
697329004069	GTP/Mg2+ binding site [chemical binding]; other site
697329004070	Switch I region; other site
697329004071	G2 box; other site
697329004072	G3 box; other site
697329004073	Switch II region; other site
697329004074	G4 box; other site
697329004075	G5 box; other site
697329004076	Nucleoside recognition; Region: Gate; pfam07670
697329004077	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
697329004078	Nucleoside recognition; Region: Gate; pfam07670
697329004079	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
697329004080	AMP-binding enzyme; Region: AMP-binding; pfam00501
697329004081	acyl-activating enzyme (AAE) consensus motif; other site
697329004082	AMP binding site [chemical binding]; other site
697329004083	acyl carrier protein; Provisional; Region: PRK07081
697329004084	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
697329004085	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
697329004086	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
697329004087	catalytic residue [active]
697329004088	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
697329004089	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
697329004090	tartrate dehydrogenase; Region: TTC; TIGR02089
697329004091	Lamin Tail Domain; Region: LTD; pfam00932
697329004092	Fn3 associated; Region: Fn3_assoc; pfam13287
697329004093	CotH protein; Region: CotH; pfam08757
697329004094	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
697329004095	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329004096	Coenzyme A binding pocket [chemical binding]; other site
697329004097	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004098	Glycosyl hydrolase family 43; Region: GH43_AXH_1; cd09003
697329004099	substrate binding site [chemical binding]; other site
697329004100	active site
697329004101	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
697329004102	metal binding site [ion binding]; metal-binding site
697329004103	ligand binding site [chemical binding]; other site
697329004104	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
697329004105	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329004106	Walker A/P-loop; other site
697329004107	ATP binding site [chemical binding]; other site
697329004108	Q-loop/lid; other site
697329004109	ABC transporter signature motif; other site
697329004110	Walker B; other site
697329004111	D-loop; other site
697329004112	H-loop/switch region; other site
697329004113	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
697329004114	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329004115	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329004116	Interdomain contacts; other site
697329004117	Cytokine receptor motif; other site
697329004118	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329004119	Interdomain contacts; other site
697329004120	Cytokine receptor motif; other site
697329004121	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004122	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
697329004123	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329004124	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329004125	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329004126	metal binding site [ion binding]; metal-binding site
697329004127	active site
697329004128	I-site; other site
697329004129	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329004130	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
697329004131	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
697329004132	putative substrate binding site [chemical binding]; other site
697329004133	putative ATP binding site [chemical binding]; other site
697329004134	Beta-lactamase; Region: Beta-lactamase; pfam00144
697329004135	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
697329004136	alpha-galactosidase; Region: PLN02808; cl17638
697329004137	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
697329004138	ATP cone domain; Region: ATP-cone; pfam03477
697329004139	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
697329004140	EamA-like transporter family; Region: EamA; pfam00892
697329004141	EamA-like transporter family; Region: EamA; pfam00892
697329004142	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
697329004143	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
697329004144	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329004145	Zn2+ binding site [ion binding]; other site
697329004146	Mg2+ binding site [ion binding]; other site
697329004147	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
697329004148	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
697329004149	Transposase [DNA replication, recombination, and repair]; Region: COG5433
697329004150	Predicted membrane protein [Function unknown]; Region: COG1511
697329004151	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
697329004152	Methyltransferase domain; Region: Methyltransf_31; pfam13847
697329004153	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329004154	S-adenosylmethionine binding site [chemical binding]; other site
697329004155	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329004156	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329004157	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
697329004158	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
697329004159	ATP-grasp domain; Region: ATP-grasp_4; cl17255
697329004160	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
697329004161	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
697329004162	ATP-grasp domain; Region: ATP-grasp_4; cl17255
697329004163	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
697329004164	IMP binding site; other site
697329004165	dimer interface [polypeptide binding]; other site
697329004166	interdomain contacts; other site
697329004167	partial ornithine binding site; other site
697329004168	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329004169	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329004170	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329004171	DNA binding residues [nucleotide binding]
697329004172	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
697329004173	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
697329004174	Soluble P-type ATPase [General function prediction only]; Region: COG4087
697329004175	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
697329004176	metal-binding site [ion binding]
697329004177	Methyltransferase domain; Region: Methyltransf_31; pfam13847
697329004178	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329004179	S-adenosylmethionine binding site [chemical binding]; other site
697329004180	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
697329004181	dimerization interface [polypeptide binding]; other site
697329004182	putative DNA binding site [nucleotide binding]; other site
697329004183	putative Zn2+ binding site [ion binding]; other site
697329004184	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
697329004185	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
697329004186	substrate binding site [chemical binding]; other site
697329004187	ATP binding site [chemical binding]; other site
697329004188	FtsX-like permease family; Region: FtsX; pfam02687
697329004189	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329004190	FtsX-like permease family; Region: FtsX; pfam02687
697329004191	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329004192	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329004193	Walker A/P-loop; other site
697329004194	ATP binding site [chemical binding]; other site
697329004195	Q-loop/lid; other site
697329004196	ABC transporter signature motif; other site
697329004197	Walker B; other site
697329004198	D-loop; other site
697329004199	H-loop/switch region; other site
697329004200	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
697329004201	putative dimer interface [polypeptide binding]; other site
697329004202	catalytic triad [active]
697329004203	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
697329004204	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
697329004205	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
697329004206	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
697329004207	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
697329004208	intersubunit interface [polypeptide binding]; other site
697329004209	YodA lipocalin-like domain; Region: YodA; cl01365
697329004210	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
697329004211	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
697329004212	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
697329004213	Pectic acid lyase; Region: Pec_lyase; pfam09492
697329004214	putative pectinesterase; Region: PLN02432; cl01911
697329004215	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329004216	Interdomain contacts; other site
697329004217	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
697329004218	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
697329004219	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004220	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
697329004221	active site
697329004222	catalytic triad [active]
697329004223	oxyanion hole [active]
697329004224	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329004225	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329004226	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329004227	EF-hand domain pair; Region: EF_hand_5; pfam13499
697329004228	Dockerin type I repeat; Region: Dockerin_1; pfam00404
697329004229	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004230	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329004231	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
697329004232	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
697329004233	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
697329004234	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
697329004235	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
697329004236	dimer interface [polypeptide binding]; other site
697329004237	putative anticodon binding site; other site
697329004238	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
697329004239	motif 1; other site
697329004240	active site
697329004241	motif 2; other site
697329004242	motif 3; other site
697329004243	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_c; cd10311
697329004244	putative active site [active]
697329004245	catalytic site [active]
697329004246	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
697329004247	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329004248	ATP binding site [chemical binding]; other site
697329004249	putative Mg++ binding site [ion binding]; other site
697329004250	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329004251	nucleotide binding region [chemical binding]; other site
697329004252	ATP-binding site [chemical binding]; other site
697329004253	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
697329004254	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
697329004255	DNA methylase; Region: N6_N4_Mtase; pfam01555
697329004256	DNA methylase; Region: N6_N4_Mtase; pfam01555
697329004257	Restriction endonuclease [Defense mechanisms]; Region: COG3587
697329004258	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329004259	ATP binding site [chemical binding]; other site
697329004260	Predicted transcriptional regulator [Transcription]; Region: COG2378
697329004261	WYL domain; Region: WYL; pfam13280
697329004262	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
697329004263	Mg binding site [ion binding]; other site
697329004264	nucleotide binding site [chemical binding]; other site
697329004265	putative protofilament interface [polypeptide binding]; other site
697329004266	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
697329004267	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
697329004268	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329004269	AAA ATPase domain; Region: AAA_16; pfam13191
697329004270	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
697329004271	TPR motif; other site
697329004272	Tetratricopeptide repeat; Region: TPR_12; pfam13424
697329004273	binding surface
697329004274	Excisionase from transposon Tn916; Region: Tn916-Xis; pfam09035
697329004275	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
697329004276	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
697329004277	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329004278	Int/Topo IB signature motif; other site
697329004279	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
697329004280	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329004281	Int/Topo IB signature motif; other site
697329004282	Excisionase from transposon Tn916; Region: Tn916-Xis; pfam09035
697329004283	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329004284	WYL domain; Region: WYL; pfam13280
697329004285	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329004286	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329004287	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329004288	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329004289	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329004290	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329004291	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
697329004292	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
697329004293	Putative amidoligase enzyme; Region: Amidoligase_2; pfam12224
697329004294	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cd00352
697329004295	active site
697329004296	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
697329004297	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; cl01481
697329004298	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
697329004299	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
697329004300	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
697329004301	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
697329004302	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cl12040
697329004303	CRISPR/Cas system-associated protein Cas8c; Region: Cas8c_I-C; cl12004
697329004304	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cl01465
697329004305	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cd09637
697329004306	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-C; cd09721
697329004307	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
697329004308	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329004309	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329004310	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329004311	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329004312	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329004313	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329004314	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329004315	SUKH-3 immunity protein; Region: SUKH-3; pfam14433
697329004316	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329004317	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329004318	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329004319	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
697329004320	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
697329004321	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329004322	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
697329004323	putative sugar binding sites [chemical binding]; other site
697329004324	Q-X-W motif; other site
697329004325	Right handed beta helix region; Region: Beta_helix; pfam13229
697329004326	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
697329004327	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329004328	Walker A/P-loop; other site
697329004329	ATP binding site [chemical binding]; other site
697329004330	Q-loop/lid; other site
697329004331	ABC transporter signature motif; other site
697329004332	Walker B; other site
697329004333	D-loop; other site
697329004334	H-loop/switch region; other site
697329004335	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329004336	Interdomain contacts; other site
697329004337	Cytokine receptor motif; other site
697329004338	EF-hand domain pair; Region: EF_hand_5; pfam13499
697329004339	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329004340	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
697329004341	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
697329004342	putative acyl-acceptor binding pocket; other site
697329004343	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
697329004344	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329004345	acyl-activating enzyme (AAE) consensus motif; other site
697329004346	AMP binding site [chemical binding]; other site
697329004347	active site
697329004348	CoA binding site [chemical binding]; other site
697329004349	hopanoid C-3 methylase HpnR; Region: HpnR_B12_rSAM; TIGR04367
697329004350	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
697329004351	uracil transporter; Provisional; Region: PRK10720
697329004352	Sulfate transporter family; Region: Sulfate_transp; pfam00916
697329004353	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329004354	active site
697329004355	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329004356	active site
697329004357	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
697329004358	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329004359	active site
697329004360	Restriction endonuclease; Region: Mrr_cat; pfam04471
697329004361	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
697329004362	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
697329004363	prephenate dehydrogenase; Validated; Region: PRK08507
697329004364	Prephenate dehydrogenase; Region: PDH; pfam02153
697329004365	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
697329004366	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
697329004367	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
697329004368	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
697329004369	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329004370	FeS/SAM binding site; other site
697329004371	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
697329004372	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
697329004373	putative active site [active]
697329004374	putative metal binding site [ion binding]; other site
697329004375	putative alpha-glucosidase; Provisional; Region: PRK10658
697329004376	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
697329004377	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
697329004378	active site
697329004379	homotrimer interface [polypeptide binding]; other site
697329004380	catalytic site [active]
697329004381	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
697329004382	Conserved TM helix; Region: TM_helix; pfam05552
697329004383	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
697329004384	Mechanosensitive ion channel; Region: MS_channel; pfam00924
697329004385	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
697329004386	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329004387	S-adenosylmethionine binding site [chemical binding]; other site
697329004388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329004389	S-adenosylmethionine binding site [chemical binding]; other site
697329004390	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
697329004391	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329004392	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329004393	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
697329004394	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329004395	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329004396	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329004397	Repair protein; Region: Repair_PSII; pfam04536
697329004398	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
697329004399	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
697329004400	Catalytic domain of Protein Kinases; Region: PKc; cd00180
697329004401	Protein kinase domain; Region: Pkinase; pfam00069
697329004402	active site
697329004403	ATP binding site [chemical binding]; other site
697329004404	substrate binding site [chemical binding]; other site
697329004405	activation loop (A-loop); other site
697329004406	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329004407	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329004408	metal binding site [ion binding]; metal-binding site
697329004409	active site
697329004410	I-site; other site
697329004411	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
697329004412	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
697329004413	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
697329004414	ABC transporter; Region: ABC_tran_2; pfam12848
697329004415	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
697329004416	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
697329004417	Transposase domain (DUF772); Region: DUF772; pfam05598
697329004418	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
697329004419	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
697329004420	Predicted helicase [General function prediction only]; Region: COG4889
697329004421	N-terminal putative catalytic domain of uncharacterized HKD family nucleases fused to putative helicases from the Snf2-like family; Region: PLDc_N_Snf2_like; cd09178
697329004422	PLD-like domain; Region: PLDc_2; pfam13091
697329004423	putative homodimer interface [polypeptide binding]; other site
697329004424	putative active site [active]
697329004425	catalytic site [active]
697329004426	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
697329004427	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329004428	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
697329004429	nucleotide binding region [chemical binding]; other site
697329004430	ATP-binding site [chemical binding]; other site
697329004431	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
697329004432	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329004433	active site
697329004434	DNA binding site [nucleotide binding]
697329004435	Int/Topo IB signature motif; other site
697329004436	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
697329004437	generic binding surface II; other site
697329004438	generic binding surface I; other site
697329004439	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329004440	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
697329004441	CENP-A-nucleosome distal (CAD) centromere subunit; Region: CENP-Q; pfam13094
697329004442	CHAT domain; Region: CHAT; cl17868
697329004443	Transposon-encoded protein TnpW; Region: TnpW; pfam14202
697329004444	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329004445	Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a...; Region: SR_TndX_transposase; cd03770
697329004446	putative catalytic residues [active]
697329004447	catalytic nucleophile [active]
697329004448	Recombinase; Region: Recombinase; pfam07508
697329004449	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329004450	Domain of unknown function (DUF4368); Region: DUF4368; pfam14287
697329004451	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
697329004452	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
697329004453	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
697329004454	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329004455	catalytic residue [active]
697329004456	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
697329004457	putative acetyltransferase; Provisional; Region: PRK03624
697329004458	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329004459	Coenzyme A binding pocket [chemical binding]; other site
697329004460	spermidine synthase; Provisional; Region: PRK00811
697329004461	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329004462	S-adenosylmethionine binding site [chemical binding]; other site
697329004463	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
697329004464	agmatinase; Region: agmatinase; TIGR01230
697329004465	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
697329004466	putative active site [active]
697329004467	Mn binding site [ion binding]; other site
697329004468	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
697329004469	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
697329004470	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
697329004471	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
697329004472	minor groove reading motif; other site
697329004473	helix-hairpin-helix signature motif; other site
697329004474	substrate binding pocket [chemical binding]; other site
697329004475	active site
697329004476	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
697329004477	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329004478	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
697329004479	active site
697329004480	catalytic site [active]
697329004481	Domain of unknown function (DUF303); Region: DUF303; pfam03629
697329004482	UDP-glucose 4-epimerase; Region: PLN02240
697329004483	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
697329004484	NAD binding site [chemical binding]; other site
697329004485	homodimer interface [polypeptide binding]; other site
697329004486	active site
697329004487	substrate binding site [chemical binding]; other site
697329004488	Domain of unknown function (DUF4358); Region: DUF4358; pfam14270
697329004489	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
697329004490	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
697329004491	active site
697329004492	catalytic residues [active]
697329004493	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
697329004494	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
697329004495	catalytic residues [active]
697329004496	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
697329004497	Sporulation Regulator WhiA C terminal domain; Region: HTH_WhiA; pfam02650
697329004498	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
697329004499	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
697329004500	CoA binding domain; Region: CoA_binding; pfam02629
697329004501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
697329004502	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
697329004503	NlpC/P60 family; Region: NLPC_P60; pfam00877
697329004504	Stage II sporulation protein; Region: SpoIID; pfam08486
697329004505	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
697329004506	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
697329004507	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
697329004508	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
697329004509	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
697329004510	Cupin domain; Region: Cupin_2; cl17218
697329004511	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329004512	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329004513	CAAX protease self-immunity; Region: Abi; pfam02517
697329004514	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
697329004515	nucleoside/Zn binding site; other site
697329004516	dimer interface [polypeptide binding]; other site
697329004517	catalytic motif [active]
697329004518	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
697329004519	Rhamnogalacturonan lyase of the polysaccharide lyase family 11; Region: RGL11; cd10318
697329004520	metal binding site [ion binding]; metal-binding site
697329004521	active site
697329004522	recombination protein RecR; Reviewed; Region: recR; PRK00076
697329004523	RecR protein; Region: RecR; pfam02132
697329004524	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
697329004525	putative active site [active]
697329004526	putative metal-binding site [ion binding]; other site
697329004527	tetramer interface [polypeptide binding]; other site
697329004528	hypothetical protein; Validated; Region: PRK00153
697329004529	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
697329004530	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329004531	Walker A motif; other site
697329004532	ATP binding site [chemical binding]; other site
697329004533	Walker B motif; other site
697329004534	arginine finger; other site
697329004535	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
697329004536	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
697329004537	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
697329004538	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
697329004539	protein binding site [polypeptide binding]; other site
697329004540	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
697329004541	Spore germination protein; Region: Spore_permease; cl17796
697329004542	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
697329004543	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
697329004544	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
697329004545	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
697329004546	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
697329004547	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
697329004548	ligand binding site [chemical binding]; other site
697329004549	homodimer interface [polypeptide binding]; other site
697329004550	NAD(P) binding site [chemical binding]; other site
697329004551	trimer interface B [polypeptide binding]; other site
697329004552	trimer interface A [polypeptide binding]; other site
697329004553	Predicted periplasmic lipoprotein involved in iron transport [Inorganic ion transport and metabolism]; Region: COG2822
697329004554	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
697329004555	Putative small multi-drug export protein; Region: Sm_multidrug_ex; pfam06695
697329004556	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
697329004557	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
697329004558	Ligand Binding Site [chemical binding]; other site
697329004559	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
697329004560	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329004561	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329004562	motif II; other site
697329004563	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329004564	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
697329004565	acyl-activating enzyme (AAE) consensus motif; other site
697329004566	AMP binding site [chemical binding]; other site
697329004567	active site
697329004568	CoA binding site [chemical binding]; other site
697329004569	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
697329004570	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
697329004571	active site
697329004572	nucleophile elbow; other site
697329004573	phosphodiesterase YaeI; Provisional; Region: PRK11340
697329004574	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
697329004575	putative active site [active]
697329004576	putative metal binding site [ion binding]; other site
697329004577	dipeptidase PepV; Reviewed; Region: PRK07318
697329004578	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
697329004579	active site
697329004580	metal binding site [ion binding]; metal-binding site
697329004581	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329004582	dimerization interface [polypeptide binding]; other site
697329004583	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
697329004584	ligand binding site [chemical binding]; other site
697329004585	FIST N domain; Region: FIST; cl10701
697329004586	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329004587	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329004588	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329004589	ligand binding site [chemical binding]; other site
697329004590	dimerization interface [polypeptide binding]; other site
697329004591	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329004592	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
697329004593	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
697329004594	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
697329004595	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
697329004596	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
697329004597	active site
697329004598	catalytic tetrad [active]
697329004599	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
697329004600	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
697329004601	Terminase small subunit; Region: Terminase_2; cl01513
697329004602	Phage terminase large subunit; Region: Terminase_3; cl12054
697329004603	Terminase-like family; Region: Terminase_6; pfam03237
697329004604	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329004605	non-specific DNA binding site [nucleotide binding]; other site
697329004606	salt bridge; other site
697329004607	sequence-specific DNA binding site [nucleotide binding]; other site
697329004608	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
697329004609	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
697329004610	nucleotide binding site [chemical binding]; other site
697329004611	Type III pantothenate kinase; Region: Pan_kinase; cl17198
697329004612	Predicted membrane protein [Function unknown]; Region: COG4684
697329004613	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
697329004614	substrate binding site [chemical binding]; other site
697329004615	active site
697329004616	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
697329004617	metal binding site [ion binding]; metal-binding site
697329004618	ligand binding site [chemical binding]; other site
697329004619	CAAX protease self-immunity; Region: Abi; pfam02517
697329004620	Divergent PAP2 family; Region: DUF212; pfam02681
697329004621	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
697329004622	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
697329004623	active site
697329004624	metal binding site [ion binding]; metal-binding site
697329004625	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
697329004626	ZIP Zinc transporter; Region: Zip; pfam02535
697329004627	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
697329004628	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
697329004629	metal-binding site [ion binding]
697329004630	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
697329004631	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
697329004632	Protein of unknown function (DUF3793); Region: DUF3793; pfam12672
697329004633	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
697329004634	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
697329004635	FeoA domain; Region: FeoA; pfam04023
697329004636	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
697329004637	Ferrous iron transport protein B; Region: FeoB_N; pfam02421
697329004638	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
697329004639	G1 box; other site
697329004640	GTP/Mg2+ binding site [chemical binding]; other site
697329004641	Switch I region; other site
697329004642	G2 box; other site
697329004643	G3 box; other site
697329004644	Switch II region; other site
697329004645	G4 box; other site
697329004646	G5 box; other site
697329004647	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
697329004648	Nucleoside recognition; Region: Gate; pfam07670
697329004649	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
697329004650	Nucleoside recognition; Region: Gate; pfam07670
697329004651	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
697329004652	indolepyruvate ferredoxin oxidoreductase, alpha subunit; Region: IOR_alpha; TIGR03336
697329004653	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
697329004654	dimer interface [polypeptide binding]; other site
697329004655	PYR/PP interface [polypeptide binding]; other site
697329004656	TPP binding site [chemical binding]; other site
697329004657	substrate binding site [chemical binding]; other site
697329004658	Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008
697329004659	TPP-binding site; other site
697329004660	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
697329004661	indolepyruvate oxidoreductase subunit beta; Reviewed; Region: PRK06853
697329004662	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
697329004663	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
697329004664	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329004665	acyl-activating enzyme (AAE) consensus motif; other site
697329004666	AMP binding site [chemical binding]; other site
697329004667	active site
697329004668	CoA binding site [chemical binding]; other site
697329004669	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
697329004670	ACT domain-containing protein [General function prediction only]; Region: COG4747
697329004671	N-terminal ACT domain of a novel protein composed almost entirely of two tandem ACT domains; Region: ACT_Bt0572_1; cd04908
697329004672	C-terminal ACT domain of a novel protein composed of just two ACT domains; Region: ACT_Bt0572_2; cd04882
697329004673	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
697329004674	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
697329004675	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
697329004676	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
697329004677	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
697329004678	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
697329004679	elongation factor G; Reviewed; Region: PRK12740
697329004680	G1 box; other site
697329004681	putative GEF interaction site [polypeptide binding]; other site
697329004682	GTP/Mg2+ binding site [chemical binding]; other site
697329004683	Switch I region; other site
697329004684	G2 box; other site
697329004685	G3 box; other site
697329004686	Switch II region; other site
697329004687	G4 box; other site
697329004688	G5 box; other site
697329004689	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
697329004690	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
697329004691	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
697329004692	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
697329004693	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
697329004694	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
697329004695	active site
697329004696	metal-binding site
697329004697	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329004698	active site
697329004699	HIGH motif; other site
697329004700	nucleotide binding site [chemical binding]; other site
697329004701	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
697329004702	tetramer interface [polypeptide binding]; other site
697329004703	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
697329004704	active site
697329004705	Mg2+/Mn2+ binding site [ion binding]; other site
697329004706	phosphonopyruvate decarboxylase; Region: Ppyr-DeCO2ase; TIGR03297
697329004707	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
697329004708	PYR/PP interface [polypeptide binding]; other site
697329004709	dimer interface [polypeptide binding]; other site
697329004710	TPP binding site [chemical binding]; other site
697329004711	Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as...; Region: TPP_PpyrDC; cd03371
697329004712	TPP-binding site; other site
697329004713	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
697329004714	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
697329004715	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
697329004716	active site
697329004717	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329004718	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329004719	Walker A/P-loop; other site
697329004720	ATP binding site [chemical binding]; other site
697329004721	Q-loop/lid; other site
697329004722	ABC transporter signature motif; other site
697329004723	Walker B; other site
697329004724	D-loop; other site
697329004725	H-loop/switch region; other site
697329004726	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
697329004727	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
697329004728	hypothetical protein; Provisional; Region: PRK13663
697329004729	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329004730	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
697329004731	active site
697329004732	metal binding site [ion binding]; metal-binding site
697329004733	Transposase, Mutator family; Region: Transposase_mut; pfam00872
697329004734	MULE transposase domain; Region: MULE; pfam10551
697329004735	Transposase domain (DUF772); Region: DUF772; pfam05598
697329004736	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
697329004737	Fic/DOC family; Region: Fic; cl00960
697329004738	Predicted transcriptional regulators [Transcription]; Region: COG1725
697329004739	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329004740	DNA-binding site [nucleotide binding]; DNA binding site
697329004741	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329004742	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329004743	Walker A/P-loop; other site
697329004744	ATP binding site [chemical binding]; other site
697329004745	Q-loop/lid; other site
697329004746	ABC transporter signature motif; other site
697329004747	Walker B; other site
697329004748	D-loop; other site
697329004749	H-loop/switch region; other site
697329004750	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
697329004751	CAAX protease self-immunity; Region: Abi; pfam02517
697329004752	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329004753	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
697329004754	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329004755	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
697329004756	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329004757	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329004758	endoglucanase; Region: PLN02420
697329004759	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329004760	TraB family; Region: TraB; pfam01963
697329004761	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004762	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
697329004763	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
697329004764	Interdomain contacts; other site
697329004765	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
697329004766	active site residue [active]
697329004767	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436
697329004768	CPxP  motif; other site
697329004769	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
697329004770	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
697329004771	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
697329004772	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
697329004773	putative ATP binding site [chemical binding]; other site
697329004774	putative substrate interface [chemical binding]; other site
697329004775	Putative amidoligase enzyme; Region: Amidoligase_2; pfam12224
