-- dump date 20140619_163641 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 122586000001 SEQ_END SEQ_END NC_003112.2 2272360 2272360 DR NC_003112.2; contig end 2272360..2272360 Neisseria meningitidis MC58 NP_273067.1 CDS NMB0001 NC_003112.2 7 498 R identified by similarity to EGAD:160712; match to protein family HMM PF00583; acetyltransferase complement(7..498) Neisseria meningitidis MC58 902103 NP_273068.1 CDS NMB0002 NC_003112.2 502 897 R hypothetical protein complement(502..897) Neisseria meningitidis MC58 902104 NP_273069.1 CDS gltX NC_003112.2 918 2312 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(918..2312) Neisseria meningitidis MC58 902105 NP_273070.1 CDS NMB0004 NC_003112.2 2517 3161 R identified by similarity to EGAD:132655; match to protein family HMM PF02698; EpiH/GdmH-like protein complement(2517..3161) Neisseria meningitidis MC58 902106 NP_273071.1 CDS arsC NC_003112.2 3158 3511 R identified by similarity to EGAD:124632; match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase complement(3158..3511) Neisseria meningitidis MC58 902107 NP_273072.1 CDS NMB0006 NC_003112.2 3635 4117 D identified by similarity to EGAD:143277; thioredoxin-like protein 3635..4117 Neisseria meningitidis MC58 902108 NP_273073.1 CDS ftsE NC_003112.2 4311 4961 D identified by similarity to EGAD:140012; match to protein family HMM PF00005; match to protein family HMM TIGR00960; ABC transporter ATP-binding protein 4311..4961 Neisseria meningitidis MC58 902109 NP_273074.1 CDS NMB0008 NC_003112.2 4958 5875 D identified by similarity to EGAD:140175; match to protein family HMM PF02687; match to protein family HMM TIGR00439; cell division protein FtsX 4958..5875 Neisseria meningitidis MC58 902110 NP_273075.1 CDS NMB0009 NC_003112.2 5966 6214 D identified by similarity to EGAD:50503; match to protein family HMM PF01722; BolA/YrbA family protein 5966..6214 Neisseria meningitidis MC58 902111 NP_273076.1 CDS pgk NC_003112.2 6281 7492 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(6281..7492) Neisseria meningitidis MC58 902112 NP_273077.1 CDS murA NC_003112.2 7573 8826 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(7573..8826) Neisseria meningitidis MC58 902113 NP_273078.1 CDS NMB0012 NC_003112.2 9346 10317 R identified by similarity to EGAD:30886; match to protein family HMM PF03741; hypothetical protein complement(9346..10317) Neisseria meningitidis MC58 902115 NP_273079.1 CDS NMB0013 NC_003112.2 10350 10799 R identified by similarity to EGAD:90450; match to protein family HMM PF04323; hypothetical protein complement(10350..10799) Neisseria meningitidis MC58 902116 NP_273080.1 CDS kdtA NC_003112.2 10840 12111 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(10840..12111) Neisseria meningitidis MC58 902117 NP_273081.1 CDS gnd NC_003112.2 12174 13622 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(12174..13622) Neisseria meningitidis MC58 902118 NP_273083.1 CDS lpxC NC_003112.2 15221 16144 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(15221..16144) Neisseria meningitidis MC58 902120 NP_273084.1 CDS pilE NC_003112.2 17229 17741 R identified by similarity to GP:349016; match to protein family HMM PF00114; match to protein family HMM PF07963; match to protein family HMM TIGR02532; pilin PilE complement(17229..17741) Neisseria meningitidis MC58 902121 YP_338284.1 CDS NMB0019 NC_003112.2 18517 18927 R identified by similarity to GP:349528; match to protein family HMM PF00114; pilS cassette complement(18517..18927) Neisseria meningitidis MC58 902122 YP_338285.1 CDS NMB0020 NC_003112.2 19267 19641 R identified by similarity to EGAD:138647; match to protein family HMM PF00114; pilS cassette complement(19267..19641) Neisseria meningitidis MC58 902123 YP_338286.1 CDS NMB0021 NC_003112.2 19918 20292 R identified by similarity to EGAD:11801; pilS cassette complement(19918..20292) Neisseria meningitidis MC58 902124 YP_338287.1 CDS NMB0022 NC_003112.2 20832 21170 R identified by similarity to EGAD:40711; pilS cassette complement(20832..21170) Neisseria meningitidis MC58 902125 YP_338288.1 CDS NMB0023 NC_003112.2 21470 21877 R identified by similarity to EGAD:11802; match to protein family HMM PF00114; pilS cassette complement(21470..21877) Neisseria meningitidis MC58 902126 YP_338289.1 CDS NMB0024 NC_003112.2 21891 22487 R identified by similarity to EGAD:32664; pilS cassette complement(21891..22487) Neisseria meningitidis MC58 902127 YP_338290.1 CDS NMB0025 NC_003112.2 22825 23502 R identified by similarity to EGAD:138648; large pilS cassette complement(22825..23502) Neisseria meningitidis MC58 902128 NP_273092.1 CDS NMB0026 NC_003112.2 23528 23875 R identified by similarity to EGAD:13664; pilS cassette complement(23528..23875) Neisseria meningitidis MC58 902129 NP_273093.1 CDS NMB0027 NC_003112.2 23904 24233 R Suggested gene symbol is fbp (PMID:1371354).; identified by similarity to EGAD:15191; match to protein family HMM PF00254; peptidyl-prolyl cis-trans isomerase complement(23904..24233) Neisseria meningitidis MC58 902130 NP_273094.1 CDS NMB0028 NC_003112.2 24311 24529 R hypothetical protein complement(24311..24529) Neisseria meningitidis MC58 902131 NP_273095.1 CDS hprA NC_003112.2 24651 25604 D identified by similarity to EGAD:28541; match to protein family HMM PF00389; match to protein family HMM PF02826; glycerate dehydrogenase 24651..25604 Neisseria meningitidis MC58 902132 NP_273096.1 CDS metG NC_003112.2 25679 27736 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(25679..27736) Neisseria meningitidis MC58 902133 NP_273097.1 CDS glmS NC_003112.2 27852 29690 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(27852..29690) Neisseria meningitidis MC58 902134 NP_273098.1 CDS NMB0032 NC_003112.2 29966 30493 D hypothetical protein 29966..30493 Neisseria meningitidis MC58 902135 NP_273099.1 CDS NMB0033 NC_003112.2 30911 32236 R identified by similarity to GP:974447; match to protein family HMM PF03562; match to protein family HMM PF06725; membrane-bound lytic murein transglycosylase A complement(30911..32236) Neisseria meningitidis MC58 902136 NP_273100.1 CDS NMB0034 NC_003112.2 32447 33286 D identified by similarity to EGAD:90733; match to protein family HMM PF03239; hypothetical protein 32447..33286 Neisseria meningitidis MC58 902137 NP_273101.1 CDS NMB0035 NC_003112.2 33283 34449 D identified by similarity to EGAD:90734; match to protein family HMM PF04302; hypothetical protein 33283..34449 Neisseria meningitidis MC58 902138 NP_273102.1 CDS NMB0036 NC_003112.2 34713 35978 D identified by similarity to EGAD:11971; match to protein family HMM PF04261; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413; hypothetical protein 34713..35978 Neisseria meningitidis MC58 902139 NP_273103.1 CDS phnA NC_003112.2 36050 36379 R identified by similarity to EGAD:35919; match to protein family HMM PF03831; match to protein family HMM TIGR00686; phnA protein complement(36050..36379) Neisseria meningitidis MC58 902140 NP_273104.1 CDS glmU NC_003112.2 36454 37824 R identified by similarity to EGAD:40827; match to protein family HMM PF00132; match to protein family HMM PF00483; match to protein family HMM TIGR01173; UDP-N-acetylglucosamine pyrophosphorylase complement(36454..37824) Neisseria meningitidis MC58 902141 NP_273107.1 CDS NMB0041 NC_003112.2 38916 39917 D identified by similarity to EGAD:159451; match to protein family HMM PF01547; match to protein family HMM TIGR01254; ABC transporter substrate-binding protein 38916..39917 Neisseria meningitidis MC58 902144 NP_273108.1 CDS NMB0042 NC_003112.2 40011 40859 D identified by similarity to GP:2708660; match to protein family HMM PF00924; hypothetical protein 40011..40859 Neisseria meningitidis MC58 902145 NP_273109.1 CDS NMB0043 NC_003112.2 40885 41370 D identified by similarity to EGAD:32599; match to protein family HMM PF02464; match to protein family HMM TIGR00199; hypothetical protein 40885..41370 Neisseria meningitidis MC58 902146 NP_273110.1 CDS pilB NC_003112.2 41472 43040 R this is a fusion of 3 domains, an N-termianl thioredoxin domain, and 2 domains at the C-terminus that are methionine sulfoxide reductases, MsrA and MsrB; methionine is modified to form methionine sulfoxide during normal cellular processes and due to oxidat; trifunctional thioredoxin/methionine sulfoxide reductase A/B protein complement(41472..43040) Neisseria meningitidis MC58 902147 NP_273111.1 CDS pilA NC_003112.2 43186 44451 D identified by similarity to EGAD:6624; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle protein 43186..44451 Neisseria meningitidis MC58 902148 NP_273113.1 CDS NMB0047 NC_003112.2 45079 45363 D identified by similarity to GP:2570056; match to protein family HMM PF01541; hypothetical protein 45079..45363 Neisseria meningitidis MC58 902150 NP_273115.1 CDS NMB0050 NC_003112.2 53030 55180 R identified by similarity to EGAD:28668; match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667; hypothetical protein complement(53030..55180) Neisseria meningitidis MC58 902152 NP_273116.1 CDS NMB0051 NC_003112.2 55466 56692 R identified by similarity to EGAD:32627; match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility protein complement(55466..56692) Neisseria meningitidis MC58 902153 NP_273117.1 CDS pilT-1 NC_003112.2 56855 57898 R identified by similarity to GP:3328331; match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility protein PilT complement(56855..57898) Neisseria meningitidis MC58 902154 NP_273118.1 CDS NMB0053 NC_003112.2 58018 58704 D identified by similarity to EGAD:10097; match to protein family HMM PF01168; match to protein family HMM TIGR00044; hypothetical protein 58018..58704 Neisseria meningitidis MC58 902155 NP_273119.1 CDS NMB0054 NC_003112.2 58704 59111 D hypothetical protein 58704..59111 Neisseria meningitidis MC58 902156 NP_273120.1 CDS proC NC_003112.2 59160 59951 D identified by similarity to EGAD:34246; match to protein family HMM PF01089; match to protein family HMM TIGR00112; pyrroline-5-carboxylate reductase 59160..59951 Neisseria meningitidis MC58 902157 NP_273121.1 CDS dksA NC_003112.2 60098 60514 D identified by similarity to GP:3064140; match to protein family HMM PF01258; match to protein family HMM TIGR02420; DnaK suppressor protein 60098..60514 Neisseria meningitidis MC58 902158 NP_273124.1 CDS dnaJ NC_003112.2 66979 68100 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 66979..68100 Neisseria meningitidis MC58 902166 NP_273125.1 CDS NMB0060 NC_003112.2 68296 70314 D identified by similarity to EGAD:133403; match to protein family HMM PF03169; match to protein family HMM TIGR00728; match to protein family HMM TIGR00733; hypothetical protein 68296..70314 Neisseria meningitidis MC58 902167 YP_008920703.1 CDS rfbC NC_003112.2 70358 70930 R dTDP-4-dehydrorhamnose 3,5-epimerase complement(70358..70930) Neisseria meningitidis MC58 902168 NP_273126.1 CDS rfbA-1 NC_003112.2 70969 71835 R identified by similarity to EGAD:23719; match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase complement(70969..71835) Neisseria meningitidis MC58 902169 NP_273127.1 CDS rfbB-1 NC_003112.2 71898 72965 R identified by similarity to EGAD:40672; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-D-glucose 4,6-dehydratase complement(71898..72965) Neisseria meningitidis MC58 902170 NP_273128.1 CDS galE NC_003112.2 73081 74100 R identified by similarity to EGAD:16384; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase complement(73081..74100) Neisseria meningitidis MC58 902171 NP_273129.1 CDS NMB0065 NC_003112.2 74483 75409 D hypothetical protein 74483..75409 Neisseria meningitidis MC58 902172 NP_273130.1 CDS ermC NC_003112.2 75694 76428 D identified by similarity to EGAD:8424; match to protein family HMM PF00398; rRNA adenine N-6-methyltransferase 75694..76428 Neisseria meningitidis MC58 902173 NP_273131.1 CDS NMB0067 NC_003112.2 76613 77290 R identified by similarity to GP:530041; polysialic acid capsule biosynthesis protein SiaD complement(76613..77290) Neisseria meningitidis MC58 903210 NP_273132.1 CDS siaC NC_003112.2 77374 78423 R identified by similarity to EGAD:19609; match to protein family HMM PF01354; match to protein family HMM PF03102; polysialic acid capsule biosynthesis protein SiaC complement(77374..78423) Neisseria meningitidis MC58 902174 NP_273133.1 CDS siaB NC_003112.2 78424 79110 R identified by similarity to EGAD:14454; match to protein family HMM PF02348; polysialic acid capsule biosynthesis protein SiaB complement(78424..79110) Neisseria meningitidis MC58 902175 NP_273134.1 CDS synX NC_003112.2 79114 80247 R identified by similarity to GP:460145; match to protein family HMM PF02350; polysialic acid capsule biosynthesis protein SynX complement(79114..80247) Neisseria meningitidis MC58 902176 NP_273135.1 CDS ctrA NC_003112.2 80382 81557 D identified by similarity to EGAD:23947; match to protein family HMM PF02563; capsule polysaccharide export outer membrane protein 80382..81557 Neisseria meningitidis MC58 902177 NP_273136.1 CDS ctrB NC_003112.2 81572 82735 D identified by similarity to EGAD:20633; match to protein family HMM PF02706; match to protein family HMM TIGR01010; capsule polysaccharide export inner-membrane protein 81572..82735 Neisseria meningitidis MC58 902178 NP_273137.1 CDS ctrC NC_003112.2 82735 83532 D identified by similarity to EGAD:15907; match to protein family HMM PF01061; capsule polysaccharide export inner-membrane protein 82735..83532 Neisseria meningitidis MC58 902179 NP_273138.1 CDS ctrD NC_003112.2 83529 84179 D identified by similarity to EGAD:15804; match to protein family HMM PF00005; capsule polysaccharide export ATP-binding protein CtrD 83529..84179 Neisseria meningitidis MC58 902180 NP_273139.1 CDS NMB0075 NC_003112.2 84243 86516 D identified by similarity to EGAD:97859; match to protein family HMM PF00575; transcriptional accessory protein Tex 84243..86516 Neisseria meningitidis MC58 902181 NP_273140.1 CDS NMB0077 NC_003112.2 87536 87886 D identified by similarity to EGAD:150447; site-specific DNA methylase, truncation 87536..87886 Neisseria meningitidis MC58 903209 NP_273141.1 CDS NMB0078 NC_003112.2 87929 88585 D identified by similarity to EGAD:19406; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase, truncation 87929..88585 Neisseria meningitidis MC58 903208 NP_273142.1 CDS rfbB-2 NC_003112.2 88701 89768 D identified by similarity to EGAD:40672; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-D-glucose 4,6-dehydratase 88701..89768 Neisseria meningitidis MC58 902183 NP_273143.1 CDS rfbA-2 NC_003112.2 89831 90697 D identified by similarity to EGAD:23719; match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 89831..90697 Neisseria meningitidis MC58 902184 NP_273144.1 CDS NMB0081 NC_003112.2 90736 91290 D identified by similarity to GP:3132257; match to protein family HMM PF00908; match to protein family HMM TIGR01221; dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase 90736..91290 Neisseria meningitidis MC58 902185 NP_273145.1 CDS lipA NC_003112.2 91315 93429 D identified by similarity to EGAD:15481; match to protein family HMM PF05159; capsule polysaccharide modification protein 91315..93429 Neisseria meningitidis MC58 902186 NP_273146.1 CDS lipB NC_003112.2 93566 94825 D identified by similarity to EGAD:7740; match to protein family HMM PF05159; capsule polysaccharide modification protein 93566..94825 Neisseria meningitidis MC58 902187 NP_273147.1 CDS gltS NC_003112.2 96815 98029 D identified by similarity to EGAD:28525; match to protein family HMM PF03616; match to protein family HMM TIGR00210; sodium/glutamate symport carrier protein 96815..98029 Neisseria meningitidis MC58 902189 NP_273148.1 CDS NMB0086 NC_003112.2 98128 99144 D hypothetical protein 98128..99144 Neisseria meningitidis MC58 902190 NP_273149.1 CDS NMB0087 NC_003112.2 99155 99352 D hypothetical protein 99155..99352 Neisseria meningitidis MC58 902191 NP_273150.1 CDS NMB0088 NC_003112.2 