-- dump date 20140620_033654 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001491739.1 157803190 5626507 1..822 1 NC_009879.1 COG1806 Uncharacterized protein conserved in bacteria; hypothetical protein 822 5626507 A1E_00005 Rickettsia canadensis str. McKiel hypothetical protein YP_001491739.1 1 D 293613 CDS YP_001491740.1 157803191 5626202 1065..1382 1 NC_009879.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 1382 5626202 A1E_00010 Rickettsia canadensis str. McKiel thioredoxin YP_001491740.1 1065 D 293613 CDS YP_001491741.1 157803192 5626203 1375..2136 1 NC_009879.1 COG1129 ABC-type sugar transport system, ATPase component; O-antigen export system ATP-binding protein RfbE 2136 5626203 A1E_00015 Rickettsia canadensis str. McKiel O-antigen export system ATP-binding protein RfbE YP_001491741.1 1375 D 293613 CDS YP_001491742.1 157803193 5626204 2295..3071 1 NC_009879.1 hypothetical protein 3071 5626204 A1E_00020 Rickettsia canadensis str. McKiel hypothetical protein YP_001491742.1 2295 D 293613 CDS YP_001491743.1 157803194 5626205 3068..6214 1 NC_009879.1 undetermined function; putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase 6214 5626205 A1E_00025 Rickettsia canadensis str. McKiel putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase YP_001491743.1 3068 D 293613 CDS YP_001491744.1 157803195 5626206 complement(6333..7127) 1 NC_009879.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 7127 5626206 A1E_00030 Rickettsia canadensis str. McKiel UDP-N-acetylglucosamine acyltransferase YP_001491744.1 6333 R 293613 CDS YP_001491745.1 157803196 5626207 complement(7135..7569) 1 NC_009879.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 7569 fabZ 5626207 fabZ Rickettsia canadensis str. McKiel (3R)-hydroxymyristoyl-ACP dehydratase YP_001491745.1 7135 R 293613 CDS YP_001491746.1 157803197 5626513 complement(7570..8598) 1 NC_009879.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 8598 lpxD 5626513 lpxD Rickettsia canadensis str. McKiel UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001491746.1 7570 R 293613 CDS YP_001491747.1 157803198 5626515 8865..9845 1 NC_009879.1 COG0042 tRNA-dihydrouridine synthase; nifR3-like protein 9845 5626515 A1E_00045 Rickettsia canadensis str. McKiel nifR3-like protein YP_001491747.1 8865 D 293613 CDS YP_001491748.1 157803199 5626516 complement(10469..10900) 1 NC_009879.1 COG0802 Predicted ATPase or kinase; hypothetical protein 10900 5626516 A1E_00050 Rickettsia canadensis str. McKiel hypothetical protein YP_001491748.1 10469 R 293613 CDS YP_001491749.1 157803200 5626517 complement(10891..11694) 1 NC_009879.1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; zinc/manganese ABC transporter substrate binding protein 11694 5626517 A1E_00055 Rickettsia canadensis str. McKiel zinc/manganese ABC transporter substrate binding protein YP_001491749.1 10891 R 293613 CDS YP_001491750.1 157803201 5626518 complement(11798..13009) 1 NC_009879.1 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; poly(A) polymerase 13009 5626518 A1E_00060 Rickettsia canadensis str. McKiel poly(A) polymerase YP_001491750.1 11798 R 293613 CDS YP_001491751.1 157803202 5625864 complement(13738..14010) 1 NC_009879.1 ComEC/Rec2-related protein 14010 5625864 A1E_00065 Rickettsia canadensis str. McKiel ComEC/Rec2-related protein YP_001491751.1 13738 R 293613 CDS YP_001491752.1 157803203 5625865 14292..14453 1 NC_009879.1 hypothetical protein 14453 5625865 A1E_00070 Rickettsia canadensis str. McKiel hypothetical protein YP_001491752.1 14292 D 293613 CDS YP_001491753.1 157803204 5625866 14710..19161 1 NC_009879.1 cell surface antigen Sca1 19161 5625866 A1E_00075 Rickettsia canadensis str. McKiel cell surface antigen Sca1 YP_001491753.1 14710 D 293613 CDS YP_001491754.1 157803205 5625868 19742..20143 1 NC_009879.1 COG0658 Predicted membrane metal-binding protein; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 20143 lpxD 5625868 lpxD Rickettsia canadensis str. McKiel UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001491754.1 19742 D 293613 CDS YP_001491755.1 157803206 5626412 complement(21912..22403) 1 NC_009879.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 22403 5626412 A1E_00085 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit B YP_001491755.1 21912 R 293613 CDS YP_001491756.1 157803207 5626413 complement(22403..22870) 1 NC_009879.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 22870 5626413 A1E_00090 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit B' YP_001491756.1 22403 R 293613 CDS YP_001491757.1 157803208 5626414 complement(22888..23112) 1 NC_009879.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 23112 5626414 A1E_00095 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit C YP_001491757.1 22888 R 293613 CDS YP_001491758.1 157803209 5626415 complement(23287..24015) 1 NC_009879.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 24015 5626415 A1E_00100 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit A YP_001491758.1 23287 R 293613 CDS YP_001491759.1 157803210 5626416 complement(24020..24283) 1 NC_009879.1 COG5336 Uncharacterized protein conserved in bacteria; hypothetical protein 24283 5626416 A1E_00105 Rickettsia canadensis str. McKiel hypothetical protein YP_001491759.1 24020 R 293613 CDS YP_001491760.1 157803211 5626003 complement(24453..25277) 1 NC_009879.1 COG1651 Protein-disulfide isomerase; protein-disulfide isomerase 25277 5626003 A1E_00110 Rickettsia canadensis str. McKiel protein-disulfide isomerase YP_001491760.1 24453 R 293613 CDS YP_001491761.1 157803212 5626004 25444..25971 1 NC_009879.1 COG1329 Transcriptional regulators, similar to M. xanthus CarD; hypothetical protein 25971 5626004 A1E_00115 Rickettsia canadensis str. McKiel hypothetical protein YP_001491761.1 25444 D 293613 CDS YP_001491762.1 157803213 5626005 complement(26180..27784) 1 NC_009879.1 COG0500 SAM-dependent methyltransferases; F0F1 ATP synthase subunit A 27784 5626005 A1E_00120 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit A YP_001491762.1 26180 R 293613 CDS YP_001491763.1 157803214 5626006 complement(27939..29021) 1 NC_009879.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 29021 recF 5626006 recF Rickettsia canadensis str. McKiel recombination protein F YP_001491763.1 27939 R 293613 CDS YP_001491764.1 157803215 5626007 complement(29046..29714) 1 NC_009879.1 recombination protein F 29714 recF 5626007 recF Rickettsia canadensis str. McKiel recombination protein F YP_001491764.1 29046 R 293613 CDS YP_001491765.1 157803216 5626208 complement(29838..29927) 1 NC_009879.1 COG1195 Recombinational DNA repair ATPase (RecF pathway); hypothetical protein 29927 5626208 A1E_00135 Rickettsia canadensis str. McKiel hypothetical protein YP_001491765.1 29838 R 293613 CDS YP_001491766.1 157803217 5626209 complement(31347..31916) 1 NC_009879.1 COG1678 Putative transcriptional regulator; hypothetical protein 31916 5626209 A1E_00140 Rickettsia canadensis str. McKiel hypothetical protein YP_001491766.1 31347 R 293613 CDS YP_001491767.1 157803218 5626210 31988..32626 1 NC_009879.1 hypothetical protein 32626 5626210 A1E_00145 Rickettsia canadensis str. McKiel hypothetical protein YP_001491767.1 31988 D 293613 CDS YP_001491768.1 157803219 5626211 33032..33145 1 NC_009879.1 hypothetical protein 33145 5626211 A1E_00150 Rickettsia canadensis str. McKiel hypothetical protein YP_001491768.1 33032 D 293613 CDS YP_001491769.1 157803220 5626212 complement(33425..34747) 1 NC_009879.1 hypothetical protein 34747 5626212 A1E_00155 Rickettsia canadensis str. McKiel hypothetical protein YP_001491769.1 33425 R 293613 CDS YP_001491770.1 157803221 5626743 complement(34766..34900) 1 NC_009879.1 COG1286 Uncharacterized membrane protein, required for colicin V production; hypothetical protein 34900 5626743 A1E_00160 Rickettsia canadensis str. McKiel hypothetical protein YP_001491770.1 34766 R 293613 CDS YP_001491771.1 157803222 5626744 36670..39246 1 NC_009879.1 clpB protein 39246 5626744 A1E_00165 Rickettsia canadensis str. McKiel clpB protein YP_001491771.1 36670 D 293613 CDS YP_001491772.1 157803223 5626745 complement(39386..39874) 1 NC_009879.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 39874 5626745 A1E_00170 Rickettsia canadensis str. McKiel hypothetical protein YP_001491772.1 39386 R 293613 CDS YP_001491773.1 157803224 5626746 complement(40067..41095) 1 NC_009879.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 41095 5626746 A1E_00175 Rickettsia canadensis str. McKiel putative DNA-binding/iron metalloprotein/AP endonuclease YP_001491773.1 40067 R 293613 CDS YP_001491774.1 157803225 5626747 complement(41107..42300) 1 NC_009879.1 COG1398 Fatty-acid desaturase; O-sialoglycoprotein endopeptidase 42300 5626747 A1E_00180 Rickettsia canadensis str. McKiel O-sialoglycoprotein endopeptidase YP_001491774.1 41107 R 293613 CDS YP_001491775.1 157803226 5625945 43248..43613 1 NC_009879.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 43613 rpsF 5625945 rpsF Rickettsia canadensis str. McKiel 30S ribosomal protein S6 YP_001491775.1 43248 D 293613 CDS YP_001491776.1 157803227 5625946 43638..43925 1 NC_009879.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 43925 rpsR 5625946 rpsR Rickettsia canadensis str. McKiel 30S ribosomal protein S18 YP_001491776.1 43638 D 293613 CDS YP_001491777.1 157803228 5625947 43937..44452 1 NC_009879.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 44452 rplI 5625947 rplI Rickettsia canadensis str. McKiel 50S ribosomal protein L9 YP_001491777.1 43937 D 293613 CDS YP_001491778.1 157803229 5625948 44961..46259 1 NC_009879.1 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile)-lysidine synthetase TilS 46259 5625948 A1E_00200 Rickettsia canadensis str. McKiel tRNA(Ile)-lysidine synthetase TilS YP_001491778.1 44961 D 293613 CDS YP_001491779.1 157803230 5625949 46356..48266 1 NC_009879.1 COG0465 ATP-dependent Zn proteases; 50S ribosomal protein L9 48266 rplI 5625949 rplI Rickettsia canadensis str. McKiel 50S ribosomal protein L9 YP_001491779.1 46356 D 293613 CDS YP_001491780.1 157803231 5626180 48267..49052 1 NC_009879.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 49052 sdhB 5626180 sdhB Rickettsia canadensis str. McKiel succinate dehydrogenase iron-sulfur subunit YP_001491780.1 48267 D 293613 CDS YP_001491781.1 157803232 5626181 complement(50050..51126) 1 NC_009879.1 COG1565 Uncharacterized conserved protein; succinate dehydrogenase iron-sulfur subunit 51126 sdhB 5626181 sdhB Rickettsia canadensis str. McKiel succinate dehydrogenase iron-sulfur subunit YP_001491781.1 50050 R 293613 CDS YP_001491782.1 157803233 5626182 complement(51105..51884) 1 NC_009879.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 51884 5626182 A1E_00220 Rickettsia canadensis str. McKiel prolipoprotein diacylglyceryl transferase YP_001491782.1 51105 R 293613 CDS YP_001491783.1 157803234 5626183 52158..53309 1 NC_009879.1 COG0668 Small-conductance mechanosensitive channel; putative carbamate kinase 53309 5626183 A1E_00225 Rickettsia canadensis str. McKiel putative carbamate kinase YP_001491783.1 52158 D 293613 CDS YP_001491784.1 157803235 5626184 53499..55181 1 NC_009879.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 55181 5626184 A1E_00230 Rickettsia canadensis str. McKiel putative inner membrane protein translocase component YidC YP_001491784.1 53499 D 293613 CDS YP_001491785.1 157803236 5626354 55181..55726 1 NC_009879.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 55726 5626354 A1E_00235 Rickettsia canadensis str. McKiel CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001491785.1 55181 D 293613 CDS YP_001491786.1 157803237 5626355 56122..56274 1 NC_009879.1 hypothetical protein 56274 5626355 A1E_00240 Rickettsia canadensis str. McKiel hypothetical protein YP_001491786.1 56122 D 293613 CDS YP_001491787.1 157803238 5626356 complement(56527..56925) 1 NC_009879.1 COG0558 Phosphatidylglycerophosphate synthase; hypothetical protein 56925 5626356 A1E_00245 Rickettsia canadensis str. McKiel hypothetical protein YP_001491787.1 56527 R 293613 CDS YP_001491788.1 157803239 5626357 58011..59516 1 NC_009879.1 COG3202 ATP/ADP translocase; ADP,ATP carrier protein 59516 5626357 A1E_00250 Rickettsia canadensis str. McKiel ADP,ATP carrier protein YP_001491788.1 58011 D 293613 CDS YP_001491789.1 157803240 5626358 59583..60872 1 NC_009879.1 COG2271 Sugar phosphate permease; putative inner membrane protein translocase component YidC 60872 5626358 A1E_00255 Rickettsia canadensis str. McKiel putative inner membrane protein translocase component YidC YP_001491789.1 59583 D 293613 CDS YP_001491790.1 157803241 5626094 60902..61324 1 NC_009879.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 61324 ndk 5626094 ndk Rickettsia canadensis str. McKiel nucleoside diphosphate kinase YP_001491790.1 60902 D 293613 CDS YP_001491791.1 157803242 5626095 61328..63202 1 NC_009879.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 63202 5626095 A1E_00265 Rickettsia canadensis str. McKiel tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_001491791.1 61328 D 293613 CDS YP_001491792.1 157803243 5626096 63722..64489 1 NC_009879.1 COG1192 ATPases involved in chromosome partitioning; soj protein 64489 5626096 A1E_00270 Rickettsia canadensis str. McKiel soj protein YP_001491792.1 63722 D 293613 CDS YP_001491793.1 157803244 5626097 64476..65336 1 NC_009879.1 COG1475 Predicted transcriptional regulators; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 65336 5626097 A1E_00275 Rickettsia canadensis str. McKiel tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_001491793.1 64476 D 293613 CDS YP_001491794.1 157803245 5626098 65627..67294 1 NC_009879.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 67294 5626098 A1E_00280 Rickettsia canadensis str. McKiel putative ABC transporter ATP-binding protein YP_001491794.1 65627 D 293613 CDS YP_001491795.1 157803246 5626872 67297..67614 1 NC_009879.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; putative ABC transporter ATP-binding component 67614 5626872 A1E_00285 Rickettsia canadensis str. McKiel putative ABC transporter ATP-binding component YP_001491795.1 67297 D 293613 CDS YP_001491796.1 157803247 5626873 67649..68473 1 NC_009879.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 68473 5626873 A1E_00290 Rickettsia canadensis str. McKiel 2-dehydro-3-deoxyphosphooctonate aldolase YP_001491796.1 67649 D 293613 CDS YP_001491797.1 157803248 5626874 69000..69086 1 NC_009879.1 COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; hypothetical protein 69086 5626874 A1E_00295 Rickettsia canadensis str. McKiel hypothetical protein YP_001491797.1 69000 D 293613 CDS YP_001491798.1 157803249 5626875 complement(69865..70197) 1 NC_009879.1 COG0316 Uncharacterized conserved protein; 2-dehydro-3-deoxyphosphooctonate aldolase 70197 5626875 A1E_00300 Rickettsia canadensis str. McKiel 2-dehydro-3-deoxyphosphooctonate aldolase YP_001491798.1 69865 R 293613 CDS YP_001491799.1 157803250 5626876 70360..71490 1 NC_009879.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 71490 5626876 A1E_00305 Rickettsia canadensis str. McKiel deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_001491799.1 70360 D 293613 CDS YP_001491800.1 157803251 5625853 71666..73396 1 NC_009879.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 73396 argS 5625853 argS Rickettsia canadensis str. McKiel arginyl-tRNA synthetase YP_001491800.1 71666 D 293613 CDS YP_001491801.1 157803252 5625854 73472..74143 1 NC_009879.1 COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase 74143 argS 5625854 argS Rickettsia canadensis str. McKiel arginyl-tRNA synthetase YP_001491801.1 73472 D 293613 CDS YP_001491802.1 157803253 5625855 74328..76544 1 NC_009879.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 76544 5625855 A1E_00320 Rickettsia canadensis str. McKiel DNA topoisomerase IV subunit A YP_001491802.1 74328 D 293613 CDS YP_001491803.1 157803254 5625856 complement(76908..78230) 1 NC_009879.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA topoisomerase IV subunit A 78230 5625856 A1E_00325 Rickettsia canadensis str. McKiel DNA topoisomerase IV subunit A YP_001491803.1 76908 R 293613 CDS YP_001491804.1 157803255 5625857 78514..79080 1 NC_009879.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 79080 dcd 5625857 dcd Rickettsia canadensis str. McKiel deoxycytidine triphosphate deaminase YP_001491804.1 78514 D 293613 CDS YP_001491805.1 157803256 5626707 79177..79635 1 NC_009879.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 79635 5626707 A1E_00335 Rickettsia canadensis str. McKiel preprotein translocase subunit SecB YP_001491805.1 79177 D 293613 CDS YP_001491806.1 157803257 5626708 79861..80574 1 NC_009879.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; preprotein translocase subunit SecB 80574 5626708 A1E_00340 Rickettsia canadensis str. McKiel preprotein translocase subunit SecB YP_001491806.1 79861 D 293613 CDS YP_001491807.1 157803258 5626709 80578..81399 1 NC_009879.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 81399 queF 5626709 queF Rickettsia canadensis str. McKiel 7-cyano-7-deazaguanine reductase YP_001491807.1 80578 D 293613 CDS YP_001491808.1 157803259 5626710 complement(81672..82232) 1 NC_009879.1 COG3820 Uncharacterized protein conserved in bacteria; hypothetical protein 82232 5626710 A1E_00350 Rickettsia canadensis str. McKiel hypothetical protein YP_001491808.1 81672 R 293613 CDS YP_001491809.1 157803260 5626711 complement(82887..82976) 1 NC_009879.1 hypothetical protein 82976 5626711 A1E_00360 Rickettsia canadensis str. McKiel hypothetical protein YP_001491809.1 82887 R 293613 CDS YP_001491810.1 157803261 5626052 83232..83489 1 NC_009879.1 COG1282 NAD/NADP transhydrogenase beta subunit; hypothetical protein 83489 5626052 A1E_00370 Rickettsia canadensis str. McKiel hypothetical protein YP_001491810.1 83232 D 293613 CDS YP_001491811.1 157803262 5626053 complement(83991..84722) 1 NC_009879.1 COG3047 Outer membrane protein W; hypothetical protein 84722 5626053 A1E_00380 Rickettsia canadensis str. McKiel hypothetical protein YP_001491811.1 83991 R 293613 CDS YP_001491812.1 157803263 5626054 84866..85750 1 NC_009879.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; S-adenosylmethionine transporter 85750 5626054 A1E_00385 Rickettsia canadensis str. McKiel S-adenosylmethionine transporter YP_001491812.1 84866 D 293613 CDS YP_001491813.1 157803264 5626055 85737..86999 1 NC_009879.1 7-cyano-7-deazaguanine reductase 86999 queF 5626055 queF Rickettsia canadensis str. McKiel 7-cyano-7-deazaguanine reductase YP_001491813.1 85737 D 293613 CDS YP_001491814.1 157803265 5626712 87321..87623 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; preprotein translocase subunit SecG 87623 secG 5626712 secG Rickettsia canadensis str. McKiel preprotein translocase subunit SecG YP_001491814.1 87321 D 293613 CDS YP_001491815.1 157803266 5626713 87913..88575 1 NC_009879.1 hypothetical protein 88575 5626713 A1E_00400 Rickettsia canadensis str. McKiel hypothetical protein YP_001491815.1 87913 D 293613 CDS YP_001491816.1 157803267 5626714 complement(88817..94246) 1 NC_009879.1 COG1738 Uncharacterized conserved protein; preprotein translocase subunit SecG 94246 secG 5626714 secG Rickettsia canadensis str. McKiel preprotein translocase subunit SecG YP_001491816.1 88817 R 293613 CDS YP_001491817.1 157803268 5626715 94415..95794 1 NC_009879.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 95794 cysS 5626715 cysS Rickettsia canadensis str. McKiel cysteinyl-tRNA synthetase YP_001491817.1 94415 D 293613 CDS YP_001491818.1 157803269 5625831 96094..96981 1 NC_009879.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 96981 rpsB 5625831 rpsB Rickettsia canadensis str. McKiel 30S ribosomal protein S2 YP_001491818.1 96094 D 293613 CDS YP_001491819.1 157803270 5625832 97003..97932 1 NC_009879.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 97932 tsf 5625832 tsf Rickettsia canadensis str. McKiel elongation factor Ts YP_001491819.1 97003 D 293613 CDS YP_001491820.1 157803271 5625833 complement(98936..100189) 1 NC_009879.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 100189 5625833 A1E_00425 Rickettsia canadensis str. McKiel 3-deoxy-D-manno-octulosonic-acid transferase YP_001491820.1 98936 R 293613 CDS YP_001491821.1 157803272 5625834 complement(100186..100842) 1 NC_009879.1 COG2121 Uncharacterized protein conserved in bacteria; 3-deoxy-D-manno-octulosonic-acid transferase 100842 5625834 A1E_00430 Rickettsia canadensis str. McKiel 3-deoxy-D-manno-octulosonic-acid transferase YP_001491821.1 100186 R 293613 CDS YP_001491822.1 157803273 5625835 complement(100917..102137) 1 NC_009879.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 102137 5625835 A1E_00435 Rickettsia canadensis str. McKiel aspartate aminotransferase YP_001491822.1 100917 R 293613 CDS YP_001491823.1 157803274 5626508 102411..103418 1 NC_009879.1 COG0457 FOG: TPR repeat; hypothetical protein 103418 5626508 A1E_00440 Rickettsia canadensis str. McKiel hypothetical protein YP_001491823.1 102411 D 293613 CDS YP_001491824.1 157803275 5626509 103393..104178 1 NC_009879.1 COG2853 Surface lipoprotein; vacJ lipoprotein precursor 104178 5626509 A1E_00445 Rickettsia canadensis str. McKiel vacJ lipoprotein precursor YP_001491824.1 103393 D 293613 CDS YP_001491825.1 157803276 5626510 104204..104794 1 NC_009879.1 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component; aspartate aminotransferase 104794 5626510 A1E_00450 Rickettsia canadensis str. McKiel aspartate aminotransferase YP_001491825.1 104204 D 293613 CDS YP_001491826.1 157803277 5626511 105806..106873 1 NC_009879.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 106873 alr 5626511 alr Rickettsia canadensis str. McKiel alanine racemase YP_001491826.1 105806 D 293613 CDS YP_001491827.1 157803278 5626512 107108..107887 1 NC_009879.1 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; ABC transporter permease protein 107887 5626512 A1E_00460 Rickettsia canadensis str. McKiel ABC transporter permease protein YP_001491827.1 107108 D 293613 CDS YP_001491828.1 157803279 5626275 107890..108651 1 NC_009879.1 ribonucleotide ABC transporter ATP-binding protein 108651 5626275 A1E_00465 Rickettsia canadensis str. McKiel ribonucleotide ABC transporter ATP-binding protein YP_001491828.1 107890 D 293613 CDS YP_001491829.1 157803280 5626276 108694..108942 1 NC_009879.1 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; alanine racemase 108942 alr 5626276 alr Rickettsia canadensis str. McKiel alanine racemase YP_001491829.1 108694 D 293613 CDS YP_001491830.1 157803281 5626277 109015..109308 1 NC_009879.1 required for 70S ribosome assembly; 50S ribosomal protein L28 109308 rpmB 5626277 rpmB Rickettsia canadensis str. McKiel 50S ribosomal protein L28 YP_001491830.1 109015 D 293613 CDS YP_001491831.1 157803282 5626278 109305..109541 1 NC_009879.1 RpmE; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 109541 5626278 A1E_00480 Rickettsia canadensis str. McKiel 50S ribosomal protein L31 YP_001491831.1 109305 D 293613 CDS YP_001491832.1 157803283 5626628 110321..110980 1 NC_009879.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 110980 engB 5626628 engB Rickettsia canadensis str. McKiel ribosome biogenesis GTP-binding protein YsxC YP_001491832.1 110321 D 293613 CDS YP_001491833.1 157803284 5626629 111131..111256 1 NC_009879.1 COG0218 Predicted GTPase; acetylglutamate kinase 111256 5626629 A1E_00490 Rickettsia canadensis str. McKiel acetylglutamate kinase YP_001491833.1 111131 D 293613 CDS YP_001491834.1 157803285 5626630 111737..112024 1 NC_009879.1 COG3702 Type IV secretory pathway, VirB3 components; type IV secretion system protein VirB3 112024 5626630 A1E_00495 Rickettsia canadensis str. McKiel type IV secretion system protein VirB3 YP_001491834.1 111737 D 293613 CDS YP_001491835.1 157803286 5626631 112279..114696 1 NC_009879.1 COG3451 Type IV secretory pathway, VirB4 components; type IV secretion system ATPase VirB4 114696 5626631 A1E_00500 Rickettsia canadensis str. McKiel type IV secretion system ATPase VirB4 YP_001491835.1 112279 D 293613 CDS YP_001491836.1 157803287 5626035 114838..118152 1 NC_009879.1 COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 118152 5626035 A1E_00505 Rickettsia canadensis str. McKiel TrbL/VirB6 plasmid conjugative transfer protein YP_001491836.1 114838 D 293613 CDS YP_001491837.1 157803288 5626036 118139..120157 1 NC_009879.1 COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 120157 5626036 A1E_00510 Rickettsia canadensis str. McKiel TrbL/VirB6 plasmid conjugative transfer protein YP_001491837.1 118139 D 293613 CDS YP_001491838.1 157803289 5626037 120164..123070 1 NC_009879.1 COG3704 Type IV secretory pathway, VirB6 components; VirB6-like protein of the type IV secretion system 123070 5626037 A1E_00515 Rickettsia canadensis str. McKiel VirB6-like protein of the type IV secretion system YP_001491838.1 120164 D 293613 CDS YP_001491839.1 157803290 5626038 123077..125743 1 NC_009879.1 COG3704 Type IV secretory pathway, VirB6 components; hypothetical protein 125743 5626038 A1E_00520 Rickettsia canadensis str. McKiel hypothetical protein YP_001491839.1 123077 D 293613 CDS YP_001491840.1 157803291 5626039 125852..129292 1 NC_009879.1 hypothetical protein 129292 5626039 A1E_00525 Rickettsia canadensis str. McKiel hypothetical protein YP_001491840.1 125852 D 293613 CDS YP_001491841.1 157803292 5626696 130793..130897 1 NC_009879.1 GTPase EngB 130897 5626696 A1E_00540 Rickettsia canadensis str. McKiel GTPase EngB YP_001491841.1 130793 D 293613 CDS YP_001491842.1 157803293 5626697 130964..131041 1 NC_009879.1 hypothetical protein 131041 5626697 A1E_00545 Rickettsia canadensis str. McKiel hypothetical protein YP_001491842.1 130964 D 293613 CDS YP_001491843.1 157803294 5626698 132049..132165 1 NC_009879.1 hypothetical protein 132165 5626698 A1E_00550 Rickettsia canadensis str. McKiel hypothetical protein YP_001491843.1 132049 D 293613 CDS YP_001491844.1 157803295 5626699 132389..132664 1 NC_009879.1 COG0280 Phosphotransacetylase; hypothetical protein 132664 5626699 A1E_00555 Rickettsia canadensis str. McKiel hypothetical protein YP_001491844.1 132389 D 293613 CDS YP_001491845.1 157803296 5626700 132753..133415 1 NC_009879.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 133415 trmD 5626700 trmD Rickettsia canadensis str. McKiel tRNA (guanine-N(1)-)-methyltransferase YP_001491845.1 132753 D 293613 CDS YP_001491846.1 157803297 5626390 133672..134088 1 NC_009879.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 134088 rplS 5626390 rplS Rickettsia canadensis str. McKiel 50S ribosomal protein L19 YP_001491846.1 133672 D 293613 CDS YP_001491847.1 157803298 5626391 complement(134364..134600) 1 NC_009879.1 COG3750 Uncharacterized protein conserved in bacteria; hypothetical protein 134600 rplS 5626391 rplS Rickettsia canadensis str. McKiel hypothetical protein YP_001491847.1 134364 R 293613 CDS YP_001491848.1 157803299 5626392 134672..135604 1 NC_009879.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 135604 secF 5626392 secF Rickettsia canadensis str. McKiel preprotein translocase subunit SecF YP_001491848.1 134672 D 293613 CDS YP_001491849.1 157803300 5626393 135718..136980 1 NC_009879.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 136980 5626393 A1E_00580 Rickettsia canadensis str. McKiel NADH dehydrogenase I subunit F YP_001491849.1 135718 D 293613 CDS YP_001491850.1 157803301 5626394 137144..137941 1 NC_009879.1 COG0681 Signal peptidase I; preprotein translocase subunit SecF 137941 secF 5626394 secF Rickettsia canadensis str. McKiel preprotein translocase subunit SecF YP_001491850.1 137144 D 293613 CDS YP_001491851.1 157803302 5625998 137941..138624 1 NC_009879.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 138624 rnc 5625998 rnc Rickettsia canadensis str. McKiel ribonuclease III YP_001491851.1 137941 D 293613 CDS YP_001491852.1 157803303 5625999 138617..139504 1 NC_009879.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 139504 era 5625999 era Rickettsia canadensis str. McKiel GTP-binding protein Era YP_001491852.1 138617 D 293613 CDS YP_001491853.1 157803304 5626000 139628..140170 1 NC_009879.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 140170 ruvC 5626000 ruvC Rickettsia canadensis str. McKiel Holliday junction resolvase YP_001491853.1 139628 D 293613 CDS YP_001491854.1 157803305 5626001 140172..140864 1 NC_009879.1 COG0565 rRNA methylase; tRNA/rRNA methyltransferase 140864 5626001 A1E_00605 Rickettsia canadensis str. McKiel tRNA/rRNA methyltransferase YP_001491854.1 140172 D 293613 CDS YP_001491855.1 157803306 5626002 complement(141014..142102) 1 NC_009879.1 COG3660 Predicted nucleoside-diphosphate-sugar epimerase; hypothetical protein 142102 5626002 A1E_00610 Rickettsia canadensis str. McKiel hypothetical protein YP_001491855.1 141014 R 293613 CDS YP_001491856.1 157803307 5625809 complement(142099..143205) 1 NC_009879.1 COG0489 ATPases involved in chromosome partitioning; Mrp protein 143205 5625809 A1E_00615 Rickettsia canadensis str. McKiel Mrp protein YP_001491856.1 142099 R 293613 CDS YP_001491857.1 157803308 5625810 143306..144346 1 NC_009879.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; protease activity modulator HflK 144346 5625810 A1E_00620 Rickettsia canadensis str. McKiel protease activity modulator HflK YP_001491857.1 143306 D 293613 CDS YP_001491858.1 157803309 5625811 144517..145377 1 NC_009879.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hflc protein (hflc) 145377 5625811 A1E_00625 Rickettsia canadensis str. McKiel hflc protein (hflc) YP_001491858.1 144517 D 293613 CDS YP_001491859.1 157803310 5625812 145398..146933 1 NC_009879.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Holliday junction resolvase 146933 ruvC 5625812 ruvC Rickettsia canadensis str. McKiel Holliday junction resolvase YP_001491859.1 145398 D 293613 CDS YP_001491860.1 157803311 5625813 147028..147777 1 NC_009879.1 COG1054 Predicted sulfurtransferase; hypothetical protein 147777 5625813 A1E_00635 Rickettsia canadensis str. McKiel hypothetical protein YP_001491860.1 147028 D 293613 CDS YP_001491861.1 157803312 5626197 147799..148173 1 NC_009879.1 succinate dehydrogenase cytochrome b-556 subunit 148173 5626197 A1E_00640 Rickettsia canadensis str. McKiel succinate dehydrogenase cytochrome b-556 subunit YP_001491861.1 147799 D 293613 CDS YP_001491862.1 157803313 5626198 148506..148625 1 NC_009879.1 COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; hypothetical protein 148625 5626198 A1E_00645 Rickettsia canadensis str. McKiel hypothetical protein YP_001491862.1 148506 D 293613 CDS YP_001491863.1 157803314 5626199 149004..149381 1 NC_009879.1 COG2142 Succinate dehydrogenase, hydrophobic anchor subunit; hypothetical protein 149381 5626199 A1E_00650 Rickettsia canadensis str. McKiel hypothetical protein YP_001491863.1 149004 D 293613 CDS YP_001491864.1 157803315 5626200 149579..151369 1 NC_009879.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 151369 sdhA 5626200 sdhA Rickettsia canadensis str. McKiel succinate dehydrogenase flavoprotein subunit YP_001491864.1 149579 D 293613 CDS YP_001491865.1 157803316 5626201 complement(151411..151509) 1 NC_009879.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; hypothetical protein 151509 5626201 A1E_00660 Rickettsia canadensis str. McKiel hypothetical protein YP_001491865.1 151411 R 293613 CDS YP_001491866.1 157803317 5626291 151578..152234 1 NC_009879.1 COG0765 ABC-type amino acid transport system, permease component; succinate dehydrogenase flavoprotein subunit 152234 sdhA 5626291 sdhA Rickettsia canadensis str. McKiel succinate dehydrogenase flavoprotein subunit YP_001491866.1 151578 D 293613 CDS YP_001491867.1 157803318 5626292 152392..152781 1 NC_009879.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 152781 rpsL 5626292 rpsL Rickettsia canadensis str. McKiel 30S ribosomal protein S12 YP_001491867.1 152392 D 293613 CDS YP_001491868.1 157803319 5626293 152809..153291 1 NC_009879.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 153291 5626293 A1E_00675 Rickettsia canadensis str. McKiel 30S ribosomal protein S7 YP_001491868.1 152809 D 293613 CDS YP_001491869.1 157803320 5626294 153304..155376 1 NC_009879.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 155376 5626294 A1E_00680 Rickettsia canadensis str. McKiel elongation factor G YP_001491869.1 153304 D 293613 CDS YP_001491870.1 157803321 5626381 155746..156009 1 NC_009879.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 156009 secE 5626381 secE Rickettsia canadensis str. McKiel preprotein translocase subunit SecE YP_001491870.1 155746 D 293613 CDS YP_001491871.1 157803322 5626382 156025..156603 1 NC_009879.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 156603 nusG 5626382 nusG Rickettsia canadensis str. McKiel transcription antitermination protein NusG YP_001491871.1 156025 D 293613 CDS YP_001491872.1 157803323 5626383 156835..157272 1 NC_009879.