697329004776	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
697329004777	putative active site pocket [active]
697329004778	dimerization interface [polypeptide binding]; other site
697329004779	putative catalytic residue [active]
697329004780	Domain of unknown function (DUF4314); Region: DUF4314; pfam14192
697329004781	Domain of unknown function (DUF4313); Region: DUF4313; pfam14190
697329004782	HicB family; Region: HicB; pfam05534
697329004783	Domain of unknown function (DUF4314); Region: DUF4314; pfam14192
697329004784	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
697329004785	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
697329004786	cofactor binding site; other site
697329004787	DNA binding site [nucleotide binding]
697329004788	substrate interaction site [chemical binding]; other site
697329004789	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
697329004790	Prophage antirepressor [Transcription]; Region: COG3617
697329004791	BRO family, N-terminal domain; Region: Bro-N; smart01040
697329004792	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
697329004793	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
697329004794	YodL-like; Region: YodL; pfam14191
697329004795	Domain of unknown function (DUF3846); Region: DUF3846; pfam12957
697329004796	SpoVG; Region: SpoVG; cl00915
697329004797	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
697329004798	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
697329004799	domain interaction interfaces [polypeptide binding]; other site
697329004800	Cna protein B-type domain; Region: Cna_B; pfam05738
697329004801	Cna protein B-type domain; Region: Cna_B; pfam05738
697329004802	Cna protein B-type domain; Region: Cna_B; pfam05738
697329004803	Cna protein B-type domain; Region: Cna_B; pfam05738
697329004804	Cna protein B-type domain; Region: Cna_B; pfam05738
697329004805	Protein of unknown function (DUF3852); Region: DUF3852; pfam12963
697329004806	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
697329004807	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
697329004808	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
697329004809	active site
697329004810	metal binding site [ion binding]; metal-binding site
697329004811	interdomain interaction site; other site
697329004812	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
697329004813	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
697329004814	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329004815	DNA-binding site [nucleotide binding]; DNA binding site
697329004816	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
697329004817	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
697329004818	ABC exporter ATP-binding subunit, DevA family; Region: heterocyst_DevA; TIGR02982
697329004819	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329004820	Walker A/P-loop; other site
697329004821	ATP binding site [chemical binding]; other site
697329004822	Q-loop/lid; other site
697329004823	ABC transporter signature motif; other site
697329004824	Walker B; other site
697329004825	D-loop; other site
697329004826	H-loop/switch region; other site
697329004827	Bulb-type mannose-specific lectin. The domain contains a three-fold internal repeat (beta-prism architecture). The consensus sequence motif QXDXNXVXY is involved in alpha-D-mannose recognition. Lectins are carbohydrate-binding proteins which specifically...; Region: B_lectin; cd00028
697329004828	D-mannose binding lectin; Region: B_lectin; pfam01453
697329004829	mannose binding site [chemical binding]; other site
697329004830	dimerization interface [polypeptide binding]; other site
697329004831	Peptidase M15; Region: Peptidase_M15_3; pfam08291
697329004832	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329004833	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329004834	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329004835	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329004836	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329004837	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329004838	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329004839	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329004840	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329004841	Cellulose binding domain; Region: CBM_2; pfam00553
697329004842	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329004843	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329004844	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329004845	DNA binding residues [nucleotide binding]
697329004846	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329004847	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
697329004848	Walker A/P-loop; other site
697329004849	ATP binding site [chemical binding]; other site
697329004850	Q-loop/lid; other site
697329004851	ABC transporter signature motif; other site
697329004852	Walker B; other site
697329004853	D-loop; other site
697329004854	H-loop/switch region; other site
697329004855	Bulb-type mannose-specific lectin; Region: B_lectin; smart00108
697329004856	Bulb-type mannose-specific lectin. The domain contains a three-fold internal repeat (beta-prism architecture). The consensus sequence motif QXDXNXVXY is involved in alpha-D-mannose recognition. Lectins are carbohydrate-binding proteins which specifically...; Region: B_lectin; cd00028
697329004857	dimerization interface [polypeptide binding]; other site
697329004858	mannose binding site [chemical binding]; other site
697329004859	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
697329004860	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329004861	FtsX-like permease family; Region: FtsX; pfam02687
697329004862	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
697329004863	FtsX-like permease family; Region: FtsX; pfam02687
697329004864	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329004865	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329004866	Walker A/P-loop; other site
697329004867	ATP binding site [chemical binding]; other site
697329004868	Q-loop/lid; other site
697329004869	ABC transporter signature motif; other site
697329004870	Walker B; other site
697329004871	D-loop; other site
697329004872	H-loop/switch region; other site
697329004873	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329004874	Leucine rich repeat; Region: LRR_8; pfam13855
697329004875	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329004876	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329004877	Fibronectin type 3 domain; Region: FN3; smart00060
697329004878	Bacterial SH3 domain; Region: SH3_3; cl17532
697329004879	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329004880	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329004881	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329004882	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329004883	dimerization interface [polypeptide binding]; other site
697329004884	ligand binding site [chemical binding]; other site
697329004885	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329004886	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329004887	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329004888	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
697329004889	Ricin-type beta-trefoil; Region: RICIN; smart00458
697329004890	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329004891	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329004892	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
697329004893	putative active site [active]
697329004894	catalytic triad [active]
697329004895	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
697329004896	catalytic residues [active]
697329004897	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
697329004898	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
697329004899	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
697329004900	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
697329004901	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
697329004902	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
697329004903	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
697329004904	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
697329004905	active site residue [active]
697329004906	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
697329004907	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
697329004908	ligand binding site [chemical binding]; other site
697329004909	flexible hinge region; other site
697329004910	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
697329004911	putative switch regulator; other site
697329004912	non-specific DNA interactions [nucleotide binding]; other site
697329004913	DNA binding site [nucleotide binding]
697329004914	sequence specific DNA binding site [nucleotide binding]; other site
697329004915	putative cAMP binding site [chemical binding]; other site
697329004916	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004917	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
697329004918	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004919	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
697329004920	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329004921	dimerization interface [polypeptide binding]; other site
697329004922	ligand binding site [chemical binding]; other site
697329004923	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
697329004924	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
697329004925	RHS Repeat; Region: RHS_repeat; pfam05593
697329004926	RHS Repeat; Region: RHS_repeat; pfam05593
697329004927	RHS Repeat; Region: RHS_repeat; cl11982
697329004928	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
697329004929	RHS Repeat; Region: RHS_repeat; pfam05593
697329004930	RHS Repeat; Region: RHS_repeat; pfam05593
697329004931	RHS Repeat; Region: RHS_repeat; pfam05593
697329004932	RHS Repeat; Region: RHS_repeat; pfam05593
697329004933	RHS Repeat; Region: RHS_repeat; pfam05593
697329004934	RHS Repeat; Region: RHS_repeat; pfam05593
697329004935	RHS Repeat; Region: RHS_repeat; pfam05593
697329004936	RHS Repeat; Region: RHS_repeat; pfam05593
697329004937	RHS Repeat; Region: RHS_repeat; pfam05593
697329004938	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
697329004939	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
697329004940	protein-splicing catalytic site; other site
697329004941	thioester formation/cholesterol transfer; other site
697329004942	Pretoxin HINT domain; Region: PT-HINT; pfam07591
697329004943	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
697329004944	protein-splicing catalytic site; other site
697329004945	thioester formation/cholesterol transfer; other site
697329004946	Pretoxin HINT domain; Region: PT-HINT; pfam07591
697329004947	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cl17442
697329004948	protein-splicing catalytic site; other site
697329004949	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329004950	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329004951	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329004952	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329004953	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
697329004954	catalytic residues [active]
697329004955	catalytic nucleophile [active]
697329004956	Presynaptic Site I dimer interface [polypeptide binding]; other site
697329004957	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
697329004958	Synaptic Flat tetramer interface [polypeptide binding]; other site
697329004959	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329004960	Transposon-encoded protein TnpW; Region: TnpW; pfam14202
697329004961	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329004962	Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a...; Region: SR_TndX_transposase; cd03770
697329004963	putative catalytic residues [active]
697329004964	catalytic nucleophile [active]
697329004965	Recombinase; Region: Recombinase; pfam07508
697329004966	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329004967	Domain of unknown function (DUF4368); Region: DUF4368; pfam14287
697329004968	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329004969	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329004970	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329004971	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329004972	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329004973	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329004974	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
697329004975	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
697329004976	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
697329004977	active site
697329004978	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004979	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329004980	Putative esterase; Region: Esterase; pfam00756
697329004981	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
697329004982	CTP synthetase; Validated; Region: pyrG; PRK05380
697329004983	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
697329004984	Catalytic site [active]
697329004985	active site
697329004986	UTP binding site [chemical binding]; other site
697329004987	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
697329004988	active site
697329004989	putative oxyanion hole; other site
697329004990	catalytic triad [active]
697329004991	L,L-diaminopimelate aminotransferase; Validated; Region: PRK07590
697329004992	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
697329004993	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329004994	homodimer interface [polypeptide binding]; other site
697329004995	catalytic residue [active]
697329004996	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
697329004997	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
697329004998	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
697329004999	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
697329005000	Acyltransferase family; Region: Acyl_transf_3; pfam01757
697329005001	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
697329005002	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
697329005003	Interdomain contacts; other site
697329005004	Cytokine receptor motif; other site
697329005005	TIGR02452 family protein; Region: TIGR02452
697329005006	Uncharacterized protein conserved in bacteria (DUF2263); Region: DUF2263; pfam10021
697329005007	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
697329005008	Uncharacterized conserved protein [Function unknown]; Region: COG3287
697329005009	FIST N domain; Region: FIST; pfam08495
697329005010	FIST C domain; Region: FIST_C; pfam10442
697329005011	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329005012	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329005013	metal binding site [ion binding]; metal-binding site
697329005014	active site
697329005015	I-site; other site
697329005016	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
697329005017	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
697329005018	lichenase, member of glycosyl hydrolase family 16; Region: GH16_lichenase; cd02175
697329005019	Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]; Region: SKN1; COG2273
697329005020	active site
697329005021	active site
697329005022	catalytic residues [active]
697329005023	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329005024	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329005025	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329005026	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329005027	Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891
697329005028	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329005029	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329005030	active site
697329005031	phosphorylation site [posttranslational modification]
697329005032	intermolecular recognition site; other site
697329005033	dimerization interface [polypeptide binding]; other site
697329005034	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329005035	DNA binding site [nucleotide binding]
697329005036	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329005037	dimer interface [polypeptide binding]; other site
697329005038	phosphorylation site [posttranslational modification]
697329005039	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329005040	ATP binding site [chemical binding]; other site
697329005041	Mg2+ binding site [ion binding]; other site
697329005042	G-X-G motif; other site
697329005043	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
697329005044	putative metal binding residues [ion binding]; other site
697329005045	signature motif; other site
697329005046	dimer interface [polypeptide binding]; other site
697329005047	active site
697329005048	polyP binding site; other site
697329005049	substrate binding site [chemical binding]; other site
697329005050	acceptor-phosphate pocket; other site
697329005051	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
697329005052	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
697329005053	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329005054	Zn2+ binding site [ion binding]; other site
697329005055	Mg2+ binding site [ion binding]; other site
697329005056	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
697329005057	Uncharacterized conserved protein [Function unknown]; Region: COG1739
697329005058	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
697329005059	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
697329005060	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
697329005061	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329005062	Zn2+ binding site [ion binding]; other site
697329005063	Mg2+ binding site [ion binding]; other site
697329005064	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
697329005065	DNA primase; Validated; Region: dnaG; PRK05667
697329005066	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329005067	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
697329005068	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
697329005069	active site
697329005070	metal binding site [ion binding]; metal-binding site
697329005071	interdomain interaction site; other site
697329005072	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
697329005073	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
697329005074	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
697329005075	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
697329005076	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329005077	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
697329005078	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329005079	DNA binding residues [nucleotide binding]
697329005080	Predicted transcriptional regulator [Transcription]; Region: COG1959
697329005081	Transcriptional regulator; Region: Rrf2; pfam02082
697329005082	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
697329005083	active site
697329005084	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
697329005085	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329005086	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329005087	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329005088	phosphonate metabolim protein, transferase hexapeptide repeat family; Region: phn_thr-fam; TIGR03308
697329005089	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
697329005090	trimer interface [polypeptide binding]; other site
697329005091	active site
697329005092	substrate binding site [chemical binding]; other site
697329005093	CoA binding site [chemical binding]; other site
697329005094	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329005095	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
697329005096	active site
697329005097	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
697329005098	Ligand Binding Site [chemical binding]; other site
697329005099	Molecular Tunnel; other site
697329005100	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
697329005101	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
697329005102	MoxR-like ATPases [General function prediction only]; Region: COG0714
697329005103	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
697329005104	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
697329005105	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
697329005106	metal ion-dependent adhesion site (MIDAS); other site
697329005107	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
697329005108	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
697329005109	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
697329005110	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329005111	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329005112	Walker A/P-loop; other site
697329005113	ATP binding site [chemical binding]; other site
697329005114	Q-loop/lid; other site
697329005115	ABC transporter signature motif; other site
697329005116	Walker B; other site
697329005117	D-loop; other site
697329005118	H-loop/switch region; other site
697329005119	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
697329005120	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329005121	FtsX-like permease family; Region: FtsX; pfam02687
697329005122	Accessory gene regulator B; Region: AgrB; pfam04647
697329005123	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329005124	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329005125	ATP binding site [chemical binding]; other site
697329005126	Mg2+ binding site [ion binding]; other site
697329005127	G-X-G motif; other site
697329005128	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
697329005129	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329005130	active site
697329005131	phosphorylation site [posttranslational modification]
697329005132	intermolecular recognition site; other site
697329005133	dimerization interface [polypeptide binding]; other site
697329005134	LytTr DNA-binding domain; Region: LytTR; pfam04397
697329005135	Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain [Cell division and chromosome partitioning]; Region: CYK3; COG5279
697329005136	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
697329005137	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329005138	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
697329005139	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329005140	motif II; other site
697329005141	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
697329005142	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329005143	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329005144	active site
697329005145	phosphorylation site [posttranslational modification]
697329005146	intermolecular recognition site; other site
697329005147	dimerization interface [polypeptide binding]; other site
697329005148	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329005149	DNA binding site [nucleotide binding]
697329005150	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329005151	HAMP domain; Region: HAMP; pfam00672
697329005152	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329005153	dimer interface [polypeptide binding]; other site
697329005154	phosphorylation site [posttranslational modification]
697329005155	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329005156	ATP binding site [chemical binding]; other site
697329005157	Mg2+ binding site [ion binding]; other site
697329005158	G-X-G motif; other site
697329005159	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
697329005160	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
697329005161	active site
697329005162	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329005163	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329005164	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329005165	DNA binding residues [nucleotide binding]
697329005166	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329005167	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329005168	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329005169	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329005170	DNA binding residues [nucleotide binding]
697329005171	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
697329005172	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
697329005173	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
697329005174	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329005175	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
697329005176	Predicted transcriptional regulators [Transcription]; Region: COG1725
697329005177	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329005178	DNA-binding site [nucleotide binding]; DNA binding site
697329005179	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329005180	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329005181	Walker A/P-loop; other site
697329005182	ATP binding site [chemical binding]; other site
697329005183	Q-loop/lid; other site
697329005184	ABC transporter signature motif; other site
697329005185	Walker B; other site
697329005186	D-loop; other site
697329005187	H-loop/switch region; other site
697329005188	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
697329005189	dimer interface [polypeptide binding]; other site
697329005190	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
697329005191	dimer interface [polypeptide binding]; other site
697329005192	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
697329005193	dimer interface [polypeptide binding]; other site
697329005194	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
697329005195	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
697329005196	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
697329005197	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
697329005198	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
697329005199	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329005200	motif II; other site
697329005201	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
697329005202	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329005203	non-specific DNA binding site [nucleotide binding]; other site
697329005204	salt bridge; other site
697329005205	sequence-specific DNA binding site [nucleotide binding]; other site
697329005206	Protein of unknown function (DUF3737); Region: DUF3737; pfam12541
697329005207	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
697329005208	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329005209	DNA binding residues [nucleotide binding]
697329005210	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cl00252
697329005211	alpha-galactosidase; Region: PLN02808; cl17638
697329005212	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
697329005213	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329005214	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329005215	endoglucanase; Region: PLN02308
697329005216	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329005217	The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains.   LytC is composed of a...; Region: GH25_LytC-like; cd06414
697329005218	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
697329005219	active site
697329005220	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
697329005221	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
697329005222	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
697329005223	active site
697329005224	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329005225	Protein of unknown function DUF99; Region: DUF99; cl00704
697329005226	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
697329005227	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
697329005228	active site
697329005229	catalytic tetrad [active]
697329005230	Glycine rich protein; Region: Gly_rich; pfam12810
697329005231	Cna protein B-type domain; Region: Cna_B; pfam05738
697329005232	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
697329005233	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
697329005234	active site
697329005235	catalytic site [active]
697329005236	Uncharacterized conserved protein [Function unknown]; Region: COG4925
697329005237	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
697329005238	active site
697329005239	substrate binding site [chemical binding]; other site
697329005240	trimer interface [polypeptide binding]; other site
697329005241	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
697329005242	CoA binding site [chemical binding]; other site
697329005243	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
697329005244	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
697329005245	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329005246	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329005247	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
697329005248	dimerization interface [polypeptide binding]; other site
697329005249	Domain of unknown function (DUF4317); Region: DUF4317; pfam14199
697329005250	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
697329005251	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329005252	RNA binding surface [nucleotide binding]; other site
697329005253	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
697329005254	IHF - DNA interface [nucleotide binding]; other site
697329005255	IHF dimer interface [polypeptide binding]; other site
697329005256	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
697329005257	homodimer interface [polypeptide binding]; other site
697329005258	metal binding site [ion binding]; metal-binding site
697329005259	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
697329005260	homodimer interface [polypeptide binding]; other site
697329005261	active site
697329005262	putative chemical substrate binding site [chemical binding]; other site
697329005263	metal binding site [ion binding]; metal-binding site
697329005264	stage V sporulation protein B; Region: spore_V_B; TIGR02900
697329005265	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
697329005266	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
697329005267	active site
697329005268	NTP binding site [chemical binding]; other site
697329005269	metal binding triad [ion binding]; metal-binding site
697329005270	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
697329005271	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
697329005272	S-ribosylhomocysteinase; Provisional; Region: PRK02260
697329005273	Uncharacterized conserved protein [Function unknown]; Region: COG0398
697329005274	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
697329005275	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
697329005276	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
697329005277	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
697329005278	FOG: CBS domain [General function prediction only]; Region: COG0517
697329005279	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329005280	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329005281	metal binding site [ion binding]; metal-binding site
697329005282	active site
697329005283	I-site; other site
697329005284	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
697329005285	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
697329005286	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
697329005287	active site
697329005288	intersubunit interactions; other site
697329005289	catalytic residue [active]
697329005290	Domain of unknown function (DUF4173); Region: DUF4173; pfam13777
697329005291	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329005292	salt bridge; other site
697329005293	non-specific DNA binding site [nucleotide binding]; other site
697329005294	sequence-specific DNA binding site [nucleotide binding]; other site
697329005295	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
697329005296	RNA 2'-phosphotransferase, Tpt1 / KptA family; Region: PTS_2-RNA; pfam01885
697329005297	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329005298	S-adenosylmethionine binding site [chemical binding]; other site
697329005299	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
697329005300	galactokinase; Provisional; Region: PRK03817
697329005301	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
697329005302	GMP synthase; Reviewed; Region: guaA; PRK00074
697329005303	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
697329005304	AMP/PPi binding site [chemical binding]; other site
697329005305	candidate oxyanion hole; other site
697329005306	catalytic triad [active]
697329005307	potential glutamine specificity residues [chemical binding]; other site
697329005308	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
697329005309	ATP Binding subdomain [chemical binding]; other site
697329005310	Ligand Binding sites [chemical binding]; other site
697329005311	Dimerization subdomain; other site
697329005312	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329005313	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329005314	active site
697329005315	phosphorylation site [posttranslational modification]
697329005316	intermolecular recognition site; other site
697329005317	dimerization interface [polypeptide binding]; other site
697329005318	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329005319	DNA binding site [nucleotide binding]
697329005320	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329005321	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329005322	dimer interface [polypeptide binding]; other site
697329005323	phosphorylation site [posttranslational modification]
697329005324	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329005325	ATP binding site [chemical binding]; other site
697329005326	Mg2+ binding site [ion binding]; other site
697329005327	G-X-G motif; other site
697329005328	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
697329005329	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
697329005330	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
697329005331	dimer interface [polypeptide binding]; other site
697329005332	active site
697329005333	metal binding site [ion binding]; metal-binding site
697329005334	classical (c) SDRs; Region: SDR_c; cd05233
697329005335	NAD(P) binding site [chemical binding]; other site
697329005336	active site
697329005337	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
697329005338	atypical (a) SDRs, subgroup 1; Region: SDR_a1; cd05265
697329005339	putative NAD(P) binding site [chemical binding]; other site
697329005340	active site
697329005341	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
697329005342	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
697329005343	catalytic motif [active]
697329005344	Zn binding site [ion binding]; other site
697329005345	RibD C-terminal domain; Region: RibD_C; cl17279
697329005346	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
697329005347	Lumazine binding domain; Region: Lum_binding; pfam00677
697329005348	Lumazine binding domain; Region: Lum_binding; pfam00677
697329005349	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
697329005350	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
697329005351	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
697329005352	dimerization interface [polypeptide binding]; other site
697329005353	active site
697329005354	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
697329005355	homopentamer interface [polypeptide binding]; other site
697329005356	active site
697329005357	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329005358	active site
697329005359	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
697329005360	stage II sporulation protein P; Region: spore_II_P; TIGR02867
697329005361	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329005362	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329005363	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329005364	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329005365	metal binding site [ion binding]; metal-binding site
697329005366	active site
697329005367	I-site; other site
697329005368	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
697329005369	dockerin binding interface; other site
697329005370	Cadherin-like beta sandwich domain; Region: Cadherin-like; pfam12733
697329005371	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
697329005372	putative active site [active]
697329005373	putative metal binding site [ion binding]; other site
697329005374	HAMP domain; Region: HAMP; pfam00672
697329005375	dimerization interface [polypeptide binding]; other site
697329005376	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
697329005377	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
697329005378	dimer interface [polypeptide binding]; other site
697329005379	putative CheW interface [polypeptide binding]; other site
697329005380	6-phosphofructokinase; Provisional; Region: PRK03202
697329005381	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
697329005382	active site
697329005383	ADP/pyrophosphate binding site [chemical binding]; other site
697329005384	dimerization interface [polypeptide binding]; other site
697329005385	allosteric effector site; other site
697329005386	fructose-1,6-bisphosphate binding site; other site
697329005387	peptidase T; Region: peptidase-T; TIGR01882
697329005388	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
697329005389	metal binding site [ion binding]; metal-binding site
697329005390	dimer interface [polypeptide binding]; other site
697329005391	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
697329005392	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
697329005393	Ligand Binding Site [chemical binding]; other site
697329005394	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
697329005395	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
697329005396	nudix motif; other site
697329005397	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
697329005398	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
697329005399	Right handed beta helix region; Region: Beta_helix; pfam13229
697329005400	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
697329005401	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329005402	putative active site [active]
697329005403	putative metal binding site [ion binding]; other site
697329005404	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
697329005405	Part of AAA domain; Region: AAA_19; pfam13245
697329005406	Family description; Region: UvrD_C_2; pfam13538
697329005407	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
697329005408	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
697329005409	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
697329005410	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
697329005411	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
697329005412	DHH family; Region: DHH; pfam01368
697329005413	DHHA1 domain; Region: DHHA1; pfam02272
697329005414	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
697329005415	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
697329005416	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
697329005417	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
697329005418	replicative DNA helicase; Region: DnaB; TIGR00665
697329005419	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
697329005420	Walker A motif; other site
697329005421	ATP binding site [chemical binding]; other site
697329005422	Walker B motif; other site
697329005423	DNA binding loops [nucleotide binding]
697329005424	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
697329005425	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
697329005426	TilS substrate C-terminal domain; Region: TilS_C; smart00977
697329005427	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
697329005428	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329005429	Walker B motif; other site
697329005430	arginine finger; other site
697329005431	Peptidase family M41; Region: Peptidase_M41; pfam01434
697329005432	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
697329005433	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329005434	putative active site [active]
697329005435	metal binding site [ion binding]; metal-binding site
697329005436	homodimer binding site [polypeptide binding]; other site
697329005437	Stage V sporulation protein S (SpoVS); Region: SpoVS; cl01005
697329005438	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
697329005439	propionate/acetate kinase; Provisional; Region: PRK12379
697329005440	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
697329005441	Predicted nucleotidyltransferase [General function prediction only]; Region: COG1323
697329005442	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
697329005443	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
697329005444	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
697329005445	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
697329005446	DNA interaction; other site
697329005447	Metal-binding active site; metal-binding site
697329005448	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
697329005449	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
697329005450	active site
697329005451	sporulation sigma factor SigG; Reviewed; Region: PRK08215
697329005452	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329005453	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
697329005454	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329005455	DNA binding residues [nucleotide binding]
697329005456	Protein implicated in RNA metabolism, contains PRC-barrel domain [General    function prediction only]; Region: COG1873; cl17889
697329005457	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
697329005458	rRNA interaction site [nucleotide binding]; other site
697329005459	S8 interaction site; other site
697329005460	putative laminin-1 binding site; other site
697329005461	elongation factor Ts; Provisional; Region: tsf; PRK09377
697329005462	UBA/TS-N domain; Region: UBA; pfam00627
697329005463	Elongation factor TS; Region: EF_TS; pfam00889
697329005464	Elongation factor TS; Region: EF_TS; pfam00889
697329005465	DNA protecting protein DprA; Region: dprA; TIGR00732
697329005466	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
697329005467	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
697329005468	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
697329005469	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
697329005470	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
697329005471	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
697329005472	hypothetical protein; Provisional; Region: PRK06851