99777 101177 R identified by similarity to EGAD:16317; match to protein family HMM PF03349; outer membrane protein P1 complement(99777..101177) Neisseria meningitidis MC58 902192 NP_273151.1 CDS pykA NC_003112.2 101492 102964 R identified by similarity to EGAD:21471; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; pyruvate kinase complement(101492..102964) Neisseria meningitidis MC58 902193 NP_273152.1 CDS NMB0091 NC_003112.2 104406 104642 D hypothetical protein 104406..104642 Neisseria meningitidis MC58 902195 NP_273153.1 CDS NMB0092 NC_003112.2 104636 104863 D hypothetical protein 104636..104863 Neisseria meningitidis MC58 902196 NP_273154.1 CDS NMB0093 NC_003112.2 104863 104949 D hypothetical protein 104863..104949 Neisseria meningitidis MC58 902197 NP_273159.1 CDS NMB0100 NC_003112.2 109631 109777 R hypothetical protein complement(109631..109777) Neisseria meningitidis MC58 902204 NP_273160.1 CDS NMB0102 NC_003112.2 110615 111133 D hypothetical protein 110615..111133 Neisseria meningitidis MC58 902206 NP_273161.1 CDS NMB0103 NC_003112.2 111409 111903 R identified by similarity to GP:2909665; match to protein family HMM PF03412; bacteriocin resistance protein complement(111409..111903) Neisseria meningitidis MC58 902207 NP_273162.1 CDS NMB0104 NC_003112.2 112406 113080 R hypothetical protein complement(112406..113080) Neisseria meningitidis MC58 902208 NP_273163.1 CDS NMB0105 NC_003112.2 113362 114204 R identified by similarity to EGAD:108538; match to protein family HMM PF00583; PhnO-like protein complement(113362..114204) Neisseria meningitidis MC58 902209 NP_273164.1 CDS pyrB NC_003112.2 114443 115363 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 114443..115363 Neisseria meningitidis MC58 902210 NP_273165.1 CDS pyrI NC_003112.2 115373 115831 D involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 115373..115831 Neisseria meningitidis MC58 902211 NP_273166.1 CDS NMB0108 NC_003112.2 115896 116561 D hypothetical protein 115896..116561 Neisseria meningitidis MC58 902212 NP_273167.1 CDS NMB0109 NC_003112.2 116624 117955 R identified by similarity to EGAD:109565; match to protein family HMM PF01476; hypothetical protein complement(116624..117955) Neisseria meningitidis MC58 902213 NP_273168.1 CDS def NC_003112.2 118025 118528 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 118025..118528 Neisseria meningitidis MC58 902214 NP_273169.1 CDS fmt NC_003112.2 118615 119541 D identified by similarity to EGAD:24704; match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR00460; methionyl-tRNA formyltransferase 118615..119541 Neisseria meningitidis MC58 902215 NP_273170.1 CDS rsmB NC_003112.2 119620 120879 D identified by similarity to EGAD:36279; match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; 16S RNA methyltransferase 119620..120879 Neisseria meningitidis MC58 902216 NP_273171.1 CDS NMB0113 NC_003112.2 120899 121441 D hypothetical protein 120899..121441 Neisseria meningitidis MC58 902217 NP_273172.1 CDS NMB0114 NC_003112.2 121441 123561 D identified by similarity to EGAD:163355; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; nitrogen regulation protein NtrY 121441..123561 Neisseria meningitidis MC58 902218 NP_273173.1 CDS ntrX NC_003112.2 123554 124831 D identified by similarity to EGAD:5624; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199; nitrogen assimilation regulatory protein NtrX 123554..124831 Neisseria meningitidis MC58 902219 NP_273174.1 CDS dprA NC_003112.2 124922 126115 D identified by similarity to EGAD:27998; match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA processing protein DprA 124922..126115 Neisseria meningitidis MC58 902220 NP_273175.1 CDS NMB0117 NC_003112.2 126141 126602 D identified by similarity to EGAD:6532; match to protein family HMM PF04361; smg protein 126141..126602 Neisseria meningitidis MC58 902221 NP_273176.1 CDS topA NC_003112.2 126674 128980 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I 126674..128980 Neisseria meningitidis MC58 902222 NP_273177.1 CDS NMB0119 NC_003112.2 129053 129748 R hypothetical protein complement(129053..129748) Neisseria meningitidis MC58 902223 NP_273178.1 CDS NMB0120 NC_003112.2 129768 130319 R hypothetical protein complement(129768..130319) Neisseria meningitidis MC58 902224 NP_273179.1 CDS NMB0121 NC_003112.2 130438 130815 D identified by similarity to EGAD:28447; match to protein family HMM PF01381; hypothetical protein 130438..130815 Neisseria meningitidis MC58 902225 NP_273180.1 CDS NMB0122 NC_003112.2 130904 131473 D identified by similarity to EGAD:7463; match to protein family HMM PF03602; match to protein family HMM TIGR00095; hypothetical protein 130904..131473 Neisseria meningitidis MC58 902226 NP_273181.1 CDS NMB0123 NC_003112.2 131596 131847 D identified by similarity to EGAD:13273; match to protein family HMM PF00037; ferredoxin, 4Fe-4S type 131596..131847 Neisseria meningitidis MC58 902227 NP_273182.1 CDS tufB NC_003112.2 132264 133448 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 132264..133448 Neisseria meningitidis MC58 902231 NP_273183.1 CDS secE NC_003112.2 133645 133923 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 133645..133923 Neisseria meningitidis MC58 902233 NP_273184.1 CDS nusG NC_003112.2 133925 134461 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 133925..134461 Neisseria meningitidis MC58 902234 NP_273185.1 CDS rplK NC_003112.2 134562 134996 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 134562..134996 Neisseria meningitidis MC58 902235 NP_273186.1 CDS rplA NC_003112.2 134996 135691 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 134996..135691 Neisseria meningitidis MC58 902236 NP_273187.1 CDS NMB0129 NC_003112.2 135760 135903 D hypothetical protein 135760..135903 Neisseria meningitidis MC58 902237 NP_273188.1 CDS rplJ NC_003112.2 135921 136421 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 135921..136421 Neisseria meningitidis MC58 902238 NP_273189.1 CDS rplL NC_003112.2 136479 136850 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 136479..136850 Neisseria meningitidis MC58 902239 NP_273190.1 CDS rpoB NC_003112.2 137034 141218 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 137034..141218 Neisseria meningitidis MC58 902240 NP_273191.1 CDS rpoC NC_003112.2 141375 145550 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 141375..145550 Neisseria meningitidis MC58 902241 NP_273192.1 CDS NMB0134 NC_003112.2 145842 146099 D hypothetical protein 145842..146099 Neisseria meningitidis MC58 902242 NP_273193.1 CDS NMB0135 NC_003112.2 146096 146245 D identified by similarity to GP:3414689; match to protein family HMM PF04575; hypothetical protein 146096..146245 Neisseria meningitidis MC58 902243 NP_273194.1 CDS rpsL NC_003112.2 146424 146795 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 146424..146795 Neisseria meningitidis MC58 902244 NP_273195.1 CDS rpsG NC_003112.2 146913 147383 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 146913..147383 Neisseria meningitidis MC58 902245 NP_273196.1 CDS fusA NC_003112.2 147402 149507 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 147402..149507 Neisseria meningitidis MC58 902246 NP_273197.1 CDS tufA NC_003112.2 149593 150777 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 149593..150777 Neisseria meningitidis MC58 902247 NP_273198.1 CDS rpsJ NC_003112.2 150795 151106 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 150795..151106 Neisseria meningitidis MC58 902248 NP_273199.1 CDS NMB0141 NC_003112.2 151248 151613 D identified by similarity to GP:3901097; transposase, truncation 151248..151613 Neisseria meningitidis MC58 903207 NP_273200.1 CDS rplC NC_003112.2 151784 152428 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 151784..152428 Neisseria meningitidis MC58 902249 NP_273201.1 CDS rplD NC_003112.2 152428 153048 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 152428..153048 Neisseria meningitidis MC58 902250 NP_273202.1 CDS rplW NC_003112.2 153045 153359 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 153045..153359 Neisseria meningitidis MC58 902251 NP_273203.1 CDS rplB NC_003112.2 153365 154198 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 153365..154198 Neisseria meningitidis MC58 902252 NP_273204.1 CDS rpsS NC_003112.2 154205 154483 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 154205..154483 Neisseria meningitidis MC58 902253 NP_273205.1 CDS rplV NC_003112.2 154492 154821 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 154492..154821 Neisseria meningitidis MC58 902254 NP_273206.1 CDS rpsC NC_003112.2 154831 155523 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 154831..155523 Neisseria meningitidis MC58 902255 NP_273207.1 CDS rplP NC_003112.2 155507 155923 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 155507..155923 Neisseria meningitidis MC58 902256 NP_273208.1 CDS rpmC NC_003112.2 155923 156114 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 155923..156114 Neisseria meningitidis MC58 902257 NP_273209.1 CDS rpsQ NC_003112.2 156114 156377 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 156114..156377 Neisseria meningitidis MC58 902258 NP_273210.1 CDS rplN NC_003112.2 156599 156967 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 156599..156967 Neisseria meningitidis MC58 902259 NP_273211.1 CDS rplX NC_003112.2 156979 157302 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 156979..157302 Neisseria meningitidis MC58 902260 NP_273212.1 CDS rplE NC_003112.2 157312 157851 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 157312..157851 Neisseria meningitidis MC58 902261 NP_273213.1 CDS rpsN NC_003112.2 157854 158159 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 157854..158159 Neisseria meningitidis MC58 902262 NP_273214.1 CDS rpsH NC_003112.2 158175 158567 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 158175..158567 Neisseria meningitidis MC58 902263 NP_273215.1 CDS rplF NC_003112.2 158581 159114 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 158581..159114 Neisseria meningitidis MC58 902264 NP_273216.1 CDS rplR NC_003112.2 159128 159481 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 159128..159481 Neisseria meningitidis MC58 902265 NP_273217.1 CDS rpsE NC_003112.2 159500 160018 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 159500..160018 Neisseria meningitidis MC58 902266 NP_273218.1 CDS rpmD NC_003112.2 160011 160196 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 160011..160196 Neisseria meningitidis MC58 902267 NP_273219.1 CDS rplO NC_003112.2 160198 160632 D late assembly protein; 50S ribosomal protein L15 160198..160632 Neisseria meningitidis MC58 902268 NP_273220.1 CDS secY NC_003112.2 160644 161954 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 160644..161954 Neisseria meningitidis MC58 902269 NP_273221.1 CDS infA NC_003112.2 161959 162177 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 161959..162177 Neisseria meningitidis MC58 902270 NP_273222.1 CDS rpmJ NC_003112.2 162198 162311 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 162198..162311 Neisseria meningitidis MC58 902271 NP_273223.1 CDS rpsM NC_003112.2 162377 162739 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 162377..162739 Neisseria meningitidis MC58 902272 NP_273224.1 CDS rpsK NC_003112.2 162759 163154 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 162759..163154 Neisseria meningitidis MC58 902273 NP_273225.1 CDS rpsD NC_003112.2 163174 163794 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 163174..163794 Neisseria meningitidis MC58 902274 NP_273226.1 CDS rpoA NC_003112.2 163820 164806 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 163820..164806 Neisseria meningitidis MC58 902275 NP_273227.1 CDS rplQ NC_003112.2 164830 165198 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 164830..165198 Neisseria meningitidis MC58 902276 NP_273228.1 CDS minC NC_003112.2 165345 166058 D blocks the formation of polar Z-ring septums; septum formation inhibitor 165345..166058 Neisseria meningitidis MC58 902277 NP_273229.1 CDS minD NC_003112.2 166086 166901 D identified by similarity to EGAD:13527; match to protein family HMM PF01656; match to protein family HMM TIGR01968; septum site-determining protein 166086..166901 Neisseria meningitidis MC58 902278 NP_273230.1 CDS minE NC_003112.2 166905 167168 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 166905..167168 Neisseria meningitidis MC58 902279 NP_273231.1 CDS NMB0173 NC_003112.2 167172 168092 D identified by similarity to EGAD:137604; match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 167172..168092 Neisseria meningitidis MC58 902280 NP_273232.1 CDS valS NC_003112.2 168422 171259 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(168422..171259) Neisseria meningitidis MC58 902281 NP_273233.1 CDS NMB0175 NC_003112.2 171356 172165 R identified by similarity to EGAD:21714; match to protein family HMM PF02535; zinc transporter ZupT complement(171356..172165) Neisseria meningitidis MC58 902282 NP_273234.1 CDS dadA NC_003112.2 172346 173602 R catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit complement(172346..173602) Neisseria meningitidis MC58 902283 NP_273235.1 CDS NMB0177 NC_003112.2 173681 175072 R identified by similarity to EGAD:90049; match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium/alanine symporter complement(173681..175072) Neisseria meningitidis MC58 902284 NP_273236.1 CDS lpxA NC_003112.2 175429 176205 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(175429..176205) Neisseria meningitidis MC58 902285 NP_273237.1 CDS fabZ NC_003112.2 176292 176741 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(176292..176741) Neisseria meningitidis MC58 902286 NP_273238.1 CDS lpxD NC_003112.2 176775 177821 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(176775..177821) Neisseria meningitidis MC58 902287 NP_273239.1 CDS NMB0181 NC_003112.2 177854 178354 R identified by similarity to EGAD:24192; match to protein family HMM PF03938; outer membrane protein OmpH complement(177854..178354) Neisseria meningitidis MC58 902288 NP_273240.1 CDS omp85 NC_003112.2 178420 180813 R identified by similarity to GP:2460281; match to protein family HMM PF01103; match to protein family HMM PF07244; outer membrane protein OMP85 complement(178420..180813) Neisseria meningitidis MC58 902289 NP_273241.1 CDS NMB0183 NC_003112.2 180870 182210 R identified by similarity to EGAD:8229; match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054; hypothetical protein complement(180870..182210) Neisseria meningitidis MC58 902290 NP_273242.1 CDS dxr NC_003112.2 182245 183429 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(182245..183429) Neisseria meningitidis MC58 902291 NP_273243.1 CDS cdsA NC_003112.2 183485 184282 R identified by similarity to EGAD:46780; match to protein family HMM PF01148; phosphatidate cytidylyltransferase complement(183485..184282) Neisseria meningitidis MC58 902292 NP_273244.1 CDS uppS NC_003112.2 184285 185031 R identified by similarity to EGAD:35926; match to protein family HMM PF01255; match to protein family HMM TIGR00055; undecaprenyl pyrophosphate synthetase complement(184285..185031) Neisseria meningitidis MC58 902293 NP_273245.1 CDS frr NC_003112.2 185087 185644 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(185087..185644) Neisseria meningitidis MC58 902294 NP_273246.1 CDS NMB0188 NC_003112.2 185824 186951 R identified by similarity to EGAD:9221; hypothetical protein complement(185824..186951) Neisseria meningitidis MC58 902295 NP_273248.1 CDS gidB NC_003112.2 187942 188565 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 187942..188565 Neisseria meningitidis MC58 902298 NP_273249.1 CDS NMB0191 NC_003112.2 188664 189437 D identified by similarity to EGAD:5746; match to protein family HMM PF01656; ParA family protein 188664..189437 Neisseria meningitidis MC58 902299 NP_273250.1 CDS rnhB NC_003112.2 190697 191281 