-- dump date 20140620_033319 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002844732.1 229586231 7815849 1..822 1 NC_012633.1 hypothetical protein 822 7815849 RAF_ORF0001 Rickettsia africae ESF-5 hypothetical protein YP_002844732.1 1 D 347255 CDS YP_002844733.1 229586232 7815851 1040..1357 1 NC_012633.1 Thioredoxin 1357 trxA 7815851 trxA Rickettsia africae ESF-5 Thioredoxin YP_002844733.1 1040 D 347255 CDS YP_002844734.1 229586233 7815852 1368..2117 1 NC_012633.1 O-antigen export system ATP-binding protein RfbE 2117 rfbE 7815852 rfbE Rickettsia africae ESF-5 O-antigen export system ATP-binding protein RfbE YP_002844734.1 1368 D 347255 CDS YP_002844735.1 229586234 7815853 2118..2894 1 NC_012633.1 O-antigen export system permease protein RfbA 2894 rfbA 7815853 rfbA Rickettsia africae ESF-5 O-antigen export system permease protein RfbA YP_002844735.1 2118 D 347255 CDS YP_002844736.1 229586235 7815854 2891..5992 1 NC_012633.1 undetermined function; putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase 5992 gltD 7815854 gltD Rickettsia africae ESF-5 putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase YP_002844736.1 2891 D 347255 CDS YP_002844737.1 229586236 7815855 complement(6036..6278) 1 NC_012633.1 hypothetical protein 6278 7815855 RAF_ORF0006 Rickettsia africae ESF-5 hypothetical protein YP_002844737.1 6036 R 347255 CDS YP_002844738.1 229586237 7815856 complement(6300..6581) 1 NC_012633.1 hypothetical protein 6581 7815856 RAF_ORF0007 Rickettsia africae ESF-5 hypothetical protein YP_002844738.1 6300 R 347255 CDS YP_002844739.1 229586238 7815857 complement(6612..7406) 1 NC_012633.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 7406 lpxA 7815857 lpxA Rickettsia africae ESF-5 UDP-N-acetylglucosamine acyltransferase YP_002844739.1 6612 R 347255 CDS YP_002844740.1 229586239 7815858 complement(7414..7851) 1 NC_012633.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 7851 fabZ 7815858 fabZ Rickettsia africae ESF-5 (3R)-hydroxymyristoyl-ACP dehydratase YP_002844740.1 7414 R 347255 CDS YP_002844741.1 229586240 7815859 complement(8047..9087) 1 NC_012633.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 9087 lpxD 7815859 lpxD Rickettsia africae ESF-5 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002844741.1 8047 R 347255 CDS YP_002844742.1 229586241 7815861 9920..10939 1 NC_012633.1 Putative dihydrouridine synthase Dus 10939 dus 7815861 dus Rickettsia africae ESF-5 Putative dihydrouridine synthase Dus YP_002844742.1 9920 D 347255 CDS YP_002844743.1 229586242 7815862 11287..11886 1 NC_012633.1 hypothetical protein 11886 7815862 RAF_ORF0012 Rickettsia africae ESF-5 hypothetical protein YP_002844743.1 11287 D 347255 CDS YP_002844744.1 229586243 7815863 complement(12135..12662) 1 NC_012633.1 Putative P-loop hydrolase 12662 7815863 RAF_ORF0013 Rickettsia africae ESF-5 Putative P-loop hydrolase YP_002844744.1 12135 R 347255 CDS YP_002844745.1 229586244 7815864 complement(12650..13603) 1 NC_012633.1 Zinc/manganese ABC transporter substrate binding protein 13603 znuA 7815864 znuA Rickettsia africae ESF-5 Zinc/manganese ABC transporter substrate binding protein YP_002844745.1 12650 R 347255 CDS YP_002844746.1 229586245 7815865 complement(13600..14910) 1 NC_012633.1 Poly(A) polymerase 14910 pcnB 7815865 pcnB Rickettsia africae ESF-5 Poly(A) polymerase YP_002844746.1 13600 R 347255 CDS YP_002844747.1 229586246 7815867 complement(16456..16704) 1 NC_012633.1 ComEC/Rec2 family protein 16704 7815867 RAF_ORF0018 Rickettsia africae ESF-5 ComEC/Rec2 family protein YP_002844747.1 16456 R 347255 CDS YP_002844748.1 229586247 7815868 17347..22914 1 NC_012633.1 Cell surface antigen Sca1 22914 sca1 7815868 sca1 Rickettsia africae ESF-5 Cell surface antigen Sca1 YP_002844748.1 17347 D 347255 CDS YP_002844749.1 229586248 7815870 23387..23635 1 NC_012633.1 hypothetical protein 23635 7815870 RAF_ORF0020 Rickettsia africae ESF-5 hypothetical protein YP_002844749.1 23387 D 347255 CDS YP_002844750.1 229586249 7815871 24260..24886 1 NC_012633.1 hypothetical protein 24886 7815871 RAF_ORF0021 Rickettsia africae ESF-5 hypothetical protein YP_002844750.1 24260 D 347255 CDS YP_002844751.1 229586250 7815872 complement(26098..26592) 1 NC_012633.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 26592 atpF 7815872 atpF Rickettsia africae ESF-5 F0F1 ATP synthase subunit B YP_002844751.1 26098 R 347255 CDS YP_002844752.1 229586251 7815873 complement(26592..27065) 1 NC_012633.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 27065 atpX 7815873 atpX Rickettsia africae ESF-5 F0F1 ATP synthase subunit B' YP_002844752.1 26592 R 347255 CDS YP_002844753.1 229586252 7815874 complement(27084..27308) 1 NC_012633.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 27308 atpE 7815874 atpE Rickettsia africae ESF-5 F0F1 ATP synthase subunit C YP_002844753.1 27084 R 347255 CDS YP_002844754.1 229586253 7815875 complement(27504..28232) 1 NC_012633.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 28232 atpB 7815875 atpB Rickettsia africae ESF-5 F0F1 ATP synthase subunit A YP_002844754.1 27504 R 347255 CDS YP_002844755.1 229586254 7815876 complement(28237..28500) 1 NC_012633.1 hypothetical protein 28500 7815876 RAF_ORF0026 Rickettsia africae ESF-5 hypothetical protein YP_002844755.1 28237 R 347255 CDS YP_002844756.1 229586255 7815877 complement(28611..29444) 1 NC_012633.1 Protein-disulfide isomerase 29444 dsbG 7815877 dsbG Rickettsia africae ESF-5 Protein-disulfide isomerase YP_002844756.1 28611 R 347255 CDS YP_002844757.1 229586256 7815878 29608..30129 1 NC_012633.1 Transcriptional regulator 30129 7815878 RAF_ORF0028 Rickettsia africae ESF-5 Transcriptional regulator YP_002844757.1 29608 D 347255 CDS YP_002844758.1 229586257 7815879 complement(30376..31980) 1 NC_012633.1 Putative methyltransferase 31980 7815879 RAF_ORF0029 Rickettsia africae ESF-5 Putative methyltransferase YP_002844758.1 30376 R 347255 CDS YP_002844759.1 229586258 7815880 complement(32406..33488) 1 NC_012633.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 33488 recF 7815880 recF Rickettsia africae ESF-5 recombination protein F YP_002844759.1 32406 R 347255 CDS YP_002844760.1 229586259 7815881 complement(34147..34641) 1 NC_012633.1 Dihydrofolate reductase 34641 folA 7815881 folA Rickettsia africae ESF-5 Dihydrofolate reductase YP_002844760.1 34147 R 347255 CDS YP_002844761.1 229586260 7815883 complement(36402..37070) 1 NC_012633.1 hypothetical protein 37070 7815883 RAF_ORF0035 Rickettsia africae ESF-5 hypothetical protein YP_002844761.1 36402 R 347255 CDS YP_002844762.1 229586261 7815884 complement(37128..37451) 1 NC_012633.1 hypothetical protein 37451 7815884 RAF_ORF0036 Rickettsia africae ESF-5 hypothetical protein YP_002844762.1 37128 R 347255 CDS YP_002844763.1 229586262 7815886 39932..40363 1 NC_012633.1 Sco2 protein precursor 40363 7815886 RAF_ORF0040 Rickettsia africae ESF-5 Sco2 protein precursor YP_002844763.1 39932 D 347255 CDS YP_002844764.1 229586263 7815887 complement(40539..41108) 1 NC_012633.1 hypothetical protein 41108 7815887 RAF_ORF0041 Rickettsia africae ESF-5 hypothetical protein YP_002844764.1 40539 R 347255 CDS YP_002844765.1 229586264 7815888 41174..41842 1 NC_012633.1 Putative colicin V production membrane protein 41842 cvpA 7815888 cvpA Rickettsia africae ESF-5 Putative colicin V production membrane protein YP_002844765.1 41174 D 347255 CDS YP_002844766.1 229586265 7815890 complement(43816..45138) 1 NC_012633.1 hypothetical protein 45138 7815890 RAF_ORF0045 Rickettsia africae ESF-5 hypothetical protein YP_002844766.1 43816 R 347255 CDS YP_002844767.1 229586266 7815891 complement(45148..45672) 1 NC_012633.1 hypothetical protein 45672 7815891 RAF_ORF0046 Rickettsia africae ESF-5 hypothetical protein YP_002844767.1 45148 R 347255 CDS YP_002844768.1 229586267 7815892 complement(45749..46327) 1 NC_012633.1 hypothetical protein 46327 7815892 RAF_ORF0047 Rickettsia africae ESF-5 hypothetical protein YP_002844768.1 45749 R 347255 CDS YP_002844769.1 229586268 7815893 complement(47110..47835) 1 NC_012633.1 catalyzes the conversion of 3-hydroxyacyl-CoA to 3-oxyacyl-CoA; acetoacetyl-CoA reductase 47835 phbB 7815893 phbB Rickettsia africae ESF-5 acetoacetyl-CoA reductase YP_002844769.1 47110 R 347255 CDS YP_002844770.1 229586269 7815895 49865..52438 1 NC_012633.1 chaperone ClpB 52438 clpB 7815895 clpB Rickettsia africae ESF-5 chaperone ClpB YP_002844770.1 49865 D 347255 CDS YP_002844771.1 229586270 7815896 complement(52622..53113) 1 NC_012633.1 hypothetical protein 53113 7815896 RAF_ORF0053 Rickettsia africae ESF-5 hypothetical protein YP_002844771.1 52622 R 347255 CDS YP_002844772.1 229586271 7815897 complement(53240..54274) 1 NC_012633.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 54274 gcp 7815897 gcp Rickettsia africae ESF-5 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002844772.1 53240 R 347255 CDS YP_002844773.1 229586272 7815898 complement(54457..55650) 1 NC_012633.1 Acyl-CoA desaturase 1 55650 aco1 7815898 aco1 Rickettsia africae ESF-5 Acyl-CoA desaturase 1 YP_002844773.1 54457 R 347255 CDS YP_002844774.1 229586273 7815899 complement(55798..56109) 1 NC_012633.1 Response regulator 56109 7815899 RAF_ORF0056 Rickettsia africae ESF-5 Response regulator YP_002844774.1 55798 R 347255 CDS YP_002844775.1 229586274 7815900 56531..56968 1 NC_012633.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 56968 rpsF 7815900 rpsF Rickettsia africae ESF-5 30S ribosomal protein S6 YP_002844775.1 56531 D 347255 CDS YP_002844776.1 229586275 7815901 56993..57280 1 NC_012633.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 57280 rpsR 7815901 rpsR Rickettsia africae ESF-5 30S ribosomal protein S18 YP_002844776.1 56993 D 347255 CDS YP_002844777.1 229586276 7815902 57292..57807 1 NC_012633.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 57807 rplI 7815902 rplI Rickettsia africae ESF-5 50S ribosomal protein L9 YP_002844777.1 57292 D 347255 CDS YP_002844778.1 229586277 7815903 58106..59542 1 NC_012633.1 mesJ; tRNA(Ile)-lysidine synthetase 59542 tilS 7815903 tilS Rickettsia africae ESF-5 mesJ; tRNA(Ile)-lysidine synthetase YP_002844778.1 58106 D 347255 CDS YP_002844779.1 229586278 7815904 59643..61556 1 NC_012633.1 ATP-dependent metalloprotease FtsH 61556 ftsH 7815904 ftsH Rickettsia africae ESF-5 ATP-dependent metalloprotease FtsH YP_002844779.1 59643 D 347255 CDS YP_002844780.1 229586279 7815905 61645..61842 1 NC_012633.1 Site-specific DNA methylase 61842 7815905 RAF_ORF0062 Rickettsia africae ESF-5 Site-specific DNA methylase YP_002844780.1 61645 D 347255 CDS YP_002844781.1 229586280 7815906 62463..63248 1 NC_012633.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 63248 sdhB 7815906 sdhB Rickettsia africae ESF-5 succinate dehydrogenase iron-sulfur subunit YP_002844781.1 62463 D 347255 CDS YP_002844782.1 229586281 7815907 63323..63691 1 NC_012633.1 hypothetical protein 63691 7815907 RAF_ORF0064 Rickettsia africae ESF-5 hypothetical protein YP_002844782.1 63323 D 347255 CDS YP_002844783.1 229586282 7815908 complement(63834..65054) 1 NC_012633.1 hypothetical protein 65054 7815908 RAF_ORF0065 Rickettsia africae ESF-5 hypothetical protein YP_002844783.1 63834 R 347255 CDS YP_002844784.1 229586283 7815909 complement(65033..65812) 1 NC_012633.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 65812 lgt 7815909 lgt Rickettsia africae ESF-5 prolipoprotein diacylglyceryl transferase YP_002844784.1 65033 R 347255 CDS YP_002844785.1 229586284 7815910 66057..67220 1 NC_012633.1 hypothetical protein 67220 7815910 RAF_ORF0067 Rickettsia africae ESF-5 hypothetical protein YP_002844785.1 66057 D 347255 CDS YP_002844786.1 229586285 7815911 67404..69086 1 NC_012633.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 69086 yidC 7815911 yidC Rickettsia africae ESF-5 putative inner membrane protein translocase component YidC YP_002844786.1 67404 D 347255 CDS YP_002844787.1 229586286 7815912 69086..69631 1 NC_012633.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 69631 pgsA 7815912 pgsA Rickettsia africae ESF-5 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002844787.1 69086 D 347255 CDS YP_002844788.1 229586287 7815913 complement(69709..69921) 1 NC_012633.1 hypothetical protein 69921 7815913 RAF_ORF0070 Rickettsia africae ESF-5 hypothetical protein YP_002844788.1 69709 R 347255 CDS YP_002844789.1 229586288 7815914 69965..70204 1 NC_012633.1 hypothetical protein 70204 7815914 RAF_ORF0071 Rickettsia africae ESF-5 hypothetical protein YP_002844789.1 69965 D 347255 CDS YP_002844790.1 229586289 7815915 complement(70374..70793) 1 NC_012633.1 hypothetical protein 70793 7815915 RAF_ORF0072 Rickettsia africae ESF-5 hypothetical protein YP_002844790.1 70374 R 347255 CDS YP_002844791.1 229586290 7815916 70977..71249 1 NC_012633.1 Tellurite resistance protein-related protein 71249 7815916 RAF_ORF0073 Rickettsia africae ESF-5 Tellurite resistance protein-related protein YP_002844791.1 70977 D 347255 CDS YP_002844792.1 229586291 7815917 71813..72661 1 NC_012633.1 hypothetical protein 72661 7815917 RAF_ORF0074 Rickettsia africae ESF-5 hypothetical protein YP_002844792.1 71813 D 347255 CDS YP_002844793.1 229586292 7815918 complement(72879..73553) 1 NC_012633.1 Polypeptide deformylase 73553 def3 7815918 def3 Rickettsia africae ESF-5 Polypeptide deformylase YP_002844793.1 72879 R 347255 CDS YP_002844794.1 229586293 7815919 73752..75257 1 NC_012633.1 ATP/ADP translocase 75257 tlc1 7815919 tlc1 Rickettsia africae ESF-5 ATP/ADP translocase YP_002844794.1 73752 D 347255 CDS YP_002844795.1 229586294 7815920 75316..76611 1 NC_012633.1 Sugar phosphate permease 76611 uhpC 7815920 uhpC Rickettsia africae ESF-5 Sugar phosphate permease YP_002844795.1 75316 D 347255 CDS YP_002844796.1 229586295 7815921 76636..77058 1 NC_012633.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 77058 ndk 7815921 ndk Rickettsia africae ESF-5 nucleoside diphosphate kinase YP_002844796.1 76636 D 347255 CDS YP_002844797.1 229586296 7815922 77062..78930 1 NC_012633.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 78930 gidA 7815922 gidA Rickettsia africae ESF-5 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002844797.1 77062 D 347255 CDS YP_002844798.1 229586297 7815923 78911..79489 1 NC_012633.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 79489 gidB 7815923 gidB Rickettsia africae ESF-5 16S rRNA methyltransferase GidB YP_002844798.1 78911 D 347255 CDS YP_002844799.1 229586298 7815924 79486..80253 1 NC_012633.1 chromosome partitioning ATPase 80253 soj 7815924 soj Rickettsia africae ESF-5 chromosome partitioning ATPase YP_002844799.1 79486 D 347255 CDS YP_002844800.1 229586299 7815925 80240..81100 1 NC_012633.1 ParB-like partition protein 81100 7815925 RAF_ORF0082 Rickettsia africae ESF-5 ParB-like partition protein YP_002844800.1 80240 D 347255 CDS YP_002844801.1 229586300 7815926 81358..83025 1 NC_012633.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 83025 abcT1 7815926 abcT1 Rickettsia africae ESF-5 putative ABC transporter ATP-binding protein YP_002844801.1 81358 D 347255 CDS YP_002844802.1 229586301 7815927 83028..83345 1 NC_012633.1 hypothetical protein 83345 7815927 RAF_ORF0084 Rickettsia africae ESF-5 hypothetical protein YP_002844802.1 83028 D 347255 CDS YP_002844803.1 229586302 7815928 83381..84205 1 NC_012633.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 84205 kdsA 7815928 kdsA Rickettsia africae ESF-5 2-dehydro-3-deoxyphosphooctonate aldolase YP_002844803.1 83381 D 347255 CDS YP_002844804.1 229586303 7815929 84933..85400 1 NC_012633.1 hypothetical protein 85400 7815929 RAF_ORF0086 Rickettsia africae ESF-5 hypothetical protein YP_002844804.1 84933 D 347255 CDS YP_002844805.1 229586304 7815338 complement(85967..86299) 1 NC_012633.1 Iron-sulfur cluster assembly accessory protein 86299 iscA1 7815338 iscA1 Rickettsia africae ESF-5 Iron-sulfur cluster assembly accessory protein YP_002844805.1 85967 R 347255 CDS YP_002844806.1 229586305 7815339 86529..87683 1 NC_012633.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 87683 dgt 7815339 dgt Rickettsia africae ESF-5 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_002844806.1 86529 D 347255 CDS YP_002844807.1 229586306 7815340 87835..89565 1 NC_012633.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 89565 argS 7815340 argS Rickettsia africae ESF-5 arginyl-tRNA synthetase YP_002844807.1 87835 D 347255 CDS YP_002844808.1 229586307 7815341 89738..90412 1 NC_012633.1 hypothetical protein 90412 7815341 RAF_ORF0090 Rickettsia africae ESF-5 hypothetical protein YP_002844808.1 89738 D 347255 CDS YP_002844809.1 229586308 7815342 complement(90431..90562) 1 NC_012633.1 hypothetical protein 90562 7815342 RAF_ORF0091 Rickettsia africae ESF-5 hypothetical protein YP_002844809.1 90431 R 347255 CDS YP_002844810.1 229586309 7815343 90590..92806 1 NC_012633.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 92806 parC 7815343 parC Rickettsia africae ESF-5 DNA topoisomerase IV subunit A YP_002844810.1 90590 D 347255 CDS YP_002844811.1 229586310 7815344 complement(92798..93046) 1 NC_012633.1 hypothetical protein 93046 7815344 RAF_ORF0093 Rickettsia africae ESF-5 hypothetical protein YP_002844811.1 92798 R 347255 CDS YP_002844812.1 229586311 7815345 complement(93399..94715) 1 NC_012633.1 hypothetical protein 94715 7815345 RAF_ORF0094 Rickettsia africae ESF-5 hypothetical protein YP_002844812.1 93399 R 347255 CDS YP_002844813.1 229586312 7815346 94987..95553 1 NC_012633.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 95553 dcd 7815346 dcd Rickettsia africae ESF-5 deoxycytidine triphosphate deaminase YP_002844813.1 94987 D 347255 CDS YP_002844814.1 229586313 7815347 95599..96057 1 NC_012633.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 96057 secB 7815347 secB Rickettsia africae ESF-5 preprotein translocase subunit SecB YP_002844814.1 95599 D 347255 CDS YP_002844815.1 229586314 7815348 96276..96989 1 NC_012633.1 Transcriptional activator protein CzcR 96989 czcR 7815348 czcR Rickettsia africae ESF-5 Transcriptional activator protein CzcR YP_002844815.1 96276 D 347255 CDS YP_002844816.1 229586315 7815349 96993..97814 1 NC_012633.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 97814 queF 7815349 queF Rickettsia africae ESF-5 7-cyano-7-deazaguanine reductase YP_002844816.1 96993 D 347255 CDS YP_002844817.1 229586316 7815350 complement(98059..98619) 1 NC_012633.1 hypothetical protein 98619 7815350 RAF_ORF0099 Rickettsia africae ESF-5 hypothetical protein YP_002844817.1 98059 R 347255 CDS YP_002844818.1 229586317 7815351 complement(98674..100071) 1 NC_012633.1 NAD(p) transhydrogenase subunit beta 100071 pntB 7815351 pntB Rickettsia africae ESF-5 NAD(p) transhydrogenase subunit beta YP_002844818.1 98674 R 347255 CDS YP_002844819.1 229586318 7815352 complement(100212..100946) 1 NC_012633.1 OmpW family outer-membrane protein 100946 ompW 7815352 ompW Rickettsia africae ESF-5 OmpW family outer-membrane protein YP_002844819.1 100212 R 347255 CDS YP_002844820.1 229586319 7815353 101101..101985 1 NC_012633.1 S-adenosylmethionine transporter 101985 sam 7815353 sam Rickettsia africae ESF-5 S-adenosylmethionine transporter YP_002844820.1 101101 D 347255 CDS YP_002844821.1 229586320 7815354 101972..103228 1 NC_012633.1 Proline/betaine transporter 103228 proP1 7815354 proP1 Rickettsia africae ESF-5 Proline/betaine transporter YP_002844821.1 101972 D 347255 CDS YP_002844822.1 229586321 7815356 104062..104364 1 NC_012633.1 preprotein translocase subunit SecG 104364 secG 7815356 secG Rickettsia africae ESF-5 preprotein translocase subunit SecG YP_002844822.1 104062 D 347255 CDS YP_002844823.1 229586322 7815357 complement(105266..111067) 1 NC_012633.1 Cell surface antigen Sca2 111067 sca2 7815357 sca2 Rickettsia africae ESF-5 Cell surface antigen Sca2 YP_002844823.1 105266 R 347255 CDS YP_002844824.1 229586323 7815358 111304..112683 1 NC_012633.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 112683 cysS 7815358 cysS Rickettsia africae ESF-5 cysteinyl-tRNA synthetase YP_002844824.1 111304 D 347255 CDS YP_002844825.1 229586324 7815359 112930..113817 1 NC_012633.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 113817 rpsB 7815359 rpsB Rickettsia africae ESF-5 30S ribosomal protein S2 YP_002844825.1 112930 D 347255 CDS YP_002844826.1 229586325 7815360 114014..114943 1 NC_012633.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 114943 tsf 7815360 tsf Rickettsia africae ESF-5 elongation factor Ts YP_002844826.1 114014 D 347255 CDS YP_002844827.1 229586326 7815361 115416..115748 1 NC_012633.1 hypothetical protein 115748 7815361 RAF_ORF0109 Rickettsia africae ESF-5 hypothetical protein YP_002844827.1 115416 D 347255 CDS YP_002844828.1 229586327 7815362 complement(116460..117854) 1 NC_012633.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 117854 kdtA 7815362 kdtA Rickettsia africae ESF-5 3-deoxy-D-manno-octulosonic-acid transferase YP_002844828.1 116460 R 347255 CDS YP_002844829.1 229586328 7815363 complement(117851..118507) 1 NC_012633.1 hypothetical protein 118507 7815363 RAF_ORF0111 Rickettsia africae ESF-5 hypothetical protein YP_002844829.1 117851 R 347255 CDS YP_002844830.1 229586329 7815364 complement(118658..119863) 1 NC_012633.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 119863 aatA 7815364 aatA Rickettsia africae ESF-5 aspartate aminotransferase YP_002844830.1 118658 R 347255 CDS YP_002844831.1 229586330 7815365 120524..121528 1 NC_012633.1 hypothetical protein 121528 7815365 RAF_ORF0113 Rickettsia africae ESF-5 hypothetical protein YP_002844831.1 120524 D 347255 CDS YP_002844832.1 229586331 7815366 121533..122288 1 NC_012633.1 VacJ lipoprotein precursor 122288 vacJ 7815366 vacJ Rickettsia africae ESF-5 VacJ lipoprotein precursor YP_002844832.1 121533 D 347255 CDS YP_002844833.1 229586332 7815367 122308..122907 1 NC_012633.1 ABC-type transporter related to toluene tolerance 122907 7815367 RAF_ORF0115 Rickettsia africae ESF-5 ABC-type transporter related to toluene tolerance YP_002844833.1 122308 D 347255 CDS YP_002844834.1 229586333 7815369 124151..125218 1 NC_012633.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 125218 alr 7815369 alr Rickettsia africae ESF-5 alanine racemase YP_002844834.1 124151 D 347255 CDS YP_002844835.1 229586334 7815370 125364..126143 1 NC_012633.1 ABC transporter permease 126143 7815370 RAF_ORF0119 Rickettsia africae ESF-5 ABC transporter permease YP_002844835.1 125364 D 347255 CDS YP_002844836.1 229586335 7815371 126297..127052 1 NC_012633.1 Ribonucleotide ABC transporter ATP-binding protein 127052 mkl 7815371 mkl Rickettsia africae ESF-5 Ribonucleotide ABC transporter ATP-binding protein YP_002844836.1 126297 D 347255 CDS YP_002844837.1 229586336 7815372 127054..127302 1 NC_012633.1 hypothetical protein 127302 7815372 RAF_ORF0121 Rickettsia africae ESF-5 hypothetical protein YP_002844837.1 127054 D 347255 CDS YP_002844838.1 229586337 7815373 complement(127867..128163) 1 NC_012633.1 hypothetical protein 128163 7815373 RAF_ORF0122 Rickettsia africae ESF-5 hypothetical protein YP_002844838.1 127867 R 347255 CDS YP_002844839.1 229586338 7815374 complement(128471..128842) 1 NC_012633.1 hypothetical protein 128842 7815374 RAF_ORF0123 Rickettsia africae ESF-5 hypothetical protein YP_002844839.1 128471 R 347255 CDS YP_002844840.1 229586339 7815375 129752..130045 1 NC_012633.1 required for 70S ribosome assembly; 50S ribosomal protein L28 130045 rpmB 7815375 rpmB Rickettsia africae ESF-5 50S ribosomal protein L28 YP_002844840.1 129752 D 347255 CDS YP_002844841.1 229586340 7815376 130042..130278 1 NC_012633.1 RpmE; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 130278 rpmE 7815376 rpmE Rickettsia africae ESF-5 50S ribosomal protein L31 YP_002844841.1 130042 D 347255 CDS YP_002844842.1 229586341 7815378 130886..131524 1 NC_012633.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 131524 engB 7815378 engB Rickettsia africae ESF-5 ribosome biogenesis GTP-binding protein YsxC YP_002844842.1 130886 D 347255 CDS YP_002844843.1 229586342 7815379 131472..132395 1 NC_012633.1 Acetylglutamate kinase 132395 argB 7815379 argB Rickettsia africae ESF-5 Acetylglutamate kinase YP_002844843.1 131472 D 347255 CDS YP_002844844.1 229586343 7815380 132408..132695 1 NC_012633.1 type IV secretion system protein VirB3 132695 virB3 7815380 virB3 Rickettsia africae ESF-5 type IV secretion system protein VirB3 YP_002844844.1 132408 D 347255 CDS YP_002844845.1 229586344 7815381 132785..135202 1 NC_012633.1 type IV secretion system ATPase VirB4 135202 virB4-1 7815381 virB4-1 Rickettsia africae ESF-5 type IV secretion system ATPase VirB4 YP_002844845.1 132785 D 347255 CDS YP_002844846.1 229586345 7815382 135320..138439 1 NC_012633.1 VirB6 138439 virB6-1 7815382 virB6-1 Rickettsia africae ESF-5 VirB6 YP_002844846.1 135320 D 347255 CDS YP_002844847.1 229586346 7815384 140419..143319 1 NC_012633.1 VirB6 143319 virB6-3 7815384 virB6-3 Rickettsia africae ESF-5 VirB6 YP_002844847.1 140419 D 347255 CDS YP_002844848.1 229586347 7815385 143493..146168 1 NC_012633.1 VirB6 146168 virB6-4 7815385 virB6-4 Rickettsia africae ESF-5 VirB6 YP_002844848.1 143493 D 347255 CDS YP_002844849.1 229586348 7815386 146321..149782 1 NC_012633.1 VirB6 149782 virB6-5 7815386 virB6-5 Rickettsia africae ESF-5 VirB6 YP_002844849.1 146321 D 347255 CDS YP_002844850.1 229586349 7815389 153126..153830 1 NC_012633.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 153830 trmD 7815389 trmD Rickettsia africae ESF-5 tRNA (guanine-N(1)-)-methyltransferase YP_002844850.1 153126 D 347255 CDS YP_002844851.1 229586350 7815390 153848..154264 1 NC_012633.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 154264 rplS 7815390 rplS Rickettsia africae ESF-5 50S ribosomal protein L19 YP_002844851.1 153848 D 347255 CDS YP_002844852.1 229586351 7815391 complement(154434..154670) 1 NC_012633.1 hypothetical protein 154670 7815391 RAF_ORF0142 Rickettsia africae ESF-5 hypothetical protein YP_002844852.1 154434 R 347255 CDS YP_002844853.1 229586352 7815392 154743..155669 1 NC_012633.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 155669 secF 7815392 secF Rickettsia africae ESF-5 preprotein translocase subunit SecF YP_002844853.1 154743 D 347255 CDS YP_002844854.1 229586353 7815393 155834..157099 1 NC_012633.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 157099 nuoF 7815393 nuoF Rickettsia africae ESF-5 NADH dehydrogenase I subunit F YP_002844854.1 155834 D 347255 CDS YP_002844855.1 229586354 7815394 157283..158083 1 NC_012633.1 Signal peptidase I 158083 lepB 7815394 lepB Rickettsia africae ESF-5 Signal peptidase I YP_002844855.1 157283 D 347255 CDS YP_002844856.1 229586355 7815395 158083..158766 1 NC_012633.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 158766 rnc 7815395 rnc Rickettsia africae ESF-5 ribonuclease III YP_002844856.1 158083 D 347255 CDS YP_002844857.1 229586356 7815396 158759..159778 1 NC_012633.1 GTP-binding protein Era 159778 era 7815396 era Rickettsia africae ESF-5 GTP-binding protein Era YP_002844857.1 158759 D 347255 CDS YP_002844858.1 229586357 7815397 159895..160368 1 NC_012633.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 160368 ruvC 7815397 ruvC Rickettsia africae ESF-5 Holliday junction resolvase YP_002844858.1 159895 D 347255 CDS YP_002844859.1 229586358 7815398 160370..161062 1 NC_012633.1 tRNA/rRNA methyltransferase 161062 7815398 RAF_ORF0149 Rickettsia africae ESF-5 tRNA/rRNA methyltransferase YP_002844859.1 160370 D 347255 CDS YP_002844860.1 229586359 7815399 complement(161043..161648) 1 NC_012633.1 nucleotidyltransferase substrate binding protein 161648 7815399 RAF_ORF0150 Rickettsia africae ESF-5 nucleotidyltransferase substrate binding protein YP_002844860.1 161043 R 347255 CDS YP_002844861.1 229586360 7815400 complement(161708..162754) 1 NC_012633.1 Putative nucleoside-diphosphate-sugar epimerase 162754 7815400 RAF_ORF0151 Rickettsia africae ESF-5 Putative nucleoside-diphosphate-sugar epimerase YP_002844861.1 161708 R 347255 CDS YP_002844862.1 229586361 7815401 complement(162751..163710) 1 NC_012633.1 hypothetical protein 163710 mrp 7815401 mrp Rickettsia africae ESF-5 hypothetical protein YP_002844862.1 162751 R 347255 CDS YP_002844863.1 229586362 7815402 163815..164855 1 NC_012633.1 Protease activity modulator HflK 164855 hflK 7815402 hflK Rickettsia africae ESF-5 Protease activity modulator HflK YP_002844863.1 163815 D 347255 CDS YP_002844864.1 229586363 7815403 164948..165808 1 NC_012633.1 Membrane protease subunit, stomatin/prohibitin-like protein 165808 hflC2 7815403 hflC2 Rickettsia africae ESF-5 Membrane protease subunit, stomatin/prohibitin-like protein YP_002844864.1 164948 D 347255 CDS YP_002844865.1 229586364 7815404 165846..167324 1 NC_012633.1 Periplasmic serine protease 167324 htrA 7815404 htrA Rickettsia africae ESF-5 Periplasmic serine protease YP_002844865.1 165846 D 347255 CDS YP_002844866.1 229586365 7815405 167501..168244 1 NC_012633.1 hypothetical protein 168244 7815405 RAF_ORF0156 Rickettsia africae ESF-5 hypothetical protein YP_002844866.1 167501 D 347255 CDS YP_002844867.1 229586366 7815406 168411..168785 1 NC_012633.1 Succinate dehydrogenase cytochrome b-556 subunit 168785 sdhC 7815406 sdhC Rickettsia africae ESF-5 Succinate dehydrogenase cytochrome b-556 subunit YP_002844867.1 168411 D 347255 CDS YP_002844868.1 229586367 7815407 168930..169310 1 NC_012633.1 Succinate dehydrogenase hydrophobic membrane anchor protein 169310 sdhD 7815407 sdhD Rickettsia africae ESF-5 Succinate dehydrogenase hydrophobic membrane anchor protein YP_002844868.1 168930 D 347255 CDS YP_002844869.1 229586368 7815408 169444..171234 1 NC_012633.