697329005473	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
697329005474	DHH family; Region: DHH; pfam01368
697329005475	DHHA1 domain; Region: DHHA1; pfam02272
697329005476	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
697329005477	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329005478	Zn2+ binding site [ion binding]; other site
697329005479	Mg2+ binding site [ion binding]; other site
697329005480	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
697329005481	synthetase active site [active]
697329005482	NTP binding site [chemical binding]; other site
697329005483	metal binding site [ion binding]; metal-binding site
697329005484	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
697329005485	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
697329005486	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
697329005487	coproporphyrinogen dehydrogenase HemZ; Region: rSAM_HemZ; TIGR03994
697329005488	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329005489	FeS/SAM binding site; other site
697329005490	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
697329005491	TRAM domain; Region: TRAM; cl01282
697329005492	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329005493	S-adenosylmethionine binding site [chemical binding]; other site
697329005494	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
697329005495	Phosphotransferase enzyme family; Region: APH; pfam01636
697329005496	active site
697329005497	ATP binding site [chemical binding]; other site
697329005498	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
697329005499	substrate binding site [chemical binding]; other site
697329005500	TM1410 hypothetical-related protein; Region: DUF297; pfam03537
697329005501	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
697329005502	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329005503	active site
697329005504	metal binding site [ion binding]; metal-binding site
697329005505	homotetramer interface [polypeptide binding]; other site
697329005506	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329005507	dimerization interface [polypeptide binding]; other site
697329005508	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329005509	ligand binding site [chemical binding]; other site
697329005510	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329005511	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329005512	metal binding site [ion binding]; metal-binding site
697329005513	active site
697329005514	I-site; other site
697329005515	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
697329005516	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
697329005517	inhibitor-cofactor binding pocket; inhibition site
697329005518	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329005519	catalytic residue [active]
697329005520	AAA domain; Region: AAA_26; pfam13500
697329005521	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
697329005522	biotin synthase; Region: bioB; TIGR00433
697329005523	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329005524	FeS/SAM binding site; other site
697329005525	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
697329005526	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
697329005527	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
697329005528	ligand binding site [chemical binding]; other site
697329005529	active site
697329005530	UGI interface [polypeptide binding]; other site
697329005531	catalytic site [active]
697329005532	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329005533	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
697329005534	Protein of unknown function (DUF2933); Region: DUF2933; pfam11666
697329005535	Protein of unknown function DUF58; Region: DUF58; pfam01882
697329005536	MoxR-like ATPases [General function prediction only]; Region: COG0714
697329005537	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329005538	Walker A motif; other site
697329005539	ATP binding site [chemical binding]; other site
697329005540	Walker B motif; other site
697329005541	arginine finger; other site
697329005542	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
697329005543	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
697329005544	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
697329005545	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
697329005546	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
697329005547	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
697329005548	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
697329005549	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
697329005550	FMN binding site [chemical binding]; other site
697329005551	dimer interface [polypeptide binding]; other site
697329005552	glucan-binding repeat; Region: glucan_65_rpt; TIGR04035
697329005553	glucan-binding repeat; Region: glucan_65_rpt; TIGR04035
697329005554	glucan-binding repeat; Region: glucan_65_rpt; TIGR04035
697329005555	glucan-binding repeat; Region: glucan_65_rpt; TIGR04035
697329005556	glucan-binding repeat; Region: glucan_65_rpt; TIGR04035
697329005557	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
697329005558	MarR family; Region: MarR; pfam01047
697329005559	von Willebrand factor; Region: vWF_A; pfam12450
697329005560	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
697329005561	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
697329005562	metal ion-dependent adhesion site (MIDAS); other site
697329005563	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
697329005564	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
697329005565	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329005566	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329005567	DNA binding residues [nucleotide binding]
697329005568	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
697329005569	RNA/DNA hybrid binding site [nucleotide binding]; other site
697329005570	active site
697329005571	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
697329005572	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
697329005573	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329005574	catalytic residue [active]
697329005575	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
697329005576	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
697329005577	Ligand Binding Site [chemical binding]; other site
697329005578	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
697329005579	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
697329005580	substrate binding site [chemical binding]; other site
697329005581	active site
697329005582	catalytic residues [active]
697329005583	heterodimer interface [polypeptide binding]; other site
697329005584	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
697329005585	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
697329005586	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329005587	catalytic residue [active]
697329005588	Chorismate mutase type II; Region: CM_2; smart00830
697329005589	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
697329005590	active site
697329005591	ribulose/triose binding site [chemical binding]; other site
697329005592	phosphate binding site [ion binding]; other site
697329005593	substrate (anthranilate) binding pocket [chemical binding]; other site
697329005594	product (indole) binding pocket [chemical binding]; other site
697329005595	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK14607
697329005596	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
697329005597	glutamine binding [chemical binding]; other site
697329005598	catalytic triad [active]
697329005599	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
697329005600	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
697329005601	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
697329005602	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
697329005603	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
697329005604	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
697329005605	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
697329005606	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
697329005607	putative FMN binding site [chemical binding]; other site
697329005608	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cd06462
697329005609	Catalytic site [active]
697329005610	SynChlorMet cassette protein ScmC; Region: SCM_chp_ScmC; TIGR04249
697329005611	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
697329005612	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
697329005613	Domain of unknown function DUF20; Region: UPF0118; pfam01594
697329005614	stage III sporulation protein AA; Region: spore_III_AA; TIGR02858
697329005615	NTPase; Region: NTPase_1; cl17478
697329005616	Stage III sporulation protein AB (spore_III_AB); Region: Spore_III_AB; cl08022
697329005617	stage III sporulation protein AC; Region: spore_III_AC; TIGR02848
697329005618	Stage III sporulation protein AC/AD protein family; Region: SpoIIIAC; cl05961
697329005619	Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; cl09771
697329005620	stage III sporulation protein AG; Region: spore_III_AG; TIGR02830
697329005621	SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685
697329005622	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
697329005623	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
697329005624	nucleotide binding pocket [chemical binding]; other site
697329005625	K-X-D-G motif; other site
697329005626	catalytic site [active]
697329005627	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
697329005628	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
697329005629	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
697329005630	Dimer interface [polypeptide binding]; other site
697329005631	BRCT sequence motif; other site
697329005632	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329005633	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
697329005634	Walker A motif; other site
697329005635	ATP binding site [chemical binding]; other site
697329005636	Walker B motif; other site
697329005637	arginine finger; other site
697329005638	DNA ligase, ATP-dependent, PP_1105 family; Region: DNA_lig_bact; TIGR04120
697329005639	Domain of unknown function (DUF4262); Region: DUF4262; pfam14081
697329005640	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
697329005641	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
697329005642	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
697329005643	dimerization interface [polypeptide binding]; other site
697329005644	ATP binding site [chemical binding]; other site
697329005645	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
697329005646	dimerization interface [polypeptide binding]; other site
697329005647	ATP binding site [chemical binding]; other site
697329005648	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
697329005649	putative active site [active]
697329005650	catalytic triad [active]
697329005651	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
697329005652	putative dimer interface [polypeptide binding]; other site
697329005653	catalytic triad [active]
697329005654	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
697329005655	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
697329005656	AsnC family; Region: AsnC_trans_reg; pfam01037
697329005657	hypothetical protein; Validated; Region: PRK07682
697329005658	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
697329005659	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329005660	homodimer interface [polypeptide binding]; other site
697329005661	catalytic residue [active]
697329005662	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
697329005663	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
697329005664	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
697329005665	Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993
697329005666	Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins [General function prediction only]; Region: PflX; COG1313
697329005667	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
697329005668	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
697329005669	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329005670	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329005671	Uncharacterized conserved protein [Function unknown]; Region: COG1434
697329005672	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
697329005673	putative active site [active]
697329005674	PTS HPr component phosphorylation site; Region: PTS-HPr; pfam00381
697329005675	regulatory phosphorylation site [posttranslational modification]; other site
697329005676	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
697329005677	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
697329005678	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329005679	FeS/SAM binding site; other site
697329005680	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329005681	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
697329005682	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
697329005683	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329005684	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
697329005685	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329005686	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329005687	Coenzyme A binding pocket [chemical binding]; other site
697329005688	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329005689	Radical SAM superfamily; Region: Radical_SAM; pfam04055
697329005690	FeS/SAM binding site; other site
697329005691	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900
697329005692	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
697329005693	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
697329005694	active site
697329005695	HIGH motif; other site
697329005696	dimer interface [polypeptide binding]; other site
697329005697	KMSKS motif; other site
697329005698	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329005699	RNA binding surface [nucleotide binding]; other site
697329005700	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
697329005701	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329005702	S-adenosylmethionine binding site [chemical binding]; other site
697329005703	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
697329005704	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
697329005705	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
697329005706	GDP-binding site [chemical binding]; other site
697329005707	ACT binding site; other site
697329005708	IMP binding site; other site
697329005709	Bacitracin resistance protein BacA; Region: BacA; pfam02673
697329005710	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
697329005711	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
697329005712	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
697329005713	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
697329005714	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
697329005715	Protein of unknown function (DUF3006); Region: DUF3006; pfam11213
697329005716	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
697329005717	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
697329005718	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
697329005719	putative active site [active]
697329005720	flavoprotein, HI0933 family; Region: TIGR00275
697329005721	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
697329005722	cytidylate kinase; Provisional; Region: cmk; PRK00023
697329005723	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
697329005724	CMP-binding site; other site
697329005725	The sites determining sugar specificity; other site
697329005726	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
697329005727	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
697329005728	putative acyl-acceptor binding pocket; other site
697329005729	4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; Reviewed; Region: PRK00087
697329005730	LytB protein; Region: LYTB; cl00507
697329005731	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
697329005732	RNA binding site [nucleotide binding]; other site
697329005733	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
697329005734	RNA binding site [nucleotide binding]; other site
697329005735	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
697329005736	RNA binding site [nucleotide binding]; other site
697329005737	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
697329005738	RNA binding site [nucleotide binding]; other site
697329005739	domain interface; other site
697329005740	Transglycosylase; Region: Transgly; pfam00912
697329005741	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
697329005742	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
697329005743	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
697329005744	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
697329005745	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
697329005746	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
697329005747	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329005748	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329005749	motif II; other site
697329005750	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
697329005751	Transposase IS200 like; Region: Y1_Tnp; pfam01797
697329005752	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
697329005753	substrate binding site; other site
697329005754	dimer interface; other site
697329005755	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
697329005756	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
697329005757	phosphoribosylpyrophosphate synthetase; Provisional; Region: PRK06827
697329005758	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
697329005759	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329005760	active site
697329005761	phosphoserine phosphatase; Provisional; Region: thrH; PRK13582
697329005762	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
697329005763	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
697329005764	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
697329005765	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
697329005766	NAD(P) binding site [chemical binding]; other site
697329005767	homodimer interface [polypeptide binding]; other site
697329005768	substrate binding site [chemical binding]; other site
697329005769	active site
697329005770	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
697329005771	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
697329005772	ArsC family; Region: ArsC; pfam03960
697329005773	putative ArsC-like catalytic residues; other site
697329005774	putative TRX-like catalytic residues [active]
697329005775	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
697329005776	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
697329005777	active site
697329005778	substrate-binding site [chemical binding]; other site
697329005779	metal-binding site [ion binding]
697329005780	ATP binding site [chemical binding]; other site
697329005781	Immunity protein Imm6; Region: Imm6; pfam14434
697329005782	ribonuclease Z; Region: RNase_Z; TIGR02651
697329005783	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329005784	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
697329005785	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
697329005786	recombination factor protein RarA; Reviewed; Region: PRK13342
697329005787	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329005788	Walker A motif; other site
697329005789	ATP binding site [chemical binding]; other site
697329005790	Walker B motif; other site
697329005791	arginine finger; other site
697329005792	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
697329005793	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cd05709
697329005794	active site
697329005795	putative substrate binding region [chemical binding]; other site
697329005796	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
697329005797	RNA binding site [nucleotide binding]; other site
697329005798	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
697329005799	RNA binding site [nucleotide binding]; other site
697329005800	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329005801	Interdomain contacts; other site
697329005802	Cytokine receptor motif; other site
697329005803	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
697329005804	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
697329005805	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
697329005806	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
697329005807	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
697329005808	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
697329005809	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
697329005810	Predicted HD-superfamily hydrolase [General function prediction only]; Region: COG3481
697329005811	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
697329005812	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329005813	motif II; other site
697329005814	hypothetical protein; Provisional; Region: PRK11820
697329005815	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
697329005816	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
697329005817	hypothetical protein; Provisional; Region: PRK04323
697329005818	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
697329005819	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
697329005820	catalytic site [active]
697329005821	G-X2-G-X-G-K; other site
697329005822	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
697329005823	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329005824	primosomal protein N' Region: priA; TIGR00595
697329005825	ATP binding site [chemical binding]; other site
697329005826	putative Mg++ binding site [ion binding]; other site
697329005827	helicase superfamily c-terminal domain; Region: HELICc; smart00490
697329005828	ATP-binding site [chemical binding]; other site
697329005829	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
697329005830	active site
697329005831	catalytic residues [active]
697329005832	metal binding site [ion binding]; metal-binding site
697329005833	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
697329005834	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
697329005835	putative active site [active]
697329005836	substrate binding site [chemical binding]; other site
697329005837	putative cosubstrate binding site; other site
697329005838	catalytic site [active]
697329005839	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
697329005840	substrate binding site [chemical binding]; other site
697329005841	16S rRNA methyltransferase B; Provisional; Region: PRK14902
697329005842	NusB family; Region: NusB; pfam01029
697329005843	putative RNA binding site [nucleotide binding]; other site
697329005844	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
697329005845	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14454
697329005846	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329005847	FeS/SAM binding site; other site
697329005848	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
697329005849	active site
697329005850	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
697329005851	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
697329005852	active site
697329005853	ATP binding site [chemical binding]; other site
697329005854	substrate binding site [chemical binding]; other site
697329005855	activation loop (A-loop); other site
697329005856	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329005857	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329005858	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329005859	GTPase RsgA; Reviewed; Region: PRK00098
697329005860	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
697329005861	RNA binding site [nucleotide binding]; other site
697329005862	homodimer interface [polypeptide binding]; other site
697329005863	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
697329005864	GTPase/Zn-binding domain interface [polypeptide binding]; other site
697329005865	GTP/Mg2+ binding site [chemical binding]; other site
697329005866	G4 box; other site
697329005867	G5 box; other site
697329005868	G1 box; other site
697329005869	Switch I region; other site
697329005870	G2 box; other site
697329005871	G3 box; other site
697329005872	Switch II region; other site
697329005873	Thiamine pyrophosphokinase; Region: TPK; cd07995
697329005874	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
697329005875	active site
697329005876	dimerization interface [polypeptide binding]; other site
697329005877	thiamine binding site [chemical binding]; other site
697329005878	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
697329005879	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329005880	dimer interface [polypeptide binding]; other site
697329005881	conserved gate region; other site
697329005882	putative PBP binding loops; other site
697329005883	ABC-ATPase subunit interface; other site
697329005884	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329005885	dimer interface [polypeptide binding]; other site
697329005886	conserved gate region; other site
697329005887	putative PBP binding loops; other site
697329005888	ABC-ATPase subunit interface; other site
697329005889	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329005890	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
697329005891	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; cl00674
697329005892	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
697329005893	Cation efflux family; Region: Cation_efflux; pfam01545
697329005894	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
697329005895	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
697329005896	DNA replication protein DnaC; Validated; Region: PRK06835
697329005897	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329005898	Walker A motif; other site
697329005899	ATP binding site [chemical binding]; other site
697329005900	Walker B motif; other site
697329005901	Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075
697329005902	Lipase (class 2); Region: Lipase_2; pfam01674
697329005903	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
697329005904	MutS domain III; Region: MutS_III; pfam05192
697329005905	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329005906	Walker A/P-loop; other site
697329005907	ATP binding site [chemical binding]; other site
697329005908	Q-loop/lid; other site
697329005909	ABC transporter signature motif; other site
697329005910	Walker B; other site
697329005911	D-loop; other site
697329005912	H-loop/switch region; other site
697329005913	Smr domain; Region: Smr; pfam01713
697329005914	DNA repair protein RecO; Region: reco; TIGR00613
697329005915	Recombination protein O N terminal; Region: RecO_N; pfam11967
697329005916	Recombination protein O C terminal; Region: RecO_C; pfam02565
697329005917	GTPase Era; Reviewed; Region: era; PRK00089
697329005918	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
697329005919	G1 box; other site
697329005920	GTP/Mg2+ binding site [chemical binding]; other site
697329005921	Switch I region; other site
697329005922	G2 box; other site
697329005923	Switch II region; other site
697329005924	G3 box; other site
697329005925	G4 box; other site
697329005926	G5 box; other site
697329005927	KH domain; Region: KH_2; pfam07650
697329005928	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329005929	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329005930	Coenzyme A binding pocket [chemical binding]; other site
697329005931	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
697329005932	nudix motif; other site
697329005933	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
697329005934	metal-binding heat shock protein; Provisional; Region: PRK00016
697329005935	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
697329005936	PhoH-like protein; Region: PhoH; pfam02562
697329005937	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
697329005938	Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898
697329005939	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
697329005940	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
697329005941	Stage III sporulation protein D; Region: SpoIIID; pfam12116
697329005942	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
697329005943	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329005944	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
697329005945	ligand binding site [chemical binding]; other site
697329005946	dimerization interface [polypeptide binding]; other site
697329005947	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329005948	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329005949	metal binding site [ion binding]; metal-binding site
697329005950	active site
697329005951	I-site; other site
697329005952	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
697329005953	CoenzymeA binding site [chemical binding]; other site
697329005954	subunit interaction site [polypeptide binding]; other site
697329005955	PHB binding site; other site
697329005956	Nitroreductase family; Region: Nitroreductase; pfam00881
697329005957	FMN binding site [chemical binding]; other site
697329005958	dimer interface [polypeptide binding]; other site
697329005959	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
697329005960	dimer interface [polypeptide binding]; other site
697329005961	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329005962	TfoX N-terminal domain; Region: TfoX_N; pfam04993
697329005963	glycogen synthase; Provisional; Region: glgA; PRK00654
697329005964	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
697329005965	ADP-binding pocket [chemical binding]; other site
697329005966	homodimer interface [polypeptide binding]; other site
697329005967	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
697329005968	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
697329005969	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329005970	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329005971	Coenzyme A binding pocket [chemical binding]; other site
697329005972	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
697329005973	ATP cone domain; Region: ATP-cone; pfam03477
697329005974	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
697329005975	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
697329005976	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
697329005977	ligand binding site [chemical binding]; other site
697329005978	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
697329005979	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
697329005980	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
697329005981	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
697329005982	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
697329005983	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
697329005984	active site
697329005985	metal binding site [ion binding]; metal-binding site
697329005986	Chromate transporter; Region: Chromate_transp; pfam02417
697329005987	Chromate transporter; Region: Chromate_transp; pfam02417
697329005988	DNA polymerase IV; Reviewed; Region: PRK03103
697329005989	Y-family of DNA polymerases; Region: PolY; cl12025
697329005990	active site
697329005991	DNA binding site [nucleotide binding]
697329005992	comF family protein; Region: comF; TIGR00201
697329005993	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329005994	active site
697329005995	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
697329005996	active site
697329005997	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329005998	metal binding site [ion binding]; metal-binding site
697329005999	active site
697329006000	I-site; other site
697329006001	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329006002	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
697329006003	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329006004	Coenzyme A binding pocket [chemical binding]; other site
697329006005	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
697329006006	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329006007	Coenzyme A binding pocket [chemical binding]; other site
697329006008	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
697329006009	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
697329006010	Walker A/P-loop; other site
697329006011	ATP binding site [chemical binding]; other site
697329006012	Q-loop/lid; other site
697329006013	ABC transporter signature motif; other site
697329006014	Walker B; other site
697329006015	D-loop; other site
697329006016	H-loop/switch region; other site
697329006017	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329006018	dimer interface [polypeptide binding]; other site
697329006019	conserved gate region; other site
697329006020	putative PBP binding loops; other site
697329006021	ABC-ATPase subunit interface; other site
697329006022	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
697329006023	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
697329006024	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
697329006025	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
697329006026	active site
697329006027	dimer interface [polypeptide binding]; other site
697329006028	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
697329006029	Ligand Binding Site [chemical binding]; other site
697329006030	Molecular Tunnel; other site
697329006031	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
697329006032	ATP cone domain; Region: ATP-cone; pfam03477
697329006033	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
697329006034	Class III ribonucleotide reductase; Region: RNR_III; cd01675
697329006035	active site
697329006036	Zn binding site [ion binding]; other site
697329006037	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
697329006038	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329006039	FeS/SAM binding site; other site
697329006040	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
697329006041	active site
697329006042	putative catalytic site [active]
697329006043	DNA binding site [nucleotide binding]
697329006044	putative phosphate binding site [ion binding]; other site
697329006045	metal binding site A [ion binding]; metal-binding site
697329006046	AP binding site [nucleotide binding]; other site
697329006047	metal binding site B [ion binding]; metal-binding site
697329006048	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329006049	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
697329006050	active site
697329006051	metal binding site [ion binding]; metal-binding site
697329006052	aspartyl-tRNA synthetase; Provisional; Region: aspC; PRK05159
697329006053	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
697329006054	Dimer interface [polypeptide binding]; other site
697329006055	anticodon binding site; other site
697329006056	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
697329006057	motif 1; other site
697329006058	dimer interface [polypeptide binding]; other site
697329006059	active site
697329006060	motif 2; other site
697329006061	motif 3; other site
697329006062	CAAX protease self-immunity; Region: Abi; pfam02517
697329006063	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329006064	non-specific DNA binding site [nucleotide binding]; other site
697329006065	salt bridge; other site
697329006066	sequence-specific DNA binding site [nucleotide binding]; other site
697329006067	CAAX protease self-immunity; Region: Abi; pfam02517
697329006068	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329006069	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329006070	active site
697329006071	phosphorylation site [posttranslational modification]
697329006072	intermolecular recognition site; other site
697329006073	dimerization interface [polypeptide binding]; other site
697329006074	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329006075	DNA binding site [nucleotide binding]
697329006076	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329006077	dimer interface [polypeptide binding]; other site
697329006078	phosphorylation site [posttranslational modification]
697329006079	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329006080	ATP binding site [chemical binding]; other site
697329006081	Mg2+ binding site [ion binding]; other site
697329006082	G-X-G motif; other site
697329006083	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
697329006084	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
697329006085	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
697329006086	PhoU domain; Region: PhoU; pfam01895
697329006087	PhoU domain; Region: PhoU; pfam01895
697329006088	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
697329006089	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
697329006090	dimer interface [polypeptide binding]; other site
697329006091	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329006092	catalytic residue [active]
697329006093	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
697329006094	metal ion-dependent adhesion site (MIDAS); other site
697329006095	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
697329006096	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
697329006097	motif 1; other site
697329006098	active site
697329006099	motif 2; other site
697329006100	motif 3; other site
697329006101	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
697329006102	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
697329006103	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
697329006104	nucleotide binding site/active site [active]
697329006105	HIT family signature motif; other site
697329006106	catalytic residue [active]
697329006107	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
697329006108	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
697329006109	Competence protein; Region: Competence; pfam03772
697329006110	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
697329006111	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
697329006112	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
697329006113	active site
697329006114	metal binding site [ion binding]; metal-binding site
697329006115	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
697329006116	MBOAT, membrane-bound O-acyltransferase family; Region: MBOAT; cl00738
697329006117	DHHW protein; Region: DHHW; pfam14286
697329006118	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329006119	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329006120	catalytic residues [active]
697329006121	catalytic nucleophile [active]
697329006122	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
697329006123	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
697329006124	DNA binding site [nucleotide binding]
697329006125	active site
697329006126	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
697329006127	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
697329006128	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329006129	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
697329006130	generic binding surface II; other site
697329006131	generic binding surface I; other site
697329006132	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from archaea and bacteria; Region: NTP-PPase_COG4997; cd11532
697329006133	metal binding site [ion binding]; metal-binding site
697329006134	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
697329006135	Domain of unknown function (DUF4298); Region: DUF4298; pfam14131
697329006136	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329006137	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
697329006138	DNA binding site [nucleotide binding]
697329006139	domain linker motif; other site
697329006140	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
697329006141	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
697329006142	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
697329006143	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
697329006144	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
697329006145	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
697329006146	substrate binding site [chemical binding]; other site
697329006147	active site
697329006148	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
697329006149	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329006150	putative sugar binding sites [chemical binding]; other site
697329006151	Q-X-W motif; other site
697329006152	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cl15820
697329006153	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329006154	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329006155	ligand binding site [chemical binding]; other site
697329006156	dimerization interface [polypeptide binding]; other site
697329006157	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329006158	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
697329006159	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
697329006160	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329006161	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329006162	Methyltransferase domain; Region: Methyltransf_31; pfam13847
697329006163	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329006164	S-adenosylmethionine binding site [chemical binding]; other site
697329006165	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
697329006166	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
697329006167	transmembrane helices; other site
697329006168	Transposase, Mutator family; Region: Transposase_mut; pfam00872
697329006169	MULE transposase domain; Region: MULE; pfam10551
697329006170	short chain dehydrogenase; Provisional; Region: PRK06940
697329006171	classical (c) SDRs; Region: SDR_c; cd05233
697329006172	NAD(P) binding site [chemical binding]; other site
697329006173	active site
697329006174	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
697329006175	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
697329006176	putative NADP binding site [chemical binding]; other site
697329006177	putative substrate binding site [chemical binding]; other site
697329006178	active site
697329006179	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329006180	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329006181	active site
697329006182	phosphorylation site [posttranslational modification]
697329006183	intermolecular recognition site; other site
697329006184	dimerization interface [polypeptide binding]; other site
697329006185	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329006186	DNA binding site [nucleotide binding]