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(190697..191281) Neisseria meningitidis MC58 902300 NP_273251.1 CDS gidA NC_003112.2 191350 193245 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(191350..193245) Neisseria meningitidis MC58 902301 NP_273252.1 CDS NMB0194 NC_003112.2 193571 194998 R identified by similarity to EGAD:28821; match to protein family HMM PF01235; match to protein family HMM TIGR00835; amino acid symporter complement(193571..194998) Neisseria meningitidis MC58 902302 NP_273253.1 CDS pdxA NC_003112.2 195140 196147 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 195140..196147 Neisseria meningitidis MC58 902303 NP_273254.1 CDS rne NC_003112.2 197445 200204 R identified by similarity to GP:49116; match to protein family HMM PF00575; match to protein family HMM TIGR00757; ribonuclease E complement(197445..200204) Neisseria meningitidis MC58 902304 NP_273256.1 CDS rluC NC_003112.2 200697 201689 D identified by similarity to EGAD:7861; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase C 200697..201689 Neisseria meningitidis MC58 902306 NP_273257.1 CDS lpxB NC_003112.2 201737 202909 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 201737..202909 Neisseria meningitidis MC58 902307 NP_273258.1 CDS NMB0200 NC_003112.2 203119 203508 R hypothetical protein complement(203119..203508) Neisseria meningitidis MC58 902308 NP_273259.1 CDS NMB0201 NC_003112.2 203731 204141 D hypothetical protein 203731..204141 Neisseria meningitidis MC58 902309 NP_273261.1 CDS dapB NC_003112.2 204405 205214 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(204405..205214) Neisseria meningitidis MC58 902311 NP_273262.1 CDS NMB0204 NC_003112.2 205224 205601 R identified by similarity to SP:P23089; match to protein family HMM PF04355; lipoprotein complement(205224..205601) Neisseria meningitidis MC58 902312 NP_273263.1 CDS fur NC_003112.2 205820 206254 D identified by similarity to EGAD:14408; match to protein family HMM PF01475; ferric uptake regulation protein 205820..206254 Neisseria meningitidis MC58 902313 NP_273264.1 CDS aat NC_003112.2 206324 207049 D leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 206324..207049 Neisseria meningitidis MC58 902314 NP_273265.1 CDS gapA-1 NC_003112.2 207302 208333 R catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase complement(207302..208333) Neisseria meningitidis MC58 902315 NP_273266.1 CDS NMB0208 NC_003112.2 208532 209371 R identified by similarity to EGAD:90639; match to protein family HMM PF00037; match to protein family HMM PF04060; match to protein family HMM TIGR01944; ferredoxin, 4Fe-4S type complement(208532..209371) Neisseria meningitidis MC58 902316 NP_273267.1 CDS kefB NC_003112.2 209520 211496 D identified by similarity to EGAD:29394; match to protein family HMM PF02080; match to protein family HMM PF02254; glutathione-regulated potassium-efflux system protein 209520..211496 Neisseria meningitidis MC58 902317 NP_273268.1 CDS sdaA NC_003112.2 212715 214100 R identified by similarity to GP:3402236; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase complement(212715..214100) Neisseria meningitidis MC58 902323 NP_273269.1 CDS gyrB NC_003112.2 214197 216587 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(214197..216587) Neisseria meningitidis MC58 902324 NP_273270.1 CDS NMB0213 NC_003112.2 216743 217729 D hypothetical protein 216743..217729 Neisseria meningitidis MC58 902325 NP_273271.1 CDS prlC NC_003112.2 217817 219853 D identified by similarity to EGAD:28851; match to protein family HMM PF01432; oligopeptidase A 217817..219853 Neisseria meningitidis MC58 902326 NP_273272.1 CDS NMB0215 NC_003112.2 220476 221042 R identified by similarity to EGAD:32789; match to protein family HMM PF02659; hypothetical protein complement(220476..221042) Neisseria meningitidis MC58 902327 NP_273273.1 CDS kat NC_003112.2 221438 222952 R identified by similarity to EGAD:21555; match to protein family HMM PF00199; catalase complement(221438..222952) Neisseria meningitidis MC58 902328 NP_273274.1 CDS NMB0217 NC_003112.2 223300 224151 D identified by similarity to EGAD:7711; match to protein family HMM PF00309; match to protein family HMM PF04552; match to protein family HMM PF04963; RNA polymerase sigma-54 factor RpoN 223300..224151 Neisseria meningitidis MC58 902329 NP_273275.1 CDS pglA NC_003112.2 225071 226201 R identified by similarity to GP:3599932; match to protein family HMM PF00534; glycosyltransferase complement(225071..226201) Neisseria meningitidis MC58 902330 NP_273276.1 CDS fabF-1 NC_003112.2 226506 227753 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(226506..227753) Neisseria meningitidis MC58 902331 NP_273277.1 CDS acpP NC_003112.2 227909 228145 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(227909..228145) Neisseria meningitidis MC58 902332 NP_273278.1 CDS pyrD NC_003112.2 228377 229384 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 228377..229384 Neisseria meningitidis MC58 902333 NP_273279.1 CDS NMB0222 NC_003112.2 229547 230020 D hypothetical protein 229547..230020 Neisseria meningitidis MC58 902334 NP_273281.1 CDS glnE NC_003112.2 230563 233253 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 230563..233253 Neisseria meningitidis MC58 902336 NP_273282.1 CDS NMB0225 NC_003112.2 233555 234520 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(233555..234520) Neisseria meningitidis MC58 902337 NP_273283.1 CDS NMB0226 NC_003112.2 234785 235477 R identified by similarity to EGAD:106326; match to protein family HMM PF01863; hypothetical protein complement(234785..235477) Neisseria meningitidis MC58 902338 NP_273284.1 CDS NMB0227 NC_003112.2 235585 236778 R identified by similarity to EGAD:28718; hypothetical protein complement(235585..236778) Neisseria meningitidis MC58 902339 NP_273285.1 CDS NMB0228 NC_003112.2 236907 237644 R identified by similarity to EGAD:28719; match to protein family HMM PF03746; LamB/YcsF family protein complement(236907..237644) Neisseria meningitidis MC58 902340 NP_273287.1 CDS NMB0230 NC_003112.2 238556 239203 R identified by similarity to EGAD:28721; match to protein family HMM PF02682; match to protein family HMM TIGR00370; hypothetical protein complement(238556..239203) Neisseria meningitidis MC58 902341 NP_273288.1 CDS NMB0231 NC_003112.2 239259 239363 R hypothetical protein complement(239259..239363) Neisseria meningitidis MC58 902342 NP_273289.1 CDS uvrD NC_003112.2 239387 241594 D identified by similarity to EGAD:14237; match to protein family HMM PF00580; match to protein family HMM TIGR01075; DNA helicase II 239387..241594 Neisseria meningitidis MC58 902343 NP_273290.1 CDS NMB0233 NC_003112.2 241670 241771 D hypothetical protein 241670..241771 Neisseria meningitidis MC58 902344 NP_273291.1 CDS NMB0234 NC_003112.2 242118 242657 D hypothetical protein 242118..242657 Neisseria meningitidis MC58 902345 NP_273294.1 CDS NMB0237 NC_003112.2 243183 243542 R hypothetical protein complement(243183..243542) Neisseria meningitidis MC58 902348 NP_273295.1 CDS NMB0239 NC_003112.2 244058 244678 D hypothetical protein 244058..244678 Neisseria meningitidis MC58 902350 NP_273296.1 CDS NMB0240 NC_003112.2 244701 246152 D hypothetical protein 244701..246152 Neisseria meningitidis MC58 902351 NP_273297.1 CDS nuoA NC_003112.2 246614 246970 D identified by similarity to GP:3025801; match to protein family HMM PF00507; NADH dehydrogenase I subunit A 246614..246970 Neisseria meningitidis MC58 902352 NP_273298.1 CDS nuoB NC_003112.2 246961 247443 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 246961..247443 Neisseria meningitidis MC58 902353 NP_273299.1 CDS nuoC NC_003112.2 247456 248049 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 247456..248049 Neisseria meningitidis MC58 902354 NP_273300.1 CDS nuoD NC_003112.2 248039 249295 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 248039..249295 Neisseria meningitidis MC58 902355 NP_273301.1 CDS nuoE NC_003112.2 249295 249768 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 249295..249768 Neisseria meningitidis MC58 902356 NP_273302.1 CDS nuoF NC_003112.2 250158 251459 D identified by similarity to EGAD:102346; match to protein family HMM PF01512; match to protein family HMM TIGR01959; NADH dehydrogenase I subunit F 250158..251459 Neisseria meningitidis MC58 902357 NP_273303.1 CDS NMB0247 NC_003112.2 251459 251896 D hypothetical protein 251459..251896 Neisseria meningitidis MC58 902358 NP_273304.1 CDS NMB0248 NC_003112.2 252182 252421 D identified by similarity to GP:2570056; match to protein family HMM PF01541; hypothetical protein 252182..252421 Neisseria meningitidis MC58 902359 NP_273305.1 CDS nuoG NC_003112.2 252733 254994 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 252733..254994 Neisseria meningitidis MC58 902360 NP_273306.1 CDS nuoH NC_003112.2 254997 256073 D identified by similarity to EGAD:96512; match to protein family HMM PF00146; NADH dehydrogenase I subunit H 254997..256073 Neisseria meningitidis MC58 902361 NP_273307.1 CDS nuoI NC_003112.2 256154 256633 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 256154..256633 Neisseria meningitidis MC58 902362 NP_273308.1 CDS NMB0252 NC_003112.2 256664 257371 D hypothetical protein 256664..257371 Neisseria meningitidis MC58 902363 NP_273309.1 CDS nuoJ NC_003112.2 257407 258078 D identified by similarity to EGAD:42978; match to protein family HMM PF00499; NADH dehydrogenase I subunit J 257407..258078 Neisseria meningitidis MC58 902364 NP_273310.1 CDS nuoK NC_003112.2 258075 258380 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 258075..258380 Neisseria meningitidis MC58 902365 NP_273311.1 CDS NMB0255 NC_003112.2 258414 258989 D identified by similarity to EGAD:27990; match to protein family HMM PF02661; cell filamentation protein Fic-like protein 258414..258989 Neisseria meningitidis MC58 902366 NP_273312.1 CDS NMB0256 NC_003112.2 259113 259454 D hypothetical protein 259113..259454 Neisseria meningitidis MC58 902367 NP_273313.1 CDS nuoL NC_003112.2 259503 261527 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 259503..261527 Neisseria meningitidis MC58 902368 NP_273314.1 CDS nuoM NC_003112.2 261623 263119 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 261623..263119 Neisseria meningitidis MC58 902369 NP_273315.1 CDS nuoN NC_003112.2 263129 264571 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 263129..264571 Neisseria meningitidis MC58 902370 NP_273317.1 CDS ispA NC_003112.2 265091 265870 R identified by similarity to EGAD:28427; match to protein family HMM PF00348; geranyltranstransferase complement(265091..265870) Neisseria meningitidis MC58 902372 NP_273318.1 CDS xseB NC_003112.2 265971 266195 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(265971..266195) Neisseria meningitidis MC58 902373 NP_273319.1 CDS NMB0263 NC_003112.2 266442 267365 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(266442..267365) Neisseria meningitidis MC58 902374 NP_273320.1 CDS NMB0264 NC_003112.2 267370 269226 R identified by similarity to EGAD:28073; match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein complement(267370..269226) Neisseria meningitidis MC58 902375 NP_273321.1 CDS ruvA NC_003112.2 269389 269973 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(269389..269973) Neisseria meningitidis MC58 902376 NP_273322.1 CDS NMB0266 NC_003112.2 270055 270381 R identified by similarity to EGAD:107494; match to protein family HMM PF03413; hypothetical protein complement(270055..270381) Neisseria meningitidis MC58 902377 NP_273323.1 CDS NMB0267 NC_003112.2 270443 271162 R identified by similarity to EGAD:27846; match to protein family HMM PF03330; match to protein family HMM TIGR00413; hypothetical protein complement(270443..271162) Neisseria meningitidis MC58 902378 NP_273324.1 CDS NMB0268 NC_003112.2 271292 271756 R identified by similarity to EGAD:8165; match to protein family HMM PF00588; match to protein family HMM TIGR00185; RNA methyltransferase complement(271292..271756) Neisseria meningitidis MC58 902379 NP_273325.1 CDS NMB0269 NC_003112.2 271821 272546 R identified by similarity to EGAD:18112; competence protein complement(271821..272546) Neisseria meningitidis MC58 902380 NP_273326.1 CDS NMB0270 NC_003112.2 272545 273294 D identified by similarity to EGAD:8656; match to protein family HMM PF00561; match to protein family HMM TIGR01738; bioH protein 272545..273294 Neisseria meningitidis MC58 902381 NP_273327.1 CDS NMB0271 NC_003112.2 273291 274079 D hypothetical protein 273291..274079 Neisseria meningitidis MC58 902382 NP_273329.1 CDS NMB0273 NC_003112.2 274868 275293 D hypothetical protein 274868..275293 Neisseria meningitidis MC58 902384 NP_273330.1 CDS recQ NC_003112.2 275435 277735 R identified by similarity to GP:148221; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389; ATP-dependent DNA helicase complement(275435..277735) Neisseria meningitidis MC58 902385 NP_273331.1 CDS trpC NC_003112.2 277800 278582 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase complement(277800..278582) Neisseria meningitidis MC58 902386 NP_273332.1 CDS NMB0276 NC_003112.2 278633 279589 R identified by similarity to EGAD:101623; hypothetical protein complement(278633..279589) Neisseria meningitidis MC58 902387 NP_273333.1 CDS mviN NC_003112.2 279721 281262 R identified by similarity to EGAD:90808; match to protein family HMM PF03023; match to protein family HMM TIGR01695; virulence factor MviN complement(279721..281262) Neisseria meningitidis MC58 902388 NP_273334.1 CDS dsbA-1 NC_003112.2 281477 282175 D identified by similarity to EGAD:98963; match to protein family HMM PF01323; thiol:disulfide interchange protein DsbA 281477..282175 Neisseria meningitidis MC58 902389 NP_273335.1 CDS NMB0279 NC_003112.2 282232 283236 R identified by similarity to EGAD:137413; hypothetical protein complement(282232..283236) Neisseria meningitidis MC58 902390 NP_273336.1 CDS NMB0280 NC_003112.2 283438 285714 D identified by similarity to EGAD:7471; match to protein family HMM PF04453; organic solvent tolerance protein 283438..285714 Neisseria meningitidis MC58 902391 NP_273337.1 CDS NMB0281 NC_003112.2 285816 286862 D identified by similarity to EGAD:7686; match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase 285816..286862 Neisseria meningitidis MC58 902392 NP_273338.1 CDS NMB0282 NC_003112.2 288370 290250 R identified by similarity to EGAD:28723; match to protein family HMM PF00773; ribonuclease II-related protein complement(288370..290250) Neisseria meningitidis MC58 902393 NP_273339.1 CDS NMB0283 NC_003112.2 290559 291191 D identified by similarity to EGAD:155656; match to protein family HMM PF03641; match to protein family HMM TIGR00730; hypothetical protein 290559..291191 Neisseria meningitidis MC58 902394 NP_273340.1 CDS purB NC_003112.2 291263 292633 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 291263..292633 Neisseria meningitidis MC58 902395 NP_273341.1 CDS NMB0286 NC_003112.2 294874 295488 R identified by similarity to EGAD:5824; match to protein family HMM PF04391; hypothetical protein complement(294874..295488) Neisseria meningitidis MC58 902397 NP_273342.1 CDS dinG NC_003112.2 295525 297675 R helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG complement(295525..297675) Neisseria meningitidis MC58 902398 NP_273344.1 CDS NMB0290 NC_003112.2 299360 300271 R identified by similarity to GP:1139588; match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator complement(299360..300271) Neisseria meningitidis MC58 902401 NP_273345.1 CDS NMB0291 NC_003112.2 300379 300777 D identified by similarity to EGAD:160719; match to protein family HMM PF07681; hypothetical protein 300379..300777 Neisseria meningitidis MC58 902402 NP_273346.1 CDS NMB0292 NC_003112.2 300826 301431 D identified by similarity to EGAD:51135; hypothetical protein 300826..301431 Neisseria meningitidis MC58 902403 NP_273347.1 CDS NMB0293 NC_003112.2 301617 303728 D identified by similarity