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 171234 sdhA 7815408 sdhA Rickettsia africae ESF-5 succinate dehydrogenase flavoprotein subunit YP_002844869.1 169444 D 347255 CDS YP_002844870.1 229586369 7815409 171382..172038 1 NC_012633.1 amino acid ABC transporter permease 172038 yqiY 7815409 yqiY Rickettsia africae ESF-5 amino acid ABC transporter permease YP_002844870.1 171382 D 347255 CDS YP_002844871.1 229586370 7815410 172199..172588 1 NC_012633.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 172588 rpsL 7815410 rpsL Rickettsia africae ESF-5 30S ribosomal protein S12 YP_002844871.1 172199 D 347255 CDS YP_002844872.1 229586371 7815411 172615..173097 1 NC_012633.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 173097 rpsG 7815411 rpsG Rickettsia africae ESF-5 30S ribosomal protein S7 YP_002844872.1 172615 D 347255 CDS YP_002844873.1 229586372 7815412 173109..175208 1 NC_012633.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 175208 fusA 7815412 fusA Rickettsia africae ESF-5 elongation factor G YP_002844873.1 173109 D 347255 CDS YP_002844874.1 229586373 7815414 175628..175828 1 NC_012633.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 175828 secE 7815414 secE Rickettsia africae ESF-5 preprotein translocase subunit SecE YP_002844874.1 175628 D 347255 CDS YP_002844875.1 229586374 7815415 175844..176422 1 NC_012633.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 176422 nusG 7815415 nusG Rickettsia africae ESF-5 transcription antitermination protein NusG YP_002844875.1 175844 D 347255 CDS YP_002844876.1 229586375 7815416 176694..177131 1 NC_012633.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 177131 rplK 7815416 rplK Rickettsia africae ESF-5 50S ribosomal protein L11 YP_002844876.1 176694 D 347255 CDS YP_002844877.1 229586376 7815417 177137..177856 1 NC_012633.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 177856 rplA 7815417 rplA Rickettsia africae ESF-5 50S ribosomal protein L1 YP_002844877.1 177137 D 347255 CDS YP_002844878.1 229586377 7815176 177967..178476 1 NC_012633.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 178476 rplJ 7815176 rplJ Rickettsia africae ESF-5 50S ribosomal protein L10 YP_002844878.1 177967 D 347255 CDS YP_002844879.1 229586378 7815177 178676..179053 1 NC_012633.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 179053 rplL 7815177 rplL Rickettsia africae ESF-5 50S ribosomal protein L7/L12 YP_002844879.1 178676 D 347255 CDS YP_002844880.1 229586379 7815178 179998..184119 1 NC_012633.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 184119 rpoB 7815178 rpoB Rickettsia africae ESF-5 DNA-directed RNA polymerase subunit beta YP_002844880.1 179998 D 347255 CDS YP_002844881.1 229586380 7815179 184377..188495 1 NC_012633.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 188495 rpoC 7815179 rpoC Rickettsia africae ESF-5 DNA-directed RNA polymerase subunit beta' YP_002844881.1 184377 D 347255 CDS YP_002844882.1 229586381 7815180 complement(188902..190071) 1 NC_012633.1 hypothetical protein 190071 7815180 RAF_ORF0172 Rickettsia africae ESF-5 hypothetical protein YP_002844882.1 188902 R 347255 CDS YP_002844883.1 229586382 7815181 190240..191742 1 NC_012633.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 191742 pepA 7815181 pepA Rickettsia africae ESF-5 leucyl aminopeptidase YP_002844883.1 190240 D 347255 CDS YP_002844884.1 229586383 7815182 191961..192761 1 NC_012633.1 Chromosome partitioning protein-like protein 192761 7815182 RAF_ORF0174 Rickettsia africae ESF-5 Chromosome partitioning protein-like protein YP_002844884.1 191961 D 347255 CDS YP_002844885.1 229586384 7815183 192844..193278 1 NC_012633.1 hypothetical protein 193278 7815183 RAF_ORF0175 Rickettsia africae ESF-5 hypothetical protein YP_002844885.1 192844 D 347255 CDS YP_002844886.1 229586385 7815184 193369..195177 1 NC_012633.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 195177 aspS 7815184 aspS Rickettsia africae ESF-5 aspartyl-tRNA synthetase YP_002844886.1 193369 D 347255 CDS YP_002844887.1 229586386 7815185 complement(195455..197569) 1 NC_012633.1 hypothetical protein 197569 7815185 RAF_ORF0177 Rickettsia africae ESF-5 hypothetical protein YP_002844887.1 195455 R 347255 CDS YP_002844888.1 229586387 7815186 complement(197953..198663) 1 NC_012633.1 Integral membrane protein, interacts with FtsH 198663 7815186 RAF_ORF0178 Rickettsia africae ESF-5 Integral membrane protein, interacts with FtsH YP_002844888.1 197953 R 347255 CDS YP_002844889.1 229586388 7815187 complement(198737..199456) 1 NC_012633.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 199456 dapB 7815187 dapB Rickettsia africae ESF-5 dihydrodipicolinate reductase YP_002844889.1 198737 R 347255 CDS YP_002844890.1 229586389 7815188 complement(199478..199957) 1 NC_012633.1 Flavoprotein oxygenase DIM6/NTAB family protein 199957 7815188 RAF_ORF0180 Rickettsia africae ESF-5 Flavoprotein oxygenase DIM6/NTAB family protein YP_002844890.1 199478 R 347255 CDS YP_002844891.1 229586390 7815189 complement(199942..200667) 1 NC_012633.1 amino acid ABC transporter substrate-binding protein 200667 yqiX 7815189 yqiX Rickettsia africae ESF-5 amino acid ABC transporter substrate-binding protein YP_002844891.1 199942 R 347255 CDS YP_002844892.1 229586391 7815190 complement(200878..202329) 1 NC_012633.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 202329 gatB 7815190 gatB Rickettsia africae ESF-5 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002844892.1 200878 R 347255 CDS YP_002844893.1 229586392 7815191 complement(202332..203813) 1 NC_012633.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 203813 gatA 7815191 gatA Rickettsia africae ESF-5 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002844893.1 202332 R 347255 CDS YP_002844894.1 229586393 7815192 complement(203816..204118) 1 NC_012633.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 204118 gatC 7815192 gatC Rickettsia africae ESF-5 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002844894.1 203816 R 347255 CDS YP_002844895.1 229586394 7815193 complement(204420..204593) 1 NC_012633.1 hypothetical protein 204593 7815193 RAF_ORF0185 Rickettsia africae ESF-5 hypothetical protein YP_002844895.1 204420 R 347255 CDS YP_002844896.1 229586395 7815194 complement(204908..205468) 1 NC_012633.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 205468 frr 7815194 frr Rickettsia africae ESF-5 ribosome recycling factor YP_002844896.1 204908 R 347255 CDS YP_002844897.1 229586396 7815195 complement(205757..206485) 1 NC_012633.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 206485 pyrH 7815195 pyrH Rickettsia africae ESF-5 uridylate kinase YP_002844897.1 205757 R 347255 CDS YP_002844898.1 229586397 7815196 complement(206494..206817) 1 NC_012633.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E 206817 mnhE 7815196 mnhE Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit E YP_002844898.1 206494 R 347255 CDS YP_002844899.1 229586398 7815197 complement(206801..208360) 1 NC_012633.1 MFS-type multidrug resistance protein B 208360 emrB 7815197 emrB Rickettsia africae ESF-5 MFS-type multidrug resistance protein B YP_002844899.1 206801 R 347255 CDS YP_002844900.1 229586399 7815198 208592..208795 1 NC_012633.1 hypothetical protein 208795 7815198 RAF_ORF0190 Rickettsia africae ESF-5 hypothetical protein YP_002844900.1 208592 D 347255 CDS YP_002844901.1 229586400 7815199 complement(209171..209419) 1 NC_012633.1 hypothetical protein 209419 7815199 RAF_ORF0191 Rickettsia africae ESF-5 hypothetical protein YP_002844901.1 209171 R 347255 CDS YP_002844902.1 229586401 7815200 complement(209421..210008) 1 NC_012633.1 hypothetical protein 210008 7815200 RAF_ORF0192 Rickettsia africae ESF-5 hypothetical protein YP_002844902.1 209421 R 347255 CDS YP_002844903.1 229586402 7815202 complement(210706..213012) 1 NC_012633.1 Outer membrane protein omp1 213012 omp1 7815202 omp1 Rickettsia africae ESF-5 Outer membrane protein omp1 YP_002844903.1 210706 R 347255 CDS YP_002844904.1 229586403 7815203 complement(213251..214324) 1 NC_012633.1 Putative membrane-associated zinc metalloprotease 214324 7815203 RAF_ORF0194 Rickettsia africae ESF-5 Putative membrane-associated zinc metalloprotease YP_002844904.1 213251 R 347255 CDS YP_002844905.1 229586404 7815204 214606..215076 1 NC_012633.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 215076 nusB 7815204 nusB Rickettsia africae ESF-5 transcription antitermination protein NusB YP_002844905.1 214606 D 347255 CDS YP_002844906.1 229586405 7815205 215211..215894 1 NC_012633.1 Ribosomal RNA large subunit methyltransferase J 215894 rrmJ 7815205 rrmJ Rickettsia africae ESF-5 Ribosomal RNA large subunit methyltransferase J YP_002844906.1 215211 D 347255 CDS YP_002844907.1 229586406 7815206 complement(215945..217006) 1 NC_012633.1 hypothetical protein 217006 7815206 RAF_ORF0197 Rickettsia africae ESF-5 hypothetical protein YP_002844907.1 215945 R 347255 CDS YP_002844908.1 229586407 7815207 217171..218124 1 NC_012633.1 hypothetical protein 218124 7815207 RAF_ORF0198 Rickettsia africae ESF-5 hypothetical protein YP_002844908.1 217171 D 347255 CDS YP_002844909.1 229586408 7815208 complement(218183..218623) 1 NC_012633.1 Oligoketide cyclase/lipid transport protein 218623 7815208 RAF_ORF0199 Rickettsia africae ESF-5 Oligoketide cyclase/lipid transport protein YP_002844909.1 218183 R 347255 CDS YP_002844910.1 229586409 7815209 complement(218623..218904) 1 NC_012633.1 hypothetical protein 218904 7815209 RAF_ORF0200 Rickettsia africae ESF-5 hypothetical protein YP_002844910.1 218623 R 347255 CDS YP_002844911.1 229586410 7815210 218917..219657 1 NC_012633.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 219657 7815210 RAF_ORF0201 Rickettsia africae ESF-5 16S ribosomal RNA methyltransferase RsmE YP_002844911.1 218917 D 347255 CDS YP_002844912.1 229586411 7815211 complement(219739..219975) 1 NC_012633.1 hypothetical protein 219975 7815211 RAF_ORF0202 Rickettsia africae ESF-5 hypothetical protein YP_002844912.1 219739 R 347255 CDS YP_002844913.1 229586412 7815212 complement(220230..223256) 1 NC_012633.1 Hydrophobe/amphiphile efflux-1 (HAE1) family protein 223256 acrF 7815212 acrF Rickettsia africae ESF-5 Hydrophobe/amphiphile efflux-1 (HAE1) family protein YP_002844913.1 220230 R 347255 CDS YP_002844914.1 229586413 7815213 223648..224064 1 NC_012633.1 DNA-binding protein HU 224064 hupA 7815213 hupA Rickettsia africae ESF-5 DNA-binding protein HU YP_002844914.1 223648 D 347255 CDS YP_002844915.1 229586414 7815214 224219..225013 1 NC_012633.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 225013 holB 7815214 holB Rickettsia africae ESF-5 DNA polymerase III subunit delta' YP_002844915.1 224219 D 347255 CDS YP_002844916.1 229586415 7815215 225220..226569 1 NC_012633.1 Signal recognition particle protein 226569 ffh 7815215 ffh Rickettsia africae ESF-5 Signal recognition particle protein YP_002844916.1 225220 D 347255 CDS YP_002844917.1 229586416 7815217 229311..230513 1 NC_012633.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 230513 hemN 7815217 hemN Rickettsia africae ESF-5 coproporphyrinogen III oxidase YP_002844917.1 229311 D 347255 CDS YP_002844918.1 229586417 7815218 230735..231121 1 NC_012633.1 Ankyrin repeat protein 231121 7815218 RAF_ORF0213 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002844918.1 230735 D 347255 CDS YP_002844919.1 229586418 7815219 complement(231661..231993) 1 NC_012633.1 cephalosporin hydroxylase 231993 cmcI 7815219 cmcI Rickettsia africae ESF-5 cephalosporin hydroxylase YP_002844919.1 231661 R 347255 CDS YP_002844920.1 229586419 7815220 complement(232426..233625) 1 NC_012633.1 Na+/H+-dicarboxylate symporter 233625 gltP 7815220 gltP Rickettsia africae ESF-5 Na+/H+-dicarboxylate symporter YP_002844920.1 232426 R 347255 CDS YP_002844921.1 229586420 7815221 complement(233666..233980) 1 NC_012633.1 Periplasmic divalent cation tolerance protein 233980 cutA 7815221 cutA Rickettsia africae ESF-5 Periplasmic divalent cation tolerance protein YP_002844921.1 233666 R 347255 CDS YP_002844922.1 229586421 7815222 complement(233983..234501) 1 NC_012633.1 6-pyruvoyl-tetrahydropterin synthase 234501 7815222 RAF_ORF0217 Rickettsia africae ESF-5 6-pyruvoyl-tetrahydropterin synthase YP_002844922.1 233983 R 347255 CDS YP_002844923.1 229586422 7815223 complement(234569..235756) 1 NC_012633.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 235756 sucB 7815223 sucB Rickettsia africae ESF-5 dihydrolipoamide succinyltransferase YP_002844923.1 234569 R 347255 CDS YP_002844924.1 229586423 7815224 complement(235921..238707) 1 NC_012633.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 238707 sucA 7815224 sucA Rickettsia africae ESF-5 2-oxoglutarate dehydrogenase E1 component YP_002844924.1 235921 R 347255 CDS YP_002844925.1 229586424 7815225 complement(238841..240331) 1 NC_012633.1 Thermostable carboxypeptidase 240331 7815225 RAF_ORF0220 Rickettsia africae ESF-5 Thermostable carboxypeptidase YP_002844925.1 238841 R 347255 CDS YP_002844926.1 229586425 7815226 complement(240508..242145) 1 NC_012633.1 DNA repair protein RecN 242145 recN 7815226 recN Rickettsia africae ESF-5 DNA repair protein RecN YP_002844926.1 240508 R 347255 CDS YP_002844927.1 229586426 7815227 complement(242153..242908) 1 NC_012633.1 DNA uptake lipoprotein 242908 comL 7815227 comL Rickettsia africae ESF-5 DNA uptake lipoprotein YP_002844927.1 242153 R 347255 CDS YP_002844928.1 229586427 7815228 complement(243149..243310) 1 NC_012633.1 Cation transport regulator ChaB 243310 chaB 7815228 chaB Rickettsia africae ESF-5 Cation transport regulator ChaB YP_002844928.1 243149 R 347255 CDS YP_002844929.1 229586428 7815229 complement(243447..244568) 1 NC_012633.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 244568 dnaJ 7815229 dnaJ Rickettsia africae ESF-5 chaperone protein DnaJ YP_002844929.1 243447 R 347255 CDS YP_002844930.1 229586429 7815230 complement(244697..246580) 1 NC_012633.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 246580 dnaK 7815230 dnaK Rickettsia africae ESF-5 molecular chaperone DnaK YP_002844930.1 244697 R 347255 CDS YP_002844931.1 229586430 7815231 246644..248137 1 NC_012633.1 Heat shock protease 248137 7815231 RAF_ORF0226 Rickettsia africae ESF-5 Heat shock protease YP_002844931.1 246644 D 347255 CDS YP_002844932.1 229586431 7815232 complement(249297..249644) 1 NC_012633.1 hypothetical protein 249644 7815232 RAF_ORF0227 Rickettsia africae ESF-5 hypothetical protein YP_002844932.1 249297 R 347255 CDS YP_002844933.1 229586432 7815233 249813..250286 1 NC_012633.1 hypothetical protein 250286 7815233 RAF_ORF0228 Rickettsia africae ESF-5 hypothetical protein YP_002844933.1 249813 D 347255 CDS YP_002844934.1 229586433 7815234 250294..251268 1 NC_012633.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 251268 holA 7815234 holA Rickettsia africae ESF-5 DNA polymerase III subunit delta YP_002844934.1 250294 D 347255 CDS YP_002844935.1 229586434 7815235 251416..251955 1 NC_012633.1 Ubiquinone biosynthesis protein coq7 251955 coq7 7815235 coq7 Rickettsia africae ESF-5 Ubiquinone biosynthesis protein coq7 YP_002844935.1 251416 D 347255 CDS YP_002844936.1 229586435 7815236 252431..253357 1 NC_012633.1 Cytochrome c oxidase subunit III 253357 coxC 7815236 coxC Rickettsia africae ESF-5 Cytochrome c oxidase subunit III YP_002844936.1 252431 D 347255 CDS YP_002844937.1 229586436 7815237 253513..253869 1 NC_012633.1 VirB2-like protein 253869 virB2 7815237 virB2 Rickettsia africae ESF-5 VirB2-like protein YP_002844937.1 253513 D 347255 CDS YP_002844938.1 229586437 7815238 complement(254213..254851) 1 NC_012633.1 hypothetical protein 254851 7815238 RAF_ORF0233 Rickettsia africae ESF-5 hypothetical protein YP_002844938.1 254213 R 347255 CDS YP_002844939.1 229586438 7815239 254927..255751 1 NC_012633.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 255751 dapD 7815239 dapD Rickettsia africae ESF-5 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002844939.1 254927 D 347255 CDS YP_002844940.1 229586439 7815241 complement(257804..260062) 1 NC_012633.1 Bifunctional penicillin-binding protein 1C 260062 pbpC 7815241 pbpC Rickettsia africae ESF-5 Bifunctional penicillin-binding protein 1C YP_002844940.1 257804 R 347255 CDS YP_002844941.1 229586440 7815243 complement(265202..265648) 1 NC_012633.1 Universal stress protein UspA-like nucleotide-binding protein 265648 uspA 7815243 uspA Rickettsia africae ESF-5 Universal stress protein UspA-like nucleotide-binding protein YP_002844941.1 265202 R 347255 CDS YP_002844942.1 229586441 7815244 complement(265658..266599) 1 NC_012633.1 TRAP-type transport system, periplasmic protein 266599 imp 7815244 imp Rickettsia africae ESF-5 TRAP-type transport system, periplasmic protein YP_002844942.1 265658 R 347255 CDS YP_002844943.1 229586442 7815245 complement(266604..267674) 1 NC_012633.1 hypothetical protein 267674 7815245 RAF_ORF0243 Rickettsia africae ESF-5 hypothetical protein YP_002844943.1 266604 R 347255 CDS YP_002844944.1 229586443 7815246 complement(267687..268025) 1 NC_012633.1 Ferredoxin 268025 fdxB 7815246 fdxB Rickettsia africae ESF-5 Ferredoxin YP_002844944.1 267687 R 347255 CDS YP_002844945.1 229586444 7815247 complement(268089..269876) 1 NC_012633.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 269876 hscA 7815247 hscA Rickettsia africae ESF-5 chaperone protein HscA YP_002844945.1 268089 R 347255 CDS YP_002844946.1 229586445 7815248 complement(269867..270367) 1 NC_012633.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 270367 hscB 7815248 hscB Rickettsia africae ESF-5 co-chaperone HscB YP_002844946.1 269867 R 347255 CDS YP_002844947.1 229586446 7815249 270429..271010 1 NC_012633.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 271010 rnhB 7815249 rnhB Rickettsia africae ESF-5 ribonuclease HII YP_002844947.1 270429 D 347255 CDS YP_002844948.1 229586447 7815250 complement(271164..273149) 1 NC_012633.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 273149 uvrB 7815250 uvrB Rickettsia africae ESF-5 excinuclease ABC subunit B YP_002844948.1 271164 R 347255 CDS YP_002844949.1 229586448 7815251 273220..273528 1 NC_012633.1 Glutaredoxin, GrxC family 273528 grxC1 7815251 grxC1 Rickettsia africae ESF-5 Glutaredoxin, GrxC family YP_002844949.1 273220 D 347255 CDS YP_002844950.1 229586449 7815253 276521..279238 1 NC_012633.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 279238 gyrA 7815253 gyrA Rickettsia africae ESF-5 DNA gyrase subunit A YP_002844950.1 276521 D 347255 CDS YP_002844951.1 229586450 7815255 281251..281436 1 NC_012633.1 hypothetical protein 281436 7815255 RAF_ORF0256 Rickettsia africae ESF-5 hypothetical protein YP_002844951.1 281251 D 347255 CDS YP_002844952.1 229586451 7815850 281890..282417 1 NC_012633.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 282417 def 7815850 def Rickettsia africae ESF-5 peptide deformylase YP_002844952.1 281890 D 347255 CDS YP_002844953.1 229586452 7815258 282414..283325 1 NC_012633.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 283325 fmt 7815258 fmt Rickettsia africae ESF-5 methionyl-tRNA formyltransferase YP_002844953.1 282414 D 347255 CDS YP_002844954.1 229586453 7815259 283495..283911 1 NC_012633.1 hypothetical protein 283911 7815259 RAF_ORF0259 Rickettsia africae ESF-5 hypothetical protein YP_002844954.1 283495 D 347255 CDS YP_002844955.1 229586454 7815263 complement(288457..289509) 1 NC_012633.1 Putative ATPase n2B 289509 n2B 7815263 n2B Rickettsia africae ESF-5 Putative ATPase n2B YP_002844955.1 288457 R 347255 CDS YP_002844956.1 229586455 7815264 complement(289724..290821) 1 NC_012633.1 S-adenosylmethionine--tRNA ribosyltransferase-isomerase 290821 queA 7815264 queA Rickettsia africae ESF-5 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002844956.1 289724 R 347255 CDS YP_002844957.1 229586456 7815265 291057..291338 1 NC_012633.1 Ankyrin repeat protein 291338 7815265 RAF_ORF0264 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002844957.1 291057 D 347255 CDS YP_002844958.1 229586457 7815266 291728..292120 1 NC_012633.1 hypothetical protein 292120 7815266 RAF_ORF0265 Rickettsia africae ESF-5 hypothetical protein YP_002844958.1 291728 D 347255 CDS YP_002844959.1 229586458 7815267 complement(292188..293957) 1 NC_012633.1 Multidrug resistance ABC transporter ATP-binding protein 293957 abcT3 7815267 abcT3 Rickettsia africae ESF-5 Multidrug resistance ABC transporter ATP-binding protein YP_002844959.1 292188 R 347255 CDS YP_002844960.1 229586459 7815268 294138..294410 1 NC_012633.1 hypothetical protein 294410 7815268 RAF_ORF0267 Rickettsia africae ESF-5 hypothetical protein YP_002844960.1 294138 D 347255 CDS YP_002844961.1 229586460 7815269 294562..295932 1 NC_012633.1 Cytochrome d ubiquinol oxidase subunit I 295932 cydA 7815269 cydA Rickettsia africae ESF-5 Cytochrome d ubiquinol oxidase subunit I YP_002844961.1 294562 D 347255 CDS YP_002844962.1 229586461 7815270 295940..296959 1 NC_012633.1 Cytochrome d ubiquinol oxidase subunit II 296959 cydB 7815270 cydB Rickettsia africae ESF-5 Cytochrome d ubiquinol oxidase subunit II YP_002844962.1 295940 D 347255 CDS YP_002844963.1 229586462 7815271 297161..297403 1 NC_012633.1 Antitoxin of toxin-antitoxin (TA) system StbD 297403 7815271 RAF_ORF0270 Rickettsia africae ESF-5 Antitoxin of toxin-antitoxin (TA) system StbD YP_002844963.1 297161 D 347255 CDS YP_002844964.1 229586463 7815272 297414..297674 1 NC_012633.1 Putative toxin of toxin-antitoxin (TA) system 297674 7815272 RAF_ORF0271 Rickettsia africae ESF-5 Putative toxin of toxin-antitoxin (TA) system YP_002844964.1 297414 D 347255 CDS YP_002844965.1 229586464 7815273 297667..298515 1 NC_012633.1 Beta 1,4 glucosyltransferase 298515 lgtF 7815273 lgtF Rickettsia africae ESF-5 Beta 1,4 glucosyltransferase YP_002844965.1 297667 D 347255 CDS YP_002844966.1 229586465 7815274 298592..299827 1 NC_012633.1 similar to mitochondrial proteases; protease 299827 mpp 7815274 mpp Rickettsia africae ESF-5 protease YP_002844966.1 298592 D 347255 CDS YP_002844967.1 229586466 7815275 299981..300691 1 NC_012633.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 300691 purC 7815275 purC Rickettsia africae ESF-5 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002844967.1 299981 D 347255 CDS YP_002844968.1 229586467 7815276 301101..302498 1 NC_012633.1 hypothetical protein 302498 7815276 RAF_ORF0275 Rickettsia africae ESF-5 hypothetical protein YP_002844968.1 301101 D 347255 CDS YP_002844969.1 229586468 7815277 302594..304501 1 NC_012633.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 304501 thrS 7815277 thrS Rickettsia africae ESF-5 threonyl-tRNA synthetase YP_002844969.1 302594 D 347255 CDS YP_002844970.1 229586469 7815280 complement(307792..308208) 1 NC_012633.1 hypothetical protein 308208 7815280 RAF_ORF0281 Rickettsia africae ESF-5 hypothetical protein YP_002844970.1 307792 R 347255 CDS YP_002844971.1 229586470 7815281 308239..308385 1 NC_012633.1 hypothetical protein 308385 7815281 RAF_ORF0282 Rickettsia africae ESF-5 hypothetical protein YP_002844971.1 308239 D 347255 CDS YP_002844972.1 229586471 7815282 complement(308405..308887) 1 NC_012633.1 hypothetical protein 308887 7815282 RAF_ORF0283 Rickettsia africae ESF-5 hypothetical protein YP_002844972.1 308405 R 347255 CDS YP_002844973.1 229586472 7815283 309597..310958 1 NC_012633.1 Type I secretion outer membrane protein TolC 310958 tolC 7815283 tolC Rickettsia africae ESF-5 Type I secretion outer membrane protein TolC YP_002844973.1 309597 D 347255 CDS YP_002844974.1 229586473 7815284 310960..311358 1 NC_012633.1 hypothetical protein 311358 7815284 RAF_ORF0285 Rickettsia africae ESF-5 hypothetical protein YP_002844974.1 310960 D 347255 CDS YP_002844975.1 229586474 7815285 311575..313296 1 NC_012633.1 Ankyrin repeat protein 313296 7815285 RAF_ORF0286 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002844975.1 311575 D 347255 CDS YP_002844976.1 229586475 7815286 313506..315494 1 NC_012633.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 315494 parE 7815286 parE Rickettsia africae ESF-5 DNA topoisomerase IV subunit B YP_002844976.1 313506 D 347255 CDS YP_002844977.1 229586476 7815287 315610..316980 1 NC_012633.1 Carboxyl-terminal protease 316980 ctp 7815287 ctp Rickettsia africae ESF-5 Carboxyl-terminal protease YP_002844977.1 315610 D 347255 CDS YP_002844978.1 229586477 7815288 317195..318688 1 NC_012633.1 Histidine kinase sensor protein 318688 barA 7815288 barA Rickettsia africae ESF-5 Histidine kinase sensor protein YP_002844978.1 317195 D 347255 CDS YP_002844979.1 229586478 7815289 318754..319491 1 NC_012633.1 hypothetical protein 319491 7815289 RAF_ORF0290 Rickettsia africae ESF-5 hypothetical protein YP_002844979.1 318754 D 347255 CDS YP_002844980.1 229586479 7815290 319504..320166 1 NC_012633.1 hypothetical protein 320166 7815290 RAF_ORF0291 Rickettsia africae ESF-5 hypothetical protein YP_002844980.1 319504 D 347255 CDS YP_002844981.1 229586480 7815291 320189..321433 1 NC_012633.1 WD40-like repeat protein 321433 7815291 RAF_ORF0292 Rickettsia africae ESF-5 WD40-like repeat protein YP_002844981.1 320189 D 347255 CDS YP_002844982.1 229586481 7815292 321526..321993 1 NC_012633.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 321993 rplM 7815292 rplM Rickettsia africae ESF-5 50S ribosomal protein L13 YP_002844982.1 321526 D 347255 CDS YP_002844983.1 229586482 7815293 322000..322479 1 NC_012633.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 322479 rpsI 7815293 rpsI Rickettsia africae ESF-5 30S ribosomal protein S9 YP_002844983.1 322000 D 347255 CDS YP_002844984.1 229586483 7815295 323218..323418 1 NC_012633.1 D-alanyl-D-alanine dipeptidase 323418 7815295 RAF_ORF0295 Rickettsia africae ESF-5 D-alanyl-D-alanine dipeptidase YP_002844984.1 323218 D 347255 CDS YP_002844985.1 229586484 7815296 324026..324319 1 NC_012633.1 hypothetical protein 324319 7815296 RAF_ORF0296 Rickettsia africae ESF-5 hypothetical protein YP_002844985.1 324026 D 347255 CDS YP_002844986.1 229586485 7815297 complement(324713..325198) 1 NC_012633.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 325198 nudH 7815297 nudH Rickettsia africae ESF-5 dinucleoside polyphosphate hydrolase YP_002844986.1 324713 R 347255 CDS YP_002844987.1 229586486 7815298 complement(325223..326575) 1 NC_012633.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD 326575 pleD 7815298 pleD Rickettsia africae ESF-5 response regulator PleD YP_002844987.1 325223 R 347255 CDS YP_002844988.1 229586487 7815299 326651..327217 1 NC_012633.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 327217 efp 7815299 efp Rickettsia africae ESF-5 elongation factor P YP_002844988.1 326651 D 347255 CDS YP_002844989.1 229586488 7815300 327439..328185 1 NC_012633.1 Extragenic suppressor protein suhB 328185 suhB 7815300 suhB Rickettsia africae ESF-5 Extragenic suppressor protein suhB YP_002844989.1 327439 D 347255 CDS YP_002844990.1 229586489 7815301 328257..328580 1 NC_012633.1 hypothetical protein 328580 7815301 RAF_ORF0301 Rickettsia africae ESF-5 hypothetical protein YP_002844990.1 328257 D 347255 CDS YP_002844991.1 229586490 7815302 328614..329309 1 NC_012633.