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 157272 rplK 5626383 rplK Rickettsia canadensis str. McKiel 50S ribosomal protein L11 YP_001491872.1 156835 D 293613 CDS YP_001491873.1 157803324 5626384 157278..157997 1 NC_009879.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 157997 rplA 5626384 rplA Rickettsia canadensis str. McKiel 50S ribosomal protein L1 YP_001491873.1 157278 D 293613 CDS YP_001491874.1 157803325 5626567 158282..158791 1 NC_009879.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 158791 rplJ 5626567 rplJ Rickettsia canadensis str. McKiel 50S ribosomal protein L10 YP_001491874.1 158282 D 293613 CDS YP_001491875.1 157803326 5626568 158823..159200 1 NC_009879.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 159200 rplL 5626568 rplL Rickettsia canadensis str. McKiel 50S ribosomal protein L7/L12 YP_001491875.1 158823 D 293613 CDS YP_001491876.1 157803327 5626569 159903..164024 1 NC_009879.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 164024 rpoB 5626569 rpoB Rickettsia canadensis str. McKiel DNA-directed RNA polymerase subunit beta YP_001491876.1 159903 D 293613 CDS YP_001491877.1 157803328 5626570 164217..168353 1 NC_009879.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 168353 5626570 A1E_00720 Rickettsia canadensis str. McKiel DNA-directed RNA polymerase subunit beta' YP_001491877.1 164217 D 293613 CDS YP_001491878.1 157803329 5626571 complement(168570..169487) 1 NC_009879.1 COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' 169487 5626571 A1E_00725 Rickettsia canadensis str. McKiel DNA-directed RNA polymerase subunit beta' YP_001491878.1 168570 R 293613 CDS YP_001491879.1 157803330 5626691 169864..171366 1 NC_009879.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 171366 5626691 A1E_00730 Rickettsia canadensis str. McKiel leucyl aminopeptidase YP_001491879.1 169864 D 293613 CDS YP_001491880.1 157803331 5626692 171560..172354 1 NC_009879.1 hypothetical protein 172354 5626692 A1E_00735 Rickettsia canadensis str. McKiel hypothetical protein YP_001491880.1 171560 D 293613 CDS YP_001491881.1 157803332 5626693 172435..172866 1 NC_009879.1 COG1192 ATPases involved in chromosome partitioning; leucyl aminopeptidase 172866 5626693 A1E_00740 Rickettsia canadensis str. McKiel leucyl aminopeptidase YP_001491881.1 172435 D 293613 CDS YP_001491882.1 157803333 5626694 172942..174750 1 NC_009879.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 174750 aspS 5626694 aspS Rickettsia canadensis str. McKiel aspartyl-tRNA synthetase YP_001491882.1 172942 D 293613 CDS YP_001491883.1 157803334 5626695 complement(175182..175892) 1 NC_009879.1 COG0670 Integral membrane protein, interacts with FtsH; aspartyl-tRNA synthetase 175892 aspS 5626695 aspS Rickettsia canadensis str. McKiel aspartyl-tRNA synthetase YP_001491883.1 175182 R 293613 CDS YP_001491884.1 157803335 5625826 complement(175958..176680) 1 NC_009879.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 176680 5625826 A1E_00755 Rickettsia canadensis str. McKiel dihydrodipicolinate reductase YP_001491884.1 175958 R 293613 CDS YP_001491885.1 157803336 5625827 complement(176688..177170) 1 NC_009879.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein 177170 5625827 A1E_00760 Rickettsia canadensis str. McKiel hypothetical protein YP_001491885.1 176688 R 293613 CDS YP_001491886.1 157803337 5625828 complement(177155..177880) 1 NC_009879.1 dihydrodipicolinate reductase 177880 5625828 A1E_00765 Rickettsia canadensis str. McKiel dihydrodipicolinate reductase YP_001491886.1 177155 R 293613 CDS YP_001491887.1 157803338 5625829 complement(177877..177960) 1 NC_009879.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; hypothetical protein 177960 5625829 A1E_00770 Rickettsia canadensis str. McKiel hypothetical protein YP_001491887.1 177877 R 293613 CDS YP_001491888.1 157803339 5625830 complement(177960..179411) 1 NC_009879.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 179411 gatB 5625830 gatB Rickettsia canadensis str. McKiel aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001491888.1 177960 R 293613 CDS YP_001491889.1 157803340 5626492 complement(179414..180895) 1 NC_009879.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 180895 gatA 5626492 gatA Rickettsia canadensis str. McKiel aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001491889.1 179414 R 293613 CDS YP_001491890.1 157803341 5626493 complement(180898..181200) 1 NC_009879.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 181200 gatC 5626493 gatC Rickettsia canadensis str. McKiel aspartyl/glutamyl-tRNA amidotransferase subunit C YP_001491890.1 180898 R 293613 CDS YP_001491891.1 157803342 5626494 complement(181370..181930) 1 NC_009879.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 181930 frr 5626494 frr Rickettsia canadensis str. McKiel ribosome recycling factor YP_001491891.1 181370 R 293613 CDS YP_001491892.1 157803343 5626495 complement(181934..182662) 1 NC_009879.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 182662 pyrH 5626495 pyrH Rickettsia canadensis str. McKiel uridylate kinase YP_001491892.1 181934 R 293613 CDS YP_001491893.1 157803344 5626496 complement(182659..182991) 1 NC_009879.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E 182991 5626496 A1E_00800 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit E YP_001491893.1 182659 R 293613 CDS YP_001491894.1 157803345 5626766 complement(182975..184537) 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein B 184537 5626766 A1E_00805 Rickettsia canadensis str. McKiel multidrug resistance protein B YP_001491894.1 182975 R 293613 CDS YP_001491895.1 157803346 5626767 184863..185066 1 NC_009879.1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; hypothetical protein 185066 5626767 A1E_00810 Rickettsia canadensis str. McKiel hypothetical protein YP_001491895.1 184863 D 293613 CDS YP_001491896.1 157803347 5626769 complement(185970..188276) 1 NC_009879.1 COG4775 Outer membrane protein/protective antigen OMA87; Outer membrane protein omp1 188276 5626769 A1E_00815 Rickettsia canadensis str. McKiel Outer membrane protein omp1 YP_001491896.1 185970 R 293613 CDS YP_001491897.1 157803348 5626900 complement(188580..189656) 1 NC_009879.1 COG0750 Predicted membrane-associated Zn-dependent proteases 1; putative monovalent cation/H+ antiporter subunit E 189656 5626900 A1E_00820 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit E YP_001491897.1 188580 R 293613 CDS YP_001491898.1 157803349 5626901 189855..190391 1 NC_009879.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 190391 nusB 5626901 nusB Rickettsia canadensis str. McKiel transcription antitermination protein NusB YP_001491898.1 189855 D 293613 CDS YP_001491899.1 157803350 5626902 190388..191071 1 NC_009879.1 ribosomal RNA large subunit methyltransferase J 191071 5626902 A1E_00830 Rickettsia canadensis str. McKiel ribosomal RNA large subunit methyltransferase J YP_001491899.1 190388 D 293613 CDS YP_001491900.1 157803351 5626903 complement(191118..191339) 1 NC_009879.1 hypothetical protein 191339 5626903 A1E_00835 Rickettsia canadensis str. McKiel hypothetical protein YP_001491900.1 191118 R 293613 CDS YP_001491901.1 157803352 5626904 complement(191333..192448) 1 NC_009879.1 COG0293 23S rRNA methylase; hypothetical protein 192448 5626904 A1E_00840 Rickettsia canadensis str. McKiel hypothetical protein YP_001491901.1 191333 R 293613 CDS YP_001491902.1 157803353 5626618 complement(193122..193562) 1 NC_009879.1 COG2867 Oligoketide cyclase/lipid transport protein; transcription antitermination protein NusB 193562 nusB 5626618 nusB Rickettsia canadensis str. McKiel transcription antitermination protein NusB YP_001491902.1 193122 R 293613 CDS YP_001491903.1 157803354 5626619 complement(194099..194923) 1 NC_009879.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 194923 dapD 5626619 dapD Rickettsia canadensis str. McKiel 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001491903.1 194099 R 293613 CDS YP_001491904.1 157803355 5626620 195003..195623 1 NC_009879.1 hypothetical protein 195623 5626620 A1E_00855 Rickettsia canadensis str. McKiel hypothetical protein YP_001491904.1 195003 D 293613 CDS YP_001491905.1 157803356 5626621 complement(195946..196302) 1 NC_009879.1 COG2171 Tetrahydrodipicolinate N-succinyltransferase; hypothetical protein 196302 5626621 A1E_00860 Rickettsia canadensis str. McKiel hypothetical protein YP_001491905.1 195946 R 293613 CDS YP_001491906.1 157803357 5626622 complement(196452..197303) 1 NC_009879.1 COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; cytochrome c oxidase subunit III 197303 5626622 A1E_00865 Rickettsia canadensis str. McKiel cytochrome c oxidase subunit III YP_001491906.1 196452 R 293613 CDS YP_001491907.1 157803358 5626727 complement(197901..198440) 1 NC_009879.1 COG2941 Ubiquinone biosynthesis protein COQ7; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase 198440 dapD 5626727 dapD Rickettsia canadensis str. McKiel 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase YP_001491907.1 197901 R 293613 CDS YP_001491908.1 157803359 5626728 complement(198589..199560) 1 NC_009879.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 199560 holA 5626728 holA Rickettsia canadensis str. McKiel DNA polymerase III subunit delta YP_001491908.1 198589 R 293613 CDS YP_001491909.1 157803360 5626729 complement(199727..200197) 1 NC_009879.1 hypothetical protein 200197 5626729 A1E_00880 Rickettsia canadensis str. McKiel hypothetical protein YP_001491909.1 199727 R 293613 CDS YP_001491910.1 157803361 5626730 200419..200691 1 NC_009879.1 hypothetical protein 200691 5626730 A1E_00885 Rickettsia canadensis str. McKiel hypothetical protein YP_001491910.1 200419 D 293613 CDS YP_001491911.1 157803362 5626731 complement(200877..200969) 1 NC_009879.1 COG1466 DNA polymerase III, delta subunit; hypothetical protein 200969 5626731 A1E_00890 Rickettsia canadensis str. McKiel hypothetical protein YP_001491911.1 200877 R 293613 CDS YP_001491912.1 157803363 5626433 complement(201646..203139) 1 NC_009879.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; DNA polymerase III subunit delta 203139 holA 5626433 holA Rickettsia canadensis str. McKiel DNA polymerase III subunit delta YP_001491912.1 201646 R 293613 CDS YP_001491913.1 157803364 5626434 203206..205089 1 NC_009879.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 205089 dnaK 5626434 dnaK Rickettsia canadensis str. McKiel molecular chaperone DnaK YP_001491913.1 203206 D 293613 CDS YP_001491914.1 157803365 5626435 205199..206326 1 NC_009879.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 206326 5626435 A1E_00905 Rickettsia canadensis str. McKiel chaperone protein DnaJ YP_001491914.1 205199 D 293613 CDS YP_001491915.1 157803366 5626436 206461..206649 1 NC_009879.1 COG4572 Putative cation transport regulator; hypothetical protein 206649 5626436 A1E_00910 Rickettsia canadensis str. McKiel hypothetical protein YP_001491915.1 206461 D 293613 CDS YP_001491916.1 157803367 5626437 206730..207473 1 NC_009879.1 COG4105 DNA uptake lipoprotein; hypothetical protein 207473 5626437 A1E_00915 Rickettsia canadensis str. McKiel hypothetical protein YP_001491916.1 206730 D 293613 CDS YP_001491917.1 157803368 5626364 207631..209271 1 NC_009879.1 COG0497 ATPase involved in DNA repair; DNA repair protein RecN 209271 5626364 A1E_00920 Rickettsia canadensis str. McKiel DNA repair protein RecN YP_001491917.1 207631 D 293613 CDS YP_001491918.1 157803369 5626365 209552..210946 1 NC_009879.1 COG2317 Zn-dependent carboxypeptidase; molecular chaperone DnaK 210946 dnaK 5626365 dnaK Rickettsia canadensis str. McKiel molecular chaperone DnaK YP_001491918.1 209552 D 293613 CDS YP_001491919.1 157803370 5626366 211183..213972 1 NC_009879.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 213972 sucA 5626366 sucA Rickettsia canadensis str. McKiel 2-oxoglutarate dehydrogenase E1 component YP_001491919.1 211183 D 293613 CDS YP_001491920.1 157803371 5626367 214141..215346 1 NC_009879.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 215346 5626367 A1E_00935 Rickettsia canadensis str. McKiel dihydrolipoamide succinyltransferase YP_001491920.1 214141 D 293613 CDS YP_001491921.1 157803372 5626368 215505..215921 1 NC_009879.1 COG0720 6-pyruvoyl-tetrahydropterin synthase; hypothetical protein 215921 5626368 A1E_00940 Rickettsia canadensis str. McKiel hypothetical protein YP_001491921.1 215505 D 293613 CDS YP_001491922.1 157803373 5626648 215924..216388 1 NC_009879.1 COG1324 Uncharacterized protein involved in tolerance to divalent cations; periplasmic divalent cation tolerance protein 216388 5626648 A1E_00945 Rickettsia canadensis str. McKiel periplasmic divalent cation tolerance protein YP_001491922.1 215924 D 293613 CDS YP_001491923.1 157803374 5626649 216429..217628 1 NC_009879.1 proton/sodium-glutamate symport protein 217628 5626649 A1E_00950 Rickettsia canadensis str. McKiel proton/sodium-glutamate symport protein YP_001491923.1 216429 D 293613 CDS YP_001491924.1 157803375 5626650 217966..218178 1 NC_009879.1 dihydrolipoamide acetyltransferase 218178 5626650 A1E_00955 Rickettsia canadensis str. McKiel dihydrolipoamide acetyltransferase YP_001491924.1 217966 D 293613 CDS YP_001491925.1 157803376 5626651 complement(219739..219831) 1 NC_009879.1 COG1301 Na+/H+-dicarboxylate symporters; hypothetical protein 219831 5626651 A1E_00960 Rickettsia canadensis str. McKiel hypothetical protein YP_001491925.1 219739 R 293613 CDS YP_001491926.1 157803377 5626652 complement(220076..221236) 1 NC_009879.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 221236 5626652 A1E_00965 Rickettsia canadensis str. McKiel coproporphyrinogen III oxidase YP_001491926.1 220076 R 293613 CDS YP_001491927.1 157803378 5626643 complement(221532..221672) 1 NC_009879.1 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; transposase 221672 5626643 A1E_00970 Rickettsia canadensis str. McKiel transposase YP_001491927.1 221532 R 293613 CDS YP_001491928.1 157803379 5626644 complement(222056..223405) 1 NC_009879.1 COG0541 Signal recognition particle GTPase; coproporphyrinogen III oxidase 223405 5626644 A1E_00975 Rickettsia canadensis str. McKiel coproporphyrinogen III oxidase YP_001491928.1 222056 R 293613 CDS YP_001491929.1 157803380 5626645 complement(223601..224395) 1 NC_009879.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 224395 5626645 A1E_00980 Rickettsia canadensis str. McKiel DNA polymerase III subunit delta' YP_001491929.1 223601 R 293613 CDS YP_001491930.1 157803381 5626646 complement(224693..225025) 1 NC_009879.1 COG0776 Bacterial nucleoid DNA-binding protein; DNA-binding protein HU 225025 5626646 A1E_00985 Rickettsia canadensis str. McKiel DNA-binding protein HU YP_001491930.1 224693 R 293613 CDS YP_001491931.1 157803382 5626647 225535..228561 1 NC_009879.1 COG0841 Cation/multidrug efflux pump; hydrophobe/amphiphile efflux-1 HAE1 family protein 228561 5626647 A1E_00990 Rickettsia canadensis str. McKiel hydrophobe/amphiphile efflux-1 HAE1 family protein YP_001491931.1 225535 D 293613 CDS YP_001491932.1 157803383 5626438 228648..228857 1 NC_009879.1 COG2155 Uncharacterized conserved protein; hypothetical protein 228857 5626438 A1E_00995 Rickettsia canadensis str. McKiel hypothetical protein YP_001491932.1 228648 D 293613 CDS YP_001491933.1 157803384 5626439 complement(228970..229743) 1 NC_009879.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 229743 5626439 A1E_01000 Rickettsia canadensis str. McKiel 16S ribosomal RNA methyltransferase RsmE YP_001491933.1 228970 R 293613 CDS YP_001491934.1 157803385 5626440 complement(230225..230386) 1 NC_009879.1 hypothetical protein 230386 5626440 A1E_01005 Rickettsia canadensis str. McKiel hypothetical protein YP_001491934.1 230225 R 293613 CDS YP_001491935.1 157803386 5626441 complement(230518..230709) 1 NC_009879.1 bifunctional penicillin-binding protein 1C 230709 5626441 A1E_01010 Rickettsia canadensis str. McKiel bifunctional penicillin-binding protein 1C YP_001491935.1 230518 R 293613 CDS YP_001491936.1 157803387 5626442 231923..232018 1 NC_009879.1 COG1385 Uncharacterized protein conserved in bacteria; hypothetical protein 232018 5626442 A1E_01015 Rickettsia canadensis str. McKiel hypothetical protein YP_001491936.1 231923 D 293613 CDS YP_001491937.1 157803388 5625892 complement(232940..233386) 1 NC_009879.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; hypothetical protein 233386 5625892 A1E_01020 Rickettsia canadensis str. McKiel hypothetical protein YP_001491937.1 232940 R 293613 CDS YP_001491938.1 157803389 5625893 complement(233396..234346) 1 NC_009879.1 hypothetical protein 234346 5625893 A1E_01025 Rickettsia canadensis str. McKiel hypothetical protein YP_001491938.1 233396 R 293613 CDS YP_001491939.1 157803390 5625894 complement(234351..235421) 1 NC_009879.1 COG2358 TRAP-type uncharacterized transport system, periplasmic component; hypothetical protein 235421 5625894 A1E_01030 Rickettsia canadensis str. McKiel hypothetical protein YP_001491939.1 234351 R 293613 CDS YP_001491940.1 157803391 5625895 complement(235434..235772) 1 NC_009879.1 COG0633 Ferredoxin; DNA polymerase III subunit delta' 235772 5625895 A1E_01035 Rickettsia canadensis str. McKiel DNA polymerase III subunit delta' YP_001491940.1 235434 R 293613 CDS YP_001491941.1 157803392 5625896 complement(235834..237771) 1 NC_009879.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 237771 hscA 5625896 hscA Rickettsia canadensis str. McKiel chaperone protein HscA YP_001491941.1 235834 R 293613 CDS YP_001491942.1 157803393 5626244 complement(237762..238262) 1 NC_009879.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 238262 hscB 5626244 hscB Rickettsia canadensis str. McKiel co-chaperone HscB YP_001491942.1 237762 R 293613 CDS YP_001491943.1 157803394 5626245 238535..239125 1 NC_009879.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 239125 rnhB 5626245 rnhB Rickettsia canadensis str. McKiel ribonuclease HII YP_001491943.1 238535 D 293613 CDS YP_001491944.1 157803395 5626246 complement(239262..241247) 1 NC_009879.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 241247 5626246 A1E_01055 Rickettsia canadensis str. McKiel excinuclease ABC subunit B YP_001491944.1 239262 R 293613 CDS YP_001491945.1 157803396 5626247 241318..241629 1 NC_009879.1 COG0695 Glutaredoxin and related proteins; glutaredoxin, GrxC family protein 241629 5626247 A1E_01060 Rickettsia canadensis str. McKiel glutaredoxin, GrxC family protein YP_001491945.1 241318 D 293613 CDS YP_001491946.1 157803397 5626248 243888..243989 1 NC_009879.1 hypothetical protein 243989 5626248 A1E_01080 Rickettsia canadensis str. McKiel hypothetical protein YP_001491946.1 243888 D 293613 CDS YP_001491947.1 157803398 5625836 244036..244212 1 NC_009879.1 hypothetical protein 244212 5625836 A1E_01085 Rickettsia canadensis str. McKiel hypothetical protein YP_001491947.1 244036 D 293613 CDS YP_001491948.1 157803399 5625837 244206..244334 1 NC_009879.1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components; hypothetical protein 244334 5625837 A1E_01090 Rickettsia canadensis str. McKiel hypothetical protein YP_001491948.1 244206 D 293613 CDS YP_001491949.1 157803400 5625838 complement(245722..248340) 1 NC_009879.1 COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); ATP-dependent helicase 248340 5625838 A1E_01095 Rickettsia canadensis str. McKiel ATP-dependent helicase YP_001491949.1 245722 R 293613 CDS YP_001491950.1 157803401 5625839 complement(248521..249222) 1 NC_009879.1 COG3346 Uncharacterized conserved protein; excinuclease ABC subunit B 249222 5625839 A1E_01100 Rickettsia canadensis str. McKiel excinuclease ABC subunit B YP_001491950.1 248521 R 293613 CDS YP_001491951.1 157803402 5625840 complement(249422..250111) 1 NC_009879.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 250111 5625840 A1E_01105 Rickettsia canadensis str. McKiel DNA polymerase III subunit epsilon YP_001491951.1 249422 R 293613 CDS YP_001491952.1 157803403 5625955 complement(250099..250674) 1 NC_009879.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 250674 coaE 5625955 coaE Rickettsia canadensis str. McKiel dephospho-CoA kinase YP_001491952.1 250099 R 293613 CDS YP_001491953.1 157803404 5625956 complement(250668..251480) 1 NC_009879.1 COG3494 Uncharacterized protein conserved in bacteria; hypothetical protein 251480 5625956 A1E_01115 Rickettsia canadensis str. McKiel hypothetical protein YP_001491953.1 250668 R 293613 CDS YP_001491954.1 157803405 5625957 252225..252704 1 NC_009879.1 COG3814 Uncharacterized protein conserved in bacteria; dephospho-CoA kinase 252704 coaE 5625957 coaE Rickettsia canadensis str. McKiel dephospho-CoA kinase YP_001491954.1 252225 D 293613 CDS YP_001491955.1 157803406 5625958 252709..253176 1 NC_009879.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 253176 rnhA 5625958 rnhA Rickettsia canadensis str. McKiel ribonuclease H YP_001491955.1 252709 D 293613 CDS YP_001491956.1 157803407 5625959 253164..253607 1 NC_009879.1 COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit; hypothetical protein 253607 5625959 A1E_01130 Rickettsia canadensis str. McKiel hypothetical protein YP_001491956.1 253164 D 293613 CDS YP_001491957.1 157803408 5625793 253629..254081 1 NC_009879.1 ABC transporter substrate binding protein 254081 5625793 A1E_01135 Rickettsia canadensis str. McKiel ABC transporter substrate binding protein YP_001491957.1 253629 D 293613 CDS YP_001491958.1 157803409 5625794 complement(254695..254877) 1 NC_009879.1 hypothetical protein 254877 5625794 A1E_01140 Rickettsia canadensis str. McKiel hypothetical protein YP_001491958.1 254695 R 293613 CDS YP_001491959.1 157803410 5625795 255361..255621 1 NC_009879.1 hypothetical protein 255621 5625795 A1E_01145 Rickettsia canadensis str. McKiel hypothetical protein YP_001491959.1 255361 D 293613 CDS YP_001491961.1 157803412 5625797 complement(257257..257397) 1 NC_009879.1 hypothetical protein 257397 5625797 A1E_01155 Rickettsia canadensis str. McKiel hypothetical protein YP_001491961.1 257257 R 293613 CDS YP_001491962.1 157803413 5626563 258853..259002 1 NC_009879.1 hypothetical protein 259002 5626563 A1E_01160 Rickettsia canadensis str. McKiel hypothetical protein YP_001491962.1 258853 D 293613 CDS YP_001491963.1 157803414 5626565 complement(259271..259483) 1 NC_009879.1 hypothetical protein 259483 5626565 A1E_01165 Rickettsia canadensis str. McKiel hypothetical protein YP_001491963.1 259271 R 293613 CDS YP_001491964.1 157803415 5626566 complement(260074..260217) 1 NC_009879.1 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; hypothetical protein 260217 5626566 A1E_01170 Rickettsia canadensis str. McKiel hypothetical protein YP_001491964.1 260074 R 293613 CDS YP_001491965.1 157803416 5626169 complement(260563..261450) 1 NC_009879.1 hypothetical protein 261450 5626169 A1E_01175 Rickettsia canadensis str. McKiel hypothetical protein YP_001491965.1 260563 R 293613 CDS YP_001491966.1 157803417 5626170 261693..261899 1 NC_009879.1 COG0331 (acyl-carrier-protein) S-malonyltransferase; hypothetical protein 261899 5626170 A1E_01180 Rickettsia canadensis str. McKiel hypothetical protein YP_001491966.1 261693 D 293613 CDS YP_001491967.1 157803418 5626171 263214..265898 1 NC_009879.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 265898 5626171 A1E_01185 Rickettsia canadensis str. McKiel DNA gyrase subunit A YP_001491967.1 263214 D 293613 CDS YP_001491968.1 157803419 5626172 266245..266418 1 NC_009879.1 hypothetical protein 266418 5626172 A1E_01190 Rickettsia canadensis str. McKiel hypothetical protein YP_001491968.1 266245 D 293613 CDS YP_001491969.1 157803420 5626173 complement(266693..266797) 1 NC_009879.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein 266797 5626173 A1E_01195 Rickettsia canadensis str. McKiel hypothetical protein YP_001491969.1 266693 R 293613 CDS YP_001491970.1 157803421 5626146 266962..267489 1 NC_009879.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 267489 def 5626146 def Rickettsia canadensis str. McKiel peptide deformylase YP_001491970.1 266962 D 293613 CDS YP_001491971.1 157803422 5626147 267486..268397 1 NC_009879.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 268397 fmt 5626147 fmt Rickettsia canadensis str. McKiel methionyl-tRNA formyltransferase YP_001491971.1 267486 D 293613 CDS YP_001491972.1 157803423 5626148 268733..268897 1 NC_009879.1 COG0223 Methionyl-tRNA formyltransferase; hypothetical protein 268897 5626148 A1E_01210 Rickettsia canadensis str. McKiel hypothetical protein YP_001491972.1 268733 D 293613 CDS YP_001491973.1 157803424 5626150 complement(273032..274213) 1 NC_009879.1 COG1485 Predicted ATPase; methionyl-tRNA formyltransferase 274213 fmt 5626150 fmt Rickettsia canadensis str. McKiel methionyl-tRNA formyltransferase YP_001491973.1 273032 R 293613 CDS YP_001491974.1 157803425 5626359 complement(274733..275893) 1 NC_009879.1 COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine:tRNA ribosyltransferase-isomerase 275893 5626359 A1E_01220 Rickettsia canadensis str. McKiel S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_001491974.1 274733 R 293613 CDS YP_001491975.1 157803426 5626360 complement(276529..278298) 1 NC_009879.1 multidrug ABC transporter ATP-binding protein 278298 5626360 A1E_01225 Rickettsia canadensis str. McKiel multidrug ABC transporter ATP-binding protein YP_001491975.1 276529 R 293613 CDS YP_001491976.1 157803427 5626361 278483..278755 1 NC_009879.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; hypothetical protein 278755 5626361 A1E_01230 Rickettsia canadensis str. McKiel hypothetical protein YP_001491976.1 278483 D 293613 CDS YP_001491977.1 157803428 5626362 278927..280291 1 NC_009879.1 COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome d ubiquinol oxidase subunit I 280291 5626362 A1E_01235 Rickettsia canadensis str. McKiel cytochrome d ubiquinol oxidase subunit I YP_001491977.1 278927 D 293613 CDS YP_001491978.1 157803429 5626363 280975..281994 1 NC_009879.1 COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome d ubiquinol oxidase subunit II 281994 5626363 A1E_01240 Rickettsia canadensis str. McKiel cytochrome d ubiquinol oxidase subunit II YP_001491978.1 280975 D 293613 CDS YP_001491979.1 157803430 5626664 282300..283106 1 NC_009879.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; Beta 1,4 glucosyltransferase 283106 5626664 A1E_01245 Rickettsia canadensis str. McKiel Beta 1,4 glucosyltransferase YP_001491979.1 282300 D 293613 CDS YP_001491980.1 157803431 5626665 283084..284325 1 NC_009879.1 COG0612 Predicted Zn-dependent peptidases; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 284325 5626665 A1E_01250 Rickettsia canadensis str. McKiel S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_001491980.1 283084 D 293613 CDS YP_001491981.1 157803432 5626666 284335..285045 1 NC_009879.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 285045 5626666 A1E_01255 Rickettsia canadensis str. McKiel phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001491981.1 284335 D 293613 CDS YP_001491982.1 157803433 5626667 285235..286830 1 NC_009879.1 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 286830 5626667 A1E_01260 Rickettsia canadensis str. McKiel phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001491982.1 285235 D 293613 CDS YP_001491983.1 157803434 5626668 287042..288949 1 NC_009879.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 288949 thrS 5626668 thrS Rickettsia canadensis str. McKiel threonyl-tRNA synthetase YP_001491983.1 287042 D 293613 CDS YP_001491984.1 157803435 5626669 289923..290054 1 NC_009879.1 hypothetical protein 290054 5626669 A1E_01270 Rickettsia canadensis str. McKiel hypothetical protein YP_001491984.1 289923 D 293613 CDS YP_001491985.1 157803436 5626481 complement(290550..290768) 1 NC_009879.1 hypothetical protein 290768 5626481 A1E_01275 Rickettsia canadensis str. McKiel hypothetical protein YP_001491985.1 290550 R 293613 CDS YP_001491986.1 157803437 5626482 complement(291489..291902) 1 NC_009879.1 hypothetical protein 291902 5626482 A1E_01280 Rickettsia canadensis str. McKiel hypothetical protein YP_001491986.1 291489 R 293613 CDS YP_001491987.1 157803438 5626483 complement(292204..292371) 1 NC_009879.1 COG0441 Threonyl-tRNA synthetase; hypothetical protein 292371 5626483 A1E_01285 Rickettsia canadensis str. McKiel hypothetical protein YP_001491987.1 292204 R 293613 CDS YP_001491988.1 157803439 5626484 293262..293462 1 NC_009879.1 COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 293462 5626484 A1E_01290 Rickettsia canadensis str. McKiel transposase IS200-family protein YP_001491988.1 293262 D 293613 CDS YP_001491989.1 157803440 5626485 293377..293595 1 NC_009879.1 COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 293595 5626485 A1E_01295 Rickettsia canadensis str. McKiel transposase IS200-family protein YP_001491989.1 293377 D 293613 CDS YP_001491990.1 157803441 5626675 293909..295273 1 NC_009879.1 outer membrane protein tolC precursor 295273 5626675 A1E_01300 Rickettsia canadensis str. McKiel outer membrane protein tolC precursor YP_001491990.1 293909 D 293613 CDS YP_001491991.1 157803442 5626676 295305..295673 1 NC_009879.1 COG1538 Outer membrane protein; hypothetical protein 295673 5626676 A1E_01305 Rickettsia canadensis str. McKiel hypothetical protein YP_001491991.1 295305 D 293613 CDS YP_001491992.1 157803443 5626677 295853..297634 1 NC_009879.1 threonyl-tRNA synthetase 297634 thrS 5626677 thrS Rickettsia canadensis str. McKiel threonyl-tRNA synthetase YP_001491992.1 295853 D 293613 CDS YP_001491993.1 157803444 5626678 297801..299789 1 NC_009879.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 299789 5626678 A1E_01315 Rickettsia canadensis str. McKiel DNA topoisomerase IV subunit B YP_001491993.1 297801 D 293613 CDS YP_001491994.1 157803445 5626679 299958..301334 1 NC_009879.1 COG0793 Periplasmic protease; tail-specific protease precursor 301334 5626679 A1E_01320 Rickettsia canadensis str. McKiel tail-specific protease precursor YP_001491994.1 299958 D 293613 CDS YP_001491995.1 157803446 5626632 301577..303070 1 NC_009879.1 COG0642 Signal transduction histidine kinase; histidine kinase sensor protein 303070 5626632 A1E_01325 Rickettsia canadensis str. McKiel histidine kinase sensor protein YP_001491995.1 301577 D 293613 CDS YP_001491996.1 157803447 5626633 303325..304065 1 NC_009879.1 hypothetical protein 304065 5626633 A1E_01330 Rickettsia canadensis str. McKiel hypothetical protein YP_001491996.1 303325 D 293613 CDS YP_001491997.1 157803448 5626634 304078..304740 1 NC_009879.1 COG1729 Uncharacterized protein conserved in bacteria; hypothetical protein 304740 5626634 A1E_01335 Rickettsia canadensis str. McKiel hypothetical protein YP_001491997.1 304078 D 293613 CDS YP_001491998.1 157803449 5626635 304763..306007 1 NC_009879.1 COG1520 FOG: WD40-like repeat; DNA topoisomerase IV subunit B 306007 5626635 A1E_01340 Rickettsia canadensis str. McKiel DNA topoisomerase IV subunit B YP_001491998.1 304763 D 293613 CDS YP_001491999.1 157803450 5626636 306100..306576 1 NC_009879.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 306576 rplM 5626636 rplM Rickettsia canadensis str. McKiel 50S ribosomal protein L13 YP_001491999.1 306100 D 293613 CDS YP_001492000.1 157803451 5626327 306573..307058 1 NC_009879.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 307058 rpsI 5626327 rpsI Rickettsia canadensis str. McKiel 30S ribosomal protein S9 YP_001492000.1 306573 D 293613 CDS YP_001492001.1 157803452 5626329 307503..307691 1 NC_009879.1 COG2173 D-alanyl-D-alanine dipeptidase; D-alanyl-D-alanine dipeptidase 307691 5626329 A1E_01355 Rickettsia canadensis str. McKiel D-alanyl-D-alanine dipeptidase YP_001492001.1 307503 D 293613 CDS YP_001492002.1 157803453 5626330 308111..308440 1 NC_009879.1 COG2154 Pterin-4a-carbinolamine dehydratase; 30S ribosomal protein S9 308440 rpsI 5626330 rpsI Rickettsia canadensis str. McKiel 30S ribosomal protein S9 YP_001492002.1 308111 D 293613 CDS YP_001492003.1 157803454 5626732 complement(309068..309553) 1 NC_009879.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 309553 5626732 A1E_01365 Rickettsia canadensis str. McKiel dinucleoside polyphosphate hydrolase YP_001492003.1 309068 R 293613 CDS YP_001492004.1 157803455 5626733 complement(309578..310930) 1 NC_009879.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD 310930 pleD 5626733 pleD Rickettsia canadensis str. McKiel response regulator PleD YP_001492004.1 309578 R 293613 CDS YP_001492005.1 157803456 5626734 311006..311572 1 NC_009879.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 311572 5626734 A1E_01375 Rickettsia canadensis str. McKiel elongation factor P YP_001492005.1 311006 D 293613 CDS YP_001492006.1 157803457 5626735 311723..312466 1 NC_009879.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; extragenic suppressor protein SuhB 312466 5626735 A1E_01380 Rickettsia canadensis str. McKiel extragenic suppressor protein SuhB YP_001492006.1 311723 D 293613 CDS YP_001492007.1 157803458 5626736 312532..312861 1 NC_009879.1 COG0012 Predicted GTPase, probable translation factor; elongation factor P 312861 5626736 A1E_01385 Rickettsia canadensis str. McKiel elongation factor P YP_001492007.1 312532 D 293613 CDS YP_001492008.1 157803459 5626129 312893..313588 1 NC_009879.