to EGAD:48295; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; TonB-dependent receptor 301617..303728 Neisseria meningitidis MC58 902404 NP_273348.1 CDS dsbA-2 NC_003112.2 303843 304538 D identified by similarity to GP:2707768; match to protein family HMM PF01323; thiol:disulfide interchange protein DsbA 303843..304538 Neisseria meningitidis MC58 902405 NP_273349.1 CDS ffh NC_003112.2 304869 306239 R identified by similarity to EGAD:6526; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein complement(304869..306239) Neisseria meningitidis MC58 902406 NP_273350.1 CDS NMB0296 NC_003112.2 306459 307265 D identified by similarity to GP:706856; match to protein family HMM PF01578; CcsA-like protein 306459..307265 Neisseria meningitidis MC58 902407 NP_273351.1 CDS NMB0297 NC_003112.2 307279 307377 D hypothetical protein 307279..307377 Neisseria meningitidis MC58 902408 NP_273353.1 CDS NMB0299 NC_003112.2 313104 313550 D identified by similarity to EGAD:36757; match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259; comEA-related protein 313104..313550 Neisseria meningitidis MC58 902415 YP_008920704.1 CDS NMB0302 NC_003112.2 314275 314943 D transposase 314275..314943 Neisseria meningitidis MC58 902418 NP_273357.1 CDS aroG NC_003112.2 316410 317465 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 316410..317465 Neisseria meningitidis MC58 902423 NP_273358.1 CDS folA NC_003112.2 317533 318021 D identified by similarity to EGAD:8105; match to protein family HMM PF00186; dihydrofolate reductase 317533..318021 Neisseria meningitidis MC58 902424 NP_273359.1 CDS NMB0309 NC_003112.2 318371 318847 R identified by similarity to EGAD:49208; match to protein family HMM PF01928; hypothetical protein complement(318371..318847) Neisseria meningitidis MC58 902425 NP_273360.1 CDS NMB0310 NC_003112.2 318859 319287 R identified by similarity to EGAD:89978; match to protein family HMM PF03653; hypothetical protein complement(318859..319287) Neisseria meningitidis MC58 902426 NP_273361.1 CDS NMB0311 NC_003112.2 319399 319644 D hypothetical protein 319399..319644 Neisseria meningitidis MC58 902427 YP_008920705.1 CDS vapA NC_003112.2 321328 323187 D ATPase 321328..323187 Neisseria meningitidis MC58 902428 NP_273362.1 CDS NMB0313 NC_003112.2 323429 324895 D identified by similarity to GP:3523136; match to protein family HMM PF04575; match to protein family HMM PF07719; hypothetical protein 323429..324895 Neisseria meningitidis MC58 902429 NP_273363.1 CDS NMB0314 NC_003112.2 325096 326064 R hypothetical protein complement(325096..326064) Neisseria meningitidis MC58 902430 NP_273364.1 CDS NMB0315 NC_003112.2 326142 327434 D identified by similarity to GP:146890; match to protein family HMM PF01551; hypothetical protein 326142..327434 Neisseria meningitidis MC58 902431 NP_273365.1 CDS NMB0316 NC_003112.2 327937 328623 R identified by similarity to EGAD:8792; match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein complement(327937..328623) Neisseria meningitidis MC58 902432 NP_273366.1 CDS NMB0317 NC_003112.2 328698 329171 R NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(328698..329171) Neisseria meningitidis MC58 902433 NP_273367.1 CDS farA NC_003112.2 329613 330767 D identified by similarity to EGAD:20365; match to protein family HMM PF00529; fatty acid efflux system protein 329613..330767 Neisseria meningitidis MC58 902434 NP_273368.1 CDS farB NC_003112.2 330791 332317 D identified by similarity to EGAD:19655; match to protein family HMM PF07690; match to protein family HMM TIGR00711; fatty acid efflux system protein 330791..332317 Neisseria meningitidis MC58 902435 NP_273370.1 CDS rpmB NC_003112.2 332567 332800 D required for 70S ribosome assembly; 50S ribosomal protein L28 332567..332800 Neisseria meningitidis MC58 902437 NP_273371.1 CDS rpmG NC_003112.2 332832 332987 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 332832..332987 Neisseria meningitidis MC58 902438 NP_273372.1 CDS NMB0323 NC_003112.2 333176 334360 R identified by similarity to EGAD:19694; match to protein family HMM PF01360; match to protein family HMM TIGR01988; hypothetical protein complement(333176..334360) Neisseria meningitidis MC58 902439 NP_273373.1 CDS rpmA NC_003112.2 334699 334971 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(334699..334971) Neisseria meningitidis MC58 902440 NP_273374.1 CDS rplU NC_003112.2 334996 335304 R identified by similarity to EGAD:23167; match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 complement(334996..335304) Neisseria meningitidis MC58 902441 NP_273375.1 CDS ispB NC_003112.2 335528 336502 D identified by similarity to EGAD:8604; match to protein family HMM PF00348; octaprenyl-diphosphate synthase 335528..336502 Neisseria meningitidis MC58 902442 NP_273377.1 CDS NMB0328 NC_003112.2 337073 337177 D hypothetical protein 337073..337177 Neisseria meningitidis MC58 902444 NP_273378.1 CDS pilF NC_003112.2 337395 339071 D identified by similarity to EGAD:21691; match to protein family HMM PF00437; match to protein family HMM PF05157; match to protein family HMM TIGR02538; type IV pilus assembly protein 337395..339071 Neisseria meningitidis MC58 902445 NP_273379.1 CDS NMB0330 NC_003112.2 339156 339365 R identified by similarity to EGAD:36778; match to protein family HMM PF03884; hypothetical protein complement(339156..339365) Neisseria meningitidis MC58 902446 NP_273380.1 CDS NMB0331 NC_003112.2 339358 339990 R identified by similarity to EGAD:40831; match to protein family HMM PF01121; match to protein family HMM TIGR00152; kinase complement(339358..339990) Neisseria meningitidis MC58 903204 NP_273381.1 CDS pilD NC_003112.2 339992 340852 R identified by similarity to EGAD:40757; match to protein family HMM PF01478; match to protein family HMM PF06750; type IV prepilin peptidase complement(339992..340852) Neisseria meningitidis MC58 902447 NP_273382.1 CDS pilG NC_003112.2 340926 342158 R identified by similarity to EGAD:40687; match to protein family HMM PF00482; pilus assembly protein PilG complement(340926..342158) Neisseria meningitidis MC58 902448 NP_273383.1 CDS pgi NC_003112.2 342515 344158 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 342515..344158 Neisseria meningitidis MC58 902449 NP_273384.1 CDS dapD NC_003112.2 344368 345189 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 344368..345189 Neisseria meningitidis MC58 902450 NP_273385.1 CDS fabI NC_003112.2 345344 346129 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 345344..346129 Neisseria meningitidis MC58 902451 NP_273386.1 CDS NMB0337 NC_003112.2 346373 347371 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(346373..347371) Neisseria meningitidis MC58 902452 NP_273387.2 CDS NMB0338 NC_003112.2 347639 347995 D hypothetical protein 347639..347995 Neisseria meningitidis MC58 902453 NP_273388.1 CDS NMB0339 NC_003112.2 348006 349175 D identified by similarity to EGAD:28234; tetratricopeptide repeat protein 348006..349175 Neisseria meningitidis MC58 902454 NP_273389.1 CDS gloA NC_003112.2 349200 349616 D identified by similarity to EGAD:134180; match to protein family HMM PF00903; match to protein family HMM TIGR00068; lactoylglutathione lyase 349200..349616 Neisseria meningitidis MC58 902455 NP_273390.1 CDS NMB0341 NC_003112.2 349788 352415 R identified by similarity to GP:3413497; match to protein family HMM PF01476; tspA protein complement(349788..352415) Neisseria meningitidis MC58 902456 NP_273391.1 CDS ispZ NC_003112.2 352621 353151 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 352621..353151 Neisseria meningitidis MC58 902457 NP_273392.1 CDS NMB0343 NC_003112.2 353166 353444 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 353166..353444 Neisseria meningitidis MC58 902458 NP_273393.1 CDS NMB0344 NC_003112.2 353444 353722 D identified by similarity to EGAD:21163; match to protein family HMM PF01722; BolA/YrbA family protein 353444..353722 Neisseria meningitidis MC58 902459 NP_273394.1 CDS NMB0345 NC_003112.2 353771 354637 D identified by similarity to EGAD:12394; cell-binding factor 353771..354637 Neisseria meningitidis MC58 902460 NP_273395.1 CDS NMB0346 NC_003112.2 354708 355466 D hypothetical protein 354708..355466 Neisseria meningitidis MC58 902461 NP_273396.1 CDS NMB0347 NC_003112.2 355539 356030 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 355539..356030 Neisseria meningitidis MC58 902462 NP_273397.1 CDS NMB0348 NC_003112.2 356061 357071 D identified by similarity to EGAD:6786; match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 356061..357071 Neisseria meningitidis MC58 902463 NP_273398.1 CDS NMB0349 NC_003112.2 357141 358028 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(357141..358028) Neisseria meningitidis MC58 902464 NP_273399.2 CDS NMB0350 NC_003112.2 358316 358675 R hypothetical protein complement(358316..358675) Neisseria meningitidis MC58 902465 NP_273400.1 CDS tal NC_003112.2 358919 359974 R catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase complement(358919..359974) Neisseria meningitidis MC58 902466 NP_273401.1 CDS NMB0352 NC_003112.2 360071 361045 D identified by similarity to EGAD:29719; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; KpsF/GutQ family sugar isomerase 360071..361045 Neisseria meningitidis MC58 902467 NP_273402.1 CDS NMB0353 NC_003112.2 361263 361799 D identified by similarity to EGAD:155354; match to protein family HMM TIGR01662; match to protein family HMM TIGR01670; hypothetical protein 361263..361799 Neisseria meningitidis MC58 902468 NP_273403.1 CDS NMB0354 NC_003112.2 361796 362377 D hypothetical protein 361796..362377 Neisseria meningitidis MC58 902469 NP_273404.1 CDS NMB0355 NC_003112.2 362358 362888 D identified by similarity to EGAD:28154; match to protein family HMM PF03968; hypothetical protein 362358..362888 Neisseria meningitidis MC58 902470 NP_273405.1 CDS NMB0356 NC_003112.2 362932 363696 D identified by similarity to EGAD:139998; match to protein family HMM PF00005; ABC transporter ATP-binding protein 362932..363696 Neisseria meningitidis MC58 902471 NP_273406.1 CDS mtgA NC_003112.2 364165 364866 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(364165..364866) Neisseria meningitidis MC58 902473 NP_273407.1 CDS aroE NC_003112.2 364869 365678 R identified by similarity to EGAD:142367; match to protein family HMM PF01488; match to protein family HMM TIGR00507; shikimate dehydrogenase complement(364869..365678) Neisseria meningitidis MC58 902474 NP_273408.1 CDS glnA NC_003112.2 365978 367396 D identified by similarity to EGAD:130497; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase 365978..367396 Neisseria meningitidis MC58 902475 NP_273409.1 CDS NMB0360 NC_003112.2 367552 368835 D identified by similarity to EGAD:147104; match to protein family HMM PF07690; match to protein family HMM TIGR00901; AmpG-like protein 367552..368835 Neisseria meningitidis MC58 902476 NP_273410.1 CDS NMB0361 NC_003112.2 368832 369107 D identified by similarity to EGAD:147105; match to protein family HMM PF01541; hypothetical protein 368832..369107 Neisseria meningitidis MC58 902477 NP_273411.1 CDS NMB0362 NC_003112.2 369213 369293 D hypothetical protein 369213..369293 Neisseria meningitidis MC58 902478 NP_273412.1 CDS NMB0363 NC_003112.2 369618 369755 D hypothetical protein 369618..369755 Neisseria meningitidis MC58 902479 NP_273413.1 CDS NMB0364 NC_003112.2 370096 370869 D identified by similarity to EGAD:20116; match to protein family HMM PF06901; FrpC operon protein 370096..370869 Neisseria meningitidis MC58 902480 NP_273414.1 CDS NMB0365 NC_003112.2 370886 371161 D identified by similarity to EGAD:18289; iron-regulated protein FrpC, truncation 370886..371161 Neisseria meningitidis MC58 903203 NP_273415.1 CDS NMB0366 NC_003112.2 371248 372381 R hypothetical protein complement(371248..372381) Neisseria meningitidis MC58 902481 NP_273416.1 CDS NMB0367 NC_003112.2 372445 372831 R hypothetical protein complement(372445..372831) Neisseria meningitidis MC58 902482 NP_273417.1 CDS NMB0368 NC_003112.2 372900 373358 R hypothetical protein complement(372900..373358) Neisseria meningitidis MC58 902483 NP_273418.1 CDS NMB0369 NC_003112.2 373339 373728 R hypothetical protein complement(373339..373728) Neisseria meningitidis MC58 902484 NP_273419.1 CDS NMB0370 NC_003112.2 373860 374237 R hypothetical protein complement(373860..374237) Neisseria meningitidis MC58 902485 NP_273420.1 CDS NMB0371 NC_003112.2 374259 374666 R hypothetical protein complement(374259..374666) Neisseria meningitidis MC58 902486 NP_273421.1 CDS NMB0372 NC_003112.2 374672 375349 R hypothetical protein complement(374672..375349) Neisseria meningitidis MC58 902487 NP_273422.1 CDS NMB0373 NC_003112.2 375564 375923 R hypothetical protein complement(375564..375923) Neisseria meningitidis MC58 902488 NP_273423.1 CDS NMB0374 NC_003112.2 375926 377329 R identified by similarity to GP:4838555; match to protein family HMM PF06255; MafB-like protein complement(375926..377329) Neisseria meningitidis MC58 902489 NP_273424.1 CDS mafA-1 NC_003112.2 377333 378274 R identified by similarity to GP:4838554; mafA protein complement(377333..378274) Neisseria meningitidis MC58 902490 NP_273425.1 CDS NMB0376 NC_003112.2 378271 378387 R hypothetical protein complement(378271..378387) Neisseria meningitidis MC58 902491 NP_273426.1 CDS anmK NC_003112.2 378394 379524 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(378394..379524) Neisseria meningitidis MC58 902492 NP_273427.1 CDS NMB0378 NC_003112.2 379815 381389 D identified by similarity to EGAD:160513; match to protein family HMM PF01384; phosphate permease 379815..381389 Neisseria meningitidis MC58 902493 NP_273428.1 CDS hemN NC_003112.2 381742 383163 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(381742..383163) Neisseria meningitidis MC58 902494 NP_273429.1 CDS NMB0380 NC_003112.2 383368 384102 D identified by similarity to EGAD:41030; match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/FNR family transcriptional regulator 383368..384102 Neisseria meningitidis MC58 902495 NP_273430.1 CDS cysB NC_003112.2 384215 385165 R identified by similarity to EGAD:32791; match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator CysB-like protein complement(384215..385165) Neisseria meningitidis MC58 902496 NP_273431.1 CDS rmpM NC_003112.2 385529 386257 D identified by similarity to EGAD:10394; match to protein family HMM PF00691; outer membrane protein class 4 385529..386257 Neisseria meningitidis MC58 902497 NP_273434.1 CDS thiL NC_003112.2 387108 388064 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 387108..388064 Neisseria meningitidis MC58 902500 NP_273435.1 CDS pgpA NC_003112.2 388057 388542 D identified by similarity to EGAD:28303; match to protein family HMM PF04608; phosphatidylglycerophosphatase A 388057..388542 Neisseria meningitidis MC58 902501 NP_273436.1 CDS NMB0387 NC_003112.2 388602 390278 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(388602..390278) Neisseria meningitidis MC58 902502 NP_273437.1 CDS NMB0388 NC_003112.2 390665 392020 D identified by similarity to EGAD:62114; match to protein family HMM PF07690; sugar transporter 390665..392020 Neisseria meningitidis MC58 902503 NP_273438.1 CDS galM NC_003112.2 392024 393034 D identified by similarity to EGAD:7305; match to protein family HMM PF01263; aldose 1-epimerase 392024..393034 Neisseria meningitidis MC58 902504 NP_273439.1 CDS mapA NC_003112.2 393268 395526 D identified by similarity to GP:3724125; match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636; maltose phosphorylase 393268..395526 Neisseria meningitidis MC58 902505 NP_273440.1 CDS pgmB NC_003112.2 395539 396204 D identified by similarity to EGAD:125152; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009; beta-phosphoglucomutase 395539..396204 Neisseria meningitidis MC58 902506 NP_273441.1 CDS nadB NC_003112.2 396382 397890 R identified by similarity to EGAD:18907; match to protein