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 329309 psd 7815302 psd Rickettsia africae ESF-5 phosphatidylserine decarboxylase YP_002844991.1 328614 D 347255 CDS YP_002844992.1 229586491 7815303 329572..330336 1 NC_012633.1 CDP-diacylglycerol--serine O-phosphatidyltransferase 330336 pssA 7815303 pssA Rickettsia africae ESF-5 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_002844992.1 329572 D 347255 CDS YP_002844993.1 229586492 7815304 330345..331397 1 NC_012633.1 Multidrug resistance protein A 331397 emrA 7815304 emrA Rickettsia africae ESF-5 Multidrug resistance protein A YP_002844993.1 330345 D 347255 CDS YP_002844994.1 229586493 7815305 complement(332215..332418) 1 NC_012633.1 hypothetical protein 332418 7815305 RAF_ORF0305 Rickettsia africae ESF-5 hypothetical protein YP_002844994.1 332215 R 347255 CDS YP_002844995.1 229586494 7815306 complement(332415..332657) 1 NC_012633.1 BolA-like protein 332657 bolA1 7815306 bolA1 Rickettsia africae ESF-5 BolA-like protein YP_002844995.1 332415 R 347255 CDS YP_002844996.1 229586495 7815307 332712..333938 1 NC_012633.1 EAL domain containing protein 333938 7815307 RAF_ORF0307 Rickettsia africae ESF-5 EAL domain containing protein YP_002844996.1 332712 D 347255 CDS YP_002844997.1 229586496 7815308 334159..335616 1 NC_012633.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 335616 murC 7815308 murC Rickettsia africae ESF-5 UDP-N-acetylmuramate--L-alanine ligase YP_002844997.1 334159 D 347255 CDS YP_002844998.1 229586497 7815309 335712..336635 1 NC_012633.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 336635 murB 7815309 murB Rickettsia africae ESF-5 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002844998.1 335712 D 347255 CDS YP_002844999.1 229586498 7815310 336879..337844 1 NC_012633.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 337844 ddl 7815310 ddl Rickettsia africae ESF-5 D-alanine--D-alanine ligase YP_002844999.1 336879 D 347255 CDS YP_002845000.1 229586499 7815311 337841..338644 1 NC_012633.1 Cell division protein ftsQ 338644 ftsQ 7815311 ftsQ Rickettsia africae ESF-5 Cell division protein ftsQ YP_002845000.1 337841 D 347255 CDS YP_002845001.1 229586500 7815312 338772..340007 1 NC_012633.1 Cell division protein ftsA 340007 ftsA 7815312 ftsA Rickettsia africae ESF-5 Cell division protein ftsA YP_002845001.1 338772 D 347255 CDS YP_002845002.1 229586501 7815313 complement(340150..340626) 1 NC_012633.1 Membrane protein implicated in regulation of membrane protease activity 340626 7815313 RAF_ORF0313 Rickettsia africae ESF-5 Membrane protein implicated in regulation of membrane protease activity YP_002845002.1 340150 R 347255 CDS YP_002845003.1 229586502 7815314 complement(340610..341137) 1 NC_012633.1 cytochrome C 341137 cycM 7815314 cycM Rickettsia africae ESF-5 cytochrome C YP_002845003.1 340610 R 347255 CDS YP_002845004.1 229586503 7815315 341251..342321 1 NC_012633.1 hypothetical protein 342321 7815315 RAF_ORF0315 Rickettsia africae ESF-5 hypothetical protein YP_002845004.1 341251 D 347255 CDS YP_002845005.1 229586504 7815316 complement(342330..343196) 1 NC_012633.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 343196 lpxC 7815316 lpxC Rickettsia africae ESF-5 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002845005.1 342330 R 347255 CDS YP_002845006.1 229586505 7815317 complement(343560..344708) 1 NC_012633.1 hypothetical protein 344708 7815317 RAF_ORF0317 Rickettsia africae ESF-5 hypothetical protein YP_002845006.1 343560 R 347255 CDS YP_002845007.1 229586506 7815318 345136..347208 1 NC_012633.1 Ribonuclease E 347208 rne 7815318 rne Rickettsia africae ESF-5 Ribonuclease E YP_002845007.1 345136 D 347255 CDS YP_002845008.1 229586507 7815319 347454..348467 1 NC_012633.1 Cytochrome c oxidase assembly protein 348467 coxW 7815319 coxW Rickettsia africae ESF-5 Cytochrome c oxidase assembly protein YP_002845008.1 347454 D 347255 CDS YP_002845009.1 229586508 7815320 348480..349391 1 NC_012633.1 Ribosomal large subunit pseudouridine synthase 349391 rluA1 7815320 rluA1 Rickettsia africae ESF-5 Ribosomal large subunit pseudouridine synthase YP_002845009.1 348480 D 347255 CDS YP_002845010.1 229586509 7815321 349546..350727 1 NC_012633.1 Penicillin-binding protein 4 350727 pbpE 7815321 pbpE Rickettsia africae ESF-5 Penicillin-binding protein 4 YP_002845010.1 349546 D 347255 CDS YP_002845011.1 229586510 7815322 350874..351689 1 NC_012633.1 Exodeoxyribonuclease III 351689 xth1 7815322 xth1 Rickettsia africae ESF-5 Exodeoxyribonuclease III YP_002845011.1 350874 D 347255 CDS YP_002845012.1 229586511 7815323 351712..352692 1 NC_012633.1 Pyruvate dehydrogenase e1 component, alpha subunit precursor 352692 pdhA 7815323 pdhA Rickettsia africae ESF-5 Pyruvate dehydrogenase e1 component, alpha subunit precursor YP_002845012.1 351712 D 347255 CDS YP_002845013.1 229586512 7815324 352856..353836 1 NC_012633.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 353836 pdhB 7815324 pdhB Rickettsia africae ESF-5 pyruvate dehydrogenase subunit beta YP_002845013.1 352856 D 347255 CDS YP_002845014.1 229586513 7815325 complement(353974..355803) 1 NC_012633.1 GTP-binding protein TypA 355803 typA 7815325 typA Rickettsia africae ESF-5 GTP-binding protein TypA YP_002845014.1 353974 R 347255 CDS YP_002845015.1 229586514 7815326 356897..357451 1 NC_012633.1 Outer membrane protein 357451 hlpA 7815326 hlpA Rickettsia africae ESF-5 Outer membrane protein YP_002845015.1 356897 D 347255 CDS YP_002845016.1 229586515 7815327 357633..359084 1 NC_012633.1 catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 359084 icd 7815327 icd Rickettsia africae ESF-5 isocitrate dehydrogenase YP_002845016.1 357633 D 347255 CDS YP_002845017.1 229586516 7815328 359199..359519 1 NC_012633.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G 359519 7815328 RAF_ORF0328 Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit G YP_002845017.1 359199 D 347255 CDS YP_002845018.1 229586517 7815329 359583..360656 1 NC_012633.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 360656 mnhB 7815329 mnhB Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit B YP_002845018.1 359583 D 347255 CDS YP_002845019.1 229586518 7815330 360649..361296 1 NC_012633.1 Heme exporter protein B 361296 ccmB 7815330 ccmB Rickettsia africae ESF-5 Heme exporter protein B YP_002845019.1 360649 D 347255 CDS YP_002845020.1 229586519 7815331 361371..361829 1 NC_012633.1 hypothetical protein 361829 7815331 RAF_ORF0331 Rickettsia africae ESF-5 hypothetical protein YP_002845020.1 361371 D 347255 CDS YP_002845021.1 229586520 7815332 361851..362384 1 NC_012633.1 Ubiquinol-cytochrome c reductase, iron-sulfur subunit 362384 petA 7815332 petA Rickettsia africae ESF-5 Ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_002845021.1 361851 D 347255 CDS YP_002845022.1 229586521 7815333 362391..363587 1 NC_012633.1 Cytochrome b 363587 petB 7815333 petB Rickettsia africae ESF-5 Cytochrome b YP_002845022.1 362391 D 347255 CDS YP_002845023.1 229586522 7815334 364078..364833 1 NC_012633.1 Cytochrome c1, heme protein precursor 364833 fbcH 7815334 fbcH Rickettsia africae ESF-5 Cytochrome c1, heme protein precursor YP_002845023.1 364078 D 347255 CDS YP_002845024.1 229586523 7815336 365624..366127 1 NC_012633.1 Small heat shock protein 366127 hspC1 7815336 hspC1 Rickettsia africae ESF-5 Small heat shock protein YP_002845024.1 365624 D 347255 CDS YP_002845025.1 229586524 7815257 complement(368022..369128) 1 NC_012633.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 369128 prfB 7815257 prfB Rickettsia africae ESF-5 peptide chain release factor 2 YP_002845025.1 368022 R 347255 CDS YP_002845026.1 229586525 7815019 369247..371049 1 NC_012633.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 371049 lepA 7815019 lepA Rickettsia africae ESF-5 GTP-binding protein LepA YP_002845026.1 369247 D 347255 CDS YP_002845027.1 229586526 7815021 complement(372002..372142) 1 NC_012633.1 Plasmid maintenance system antidote protein 372142 7815021 RAF_ORF0345 Rickettsia africae ESF-5 Plasmid maintenance system antidote protein YP_002845027.1 372002 R 347255 CDS YP_002845028.1 229586527 7815023 374644..375240 1 NC_012633.1 hypothetical protein 375240 7815023 RAF_ORF0348 Rickettsia africae ESF-5 hypothetical protein YP_002845028.1 374644 D 347255 CDS YP_002845029.1 229586528 7815024 375575..375886 1 NC_012633.1 Guanosine polyphosphate pyrophosphohydrolase/synthetase 375886 spoT1 7815024 spoT1 Rickettsia africae ESF-5 Guanosine polyphosphate pyrophosphohydrolase/synthetase YP_002845029.1 375575 D 347255 CDS YP_002845030.1 229586529 7815025 376200..376532 1 NC_012633.1 hypothetical protein 376532 7815025 RAF_ORF0350 Rickettsia africae ESF-5 hypothetical protein YP_002845030.1 376200 D 347255 CDS YP_002845031.1 229586530 7815026 complement(376937..378037) 1 NC_012633.1 Rod shape-determining protein rodA 378037 rodA 7815026 rodA Rickettsia africae ESF-5 Rod shape-determining protein rodA YP_002845031.1 376937 R 347255 CDS YP_002845032.1 229586531 7815027 complement(378193..380382) 1 NC_012633.1 Protease II 380382 ptrB 7815027 ptrB Rickettsia africae ESF-5 Protease II YP_002845032.1 378193 R 347255 CDS YP_002845033.1 229586532 7815028 complement(380561..382078) 1 NC_012633.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 382078 nuoL3 7815028 nuoL3 Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit D YP_002845033.1 380561 R 347255 CDS YP_002845034.1 229586533 7815029 complement(382476..382763) 1 NC_012633.1 Antitoxin of toxin-antitoxin (TA) system VapB 382763 vapB1 7815029 vapB1 Rickettsia africae ESF-5 Antitoxin of toxin-antitoxin (TA) system VapB YP_002845034.1 382476 R 347255 CDS YP_002845035.1 229586534 7815030 complement(382950..384413) 1 NC_012633.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 384413 nuoL2 7815030 nuoL2 Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit D YP_002845035.1 382950 R 347255 CDS YP_002845036.1 229586535 7815031 complement(384560..385861) 1 NC_012633.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 385861 nuoN2 7815031 nuoN2 Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit D YP_002845036.1 384560 R 347255 CDS YP_002845037.1 229586536 7815032 complement(385858..386193) 1 NC_012633.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 386193 mnhC 7815032 mnhC Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit C YP_002845037.1 385858 R 347255 CDS YP_002845038.1 229586537 7815033 complement(386272..387024) 1 NC_012633.1 VirB9 387024 virB9-1 7815033 virB9-1 Rickettsia africae ESF-5 VirB9 YP_002845038.1 386272 R 347255 CDS YP_002845039.1 229586538 7815034 complement(387026..387724) 1 NC_012633.1 virulence protein 387724 virB8-1 7815034 virB8-1 Rickettsia africae ESF-5 virulence protein YP_002845039.1 387026 R 347255 CDS YP_002845040.1 229586539 7815035 388185..388364 1 NC_012633.1 hypothetical protein 388364 7815035 RAF_ORF0360 Rickettsia africae ESF-5 hypothetical protein YP_002845040.1 388185 D 347255 CDS YP_002845041.1 229586540 7815036 388414..389145 1 NC_012633.1 virulence protein 389145 virB8-2 7815036 virB8-2 Rickettsia africae ESF-5 virulence protein YP_002845041.1 388414 D 347255 CDS YP_002845042.1 229586541 7815037 389132..389605 1 NC_012633.1 VirB9 389605 virB9-2 7815037 virB9-2 Rickettsia africae ESF-5 VirB9 YP_002845042.1 389132 D 347255 CDS YP_002845043.1 229586542 7815038 389789..391237 1 NC_012633.1 VirB10 391237 virB10 7815038 virB10 Rickettsia africae ESF-5 VirB10 YP_002845043.1 389789 D 347255 CDS YP_002845044.1 229586543 7815039 391234..392238 1 NC_012633.1 type IV secretion system ATPase VirB11 392238 virB11 7815039 virB11 Rickettsia africae ESF-5 type IV secretion system ATPase VirB11 YP_002845044.1 391234 D 347255 CDS YP_002845045.1 229586544 7815040 392393..394168 1 NC_012633.1 type IV secretion system protein VirB8 394168 virD4 7815040 virD4 Rickettsia africae ESF-5 type IV secretion system protein VirB8 YP_002845045.1 392393 D 347255 CDS YP_002845046.1 229586545 7815041 394170..395582 1 NC_012633.1 Guanosine pentaphosphate phosphohydrolase 395582 gppA 7815041 gppA Rickettsia africae ESF-5 Guanosine pentaphosphate phosphohydrolase YP_002845046.1 394170 D 347255 CDS YP_002845047.1 229586546 7815042 complement(395796..396197) 1 NC_012633.1 hypothetical protein 396197 7815042 RAF_ORF0367 Rickettsia africae ESF-5 hypothetical protein YP_002845047.1 395796 R 347255 CDS YP_002845048.1 229586547 7815043 complement(396235..396525) 1 NC_012633.1 hypothetical protein 396525 7815043 RAF_ORF0368 Rickettsia africae ESF-5 hypothetical protein YP_002845048.1 396235 R 347255 CDS YP_002845049.1 229586548 7815044 complement(396984..397364) 1 NC_012633.1 hypothetical protein 397364 7815044 RAF_ORF0369 Rickettsia africae ESF-5 hypothetical protein YP_002845049.1 396984 R 347255 CDS YP_002845050.1 229586549 7815045 397587..397871 1 NC_012633.1 Phage portal protein 397871 7815045 RAF_ORF0370 Rickettsia africae ESF-5 Phage portal protein YP_002845050.1 397587 D 347255 CDS YP_002845051.1 229586550 7815046 complement(398147..398272) 1 NC_012633.1 hypothetical protein 398272 7815046 RAF_ORF0371 Rickettsia africae ESF-5 hypothetical protein YP_002845051.1 398147 R 347255 CDS YP_002845052.1 229586551 7815047 398505..399392 1 NC_012633.1 hypothetical protein 399392 7815047 RAF_ORF0372 Rickettsia africae ESF-5 hypothetical protein YP_002845052.1 398505 D 347255 CDS YP_002845053.1 229586552 7815048 399355..400200 1 NC_012633.1 hypothetical protein 400200 7815048 RAF_ORF0373 Rickettsia africae ESF-5 hypothetical protein YP_002845053.1 399355 D 347255 CDS YP_002845054.1 229586553 7815049 400203..400979 1 NC_012633.1 3'(2'),5'-bisphosphate nucleotidase 400979 cysQ 7815049 cysQ Rickettsia africae ESF-5 3'(2'),5'-bisphosphate nucleotidase YP_002845054.1 400203 D 347255 CDS YP_002845055.1 229586554 7815050 complement(401119..403791) 1 NC_012633.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 403791 mutS 7815050 mutS Rickettsia africae ESF-5 DNA mismatch repair protein MutS YP_002845055.1 401119 R 347255 CDS YP_002845056.1 229586555 7815051 complement(403964..404398) 1 NC_012633.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 404398 lacA 7815051 lacA Rickettsia africae ESF-5 ribose-5-phosphate isomerase B YP_002845056.1 403964 R 347255 CDS YP_002845057.1 229586556 7815052 404450..405124 1 NC_012633.1 Membrane-bound metallopeptidase 405124 nlpD1 7815052 nlpD1 Rickettsia africae ESF-5 Membrane-bound metallopeptidase YP_002845057.1 404450 D 347255 CDS YP_002845058.1 229586557 7815053 405125..405817 1 NC_012633.1 Putative metal-dependent hydrolase 405817 7815053 RAF_ORF0378 Rickettsia africae ESF-5 Putative metal-dependent hydrolase YP_002845058.1 405125 D 347255 CDS YP_002845059.1 229586558 7815054 405908..406792 1 NC_012633.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 406792 thyX 7815054 thyX Rickettsia africae ESF-5 FAD-dependent thymidylate synthase YP_002845059.1 405908 D 347255 CDS YP_002845060.1 229586559 7815055 406867..408201 1 NC_012633.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 408201 tolB 7815055 tolB Rickettsia africae ESF-5 translocation protein TolB YP_002845060.1 406867 D 347255 CDS YP_002845061.1 229586560 7815056 complement(408340..409221) 1 NC_012633.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 409221 rpoH 7815056 rpoH Rickettsia africae ESF-5 RNA polymerase factor sigma-32 YP_002845061.1 408340 R 347255 CDS YP_002845062.1 229586561 7815057 409310..409876 1 NC_012633.1 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 409876 cox11 7815057 cox11 Rickettsia africae ESF-5 cytochrome C oxidase assembly protein YP_002845062.1 409310 D 347255 CDS YP_002845063.1 229586562 7815058 complement(409974..410954) 1 NC_012633.1 hypothetical protein 410954 7815058 RAF_ORF0383 Rickettsia africae ESF-5 hypothetical protein YP_002845063.1 409974 R 347255 CDS YP_002845064.1 229586563 7815059 411222..412319 1 NC_012633.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 412319 mnmA 7815059 mnmA Rickettsia africae ESF-5 tRNA-specific 2-thiouridylase MnmA YP_002845064.1 411222 D 347255 CDS YP_002845065.1 229586564 7815060 412450..413847 1 NC_012633.1 Cationic amino acid transporter-1 413847 atrC1 7815060 atrC1 Rickettsia africae ESF-5 Cationic amino acid transporter-1 YP_002845065.1 412450 D 347255 CDS YP_002845066.1 229586565 7815061 413997..415241 1 NC_012633.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 415241 hisS 7815061 hisS Rickettsia africae ESF-5 histidyl-tRNA synthetase YP_002845066.1 413997 D 347255 CDS YP_002845067.1 229586566 7815062 415674..415871 1 NC_012633.1 ABC transporter ATP-binding protein 415871 7815062 RAF_ORF0387 Rickettsia africae ESF-5 ABC transporter ATP-binding protein YP_002845067.1 415674 D 347255 CDS YP_002845068.1 229586567 7815063 415943..416152 1 NC_012633.1 ABC transporter ATP-binding protein 416152 7815063 RAF_ORF0388 Rickettsia africae ESF-5 ABC transporter ATP-binding protein YP_002845068.1 415943 D 347255 CDS YP_002845069.1 229586568 7815064 complement(416552..416956) 1 NC_012633.1 hypothetical protein 416956 7815064 RAF_ORF0389 Rickettsia africae ESF-5 hypothetical protein YP_002845069.1 416552 R 347255 CDS YP_002845070.1 229586569 7815065 complement(417030..418034) 1 NC_012633.1 hypothetical protein 418034 7815065 RAF_ORF0390 Rickettsia africae ESF-5 hypothetical protein YP_002845070.1 417030 R 347255 CDS YP_002845071.1 229586570 7815066 complement(418495..418923) 1 NC_012633.1 hypothetical protein 418923 7815066 RAF_ORF0391 Rickettsia africae ESF-5 hypothetical protein YP_002845071.1 418495 R 347255 CDS YP_002845072.1 229586571 7815067 419425..420150 1 NC_012633.1 TolQ 420150 tolQ 7815067 tolQ Rickettsia africae ESF-5 TolQ YP_002845072.1 419425 D 347255 CDS YP_002845073.1 229586572 7815068 420150..420581 1 NC_012633.1 TolR 420581 tolR 7815068 tolR Rickettsia africae ESF-5 TolR YP_002845073.1 420150 D 347255 CDS YP_002845074.1 229586573 7815069 420571..421542 1 NC_012633.1 Periplasmic protein TonB, links inner and outer membranes 421542 7815069 RAF_ORF0394 Rickettsia africae ESF-5 Periplasmic protein TonB, links inner and outer membranes YP_002845074.1 420571 D 347255 CDS YP_002845075.1 229586574 7815070 422516..423223 1 NC_012633.1 Guanosine polyphosphate pyrophosphohydrolase/synthetase 423223 spoT2 7815070 spoT2 Rickettsia africae ESF-5 Guanosine polyphosphate pyrophosphohydrolase/synthetase YP_002845075.1 422516 D 347255 CDS YP_002845076.1 229586575 7815071 complement(423174..424490) 1 NC_012633.1 Proline/betaine transporter 424490 proP2 7815071 proP2 Rickettsia africae ESF-5 Proline/betaine transporter YP_002845076.1 423174 R 347255 CDS YP_002845077.1 229586576 7815072 complement(424629..426164) 1 NC_012633.1 HlyD family secretion protein 426164 7815072 RAF_ORF0397 Rickettsia africae ESF-5 HlyD family secretion protein YP_002845077.1 424629 R 347255 CDS YP_002845078.1 229586577 7815073 complement(426349..428103) 1 NC_012633.1 Alkaline protease secretion ATP-binding protein AprD 428103 aprD 7815073 aprD Rickettsia africae ESF-5 Alkaline protease secretion ATP-binding protein AprD YP_002845078.1 426349 R 347255 CDS YP_002845079.1 229586578 7815074 complement(428114..429130) 1 NC_012633.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 429130 asd 7815074 asd Rickettsia africae ESF-5 aspartate-semialdehyde dehydrogenase YP_002845079.1 428114 R 347255 CDS YP_002845080.1 229586579 7815075 complement(429123..429485) 1 NC_012633.1 Protein kinase C inhibitor 1 429485 pkcI 7815075 pkcI Rickettsia africae ESF-5 Protein kinase C inhibitor 1 YP_002845080.1 429123 R 347255 CDS YP_002845081.1 229586580 7815076 complement(429673..430026) 1 NC_012633.1 hypothetical protein 430026 7815076 RAF_ORF0401 Rickettsia africae ESF-5 hypothetical protein YP_002845081.1 429673 R 347255 CDS YP_002845082.1 229586581 7815077 430290..430838 1 NC_012633.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 430838 hslV 7815077 hslV Rickettsia africae ESF-5 ATP-dependent protease peptidase subunit YP_002845082.1 430290 D 347255 CDS YP_002845083.1 229586582 7815078 430835..432187 1 NC_012633.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 432187 hslU 7815078 hslU Rickettsia africae ESF-5 ATP-dependent protease ATP-binding subunit HslU YP_002845083.1 430835 D 347255 CDS YP_002845084.1 229586583 7815080 434337..434915 1 NC_012633.1 hypothetical protein 434915 7815080 RAF_ORF0407 Rickettsia africae ESF-5 hypothetical protein YP_002845084.1 434337 D 347255 CDS YP_002845085.1 229586584 7815081 434925..436265 1 NC_012633.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 436265 lpxB 7815081 lpxB Rickettsia africae ESF-5 lipid-A-disaccharide synthase YP_002845085.1 434925 D 347255 CDS YP_002845086.1 229586585 7815082 complement(436262..436534) 1 NC_012633.1 hypothetical protein 436534 7815082 RAF_ORF0409 Rickettsia africae ESF-5 hypothetical protein YP_002845086.1 436262 R 347255 CDS YP_002845087.1 229586586 7815083 436881..437900 1 NC_012633.1 Aminodeoxychorismate lyase 437900 7815083 RAF_ORF0410 Rickettsia africae ESF-5 Aminodeoxychorismate lyase YP_002845087.1 436881 D 347255 CDS YP_002845088.1 229586587 7815084 438040..438351 1 NC_012633.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 438351 cyaY 7815084 cyaY Rickettsia africae ESF-5 frataxin-like protein YP_002845088.1 438040 D 347255 CDS YP_002845089.1 229586588 7815085 438489..439058 1 NC_012633.1 hypothetical protein 439058 7815085 RAF_ORF0412 Rickettsia africae ESF-5 hypothetical protein YP_002845089.1 438489 D 347255 CDS YP_002845090.1 229586589 7815086 439826..439960 1 NC_012633.1 hypothetical protein 439960 7815086 RAF_ORF0413 Rickettsia africae ESF-5 hypothetical protein YP_002845090.1 439826 D 347255 CDS YP_002845091.1 229586590 7815087 440123..440674 1 NC_012633.1 hypothetical protein 440674 7815087 RAF_ORF0414 Rickettsia africae ESF-5 hypothetical protein YP_002845091.1 440123 D 347255 CDS YP_002845092.1 229586591 7815088 441169..441453 1 NC_012633.1 hypothetical protein 441453 7815088 RAF_ORF0415 Rickettsia africae ESF-5 hypothetical protein YP_002845092.1 441169 D 347255 CDS YP_002845093.1 229586592 7815089 complement(441811..443154) 1 NC_012633.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 443154 gltX 7815089 gltX Rickettsia africae ESF-5 glutamyl-tRNA synthetase YP_002845093.1 441811 R 347255 CDS YP_002845094.1 229586593 7815090 complement(443263..445593) 1 NC_012633.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 445593 topA 7815090 topA Rickettsia africae ESF-5 DNA topoisomerase I YP_002845094.1 443263 R 347255 CDS YP_002845095.1 229586594 7815092 complement(446994..447602) 1 NC_012633.1 Thioredoxin peroxidase 1 447602 tdpX1 7815092 tdpX1 Rickettsia africae ESF-5 Thioredoxin peroxidase 1 YP_002845095.1 446994 R 347255 CDS YP_002845096.1 229586595 7815093 complement(447678..448616) 1 NC_012633.1 Membrane protease subunit, stomatin/prohibitin-like protein 448616 hflC1 7815093 hflC1 Rickettsia africae ESF-5 Membrane protease subunit, stomatin/prohibitin-like protein YP_002845096.1 447678 R 347255 CDS YP_002845097.1 229586596 7815094 complement(448981..450549) 1 NC_012633.1 Putative membrane-associated metal-dependent hydrolase 450549 7815094 RAF_ORF0422 Rickettsia africae ESF-5 Putative membrane-associated metal-dependent hydrolase YP_002845097.1 448981 R 347255 CDS YP_002845098.1 229586597 7815095 450585..451049 1 NC_012633.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 451049 7815095 RAF_ORF0423 Rickettsia africae ESF-5 Holliday junction resolvase-like protein YP_002845098.1 450585 D 347255 CDS YP_002845099.1 229586598 7815096 451307..451477 1 NC_012633.1 Plasmid maintenance system antidote protein 451477 7815096 RAF_ORF0424 Rickettsia africae ESF-5 Plasmid maintenance system antidote protein YP_002845099.1 451307 D 347255 CDS YP_002845100.1 229586599 7815097 451648..452502 1 NC_012633.1 dTDP-4-dehydrorhamnose reductase 452502 7815097 RAF_ORF0425 Rickettsia africae ESF-5 dTDP-4-dehydrorhamnose reductase YP_002845100.1 451648 D 347255 CDS YP_002845101.1 229586600 7815098 452685..453710 1 NC_012633.1 Putative nucleoside-diphosphate sugar epimerase CapD 453710 capD 7815098 capD Rickettsia africae ESF-5 Putative nucleoside-diphosphate sugar epimerase CapD YP_002845101.1 452685 D 347255 CDS YP_002845102.1 229586601 7815018 453703..454836 1 NC_012633.1 UDP-N-acetylglucosamine 2-epimerase 454836 rffE 7815018 rffE Rickettsia africae ESF-5 UDP-N-acetylglucosamine 2-epimerase YP_002845102.1 453703 D 347255 CDS YP_002845103.1 229586602 7815498 454796..456142 1 NC_012633.1 hypothetical protein 456142 7815498 RAF_ORF0428 Rickettsia africae ESF-5 hypothetical protein YP_002845103.1 454796 D 347255 CDS YP_002845104.1 229586603 7815499 456158..456406 1 NC_012633.1 hypothetical protein 456406 7815499 RAF_ORF0429 Rickettsia africae ESF-5 hypothetical protein YP_002845104.1 456158 D 347255 CDS YP_002845105.1 229586604 7815500 457080..458894 1 NC_012633.1 Glycosyltransferase, two domains 458894 7815500 RAF_ORF0430 Rickettsia africae ESF-5 Glycosyltransferase, two domains YP_002845105.1 457080 D 347255 CDS YP_002845106.1 229586605 7815501 complement(458899..459897) 1 NC_012633.1 Efflux transporter, RND family, MFP subunit 459897 7815501 RAF_ORF0431 Rickettsia africae ESF-5 Efflux transporter, RND family, MFP subunit YP_002845106.1 458899 R 347255 CDS YP_002845107.1 229586606 7815502 complement(459984..460778) 1 NC_012633.1 hypothetical protein 460778 7815502 RAF_ORF0432 Rickettsia africae ESF-5 hypothetical protein YP_002845107.1 459984 R 347255 CDS YP_002845108.1 229586607 7815503 complement(460788..461555) 1 NC_012633.1 Putative hydrolase/acyltransferase 461555 7815503 RAF_ORF0433 Rickettsia africae ESF-5 Putative hydrolase/acyltransferase YP_002845108.1 460788 R 347255 CDS YP_002845109.1 229586608 7815504 461588..462760 1 NC_012633.1 Glycosyltransferase 462760 7815504 RAF_ORF0434 Rickettsia africae ESF-5 Glycosyltransferase YP_002845109.1 461588 D 347255 CDS YP_002845110.1 229586609 7815505 complement(465262..465879) 1 NC_012633.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 465879 rpsD 7815505 rpsD Rickettsia africae ESF-5 30S ribosomal protein S4 YP_002845110.1 465262 R 347255 CDS YP_002845111.1 229586610 7815506 466004..466921 1 NC_012633.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 466921 cyoB 7815506 cyoB Rickettsia africae ESF-5 protoheme IX farnesyltransferase YP_002845111.1 466004 D 347255 CDS YP_002845112.1 229586611 7815507 complement(467327..467956) 1 NC_012633.1 Putative lyase 467956 7815507 RAF_ORF0437 Rickettsia africae ESF-5 Putative lyase YP_002845112.1 467327 R 347255 CDS YP_002845113.1 229586612 7815508 468436..468795 1 NC_012633.1 hypothetical protein 468795 7815508 RAF_ORF0438 Rickettsia africae ESF-5 hypothetical protein YP_002845113.1 468436 D 347255 CDS YP_002845114.1 229586613 7815509 complement(468936..471455) 1 NC_012633.1 Outer membrane assembly protein 471455 asmA 7815509 asmA Rickettsia africae ESF-5 Outer membrane assembly protein YP_002845114.1 468936 R 347255 CDS YP_002845115.1 229586614 7815510 complement(471738..472235) 1 NC_012633.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 472235 rimM 7815510 rimM Rickettsia africae ESF-5 16S rRNA-processing protein RimM YP_002845115.1 471738 R 347255 CDS YP_002845116.1 229586615 7815511 472298..474928 1 NC_012633.1 hypothetical protein 474928 7815511 RAF_ORF0441 Rickettsia africae ESF-5 hypothetical protein YP_002845116.1 472298 D 347255 CDS YP_002845117.1 229586616 7815512 474942..475184 1 NC_012633.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 475184 xseB 7815512 xseB Rickettsia africae ESF-5 exodeoxyribonuclease VII small subunit YP_002845117.1 474942 D 347255 CDS YP_002845118.1 229586617 7815514 475880..476605 1 NC_012633.1 hypothetical protein 476605 7815514 RAF_ORF0445 Rickettsia africae ESF-5 hypothetical protein YP_002845118.1 475880 D 347255 CDS YP_002845119.1 229586618 7815515 complement(476571..477122) 1 NC_012633.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 477122 mpg 7815515 mpg Rickettsia africae ESF-5 3-methyladenine DNA glycosylase YP_002845119.1 476571 R 347255 CDS YP_002845120.1 229586619 7815516 complement(477416..477664) 1 NC_012633.1 hypothetical protein 477664 7815516 RAF_ORF0447 Rickettsia africae ESF-5 hypothetical protein YP_002845120.1 477416 R 347255 CDS YP_002845121.1 229586620 7815517 complement(477657..478160) 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 478160 nuoE 7815517 nuoE Rickettsia africae ESF-5 NADH dehydrogenase subunit E YP_002845121.1 477657 R 347255 CDS YP_002845122.1 229586621 7815518 complement(478586..479854) 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 479854 nuoD 7815518 nuoD Rickettsia africae ESF-5 NADH dehydrogenase subunit D YP_002845122.1 478586 R 347255 CDS YP_002845123.1 229586622 7815519 complement(479860..480588) 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 480588 nuoC 7815519 nuoC Rickettsia africae ESF-5 NADH dehydrogenase subunit C YP_002845123.1 479860 R 347255 CDS YP_002845124.1 229586623 7815520 complement(480566..481090) 1 NC_012633.