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 313588 5626129 A1E_01390 Rickettsia canadensis str. McKiel phosphatidylserine decarboxylase YP_001492008.1 312893 D 293613 CDS YP_001492009.1 157803460 5626130 313815..314588 1 NC_009879.1 COG1183 Phosphatidylserine synthase; CDP-diacylglycerol--serine O-phosphatidyltransferase 314588 5626130 A1E_01395 Rickettsia canadensis str. McKiel CDP-diacylglycerol--serine O-phosphatidyltransferase YP_001492009.1 313815 D 293613 CDS YP_001492010.1 157803461 5626131 314589..315641 1 NC_009879.1 multidrug resistance protein A 315641 5626131 A1E_01400 Rickettsia canadensis str. McKiel multidrug resistance protein A YP_001492010.1 314589 D 293613 CDS YP_001492011.1 157803462 5626132 complement(316140..316343) 1 NC_009879.1 COG1566 Multidrug resistance efflux pump; hypothetical protein 316343 5626132 A1E_01405 Rickettsia canadensis str. McKiel hypothetical protein YP_001492011.1 316140 R 293613 CDS YP_001492012.1 157803463 5626133 complement(316343..316585) 1 NC_009879.1 COG0271 Stress-induced morphogen (activity unknown); hypothetical protein 316585 5626133 A1E_01410 Rickettsia canadensis str. McKiel hypothetical protein YP_001492012.1 316343 R 293613 CDS YP_001492013.1 157803464 5626286 316647..317888 1 NC_009879.1 COG2200 FOG: EAL domain; phosphatidylserine decarboxylase 317888 5626286 A1E_01415 Rickettsia canadensis str. McKiel phosphatidylserine decarboxylase YP_001492013.1 316647 D 293613 CDS YP_001492014.1 157803465 5626287 318046..319479 1 NC_009879.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 319479 murC 5626287 murC Rickettsia canadensis str. McKiel UDP-N-acetylmuramate--L-alanine ligase YP_001492014.1 318046 D 293613 CDS YP_001492015.1 157803466 5626288 319476..320369 1 NC_009879.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 320369 murB 5626288 murB Rickettsia canadensis str. McKiel UDP-N-acetylenolpyruvoylglucosamine reductase YP_001492015.1 319476 D 293613 CDS YP_001492016.1 157803467 5626289 320438..321502 1 NC_009879.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 321502 ddl 5626289 ddl Rickettsia canadensis str. McKiel D-alanine--D-alanine ligase YP_001492016.1 320438 D 293613 CDS YP_001492017.1 157803468 5626290 321499..322302 1 NC_009879.1 COG1589 Cell division septal protein; cell division protein ftsQ 322302 5626290 A1E_01435 Rickettsia canadensis str. McKiel cell division protein ftsQ YP_001492017.1 321499 D 293613 CDS YP_001492018.1 157803469 5626078 322331..323566 1 NC_009879.1 cell division protein FtsA 323566 5626078 A1E_01440 Rickettsia canadensis str. McKiel cell division protein FtsA YP_001492018.1 322331 D 293613 CDS YP_001492019.1 157803470 5626079 complement(323713..323946) 1 NC_009879.1 hypothetical protein 323946 5626079 A1E_01445 Rickettsia canadensis str. McKiel hypothetical protein YP_001492019.1 323713 R 293613 CDS YP_001492020.1 157803471 5626080 complement(325123..325590) 1 NC_009879.1 COG0849 Actin-like ATPase involved in cell division; hypothetical protein 325590 5626080 A1E_01450 Rickettsia canadensis str. McKiel hypothetical protein YP_001492020.1 325123 R 293613 CDS YP_001492021.1 157803472 5626081 complement(325580..326101) 1 NC_009879.1 cytochrome c 326101 5626081 A1E_01455 Rickettsia canadensis str. McKiel cytochrome c YP_001492021.1 325580 R 293613 CDS YP_001492022.1 157803473 5626082 326646..326819 1 NC_009879.1 COG3474 Cytochrome c2; D-alanine--D-alanine ligase 326819 ddl 5626082 ddl Rickettsia canadensis str. McKiel D-alanine--D-alanine ligase YP_001492022.1 326646 D 293613 CDS YP_001492023.1 157803474 5626217 complement(327248..328114) 1 NC_009879.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 328114 lpxC 5626217 lpxC Rickettsia canadensis str. McKiel UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001492023.1 327248 R 293613 CDS YP_001492024.1 157803475 5626218 complement(328307..329455) 1 NC_009879.1 COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; hypothetical protein 329455 5626218 A1E_01470 Rickettsia canadensis str. McKiel hypothetical protein YP_001492024.1 328307 R 293613 CDS YP_001492025.1 157803476 5626219 329882..331948 1 NC_009879.1 COG1530 Ribonucleases G and E; ribonuclease E 331948 5626219 A1E_01475 Rickettsia canadensis str. McKiel ribonuclease E YP_001492025.1 329882 D 293613 CDS YP_001492026.1 157803477 5626220 332200..333171 1 NC_009879.1 COG1612 Uncharacterized protein required for cytochrome oxidase assembly; cytochrome c oxidase assembly protein 333171 5626220 A1E_01480 Rickettsia canadensis str. McKiel cytochrome c oxidase assembly protein YP_001492026.1 332200 D 293613 CDS YP_001492027.1 157803478 5626221 333168..334079 1 NC_009879.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase C 334079 5626221 A1E_01485 Rickettsia canadensis str. McKiel ribosomal large subunit pseudouridine synthase C YP_001492027.1 333168 D 293613 CDS YP_001492028.1 157803479 5626073 334241..335422 1 NC_009879.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; penicillin-binding protein 4* 335422 5626073 A1E_01490 Rickettsia canadensis str. McKiel penicillin-binding protein 4* YP_001492028.1 334241 D 293613 CDS YP_001492029.1 157803480 5626074 335423..336244 1 NC_009879.1 COG0708 Exonuclease III; exodeoxyribonuclease III 336244 5626074 A1E_01495 Rickettsia canadensis str. McKiel exodeoxyribonuclease III YP_001492029.1 335423 D 293613 CDS YP_001492030.1 157803481 5626075 336312..337301 1 NC_009879.1 COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 337301 lpxC 5626075 lpxC Rickettsia canadensis str. McKiel UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001492030.1 336312 D 293613 CDS YP_001492031.1 157803482 5626076 337430..338416 1 NC_009879.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 338416 5626076 A1E_01505 Rickettsia canadensis str. McKiel pyruvate dehydrogenase subunit beta YP_001492031.1 337430 D 293613 CDS YP_001492032.1 157803483 5626077 complement(338639..340483) 1 NC_009879.1 GTP-binding protein 340483 5626077 A1E_01510 Rickettsia canadensis str. McKiel GTP-binding protein YP_001492032.1 338639 R 293613 CDS YP_001492033.1 157803484 5626845 340784..340918 1 NC_009879.1 hypothetical protein 340918 5626845 A1E_01515 Rickettsia canadensis str. McKiel hypothetical protein YP_001492033.1 340784 D 293613 CDS YP_001492034.1 157803485 5626846 340987..341250 1 NC_009879.1 COG1217 Predicted membrane GTPase involved in stress response; hypothetical protein 341250 5626846 A1E_01520 Rickettsia canadensis str. McKiel hypothetical protein YP_001492034.1 340987 D 293613 CDS YP_001492035.1 157803486 5626847 341499..342005 1 NC_009879.1 COG2825 Outer membrane protein; pyruvate dehydrogenase subunit beta 342005 5626847 A1E_01525 Rickettsia canadensis str. McKiel pyruvate dehydrogenase subunit beta YP_001492035.1 341499 D 293613 CDS YP_001492036.1 157803487 5626848 342140..343606 1 NC_009879.1 catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 343606 5626848 A1E_01530 Rickettsia canadensis str. McKiel isocitrate dehydrogenase YP_001492036.1 342140 D 293613 CDS YP_001492037.1 157803488 5626849 343783..344064 1 NC_009879.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G 344064 5626849 A1E_01535 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit G YP_001492037.1 343783 D 293613 CDS YP_001492038.1 157803489 5626877 344228..345277 1 NC_009879.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 345277 5626877 A1E_01540 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit B YP_001492038.1 344228 D 293613 CDS YP_001492039.1 157803490 5626878 345270..345917 1 NC_009879.1 Heme exporter protein B 345917 5626878 A1E_01545 Rickettsia canadensis str. McKiel Heme exporter protein B YP_001492039.1 345270 D 293613 CDS YP_001492040.1 157803491 5626879 345992..346393 1 NC_009879.1 COG1563 Predicted subunit of the Multisubunit Na+/H+ antiporter; hypothetical protein 346393 5626879 A1E_01550 Rickettsia canadensis str. McKiel hypothetical protein YP_001492040.1 345992 D 293613 CDS YP_001492041.1 157803492 5626880 346466..346999 1 NC_009879.1 COG0723 Rieske Fe-S protein; ubiquinol-cytochrome c reductase, iron-sulfur subunit 346999 5626880 A1E_01555 Rickettsia canadensis str. McKiel ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_001492041.1 346466 D 293613 CDS YP_001492042.1 157803493 5626881 347008..348204 1 NC_009879.1 COG1290 Cytochrome b subunit of the bc complex; cytochrome b 348204 5626881 A1E_01560 Rickettsia canadensis str. McKiel cytochrome b YP_001492042.1 347008 D 293613 CDS YP_001492043.1 157803494 5626722 348475..349143 1 NC_009879.1 COG2857 Cytochrome c1; cytochrome c1, heme protein precursor 349143 5626722 A1E_01565 Rickettsia canadensis str. McKiel cytochrome c1, heme protein precursor YP_001492043.1 348475 D 293613 CDS YP_001492044.1 157803495 5626723 349815..350318 1 NC_009879.1 COG0071 Molecular chaperone (small heat shock protein); putative monovalent cation/H+ antiporter subunit B 350318 5626723 A1E_01570 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit B YP_001492044.1 349815 D 293613 CDS YP_001492045.1 157803496 5626724 complement(350444..351496) 1 NC_009879.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 351496 prfB 5626724 prfB Rickettsia canadensis str. McKiel peptide chain release factor 2 YP_001492045.1 350444 R 293613 CDS YP_001492046.1 157803497 5626725 351834..353636 1 NC_009879.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 353636 5626725 A1E_01580 Rickettsia canadensis str. McKiel GTP-binding protein LepA YP_001492046.1 351834 D 293613 CDS YP_001492047.1 157803498 5626259 354301..354540 1 NC_009879.1 COG0481 Membrane GTPase LepA; hypothetical protein 354540 5626259 A1E_01585 Rickettsia canadensis str. McKiel hypothetical protein YP_001492047.1 354301 D 293613 CDS YP_001492048.1 157803499 5626260 complement(356372..357040) 1 NC_009879.1 COG0593 ATPase involved in DNA replication initiation; hypothetical protein 357040 5626260 A1E_01590 Rickettsia canadensis str. McKiel hypothetical protein YP_001492048.1 356372 R 293613 CDS YP_001492049.1 157803500 5626261 complement(357249..358304) 1 NC_009879.1 COG0628 Predicted permease; hypothetical protein 358304 5626261 A1E_01595 Rickettsia canadensis str. McKiel hypothetical protein YP_001492049.1 357249 R 293613 CDS YP_001492050.1 157803501 5626262 complement(358306..358845) 1 NC_009879.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 358845 5626262 A1E_01600 Rickettsia canadensis str. McKiel heat shock protein GrpE YP_001492050.1 358306 R 293613 CDS YP_001492051.1 157803502 5626465 358922..359641 1 NC_009879.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 359641 rph 5626465 rph Rickettsia canadensis str. McKiel ribonuclease PH YP_001492051.1 358922 D 293613 CDS YP_001492052.1 157803503 5626466 360130..360339 1 NC_009879.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; ribonuclease PH 360339 rph 5626466 rph Rickettsia canadensis str. McKiel ribonuclease PH YP_001492052.1 360130 D 293613 CDS YP_001492053.1 157803504 5626467 361264..361551 1 NC_009879.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 361551 groES 5626467 groES Rickettsia canadensis str. McKiel co-chaperonin GroES YP_001492053.1 361264 D 293613 CDS YP_001492054.1 157803505 5626468 361581..363224 1 NC_009879.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 363224 groEL 5626468 groEL Rickettsia canadensis str. McKiel chaperonin GroEL YP_001492054.1 361581 D 293613 CDS YP_001492055.1 157803506 5626469 363625..364005 1 NC_009879.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein 364005 5626469 A1E_01625 Rickettsia canadensis str. McKiel hypothetical protein YP_001492055.1 363625 D 293613 CDS YP_001492056.1 157803507 5626861 complement(364741..365274) 1 NC_009879.1 COG5342 Invasion protein B, involved in pathogenesis; chaperonin GroEL 365274 groEL 5626861 groEL Rickettsia canadensis str. McKiel chaperonin GroEL YP_001492056.1 364741 R 293613 CDS YP_001492057.1 157803508 5626862 complement(365271..366662) 1 NC_009879.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 366662 gltX 5626862 gltX Rickettsia canadensis str. McKiel glutamyl-tRNA synthetase YP_001492057.1 365271 R 293613 CDS YP_001492058.1 157803509 5626863 complement(366755..367465) 1 NC_009879.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 367465 5626863 A1E_01640 Rickettsia canadensis str. McKiel 3-demethylubiquinone-9 3-methyltransferase YP_001492058.1 366755 R 293613 CDS YP_001492059.1 157803510 5626864 367641..368408 1 NC_009879.1 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; 3-demethylubiquinone-9 3-methyltransferase 368408 5626864 A1E_01645 Rickettsia canadensis str. McKiel 3-demethylubiquinone-9 3-methyltransferase YP_001492059.1 367641 D 293613 CDS YP_001492060.1 157803511 5626865 complement(368952..372380) 1 NC_009879.1 Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein; acylglycerophosphoethanolamine acyltransferase 372380 5626865 A1E_01650 Rickettsia canadensis str. McKiel acylglycerophosphoethanolamine acyltransferase YP_001492060.1 368952 R 293613 CDS YP_001492061.1 157803512 5626840 complement(372407..372565) 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 372565 5626840 A1E_01655 Rickettsia canadensis str. McKiel hypothetical protein YP_001492061.1 372407 R 293613 CDS YP_001492062.1 157803513 5626841 372645..374189 1 NC_009879.1 propionyl-CoA carboxylase beta chain precursor 374189 5626841 A1E_01660 Rickettsia canadensis str. McKiel propionyl-CoA carboxylase beta chain precursor YP_001492062.1 372645 D 293613 CDS YP_001492063.1 157803514 5626842 374232..374357 1 NC_009879.1 hypothetical protein 374357 5626842 A1E_01665 Rickettsia canadensis str. McKiel hypothetical protein YP_001492063.1 374232 D 293613 CDS YP_001492064.1 157803515 5626843 374354..374755 1 NC_009879.1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); hypothetical protein 374755 5626843 A1E_01670 Rickettsia canadensis str. McKiel hypothetical protein YP_001492064.1 374354 D 293613 CDS YP_001492065.1 157803516 5626844 374891..376888 1 NC_009879.1 acylglycerophosphoethanolamine acyltransferase 376888 5626844 A1E_01675 Rickettsia canadensis str. McKiel acylglycerophosphoethanolamine acyltransferase YP_001492065.1 374891 D 293613 CDS YP_001492066.1 157803517 5626460 complement(378084..378203) 1 NC_009879.1 COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; hypothetical protein 378203 5626460 A1E_01680 Rickettsia canadensis str. McKiel hypothetical protein YP_001492066.1 378084 R 293613 CDS YP_001492067.1 157803518 5626461 complement(378459..381698) 1 NC_009879.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 381698 ileS 5626461 ileS Rickettsia canadensis str. McKiel isoleucyl-tRNA synthetase YP_001492067.1 378459 R 293613 CDS YP_001492068.1 157803519 5626462 complement(382168..382779) 1 NC_009879.1 COG5590 Uncharacterized conserved protein; isoleucyl-tRNA synthetase 382779 ileS 5626462 ileS Rickettsia canadensis str. McKiel isoleucyl-tRNA synthetase YP_001492068.1 382168 R 293613 CDS YP_001492069.1 157803520 5626463 382865..383065 1 NC_009879.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 383065 rpsU 5626463 rpsU Rickettsia canadensis str. McKiel 30S ribosomal protein S21 YP_001492069.1 382865 D 293613 CDS YP_001492070.1 157803521 5626464 complement(383216..383350) 1 NC_009879.1 COG0828 Ribosomal protein S21; hypothetical protein 383350 5626464 A1E_01700 Rickettsia canadensis str. McKiel hypothetical protein YP_001492070.1 383216 R 293613 CDS YP_001492071.1 157803522 5626817 383944..385746 1 NC_009879.1 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; nitrogen regulation protein ntrY 385746 5626817 A1E_01705 Rickettsia canadensis str. McKiel nitrogen regulation protein ntrY YP_001492071.1 383944 D 293613 CDS YP_001492072.1 157803523 5626819 388111..388425 1 NC_009879.1 hypothetical protein 388425 5626819 A1E_01710 Rickettsia canadensis str. McKiel hypothetical protein YP_001492072.1 388111 D 293613 CDS YP_001492073.1 157803524 5626820 388422..388532 1 NC_009879.1 hypothetical protein 388532 5626820 A1E_01715 Rickettsia canadensis str. McKiel hypothetical protein YP_001492073.1 388422 D 293613 CDS YP_001492074.1 157803525 5626821 388589..388687 1 NC_009879.1 hypothetical protein 388687 5626821 A1E_01720 Rickettsia canadensis str. McKiel hypothetical protein YP_001492074.1 388589 D 293613 CDS YP_001492075.1 157803526 5626249 389243..389380 1 NC_009879.1 hypothetical protein 389380 5626249 A1E_01725 Rickettsia canadensis str. McKiel hypothetical protein YP_001492075.1 389243 D 293613 CDS YP_001492076.1 157803527 5626250 389492..391237 1 NC_009879.1 COG0666 FOG: Ankyrin repeat; 30S ribosomal protein S21 391237 rpsU 5626250 rpsU Rickettsia canadensis str. McKiel 30S ribosomal protein S21 YP_001492076.1 389492 D 293613 CDS YP_001492077.1 157803528 5626251 complement(391306..391662) 1 NC_009879.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 391662 rnpA 5626251 rnpA Rickettsia canadensis str. McKiel ribonuclease P YP_001492077.1 391306 R 293613 CDS YP_001492078.1 157803529 5626252 complement(391682..391816) 1 NC_009879.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 391816 rpmH 5626252 rpmH Rickettsia canadensis str. McKiel 50S ribosomal protein L34 YP_001492078.1 391682 R 293613 CDS YP_001492079.1 157803530 5626253 complement(391948..392301) 1 NC_009879.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 392301 rplT 5626253 rplT Rickettsia canadensis str. McKiel 50S ribosomal protein L20 YP_001492079.1 391948 R 293613 CDS YP_001492080.1 157803531 5626653 complement(392317..392523) 1 NC_009879.1 COG0291 Ribosomal protein L35; 50S ribosomal protein L35 392523 rpmI 5626653 rpmI Rickettsia canadensis str. McKiel 50S ribosomal protein L35 YP_001492080.1 392317 R 293613 CDS YP_001492081.1 157803532 5626654 392810..393487 1 NC_009879.1 COG0602 Organic radical activating enzymes; 50S ribosomal protein L35 393487 rpmI 5626654 rpmI Rickettsia canadensis str. McKiel 50S ribosomal protein L35 YP_001492081.1 392810 D 293613 CDS YP_001492082.1 157803533 5626655 393570..394184 1 NC_009879.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 394184 5626655 A1E_01760 Rickettsia canadensis str. McKiel 50S ribosomal protein L25/general stress protein Ctc YP_001492082.1 393570 D 293613 CDS YP_001492083.1 157803534 5626656 394400..394957 1 NC_009879.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 394957 5626656 A1E_01765 Rickettsia canadensis str. McKiel peptidyl-tRNA hydrolase YP_001492083.1 394400 D 293613 CDS YP_001492084.1 157803535 5626657 395240..395416 1 NC_009879.1 COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 395416 5626657 A1E_01770 Rickettsia canadensis str. McKiel peptidyl-tRNA hydrolase YP_001492084.1 395240 D 293613 CDS YP_001492085.1 157803536 5626476 395577..396674 1 NC_009879.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 396674 5626476 A1E_01775 Rickettsia canadensis str. McKiel GTP-dependent nucleic acid-binding protein EngD YP_001492085.1 395577 D 293613 CDS YP_001492086.1 157803537 5626477 396688..396903 1 NC_009879.1 hypothetical protein 396903 5626477 A1E_01780 Rickettsia canadensis str. McKiel hypothetical protein YP_001492086.1 396688 D 293613 CDS YP_001492087.1 157803538 5626478 397585..398814 1 NC_009879.1 hypothetical protein 398814 5626478 A1E_01785 Rickettsia canadensis str. McKiel hypothetical protein YP_001492087.1 397585 D 293613 CDS YP_001492088.1 157803539 5626479 complement(399150..399293) 1 NC_009879.1 hypothetical protein 399293 5626479 A1E_01790 Rickettsia canadensis str. McKiel hypothetical protein YP_001492088.1 399150 R 293613 CDS YP_001492089.1 157803540 5626480 complement(399405..399518) 1 NC_009879.1 hypothetical protein 399518 5626480 A1E_01795 Rickettsia canadensis str. McKiel hypothetical protein YP_001492089.1 399405 R 293613 CDS YP_001492090.1 157803541 5626530 complement(399878..400150) 1 NC_009879.1 hypothetical protein 400150 5626530 A1E_01800 Rickettsia canadensis str. McKiel hypothetical protein YP_001492090.1 399878 R 293613 CDS YP_001492091.1 157803542 5626531 complement(400155..400316) 1 NC_009879.1 hypothetical protein 400316 5626531 A1E_01805 Rickettsia canadensis str. McKiel hypothetical protein YP_001492091.1 400155 R 293613 CDS YP_001492092.1 157803543 5626532 complement(400327..400533) 1 NC_009879.1 hypothetical protein 400533 5626532 A1E_01810 Rickettsia canadensis str. McKiel hypothetical protein YP_001492092.1 400327 R 293613 CDS YP_001492093.1 157803544 5626533 complement(400704..402545) 1 NC_009879.1 hypothetical protein 402545 5626533 A1E_01815 Rickettsia canadensis str. McKiel hypothetical protein YP_001492093.1 400704 R 293613 CDS YP_001492094.1 157803545 5626534 complement(403657..403941) 1 NC_009879.1 hypothetical protein 403941 5626534 A1E_01820 Rickettsia canadensis str. McKiel hypothetical protein YP_001492094.1 403657 R 293613 CDS YP_001492095.1 157803546 5626316 complement(404050..405441) 1 NC_009879.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 405441 dnaA 5626316 dnaA Rickettsia canadensis str. McKiel chromosomal replication initiation protein YP_001492095.1 404050 R 293613 CDS YP_001492096.1 157803547 5626317 complement(405472..405798) 1 NC_009879.1 hypothetical protein 405798 5626317 A1E_01830 Rickettsia canadensis str. McKiel hypothetical protein YP_001492096.1 405472 R 293613 CDS YP_001492097.1 157803548 5626318 406123..406386 1 NC_009879.1 hypothetical protein 406386 5626318 A1E_01835 Rickettsia canadensis str. McKiel hypothetical protein YP_001492097.1 406123 D 293613 CDS YP_001492098.1 157803549 5626319 406399..409758 1 NC_009879.1 hypothetical protein 409758 5626319 A1E_01840 Rickettsia canadensis str. McKiel hypothetical protein YP_001492098.1 406399 D 293613 CDS YP_001492099.1 157803550 5626320 409875..411311 1 NC_009879.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 411311 murE 5626320 murE Rickettsia canadensis str. McKiel UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001492099.1 409875 D 293613 CDS YP_001492100.1 157803551 5626254 411460..412968 1 NC_009879.1 hypothetical protein 412968 5626254 A1E_01850 Rickettsia canadensis str. McKiel hypothetical protein YP_001492100.1 411460 D 293613 CDS YP_001492101.1 157803552 5626255 413061..414146 1 NC_009879.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 414146 mraY 5626255 mraY Rickettsia canadensis str. McKiel phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001492101.1 413061 D 293613 CDS YP_001492102.1 157803553 5626256 414312..415991 1 NC_009879.1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; Actin polymerization protein RickA 415991 5626256 A1E_01860 Rickettsia canadensis str. McKiel Actin polymerization protein RickA YP_001492102.1 414312 D 293613 CDS YP_001492103.1 157803554 5626257 complement(416516..416677) 1 NC_009879.1 COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit; hypothetical protein 416677 5626257 A1E_01865 Rickettsia canadensis str. McKiel hypothetical protein YP_001492103.1 416516 R 293613 CDS YP_001492104.1 157803555 5626258 complement(416760..416924) 1 NC_009879.1 COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; succinyl-CoA:3-ketoacid-coenzyme A transferase 416924 5626258 A1E_01870 Rickettsia canadensis str. McKiel succinyl-CoA:3-ketoacid-coenzyme A transferase YP_001492104.1 416760 R 293613 CDS YP_001492105.1 157803556 5626239 complement(417034..417243) 1 NC_009879.1 succinyl-CoA:3-ketoacid-coenzyme A transferase 417243 5626239 A1E_01875 Rickettsia canadensis str. McKiel succinyl-CoA:3-ketoacid-coenzyme A transferase YP_001492105.1 417034 R 293613 CDS YP_001492106.1 157803557 5626240 418000..418290 1 NC_009879.1 hypothetical protein 418290 5626240 A1E_01880 Rickettsia canadensis str. McKiel hypothetical protein YP_001492106.1 418000 D 293613 CDS YP_001492107.1 157803558 5626241 418398..418607 1 NC_009879.1 COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; hypothetical protein 418607 5626241 A1E_01885 Rickettsia canadensis str. McKiel hypothetical protein YP_001492107.1 418398 D 293613 CDS YP_001492108.1 157803559 5626242 418671..420788 1 NC_009879.1 COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG 420788 5626242 A1E_01890 Rickettsia canadensis str. McKiel ATP-dependent DNA helicase RecG YP_001492108.1 418671 D 293613 CDS YP_001492109.1 157803560 5626243 complement(421027..421248) 1 NC_009879.1 hypothetical protein 421248 5626243 A1E_01895 Rickettsia canadensis str. McKiel hypothetical protein YP_001492109.1 421027 R 293613 CDS YP_001492110.1 157803561 5626296 complement(421668..422414) 1 NC_009879.1 COG1135 ABC-type metal ion transport system, ATPase component; hypothetical protein 422414 5626296 A1E_01900 Rickettsia canadensis str. McKiel hypothetical protein YP_001492110.1 421668 R 293613 CDS YP_001492111.1 157803562 5626297 complement(422411..423916) 1 NC_009879.1 virulence factor mviN 423916 5626297 A1E_01905 Rickettsia canadensis str. McKiel virulence factor mviN YP_001492111.1 422411 R 293613 CDS YP_001492112.1 157803563 5626298 423983..424096 1 NC_009879.1 COG0728 Uncharacterized membrane protein, putative virulence factor; hypothetical protein 424096 5626298 A1E_01910 Rickettsia canadensis str. McKiel hypothetical protein YP_001492112.1 423983 D 293613 CDS YP_001492113.1 157803564 5626299 complement(424195..424722) 1 NC_009879.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 424722 5626299 A1E_01915 Rickettsia canadensis str. McKiel inorganic pyrophosphatase YP_001492113.1 424195 R 293613 CDS YP_001492114.1 157803565 5626300 complement(424973..425359) 1 NC_009879.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 425359 5626300 A1E_01920 Rickettsia canadensis str. McKiel cytochrome c-type biogenesis protein CcmE YP_001492114.1 424973 R 293613 CDS YP_001492115.1 157803566 5626337 complement(425461..426078) 1 NC_009879.1 COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems; Sco2 protein precursor 426078 5626337 A1E_01925 Rickettsia canadensis str. McKiel Sco2 protein precursor YP_001492115.1 425461 R 293613 CDS YP_001492116.1 157803567 5626338 complement(426084..427646) 1 NC_009879.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 427646 secD 5626338 secD Rickettsia canadensis str. McKiel preprotein translocase subunit SecD YP_001492116.1 426084 R 293613 CDS YP_001492117.1 157803568 5626339 complement(427630..428067) 1 NC_009879.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 428067 yajC 5626339 yajC Rickettsia canadensis str. McKiel preprotein translocase subunit YajC YP_001492117.1 427630 R 293613 CDS YP_001492118.1 157803569 5626341 complement(430629..431999) 1 NC_009879.1 magnesium transporter 431999 5626341 A1E_01940 Rickettsia canadensis str. McKiel magnesium transporter YP_001492118.1 430629 R 293613 CDS YP_001492119.1 157803570 5626596 complement(432412..432534) 1 NC_009879.1 COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); hypothetical protein 432534 5626596 A1E_01945 Rickettsia canadensis str. McKiel hypothetical protein YP_001492119.1 432412 R 293613 CDS YP_001492120.1 157803571 5626597 complement(432564..432743) 1 NC_009879.1 hypothetical protein 432743 5626597 A1E_01950 Rickettsia canadensis str. McKiel hypothetical protein YP_001492120.1 432564 R 293613 CDS YP_001492121.1 157803572 5626598 432878..433147 1 NC_009879.1 COG1943 Transposase and inactivated derivatives; hypothetical protein 433147 5626598 A1E_01955 Rickettsia canadensis str. McKiel hypothetical protein YP_001492121.1 432878 D 293613 CDS YP_001492122.1 157803573 5626312 complement(433475..434335) 1 NC_009879.1 COG0647 Predicted sugar phosphatases of the HAD superfamily; HAD family hydrolase 434335 5626312 A1E_01960 Rickettsia canadensis str. McKiel HAD family hydrolase YP_001492122.1 433475 R 293613 CDS YP_001492123.1 157803574 5626313 434443..436869 1 NC_009879.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 436869 gyrB 5626313 gyrB Rickettsia canadensis str. McKiel DNA gyrase subunit B YP_001492123.1 434443 D 293613 CDS YP_001492124.1 157803575 5626314 437074..438333 1 NC_009879.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 438333 5626314 A1E_01970 Rickettsia canadensis str. McKiel UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001492124.1 437074 D 293613 CDS YP_001492125.1 157803576 5626315 438501..438884 1 NC_009879.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 438884 rpoZ 5626315 rpoZ Rickettsia canadensis str. McKiel DNA-directed RNA polymerase subunit omega YP_001492125.1 438501 D 293613 CDS YP_001492126.1 157803577 5625950 438885..439280 1 NC_009879.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 439280 acpS 5625950 acpS Rickettsia canadensis str. McKiel 4'-phosphopantetheinyl transferase YP_001492126.1 438885 D 293613 CDS YP_001492127.1 157803578 5625951 complement(439525..440373) 1 NC_009879.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; protein export protein PrsA precursor 440373 5625951 A1E_01985 Rickettsia canadensis str. McKiel protein export protein PrsA precursor YP_001492127.1 439525 R 293613 CDS YP_001492128.1 157803579 5625952 440584..443304 1 NC_009879.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 443304 5625952 A1E_01990 Rickettsia canadensis str. McKiel preprotein translocase subunit SecA YP_001492128.1 440584 D 293613 CDS YP_001492129.1 157803580 5625953 443305..443454 1 NC_009879.1 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); nucleotidyltransferase/HEPN domain-containing protein 443454 5625953 A1E_01995 Rickettsia canadensis str. McKiel nucleotidyltransferase/HEPN domain-containing protein YP_001492129.1 443305 D 293613 CDS YP_001492130.1 157803581 5625954 444232..444456 1 NC_009879.1 ankyrin repeat-containing protein 444456 5625954 A1E_02000 Rickettsia canadensis str. McKiel ankyrin repeat-containing protein YP_001492130.1 444232 D 293613 CDS YP_001492131.1 157803582 5626069 444609..444818 1 NC_009879.1 hypothetical protein 444818 5626069 A1E_02005 Rickettsia canadensis str. McKiel hypothetical protein YP_001492131.1 444609 D 293613 CDS YP_001492132.1 157803583 5626070 444931..445146 1 NC_009879.1 COG0666 FOG: Ankyrin repeat; hypothetical protein 445146 5626070 A1E_02010 Rickettsia canadensis str. McKiel hypothetical protein YP_001492132.1 444931 D 293613 CDS YP_001492133.1 157803584 5626072 445734..445877 1 NC_009879.1 COG0286 Type I restriction-modification system methyltransferase subunit; Type I restriction-modification system, M subunit 445877 5626072 A1E_02015 Rickettsia canadensis str. McKiel Type I restriction-modification system, M subunit YP_001492133.1 445734 D 293613 CDS YP_001492134.1 157803585 5626443 445802..446044 1 NC_009879.1 Type I restriction-modification system, M subunit 446044 5626443 A1E_02020 Rickettsia canadensis str. McKiel Type I restriction-modification system, M subunit YP_001492134.1 445802 D 293613 CDS YP_001492135.1 157803586 5626444 complement(446915..447103) 1 NC_009879.1 COG0286 Type I restriction-modification system methyltransferase subunit; hypothetical protein 447103 5626444 A1E_02025 Rickettsia canadensis str. McKiel hypothetical protein YP_001492135.1 446915 R 293613 CDS YP_001492136.1 157803587 5626445 447424..448818 1 NC_009879.1 COG0591 Na+/proline symporter; Sodium/pantothenate symporter 448818 5626445 A1E_02030 Rickettsia canadensis str. McKiel Sodium/pantothenate symporter YP_001492136.1 447424 D 293613 CDS YP_001492137.1 157803588 5626446 complement(449353..451269) 1 NC_009879.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 451269 uvrC 5626446 uvrC Rickettsia canadensis str. McKiel excinuclease ABC subunit C YP_001492137.1 449353 R 293613 CDS YP_001492138.1 157803589 5626447 complement(451351..451884) 1 NC_009879.1 hypothetical protein 451884 5626447 A1E_02040 Rickettsia canadensis str. McKiel hypothetical protein YP_001492138.1 451351 R 293613 CDS YP_001492139.1 157803590 5626301 complement(452001..452111) 1 NC_009879.1 COG2847 Uncharacterized protein conserved in bacteria; hypothetical protein 452111 5626301 A1E_02045 Rickettsia canadensis str. McKiel hypothetical protein YP_001492139.1 452001 R 293613 CDS YP_001492140.1 157803591 5626302 complement(452588..453118) 1 NC_009879.1 COG0350 Methylated DNA-protein cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase 453118 5626302 A1E_02050 Rickettsia canadensis str. McKiel methylated-DNA--protein-cysteine methyltransferase YP_001492140.1 452588 R 293613 CDS YP_001492141.1 157803592 5626303 complement(454363..454545) 1 NC_009879.1 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Type I site-specific restriction-modification system, R (restriction) subunit 454545 5626303 A1E_02055 Rickettsia canadensis str. McKiel Type I site-specific restriction-modification system, R (restriction) subunit YP_001492141.1 454363 R 293613 CDS YP_001492142.1 157803593 5626304 456406..456855 1 NC_009879.