family HMM PF00890; match to protein family HMM TIGR00551; L-aspartate oxidase complement(396382..397890) Neisseria meningitidis MC58 902507 NP_273442.1 CDS NMB0393 NC_003112.2 397939 398274 R identified by similarity to GP:3647360; match to protein family HMM PF00893; multidrug resistance protein complement(397939..398274) Neisseria meningitidis MC58 902508 NP_273443.1 CDS nadA NC_003112.2 398426 399538 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(398426..399538) Neisseria meningitidis MC58 902509 NP_273444.1 CDS NMB0395 NC_003112.2 399740 400678 D identified by similarity to EGAD:161074; hypothetical protein 399740..400678 Neisseria meningitidis MC58 902510 NP_273445.1 CDS nadC NC_003112.2 400896 401777 D identified by similarity to EGAD:42463; match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; nicotinate-nucleotide pyrophosphorylase 400896..401777 Neisseria meningitidis MC58 902511 NP_273446.1 CDS NMB0397 NC_003112.2 401805 402092 D hypothetical protein 401805..402092 Neisseria meningitidis MC58 902512 NP_273447.1 CDS NMB0398 NC_003112.2 402184 402465 D identified by similarity to EGAD:91779; match to protein family HMM PF01022; match to protein family HMM TIGR01199; ArsR family transcriptional regulator 402184..402465 Neisseria meningitidis MC58 902513 NP_273448.1 CDS xthA NC_003112.2 402525 403295 D identified by similarity to EGAD:104607; match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 402525..403295 Neisseria meningitidis MC58 902514 NP_273449.1 CDS NMB0400 NC_003112.2 404238 404810 D identified by similarity to GP:3005554; transposase, truncated 404238..404810 Neisseria meningitidis MC58 903202 NP_273450.1 CDS putA NC_003112.2 405844 409449 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(405844..409449) Neisseria meningitidis MC58 902515 NP_273451.1 CDS putP NC_003112.2 409698 411224 R identified by similarity to EGAD:13061; match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121; sodium/proline symporter complement(409698..411224) Neisseria meningitidis MC58 902516 NP_273452.1 CDS NMB0403 NC_003112.2 411560 411652 R hypothetical protein complement(411560..411652) Neisseria meningitidis MC58 902517 NP_273453.1 CDS NMB0404 NC_003112.2 411707 412027 D identified by similarity to EGAD:36570; match to protein family HMM PF04380; hypothetical protein 411707..412027 Neisseria meningitidis MC58 902518 NP_273454.1 CDS comM NC_003112.2 412041 413537 D identified by similarity to EGAD:28125; match to protein family HMM PF01078; match to protein family HMM TIGR00368; competence protein ComM 412041..413537 Neisseria meningitidis MC58 902519 NP_273455.1 CDS NMB0406 NC_003112.2 413637 414506 D identified by similarity to EGAD:40704; match to protein family HMM PF05036; match to protein family HMM TIGR02223; hypothetical protein 413637..414506 Neisseria meningitidis MC58 902520 NP_273456.1 CDS dsbA-3 NC_003112.2 414509 415153 D identified by similarity to EGAD:98963; match to protein family HMM PF01323; thiol:disulfide interchange protein DsbA 414509..415153 Neisseria meningitidis MC58 902521 NP_273457.1 CDS bacA NC_003112.2 415186 416007 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 415186..416007 Neisseria meningitidis MC58 902522 NP_273458.1 CDS NMB0409 NC_003112.2 416580 417791 R identified by similarity to EGAD:48967; match to protein family HMM PF02636; hypothetical protein complement(416580..417791) Neisseria meningitidis MC58 902525 NP_273459.1 CDS NMB0410 NC_003112.2 418070 418525 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 418070..418525 Neisseria meningitidis MC58 902526 NP_273460.1 CDS mraW NC_003112.2 418522 419508 D identified by similarity to EGAD:17026; match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 418522..419508 Neisseria meningitidis MC58 902527 NP_273461.1 CDS NMB0412 NC_003112.2 419499 419768 D identified by similarity to EGAD:7061; match to protein family HMM TIGR02209; cell division protein FtsL-related protein 419499..419768 Neisseria meningitidis MC58 902528 NP_273462.1 CDS penA NC_003112.2 419829 421574 D identified by similarity to EGAD:40734; match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 2 419829..421574 Neisseria meningitidis MC58 902529 NP_273463.1 CDS murE NC_003112.2 421599 423077 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 421599..423077 Neisseria meningitidis MC58 902530 NP_273464.1 CDS murF NC_003112.2 424872 426239 D identified by similarity to EGAD:28149; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01143; UDP-MurNAc-pentapeptide synthetase 424872..426239 Neisseria meningitidis MC58 902532 NP_273465.1 CDS NMB0417 NC_003112.2 426242 426418 D hypothetical protein 426242..426418 Neisseria meningitidis MC58 902533 NP_273466.1 CDS mraY NC_003112.2 426665 427747 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 426665..427747 Neisseria meningitidis MC58 902534 NP_273467.1 CDS NMB0419 NC_003112.2 427873 428469 D identified by similarity to EGAD:91374; match to protein family HMM PF03937; hypothetical protein 427873..428469 Neisseria meningitidis MC58 902535 NP_273468.1 CDS murD NC_003112.2 428553 429890 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 428553..429890 Neisseria meningitidis MC58 902536 NP_273469.1 CDS ftsW NC_003112.2 430070 431341 D identified by similarity to EGAD:28142; match to protein family HMM PF01098; cell division protein 430070..431341 Neisseria meningitidis MC58 902537 NP_273470.1 CDS murG NC_003112.2 431345 432412 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 431345..432412 Neisseria meningitidis MC58 902538 NP_273471.2 CDS murC NC_003112.2 432570 433976 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 432570..433976 Neisseria meningitidis MC58 902539 NP_273472.1 CDS ddl NC_003112.2 434089 435003 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 434089..435003 Neisseria meningitidis MC58 902540 NP_273473.1 CDS ftsQ NC_003112.2 435014 435721 D identified by similarity to EGAD:21305; match to protein family HMM PF03799; cell division protein 435014..435721 Neisseria meningitidis MC58 902541 NP_273474.1 CDS ftsA NC_003112.2 435807 437051 D identified by similarity to GP:2707899; match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein 435807..437051 Neisseria meningitidis MC58 902542 NP_273475.1 CDS ftsZ NC_003112.2 437170 438348 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 437170..438348 Neisseria meningitidis MC58 902543 NP_273476.1 CDS NMB0428 NC_003112.2 438487 439797 D identified by similarity to EGAD:44500; match to protein family HMM PF00860; hypothetical protein 438487..439797 Neisseria meningitidis MC58 902544 NP_273477.1 CDS NMB0429 NC_003112.2 440170 440274 D hypothetical protein 440170..440274 Neisseria meningitidis MC58 902545 NP_273478.1 CDS prpB NC_003112.2 440420 441298 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 440420..441298 Neisseria meningitidis MC58 902546 NP_273479.1 CDS pprC NC_003112.2 441384 442538 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 441384..442538 Neisseria meningitidis MC58 902547 NP_273480.1 CDS NMB0432 NC_003112.2 442691 443479 D identified by similarity to EGAD:24560; match to protein family HMM PF01925; hypothetical protein 442691..443479 Neisseria meningitidis MC58 902548 NP_273481.1 CDS acnA NC_003112.2 443557 446163 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 443557..446163 Neisseria meningitidis MC58 902549 NP_273482.1 CDS NMB0434 NC_003112.2 446966 448135 D identified by similarity to EGAD:91576; match to protein family HMM PF04303; match to protein family HMM TIGR02334; AcnD-accessory protein PrpF 446966..448135 Neisseria meningitidis MC58 902550 NP_273483.1 CDS ackA-1 NC_003112.2 448549 449748 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 448549..449748 Neisseria meningitidis MC58 902551 NP_273484.1 CDS NMB0436 NC_003112.2 450086 450727 D identified by similarity to EGAD:28201; match to protein family HMM PF01300; match to protein family HMM TIGR00057; hypothetical protein 450086..450727 Neisseria meningitidis MC58 902552 NP_273485.1 CDS NMB0437 NC_003112.2 450854 451297 R identified by similarity to EGAD:9130; match to protein family HMM PF02082; match to protein family HMM TIGR00738; hypothetical protein complement(450854..451297) Neisseria meningitidis MC58 902553 NP_273486.1 CDS NMB0438 NC_003112.2 451471 451839 D hypothetical protein 451471..451839 Neisseria meningitidis MC58 902554 NP_273487.1 CDS NMB0439 NC_003112.2 451884 453038 D identified by similarity to EGAD:148199; match to protein family HMM PF05940; hypothetical protein 451884..453038 Neisseria meningitidis MC58 902555 NP_273488.1 CDS NMB0440 NC_003112.2 453095 453967 R identified by similarity to EGAD:156224; match to protein family HMM PF02153; prephenate dehydrogenase complement(453095..453967) Neisseria meningitidis MC58 902556 NP_273489.1 CDS NMB0441 NC_003112.2 454052 454864 D identified by similarity to EGAD:47743; match to protein family HMM PF00795; nitrilase 454052..454864 Neisseria meningitidis MC58 902557 YP_008920706.1 CDS NMB0442 NC_003112.2 454893 455567 R opacity protein complement(454893..455567) Neisseria meningitidis MC58 902558 NP_273490.1 CDS NMB0443 NC_003112.2 456464 457429 D identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase 456464..457429 Neisseria meningitidis MC58 902559 NP_273491.1 CDS NMB0444 NC_003112.2 457987 458841 D identified by similarity to EGAD:107888; match to protein family HMM PF00892; hypothetical protein 457987..458841 Neisseria meningitidis MC58 902560 NP_273492.1 CDS NMB0445 NC_003112.2 459360 460592 D identified by similarity to EGAD:28252; match to protein family HMM PF07690; match to protein family HMM TIGR00710; bicyclomycin resistance protein 459360..460592 Neisseria meningitidis MC58 902561 NP_273493.1 CDS pheA NC_003112.2 460670 461758 D identified by similarity to GP:4105530; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807; chorismate mutase 460670..461758 Neisseria meningitidis MC58 902562 NP_273494.1 CDS recO NC_003112.2 461795 462586 D identified by similarity to EGAD:14344; match to protein family HMM PF02565; match to protein family HMM TIGR00613; DNA repair protein (recombination protein o) 461795..462586 Neisseria meningitidis MC58 902563 NP_273495.1 CDS pdxJ NC_003112.2 462610 463338 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 462610..463338 Neisseria meningitidis MC58 902564 NP_273498.1 CDS NMB0451 NC_003112.2 464432 465199 D hypothetical protein 464432..465199 Neisseria meningitidis MC58 902567 NP_273499.1 CDS acpS NC_003112.2 465399 465776 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 465399..465776 Neisseria meningitidis MC58 902568 NP_273500.1 CDS mutT NC_003112.2 465858 466667 D identified by similarity to EGAD:29393; match to protein family HMM PF00293; mutT protein 465858..466667 Neisseria meningitidis MC58 902569 NP_273501.1 CDS NMB0454 NC_003112.2 466660 467082 D hypothetical protein 466660..467082 Neisseria meningitidis MC58 902570 NP_273502.1 CDS NMB0455 NC_003112.2 467131 468273 D identified by similarity to EGAD:48783; match to protein family HMM PF01170; match to protein family HMM PF02926; hypothetical protein 467131..468273 Neisseria meningitidis MC58 902571 NP_273503.1 CDS amiC NC_003112.2 468331 469581 R identified by similarity to EGAD:36618; match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase complement(468331..469581) Neisseria meningitidis MC58 902572 NP_273504.1 CDS NMB0457 NC_003112.2 469578 470039 R identified by similarity to EGAD:8343; match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein complement(469578..470039) Neisseria meningitidis MC58 902573 NP_273505.1 CDS murI NC_003112.2 470241 471053 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 470241..471053 Neisseria meningitidis MC58 902574 NP_273506.1 CDS NMB0459 NC_003112.2 472101 473210 R identified by similarity to EGAD:156656; match to protein family HMM PF02661; hypothetical protein complement(472101..473210) Neisseria meningitidis MC58 902575 NP_273507.1 CDS tbp2 NC_003112.2 475581 477719 D identified by similarity to EGAD:40649; match to protein family HMM PF01298; transferrin-binding protein B 475581..477719 Neisseria meningitidis MC58 902576 NP_273508.1 CDS tbp1 NC_003112.2 477806 480553 D identified by similarity to EGAD:145507; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01776; match to protein family HMM TIGR01786; transferrin-binding protein 1 477806..480553 Neisseria meningitidis MC58 902577 NP_273509.1 CDS potD-1 NC_003112.2 481824 483203 R identified by similarity to EGAD:21832; match to protein family HMM PF01547; spermidine/putrescine ABC transporter substrate-binding protein complement(481824..483203) Neisseria meningitidis MC58 902578 NP_273510.1 CDS rpsT NC_003112.2 483269 483532 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 483269..483532 Neisseria meningitidis MC58 902579 NP_273511.1 CDS NMB0464 NC_003112.2 483693 484841 D identified by similarity to EGAD:20225; match to protein family HMM PF02253; phospholipase A1 483693..484841 Neisseria meningitidis MC58 902580 NP_273512.1 CDS NMB0465 NC_003112.2 484984 485685 D identified by similarity to EGAD:163702; match to protein family HMM PF04367; hypothetical protein 484984..485685 Neisseria meningitidis MC58 902581 NP_273513.1 CDS aspS NC_003112.2 485743 487551 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 485743..487551 Neisseria meningitidis MC58 902582 NP_273514.1 CDS NMB0467 NC_003112.2 487702 487986 D hypothetical protein 487702..487986 Neisseria meningitidis MC58 902583 NP_273515.1 CDS speA NC_003112.2 488153 490045 D catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 488153..490045 Neisseria meningitidis MC58 902584 NP_273516.1 CDS speE NC_003112.2 490144 491067 D catalyzes the formation of putrescine from agmatine; agmatinase 490144..491067 Neisseria meningitidis MC58 902585 NP_273517.1 CDS NMB0470 NC_003112.2 491265 492731 D identified by similarity to EGAD:107946; match to protein family HMM PF00939; match to protein family HMM TIGR00785; C4-dicarboxylate transporter 491265..492731 Neisseria meningitidis MC58 902586 NP_273518.1 CDS NMB0471 NC_003112.2 492938 494014 R identified by similarity to EGAD:91634; match to protein family HMM PF03734; hypothetical protein complement(492938..494014) Neisseria meningitidis MC58 902587 NP_273519.1 CDS bioF NC_003112.2 494237 495379 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 494237..495379 Neisseria meningitidis MC58 902588 NP_273520.1 CDS NMB0473 NC_003112.2 495389 496036 D identified by similarity to EGAD:28546; match to protein family HMM PF04301; hypothetical protein 495389..496036 Neisseria meningitidis MC58 902589 NP_273521.1 CDS NMB0474 NC_003112.2 496024 496806 D identified by similarity to EGAD:28545; match to protein family HMM TIGR02072; biotin synthesis protein BioC 496024..496806 Neisseria meningitidis MC58 902590 NP_273522.1 CDS NMB0475 NC_003112.2 497071 498462 D hypothetical protein 497071..498462 Neisseria meningitidis MC58 902591 NP_273523.1 CDS NMB0476 NC_003112.2 498465 499562 D hypothetical protein 498465..499562 Neisseria meningitidis MC58 902592 NP_273524.1 CDS NMB0477 NC_003112.2 499574 500110 D identified by similarity to EGAD:156531; match to protein family HMM PF03029; match to protein family HMM TIGR00231; hypothetical protein 499574..500110 Neisseria meningitidis MC58 902593 NP_273525.1 CDS NMB0478 NC_003112.2 500112 500756 D hypothetical protein 500112..500756 Neisseria meningitidis MC58 902594 NP_273526.1 CDS NMB0479 NC_003112.2 500779 501138 D identified by similarity to EGAD:156541; match to protein family HMM PF03259; hypothetical protein 500779..501138 Neisseria meningitidis MC58 902595 NP_273527.1 CDS NMB0480 NC_003112.2 501806 502201 R identified by similarity to GP:3758871; TspB-like protein complement(501806..502201) Neisseria meningitidis MC58 902597 NP_273528.1 CDS NMB0481 NC_003112.2 502185 502517 R hypothetical