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 481090 nuoB 7815520 nuoB Rickettsia africae ESF-5 NADH dehydrogenase subunit B YP_002845124.1 480566 R 347255 CDS YP_002845125.1 229586624 7815521 complement(481095..481493) 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 481493 nuoA 7815521 nuoA Rickettsia africae ESF-5 NADH dehydrogenase subunit A YP_002845125.1 481095 R 347255 CDS YP_002845126.1 229586625 7815522 complement(481624..482859) 1 NC_012633.1 Putative lipid A core - O-antigen ligase 482859 rfaL 7815522 rfaL Rickettsia africae ESF-5 Putative lipid A core - O-antigen ligase YP_002845126.1 481624 R 347255 CDS YP_002845127.1 229586626 7815523 complement(482860..483333) 1 NC_012633.1 hypothetical protein 483333 7815523 RAF_ORF0454 Rickettsia africae ESF-5 hypothetical protein YP_002845127.1 482860 R 347255 CDS YP_002845128.1 229586627 7815526 485147..486067 1 NC_012633.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 486067 xerD 7815526 xerD Rickettsia africae ESF-5 site-specific tyrosine recombinase XerD YP_002845128.1 485147 D 347255 CDS YP_002845129.1 229586628 7815527 486151..487170 1 NC_012633.1 hypothetical protein 487170 7815527 RAF_ORF0460 Rickettsia africae ESF-5 hypothetical protein YP_002845129.1 486151 D 347255 CDS YP_002845130.1 229586629 7815528 487264..488445 1 NC_012633.1 hypothetical protein 488445 7815528 RAF_ORF0461 Rickettsia africae ESF-5 hypothetical protein YP_002845130.1 487264 D 347255 CDS YP_002845131.1 229586630 7815529 complement(488632..489372) 1 NC_012633.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 489372 fabI 7815529 fabI Rickettsia africae ESF-5 enoyl-(acyl carrier protein) reductase YP_002845131.1 488632 R 347255 CDS YP_002845132.1 229586631 7815530 489494..491008 1 NC_012633.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 491008 lnt 7815530 lnt Rickettsia africae ESF-5 apolipoprotein N-acyltransferase YP_002845132.1 489494 D 347255 CDS YP_002845133.1 229586632 7815531 491698..492501 1 NC_012633.1 Negative regulator of beta-lactamase expression 492501 ampD1 7815531 ampD1 Rickettsia africae ESF-5 Negative regulator of beta-lactamase expression YP_002845133.1 491698 D 347255 CDS YP_002845134.1 229586633 7815532 492953..493870 1 NC_012633.1 ABC transporter substrate-binding protein 493870 7815532 RAF_ORF0465 Rickettsia africae ESF-5 ABC transporter substrate-binding protein YP_002845134.1 492953 D 347255 CDS YP_002845135.1 229586634 7815533 493797..494714 1 NC_012633.1 ABC transporter permease 494714 7815533 RAF_ORF0466 Rickettsia africae ESF-5 ABC transporter permease YP_002845135.1 493797 D 347255 CDS YP_002845136.1 229586635 7815534 494711..495433 1 NC_012633.1 ABC transporter ATP-binding protein 495433 7815534 RAF_ORF0467 Rickettsia africae ESF-5 ABC transporter ATP-binding protein YP_002845136.1 494711 D 347255 CDS YP_002845137.1 229586636 7815535 complement(495513..495896) 1 NC_012633.1 hypothetical protein 495896 7815535 RAF_ORF0468 Rickettsia africae ESF-5 hypothetical protein YP_002845137.1 495513 R 347255 CDS YP_002845138.1 229586637 7815537 complement(497244..497762) 1 NC_012633.1 Disulfide bond formation protein DsbB 497762 dsbB 7815537 dsbB Rickettsia africae ESF-5 Disulfide bond formation protein DsbB YP_002845138.1 497244 R 347255 CDS YP_002845139.1 229586638 7815538 497941..499509 1 NC_012633.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 499509 lysK 7815538 lysK Rickettsia africae ESF-5 lysyl-tRNA synthetase YP_002845139.1 497941 D 347255 CDS YP_002845140.1 229586639 7815539 499643..500575 1 NC_012633.1 Putative permease 500575 7815539 RAF_ORF0473 Rickettsia africae ESF-5 Putative permease YP_002845140.1 499643 D 347255 CDS YP_002845141.1 229586640 7815540 500715..503018 1 NC_012633.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 503018 tme 7815540 tme Rickettsia africae ESF-5 malic enzyme YP_002845141.1 500715 D 347255 CDS YP_002845142.1 229586641 7815541 complement(504128..504541) 1 NC_012633.1 hypothetical protein 504541 7815541 RAF_ORF0475 Rickettsia africae ESF-5 hypothetical protein YP_002845142.1 504128 R 347255 CDS YP_002845143.1 229586642 7815542 complement(504507..504755) 1 NC_012633.1 Transcriptional regulator, AbrB family 504755 7815542 RAF_ORF0476 Rickettsia africae ESF-5 Transcriptional regulator, AbrB family YP_002845143.1 504507 R 347255 CDS YP_002845144.1 229586643 7815543 504992..506209 1 NC_012633.1 Proline/betaine transporter 506209 proP3 7815543 proP3 Rickettsia africae ESF-5 Proline/betaine transporter YP_002845144.1 504992 D 347255 CDS YP_002845145.1 229586644 7815545 complement(509630..510574) 1 NC_012633.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 510574 mdh 7815545 mdh Rickettsia africae ESF-5 malate dehydrogenase YP_002845145.1 509630 R 347255 CDS YP_002845146.1 229586645 7815546 510690..510941 1 NC_012633.1 Ankyrin repeat protein 510941 7815546 RAF_ORF0482 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002845146.1 510690 D 347255 CDS YP_002845147.1 229586646 7815547 complement(512072..513595) 1 NC_012633.1 ATP/ADP translocase 513595 tlc2 7815547 tlc2 Rickettsia africae ESF-5 ATP/ADP translocase YP_002845147.1 512072 R 347255 CDS YP_002845148.1 229586647 7815548 complement(513804..515417) 1 NC_012633.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 515417 pyrG 7815548 pyrG Rickettsia africae ESF-5 CTP synthetase YP_002845148.1 513804 R 347255 CDS YP_002845149.1 229586648 7815549 complement(515420..516160) 1 NC_012633.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 516160 kdsB 7815549 kdsB Rickettsia africae ESF-5 3-deoxy-manno-octulosonate cytidylyltransferase YP_002845149.1 515420 R 347255 CDS YP_002845150.1 229586649 7815552 516711..516839 1 NC_012633.1 hypothetical protein 516839 7815552 RAF_ORF0486 Rickettsia africae ESF-5 hypothetical protein YP_002845150.1 516711 D 347255 CDS YP_002845151.1 229586650 7815553 complement(516932..517222) 1 NC_012633.1 ADP-ribose pyrophosphatase MutT 517222 mutT 7815553 mutT Rickettsia africae ESF-5 ADP-ribose pyrophosphatase MutT YP_002845151.1 516932 R 347255 CDS YP_002845152.1 229586651 7815554 517389..518912 1 NC_012633.1 hypothetical protein 518912 7815554 RAF_ORF0488 Rickettsia africae ESF-5 hypothetical protein YP_002845152.1 517389 D 347255 CDS YP_002845153.1 229586652 7815555 518905..519474 1 NC_012633.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 519474 folE 7815555 folE Rickettsia africae ESF-5 GTP cyclohydrolase I YP_002845153.1 518905 D 347255 CDS YP_002845154.1 229586653 7815556 519639..520919 1 NC_012633.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 520919 proS 7815556 proS Rickettsia africae ESF-5 prolyl-tRNA synthetase YP_002845154.1 519639 D 347255 CDS YP_002845155.1 229586654 7815557 521132..522100 1 NC_012633.1 Cell filamentation protein Fic 522100 7815557 RAF_ORF0491 Rickettsia africae ESF-5 Cell filamentation protein Fic YP_002845155.1 521132 D 347255 CDS YP_002845156.1 229586655 7815558 522291..522497 1 NC_012633.1 hypothetical protein 522497 7815558 RAF_ORF0492 Rickettsia africae ESF-5 hypothetical protein YP_002845156.1 522291 D 347255 CDS YP_002845157.1 229586656 7815559 522502..523113 1 NC_012633.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 523113 ruvA 7815559 ruvA Rickettsia africae ESF-5 Holliday junction DNA helicase RuvA YP_002845157.1 522502 D 347255 CDS YP_002845158.1 229586657 7815560 523748..524035 1 NC_012633.1 hypothetical protein 524035 7815560 RAF_ORF0494 Rickettsia africae ESF-5 hypothetical protein YP_002845158.1 523748 D 347255 CDS YP_002845159.1 229586658 7815561 524111..525139 1 NC_012633.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 525139 ruvB 7815561 ruvB Rickettsia africae ESF-5 Holliday junction DNA helicase RuvB YP_002845159.1 524111 D 347255 CDS YP_002845160.1 229586659 7815562 525132..526895 1 NC_012633.1 Multidrug resistance protein 526895 msbA1 7815562 msbA1 Rickettsia africae ESF-5 Multidrug resistance protein YP_002845160.1 525132 D 347255 CDS YP_002845161.1 229586660 7815563 527089..528333 1 NC_012633.1 AmpG protein 528333 ampG4 7815563 ampG4 Rickettsia africae ESF-5 AmpG protein YP_002845161.1 527089 D 347255 CDS YP_002845162.1 229586661 7815564 528510..529430 1 NC_012633.1 Penicillin-binding protein dacF precursor 529430 dacF 7815564 dacF Rickettsia africae ESF-5 Penicillin-binding protein dacF precursor YP_002845162.1 528510 D 347255 CDS YP_002845163.1 229586662 7815565 complement(529600..530562) 1 NC_012633.1 Rare lipoprotein A precursor 530562 rlpA 7815565 rlpA Rickettsia africae ESF-5 Rare lipoprotein A precursor YP_002845163.1 529600 R 347255 CDS YP_002845164.1 229586663 7815566 complement(530540..531157) 1 NC_012633.1 Putative periplasmic or secreted lipoprotein 531157 osmY 7815566 osmY Rickettsia africae ESF-5 Putative periplasmic or secreted lipoprotein YP_002845164.1 530540 R 347255 CDS YP_002845165.1 229586664 7815567 complement(531390..531932) 1 NC_012633.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 531932 ispZ 7815567 ispZ Rickettsia africae ESF-5 intracellular septation protein A YP_002845165.1 531390 R 347255 CDS YP_002845166.1 229586665 7815568 complement(531962..532810) 1 NC_012633.1 FTR1 family protein 532810 7815568 RAF_ORF0502 Rickettsia africae ESF-5 FTR1 family protein YP_002845166.1 531962 R 347255 CDS YP_002845167.1 229586666 7815569 complement(532820..533200) 1 NC_012633.1 hypothetical protein 533200 7815569 RAF_ORF0503 Rickettsia africae ESF-5 hypothetical protein YP_002845167.1 532820 R 347255 CDS YP_002845168.1 229586667 7815570 complement(533391..534386) 1 NC_012633.1 hypothetical protein 534386 7815570 RAF_ORF0504 Rickettsia africae ESF-5 hypothetical protein YP_002845168.1 533391 R 347255 CDS YP_002845169.1 229586668 7815571 534531..535157 1 NC_012633.1 Protocatechuate-3,4-dioxygenase, beta subunit 535157 7815571 RAF_ORF0505 Rickettsia africae ESF-5 Protocatechuate-3,4-dioxygenase, beta subunit YP_002845169.1 534531 D 347255 CDS YP_002845170.1 229586669 7815572 535365..536009 1 NC_012633.1 Thiol:disulfide interchange protein tlpA 536009 tlpA 7815572 tlpA Rickettsia africae ESF-5 Thiol:disulfide interchange protein tlpA YP_002845170.1 535365 D 347255 CDS YP_002845171.1 229586670 7815573 536174..537088 1 NC_012633.1 signal peptide peptidase SppA 537088 sppA1 7815573 sppA1 Rickettsia africae ESF-5 signal peptide peptidase SppA YP_002845171.1 536174 D 347255 CDS YP_002845172.1 229586671 7815574 537090..537536 1 NC_012633.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 537536 dut 7815574 dut Rickettsia africae ESF-5 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002845172.1 537090 D 347255 CDS YP_002845173.1 229586672 7815575 537754..539715 1 NC_012633.1 lytic murein transglycosylase 539715 mltE1 7815575 mltE1 Rickettsia africae ESF-5 lytic murein transglycosylase YP_002845173.1 537754 D 347255 CDS YP_002845174.1 229586673 7815576 539802..540761 1 NC_012633.1 hypothetical protein 540761 7815576 RAF_ORF0510 Rickettsia africae ESF-5 hypothetical protein YP_002845174.1 539802 D 347255 CDS YP_002845175.1 229586674 7815577 540955..541902 1 NC_012633.1 Microcin C7 self-immunity protein 541902 mccF 7815577 mccF Rickettsia africae ESF-5 Microcin C7 self-immunity protein YP_002845175.1 540955 D 347255 CDS YP_002845176.1 229586675 7816011 complement(542081..544597) 1 NC_012633.1 recombinase B 544597 7816011 RAF_ORF0512 Rickettsia africae ESF-5 recombinase B YP_002845176.1 542081 R 347255 CDS YP_002845177.1 229586676 7814937 544748..545149 1 NC_012633.1 hypothetical protein 545149 7814937 RAF_ORF0513 Rickettsia africae ESF-5 hypothetical protein YP_002845177.1 544748 D 347255 CDS YP_002845178.1 229586677 7814938 complement(545153..545881) 1 NC_012633.1 Putative glutamine amidotransferase 545881 7814938 RAF_ORF0514 Rickettsia africae ESF-5 Putative glutamine amidotransferase YP_002845178.1 545153 R 347255 CDS YP_002845179.1 229586678 7814939 complement(546079..547677) 1 NC_012633.1 cytochrome c oxidase polypeptide I 547677 coxA 7814939 coxA Rickettsia africae ESF-5 cytochrome c oxidase polypeptide I YP_002845179.1 546079 R 347255 CDS YP_002845180.1 229586679 7814940 complement(547683..548066) 1 NC_012633.1 Acetyltransferase 548066 7814940 RAF_ORF0516 Rickettsia africae ESF-5 Acetyltransferase YP_002845180.1 547683 R 347255 CDS YP_002845181.1 229586680 7814941 complement(548259..549206) 1 NC_012633.1 cytochrome c oxidase polypeptide II 549206 coxB 7814941 coxB Rickettsia africae ESF-5 cytochrome c oxidase polypeptide II YP_002845181.1 548259 R 347255 CDS YP_002845182.1 229586681 7814942 complement(549390..549809) 1 NC_012633.1 Glycerol-3-phosphate cytidyltransferase TagD 549809 tagD 7814942 tagD Rickettsia africae ESF-5 Glycerol-3-phosphate cytidyltransferase TagD YP_002845182.1 549390 R 347255 CDS YP_002845183.1 229586682 7814943 550048..551412 1 NC_012633.1 Membrane-bound metallopeptidase 551412 nlpD2 7814943 nlpD2 Rickettsia africae ESF-5 Membrane-bound metallopeptidase YP_002845183.1 550048 D 347255 CDS YP_002845184.1 229586683 7814944 551606..552211 1 NC_012633.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 552211 lspA 7814944 lspA Rickettsia africae ESF-5 lipoprotein signal peptidase YP_002845184.1 551606 D 347255 CDS YP_002845185.1 229586684 7814945 552364..552612 1 NC_012633.1 hypothetical protein 552612 7814945 RAF_ORF0521 Rickettsia africae ESF-5 hypothetical protein YP_002845185.1 552364 D 347255 CDS YP_002845186.1 229586685 7814946 552783..554285 1 NC_012633.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 554285 murD 7814946 murD Rickettsia africae ESF-5 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002845186.1 552783 D 347255 CDS YP_002845187.1 229586686 7814947 554417..555550 1 NC_012633.1 Cell division protein ftsW 555550 ftsW 7814947 ftsW Rickettsia africae ESF-5 Cell division protein ftsW YP_002845187.1 554417 D 347255 CDS YP_002845188.1 229586687 7814948 555547..556677 1 NC_012633.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 556677 murG 7814948 murG Rickettsia africae ESF-5 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002845188.1 555547 D 347255 CDS YP_002845189.1 229586688 7814949 557073..557723 1 NC_012633.1 hypothetical protein 557723 7814949 RAF_ORF0525 Rickettsia africae ESF-5 hypothetical protein YP_002845189.1 557073 D 347255 CDS YP_002845190.1 229586689 7814953 complement(564356..565372) 1 NC_012633.1 Glycosyltransferase 565372 7814953 RAF_ORF0536 Rickettsia africae ESF-5 Glycosyltransferase YP_002845190.1 564356 R 347255 CDS YP_002845191.1 229586690 7814954 complement(565372..565656) 1 NC_012633.1 hypothetical protein 565656 7814954 RAF_ORF0537 Rickettsia africae ESF-5 hypothetical protein YP_002845191.1 565372 R 347255 CDS YP_002845192.1 229586691 7814955 complement(565696..565929) 1 NC_012633.1 hypothetical protein 565929 7814955 RAF_ORF0538 Rickettsia africae ESF-5 hypothetical protein YP_002845192.1 565696 R 347255 CDS YP_002845193.1 229586692 7814956 complement(566062..566256) 1 NC_012633.1 hypothetical protein 566256 7814956 RAF_ORF0539 Rickettsia africae ESF-5 hypothetical protein YP_002845193.1 566062 R 347255 CDS YP_002845194.1 229586693 7814957 566345..567157 1 NC_012633.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 567157 dapF 7814957 dapF Rickettsia africae ESF-5 diaminopimelate epimerase YP_002845194.1 566345 D 347255 CDS YP_002845195.1 229586694 7814958 567132..568397 1 NC_012633.1 MiaB-like tRNA modifying enzyme 568397 7814958 RAF_ORF0541 Rickettsia africae ESF-5 MiaB-like tRNA modifying enzyme YP_002845195.1 567132 D 347255 CDS YP_002845196.1 229586695 7814959 568638..569687 1 NC_012633.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 569687 pheS 7814959 pheS Rickettsia africae ESF-5 phenylalanyl-tRNA synthetase subunit alpha YP_002845196.1 568638 D 347255 CDS YP_002845197.1 229586696 7814960 569684..572140 1 NC_012633.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 572140 pheT 7814960 pheT Rickettsia africae ESF-5 phenylalanyl-tRNA synthetase subunit beta YP_002845197.1 569684 D 347255 CDS YP_002845198.1 229586697 7814961 572145..573284 1 NC_012633.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 573284 dnaN 7814961 dnaN Rickettsia africae ESF-5 DNA polymerase III subunit beta YP_002845198.1 572145 D 347255 CDS YP_002845199.1 229586698 7814962 573645..574148 1 NC_012633.1 hypothetical protein 574148 7814962 RAF_ORF0545 Rickettsia africae ESF-5 hypothetical protein YP_002845199.1 573645 D 347255 CDS YP_002845200.1 229586699 7814963 574277..576784 1 NC_012633.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 576784 leuS 7814963 leuS Rickettsia africae ESF-5 leucyl-tRNA synthetase YP_002845200.1 574277 D 347255 CDS YP_002845201.1 229586700 7814964 complement(577835..578446) 1 NC_012633.1 Ribonuclease D 578446 rnd2 7814964 rnd2 Rickettsia africae ESF-5 Ribonuclease D YP_002845201.1 577835 R 347255 CDS YP_002845202.1 229586701 7814965 complement(578597..578902) 1 NC_012633.1 septum formation initiator 578902 7814965 RAF_ORF0548 Rickettsia africae ESF-5 septum formation initiator YP_002845202.1 578597 R 347255 CDS YP_002845203.1 229586702 7814966 complement(578899..579591) 1 NC_012633.1 phosphatidate cytidylyltransferase 579591 cdsA 7814966 cdsA Rickettsia africae ESF-5 phosphatidate cytidylyltransferase YP_002845203.1 578899 R 347255 CDS YP_002845204.1 229586703 7814967 complement(579551..580258) 1 NC_012633.1 UDP pyrophosphate synthetase 580258 uppS 7814967 uppS Rickettsia africae ESF-5 UDP pyrophosphate synthetase YP_002845204.1 579551 R 347255 CDS YP_002845205.1 229586704 7814968 complement(580404..581843) 1 NC_012633.1 Osmolarity sensor protein EnvZ 581843 envZ 7814968 envZ Rickettsia africae ESF-5 Osmolarity sensor protein EnvZ YP_002845205.1 580404 R 347255 CDS YP_002845206.1 229586705 7814969 complement(581818..582498) 1 NC_012633.1 PetR 582498 ompR 7814969 ompR Rickettsia africae ESF-5 PetR YP_002845206.1 581818 R 347255 CDS YP_002845207.1 229586706 7814970 582714..583586 1 NC_012633.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 583586 ilvE 7814970 ilvE Rickettsia africae ESF-5 branched-chain amino acid aminotransferase YP_002845207.1 582714 D 347255 CDS YP_002845208.1 229586707 7814971 583772..584656 1 NC_012633.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 584656 dapA 7814971 dapA Rickettsia africae ESF-5 dihydrodipicolinate synthase YP_002845208.1 583772 D 347255 CDS YP_002845209.1 229586708 7814972 584653..585111 1 NC_012633.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 585111 smpB 7814972 smpB Rickettsia africae ESF-5 SsrA-binding protein YP_002845209.1 584653 D 347255 CDS YP_002845210.1 229586709 7814973 585244..586035 1 NC_012633.1 Thiol:disulfide interchange protein dsbA 586035 dsbA 7814973 dsbA Rickettsia africae ESF-5 Thiol:disulfide interchange protein dsbA YP_002845210.1 585244 D 347255 CDS YP_002845211.1 229586710 7814974 complement(586269..587144) 1 NC_012633.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 587144 sucD 7814974 sucD Rickettsia africae ESF-5 succinyl-CoA synthetase subunit alpha YP_002845211.1 586269 R 347255 CDS YP_002845212.1 229586711 7814975 complement(587320..588480) 1 NC_012633.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 588480 sucC 7814975 sucC Rickettsia africae ESF-5 succinyl-CoA synthetase subunit beta YP_002845212.1 587320 R 347255 CDS YP_002845213.1 229586712 7814976 complement(588513..588932) 1 NC_012633.1 Putative nucleic-acid-binding protein, containing PIN domain 588932 7814976 RAF_ORF0559 Rickettsia africae ESF-5 Putative nucleic-acid-binding protein, containing PIN domain YP_002845213.1 588513 R 347255 CDS YP_002845214.1 229586713 7814977 complement(588889..589140) 1 NC_012633.1 Transcriptional regulator, AbrB family 589140 7814977 RAF_ORF0560 Rickettsia africae ESF-5 Transcriptional regulator, AbrB family YP_002845214.1 588889 R 347255 CDS YP_002845215.1 229586714 7814979 complement(589922..591952) 1 NC_012633.1 Acylamino-acid-releasing enzyme 591952 7814979 RAF_ORF0563 Rickettsia africae ESF-5 Acylamino-acid-releasing enzyme YP_002845215.1 589922 R 347255 CDS YP_002845216.1 229586715 7814980 complement(592040..592675) 1 NC_012633.1 hypothetical protein 592675 7814980 RAF_ORF0564 Rickettsia africae ESF-5 hypothetical protein YP_002845216.1 592040 R 347255 CDS YP_002845217.1 229586716 7814981 complement(593134..593682) 1 NC_012633.1 hypothetical protein 593682 7814981 RAF_ORF0565 Rickettsia africae ESF-5 hypothetical protein YP_002845217.1 593134 R 347255 CDS YP_002845218.1 229586717 7814982 complement(593701..593928) 1 NC_012633.1 hypothetical protein 593928 7814982 RAF_ORF0566 Rickettsia africae ESF-5 hypothetical protein YP_002845218.1 593701 R 347255 CDS YP_002845219.1 229586718 7814983 complement(594105..594467) 1 NC_012633.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 594467 rbfA 7814983 rbfA Rickettsia africae ESF-5 ribosome-binding factor A YP_002845219.1 594105 R 347255 CDS YP_002845220.1 229586719 7814984 complement(594464..594898) 1 NC_012633.1 hypothetical protein 594898 7814984 RAF_ORF0568 Rickettsia africae ESF-5 hypothetical protein YP_002845220.1 594464 R 347255 CDS YP_002845221.1 229586720 7814985 595041..595562 1 NC_012633.1 RDD family protein 595562 7814985 RAF_ORF0569 Rickettsia africae ESF-5 RDD family protein YP_002845221.1 595041 D 347255 CDS YP_002845222.1 229586721 7814986 595710..596315 1 NC_012633.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 596315 recR 7814986 recR Rickettsia africae ESF-5 recombination protein RecR YP_002845222.1 595710 D 347255 CDS YP_002845223.1 229586722 7814987 complement(596913..597680) 1 NC_012633.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 597680 ppnK 7814987 ppnK Rickettsia africae ESF-5 inorganic polyphosphate/ATP-NAD kinase YP_002845223.1 596913 R 347255 CDS YP_002845224.1 229586723 7814988 597764..599446 1 NC_012633.1 Putative hydrolase of the metallo-beta-lactamase superfamily 599446 7814988 RAF_ORF0572 Rickettsia africae ESF-5 Putative hydrolase of the metallo-beta-lactamase superfamily YP_002845224.1 597764 D 347255 CDS YP_002845225.1 229586724 7814989 599586..600563 1 NC_012633.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 600563 gpsA 7814989 gpsA Rickettsia africae ESF-5 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002845225.1 599586 D 347255 CDS YP_002845226.1 229586725 7814990 600788..601717 1 NC_012633.1 Putative permease 601717 7814990 RAF_ORF0574 Rickettsia africae ESF-5 Putative permease YP_002845226.1 600788 D 347255 CDS YP_002845227.1 229586726 7814991 601786..602658 1 NC_012633.1 Putative hydrolase/acyltransferase 602658 7814991 RAF_ORF0575 Rickettsia africae ESF-5 Putative hydrolase/acyltransferase YP_002845227.1 601786 D 347255 CDS YP_002845228.1 229586727 7814992 602860..603792 1 NC_012633.1 Thioredoxin reductase 603792 trxB1 7814992 trxB1 Rickettsia africae ESF-5 Thioredoxin reductase YP_002845228.1 602860 D 347255 CDS YP_002845229.1 229586728 7814993 604012..604308 1 NC_012633.1 hypothetical protein 604308 7814993 RAF_ORF0577 Rickettsia africae ESF-5 hypothetical protein YP_002845229.1 604012 D 347255 CDS YP_002845230.1 229586729 7814994 604963..606390 1 NC_012633.1 succinate semialdehyde dehydrogenase 606390 gabD 7814994 gabD Rickettsia africae ESF-5 succinate semialdehyde dehydrogenase YP_002845230.1 604963 D 347255 CDS YP_002845231.1 229586730 7814995 606886..607731 1 NC_012633.1 Glycosyl transferase 607731 lgtD 7814995 lgtD Rickettsia africae ESF-5 Glycosyl transferase YP_002845231.1 606886 D 347255 CDS YP_002845232.1 229586731 7814996 607809..609770 1 NC_012633.1 DNA helicase II 609770 uvrD 7814996 uvrD Rickettsia africae ESF-5 DNA helicase II YP_002845232.1 607809 D 347255 CDS YP_002845233.1 229586732 7814997 609836..610345 1 NC_012633.1 hypothetical protein 610345 7814997 RAF_ORF0581 Rickettsia africae ESF-5 hypothetical protein YP_002845233.1 609836 D 347255 CDS YP_002845234.1 229586733 7814998 610795..612147 1 NC_012633.1 hypothetical protein 612147 7814998 RAF_ORF0582 Rickettsia africae ESF-5 hypothetical protein YP_002845234.1 610795 D 347255 CDS YP_002845235.1 229586734 7814999 complement(612324..613355) 1 NC_012633.1 catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 613355 tdcB 7814999 tdcB Rickettsia africae ESF-5 threonine dehydratase YP_002845235.1 612324 R 347255 CDS YP_002845236.1 229586735 7815000 613441..615777 1 NC_012633.1 ATP-dependent protease La 615777 lon1 7815000 lon1 Rickettsia africae ESF-5 ATP-dependent protease La YP_002845236.1 613441 D 347255 CDS YP_002845237.1 229586736 7815001 617283..617813 1 NC_012633.1 Cell surface antigen Sca3 617813 sca3 7815001 sca3 Rickettsia africae ESF-5 Cell surface antigen Sca3 YP_002845237.1 617283 D 347255 CDS YP_002845238.1 229586737 7815002 complement(618310..618660) 1 NC_012633.1 hypothetical protein 618660 7815002 RAF_ORF0586 Rickettsia africae ESF-5 hypothetical protein YP_002845238.1 618310 R 347255 CDS YP_002845239.1 229586738 7815004 619326..619634 1 NC_012633.1 hypothetical protein 619634 7815004 RAF_ORF0587 Rickettsia africae ESF-5 hypothetical protein YP_002845239.1 619326 D 347255 CDS YP_002845240.1 229586739 7815005 619751..620329 1 NC_012633.1 Putative sigma(54) modulation protein 620329 yhbH 7815005 yhbH Rickettsia africae ESF-5 Putative sigma(54) modulation protein YP_002845240.1 619751 D 347255 CDS YP_002845241.1 229586740 7815006 620329..620844 1 NC_012633.1 Carbonic anhydrases/acetyltransferase, isoleucine patch superfamily protein 620844 paaY 7815006 paaY Rickettsia africae ESF-5 Carbonic anhydrases/acetyltransferase, isoleucine patch superfamily protein YP_002845241.1 620329 D 347255 CDS YP_002845242.1 229586741 7815007 complement(620875..621741) 1 NC_012633.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 621741 folD 7815007 folD Rickettsia africae ESF-5 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002845242.1 620875 R 347255 CDS YP_002845243.1 229586742 7815008 complement(621878..622900) 1 NC_012633.1 Thioredoxin reductase 622900 trxB2 7815008 trxB2 Rickettsia africae ESF-5 Thioredoxin reductase YP_002845243.1 621878 R 347255 CDS YP_002845244.1 229586743 7815010 625277..625603 1 NC_012633.1 hypothetical protein 625603 7815010 RAF_ORF0595 Rickettsia africae ESF-5 hypothetical protein YP_002845244.1 625277 D 347255 CDS YP_002845245.1 229586744 7815011 626965..628788 1 NC_012633.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 628788 nrdA 7815011 nrdA Rickettsia africae ESF-5 ribonucleotide-diphosphate reductase subunit alpha YP_002845245.1 626965 D 347255 CDS YP_002845246.1 229586745 7815012 628862..629257 1 NC_012633.1 hypothetical protein 629257 7815012 RAF_ORF0597 Rickettsia africae ESF-5 hypothetical protein YP_002845246.1 628862 D 347255 CDS YP_002845247.1 229586746 7815013 629649..630635 1 NC_012633.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 630635 nrdF 7815013 nrdF Rickettsia africae ESF-5 ribonucleotide-diphosphate reductase subunit beta YP_002845247.1 629649 D 347255 CDS YP_002845248.1 229586747 7815014 630778..633660 1 NC_012633.1 hypothetical protein 633660 7815014 RAF_ORF0599 Rickettsia africae ESF-5 hypothetical protein YP_002845248.1 630778 D 347255 CDS YP_002845249.1 229586748 7815016 complement(635743..636777) 1 NC_012633.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 636777 miaA 7815016 miaA Rickettsia africae ESF-5 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002845249.1 635743 R 347255 CDS YP_002845250.1 229586749 7815017 complement(637304..638692) 1 NC_012633.1 phosphomannomutase 638692 exoC 7815017 exoC Rickettsia africae ESF-5 phosphomannomutase YP_002845250.1 637304 R 347255 CDS YP_002845251.1 229586750 7815099 complement(638863..639585) 1 NC_012633.1 ABC transporter ATP-binding protein 639585 abcT2 7815099 abcT2 Rickettsia africae ESF-5 ABC transporter ATP-binding protein YP_002845251.1 638863 R 347255 CDS YP_002845252.1 229586751 7815100 complement(639773..640357) 1 NC_012633.1 hypothetical protein 640357 7815100 RAF_ORF0605 Rickettsia africae ESF-5 hypothetical protein YP_002845252.1 639773 R 347255 CDS YP_002845253.1 229586752 7815101 complement(640326..640922) 1 NC_012633.1 hypothetical protein 640922 7815101 RAF_ORF0606 Rickettsia africae ESF-5 hypothetical protein YP_002845253.1 640326 R 347255 CDS YP_002845254.1 229586753 7815102 complement(640928..641887) 1 NC_012633.1 KpsF 641887 kpsF 7815102 kpsF Rickettsia africae ESF-5 KpsF YP_002845254.1 640928 R 347255 CDS YP_002845255.1 229586754 7815103 complement(642087..644333) 1 NC_012633.1 polynucleotide phosphorylase/polyadenylase 644333 pnp 7815103 pnp Rickettsia africae ESF-5 polynucleotide phosphorylase/polyadenylase YP_002845255.1 642087 R 347255 CDS YP_002845256.1 229586755 7815104 complement(644481..644756) 1 NC_012633.