697329006187	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329006188	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
697329006189	dimerization interface [polypeptide binding]; other site
697329006190	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329006191	dimer interface [polypeptide binding]; other site
697329006192	phosphorylation site [posttranslational modification]
697329006193	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329006194	ATP binding site [chemical binding]; other site
697329006195	Mg2+ binding site [ion binding]; other site
697329006196	G-X-G motif; other site
697329006197	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329006198	Zn2+ binding site [ion binding]; other site
697329006199	Mg2+ binding site [ion binding]; other site
697329006200	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
697329006201	dihydropteroate synthase; Region: DHPS; TIGR01496
697329006202	substrate binding pocket [chemical binding]; other site
697329006203	dimer interface [polypeptide binding]; other site
697329006204	inhibitor binding site; inhibition site
697329006205	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
697329006206	homooctamer interface [polypeptide binding]; other site
697329006207	active site
697329006208	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
697329006209	catalytic center binding site [active]
697329006210	ATP binding site [chemical binding]; other site
697329006211	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
697329006212	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
697329006213	folate binding site [chemical binding]; other site
697329006214	NADP+ binding site [chemical binding]; other site
697329006215	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
697329006216	Phosphopantetheine attachment site; Region: PP-binding; cl09936
697329006217	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
697329006218	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
697329006219	substrate binding site [chemical binding]; other site
697329006220	oxyanion hole (OAH) forming residues; other site
697329006221	trimer interface [polypeptide binding]; other site
697329006222	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
697329006223	active site
697329006224	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
697329006225	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
697329006226	substrate binding site [chemical binding]; other site
697329006227	oxyanion hole (OAH) forming residues; other site
697329006228	trimer interface [polypeptide binding]; other site
697329006229	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK08293
697329006230	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
697329006231	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
697329006232	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
697329006233	dimer interface [polypeptide binding]; other site
697329006234	active site
697329006235	macrophage migration inhibition factor-like protein; Provisional; Region: PTZ00397
697329006236	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
697329006237	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
697329006238	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329006239	acyl-activating enzyme (AAE) consensus motif; other site
697329006240	AMP binding site [chemical binding]; other site
697329006241	active site
697329006242	CoA binding site [chemical binding]; other site
697329006243	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
697329006244	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
697329006245	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
697329006246	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
697329006247	Walker A/P-loop; other site
697329006248	ATP binding site [chemical binding]; other site
697329006249	Q-loop/lid; other site
697329006250	ABC transporter signature motif; other site
697329006251	Walker B; other site
697329006252	D-loop; other site
697329006253	H-loop/switch region; other site
697329006254	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
697329006255	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
697329006256	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
697329006257	Transposase; Region: DEDD_Tnp_IS110; pfam01548
697329006258	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
697329006259	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329006260	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
697329006261	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329006262	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
697329006263	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
697329006264	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
697329006265	dimer interface [polypeptide binding]; other site
697329006266	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329006267	catalytic residue [active]
697329006268	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cd00562
697329006269	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
697329006270	substrate binding site [chemical binding]; other site
697329006271	active site
697329006272	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329006273	Ricin-type beta-trefoil; Region: RICIN; smart00458
697329006274	putative sugar binding sites [chemical binding]; other site
697329006275	Q-X-W motif; other site
697329006276	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329006277	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329006278	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329006279	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329006280	ligand binding site [chemical binding]; other site
697329006281	dimerization interface [polypeptide binding]; other site
697329006282	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329006283	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329006284	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329006285	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329006286	ligand binding site [chemical binding]; other site
697329006287	dimerization interface [polypeptide binding]; other site
697329006288	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
697329006289	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
697329006290	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329006291	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
697329006292	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
697329006293	Peptidase family U32; Region: Peptidase_U32; pfam01136
697329006294	YceG-like family; Region: YceG; pfam02618
697329006295	proteins similar to Escherichia coli yceG; Region: yceG_like; cl17666
697329006296	dimerization interface [polypeptide binding]; other site
697329006297	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
697329006298	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
697329006299	DJ-1 family protein; Region: not_thiJ; TIGR01383
697329006300	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
697329006301	conserved cys residue [active]
697329006302	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
697329006303	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
697329006304	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
697329006305	TMP-binding site; other site
697329006306	ATP-binding site [chemical binding]; other site
697329006307	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
697329006308	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
697329006309	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
697329006310	Walker A/P-loop; other site
697329006311	ATP binding site [chemical binding]; other site
697329006312	Q-loop/lid; other site
697329006313	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
697329006314	ABC transporter signature motif; other site
697329006315	Walker B; other site
697329006316	D-loop; other site
697329006317	H-loop/switch region; other site
697329006318	Arginine repressor [Transcription]; Region: ArgR; COG1438
697329006319	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
697329006320	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
697329006321	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
697329006322	ATP-NAD kinase; Region: NAD_kinase; pfam01513
697329006323	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
697329006324	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329006325	RNA binding surface [nucleotide binding]; other site
697329006326	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
697329006327	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
697329006328	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
697329006329	TPP-binding site; other site
697329006330	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
697329006331	PYR/PP interface [polypeptide binding]; other site
697329006332	dimer interface [polypeptide binding]; other site
697329006333	TPP binding site [chemical binding]; other site
697329006334	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
697329006335	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
697329006336	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
697329006337	substrate binding pocket [chemical binding]; other site
697329006338	chain length determination region; other site
697329006339	substrate-Mg2+ binding site; other site
697329006340	catalytic residues [active]
697329006341	aspartate-rich region 1; other site
697329006342	active site lid residues [active]
697329006343	aspartate-rich region 2; other site
697329006344	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
697329006345	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
697329006346	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
697329006347	generic binding surface I; other site
697329006348	generic binding surface II; other site
697329006349	Metal-dependent proteases with possible chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: QRI7; COG0533
697329006350	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
697329006351	putative RNA binding site [nucleotide binding]; other site
697329006352	Asp23 family; Region: Asp23; pfam03780
697329006353	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
697329006354	Ubiquitin; Region: Ubiquitin; cd01803
697329006355	Ubiquitin family; Region: ubiquitin; pfam00240
697329006356	Ubq - E2 interaction site; other site
697329006357	Ubq - UCH interaction site; other site
697329006358	Ubq - CUE interaction site; other site
697329006359	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329006360	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329006361	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329006362	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329006363	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329006364	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329006365	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
697329006366	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
697329006367	PYR/PP interface [polypeptide binding]; other site
697329006368	dimer interface [polypeptide binding]; other site
697329006369	TPP binding site [chemical binding]; other site
697329006370	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
697329006371	transketolase; Reviewed; Region: PRK05899
697329006372	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
697329006373	TPP-binding site [chemical binding]; other site
697329006374	dimer interface [polypeptide binding]; other site
697329006375	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329006376	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
697329006377	active site
697329006378	motif I; other site
697329006379	motif II; other site
697329006380	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329006381	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
697329006382	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329006383	RNA binding surface [nucleotide binding]; other site
697329006384	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
697329006385	active site
697329006386	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
697329006387	DivIVA protein; Region: DivIVA; pfam05103
697329006388	DivIVA domain; Region: DivI1A_domain; TIGR03544
697329006389	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
697329006390	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329006391	RNA binding surface [nucleotide binding]; other site
697329006392	Protein of unknown function (DUF552); Region: DUF552; pfam04472
697329006393	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
697329006394	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
697329006395	catalytic residue [active]
697329006396	HlyD family secretion protein; Region: HlyD_2; pfam12700
697329006397	putative membrane fusion protein; Region: TIGR02828
697329006398	bacterial Hfq-like; Region: Hfq; cd01716
697329006399	hexamer interface [polypeptide binding]; other site
697329006400	Sm1 motif; other site
697329006401	RNA binding site [nucleotide binding]; other site
697329006402	Sm2 motif; other site
697329006403	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
697329006404	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
697329006405	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
697329006406	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329006407	ATP binding site [chemical binding]; other site
697329006408	Mg2+ binding site [ion binding]; other site
697329006409	G-X-G motif; other site
697329006410	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
697329006411	ATP binding site [chemical binding]; other site
697329006412	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
697329006413	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
697329006414	MutS domain I; Region: MutS_I; pfam01624
697329006415	MutS domain II; Region: MutS_II; pfam05188
697329006416	MutS domain III; Region: MutS_III; pfam05192
697329006417	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
697329006418	Walker A/P-loop; other site
697329006419	ATP binding site [chemical binding]; other site
697329006420	Q-loop/lid; other site
697329006421	ABC transporter signature motif; other site
697329006422	Walker B; other site
697329006423	D-loop; other site
697329006424	H-loop/switch region; other site
697329006425	Protein of unknown function (DUF964); Region: DUF964; cl01483
697329006426	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14328
697329006427	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
697329006428	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329006429	FeS/SAM binding site; other site
697329006430	TRAM domain; Region: TRAM; pfam01938
697329006431	SCIFF radical SAM maturase; Region: rSAM_six_Cys; TIGR03974
697329006432	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329006433	FeS/SAM binding site; other site
697329006434	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
697329006435	Protein of unknown function (DUF4001); Region: DUF4001; cl14848
697329006436	putative membrane protein, TIGR04086 family; Region: TIGR04086_membr
697329006437	Preprotein translocase subunit; Region: YajC; pfam02699
697329006438	putative oxidoreductase; Provisional; Region: PRK12831
697329006439	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
697329006440	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
697329006441	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
697329006442	ferredoxin-NADP(+) reductase subunit alpha; Reviewed; Region: PRK06222
697329006443	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
697329006444	FAD binding pocket [chemical binding]; other site
697329006445	FAD binding motif [chemical binding]; other site
697329006446	phosphate binding motif [ion binding]; other site
697329006447	beta-alpha-beta structure motif; other site
697329006448	NAD binding pocket [chemical binding]; other site
697329006449	Iron coordination center [ion binding]; other site
697329006450	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
697329006451	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
697329006452	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
697329006453	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
697329006454	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
697329006455	Immunity protein Imm1; Region: Imm1; pfam14430
697329006456	8-oxoguanine DNA glycosylase, N-terminal domain; Region: OGG_N; pfam07934
697329006457	8-oxoguanine DNA-glycosylase (ogg); Region: ogg; TIGR00588
697329006458	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
697329006459	minor groove reading motif; other site
697329006460	helix-hairpin-helix signature motif; other site
697329006461	substrate binding pocket [chemical binding]; other site
697329006462	active site
697329006463	Protease prsW family; Region: PrsW-protease; pfam13367
697329006464	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329006465	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
697329006466	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
697329006467	Leucine carboxyl methyltransferase; Region: LCM; pfam04072
697329006468	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
697329006469	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329006470	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
697329006471	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
697329006472	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
697329006473	Low molecular weight phosphatase family; Region: LMWPc; cd00115
697329006474	active site
697329006475	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
697329006476	Zinc dependent phospholipase C (alpha toxin); Region: Zn_dep_PLPC; cd11009
697329006477	Zn binding site [ion binding]; other site
697329006478	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
697329006479	CotH protein; Region: CotH; pfam08757
697329006480	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329006481	Coenzyme A binding pocket [chemical binding]; other site
697329006482	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329006483	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329006484	Walker A/P-loop; other site
697329006485	ATP binding site [chemical binding]; other site
697329006486	Q-loop/lid; other site
697329006487	ABC transporter signature motif; other site
697329006488	Walker B; other site
697329006489	D-loop; other site
697329006490	H-loop/switch region; other site
697329006491	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
697329006492	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329006493	FtsX-like permease family; Region: FtsX; pfam02687
697329006494	Domain of unknown function (DUF4418); Region: DUF4418; pfam14387
697329006495	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
697329006496	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
697329006497	Walker A/P-loop; other site
697329006498	ATP binding site [chemical binding]; other site
697329006499	Q-loop/lid; other site
697329006500	ABC transporter signature motif; other site
697329006501	Walker B; other site
697329006502	D-loop; other site
697329006503	H-loop/switch region; other site
697329006504	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
697329006505	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329006506	dimer interface [polypeptide binding]; other site
697329006507	conserved gate region; other site
697329006508	putative PBP binding loops; other site
697329006509	ABC-ATPase subunit interface; other site
697329006510	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
697329006511	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
697329006512	substrate binding pocket [chemical binding]; other site
697329006513	membrane-bound complex binding site; other site
697329006514	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329006515	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329006516	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329006517	Walker A/P-loop; other site
697329006518	ATP binding site [chemical binding]; other site
697329006519	Q-loop/lid; other site
697329006520	ABC transporter signature motif; other site
697329006521	Walker B; other site
697329006522	D-loop; other site
697329006523	H-loop/switch region; other site
697329006524	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329006525	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329006526	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329006527	Walker A/P-loop; other site
697329006528	ATP binding site [chemical binding]; other site
697329006529	Q-loop/lid; other site
697329006530	ABC transporter signature motif; other site
697329006531	Walker B; other site
697329006532	D-loop; other site
697329006533	H-loop/switch region; other site
697329006534	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
697329006535	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329006536	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
697329006537	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
697329006538	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
697329006539	Homoserine O-succinyltransferase; Region: HTS; pfam04204
697329006540	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
697329006541	proposed active site lysine [active]
697329006542	conserved cys residue [active]
697329006543	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329006544	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329006545	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
697329006546	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; cl01757
697329006547	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
697329006548	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
697329006549	dimer interface [polypeptide binding]; other site
697329006550	active site
697329006551	glycine-pyridoxal phosphate binding site [chemical binding]; other site
697329006552	folate binding site [chemical binding]; other site
697329006553	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
697329006554	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
697329006555	AP (apurinic/apyrimidinic) site pocket; other site
697329006556	Metal-binding active site; metal-binding site
697329006557	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329006558	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329006559	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329006560	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329006561	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329006562	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329006563	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329006564	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
697329006565	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
697329006566	phosphate binding site [ion binding]; other site
697329006567	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
697329006568	homotrimer interaction site [polypeptide binding]; other site
697329006569	putative active site [active]
697329006570	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
697329006571	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329006572	active site
697329006573	DNA binding site [nucleotide binding]
697329006574	Int/Topo IB signature motif; other site
697329006575	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
697329006576	Predicted nucleotidyltransferase; Region: Nuc-transf; cl01417
697329006577	Predicted nucleotidyltransferase; Region: Nuc-transf; cl01417
697329006578	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
697329006579	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme; Region: E_set_GDE_N; cd11234
697329006580	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
697329006581	active site
697329006582	catalytic site [active]
697329006583	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
697329006584	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
697329006585	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329006586	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
697329006587	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
697329006588	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
697329006589	Flavin Reductases; Region: FlaRed; cl00801
697329006590	argininosuccinate synthase; Provisional; Region: PRK13820
697329006591	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
697329006592	ANP binding site [chemical binding]; other site
697329006593	Substrate Binding Site II [chemical binding]; other site
697329006594	Substrate Binding Site I [chemical binding]; other site
697329006595	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
697329006596	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
697329006597	argininosuccinate lyase; Provisional; Region: PRK00855
697329006598	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
697329006599	active sites [active]
697329006600	tetramer interface [polypeptide binding]; other site
697329006601	N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863
697329006602	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
697329006603	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
697329006604	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
697329006605	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
697329006606	heterotetramer interface [polypeptide binding]; other site
697329006607	active site pocket [active]
697329006608	cleavage site
697329006609	TraX protein; Region: TraX; pfam05857
697329006610	conjugal transfer protein TrbP; Provisional; Region: PRK13882
697329006611	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
697329006612	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
697329006613	feedback inhibition sensing region; other site
697329006614	homohexameric interface [polypeptide binding]; other site
697329006615	nucleotide binding site [chemical binding]; other site
697329006616	N-acetyl-L-glutamate binding site [chemical binding]; other site
697329006617	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329006618	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329006619	acetylornithine aminotransferase; Provisional; Region: PRK02627
697329006620	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
697329006621	inhibitor-cofactor binding pocket; inhibition site
697329006622	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329006623	catalytic residue [active]
697329006624	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329006625	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329006626	Coenzyme A binding pocket [chemical binding]; other site
697329006627	ornithine carbamoyltransferase; Provisional; Region: PRK00779
697329006628	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
697329006629	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
697329006630	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329006631	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329006632	non-specific DNA binding site [nucleotide binding]; other site
697329006633	salt bridge; other site
697329006634	sequence-specific DNA binding site [nucleotide binding]; other site
697329006635	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
697329006636	aspartate kinase; Reviewed; Region: PRK09034
697329006637	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
697329006638	nucleotide binding site [chemical binding]; other site
697329006639	substrate binding site [chemical binding]; other site
697329006640	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
697329006641	allosteric regulatory residue; other site
697329006642	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
697329006643	TraB family; Region: TraB; pfam01963
697329006644	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
697329006645	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
697329006646	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
697329006647	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
697329006648	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
697329006649	glycogen branching enzyme; Provisional; Region: PRK12313
697329006650	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
697329006651	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
697329006652	active site
697329006653	catalytic site [active]
697329006654	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
697329006655	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
697329006656	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
697329006657	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
697329006658	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
697329006659	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
697329006660	2-isopropylmalate synthase; Validated; Region: PRK03739
697329006661	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
697329006662	active site
697329006663	catalytic residues [active]
697329006664	metal binding site [ion binding]; metal-binding site
697329006665	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
697329006666	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329006667	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
697329006668	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
697329006669	Soluble P-type ATPase [General function prediction only]; Region: COG4087
697329006670	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329006671	S-adenosylmethionine binding site [chemical binding]; other site
697329006672	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
697329006673	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329006674	Alpha amylase catalytic domain found in eukaryotic and bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_euk_bac_CMD_like; cd11353
697329006675	active site
697329006676	catalytic site [active]
697329006677	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
697329006678	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
697329006679	metal binding site [ion binding]; metal-binding site
697329006680	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
697329006681	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
697329006682	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329006683	Coenzyme A binding pocket [chemical binding]; other site
697329006684	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
697329006685	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
697329006686	substrate binding site [chemical binding]; other site
697329006687	glutamase interaction surface [polypeptide binding]; other site
697329006688	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
697329006689	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329006690	S-adenosylmethionine binding site [chemical binding]; other site
697329006691	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
697329006692	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
697329006693	putative active site [active]
697329006694	oxyanion strand; other site
697329006695	catalytic triad [active]
697329006696	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
697329006697	putative active site pocket [active]
697329006698	4-fold oligomerization interface [polypeptide binding]; other site
697329006699	metal binding residues [ion binding]; metal-binding site
697329006700	3-fold/trimer interface [polypeptide binding]; other site
697329006701	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
697329006702	NodB motif; other site
697329006703	active site
697329006704	catalytic site [active]
697329006705	metal binding site [ion binding]; metal-binding site
697329006706	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
697329006707	histidinol dehydrogenase; Region: hisD; TIGR00069
697329006708	NAD binding site [chemical binding]; other site
697329006709	dimerization interface [polypeptide binding]; other site
697329006710	product binding site; other site
697329006711	substrate binding site [chemical binding]; other site
697329006712	zinc binding site [ion binding]; other site
697329006713	catalytic residues [active]
697329006714	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
697329006715	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
697329006716	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292
697329006717	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
697329006718	dimer interface [polypeptide binding]; other site
697329006719	motif 1; other site
697329006720	active site
697329006721	motif 2; other site
697329006722	motif 3; other site
697329006723	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
697329006724	DNA polymerase III PolC; Validated; Region: polC; PRK00448
697329006725	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
697329006726	generic binding surface II; other site
697329006727	generic binding surface I; other site
697329006728	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
697329006729	active site
697329006730	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
697329006731	active site
697329006732	catalytic site [active]
697329006733	substrate binding site [chemical binding]; other site
697329006734	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
697329006735	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
697329006736	GcpE protein; Region: GcpE; pfam04551
697329006737	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
697329006738	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
697329006739	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
697329006740	active site
697329006741	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
697329006742	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
697329006743	putative substrate binding region [chemical binding]; other site
697329006744	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
697329006745	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
697329006746	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
697329006747	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
697329006748	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
697329006749	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
697329006750	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
697329006751	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
697329006752	catalytic residue [active]
697329006753	putative FPP diphosphate  binding site; other site
697329006754	putative FPP binding hydrophobic cleft; other site
697329006755	dimer interface [polypeptide binding]; other site
697329006756	putative IPP diphosphate binding site; other site
697329006757	ribosome recycling factor; Reviewed; Region: frr; PRK00083
697329006758	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
697329006759	hinge region; other site
697329006760	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
697329006761	putative nucleotide binding site [chemical binding]; other site
697329006762	uridine monophosphate binding site [chemical binding]; other site
697329006763	homohexameric interface [polypeptide binding]; other site
697329006764	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
697329006765	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
697329006766	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
697329006767	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
697329006768	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
697329006769	GTP-binding protein Der; Reviewed; Region: PRK00093
697329006770	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
697329006771	G1 box; other site
697329006772	GTP/Mg2+ binding site [chemical binding]; other site
697329006773	Switch I region; other site
697329006774	G2 box; other site
697329006775	Switch II region; other site
697329006776	G3 box; other site
697329006777	G4 box; other site
697329006778	G5 box; other site
697329006779	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
697329006780	G1 box; other site
697329006781	GTP/Mg2+ binding site [chemical binding]; other site
697329006782	Switch I region; other site
697329006783	G2 box; other site
697329006784	G3 box; other site
697329006785	Switch II region; other site
697329006786	G4 box; other site
697329006787	G5 box; other site
697329006788	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
697329006789	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
697329006790	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
697329006791	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
697329006792	active site
697329006793	dimer interface [polypeptide binding]; other site
697329006794	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
697329006795	dimer interface [polypeptide binding]; other site
697329006796	active site
697329006797	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
697329006798	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
697329006799	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
697329006800	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329006801	metal binding site [ion binding]; metal-binding site
697329006802	active site
697329006803	I-site; other site
697329006804	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329006805	H+ Antiporter protein; Region: 2A0121; TIGR00900
697329006806	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
697329006807	putative substrate translocation pore; other site
697329006808	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329006809	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329006810	Walker A/P-loop; other site
697329006811	ATP binding site [chemical binding]; other site
697329006812	Q-loop/lid; other site
697329006813	ABC transporter signature motif; other site
697329006814	Walker B; other site
697329006815	D-loop; other site
697329006816	H-loop/switch region; other site
697329006817	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329006818	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329006819	non-specific DNA binding site [nucleotide binding]; other site
697329006820	salt bridge; other site
697329006821	sequence-specific DNA binding site [nucleotide binding]; other site
697329006822	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
697329006823	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329006824	Walker A/P-loop; other site
697329006825	ATP binding site [chemical binding]; other site
697329006826	Q-loop/lid; other site
697329006827	ABC transporter signature motif; other site
697329006828	Walker B; other site
697329006829	D-loop; other site
697329006830	H-loop/switch region; other site
697329006831	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
697329006832	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
697329006833	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
697329006834	DEAD-like helicases superfamily; Region: DEXDc; smart00487
697329006835	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329006836	ATP binding site [chemical binding]; other site
697329006837	putative Mg++ binding site [ion binding]; other site
697329006838	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329006839	nucleotide binding region [chemical binding]; other site
697329006840	ATP-binding site [chemical binding]; other site
697329006841	P-loop Domain of unknown function (DUF2791); Region: DUF2791; pfam10923
697329006842	AAA ATPase domain; Region: AAA_16; pfam13191
697329006843	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
697329006844	thiS-thiF/thiG interaction site; other site
697329006845	thiamine biosynthesis protein ThiF; Provisional; Region: PRK08644
697329006846	E1_ThiF_like. Member of superfamily of activating enzymes (E1) of the ubiquitin-like proteins. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like substrate, on...; Region: E1_ThiF_like; cd01487
697329006847	putative ATP binding site [chemical binding]; other site
697329006848	putative substrate interface [chemical binding]; other site
697329006849	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
697329006850	ThiS interaction site; other site
697329006851	putative active site [active]
697329006852	tetramer interface [polypeptide binding]; other site
697329006853	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
697329006854	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329006855	FeS/SAM binding site; other site
697329006856	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
697329006857	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
697329006858	thiamine phosphate binding site [chemical binding]; other site
697329006859	active site
697329006860	pyrophosphate binding site [ion binding]; other site
697329006861	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
697329006862	thiamine phosphate binding site [chemical binding]; other site
697329006863	active site
697329006864	pyrophosphate binding site [ion binding]; other site
697329006865	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
697329006866	dimer interface [polypeptide binding]; other site
697329006867	substrate binding site [chemical binding]; other site
697329006868	ATP binding site [chemical binding]; other site
697329006869	thiamine biosynthesis protein ThiC; Provisional; Region: PRK13352
697329006870	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
697329006871	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
697329006872	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
697329006873	Active site serine [active]
697329006874	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
697329006875	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
697329006876	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
697329006877	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329006878	Walker A/P-loop; other site
697329006879	ATP binding site [chemical binding]; other site
697329006880	Q-loop/lid; other site
697329006881	ABC transporter signature motif; other site
697329006882	Walker B; other site
697329006883	D-loop; other site
697329006884	H-loop/switch region; other site
697329006885	WYL domain; Region: WYL; pfam13280
697329006886	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
697329006887	WYL domain; Region: WYL; pfam13280
697329006888	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
697329006889	hypothetical protein; Reviewed; Region: PRK09588
697329006890	Domain of unknown function (DUF2828); Region: DUF2828; pfam11443
697329006891	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329006892	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329006893	dimer interface [polypeptide binding]; other site
697329006894	phosphorylation site [posttranslational modification]
697329006895	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329006896	ATP binding site [chemical binding]; other site
697329006897	Mg2+ binding site [ion binding]; other site
697329006898	G-X-G motif; other site
697329006899	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329006900	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329006901	active site