protein complement(502185..502517) Neisseria meningitidis MC58 902598 NP_273529.1 CDS NMB0482 NC_003112.2 502630 502908 R hypothetical protein complement(502630..502908) Neisseria meningitidis MC58 902599 NP_273530.1 CDS NMB0483 NC_003112.2 502915 503199 R hypothetical protein complement(502915..503199) Neisseria meningitidis MC58 902600 NP_273531.1 CDS NMB0484 NC_003112.2 503207 503404 R hypothetical protein complement(503207..503404) Neisseria meningitidis MC58 902601 NP_273532.1 CDS NMB0485 NC_003112.2 503409 503699 R hypothetical protein complement(503409..503699) Neisseria meningitidis MC58 902602 YP_008920707.1 CDS NMB0486 NC_003112.2 503744 504778 R replication initiation factor complement(503744..504778) Neisseria meningitidis MC58 902603 NP_273534.1 CDS NMB0488 NC_003112.2 505314 505808 R hypothetical protein complement(505314..505808) Neisseria meningitidis MC58 902605 NP_273537.1 CDS NMB0491 NC_003112.2 508309 508752 R hypothetical protein complement(508309..508752) Neisseria meningitidis MC58 902608 NP_273538.1 CDS NMB0492 NC_003112.2 509068 509391 R hypothetical protein complement(509068..509391) Neisseria meningitidis MC58 902609 NP_273539.1 CDS NMB0493 NC_003112.2 509391 517502 R identified by similarity to GP:2623258; match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01731; match to protein family HMM TIGR01901; hemagglutinin/hemolysin-like protein complement(509391..517502) Neisseria meningitidis MC58 902610 NP_273540.1 CDS NMB0494 NC_003112.2 517630 518115 R identified by similarity to SP:P03005; DNA helicase, truncation complement(517630..518115) Neisseria meningitidis MC58 903201 NP_273541.1 CDS NMB0495 NC_003112.2 518212 519195 R identified by similarity to EGAD:24391; match to protein family HMM PF01051; replication protein complement(518212..519195) Neisseria meningitidis MC58 902611 NP_273542.1 CDS NMB0496 NC_003112.2 519142 520821 D identified by similarity to EGAD:10212; match to protein family HMM PF03865; hemolysin activator-like protein 519142..520821 Neisseria meningitidis MC58 902612 NP_273543.2 CDS NMB0497 NC_003112.2 520930 526866 D identified by similarity to EGAD:131268; match to protein family HMM PF04829; match to protein family HMM PF04830; match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01901; hemagglutinin/hemolysin-like protein 520930..526866 Neisseria meningitidis MC58 902613 NP_273544.1 CDS NMB0498 NC_003112.2 526873 527382 D hypothetical protein 526873..527382 Neisseria meningitidis MC58 902614 NP_273545.1 CDS NMB0499 NC_003112.2 527508 529130 D hypothetical protein 527508..529130 Neisseria meningitidis MC58 902615 NP_273546.1 CDS NMB0500 NC_003112.2 529139 529516 D hypothetical protein 529139..529516 Neisseria meningitidis MC58 902616 NP_273547.1 CDS NMB0501 NC_003112.2 529794 530168 D hypothetical protein 529794..530168 Neisseria meningitidis MC58 902617 NP_273548.1 CDS NMB0502 NC_003112.2 530203 532155 D hypothetical protein 530203..532155 Neisseria meningitidis MC58 902618 NP_273549.1 CDS NMB0503 NC_003112.2 532171 532602 D hypothetical protein 532171..532602 Neisseria meningitidis MC58 902619 NP_273552.2 CDS NMB0506 NC_003112.2 532747 535248 D hypothetical protein 532747..535248 Neisseria meningitidis MC58 902622 NP_273553.1 CDS NMB0507 NC_003112.2 535245 535733 D hypothetical protein 535245..535733 Neisseria meningitidis MC58 902623 NP_273554.1 CDS NMB0508 NC_003112.2 535920 536192 D hypothetical protein 535920..536192 Neisseria meningitidis MC58 902624 NP_273555.1 CDS NMB0509 NC_003112.2 536372 537154 D hypothetical protein 536372..537154 Neisseria meningitidis MC58 902625 NP_273556.1 CDS NMB0510 NC_003112.2 537173 537436 D hypothetical protein 537173..537436 Neisseria meningitidis MC58 902626 NP_273557.1 CDS NMB0511 NC_003112.2 537543 539465 D hypothetical protein 537543..539465 Neisseria meningitidis MC58 902627 NP_273558.1 CDS NMB0512 NC_003112.2 539474 539896 D hypothetical protein 539474..539896 Neisseria meningitidis MC58 902628 NP_273559.1 CDS NMB0513 NC_003112.2 539933 540334 D hypothetical protein 539933..540334 Neisseria meningitidis MC58 902629 NP_273562.1 CDS NMB0516 NC_003112.2 541079 542014 D hypothetical protein 541079..542014 Neisseria meningitidis MC58 902632 NP_273567.1 CDS NMB0521 NC_003112.2 543529 543987 D hypothetical protein 543529..543987 Neisseria meningitidis MC58 902637 NP_273568.1 CDS NMB0522 NC_003112.2 543995 544120 D identified by similarity to EGAD:162585; transposase, truncated 543995..544120 Neisseria meningitidis MC58 903200 NP_273569.1 CDS rbn NC_003112.2 544508 545728 R RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; this protein contains a C-terminal extension of unknown function; ribonuclease BN/unknown domain fusion protein complement(544508..545728) Neisseria meningitidis MC58 902639 NP_273570.1 CDS NMB0525 NC_003112.2 546273 546932 D identified by similarity to EGAD:28204; match to protein family HMM PF06508; match to protein family HMM TIGR00364; aluminum resistance protein 546273..546932 Neisseria meningitidis MC58 902640 NP_273571.1 CDS NMB0526 NC_003112.2 546960 547478 D hypothetical protein 546960..547478 Neisseria meningitidis MC58 902641 NP_273572.1 CDS NMB0527 NC_003112.2 547485 547907 D identified by similarity to EGAD:28193; match to protein family HMM PF01242; 6-pyruvoyl tetrahydrobiopterin synthase 547485..547907 Neisseria meningitidis MC58 902642 NP_273573.1 CDS NMB0528 NC_003112.2 548176 548547 D identified by similarity to EGAD:12599; match to protein family HMM PF06993; hypothetical protein 548176..548547 Neisseria meningitidis MC58 902643 NP_273574.1 CDS NMB0529 NC_003112.2 548544 549182 D identified by similarity to EGAD:28192; match to protein family HMM PF04055; hypothetical protein 548544..549182 Neisseria meningitidis MC58 902644 NP_273575.1 CDS NMB0530 NC_003112.2 549821 550906 R hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase complement(549821..550906) Neisseria meningitidis MC58 902646 NP_273576.1 CDS NMB0531 NC_003112.2 550963 552483 R identified by similarity to EGAD:28568; match to protein family HMM PF03553; hypothetical protein complement(550963..552483) Neisseria meningitidis MC58 902647 NP_273577.1 CDS htrA NC_003112.2 552685 554184 R identified by similarity to EGAD:16686; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; protease Do complement(552685..554184) Neisseria meningitidis MC58 903199 NP_273578.1 CDS nth NC_003112.2 554322 554951 R identified by similarity to EGAD:18451; match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III complement(554322..554951) Neisseria meningitidis MC58 902648 NP_273579.1 CDS NMB0534 NC_003112.2 554997 555410 R identified by similarity to EGAD:29125; hypothetical protein complement(554997..555410) Neisseria meningitidis MC58 902649 NP_273580.1 CDS gluP NC_003112.2 555943 557223 D identified by similarity to EGAD:41134; match to protein family HMM PF07690; match to protein family HMM TIGR01272; glucose/galactose transporter 555943..557223 Neisseria meningitidis MC58 902650 NP_273581.1 CDS NMB0536 NC_003112.2 557514 558893 D identified by similarity to EGAD:15401; match to protein family HMM PF03553; match to protein family HMM TIGR00931; Na+/H+ antiporter 557514..558893 Neisseria meningitidis MC58 902651 NP_273582.1 CDS NMB0537 NC_003112.2 559022 559846 R identified by similarity to EGAD:91441; match to protein family HMM PF00571; match to protein family HMM PF03471; hypothetical protein complement(559022..559846) Neisseria meningitidis MC58 902652 NP_273583.1 CDS NMB0538 NC_003112.2 559854 560363 R identified by similarity to EGAD:91444; match to protein family HMM PF02130; match to protein family HMM TIGR00043; hypothetical protein complement(559854..560363) Neisseria meningitidis MC58 902653 NP_273584.1 CDS hemC NC_003112.2 560482 561417 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 560482..561417 Neisseria meningitidis MC58 902654 NP_273585.1 CDS aspC NC_003112.2 561821 563014 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(561821..563014) Neisseria meningitidis MC58 902655 NP_273586.1 CDS NMB0541 NC_003112.2 563096 563593 R hypothetical protein complement(563096..563593) Neisseria meningitidis MC58 902656 NP_273587.1 CDS NMB0542 NC_003112.2 563709 563912 D hypothetical protein 563709..563912 Neisseria meningitidis MC58 902657 NP_273588.1 CDS NMB0543 NC_003112.2 564081 565667 R identified by similarity to EGAD:28220; match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease complement(564081..565667) Neisseria meningitidis MC58 902658 NP_273589.1 CDS NMB0544 NC_003112.2 565936 566658 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(565936..566658) Neisseria meningitidis MC58 902659 NP_273590.1 CDS NMB0545 NC_003112.2 566907 570392 D identified by similarity to EGAD:37839; match to protein family HMM PF02463; match to protein family HMM PF02483; match to protein family HMM TIGR02168; hypothetical protein 566907..570392 Neisseria meningitidis MC58 902660 NP_273591.2 CDS adhP NC_003112.2 570557 571597 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(570557..571597) Neisseria meningitidis MC58 902661 NP_273592.1 CDS NMB0547 NC_003112.2 571886 572275 R identified by similarity to EGAD:20241; match to protein family HMM PF07963; match to protein family HMM TIGR02532; type IV pilin protein complement(571886..572275) Neisseria meningitidis MC58 902662 NP_273593.1 CDS NMB0548 NC_003112.2 572501 573679 D identified by similarity to EGAD:91761; match to protein family HMM PF00529; match to protein family HMM TIGR01730; AcrA/AcrE family protein 572501..573679 Neisseria meningitidis MC58 902663 NP_273594.1 CDS ybjZ NC_003112.2 573745 575679 D identified by similarity to EGAD:91762; match to protein family HMM PF00005; match to protein family HMM PF02687; ABC transporter ATP-binding protein 573745..575679 Neisseria meningitidis MC58 902664 NP_273595.1 CDS dsbC NC_003112.2 576092 576874 R identified by similarity to GP:3135321; thiol:disulfide interchange protein DsbC complement(576092..576874) Neisseria meningitidis MC58 902665 NP_273596.1 CDS priA NC_003112.2 577012 579201 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 577012..579201 Neisseria meningitidis MC58 902666 NP_273597.1 CDS NMB0552 NC_003112.2 579248 580321 R hypothetical protein complement(579248..580321) Neisseria meningitidis MC58 902667 NP_273598.1 CDS dnaK NC_003112.2 582560 584488 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(582560..584488) Neisseria meningitidis MC58 902669 NP_273599.1 CDS NMB0555 NC_003112.2 584696 584968 R hypothetical protein complement(584696..584968) Neisseria meningitidis MC58 902670 NP_273600.1 CDS NMB0556 NC_003112.2 585156 585842 D identified by similarity to EGAD:140303; match to protein family HMM PF00717; repressor protein 585156..585842 Neisseria meningitidis MC58 902671 NP_273601.1 CDS NMB0557 NC_003112.2 585974 586312 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 585974..586312 Neisseria meningitidis MC58 902672 NP_273602.1 CDS NMB0558 NC_003112.2 586472 586936 D hypothetical protein 586472..586936 Neisseria meningitidis MC58 902673 NP_273603.1 CDS ubiB NC_003112.2 586971 588482 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 586971..588482 Neisseria meningitidis MC58 902674 NP_273604.1 CDS cysE NC_003112.2 588839 589657 R identified by similarity to EGAD:29240; match to protein family HMM PF00132; match to protein family HMM PF06426; match to protein family HMM TIGR01172; serine acetyltransferase complement(588839..589657) Neisseria meningitidis MC58 902675 NP_273605.1 CDS grpE NC_003112.2 589841 590419 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 589841..590419 Neisseria meningitidis MC58 902676 NP_273606.1 CDS NMB0562 NC_003112.2 590696 590911 R identified by similarity to EGAD:28820; match to protein family HMM PF04400; hypothetical protein complement(590696..590911) Neisseria meningitidis MC58 902677 NP_273607.1 CDS apbE NC_003112.2 590937 591992 R identified by similarity to EGAD:28819; match to protein family HMM PF02424; thiamine biosynthesis lipoprotein ApbE complement(590937..591992) Neisseria meningitidis MC58 902678 NP_273608.1 CDS nqrF NC_003112.2 592145 593362 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F complement(592145..593362) Neisseria meningitidis MC58 902679 NP_273609.1 CDS nqrE NC_003112.2 593376 593969 R Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E complement(593376..593969) Neisseria meningitidis MC58 902680 NP_273610.1 CDS nqrD NC_003112.2 593973 594599 R Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D complement(593973..594599) Neisseria meningitidis MC58 902681 NP_273611.1 CDS nqrC NC_003112.2 594599 595375 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C complement(594599..595375) Neisseria meningitidis MC58 902682 NP_273612.1 CDS nqrB NC_003112.2 595368 596600 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B complement(595368..596600) Neisseria meningitidis MC58 902683 NP_273613.1 CDS nqrA NC_003112.2 596603 597946 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A complement(596603..597946) Neisseria meningitidis MC58 902684 NP_273614.1 CDS NMB0570 NC_003112.2 598296 599717 R hypothetical protein complement(598296..599717) Neisseria meningitidis MC58 902685 NP_273615.1 CDS NMB0571 NC_003112.2 600078 600437 R identified by similarity to EGAD:29947; match to protein family HMM PF04304; hypothetical protein complement(600078..600437) Neisseria meningitidis MC58 902686 NP_273616.1 CDS NMB0572 NC_003112.2 600434 601039 R hypothetical protein complement(600434..601039) Neisseria meningitidis MC58 902687 NP_273617.1 CDS NMB0573 NC_003112.2 601086 601649 R identified by similarity to GP:1272513; match to protein family HMM PF01037; AsnC family transcriptional regulator complement(601086..601649) Neisseria meningitidis MC58 902688 NP_273618.1 CDS gcvT NC_003112.2 602079 603179 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 602079..603179 Neisseria meningitidis MC58 902689 NP_273619.1 CDS gcvH NC_003112.2 603341 603727 D part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 603341..603727 Neisseria meningitidis MC58 902690 NP_273620.1 CDS hemA NC_003112.2 603879 605126 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 603879..605126 Neisseria meningitidis MC58 902691 NP_273621.1 CDS NMB0577 NC_003112.2 605402 605974 D identified by similarity to GP:2935358; NosR-like protein 605402..605974 Neisseria meningitidis MC58 902692 NP_273622.1 CDS nosD NC_003112.2 606028 607062 D identified by similarity to EGAD:35473; match to protein family HMM PF05048; copper ABC transporter substrate-binding protein 606028..607062 Neisseria meningitidis MC58 902693 NP_273623.1 CDS nosF NC_003112.2 607120 607740 D identified by similarity to EGAD:35474; match to protein family HMM PF00005; copper ABC transporter ATP-binding protein 607120..607740 Neisseria meningitidis MC58 902694 NP_273624.1 CDS NMB0580 NC_003112.2 607879 608373 D identified by similarity to GP:2177177; match to protein family HMM PF05573; protein disulfide isomerase NosL 607879..608373 Neisseria meningitidis MC58 902695 NP_273625.1 CDS NMB0581 NC_003112.2 608461 610122 R identified by similarity to EGAD:128939; match to protein family HMM PF05187; electron transfer flavoprotein-ubiquinone oxidoreductase complement(608461..610122) Neisseria meningitidis MC58 902696 NP_273626.1 CDS NMB0582 NC_003112.2 610252 610794 R identified by similarity to GP:2909665; match to protein family HMM PF03412; bacteriocin resistance protein complement(610252..610794) Neisseria meningitidis MC58 902697 NP_273627.1 CDS NMB0583 NC_003112.2 612020 612688 R identified by similarity to GP:4102010; IS1016C2 transposase complement(612020..612688) Neisseria meningitidis MC58 902698 NP_273628.1 CDS NMB0584 NC_003112.2 613279 614094 D identified by similarity to EGAD:20116; match to protein family HMM PF06901; FrpC operon protein 613279..614094 Neisseria meningitidis MC58 902699 NP_273629.1 CDS