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 456855 5626304 A1E_02060 Rickettsia canadensis str. McKiel cell division protein MraZ YP_001492142.1 456406 D 293613 CDS YP_001492143.1 157803594 5626305 456855..457781 1 NC_009879.1 COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW 457781 mraW 5626305 mraW Rickettsia canadensis str. McKiel S-adenosyl-methyltransferase MraW YP_001492143.1 456855 D 293613 CDS YP_001492144.1 157803595 5626013 457784..458173 1 NC_009879.1 COG5462 Predicted secreted (periplasmic) protein; cell division protein FtsL 458173 5626013 A1E_02070 Rickettsia canadensis str. McKiel cell division protein FtsL YP_001492144.1 457784 D 293613 CDS YP_001492145.1 157803596 5626014 458264..459949 1 NC_009879.1 penicillin-binding protein 459949 5626014 A1E_02075 Rickettsia canadensis str. McKiel penicillin-binding protein YP_001492145.1 458264 D 293613 CDS YP_001492146.1 157803597 5626015 460379..460900 1 NC_009879.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; hypothetical protein 460900 5626015 A1E_02080 Rickettsia canadensis str. McKiel hypothetical protein YP_001492146.1 460379 D 293613 CDS YP_001492147.1 157803598 5626016 460890..462671 1 NC_009879.1 penicillin-binding protein 462671 5626016 A1E_02085 Rickettsia canadensis str. McKiel penicillin-binding protein YP_001492147.1 460890 D 293613 CDS YP_001492148.1 157803599 5626017 462710..462850 1 NC_009879.1 hypothetical protein 462850 5626017 A1E_02090 Rickettsia canadensis str. McKiel hypothetical protein YP_001492148.1 462710 D 293613 CDS YP_001492149.1 157803600 5626331 463165..463344 1 NC_009879.1 hypothetical protein 463344 5626331 A1E_02095 Rickettsia canadensis str. McKiel hypothetical protein YP_001492149.1 463165 D 293613 CDS YP_001492150.1 157803601 5626332 463781..464758 1 NC_009879.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; hypothetical protein 464758 5626332 A1E_02100 Rickettsia canadensis str. McKiel hypothetical protein YP_001492150.1 463781 D 293613 CDS YP_001492151.1 157803602 5626333 complement(465108..466859) 1 NC_009879.1 COG1357 Uncharacterized low-complexity proteins; hypothetical protein 466859 5626333 A1E_02105 Rickettsia canadensis str. McKiel hypothetical protein YP_001492151.1 465108 R 293613 CDS YP_001492152.1 157803603 5626334 complement(466846..468273) 1 NC_009879.1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; nitrogen assimilation regulatory protein NtrX 468273 5626334 A1E_02110 Rickettsia canadensis str. McKiel nitrogen assimilation regulatory protein NtrX YP_001492152.1 466846 R 293613 CDS YP_001492153.1 157803604 5626335 468487..468753 1 NC_009879.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit F 468753 5626335 A1E_02115 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit F YP_001492153.1 468487 D 293613 CDS YP_001492154.1 157803605 5626336 468896..470023 1 NC_009879.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 470023 5626336 A1E_02120 Rickettsia canadensis str. McKiel 2-octaprenyl-6-methoxyphenyl hydroxylase YP_001492154.1 468896 D 293613 CDS YP_001492155.1 157803606 5626105 470237..470419 1 NC_009879.1 hypothetical protein 470419 5626105 A1E_02125 Rickettsia canadensis str. McKiel hypothetical protein YP_001492155.1 470237 D 293613 CDS YP_001492156.1 157803607 5626106 470412..470531 1 NC_009879.1 hypothetical protein 470531 5626106 A1E_02130 Rickettsia canadensis str. McKiel hypothetical protein YP_001492156.1 470412 D 293613 CDS YP_001492157.1 157803608 5626107 470997..471071 1 NC_009879.1 hypothetical protein 471071 5626107 A1E_02135 Rickettsia canadensis str. McKiel hypothetical protein YP_001492157.1 470997 D 293613 CDS YP_001492158.1 157803609 5626108 471696..471911 1 NC_009879.1 hypothetical protein 471911 5626108 A1E_02140 Rickettsia canadensis str. McKiel hypothetical protein YP_001492158.1 471696 D 293613 CDS YP_001492159.1 157803610 5626109 471901..472050 1 NC_009879.1 hypothetical protein 472050 5626109 A1E_02145 Rickettsia canadensis str. McKiel hypothetical protein YP_001492159.1 471901 D 293613 CDS YP_001492160.1 157803611 5626110 472038..472241 1 NC_009879.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; hypothetical protein 472241 5626110 A1E_02150 Rickettsia canadensis str. McKiel hypothetical protein YP_001492160.1 472038 D 293613 CDS YP_001492161.1 157803612 5626018 472492..473823 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter 473823 5626018 A1E_02155 Rickettsia canadensis str. McKiel proline/betaine transporter YP_001492161.1 472492 D 293613 CDS YP_001492162.1 157803613 5626019 complement(473820..474467) 1 NC_009879.1 hypothetical protein 474467 5626019 A1E_02160 Rickettsia canadensis str. McKiel hypothetical protein YP_001492162.1 473820 R 293613 CDS YP_001492164.1 157803615 5626022 complement(476156..476395) 1 NC_009879.1 hypothetical protein 476395 5626022 A1E_02170 Rickettsia canadensis str. McKiel hypothetical protein YP_001492164.1 476156 R 293613 CDS YP_001492165.1 157803616 5626083 complement(476698..476994) 1 NC_009879.1 hypothetical protein 476994 5626083 A1E_02175 Rickettsia canadensis str. McKiel hypothetical protein YP_001492165.1 476698 R 293613 CDS YP_001492166.1 157803617 5626084 477733..477912 1 NC_009879.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein 477912 5626084 A1E_02180 Rickettsia canadensis str. McKiel hypothetical protein YP_001492166.1 477733 D 293613 CDS YP_001492167.1 157803618 5626085 477924..479159 1 NC_009879.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 479159 5626085 A1E_02185 Rickettsia canadensis str. McKiel tyrosyl-tRNA synthetase YP_001492167.1 477924 D 293613 CDS YP_001492168.1 157803619 5626086 479982..480158 1 NC_009879.1 COG0162 Tyrosyl-tRNA synthetase; hypothetical protein 480158 5626086 A1E_02190 Rickettsia canadensis str. McKiel hypothetical protein YP_001492168.1 479982 D 293613 CDS YP_001492169.1 157803620 5626087 480266..481120 1 NC_009879.1 COG1189 Predicted rRNA methylase; tyrosyl-tRNA synthetase 481120 5626087 A1E_02195 Rickettsia canadensis str. McKiel tyrosyl-tRNA synthetase YP_001492169.1 480266 D 293613 CDS YP_001492170.1 157803621 5626088 481400..481777 1 NC_009879.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 481777 5626088 A1E_02200 Rickettsia canadensis str. McKiel hypothetical protein YP_001492170.1 481400 D 293613 CDS YP_001492171.1 157803622 5626395 481900..483411 1 NC_009879.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 483411 nusA 5626395 nusA Rickettsia canadensis str. McKiel transcription elongation factor NusA YP_001492171.1 481900 D 293613 CDS YP_001492172.1 157803623 5626396 483625..486126 1 NC_009879.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 486126 infB 5626396 infB Rickettsia canadensis str. McKiel translation initiation factor IF-2 YP_001492172.1 483625 D 293613 CDS YP_001492173.1 157803624 5626397 486434..488014 1 NC_009879.1 COG0532 Translation initiation factor 2 (IF-2; GTPase); hypothetical protein 488014 5626397 A1E_02215 Rickettsia canadensis str. McKiel hypothetical protein YP_001492173.1 486434 D 293613 CDS YP_001492174.1 157803625 5626398 complement(488043..488723) 1 NC_009879.1 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; translation initiation factor IF-2 488723 infB 5626398 infB Rickettsia canadensis str. McKiel translation initiation factor IF-2 YP_001492174.1 488043 R 293613 CDS YP_001492175.1 157803626 5626399 complement(488806..489531) 1 NC_009879.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 489531 recO 5626399 recO Rickettsia canadensis str. McKiel DNA repair protein RecO YP_001492175.1 488806 R 293613 CDS YP_001492176.1 157803627 5626400 complement(489730..490062) 1 NC_009879.1 COG0191 Fructose/tagatose bisphosphate aldolase; DNA repair protein RecO 490062 recO 5626400 recO Rickettsia canadensis str. McKiel DNA repair protein RecO YP_001492176.1 489730 R 293613 CDS YP_001492177.1 157803628 5626748 complement(490059..491399) 1 NC_009879.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 491399 5626748 A1E_02235 Rickettsia canadensis str. McKiel DNA repair protein RadA YP_001492177.1 490059 R 293613 CDS YP_001492178.1 157803629 5626749 complement(491538..492110) 1 NC_009879.1 COG0742 N6-adenine-specific methylase; N6-adenine-specific methylase 492110 5626749 A1E_02240 Rickettsia canadensis str. McKiel N6-adenine-specific methylase YP_001492178.1 491538 R 293613 CDS YP_001492179.1 157803630 5626750 complement(492119..494989) 1 NC_009879.1 COG1357 Uncharacterized low-complexity proteins; hypothetical protein 494989 5626750 A1E_02245 Rickettsia canadensis str. McKiel hypothetical protein YP_001492179.1 492119 R 293613 CDS YP_001492180.1 157803631 5626751 complement(495040..495729) 1 NC_009879.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; repair protein 495729 5626751 A1E_02250 Rickettsia canadensis str. McKiel repair protein YP_001492180.1 495040 R 293613 CDS YP_001492181.1 157803632 5626752 495922..496068 1 NC_009879.1 hypothetical protein 496068 5626752 A1E_02255 Rickettsia canadensis str. McKiel hypothetical protein YP_001492181.1 495922 D 293613 CDS YP_001492182.1 157803633 5626753 496497..496643 1 NC_009879.1 COG0814 Amino acid permeases; hypothetical protein 496643 5626753 A1E_02260 Rickettsia canadensis str. McKiel hypothetical protein YP_001492182.1 496497 D 293613 CDS YP_001492183.1 157803634 5626590 complement(496743..498227) 1 NC_009879.1 unwinds double stranded DNA; replicative DNA helicase 498227 5626590 A1E_02265 Rickettsia canadensis str. McKiel replicative DNA helicase YP_001492183.1 496743 R 293613 CDS YP_001492184.1 157803635 5626591 complement(498715..499350) 1 NC_009879.1 COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; aromatic acid decarboxylase 499350 5626591 A1E_02270 Rickettsia canadensis str. McKiel aromatic acid decarboxylase YP_001492184.1 498715 R 293613 CDS YP_001492185.1 157803636 5626592 499345..501291 1 NC_009879.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 501291 5626592 A1E_02275 Rickettsia canadensis str. McKiel primosome assembly protein PriA YP_001492185.1 499345 D 293613 CDS YP_001492186.1 157803637 5626593 complement(501787..501903) 1 NC_009879.1 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; hypothetical protein 501903 5626593 A1E_02280 Rickettsia canadensis str. McKiel hypothetical protein YP_001492186.1 501787 R 293613 CDS YP_001492187.1 157803638 5626594 502061..503053 1 NC_009879.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 503053 5626594 A1E_02285 Rickettsia canadensis str. McKiel delta-aminolevulinic acid dehydratase YP_001492187.1 502061 D 293613 CDS YP_001492188.1 157803639 5626595 503168..504733 1 NC_009879.1 COG0113 Delta-aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase 504733 5626595 A1E_02290 Rickettsia canadensis str. McKiel delta-aminolevulinic acid dehydratase YP_001492188.1 503168 D 293613 CDS YP_001492189.1 157803640 5626600 complement(504723..506093) 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 506093 5626600 A1E_02295 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit N YP_001492189.1 504723 R 293613 CDS YP_001492190.1 157803641 5626601 506111..506275 1 NC_009879.1 hypothetical protein 506275 5626601 A1E_02300 Rickettsia canadensis str. McKiel hypothetical protein YP_001492190.1 506111 D 293613 CDS YP_001492191.1 157803642 5626602 506505..506684 1 NC_009879.1 COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); transposase 506684 5626602 A1E_02305 Rickettsia canadensis str. McKiel transposase YP_001492191.1 506505 D 293613 CDS YP_001492192.1 157803643 5626603 507004..507237 1 NC_009879.1 hypothetical protein 507237 5626603 A1E_02310 Rickettsia canadensis str. McKiel hypothetical protein YP_001492192.1 507004 D 293613 CDS YP_001492193.1 157803644 5626604 507267..507389 1 NC_009879.1 hypothetical protein 507389 5626604 A1E_02315 Rickettsia canadensis str. McKiel hypothetical protein YP_001492193.1 507267 D 293613 CDS YP_001492194.1 157803645 5626605 507737..508609 1 NC_009879.1 hypothetical protein 508609 5626605 A1E_02320 Rickettsia canadensis str. McKiel hypothetical protein YP_001492194.1 507737 D 293613 CDS YP_001492195.1 157803646 5626760 508865..508969 1 NC_009879.1 COG1943 Transposase and inactivated derivatives; hypothetical protein 508969 5626760 A1E_02325 Rickettsia canadensis str. McKiel hypothetical protein YP_001492195.1 508865 D 293613 CDS YP_001492196.1 157803647 5626761 509686..510792 1 NC_009879.1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; hypothetical protein 510792 5626761 A1E_02330 Rickettsia canadensis str. McKiel hypothetical protein YP_001492196.1 509686 D 293613 CDS YP_001492197.1 157803648 5626762 510902..512134 1 NC_009879.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 512134 5626762 A1E_02335 Rickettsia canadensis str. McKiel cysteine desulfurase YP_001492197.1 510902 D 293613 CDS YP_001492198.1 157803649 5626763 512223..512624 1 NC_009879.1 COG0822 NifU homolog involved in Fe-S cluster formation; scaffold protein 512624 5626763 A1E_02340 Rickettsia canadensis str. McKiel scaffold protein YP_001492198.1 512223 D 293613 CDS YP_001492199.1 157803650 5626764 512621..512953 1 NC_009879.1 COG0316 Uncharacterized conserved protein; Iron-sulfur cluster assembly accessory protein 512953 5626764 A1E_02345 Rickettsia canadensis str. McKiel Iron-sulfur cluster assembly accessory protein YP_001492199.1 512621 D 293613 CDS YP_001492200.1 157803651 5626765 513083..514399 1 NC_009879.1 COG0531 Amino acid transporters; putrescine-ornithine antiporter 514399 5626765 A1E_02350 Rickettsia canadensis str. McKiel putrescine-ornithine antiporter YP_001492200.1 513083 D 293613 CDS YP_001492201.1 157803652 5626423 514480..516357 1 NC_009879.1 COG0006 Xaa-Pro aminopeptidase; hypothetical protein 516357 5626423 A1E_02355 Rickettsia canadensis str. McKiel hypothetical protein YP_001492201.1 514480 D 293613 CDS YP_001492202.1 157803653 5626426 complement(516744..517727) 1 NC_009879.1 octaprenyl-diphosphate synthase 517727 5626426 A1E_02360 Rickettsia canadensis str. McKiel octaprenyl-diphosphate synthase YP_001492202.1 516744 R 293613 CDS YP_001492203.1 157803654 5626213 complement(517839..519500) 1 NC_009879.1 COG0142 Geranylgeranyl pyrophosphate synthase; hypothetical protein 519500 5626213 A1E_02365 Rickettsia canadensis str. McKiel hypothetical protein YP_001492203.1 517839 R 293613 CDS YP_001492204.1 157803655 5626214 complement(519660..521171) 1 NC_009879.1 COG3202 ATP/ADP translocase; ADP,ATP carrier protein 521171 5626214 A1E_02370 Rickettsia canadensis str. McKiel ADP,ATP carrier protein YP_001492204.1 519660 R 293613 CDS YP_001492205.1 157803656 5626215 complement(521420..521797) 1 NC_009879.1 COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 521797 5626215 A1E_02375 Rickettsia canadensis str. McKiel transposase IS200-family protein YP_001492205.1 521420 R 293613 CDS YP_001492206.1 157803657 5626216 522057..523307 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; ampG protein 523307 5626216 A1E_02380 Rickettsia canadensis str. McKiel ampG protein YP_001492206.1 522057 D 293613 CDS YP_001492207.1 157803658 5626811 523773..524414 1 NC_009879.1 lysine efflux permease 524414 5626811 A1E_02385 Rickettsia canadensis str. McKiel lysine efflux permease YP_001492207.1 523773 D 293613 CDS YP_001492208.1 157803659 5626812 524392..525072 1 NC_009879.1 hypothetical protein 525072 5626812 A1E_02390 Rickettsia canadensis str. McKiel hypothetical protein YP_001492208.1 524392 D 293613 CDS YP_001492209.1 157803660 5626813 525059..525841 1 NC_009879.1 COG1279 Lysine efflux permease; hypothetical protein 525841 5626813 A1E_02395 Rickettsia canadensis str. McKiel hypothetical protein YP_001492209.1 525059 D 293613 CDS YP_001492210.1 157803661 5626814 525834..526847 1 NC_009879.1 COG0457 FOG: TPR repeat; hypothetical protein 526847 5626814 A1E_02400 Rickettsia canadensis str. McKiel hypothetical protein YP_001492210.1 525834 D 293613 CDS YP_001492211.1 157803662 5626815 complement(527021..527740) 1 NC_009879.1 hypothetical protein 527740 5626815 A1E_02405 Rickettsia canadensis str. McKiel hypothetical protein YP_001492211.1 527021 R 293613 CDS YP_001492212.1 157803663 5626816 527861..528004 1 NC_009879.1 COG2945 Predicted hydrolase of the alpha/beta superfamily; hypothetical protein 528004 5626816 A1E_02410 Rickettsia canadensis str. McKiel hypothetical protein YP_001492212.1 527861 D 293613 CDS YP_001492213.1 157803664 5625981 complement(528159..528599) 1 NC_009879.1 COG5622 Protein required for attachment to host cells; hypothetical protein 528599 5625981 A1E_02415 Rickettsia canadensis str. McKiel hypothetical protein YP_001492213.1 528159 R 293613 CDS YP_001492214.1 157803665 5625982 complement(528641..529228) 1 NC_009879.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; scaffold protein 529228 5625982 A1E_02420 Rickettsia canadensis str. McKiel scaffold protein YP_001492214.1 528641 R 293613 CDS YP_001492215.1 157803666 5625983 529456..530448 1 NC_009879.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 530448 5625983 A1E_02425 Rickettsia canadensis str. McKiel tryptophanyl-tRNA synthetase YP_001492215.1 529456 D 293613 CDS YP_001492216.1 157803667 5625985 complement(531967..532101) 1 NC_009879.1 COG0180 Tryptophanyl-tRNA synthetase; hypothetical protein 532101 5625985 A1E_02430 Rickettsia canadensis str. McKiel hypothetical protein YP_001492216.1 531967 R 293613 CDS YP_001492217.1 157803668 5625915 complement(532198..533103) 1 NC_009879.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 533103 hemC 5625915 hemC Rickettsia canadensis str. McKiel porphobilinogen deaminase YP_001492217.1 532198 R 293613 CDS YP_001492218.1 157803669 5625916 complement(533100..533324) 1 NC_009879.1 microcin C7 resistance protein 533324 5625916 A1E_02440 Rickettsia canadensis str. McKiel microcin C7 resistance protein YP_001492218.1 533100 R 293613 CDS YP_001492219.1 157803670 5625917 complement(533531..533659) 1 NC_009879.1 hypothetical protein 533659 5625917 A1E_02445 Rickettsia canadensis str. McKiel hypothetical protein YP_001492219.1 533531 R 293613 CDS YP_001492220.1 157803671 5625918 complement(533637..533792) 1 NC_009879.1 hypothetical protein 533792 5625918 A1E_02450 Rickettsia canadensis str. McKiel hypothetical protein YP_001492220.1 533637 R 293613 CDS YP_001492221.1 157803672 5625919 533819..533959 1 NC_009879.1 COG0181 Porphobilinogen deaminase; hypothetical protein 533959 5625919 A1E_02455 Rickettsia canadensis str. McKiel hypothetical protein YP_001492221.1 533819 D 293613 CDS YP_001492222.1 157803673 5625920 complement(534261..534542) 1 NC_009879.1 alkaline phosphatase synthesis sensor protein phor (phor) 534542 5625920 A1E_02460 Rickettsia canadensis str. McKiel alkaline phosphatase synthesis sensor protein phor (phor) YP_001492222.1 534261 R 293613 CDS YP_001492223.1 157803674 5626375 complement(536315..536452) 1 NC_009879.1 COG0642 Signal transduction histidine kinase; hypothetical protein 536452 5626375 A1E_02465 Rickettsia canadensis str. McKiel hypothetical protein YP_001492223.1 536315 R 293613 CDS YP_001492224.1 157803675 5626376 complement(536514..537344) 1 NC_009879.1 COG0354 Predicted aminomethyltransferase related to GcvT; glycine cleavage T-protein 537344 5626376 A1E_02470 Rickettsia canadensis str. McKiel glycine cleavage T-protein YP_001492224.1 536514 R 293613 CDS YP_001492225.1 157803676 5626377 537460..538251 1 NC_009879.1 COG1723 Uncharacterized conserved protein; hypothetical protein 538251 5626377 A1E_02475 Rickettsia canadensis str. McKiel hypothetical protein YP_001492225.1 537460 D 293613 CDS YP_001492226.1 157803677 5626378 538262..539116 1 NC_009879.1 COG0349 Ribonuclease D; ribonuclease D 539116 5626378 A1E_02480 Rickettsia canadensis str. McKiel ribonuclease D YP_001492226.1 538262 D 293613 CDS YP_001492227.1 157803678 5626379 complement(539212..539751) 1 NC_009879.1 COG0212 5-formyltetrahydrofolate cyclo-ligase; porphobilinogen deaminase 539751 hemC 5626379 hemC Rickettsia canadensis str. McKiel porphobilinogen deaminase YP_001492227.1 539212 R 293613 CDS YP_001492228.1 157803679 5626380 complement(539784..541163) 1 NC_009879.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 541163 5626380 A1E_02490 Rickettsia canadensis str. McKiel dihydrolipoamide dehydrogenase YP_001492228.1 539784 R 293613 CDS YP_001492229.1 157803680 5626417 complement(541323..541895) 1 NC_009879.1 biotin synthesis protein BioC 541895 5626417 A1E_02495 Rickettsia canadensis str. McKiel biotin synthesis protein BioC YP_001492229.1 541323 R 293613 CDS YP_001492230.1 157803681 5626418 complement(542226..542864) 1 NC_009879.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 542864 5626418 A1E_02500 Rickettsia canadensis str. McKiel hypothetical protein YP_001492230.1 542226 R 293613 CDS YP_001492231.1 157803682 5626419 complement(542885..543652) 1 NC_009879.1 hypothetical protein 543652 5626419 A1E_02505 Rickettsia canadensis str. McKiel hypothetical protein YP_001492231.1 542885 R 293613 CDS YP_001492232.1 157803683 5626420 complement(545051..545287) 1 NC_009879.1 dihydrolipoamide dehydrogenase 545287 5626420 A1E_02510 Rickettsia canadensis str. McKiel dihydrolipoamide dehydrogenase YP_001492232.1 545051 R 293613 CDS YP_001492233.1 157803684 5626421 545454..545579 1 NC_009879.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 545579 rpmJ 5626421 rpmJ Rickettsia canadensis str. McKiel 50S ribosomal protein L36 YP_001492233.1 545454 D 293613 CDS YP_001492234.1 157803685 5626422 545695..546453 1 NC_009879.1 COG0217 Uncharacterized conserved protein; hypothetical protein 546453 5626422 A1E_02520 Rickettsia canadensis str. McKiel hypothetical protein YP_001492234.1 545695 D 293613 CDS YP_001492235.1 157803686 5626794 546453..547199 1 NC_009879.1 UDP-N-acetylglucosamine pyrophosphorylase 547199 5626794 A1E_02525 Rickettsia canadensis str. McKiel UDP-N-acetylglucosamine pyrophosphorylase YP_001492235.1 546453 D 293613 CDS YP_001492236.1 157803687 5626796 complement(547555..547800) 1 NC_009879.1 hypothetical protein 547800 5626796 A1E_02535 Rickettsia canadensis str. McKiel hypothetical protein YP_001492236.1 547555 R 293613 CDS YP_001492237.1 157803688 5626797 548279..548389 1 NC_009879.1 COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); hypothetical protein 548389 5626797 A1E_02540 Rickettsia canadensis str. McKiel hypothetical protein YP_001492237.1 548279 D 293613 CDS YP_001492238.1 157803689 5626798 complement(548565..548828) 1 NC_009879.1 hypothetical protein 548828 5626798 A1E_02545 Rickettsia canadensis str. McKiel hypothetical protein YP_001492238.1 548565 R 293613 CDS YP_001492239.1 157803690 5625881 549276..549383 1 NC_009879.1 COG1694 Predicted pyrophosphatase; hypothetical protein 549383 5625881 A1E_02550 Rickettsia canadensis str. McKiel hypothetical protein YP_001492239.1 549276 D 293613 CDS YP_001492240.1 157803691 5625882 complement(549394..550422) 1 NC_009879.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 550422 5625882 A1E_02555 Rickettsia canadensis str. McKiel isopentenyl pyrophosphate isomerase YP_001492240.1 549394 R 293613 CDS YP_001492241.1 157803692 5625883 complement(550696..550860) 1 NC_009879.1 hypothetical protein 550860 5625883 A1E_02560 Rickettsia canadensis str. McKiel hypothetical protein YP_001492241.1 550696 R 293613 CDS YP_001492242.1 157803693 5625884 complement(551825..552034) 1 NC_009879.1 COG0474 Cation transport ATPase; hypothetical protein 552034 5625884 A1E_02565 Rickettsia canadensis str. McKiel hypothetical protein YP_001492242.1 551825 R 293613 CDS YP_001492243.1 157803694 5625886 complement(552624..553229) 1 NC_009879.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 553229 clpP 5625886 clpP Rickettsia canadensis str. McKiel ATP-dependent Clp protease proteolytic subunit YP_001492243.1 552624 R 293613 CDS YP_001492244.1 157803695 5626497 complement(553367..555073) 1 NC_009879.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 555073 rpsA 5626497 rpsA Rickettsia canadensis str. McKiel 30S ribosomal protein S1 YP_001492244.1 553367 R 293613 CDS YP_001492245.1 157803696 5626498 complement(555226..555882) 1 NC_009879.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 555882 cmk 5626498 cmk Rickettsia canadensis str. McKiel cytidylate kinase YP_001492245.1 555226 R 293613 CDS YP_001492246.1 157803697 5626500 556444..556833 1 NC_009879.1 hypothetical protein 556833 5626500 A1E_02585 Rickettsia canadensis str. McKiel hypothetical protein YP_001492246.1 556444 D 293613 CDS YP_001492247.1 157803698 5626894 557416..557580 1 NC_009879.1 hypothetical protein 557580 5626894 A1E_02590 Rickettsia canadensis str. McKiel hypothetical protein YP_001492247.1 557416 D 293613 CDS YP_001492248.1 157803699 5626895 557495..557692 1 NC_009879.1 COG0283 Cytidylate kinase; hypothetical protein 557692 5626895 A1E_02595 Rickettsia canadensis str. McKiel hypothetical protein YP_001492248.1 557495 D 293613 CDS YP_001492249.1 157803700 5626896 557898..558209 1 NC_009879.1 COG2801 Transposase and inactivated derivatives; integrase catalytic subunit 558209 5626896 A1E_02600 Rickettsia canadensis str. McKiel integrase catalytic subunit YP_001492249.1 557898 D 293613 CDS YP_001492250.1 157803701 5626897 558971..559678 1 NC_009879.1 hypothetical protein 559678 5626897 A1E_02605 Rickettsia canadensis str. McKiel hypothetical protein YP_001492250.1 558971 D 293613 CDS YP_001492251.1 157803702 5626898 complement(559707..560798) 1 NC_009879.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein 560798 5626898 A1E_02610 Rickettsia canadensis str. McKiel hypothetical protein YP_001492251.1 559707 R 293613 CDS YP_001492252.1 157803703 5626899 complement(560805..562115) 1 NC_009879.1 proline/betaine transporter 562115 5626899 A1E_02615 Rickettsia canadensis str. McKiel proline/betaine transporter YP_001492252.1 560805 R 293613 CDS YP_001492253.1 157803704 5626716 complement(562214..562435) 1 NC_009879.1 conjugal transfer protein TraD 562435 5626716 A1E_02620 Rickettsia canadensis str. McKiel conjugal transfer protein TraD YP_001492253.1 562214 R 293613 CDS YP_001492254.1 157803705 5626717 563083..563202 1 NC_009879.1 conjugal transfer protein TraA 563202 5626717 A1E_02625 Rickettsia canadensis str. McKiel conjugal transfer protein TraA YP_001492254.1 563083 D 293613 CDS YP_001492255.1 157803706 5626718 563202..563384 1 NC_009879.1 conjugal transfer protein TraA 563384 5626718 A1E_02630 Rickettsia canadensis str. McKiel conjugal transfer protein TraA YP_001492255.1 563202 D 293613 CDS YP_001492256.1 157803707 5626719 563521..563775 1 NC_009879.1 conjugal transfer protein TraA 563775 5626719 A1E_02635 Rickettsia canadensis str. McKiel conjugal transfer protein TraA YP_001492256.1 563521 D 293613 CDS YP_001492257.1 157803708 5626720 564150..564296 1 NC_009879.1 conjugal transfer protein TraA 564296 5626720 A1E_02640 Rickettsia canadensis str. McKiel conjugal transfer protein TraA YP_001492257.1 564150 D 293613 CDS YP_001492258.1 157803709 5626721 564286..564438 1 NC_009879.1 hypothetical protein 564438 5626721 A1E_02645 Rickettsia canadensis str. McKiel hypothetical protein YP_001492258.1 564286 D 293613 CDS YP_001492259.1 157803710 5626658 564556..564789 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; conjugal transfer protein TraA 564789 5626658 A1E_02650 Rickettsia canadensis str. McKiel conjugal transfer protein TraA YP_001492259.1 564556 D 293613 CDS YP_001492260.1 157803711 5626659 565561..566427 1 NC_009879.1 conjugal transfer protein TraA 566427 5626659 A1E_02655 Rickettsia canadensis str. McKiel conjugal transfer protein TraA YP_001492260.1 565561 D 293613 CDS YP_001492261.1 157803712 5626660 complement(566393..566539) 1 NC_009879.1 putative conjugative transfer protein TraD 566539 5626660 A1E_02660 Rickettsia canadensis str. McKiel putative conjugative transfer protein TraD YP_001492261.1 566393 R 293613 CDS YP_001492262.1 157803713 5626661 complement(566600..566956) 1 NC_009879.1 COG0358 DNA primase (bacterial type); putative conjugative transfer protein TraD 566956 5626661 A1E_02665 Rickettsia canadensis str. McKiel putative conjugative transfer protein TraD YP_001492262.1 566600 R 293613 CDS YP_001492263.1 157803714 5626662 complement(567115..567324) 1 NC_009879.1 TPR repeat-containing protein 567324 5626662 A1E_02670 Rickettsia canadensis str. McKiel TPR repeat-containing protein YP_001492263.1 567115 R 293613 CDS YP_001492264.1 157803715 5626663 complement(567420..567593) 1 NC_009879.1 TPR repeat-containing protein 567593 5626663 A1E_02675 Rickettsia canadensis str. McKiel TPR repeat-containing protein YP_001492264.1 567420 R 293613 CDS YP_001492265.1 157803716 5626099 complement(567678..567809) 1 NC_009879.1 hypothetical protein 567809 5626099 A1E_02680 Rickettsia canadensis str. McKiel hypothetical protein YP_001492265.1 567678 R 293613 CDS YP_001492266.1 157803717 5626100 complement(568354..568881) 1 NC_009879.1 conjugative transfer protein TraG 568881 5626100 A1E_02685 Rickettsia canadensis str. McKiel conjugative transfer protein TraG YP_001492266.1 568354 R 293613 CDS YP_001492267.1 157803718 5626101 complement(569712..569855) 1 NC_009879.1 hypothetical protein 569855 5626101 A1E_02690 Rickettsia canadensis str. McKiel hypothetical protein YP_001492267.1 569712 R 293613 CDS YP_001492268.1 157803719 5626102 complement(570724..570942) 1 NC_009879.1 hypothetical protein 570942 5626102 A1E_02695 Rickettsia canadensis str. McKiel hypothetical protein YP_001492268.1 570724 R 293613 CDS YP_001492269.1 157803720 5626103 571020..571616 1 NC_009879.1 hypothetical protein 571616 5626103 A1E_02700 Rickettsia canadensis str. McKiel hypothetical protein YP_001492269.1 571020 D 293613 CDS YP_001492270.1 157803721 5626104 complement(571895..572290) 1 NC_009879.1 hypothetical protein 572290 5626104 A1E_02705 Rickettsia canadensis str. McKiel hypothetical protein YP_001492270.1 571895 R 293613 CDS YP_001492271.1 157803722 5625875 complement(573827..574039) 1 NC_009879.1 putative conjugative transfer protein TraD 574039 5625875 A1E_02710 Rickettsia canadensis str. McKiel putative conjugative transfer protein TraD YP_001492271.1 573827 R 293613 CDS YP_001492272.1 157803723 5625876 complement(574374..574595) 1 NC_009879.1 F pilus assembly protein TraB 574595 5625876 A1E_02715 Rickettsia canadensis str. McKiel F pilus assembly protein TraB YP_001492272.1 574374 R 293613 CDS YP_001492273.1 157803724 5625877 complement(574965..575180) 1 NC_009879.1 COG0457 FOG: TPR repeat; hypothetical protein 575180 5625877 A1E_02720 Rickettsia canadensis str. McKiel hypothetical protein YP_001492273.1 574965 R 293613 CDS YP_001492274.1 157803725 5625878 complement(575746..575892) 1 NC_009879.1 COG0776 Bacterial nucleoid DNA-binding protein; hypothetical protein 575892 5625878 A1E_02725 Rickettsia canadensis str. McKiel hypothetical protein YP_001492274.1 575746 R 293613 CDS YP_001492275.1 157803726 5625879 complement(575892..576809) 1 NC_009879.1 COG0616 Periplasmic serine proteases (ClpP class); cytidylate kinase 576809 cmk 5625879 cmk Rickettsia canadensis str. McKiel cytidylate kinase YP_001492275.1 575892 R 293613 CDS YP_001492276.1 157803727 5625880 complement(577054..578430) 1 NC_009879.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 578430 rho 5625880 rho Rickettsia canadensis str. McKiel transcription termination factor Rho YP_001492276.1 577054 R 293613 CDS YP_001492277.1 157803728 5626557 complement(578946..580268) 1 NC_009879.1 COG0500 SAM-dependent methyltransferases; putative methyltransferase 580268 5626557 A1E_02740 Rickettsia canadensis str. McKiel putative methyltransferase YP_001492277.1 578946 R 293613 CDS YP_001492278.1 157803729 5626558 complement(580278..582035) 1 NC_009879.1 COG0608 Single-stranded DNA-specific exonuclease; transcription termination factor Rho 582035 rho 5626558 rho Rickettsia canadensis str. McKiel transcription termination factor Rho YP_001492278.1 580278 R 293613 CDS YP_001492279.1 157803730 5626559 complement(582212..583279) 1 NC_009879.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 583279 prfA 5626559 prfA Rickettsia canadensis str. McKiel peptide chain release factor 1 YP_001492279.1 582212 R 293613 CDS YP_001492280.1 157803731 5626560 complement(583562..584818) 1 NC_009879.1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; branched-chain alpha-keto acid dehydrogenase subunit E2 584818 5626560 A1E_02755 Rickettsia canadensis str. McKiel branched-chain alpha-keto acid dehydrogenase subunit E2 YP_001492280.1 583562 R 293613 CDS YP_001492281.1 157803732 5626561 complement(585057..585500) 1 NC_009879.