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 644756 rpsO 7815104 rpsO Rickettsia africae ESF-5 30S ribosomal protein S15 YP_002845256.1 644481 R 347255 CDS YP_002845257.1 229586756 7815105 complement(644792..645829) 1 NC_012633.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; proteins in this cluster have Rickettsial repeat elements (RPE) inserts; tRNA pseudouridine synthase B 645829 truB 7815105 truB Rickettsia africae ESF-5 tRNA pseudouridine synthase B YP_002845257.1 644792 R 347255 CDS YP_002845258.1 229586757 7815106 645916..647451 1 NC_012633.1 ATP/ADP translocase 647451 tlc4 7815106 tlc4 Rickettsia africae ESF-5 ATP/ADP translocase YP_002845258.1 645916 D 347255 CDS YP_002845259.1 229586758 7815107 647729..650815 1 NC_012633.1 Cell surface antigen Sca4 650815 sca4 7815107 sca4 Rickettsia africae ESF-5 Cell surface antigen Sca4 YP_002845259.1 647729 D 347255 CDS YP_002845260.1 229586759 7815108 complement(650934..651311) 1 NC_012633.1 Putative transcriptional regulator 651311 hipB 7815108 hipB Rickettsia africae ESF-5 Putative transcriptional regulator YP_002845260.1 650934 R 347255 CDS YP_002845261.1 229586760 7815109 651835..652662 1 NC_012633.1 Putative ribonuclease BN 652662 rbn 7815109 rbn Rickettsia africae ESF-5 Putative ribonuclease BN YP_002845261.1 651835 D 347255 CDS YP_002845262.1 229586761 7815110 complement(652811..653644) 1 NC_012633.1 glutamine synthetase 653644 glnA 7815110 glnA Rickettsia africae ESF-5 glutamine synthetase YP_002845262.1 652811 R 347255 CDS YP_002845263.1 229586762 7815111 653643..654365 1 NC_012633.1 hypothetical protein 654365 7815111 RAF_ORF0616 Rickettsia africae ESF-5 hypothetical protein YP_002845263.1 653643 D 347255 CDS YP_002845264.1 229586763 7815112 654658..655209 1 NC_012633.1 Polypeptide deformylase 655209 def2 7815112 def2 Rickettsia africae ESF-5 Polypeptide deformylase YP_002845264.1 654658 D 347255 CDS YP_002845265.1 229586764 7815113 655420..655617 1 NC_012633.1 Antitoxin of toxin-antitoxin (TA) system Phd 655617 7815113 RAF_ORF0618 Rickettsia africae ESF-5 Antitoxin of toxin-antitoxin (TA) system Phd YP_002845265.1 655420 D 347255 CDS YP_002845266.1 229586765 7815114 655679..656083 1 NC_012633.1 Toxin of toxin-antitoxin (TA) system, containing PIN domain for nucleic acid binding 656083 7815114 RAF_ORF0619 Rickettsia africae ESF-5 Toxin of toxin-antitoxin (TA) system, containing PIN domain for nucleic acid binding YP_002845266.1 655679 D 347255 CDS YP_002845267.1 229586766 7815115 complement(656084..656779) 1 NC_012633.1 hypothetical protein 656779 addA 7815115 addA Rickettsia africae ESF-5 hypothetical protein YP_002845267.1 656084 R 347255 CDS YP_002845268.1 229586767 7815116 complement(657015..658823) 1 NC_012633.1 hypothetical protein 658823 7815116 RAF_ORF0621 Rickettsia africae ESF-5 hypothetical protein YP_002845268.1 657015 R 347255 CDS YP_002845269.1 229586768 7815117 complement(659077..661713) 1 NC_012633.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 661713 ppdK 7815117 ppdK Rickettsia africae ESF-5 pyruvate phosphate dikinase YP_002845269.1 659077 R 347255 CDS YP_002845270.1 229586769 7815119 662644..663312 1 NC_012633.1 glutathione S-transferase 663312 7815119 RAF_ORF0623 Rickettsia africae ESF-5 glutathione S-transferase YP_002845270.1 662644 D 347255 CDS YP_002845271.1 229586770 7815120 complement(663424..664176) 1 NC_012633.1 biotin--protein ligase 664176 bpl1 7815120 bpl1 Rickettsia africae ESF-5 biotin--protein ligase YP_002845271.1 663424 R 347255 CDS YP_002845272.1 229586771 7815121 664252..664794 1 NC_012633.1 BioY family protein 664794 bioY2 7815121 bioY2 Rickettsia africae ESF-5 BioY family protein YP_002845272.1 664252 D 347255 CDS YP_002845273.1 229586772 7815122 664996..666276 1 NC_012633.1 Folylpolyglutamate synthase 666276 folC 7815122 folC Rickettsia africae ESF-5 Folylpolyglutamate synthase YP_002845273.1 664996 D 347255 CDS YP_002845274.1 229586773 7815123 666447..667076 1 NC_012633.1 Superoxide dismutase 667076 sodB 7815123 sodB Rickettsia africae ESF-5 Superoxide dismutase YP_002845274.1 666447 D 347255 CDS YP_002845275.1 229586774 7815125 668993..669805 1 NC_012633.1 Biotin-(acetyl-CoA carboxylase) ligase 669805 birA 7815125 birA Rickettsia africae ESF-5 Biotin-(acetyl-CoA carboxylase) ligase YP_002845275.1 668993 D 347255 CDS YP_002845276.1 229586775 7815126 670242..670754 1 NC_012633.1 hypothetical protein 670754 7815126 RAF_ORF0633 Rickettsia africae ESF-5 hypothetical protein YP_002845276.1 670242 D 347255 CDS YP_002845277.1 229586776 7815127 670751..671035 1 NC_012633.1 hypothetical protein 671035 7815127 RAF_ORF0634 Rickettsia africae ESF-5 hypothetical protein YP_002845277.1 670751 D 347255 CDS YP_002845278.1 229586777 7815128 671050..671220 1 NC_012633.1 hypothetical protein 671220 7815128 RAF_ORF0635 Rickettsia africae ESF-5 hypothetical protein YP_002845278.1 671050 D 347255 CDS YP_002845279.1 229586778 7815129 671224..671397 1 NC_012633.1 hypothetical protein 671397 7815129 RAF_ORF0636 Rickettsia africae ESF-5 hypothetical protein YP_002845279.1 671224 D 347255 CDS YP_002845280.1 229586779 7815130 671384..671713 1 NC_012633.1 hypothetical protein 671713 7815130 RAF_ORF0637 Rickettsia africae ESF-5 hypothetical protein YP_002845280.1 671384 D 347255 CDS YP_002845281.1 229586780 7815131 671864..672337 1 NC_012633.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 672337 infC 7815131 infC Rickettsia africae ESF-5 translation initiation factor IF-3 YP_002845281.1 671864 D 347255 CDS YP_002845282.1 229586781 7815132 672472..673710 1 NC_012633.1 branched-chain alpha-keto acid dehydrogenase subunit E2 673710 pdhC 7815132 pdhC Rickettsia africae ESF-5 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_002845282.1 672472 D 347255 CDS YP_002845283.1 229586782 7815133 673843..674910 1 NC_012633.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 674910 prfA 7815133 prfA Rickettsia africae ESF-5 peptide chain release factor 1 YP_002845283.1 673843 D 347255 CDS YP_002845284.1 229586783 7815134 complement(675047..675250) 1 NC_012633.1 hypothetical protein 675250 7815134 RAF_ORF0641 Rickettsia africae ESF-5 hypothetical protein YP_002845284.1 675047 R 347255 CDS YP_002845285.1 229586784 7815135 complement(675240..675464) 1 NC_012633.1 hypothetical protein 675464 7815135 RAF_ORF0642 Rickettsia africae ESF-5 hypothetical protein YP_002845285.1 675240 R 347255 CDS YP_002845286.1 229586785 7815136 676966..678729 1 NC_012633.1 ssDNA-specific exonuclease RecJ 678729 recJ 7815136 recJ Rickettsia africae ESF-5 ssDNA-specific exonuclease RecJ YP_002845286.1 676966 D 347255 CDS YP_002845287.1 229586786 7815137 678773..680095 1 NC_012633.1 Putative methyltransferase 680095 7815137 RAF_ORF0644 Rickettsia africae ESF-5 Putative methyltransferase YP_002845287.1 678773 D 347255 CDS YP_002845288.1 229586787 7815138 680480..681856 1 NC_012633.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 681856 rho 7815138 rho Rickettsia africae ESF-5 transcription termination factor Rho YP_002845288.1 680480 D 347255 CDS YP_002845289.1 229586788 7815139 681981..682895 1 NC_012633.1 signal peptide peptidase SppA 682895 sppA2 7815139 sppA2 Rickettsia africae ESF-5 signal peptide peptidase SppA YP_002845289.1 681981 D 347255 CDS YP_002845290.1 229586789 7815140 682898..683140 1 NC_012633.1 Integration host factor beta-subunit 683140 himD 7815140 himD Rickettsia africae ESF-5 Integration host factor beta-subunit YP_002845290.1 682898 D 347255 CDS YP_002845291.1 229586790 7815141 683905..684651 1 NC_012633.1 hypothetical protein 684651 7815141 RAF_ORF0648 Rickettsia africae ESF-5 hypothetical protein YP_002845291.1 683905 D 347255 CDS YP_002845292.1 229586791 7815142 684989..685444 1 NC_012633.1 hypothetical protein 685444 7815142 RAF_ORF0649 Rickettsia africae ESF-5 hypothetical protein YP_002845292.1 684989 D 347255 CDS YP_002845293.1 229586792 7815143 685753..686274 1 NC_012633.1 Putative conjugative transfer protein TraD 686274 traD_F 7815143 traD_F Rickettsia africae ESF-5 Putative conjugative transfer protein TraD YP_002845293.1 685753 D 347255 CDS YP_002845294.1 229586793 7815144 complement(686516..686860) 1 NC_012633.1 Transposase and inactivated derivative 686860 7815144 RAF_ORF0651 Rickettsia africae ESF-5 Transposase and inactivated derivative YP_002845294.1 686516 R 347255 CDS YP_002845295.1 229586794 7815145 complement(686799..687311) 1 NC_012633.1 Guanosine polyphosphate pyrophosphohydrolase/synthetase 687311 spoT15 7815145 spoT15 Rickettsia africae ESF-5 Guanosine polyphosphate pyrophosphohydrolase/synthetase YP_002845295.1 686799 R 347255 CDS YP_002845296.1 229586795 7815149 692424..693236 1 NC_012633.1 Site-specific DNA adenine methylase 693236 dam2 7815149 dam2 Rickettsia africae ESF-5 Site-specific DNA adenine methylase YP_002845296.1 692424 D 347255 CDS YP_002845297.1 229586796 7815150 complement(693238..694944) 1 NC_012633.1 hypothetical protein 694944 7815150 RAF_ORF0660 Rickettsia africae ESF-5 hypothetical protein YP_002845297.1 693238 R 347255 CDS YP_002845298.1 229586797 7815152 695380..695556 1 NC_012633.1 hypothetical protein 695556 7815152 RAF_ORF0661 Rickettsia africae ESF-5 hypothetical protein YP_002845298.1 695380 D 347255 CDS YP_002845299.1 229586798 7815153 695780..696439 1 NC_012633.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 696439 cmk 7815153 cmk Rickettsia africae ESF-5 cytidylate kinase YP_002845299.1 695780 D 347255 CDS YP_002845300.1 229586799 7815154 696695..698401 1 NC_012633.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 698401 rpsA 7815154 rpsA Rickettsia africae ESF-5 30S ribosomal protein S1 YP_002845300.1 696695 D 347255 CDS YP_002845301.1 229586800 7815155 698516..699166 1 NC_012633.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 699166 clpP 7815155 clpP Rickettsia africae ESF-5 ATP-dependent Clp protease proteolytic subunit YP_002845301.1 698516 D 347255 CDS YP_002845302.1 229586801 7815157 700101..701129 1 NC_012633.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 701129 fni 7815157 fni Rickettsia africae ESF-5 isopentenyl pyrophosphate isomerase YP_002845302.1 700101 D 347255 CDS YP_002845303.1 229586802 7815158 complement(701219..701440) 1 NC_012633.1 Putative acetyltransferase 701440 7815158 RAF_ORF0666 Rickettsia africae ESF-5 Putative acetyltransferase YP_002845303.1 701219 R 347255 CDS YP_002845304.1 229586803 7815159 complement(701474..701689) 1 NC_012633.1 hypothetical protein 701689 7815159 RAF_ORF0667 Rickettsia africae ESF-5 hypothetical protein YP_002845304.1 701474 R 347255 CDS YP_002845305.1 229586804 7815160 complement(701686..702135) 1 NC_012633.1 Acetyltransferase GNAT family protein 702135 7815160 RAF_ORF0668 Rickettsia africae ESF-5 Acetyltransferase GNAT family protein YP_002845305.1 701686 R 347255 CDS YP_002845306.1 229586805 7815161 complement(702330..702665) 1 NC_012633.1 hypothetical protein 702665 7815161 RAF_ORF0669 Rickettsia africae ESF-5 hypothetical protein YP_002845306.1 702330 R 347255 CDS YP_002845307.1 229586806 7815162 703348..703515 1 NC_012633.1 hypothetical protein 703515 7815162 RAF_ORF0670 Rickettsia africae ESF-5 hypothetical protein YP_002845307.1 703348 D 347255 CDS YP_002845308.1 229586807 7815163 703808..704680 1 NC_012633.1 hypothetical protein 704680 7815163 RAF_ORF0671 Rickettsia africae ESF-5 hypothetical protein YP_002845308.1 703808 D 347255 CDS YP_002845309.1 229586808 7815165 705927..706346 1 NC_012633.1 Iron-sulfur cluster assembly transcription factor IscR 706346 iscR 7815165 iscR Rickettsia africae ESF-5 Iron-sulfur cluster assembly transcription factor IscR YP_002845309.1 705927 D 347255 CDS YP_002845310.1 229586809 7815166 706343..707461 1 NC_012633.1 NifS-like protein 707461 spl1 7815166 spl1 Rickettsia africae ESF-5 NifS-like protein YP_002845310.1 706343 D 347255 CDS YP_002845311.1 229586810 7815167 707564..708796 1 NC_012633.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 708796 iscS 7815167 iscS Rickettsia africae ESF-5 cysteine desulfurase YP_002845311.1 707564 D 347255 CDS YP_002845312.1 229586811 7815168 708948..709343 1 NC_012633.1 scaffold protein 709343 iscU 7815168 iscU Rickettsia africae ESF-5 scaffold protein YP_002845312.1 708948 D 347255 CDS YP_002845313.1 229586812 7815169 709347..709679 1 NC_012633.1 Iron-sulfur cluster assembly accessory protein 709679 iscA2 7815169 iscA2 Rickettsia africae ESF-5 Iron-sulfur cluster assembly accessory protein YP_002845313.1 709347 D 347255 CDS YP_002845314.1 229586813 7815170 complement(710201..710380) 1 NC_012633.1 lysozyme 710380 7815170 RAF_ORF0679 Rickettsia africae ESF-5 lysozyme YP_002845314.1 710201 R 347255 CDS YP_002845315.1 229586814 7815171 710528..711811 1 NC_012633.1 Putrescine-ornithine antiporter 711811 potE 7815171 potE Rickettsia africae ESF-5 Putrescine-ornithine antiporter YP_002845315.1 710528 D 347255 CDS YP_002845316.1 229586815 7815172 711953..713791 1 NC_012633.1 Aminopeptidase P 713791 pepP 7815172 pepP Rickettsia africae ESF-5 Aminopeptidase P YP_002845316.1 711953 D 347255 CDS YP_002845317.1 229586816 7815175 complement(714090..715205) 1 NC_012633.1 Octaprenyl-diphosphate synthase 715205 ispB 7815175 ispB Rickettsia africae ESF-5 Octaprenyl-diphosphate synthase YP_002845317.1 714090 R 347255 CDS YP_002845318.1 229586817 7815659 complement(715192..716850) 1 NC_012633.1 hypothetical protein 716850 7815659 RAF_ORF0683 Rickettsia africae ESF-5 hypothetical protein YP_002845318.1 715192 R 347255 CDS YP_002845319.1 229586818 7815660 complement(717044..718549) 1 NC_012633.1 ATP/ADP translocase 718549 tlc3 7815660 tlc3 Rickettsia africae ESF-5 ATP/ADP translocase YP_002845319.1 717044 R 347255 CDS YP_002845320.1 229586819 7815662 719104..719241 1 NC_012633.1 hypothetical protein 719241 7815662 RAF_ORF0687 Rickettsia africae ESF-5 hypothetical protein YP_002845320.1 719104 D 347255 CDS YP_002845321.1 229586820 7815663 719584..720837 1 NC_012633.1 AmpG protein 720837 ampG1 7815663 ampG1 Rickettsia africae ESF-5 AmpG protein YP_002845321.1 719584 D 347255 CDS YP_002845322.1 229586821 7815664 721432..722073 1 NC_012633.1 Lysine efflux permease 722073 lysE 7815664 lysE Rickettsia africae ESF-5 Lysine efflux permease YP_002845322.1 721432 D 347255 CDS YP_002845323.1 229586822 7815665 722021..722725 1 NC_012633.1 hypothetical protein 722725 7815665 RAF_ORF0690 Rickettsia africae ESF-5 hypothetical protein YP_002845323.1 722021 D 347255 CDS YP_002845324.1 229586823 7815666 722709..723464 1 NC_012633.1 hypothetical protein 723464 7815666 RAF_ORF0691 Rickettsia africae ESF-5 hypothetical protein YP_002845324.1 722709 D 347255 CDS YP_002845325.1 229586824 7815667 723457..724461 1 NC_012633.1 HemY-like protein 724461 7815667 RAF_ORF0692 Rickettsia africae ESF-5 HemY-like protein YP_002845325.1 723457 D 347255 CDS YP_002845326.1 229586825 7815668 complement(724680..725399) 1 NC_012633.1 Putative hydrolase of the alpha/beta superfamily 725399 7815668 RAF_ORF0693 Rickettsia africae ESF-5 Putative hydrolase of the alpha/beta superfamily YP_002845326.1 724680 R 347255 CDS YP_002845327.1 229586826 7815669 725630..725767 1 NC_012633.1 DNA-damage-inducible protein J 725767 relB2 7815669 relB2 Rickettsia africae ESF-5 DNA-damage-inducible protein J YP_002845327.1 725630 D 347255 CDS YP_002845328.1 229586827 7815670 complement(726118..726570) 1 NC_012633.1 AtsE-like protein 726570 7815670 RAF_ORF0695 Rickettsia africae ESF-5 AtsE-like protein YP_002845328.1 726118 R 347255 CDS YP_002845329.1 229586828 7815671 complement(726623..727348) 1 NC_012633.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 727348 plsC 7815671 plsC Rickettsia africae ESF-5 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002845329.1 726623 R 347255 CDS YP_002845330.1 229586829 7815672 727426..728418 1 NC_012633.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 728418 trpS 7815672 trpS Rickettsia africae ESF-5 tryptophanyl-tRNA synthetase YP_002845330.1 727426 D 347255 CDS YP_002845331.1 229586830 7815674 complement(729338..729538) 1 NC_012633.1 AAA ATPase 729538 7815674 RAF_ORF0698 Rickettsia africae ESF-5 AAA ATPase YP_002845331.1 729338 R 347255 CDS YP_002845332.1 229586831 7815675 complement(730349..731404) 1 NC_012633.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 731404 hemC 7815675 hemC Rickettsia africae ESF-5 porphobilinogen deaminase YP_002845332.1 730349 R 347255 CDS YP_002845333.1 229586832 7815676 complement(731401..732390) 1 NC_012633.1 Microcin C7 resistance protein 732390 mccF2 7815676 mccF2 Rickettsia africae ESF-5 Microcin C7 resistance protein YP_002845333.1 731401 R 347255 CDS YP_002845334.1 229586833 7815677 complement(733050..734885) 1 NC_012633.1 Na+/proline symporter and signal transduction histidine kinase 734885 putP 7815677 putP Rickettsia africae ESF-5 Na+/proline symporter and signal transduction histidine kinase YP_002845334.1 733050 R 347255 CDS YP_002845335.1 229586834 7815678 complement(735584..736099) 1 NC_012633.1 Ankyrin repeat protein 736099 7815678 RAF_ORF0702 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002845335.1 735584 R 347255 CDS YP_002845336.1 229586835 7815679 complement(736117..736455) 1 NC_012633.1 hypothetical protein 736455 7815679 RAF_ORF0703 Rickettsia africae ESF-5 hypothetical protein YP_002845336.1 736117 R 347255 CDS YP_002845337.1 229586836 7815680 complement(736776..737783) 1 NC_012633.1 GcvT-like putative aminomethyltransferase 737783 7815680 RAF_ORF0704 Rickettsia africae ESF-5 GcvT-like putative aminomethyltransferase YP_002845337.1 736776 R 347255 CDS YP_002845338.1 229586837 7815681 737857..738687 1 NC_012633.1 hypothetical protein 738687 7815681 RAF_ORF0705 Rickettsia africae ESF-5 hypothetical protein YP_002845338.1 737857 D 347255 CDS YP_002845339.1 229586838 7815682 738697..739542 1 NC_012633.1 Ribonuclease D 739542 rnd 7815682 rnd Rickettsia africae ESF-5 Ribonuclease D YP_002845339.1 738697 D 347255 CDS YP_002845340.1 229586839 7815683 complement(739918..740460) 1 NC_012633.1 5-formyltetrahydrofolate cyclo-ligase 740460 7815683 RAF_ORF0707 Rickettsia africae ESF-5 5-formyltetrahydrofolate cyclo-ligase YP_002845340.1 739918 R 347255 CDS YP_002845341.1 229586840 7815684 complement(740729..742108) 1 NC_012633.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 742108 lpdA2 7815684 lpdA2 Rickettsia africae ESF-5 dihydrolipoamide dehydrogenase YP_002845341.1 740729 R 347255 CDS YP_002845342.1 229586841 7815685 complement(742261..742941) 1 NC_012633.1 hypothetical protein 742941 7815685 RAF_ORF0709 Rickettsia africae ESF-5 hypothetical protein YP_002845342.1 742261 R 347255 CDS YP_002845343.1 229586842 7815686 complement(743156..743467) 1 NC_012633.1 hypothetical protein 743467 7815686 RAF_ORF0710 Rickettsia africae ESF-5 hypothetical protein YP_002845343.1 743156 R 347255 CDS YP_002845344.1 229586843 7815687 complement(743559..744107) 1 NC_012633.1 Site-specific DNA methylase 744107 dam1 7815687 dam1 Rickettsia africae ESF-5 Site-specific DNA methylase YP_002845344.1 743559 R 347255 CDS YP_002845345.1 229586844 7815688 complement(744570..745271) 1 NC_012633.1 Transposase and inactivated derivative 745271 7815688 RAF_ORF0712 Rickettsia africae ESF-5 Transposase and inactivated derivative YP_002845345.1 744570 R 347255 CDS YP_002845346.1 229586845 7815689 complement(745578..746063) 1 NC_012633.1 hypothetical protein 746063 7815689 RAF_ORF0713 Rickettsia africae ESF-5 hypothetical protein YP_002845346.1 745578 R 347255 CDS YP_002845347.1 229586846 7815690 complement(746068..746910) 1 NC_012633.1 lytic murein transglycosylase 746910 mltE2 7815690 mltE2 Rickettsia africae ESF-5 lytic murein transglycosylase YP_002845347.1 746068 R 347255 CDS YP_002845348.1 229586847 7815691 complement(747205..747465) 1 NC_012633.1 hypothetical protein 747465 7815691 RAF_ORF0715 Rickettsia africae ESF-5 hypothetical protein YP_002845348.1 747205 R 347255 CDS YP_002845349.1 229586848 7815692 748337..748462 1 NC_012633.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 748462 rpmJ 7815692 rpmJ Rickettsia africae ESF-5 50S ribosomal protein L36 YP_002845349.1 748337 D 347255 CDS YP_002845350.1 229586849 7815693 748671..749432 1 NC_012633.1 hypothetical protein 749432 7815693 RAF_ORF0717 Rickettsia africae ESF-5 hypothetical protein YP_002845350.1 748671 D 347255 CDS YP_002845351.1 229586850 7815694 749429..750175 1 NC_012633.1 UDP-N-acetylglucosamine pyrophosphorylase 750175 glmU 7815694 glmU Rickettsia africae ESF-5 UDP-N-acetylglucosamine pyrophosphorylase YP_002845351.1 749429 D 347255 CDS YP_002845352.1 229586851 7815696 complement(750657..750881) 1 NC_012633.1 hypothetical protein 750881 7815696 RAF_ORF0719 Rickettsia africae ESF-5 hypothetical protein YP_002845352.1 750657 R 347255 CDS YP_002845353.1 229586852 7815697 complement(752722..753039) 1 NC_012633.1 hypothetical protein 753039 7815697 RAF_ORF0720 Rickettsia africae ESF-5 hypothetical protein YP_002845353.1 752722 R 347255 CDS YP_002845354.1 229586853 7815698 complement(753026..753388) 1 NC_012633.1 MazG-like protein 753388 mazG 7815698 mazG Rickettsia africae ESF-5 MazG-like protein YP_002845354.1 753026 R 347255 CDS YP_002845355.1 229586854 7815699 complement(753469..753786) 1 NC_012633.1 hypothetical protein 753786 7815699 RAF_ORF0722 Rickettsia africae ESF-5 hypothetical protein YP_002845355.1 753469 R 347255 CDS YP_002845356.1 229586855 7815700 754324..754485 1 NC_012633.1 hypothetical protein 754485 7815700 RAF_ORF0723 Rickettsia africae ESF-5 hypothetical protein YP_002845356.1 754324 D 347255 CDS YP_002845357.1 229586856 7815701 complement(755189..755761) 1 NC_012633.1 hypothetical protein 755761 7815701 RAF_ORF0724 Rickettsia africae ESF-5 hypothetical protein YP_002845357.1 755189 R 347255 CDS YP_002845358.1 229586857 7815702 complement(756107..756319) 1 NC_012633.1 NACHT family NTPase 756319 7815702 RAF_ORF0725 Rickettsia africae ESF-5 NACHT family NTPase YP_002845358.1 756107 R 347255 CDS YP_002845359.1 229586858 7815703 757598..758974 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 758974 nuoN1 7815703 nuoN1 Rickettsia africae ESF-5 NADH dehydrogenase subunit N YP_002845359.1 757598 D 347255 CDS YP_002845360.1 229586859 7815704 complement(758961..760502) 1 NC_012633.1 hypothetical protein 760502 7815704 RAF_ORF0727 Rickettsia africae ESF-5 hypothetical protein YP_002845360.1 758961 R 347255 CDS YP_002845361.1 229586860 7815705 complement(760591..761592) 1 NC_012633.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 761592 hemB 7815705 hemB Rickettsia africae ESF-5 delta-aminolevulinic acid dehydratase YP_002845361.1 760591 R 347255 CDS YP_002845362.1 229586861 7815707 complement(762781..764727) 1 NC_012633.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 764727 priA 7815707 priA Rickettsia africae ESF-5 primosome assembly protein PriA YP_002845362.1 762781 R 347255 CDS YP_002845363.1 229586862 7815708 764791..765366 1 NC_012633.1 aromatic acid decarboxylase 765366 ubiX 7815708 ubiX Rickettsia africae ESF-5 aromatic acid decarboxylase YP_002845363.1 764791 D 347255 CDS YP_002845364.1 229586863 7815709 765733..767217 1 NC_012633.1 unwinds double stranded DNA; replicative DNA helicase 767217 dnaB 7815709 dnaB Rickettsia africae ESF-5 replicative DNA helicase YP_002845364.1 765733 D 347255 CDS YP_002845365.1 229586864 7815710 complement(768058..768213) 1 NC_012633.1 amino acid permease 768213 7815710 RAF_ORF0735 Rickettsia africae ESF-5 amino acid permease YP_002845365.1 768058 R 347255 CDS YP_002845366.1 229586865 7815711 769085..769777 1 NC_012633.1 Ribosomal large subunit pseudouridine synthase 769777 rluA2 7815711 rluA2 Rickettsia africae ESF-5 Ribosomal large subunit pseudouridine synthase YP_002845366.1 769085 D 347255 CDS YP_002845367.1 229586866 7815712 769824..772697 1 NC_012633.1 hypothetical protein 772697 7815712 RAF_ORF0737 Rickettsia africae ESF-5 hypothetical protein YP_002845367.1 769824 D 347255 CDS YP_002845368.1 229586867 7815713 772702..773439 1 NC_012633.1 N6-adenine-specific methylase 773439 7815713 RAF_ORF0738 Rickettsia africae ESF-5 N6-adenine-specific methylase YP_002845368.1 772702 D 347255 CDS YP_002845369.1 229586868 7815714 773585..774919 1 NC_012633.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 774919 radA 7815714 radA Rickettsia africae ESF-5 DNA repair protein RadA YP_002845369.1 773585 D 347255 CDS YP_002845370.1 229586869 7815715 774916..775230 1 NC_012633.1 hypothetical protein 775230 7815715 RAF_ORF0740 Rickettsia africae ESF-5 hypothetical protein YP_002845370.1 774916 D 347255 CDS YP_002845371.1 229586870 7815716 775351..776064 1 NC_012633.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 776064 recO 7815716 recO Rickettsia africae ESF-5 DNA repair protein RecO YP_002845371.1 775351 D 347255 CDS YP_002845372.1 229586871 7815717 776513..777211 1 NC_012633.1 Putative glycoprotein endopeptidase 777211 7815717 RAF_ORF0742 Rickettsia africae ESF-5 Putative glycoprotein endopeptidase YP_002845372.1 776513 D 347255 CDS YP_002845373.1 229586872 7815718 complement(777262..778035) 1 NC_012633.1 hypothetical protein 778035 7815718 RAF_ORF0743 Rickettsia africae ESF-5 hypothetical protein YP_002845373.1 777262 R 347255 CDS YP_002845374.1 229586873 7815719 complement(778883..781378) 1 NC_012633.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 781378 infB 7815719 infB Rickettsia africae ESF-5 translation initiation factor IF-2 YP_002845374.1 778883 R 347255 CDS YP_002845375.1 229586874 7815720 complement(781618..783129) 1 NC_012633.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 783129 nusA 7815720 nusA Rickettsia africae ESF-5 transcription elongation factor NusA YP_002845375.1 781618 R 347255 CDS YP_002845376.1 229586875 7815721 complement(783140..783625) 1 NC_012633.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 783625 7815721 RAF_ORF0746 Rickettsia africae ESF-5 hypothetical protein YP_002845376.1 783140 R 347255 CDS YP_002845377.1 229586876 7815722 complement(784747..785040) 1 NC_012633.1 hypothetical protein 785040 7815722 RAF_ORF0747 Rickettsia africae ESF-5 hypothetical protein YP_002845377.1 784747 R 347255 CDS YP_002845378.1 229586877 7815723 785162..785590 1 NC_012633.1 Putative transcriptional regulator 785590 7815723 RAF_ORF0748 Rickettsia africae ESF-5 Putative transcriptional regulator YP_002845378.1 785162 D 347255 CDS YP_002845379.1 229586878 7815724 complement(785585..786340) 1 NC_012633.1 Hemolysin A 786340 tlyA 7815724 tlyA Rickettsia africae ESF-5 Hemolysin A YP_002845379.1 785585 R 347255 CDS YP_002845380.1 229586879 7815725 complement(786499..787734) 1 NC_012633.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 787734 tyrS 7815725 tyrS Rickettsia africae ESF-5 tyrosyl-tRNA synthetase YP_002845380.1 786499 R 347255 CDS YP_002845381.1 229586880 7815726 complement(787821..788018) 1 NC_012633.1 hypothetical protein 788018 7815726 RAF_ORF0751 Rickettsia africae ESF-5 hypothetical protein YP_002845381.1 787821 R 347255 CDS YP_002845382.1 229586881 7815727 complement(788024..788188) 1 NC_012633.1 hypothetical protein 788188 7815727 RAF_ORF0752 Rickettsia africae ESF-5 hypothetical protein YP_002845382.1 788024 R 347255 CDS YP_002845383.1 229586882 7815728 788343..788636 1 NC_012633.1 hypothetical protein 788636 7815728 RAF_ORF0753 Rickettsia africae ESF-5 hypothetical protein YP_002845383.1 788343 D 347255 CDS YP_002845384.1 229586883 7815730 complement(790437..790916) 1 NC_012633.1 hypothetical protein 790916 7815730 RAF_ORF0754 Rickettsia africae ESF-5 hypothetical protein YP_002845384.1 790437 R 347255 CDS YP_002845385.1 229586884 7815731 complement(791376..791732) 1 NC_012633.1 hypothetical protein 791732 7815731 RAF_ORF0755 Rickettsia africae ESF-5 hypothetical protein YP_002845385.1 791376 R 347255 CDS YP_002845386.1 229586885 7815732 complement(792498..793076) 1 NC_012633.1 hypothetical protein 793076 7815732 RAF_ORF0756 Rickettsia africae ESF-5 hypothetical protein YP_002845386.1 792498 R 347255 CDS YP_002845387.1 229586886 7815733 complement(793169..793396) 1 NC_012633.1 Proline/betaine transporter 793396 proP8 7815733 proP8 Rickettsia africae ESF-5 Proline/betaine transporter YP_002845387.1 793169 R 347255 CDS YP_002845388.1 229586887 7815734 complement(793518..793919) 1 NC_012633.1 hypothetical protein 793919 7815734 RAF_ORF0758 Rickettsia africae ESF-5 hypothetical protein YP_002845388.1 793518 R 347255 CDS YP_002845389.1 229586888 7815735 794375..800053 1 NC_012633.1 Large extracellular alpha-helical protein 800053 7815735 RAF_ORF0759 Rickettsia africae ESF-5 Large extracellular alpha-helical protein YP_002845389.1 794375 D 347255 CDS YP_002845390.1 229586889 7815737 complement(802506..802871) 1 NC_012633.1 Competence protein F 802871 comF2 7815737 comF2 Rickettsia africae ESF-5 Competence protein F YP_002845390.1 802506 R 347255 CDS YP_002845391.1 229586890 7815738 complement(802864..803211) 1 NC_012633.1 Competence protein F 803211 comF1 7815738 comF1 Rickettsia africae ESF-5 Competence protein F YP_002845391.1 802864 R 347255 CDS YP_002845392.1 229586891 7814856 complement(804550..804816) 1 NC_012633.1 hypothetical protein 804816 7814856 RAF_ORF0770 Rickettsia africae ESF-5 hypothetical protein YP_002845392.1 804550 R 347255 CDS YP_002845393.1 229586892 7815579 complement(804994..806289) 1 NC_012633.