NMB0585 NC_003112.2 614111 618019 D identified by similarity to EGAD:18289; match to protein family HMM PF00353; iron-regulated protein FrpA 614111..618019 Neisseria meningitidis MC58 902700 NP_273630.1 CDS NMB0586 NC_003112.2 618299 619213 R identified by similarity to EGAD:16475; match to protein family HMM PF01297; adhesin complement(618299..619213) Neisseria meningitidis MC58 902701 NP_273631.1 CDS NMB0587 NC_003112.2 619290 620165 R identified by similarity to EGAD:15708; match to protein family HMM PF00950; membrane protein complement(619290..620165) Neisseria meningitidis MC58 902702 NP_273632.1 CDS NMB0588 NC_003112.2 620189 620944 R identified by similarity to EGAD:153448; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(620189..620944) Neisseria meningitidis MC58 902703 NP_273633.1 CDS rplS NC_003112.2 621235 621600 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(621235..621600) Neisseria meningitidis MC58 902704 NP_273634.1 CDS trmD NC_003112.2 621616 622365 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(621616..622365) Neisseria meningitidis MC58 902705 NP_273635.1 CDS rimM NC_003112.2 622365 622874 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(622365..622874) Neisseria meningitidis MC58 902706 NP_273636.1 CDS rpsP NC_003112.2 622890 623135 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(622890..623135) Neisseria meningitidis MC58 902707 NP_273637.1 CDS NMB0593 NC_003112.2 623180 625606 R identified by similarity to EGAD:37591; match to protein family HMM PF00583; match to protein family HMM PF02629; hypothetical protein complement(623180..625606) Neisseria meningitidis MC58 902708 NP_273638.1 CDS NMB0594 NC_003112.2 625724 627130 R identified by similarity to GP:208252; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase complement(625724..627130) Neisseria meningitidis MC58 902709 NP_273639.1 CDS NMB0595 NC_003112.2 627144 627821 R identified by similarity to EGAD:40657; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator complement(627144..627821) Neisseria meningitidis MC58 902710 NP_273640.1 CDS NMB0596 NC_003112.2 628011 629825 R hypothetical protein complement(628011..629825) Neisseria meningitidis MC58 902711 NP_273641.1 CDS NMB0597 NC_003112.2 629815 630168 R hypothetical protein complement(629815..630168) Neisseria meningitidis MC58 902712 NP_273642.1 CDS NMB0598 NC_003112.2 630177 630785 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(630177..630785) Neisseria meningitidis MC58 902713 NP_273643.1 CDS NMB0599 NC_003112.2 630838 631608 R identified by similarity to EGAD:35952; match to protein family HMM PF00902; match to protein family HMM TIGR00945; hypothetical protein complement(630838..631608) Neisseria meningitidis MC58 902714 NP_273644.1 CDS NMB0600 NC_003112.2 631622 632308 R hypothetical protein complement(631622..632308) Neisseria meningitidis MC58 902715 NP_273645.1 CDS tatA NC_003112.2 632312 632515 R TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A complement(632312..632515) Neisseria meningitidis MC58 903198 NP_273646.1 CDS hitA NC_003112.2 632562 632885 R identified by similarity to EGAD:149280; match to protein family HMM PF01230; HitA protein complement(632562..632885) Neisseria meningitidis MC58 902716 NP_273647.1 CDS hisE NC_003112.2 632957 633280 R catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase complement(632957..633280) Neisseria meningitidis MC58 902717 NP_273648.1 CDS NMB0604 NC_003112.2 633421 634485 R identified by similarity to EGAD:107561; match to protein family HMM PF00107; alcohol dehydrogenase complement(633421..634485) Neisseria meningitidis MC58 902718 NP_273649.1 CDS NMB0605 NC_003112.2 635034 636143 R identified by similarity to EGAD:48895; match to protein family HMM PF00850; histone deacetylase complement(635034..636143) Neisseria meningitidis MC58 902719 NP_273650.1 CDS NMB0606 NC_003112.2 636271 636537 D identified by similarity to EGAD:166065; match to protein family HMM PF02699; match to protein family HMM TIGR00739; hypothetical protein 636271..636537 Neisseria meningitidis MC58 902720 NP_273651.1 CDS secD NC_003112.2 636746 638602 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 636746..638602 Neisseria meningitidis MC58 902721 NP_273652.1 CDS secF NC_003112.2 638606 639541 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 638606..639541 Neisseria meningitidis MC58 902722 NP_273653.1 CDS rpsO NC_003112.2 639764 640033 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 639764..640033 Neisseria meningitidis MC58 902723 NP_273654.1 CDS potA-1 NC_003112.2 640279 641538 D identified by similarity to EGAD:19034; match to protein family HMM PF00005; match to protein family HMM TIGR01187; spermidine/putrescine ABC transporter ATP-binding protein 640279..641538 Neisseria meningitidis MC58 902724 NP_273655.1 CDS potB NC_003112.2 641554 642519 D identified by similarity to EGAD:21628; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 641554..642519 Neisseria meningitidis MC58 902725 NP_273656.1 CDS potC NC_003112.2 642519 643406 D identified by similarity to EGAD:18692; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 642519..643406 Neisseria meningitidis MC58 902726 NP_273657.1 CDS NMB0613 NC_003112.2 643428 643535 D hypothetical protein 643428..643535 Neisseria meningitidis MC58 902727 NP_273658.1 CDS NMB0614 NC_003112.2 643532 644827 D identified by similarity to EGAD:29135; oxidoreductase 643532..644827 Neisseria meningitidis MC58 902728 NP_273659.1 CDS NMB0615 NC_003112.2 645072 646376 R identified by similarity to GP:3136068; match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter AmtB complement(645072..646376) Neisseria meningitidis MC58 902729 NP_273661.1 CDS rho NC_003112.2 647614 648873 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(647614..648873) Neisseria meningitidis MC58 902730 NP_273662.1 CDS ppsA NC_003112.2 649093 651477 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(649093..651477) Neisseria meningitidis MC58 902731 NP_273663.1 CDS NMB0619 NC_003112.2 651889 652710 D identified by similarity to EGAD:7555; match to protein family HMM PF03618; hypothetical protein 651889..652710 Neisseria meningitidis MC58 902732 NP_273664.1 CDS pgp NC_003112.2 652949 653611 R identified by similarity to EGAD:155362; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; phosphoglycolate phosphatase complement(652949..653611) Neisseria meningitidis MC58 902733 NP_273665.1 CDS NMB0621 NC_003112.2 653649 654476 R identified by similarity to EGAD:28731; match to protein family HMM PF04305; hypothetical protein complement(653649..654476) Neisseria meningitidis MC58 902734 NP_273666.1 CDS lolA NC_003112.2 654903 655526 D identified by similarity to GP:4063381; match to protein family HMM PF03548; match to protein family HMM TIGR00547; outer membrane lipoprotein carrier protein 654903..655526 Neisseria meningitidis MC58 902735 NP_273667.1 CDS potD-2 NC_003112.2 655799 656938 D identified by similarity to EGAD:21832; match to protein family HMM PF01547; spermidine/putrescine ABC transporter substrate-binding protein 655799..656938 Neisseria meningitidis MC58 902736 NP_273668.1 CDS NMB0625 NC_003112.2 658333 658863 D identified by similarity to EGAD:29917; match to protein family HMM PF00132; hypothetical protein 658333..658863 Neisseria meningitidis MC58 902738 NP_273669.1 CDS prfC NC_003112.2 659238 660833 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(659238..660833) Neisseria meningitidis MC58 902739 NP_273670.1 CDS hisI NC_003112.2 660940 661335 R PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase complement(660940..661335) Neisseria meningitidis MC58 902740 NP_273671.1 CDS hisF NC_003112.2 661366 662133 R catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF complement(661366..662133) Neisseria meningitidis MC58 902741 NP_273672.1 CDS hisA NC_003112.2 662146 662883 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase complement(662146..662883) Neisseria meningitidis MC58 902742 NP_273673.1 CDS hisH NC_003112.2 662916 663554 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(662916..663554) Neisseria meningitidis MC58 902743 NP_273674.1 CDS NMB0631 NC_003112.2 663685 665187 R identified by similarity to EGAD:28215; match to protein family HMM PF01515; match to protein family HMM TIGR00651; phosphate acetyltransferase complement(663685..665187) Neisseria meningitidis MC58 902744 NP_273675.1 CDS fbpC NC_003112.2 665372 666430 R identified by similarity to EGAD:40676; match to protein family HMM PF00005; iron(III) ABC transporter ATP-binding protein complement(665372..666430) Neisseria meningitidis MC58 903196 NP_273676.1 CDS fbpB NC_003112.2 666451 667968 R identified by similarity to EGAD:40675; match to protein family HMM PF00528; iron(III) ABC transporter permease complement(666451..667968) Neisseria meningitidis MC58 903195 NP_273677.1 CDS fbpA NC_003112.2 668036 669031 R identified by similarity to EGAD:7909; match to protein family HMM PF01547; iron ABC transporter substrate-binding protein complement(668036..669031) Neisseria meningitidis MC58 902745 NP_273678.1 CDS NMB0635 NC_003112.2 669318 670283 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; transposase IS30 complement(669318..670283) Neisseria meningitidis MC58 902746 NP_273680.1 CDS argH NC_003112.2 670888 672264 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(670888..672264) Neisseria meningitidis MC58 902748 NP_273681.1 CDS galU NC_003112.2 672283 673152 R identified by similarity to EGAD:153516; match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase complement(672283..673152) Neisseria meningitidis MC58 902749 NP_273682.1 CDS NMB0639 NC_003112.2 673180 673779 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase complement(673180..673779) Neisseria meningitidis MC58 902750 NP_273683.1 CDS NMB0640 NC_003112.2 673772 674005 R hypothetical protein complement(673772..674005) Neisseria meningitidis MC58 902751 NP_273684.1 CDS ppa NC_003112.2 674113 674646 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(674113..674646) Neisseria meningitidis MC58 902752 NP_273685.1 CDS ntpA NC_003112.2 674747 675205 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(674747..675205) Neisseria meningitidis MC58 902753 NP_273686.1 CDS NMB0643 NC_003112.2 675650 677476 D identified by similarity to GP:4838555; match to protein family HMM PF06255; MafB-like protein 675650..677476 Neisseria meningitidis MC58 902755 NP_273687.1 CDS NMB0644 NC_003112.2 677479 677943 D hypothetical protein 677479..677943 Neisseria meningitidis MC58 902756 NP_273688.1 CDS NMB0646 NC_003112.2 678326 678613 D identified by similarity to EGAD:16283; match to protein family HMM PF01337; ribonuclease inhibitor barstar 678326..678613 Neisseria meningitidis MC58 902758 NP_273690.1 CDS NMB0648 NC_003112.2 680393 680815 D hypothetical protein 680393..680815 Neisseria meningitidis MC58 902760 NP_273691.1 CDS NMB0649 NC_003112.2 681006 681230 D hypothetical protein 681006..681230 Neisseria meningitidis MC58 902761 NP_273692.1 CDS NMB0650 NC_003112.2 681203 681622 D hypothetical protein 681203..681622 Neisseria meningitidis MC58 902762 NP_273693.1 CDS NMB0651 NC_003112.2 681723 682112 D hypothetical protein 681723..682112 Neisseria meningitidis MC58 902763 NP_273694.1 CDS mafA-2 NC_003112.2 682235 683176 D identified by similarity to GP:4838554; mafA protein 682235..683176 Neisseria meningitidis MC58 902764 NP_273695.1 CDS NMB0653 NC_003112.2 683180 684448 D identified by similarity to GP:4838555; match to protein family HMM PF06255; MafB-like protein 683180..684448 Neisseria meningitidis MC58 902765 NP_273696.1 CDS NMB0654 NC_003112.2 684451 684768 D hypothetical protein 684451..684768 Neisseria meningitidis MC58 902766 NP_273697.1 CDS NMB0655 NC_003112.2 684903 685610 D hypothetical protein 684903..685610 Neisseria meningitidis MC58 902767 NP_273698.1 CDS NMB0656 NC_003112.2 685636 685965 D hypothetical protein 685636..685965 Neisseria meningitidis MC58 902768 NP_273701.1 CDS NMB0659 NC_003112.2 686382 686783 D hypothetical protein 686382..686783 Neisseria meningitidis MC58 902771 NP_273702.1 CDS NMB0660 NC_003112.2 686965 687354 D hypothetical protein 686965..687354 Neisseria meningitidis MC58 902772 NP_273703.2 CDS NMB0661 NC_003112.2 687395 688852 R identified by similarity to EGAD:13777; match to protein family HMM TIGR00668; bis(5'-nucleosyl)-tetraphosphatase complement(687395..688852) Neisseria meningitidis MC58 903194 NP_273704.1 CDS NMB0662 NC_003112.2 689773 690162 R identified by similarity to EGAD:30582; match to protein family HMM PF01042; match to protein family HMM TIGR00004; ribonuclease complement(689773..690162) Neisseria meningitidis MC58 902773 NP_273705.1 CDS nspA NC_003112.2 690298 690822 R identified by similarity to EGAD:137514; match to protein family HMM PF02462; outer membrane protein complement(690298..690822) Neisseria meningitidis MC58 902774 NP_273707.1 CDS NMB0665 NC_003112.2 691407 692582 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(691407..692582) Neisseria meningitidis MC58 902776 NP_273708.1 CDS ligA-1 NC_003112.2 692639 695164 R identified by similarity to EGAD:14652; match to protein family HMM PF00533; match to protein family HMM PF01653; match to protein family HMM PF03119; match to protein family HMM PF03120; match to protein family HMM TIGR00575; DNA ligase complement(692639..695164) Neisseria meningitidis MC58 902777 NP_273709.1 CDS NMB0667 NC_003112.2 695312 696598 R hypothetical protein complement(695312..696598) Neisseria meningitidis MC58 902778 NP_273710.1 CDS ampD NC_003112.2 696816 697388 R identified by similarity to EGAD:17713; match to protein family HMM PF01510; N-acetyl-anhydromuranmyl-L-alanine amidase complement(696816..697388) Neisseria meningitidis MC58 902779 NP_273711.1 CDS NMB0669 NC_003112.2 697472 698467 D identified by similarity to EGAD:46980; match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 697472..698467 Neisseria meningitidis MC58 902780 NP_273712.1 CDS tmk NC_003112.2 698527 699147 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 698527..699147 Neisseria meningitidis MC58 902781 NP_273713.1 CDS sfcA NC_003112.2 699369 700649 D identified by similarity to GP:1799887; match to protein family HMM PF00390; match to protein family HMM PF03949; malate oxidoreductase (NAD) 699369..700649 Neisseria meningitidis MC58 902782 NP_273714.1 CDS lpxK NC_003112.2 701196 702230 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 701196..702230 Neisseria meningitidis MC58 902783 NP_273715.1 CDS NMB0673 NC_003112.2 702430 703017 D hypothetical protein 702430..703017 Neisseria meningitidis MC58 902784 NP_273716.1 CDS NMB0674 NC_003112.2 703086 703268 D identified by similarity to EGAD:90683; match to protein family HMM PF03966; hypothetical protein 703086..703268 Neisseria meningitidis MC58 902785 NP_273717.1 CDS kdsB NC_003112.2 703265 704026 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 703265..704026 Neisseria meningitidis MC58 902786 NP_273718.1 CDS NMB0676 NC_003112.2 704049 704450 D hypothetical protein 704049..704450 Neisseria meningitidis MC58 902787 NP_273720.1 CDS trpA NC_003112.2 705342 706127 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 705342..706127 Neisseria meningitidis MC58 902790 NP_273721.1 CDS accD NC_003112.2 706165 707037 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 706165..707037 Neisseria meningitidis MC58 902791 NP_273722.1 CDS cnp1 NC_003112.2 707097 707708 R identified by similarity to EGAD:20133; hypothetical protein complement(707097..707708) Neisseria meningitidis MC58 902792 NP_273723.1 CDS NMB0681 NC_003112.2 707817 708041 D identified by similarity to EGAD:45778; match to protein family HMM PF01206; hypothetical protein 707817..708041 Neisseria meningitidis MC58 902793 NP_273724.1 CDS pyrC NC_003112.2 708404 709438 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 708404..709438 Neisseria meningitidis