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 585500 infC 5626561 infC Rickettsia canadensis str. McKiel translation initiation factor IF-3 YP_001492281.1 585057 R 293613 CDS YP_001492282.1 157803733 5626562 complement(585675..586010) 1 NC_009879.1 hypothetical protein 586010 5626562 A1E_02765 Rickettsia canadensis str. McKiel hypothetical protein YP_001492282.1 585675 R 293613 CDS YP_001492283.1 157803734 5626866 complement(585997..586170) 1 NC_009879.1 hypothetical protein 586170 5626866 A1E_02770 Rickettsia canadensis str. McKiel hypothetical protein YP_001492283.1 585997 R 293613 CDS YP_001492284.1 157803735 5626867 complement(586361..586615) 1 NC_009879.1 hypothetical protein 586615 5626867 A1E_02775 Rickettsia canadensis str. McKiel hypothetical protein YP_001492284.1 586361 R 293613 CDS YP_001492285.1 157803736 5626868 complement(586909..587097) 1 NC_009879.1 COG5346 Predicted membrane protein; hypothetical protein 587097 5626868 A1E_02780 Rickettsia canadensis str. McKiel hypothetical protein YP_001492285.1 586909 R 293613 CDS YP_001492286.1 157803737 5626869 complement(587181..587960) 1 NC_009879.1 biotin--protein ligase 587960 5626869 A1E_02785 Rickettsia canadensis str. McKiel biotin--protein ligase YP_001492286.1 587181 R 293613 CDS YP_001492287.1 157803738 5626870 589016..589189 1 NC_009879.1 COG0340 Biotin-(acetyl-CoA carboxylase) ligase; hypothetical protein 589189 5626870 A1E_02805 Rickettsia canadensis str. McKiel hypothetical protein YP_001492287.1 589016 D 293613 CDS YP_001492288.1 157803739 5626871 complement(589885..590514) 1 NC_009879.1 COG0605 Superoxide dismutase; superoxide dismutase 590514 5626871 A1E_02815 Rickettsia canadensis str. McKiel superoxide dismutase YP_001492288.1 589885 R 293613 CDS YP_001492289.1 157803740 5626448 complement(590605..591909) 1 NC_009879.1 COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 591909 5626448 A1E_02820 Rickettsia canadensis str. McKiel folylpolyglutamate synthase YP_001492289.1 590605 R 293613 CDS YP_001492290.1 157803741 5626449 complement(591911..592471) 1 NC_009879.1 BioY family protein 592471 5626449 A1E_02825 Rickettsia canadensis str. McKiel BioY family protein YP_001492290.1 591911 R 293613 CDS YP_001492291.1 157803742 5626450 592724..593053 1 NC_009879.1 hypothetical protein 593053 5626450 A1E_02830 Rickettsia canadensis str. McKiel hypothetical protein YP_001492291.1 592724 D 293613 CDS YP_001492292.1 157803743 5626451 593121..593249 1 NC_009879.1 COG4285 Uncharacterized conserved protein; hypothetical protein 593249 5626451 A1E_02835 Rickettsia canadensis str. McKiel hypothetical protein YP_001492292.1 593121 D 293613 CDS YP_001492293.1 157803744 5626452 complement(593268..593936) 1 NC_009879.1 COG0625 Glutathione S-transferase; translation initiation factor IF-3 593936 infC 5626452 infC Rickettsia canadensis str. McKiel translation initiation factor IF-3 YP_001492293.1 593268 R 293613 CDS YP_001492294.1 157803745 5626453 594669..597305 1 NC_009879.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 597305 5626453 A1E_02845 Rickettsia canadensis str. McKiel pyruvate phosphate dikinase YP_001492294.1 594669 D 293613 CDS YP_001492295.1 157803746 5626163 complement(597692..597814) 1 NC_009879.1 hypothetical protein 597814 5626163 A1E_02850 Rickettsia canadensis str. McKiel hypothetical protein YP_001492295.1 597692 R 293613 CDS YP_001492296.1 157803747 5626164 complement(597879..597959) 1 NC_009879.1 hypothetical protein 597959 5626164 A1E_02855 Rickettsia canadensis str. McKiel hypothetical protein YP_001492296.1 597879 R 293613 CDS YP_001492297.1 157803748 5626165 complement(598360..598626) 1 NC_009879.1 hypothetical protein 598626 5626165 A1E_02860 Rickettsia canadensis str. McKiel hypothetical protein YP_001492297.1 598360 R 293613 CDS YP_001492298.1 157803749 5626166 599182..600789 1 NC_009879.1 hypothetical protein 600789 5626166 A1E_02865 Rickettsia canadensis str. McKiel hypothetical protein YP_001492298.1 599182 D 293613 CDS YP_001492299.1 157803750 5626167 601306..601401 1 NC_009879.1 hypothetical protein 601401 5626167 A1E_02870 Rickettsia canadensis str. McKiel hypothetical protein YP_001492299.1 601306 D 293613 CDS YP_001492300.1 157803751 5626168 complement(601920..602000) 1 NC_009879.1 hypothetical protein 602000 5626168 A1E_02875 Rickettsia canadensis str. McKiel hypothetical protein YP_001492300.1 601920 R 293613 CDS YP_001492301.1 157803752 5626799 complement(602073..602174) 1 NC_009879.1 COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; hypothetical protein 602174 5626799 A1E_02880 Rickettsia canadensis str. McKiel hypothetical protein YP_001492301.1 602073 R 293613 CDS YP_001492302.1 157803753 5626800 complement(602289..603011) 1 NC_009879.1 COG1496 Uncharacterized conserved protein; hypothetical protein 603011 5626800 A1E_02885 Rickettsia canadensis str. McKiel hypothetical protein YP_001492302.1 602289 R 293613 CDS YP_001492303.1 157803754 5626801 603010..603843 1 NC_009879.1 COG0174 Glutamine synthetase; glutamine synthetase 603843 5626801 A1E_02890 Rickettsia canadensis str. McKiel glutamine synthetase YP_001492303.1 603010 D 293613 CDS YP_001492304.1 157803755 5626802 complement(603991..604818) 1 NC_009879.1 COG1295 Predicted membrane protein; hypothetical protein 604818 5626802 A1E_02895 Rickettsia canadensis str. McKiel hypothetical protein YP_001492304.1 603991 R 293613 CDS YP_001492305.1 157803756 5626803 605440..605832 1 NC_009879.1 transcriptional regulator 605832 5626803 A1E_02900 Rickettsia canadensis str. McKiel transcriptional regulator YP_001492305.1 605440 D 293613 CDS YP_001492306.1 157803757 5626804 complement(606064..608943) 1 NC_009879.1 COG1396 Predicted transcriptional regulators; cell surface antigen 608943 5626804 A1E_02905 Rickettsia canadensis str. McKiel cell surface antigen YP_001492306.1 606064 R 293613 CDS YP_001492307.1 157803758 5626342 complement(609255..610790) 1 NC_009879.1 COG3202 ATP/ADP translocase; pyruvate phosphate dikinase 610790 5626342 A1E_02910 Rickettsia canadensis str. McKiel pyruvate phosphate dikinase YP_001492307.1 609255 R 293613 CDS YP_001492308.1 157803759 5626343 610876..611757 1 NC_009879.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 611757 truB 5626343 truB Rickettsia canadensis str. McKiel tRNA pseudouridine synthase B YP_001492308.1 610876 D 293613 CDS YP_001492309.1 157803760 5626344 611922..612197 1 NC_009879.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 612197 rpsO 5626344 rpsO Rickettsia canadensis str. McKiel 30S ribosomal protein S15 YP_001492309.1 611922 D 293613 CDS YP_001492310.1 157803761 5626345 612464..614707 1 NC_009879.1 COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 614707 5626345 A1E_02925 Rickettsia canadensis str. McKiel polynucleotide phosphorylase/polyadenylase YP_001492310.1 612464 D 293613 CDS YP_001492311.1 157803762 5626346 614847..615806 1 NC_009879.1 COG0794 Predicted sugar phosphate isomerase involved in capsule formation; KpsF protein 615806 5626346 A1E_02930 Rickettsia canadensis str. McKiel KpsF protein YP_001492311.1 614847 D 293613 CDS YP_001492312.1 157803763 5626347 615845..616411 1 NC_009879.1 COG5375 Uncharacterized protein conserved in bacteria; hypothetical protein 616411 5626347 A1E_02935 Rickettsia canadensis str. McKiel hypothetical protein YP_001492312.1 615845 D 293613 CDS YP_001492313.1 157803764 5626123 616377..616814 1 NC_009879.1 COG1934 Uncharacterized protein conserved in bacteria; hypothetical protein 616814 5626123 A1E_02940 Rickettsia canadensis str. McKiel hypothetical protein YP_001492313.1 616377 D 293613 CDS YP_001492314.1 157803765 5626124 616962..617684 1 NC_009879.1 COG1137 ABC-type (unclassified) transport system, ATPase component; ABC transporter ATP-binding protein 617684 5626124 A1E_02945 Rickettsia canadensis str. McKiel ABC transporter ATP-binding protein YP_001492314.1 616962 D 293613 CDS YP_001492315.1 157803766 5626125 617885..619432 1 NC_009879.1 COG1109 Phosphomannomutase; polynucleotide phosphorylase/polyadenylase 619432 5626125 A1E_02950 Rickettsia canadensis str. McKiel polynucleotide phosphorylase/polyadenylase YP_001492315.1 617885 D 293613 CDS YP_001492316.1 157803767 5626126 619429..620406 1 NC_009879.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 620406 miaA 5626126 miaA Rickettsia canadensis str. McKiel tRNA delta(2)-isopentenylpyrophosphate transferase YP_001492316.1 619429 D 293613 CDS YP_001492317.1 157803768 5626127 complement(621037..623904) 1 NC_009879.1 COG0593 ATPase involved in DNA replication initiation; tRNA delta(2)-isopentenylpyrophosphate transferase 623904 miaA 5626127 miaA Rickettsia canadensis str. McKiel tRNA delta(2)-isopentenylpyrophosphate transferase YP_001492317.1 621037 R 293613 CDS YP_001492318.1 157803769 5626128 complement(624006..624980) 1 NC_009879.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 624980 nrdF 5626128 nrdF Rickettsia canadensis str. McKiel ribonucleotide-diphosphate reductase subunit beta YP_001492318.1 624006 R 293613 CDS YP_001492319.1 157803770 5625921 complement(625226..627049) 1 NC_009879.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 627049 5625921 A1E_02970 Rickettsia canadensis str. McKiel ribonucleotide-diphosphate reductase subunit alpha YP_001492319.1 625226 R 293613 CDS YP_001492320.1 157803771 5625922 complement(627244..627342) 1 NC_009879.1 hypothetical protein 627342 5625922 A1E_02975 Rickettsia canadensis str. McKiel hypothetical protein YP_001492320.1 627244 R 293613 CDS YP_001492321.1 157803772 5625923 complement(627951..628109) 1 NC_009879.1 COG0209 Ribonucleotide reductase, alpha subunit; hypothetical protein 628109 5625923 A1E_02980 Rickettsia canadensis str. McKiel hypothetical protein YP_001492321.1 627951 R 293613 CDS YP_001492322.1 157803773 5625924 629165..630178 1 NC_009879.1 COG0492 Thioredoxin reductase; thioredoxin reductase 630178 5625924 A1E_02985 Rickettsia canadensis str. McKiel thioredoxin reductase YP_001492322.1 629165 D 293613 CDS YP_001492323.1 157803774 5625925 630312..631193 1 NC_009879.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 631193 5625925 A1E_02990 Rickettsia canadensis str. McKiel bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001492323.1 630312 D 293613 CDS YP_001492324.1 157803775 5625926 complement(631337..631915) 1 NC_009879.1 sigma(54) modulation protein 631915 5625926 A1E_02995 Rickettsia canadensis str. McKiel sigma(54) modulation protein YP_001492324.1 631337 R 293613 CDS YP_001492325.1 157803776 5626624 complement(633581..633769) 1 NC_009879.1 COG1544 Ribosome-associated protein Y (PSrp-1); hypothetical protein 633769 5626624 A1E_03000 Rickettsia canadensis str. McKiel hypothetical protein YP_001492325.1 633581 R 293613 CDS YP_001492326.1 157803777 5626625 634191..634358 1 NC_009879.1 hypothetical protein 634358 5626625 A1E_03005 Rickettsia canadensis str. McKiel hypothetical protein YP_001492326.1 634191 D 293613 CDS YP_001492327.1 157803778 5626626 634436..634642 1 NC_009879.1 COG5525 Bacteriophage tail assembly protein; hypothetical protein 634642 5626626 A1E_03010 Rickettsia canadensis str. McKiel hypothetical protein YP_001492327.1 634436 D 293613 CDS YP_001492328.1 157803779 5626627 complement(634997..637333) 1 NC_009879.1 COG0466 ATP-dependent Lon protease, bacterial type; ribonucleotide-diphosphate reductase subunit alpha 637333 5626627 A1E_03015 Rickettsia canadensis str. McKiel ribonucleotide-diphosphate reductase subunit alpha YP_001492328.1 634997 R 293613 CDS YP_001492329.1 157803780 5626545 637417..638418 1 NC_009879.1 catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 638418 5626545 A1E_03020 Rickettsia canadensis str. McKiel threonine dehydratase YP_001492329.1 637417 D 293613 CDS YP_001492330.1 157803781 5626546 complement(638415..639782) 1 NC_009879.1 COG1137 ABC-type (unclassified) transport system, ATPase component; hypothetical protein 639782 5626546 A1E_03025 Rickettsia canadensis str. McKiel hypothetical protein YP_001492330.1 638415 R 293613 CDS YP_001492331.1 157803782 5626547 complement(640132..640416) 1 NC_009879.1 COG1038 Pyruvate carboxylase; hypothetical protein 640416 5626547 A1E_03030 Rickettsia canadensis str. McKiel hypothetical protein YP_001492331.1 640132 R 293613 CDS YP_001492332.1 157803783 5626548 complement(640424..642409) 1 NC_009879.1 COG0210 Superfamily I DNA and RNA helicases; DNA helicase II 642409 5626548 A1E_03035 Rickettsia canadensis str. McKiel DNA helicase II YP_001492332.1 640424 R 293613 CDS YP_001492333.1 157803784 5626549 complement(642510..643355) 1 NC_009879.1 glycosyltransferase 643355 5626549 A1E_03040 Rickettsia canadensis str. McKiel glycosyltransferase YP_001492333.1 642510 R 293613 CDS YP_001492334.1 157803785 5626550 complement(643345..643698) 1 NC_009879.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; hypothetical protein 643698 5626550 A1E_03045 Rickettsia canadensis str. McKiel hypothetical protein YP_001492334.1 643345 R 293613 CDS YP_001492335.1 157803786 5626029 644567..644728 1 NC_009879.1 COG1012 NAD-dependent aldehyde dehydrogenases; hypothetical protein 644728 5626029 A1E_03065 Rickettsia canadensis str. McKiel hypothetical protein YP_001492335.1 644567 D 293613 CDS YP_001492336.1 157803787 5626030 complement(646151..646369) 1 NC_009879.1 COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 646369 5626030 A1E_03080 Rickettsia canadensis str. McKiel transposase IS200-family protein YP_001492336.1 646151 R 293613 CDS YP_001492337.1 157803788 5626031 complement(646284..646484) 1 NC_009879.1 transposase IS200-family protein 646484 5626031 A1E_03085 Rickettsia canadensis str. McKiel transposase IS200-family protein YP_001492337.1 646284 R 293613 CDS YP_001492338.1 157803789 5626032 complement(646636..646773) 1 NC_009879.1 hypothetical protein 646773 5626032 A1E_03090 Rickettsia canadensis str. McKiel hypothetical protein YP_001492338.1 646636 R 293613 CDS YP_001492339.1 157803790 5626033 complement(646973..647104) 1 NC_009879.1 COG1943 Transposase and inactivated derivatives; hypothetical protein 647104 5626033 A1E_03095 Rickettsia canadensis str. McKiel hypothetical protein YP_001492339.1 646973 R 293613 CDS YP_001492340.1 157803791 5626034 complement(647384..648316) 1 NC_009879.1 COG0492 Thioredoxin reductase; thioredoxin reductase 648316 5626034 A1E_03100 Rickettsia canadensis str. McKiel thioredoxin reductase YP_001492340.1 647384 R 293613 CDS YP_001492341.1 157803792 5626427 complement(648332..649219) 1 NC_009879.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 649219 5626427 A1E_03105 Rickettsia canadensis str. McKiel hypothetical protein YP_001492341.1 648332 R 293613 CDS YP_001492342.1 157803793 5626428 complement(649277..650206) 1 NC_009879.1 permease 650206 5626428 A1E_03110 Rickettsia canadensis str. McKiel permease YP_001492342.1 649277 R 293613 CDS YP_001492343.1 157803794 5626429 650523..650654 1 NC_009879.1 hypothetical protein 650654 5626429 A1E_03115 Rickettsia canadensis str. McKiel hypothetical protein YP_001492343.1 650523 D 293613 CDS YP_001492344.1 157803795 5626430 651146..651343 1 NC_009879.1 COG0679 Predicted permeases; hypothetical protein 651343 5626430 A1E_03120 Rickettsia canadensis str. McKiel hypothetical protein YP_001492344.1 651146 D 293613 CDS YP_001492345.1 157803796 5626431 complement(651711..653396) 1 NC_009879.1 COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; threonine dehydratase 653396 5626431 A1E_03125 Rickettsia canadensis str. McKiel threonine dehydratase YP_001492345.1 651711 R 293613 CDS YP_001492346.1 157803797 5626432 653482..654249 1 NC_009879.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 654249 ppnK 5626432 ppnK Rickettsia canadensis str. McKiel inorganic polyphosphate/ATP-NAD kinase YP_001492346.1 653482 D 293613 CDS YP_001492347.1 157803798 5626701 654603..654791 1 NC_009879.1 hypothetical protein 654791 5626701 A1E_03135 Rickettsia canadensis str. McKiel hypothetical protein YP_001492347.1 654603 D 293613 CDS YP_001492348.1 157803799 5626702 655103..655333 1 NC_009879.1 hypothetical protein 655333 5626702 A1E_03140 Rickettsia canadensis str. McKiel hypothetical protein YP_001492348.1 655103 D 293613 CDS YP_001492349.1 157803800 5626703 655891..656028 1 NC_009879.1 COG0061 Predicted sugar kinase; hypothetical protein 656028 5626703 A1E_03145 Rickettsia canadensis str. McKiel hypothetical protein YP_001492349.1 655891 D 293613 CDS YP_001492350.1 157803801 5626704 complement(656115..656714) 1 NC_009879.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 656714 recR 5626704 recR Rickettsia canadensis str. McKiel recombination protein RecR YP_001492350.1 656115 R 293613 CDS YP_001492351.1 157803802 5626705 complement(656723..657241) 1 NC_009879.1 COG1714 Predicted membrane protein/domain; hypothetical protein 657241 5626705 A1E_03155 Rickettsia canadensis str. McKiel hypothetical protein YP_001492351.1 656723 R 293613 CDS YP_001492352.1 157803803 5626706 657479..657907 1 NC_009879.1 COG1238 Predicted membrane protein; hypothetical protein 657907 5626706 A1E_03160 Rickettsia canadensis str. McKiel hypothetical protein YP_001492352.1 657479 D 293613 CDS YP_001492353.1 157803804 5626770 657871..658305 1 NC_009879.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 658305 rbfA 5626770 rbfA Rickettsia canadensis str. McKiel ribosome-binding factor A YP_001492353.1 657871 D 293613 CDS YP_001492354.1 157803805 5626771 658634..659269 1 NC_009879.1 COG4395 Uncharacterized protein conserved in bacteria; hypothetical protein 659269 5626771 A1E_03170 Rickettsia canadensis str. McKiel hypothetical protein YP_001492354.1 658634 D 293613 CDS YP_001492355.1 157803806 5626772 659445..661484 1 NC_009879.1 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; acylamino-acid-releasing enzyme 661484 5626772 A1E_03175 Rickettsia canadensis str. McKiel acylamino-acid-releasing enzyme YP_001492355.1 659445 D 293613 CDS YP_001492356.1 157803807 5626773 661660..662820 1 NC_009879.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 662820 sucC 5626773 sucC Rickettsia canadensis str. McKiel succinyl-CoA synthetase subunit beta YP_001492356.1 661660 D 293613 CDS YP_001492357.1 157803808 5626774 663016..663894 1 NC_009879.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 663894 5626774 A1E_03185 Rickettsia canadensis str. McKiel succinyl-CoA synthetase subunit alpha YP_001492357.1 663016 D 293613 CDS YP_001492358.1 157803809 5626775 complement(664171..664239) 1 NC_009879.1 hypothetical protein 664239 5626775 A1E_03190 Rickettsia canadensis str. McKiel hypothetical protein YP_001492358.1 664171 R 293613 CDS YP_001492359.1 157803810 5626680 complement(664232..664342) 1 NC_009879.1 COG0074 Succinyl-CoA synthetase, alpha subunit; hypothetical protein 664342 5626680 A1E_03195 Rickettsia canadensis str. McKiel hypothetical protein YP_001492359.1 664232 R 293613 CDS YP_001492360.1 157803811 5626681 complement(664600..665400) 1 NC_009879.1 COG1651 Protein-disulfide isomerase; Thiol:disulfide interchange protein DsbA 665400 5626681 A1E_03200 Rickettsia canadensis str. McKiel Thiol:disulfide interchange protein DsbA YP_001492360.1 664600 R 293613 CDS YP_001492361.1 157803812 5626682 complement(665439..665897) 1 NC_009879.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 665897 smpB 5626682 smpB Rickettsia canadensis str. McKiel SsrA-binding protein YP_001492361.1 665439 R 293613 CDS YP_001492362.1 157803813 5626683 complement(665894..666778) 1 NC_009879.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 666778 5626683 A1E_03210 Rickettsia canadensis str. McKiel dihydrodipicolinate synthase YP_001492362.1 665894 R 293613 CDS YP_001492363.1 157803814 5626684 complement(666900..667772) 1 NC_009879.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 667772 5626684 A1E_03215 Rickettsia canadensis str. McKiel branched-chain amino acid aminotransferase YP_001492363.1 666900 R 293613 CDS YP_001492364.1 157803815 5626685 668028..668708 1 NC_009879.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; petR protein 668708 5626685 A1E_03220 Rickettsia canadensis str. McKiel petR protein YP_001492364.1 668028 D 293613 CDS YP_001492365.1 157803816 5626191 668740..670146 1 NC_009879.1 osmolarity sensor protein EnvZ 670146 5626191 A1E_03225 Rickettsia canadensis str. McKiel osmolarity sensor protein EnvZ YP_001492365.1 668740 D 293613 CDS YP_001492366.1 157803817 5626192 670169..670849 1 NC_009879.1 COG0020 Undecaprenyl pyrophosphate synthase; undecaprenyl pyrophosphate synthetase 670849 5626192 A1E_03230 Rickettsia canadensis str. McKiel undecaprenyl pyrophosphate synthetase YP_001492366.1 670169 D 293613 CDS YP_001492367.1 157803818 5626193 670809..671498 1 NC_009879.1 COG0575 CDP-diglyceride synthetase; phosphatidate cytidylyltransferase 671498 5626193 A1E_03235 Rickettsia canadensis str. McKiel phosphatidate cytidylyltransferase YP_001492367.1 670809 D 293613 CDS YP_001492368.1 157803819 5626194 671688..672023 1 NC_009879.1 COG2919 Septum formation initiator; hypothetical protein 672023 5626194 A1E_03240 Rickettsia canadensis str. McKiel hypothetical protein YP_001492368.1 671688 D 293613 CDS YP_001492369.1 157803820 5626195 672122..672733 1 NC_009879.1 COG0349 Ribonuclease D; ribonuclease D 672733 5626195 A1E_03245 Rickettsia canadensis str. McKiel ribonuclease D YP_001492369.1 672122 D 293613 CDS YP_001492370.1 157803821 5626196 complement(673305..675809) 1 NC_009879.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 675809 leuS 5626196 leuS Rickettsia canadensis str. McKiel leucyl-tRNA synthetase YP_001492370.1 673305 R 293613 CDS YP_001492371.1 157803822 5626782 complement(675990..676493) 1 NC_009879.1 COG0495 Leucyl-tRNA synthetase; hypothetical protein 676493 5626782 A1E_03255 Rickettsia canadensis str. McKiel hypothetical protein YP_001492371.1 675990 R 293613 CDS YP_001492372.1 157803823 5626783 complement(676625..677764) 1 NC_009879.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 677764 5626783 A1E_03260 Rickettsia canadensis str. McKiel DNA polymerase III subunit beta YP_001492372.1 676625 R 293613 CDS YP_001492373.1 157803824 5626784 complement(677769..680282) 1 NC_009879.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 680282 pheT 5626784 pheT Rickettsia canadensis str. McKiel phenylalanyl-tRNA synthetase subunit beta YP_001492373.1 677769 R 293613 CDS YP_001492374.1 157803825 5626785 complement(680279..681328) 1 NC_009879.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 681328 pheS 5626785 pheS Rickettsia canadensis str. McKiel phenylalanyl-tRNA synthetase subunit alpha YP_001492374.1 680279 R 293613 CDS YP_001492375.1 157803826 5626786 complement(681364..682632) 1 NC_009879.1 COG0621 2-methylthioadenine synthetase; MiaB-like tRNA modifying enzyme 682632 5626786 A1E_03275 Rickettsia canadensis str. McKiel MiaB-like tRNA modifying enzyme YP_001492375.1 681364 R 293613 CDS YP_001492376.1 157803827 5626787 complement(682625..683434) 1 NC_009879.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 683434 dapF 5626787 dapF Rickettsia canadensis str. McKiel diaminopimelate epimerase YP_001492376.1 682625 R 293613 CDS YP_001492377.1 157803828 5625814 684072..684275 1 NC_009879.1 hypothetical protein 684275 5625814 A1E_03285 Rickettsia canadensis str. McKiel hypothetical protein YP_001492377.1 684072 D 293613 CDS YP_001492379.1 157803830 5625816 684434..685597 1 NC_009879.1 COG0438 Glycosyltransferase; capM protein 685597 5625816 A1E_03295 Rickettsia canadensis str. McKiel capM protein YP_001492379.1 684434 D 293613 CDS YP_001492380.1 157803831 5625817 685668..685820 1 NC_009879.1 RND efflux system, outer membrane protein 685820 5625817 A1E_03300 Rickettsia canadensis str. McKiel RND efflux system, outer membrane protein YP_001492380.1 685668 D 293613 CDS YP_001492381.1 157803832 5625818 complement(686575..687234) 1 NC_009879.1 COG1538 Outer membrane protein; hypothetical protein 687234 5625818 A1E_03305 Rickettsia canadensis str. McKiel hypothetical protein YP_001492381.1 686575 R 293613 CDS YP_001492382.1 157803833 5625819 complement(687564..688628) 1 NC_009879.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 688628 murG 5625819 murG Rickettsia canadensis str. McKiel undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001492382.1 687564 R 293613 CDS YP_001492383.1 157803834 5626486 complement(688625..689764) 1 NC_009879.1 cell division protein FtsW 689764 5626486 A1E_03315 Rickettsia canadensis str. McKiel cell division protein FtsW YP_001492383.1 688625 R 293613 CDS YP_001492384.1 157803835 5626487 689956..690534 1 NC_009879.1 hypothetical protein 690534 5626487 A1E_03320 Rickettsia canadensis str. McKiel hypothetical protein YP_001492384.1 689956 D 293613 CDS YP_001492385.1 157803836 5626488 690832..691035 1 NC_009879.1 COG0772 Bacterial cell division membrane protein; hypothetical protein 691035 5626488 A1E_03325 Rickettsia canadensis str. McKiel hypothetical protein YP_001492385.1 690832 D 293613 CDS YP_001492386.1 157803837 5626489 complement(691042..692409) 1 NC_009879.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 692409 murD 5626489 murD Rickettsia canadensis str. McKiel UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001492386.1 691042 R 293613 CDS YP_001492387.1 157803838 5626490 complement(692556..692801) 1 NC_009879.1 COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; hypothetical protein 692801 5626490 A1E_03335 Rickettsia canadensis str. McKiel hypothetical protein YP_001492387.1 692556 R 293613 CDS YP_001492388.1 157803839 5626491 complement(692822..693412) 1 NC_009879.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 693412 lspA 5626491 lspA Rickettsia canadensis str. McKiel lipoprotein signal peptidase YP_001492388.1 692822 R 293613 CDS YP_001492389.1 157803840 5625897 complement(693708..695081) 1 NC_009879.1 COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 695081 5625897 A1E_03345 Rickettsia canadensis str. McKiel hypothetical protein YP_001492389.1 693708 R 293613 CDS YP_001492390.1 157803841 5625898 695834..696625 1 NC_009879.1 COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome c oxidase polypeptide II 696625 5625898 A1E_03350 Rickettsia canadensis str. McKiel cytochrome c oxidase polypeptide II YP_001492390.1 695834 D 293613 CDS YP_001492391.1 157803842 5625899 696664..697047 1 NC_009879.1 COG0110 Acetyltransferase (isoleucine patch superfamily); virginiamycin A acetyltransferase 697047 5625899 A1E_03355 Rickettsia canadensis str. McKiel virginiamycin A acetyltransferase YP_001492391.1 696664 D 293613 CDS YP_001492392.1 157803843 5625900 697067..698665 1 NC_009879.1 COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome c oxidase polypeptide I 698665 5625900 A1E_03360 Rickettsia canadensis str. McKiel cytochrome c oxidase polypeptide I YP_001492392.1 697067 D 293613 CDS YP_001492393.1 157803844 5625901 698892..699629 1 NC_009879.1 COG2071 Predicted glutamine amidotransferases; hypothetical protein 699629 5625901 A1E_03365 Rickettsia canadensis str. McKiel hypothetical protein YP_001492393.1 698892 D 293613 CDS YP_001492394.1 157803845 5625902 700089..702875 1 NC_009879.1 COG2887 RecB family exonuclease; hypothetical protein 702875 5625902 A1E_03370 Rickettsia canadensis str. McKiel hypothetical protein YP_001492394.1 700089 D 293613 CDS YP_001492395.1 157803846 5625841 complement(702858..703805) 1 NC_009879.1 microcin C7 self-immunity protein 703805 5625841 A1E_03375 Rickettsia canadensis str. McKiel microcin C7 self-immunity protein YP_001492395.1 702858 R 293613 CDS YP_001492396.1 157803847 5625842 complement(704098..704253) 1 NC_009879.1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; hypothetical protein 704253 5625842 A1E_03380 Rickettsia canadensis str. McKiel hypothetical protein YP_001492396.1 704098 R 293613 CDS YP_001492397.1 157803848 5625843 complement(705230..707185) 1 NC_009879.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); soluble lytic murein transglycosylase precursor 707185 5625843 A1E_03385 Rickettsia canadensis str. McKiel soluble lytic murein transglycosylase precursor YP_001492397.1 705230 R 293613 CDS YP_001492398.1 157803849 5625844 complement(707337..707783) 1 NC_009879.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 707783 dut 5625844 dut Rickettsia canadensis str. McKiel deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001492398.1 707337 R 293613 CDS YP_001492399.1 157803850 5625845 complement(707786..708700) 1 NC_009879.1 COG0616 Periplasmic serine proteases (ClpP class); protease sohB 708700 5625845 A1E_03395 Rickettsia canadensis str. McKiel protease sohB YP_001492399.1 707786 R 293613 CDS YP_001492400.1 157803851 5625846 complement(708700..709368) 1 NC_009879.1 COG0526 Thiol-disulfide isomerase and thioredoxins; Thiol:disulfide interchange protein TlpA 709368 5625846 A1E_03400 Rickettsia canadensis str. McKiel Thiol:disulfide interchange protein TlpA YP_001492400.1 708700 R 293613 CDS YP_001492401.1 157803852 5626454 complement(709630..710256) 1 NC_009879.1 COG3485 Protocatechuate 3,4-dioxygenase beta subunit; protocatechuate-3,4-dioxygenase, beta subunit 710256 5626454 A1E_03405 Rickettsia canadensis str. McKiel protocatechuate-3,4-dioxygenase, beta subunit YP_001492401.1 709630 R 293613 CDS YP_001492402.1 157803853 5626455 710397..711392 1 NC_009879.1 hypothetical protein 711392 5626455 A1E_03410 Rickettsia canadensis str. McKiel hypothetical protein YP_001492402.1 710397 D 293613 CDS YP_001492403.1 157803854 5626456 complement(711440..711613) 1 NC_009879.1 hypothetical protein 711613 5626456 A1E_03415 Rickettsia canadensis str. McKiel hypothetical protein YP_001492403.1 711440 R 293613 CDS YP_001492404.1 157803855 5626457 711696..712073 1 NC_009879.1 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; hypothetical protein 712073 5626457 A1E_03420 Rickettsia canadensis str. McKiel hypothetical protein YP_001492404.1 711696 D 293613 CDS YP_001492405.1 157803856 5626458 712082..712921 1 NC_009879.1 COG0672 High-affinity Fe2+/Pb2+ permease; FTR1 family protein 712921 5626458 A1E_03425 Rickettsia canadensis str. McKiel FTR1 family protein YP_001492405.1 712082 D 293613 CDS YP_001492406.1 157803857 5626459 712961..713503 1 NC_009879.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 713503 5626459 A1E_03430 Rickettsia canadensis str. McKiel intracellular septation protein A YP_001492406.1 712961 D 293613 CDS YP_001492407.1 157803858 5626151 713500..714279 1 NC_009879.1 COG2823 Predicted periplasmic or secreted lipoprotein; hypothetical protein 714279 5626151 A1E_03435 Rickettsia canadensis str. McKiel hypothetical protein YP_001492407.1 713500 D 293613 CDS YP_001492408.1 157803859 5626152 714263..714949 1 NC_009879.1 COG0797 Lipoproteins; rare lipoprotein A precursor 714949 5626152 A1E_03440 Rickettsia canadensis str. McKiel rare lipoprotein A precursor YP_001492408.1 714263 D 293613 CDS YP_001492409.1 157803860 5626153 complement(715076..715996) 1 NC_009879.1 COG1686 D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein DacF precursor 715996 5626153 A1E_03445 Rickettsia canadensis str. McKiel penicillin-binding protein DacF precursor YP_001492409.1 715076 R 293613 CDS YP_001492410.1 157803861 5626154 complement(716153..717397) 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; AmpG protein 717397 5626154 A1E_03450 Rickettsia canadensis str. McKiel AmpG protein YP_001492410.1 716153 R 293613 CDS YP_001492411.1 157803862 5626155 complement(717572..719335) 1 NC_009879.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein 719335 5626155 A1E_03455 Rickettsia canadensis str. McKiel multidrug resistance protein YP_001492411.1 717572 R 293613 CDS YP_001492412.1 157803863 5626156 complement(719328..720356) 1 NC_009879.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 720356 ruvB 5626156 ruvB Rickettsia canadensis str. McKiel Holliday junction DNA helicase RuvB YP_001492412.1 719328 R 293613 CDS YP_001492413.1 157803864 5626057 complement(720946..721146) 1 NC_009879.1 hypothetical protein 721146 5626057 A1E_03465 Rickettsia canadensis str. McKiel hypothetical protein YP_001492413.1 720946 R 293613 CDS YP_001492414.1 157803865 5626058 complement(721433..721723) 1 NC_009879.1 COG2255 Holliday junction resolvasome, helicase subunit; hypothetical protein 721723 5626058 A1E_03470 Rickettsia canadensis str. McKiel hypothetical protein YP_001492414.1 721433 R 293613 CDS YP_001492415.1 157803866 5626059 complement(721854..722468) 1 NC_009879.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 722468 ruvA 5626059 ruvA Rickettsia canadensis str. McKiel Holliday junction DNA helicase RuvA YP_001492415.1 721854 R 293613 CDS YP_001492416.1 157803867 5626060 complement(722470..722718) 1 NC_009879.1 hypothetical protein 722718 5626060 A1E_03480 Rickettsia canadensis str. McKiel hypothetical protein YP_001492416.1 722470 R 293613 CDS YP_001492417.1 157803868 5626061 complement(722957..723187) 1 NC_009879.1 COG0632 Holliday junction resolvasome, DNA-binding subunit; hypothetical protein 723187 5626061 A1E_03485 Rickettsia canadensis str. McKiel hypothetical protein YP_001492417.1 722957 R 293613 CDS YP_001492418.1 157803869 5626062 complement(723366..723554) 1 NC_009879.1 COG3177 Uncharacterized conserved protein; hypothetical protein 723554 5626062 A1E_03490 Rickettsia canadensis str. McKiel hypothetical protein YP_001492418.1 723366 R 293613 CDS YP_001492419.1 157803870 5626140 complement(723720..725036) 1 NC_009879.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 725036 5626140 A1E_03495 Rickettsia canadensis str. McKiel prolyl-tRNA synthetase YP_001492419.1 723720 R 293613 CDS YP_001492420.1 157803871 5626141 complement(725127..725786) 1 NC_009879.