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 806289 ubiH 7815579 ubiH Rickettsia africae ESF-5 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002845393.1 804994 R 347255 CDS YP_002845394.1 229586893 7815580 complement(806261..806527) 1 NC_012633.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit F 806527 7815580 RAF_ORF0772 Rickettsia africae ESF-5 putative monovalent cation/H+ antiporter subunit F YP_002845394.1 806261 R 347255 CDS YP_002845395.1 229586894 7815581 807044..808468 1 NC_012633.1 Nitrogen assimilation regulatory protein NtrX 808468 ntrX 7815581 ntrX Rickettsia africae ESF-5 Nitrogen assimilation regulatory protein NtrX YP_002845395.1 807044 D 347255 CDS YP_002845396.1 229586895 7815582 808437..810206 1 NC_012633.1 hypothetical protein 810206 7815582 RAF_ORF0774 Rickettsia africae ESF-5 hypothetical protein YP_002845396.1 808437 D 347255 CDS YP_002845397.1 229586896 7815583 complement(810428..811387) 1 NC_012633.1 hypothetical protein 811387 7815583 RAF_ORF0775 Rickettsia africae ESF-5 hypothetical protein YP_002845397.1 810428 R 347255 CDS YP_002845398.1 229586897 7815584 complement(812063..813844) 1 NC_012633.1 Penicillin-binding protein 813844 pbpA1 7815584 pbpA1 Rickettsia africae ESF-5 Penicillin-binding protein YP_002845398.1 812063 R 347255 CDS YP_002845399.1 229586898 7815585 complement(813834..814355) 1 NC_012633.1 hypothetical protein 814355 7815585 RAF_ORF0777 Rickettsia africae ESF-5 hypothetical protein YP_002845399.1 813834 R 347255 CDS YP_002845400.1 229586899 7815586 complement(814974..816656) 1 NC_012633.1 Penicillin-binding protein 816656 pbpA2 7815586 pbpA2 Rickettsia africae ESF-5 Penicillin-binding protein YP_002845400.1 814974 R 347255 CDS YP_002845401.1 229586900 7815587 complement(817000..817398) 1 NC_012633.1 Cell division protein FtsL 817398 ftsL 7815587 ftsL Rickettsia africae ESF-5 Cell division protein FtsL YP_002845401.1 817000 R 347255 CDS YP_002845402.1 229586901 7815588 complement(817405..818328) 1 NC_012633.1 S-adenosyl-methyltransferase MraW 818328 mraW 7815588 mraW Rickettsia africae ESF-5 S-adenosyl-methyltransferase MraW YP_002845402.1 817405 R 347255 CDS YP_002845403.1 229586902 7815589 complement(818328..818777) 1 NC_012633.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 818777 mraZ 7815589 mraZ Rickettsia africae ESF-5 cell division protein MraZ YP_002845403.1 818328 R 347255 CDS YP_002845404.1 229586903 7815590 819191..819709 1 NC_012633.1 Ankyrin repeat protein 819709 7815590 RAF_ORF0782 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002845404.1 819191 D 347255 CDS YP_002845405.1 229586904 7815591 820358..821755 1 NC_012633.1 Sodium/pantothenate symporter 821755 panF 7815591 panF Rickettsia africae ESF-5 Sodium/pantothenate symporter YP_002845405.1 820358 D 347255 CDS YP_002845406.1 229586905 7815592 complement(822382..824301) 1 NC_012633.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 824301 uvrC 7815592 uvrC Rickettsia africae ESF-5 excinuclease ABC subunit C YP_002845406.1 822382 R 347255 CDS YP_002845407.1 229586906 7815593 complement(824476..825009) 1 NC_012633.1 hypothetical protein 825009 7815593 RAF_ORF0785 Rickettsia africae ESF-5 hypothetical protein YP_002845407.1 824476 R 347255 CDS YP_002845408.1 229586907 7815594 complement(825199..825591) 1 NC_012633.1 Putative DNA alkylation repair enzyme 825591 7815594 RAF_ORF0786 Rickettsia africae ESF-5 Putative DNA alkylation repair enzyme YP_002845408.1 825199 R 347255 CDS YP_002845409.1 229586908 7815596 complement(826884..827390) 1 NC_012633.1 Methylated-DNA--protein-cysteine methyltransferase 827390 dat 7815596 dat Rickettsia africae ESF-5 Methylated-DNA--protein-cysteine methyltransferase YP_002845409.1 826884 R 347255 CDS YP_002845410.1 229586909 7815598 complement(829744..830217) 1 NC_012633.1 hypothetical protein 830217 7815598 RAF_ORF0793 Rickettsia africae ESF-5 hypothetical protein YP_002845410.1 829744 R 347255 CDS YP_002845411.1 229586910 7815600 complement(830788..830997) 1 NC_012633.1 hypothetical protein 830997 7815600 RAF_ORF0794 Rickettsia africae ESF-5 hypothetical protein YP_002845411.1 830788 R 347255 CDS YP_002845412.1 229586911 7815601 complement(831323..831565) 1 NC_012633.1 Ankyrin repeat protein 831565 7815601 RAF_ORF0795 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002845412.1 831323 R 347255 CDS YP_002845413.1 229586912 7815602 complement(832626..835346) 1 NC_012633.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 835346 secA 7815602 secA Rickettsia africae ESF-5 preprotein translocase subunit SecA YP_002845413.1 832626 R 347255 CDS YP_002845414.1 229586913 7815603 835562..836410 1 NC_012633.1 Protein export protein prsA precursor 836410 prsA 7815603 prsA Rickettsia africae ESF-5 Protein export protein prsA precursor YP_002845414.1 835562 D 347255 CDS YP_002845415.1 229586914 7815604 complement(836620..837015) 1 NC_012633.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 837015 acpS 7815604 acpS Rickettsia africae ESF-5 4'-phosphopantetheinyl transferase YP_002845415.1 836620 R 347255 CDS YP_002845416.1 229586915 7815605 complement(837016..837399) 1 NC_012633.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 837399 rpoZ 7815605 rpoZ Rickettsia africae ESF-5 DNA-directed RNA polymerase subunit omega YP_002845416.1 837016 R 347255 CDS YP_002845417.1 229586916 7815606 complement(837588..838847) 1 NC_012633.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 838847 murA 7815606 murA Rickettsia africae ESF-5 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002845417.1 837588 R 347255 CDS YP_002845418.1 229586917 7815607 complement(838939..841362) 1 NC_012633.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 841362 gyrB 7815607 gyrB Rickettsia africae ESF-5 DNA gyrase subunit B YP_002845418.1 838939 R 347255 CDS YP_002845419.1 229586918 7815608 841642..842502 1 NC_012633.1 HAD-superfamily hydrolase 842502 7815608 RAF_ORF0802 Rickettsia africae ESF-5 HAD-superfamily hydrolase YP_002845419.1 841642 D 347255 CDS YP_002845420.1 229586919 7815610 843008..844378 1 NC_012633.1 Magnesium transporter 844378 mgtE 7815610 mgtE Rickettsia africae ESF-5 Magnesium transporter YP_002845420.1 843008 D 347255 CDS YP_002845421.1 229586920 7815611 complement(844382..844669) 1 NC_012633.1 hypothetical protein 844669 7815611 RAF_ORF0804 Rickettsia africae ESF-5 hypothetical protein YP_002845421.1 844382 R 347255 CDS YP_002845422.1 229586921 7815612 845228..845497 1 NC_012633.1 Guanosine polyphosphate pyrophosphohydrolase/synthetase 845497 spoT3 7815612 spoT3 Rickettsia africae ESF-5 Guanosine polyphosphate pyrophosphohydrolase/synthetase YP_002845422.1 845228 D 347255 CDS YP_002845423.1 229586922 7815613 complement(845714..846112) 1 NC_012633.1 Proline/betaine transporter 846112 proP9 7815613 proP9 Rickettsia africae ESF-5 Proline/betaine transporter YP_002845423.1 845714 R 347255 CDS YP_002845424.1 229586923 7815616 848009..848623 1 NC_012633.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 848623 yajC 7815616 yajC Rickettsia africae ESF-5 preprotein translocase subunit YajC YP_002845424.1 848009 D 347255 CDS YP_002845425.1 229586924 7815617 848607..850163 1 NC_012633.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 850163 secD 7815617 secD Rickettsia africae ESF-5 preprotein translocase subunit SecD YP_002845425.1 848607 D 347255 CDS YP_002845426.1 229586925 7815618 850408..851028 1 NC_012633.1 Sco2 protein precursor 851028 7815618 RAF_ORF0811 Rickettsia africae ESF-5 Sco2 protein precursor YP_002845426.1 850408 D 347255 CDS YP_002845427.1 229586926 7815619 851021..851152 1 NC_012633.1 hypothetical protein 851152 7815619 RAF_ORF0812 Rickettsia africae ESF-5 hypothetical protein YP_002845427.1 851021 D 347255 CDS YP_002845428.1 229586927 7815620 851130..851516 1 NC_012633.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 851516 ccmE 7815620 ccmE Rickettsia africae ESF-5 cytochrome c-type biogenesis protein CcmE YP_002845428.1 851130 D 347255 CDS YP_002845429.1 229586928 7815621 851642..852163 1 NC_012633.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 852163 ppa 7815621 ppa Rickettsia africae ESF-5 inorganic pyrophosphatase YP_002845429.1 851642 D 347255 CDS YP_002845430.1 229586929 7815622 852374..854041 1 NC_012633.1 Integral membrane protein MviN 854041 mviN 7815622 mviN Rickettsia africae ESF-5 Integral membrane protein MviN YP_002845430.1 852374 D 347255 CDS YP_002845431.1 229586930 7815623 854022..854774 1 NC_012633.1 F pilin acetylation protein TraX 854774 traX 7815623 traX Rickettsia africae ESF-5 F pilin acetylation protein TraX YP_002845431.1 854022 D 347255 CDS YP_002845432.1 229586931 7815624 854848..855450 1 NC_012633.1 hypothetical protein 855450 7815624 RAF_ORF0817 Rickettsia africae ESF-5 hypothetical protein YP_002845432.1 854848 D 347255 CDS YP_002845433.1 229586932 7815625 complement(855658..857799) 1 NC_012633.1 ATP-dependent DNA helicase RecG 857799 recG 7815625 recG Rickettsia africae ESF-5 ATP-dependent DNA helicase RecG YP_002845433.1 855658 R 347255 CDS YP_002845434.1 229586933 7815626 complement(858072..858644) 1 NC_012633.1 hypothetical protein 858644 7815626 RAF_ORF0819 Rickettsia africae ESF-5 hypothetical protein YP_002845434.1 858072 R 347255 CDS YP_002845435.1 229586934 7815627 859213..859854 1 NC_012633.1 Succinyl-CoA:3-ketoacid-coenzyme A transferase 859854 scoA 7815627 scoA Rickettsia africae ESF-5 Succinyl-CoA:3-ketoacid-coenzyme A transferase YP_002845435.1 859213 D 347255 CDS YP_002845436.1 229586935 7815628 859858..860493 1 NC_012633.1 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B 860493 scoB 7815628 scoB Rickettsia africae ESF-5 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B YP_002845436.1 859858 D 347255 CDS YP_002845437.1 229586936 7815630 complement(861131..862633) 1 NC_012633.1 Actin polymerization protein RickA 862633 rickA 7815630 rickA Rickettsia africae ESF-5 Actin polymerization protein RickA YP_002845437.1 861131 R 347255 CDS YP_002845438.1 229586937 7815631 complement(862743..863828) 1 NC_012633.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 863828 mraY 7815631 mraY Rickettsia africae ESF-5 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002845438.1 862743 R 347255 CDS YP_002845439.1 229586938 7815632 complement(864023..865372) 1 NC_012633.1 UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate--D-alanyl-D-alanyl ligase 865372 murF 7815632 murF Rickettsia africae ESF-5 UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate--D-alanyl-D-alanyl ligase YP_002845439.1 864023 R 347255 CDS YP_002845440.1 229586939 7815633 complement(865581..867020) 1 NC_012633.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 867020 murE 7815633 murE Rickettsia africae ESF-5 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002845440.1 865581 R 347255 CDS YP_002845441.1 229586940 7815634 complement(867167..870535) 1 NC_012633.1 transcription-repair coupling factor 870535 mfd 7815634 mfd Rickettsia africae ESF-5 transcription-repair coupling factor YP_002845441.1 867167 R 347255 CDS YP_002845442.1 229586941 7815635 complement(870547..870810) 1 NC_012633.1 hypothetical protein 870810 7815635 RAF_ORF0829 Rickettsia africae ESF-5 hypothetical protein YP_002845442.1 870547 R 347255 CDS YP_002845443.1 229586942 7815636 870972..871343 1 NC_012633.1 Rhodanese-related sulfurtransferase 871343 pspE 7815636 pspE Rickettsia africae ESF-5 Rhodanese-related sulfurtransferase YP_002845443.1 870972 D 347255 CDS YP_002845444.1 229586943 7815637 871344..872735 1 NC_012633.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 872735 dnaA 7815637 dnaA Rickettsia africae ESF-5 chromosomal replication initiation protein YP_002845444.1 871344 D 347255 CDS YP_002845445.1 229586944 7815639 complement(875425..875670) 1 NC_012633.1 hypothetical protein 875670 7815639 RAF_ORF0834 Rickettsia africae ESF-5 hypothetical protein YP_002845445.1 875425 R 347255 CDS YP_002845446.1 229586945 7815640 875866..877338 1 NC_012633.1 Patatin-like phospholipase 877338 pat1 7815640 pat1 Rickettsia africae ESF-5 Patatin-like phospholipase YP_002845446.1 875866 D 347255 CDS YP_002845447.1 229586946 7815643 complement(879671..880768) 1 NC_012633.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 880768 ychF 7815643 ychF Rickettsia africae ESF-5 GTP-dependent nucleic acid-binding protein EngD YP_002845447.1 879671 R 347255 CDS YP_002845448.1 229586947 7815644 complement(880765..880935) 1 NC_012633.1 Acetyltransferase 880935 7815644 RAF_ORF0842 Rickettsia africae ESF-5 Acetyltransferase YP_002845448.1 880765 R 347255 CDS YP_002845449.1 229586948 7815645 complement(881397..881954) 1 NC_012633.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 881954 pth 7815645 pth Rickettsia africae ESF-5 peptidyl-tRNA hydrolase YP_002845449.1 881397 R 347255 CDS YP_002845450.1 229586949 7815646 complement(882277..882888) 1 NC_012633.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 882888 rplY 7815646 rplY Rickettsia africae ESF-5 50S ribosomal protein L25/general stress protein Ctc YP_002845450.1 882277 R 347255 CDS YP_002845451.1 229586950 7815647 complement(883634..884311) 1 NC_012633.1 Organic radical activating enzyme 884311 nrdG 7815647 nrdG Rickettsia africae ESF-5 Organic radical activating enzyme YP_002845451.1 883634 R 347255 CDS YP_002845452.1 229586951 7815648 884415..884684 1 NC_012633.1 50S ribosomal protein L35 884684 rpmI 7815648 rpmI Rickettsia africae ESF-5 50S ribosomal protein L35 YP_002845452.1 884415 D 347255 CDS YP_002845453.1 229586952 7815649 884704..885057 1 NC_012633.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 885057 rplT 7815649 rplT Rickettsia africae ESF-5 50S ribosomal protein L20 YP_002845453.1 884704 D 347255 CDS YP_002845454.1 229586953 7815650 885140..885274 1 NC_012633.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 885274 rpmH 7815650 rpmH Rickettsia africae ESF-5 50S ribosomal protein L34 YP_002845454.1 885140 D 347255 CDS YP_002845455.1 229586954 7815651 885294..885650 1 NC_012633.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 885650 rnpA 7815651 rnpA Rickettsia africae ESF-5 ribonuclease P YP_002845455.1 885294 D 347255 CDS YP_002845456.1 229586955 7815652 complement(886159..888099) 1 NC_012633.1 hypothetical protein 888099 7815652 RAF_ORF0850 Rickettsia africae ESF-5 hypothetical protein YP_002845456.1 886159 R 347255 CDS YP_002845457.1 229586956 7815653 complement(889694..890011) 1 NC_012633.1 hypothetical protein 890011 7815653 RAF_ORF0851 Rickettsia africae ESF-5 hypothetical protein YP_002845457.1 889694 R 347255 CDS YP_002845458.1 229586957 7815654 complement(890229..891188) 1 NC_012633.1 Magnesium and cobalt transport protein CorA 891188 corA 7815654 corA Rickettsia africae ESF-5 Magnesium and cobalt transport protein CorA YP_002845458.1 890229 R 347255 CDS YP_002845459.1 229586958 7815655 complement(891877..892260) 1 NC_012633.1 hypothetical protein 892260 7815655 RAF_ORF0853 Rickettsia africae ESF-5 hypothetical protein YP_002845459.1 891877 R 347255 CDS YP_002845460.1 229586959 7815658 complement(895942..897741) 1 NC_012633.1 Nitrogen regulation protein NtrY 897741 ntrY 7815658 ntrY Rickettsia africae ESF-5 Nitrogen regulation protein NtrY YP_002845460.1 895942 R 347255 CDS YP_002845461.1 229586960 7815256 complement(898108..898308) 1 NC_012633.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 898308 rpsU 7815256 rpsU Rickettsia africae ESF-5 30S ribosomal protein S21 YP_002845461.1 898108 R 347255 CDS YP_002845462.1 229586961 7814857 898333..898998 1 NC_012633.1 hypothetical protein 898998 7814857 RAF_ORF0858 Rickettsia africae ESF-5 hypothetical protein YP_002845462.1 898333 D 347255 CDS YP_002845463.1 229586962 7814858 899989..903267 1 NC_012633.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 903267 ileS 7814858 ileS Rickettsia africae ESF-5 isoleucyl-tRNA synthetase YP_002845463.1 899989 D 347255 CDS YP_002845464.1 229586963 7814859 903731..904012 1 NC_012633.1 Ankyrin repeat protein 904012 7814859 RAF_ORF0860 Rickettsia africae ESF-5 Ankyrin repeat protein YP_002845464.1 903731 D 347255 CDS YP_002845465.1 229586964 7814860 905074..905301 1 NC_012633.1 hypothetical protein 905301 7814860 RAF_ORF0861 Rickettsia africae ESF-5 hypothetical protein YP_002845465.1 905074 D 347255 CDS YP_002845466.1 229586965 7814861 complement(905612..907609) 1 NC_012633.1 Acetyl-CoA carboxylase, biotin carboxylase 907609 accC 7814861 accC Rickettsia africae ESF-5 Acetyl-CoA carboxylase, biotin carboxylase YP_002845466.1 905612 R 347255 CDS YP_002845467.1 229586966 7814862 complement(907707..909251) 1 NC_012633.1 Propionyl-CoA carboxylase beta chain precursor 909251 pccB 7814862 pccB Rickettsia africae ESF-5 Propionyl-CoA carboxylase beta chain precursor YP_002845467.1 907707 R 347255 CDS YP_002845468.1 229586967 7814863 909327..909575 1 NC_012633.1 hypothetical protein 909575 7814863 RAF_ORF0864 Rickettsia africae ESF-5 hypothetical protein YP_002845468.1 909327 D 347255 CDS YP_002845469.1 229586968 7814864 909810..913232 1 NC_012633.1 Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein; acylglycerophosphoethanolamine acyltransferase 913232 aas 7814864 aas Rickettsia africae ESF-5 acylglycerophosphoethanolamine acyltransferase YP_002845469.1 909810 D 347255 CDS YP_002845470.1 229586969 7814865 complement(913499..913705) 1 NC_012633.1 Regulator of competence-specific genes TfoX 913705 tfoX 7814865 tfoX Rickettsia africae ESF-5 Regulator of competence-specific genes TfoX YP_002845470.1 913499 R 347255 CDS YP_002845471.1 229586970 7814866 complement(913702..914463) 1 NC_012633.1 Zinc/manganese ABC transporter permease protein 914463 znuB 7814866 znuB Rickettsia africae ESF-5 Zinc/manganese ABC transporter permease protein YP_002845471.1 913702 R 347255 CDS YP_002845472.1 229586971 7814867 914601..915470 1 NC_012633.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 915470 ubiG 7814867 ubiG Rickettsia africae ESF-5 3-demethylubiquinone-9 3-methyltransferase YP_002845472.1 914601 D 347255 CDS YP_002845473.1 229586972 7814868 915769..917310 1 NC_012633.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 917310 gltX 7814868 gltX Rickettsia africae ESF-5 glutamyl-tRNA synthetase YP_002845473.1 915769 D 347255 CDS YP_002845474.1 229586973 7814869 917307..917843 1 NC_012633.1 hypothetical protein 917843 7814869 RAF_ORF0870 Rickettsia africae ESF-5 hypothetical protein YP_002845474.1 917307 D 347255 CDS YP_002845475.1 229586974 7814870 complement(918802..920445) 1 NC_012633.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 920445 groEL 7814870 groEL Rickettsia africae ESF-5 chaperonin GroEL YP_002845475.1 918802 R 347255 CDS YP_002845476.1 229586975 7814871 complement(920473..920772) 1 NC_012633.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 920772 groES 7814871 groES Rickettsia africae ESF-5 co-chaperonin GroES YP_002845476.1 920473 R 347255 CDS YP_002845477.1 229586976 7814873 complement(922814..923296) 1 NC_012633.1 hypothetical protein 923296 7814873 RAF_ORF0876 Rickettsia africae ESF-5 hypothetical protein YP_002845477.1 922814 R 347255 CDS YP_002845478.1 229586977 7814874 complement(923998..924717) 1 NC_012633.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 924717 rph 7814874 rph Rickettsia africae ESF-5 ribonuclease PH YP_002845478.1 923998 R 347255 CDS YP_002845479.1 229586978 7814875 924941..925477 1 NC_012633.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 925477 grpE 7814875 grpE Rickettsia africae ESF-5 heat shock protein GrpE YP_002845479.1 924941 D 347255 CDS YP_002845480.1 229586979 7814876 925606..926676 1 NC_012633.1 Permease PerM-like protein 926676 perM 7814876 perM Rickettsia africae ESF-5 Permease PerM-like protein YP_002845480.1 925606 D 347255 CDS YP_002845481.1 229586980 7814877 926692..927360 1 NC_012633.1 hypothetical protein 927360 7814877 RAF_ORF0880 Rickettsia africae ESF-5 hypothetical protein YP_002845481.1 926692 D 347255 CDS YP_002845482.1 229586981 7814878 927668..927910 1 NC_012633.1 MFS-type sugar transporter 927910 7814878 RAF_ORF0881 Rickettsia africae ESF-5 MFS-type sugar transporter YP_002845482.1 927668 D 347255 CDS YP_002845483.1 229586982 7814879 complement(928659..928892) 1 NC_012633.1 hypothetical protein 928892 7814879 RAF_ORF0882 Rickettsia africae ESF-5 hypothetical protein YP_002845483.1 928659 R 347255 CDS YP_002845484.1 229586983 7814882 complement(930496..930774) 1 NC_012633.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 930774 rpsT 7814882 rpsT Rickettsia africae ESF-5 30S ribosomal protein S20 YP_002845484.1 930496 R 347255 CDS YP_002845485.1 229586984 7814883 complement(930793..931203) 1 NC_012633.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 931203 rplQ 7814883 rplQ Rickettsia africae ESF-5 50S ribosomal protein L17 YP_002845485.1 930793 R 347255 CDS YP_002845486.1 229586985 7814884 complement(931214..932236) 1 NC_012633.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 932236 rpoA 7814884 rpoA Rickettsia africae ESF-5 DNA-directed RNA polymerase subunit alpha YP_002845486.1 931214 R 347255 CDS YP_002845487.1 229586986 7814885 complement(932255..932638) 1 NC_012633.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 932638 rpsK 7814885 rpsK Rickettsia africae ESF-5 30S ribosomal protein S11 YP_002845487.1 932255 R 347255 CDS YP_002845488.1 229586987 7814886 complement(932663..933040) 1 NC_012633.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 933040 rpsM 7814886 rpsM Rickettsia africae ESF-5 30S ribosomal protein S13 YP_002845488.1 932663 R 347255 CDS YP_002845489.1 229586988 7814887 complement(933099..933737) 1 NC_012633.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 933737 adk 7814887 adk Rickettsia africae ESF-5 adenylate kinase YP_002845489.1 933099 R 347255 CDS YP_002845490.1 229586989 7814888 complement(933753..935054) 1 NC_012633.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 935054 secY 7814888 secY Rickettsia africae ESF-5 preprotein translocase subunit SecY YP_002845490.1 933753 R 347255 CDS YP_002845491.1 229586990 7814889 complement(935058..935519) 1 NC_012633.1 late assembly protein; 50S ribosomal protein L15 935519 rplO 7814889 rplO Rickettsia africae ESF-5 50S ribosomal protein L15 YP_002845491.1 935058 R 347255 CDS YP_002845492.1 229586991 7814890 complement(935533..935724) 1 NC_012633.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 935724 rpmD 7814890 rpmD Rickettsia africae ESF-5 50S ribosomal protein L30 YP_002845492.1 935533 R 347255 CDS YP_002845493.1 229586992 7814891 complement(935748..936278) 1 NC_012633.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 936278 rpsE 7814891 rpsE Rickettsia africae ESF-5 30S ribosomal protein S5 YP_002845493.1 935748 R 347255 CDS YP_002845494.1 229586993 7814892 complement(936296..936652) 1 NC_012633.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 936652 rplR 7814892 rplR Rickettsia africae ESF-5 50S ribosomal protein L18 YP_002845494.1 936296 R 347255 CDS YP_002845495.1 229586994 7814893 complement(936668..937201) 1 NC_012633.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 937201 rplF 7814893 rplF Rickettsia africae ESF-5 50S ribosomal protein L6 YP_002845495.1 936668 R 347255 CDS YP_002845496.1 229586995 7814894 complement(937210..937608) 1 NC_012633.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 937608 rpsH 7814894 rpsH Rickettsia africae ESF-5 30S ribosomal protein S8 YP_002845496.1 937210 R 347255 CDS YP_002845497.1 229586996 7814895 complement(937628..937933) 1 NC_012633.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 937933 rpsN 7814895 rpsN Rickettsia africae ESF-5 30S ribosomal protein S14 YP_002845497.1 937628 R 347255 CDS YP_002845498.1 229586997 7814896 complement(937951..938490) 1 NC_012633.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 938490 rplE 7814896 rplE Rickettsia africae ESF-5 50S ribosomal protein L5 YP_002845498.1 937951 R 347255 CDS YP_002845499.1 229586998 7814897 complement(938490..938819) 1 NC_012633.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 938819 rplX 7814897 rplX Rickettsia africae ESF-5 50S ribosomal protein L24 YP_002845499.1 938490 R 347255 CDS YP_002845500.1 229586999 7814898 complement(938820..939188) 1 NC_012633.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 939188 rplN 7814898 rplN Rickettsia africae ESF-5 50S ribosomal protein L14 YP_002845500.1 938820 R 347255 CDS YP_002845501.1 229587000 7814899 complement(939263..939511) 1 NC_012633.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 939511 rpsQ 7814899 rpsQ Rickettsia africae ESF-5 30S ribosomal protein S17 YP_002845501.1 939263 R 347255 CDS YP_002845502.1 229587001 7814900 complement(939498..939713) 1 NC_012633.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 939713 rpmC 7814900 rpmC Rickettsia africae ESF-5 50S ribosomal protein L29 YP_002845502.1 939498 R 347255 CDS YP_002845503.1 229587002 7814901 complement(939706..940116) 1 NC_012633.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 940116 rplP 7814901 rplP Rickettsia africae ESF-5 50S ribosomal protein L16 YP_002845503.1 939706 R 347255 CDS YP_002845504.1 229587003 7814902 complement(940131..940784) 1 NC_012633.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 940784 rpsC 7814902 rpsC Rickettsia africae ESF-5 30S ribosomal protein S3 YP_002845504.1 940131 R 347255 CDS YP_002845505.1 229587004 7814903 complement(940786..941145) 1 NC_012633.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 941145 rplV 7814903 rplV Rickettsia africae ESF-5 50S ribosomal protein L22 YP_002845505.1 940786 R 347255 CDS YP_002845506.1 229587005 7814904 complement(941154..941432) 1 NC_012633.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 941432 rpsS 7814904 rpsS Rickettsia africae ESF-5 30S ribosomal protein S19 YP_002845506.1 941154 R 347255 CDS YP_002845507.1 229587006 7814905 complement(941457..942278) 1 NC_012633.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 942278 rplB 7814905 rplB Rickettsia africae ESF-5 50S ribosomal protein L2 YP_002845507.1 941457 R 347255 CDS YP_002845508.1 229587007 7814906 complement(942279..942575) 1 NC_012633.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 942575 rplW 7814906 rplW Rickettsia africae ESF-5 50S ribosomal protein L23 YP_002845508.1 942279 R 347255 CDS YP_002845509.1 229587008 7814907 complement(942572..943195) 1 NC_012633.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 943195 rplD 7814907 rplD Rickettsia africae ESF-5 50S ribosomal protein L4 YP_002845509.1 942572 R 347255 CDS YP_002845510.1 229587009 7814908 complement(943306..943953) 1 NC_012633.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 943953 rplC 7814908 rplC Rickettsia africae ESF-5 50S ribosomal protein L3 YP_002845510.1 943306 R 347255 CDS YP_002845511.1 229587010 7814909 complement(943954..944271) 1 NC_012633.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 944271 rpsJ 7814909 rpsJ Rickettsia africae ESF-5 30S ribosomal protein S10 YP_002845511.1 943954 R 347255 CDS YP_002845512.1 229587011 7814910 complement(944513..945697) 1 NC_012633.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 945697 tuf 7814910 tuf Rickettsia africae ESF-5 elongation factor Tu YP_002845512.1 944513 R 347255 CDS YP_002845513.1 229587012 7814913 946274..946996 1 NC_012633.1 tRNA/rRNA methyltransferase 946996 7814913 RAF_ORF0915 Rickettsia africae ESF-5 tRNA/rRNA methyltransferase YP_002845513.1 946274 D 347255 CDS YP_002845514.1 229587013 7814914 947096..947548 1 NC_012633.1 hypothetical protein 947548 7814914 RAF_ORF0916 Rickettsia africae ESF-5 hypothetical protein YP_002845514.1 947096 D 347255 CDS YP_002845515.1 229587014 7814915 947545..948936 1 NC_012633.