697329006902	phosphorylation site [posttranslational modification]
697329006903	intermolecular recognition site; other site
697329006904	dimerization interface [polypeptide binding]; other site
697329006905	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329006906	DNA binding site [nucleotide binding]
697329006907	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
697329006908	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
697329006909	substrate binding site [chemical binding]; other site
697329006910	ATP binding site [chemical binding]; other site
697329006911	Glucuronate isomerase; Region: UxaC; pfam02614
697329006912	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
697329006913	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
697329006914	galactarate dehydratase; Region: galactar-dH20; TIGR03248
697329006915	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
697329006916	altronate oxidoreductase; Provisional; Region: PRK03643
697329006917	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
697329006918	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
697329006919	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
697329006920	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
697329006921	Walker A/P-loop; other site
697329006922	ATP binding site [chemical binding]; other site
697329006923	Q-loop/lid; other site
697329006924	ABC transporter signature motif; other site
697329006925	Walker B; other site
697329006926	D-loop; other site
697329006927	H-loop/switch region; other site
697329006928	TOBE domain; Region: TOBE_2; pfam08402
697329006929	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
697329006930	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
697329006931	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
697329006932	DNA interaction; other site
697329006933	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
697329006934	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
697329006935	substrate binding site [chemical binding]; other site
697329006936	ATP binding site [chemical binding]; other site
697329006937	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
697329006938	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
697329006939	active site
697329006940	intersubunit interface [polypeptide binding]; other site
697329006941	catalytic residue [active]
697329006942	2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832
697329006943	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
697329006944	NADP binding site [chemical binding]; other site
697329006945	homodimer interface [polypeptide binding]; other site
697329006946	active site
697329006947	Predicted permeases [General function prediction only]; Region: COG0679
697329006948	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
697329006949	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
697329006950	NAD(P) binding site [chemical binding]; other site
697329006951	LDH/MDH dimer interface [polypeptide binding]; other site
697329006952	substrate binding site [chemical binding]; other site
697329006953	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
697329006954	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
697329006955	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
697329006956	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
697329006957	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
697329006958	Walker A/P-loop; other site
697329006959	ATP binding site [chemical binding]; other site
697329006960	Q-loop/lid; other site
697329006961	ABC transporter signature motif; other site
697329006962	Walker B; other site
697329006963	D-loop; other site
697329006964	H-loop/switch region; other site
697329006965	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
697329006966	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329006967	dimer interface [polypeptide binding]; other site
697329006968	conserved gate region; other site
697329006969	ABC-ATPase subunit interface; other site
697329006970	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
697329006971	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329006972	dimer interface [polypeptide binding]; other site
697329006973	conserved gate region; other site
697329006974	ABC-ATPase subunit interface; other site
697329006975	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
697329006976	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
697329006977	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
697329006978	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
697329006979	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329006980	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329006981	Pectinesterase; Region: Pectinesterase; pfam01095
697329006982	putative pectinesterase; Region: PLN02432; cl01911
697329006983	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329006984	Protein of unknown function (DUF3584); Region: DUF3584; pfam12128
697329006985	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; Region: Pro_isomerase; pfam00160
697329006986	active site
697329006987	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
697329006988	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
697329006989	active site
697329006990	HIGH motif; other site
697329006991	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
697329006992	KMSKS motif; other site
697329006993	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
697329006994	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
697329006995	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
697329006996	trimer interface [polypeptide binding]; other site
697329006997	active site
697329006998	substrate binding site [chemical binding]; other site
697329006999	CoA binding site [chemical binding]; other site
697329007000	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
697329007001	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
697329007002	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
697329007003	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329007004	FeS/SAM binding site; other site
697329007005	recombination regulator RecX; Reviewed; Region: recX; PRK00117
697329007006	recombinase A; Provisional; Region: recA; PRK09354
697329007007	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
697329007008	hexamer interface [polypeptide binding]; other site
697329007009	Walker A motif; other site
697329007010	ATP binding site [chemical binding]; other site
697329007011	Walker B motif; other site
697329007012	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329007013	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
697329007014	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329007015	S-adenosylmethionine binding site [chemical binding]; other site
697329007016	Protein of unknown function (DUF1385); Region: DUF1385; pfam07136
697329007017	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329007018	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
697329007019	dimerization interface [polypeptide binding]; other site
697329007020	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329007021	dimer interface [polypeptide binding]; other site
697329007022	phosphorylation site [posttranslational modification]
697329007023	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329007024	ATP binding site [chemical binding]; other site
697329007025	Mg2+ binding site [ion binding]; other site
697329007026	G-X-G motif; other site
697329007027	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329007028	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329007029	active site
697329007030	phosphorylation site [posttranslational modification]
697329007031	intermolecular recognition site; other site
697329007032	dimerization interface [polypeptide binding]; other site
697329007033	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329007034	DNA binding site [nucleotide binding]
697329007035	The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains.   LytC is composed of a...; Region: GH25_LytC-like; cd06414
697329007036	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
697329007037	active site
697329007038	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
697329007039	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
697329007040	Glycoprotease family; Region: Peptidase_M22; pfam00814
697329007041	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
697329007042	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
697329007043	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
697329007044	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
697329007045	Potassium binding sites [ion binding]; other site
697329007046	Cesium cation binding sites [ion binding]; other site
697329007047	dihydrodipicolinate reductase; Provisional; Region: PRK00048
697329007048	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
697329007049	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
697329007050	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
697329007051	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
697329007052	dimer interface [polypeptide binding]; other site
697329007053	active site
697329007054	catalytic residue [active]
697329007055	Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain; Region: MPP_AQ1575; cd07390
697329007056	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329007057	putative active site [active]
697329007058	putative metal binding site [ion binding]; other site
697329007059	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
697329007060	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
697329007061	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
697329007062	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
697329007063	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
697329007064	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329007065	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
697329007066	Protein of unknown function DUF58; Region: DUF58; pfam01882
697329007067	MoxR-like ATPases [General function prediction only]; Region: COG0714
697329007068	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329007069	Walker A motif; other site
697329007070	ATP binding site [chemical binding]; other site
697329007071	Walker B motif; other site
697329007072	arginine finger; other site
697329007073	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
697329007074	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329007075	S-adenosylmethionine binding site [chemical binding]; other site
697329007076	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
697329007077	active site
697329007078	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329007079	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329007080	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329007081	ligand binding site [chemical binding]; other site
697329007082	dimerization interface [polypeptide binding]; other site
697329007083	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329007084	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329007085	metal binding site [ion binding]; metal-binding site
697329007086	active site
697329007087	I-site; other site
697329007088	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329007089	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329007090	dimerization interface [polypeptide binding]; other site
697329007091	ligand binding site [chemical binding]; other site
697329007092	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329007093	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329007094	metal binding site [ion binding]; metal-binding site
697329007095	active site
697329007096	I-site; other site
697329007097	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329007098	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329007099	Walker A/P-loop; other site
697329007100	ATP binding site [chemical binding]; other site
697329007101	Q-loop/lid; other site
697329007102	ABC transporter signature motif; other site
697329007103	Walker B; other site
697329007104	D-loop; other site
697329007105	H-loop/switch region; other site
697329007106	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329007107	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329007108	ATP binding site [chemical binding]; other site
697329007109	Mg2+ binding site [ion binding]; other site
697329007110	G-X-G motif; other site
697329007111	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329007112	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329007113	active site
697329007114	phosphorylation site [posttranslational modification]
697329007115	intermolecular recognition site; other site
697329007116	dimerization interface [polypeptide binding]; other site
697329007117	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329007118	DNA binding site [nucleotide binding]
697329007119	FAD binding domain; Region: FAD_binding_2; pfam00890
697329007120	Predicted oxidoreductase [General function prediction only]; Region: COG3573
697329007121	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
697329007122	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
697329007123	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329007124	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329007125	catalytic residues [active]
697329007126	catalytic nucleophile [active]
697329007127	Recombinase; Region: Recombinase; pfam07508
697329007128	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329007129	Recombinase; Region: Recombinase; pfam07508
697329007130	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329007131	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329007132	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
697329007133	catalytic residues [active]
697329007134	catalytic nucleophile [active]
697329007135	Recombinase; Region: Recombinase; pfam07508
697329007136	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329007137	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
697329007138	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329007139	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329007140	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
697329007141	Mg binding site [ion binding]; other site
697329007142	nucleotide binding site [chemical binding]; other site
697329007143	putative protofilament interface [polypeptide binding]; other site
697329007144	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329007145	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329007146	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329007147	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329007148	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329007149	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329007150	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329007151	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329007152	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
697329007153	Catalytic site [active]
697329007154	GTPase subunit of restriction endonuclease [Defense mechanisms]; Region: McrB; COG1401
697329007155	Domain of unknown function (DUF2357); Region: DUF2357; pfam09823
697329007156	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
697329007157	Catalytic site [active]
697329007158	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329007159	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329007160	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329007161	metal binding site [ion binding]; metal-binding site
697329007162	active site
697329007163	I-site; other site
697329007164	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
697329007165	Protoglobin; Region: Protoglobin; pfam11563
697329007166	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329007167	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329007168	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
697329007169	Walker A/P-loop; other site
697329007170	ATP binding site [chemical binding]; other site
697329007171	Q-loop/lid; other site
697329007172	ABC transporter signature motif; other site
697329007173	Walker B; other site
697329007174	D-loop; other site
697329007175	H-loop/switch region; other site
697329007176	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
697329007177	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
697329007178	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329007179	Walker A/P-loop; other site
697329007180	ATP binding site [chemical binding]; other site
697329007181	Q-loop/lid; other site
697329007182	ABC transporter signature motif; other site
697329007183	Walker B; other site
697329007184	D-loop; other site
697329007185	H-loop/switch region; other site
697329007186	polyphosphate kinase; Provisional; Region: PRK05443
697329007187	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
697329007188	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
697329007189	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
697329007190	putative active site [active]
697329007191	catalytic site [active]
697329007192	Catalytic C-terminal domain, second repeat, of uncharacterized prokaryotic polyphosphate kinases; Region: PLDc_PPK1_C2_unchar; cd09169
697329007193	putative domain interface [polypeptide binding]; other site
697329007194	putative active site [active]
697329007195	catalytic site [active]
697329007196	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329007197	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
697329007198	AAA domain; Region: AAA_13; pfam13166
697329007199	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329007200	Coenzyme A binding pocket [chemical binding]; other site
697329007201	Probable chromatin-remodeling complex ATPase chain; Provisional; Region: PLN03142
697329007202	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
697329007203	NADH(P)-binding; Region: NAD_binding_10; pfam13460
697329007204	NAD binding site [chemical binding]; other site
697329007205	substrate binding site [chemical binding]; other site
697329007206	putative active site [active]
697329007207	Predicted transcriptional regulator [Transcription]; Region: COG1959
697329007208	Transcriptional regulator; Region: Rrf2; pfam02082
697329007209	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
697329007210	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
697329007211	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
697329007212	Macro domain, Unknown family 1. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases)...; Region: Macro_1; cd02906
697329007213	putative ADP-ribose binding site [chemical binding]; other site
697329007214	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
697329007215	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cd00296
697329007216	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329007217	Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a...; Region: SR_TndX_transposase; cd03770
697329007218	putative catalytic residues [active]
697329007219	catalytic nucleophile [active]
697329007220	Recombinase; Region: Recombinase; pfam07508
697329007221	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329007222	Domain of unknown function (DUF4368); Region: DUF4368; pfam14287
697329007223	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
697329007224	Tetratricopeptide repeat; Region: TPR_12; pfam13424
697329007225	binding surface
697329007226	TPR motif; other site
697329007227	Tetratricopeptide repeat; Region: TPR_12; pfam13424
697329007228	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329007229	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
697329007230	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
697329007231	Mg binding site [ion binding]; other site
697329007232	nucleotide binding site [chemical binding]; other site
697329007233	putative protofilament interface [polypeptide binding]; other site
697329007234	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
697329007235	non-specific DNA binding site [nucleotide binding]; other site
697329007236	salt bridge; other site
697329007237	sequence-specific DNA binding site [nucleotide binding]; other site
697329007238	DNA methylase; Region: N6_N4_Mtase; cl17433
697329007239	Methyltransferase domain; Region: Methyltransf_26; pfam13659
697329007240	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
697329007241	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
697329007242	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase; Region: PHP_HisPPase; cd07432
697329007243	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
697329007244	active site
697329007245	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329007246	ABC transporter signature motif; other site
697329007247	Walker B; other site
697329007248	D-loop; other site
697329007249	H-loop/switch region; other site
697329007250	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329007251	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329007252	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329007253	Aldo/keto reductases, related to diketogulonate reductase [General function prediction only]; Region: ARA1; COG0656
697329007254	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
697329007255	putative dimer interface [polypeptide binding]; other site
697329007256	catalytic triad [active]
697329007257	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
697329007258	nudix motif; other site
697329007259	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
697329007260	nudix motif; other site
697329007261	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
697329007262	nucleotide binding site/active site [active]
697329007263	HIT family signature motif; other site
697329007264	catalytic residue [active]
697329007265	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
697329007266	Domains similar to the eukaryotic reeler domain and bacterial cohesins; Region: Reeler_cohesin_like; cl14606
697329007267	glycerol kinase; Provisional; Region: glpK; PRK00047
697329007268	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
697329007269	N- and C-terminal domain interface [polypeptide binding]; other site
697329007270	active site
697329007271	MgATP binding site [chemical binding]; other site
697329007272	catalytic site [active]
697329007273	metal binding site [ion binding]; metal-binding site
697329007274	glycerol binding site [chemical binding]; other site
697329007275	homotetramer interface [polypeptide binding]; other site
697329007276	homodimer interface [polypeptide binding]; other site
697329007277	FBP binding site [chemical binding]; other site
697329007278	protein IIAGlc interface [polypeptide binding]; other site
697329007279	Stress responsive A/B Barrel Domain; Region: Dabb; pfam07876
697329007280	DNA repair protein RadA; Provisional; Region: PRK11823
697329007281	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
697329007282	Walker A motif/ATP binding site; other site
697329007283	ATP binding site [chemical binding]; other site
697329007284	Walker B motif; other site
697329007285	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
697329007286	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
697329007287	Protein of unknown function (DUF464); Region: DUF464; cl01080
697329007288	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
697329007289	GTPase CgtA; Reviewed; Region: obgE; PRK12297
697329007290	GTP1/OBG; Region: GTP1_OBG; pfam01018
697329007291	Obg GTPase; Region: Obg; cd01898
697329007292	G1 box; other site
697329007293	GTP/Mg2+ binding site [chemical binding]; other site
697329007294	Switch I region; other site
697329007295	G2 box; other site
697329007296	G3 box; other site
697329007297	Switch II region; other site
697329007298	G4 box; other site
697329007299	G5 box; other site
697329007300	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
697329007301	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cl00258
697329007302	active site
697329007303	metal binding site [ion binding]; metal-binding site
697329007304	dimerization interface [polypeptide binding]; other site
697329007305	hypothetical protein; Validated; Region: PRK00110
697329007306	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
697329007307	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
697329007308	substrate binding site [chemical binding]; other site
697329007309	ATP binding site [chemical binding]; other site
697329007310	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
697329007311	Double zinc ribbon; Region: DZR; pfam12773
697329007312	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
697329007313	Domain of unknown function DUF21; Region: DUF21; pfam01595
697329007314	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
697329007315	Transporter associated domain; Region: CorC_HlyC; smart01091
697329007316	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
697329007317	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329007318	Interdomain contacts; other site
697329007319	Cytokine receptor motif; other site
697329007320	Transglutaminase/protease-like homologues; Region: TGc; smart00460
697329007321	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
697329007322	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
697329007323	homodimer interface [polypeptide binding]; other site
697329007324	substrate-cofactor binding pocket; other site
697329007325	catalytic residue [active]
697329007326	Uncharacterized conserved protein [Function unknown]; Region: COG1624
697329007327	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
697329007328	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
697329007329	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
697329007330	HD domain; Region: HD_3; pfam13023
697329007331	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
697329007332	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
697329007333	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
697329007334	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329007335	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329007336	non-specific DNA binding site [nucleotide binding]; other site
697329007337	salt bridge; other site
697329007338	sequence-specific DNA binding site [nucleotide binding]; other site
697329007339	Domain of unknown function (DUF3784); Region: DUF3784; pfam12650
697329007340	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
697329007341	Bacterial SH3 domain; Region: SH3_3; cl17532
697329007342	Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193
697329007343	tRNA synthetases class I (M); Region: tRNA-synt_1g; pfam09334
697329007344	putative protein serine/threonine phosphatase; Provisional; Region: PRK14559
697329007345	mannosyl-3-phosphoglycerate phosphatase family; Region: HAD-SF-IIB-MPGP; TIGR01486
697329007346	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329007347	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
697329007348	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329007349	active site
697329007350	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
697329007351	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
697329007352	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
697329007353	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
697329007354	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329007355	motif II; other site
697329007356	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
697329007357	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
697329007358	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
697329007359	putative metal binding site [ion binding]; other site
697329007360	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
697329007361	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
697329007362	putative metal binding site [ion binding]; other site
697329007363	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
697329007364	Domain of unknown function (DUF4356); Region: DUF4356; pfam14266
697329007365	Domain of unknown function (DUF4356); Region: DUF4356; pfam14266
697329007366	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
697329007367	hypothetical protein; Provisional; Region: PRK05473
697329007368	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
697329007369	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
697329007370	putative tRNA-binding site [nucleotide binding]; other site
697329007371	B3/4 domain; Region: B3_4; pfam03483
697329007372	tRNA synthetase B5 domain; Region: B5; smart00874
697329007373	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
697329007374	dimer interface [polypeptide binding]; other site
697329007375	motif 1; other site
697329007376	motif 3; other site
697329007377	motif 2; other site
697329007378	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
697329007379	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
697329007380	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
697329007381	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
697329007382	dimer interface [polypeptide binding]; other site
697329007383	motif 1; other site
697329007384	active site
697329007385	motif 2; other site
697329007386	motif 3; other site
697329007387	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329007388	S-adenosylmethionine binding site [chemical binding]; other site
697329007389	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
697329007390	Domain of unknown function (DUF3783); Region: DUF3783; pfam12646
697329007391	oligoendopeptidase F; Region: pepF; TIGR00181
697329007392	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
697329007393	active site
697329007394	Zn binding site [ion binding]; other site
697329007395	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
697329007396	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
697329007397	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
697329007398	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
697329007399	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
697329007400	ATP-grasp domain; Region: ATP-grasp_4; cl17255
697329007401	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
697329007402	IMP binding site; other site
697329007403	dimer interface [polypeptide binding]; other site
697329007404	interdomain contacts; other site
697329007405	partial ornithine binding site; other site
697329007406	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
697329007407	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
697329007408	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
697329007409	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
697329007410	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
697329007411	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
697329007412	catalytic site [active]
697329007413	subunit interface [polypeptide binding]; other site
697329007414	Predicted membrane protein [Function unknown]; Region: COG4763
697329007415	PAS fold; Region: PAS_4; pfam08448
697329007416	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
697329007417	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
697329007418	substrate binding pocket [chemical binding]; other site
697329007419	membrane-bound complex binding site; other site
697329007420	hinge residues; other site
697329007421	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
697329007422	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
697329007423	substrate binding pocket [chemical binding]; other site
697329007424	membrane-bound complex binding site; other site
697329007425	hinge residues; other site
697329007426	PAS fold; Region: PAS_4; pfam08448
697329007427	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329007428	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329007429	metal binding site [ion binding]; metal-binding site
697329007430	active site
697329007431	I-site; other site
697329007432	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit [DNA replication, recombination, and repair]; Region: GyrB; COG0187
697329007433	DNA gyrase B; Region: DNA_gyraseB; pfam00204
697329007434	ATP binding site [chemical binding]; other site
697329007435	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
697329007436	active site
697329007437	metal binding site [ion binding]; metal-binding site
697329007438	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
697329007439	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
697329007440	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
697329007441	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
697329007442	CAP-like domain; other site
697329007443	active site
697329007444	primary dimer interface [polypeptide binding]; other site
697329007445	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
697329007446	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
697329007447	Walker A motif; other site
697329007448	ATP binding site [chemical binding]; other site
697329007449	Walker B motif; other site
697329007450	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
697329007451	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
697329007452	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
697329007453	Walker A motif; other site
697329007454	ATP binding site [chemical binding]; other site
697329007455	Walker B motif; other site
697329007456	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
697329007457	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
697329007458	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
697329007459	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
697329007460	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
697329007461	Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968
697329007462	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
697329007463	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
697329007464	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
697329007465	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
697329007466	V-type ATP synthase subunit I; Validated; Region: PRK05771
697329007467	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
697329007468	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
697329007469	generic binding surface II; other site
697329007470	ssDNA binding site; other site
697329007471	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329007472	ATP binding site [chemical binding]; other site
697329007473	putative Mg++ binding site [ion binding]; other site
697329007474	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329007475	nucleotide binding region [chemical binding]; other site
697329007476	ATP-binding site [chemical binding]; other site
697329007477	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
697329007478	N-terminal domain of chitobiose phosphorylase (ChBP) and similar proteins; Region: GH94N_ChBP_like; cd11755
697329007479	catalytic domain interface [polypeptide binding]; other site
697329007480	putative homodimer interface [polypeptide binding]; other site
697329007481	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
697329007482	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
697329007483	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
697329007484	Walker A/P-loop; other site
697329007485	ATP binding site [chemical binding]; other site
697329007486	Q-loop/lid; other site
697329007487	ABC transporter signature motif; other site
697329007488	Walker B; other site
697329007489	D-loop; other site
697329007490	H-loop/switch region; other site
697329007491	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
697329007492	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329007493	dimer interface [polypeptide binding]; other site
697329007494	conserved gate region; other site
697329007495	putative PBP binding loops; other site
697329007496	ABC-ATPase subunit interface; other site
697329007497	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
697329007498	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
697329007499	substrate binding pocket [chemical binding]; other site
697329007500	membrane-bound complex binding site; other site
697329007501	hinge residues; other site
697329007502	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
697329007503	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329007504	active site
697329007505	phosphorylation site [posttranslational modification]
697329007506	intermolecular recognition site; other site
697329007507	dimerization interface [polypeptide binding]; other site
697329007508	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
697329007509	dimerization interface [polypeptide binding]; other site
697329007510	DNA binding residues [nucleotide binding]
697329007511	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
697329007512	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
697329007513	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
697329007514	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
697329007515	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
697329007516	glutamate racemase; Provisional; Region: PRK00865
697329007517	Domain of unknown function (DUF1934); Region: DUF1934; cl01870
697329007518	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
697329007519	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
697329007520	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329007521	active site
697329007522	HIGH motif; other site
697329007523	nucleotide binding site [chemical binding]; other site
697329007524	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
697329007525	KMSK motif region; other site
697329007526	tRNA binding surface [nucleotide binding]; other site
697329007527	DALR anticodon binding domain; Region: DALR_1; smart00836
697329007528	anticodon binding site; other site
697329007529	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329007530	metal binding site [ion binding]; metal-binding site
697329007531	active site
697329007532	I-site; other site
697329007533	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329007534	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
697329007535	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329007536	active site
697329007537	metal binding site [ion binding]; metal-binding site
697329007538	homotetramer interface [polypeptide binding]; other site
697329007539	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
697329007540	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
697329007541	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
697329007542	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901
697329007543	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
697329007544	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
697329007545	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329007546	Zn2+ binding site [ion binding]; other site
697329007547	Mg2+ binding site [ion binding]; other site
697329007548	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
697329007549	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329007550	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329007551	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329007552	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
697329007553	DAK2 domain; Region: Dak2; pfam02734
697329007554	Asp23 family; Region: Asp23; pfam03780
697329007555	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
697329007556	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
697329007557	Walker A/P-loop; other site
697329007558	ATP binding site [chemical binding]; other site
697329007559	Q-loop/lid; other site
697329007560	ABC transporter signature motif; other site
697329007561	Walker B; other site
697329007562	D-loop; other site
697329007563	H-loop/switch region; other site
697329007564	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
697329007565	FeS assembly protein SufB; Region: sufB; TIGR01980
697329007566	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
697329007567	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
697329007568	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
697329007569	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
697329007570	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329007571	catalytic residue [active]
697329007572	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
697329007573	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
697329007574	trimerization site [polypeptide binding]; other site
697329007575	active site
697329007576	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
697329007577	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
697329007578	Glutamine amidotransferases class-II; Region: GATase_4; pfam13230
697329007579	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
697329007580	Transcriptional regulator; Region: Rrf2; cl17282
697329007581	Rrf2 family protein; Region: rrf2_super; TIGR00738
697329007582	Homoserine O-succinyltransferase; Region: HTS; pfam04204
697329007583	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
697329007584	proposed active site lysine [active]
697329007585	conserved cys residue [active]
697329007586	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cd00562
697329007587	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329007588	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
697329007589	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
697329007590	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
697329007591	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
697329007592	nitrogenase iron protein; Region: nifH; TIGR01287
697329007593	Nucleotide-binding sites [chemical binding]; other site
697329007594	Walker A motif; other site
697329007595	Switch I region of nucleotide binding site; other site
697329007596	Fe4S4 binding sites [ion binding]; other site
697329007597	Switch II region of nucleotide binding site; other site
697329007598	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329007599	Radical SAM superfamily; Region: Radical_SAM; pfam04055
697329007600	FeS/SAM binding site; other site
697329007601	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cd00562
697329007602	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
697329007603	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
697329007604	dimer interface [polypeptide binding]; other site
697329007605	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329007606	catalytic residue [active]
697329007607	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
697329007608	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
697329007609	homodimer interface [polypeptide binding]; other site
697329007610	substrate-cofactor binding pocket; other site
697329007611	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329007612	catalytic residue [active]