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 725786 folE 5626141 folE Rickettsia canadensis str. McKiel GTP cyclohydrolase I YP_001492420.1 725127 R 293613 CDS YP_001492421.1 157803872 5626142 complement(725919..726935) 1 NC_009879.1 hypothetical protein 726935 5626142 A1E_03505 Rickettsia canadensis str. McKiel hypothetical protein YP_001492421.1 725919 R 293613 CDS YP_001492422.1 157803873 5626143 complement(727506..727622) 1 NC_009879.1 COG0302 GTP cyclohydrolase I; hypothetical protein 727622 5626143 A1E_03510 Rickettsia canadensis str. McKiel hypothetical protein YP_001492422.1 727506 R 293613 CDS YP_001492423.1 157803874 5625977 728159..728893 1 NC_009879.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 728893 5625977 A1E_03515 Rickettsia canadensis str. McKiel 3-deoxy-manno-octulosonate cytidylyltransferase YP_001492423.1 728159 D 293613 CDS YP_001492424.1 157803875 5625978 728871..729038 1 NC_009879.1 COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; hypothetical protein 729038 5625978 A1E_03520 Rickettsia canadensis str. McKiel hypothetical protein YP_001492424.1 728871 D 293613 CDS YP_001492425.1 157803876 5625979 730770..732293 1 NC_009879.1 COG3202 ATP/ADP translocase; ADP,ATP carrier protein 732293 5625979 A1E_03535 Rickettsia canadensis str. McKiel ADP,ATP carrier protein YP_001492425.1 730770 D 293613 CDS YP_001492426.1 157803877 5625980 732388..733332 1 NC_009879.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 733332 5625980 A1E_03540 Rickettsia canadensis str. McKiel malate dehydrogenase YP_001492426.1 732388 D 293613 CDS YP_001492427.1 157803878 5626134 734040..734252 1 NC_009879.1 hypothetical protein 734252 5626134 A1E_03545 Rickettsia canadensis str. McKiel hypothetical protein YP_001492427.1 734040 D 293613 CDS YP_001492428.1 157803879 5626135 734623..734865 1 NC_009879.1 hypothetical protein 734865 5626135 A1E_03550 Rickettsia canadensis str. McKiel hypothetical protein YP_001492428.1 734623 D 293613 CDS YP_001492429.1 157803880 5626136 735025..735234 1 NC_009879.1 hypothetical protein 735234 5626136 A1E_03555 Rickettsia canadensis str. McKiel hypothetical protein YP_001492429.1 735025 D 293613 CDS YP_001492430.1 157803881 5626137 735322..735426 1 NC_009879.1 hypothetical protein 735426 5626137 A1E_03560 Rickettsia canadensis str. McKiel hypothetical protein YP_001492430.1 735322 D 293613 CDS YP_001492431.1 157803882 5626138 735444..735584 1 NC_009879.1 hypothetical protein 735584 5626138 A1E_03565 Rickettsia canadensis str. McKiel hypothetical protein YP_001492431.1 735444 D 293613 CDS YP_001492432.1 157803883 5626139 735933..736106 1 NC_009879.1 COG0039 Malate/lactate dehydrogenases; hypothetical protein 736106 5626139 A1E_03570 Rickettsia canadensis str. McKiel hypothetical protein YP_001492432.1 735933 D 293613 CDS YP_001492433.1 157803884 5626637 complement(736140..737468) 1 NC_009879.1 proline/betaine transporter 737468 5626637 A1E_03575 Rickettsia canadensis str. McKiel proline/betaine transporter YP_001492433.1 736140 R 293613 CDS YP_001492434.1 157803885 5626638 complement(737776..737868) 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 737868 5626638 A1E_03580 Rickettsia canadensis str. McKiel hypothetical protein YP_001492434.1 737776 R 293613 CDS YP_001492435.1 157803886 5626639 complement(738097..740397) 1 NC_009879.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 740397 5626639 A1E_03585 Rickettsia canadensis str. McKiel malic enzyme YP_001492435.1 738097 R 293613 CDS YP_001492436.1 157803887 5626640 complement(740506..741447) 1 NC_009879.1 COG0679 Predicted permeases; permease 741447 5626640 A1E_03590 Rickettsia canadensis str. McKiel permease YP_001492436.1 740506 R 293613 CDS YP_001492437.1 157803888 5626641 complement(741514..743082) 1 NC_009879.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 743082 lysK 5626641 lysK Rickettsia canadensis str. McKiel lysyl-tRNA synthetase YP_001492437.1 741514 R 293613 CDS YP_001492438.1 157803889 5626642 743307..743825 1 NC_009879.1 hypothetical protein 743825 5626642 A1E_03600 Rickettsia canadensis str. McKiel hypothetical protein YP_001492438.1 743307 D 293613 CDS YP_001492439.1 157803890 5625960 complement(743932..744102) 1 NC_009879.1 ABC transporter permease protein 744102 5625960 A1E_03605 Rickettsia canadensis str. McKiel ABC transporter permease protein YP_001492439.1 743932 R 293613 CDS YP_001492440.1 157803891 5625961 complement(745759..746547) 1 NC_009879.1 COG3023 Negative regulator of beta-lactamase expression; hypothetical protein 746547 5625961 A1E_03620 Rickettsia canadensis str. McKiel hypothetical protein YP_001492440.1 745759 R 293613 CDS YP_001492441.1 157803892 5625962 complement(746785..746979) 1 NC_009879.1 COG1396 Predicted transcriptional regulators; hypothetical protein 746979 5625962 A1E_03625 Rickettsia canadensis str. McKiel hypothetical protein YP_001492441.1 746785 R 293613 CDS YP_001492442.1 157803893 5625963 complement(747157..748647) 1 NC_009879.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 748647 lnt 5625963 lnt Rickettsia canadensis str. McKiel apolipoprotein N-acyltransferase YP_001492442.1 747157 R 293613 CDS YP_001492443.1 157803894 5625964 748738..749520 1 NC_009879.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 749520 5625964 A1E_03635 Rickettsia canadensis str. McKiel enoyl-(acyl carrier protein) reductase YP_001492443.1 748738 D 293613 CDS YP_001492444.1 157803895 5625965 complement(749781..749915) 1 NC_009879.1 hypothetical protein 749915 5625965 A1E_03640 Rickettsia canadensis str. McKiel hypothetical protein YP_001492444.1 749781 R 293613 CDS YP_001492445.1 157803896 5625887 complement(750599..750694) 1 NC_009879.1 hypothetical protein 750694 5625887 A1E_03645 Rickettsia canadensis str. McKiel hypothetical protein YP_001492445.1 750599 R 293613 CDS YP_001492446.1 157803897 5625888 complement(750898..751812) 1 NC_009879.1 COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); hypothetical protein 751812 5625888 A1E_03650 Rickettsia canadensis str. McKiel hypothetical protein YP_001492446.1 750898 R 293613 CDS YP_001492447.1 157803898 5625889 complement(751881..752807) 1 NC_009879.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 752807 xerD 5625889 xerD Rickettsia canadensis str. McKiel site-specific tyrosine recombinase XerD YP_001492447.1 751881 R 293613 CDS YP_001492448.1 157803899 5625891 754456..754929 1 NC_009879.1 COG4765 Uncharacterized protein conserved in bacteria; hypothetical protein 754929 5625891 A1E_03660 Rickettsia canadensis str. McKiel hypothetical protein YP_001492448.1 754456 D 293613 CDS YP_001492449.1 157803900 5626174 754930..756177 1 NC_009879.1 COG3307 Lipid A core - O-antigen ligase and related enzymes; hypothetical protein 756177 5626174 A1E_03665 Rickettsia canadensis str. McKiel hypothetical protein YP_001492449.1 754930 D 293613 CDS YP_001492450.1 157803901 5626175 756328..756699 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 756699 5626175 A1E_03670 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit A YP_001492450.1 756328 D 293613 CDS YP_001492451.1 157803902 5626176 756704..757228 1 NC_009879.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 757228 5626176 A1E_03675 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit B YP_001492451.1 756704 D 293613 CDS YP_001492452.1 157803903 5626177 757206..757796 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 757796 5626177 A1E_03680 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit C YP_001492452.1 757206 D 293613 CDS YP_001492453.1 157803904 5626178 757959..758084 1 NC_009879.1 COG2827 Predicted endonuclease containing a URI domain; hypothetical protein 758084 5626178 A1E_03685 Rickettsia canadensis str. McKiel hypothetical protein YP_001492453.1 757959 D 293613 CDS YP_001492454.1 157803905 5626179 758161..759348 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 759348 5626179 A1E_03690 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit D YP_001492454.1 758161 D 293613 CDS YP_001492455.1 157803906 5625903 759367..759582 1 NC_009879.1 COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; hypothetical protein 759582 5625903 A1E_03695 Rickettsia canadensis str. McKiel hypothetical protein YP_001492455.1 759367 D 293613 CDS YP_001492456.1 157803907 5625904 759697..760200 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 760200 5625904 A1E_03700 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit E YP_001492456.1 759697 D 293613 CDS YP_001492457.1 157803908 5625905 760193..760459 1 NC_009879.1 COG0759 Uncharacterized conserved protein; hypothetical protein 760459 5625905 A1E_03705 Rickettsia canadensis str. McKiel hypothetical protein YP_001492457.1 760193 D 293613 CDS YP_001492458.1 157803909 5625906 760593..761135 1 NC_009879.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 761135 5625906 A1E_03710 Rickettsia canadensis str. McKiel 3-methyladenine DNA glycosylase YP_001492458.1 760593 D 293613 CDS YP_001492459.1 157803910 5625907 complement(762035..762277) 1 NC_009879.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 762277 5625907 A1E_03715 Rickettsia canadensis str. McKiel exodeoxyribonuclease VII small subunit YP_001492459.1 762035 R 293613 CDS YP_001492460.1 157803911 5625908 complement(762292..764922) 1 NC_009879.1 COG1722 Exonuclease VII small subunit; hypothetical protein 764922 5625908 A1E_03720 Rickettsia canadensis str. McKiel hypothetical protein YP_001492460.1 762292 R 293613 CDS YP_001492461.1 157803912 5626501 764991..765488 1 NC_009879.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 765488 rimM 5626501 rimM Rickettsia canadensis str. McKiel 16S rRNA-processing protein RimM YP_001492461.1 764991 D 293613 CDS YP_001492462.1 157803913 5626502 complement(768727..768822) 1 NC_009879.1 hypothetical protein 768822 5626502 A1E_03740 Rickettsia canadensis str. McKiel hypothetical protein YP_001492462.1 768727 R 293613 CDS YP_001492463.1 157803914 5626503 769342..769527 1 NC_009879.1 hypothetical protein 769527 5626503 A1E_03745 Rickettsia canadensis str. McKiel hypothetical protein YP_001492463.1 769342 D 293613 CDS YP_001492464.1 157803915 5626504 complement(769712..770056) 1 NC_009879.1 COG0806 RimM protein, required for 16S rRNA processing; hypothetical protein 770056 5626504 A1E_03750 Rickettsia canadensis str. McKiel hypothetical protein YP_001492464.1 769712 R 293613 CDS YP_001492465.1 157803916 5626505 complement(770730..771653) 1 NC_009879.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 771653 5626505 A1E_03755 Rickettsia canadensis str. McKiel protoheme IX farnesyltransferase YP_001492465.1 770730 R 293613 CDS YP_001492466.1 157803917 5626506 771771..772388 1 NC_009879.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 772388 rpsD 5626506 rpsD Rickettsia canadensis str. McKiel 30S ribosomal protein S4 YP_001492466.1 771771 D 293613 CDS YP_001492467.1 157803918 5625992 complement(772712..773890) 1 NC_009879.1 COG0438 Glycosyltransferase; glycosyltransferase 773890 5625992 A1E_03765 Rickettsia canadensis str. McKiel glycosyltransferase YP_001492467.1 772712 R 293613 CDS YP_001492468.1 157803919 5625993 774024..774683 1 NC_009879.1 hydrolase or acyltransferase 774683 5625993 A1E_03770 Rickettsia canadensis str. McKiel hydrolase or acyltransferase YP_001492468.1 774024 D 293613 CDS YP_001492469.1 157803920 5625994 774911..775675 1 NC_009879.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 775675 5625994 A1E_03775 Rickettsia canadensis str. McKiel hypothetical protein YP_001492469.1 774911 D 293613 CDS YP_001492470.1 157803921 5625995 775680..776816 1 NC_009879.1 COG0845 Membrane-fusion protein; RND family efflux transporter MFP subunit 776816 5625995 A1E_03780 Rickettsia canadensis str. McKiel RND family efflux transporter MFP subunit YP_001492470.1 775680 D 293613 CDS YP_001492471.1 157803922 5625996 complement(776818..777858) 1 NC_009879.1 COG0438 Glycosyltransferase; hypothetical protein 777858 5625996 A1E_03785 Rickettsia canadensis str. McKiel hypothetical protein YP_001492471.1 776818 R 293613 CDS YP_001492472.1 157803923 5625997 complement(777828..778796) 1 NC_009879.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; minor teichoic acids biosynthesis protein ggab (ggab) 778796 5625997 A1E_03790 Rickettsia canadensis str. McKiel minor teichoic acids biosynthesis protein ggab (ggab) YP_001492472.1 777828 R 293613 CDS YP_001492473.1 157803924 5626306 complement(778797..779996) 1 NC_009879.1 COG0438 Glycosyltransferase; glycosyltransferase 779996 5626306 A1E_03795 Rickettsia canadensis str. McKiel glycosyltransferase YP_001492473.1 778797 R 293613 CDS YP_001492474.1 157803925 5626307 complement(779993..781216) 1 NC_009879.1 COG0438 Glycosyltransferase; glycosyltransferase 781216 5626307 A1E_03800 Rickettsia canadensis str. McKiel glycosyltransferase YP_001492474.1 779993 R 293613 CDS YP_001492475.1 157803926 5626308 complement(781249..782391) 1 NC_009879.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 782391 5626308 A1E_03805 Rickettsia canadensis str. McKiel hypothetical protein YP_001492475.1 781249 R 293613 CDS YP_001492476.1 157803927 5626309 complement(782388..783518) 1 NC_009879.1 COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 783518 5626309 A1E_03810 Rickettsia canadensis str. McKiel UDP-N-acetylglucosamine 2-epimerase YP_001492476.1 782388 R 293613 CDS YP_001492477.1 157803928 5626310 complement(783511..784536) 1 NC_009879.1 COG1086 Predicted nucleoside-diphosphate sugar epimerases; capD protein 784536 5626310 A1E_03815 Rickettsia canadensis str. McKiel capD protein YP_001492477.1 783511 R 293613 CDS YP_001492478.1 157803929 5626311 complement(784746..785600) 1 NC_009879.1 putative dTDP-4-dehydrorhamnose reductase 785600 5626311 A1E_03820 Rickettsia canadensis str. McKiel putative dTDP-4-dehydrorhamnose reductase YP_001492478.1 784746 R 293613 CDS YP_001492479.1 157803930 5626612 785686..785820 1 NC_009879.1 COG1091 dTDP-4-dehydrorhamnose reductase; hypothetical protein 785820 5626612 A1E_03825 Rickettsia canadensis str. McKiel hypothetical protein YP_001492479.1 785686 D 293613 CDS YP_001492480.1 157803931 5626613 complement(786157..786621) 1 NC_009879.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 786621 5626613 A1E_03830 Rickettsia canadensis str. McKiel Holliday junction resolvase-like protein YP_001492480.1 786157 R 293613 CDS YP_001492481.1 157803932 5626614 786620..788224 1 NC_009879.1 hypothetical protein 788224 5626614 A1E_03835 Rickettsia canadensis str. McKiel hypothetical protein YP_001492481.1 786620 D 293613 CDS YP_001492482.1 157803933 5626615 788315..788419 1 NC_009879.1 COG2194 Predicted membrane-associated, metal-dependent hydrolase; hypothetical protein 788419 5626615 A1E_03840 Rickettsia canadensis str. McKiel hypothetical protein YP_001492482.1 788315 D 293613 CDS YP_001492483.1 157803934 5626616 788594..789529 1 NC_009879.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 789529 5626616 A1E_03845 Rickettsia canadensis str. McKiel hypothetical protein YP_001492483.1 788594 D 293613 CDS YP_001492484.1 157803935 5626617 789611..790213 1 NC_009879.1 COG0450 Peroxiredoxin; thioredoxin peroxidase 1 790213 5626617 A1E_03850 Rickettsia canadensis str. McKiel thioredoxin peroxidase 1 YP_001492484.1 789611 D 293613 CDS YP_001492485.1 157803936 5626063 791189..793522 1 NC_009879.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 793522 5626063 A1E_03865 Rickettsia canadensis str. McKiel DNA topoisomerase I YP_001492485.1 791189 D 293613 CDS YP_001492486.1 157803937 5626064 793687..795024 1 NC_009879.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 795024 gltX 5626064 gltX Rickettsia canadensis str. McKiel glutamyl-tRNA synthetase YP_001492486.1 793687 D 293613 CDS YP_001492487.1 157803938 5626065 complement(795318..795440) 1 NC_009879.1 hypothetical protein 795440 5626065 A1E_03875 Rickettsia canadensis str. McKiel hypothetical protein YP_001492487.1 795318 R 293613 CDS YP_001492488.1 157803939 5626066 complement(795489..795788) 1 NC_009879.1 hypothetical protein 795788 5626066 A1E_03880 Rickettsia canadensis str. McKiel hypothetical protein YP_001492488.1 795489 R 293613 CDS YP_001492489.1 157803940 5626067 complement(796213..796347) 1 NC_009879.1 hypothetical protein 796347 5626067 A1E_03885 Rickettsia canadensis str. McKiel hypothetical protein YP_001492489.1 796213 R 293613 CDS YP_001492490.1 157803941 5626068 complement(796669..796899) 1 NC_009879.1 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; hypothetical protein 796899 5626068 A1E_03890 Rickettsia canadensis str. McKiel hypothetical protein YP_001492490.1 796669 R 293613 CDS YP_001492491.1 157803942 5626401 complement(797625..797960) 1 NC_009879.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 797960 cyaY 5626401 cyaY Rickettsia canadensis str. McKiel frataxin-like protein YP_001492491.1 797625 R 293613 CDS YP_001492492.1 157803943 5626402 complement(797957..798964) 1 NC_009879.1 hypothetical protein 798964 5626402 A1E_03900 Rickettsia canadensis str. McKiel hypothetical protein YP_001492492.1 797957 R 293613 CDS YP_001492493.1 157803944 5626403 799276..799575 1 NC_009879.1 COG1559 Predicted periplasmic solute-binding protein; hypothetical protein 799575 5626403 A1E_03905 Rickettsia canadensis str. McKiel hypothetical protein YP_001492493.1 799276 D 293613 CDS YP_001492494.1 157803945 5626404 complement(799559..800716) 1 NC_009879.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 800716 lpxB 5626404 lpxB Rickettsia canadensis str. McKiel lipid-A-disaccharide synthase YP_001492494.1 799559 R 293613 CDS YP_001492495.1 157803946 5626405 complement(800747..800881) 1 NC_009879.1 inorganic polyphosphate/ATP-NAD kinase 800881 ppnK 5626405 ppnK Rickettsia canadensis str. McKiel inorganic polyphosphate/ATP-NAD kinase YP_001492495.1 800747 R 293613 CDS YP_001492496.1 157803947 5626406 complement(801104..801256) 1 NC_009879.1 hypothetical protein 801256 5626406 A1E_03920 Rickettsia canadensis str. McKiel hypothetical protein YP_001492496.1 801104 R 293613 CDS YP_001492497.1 157803948 5626233 complement(801321..801467) 1 NC_009879.1 hypothetical protein 801467 5626233 A1E_03925 Rickettsia canadensis str. McKiel hypothetical protein YP_001492497.1 801321 R 293613 CDS YP_001492498.1 157803949 5626234 complement(801861..802160) 1 NC_009879.1 hypothetical protein 802160 5626234 A1E_03930 Rickettsia canadensis str. McKiel hypothetical protein YP_001492498.1 801861 R 293613 CDS YP_001492499.1 157803950 5626235 complement(802289..802396) 1 NC_009879.1 hypothetical protein 802396 5626235 A1E_03935 Rickettsia canadensis str. McKiel hypothetical protein YP_001492499.1 802289 R 293613 CDS YP_001492500.1 157803951 5626236 complement(802834..804186) 1 NC_009879.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 804186 hslU 5626236 hslU Rickettsia canadensis str. McKiel ATP-dependent protease ATP-binding subunit HslU YP_001492500.1 802834 R 293613 CDS YP_001492501.1 157803952 5626237 complement(804183..804731) 1 NC_009879.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 804731 5626237 A1E_03945 Rickettsia canadensis str. McKiel ATP-dependent protease peptidase subunit YP_001492501.1 804183 R 293613 CDS YP_001492502.1 157803953 5626238 804897..805250 1 NC_009879.1 hypothetical protein 805250 5626238 A1E_03950 Rickettsia canadensis str. McKiel hypothetical protein YP_001492502.1 804897 D 293613 CDS YP_001492503.1 157803954 5626470 805449..805811 1 NC_009879.1 hypothetical protein 805811 5626470 A1E_03955 Rickettsia canadensis str. McKiel hypothetical protein YP_001492503.1 805449 D 293613 CDS YP_001492504.1 157803955 5626471 805804..806820 1 NC_009879.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 806820 5626471 A1E_03960 Rickettsia canadensis str. McKiel aspartate-semialdehyde dehydrogenase YP_001492504.1 805804 D 293613 CDS YP_001492505.1 157803956 5626472 806834..808594 1 NC_009879.1 hypothetical protein 808594 5626472 A1E_03965 Rickettsia canadensis str. McKiel hypothetical protein YP_001492505.1 806834 D 293613 CDS YP_001492506.1 157803957 5626473 808721..810256 1 NC_009879.1 hypothetical protein 810256 5626473 A1E_03970 Rickettsia canadensis str. McKiel hypothetical protein YP_001492506.1 808721 D 293613 CDS YP_001492507.1 157803958 5626474 810394..811710 1 NC_009879.1 hypothetical protein 811710 5626474 A1E_03975 Rickettsia canadensis str. McKiel hypothetical protein YP_001492507.1 810394 D 293613 CDS YP_001492508.1 157803959 5626475 complement(811661..812368) 1 NC_009879.1 hypothetical protein 812368 5626475 A1E_03980 Rickettsia canadensis str. McKiel hypothetical protein YP_001492508.1 811661 R 293613 CDS YP_001492509.1 157803960 5626185 complement(813309..814259) 1 NC_009879.1 hypothetical protein 814259 5626185 A1E_03985 Rickettsia canadensis str. McKiel hypothetical protein YP_001492509.1 813309 R 293613 CDS YP_001492510.1 157803961 5626186 complement(814249..814680) 1 NC_009879.1 hypothetical protein 814680 5626186 A1E_03990 Rickettsia canadensis str. McKiel hypothetical protein YP_001492510.1 814249 R 293613 CDS YP_001492511.1 157803962 5626187 complement(814680..815408) 1 NC_009879.1 hypothetical protein 815408 5626187 A1E_03995 Rickettsia canadensis str. McKiel hypothetical protein YP_001492511.1 814680 R 293613 CDS YP_001492512.1 157803963 5626188 816919..817065 1 NC_009879.1 hypothetical protein 817065 5626188 A1E_04000 Rickettsia canadensis str. McKiel hypothetical protein YP_001492512.1 816919 D 293613 CDS YP_001492513.1 157803964 5626189 817414..817629 1 NC_009879.1 hypothetical protein 817629 5626189 A1E_04005 Rickettsia canadensis str. McKiel hypothetical protein YP_001492513.1 817414 D 293613 CDS YP_001492514.1 157803965 5626190 complement(817943..819190) 1 NC_009879.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 819190 hisS 5626190 hisS Rickettsia canadensis str. McKiel histidyl-tRNA synthetase YP_001492514.1 817943 R 293613 CDS YP_001492515.1 157803966 5625933 complement(819353..820753) 1 NC_009879.1 hypothetical protein 820753 5625933 A1E_04015 Rickettsia canadensis str. McKiel hypothetical protein YP_001492515.1 819353 R 293613 CDS YP_001492516.1 157803967 5625934 complement(820897..822003) 1 NC_009879.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 822003 mnmA 5625934 mnmA Rickettsia canadensis str. McKiel tRNA-specific 2-thiouridylase MnmA YP_001492516.1 820897 R 293613 CDS YP_001492517.1 157803968 5625935 822218..823201 1 NC_009879.1 hypothetical protein 823201 5625935 A1E_04025 Rickettsia canadensis str. McKiel hypothetical protein YP_001492517.1 822218 D 293613 CDS YP_001492518.1 157803969 5625936 complement(823607..823792) 1 NC_009879.1 hypothetical protein 823792 5625936 A1E_04030 Rickettsia canadensis str. McKiel hypothetical protein YP_001492518.1 823607 R 293613 CDS YP_001492519.1 157803970 5625937 complement(824329..824454) 1 NC_009879.1 hypothetical protein 824454 5625937 A1E_04035 Rickettsia canadensis str. McKiel hypothetical protein YP_001492519.1 824329 R 293613 CDS YP_001492520.1 157803971 5625938 complement(824496..824714) 1 NC_009879.1 hypothetical protein 824714 5625938 A1E_04040 Rickettsia canadensis str. McKiel hypothetical protein YP_001492520.1 824496 R 293613 CDS YP_001492521.1 157803972 5626157 complement(825596..826144) 1 NC_009879.1 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 826144 5626157 A1E_04045 Rickettsia canadensis str. McKiel cytochrome C oxidase assembly protein YP_001492521.1 825596 R 293613 CDS YP_001492522.1 157803973 5626158 826234..827124 1 NC_009879.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 827124 5626158 A1E_04050 Rickettsia canadensis str. McKiel RNA polymerase factor sigma-32 YP_001492522.1 826234 D 293613 CDS YP_001492523.1 157803974 5626159 complement(827250..828584) 1 NC_009879.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 828584 tolB 5626159 tolB Rickettsia canadensis str. McKiel translocation protein TolB YP_001492523.1 827250 R 293613 CDS YP_001492524.1 157803975 5626160 complement(828769..829659) 1 NC_009879.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 829659 thyX 5626160 thyX Rickettsia canadensis str. McKiel FAD-dependent thymidylate synthase YP_001492524.1 828769 R 293613 CDS YP_001492525.1 157803976 5626161 complement(830244..830372) 1 NC_009879.1 hypothetical protein 830372 5626161 A1E_04065 Rickettsia canadensis str. McKiel hypothetical protein YP_001492525.1 830244 R 293613 CDS YP_001492526.1 157803977 5626162 complement(830528..831187) 1 NC_009879.1 hypothetical protein 831187 5626162 A1E_04070 Rickettsia canadensis str. McKiel hypothetical protein YP_001492526.1 830528 R 293613 CDS YP_001492527.1 157803978 5625971 831426..831554 1 NC_009879.1 hypothetical protein 831554 5625971 A1E_04075 Rickettsia canadensis str. McKiel hypothetical protein YP_001492527.1 831426 D 293613 CDS YP_001492528.1 157803979 5625972 complement(832040..832246) 1 NC_009879.1 hypothetical protein 832246 5625972 A1E_04080 Rickettsia canadensis str. McKiel hypothetical protein YP_001492528.1 832040 R 293613 CDS YP_001492529.1 157803980 5625973 832412..835087 1 NC_009879.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 835087 5625973 A1E_04085 Rickettsia canadensis str. McKiel DNA mismatch repair protein MutS YP_001492529.1 832412 D 293613 CDS YP_001492530.1 157803981 5625974 complement(835227..836006) 1 NC_009879.1 hypothetical protein 836006 5625974 A1E_04090 Rickettsia canadensis str. McKiel hypothetical protein YP_001492530.1 835227 R 293613 CDS YP_001492531.1 157803982 5625975 complement(836008..836808) 1 NC_009879.1 hypothetical protein 836808 5625975 A1E_04095 Rickettsia canadensis str. McKiel hypothetical protein YP_001492531.1 836008 R 293613 CDS YP_001492532.1 157803983 5625976 complement(836945..837859) 1 NC_009879.1 hypothetical protein 837859 5625976 A1E_04100 Rickettsia canadensis str. McKiel hypothetical protein YP_001492532.1 836945 R 293613 CDS YP_001492533.1 157803984 5625820 838206..838424 1 NC_009879.1 hypothetical protein 838424 5625820 A1E_04105 Rickettsia canadensis str. McKiel hypothetical protein YP_001492533.1 838206 D 293613 CDS YP_001492534.1 157803985 5625821 complement(840013..840180) 1 NC_009879.1 hypothetical protein 840180 5625821 A1E_04110 Rickettsia canadensis str. McKiel hypothetical protein YP_001492534.1 840013 R 293613 CDS YP_001492535.1 157803986 5625822 complement(841156..841311) 1 NC_009879.1 hypothetical protein 841311 5625822 A1E_04120 Rickettsia canadensis str. McKiel hypothetical protein YP_001492535.1 841156 R 293613 CDS YP_001492536.1 157803987 5625823 complement(841693..841881) 1 NC_009879.1 hypothetical protein 841881 5625823 A1E_04125 Rickettsia canadensis str. McKiel hypothetical protein YP_001492536.1 841693 R 293613 CDS YP_001492537.1 157803988 5625824 complement(842599..842769) 1 NC_009879.1 hypothetical protein 842769 5625824 A1E_04130 Rickettsia canadensis str. McKiel hypothetical protein YP_001492537.1 842599 R 293613 CDS YP_001492538.1 157803989 5625825 complement(842858..842956) 1 NC_009879.1 hypothetical protein 842956 5625825 A1E_04135 Rickettsia canadensis str. McKiel hypothetical protein YP_001492538.1 842858 R 293613 CDS YP_001492539.1 157803990 5626348 complement(843134..843499) 1 NC_009879.1 hypothetical protein 843499 5626348 A1E_04140 Rickettsia canadensis str. McKiel hypothetical protein YP_001492539.1 843134 R 293613 CDS YP_001492540.1 157803991 5626349 complement(844507..844620) 1 NC_009879.1 hypothetical protein 844620 5626349 A1E_04150 Rickettsia canadensis str. McKiel hypothetical protein YP_001492540.1 844507 R 293613 CDS YP_001492541.1 157803992 5626350 complement(845381..846793) 1 NC_009879.1 hypothetical protein 846793 5626350 A1E_04155 Rickettsia canadensis str. McKiel hypothetical protein YP_001492541.1 845381 R 293613 CDS YP_001492542.1 157803993 5626351 complement(846803..848578) 1 NC_009879.1 type IV secretion system component VirD4 848578 5626351 A1E_04160 Rickettsia canadensis str. McKiel type IV secretion system component VirD4 YP_001492542.1 846803 R 293613 CDS YP_001492543.1 157803994 5626352 complement(848751..849755) 1 NC_009879.1 type IV secretion system ATPase VirB11 849755 5626352 A1E_04165 Rickettsia canadensis str. McKiel type IV secretion system ATPase VirB11 YP_001492543.1 848751 R 293613 CDS YP_001492544.1 157803995 5626353 complement(849752..851200) 1 NC_009879.1 hypothetical protein 851200 5626353 A1E_04170 Rickettsia canadensis str. McKiel hypothetical protein YP_001492544.1 849752 R 293613 CDS YP_001492545.1 157803996 5626578 complement(851337..851819) 1 NC_009879.1 hypothetical protein 851819 5626578 A1E_04175 Rickettsia canadensis str. McKiel hypothetical protein YP_001492545.1 851337 R 293613 CDS YP_001492546.1 157803997 5626579 complement(851806..852534) 1 NC_009879.1 hypothetical protein 852534 5626579 A1E_04180 Rickettsia canadensis str. McKiel hypothetical protein YP_001492546.1 851806 R 293613 CDS YP_001492547.1 157803998 5626580 853281..853979 1 NC_009879.1 hypothetical protein 853979 5626580 A1E_04185 Rickettsia canadensis str. McKiel hypothetical protein YP_001492547.1 853281 D 293613 CDS YP_001492548.1 157803999 5626581 853981..854733 1 NC_009879.1 hypothetical protein 854733 5626581 A1E_04190 Rickettsia canadensis str. McKiel hypothetical protein YP_001492548.1 853981 D 293613 CDS YP_001492549.1 157804000 5626582 854736..855071 1 NC_009879.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 855071 5626582 A1E_04195 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit C YP_001492549.1 854736 D 293613 CDS YP_001492550.1 157804001 5626583 855204..856490 1 NC_009879.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 856490 5626583 A1E_04200 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit D YP_001492550.1 855204 D 293613 CDS YP_001492551.1 157804002 5626269 856821..857012 1 NC_009879.1 COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hypothetical protein 857012 5626269 A1E_04205 Rickettsia canadensis str. McKiel hypothetical protein YP_001492551.1 856821 D 293613 CDS YP_001492552.1 157804003 5626270 857205..858668 1 NC_009879.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 858668 5626270 A1E_04210 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit D YP_001492552.1 857205 D 293613 CDS YP_001492553.1 157804004 5626271 858731..858883 1 NC_009879.1 COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; antitoxin of toxin-antitoxin system VapB 858883 5626271 A1E_04215 Rickettsia canadensis str. McKiel antitoxin of toxin-antitoxin system VapB YP_001492553.1 858731 D 293613 CDS YP_001492554.1 157804005 5626272 859012..859389 1 NC_009879.1 COG1487 Predicted nucleic acid-binding protein, contains PIN domain; putative monovalent cation/H+ antiporter subunit D 859389 5626272 A1E_04220 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit D YP_001492554.1 859012 D 293613 CDS YP_001492555.1 157804006 5626273 859398..860918 1 NC_009879.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 860918 5626273 A1E_04225 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit D YP_001492555.1 859398 D 293613 CDS YP_001492556.1 157804007 5626274 860925..862979 1 NC_009879.1 COG1770 Protease II; protease II 862979 5626274 A1E_04230 Rickettsia canadensis str. McKiel protease II YP_001492556.1 860925 D 293613 CDS YP_001492557.1 157804008 5626535 863165..864265 1 NC_009879.1 COG0772 Bacterial cell division membrane protein; putative monovalent cation/H+ antiporter subunit D 864265 5626535 A1E_04235 Rickettsia canadensis str. McKiel putative monovalent cation/H+ antiporter subunit D YP_001492557.1 863165 D 293613 CDS YP_001492558.1 157804009 5626537 complement(865044..865316) 1 NC_009879.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 865316 rpsT 5626537 rpsT Rickettsia canadensis str. McKiel 30S ribosomal protein S20 YP_001492558.1 865044 R 293613 CDS YP_001492559.1 157804010 5626538 complement(865335..865745) 1 NC_009879.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 865745 rplQ 5626538 rplQ Rickettsia canadensis str. McKiel 50S ribosomal protein L17 YP_001492559.1 865335 R 293613 CDS YP_001492560.1 157804011 5626539 complement(865758..866780) 1 NC_009879.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 866780 5626539 A1E_04250 Rickettsia canadensis str. McKiel DNA-directed RNA polymerase subunit alpha YP_001492560.1 865758 R 293613 CDS YP_001492561.1 157804012 5625858 complement(866799..867182) 1 NC_009879.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 867182 5625858 A1E_04255 Rickettsia canadensis str. McKiel 30S ribosomal protein S11 YP_001492561.1 866799 R 293613 CDS YP_001492562.1 157804013 5625859 complement(867206..867643) 1 NC_009879.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 867643 rpsM 5625859 rpsM Rickettsia canadensis str. McKiel 30S ribosomal protein S13 YP_001492562.1 867206 R 293613 CDS YP_001492563.1 157804014 5625860 complement(867640..868278) 1 NC_009879.