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 948936 fumC 7814915 fumC Rickettsia africae ESF-5 fumarate hydratase YP_002845515.1 947545 D 347255 CDS YP_002845516.1 229587015 7814916 949033..949281 1 NC_012633.1 Antitoxin of toxin-antitoxin (TA) system Phd 949281 7814916 RAF_ORF0918 Rickettsia africae ESF-5 Antitoxin of toxin-antitoxin (TA) system Phd YP_002845516.1 949033 D 347255 CDS YP_002845517.1 229587016 7814917 949275..949598 1 NC_012633.1 Toxin of toxin-antitoxin (TA) system, containing PIN domain for nucleic acid binding 949598 7814917 RAF_ORF0919 Rickettsia africae ESF-5 Toxin of toxin-antitoxin (TA) system, containing PIN domain for nucleic acid binding YP_002845517.1 949275 D 347255 CDS YP_002845518.1 229587017 7814918 949779..951137 1 NC_012633.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 951137 ftsZ 7814918 ftsZ Rickettsia africae ESF-5 cell division protein FtsZ YP_002845518.1 949779 D 347255 CDS YP_002845519.1 229587018 7814919 951411..952061 1 NC_012633.1 hypothetical protein 952061 7814919 RAF_ORF0921 Rickettsia africae ESF-5 hypothetical protein YP_002845519.1 951411 D 347255 CDS YP_002845520.1 229587019 7814920 952155..952451 1 NC_012633.1 Ecotin precursor 952451 ecoT 7814920 ecoT Rickettsia africae ESF-5 Ecotin precursor YP_002845520.1 952155 D 347255 CDS YP_002845521.1 229587020 7814921 complement(952669..953241) 1 NC_012633.1 NifU-like protein 953241 7814921 RAF_ORF0923 Rickettsia africae ESF-5 NifU-like protein YP_002845521.1 952669 R 347255 CDS YP_002845522.1 229587021 7814922 complement(953589..954653) 1 NC_012633.1 AmpG protein 954653 ampG2 7814922 ampG2 Rickettsia africae ESF-5 AmpG protein YP_002845522.1 953589 R 347255 CDS YP_002845523.1 229587022 7814923 complement(955009..956241) 1 NC_012633.1 ATP-dependent RNA helicase RhlE 956241 rhlE 7814923 rhlE Rickettsia africae ESF-5 ATP-dependent RNA helicase RhlE YP_002845523.1 955009 R 347255 CDS YP_002845524.1 229587023 7814924 complement(956755..956967) 1 NC_012633.1 Cold shock-like protein 956967 cspA 7814924 cspA Rickettsia africae ESF-5 Cold shock-like protein YP_002845524.1 956755 R 347255 CDS YP_002845525.1 229587024 7814925 957083..957211 1 NC_012633.1 hypothetical protein 957211 7814925 RAF_ORF0927 Rickettsia africae ESF-5 hypothetical protein YP_002845525.1 957083 D 347255 CDS YP_002845526.1 229587025 7814927 complement(958368..959273) 1 NC_012633.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 959273 ksgA 7814927 ksgA Rickettsia africae ESF-5 dimethyladenosine transferase YP_002845526.1 958368 R 347255 CDS YP_002845527.1 229587026 7814928 complement(959427..960314) 1 NC_012633.1 hypothetical protein 960314 7814928 RAF_ORF0929 Rickettsia africae ESF-5 hypothetical protein YP_002845527.1 959427 R 347255 CDS YP_002845528.1 229587027 7814929 complement(960470..962272) 1 NC_012633.1 Organic solvent tolerance protein-like protein 962272 ostA 7814929 ostA Rickettsia africae ESF-5 Organic solvent tolerance protein-like protein YP_002845528.1 960470 R 347255 CDS YP_002845529.1 229587028 7814930 962274..962405 1 NC_012633.1 hypothetical protein 962405 7814930 RAF_ORF0931 Rickettsia africae ESF-5 hypothetical protein YP_002845529.1 962274 D 347255 CDS YP_002845530.1 229587029 7814931 962877..964211 1 NC_012633.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 964211 xseA 7814931 xseA Rickettsia africae ESF-5 exodeoxyribonuclease VII large subunit YP_002845530.1 962877 D 347255 CDS YP_002845531.1 229587030 7814932 964217..964534 1 NC_012633.1 hypothetical protein 964534 7814932 RAF_ORF0933 Rickettsia africae ESF-5 hypothetical protein YP_002845531.1 964217 D 347255 CDS YP_002845532.1 229587031 7814933 964888..965670 1 NC_012633.1 Exodeoxyribonuclease III 965670 xth2 7814933 xth2 Rickettsia africae ESF-5 Exodeoxyribonuclease III YP_002845532.1 964888 D 347255 CDS YP_002845533.1 229587032 7814934 965866..966132 1 NC_012633.1 hypothetical protein 966132 7814934 RAF_ORF0935 Rickettsia africae ESF-5 hypothetical protein YP_002845533.1 965866 D 347255 CDS YP_002845534.1 229587033 7814935 966136..967479 1 NC_012633.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 967479 engA 7814935 engA Rickettsia africae ESF-5 GTP-binding protein EngA YP_002845534.1 966136 D 347255 CDS YP_002845535.1 229587034 7814936 complement(967630..968772) 1 NC_012633.1 Putative AAA+ superfamily ATPase 968772 7814936 RAF_ORF0937 Rickettsia africae ESF-5 Putative AAA+ superfamily ATPase YP_002845535.1 967630 R 347255 CDS YP_002845536.1 229587035 7815930 complement(971421..972857) 1 NC_012633.1 2-polyprenylphenol 6-hydroxylase 972857 ubiB 7815930 ubiB Rickettsia africae ESF-5 2-polyprenylphenol 6-hydroxylase YP_002845536.1 971421 R 347255 CDS YP_002845537.1 229587036 7815931 complement(973005..973751) 1 NC_012633.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 973751 ubiE 7815931 ubiE Rickettsia africae ESF-5 ubiquinone/menaquinone biosynthesis methyltransferase YP_002845537.1 973005 R 347255 CDS YP_002845538.1 229587037 7815932 973780..974601 1 NC_012633.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 974601 mutM 7815932 mutM Rickettsia africae ESF-5 formamidopyrimidine-DNA glycosylase YP_002845538.1 973780 D 347255 CDS YP_002845539.1 229587038 7815934 975906..976160 1 NC_012633.1 hypothetical protein 976160 7815934 RAF_ORF0946 Rickettsia africae ESF-5 hypothetical protein YP_002845539.1 975906 D 347255 CDS YP_002845540.1 229587039 7815935 976542..976802 1 NC_012633.1 hypothetical protein 976802 7815935 RAF_ORF0947 Rickettsia africae ESF-5 hypothetical protein YP_002845540.1 976542 D 347255 CDS YP_002845541.1 229587040 7815937 complement(979418..980338) 1 NC_012633.1 deoxyribonuclease TatD 980338 tatD 7815937 tatD Rickettsia africae ESF-5 deoxyribonuclease TatD YP_002845541.1 979418 R 347255 CDS YP_002845542.1 229587041 7815938 complement(980391..981917) 1 NC_012633.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 981917 metG 7815938 metG Rickettsia africae ESF-5 methionyl-tRNA synthetase YP_002845542.1 980391 R 347255 CDS YP_002845543.1 229587042 7815939 complement(981914..982525) 1 NC_012633.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 982525 tmk 7815939 tmk Rickettsia africae ESF-5 thymidylate kinase YP_002845543.1 981914 R 347255 CDS YP_002845544.1 229587043 7815940 982784..984172 1 NC_012633.1 Proline/betaine transporter 984172 proP4 7815940 proP4 Rickettsia africae ESF-5 Proline/betaine transporter YP_002845544.1 982784 D 347255 CDS YP_002845545.1 229587044 7815941 complement(984197..985045) 1 NC_012633.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 985045 ubiA 7815941 ubiA Rickettsia africae ESF-5 4-hydroxybenzoate polyprenyltransferase YP_002845545.1 984197 R 347255 CDS YP_002845546.1 229587045 7815943 986173..988611 1 NC_012633.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 988611 valS 7815943 valS Rickettsia africae ESF-5 valyl-tRNA synthetase YP_002845546.1 986173 D 347255 CDS YP_002845547.1 229587046 7815944 988765..989334 1 NC_012633.1 LPS biosynthesis protein 989334 7815944 RAF_ORF0958 Rickettsia africae ESF-5 LPS biosynthesis protein YP_002845547.1 988765 D 347255 CDS YP_002845548.1 229587047 7815945 989424..990224 1 NC_012633.1 LPS biosynthesis protein 990224 7815945 RAF_ORF0959 Rickettsia africae ESF-5 LPS biosynthesis protein YP_002845548.1 989424 D 347255 CDS YP_002845549.1 229587048 7815947 991973..993259 1 NC_012633.1 RmuC family protein 993259 7815947 RAF_ORF0962 Rickettsia africae ESF-5 RmuC family protein YP_002845549.1 991973 D 347255 CDS YP_002845550.1 229587049 7815949 994541..994858 1 NC_012633.1 LPS biosynthesis glycosyltransferase 994858 7815949 RAF_ORF0965 Rickettsia africae ESF-5 LPS biosynthesis glycosyltransferase YP_002845550.1 994541 D 347255 CDS YP_002845551.1 229587050 7815952 998603..998911 1 NC_012633.1 Putative integral membrane protein 998911 7815952 RAF_ORF0973 Rickettsia africae ESF-5 Putative integral membrane protein YP_002845551.1 998603 D 347255 CDS YP_002845552.1 229587051 7815953 complement(999150..1000427) 1 NC_012633.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1000427 clpX 7815953 clpX Rickettsia africae ESF-5 ATP-dependent protease ATP-binding subunit ClpX YP_002845552.1 999150 R 347255 CDS YP_002845553.1 229587052 7815954 complement(1000465..1001016) 1 NC_012633.1 Ribosomal-protein-alanine acetyltransferase 1001016 rimJ 7815954 rimJ Rickettsia africae ESF-5 Ribosomal-protein-alanine acetyltransferase YP_002845553.1 1000465 R 347255 CDS YP_002845554.1 229587053 7815955 complement(1001176..1001862) 1 NC_012633.1 Trans-regulatory protein ExsB 1001862 exsB 7815955 exsB Rickettsia africae ESF-5 Trans-regulatory protein ExsB YP_002845554.1 1001176 R 347255 CDS YP_002845555.1 229587054 7815956 complement(1001859..1002209) 1 NC_012633.1 HicB-like protein 1002209 7815956 RAF_ORF0977 Rickettsia africae ESF-5 HicB-like protein YP_002845555.1 1001859 R 347255 CDS YP_002845556.1 229587055 7815958 1002825..1004555 1 NC_012633.1 Multidrug resistance protein 1004555 msbA2 7815958 msbA2 Rickettsia africae ESF-5 Multidrug resistance protein YP_002845556.1 1002825 D 347255 CDS YP_002845557.1 229587056 7815959 1004858..1005106 1 NC_012633.1 hypothetical protein 1005106 7815959 RAF_ORF0979 Rickettsia africae ESF-5 hypothetical protein YP_002845557.1 1004858 D 347255 CDS YP_002845558.1 229587057 7815960 1005773..1006945 1 NC_012633.1 MFS-type bicyclomycin resistance protein 1006945 bcr2 7815960 bcr2 Rickettsia africae ESF-5 MFS-type bicyclomycin resistance protein YP_002845558.1 1005773 D 347255 CDS YP_002845559.1 229587058 7815961 1007127..1008377 1 NC_012633.1 Lipoprotein releasing system, transmembrane protein, LolC/E family protein 1008377 7815961 RAF_ORF0981 Rickettsia africae ESF-5 Lipoprotein releasing system, transmembrane protein, LolC/E family protein YP_002845559.1 1007127 D 347255 CDS YP_002845560.1 229587059 7815962 1008370..1009035 1 NC_012633.1 Lipoprotein releasing system ATP-binding protein LolD 1009035 lolD 7815962 lolD Rickettsia africae ESF-5 Lipoprotein releasing system ATP-binding protein LolD YP_002845560.1 1008370 D 347255 CDS YP_002845561.1 229587060 7815963 1009254..1011155 1 NC_012633.1 hypothetical protein 1011155 7815963 RAF_ORF0983 Rickettsia africae ESF-5 hypothetical protein YP_002845561.1 1009254 D 347255 CDS YP_002845562.1 229587061 7815964 1011230..1012504 1 NC_012633.1 Hemolysin-like protein 1012504 7815964 RAF_ORF0984 Rickettsia africae ESF-5 Hemolysin-like protein YP_002845562.1 1011230 D 347255 CDS YP_002845563.1 229587062 7815965 1012497..1014485 1 NC_012633.1 Cytochrome c-type biogenesis protein ccmF 1014485 ccmF 7815965 ccmF Rickettsia africae ESF-5 Cytochrome c-type biogenesis protein ccmF YP_002845563.1 1012497 D 347255 CDS YP_002845564.1 229587063 7815967 complement(1017088..1022052) 1 NC_012633.1 outer membrane protein OmpB 1022052 ompB 7815967 ompB Rickettsia africae ESF-5 outer membrane protein OmpB YP_002845564.1 1017088 R 347255 CDS YP_002845565.1 229587064 7815968 complement(1022444..1023049) 1 NC_012633.1 Guanosine polyphosphate pyrophosphohydrolase/synthetase 1023049 spoT11 7815968 spoT11 Rickettsia africae ESF-5 Guanosine polyphosphate pyrophosphohydrolase/synthetase YP_002845565.1 1022444 R 347255 CDS YP_002845566.1 229587065 7815969 complement(1023414..1024397) 1 NC_012633.1 Beta-glucosidase 1024397 7815969 RAF_ORF0992 Rickettsia africae ESF-5 Beta-glucosidase YP_002845566.1 1023414 R 347255 CDS YP_002845567.1 229587066 7815970 complement(1024401..1024724) 1 NC_012633.1 hypothetical protein 1024724 7815970 RAF_ORF0993 Rickettsia africae ESF-5 hypothetical protein YP_002845567.1 1024401 R 347255 CDS YP_002845568.1 229587067 7815971 complement(1024913..1025200) 1 NC_012633.1 Integration host factor alpha-subunit 1025200 himA 7815971 himA Rickettsia africae ESF-5 Integration host factor alpha-subunit YP_002845568.1 1024913 R 347255 CDS YP_002845569.1 229587068 7815972 complement(1025348..1025815) 1 NC_012633.1 hypothetical protein 1025815 7815972 RAF_ORF0995 Rickettsia africae ESF-5 hypothetical protein YP_002845569.1 1025348 R 347255 CDS YP_002845570.1 229587069 7815973 1026325..1026795 1 NC_012633.1 Bacterioferritin comigratory protein 1026795 bcp 7815973 bcp Rickettsia africae ESF-5 Bacterioferritin comigratory protein YP_002845570.1 1026325 D 347255 CDS YP_002845571.1 229587070 7815974 complement(1026915..1027787) 1 NC_012633.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1027787 htrB 7815974 htrB Rickettsia africae ESF-5 lipid A biosynthesis lauroyl acyltransferase YP_002845571.1 1026915 R 347255 CDS YP_002845572.1 229587071 7815975 complement(1027762..1028727) 1 NC_012633.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1028727 lpxK 7815975 lpxK Rickettsia africae ESF-5 tetraacyldisaccharide 4'-kinase YP_002845572.1 1027762 R 347255 CDS YP_002845573.1 229587072 7815976 complement(1028731..1029585) 1 NC_012633.1 Periplasmic protein 1029585 7815976 RAF_ORF0999 Rickettsia africae ESF-5 Periplasmic protein YP_002845573.1 1028731 R 347255 CDS YP_002845574.1 229587073 7815978 complement(1030670..1030978) 1 NC_012633.1 Putative virulence protein 1030978 7815978 RAF_ORF1002 Rickettsia africae ESF-5 Putative virulence protein YP_002845574.1 1030670 R 347255 CDS YP_002845575.1 229587074 7815979 complement(1031092..1033161) 1 NC_012633.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1033161 ligA 7815979 ligA Rickettsia africae ESF-5 NAD-dependent DNA ligase LigA YP_002845575.1 1031092 R 347255 CDS YP_002845576.1 229587075 7815980 complement(1033263..1033400) 1 NC_012633.1 hypothetical protein 1033400 7815980 RAF_ORF1004 Rickettsia africae ESF-5 hypothetical protein YP_002845576.1 1033263 R 347255 CDS YP_002845577.1 229587076 7815981 complement(1033448..1034533) 1 NC_012633.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1034533 tgt 7815981 tgt Rickettsia africae ESF-5 queuine tRNA-ribosyltransferase YP_002845577.1 1033448 R 347255 CDS YP_002845578.1 229587077 7815984 1037491..1038045 1 NC_012633.1 hypothetical protein 1038045 7815984 RAF_ORF1011 Rickettsia africae ESF-5 hypothetical protein YP_002845578.1 1037491 D 347255 CDS YP_002845579.1 229587078 7815985 complement(1038400..1038528) 1 NC_012633.1 hypothetical protein 1038528 7815985 RAF_ORF1012 Rickettsia africae ESF-5 hypothetical protein YP_002845579.1 1038400 R 347255 CDS YP_002845580.1 229587079 7815986 complement(1038699..1038839) 1 NC_012633.1 hypothetical protein 1038839 7815986 RAF_ORF1013 Rickettsia africae ESF-5 hypothetical protein YP_002845580.1 1038699 R 347255 CDS YP_002845581.1 229587080 7815987 complement(1039147..1039596) 1 NC_012633.1 ABC transporter substrate-binding protein 1039596 7815987 RAF_ORF1014 Rickettsia africae ESF-5 ABC transporter substrate-binding protein YP_002845581.1 1039147 R 347255 CDS YP_002845582.1 229587081 7815988 complement(1039621..1039920) 1 NC_012633.1 hypothetical protein 1039920 7815988 RAF_ORF1015 Rickettsia africae ESF-5 hypothetical protein YP_002845582.1 1039621 R 347255 CDS YP_002845583.1 229587082 7815989 complement(1039908..1040375) 1 NC_012633.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1040375 rnhA 7815989 rnhA Rickettsia africae ESF-5 ribonuclease H YP_002845583.1 1039908 R 347255 CDS YP_002845584.1 229587083 7815990 complement(1040375..1040851) 1 NC_012633.1 hypothetical protein 1040851 7815990 RAF_ORF1017 Rickettsia africae ESF-5 hypothetical protein YP_002845584.1 1040375 R 347255 CDS YP_002845585.1 229587084 7815992 1041631..1042443 1 NC_012633.1 hypothetical protein 1042443 7815992 RAF_ORF1018 Rickettsia africae ESF-5 hypothetical protein YP_002845585.1 1041631 D 347255 CDS YP_002845586.1 229587085 7815993 1042437..1043012 1 NC_012633.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1043012 coaE 7815993 coaE Rickettsia africae ESF-5 dephospho-CoA kinase YP_002845586.1 1042437 D 347255 CDS YP_002845587.1 229587086 7815994 1043000..1043689 1 NC_012633.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1043689 dnaQ 7815994 dnaQ Rickettsia africae ESF-5 DNA polymerase III subunit epsilon YP_002845587.1 1043000 D 347255 CDS YP_002845588.1 229587087 7815995 1043816..1044538 1 NC_012633.1 Surfeit locus protein 1 1044538 surf1 7815995 surf1 Rickettsia africae ESF-5 Surfeit locus protein 1 YP_002845588.1 1043816 D 347255 CDS YP_002845589.1 229587088 7815996 1044594..1047062 1 NC_012633.1 ATP-dependent helicase 1047062 7815996 RAF_ORF1022 Rickettsia africae ESF-5 ATP-dependent helicase YP_002845589.1 1044594 D 347255 CDS YP_002845590.1 229587089 7815997 complement(1047543..1048112) 1 NC_012633.1 hypothetical protein 1048112 7815997 RAF_ORF1023 Rickettsia africae ESF-5 hypothetical protein YP_002845590.1 1047543 R 347255 CDS YP_002845591.1 229587090 7815998 1048321..1049265 1 NC_012633.1 Malonyl CoA-acyl carrier protein transacylase 1049265 fabD 7815998 fabD Rickettsia africae ESF-5 Malonyl CoA-acyl carrier protein transacylase YP_002845591.1 1048321 D 347255 CDS YP_002845592.1 229587091 7815999 1050151..1050465 1 NC_012633.1 hypothetical protein 1050465 7815999 RAF_ORF1025 Rickettsia africae ESF-5 hypothetical protein YP_002845592.1 1050151 D 347255 CDS YP_002845593.1 229587092 7816001 complement(1050998..1051363) 1 NC_012633.1 hypothetical protein 1051363 7816001 RAF_ORF1026 Rickettsia africae ESF-5 hypothetical protein YP_002845593.1 1050998 R 347255 CDS YP_002845594.1 229587093 7816003 complement(1058209..1059360) 1 NC_012633.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1059360 paaJ 7816003 paaJ Rickettsia africae ESF-5 acetyl-CoA acetyltransferase YP_002845594.1 1058209 R 347255 CDS YP_002845595.1 229587094 7816005 1060635..1062134 1 NC_012633.1 ATP/ADP translocase 1062134 tlc5 7816005 tlc5 Rickettsia africae ESF-5 ATP/ADP translocase YP_002845595.1 1060635 D 347255 CDS YP_002845596.1 229587095 7816006 complement(1062657..1063031) 1 NC_012633.1 (Di)nucleoside polyphosphate hydrolase-like protein 1063031 7816006 RAF_ORF1038 Rickettsia africae ESF-5 (Di)nucleoside polyphosphate hydrolase-like protein YP_002845596.1 1062657 R 347255 CDS YP_002845597.1 229587096 7816007 complement(1063703..1064602) 1 NC_012633.1 Hemolysin C 1064602 tlyC 7816007 tlyC Rickettsia africae ESF-5 Hemolysin C YP_002845597.1 1063703 R 347255 CDS YP_002845598.1 229587097 7816008 complement(1064619..1065122) 1 NC_012633.1 putative metalloprotease 1065122 7816008 RAF_ORF1040 Rickettsia africae ESF-5 putative metalloprotease YP_002845598.1 1064619 R 347255 CDS YP_002845599.1 229587098 7816009 complement(1065149..1065352) 1 NC_012633.1 PemK-like growth inhibitor 1065352 7816009 RAF_ORF1041 Rickettsia africae ESF-5 PemK-like growth inhibitor YP_002845599.1 1065149 R 347255 CDS YP_002845600.1 229587099 7815740 complement(1065441..1065671) 1 NC_012633.1 hypothetical protein 1065671 7815740 RAF_ORF1042 Rickettsia africae ESF-5 hypothetical protein YP_002845600.1 1065441 R 347255 CDS YP_002845601.1 229587100 7815741 complement(1065804..1066694) 1 NC_012633.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1066694 lipA 7815741 lipA Rickettsia africae ESF-5 lipoyl synthase YP_002845601.1 1065804 R 347255 CDS YP_002845602.1 229587101 7815742 complement(1066687..1067949) 1 NC_012633.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1067949 glyA 7815742 glyA Rickettsia africae ESF-5 serine hydroxymethyltransferase YP_002845602.1 1066687 R 347255 CDS YP_002845603.1 229587102 7815743 complement(1068064..1068714) 1 NC_012633.1 Serine esterase 1068714 7815743 RAF_ORF1045 Rickettsia africae ESF-5 Serine esterase YP_002845603.1 1068064 R 347255 CDS YP_002845604.1 229587103 7815744 complement(1068870..1069298) 1 NC_012633.1 Glutaredoxin-like protein grla 1069298 grxC2 7815744 grxC2 Rickettsia africae ESF-5 Glutaredoxin-like protein grla YP_002845604.1 1068870 R 347255 CDS YP_002845605.1 229587104 7815745 1069243..1069875 1 NC_012633.1 Endonuclease III 1069875 nth 7815745 nth Rickettsia africae ESF-5 Endonuclease III YP_002845605.1 1069243 D 347255 CDS YP_002845606.1 229587105 7815747 1071463..1071657 1 NC_012633.1 hypothetical protein 1071657 7815747 RAF_ORF1050 Rickettsia africae ESF-5 hypothetical protein YP_002845606.1 1071463 D 347255 CDS YP_002845607.1 229587106 7815749 complement(1072684..1073529) 1 NC_012633.1 Putative methyltransferase 1073529 7815749 RAF_ORF1053 Rickettsia africae ESF-5 Putative methyltransferase YP_002845607.1 1072684 R 347255 CDS YP_002845608.1 229587107 7815750 1073554..1074672 1 NC_012633.1 ABC transporter substrate-binding protein 1074672 7815750 RAF_ORF1054 Rickettsia africae ESF-5 ABC transporter substrate-binding protein YP_002845608.1 1073554 D 347255 CDS YP_002845609.1 229587108 7815751 complement(1074908..1075069) 1 NC_012633.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 1075069 tatA 7815751 tatA Rickettsia africae ESF-5 twin arginine translocase protein A YP_002845609.1 1074908 R 347255 CDS YP_002845610.1 229587109 7815752 1075150..1075749 1 NC_012633.1 phosphatidylglycerophosphatase A 1075749 pgpA 7815752 pgpA Rickettsia africae ESF-5 phosphatidylglycerophosphatase A YP_002845610.1 1075150 D 347255 CDS YP_002845611.1 229587110 7815753 1075838..1076155 1 NC_012633.1 50S ribosomal protein L21 1076155 rplU 7815753 rplU Rickettsia africae ESF-5 50S ribosomal protein L21 YP_002845611.1 1075838 D 347255 CDS YP_002845612.1 229587111 7815754 1076180..1076440 1 NC_012633.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1076440 rpmA 7815754 rpmA Rickettsia africae ESF-5 50S ribosomal protein L27 YP_002845612.1 1076180 D 347255 CDS YP_002845613.1 229587112 7815755 1076721..1077926 1 NC_012633.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1077926 lysC 7815755 lysC Rickettsia africae ESF-5 aspartate kinase YP_002845613.1 1076721 D 347255 CDS YP_002845614.1 229587113 7815756 1078213..1078707 1 NC_012633.1 hypothetical protein 1078707 7815756 RAF_ORF1060 Rickettsia africae ESF-5 hypothetical protein YP_002845614.1 1078213 D 347255 CDS YP_002845615.1 229587114 7815759 complement(1080417..1081658) 1 NC_012633.1 Proline/betaine transporter 1081658 proP5 7815759 proP5 Rickettsia africae ESF-5 Proline/betaine transporter YP_002845615.1 1080417 R 347255 CDS YP_002845616.1 229587115 7815760 complement(1081886..1082008) 1 NC_012633.1 hypothetical protein 1082008 7815760 RAF_ORF1066 Rickettsia africae ESF-5 hypothetical protein YP_002845616.1 1081886 R 347255 CDS YP_002845617.1 229587116 7815761 complement(1081986..1082303) 1 NC_012633.1 hypothetical protein 1082303 7815761 RAF_ORF1067 Rickettsia africae ESF-5 hypothetical protein YP_002845617.1 1081986 R 347255 CDS YP_002845618.1 229587117 7815762 complement(1082306..1082653) 1 NC_012633.1 hypothetical protein 1082653 7815762 RAF_ORF1068 Rickettsia africae ESF-5 hypothetical protein YP_002845618.1 1082306 R 347255 CDS YP_002845619.1 229587118 7815763 complement(1082660..1083013) 1 NC_012633.1 hypothetical protein 1083013 7815763 RAF_ORF1069 Rickettsia africae ESF-5 hypothetical protein YP_002845619.1 1082660 R 347255 CDS YP_002845620.1 229587119 7815764 complement(1083017..1087768) 1 NC_012633.1 NAD-specific glutamate dehydrogenase 1087768 7815764 RAF_ORF1070 Rickettsia africae ESF-5 NAD-specific glutamate dehydrogenase YP_002845620.1 1083017 R 347255 CDS YP_002845621.1 229587120 7815765 1087853..1089190 1 NC_012633.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1089190 trmE 7815765 trmE Rickettsia africae ESF-5 tRNA modification GTPase TrmE YP_002845621.1 1087853 D 347255 CDS YP_002845622.1 229587121 7815766 1089576..1090877 1 NC_012633.1 hypothetical protein 1090877 7815766 RAF_ORF1072 Rickettsia africae ESF-5 hypothetical protein YP_002845622.1 1089576 D 347255 CDS YP_002845623.1 229587122 7815769 1093360..1094391 1 NC_012633.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1094391 recA 7815769 recA Rickettsia africae ESF-5 recombinase A YP_002845623.1 1093360 D 347255 CDS YP_002845624.1 229587123 7815770 1094384..1095109 1 NC_012633.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1095109 fabG 7815770 fabG Rickettsia africae ESF-5 3-ketoacyl-ACP reductase YP_002845624.1 1094384 D 347255 CDS YP_002845625.1 229587124 7815771 1095273..1095533 1 NC_012633.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1095533 acpP 7815771 acpP Rickettsia africae ESF-5 acyl carrier protein YP_002845625.1 1095273 D 347255 CDS YP_002845626.1 229587125 7815772 1095566..1096852 1 NC_012633.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1096852 fabF 7815772 fabF Rickettsia africae ESF-5 3-oxoacyl-(acyl carrier protein) synthase II YP_002845626.1 1095566 D 347255 CDS YP_002845627.1 229587126 7815773 1097134..1098915 1 NC_012633.1 ABC transporter ATP-binding protein 1098915 uup 7815773 uup Rickettsia africae ESF-5 ABC transporter ATP-binding protein YP_002845627.1 1097134 D 347255 CDS YP_002845628.1 229587127 7815774 1098983..1100062 1 NC_012633.1 hypothetical protein 1100062 7815774 RAF_ORF1082 Rickettsia africae ESF-5 hypothetical protein YP_002845628.1 1098983 D 347255 CDS YP_002845629.1 229587128 7815776 complement(1101496..1102185) 1 NC_012633.1 guanylate kinase 1102185 gmk 7815776 gmk Rickettsia africae ESF-5 guanylate kinase YP_002845629.1 1101496 R 347255 CDS YP_002845630.1 229587129 7815777 complement(1102326..1102655) 1 NC_012633.1 hypothetical protein 1102655 7815777 RAF_ORF1087 Rickettsia africae ESF-5 hypothetical protein YP_002845630.1 1102326 R 347255 CDS YP_002845631.1 229587130 7815778 complement(1102910..1103749) 1 NC_012633.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1103749 mreC 7815778 mreC Rickettsia africae ESF-5 rod shape-determining protein MreC YP_002845631.1 1102910 R 347255 CDS YP_002845632.1 229587131 7815779 complement(1103752..1104792) 1 NC_012633.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1104792 mreB 7815779 mreB Rickettsia africae ESF-5 rod shape-determining protein MreB YP_002845632.1 1103752 R 347255 CDS YP_002845633.1 229587132 7815780 complement(1105003..1106091) 1 NC_012633.1 Putative permease 1106091 7815780 RAF_ORF1090 Rickettsia africae ESF-5 Putative permease YP_002845633.1 1105003 R 347255 CDS YP_002845634.1 229587133 7815782 complement(1106519..1106986) 1 NC_012633.1 Peptidoglycan-associated lipoprotein precursor 1106986 pal 7815782 pal Rickettsia africae ESF-5 Peptidoglycan-associated lipoprotein precursor YP_002845634.1 1106519 R 347255 CDS YP_002845635.1 229587134 7815783 1107202..1107444 1 NC_012633.1 hypothetical protein 1107444 7815783 RAF_ORF1092 Rickettsia africae ESF-5 hypothetical protein YP_002845635.1 1107202 D 347255 CDS YP_002845636.1 229587135 7815784 complement(1107459..1108415) 1 NC_012633.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1108415 fabH 7815784 fabH Rickettsia africae ESF-5 3-oxoacyl-ACP synthase YP_002845636.1 1107459 R 347255 CDS YP_002845637.1 229587136 7815785 complement(1108423..1108623) 1 NC_012633.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1108623 rpmF 7815785 rpmF Rickettsia africae ESF-5 50S ribosomal protein L32 YP_002845637.1 1108423 R 347255 CDS YP_002845638.1 229587137 7815786 1108719..1109192 1 NC_012633.1 tmRNA-binding protein 1109192 smpA 7815786 smpA Rickettsia africae ESF-5 tmRNA-binding protein YP_002845638.1 1108719 D 347255 CDS YP_002845639.1 229587138 7815787 1109396..1110307 1 NC_012633.1 Signal recognition particle-docking protein FtsY 1110307 ftsY 7815787 ftsY Rickettsia africae ESF-5 Signal recognition particle-docking protein FtsY YP_002845639.1 1109396 D 347255 CDS YP_002845640.1 229587139 7815788 1110473..1113100 1 NC_012633.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1113100 polA 7815788 polA Rickettsia africae ESF-5 DNA polymerase I YP_002845640.1 1110473 D 347255 CDS YP_002845641.1 229587140 7815791 complement(1115704..1119249) 1 NC_012633.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1119249 dnaE 7815791 dnaE Rickettsia africae ESF-5 DNA polymerase III subunit alpha YP_002845641.1 1115704 R 347255 CDS YP_002845642.1 229587141 7815792 complement(1119366..1120664) 1 NC_012633.1 UDP-glucose 6-dehydrogenase 1120664 udg 7815792 udg Rickettsia africae ESF-5 UDP-glucose 6-dehydrogenase YP_002845642.1 1119366 R 347255 CDS YP_002845643.1 229587142 7815793 1120913..1123423 1 NC_012633.1 hypothetical protein 1123423 7815793 RAF_ORF1105 Rickettsia africae ESF-5 hypothetical protein YP_002845643.1 1120913 D 347255 CDS YP_002845644.1 229587143 7815794 1123450..1125096 1 NC_012633.1 AmpG protein 1125096 ampG3 7815794 ampG3 Rickettsia africae ESF-5 AmpG protein YP_002845644.1 1123450 D 347255 CDS YP_002845645.1 229587144 7815795 1125163..1125918 1 NC_012633.1 Sec-independent protein translocase protein TatC 1125918 tatC 7815795 tatC Rickettsia africae ESF-5 Sec-independent protein translocase protein TatC YP_002845645.1 1125163 D 347255 CDS YP_002845646.1 229587145 7815796 1125896..1127173 1 NC_012633.