697329007613	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329007614	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
697329007615	DNA binding site [nucleotide binding]
697329007616	domain linker motif; other site
697329007617	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329007618	ligand binding site [chemical binding]; other site
697329007619	dimerization interface [polypeptide binding]; other site
697329007620	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329007621	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329007622	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
697329007623	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
697329007624	THF binding site; other site
697329007625	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
697329007626	substrate binding site [chemical binding]; other site
697329007627	THF binding site; other site
697329007628	zinc-binding site [ion binding]; other site
697329007629	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
697329007630	FAD binding site [chemical binding]; other site
697329007631	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329007632	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329007633	metal binding site [ion binding]; metal-binding site
697329007634	active site
697329007635	I-site; other site
697329007636	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
697329007637	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329007638	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
697329007639	Cellulose binding domain; Region: CBM_3; cl03026
697329007640	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329007641	Interdomain contacts; other site
697329007642	Cytokine receptor motif; other site
697329007643	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329007644	Interdomain contacts; other site
697329007645	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329007646	metal binding site [ion binding]; metal-binding site
697329007647	active site
697329007648	I-site; other site
697329007649	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
697329007650	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
697329007651	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
697329007652	active site
697329007653	catalytic tetrad [active]
697329007654	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
697329007655	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
697329007656	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
697329007657	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329007658	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329007659	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329007660	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329007661	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329007662	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
697329007663	dimerization interface [polypeptide binding]; other site
697329007664	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329007665	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329007666	Walker A/P-loop; other site
697329007667	ATP binding site [chemical binding]; other site
697329007668	Q-loop/lid; other site
697329007669	ABC transporter signature motif; other site
697329007670	Walker B; other site
697329007671	D-loop; other site
697329007672	H-loop/switch region; other site
697329007673	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329007674	FtsX-like permease family; Region: FtsX; pfam02687
697329007675	glutamate dehydrogenase; Provisional; Region: PRK09414
697329007676	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
697329007677	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
697329007678	NAD(P) binding site [chemical binding]; other site
697329007679	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
697329007680	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
697329007681	GIY-YIG motif/motif A; other site
697329007682	active site
697329007683	catalytic site [active]
697329007684	putative DNA binding site [nucleotide binding]; other site
697329007685	metal binding site [ion binding]; metal-binding site
697329007686	UvrB/uvrC motif; Region: UVR; pfam02151
697329007687	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
697329007688	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
697329007689	active site
697329007690	catalytic residues [active]
697329007691	metal binding site [ion binding]; metal-binding site
697329007692	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
697329007693	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
697329007694	active site
697329007695	metal binding site [ion binding]; metal-binding site
697329007696	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
697329007697	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
697329007698	dimerization interface [polypeptide binding]; other site
697329007699	domain crossover interface; other site
697329007700	redox-dependent activation switch; other site
697329007701	Methyltransferase domain; Region: Methyltransf_31; pfam13847
697329007702	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329007703	S-adenosylmethionine binding site [chemical binding]; other site
697329007704	Trp repressor protein; Region: Trp_repressor; cl17266
697329007705	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329007706	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
697329007707	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
697329007708	active site
697329007709	Int/Topo IB signature motif; other site
697329007710	catalytic residues [active]
697329007711	DNA binding site [nucleotide binding]
697329007712	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
697329007713	non-specific DNA binding site [nucleotide binding]; other site
697329007714	salt bridge; other site
697329007715	sequence-specific DNA binding site [nucleotide binding]; other site
697329007716	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329007717	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
697329007718	catalytic residues [active]
697329007719	catalytic nucleophile [active]
697329007720	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
697329007721	G1 box; other site
697329007722	GTP/Mg2+ binding site [chemical binding]; other site
697329007723	Switch I region; other site
697329007724	G2 box; other site
697329007725	G3 box; other site
697329007726	Switch II region; other site
697329007727	G4 box; other site
697329007728	G5 box; other site
697329007729	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
697329007730	active site
697329007731	catalytic motif [active]
697329007732	Zn binding site [ion binding]; other site
697329007733	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
697329007734	Found in ATP-dependent protease La (LON); Region: LON; smart00464
697329007735	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329007736	Walker A motif; other site
697329007737	ATP binding site [chemical binding]; other site
697329007738	Walker B motif; other site
697329007739	arginine finger; other site
697329007740	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
697329007741	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
697329007742	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
697329007743	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
697329007744	dimer interface [polypeptide binding]; other site
697329007745	ssDNA binding site [nucleotide binding]; other site
697329007746	tetramer (dimer of dimers) interface [polypeptide binding]; other site
697329007747	Ribosomal protein S6; Region: Ribosomal_S6; pfam01250
697329007748	Prokaryotic RING finger family 1; Region: Prok-RING_1; pfam14446
697329007749	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329007750	Double zinc ribbon; Region: DZR; pfam12773
697329007751	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
697329007752	Transcriptional regulator [Transcription]; Region: LytR; COG1316
697329007753	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
697329007754	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
697329007755	active site
697329007756	Catalytic domain of Protein Kinases; Region: PKc; cd00180
697329007757	active site
697329007758	ATP binding site [chemical binding]; other site
697329007759	substrate binding site [chemical binding]; other site
697329007760	activation loop (A-loop); other site
697329007761	PASTA domain; Region: PASTA; pfam03793
697329007762	PASTA domain; Region: PASTA; pfam03793
697329007763	6-phosphofructokinase; Provisional; Region: PRK03202
697329007764	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
697329007765	active site
697329007766	ADP/pyrophosphate binding site [chemical binding]; other site
697329007767	dimerization interface [polypeptide binding]; other site
697329007768	allosteric effector site; other site
697329007769	fructose-1,6-bisphosphate binding site; other site
697329007770	peptide chain release factor 2; Validated; Region: prfB; PRK00578
697329007771	This domain is found in peptide chain release factors; Region: PCRF; smart00937
697329007772	RF-1 domain; Region: RF-1; pfam00472
697329007773	Protein of unknown function, DUF624; Region: DUF624; cl02369
697329007774	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
697329007775	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
697329007776	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329007777	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329007778	dimer interface [polypeptide binding]; other site
697329007779	phosphorylation site [posttranslational modification]
697329007780	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329007781	ATP binding site [chemical binding]; other site
697329007782	Mg2+ binding site [ion binding]; other site
697329007783	G-X-G motif; other site
697329007784	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
697329007785	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329007786	active site
697329007787	phosphorylation site [posttranslational modification]
697329007788	intermolecular recognition site; other site
697329007789	dimerization interface [polypeptide binding]; other site
697329007790	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
697329007791	23S rRNA interface [nucleotide binding]; other site
697329007792	L3 interface [polypeptide binding]; other site
697329007793	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
697329007794	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
697329007795	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
697329007796	active site
697329007797	catalytic residues [active]
697329007798	DNA binding site [nucleotide binding]
697329007799	Int/Topo IB signature motif; other site
697329007800	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329007801	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329007802	non-specific DNA binding site [nucleotide binding]; other site
697329007803	salt bridge; other site
697329007804	sequence-specific DNA binding site [nucleotide binding]; other site
697329007805	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
697329007806	Protein of unknown function DUF262; Region: DUF262; pfam03235
697329007807	Uncharacterized conserved protein [Function unknown]; Region: COG1479
697329007808	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
697329007809	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
697329007810	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329007811	Int/Topo IB signature motif; other site
697329007812	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
697329007813	CHC2 zinc finger; Region: zf-CHC2; cl17510
697329007814	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329007815	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
697329007816	Protein of unknown function (Hypoth_ymh); Region: Hypoth_Ymh; pfam09509
697329007817	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329007818	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329007819	Eco47II restriction endonuclease; Region: RE_Eco47II; pfam09553
697329007820	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
697329007821	non-specific DNA binding site [nucleotide binding]; other site
697329007822	salt bridge; other site
697329007823	sequence-specific DNA binding site [nucleotide binding]; other site
697329007824	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
697329007825	cofactor binding site; other site
697329007826	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
697329007827	DNA binding site [nucleotide binding]
697329007828	substrate interaction site [chemical binding]; other site
697329007829	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329007830	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329007831	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329007832	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329007833	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329007834	active site
697329007835	DNA binding site [nucleotide binding]
697329007836	Int/Topo IB signature motif; other site
697329007837	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
697329007838	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329007839	active site
697329007840	DNA binding site [nucleotide binding]
697329007841	Int/Topo IB signature motif; other site
697329007842	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329007843	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329007844	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329007845	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329007846	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329007847	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
697329007848	oligomerization interface [polypeptide binding]; other site
697329007849	active site
697329007850	metal binding site [ion binding]; metal-binding site
697329007851	Pantoate-beta-alanine ligase; Region: PanC; cd00560
697329007852	pantoate--beta-alanine ligase; Region: panC; TIGR00018
697329007853	active site
697329007854	ATP-binding site [chemical binding]; other site
697329007855	pantoate-binding site; other site
697329007856	HXXH motif; other site
697329007857	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
697329007858	tetramerization interface [polypeptide binding]; other site
697329007859	active site
697329007860	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329007861	Interdomain contacts; other site
697329007862	Cytokine receptor motif; other site
697329007863	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329007864	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329007865	Rhamnogalacturonan lyase of the polysaccharide lyase family 11; Region: RGL11; cd10318
697329007866	metal binding site [ion binding]; metal-binding site
697329007867	active site
697329007868	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
697329007869	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
697329007870	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329007871	putative sugar binding sites [chemical binding]; other site
697329007872	Q-X-W motif; other site
697329007873	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329007874	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
697329007875	putative sugar binding sites [chemical binding]; other site
697329007876	Q-X-W motif; other site
697329007877	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
697329007878	active site
697329007879	catalytic triad [active]
697329007880	oxyanion hole [active]
697329007881	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
697329007882	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
697329007883	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329007884	putative sugar binding sites [chemical binding]; other site
697329007885	Q-X-W motif; other site
697329007886	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329007887	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
697329007888	putative sugar binding sites [chemical binding]; other site
697329007889	Q-X-W motif; other site
697329007890	serine O-acetyltransferase; Region: cysE; TIGR01172
697329007891	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
697329007892	trimer interface [polypeptide binding]; other site
697329007893	active site
697329007894	substrate binding site [chemical binding]; other site
697329007895	CoA binding site [chemical binding]; other site
697329007896	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329007897	Interdomain contacts; other site
697329007898	GAD-like domain; Region: GAD-like; pfam08887
697329007899	Domain of unknown function (DUF1851); Region: DUF1851; pfam08906
697329007900	spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869
697329007901	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
697329007902	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
697329007903	GTP-binding protein YchF; Reviewed; Region: PRK09601
697329007904	YchF GTPase; Region: YchF; cd01900
697329007905	G1 box; other site
697329007906	GTP/Mg2+ binding site [chemical binding]; other site
697329007907	Switch I region; other site
697329007908	G2 box; other site
697329007909	Switch II region; other site
697329007910	G3 box; other site
697329007911	G4 box; other site
697329007912	G5 box; other site
697329007913	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
697329007914	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329007915	FtsX-like permease family; Region: FtsX; pfam02687
697329007916	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
697329007917	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329007918	FtsX-like permease family; Region: FtsX; pfam02687
697329007919	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
697329007920	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
697329007921	HD domain; Region: HD_4; pfam13328
697329007922	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
697329007923	nudix motif; other site
697329007924	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
697329007925	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
697329007926	active site
697329007927	substrate binding site [chemical binding]; other site
697329007928	metal binding site [ion binding]; metal-binding site
697329007929	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329007930	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329007931	Coenzyme A binding pocket [chemical binding]; other site
697329007932	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329007933	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
697329007934	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329007935	Walker A motif; other site
697329007936	ATP binding site [chemical binding]; other site
697329007937	Walker B motif; other site
697329007938	arginine finger; other site
697329007939	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
697329007940	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
697329007941	RuvA N terminal domain; Region: RuvA_N; pfam01330
697329007942	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
697329007943	active site
697329007944	putative DNA-binding cleft [nucleotide binding]; other site
697329007945	dimer interface [polypeptide binding]; other site
697329007946	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
697329007947	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
697329007948	hinge; other site
697329007949	active site
697329007950	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
697329007951	Rubredoxin; Region: Rubredoxin; pfam00301
697329007952	iron binding site [ion binding]; other site
697329007953	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329007954	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
697329007955	active site
697329007956	motif I; other site
697329007957	motif II; other site
697329007958	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329007959	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
697329007960	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
697329007961	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329007962	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329007963	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
697329007964	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
697329007965	mRNA/rRNA interface [nucleotide binding]; other site
697329007966	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
697329007967	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
697329007968	23S rRNA interface [nucleotide binding]; other site
697329007969	L7/L12 interface [polypeptide binding]; other site
697329007970	putative thiostrepton binding site; other site
697329007971	L25 interface [polypeptide binding]; other site
697329007972	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
697329007973	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
697329007974	putative homodimer interface [polypeptide binding]; other site
697329007975	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
697329007976	heterodimer interface [polypeptide binding]; other site
697329007977	homodimer interface [polypeptide binding]; other site
697329007978	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
697329007979	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
697329007980	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
697329007981	oxyanion hole [active]
697329007982	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
697329007983	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
697329007984	protein binding site [polypeptide binding]; other site
697329007985	Transcriptional regulator [Transcription]; Region: LytR; COG1316
697329007986	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
697329007987	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329007988	NAD(P) binding site [chemical binding]; other site
697329007989	active site
697329007990	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
697329007991	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329007992	active site
697329007993	metal binding site [ion binding]; metal-binding site
697329007994	DNA binding site [nucleotide binding]
697329007995	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
697329007996	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
697329007997	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329007998	Walker A/P-loop; other site
697329007999	ATP binding site [chemical binding]; other site
697329008000	Q-loop/lid; other site
697329008001	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
697329008002	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329008003	Walker B; other site
697329008004	D-loop; other site
697329008005	H-loop/switch region; other site
697329008006	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
697329008007	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
697329008008	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
697329008009	active site
697329008010	dimer interface [polypeptide binding]; other site
697329008011	ATP-grasp domain; Region: ATP-grasp_4; cl17255
697329008012	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
697329008013	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
697329008014	G1 box; other site
697329008015	putative GEF interaction site [polypeptide binding]; other site
697329008016	GTP/Mg2+ binding site [chemical binding]; other site
697329008017	Switch I region; other site
697329008018	G2 box; other site
697329008019	G3 box; other site
697329008020	Switch II region; other site
697329008021	G4 box; other site
697329008022	G5 box; other site
697329008023	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
697329008024	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
697329008025	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
697329008026	homodimer interface [polypeptide binding]; other site
697329008027	substrate-cofactor binding pocket; other site
697329008028	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329008029	catalytic residue [active]
697329008030	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
697329008031	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
697329008032	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329008033	S-adenosylmethionine binding site [chemical binding]; other site
697329008034	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
697329008035	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
697329008036	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329008037	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329008038	metal binding site [ion binding]; metal-binding site
697329008039	active site
697329008040	I-site; other site
697329008041	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329008042	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329008043	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
697329008044	DNA binding site [nucleotide binding]
697329008045	domain linker motif; other site
697329008046	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
697329008047	Pectate lyase [Carbohydrate transport and metabolism]; Region: PelB; COG3866
697329008048	Pectate lyase; Region: Pec_lyase_C; cl01593
697329008049	Pectate lyase; Region: Pec_lyase_C; cl01593
697329008050	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
697329008051	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
697329008052	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
697329008053	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
697329008054	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329008055	Walker A/P-loop; other site
697329008056	ATP binding site [chemical binding]; other site
697329008057	Q-loop/lid; other site
697329008058	ABC transporter signature motif; other site
697329008059	Walker B; other site
697329008060	D-loop; other site
697329008061	H-loop/switch region; other site
697329008062	Glycosyl hydrolase family 48; Region: Glyco_hydro_48; pfam02011
697329008063	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329008064	Interdomain contacts; other site
697329008065	QueT transporter; Region: QueT; pfam06177
697329008066	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
697329008067	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
697329008068	intersubunit interface [polypeptide binding]; other site
697329008069	active site
697329008070	zinc binding site [ion binding]; other site
697329008071	Na+ binding site [ion binding]; other site
697329008072	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329008073	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329008074	Response regulator receiver domain; Region: Response_reg; pfam00072
697329008075	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329008076	active site
697329008077	phosphorylation site [posttranslational modification]
697329008078	intermolecular recognition site; other site
697329008079	dimerization interface [polypeptide binding]; other site
697329008080	ANTAR domain; Region: ANTAR; pfam03861
697329008081	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
697329008082	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
697329008083	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
697329008084	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
697329008085	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
697329008086	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
697329008087	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
697329008088	RNA binding site [nucleotide binding]; other site
697329008089	Alpha-glucuronidase [Carbohydrate transport and metabolism]; Region: AguA; COG3661
697329008090	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
697329008091	Glycosyl hydrolase family 67 C-terminus; Region: Glyco_hydro_67C; pfam07477
697329008092	Domain of unknown function (DUF303); Region: DUF303; pfam03629
697329008093	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
697329008094	Domain of unknown function (DUF303); Region: DUF303; pfam03629
697329008095	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329008096	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
697329008097	ligand binding site [chemical binding]; other site
697329008098	dimerization interface [polypeptide binding]; other site
697329008099	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
697329008100	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329008101	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329008102	metal binding site [ion binding]; metal-binding site
697329008103	active site
697329008104	I-site; other site
697329008105	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
697329008106	active site
697329008107	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
697329008108	RNA methyltransferase, RsmE family; Region: TIGR00046
697329008109	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
697329008110	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
697329008111	Bacterial PH domain; Region: DUF304; pfam03703
697329008112	Isochorismatase family; Region: Isochorismatase; pfam00857
697329008113	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
697329008114	catalytic triad [active]
697329008115	conserved cis-peptide bond; other site
697329008116	Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; Region: PrsA; COG0462
697329008117	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
697329008118	active site
697329008119	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
697329008120	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
697329008121	active site
697329008122	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
697329008123	PLD-like domain; Region: PLDc_2; pfam13091
697329008124	putative active site [active]
697329008125	catalytic site [active]
697329008126	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
697329008127	PLD-like domain; Region: PLDc_2; pfam13091
697329008128	putative active site [active]
697329008129	catalytic site [active]
697329008130	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329008131	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329008132	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329008133	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
697329008134	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329008135	lichenase, member of glycosyl hydrolase family 16; Region: GH16_lichenase; cd02175
697329008136	Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]; Region: SKN1; COG2273
697329008137	active site
697329008138	active site
697329008139	catalytic residues [active]
697329008140	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
697329008141	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
697329008142	putative sugar binding sites [chemical binding]; other site
697329008143	Q-X-W motif; other site
697329008144	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
697329008145	Dockerin type I repeat; Region: Dockerin_1; pfam00404
697329008146	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
697329008147	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
697329008148	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
697329008149	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
697329008150	putative dimer interface [polypeptide binding]; other site
697329008151	putative anticodon binding site; other site
697329008152	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
697329008153	homodimer interface [polypeptide binding]; other site
697329008154	motif 1; other site
697329008155	motif 2; other site
697329008156	active site
697329008157	motif 3; other site
697329008158	asparagine synthetase AsnA; Provisional; Region: PRK05425
697329008159	motif 1; other site
697329008160	dimer interface [polypeptide binding]; other site
697329008161	active site
697329008162	motif 2; other site
697329008163	motif 3; other site
697329008164	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329008165	FtsX-like permease family; Region: FtsX; pfam02687
697329008166	FtsX-like permease family; Region: FtsX; pfam02687
697329008167	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329008168	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329008169	Walker A/P-loop; other site
697329008170	ATP binding site [chemical binding]; other site
697329008171	Q-loop/lid; other site
697329008172	ABC transporter signature motif; other site
697329008173	Walker B; other site
697329008174	D-loop; other site
697329008175	H-loop/switch region; other site
697329008176	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329008177	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329008178	active site
697329008179	phosphorylation site [posttranslational modification]
697329008180	intermolecular recognition site; other site
697329008181	dimerization interface [polypeptide binding]; other site
697329008182	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329008183	DNA binding site [nucleotide binding]
697329008184	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329008185	HAMP domain; Region: HAMP; pfam00672
697329008186	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329008187	phosphorylation site [posttranslational modification]
697329008188	dimer interface [polypeptide binding]; other site
697329008189	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329008190	ATP binding site [chemical binding]; other site
697329008191	Mg2+ binding site [ion binding]; other site
697329008192	G-X-G motif; other site
697329008193	GAD-like domain; Region: GAD-like; pfam08887
697329008194	Domain of unknown function (DUF1851); Region: DUF1851; pfam08906
697329008195	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
697329008196	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
697329008197	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329008198	dimer interface [polypeptide binding]; other site
697329008199	conserved gate region; other site
697329008200	ABC-ATPase subunit interface; other site
697329008201	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
697329008202	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329008203	dimer interface [polypeptide binding]; other site
697329008204	conserved gate region; other site
697329008205	putative PBP binding loops; other site
697329008206	ABC-ATPase subunit interface; other site
697329008207	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329008208	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329008209	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
697329008210	active site
697329008211	metal binding site [ion binding]; metal-binding site
697329008212	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
697329008213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
697329008214	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
697329008215	putative ADP-ribose binding site [chemical binding]; other site
697329008216	putative active site [active]
697329008217	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
697329008218	AAA domain; Region: AAA_30; pfam13604
697329008219	Family description; Region: UvrD_C_2; pfam13538
697329008220	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
697329008221	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
697329008222	RNase E interface [polypeptide binding]; other site
697329008223	trimer interface [polypeptide binding]; other site
697329008224	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
697329008225	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
697329008226	RNase E interface [polypeptide binding]; other site
697329008227	trimer interface [polypeptide binding]; other site
697329008228	active site
697329008229	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
697329008230	putative nucleic acid binding region [nucleotide binding]; other site
697329008231	G-X-X-G motif; other site
697329008232	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
697329008233	RNA binding site [nucleotide binding]; other site
697329008234	domain interface; other site
697329008235	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
697329008236	16S/18S rRNA binding site [nucleotide binding]; other site
697329008237	S13e-L30e interaction site [polypeptide binding]; other site
697329008238	25S rRNA binding site [nucleotide binding]; other site
697329008239	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
697329008240	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
697329008241	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
697329008242	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
697329008243	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
697329008244	Clp amino terminal domain; Region: Clp_N; pfam02861
697329008245	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329008246	Walker A motif; other site
697329008247	ATP binding site [chemical binding]; other site
697329008248	Walker B motif; other site
697329008249	arginine finger; other site
697329008250	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329008251	Walker A motif; other site
697329008252	ATP binding site [chemical binding]; other site
697329008253	Walker B motif; other site
697329008254	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
697329008255	Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; pfam09547
697329008256	stage IV sporulation protein A; Region: spore_IV_A; TIGR02836
697329008257	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
697329008258	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
697329008259	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
697329008260	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
697329008261	homodimer interface [polypeptide binding]; other site
697329008262	substrate-cofactor binding pocket; other site
697329008263	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329008264	catalytic residue [active]
697329008265	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329008266	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329008267	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
697329008268	dimerization interface [polypeptide binding]; other site
697329008269	heat shock protein 90; Provisional; Region: PRK05218
697329008270	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329008271	ATP binding site [chemical binding]; other site
697329008272	Mg2+ binding site [ion binding]; other site
697329008273	G-X-G motif; other site
697329008274	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
697329008275	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
697329008276	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
697329008277	Cache domain; Region: Cache_1; pfam02743
697329008278	Cache domain; Region: Cache_1; pfam02743
697329008279	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329008280	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329008281	dimer interface [polypeptide binding]; other site
697329008282	phosphorylation site [posttranslational modification]
697329008283	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329008284	ATP binding site [chemical binding]; other site
697329008285	Mg2+ binding site [ion binding]; other site
697329008286	G-X-G motif; other site
697329008287	Response regulator receiver domain; Region: Response_reg; pfam00072
697329008288	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329008289	active site
697329008290	phosphorylation site [posttranslational modification]
697329008291	intermolecular recognition site; other site
697329008292	dimerization interface [polypeptide binding]; other site
697329008293	PemK-like protein; Region: PemK; pfam02452
697329008294	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
697329008295	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329008296	Int/Topo IB signature motif; other site
697329008297	Helix-turn-helix domain; Region: HTH_17; cl17695
697329008298	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
697329008299	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329008300	Double zinc ribbon; Region: DZR; pfam12773
697329008301	Catalytic domain of Protein Kinases; Region: PKc; cd00180
697329008302	active site
697329008303	ATP binding site [chemical binding]; other site
697329008304	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
697329008305	substrate binding site [chemical binding]; other site
697329008306	activation loop (A-loop); other site
697329008307	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329008308	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329008309	non-specific DNA binding site [nucleotide binding]; other site
697329008310	salt bridge; other site
697329008311	sequence-specific DNA binding site [nucleotide binding]; other site
697329008312	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329008313	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329008314	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329008315	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
697329008316	Transposase; Region: DEDD_Tnp_IS110; pfam01548
697329008317	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
697329008318	AAA domain; Region: AAA_25; pfam13481
697329008319	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
697329008320	Walker A motif; other site
697329008321	ATP binding site [chemical binding]; other site
697329008322	Walker B motif; other site
697329008323	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
697329008324	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329008325	Int/Topo IB signature motif; other site
697329008326	Helix-turn-helix domain; Region: HTH_17; pfam12728
697329008327	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
697329008328	Transposase; Region: DEDD_Tnp_IS110; pfam01548
697329008329	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
697329008330	AAA domain; Region: AAA_25; pfam13481
697329008331	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
697329008332	Walker A motif; other site
697329008333	ATP binding site [chemical binding]; other site
697329008334	Walker B motif; other site
697329008335	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329008336	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008337	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329008338	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008339	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008340	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008341	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008342	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
697329008343	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008344	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008345	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008346	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008347	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