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 868278 adk 5625860 adk Rickettsia canadensis str. McKiel adenylate kinase YP_001492563.1 867640 R 293613 CDS YP_001492564.1 157804015 5625861 complement(868294..869595) 1 NC_009879.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 869595 secY 5625861 secY Rickettsia canadensis str. McKiel preprotein translocase subunit SecY YP_001492564.1 868294 R 293613 CDS YP_001492565.1 157804016 5625862 complement(869599..870060) 1 NC_009879.1 late assembly protein; 50S ribosomal protein L15 870060 rplO 5625862 rplO Rickettsia canadensis str. McKiel 50S ribosomal protein L15 YP_001492565.1 869599 R 293613 CDS YP_001492566.1 157804017 5625863 complement(870074..870265) 1 NC_009879.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 870265 rpmD 5625863 rpmD Rickettsia canadensis str. McKiel 50S ribosomal protein L30 YP_001492566.1 870074 R 293613 CDS YP_001492567.1 157804018 5626776 complement(870300..870818) 1 NC_009879.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 870818 rpsE 5626776 rpsE Rickettsia canadensis str. McKiel 30S ribosomal protein S5 YP_001492567.1 870300 R 293613 CDS YP_001492568.1 157804019 5626777 complement(870836..871192) 1 NC_009879.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 871192 rplR 5626777 rplR Rickettsia canadensis str. McKiel 50S ribosomal protein L18 YP_001492568.1 870836 R 293613 CDS YP_001492569.1 157804020 5626778 complement(871208..871741) 1 NC_009879.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 871741 rplF 5626778 rplF Rickettsia canadensis str. McKiel 50S ribosomal protein L6 YP_001492569.1 871208 R 293613 CDS YP_001492570.1 157804021 5626779 complement(871750..872148) 1 NC_009879.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 872148 rpsH 5626779 rpsH Rickettsia canadensis str. McKiel 30S ribosomal protein S8 YP_001492570.1 871750 R 293613 CDS YP_001492571.1 157804022 5626780 complement(872168..872473) 1 NC_009879.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 872473 rpsN 5626780 rpsN Rickettsia canadensis str. McKiel 30S ribosomal protein S14 YP_001492571.1 872168 R 293613 CDS YP_001492572.1 157804023 5626781 complement(872484..873029) 1 NC_009879.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 873029 rplE 5626781 rplE Rickettsia canadensis str. McKiel 50S ribosomal protein L5 YP_001492572.1 872484 R 293613 CDS YP_001492573.1 157804024 5626023 complement(873029..873358) 1 NC_009879.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 873358 rplX 5626023 rplX Rickettsia canadensis str. McKiel 50S ribosomal protein L24 YP_001492573.1 873029 R 293613 CDS YP_001492574.1 157804025 5626024 complement(873359..873727) 1 NC_009879.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 873727 rplN 5626024 rplN Rickettsia canadensis str. McKiel 50S ribosomal protein L14 YP_001492574.1 873359 R 293613 CDS YP_001492575.1 157804026 5626025 complement(873800..874033) 1 NC_009879.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 874033 rpsQ 5626025 rpsQ Rickettsia canadensis str. McKiel 30S ribosomal protein S17 YP_001492575.1 873800 R 293613 CDS YP_001492576.1 157804027 5626026 complement(874035..874250) 1 NC_009879.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 874250 rpmC 5626026 rpmC Rickettsia canadensis str. McKiel 50S ribosomal protein L29 YP_001492576.1 874035 R 293613 CDS YP_001492577.1 157804028 5626027 complement(874243..874653) 1 NC_009879.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 874653 rplP 5626027 rplP Rickettsia canadensis str. McKiel 50S ribosomal protein L16 YP_001492577.1 874243 R 293613 CDS YP_001492578.1 157804029 5626028 complement(874668..875321) 1 NC_009879.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 875321 rpsC 5626028 rpsC Rickettsia canadensis str. McKiel 30S ribosomal protein S3 YP_001492578.1 874668 R 293613 CDS YP_001492579.1 157804030 5626222 complement(875323..875682) 1 NC_009879.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 875682 rplV 5626222 rplV Rickettsia canadensis str. McKiel 50S ribosomal protein L22 YP_001492579.1 875323 R 293613 CDS YP_001492580.1 157804031 5626223 complement(875691..875969) 1 NC_009879.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 875969 rpsS 5626223 rpsS Rickettsia canadensis str. McKiel 30S ribosomal protein S19 YP_001492580.1 875691 R 293613 CDS YP_001492581.1 157804032 5626224 complement(875994..876815) 1 NC_009879.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 876815 rplB 5626224 rplB Rickettsia canadensis str. McKiel 50S ribosomal protein L2 YP_001492581.1 875994 R 293613 CDS YP_001492582.1 157804033 5626225 complement(876816..877112) 1 NC_009879.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 877112 rplW 5626225 rplW Rickettsia canadensis str. McKiel 50S ribosomal protein L23 YP_001492582.1 876816 R 293613 CDS YP_001492583.1 157804034 5626226 complement(877109..877732) 1 NC_009879.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 877732 rplD 5626226 rplD Rickettsia canadensis str. McKiel 50S ribosomal protein L4 YP_001492583.1 877109 R 293613 CDS YP_001492584.1 157804035 5626227 complement(877842..878489) 1 NC_009879.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 878489 rplC 5626227 rplC Rickettsia canadensis str. McKiel 50S ribosomal protein L3 YP_001492584.1 877842 R 293613 CDS YP_001492585.1 157804036 5626407 complement(878490..878807) 1 NC_009879.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 878807 rpsJ 5626407 rpsJ Rickettsia canadensis str. McKiel 30S ribosomal protein S10 YP_001492585.1 878490 R 293613 CDS YP_001492586.1 157804037 5626408 complement(878901..880085) 1 NC_009879.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 880085 5626408 A1E_04380 Rickettsia canadensis str. McKiel elongation factor Tu YP_001492586.1 878901 R 293613 CDS YP_001492587.1 157804038 5626411 880699..881418 1 NC_009879.1 elongation factor Tu 881418 5626411 A1E_04385 Rickettsia canadensis str. McKiel elongation factor Tu YP_001492587.1 880699 D 293613 CDS YP_001492588.1 157804039 5626911 881677..881778 1 NC_009879.1 COG0566 rRNA methylases; hypothetical protein 881778 5626911 A1E_04390 Rickettsia canadensis str. McKiel hypothetical protein YP_001492588.1 881677 D 293613 CDS YP_001492589.1 157804040 5626912 882124..883515 1 NC_009879.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 883515 fumC 5626912 fumC Rickettsia canadensis str. McKiel fumarate hydratase YP_001492589.1 882124 D 293613 CDS YP_001492590.1 157804041 5626913 883817..883996 1 NC_009879.1 COG0114 Fumarase; hypothetical protein 883996 5626913 A1E_04400 Rickettsia canadensis str. McKiel hypothetical protein YP_001492590.1 883817 D 293613 CDS YP_001492591.1 157804042 5626914 884309..885667 1 NC_009879.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 885667 5626914 A1E_04405 Rickettsia canadensis str. McKiel cell division protein FtsZ YP_001492591.1 884309 D 293613 CDS YP_001492592.1 157804043 5625909 886028..886174 1 NC_009879.1 COG0206 Cell division GTPase; hypothetical protein 886174 5625909 A1E_04410 Rickettsia canadensis str. McKiel hypothetical protein YP_001492592.1 886028 D 293613 CDS YP_001492593.1 157804044 5625910 886353..886610 1 NC_009879.1 COG4574 Serine protease inhibitor ecotin; ecotin precursor 886610 5625910 A1E_04415 Rickettsia canadensis str. McKiel ecotin precursor YP_001492593.1 886353 D 293613 CDS YP_001492594.1 157804045 5625911 complement(886866..887435) 1 NC_009879.1 COG0694 Thioredoxin-like proteins and domains; NifU-like domain-containing protein 887435 5625911 A1E_04420 Rickettsia canadensis str. McKiel NifU-like domain-containing protein YP_001492594.1 886866 R 293613 CDS YP_001492595.1 157804046 5625912 complement(888741..889973) 1 NC_009879.1 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlE 889973 5625912 A1E_04425 Rickettsia canadensis str. McKiel ATP-dependent RNA helicase RhlE YP_001492595.1 888741 R 293613 CDS YP_001492596.1 157804047 5625913 complement(890505..890717) 1 NC_009879.1 cold shock-like protein 890717 5625913 A1E_04430 Rickettsia canadensis str. McKiel cold shock-like protein YP_001492596.1 890505 R 293613 CDS YP_001492597.1 157804048 5625914 complement(891044..891175) 1 NC_009879.1 hypothetical protein 891175 5625914 A1E_04435 Rickettsia canadensis str. McKiel hypothetical protein YP_001492597.1 891044 R 293613 CDS YP_001492598.1 157804049 5626386 complement(892826..892990) 1 NC_009879.1 cell division protein FtsZ 892990 5626386 A1E_04440 Rickettsia canadensis str. McKiel cell division protein FtsZ YP_001492598.1 892826 R 293613 CDS YP_001492599.1 157804050 5626387 complement(893142..893261) 1 NC_009879.1 hypothetical protein 893261 5626387 A1E_04445 Rickettsia canadensis str. McKiel hypothetical protein YP_001492599.1 893142 R 293613 CDS YP_001492600.1 157804051 5626388 893825..893917 1 NC_009879.1 COG1278 Cold shock proteins; hypothetical protein 893917 5626388 A1E_04450 Rickettsia canadensis str. McKiel hypothetical protein YP_001492600.1 893825 D 293613 CDS YP_001492601.1 157804052 5626389 complement(893969..894781) 1 NC_009879.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 894781 ksgA 5626389 ksgA Rickettsia canadensis str. McKiel dimethyladenosine transferase YP_001492601.1 893969 R 293613 CDS YP_001492602.1 157804053 5626540 complement(894903..895790) 1 NC_009879.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein 895790 5626540 A1E_04460 Rickettsia canadensis str. McKiel hypothetical protein YP_001492602.1 894903 R 293613 CDS YP_001492603.1 157804054 5626541 complement(896064..898184) 1 NC_009879.1 COG1452 Organic solvent tolerance protein OstA; dimethyladenosine transferase 898184 ksgA 5626541 ksgA Rickettsia canadensis str. McKiel dimethyladenosine transferase YP_001492603.1 896064 R 293613 CDS YP_001492604.1 157804055 5626542 898509..899843 1 NC_009879.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 899843 xseA 5626542 xseA Rickettsia canadensis str. McKiel exodeoxyribonuclease VII large subunit YP_001492604.1 898509 D 293613 CDS YP_001492605.1 157804056 5626543 899951..900109 1 NC_009879.1 COG1570 Exonuclease VII, large subunit; hypothetical protein 900109 5626543 A1E_04475 Rickettsia canadensis str. McKiel hypothetical protein YP_001492605.1 899951 D 293613 CDS YP_001492606.1 157804057 5626544 901389..902171 1 NC_009879.1 COG0708 Exonuclease III; exodeoxyribonuclease VII large subunit 902171 xseA 5626544 xseA Rickettsia canadensis str. McKiel exodeoxyribonuclease VII large subunit YP_001492606.1 901389 D 293613 CDS YP_001492607.1 157804058 5626040 902439..903782 1 NC_009879.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 903782 engA 5626040 engA Rickettsia canadensis str. McKiel GTP-binding protein EngA YP_001492607.1 902439 D 293613 CDS YP_001492608.1 157804059 5626041 complement(904653..904784) 1 NC_009879.1 hypothetical protein 904784 5626041 A1E_04490 Rickettsia canadensis str. McKiel hypothetical protein YP_001492608.1 904653 R 293613 CDS YP_001492609.1 157804060 5626042 complement(906035..906262) 1 NC_009879.1 hypothetical protein 906262 5626042 A1E_04495 Rickettsia canadensis str. McKiel hypothetical protein YP_001492609.1 906035 R 293613 CDS YP_001492610.1 157804061 5626043 complement(906325..906486) 1 NC_009879.1 COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein 906486 5626043 A1E_04500 Rickettsia canadensis str. McKiel hypothetical protein YP_001492610.1 906325 R 293613 CDS YP_001492611.1 157804062 5626044 complement(907306..908736) 1 NC_009879.1 COG0661 Predicted unusual protein kinase; GTP-binding protein EngA 908736 engA 5626044 engA Rickettsia canadensis str. McKiel GTP-binding protein EngA YP_001492611.1 907306 R 293613 CDS YP_001492612.1 157804063 5626045 complement(908733..909479) 1 NC_009879.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 909479 ubiE 5626045 ubiE Rickettsia canadensis str. McKiel ubiquinone/menaquinone biosynthesis methyltransferase YP_001492612.1 908733 R 293613 CDS YP_001492613.1 157804064 5626754 909507..910328 1 NC_009879.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 910328 5626754 A1E_04515 Rickettsia canadensis str. McKiel formamidopyrimidine-DNA glycosylase YP_001492613.1 909507 D 293613 CDS YP_001492614.1 157804065 5626755 910851..911045 1 NC_009879.1 mannose-1-phosphate guanylyltransferase 911045 5626755 A1E_04520 Rickettsia canadensis str. McKiel mannose-1-phosphate guanylyltransferase YP_001492614.1 910851 D 293613 CDS YP_001492615.1 157804066 5626756 912078..912311 1 NC_009879.1 COG0266 Formamidopyrimidine-DNA glycosylase; hypothetical protein 912311 5626756 A1E_04525 Rickettsia canadensis str. McKiel hypothetical protein YP_001492615.1 912078 D 293613 CDS YP_001492616.1 157804067 5626757 complement(913044..913259) 1 NC_009879.1 COG4553 Poly-beta-hydroxyalkanoate depolymerase; Poly-beta-hydroxyalkanoate depolymerase 913259 5626757 A1E_04530 Rickettsia canadensis str. McKiel Poly-beta-hydroxyalkanoate depolymerase YP_001492616.1 913044 R 293613 CDS YP_001492617.1 157804068 5626758 complement(913776..914585) 1 NC_009879.1 COG0084 Mg-dependent DNase; ubiquinone/menaquinone biosynthesis methyltransferase 914585 ubiE 5626758 ubiE Rickettsia canadensis str. McKiel ubiquinone/menaquinone biosynthesis methyltransferase YP_001492617.1 913776 R 293613 CDS YP_001492618.1 157804069 5626759 complement(914713..916245) 1 NC_009879.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 916245 5626759 A1E_04540 Rickettsia canadensis str. McKiel methionyl-tRNA synthetase YP_001492618.1 914713 R 293613 CDS YP_001492619.1 157804070 5625847 complement(916242..916853) 1 NC_009879.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 916853 tmk 5625847 tmk Rickettsia canadensis str. McKiel thymidylate kinase YP_001492619.1 916242 R 293613 CDS YP_001492620.1 157804071 5625848 917161..918498 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; thymidylate kinase 918498 tdk 5625848 tdk Rickettsia canadensis str. McKiel thymidylate kinase YP_001492620.1 917161 D 293613 CDS YP_001492621.1 157804072 5625849 complement(918495..919337) 1 NC_009879.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 919337 ubiA 5625849 ubiA Rickettsia canadensis str. McKiel 4-hydroxybenzoate polyprenyltransferase YP_001492621.1 918495 R 293613 CDS YP_001492622.1 157804073 5625850 919418..919582 1 NC_009879.1 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; prenyltransferase 919582 ubiA 5625850 ubiA Rickettsia canadensis str. McKiel prenyltransferase YP_001492622.1 919418 D 293613 CDS YP_001492623.1 157804074 5625851 920473..922914 1 NC_009879.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 922914 valS 5625851 valS Rickettsia canadensis str. McKiel valyl-tRNA synthetase YP_001492623.1 920473 D 293613 CDS YP_001492624.1 157804075 5625852 923153..923239 1 NC_009879.1 COG0525 Valyl-tRNA synthetase; hypothetical protein 923239 5625852 A1E_04570 Rickettsia canadensis str. McKiel hypothetical protein YP_001492624.1 923153 D 293613 CDS YP_001492625.1 157804076 5625939 complement(923959..925164) 1 NC_009879.1 COG1373 Predicted ATPase (AAA+ superfamily); ATPase 925164 5625939 A1E_04575 Rickettsia canadensis str. McKiel ATPase YP_001492625.1 923959 R 293613 CDS YP_001492626.1 157804077 5625940 925260..926546 1 NC_009879.1 hypothetical protein 926546 5625940 A1E_04580 Rickettsia canadensis str. McKiel hypothetical protein YP_001492626.1 925260 D 293613 CDS YP_001492627.1 157804078 5625941 926683..926841 1 NC_009879.1 Alpha-(1,3)-fucosyltransferase 926841 5625941 A1E_04585 Rickettsia canadensis str. McKiel Alpha-(1,3)-fucosyltransferase YP_001492627.1 926683 D 293613 CDS YP_001492628.1 157804079 5625942 927798..927899 1 NC_009879.1 hypothetical protein 927899 5625942 A1E_04590 Rickettsia canadensis str. McKiel hypothetical protein YP_001492628.1 927798 D 293613 CDS YP_001492629.1 157804080 5625943 complement(927950..928159) 1 NC_009879.1 COG1322 Uncharacterized protein conserved in bacteria; valyl-tRNA synthetase 928159 valS 5625943 valS Rickettsia canadensis str. McKiel valyl-tRNA synthetase YP_001492629.1 927950 R 293613 CDS YP_001492630.1 157804081 5625944 complement(928260..929537) 1 NC_009879.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 929537 clpX 5625944 clpX Rickettsia canadensis str. McKiel ATP-dependent protease ATP-binding subunit ClpX YP_001492630.1 928260 R 293613 CDS YP_001492631.1 157804082 5626008 complement(929667..930218) 1 NC_009879.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-alanine acetyltransferase 930218 5626008 A1E_04605 Rickettsia canadensis str. McKiel ribosomal-protein-alanine acetyltransferase YP_001492631.1 929667 R 293613 CDS YP_001492632.1 157804083 5626009 complement(930215..930898) 1 NC_009879.1 COG0603 Predicted PP-loop superfamily ATPase; trans-regulatory protein ExsB 930898 5626009 A1E_04610 Rickettsia canadensis str. McKiel trans-regulatory protein ExsB YP_001492632.1 930215 R 293613 CDS YP_001492633.1 157804084 5626011 931419..933161 1 NC_009879.1 multidrug resistance protein 933161 5626011 A1E_04615 Rickettsia canadensis str. McKiel multidrug resistance protein YP_001492633.1 931419 D 293613 CDS YP_001492634.1 157804085 5626012 933404..933646 1 NC_009879.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; hypothetical protein 933646 5626012 A1E_04620 Rickettsia canadensis str. McKiel hypothetical protein YP_001492634.1 933404 D 293613 CDS YP_001492635.1 157804086 5626855 934085..934207 1 NC_009879.1 bicyclomycin resistance protein 934207 5626855 A1E_04625 Rickettsia canadensis str. McKiel bicyclomycin resistance protein YP_001492635.1 934085 D 293613 CDS YP_001492636.1 157804087 5626856 complement(934662..934850) 1 NC_009879.1 hypothetical protein 934850 5626856 A1E_04630 Rickettsia canadensis str. McKiel hypothetical protein YP_001492636.1 934662 R 293613 CDS YP_001492637.1 157804088 5626857 934898..934999 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 934999 5626857 A1E_04635 Rickettsia canadensis str. McKiel hypothetical protein YP_001492637.1 934898 D 293613 CDS YP_001492638.1 157804089 5626858 934992..936239 1 NC_009879.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; hypothetical protein 936239 5626858 A1E_04640 Rickettsia canadensis str. McKiel hypothetical protein YP_001492638.1 934992 D 293613 CDS YP_001492639.1 157804090 5626859 936232..936897 1 NC_009879.1 lipoprotein releasing system ATP-binding protein LolD 936897 5626859 A1E_04645 Rickettsia canadensis str. McKiel lipoprotein releasing system ATP-binding protein LolD YP_001492639.1 936232 D 293613 CDS YP_001492640.1 157804091 5626860 936953..938836 1 NC_009879.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; hypothetical protein 938836 5626860 A1E_04650 Rickettsia canadensis str. McKiel hypothetical protein YP_001492640.1 936953 D 293613 CDS YP_001492641.1 157804092 5626524 938943..940184 1 NC_009879.1 COG4536 Putative Mg2+ and Co2+ transporter CorB; hypothetical protein 940184 5626524 A1E_04655 Rickettsia canadensis str. McKiel hypothetical protein YP_001492641.1 938943 D 293613 CDS YP_001492642.1 157804093 5626525 940177..942177 1 NC_009879.1 cytochrome c-type biogenesis protein ccmF 942177 5626525 A1E_04660 Rickettsia canadensis str. McKiel cytochrome c-type biogenesis protein ccmF YP_001492642.1 940177 D 293613 CDS YP_001492643.1 157804094 5626526 complement(942597..942725) 1 NC_009879.1 hypothetical protein 942725 5626526 A1E_04665 Rickettsia canadensis str. McKiel hypothetical protein YP_001492643.1 942597 R 293613 CDS YP_001492644.1 157804095 5626527 complement(943101..943208) 1 NC_009879.1 COG1138 Cytochrome c biogenesis factor; hypothetical protein 943208 5626527 A1E_04670 Rickettsia canadensis str. McKiel hypothetical protein YP_001492644.1 943101 R 293613 CDS YP_001492645.1 157804096 5626528 complement(943592..948505) 1 NC_009879.1 COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain; Outer membrane protein B 948505 5626528 A1E_04675 Rickettsia canadensis str. McKiel Outer membrane protein B YP_001492645.1 943592 R 293613 CDS YP_001492646.1 157804097 5626529 complement(948876..949481) 1 NC_009879.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein 949481 5626529 A1E_04680 Rickettsia canadensis str. McKiel guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein YP_001492646.1 948876 R 293613 CDS YP_001492647.1 157804098 5626882 complement(949883..950827) 1 NC_009879.1 COG1472 Beta-glucosidase-related glycosidases; ATP-dependent protease ATP-binding subunit 950827 clpX 5626882 clpX Rickettsia canadensis str. McKiel ATP-dependent protease ATP-binding subunit YP_001492647.1 949883 R 293613 CDS YP_001492648.1 157804099 5626883 complement(951048..951929) 1 NC_009879.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 951929 5626883 A1E_04690 Rickettsia canadensis str. McKiel lipid A biosynthesis lauroyl acyltransferase YP_001492648.1 951048 R 293613 CDS YP_001492649.1 157804100 5626884 complement(951892..952872) 1 NC_009879.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 952872 lpxK 5626884 lpxK Rickettsia canadensis str. McKiel tetraacyldisaccharide 4'-kinase YP_001492649.1 951892 R 293613 CDS YP_001492650.1 157804101 5626885 complement(953054..953908) 1 NC_009879.1 COG0739 Membrane proteins related to metalloendopeptidases; periplasmic protein 953908 5626885 A1E_04700 Rickettsia canadensis str. McKiel periplasmic protein YP_001492650.1 953054 R 293613 CDS YP_001492651.1 157804102 5626886 complement(953872..954189) 1 NC_009879.1 tetraacyldisaccharide 4'-kinase 954189 lpxK 5626886 lpxK Rickettsia canadensis str. McKiel tetraacyldisaccharide 4'-kinase YP_001492651.1 953872 R 293613 CDS YP_001492652.1 157804103 5626887 complement(954527..954667) 1 NC_009879.1 COG2961 Protein involved in catabolism of external DNA; hypothetical protein 954667 5626887 A1E_04710 Rickettsia canadensis str. McKiel hypothetical protein YP_001492652.1 954527 R 293613 CDS YP_001492653.1 157804104 5626117 complement(955287..957356) 1 NC_009879.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 957356 ligA 5626117 ligA Rickettsia canadensis str. McKiel NAD-dependent DNA ligase LigA YP_001492653.1 955287 R 293613 CDS YP_001492654.1 157804105 5626118 complement(957373..959982) 1 NC_009879.1 COG4748 Uncharacterized conserved protein; NAD-dependent DNA ligase LigA 959982 ligA 5626118 ligA Rickettsia canadensis str. McKiel NAD-dependent DNA ligase LigA YP_001492654.1 957373 R 293613 CDS YP_001492655.1 157804106 5626119 complement(960095..961180) 1 NC_009879.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 961180 tgt 5626119 tgt Rickettsia canadensis str. McKiel queuine tRNA-ribosyltransferase YP_001492655.1 960095 R 293613 CDS YP_001492656.1 157804107 5626120 complement(963392..963514) 1 NC_009879.1 COG0183 Acetyl-CoA acetyltransferase; Poly-beta-hydroxybutyrate polymerase 963514 5626120 A1E_04750 Rickettsia canadensis str. McKiel Poly-beta-hydroxybutyrate polymerase YP_001492656.1 963392 R 293613 CDS YP_001492657.1 157804108 5626121 964081..965580 1 NC_009879.1 COG3202 ATP/ADP translocase; ADP,ATP carrier protein 965580 5626121 A1E_04755 Rickettsia canadensis str. McKiel ADP,ATP carrier protein YP_001492657.1 964081 D 293613 CDS YP_001492658.1 157804109 5626122 complement(966034..966930) 1 NC_009879.1 COG1253 Hemolysins and related proteins containing CBS domains; acetyl-CoA acetyltransferase 966930 5626122 A1E_04760 Rickettsia canadensis str. McKiel acetyl-CoA acetyltransferase YP_001492658.1 966034 R 293613 CDS YP_001492659.1 157804110 5626572 complement(966947..967465) 1 NC_009879.1 COG0319 Predicted metal-dependent hydrolase; putative metalloprotease 967465 5626572 A1E_04765 Rickettsia canadensis str. McKiel putative metalloprotease YP_001492659.1 966947 R 293613 CDS YP_001492660.1 157804111 5626573 complement(967655..968545) 1 NC_009879.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 968545 5626573 A1E_04770 Rickettsia canadensis str. McKiel lipoyl synthase YP_001492660.1 967655 R 293613 CDS YP_001492661.1 157804112 5626574 complement(968538..969800) 1 NC_009879.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 969800 glyA 5626574 glyA Rickettsia canadensis str. McKiel serine hydroxymethyltransferase YP_001492661.1 968538 R 293613 CDS YP_001492662.1 157804113 5626575 complement(970011..970658) 1 NC_009879.1 COG0400 Predicted esterase; Serine esterase 970658 5626575 A1E_04780 Rickettsia canadensis str. McKiel Serine esterase YP_001492662.1 970011 R 293613 CDS YP_001492663.1 157804114 5626576 complement(970753..971067) 1 NC_009879.1 COG0278 Glutaredoxin-related protein; glutaredoxin-like protein grla 971067 5626576 A1E_04785 Rickettsia canadensis str. McKiel glutaredoxin-like protein grla YP_001492663.1 970753 R 293613 CDS YP_001492664.1 157804115 5626577 971283..971912 1 NC_009879.1 COG0177 Predicted EndoIII-related endonuclease; endonuclease III 971912 5626577 A1E_04790 Rickettsia canadensis str. McKiel endonuclease III YP_001492664.1 971283 D 293613 CDS YP_001492665.1 157804116 5625986 complement(972127..972966) 1 NC_009879.1 COG0313 Predicted methyltransferases; hypothetical protein 972966 5625986 A1E_04795 Rickettsia canadensis str. McKiel hypothetical protein YP_001492665.1 972127 R 293613 CDS YP_001492666.1 157804117 5625987 972992..974110 1 NC_009879.1 ABC-type transport systems periplasmic component 974110 5625987 A1E_04800 Rickettsia canadensis str. McKiel ABC-type transport systems periplasmic component YP_001492666.1 972992 D 293613 CDS YP_001492667.1 157804118 5625988 complement(974312..974476) 1 NC_009879.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 974476 tatA 5625988 tatA Rickettsia canadensis str. McKiel twin arginine translocase protein A YP_001492667.1 974312 R 293613 CDS YP_001492668.1 157804119 5625989 974553..975149 1 NC_009879.1 COG1267 Phosphatidylglycerophosphatase A and related proteins; serine hydroxymethyltransferase 975149 glyA 5625989 glyA Rickettsia canadensis str. McKiel serine hydroxymethyltransferase YP_001492668.1 974553 D 293613 CDS YP_001492669.1 157804120 5625990 975220..975537 1 NC_009879.1 COG0261 Ribosomal protein L21; 50S ribosomal protein L21 975537 rplU 5625990 rplU Rickettsia canadensis str. McKiel 50S ribosomal protein L21 YP_001492669.1 975220 D 293613 CDS YP_001492670.1 157804121 5625991 975562..975822 1 NC_009879.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 975822 rpmA 5625991 rpmA Rickettsia canadensis str. McKiel 50S ribosomal protein L27 YP_001492670.1 975562 D 293613 CDS YP_001492671.1 157804122 5625787 976119..977324 1 NC_009879.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 977324 5625787 A1E_04825 Rickettsia canadensis str. McKiel aspartate kinase YP_001492671.1 976119 D 293613 CDS YP_001492672.1 157804123 5625788 977627..978127 1 NC_009879.1 COG0527 Aspartokinases; hypothetical protein 978127 5625788 A1E_04830 Rickettsia canadensis str. McKiel hypothetical protein YP_001492672.1 977627 D 293613 CDS YP_001492673.1 157804124 5625789 complement(978418..979665) 1 NC_009879.1 proline/betaine transporter 979665 5625789 A1E_04835 Rickettsia canadensis str. McKiel proline/betaine transporter YP_001492673.1 978418 R 293613 CDS YP_001492674.1 157804125 5625790 complement(980444..980581) 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 980581 5625790 A1E_04840 Rickettsia canadensis str. McKiel hypothetical protein YP_001492674.1 980444 R 293613 CDS YP_001492675.1 157804126 5625791 complement(980588..980944) 1 NC_009879.1 COG1426 Uncharacterized protein conserved in bacteria; hypothetical protein 980944 5625791 A1E_04845 Rickettsia canadensis str. McKiel hypothetical protein YP_001492675.1 980588 R 293613 CDS YP_001492676.1 157804127 5625792 complement(980948..985702) 1 NC_009879.1 COG2902 NAD-specific glutamate dehydrogenase; aspartate kinase 985702 5625792 A1E_04850 Rickettsia canadensis str. McKiel aspartate kinase YP_001492676.1 980948 R 293613 CDS YP_001492677.1 157804128 5626788 985785..987122 1 NC_009879.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 987122 trmE 5626788 trmE Rickettsia canadensis str. McKiel tRNA modification GTPase TrmE YP_001492677.1 985785 D 293613 CDS YP_001492678.1 157804129 5626789 987344..988708 1 NC_009879.1 COG0486 Predicted GTPase; tRNA modification GTPase TrmE 988708 trmE 5626789 trmE Rickettsia canadensis str. McKiel tRNA modification GTPase TrmE YP_001492678.1 987344 D 293613 CDS YP_001492679.1 157804130 5626790 990368..991399 1 NC_009879.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 991399 recA 5626790 recA Rickettsia canadensis str. McKiel recombinase A YP_001492679.1 990368 D 293613 CDS YP_001492680.1 157804131 5626791 991392..992117 1 NC_009879.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 992117 fabG 5626791 fabG Rickettsia canadensis str. McKiel 3-ketoacyl-(acyl-carrier-protein) reductase YP_001492680.1 991392 D 293613 CDS YP_001492681.1 157804132 5626792 992277..992537 1 NC_009879.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 992537 acpP 5626792 acpP Rickettsia canadensis str. McKiel acyl carrier protein YP_001492681.1 992277 D 293613 CDS YP_001492682.1 157804133 5626793 992574..993854 1 NC_009879.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 993854 5626793 A1E_04880 Rickettsia canadensis str. McKiel 3-oxoacyl-(acyl carrier protein) synthase II YP_001492682.1 992574 D 293613 CDS YP_001492683.1 157804134 5626321 995726..996793 1 NC_009879.1 hypothetical protein 996793 5626321 A1E_04910 Rickettsia canadensis str. McKiel hypothetical protein YP_001492683.1 995726 D 293613 CDS YP_001492684.1 157804135 5626322 996812..997048 1 NC_009879.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; 3-oxoacyl-(acyl carrier protein) synthase II 997048 5626322 A1E_04915 Rickettsia canadensis str. McKiel 3-oxoacyl-(acyl carrier protein) synthase II YP_001492684.1 996812 D 293613 CDS YP_001492685.1 157804136 5626323 complement(997578..998156) 1 NC_009879.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 998156 gmk 5626323 gmk Rickettsia canadensis str. McKiel guanylate kinase YP_001492685.1 997578 R 293613 CDS YP_001492686.1 157804137 5626324 complement(998167..998400) 1 NC_009879.1 COG1396 Predicted transcriptional regulators; hypothetical protein 998400 5626324 A1E_04925 Rickettsia canadensis str. McKiel hypothetical protein YP_001492686.1 998167 R 293613 CDS YP_001492687.1 157804138 5626325 complement(998954..999793) 1 NC_009879.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 999793 5626325 A1E_04930 Rickettsia canadensis str. McKiel rod shape-determining protein MreC YP_001492687.1 998954 R 293613 CDS YP_001492688.1 157804139 5626326 complement(999796..1000836) 1 NC_009879.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1000836 5626326 A1E_04935 Rickettsia canadensis str. McKiel rod shape-determining protein MreB YP_001492688.1 999796 R 293613 CDS YP_001492689.1 157804140 5626670 complement(1001019..1002020) 1 NC_009879.1 COG0795 Predicted permeases; hypothetical protein 1002020 5626670 A1E_04940 Rickettsia canadensis str. McKiel hypothetical protein YP_001492689.1 1001019 R 293613 CDS YP_001492690.1 157804141 5626672 complement(1002581..1003048) 1 NC_009879.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; guanylate kinase 1003048 gmk 5626672 gmk Rickettsia canadensis str. McKiel guanylate kinase YP_001492690.1 1002581 R 293613 CDS YP_001492691.1 157804142 5626673 complement(1003389..1004342) 1 NC_009879.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 1004342 5626673 A1E_04950 Rickettsia canadensis str. McKiel 3-oxoacyl-(acyl carrier protein) synthase III YP_001492691.1 1003389 R 293613 CDS YP_001492692.1 157804143 5626674 complement(1004355..1004555) 1 NC_009879.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1004555 rpmF 5626674 rpmF Rickettsia canadensis str. McKiel 50S ribosomal protein L32 YP_001492692.1 1004355 R 293613 CDS YP_001492693.1 157804144 5626263 1004658..1005131 1 NC_009879.1 COG2913 Small protein A (tmRNA-binding); hypothetical protein 1005131 5626263 A1E_04960 Rickettsia canadensis str. McKiel hypothetical protein YP_001492693.1 1004658 D 293613 CDS YP_001492694.1 157804145 5626264 1005296..1006207 1 NC_009879.1 COG0552 Signal recognition particle GTPase; 50S ribosomal protein L32 1006207 rpmF 5626264 rpmF Rickettsia canadensis str. McKiel 50S ribosomal protein L32 YP_001492694.1 1005296 D 293613 CDS YP_001492695.1 157804146 5626265 1006343..1008970 1 NC_009879.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1008970 5626265 A1E_04970 Rickettsia canadensis str. McKiel DNA polymerase I YP_001492695.1 1006343 D 293613 CDS YP_001492696.1 157804147 5626266 complement(1009212..1012814) 1 NC_009879.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1012814 dnaE 5626266 dnaE Rickettsia canadensis str. McKiel DNA polymerase III subunit alpha YP_001492696.1 1009212 R 293613 CDS YP_001492697.1 157804148 5626267 complement(1013016..1014335) 1 NC_009879.1 UDP-glucose 6-dehydrogenase 1014335 5626267 A1E_04980 Rickettsia canadensis str. McKiel UDP-glucose 6-dehydrogenase YP_001492697.1 1013016 R 293613 CDS YP_001492698.1 157804149 5626268 1014596..1017106 1 NC_009879.