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1127173 serS 7815796 serS Rickettsia africae ESF-5 seryl-tRNA synthetase YP_002845646.1 1125896 D 347255 CDS YP_002845647.1 229587146 7815797 1127518..1129950 1 NC_012633.1 VirB4 1129950 virB4-2 7815797 virB4-2 Rickettsia africae ESF-5 VirB4 YP_002845647.1 1127518 D 347255 CDS YP_002845648.1 229587147 7815798 1130086..1133574 1 NC_012633.1 hypothetical protein 1133574 7815798 RAF_ORF1110 Rickettsia africae ESF-5 hypothetical protein YP_002845648.1 1130086 D 347255 CDS YP_002845649.1 229587148 7815799 1133579..1134484 1 NC_012633.1 Tellurium resistance protein TerC 1134484 terC 7815799 terC Rickettsia africae ESF-5 Tellurium resistance protein TerC YP_002845649.1 1133579 D 347255 CDS YP_002845650.1 229587149 7815800 1134528..1135241 1 NC_012633.1 hypothetical protein 1135241 7815800 RAF_ORF1112 Rickettsia africae ESF-5 hypothetical protein YP_002845650.1 1134528 D 347255 CDS YP_002845651.1 229587150 7815801 1135327..1136991 1 NC_012633.1 Putative methyltransferase 1136991 7815801 RAF_ORF1113 Rickettsia africae ESF-5 Putative methyltransferase YP_002845651.1 1135327 D 347255 CDS YP_002845652.1 229587151 7815802 1136997..1137755 1 NC_012633.1 Putative transcriptional regulator 1137755 7815802 RAF_ORF1114 Rickettsia africae ESF-5 Putative transcriptional regulator YP_002845652.1 1136997 D 347255 CDS YP_002845653.1 229587152 7815803 1137788..1138405 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1138405 nuoJ 7815803 nuoJ Rickettsia africae ESF-5 NADH dehydrogenase subunit J YP_002845653.1 1137788 D 347255 CDS YP_002845654.1 229587153 7815804 1138380..1138712 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1138712 nuoK 7815804 nuoK Rickettsia africae ESF-5 NADH dehydrogenase subunit K YP_002845654.1 1138380 D 347255 CDS YP_002845655.1 229587154 7815805 1138703..1140685 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1140685 nuoL1 7815805 nuoL1 Rickettsia africae ESF-5 NADH dehydrogenase subunit L YP_002845655.1 1138703 D 347255 CDS YP_002845656.1 229587155 7815806 1140839..1142320 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1142320 nuoM 7815806 nuoM Rickettsia africae ESF-5 NADH dehydrogenase subunit M YP_002845656.1 1140839 D 347255 CDS YP_002845657.1 229587156 7815807 1142650..1143309 1 NC_012633.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1143309 ccmA 7815807 ccmA Rickettsia africae ESF-5 cytochrome c biogenesis protein CcmA YP_002845657.1 1142650 D 347255 CDS YP_002845658.1 229587157 7815808 complement(1143788..1144267) 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1144267 nuoI 7815808 nuoI Rickettsia africae ESF-5 NADH dehydrogenase subunit I YP_002845658.1 1143788 R 347255 CDS YP_002845659.1 229587158 7815809 complement(1144454..1145473) 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1145473 nuoH 7815809 nuoH Rickettsia africae ESF-5 NADH dehydrogenase subunit H YP_002845659.1 1144454 R 347255 CDS YP_002845660.1 229587159 7815810 complement(1145595..1147610) 1 NC_012633.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 1147610 nuoG 7815810 nuoG Rickettsia africae ESF-5 NADH dehydrogenase subunit G YP_002845660.1 1145595 R 347255 CDS YP_002845661.1 229587160 7815811 complement(1147613..1147969) 1 NC_012633.1 hypothetical protein 1147969 7815811 RAF_ORF1123 Rickettsia africae ESF-5 hypothetical protein YP_002845661.1 1147613 R 347255 CDS YP_002845662.1 229587161 7815812 complement(1148138..1150774) 1 NC_012633.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1150774 acnA 7815812 acnA Rickettsia africae ESF-5 aconitate hydratase YP_002845662.1 1148138 R 347255 CDS YP_002845663.1 229587162 7815813 complement(1150956..1151294) 1 NC_012633.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1151294 atpC 7815813 atpC Rickettsia africae ESF-5 F0F1 ATP synthase subunit epsilon YP_002845663.1 1150956 R 347255 CDS YP_002845664.1 229587163 7815814 complement(1151352..1152773) 1 NC_012633.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1152773 atpD 7815814 atpD Rickettsia africae ESF-5 F0F1 ATP synthase subunit beta YP_002845664.1 1151352 R 347255 CDS YP_002845665.1 229587164 7815815 complement(1152946..1153917) 1 NC_012633.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1153917 atpG 7815815 atpG Rickettsia africae ESF-5 F0F1 ATP synthase subunit gamma YP_002845665.1 1152946 R 347255 CDS YP_002845666.1 229587165 7815816 complement(1154050..1155651) 1 NC_012633.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1155651 atpA 7815816 atpA Rickettsia africae ESF-5 F0F1 ATP synthase subunit alpha YP_002845666.1 1154050 R 347255 CDS YP_002845667.1 229587166 7815817 complement(1155748..1156302) 1 NC_012633.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1156302 atpH 7815817 atpH Rickettsia africae ESF-5 F0F1 ATP synthase subunit delta YP_002845667.1 1155748 R 347255 CDS YP_002845668.1 229587167 7815818 complement(1156464..1157843) 1 NC_012633.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1157843 lpdA1 7815818 lpdA1 Rickettsia africae ESF-5 dihydrolipoamide dehydrogenase YP_002845668.1 1156464 R 347255 CDS YP_002845669.1 229587168 7815819 complement(1157994..1158422) 1 NC_012633.1 Strees induced DNA-binding Dps family protein 1158422 7815819 RAF_ORF1131 Rickettsia africae ESF-5 Strees induced DNA-binding Dps family protein YP_002845669.1 1157994 R 347255 CDS YP_002845670.1 229587169 7815419 complement(1160714..1163086) 1 NC_012633.1 Penicillin-binding protein 1A 1163086 mrcA 7815419 mrcA Rickettsia africae ESF-5 Penicillin-binding protein 1A YP_002845670.1 1160714 R 347255 CDS YP_002845671.1 229587170 7815420 complement(1163090..1164427) 1 NC_012633.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1164427 miaB 7815420 miaB Rickettsia africae ESF-5 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002845671.1 1163090 R 347255 CDS YP_002845672.1 229587171 7815422 complement(1166090..1166443) 1 NC_012633.1 hypothetical protein 1166443 7815422 RAF_ORF1140 Rickettsia africae ESF-5 hypothetical protein YP_002845672.1 1166090 R 347255 CDS YP_002845673.1 229587172 7815423 complement(1166751..1167254) 1 NC_012633.1 hypothetical protein 1167254 7815423 RAF_ORF1141 Rickettsia africae ESF-5 hypothetical protein YP_002845673.1 1166751 R 347255 CDS YP_002845674.1 229587173 7815424 complement(1167223..1168950) 1 NC_012633.1 Glutathione-regulated potassium-efflux system protein KefB 1168950 kefB 7815424 kefB Rickettsia africae ESF-5 Glutathione-regulated potassium-efflux system protein KefB YP_002845674.1 1167223 R 347255 CDS YP_002845675.1 229587174 7815425 complement(1168947..1169273) 1 NC_012633.1 Iojap-related protein 1169273 7815425 RAF_ORF1143 Rickettsia africae ESF-5 Iojap-related protein YP_002845675.1 1168947 R 347255 CDS YP_002845676.1 229587175 7815426 1169429..1169668 1 NC_012633.1 BolA-like protein 1169668 bolA2 7815426 bolA2 Rickettsia africae ESF-5 BolA-like protein YP_002845676.1 1169429 D 347255 CDS YP_002845677.1 229587176 7815428 complement(1175659..1176579) 1 NC_012633.1 Cell surface antigen Sca9 1176579 sca9 7815428 sca9 Rickettsia africae ESF-5 Cell surface antigen Sca9 YP_002845677.1 1175659 R 347255 CDS YP_002845678.1 229587177 7815430 1177352..1177567 1 NC_012633.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1177567 infA 7815430 infA Rickettsia africae ESF-5 translation initiation factor IF-1 YP_002845678.1 1177352 D 347255 CDS YP_002845679.1 229587178 7815431 1177579..1178226 1 NC_012633.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1178226 maf 7815431 maf Rickettsia africae ESF-5 Maf-like protein YP_002845679.1 1177579 D 347255 CDS YP_002845680.1 229587179 7815432 complement(1178360..1178791) 1 NC_012633.1 DnaK suppressor-like protein 1178791 dksA 7815432 dksA Rickettsia africae ESF-5 DnaK suppressor-like protein YP_002845680.1 1178360 R 347255 CDS YP_002845681.1 229587180 7815433 complement(1178959..1179876) 1 NC_012633.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1179876 xerC 7815433 xerC Rickettsia africae ESF-5 site-specific tyrosine recombinase XerC YP_002845681.1 1178959 R 347255 CDS YP_002845682.1 229587181 7815434 1180046..1180327 1 NC_012633.1 Phasin family protein 1180327 7815434 RAF_ORF1160 Rickettsia africae ESF-5 Phasin family protein YP_002845682.1 1180046 D 347255 CDS YP_002845683.1 229587182 7815435 complement(1180375..1180977) 1 NC_012633.1 phospholipase D 1180977 pldA 7815435 pldA Rickettsia africae ESF-5 phospholipase D YP_002845683.1 1180375 R 347255 CDS YP_002845684.1 229587183 7815437 complement(1181755..1183233) 1 NC_012633.1 UbiD family decarboxylase 1183233 ubiD 7815437 ubiD Rickettsia africae ESF-5 UbiD family decarboxylase YP_002845684.1 1181755 R 347255 CDS YP_002845685.1 229587184 7815438 complement(1183387..1184961) 1 NC_012633.1 Parvulin-like peptidyl-prolyl isomerase 1184961 surA 7815438 surA Rickettsia africae ESF-5 Parvulin-like peptidyl-prolyl isomerase YP_002845685.1 1183387 R 347255 CDS YP_002845686.1 229587185 7815439 complement(1185155..1191436) 1 NC_012633.1 outer memberane protein OmpA 1191436 ompA 7815439 ompA Rickettsia africae ESF-5 outer memberane protein OmpA YP_002845686.1 1185155 R 347255 CDS YP_002845687.1 229587186 7815440 complement(1192074..1194308) 1 NC_012633.1 cell division protein FtsK 1194308 ftsK 7815440 ftsK Rickettsia africae ESF-5 cell division protein FtsK YP_002845687.1 1192074 R 347255 CDS YP_002845688.1 229587187 7815441 complement(1194477..1195346) 1 NC_012633.1 Putative acyltransferase 1195346 7815441 RAF_ORF1168 Rickettsia africae ESF-5 Putative acyltransferase YP_002845688.1 1194477 R 347255 CDS YP_002845689.1 229587188 7815442 1195502..1196281 1 NC_012633.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1196281 map 7815442 map Rickettsia africae ESF-5 methionine aminopeptidase YP_002845689.1 1195502 D 347255 CDS YP_002845690.1 229587189 7815444 1197202..1198185 1 NC_012633.1 UDP-phosphate alpha-N-acetylglucosaminyltransferase 1198185 mraY2 7815444 mraY2 Rickettsia africae ESF-5 UDP-phosphate alpha-N-acetylglucosaminyltransferase YP_002845690.1 1197202 D 347255 CDS YP_002845691.1 229587190 7815445 1198182..1198505 1 NC_012633.1 hypothetical protein 1198505 7815445 RAF_ORF1173 Rickettsia africae ESF-5 hypothetical protein YP_002845691.1 1198182 D 347255 CDS YP_002845692.1 229587191 7815446 complement(1198893..1199630) 1 NC_012633.1 hypothetical protein 1199630 7815446 RAF_ORF1174 Rickettsia africae ESF-5 hypothetical protein YP_002845692.1 1198893 R 347255 CDS YP_002845693.1 229587192 7815447 complement(1199877..1200560) 1 NC_012633.1 Putative outer surface protein 1200560 7815447 RAF_ORF1175 Rickettsia africae ESF-5 Putative outer surface protein YP_002845693.1 1199877 R 347255 CDS YP_002845694.1 229587193 7815448 complement(1200844..1201194) 1 NC_012633.1 Ferredoxin 1201194 fdxA 7815448 fdxA Rickettsia africae ESF-5 Ferredoxin YP_002845694.1 1200844 R 347255 CDS YP_002845695.1 229587194 7815449 complement(1201199..1201891) 1 NC_012633.1 Heme exporter protein C 1201891 ccmC 7815449 ccmC Rickettsia africae ESF-5 Heme exporter protein C YP_002845695.1 1201199 R 347255 CDS YP_002845696.1 229587195 7815450 complement(1201906..1202412) 1 NC_012633.1 cytosine deaminase 1202412 7815450 RAF_ORF1178 Rickettsia africae ESF-5 cytosine deaminase YP_002845696.1 1201906 R 347255 CDS YP_002845697.1 229587196 7815451 complement(1202393..1203313) 1 NC_012633.1 Cation diffusion facilitator family transporter 1203313 7815451 RAF_ORF1179 Rickettsia africae ESF-5 Cation diffusion facilitator family transporter YP_002845697.1 1202393 R 347255 CDS YP_002845698.1 229587197 7815452 1203480..1203959 1 NC_012633.1 17 kD surface antigen 1203959 omp 7815452 omp Rickettsia africae ESF-5 17 kD surface antigen YP_002845698.1 1203480 D 347255 CDS YP_002845699.1 229587198 7815453 1204090..1204554 1 NC_012633.1 Phosphatidylethanolamine-binding protein PEBP 1204554 7815453 RAF_ORF1181 Rickettsia africae ESF-5 Phosphatidylethanolamine-binding protein PEBP YP_002845699.1 1204090 D 347255 CDS YP_002845700.1 229587199 7815454 1204694..1205395 1 NC_012633.1 Zinc ABC transporter ATP-binding protein 1205395 znuC 7815454 znuC Rickettsia africae ESF-5 Zinc ABC transporter ATP-binding protein YP_002845700.1 1204694 D 347255 CDS YP_002845701.1 229587200 7815456 complement(1206660..1206956) 1 NC_012633.1 hypothetical protein 1206956 7815456 RAF_ORF1185 Rickettsia africae ESF-5 hypothetical protein YP_002845701.1 1206660 R 347255 CDS YP_002845702.1 229587201 7815457 complement(1207601..1210468) 1 NC_012633.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1210468 uvrA 7815457 uvrA Rickettsia africae ESF-5 excinuclease ABC subunit A YP_002845702.1 1207601 R 347255 CDS YP_002845703.1 229587202 7815458 1210571..1211029 1 NC_012633.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1211029 ssb 7815458 ssb Rickettsia africae ESF-5 single-stranded DNA-binding protein YP_002845703.1 1210571 D 347255 CDS YP_002845704.1 229587203 7815459 1211041..1211871 1 NC_012633.1 DAP2 dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein 1211871 7815459 RAF_ORF1188 Rickettsia africae ESF-5 DAP2 dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein YP_002845704.1 1211041 D 347255 CDS YP_002845705.1 229587204 7815460 1211912..1212205 1 NC_012633.1 MFS-type sugar transporter 1212205 7815460 RAF_ORF1189 Rickettsia africae ESF-5 MFS-type sugar transporter YP_002845705.1 1211912 D 347255 CDS YP_002845706.1 229587205 7815461 complement(1212296..1212502) 1 NC_012633.1 lysozyme 1212502 7815461 RAF_ORF1190 Rickettsia africae ESF-5 lysozyme YP_002845706.1 1212296 R 347255 CDS YP_002845707.1 229587206 7815463 1213541..1213858 1 NC_012633.1 hypothetical protein 1213858 7815463 RAF_ORF1191 Rickettsia africae ESF-5 hypothetical protein YP_002845707.1 1213541 D 347255 CDS YP_002845708.1 229587207 7815464 1214002..1215867 1 NC_012633.1 molecular chaperone; heat shock protein 90 1215867 htpG 7815464 htpG Rickettsia africae ESF-5 heat shock protein 90 YP_002845708.1 1214002 D 347255 CDS YP_002845709.1 229587208 7815465 1216046..1217290 1 NC_012633.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 1217290 hemA 7815465 hemA Rickettsia africae ESF-5 5-aminolevulinate synthase YP_002845709.1 1216046 D 347255 CDS YP_002845710.1 229587209 7815466 1218945..1220282 1 NC_012633.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1220282 tig 7815466 tig Rickettsia africae ESF-5 trigger factor YP_002845710.1 1218945 D 347255 CDS YP_002845711.1 229587210 7815467 complement(1220386..1221432) 1 NC_012633.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1221432 obgE 7815467 obgE Rickettsia africae ESF-5 GTPase ObgE YP_002845711.1 1220386 R 347255 CDS YP_002845712.1 229587211 7815468 complement(1221487..1222794) 1 NC_012633.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1222794 gltA 7815468 gltA Rickettsia africae ESF-5 type II citrate synthase YP_002845712.1 1221487 R 347255 CDS YP_002845713.1 229587212 7815469 complement(1223495..1224334) 1 NC_012633.1 uracil-DNA glycosylase 1224334 7815469 RAF_ORF1197 Rickettsia africae ESF-5 uracil-DNA glycosylase YP_002845713.1 1223495 R 347255 CDS YP_002845714.1 229587213 7815470 1224297..1225238 1 NC_012633.1 Ribosomal large subunit pseudouridine synthases RluD subfamily protein 1225238 7815470 RAF_ORF1198 Rickettsia africae ESF-5 Ribosomal large subunit pseudouridine synthases RluD subfamily protein YP_002845714.1 1224297 D 347255 CDS YP_002845715.1 229587214 7815472 1226885..1228459 1 NC_012633.1 fusion of hemK/trmB; N-terminal HemK domain transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; C-terminal; bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase 1228459 hemK 7815472 hemK Rickettsia africae ESF-5 bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase YP_002845715.1 1226885 D 347255 CDS YP_002845716.1 229587215 7815473 complement(1228425..1229363) 1 NC_012633.1 Sua5/YciO/YrdC/YwlC family putative translation factor protein 1229363 7815473 RAF_ORF1202 Rickettsia africae ESF-5 Sua5/YciO/YrdC/YwlC family putative translation factor protein YP_002845716.1 1228425 R 347255 CDS YP_002845717.1 229587216 7815474 complement(1229360..1231354) 1 NC_012633.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1231354 glyS 7815474 glyS Rickettsia africae ESF-5 glycyl-tRNA synthetase subunit beta YP_002845717.1 1229360 R 347255 CDS YP_002845718.1 229587217 7815475 complement(1231351..1232217) 1 NC_012633.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1232217 glyQ 7815475 glyQ Rickettsia africae ESF-5 glycyl-tRNA synthetase subunit alpha YP_002845718.1 1231351 R 347255 CDS YP_002845719.1 229587218 7815476 complement(1232249..1232656) 1 NC_012633.1 Toxin of toxin-antitoxin (TA) system VapC, containing PIN domain for nucleic acid binding 1232656 vapC3 7815476 vapC3 Rickettsia africae ESF-5 Toxin of toxin-antitoxin (TA) system VapC, containing PIN domain for nucleic acid binding YP_002845719.1 1232249 R 347255 CDS YP_002845720.1 229587219 7815477 complement(1232653..1232838) 1 NC_012633.1 Putative antitoxin of toxin-antitoxin (TA) system 1232838 7815477 RAF_ORF1206 Rickettsia africae ESF-5 Putative antitoxin of toxin-antitoxin (TA) system YP_002845720.1 1232653 R 347255 CDS YP_002845721.1 229587220 7815478 complement(1232986..1233615) 1 NC_012633.1 hypothetical protein 1233615 7815478 RAF_ORF1207 Rickettsia africae ESF-5 hypothetical protein YP_002845721.1 1232986 R 347255 CDS YP_002845722.1 229587221 7815480 complement(1235086..1236036) 1 NC_012633.1 hypothetical protein 1236036 7815480 RAF_ORF1211 Rickettsia africae ESF-5 hypothetical protein YP_002845722.1 1235086 R 347255 CDS YP_002845723.1 229587222 7815481 complement(1236046..1236681) 1 NC_012633.1 hypothetical protein 1236681 7815481 RAF_ORF1212 Rickettsia africae ESF-5 hypothetical protein YP_002845723.1 1236046 R 347255 CDS YP_002845724.1 229587223 7815482 complement(1236756..1238327) 1 NC_012633.1 hypothetical protein 1238327 7815482 RAF_ORF1213 Rickettsia africae ESF-5 hypothetical protein YP_002845724.1 1236756 R 347255 CDS YP_002845725.1 229587224 7815483 1238526..1241162 1 NC_012633.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1241162 alaS 7815483 alaS Rickettsia africae ESF-5 alanyl-tRNA synthetase YP_002845725.1 1238526 D 347255 CDS YP_002845726.1 229587225 7815484 complement(1241371..1242108) 1 NC_012633.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1242108 truA 7815484 truA Rickettsia africae ESF-5 tRNA pseudouridine synthase A YP_002845726.1 1241371 R 347255 CDS YP_002845727.1 229587226 7815485 complement(1242204..1244108) 1 NC_012633.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1244108 rpoD 7815485 rpoD Rickettsia africae ESF-5 RNA polymerase sigma factor RpoD YP_002845727.1 1242204 R 347255 CDS YP_002845728.1 229587227 7815486 complement(1244153..1245940) 1 NC_012633.1 synthesizes RNA primers at the replication forks; DNA primase 1245940 dnaG 7815486 dnaG Rickettsia africae ESF-5 DNA primase YP_002845728.1 1244153 R 347255 CDS YP_002845729.1 229587228 7815487 complement(1245945..1246559) 1 NC_012633.1 dolichol kinase 1246559 sec59 7815487 sec59 Rickettsia africae ESF-5 dolichol kinase YP_002845729.1 1245945 R 347255 CDS YP_002845730.1 229587229 7815488 1246758..1247315 1 NC_012633.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1247315 greA 7815488 greA Rickettsia africae ESF-5 transcription elongation factor GreA YP_002845730.1 1246758 D 347255 CDS YP_002845731.1 229587230 7815489 complement(1247474..1247872) 1 NC_012633.1 NAD(P) transhydrogenase subunit alpha 1247872 pntA2 7815489 pntA2 Rickettsia africae ESF-5 NAD(P) transhydrogenase subunit alpha YP_002845731.1 1247474 R 347255 CDS YP_002845732.1 229587231 7815490 complement(1247869..1248993) 1 NC_012633.1 NAD(P) transhydrogenase subunit alpha 1248993 pntA1 7815490 pntA1 Rickettsia africae ESF-5 NAD(P) transhydrogenase subunit alpha YP_002845732.1 1247869 R 347255 CDS YP_002845733.1 229587232 7815491 1249069..1249707 1 NC_012633.1 Outer membrane lipoprotein-sorting protein LolA 1249707 lolA 7815491 lolA Rickettsia africae ESF-5 Outer membrane lipoprotein-sorting protein LolA YP_002845733.1 1249069 D 347255 CDS YP_002845734.1 229587233 7815493 1249861..1251462 1 NC_012633.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; rhe tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1251462 dnaX 7815493 dnaX Rickettsia africae ESF-5 DNA polymerase III subunits gamma and tau YP_002845734.1 1249861 D 347255 CDS YP_002845735.1 229587234 7815494 1251482..1251805 1 NC_012633.1 hypothetical protein 1251805 7815494 RAF_ORF1224 Rickettsia africae ESF-5 hypothetical protein YP_002845735.1 1251482 D 347255 CDS YP_002845736.1 229587235 7815495 complement(1252670..1253365) 1 NC_012633.1 Putative aspartyl protease 1253365 7815495 RAF_ORF1225 Rickettsia africae ESF-5 Putative aspartyl protease YP_002845736.1 1252670 R 347255 CDS YP_002845737.1 229587236 7815496 complement(1254553..1254792) 1 NC_012633.1 Antitoxin of toxin-antitoxin (TA) system StbD 1254792 7815496 RAF_ORF1226 Rickettsia africae ESF-5 Antitoxin of toxin-antitoxin (TA) system StbD YP_002845737.1 1254553 R 347255 CDS YP_002845738.1 229587237 7815497 complement(1254998..1255720) 1 NC_012633.1 Glutamine ABC transporter ATP-binding protein 1255720 glnQ 7815497 glnQ Rickettsia africae ESF-5 Glutamine ABC transporter ATP-binding protein YP_002845738.1 1254998 R 347255 CDS YP_002845739.1 229587238 7815820 complement(1255724..1256488) 1 NC_012633.1 beta-lactamase 1256488 phnP 7815820 phnP Rickettsia africae ESF-5 beta-lactamase YP_002845739.1 1255724 R 347255 CDS YP_002845740.1 229587239 7815821 1256503..1257150 1 NC_012633.1 hypothetical protein 1257150 7815821 RAF_ORF1229 Rickettsia africae ESF-5 hypothetical protein YP_002845740.1 1256503 D 347255 CDS YP_002845741.1 229587240 7815822 1257244..1257507 1 NC_012633.1 DNA-damage-inducible protein J 1257507 dinJ 7815822 dinJ Rickettsia africae ESF-5 DNA-damage-inducible protein J YP_002845741.1 1257244 D 347255 CDS YP_002845742.1 229587241 7815823 1257602..1257745 1 NC_012633.1 hypothetical protein 1257745 7815823 RAF_ORF1231 Rickettsia africae ESF-5 hypothetical protein YP_002845742.1 1257602 D 347255 CDS YP_002845743.1 229587242 7815824 1257854..1258963 1 NC_012633.1 Putative permease 1258963 7815824 RAF_ORF1232 Rickettsia africae ESF-5 Putative permease YP_002845743.1 1257854 D 347255 CDS YP_002845744.1 229587243 7815825 complement(1258969..1259433) 1 NC_012633.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 1259433 holC 7815825 holC Rickettsia africae ESF-5 DNA polymerase III subunit chi YP_002845744.1 1258969 R 347255 CDS YP_002845745.1 229587244 7815827 complement(1259633..1260778) 1 NC_012633.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1260778 dapE 7815827 dapE Rickettsia africae ESF-5 succinyl-diaminopimelate desuccinylase YP_002845745.1 1259633 R 347255 CDS YP_002845746.1 229587245 7815828 complement(1260832..1261434) 1 NC_012633.1 Type I restriction/modification enzyme endonuclease S subunit 1261434 7815828 RAF_ORF1235 Rickettsia africae ESF-5 Type I restriction/modification enzyme endonuclease S subunit YP_002845746.1 1260832 R 347255 CDS YP_002845747.1 229587246 7815829 complement(1261547..1261744) 1 NC_012633.1 hypothetical protein 1261744 7815829 RAF_ORF1236 Rickettsia africae ESF-5 hypothetical protein YP_002845747.1 1261547 R 347255 CDS YP_002845748.1 229587247 7815831 complement(1263221..1263451) 1 NC_012633.1 hypothetical protein 1263451 7815831 RAF_ORF1240 Rickettsia africae ESF-5 hypothetical protein YP_002845748.1 1263221 R 347255 CDS YP_002845749.1 229587248 7815832 1263620..1264444 1 NC_012633.1 Na+/H+ antiporter NhaA 1264444 nhaA 7815832 nhaA Rickettsia africae ESF-5 Na+/H+ antiporter NhaA YP_002845749.1 1263620 D 347255 CDS YP_002845750.1 229587249 7815833 complement(1264533..1265048) 1 NC_012633.1 hypothetical protein 1265048 7815833 RAF_ORF1242 Rickettsia africae ESF-5 hypothetical protein YP_002845750.1 1264533 R 347255 CDS YP_002845751.1 229587250 7815834 complement(1265045..1265674) 1 NC_012633.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1265674 lipB 7815834 lipB Rickettsia africae ESF-5 lipoate-protein ligase B YP_002845751.1 1265045 R 347255 CDS YP_002845752.1 229587251 7815835 complement(1265671..1266414) 1 NC_012633.1 Negative regulator of beta-lactamase expression 1266414 ampD2 7815835 ampD2 Rickettsia africae ESF-5 Negative regulator of beta-lactamase expression YP_002845752.1 1265671 R 347255 CDS YP_002845753.1 229587252 7815837 complement(1266911..1267246) 1 NC_012633.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1267246 rpsP 7815837 rpsP Rickettsia africae ESF-5 30S ribosomal protein S16 YP_002845753.1 1266911 R 347255 CDS YP_002845754.1 229587253 7815838 complement(1267263..1267433) 1 NC_012633.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1267433 rpmG 7815838 rpmG Rickettsia africae ESF-5 50S ribosomal protein L33 YP_002845754.1 1267263 R 347255 CDS YP_002845755.1 229587254 7815839 complement(1267655..1269487) 1 NC_012633.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1269487 mutL 7815839 mutL Rickettsia africae ESF-5 DNA mismatch repair protein YP_002845755.1 1267655 R 347255 CDS YP_002845756.1 229587255 7815840 complement(1269484..1269648) 1 NC_012633.1 hypothetical protein 1269648 7815840 RAF_ORF1248 Rickettsia africae ESF-5 hypothetical protein YP_002845756.1 1269484 R 347255 CDS YP_002845757.1 229587256 7815843 1272546..1273820 1 NC_012633.1 Proline/betaine transporter 1273820 proP7 7815843 proP7 Rickettsia africae ESF-5 Proline/betaine transporter YP_002845757.1 1272546 D 347255 CDS YP_002845758.1 229587257 7815844 1273804..1274643 1 NC_012633.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1274643 hemF 7815844 hemF Rickettsia africae ESF-5 coproporphyrinogen III oxidase YP_002845758.1 1273804 D 347255 CDS YP_002845759.1 229587258 7815846 complement(1275659..1276096) 1 NC_012633.1 hypothetical protein 1276096 7815846 RAF_ORF1257 Rickettsia africae ESF-5 hypothetical protein YP_002845759.1 1275659 R 347255 CDS YP_002845760.1 229587259 7815847 complement(1276108..1277148) 1 NC_012633.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1277148 hemH 7815847 hemH Rickettsia africae ESF-5 ferrochelatase YP_002845760.1 1276108 R 347255 CDS YP_002845761.1 229587260 7815848 complement(1277105..1278145) 1 NC_012633.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1278145 hemE 7815848 hemE Rickettsia africae ESF-5 uroporphyrinogen decarboxylase YP_002845761.1 1277105 R 347255 CDS YP_002845762.1 228478452 7803247 1..2223 1 NC_012634.1 Unknown (DnaA-like) 2223 7803247 RAF_pORF1260 Rickettsia africae ESF-5 Unknown (DnaA-like) YP_002845762.1 1 D 347255 CDS YP_002845763.1 228478453 7803237 2263..2964 1 NC_012634.1 hypothetical protein 2964 7803237 RAF_pORF1261 Rickettsia africae ESF-5 hypothetical protein YP_002845763.1 2263 D 347255 CDS YP_002845764.1 228478454 7803238 3122..3706 1 NC_012634.1 Site-specific recombinase, DNA invertase Pin-like protein 3706 7803238 RAF_pORF1262 Rickettsia africae ESF-5 Site-specific recombinase, DNA invertase Pin-like protein YP_002845764.1 3122 D 347255 CDS YP_002845765.1 228478455 7803239 complement(3862..4503) 1 NC_012634.1 Transposase and inactivated derivative 4503 7803239 RAF_pORF1263 Rickettsia africae ESF-5 Transposase and inactivated derivative YP_002845765.1 3862 R 347255 CDS YP_002845766.1 228478456 7803240 complement(4676..5761) 1 NC_012634.1 Transposase and inactivated derivative 5761 7803240 RAF_pORF1264 Rickettsia africae ESF-5 Transposase and inactivated derivative YP_002845766.1 4676 R 347255 CDS YP_002845767.1 228478457 7803241 complement(5805..6203) 1 NC_012634.1 hypothetical protein 6203 7803241 RAF_pORF1265 Rickettsia africae ESF-5 hypothetical protein YP_002845767.1 5805 R 347255 CDS YP_002845768.1 228478458 7803242 complement(6236..6535) 1 NC_012634.1 hypothetical protein 6535 7803242 RAF_pORF1266 Rickettsia africae ESF-5 hypothetical protein YP_002845768.1 6236 R 347255 CDS YP_002845769.1 228478459 7803243 complement(7255..7626) 1 NC_012634.1 hypothetical protein 7626 7803243 RAF_pORF1267 Rickettsia africae ESF-5 hypothetical protein YP_002845769.1 7255 R 347255 CDS YP_002845770.1 228478460 7803244 complement(7776..10421) 1 NC_012634.1 Cell surface antigen Sca12 10421 sca12 7803244 sca12 Rickettsia africae ESF-5 Cell surface antigen Sca12 YP_002845770.1 7776 R 347255 CDS YP_002845771.1 228478461 7803245 10574..11047 1 NC_012634.1 hypothetical protein 11047 7803245 RAF_pORF1269 Rickettsia africae ESF-5 hypothetical protein YP_002845771.1 10574 D 347255 CDS YP_002845772.1 228478462 7803246 complement(11231..11902) 1 NC_012634.1 Plasmid stability protein ParA 11902 parA2 7803246 parA2 Rickettsia africae ESF-5 Plasmid stability protein ParA YP_002845772.1 11231 R 347255 CDS