697329008348	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329008349	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329008350	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329008351	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329008352	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329008353	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329008354	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329008355	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329008356	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329008357	non-specific DNA binding site [nucleotide binding]; other site
697329008358	salt bridge; other site
697329008359	sequence-specific DNA binding site [nucleotide binding]; other site
697329008360	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329008361	Int/Topo IB signature motif; other site
697329008362	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329008363	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329008364	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329008365	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329008366	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329008367	non-specific DNA binding site [nucleotide binding]; other site
697329008368	salt bridge; other site
697329008369	sequence-specific DNA binding site [nucleotide binding]; other site
697329008370	Helix-turn-helix domain; Region: HTH_17; cl17695
697329008371	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
697329008372	Arc-like DNA binding domain; Region: Arc; pfam03869
697329008373	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
697329008374	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
697329008375	Xanthomonas XOO_2897-like deaminase; Region: XOO_2897-deam; pfam14440
697329008376	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
697329008377	Isochorismatase family; Region: Isochorismatase; pfam00857
697329008378	catalytic triad [active]
697329008379	conserved cis-peptide bond; other site
697329008380	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
697329008381	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
697329008382	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
697329008383	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
697329008384	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
697329008385	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329008386	AMP-binding enzyme; Region: AMP-binding; pfam00501
697329008387	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329008388	acyl-activating enzyme (AAE) consensus motif; other site
697329008389	acyl-activating enzyme (AAE) consensus motif; other site
697329008390	active site
697329008391	AMP binding site [chemical binding]; other site
697329008392	CoA binding site [chemical binding]; other site
697329008393	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329008394	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329008395	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
697329008396	Interdomain contacts; other site
697329008397	Cytokine receptor motif; other site
697329008398	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329008399	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329008400	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
697329008401	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
697329008402	Peptidase family M23; Region: Peptidase_M23; pfam01551
697329008403	Septum formation initiator; Region: DivIC; cl17659
697329008404	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
697329008405	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
697329008406	Peptidase family M23; Region: Peptidase_M23; pfam01551
697329008407	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
697329008408	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
697329008409	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
697329008410	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
697329008411	Walker A/P-loop; other site
697329008412	ATP binding site [chemical binding]; other site
697329008413	Q-loop/lid; other site
697329008414	ABC transporter signature motif; other site
697329008415	Walker B; other site
697329008416	D-loop; other site
697329008417	H-loop/switch region; other site
697329008418	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
697329008419	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
697329008420	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
697329008421	dimerization domain swap beta strand [polypeptide binding]; other site
697329008422	regulatory protein interface [polypeptide binding]; other site
697329008423	active site
697329008424	regulatory phosphorylation site [posttranslational modification]; other site
697329008425	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
697329008426	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
697329008427	RimM N-terminal domain; Region: RimM; pfam01782
697329008428	PRC-barrel domain; Region: PRC; pfam05239
697329008429	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
697329008430	Catalytic NodB homology domain of Clostridium thermocellum acetylxylan esterase and its bacterial homologs; Region: CE4_CtAXE_like; cd10954
697329008431	NodB motif; other site
697329008432	active site
697329008433	catalytic site [active]
697329008434	Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Region: Endoglucanase_E_like; cd01831
697329008435	active site
697329008436	catalytic triad [active]
697329008437	oxyanion hole [active]
697329008438	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329008439	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
697329008440	acyl-activating enzyme (AAE) consensus motif; other site
697329008441	AMP binding site [chemical binding]; other site
697329008442	active site
697329008443	CoA binding site [chemical binding]; other site
697329008444	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
697329008445	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
697329008446	Walker A motif; other site
697329008447	ATP binding site [chemical binding]; other site
697329008448	DNA polymerase III subunit delta'; Validated; Region: PRK08485
697329008449	Protein of unknown function (DUF970); Region: DUF970; cl17525
697329008450	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
697329008451	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
697329008452	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
697329008453	catalytic residue [active]
697329008454	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329008455	DNA binding residues [nucleotide binding]
697329008456	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
697329008457	Predicted transcriptional regulator [Transcription]; Region: COG2378
697329008458	WYL domain; Region: WYL; pfam13280
697329008459	purine nucleoside phosphorylase; Provisional; Region: PRK08202
697329008460	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
697329008461	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
697329008462	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
697329008463	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329008464	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329008465	metal binding site [ion binding]; metal-binding site
697329008466	active site
697329008467	I-site; other site
697329008468	CBD_II domain; Region: CBD_II; smart00637
697329008469	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
697329008470	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
697329008471	active site
697329008472	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
697329008473	putative deacylase active site [active]
697329008474	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329008475	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
697329008476	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
697329008477	CBD_II domain; Region: CBD_II; smart00637
697329008478	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
697329008479	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
697329008480	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
697329008481	FAD binding site [chemical binding]; other site
697329008482	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
697329008483	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
697329008484	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
697329008485	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
697329008486	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
697329008487	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329008488	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
697329008489	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
697329008490	Protein of unknown function (DUF4241); Region: DUF4241; pfam14025
697329008491	Protein of unknown function (DUF4241); Region: DUF4241; pfam14025
697329008492	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329008493	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
697329008494	active site
697329008495	motif I; other site
697329008496	motif II; other site
697329008497	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
697329008498	motif II; other site
697329008499	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
697329008500	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
697329008501	Sulfatase; Region: Sulfatase; cl17466
697329008502	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
697329008503	Peptidase family M50; Region: Peptidase_M50; pfam02163
697329008504	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
697329008505	active site
697329008506	putative substrate binding region [chemical binding]; other site
697329008507	ScpA/B protein; Region: ScpA_ScpB; cl00598
697329008508	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
697329008509	Sporulation protein YtfJ (Spore_YtfJ); Region: Spore_YtfJ; cl01596
697329008510	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
697329008511	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
697329008512	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
697329008513	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
697329008514	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
697329008515	RNA binding surface [nucleotide binding]; other site
697329008516	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
697329008517	active site
697329008518	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
697329008519	active site
697329008520	catalytic triad [active]
697329008521	oxyanion hole [active]
697329008522	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
697329008523	putative transporter; Provisional; Region: PRK11660
697329008524	Sulfate transporter family; Region: Sulfate_transp; pfam00916
697329008525	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
697329008526	Predicted permeases [General function prediction only]; Region: COG0679
697329008527	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
697329008528	active site 2 [active]
697329008529	active site 1 [active]
697329008530	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
697329008531	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
697329008532	active site 2 [active]
697329008533	exopolysaccharide/PEP-CTERM locus tyrosine autokinase; Region: pepcterm_TyrKin; TIGR03018
697329008534	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
697329008535	Chain length determinant protein; Region: Wzz; cl15801
697329008536	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
697329008537	Bacterial SH3 domain; Region: SH3_3; pfam08239
697329008538	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
697329008539	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
697329008540	active site
697329008541	Phosphopantetheinyl transferase (holo-ACP synthase) [Lipid metabolism]; Region: AcpS; COG0736
697329008542	putative carbohydrate kinase; Provisional; Region: PRK10565
697329008543	Uncharacterized conserved protein [Function unknown]; Region: COG0062
697329008544	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
697329008545	putative substrate binding site [chemical binding]; other site
697329008546	putative ATP binding site [chemical binding]; other site
697329008547	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
697329008548	Response regulator receiver domain; Region: Response_reg; pfam00072
697329008549	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329008550	active site
697329008551	phosphorylation site [posttranslational modification]
697329008552	intermolecular recognition site; other site
697329008553	dimerization interface [polypeptide binding]; other site
697329008554	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329008555	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329008556	non-specific DNA binding site [nucleotide binding]; other site
697329008557	salt bridge; other site
697329008558	sequence-specific DNA binding site [nucleotide binding]; other site
697329008559	Superoxide reductase-like (SORL) domain; present in a family of mononuclear non-heme iron proteins that includes superoxide reductase and desulfoferrodoxin. Superoxide reductase-like proteins scavenge superoxide anion radicals as a defense mechanism...; Region: SORL; cl00014
697329008560	non-heme iron binding site [ion binding]; other site
697329008561	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
697329008562	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
697329008563	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
697329008564	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
697329008565	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
697329008566	Domain of unknown function (DUF814); Region: DUF814; pfam05670
697329008567	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
697329008568	nudix motif; other site
697329008569	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
697329008570	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
697329008571	Ligand binding site; other site
697329008572	Putative Catalytic site; other site
697329008573	DXD motif; other site
697329008574	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
697329008575	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
697329008576	active site
697329008577	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329008578	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329008579	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
697329008580	NPCBM/NEW2 domain; Region: NPCBM; cl07060
697329008581	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329008582	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329008583	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329008584	DNA binding residues [nucleotide binding]
697329008585	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
697329008586	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
697329008587	intersubunit interface [polypeptide binding]; other site
697329008588	active site
697329008589	Zn2+ binding site [ion binding]; other site
697329008590	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
697329008591	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329008592	Coenzyme A binding pocket [chemical binding]; other site
697329008593	Protein of unknown function (DUF419); Region: DUF419; cl15265
697329008594	L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-RBK_like; cd07778
697329008595	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
697329008596	putative N- and C-terminal domain interface [polypeptide binding]; other site
697329008597	putative active site [active]
697329008598	MgATP binding site [chemical binding]; other site
697329008599	catalytic site [active]
697329008600	metal binding site [ion binding]; metal-binding site
697329008601	putative carbohydrate binding site [chemical binding]; other site
697329008602	FtsX-like permease family; Region: FtsX; pfam02687
697329008603	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
697329008604	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
697329008605	FtsX-like permease family; Region: FtsX; pfam02687
697329008606	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329008607	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329008608	Walker A/P-loop; other site
697329008609	ATP binding site [chemical binding]; other site
697329008610	Q-loop/lid; other site
697329008611	ABC transporter signature motif; other site
697329008612	Walker B; other site
697329008613	D-loop; other site
697329008614	H-loop/switch region; other site
697329008615	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
697329008616	Walker A motif; other site
697329008617	ATP binding site [chemical binding]; other site
697329008618	Walker B motif; other site
697329008619	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
697329008620	metal ion-dependent adhesion site (MIDAS); other site
697329008621	enolase; Provisional; Region: eno; PRK00077
697329008622	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
697329008623	dimer interface [polypeptide binding]; other site
697329008624	metal binding site [ion binding]; metal-binding site
697329008625	substrate binding pocket [chemical binding]; other site
697329008626	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329008627	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329008628	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
697329008629	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329008630	DNA binding residues [nucleotide binding]
697329008631	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
697329008632	substrate binding site [chemical binding]; other site
697329008633	active site
697329008634	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
697329008635	ligand binding site [chemical binding]; other site
697329008636	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
697329008637	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329008638	motif II; other site
697329008639	AAA domain; Region: AAA_17; pfam13207
697329008640	AAA domain; Region: AAA_33; pfam13671
697329008641	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
697329008642	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329008643	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
697329008644	protein-splicing catalytic site; other site
697329008645	thioester formation/cholesterol transfer; other site
697329008646	Pretoxin HINT domain; Region: PT-HINT; pfam07591
697329008647	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cd00688
697329008648	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
697329008649	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
697329008650	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
697329008651	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329008652	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
697329008653	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
697329008654	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
697329008655	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
697329008656	Transposon-encoded protein TnpW; Region: TnpW; pfam14202
697329008657	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329008658	Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a...; Region: SR_TndX_transposase; cd03770
697329008659	putative catalytic residues [active]
697329008660	catalytic nucleophile [active]
697329008661	Recombinase; Region: Recombinase; pfam07508
697329008662	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329008663	Domain of unknown function (DUF4368); Region: DUF4368; pfam14287
697329008664	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
697329008665	N- and C-terminal domain interface [polypeptide binding]; other site
697329008666	D-xylulose kinase; Region: XylB; TIGR01312
697329008667	active site
697329008668	MgATP binding site [chemical binding]; other site
697329008669	catalytic site [active]
697329008670	metal binding site [ion binding]; metal-binding site
697329008671	xylulose binding site [chemical binding]; other site
697329008672	homodimer interface [polypeptide binding]; other site
697329008673	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
697329008674	Domain of unknown function (DUF4177); Region: DUF4177; pfam13783
697329008675	Flavin reductase like domain; Region: Flavin_Reduct; pfam01613
697329008676	Rubredoxin [Energy production and conversion]; Region: COG1773
697329008677	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
697329008678	iron binding site [ion binding]; other site
697329008679	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
697329008680	Rubredoxin; Region: Rubredoxin; pfam00301
697329008681	iron binding site [ion binding]; other site
697329008682	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
697329008683	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
697329008684	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
697329008685	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
697329008686	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
697329008687	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
697329008688	nucleotide binding site [chemical binding]; other site
697329008689	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
697329008690	dihydroorotase; Validated; Region: pyrC; PRK09357
697329008691	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
697329008692	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
697329008693	active site
697329008694	Pleckstrin homology-like domain; Region: PH-like; cl17171
697329008695	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
697329008696	putative FMN binding site [chemical binding]; other site
697329008697	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
697329008698	active site
697329008699	dimer interface [polypeptide binding]; other site
697329008700	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
697329008701	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
697329008702	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
697329008703	FAD binding pocket [chemical binding]; other site
697329008704	FAD binding motif [chemical binding]; other site
697329008705	phosphate binding motif [ion binding]; other site
697329008706	beta-alpha-beta structure motif; other site
697329008707	NAD binding pocket [chemical binding]; other site
697329008708	Iron coordination center [ion binding]; other site
697329008709	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
697329008710	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
697329008711	heterodimer interface [polypeptide binding]; other site
697329008712	active site
697329008713	FMN binding site [chemical binding]; other site
697329008714	homodimer interface [polypeptide binding]; other site
697329008715	substrate binding site [chemical binding]; other site
697329008716	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
697329008717	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
697329008718	dimer interface [polypeptide binding]; other site
697329008719	active site
697329008720	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
697329008721	catalytic residues [active]
697329008722	substrate binding site [chemical binding]; other site
697329008723	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
697329008724	Transposase; Region: DEDD_Tnp_IS110; pfam01548
697329008725	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
697329008726	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
697329008727	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
697329008728	active site
697329008729	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
697329008730	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
697329008731	active site
697329008732	phosphorylation site [posttranslational modification]
697329008733	intermolecular recognition site; other site
697329008734	dimerization interface [polypeptide binding]; other site
697329008735	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
697329008736	DNA binding site [nucleotide binding]
697329008737	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
697329008738	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
697329008739	dimerization interface [polypeptide binding]; other site
697329008740	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
697329008741	dimer interface [polypeptide binding]; other site
697329008742	phosphorylation site [posttranslational modification]
697329008743	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
697329008744	ATP binding site [chemical binding]; other site
697329008745	Mg2+ binding site [ion binding]; other site
697329008746	G-X-G motif; other site
697329008747	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329008748	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329008749	non-specific DNA binding site [nucleotide binding]; other site
697329008750	salt bridge; other site
697329008751	sequence-specific DNA binding site [nucleotide binding]; other site
697329008752	Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis]; Region: COG2348
697329008753	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
697329008754	Clostripain family; Region: Peptidase_C11; pfam03415
697329008755	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
697329008756	EDD domain protein, DegV family; Region: DegV; TIGR00762
697329008757	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
697329008758	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
697329008759	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_2; cd03402
697329008760	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4877
697329008761	Bacterial SH3 domain; Region: SH3_3; pfam08239
697329008762	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
697329008763	Domain of unknown function (DUF1980); Region: DUF1980; cl01492
697329008764	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
697329008765	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
697329008766	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
697329008767	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
697329008768	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
697329008769	acyl-activating enzyme (AAE) consensus motif; other site
697329008770	AMP binding site [chemical binding]; other site
697329008771	active site
697329008772	CoA binding site [chemical binding]; other site
697329008773	Probable beta-xylosidase; Provisional; Region: PLN03080
697329008774	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
697329008775	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
697329008776	Domain of unknown function (DUF4380); Region: DUF4380; pfam14315
697329008777	Cupin domain; Region: Cupin_2; pfam07883
697329008778	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329008779	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329008780	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329008781	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
697329008782	Subunit A of Class III extradiol dioxygenases; Region: Extradiol_Dioxygenase_3A_like; cl06673
697329008783	Tet(M)-like family includes Tet(M), Tet(O), Tet(W), and OtrA, containing tetracycline resistant proteins; Region: TetM_like; cd04168
697329008784	Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis]; Region: FusA; COG0480
697329008785	G1 box; other site
697329008786	putative GEF interaction site [polypeptide binding]; other site
697329008787	GTP/Mg2+ binding site [chemical binding]; other site
697329008788	Switch I region; other site
697329008789	G2 box; other site
697329008790	G3 box; other site
697329008791	Switch II region; other site
697329008792	G4 box; other site
697329008793	G5 box; other site
697329008794	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
697329008795	Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789
697329008796	Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711
697329008797	YacP-like NYN domain; Region: NYN_YacP; pfam05991
697329008798	elongation factor Tu; Reviewed; Region: PRK00049
697329008799	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
697329008800	G1 box; other site
697329008801	GEF interaction site [polypeptide binding]; other site
697329008802	GTP/Mg2+ binding site [chemical binding]; other site
697329008803	Switch I region; other site
697329008804	G2 box; other site
697329008805	G3 box; other site
697329008806	Switch II region; other site
697329008807	G4 box; other site
697329008808	G5 box; other site
697329008809	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
697329008810	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
697329008811	Antibiotic Binding Site [chemical binding]; other site
697329008812	elongation factor G; Reviewed; Region: PRK00007
697329008813	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
697329008814	G1 box; other site
697329008815	putative GEF interaction site [polypeptide binding]; other site
697329008816	GTP/Mg2+ binding site [chemical binding]; other site
697329008817	Switch I region; other site
697329008818	G2 box; other site
697329008819	G3 box; other site
697329008820	Switch II region; other site
697329008821	G4 box; other site
697329008822	G5 box; other site
697329008823	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
697329008824	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
697329008825	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
697329008826	30S ribosomal protein S7; Validated; Region: PRK05302
697329008827	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
697329008828	S17 interaction site [polypeptide binding]; other site
697329008829	S8 interaction site; other site
697329008830	16S rRNA interaction site [nucleotide binding]; other site
697329008831	streptomycin interaction site [chemical binding]; other site
697329008832	23S rRNA interaction site [nucleotide binding]; other site
697329008833	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
697329008834	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
697329008835	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329008836	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
697329008837	DNA binding residues [nucleotide binding]
697329008838	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
697329008839	Beta-lactamase; Region: Beta-lactamase; pfam00144
697329008840	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
697329008841	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
697329008842	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
697329008843	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
697329008844	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
697329008845	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
697329008846	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
697329008847	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
697329008848	G-loop; other site
697329008849	DNA binding site [nucleotide binding]
697329008850	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
697329008851	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
697329008852	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
697329008853	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
697329008854	RPB1 interaction site [polypeptide binding]; other site
697329008855	RPB10 interaction site [polypeptide binding]; other site
697329008856	RPB11 interaction site [polypeptide binding]; other site
697329008857	RPB3 interaction site [polypeptide binding]; other site
697329008858	RPB12 interaction site [polypeptide binding]; other site
697329008859	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
697329008860	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
697329008861	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
697329008862	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
697329008863	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
697329008864	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
697329008865	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
697329008866	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
697329008867	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
697329008868	active site
697329008869	substrate binding site [chemical binding]; other site
697329008870	metal binding site [ion binding]; metal-binding site
697329008871	Protein of unknown function (DUF3782); Region: DUF3782; pfam12644
697329008872	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
697329008873	AlwI restriction endonuclease; Region: RE_AlwI; pfam09491
697329008874	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329008875	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
697329008876	catalytic residues [active]
697329008877	catalytic nucleophile [active]
697329008878	Presynaptic Site I dimer interface [polypeptide binding]; other site
697329008879	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
697329008880	Synaptic Flat tetramer interface [polypeptide binding]; other site
697329008881	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
697329008882	Transposon-encoded protein TnpW; Region: TnpW; pfam14202
697329008883	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
697329008884	Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a...; Region: SR_TndX_transposase; cd03770
697329008885	putative catalytic residues [active]
697329008886	catalytic nucleophile [active]
697329008887	Recombinase; Region: Recombinase; pfam07508
697329008888	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
697329008889	Domain of unknown function (DUF4368); Region: DUF4368; pfam14287
697329008890	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
697329008891	Adenylsuccinate lyase (ASL)_subgroup 2; Region: Adenylsuccinate_lyase_2; cd03302
697329008892	tetramer interface [polypeptide binding]; other site
697329008893	active site
697329008894	Predicted DNA-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG1571
697329008895	Predicted membrane protein (DUF2085); Region: DUF2085; pfam09858
697329008896	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
697329008897	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
697329008898	homodimer interface [polypeptide binding]; other site
697329008899	substrate-cofactor binding pocket; other site
697329008900	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329008901	catalytic residue [active]
697329008902	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
697329008903	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
697329008904	Bacterial sugar transferase; Region: Bac_transf; pfam02397
697329008905	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
697329008906	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
697329008907	putative ATP binding site [chemical binding]; other site
697329008908	putative substrate interface [chemical binding]; other site
697329008909	CotH protein; Region: CotH; pfam08757
697329008910	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
697329008911	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
697329008912	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
697329008913	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
697329008914	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
697329008915	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
697329008916	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
697329008917	substrate binding site [chemical binding]; other site
697329008918	hexamer interface [polypeptide binding]; other site
697329008919	metal binding site [ion binding]; metal-binding site
697329008920	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
697329008921	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
697329008922	putative catalytic cysteine [active]
697329008923	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
697329008924	gamma-glutamyl kinase; Provisional; Region: PRK05429
697329008925	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
697329008926	nucleotide binding site [chemical binding]; other site
697329008927	homotetrameric interface [polypeptide binding]; other site
697329008928	putative phosphate binding site [ion binding]; other site
697329008929	putative allosteric binding site; other site
697329008930	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
697329008931	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329008932	ATP binding site [chemical binding]; other site
697329008933	putative Mg++ binding site [ion binding]; other site
697329008934	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329008935	nucleotide binding region [chemical binding]; other site
697329008936	ATP-binding site [chemical binding]; other site
697329008937	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
697329008938	HRDC domain; Region: HRDC; pfam00570
697329008939	Predicted membrane protein [Function unknown]; Region: COG2323
697329008940	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
697329008941	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
697329008942	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
697329008943	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
697329008944	Chorismate mutase type II; Region: CM_2; smart00830
697329008945	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
697329008946	Prephenate dehydratase; Region: PDT; pfam00800
697329008947	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
697329008948	putative L-Phe binding site [chemical binding]; other site
697329008949	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
697329008950	homotrimer interaction site [polypeptide binding]; other site
697329008951	zinc binding site [ion binding]; other site
697329008952	CDP-binding sites; other site
697329008953	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329008954	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329008955	Coenzyme A binding pocket [chemical binding]; other site
697329008956	bidirectional hydrogenase complex protein HoxU; Validated; Region: PRK07569
697329008957	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
697329008958	catalytic loop [active]
697329008959	iron binding site [ion binding]; other site
697329008960	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
697329008961	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
697329008962	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
697329008963	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
697329008964	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
697329008965	dimer interface [polypeptide binding]; other site
697329008966	[2Fe-2S] cluster binding site [ion binding]; other site
697329008967	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
697329008968	SLBB domain; Region: SLBB; pfam10531
697329008969	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
697329008970	4Fe-4S binding domain; Region: Fer4; pfam00037
697329008971	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
697329008972	4Fe-4S binding domain; Region: Fer4_6; pfam12837
697329008973	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
697329008974	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
697329008975	putative dimer interface [polypeptide binding]; other site
697329008976	[2Fe-2S] cluster binding site [ion binding]; other site
697329008977	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
697329008978	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
697329008979	catalytic core [active]
697329008980	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
697329008981	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329008982	Coenzyme A binding pocket [chemical binding]; other site
697329008983	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
697329008984	putative active site [active]
697329008985	dimerization interface [polypeptide binding]; other site
697329008986	putative tRNAtyr binding site [nucleotide binding]; other site
697329008987	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
697329008988	active site
697329008989	catalytic residues [active]
697329008990	Haemolysin-III related; Region: HlyIII; cl03831
697329008991	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329008992	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329008993	metal binding site [ion binding]; metal-binding site
697329008994	active site
697329008995	I-site; other site
697329008996	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
697329008997	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
697329008998	MPN+ (JAMM) motif; other site
697329008999	Zinc-binding site [ion binding]; other site
697329009000	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
697329009001	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
697329009002	homodimer interface [polypeptide binding]; other site
697329009003	substrate-cofactor binding pocket; other site
697329009004	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329009005	catalytic residue [active]
697329009006	Transcriptional regulator [Transcription]; Region: LysR; COG0583
697329009007	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
697329009008	LysR substrate binding domain; Region: LysR_substrate; pfam03466
697329009009	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
697329009010	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
697329009011	active site
697329009012	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
697329009013	active site
697329009014	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
697329009015	active site
697329009016	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
697329009017	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
697329009018	G1 box; other site
697329009019	putative GEF interaction site [polypeptide binding]; other site
697329009020	GTP/Mg2+ binding site [chemical binding]; other site
697329009021	Switch I region; other site
697329009022	G2 box; other site
697329009023	G3 box; other site
697329009024	Switch II region; other site
697329009025	G4 box; other site
697329009026	G5 box; other site
697329009027	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
697329009028	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
697329009029	Phosphotransferase enzyme family; Region: APH; pfam01636
697329009030	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
697329009031	active site
697329009032	ATP binding site [chemical binding]; other site
697329009033	SpoVA protein; Region: SpoVA; cl04298
697329009034	Predicted transcriptional regulators [Transcription]; Region: COG1695
697329009035	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
697329009036	Predicted membrane protein [Function unknown]; Region: COG4709
697329009037	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
697329009038	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
697329009039	CAAX protease self-immunity; Region: Abi; pfam02517
697329009040	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
697329009041	PspC domain; Region: PspC; pfam04024
697329009042	PspC domain; Region: PspC; pfam04024
697329009043	LicD family; Region: LicD; cl01378
697329009044	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