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; hypothetical protein 1017106 5626268 A1E_04985 Rickettsia canadensis str. McKiel hypothetical protein YP_001492698.1 1014596 D 293613 CDS YP_001492699.1 157804150 5626805 1017160..1018542 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; ampG protein 1018542 5626805 A1E_04990 Rickettsia canadensis str. McKiel ampG protein YP_001492699.1 1017160 D 293613 CDS YP_001492700.1 157804151 5626806 1018601..1019356 1 NC_009879.1 COG0805 Sec-independent protein secretion pathway component TatC; DNA polymerase III subunit alpha 1019356 dnaE 5626806 dnaE Rickettsia canadensis str. McKiel DNA polymerase III subunit alpha YP_001492700.1 1018601 D 293613 CDS YP_001492701.1 157804152 5626807 1019334..1020611 1 NC_009879.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1020611 5626807 A1E_05000 Rickettsia canadensis str. McKiel seryl-tRNA synthetase YP_001492701.1 1019334 D 293613 CDS YP_001492702.1 157804153 5626808 1020985..1023417 1 NC_009879.1 Type IV secretion/conjugal transfer ATPase, VirB4 family protein 1023417 5626808 A1E_05005 Rickettsia canadensis str. McKiel Type IV secretion/conjugal transfer ATPase, VirB4 family protein YP_001492702.1 1020985 D 293613 CDS YP_001492703.1 157804154 5626809 1023567..1027058 1 NC_009879.1 COG3451 Type IV secretory pathway, VirB4 components; hypothetical protein 1027058 5626809 A1E_05010 Rickettsia canadensis str. McKiel hypothetical protein YP_001492703.1 1023567 D 293613 CDS YP_001492704.1 157804155 5626810 1027063..1027971 1 NC_009879.1 tellurium resistance protein TerC 1027971 5626810 A1E_05015 Rickettsia canadensis str. McKiel tellurium resistance protein TerC YP_001492704.1 1027063 D 293613 CDS YP_001492705.1 157804156 5626111 1028015..1028446 1 NC_009879.1 hypothetical protein 1028446 5626111 A1E_05020 Rickettsia canadensis str. McKiel hypothetical protein YP_001492705.1 1028015 D 293613 CDS YP_001492706.1 157804157 5626112 1028660..1028737 1 NC_009879.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 1028737 5626112 A1E_05025 Rickettsia canadensis str. McKiel hypothetical protein YP_001492706.1 1028660 D 293613 CDS YP_001492707.1 157804158 5626113 1028886..1030550 1 NC_009879.1 COG0500 SAM-dependent methyltransferases; seryl-tRNA synthetase 1030550 5626113 A1E_05030 Rickettsia canadensis str. McKiel seryl-tRNA synthetase YP_001492707.1 1028886 D 293613 CDS YP_001492708.1 157804159 5626114 1030704..1031321 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1031321 5626114 A1E_05035 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit J YP_001492708.1 1030704 D 293613 CDS YP_001492709.1 157804160 5626115 1031314..1031628 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1031628 5626115 A1E_05040 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit K YP_001492709.1 1031314 D 293613 CDS YP_001492710.1 157804161 5626116 1031631..1033616 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1033616 5626116 A1E_05045 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit L YP_001492710.1 1031631 D 293613 CDS YP_001492711.1 157804162 5626606 1033753..1035234 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1035234 5626606 A1E_05050 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit M YP_001492711.1 1033753 D 293613 CDS YP_001492712.1 157804163 5626607 1035446..1036159 1 NC_009879.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1036159 5626607 A1E_05055 Rickettsia canadensis str. McKiel cytochrome c biogenesis protein CcmA YP_001492712.1 1035446 D 293613 CDS YP_001492713.1 157804164 5626608 complement(1036156..1036293) 1 NC_009879.1 COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component; hypothetical protein 1036293 5626608 A1E_05060 Rickettsia canadensis str. McKiel hypothetical protein YP_001492713.1 1036156 R 293613 CDS YP_001492714.1 157804165 5626609 1036597..1036794 1 NC_009879.1 COG1373 Predicted ATPase (AAA+ superfamily); NADH dehydrogenase subunit M 1036794 5626609 A1E_05065 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit M YP_001492714.1 1036597 D 293613 CDS YP_001492715.1 157804166 5626610 complement(1037352..1037831) 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1037831 5626610 A1E_05070 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit I YP_001492715.1 1037352 R 293613 CDS YP_001492716.1 157804167 5626611 complement(1037983..1038147) 1 NC_009879.1 COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); hypothetical protein 1038147 5626611 A1E_05075 Rickettsia canadensis str. McKiel hypothetical protein YP_001492716.1 1037983 R 293613 CDS YP_001492717.1 157804168 5626822 complement(1038369..1039388) 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1039388 5626822 A1E_05080 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit H YP_001492717.1 1038369 R 293613 CDS YP_001492718.1 157804169 5626823 complement(1039630..1041660) 1 NC_009879.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 1041660 5626823 A1E_05085 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit G YP_001492718.1 1039630 R 293613 CDS YP_001492719.1 157804170 5626824 complement(1041833..1042189) 1 NC_009879.1 COG3671 Predicted membrane protein; NADH dehydrogenase subunit G 1042189 5626824 A1E_05090 Rickettsia canadensis str. McKiel NADH dehydrogenase subunit G YP_001492719.1 1041833 R 293613 CDS YP_001492720.1 157804171 5626825 complement(1042559..1045192) 1 NC_009879.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1045192 5626825 A1E_05095 Rickettsia canadensis str. McKiel aconitate hydratase YP_001492720.1 1042559 R 293613 CDS YP_001492721.1 157804172 5626826 complement(1045341..1045655) 1 NC_009879.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1045655 atpC 5626826 atpC Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit epsilon YP_001492721.1 1045341 R 293613 CDS YP_001492722.1 157804173 5626827 complement(1045748..1047169) 1 NC_009879.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1047169 5626827 A1E_05105 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit beta YP_001492722.1 1045748 R 293613 CDS YP_001492723.1 157804174 5626280 complement(1047277..1048143) 1 NC_009879.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1048143 5626280 A1E_05110 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit gamma YP_001492723.1 1047277 R 293613 CDS YP_001492724.1 157804175 5626281 complement(1048251..1049789) 1 NC_009879.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1049789 5626281 A1E_05115 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit alpha YP_001492724.1 1048251 R 293613 CDS YP_001492725.1 157804176 5626282 complement(1049914..1050558) 1 NC_009879.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1050558 5626282 A1E_05120 Rickettsia canadensis str. McKiel F0F1 ATP synthase subunit delta YP_001492725.1 1049914 R 293613 CDS YP_001492726.1 157804177 5626283 complement(1050621..1052009) 1 NC_009879.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1052009 5626283 A1E_05125 Rickettsia canadensis str. McKiel dihydrolipoamide dehydrogenase YP_001492726.1 1050621 R 293613 CDS YP_001492727.1 157804178 5626284 complement(1052682..1052801) 1 NC_009879.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; hypothetical protein 1052801 5626284 A1E_05130 Rickettsia canadensis str. McKiel hypothetical protein YP_001492727.1 1052682 R 293613 CDS YP_001492728.1 157804179 5626285 complement(1053416..1055788) 1 NC_009879.1 COG5009 Membrane carboxypeptidase/penicillin-binding protein; 1A family penicillin-binding protein 1055788 5626285 A1E_05135 Rickettsia canadensis str. McKiel 1A family penicillin-binding protein YP_001492728.1 1053416 R 293613 CDS YP_001492729.1 157804180 5626046 complement(1055957..1057297) 1 NC_009879.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1057297 5626046 A1E_05140 Rickettsia canadensis str. McKiel (dimethylallyl)adenosine tRNA methylthiotransferase YP_001492729.1 1055957 R 293613 CDS YP_001492730.1 157804181 5626047 complement(1057658..1057840) 1 NC_009879.1 hypothetical protein 1057840 5626047 A1E_05145 Rickettsia canadensis str. McKiel hypothetical protein YP_001492730.1 1057658 R 293613 CDS YP_001492731.1 157804182 5626048 complement(1057937..1058014) 1 NC_009879.1 hypothetical protein 1058014 5626048 A1E_05150 Rickettsia canadensis str. McKiel hypothetical protein YP_001492731.1 1057937 R 293613 CDS YP_001492732.1 157804183 5626049 1058486..1058809 1 NC_009879.1 COG0621 2-methylthioadenine synthetase; hypothetical protein 1058809 5626049 A1E_05155 Rickettsia canadensis str. McKiel hypothetical protein YP_001492732.1 1058486 D 293613 CDS YP_001492733.1 157804184 5626050 1058809..1059030 1 NC_009879.1 AAA family ATPase 1059030 5626050 A1E_05160 Rickettsia canadensis str. McKiel AAA family ATPase YP_001492733.1 1058809 D 293613 CDS YP_001492734.1 157804185 5626051 complement(1059845..1059946) 1 NC_009879.1 hypothetical protein 1059946 5626051 A1E_05165 Rickettsia canadensis str. McKiel hypothetical protein YP_001492734.1 1059845 R 293613 CDS YP_001492735.1 157804186 5625966 complement(1059983..1060114) 1 NC_009879.1 COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein 1060114 5625966 A1E_05170 Rickettsia canadensis str. McKiel hypothetical protein YP_001492735.1 1059983 R 293613 CDS YP_001492736.1 157804187 5625967 complement(1060217..1060696) 1 NC_009879.1 hypothetical protein 1060696 5625967 A1E_05175 Rickettsia canadensis str. McKiel hypothetical protein YP_001492736.1 1060217 R 293613 CDS YP_001492737.1 157804188 5625968 complement(1060689..1062416) 1 NC_009879.1 COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein kefb (kefb) 1062416 5625968 A1E_05180 Rickettsia canadensis str. McKiel glutathione-regulated potassium-efflux system protein kefb (kefb) YP_001492737.1 1060689 R 293613 CDS YP_001492738.1 157804189 5625969 complement(1062413..1062739) 1 NC_009879.1 COG0799 Uncharacterized homolog of plant Iojap protein; Iojap-related protein 1062739 5625969 A1E_05185 Rickettsia canadensis str. McKiel Iojap-related protein YP_001492738.1 1062413 R 293613 CDS YP_001492739.1 157804190 5625970 1062898..1063149 1 NC_009879.1 hypothetical protein 1063149 5625970 A1E_05190 Rickettsia canadensis str. McKiel hypothetical protein YP_001492739.1 1062898 D 293613 CDS YP_001492740.1 157804191 5626369 complement(1063487..1063675) 1 NC_009879.1 hypothetical protein 1063675 5626369 A1E_05195 Rickettsia canadensis str. McKiel hypothetical protein YP_001492740.1 1063487 R 293613 CDS YP_001492741.1 157804192 5626370 complement(1063917..1064090) 1 NC_009879.1 hypothetical protein 1064090 5626370 A1E_05200 Rickettsia canadensis str. McKiel hypothetical protein YP_001492741.1 1063917 R 293613 CDS YP_001492742.1 157804193 5626371 complement(1065107..1065220) 1 NC_009879.1 hypothetical protein 1065220 5626371 A1E_05205 Rickettsia canadensis str. McKiel hypothetical protein YP_001492742.1 1065107 R 293613 CDS YP_001492743.1 157804194 5626372 complement(1066056..1066175) 1 NC_009879.1 hypothetical protein 1066175 5626372 A1E_05210 Rickettsia canadensis str. McKiel hypothetical protein YP_001492743.1 1066056 R 293613 CDS YP_001492744.1 157804195 5626373 complement(1066175..1066288) 1 NC_009879.1 hypothetical protein 1066288 5626373 A1E_05215 Rickettsia canadensis str. McKiel hypothetical protein YP_001492744.1 1066175 R 293613 CDS YP_001492745.1 157804196 5626374 complement(1066266..1066466) 1 NC_009879.1 cell surface antigen-like protein Sca13 1066466 5626374 A1E_05220 Rickettsia canadensis str. McKiel cell surface antigen-like protein Sca13 YP_001492745.1 1066266 R 293613 CDS YP_001492746.1 157804197 5625804 complement(1067129..1067230) 1 NC_009879.1 hypothetical protein 1067230 5625804 A1E_05225 Rickettsia canadensis str. McKiel hypothetical protein YP_001492746.1 1067129 R 293613 CDS YP_001492747.1 157804198 5625805 complement(1067331..1067519) 1 NC_009879.1 COG0271 Stress-induced morphogen (activity unknown); dihydrolipoamide dehydrogenase 1067519 5625805 A1E_05230 Rickettsia canadensis str. McKiel dihydrolipoamide dehydrogenase YP_001492747.1 1067331 R 293613 CDS YP_001492748.1 157804199 5625807 1069123..1069338 1 NC_009879.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1069338 infA 5625807 infA Rickettsia canadensis str. McKiel translation initiation factor IF-1 YP_001492748.1 1069123 D 293613 CDS YP_001492749.1 157804200 5625808 1069351..1069959 1 NC_009879.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1069959 5625808 A1E_05240 Rickettsia canadensis str. McKiel Maf-like protein YP_001492749.1 1069351 D 293613 CDS YP_001492750.1 157804201 5625798 complement(1070097..1070528) 1 NC_009879.1 COG1734 DnaK suppressor protein; Maf-like protein 1070528 5625798 A1E_05245 Rickettsia canadensis str. McKiel Maf-like protein YP_001492750.1 1070097 R 293613 CDS YP_001492751.1 157804202 5625799 complement(1070634..1071551) 1 NC_009879.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1071551 xerC 5625799 xerC Rickettsia canadensis str. McKiel site-specific tyrosine recombinase XerC YP_001492751.1 1070634 R 293613 CDS YP_001492752.1 157804203 5625800 complement(1071874..1072476) 1 NC_009879.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phospholipase D (PLD) superfamily protein 1072476 5625800 A1E_05255 Rickettsia canadensis str. McKiel phospholipase D (PLD) superfamily protein YP_001492752.1 1071874 R 293613 CDS YP_001492753.1 157804204 5625801 complement(1074399..1076027) 1 NC_009879.1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; UbiD family decarboxylase 1076027 5625801 A1E_05260 Rickettsia canadensis str. McKiel UbiD family decarboxylase YP_001492753.1 1074399 R 293613 CDS YP_001492754.1 157804205 5625802 complement(1076229..1077803) 1 NC_009879.1 COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase 1077803 5625802 A1E_05265 Rickettsia canadensis str. McKiel parvulin-like peptidyl-prolyl isomerase YP_001492754.1 1076229 R 293613 CDS YP_001492755.1 157804206 5625803 complement(1078023..1084679) 1 NC_009879.1 COG3210 Large exoproteins involved in heme utilization or adhesion; 190-kDa cell surface antigen 1084679 5625803 A1E_05270 Rickettsia canadensis str. McKiel 190-kDa cell surface antigen YP_001492755.1 1078023 R 293613 CDS YP_001492756.1 157804207 5625869 complement(1085152..1087386) 1 NC_009879.1 cell division protein FtsK-like protein 1087386 5625869 A1E_05275 Rickettsia canadensis str. McKiel cell division protein FtsK-like protein YP_001492756.1 1085152 R 293613 CDS YP_001492757.1 157804208 5625870 complement(1087621..1087995) 1 NC_009879.1 hypothetical protein 1087995 5625870 A1E_05280 Rickettsia canadensis str. McKiel hypothetical protein YP_001492757.1 1087621 R 293613 CDS YP_001492758.1 157804209 5625871 complement(1088089..1088355) 1 NC_009879.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; site-specific tyrosine recombinase XerC 1088355 xerC 5625871 xerC Rickettsia canadensis str. McKiel site-specific tyrosine recombinase XerC YP_001492758.1 1088089 R 293613 CDS YP_001492759.1 157804210 5625872 1088503..1089288 1 NC_009879.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1089288 5625872 A1E_05290 Rickettsia canadensis str. McKiel methionine aminopeptidase YP_001492759.1 1088503 D 293613 CDS YP_001492760.1 157804211 5625873 1089786..1089911 1 NC_009879.1 COG2003 DNA repair proteins; hypothetical protein 1089911 5625873 A1E_05295 Rickettsia canadensis str. McKiel hypothetical protein YP_001492760.1 1089786 D 293613 CDS YP_001492761.1 157804212 5625874 1090098..1091081 1 NC_009879.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1091081 5625874 A1E_05300 Rickettsia canadensis str. McKiel undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_001492761.1 1090098 D 293613 CDS YP_001492762.1 157804213 5626089 1091078..1091395 1 NC_009879.1 hypothetical protein 1091395 5626089 A1E_05305 Rickettsia canadensis str. McKiel hypothetical protein YP_001492762.1 1091078 D 293613 CDS YP_001492763.1 157804214 5626090 complement(1091857..1091955) 1 NC_009879.1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; hypothetical protein 1091955 5626090 A1E_05310 Rickettsia canadensis str. McKiel hypothetical protein YP_001492763.1 1091857 R 293613 CDS YP_001492764.1 157804215 5626091 complement(1092171..1092914) 1 NC_009879.1 COG3637 Opacity protein and related surface antigens; outer surface protein 1092914 5626091 A1E_05315 Rickettsia canadensis str. McKiel outer surface protein YP_001492764.1 1092171 R 293613 CDS YP_001492765.1 157804216 5626092 complement(1093171..1093845) 1 NC_009879.1 COG3637 Opacity protein and related surface antigens; putative outer surface protein 1093845 5626092 A1E_05320 Rickettsia canadensis str. McKiel putative outer surface protein YP_001492765.1 1093171 R 293613 CDS YP_001492766.1 157804217 5626093 complement(1094110..1094454) 1 NC_009879.1 COG1146 Ferredoxin; ferredoxin 1094454 5626093 A1E_05325 Rickettsia canadensis str. McKiel ferredoxin YP_001492766.1 1094110 R 293613 CDS YP_001492767.1 157804218 5626584 complement(1094459..1095148) 1 NC_009879.1 COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; Heme exporter protein C 1095148 5626584 A1E_05330 Rickettsia canadensis str. McKiel Heme exporter protein C YP_001492767.1 1094459 R 293613 CDS YP_001492768.1 157804219 5626585 complement(1095208..1095810) 1 NC_009879.1 COG0590 Cytosine/adenosine deaminases; cytosine deaminase 1095810 5626585 A1E_05335 Rickettsia canadensis str. McKiel cytosine deaminase YP_001492768.1 1095208 R 293613 CDS YP_001492769.1 157804220 5626586 complement(1095791..1096696) 1 NC_009879.1 COG0053 Predicted Co/Zn/Cd cation transporters; cation diffusion facilitator family transporter 1096696 5626586 A1E_05340 Rickettsia canadensis str. McKiel cation diffusion facilitator family transporter YP_001492769.1 1095791 R 293613 CDS YP_001492770.1 157804221 5626587 1096826..1097305 1 NC_009879.1 COG4520 Surface antigen; 17 kDa surface antigen precursor 1097305 5626587 A1E_05345 Rickettsia canadensis str. McKiel 17 kDa surface antigen precursor YP_001492770.1 1096826 D 293613 CDS YP_001492771.1 157804222 5626588 1097458..1097916 1 NC_009879.1 COG1881 Phospholipid-binding protein; hypothetical protein 1097916 5626588 A1E_05350 Rickettsia canadensis str. McKiel hypothetical protein YP_001492771.1 1097458 D 293613 CDS YP_001492772.1 157804223 5626589 1097921..1098622 1 NC_009879.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; methionine aminopeptidase 1098622 5626589 A1E_05355 Rickettsia canadensis str. McKiel methionine aminopeptidase YP_001492772.1 1097921 D 293613 CDS YP_001492773.1 157804224 5626828 complement(1098625..1101486) 1 NC_009879.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1101486 uvrA 5626828 uvrA Rickettsia canadensis str. McKiel excinuclease ABC subunit A YP_001492773.1 1098625 R 293613 CDS YP_001492774.1 157804225 5626829 1101595..1102053 1 NC_009879.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1102053 5626829 A1E_05365 Rickettsia canadensis str. McKiel single-stranded DNA-binding protein YP_001492774.1 1101595 D 293613 CDS YP_001492775.1 157804226 5626830 1102065..1102916 1 NC_009879.1 COG0629 Single-stranded DNA-binding protein; single-strand DNA-binding protein 1102916 5626830 A1E_05370 Rickettsia canadensis str. McKiel single-strand DNA-binding protein YP_001492775.1 1102065 D 293613 CDS YP_001492776.1 157804227 5626831 1103306..1103467 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1103467 5626831 A1E_05375 Rickettsia canadensis str. McKiel hypothetical protein YP_001492776.1 1103306 D 293613 CDS YP_001492777.1 157804228 5626833 1104065..1104382 1 NC_009879.1 COG1872 Uncharacterized conserved protein; hypothetical protein 1104382 5626833 A1E_05380 Rickettsia canadensis str. McKiel hypothetical protein YP_001492777.1 1104065 D 293613 CDS YP_001492778.1 157804229 5626686 1104562..1106433 1 NC_009879.1 molecular chaperone; heat shock protein 90 1106433 5626686 A1E_05385 Rickettsia canadensis str. McKiel heat shock protein 90 YP_001492778.1 1104562 D 293613 CDS YP_001492779.1 157804230 5626687 1106624..1107814 1 NC_009879.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 1107814 5626687 A1E_05390 Rickettsia canadensis str. McKiel 5-aminolevulinate synthase YP_001492779.1 1106624 D 293613 CDS YP_001492780.1 157804231 5626688 1108110..1109438 1 NC_009879.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1109438 tig 5626688 tig Rickettsia canadensis str. McKiel trigger factor YP_001492780.1 1108110 D 293613 CDS YP_001492781.1 157804232 5626689 complement(1109651..1110643) 1 NC_009879.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1110643 obgE 5626689 obgE Rickettsia canadensis str. McKiel GTPase ObgE YP_001492781.1 1109651 R 293613 CDS YP_001492782.1 157804233 5626690 complement(1110978..1112288) 1 NC_009879.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1112288 gltA 5626690 gltA Rickettsia canadensis str. McKiel type II citrate synthase YP_001492782.1 1110978 R 293613 CDS YP_001492783.1 157804234 5626905 complement(1112613..1112792) 1 NC_009879.1 transcriptional regulator 1112792 5626905 A1E_05410 Rickettsia canadensis str. McKiel transcriptional regulator YP_001492783.1 1112613 R 293613 CDS YP_001492784.1 157804235 5626906 complement(1113243..1113311) 1 NC_009879.1 COG0372 Citrate synthase; hypothetical protein 1113311 5626906 A1E_05415 Rickettsia canadensis str. McKiel hypothetical protein YP_001492784.1 1113243 R 293613 CDS YP_001492785.1 157804236 5626907 complement(1113589..1114377) 1 NC_009879.1 COG1573 Uracil-DNA glycosylase; N-terminus of bacteriophage-type DNA polymerase 1114377 5626907 A1E_05420 Rickettsia canadensis str. McKiel N-terminus of bacteriophage-type DNA polymerase YP_001492785.1 1113589 R 293613 CDS YP_001492786.1 157804237 5626908 1114394..1115371 1 NC_009879.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; type II citrate synthase 1115371 gltA 5626908 gltA Rickettsia canadensis str. McKiel type II citrate synthase YP_001492786.1 1114394 D 293613 CDS YP_001492787.1 157804238 5626909 1115466..1116437 1 NC_009879.1 COG2890 Methylase of polypeptide chain release factors; tRNA (guanine-N(7)-)-methyltransferase 1116437 5626909 A1E_05430 Rickettsia canadensis str. McKiel tRNA (guanine-N(7)-)-methyltransferase YP_001492787.1 1115466 D 293613 CDS YP_001492788.1 157804239 5626910 complement(1117010..1117948) 1 NC_009879.1 COG0009 Putative translation factor (SUA5); bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase 1117948 5626910 A1E_05435 Rickettsia canadensis str. McKiel bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase YP_001492788.1 1117010 R 293613 CDS YP_001492789.1 157804240 5626737 complement(1118117..1120120) 1 NC_009879.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1120120 glyS 5626737 glyS Rickettsia canadensis str. McKiel glycyl-tRNA synthetase subunit beta YP_001492789.1 1118117 R 293613 CDS YP_001492790.1 157804241 5626738 complement(1120117..1120983) 1 NC_009879.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1120983 glyQ 5626738 glyQ Rickettsia canadensis str. McKiel glycyl-tRNA synthetase subunit alpha YP_001492790.1 1120117 R 293613 CDS YP_001492791.1 157804242 5626739 complement(1121151..1121780) 1 NC_009879.1 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein 1121780 5626739 A1E_05450 Rickettsia canadensis str. McKiel hypothetical protein YP_001492791.1 1121151 R 293613 CDS YP_001492792.1 157804243 5626740 complement(1122852..1122941) 1 NC_009879.1 hypothetical protein 1122941 5626740 A1E_05465 Rickettsia canadensis str. McKiel hypothetical protein YP_001492792.1 1122852 R 293613 CDS YP_001492793.1 157804244 5626741 complement(1123125..1124078) 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1124078 5626741 A1E_05470 Rickettsia canadensis str. McKiel hypothetical protein YP_001492793.1 1123125 R 293613 CDS YP_001492794.1 157804245 5626742 complement(1124087..1124599) 1 NC_009879.1 hypothetical protein 1124599 5626742 A1E_05475 Rickettsia canadensis str. McKiel hypothetical protein YP_001492794.1 1124087 R 293613 CDS YP_001492795.1 157804246 5625927 complement(1124889..1126460) 1 NC_009879.1 COG1474 Cdc6-related protein, AAA superfamily ATPase; glycyl-tRNA synthetase subunit alpha 1126460 glyQ 5625927 glyQ Rickettsia canadensis str. McKiel glycyl-tRNA synthetase subunit alpha YP_001492795.1 1124889 R 293613 CDS YP_001492796.1 157804247 5625928 1126618..1129254 1 NC_009879.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1129254 alaS 5625928 alaS Rickettsia canadensis str. McKiel alanyl-tRNA synthetase YP_001492796.1 1126618 D 293613 CDS YP_001492797.1 157804248 5625929 complement(1129475..1130212) 1 NC_009879.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1130212 truA 5625929 truA Rickettsia canadensis str. McKiel tRNA pseudouridine synthase A YP_001492797.1 1129475 R 293613 CDS YP_001492798.1 157804249 5625930 complement(1130269..1132176) 1 NC_009879.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1132176 5625930 A1E_05495 Rickettsia canadensis str. McKiel RNA polymerase sigma factor RpoD YP_001492798.1 1130269 R 293613 CDS YP_001492799.1 157804250 5625931 complement(1132350..1134134) 1 NC_009879.1 synthesizes RNA primers at the replication forks; DNA primase 1134134 dnaG 5625931 dnaG Rickettsia canadensis str. McKiel DNA primase YP_001492799.1 1132350 R 293613 CDS YP_001492800.1 157804251 5625932 complement(1134138..1134752) 1 NC_009879.1 COG0170 Dolichol kinase; DNA primase 1134752 dnaG 5625932 dnaG Rickettsia canadensis str. McKiel DNA primase YP_001492800.1 1134138 R 293613 CDS YP_001492801.1 157804252 5626850 1135131..1135619 1 NC_009879.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1135619 greA 5626850 greA Rickettsia canadensis str. McKiel transcription elongation factor GreA YP_001492801.1 1135131 D 293613 CDS YP_001492802.1 157804253 5626851 complement(1135914..1136195) 1 NC_009879.1 NAD(P) transhydrogenase subunit alpha 1136195 5626851 A1E_05515 Rickettsia canadensis str. McKiel NAD(P) transhydrogenase subunit alpha YP_001492802.1 1135914 R 293613 CDS YP_001492803.1 157804254 5626852 complement(1136357..1136452) 1 NC_009879.1 COG3288 NAD/NADP transhydrogenase alpha subunit; hypothetical protein 1136452 5626852 A1E_05520 Rickettsia canadensis str. McKiel hypothetical protein YP_001492803.1 1136357 R 293613 CDS YP_001492804.1 157804255 5626853 1137567..1138208 1 NC_009879.1 COG2834 Outer membrane lipoprotein-sorting protein; transcription elongation factor GreA 1138208 greA 5626853 greA Rickettsia canadensis str. McKiel transcription elongation factor GreA YP_001492804.1 1137567 D 293613 CDS YP_001492805.1 157804256 5626854 1138528..1140162 1 NC_009879.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; rhe tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1140162 5626854 A1E_05545 Rickettsia canadensis str. McKiel DNA polymerase III subunits gamma and tau YP_001492805.1 1138528 D 293613 CDS YP_001492806.1 157804257 5626888 1140174..1140497 1 NC_009879.1 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 1140497 5626888 A1E_05550 Rickettsia canadensis str. McKiel hypothetical protein YP_001492806.1 1140174 D 293613 CDS YP_001492807.1 157804258 5626889 complement(1140717..1141412) 1 NC_009879.1 COG3577 Predicted aspartyl protease; hypothetical protein 1141412 5626889 A1E_05555 Rickettsia canadensis str. McKiel hypothetical protein YP_001492807.1 1140717 R 293613 CDS YP_001492808.1 157804259 5626890 complement(1141722..1142444) 1 NC_009879.1 COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein 1142444 5626890 A1E_05560 Rickettsia canadensis str. McKiel glutamine ABC transporter ATP-binding protein YP_001492808.1 1141722 R 293613 CDS YP_001492809.1 157804260 5626891 complement(1142448..1143212) 1 NC_009879.1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; hypothetical protein 1143212 5626891 A1E_05565 Rickettsia canadensis str. McKiel hypothetical protein YP_001492809.1 1142448 R 293613 CDS YP_001492810.1 157804261 5626892 1143224..1143910 1 NC_009879.1 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 1143910 5626892 A1E_05570 Rickettsia canadensis str. McKiel hypothetical protein YP_001492810.1 1143224 D 293613 CDS YP_001492811.1 157804262 5626893 1144049..1145131 1 NC_009879.1 COG0795 Predicted permeases; hypothetical protein 1145131 5626893 A1E_05575 Rickettsia canadensis str. McKiel hypothetical protein YP_001492811.1 1144049 D 293613 CDS YP_001492812.1 157804263 5626228 complement(1145134..1145598) 1 NC_009879.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 1145598 5626228 A1E_05580 Rickettsia canadensis str. McKiel DNA polymerase III subunit chi YP_001492812.1 1145134 R 293613 CDS YP_001492813.1 157804264 5626230 complement(1145881..1147035) 1 NC_009879.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1147035 5626230 A1E_05585 Rickettsia canadensis str. McKiel succinyl-diaminopimelate desuccinylase YP_001492813.1 1145881 R 293613 CDS YP_001492814.1 157804265 5626231 complement(1147271..1147408) 1 NC_009879.1 hypothetical protein 1147408 5626231 A1E_05590 Rickettsia canadensis str. McKiel hypothetical protein YP_001492814.1 1147271 R 293613 CDS YP_001492816.1 157804267 5626551 complement(1147614..1147733) 1 NC_009879.1 succinyl-diaminopimelate desuccinylase 1147733 5626551 A1E_05600 Rickettsia canadensis str. McKiel succinyl-diaminopimelate desuccinylase YP_001492816.1 1147614 R 293613 CDS YP_001492817.1 157804268 5626552 complement(1147753..1147878) 1 NC_009879.1 COG1434 Uncharacterized conserved protein; hypothetical protein 1147878 5626552 A1E_05605 Rickettsia canadensis str. McKiel hypothetical protein YP_001492817.1 1147753 R 293613 CDS YP_001492818.1 157804269 5626553 complement(1148031..1148660) 1 NC_009879.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1148660 lipB 5626553 lipB Rickettsia canadensis str. McKiel lipoate-protein ligase B YP_001492818.1 1148031 R 293613 CDS YP_001492819.1 157804270 5626554 complement(1148662..1149408) 1 NC_009879.1 COG3023 Negative regulator of beta-lactamase expression; lipoyltransferase 1149408 lipB 5626554 lipB Rickettsia canadensis str. McKiel lipoyltransferase YP_001492819.1 1148662 R 293613 CDS YP_001492820.1 157804271 5626556 complement(1149767..1150102) 1 NC_009879.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1150102 rpsP 5626556 rpsP Rickettsia canadensis str. McKiel 30S ribosomal protein S16 YP_001492820.1 1149767 R 293613 CDS YP_001492821.1 157804272 5626519 complement(1150118..1150288) 1 NC_009879.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1150288 rpmG 5626519 rpmG Rickettsia canadensis str. McKiel 50S ribosomal protein L33 YP_001492821.1 1150118 R 293613 CDS YP_001492822.1 157804273 5626520 complement(1150384..1152216) 1 NC_009879.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1152216 mutL 5626520 mutL Rickettsia canadensis str. McKiel DNA mismatch repair protein YP_001492822.1 1150384 R 293613 CDS YP_001492823.1 157804274 5626521 complement(1152213..1152377) 1 NC_009879.1 COG4391 Uncharacterized protein conserved in bacteria; hypothetical protein 1152377 5626521 A1E_05635 Rickettsia canadensis str. McKiel hypothetical protein YP_001492823.1 1152213 R 293613 CDS YP_001492824.1 157804275 5626522 1152633..1153097 1 NC_009879.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1153097 5626522 A1E_05640 Rickettsia canadensis str. McKiel oxidoreductase YP_001492824.1 1152633 D 293613 CDS YP_001492825.1 157804276 5626523 1153145..1153411 1 NC_009879.1 oxidoreductase 1153411 5626523 A1E_05645 Rickettsia canadensis str. McKiel oxidoreductase YP_001492825.1 1153145 D 293613 CDS YP_001492826.1 157804277 5626834 1153952..1154263 1 NC_009879.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); hypothetical protein 1154263 5626834 A1E_05650 Rickettsia canadensis str. McKiel hypothetical protein YP_001492826.1 1153952 D 293613 CDS YP_001492827.1 157804278 5626835 1154505..1155770 1 NC_009879.1 COG0477 Permeases of the major facilitator superfamily; DNA mismatch repair protein 1155770 mutL 5626835 mutL Rickettsia canadensis str. McKiel DNA mismatch repair protein YP_001492827.1 1154505 D 293613 CDS YP_001492828.1 157804279 5626836 1155914..1156747 1 NC_009879.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1156747 5626836 A1E_05660 Rickettsia canadensis str. McKiel coproporphyrinogen III oxidase YP_001492828.1 1155914 D 293613 CDS YP_001492829.1 157804280 5626837 complement(1156868..1157305) 1 NC_009879.1 COG1981 Predicted membrane protein; coproporphyrinogen III oxidase 1157305 5626837 A1E_05665 Rickettsia canadensis str. McKiel coproporphyrinogen III oxidase YP_001492829.1 1156868 R 293613 CDS YP_001492830.1 157804281 5626838 complement(1157317..1158360) 1 NC_009879.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1158360 hemH 5626838 hemH Rickettsia canadensis str. McKiel ferrochelatase YP_001492830.1 1157317 R 293613 CDS YP_001492831.1 157804282 5626839 complement(1158367..1159386) 1 NC_009879.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1159386 hemE 5626839 hemE Rickettsia canadensis str. McKiel uroporphyrinogen decarboxylase YP_001492831.1 1158367 R 293613 CDS