697329009045	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
697329009046	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
697329009047	substrate binding site; other site
697329009048	dimer interface; other site
697329009049	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
697329009050	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329009051	Coenzyme A binding pocket [chemical binding]; other site
697329009052	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
697329009053	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
697329009054	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
697329009055	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
697329009056	Walker A/P-loop; other site
697329009057	ATP binding site [chemical binding]; other site
697329009058	Q-loop/lid; other site
697329009059	ABC transporter signature motif; other site
697329009060	Walker B; other site
697329009061	D-loop; other site
697329009062	H-loop/switch region; other site
697329009063	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
697329009064	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
697329009065	Walker A/P-loop; other site
697329009066	ATP binding site [chemical binding]; other site
697329009067	Q-loop/lid; other site
697329009068	ABC transporter signature motif; other site
697329009069	Walker B; other site
697329009070	D-loop; other site
697329009071	H-loop/switch region; other site
697329009072	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329009073	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
697329009074	Protein of unknown function DUF58; Region: DUF58; pfam01882
697329009075	MoxR-like ATPases [General function prediction only]; Region: COG0714
697329009076	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
697329009077	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cd00688
697329009078	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
697329009079	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
697329009080	Trp docking motif [polypeptide binding]; other site
697329009081	active site
697329009082	Protein of unknown function (DUF1273); Region: DUF1273; cl01859
697329009083	Transcriptional regulator [Transcription]; Region: LytR; COG1316
697329009084	ribosome maturation protein RimP; Reviewed; Region: PRK00092
697329009085	Sm and related proteins; Region: Sm_like; cl00259
697329009086	heptamer interface [polypeptide binding]; other site
697329009087	Sm1 motif; other site
697329009088	hexamer interface [polypeptide binding]; other site
697329009089	RNA binding site [nucleotide binding]; other site
697329009090	Sm2 motif; other site
697329009091	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
697329009092	NusA N-terminal domain; Region: NusA_N; pfam08529
697329009093	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
697329009094	RNA binding site [nucleotide binding]; other site
697329009095	homodimer interface [polypeptide binding]; other site
697329009096	NusA-like KH domain; Region: KH_5; pfam13184
697329009097	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
697329009098	G-X-X-G motif; other site
697329009099	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
697329009100	putative RNA binding cleft [nucleotide binding]; other site
697329009101	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
697329009102	translation initiation factor IF-2; Region: IF-2; TIGR00487
697329009103	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
697329009104	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
697329009105	G1 box; other site
697329009106	putative GEF interaction site [polypeptide binding]; other site
697329009107	GTP/Mg2+ binding site [chemical binding]; other site
697329009108	Switch I region; other site
697329009109	G2 box; other site
697329009110	G3 box; other site
697329009111	Switch II region; other site
697329009112	G4 box; other site
697329009113	G5 box; other site
697329009114	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
697329009115	Translation-initiation factor 2; Region: IF-2; pfam11987
697329009116	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
697329009117	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329009118	Coenzyme A binding pocket [chemical binding]; other site
697329009119	Ribosome-binding factor A; Region: RBFA; pfam02033
697329009120	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
697329009121	DHH family; Region: DHH; pfam01368
697329009122	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
697329009123	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
697329009124	RNA binding site [nucleotide binding]; other site
697329009125	active site
697329009126	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
697329009127	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
697329009128	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
697329009129	active site
697329009130	Riboflavin kinase; Region: Flavokinase; pfam01687
697329009131	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
697329009132	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
697329009133	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
697329009134	Walker A/P-loop; other site
697329009135	ATP binding site [chemical binding]; other site
697329009136	Q-loop/lid; other site
697329009137	ABC transporter signature motif; other site
697329009138	Walker B; other site
697329009139	D-loop; other site
697329009140	H-loop/switch region; other site
697329009141	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
697329009142	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
697329009143	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
697329009144	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
697329009145	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
697329009146	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
697329009147	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
697329009148	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
697329009149	FMN binding site [chemical binding]; other site
697329009150	active site
697329009151	catalytic residues [active]
697329009152	substrate binding site [chemical binding]; other site
697329009153	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
697329009154	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
697329009155	NAD(P) binding site [chemical binding]; other site
697329009156	active site
697329009157	AzlC protein; Region: AzlC; pfam03591
697329009158	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
697329009159	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
697329009160	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
697329009161	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
697329009162	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329009163	I-site; other site
697329009164	active site
697329009165	metal binding site [ion binding]; metal-binding site
697329009166	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
697329009167	Rubredoxin; Region: Rubredoxin; pfam00301
697329009168	iron binding site [ion binding]; other site
697329009169	rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046
697329009170	Rubrerythrin [Energy production and conversion]; Region: COG1592
697329009171	diiron binding motif [ion binding]; other site
697329009172	threonine dehydratase; Provisional; Region: PRK08198
697329009173	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
697329009174	tetramer interface [polypeptide binding]; other site
697329009175	pyridoxal 5'-phosphate binding site [chemical binding]; other site
697329009176	catalytic residue [active]
697329009177	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
697329009178	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
697329009179	nudix motif; other site
697329009180	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
697329009181	homotrimer interaction site [polypeptide binding]; other site
697329009182	putative active site [active]
697329009183	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
697329009184	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
697329009185	ribonuclease Y; Region: RNase_Y; TIGR03319
697329009186	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329009187	Zn2+ binding site [ion binding]; other site
697329009188	Mg2+ binding site [ion binding]; other site
697329009189	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
697329009190	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
697329009191	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
697329009192	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
697329009193	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
697329009194	active site
697329009195	dimer interface [polypeptide binding]; other site
697329009196	motif 1; other site
697329009197	motif 2; other site
697329009198	motif 3; other site
697329009199	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
697329009200	anticodon binding site; other site
697329009201	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
697329009202	MraZ protein; Region: MraZ; pfam02381
697329009203	cell division protein MraZ; Reviewed; Region: PRK00326
697329009204	MraZ protein; Region: MraZ; pfam02381
697329009205	MraW methylase family; Region: Methyltransf_5; pfam01795
697329009206	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
697329009207	Cell division protein FtsL; Region: FtsL; cl11433
697329009208	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
697329009209	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
697329009210	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
697329009211	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
697329009212	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
697329009213	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
697329009214	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
697329009215	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
697329009216	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
697329009217	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
697329009218	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
697329009219	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
697329009220	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
697329009221	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
697329009222	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
697329009223	putative catalytic motif [active]
697329009224	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
697329009225	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
697329009226	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
697329009227	active site
697329009228	homodimer interface [polypeptide binding]; other site
697329009229	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
697329009230	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
697329009231	hinge; other site
697329009232	active site
697329009233	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
697329009234	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
697329009235	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
697329009236	nucleotide binding site [chemical binding]; other site
697329009237	SulA interaction site; other site
697329009238	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
697329009239	Fumarase C-terminus; Region: Fumerase_C; cl00795
697329009240	SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; Region: SERPIN; cl00137
697329009241	reactive center loop; other site
697329009242	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
697329009243	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
697329009244	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
697329009245	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
697329009246	putative ligand binding site [chemical binding]; other site
697329009247	putative NAD binding site [chemical binding]; other site
697329009248	catalytic site [active]
697329009249	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
697329009250	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329009251	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329009252	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826
697329009253	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
697329009254	active site
697329009255	PHP Thumb interface [polypeptide binding]; other site
697329009256	metal binding site [ion binding]; metal-binding site
697329009257	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
697329009258	generic binding surface I; other site
697329009259	generic binding surface II; other site
697329009260	Acyltransferase family; Region: Acyl_transf_3; pfam01757
697329009261	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
697329009262	S-adenosylmethionine synthetase; Validated; Region: PRK05250
697329009263	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
697329009264	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
697329009265	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
697329009266	L-fucose isomerase and related proteins [Carbohydrate transport and metabolism]; Region: FucI; COG2407
697329009267	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
697329009268	hexamer (dimer of trimers) interface [polypeptide binding]; other site
697329009269	substrate binding site [chemical binding]; other site
697329009270	trimer interface [polypeptide binding]; other site
697329009271	Mn binding site [ion binding]; other site
697329009272	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
697329009273	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
697329009274	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
697329009275	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
697329009276	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
697329009277	23S rRNA binding site [nucleotide binding]; other site
697329009278	L21 binding site [polypeptide binding]; other site
697329009279	L13 binding site [polypeptide binding]; other site
697329009280	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
697329009281	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
697329009282	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
697329009283	DNA protecting protein DprA; Region: dprA; TIGR00732
697329009284	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
697329009285	DNA topoisomerase I; Validated; Region: PRK05582
697329009286	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
697329009287	active site
697329009288	interdomain interaction site; other site
697329009289	putative metal-binding site [ion binding]; other site
697329009290	nucleotide binding site [chemical binding]; other site
697329009291	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
697329009292	domain I; other site
697329009293	DNA binding groove [nucleotide binding]
697329009294	phosphate binding site [ion binding]; other site
697329009295	domain II; other site
697329009296	domain III; other site
697329009297	nucleotide binding site [chemical binding]; other site
697329009298	catalytic site [active]
697329009299	domain IV; other site
697329009300	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
697329009301	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
697329009302	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
697329009303	Coenzyme A binding pocket [chemical binding]; other site
697329009304	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
697329009305	Glucose inhibited division protein A; Region: GIDA; pfam01134
697329009306	putative phosphate acyltransferase; Provisional; Region: PRK05331
697329009307	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
697329009308	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
697329009309	dimerization interface [polypeptide binding]; other site
697329009310	active site
697329009311	metal binding site [ion binding]; metal-binding site
697329009312	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
697329009313	dsRNA binding site [nucleotide binding]; other site
697329009314	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
697329009315	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
697329009316	FeS/SAM binding site; other site
697329009317	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
697329009318	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
697329009319	Walker A/P-loop; other site
697329009320	ATP binding site [chemical binding]; other site
697329009321	Q-loop/lid; other site
697329009322	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
697329009323	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
697329009324	ABC transporter signature motif; other site
697329009325	Walker B; other site
697329009326	D-loop; other site
697329009327	H-loop/switch region; other site
697329009328	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
697329009329	putative active site [active]
697329009330	nucleotide binding site [chemical binding]; other site
697329009331	nudix motif; other site
697329009332	putative metal binding site [ion binding]; other site
697329009333	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
697329009334	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
697329009335	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
697329009336	P loop; other site
697329009337	GTP binding site [chemical binding]; other site
697329009338	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
697329009339	active site
697329009340	dimerization interface [polypeptide binding]; other site
697329009341	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
697329009342	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
697329009343	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
697329009344	active site
697329009345	(T/H)XGH motif; other site
697329009346	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
697329009347	Zn2+ binding site [ion binding]; other site
697329009348	Mg2+ binding site [ion binding]; other site
697329009349	Oligomerisation domain; Region: Oligomerisation; pfam02410
697329009350	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
697329009351	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
697329009352	HIGH motif; other site
697329009353	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
697329009354	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
697329009355	active site
697329009356	KMSKS motif; other site
697329009357	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
697329009358	tRNA binding surface [nucleotide binding]; other site
697329009359	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
697329009360	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
697329009361	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
697329009362	active site
697329009363	Predicted methyltransferases [General function prediction only]; Region: COG0313
697329009364	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
697329009365	putative SAM binding site [chemical binding]; other site
697329009366	putative homodimer interface [polypeptide binding]; other site
697329009367	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329009368	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329009369	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
697329009370	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
697329009371	motif II; other site
697329009372	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
697329009373	active site
697329009374	putative substrate binding region [chemical binding]; other site
697329009375	Biotin operon repressor [Transcription]; Region: BirA; COG1654
697329009376	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
697329009377	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
697329009378	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
697329009379	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
697329009380	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
697329009381	active site
697329009382	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
697329009383	active site
697329009384	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase (HisA) and the cyclase subunit of imidazoleglycerol phosphate synthase (HisF). The ProFAR isomerase catalyzes the fourth step in histidine biosynthesis, an...; Region: HisA_HisF; cd04723
697329009385	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
697329009386	active site
697329009387	aconitate hydratase; Validated; Region: PRK07229
697329009388	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Bact; cd01585
697329009389	substrate binding site [chemical binding]; other site
697329009390	ligand binding site [chemical binding]; other site
697329009391	Bacterial Aconitase-like swivel domain. Aconitase (aconitate hydratase or citrate hydrolyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle.  Cis-aconitate is formed as an intermediate product during the course...; Region: AcnA_Bact_Swivel; cd01579
697329009392	substrate binding site [chemical binding]; other site
697329009393	isocitrate dehydrogenase; Validated; Region: PRK08299
697329009394	Protein of unknown function (DUF1292); Region: DUF1292; pfam06949
697329009395	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
697329009396	Hydroxyethylphosphoate dehydrogenase (HEPD) catalyzes the reduction of phosphonoacetaldehyde (PnAA) to hydroxyethylphosphoate (HEP); Region: HEPD; cd08182
697329009397	putative active site [active]
697329009398	metal binding site [ion binding]; metal-binding site
697329009399	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
697329009400	DNA-binding site [nucleotide binding]; DNA binding site
697329009401	Transcriptional regulators [Transcription]; Region: PurR; COG1609
697329009402	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
697329009403	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
697329009404	L-aspartate oxidase; Provisional; Region: PRK06175
697329009405	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
697329009406	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
697329009407	dimerization interface [polypeptide binding]; other site
697329009408	active site
697329009409	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
697329009410	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
697329009411	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
697329009412	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
697329009413	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
697329009414	Double zinc ribbon; Region: DZR; pfam12773
697329009415	hypothetical protein; Provisional; Region: PRK06761
697329009416	Fibrobacter succinogenes paralogous family TIGR02172; Region: Fb_sc_TIGR02172
697329009417	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
697329009418	substrate binding site [chemical binding]; other site
697329009419	peptidyl-prolyl isomerase, gliding motility-associated; Region: ppisom_GldI; TIGR03516
697329009420	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
697329009421	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
697329009422	putative active site [active]
697329009423	catalytic residue [active]
697329009424	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
697329009425	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
697329009426	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
697329009427	ATP binding site [chemical binding]; other site
697329009428	putative Mg++ binding site [ion binding]; other site
697329009429	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329009430	nucleotide binding region [chemical binding]; other site
697329009431	ATP-binding site [chemical binding]; other site
697329009432	TRCF domain; Region: TRCF; pfam03461
697329009433	Probable zinc-binding domain; Region: zf-trcl; pfam13451
697329009434	CxxC-x17-CxxC domain; Region: cxxc_cxxc_Mbark; TIGR04272
697329009435	RNA polymerase factor sigma-70; Validated; Region: PRK08295
697329009436	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
697329009437	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
697329009438	DNA binding residues [nucleotide binding]
697329009439	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
697329009440	Glucosyl transferase GtrII; Region: Glucos_trans_II; cl10304
697329009441	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
697329009442	dimer interface [polypeptide binding]; other site
697329009443	ADP-ribose binding site [chemical binding]; other site
697329009444	active site
697329009445	nudix motif; other site
697329009446	metal binding site [ion binding]; metal-binding site
697329009447	DHHW protein; Region: DHHW; pfam14286
697329009448	DHHW protein; Region: DHHW; pfam14286
697329009449	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
697329009450	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
697329009451	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
697329009452	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
697329009453	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
697329009454	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
697329009455	dimer interface [polypeptide binding]; other site
697329009456	active site
697329009457	CoA binding pocket [chemical binding]; other site
697329009458	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
697329009459	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
697329009460	motif I; other site
697329009461	active site
697329009462	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
697329009463	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
697329009464	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
697329009465	FMN binding site [chemical binding]; other site
697329009466	substrate binding site [chemical binding]; other site
697329009467	putative catalytic residue [active]
697329009468	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
697329009469	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
697329009470	NAD(P) binding site [chemical binding]; other site
697329009471	homotetramer interface [polypeptide binding]; other site
697329009472	homodimer interface [polypeptide binding]; other site
697329009473	active site
697329009474	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
697329009475	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
697329009476	dimer interface [polypeptide binding]; other site
697329009477	active site
697329009478	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
697329009479	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
697329009480	carboxyltransferase (CT) interaction site; other site
697329009481	biotinylation site [posttranslational modification]; other site
697329009482	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
697329009483	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
697329009484	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
697329009485	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
697329009486	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
697329009487	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
697329009488	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
697329009489	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
697329009490	acyl carrier protein; Provisional; Region: acpP; PRK00982
697329009491	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329009492	putative metal binding site [ion binding]; other site
697329009493	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
697329009494	FtsX-like permease family; Region: FtsX; pfam02687
697329009495	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
697329009496	FtsX-like permease family; Region: FtsX; pfam02687
697329009497	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
697329009498	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
697329009499	HlyD family secretion protein; Region: HlyD_3; pfam13437
697329009500	putative membrane fusion protein; Region: TIGR02828
697329009501	homoserine dehydrogenase; Provisional; Region: PRK06349
697329009502	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
697329009503	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
697329009504	hypothetical protein; Provisional; Region: PRK04435
697329009505	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
697329009506	DNA-binding interface [nucleotide binding]; DNA binding site
697329009507	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
697329009508	probable non-F420 flavinoid oxidoreductase; Region: flavin_revert; TIGR03885
697329009509	Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527
697329009510	V-type ATP synthase subunit C; Provisional; Region: PRK01198; cl00660
697329009511	V-type ATP synthase subunit I; Validated; Region: PRK05771
697329009512	ATP synthase subunit C; Region: ATP-synt_C; cl00466
697329009513	ATP synthase (F/14-kDa) subunit; Region: ATP-synt_F; pfam01990
697329009514	Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; Region: NtpE; COG1390
697329009515	V-type ATP synthase subunit E; Provisional; Region: PRK03963; cl17074
697329009516	V-type ATP synthase subunit A; Provisional; Region: PRK04192
697329009517	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
697329009518	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
697329009519	Walker A motif/ATP binding site; other site
697329009520	Walker B motif; other site
697329009521	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
697329009522	ATP synthase subunit D; Region: ATP-synt_D; pfam01813
697329009523	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
697329009524	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
697329009525	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
697329009526	catalytic residues [active]
697329009527	dimer interface [polypeptide binding]; other site
697329009528	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
697329009529	MarR family; Region: MarR; pfam01047
697329009530	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
697329009531	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
697329009532	catalytic residues [active]
697329009533	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
697329009534	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
697329009535	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
697329009536	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
697329009537	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
697329009538	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
697329009539	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329009540	S-adenosylmethionine binding site [chemical binding]; other site
697329009541	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
697329009542	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
697329009543	putative catalytic cysteine [active]
697329009544	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
697329009545	putative active site [active]
697329009546	metal binding site [ion binding]; metal-binding site
697329009547	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
697329009548	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
697329009549	putative active site [active]
697329009550	putative metal binding site [ion binding]; other site
697329009551	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
697329009552	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329009553	dimer interface [polypeptide binding]; other site
697329009554	conserved gate region; other site
697329009555	putative PBP binding loops; other site
697329009556	ABC-ATPase subunit interface; other site
697329009557	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
697329009558	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329009559	ABC-ATPase subunit interface; other site
697329009560	putative PBP binding loops; other site
697329009561	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
697329009562	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329009563	dimer interface [polypeptide binding]; other site
697329009564	conserved gate region; other site
697329009565	ABC-ATPase subunit interface; other site
697329009566	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
697329009567	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
697329009568	dimer interface [polypeptide binding]; other site
697329009569	conserved gate region; other site
697329009570	putative PBP binding loops; other site
697329009571	ABC-ATPase subunit interface; other site
697329009572	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329009573	putative metal binding site [ion binding]; other site
697329009574	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
697329009575	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
697329009576	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
697329009577	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329009578	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329009579	Walker A/P-loop; other site
697329009580	ATP binding site [chemical binding]; other site
697329009581	Q-loop/lid; other site
697329009582	ABC transporter signature motif; other site
697329009583	Walker B; other site
697329009584	D-loop; other site
697329009585	H-loop/switch region; other site
697329009586	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
697329009587	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
697329009588	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
697329009589	Walker A/P-loop; other site
697329009590	ATP binding site [chemical binding]; other site
697329009591	Q-loop/lid; other site
697329009592	ABC transporter signature motif; other site
697329009593	Walker B; other site
697329009594	D-loop; other site
697329009595	H-loop/switch region; other site
697329009596	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329009597	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
697329009598	EF-hand domain pair; Region: EF_hand_5; pfam13499
697329009599	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
697329009600	dimer interface [polypeptide binding]; other site
697329009601	pyridoxal binding site [chemical binding]; other site
697329009602	ATP binding site [chemical binding]; other site
697329009603	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
697329009604	Protein of unknown function (DUF2581); Region: DUF2581; pfam10756
697329009605	EDD domain protein, DegV family; Region: DegV; TIGR00762
697329009606	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
697329009607	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
697329009608	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
697329009609	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
697329009610	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
697329009611	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
697329009612	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
697329009613	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
697329009614	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
697329009615	Coenzyme A binding pocket [chemical binding]; other site
697329009616	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
697329009617	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
697329009618	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
697329009619	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
697329009620	active site
697329009621	AAA domain; Region: AAA_17; cl17253
697329009622	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
697329009623	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
697329009624	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
697329009625	homodimer interface [polypeptide binding]; other site
697329009626	NADP binding site [chemical binding]; other site
697329009627	substrate binding site [chemical binding]; other site
697329009628	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
697329009629	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
697329009630	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
697329009631	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
697329009632	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
697329009633	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
697329009634	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
697329009635	metal binding site [ion binding]; metal-binding site
697329009636	active site
697329009637	I-site; other site
697329009638	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
697329009639	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
697329009640	P-loop; other site
697329009641	Magnesium ion binding site [ion binding]; other site
697329009642	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
697329009643	Magnesium ion binding site [ion binding]; other site
697329009644	ParB-like nuclease domain; Region: ParB; smart00470
697329009645	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
697329009646	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
697329009647	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
697329009648	active site
697329009649	catalytic site [active]
697329009650	substrate binding site [chemical binding]; other site
697329009651	Protein of unknown function (DUF3848); Region: DUF3848; pfam12959
697329009652	Protein of unknown function (DUF3849); Region: DUF3849; pfam12960
697329009653	Cna protein B-type domain; Region: Cna_B; pfam05738
697329009654	Cna protein B-type domain; Region: Cna_B; pfam05738
697329009655	Cna protein B-type domain; Region: Cna_B; pfam05738
697329009656	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
697329009657	putative active site [active]
697329009658	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
697329009659	SpoVG; Region: SpoVG; cl00915
697329009660	SpoVG; Region: SpoVG; cl00915
697329009661	MutS domain I; Region: MutS_I; pfam01624
697329009662	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
697329009663	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
697329009664	S-adenosylmethionine binding site [chemical binding]; other site
697329009665	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
697329009666	DEAD-like helicases superfamily; Region: DEXDc; smart00487
697329009667	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
697329009668	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
697329009669	nucleotide binding region [chemical binding]; other site
697329009670	ATP-binding site [chemical binding]; other site
697329009671	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
697329009672	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
697329009673	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
697329009674	Toprim-like; Region: Toprim_2; pfam13155
697329009675	active site
697329009676	metal binding site [ion binding]; metal-binding site
697329009677	AAA-like domain; Region: AAA_10; pfam12846
697329009678	Domain of unknown function DUF87; Region: DUF87; pfam01935
697329009679	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
697329009680	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
697329009681	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
697329009682	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
697329009683	Sel1-like repeats; Region: SEL1; smart00671
697329009684	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
697329009685	Sel1-like repeats; Region: SEL1; smart00671
697329009686	Sel1-like repeats; Region: SEL1; smart00671
697329009687	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
697329009688	Walker A motif; other site
697329009689	ATP binding site [chemical binding]; other site
697329009690	Walker B motif; other site
697329009691	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
697329009692	non-specific DNA interactions [nucleotide binding]; other site
697329009693	DNA binding site [nucleotide binding]
697329009694	sequence specific DNA binding site [nucleotide binding]; other site
697329009695	putative cAMP binding site [chemical binding]; other site
697329009696	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
697329009697	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
697329009698	non-specific DNA binding site [nucleotide binding]; other site
697329009699	salt bridge; other site
697329009700	sequence-specific DNA binding site [nucleotide binding]; other site
697329009701	DNA topoisomerase III; Provisional; Region: PRK07726
697329009702	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
697329009703	active site
697329009704	putative interdomain interaction site [polypeptide binding]; other site
697329009705	putative metal-binding site [ion binding]; other site
697329009706	putative nucleotide binding site [chemical binding]; other site
697329009707	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
697329009708	domain I; other site
697329009709	DNA binding groove [nucleotide binding]
697329009710	phosphate binding site [ion binding]; other site
697329009711	domain II; other site
697329009712	domain III; other site
697329009713	nucleotide binding site [chemical binding]; other site
697329009714	catalytic site [active]
697329009715	domain IV; other site
697329009716	Arc-like DNA binding domain; Region: Arc; pfam03869
697329009717	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
697329009718	trehalose-6-phosphate synthase; Provisional; Region: PRK10117
697329009719	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
697329009720	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
697329009721	Int/Topo IB signature motif; other site
697329009722	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
697329009723	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
697329009724	Putative catalytic domain, repeat 1, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_1; cd09154
697329009725	putative active site [active]
697329009726	catalytic site [active]
697329009727	Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_2; cd09160
697329009728	putative active site [active]
697329009729	catalytic site [active]
697329009730	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
697329009731	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
697329009732	putative active site [active]
697329009733	putative metal binding site [ion binding]; other site
697329009734	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
697329009735	conserved cys residue [active]
697329009736	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
697329009737	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
697329009738	G-X-X-G motif; other site
697329009739	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
697329009740	RxxxH motif; other site
697329009741	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
697329009742	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
697329009743	Haemolytic domain; Region: Haemolytic; pfam01809
697329009744	ribonuclease P; Reviewed; Region: rnpA; PRK00499
697329009745	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399