MC58 902794 NP_273725.1 CDS nusB NC_003112.2 709806 710231 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(709806..710231) Neisseria meningitidis MC58 902795 NP_273726.1 CDS ribH NC_003112.2 710309 710785 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(710309..710785) Neisseria meningitidis MC58 902796 NP_273727.1 CDS NMB0685 NC_003112.2 710833 711156 R hypothetical protein complement(710833..711156) Neisseria meningitidis MC58 902797 NP_273728.1 CDS rnc NC_003112.2 711323 712042 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 711323..712042 Neisseria meningitidis MC58 902798 NP_273729.1 CDS era NC_003112.2 712039 713013 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 712039..713013 Neisseria meningitidis MC58 902799 NP_273730.1 CDS trpF NC_003112.2 714856 715482 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(714856..715482) Neisseria meningitidis MC58 902800 NP_273731.1 CDS greB NC_003112.2 715541 716032 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB complement(715541..716032) Neisseria meningitidis MC58 902801 NP_273732.1 CDS purF NC_003112.2 716132 717676 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(716132..717676) Neisseria meningitidis MC58 902802 NP_273733.1 CDS NMB0691 NC_003112.2 717989 718486 R identified by similarity to EGAD:28218; match to protein family HMM PF02674; colicin V production protein complement(717989..718486) Neisseria meningitidis MC58 902803 NP_273734.1 CDS tpc NC_003112.2 718479 719477 R identified by similarity to EGAD:40704; match to protein family HMM PF05036; match to protein family HMM TIGR02223; tpc protein complement(718479..719477) Neisseria meningitidis MC58 902804 NP_273735.1 CDS folC NC_003112.2 719490 720764 R identified by similarity to EGAD:40703; match to protein family HMM TIGR01499; bifunctional folylpolyglutamate synthase/dihydrofolate synthase complement(719490..720764) Neisseria meningitidis MC58 902805 NP_273736.1 CDS folI NC_003112.2 720795 721241 R identified by similarity to EGAD:40702; folI protein complement(720795..721241) Neisseria meningitidis MC58 902806 NP_273737.1 CDS NMB0695 NC_003112.2 721246 721605 R hypothetical protein complement(721246..721605) Neisseria meningitidis MC58 902807 NP_273738.1 CDS NMB0696 NC_003112.2 721678 722406 R identified by similarity to EGAD:12339; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein complement(721678..722406) Neisseria meningitidis MC58 902808 NP_273739.1 CDS ksgA NC_003112.2 722579 723358 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(722579..723358) Neisseria meningitidis MC58 902809 NP_273740.1 CDS NMB0698 NC_003112.2 723555 724244 D hypothetical protein 723555..724244 Neisseria meningitidis MC58 902810 NP_273741.1 CDS trpB NC_003112.2 724327 725529 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 724327..725529 Neisseria meningitidis MC58 902811 NP_273742.1 CDS iga NC_003112.2 725708 731155 R identified by similarity to GP:732874; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; IgA-specific serine endopeptidase complement(725708..731155) Neisseria meningitidis MC58 902812 NP_273744.1 CDS comA NC_003112.2 732566 734641 D identified by similarity to EGAD:32733; match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; competence protein 732566..734641 Neisseria meningitidis MC58 902814 NP_273745.1 CDS comL NC_003112.2 734869 735672 R identified by similarity to EGAD:40678; match to protein family HMM PF03696; competence lipoprotein complement(734869..735672) Neisseria meningitidis MC58 902815 NP_273746.1 CDS rluD NC_003112.2 735671 736795 D identified by similarity to EGAD:5430; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D 735671..736795 Neisseria meningitidis MC58 902816 NP_273747.1 CDS NMB0705 NC_003112.2 736948 737895 R identified by similarity to EGAD:109243; match to protein family HMM PF01758; transporter complement(736948..737895) Neisseria meningitidis MC58 902817 NP_273748.1 CDS NMB0706 NC_003112.2 738455 739234 D identified by similarity to EGAD:9801; match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 738455..739234 Neisseria meningitidis MC58 902818 NP_273749.1 CDS NMB0707 NC_003112.2 739286 739765 D identified by similarity to EGAD:24661; match to protein family HMM PF04390; rare lipoprotein B 739286..739765 Neisseria meningitidis MC58 902819 NP_273750.1 CDS holA NC_003112.2 739767 740765 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 739767..740765 Neisseria meningitidis MC58 902820 NP_273751.1 CDS NMB0709 NC_003112.2 740886 741305 D hypothetical protein 740886..741305 Neisseria meningitidis MC58 902821 NP_273752.1 CDS NMB0710 NC_003112.2 741330 741896 D hypothetical protein 741330..741896 Neisseria meningitidis MC58 902822 NP_273753.1 CDS NMB0711 NC_003112.2 741980 742864 R identified by similarity to EGAD:15764; match to protein family HMM PF03755; match to protein family HMM TIGR00255; hypothetical protein complement(741980..742864) Neisseria meningitidis MC58 902823 NP_273754.1 CDS rpoH NC_003112.2 743348 744220 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(743348..744220) Neisseria meningitidis MC58 902824 NP_273755.1 CDS lnt NC_003112.2 744476 746050 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(744476..746050) Neisseria meningitidis MC58 902825 NP_273757.1 CDS NMB0715 NC_003112.2 747005 747325 D hypothetical protein 747005..747325 Neisseria meningitidis MC58 902827 NP_273758.1 CDS NMB0716 NC_003112.2 747478 747768 D hypothetical protein 747478..747768 Neisseria meningitidis MC58 902828 NP_273759.1 CDS NMB0717 NC_003112.2 747831 748247 R identified by similarity to EGAD:40915; match to protein family HMM PF00034; cytochrome complement(747831..748247) Neisseria meningitidis MC58 902829 NP_273760.1 CDS hemH NC_003112.2 748528 749610 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(748528..749610) Neisseria meningitidis MC58 902830 NP_273761.1 CDS tgt NC_003112.2 749620 750735 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(749620..750735) Neisseria meningitidis MC58 902831 NP_273762.1 CDS thrS NC_003112.2 751043 752956 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 751043..752956 Neisseria meningitidis MC58 902833 NP_273763.1 CDS infC NC_003112.2 753028 753495 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 753028..753495 Neisseria meningitidis MC58 902834 NP_273764.1 CDS rpmI NC_003112.2 753642 753839 D identified by similarity to GP:3095163; match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 753642..753839 Neisseria meningitidis MC58 902835 NP_273765.1 CDS rplT NC_003112.2 753852 754211 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 753852..754211 Neisseria meningitidis MC58 902836 NP_273766.1 CDS pheS NC_003112.2 754557 755549 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 754557..755549 Neisseria meningitidis MC58 902837 NP_273767.1 CDS NMB0725 NC_003112.2 755732 756790 D identified by similarity to EGAD:15667; match to protein family HMM PF00145; match to protein family HMM TIGR00675; modification methylase HgaI-1 755732..756790 Neisseria meningitidis MC58 902838 NP_273768.1 CDS NMB0726 NC_003112.2 756793 758262 D identified by similarity to EGAD:14414; type II restriction enzyme HgaI 756793..758262 Neisseria meningitidis MC58 902839 NP_273769.1 CDS NMB0727 NC_003112.2 758259 758909 D identified by similarity to EGAD:89170; match to protein family HMM PF01555; N-6 adenine-specific DNA methylase 758259..758909 Neisseria meningitidis MC58 902840 NP_273770.1 CDS pheT NC_003112.2 758934 761297 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 758934..761297 Neisseria meningitidis MC58 902841 NP_273771.1 CDS ihfA NC_003112.2 761371 761673 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 761371..761673 Neisseria meningitidis MC58 902842 NP_273772.1 CDS fxsA NC_003112.2 762295 762780 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 762295..762780 Neisseria meningitidis MC58 902843 NP_273773.1 CDS NMB0731 NC_003112.2 763040 763267 D hypothetical protein 763040..763267 Neisseria meningitidis MC58 902844 NP_273774.1 CDS bioA NC_003112.2 763597 764898 D identified by similarity to EGAD:28548; match to protein family HMM PF00202; match to protein family HMM TIGR00508; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 763597..764898 Neisseria meningitidis MC58 902845 NP_273775.1 CDS bioD NC_003112.2 764895 765542 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 764895..765542 Neisseria meningitidis MC58 902846 NP_273776.1 CDS NMB0734 NC_003112.2 765557 766033 D hypothetical protein 765557..766033 Neisseria meningitidis MC58 902847 NP_273777.1 CDS ubiA NC_003112.2 766063 766953 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 766063..766953 Neisseria meningitidis MC58 902848 NP_273778.1 CDS ptsN NC_003112.2 767138 767587 D identified by similarity to EGAD:15747; match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system, nitrogen regulatory IIA protein 767138..767587 Neisseria meningitidis MC58 902849 NP_273779.1 CDS NMB0737 NC_003112.2 767589 768551 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 767589..768551 Neisseria meningitidis MC58 902850 NP_273780.1 CDS NMB0738 NC_003112.2 768532 769386 D identified by similarity to EGAD:28161; match to protein family HMM PF03668; hypothetical protein 768532..769386 Neisseria meningitidis MC58 902851 NP_273781.1 CDS NMB0739 NC_003112.2 769467 770984 D identified by similarity to EGAD:108433; match to protein family HMM PF01926; match to protein family HMM PF04079; match to protein family HMM TIGR00650; hypothetical protein 769467..770984 Neisseria meningitidis MC58 902852 NP_273782.1 CDS recN NC_003112.2 771293 772966 D identified by similarity to GP:1788969; match to protein family HMM TIGR00634; DNA repair protein RecN 771293..772966 Neisseria meningitidis MC58 902853 NP_273783.1 CDS NMB0741 NC_003112.2 773983 775422 R identified by similarity to EGAD:90903; hypothetical protein complement(773983..775422) Neisseria meningitidis MC58 902856 NP_273784.1 CDS NMB0742 NC_003112.2 775722 776081 D identified by similarity to EGAD:19920; match to protein family HMM PF06155; hypothetical protein 775722..776081 Neisseria meningitidis MC58 902857 NP_273785.1 CDS ubiE NC_003112.2 776135 776872 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 776135..776872 Neisseria meningitidis MC58 902858 NP_273786.1 CDS NMB0744 NC_003112.2 777092 777571 D hypothetical protein 777092..777571 Neisseria meningitidis MC58 902859 NP_273787.1 CDS folK NC_003112.2 777697 778191 R identified by similarity to EGAD:27899; match to protein family HMM PF01288; match to protein family HMM TIGR01498; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(777697..778191) Neisseria meningitidis MC58 902860 NP_273788.1 CDS NMB0746 NC_003112.2 778201 778575 R identified by similarity to EGAD:36863; match to protein family HMM PF04247; hypothetical protein complement(778201..778575) Neisseria meningitidis MC58 902861 NP_273789.1 CDS NMB0747 NC_003112.2 778629 779195 R identified by similarity to EGAD:108409; match to protein family HMM PF06962; hypothetical protein complement(778629..779195) Neisseria meningitidis MC58 902862 NP_273790.1 CDS hfq NC_003112.2 779280 779573 R identified by similarity to GP:146861; match to protein family HMM PF01423; match to protein family HMM TIGR02383; host factor-I complement(779280..779573) Neisseria meningitidis MC58 902863 NP_273791.1 CDS NMB0749 NC_003112.2 779702 780640 R identified by similarity to EGAD:8088; match to protein family HMM PF00768; penicillin-binding protein 4 complement(779702..780640) Neisseria meningitidis MC58 902864 NP_273792.1 CDS bcp NC_003112.2 780961 781401 D identified by similarity to EGAD:48892; match to protein family HMM PF00578; bacterioferritin comigratory protein 780961..781401 Neisseria meningitidis MC58 902865 NP_273793.1 CDS xerD NC_003112.2 781453 782328 D identified by similarity to EGAD:24225; match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02225; integrase/recombinase XerD 781453..782328 Neisseria meningitidis MC58 902866 NP_273794.1 CDS NMB0752 NC_003112.2 782500 782700 D identified by similarity to GP:4378826; match to protein family HMM PF04324; bacterioferritin-associated ferredoxin 782500..782700 Neisseria meningitidis MC58 902867 NP_273795.1 CDS NMB0753 NC_003112.2 782866 783099 D identified by similarity to EGAD:46419; hypothetical protein 782866..783099 Neisseria meningitidis MC58 902868 NP_273796.1 CDS NMB0754 NC_003112.2 783104 783214 D hypothetical protein 783104..783214 Neisseria meningitidis MC58 902869 NP_273797.1 CDS NMB0755 NC_003112.2 783232 783375 D hypothetical protein 783232..783375 Neisseria meningitidis MC58 902870 NP_273798.1 CDS NMB0756 NC_003112.2 783516 784436 R identified by similarity to GP:2662408; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214; dTDP-L-rhamnose synthase complement(783516..784436) Neisseria meningitidis MC58 902871 NP_273799.1 CDS hemH NC_003112.2 784636 785499 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 784636..785499 Neisseria meningitidis MC58 902872 NP_273800.1 CDS pnp NC_003112.2 785733 787856 D identified by similarity to EGAD:12417; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase 785733..787856 Neisseria meningitidis MC58 902873 NP_273801.1 CDS NMB0759 NC_003112.2 787929 788657 R identified by similarity to EGAD:89407; hypothetical protein complement(787929..788657) Neisseria meningitidis MC58 902874 NP_273802.1 CDS dapF NC_003112.2 789044 789895 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 789044..789895 Neisseria meningitidis MC58 902875 NP_273803.1 CDS NMB0761 NC_003112.2 789978 790205 D hypothetical protein 789978..790205 Neisseria meningitidis MC58 902876 NP_273805.1 CDS cysK NC_003112.2 790691 791623 D identified by similarity to EGAD:160962; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase 790691..791623 Neisseria meningitidis MC58 902878 NP_273806.1 CDS NMB0764 NC_003112.2 792086 792991 D identified by similarity to GP:3413203; match to protein family HMM PF00892; hypothetical protein 792086..792991 Neisseria meningitidis MC58 902879 NP_273807.1 CDS lepB NC_003112.2 793147 794166 R identified by similarity to EGAD:13376; match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I complement(793147..794166) Neisseria meningitidis MC58 902880 NP_273808.1 CDS lepA NC_003112.2 794309 796102 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(794309..796102) Neisseria meningitidis MC58 902881 NP_273809.1 CDS pfs NC_003112.2 796246 796947 R identified by similarity to EGAD:109995; match to protein family HMM PF01048; match to protein family HMM TIGR01704; 5'-methylthioadenosine nucleosidase complement(796246..796947) Neisseria meningitidis MC58 902882 NP_273810.1 CDS pilT-2 NC_003112.2 797133 798245 D identified by similarity to EGAD:14316; match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility protein PilT 797133..798245 Neisseria meningitidis MC58 902883 NP_273811.1 CDS NMB0769 NC_003112.2 798279 799256 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 798279..799256 Neisseria meningitidis MC58 902884 NP_273812.1 CDS NMB0770 NC_003112.2 799260 799610 D identified by similarity to EGAD:38751; match to protein family HMM PF07238; type IV pilus assembly protein PilZ 799260..799610 Neisseria meningitidis MC58 902885 NP_273813.1 CDS NMB0771 NC_003112.2 799615 800394 D identified by similarity to EGAD:6599; match to protein family HMM PF01026; match to protein family HMM TIGR00010; hypothetical protein 799615..800394 Neisseria meningitidis MC58 902886 NP_273814.1 CDS NMB0772 NC_003112.2 800420 800635 D identified by similarity to EGAD:91807; match to protein family HMM PF03891; hypothetical protein 800420..800635 Neisseria meningitidis MC58 902887 NP_273815.1 CDS NMB0773 NC_003112.2 800736 801047 D identified by similarity to EGAD:50035; match to protein family HMM PF00462; match to protein family HMM TIGR00365; hypothetical protein 800736..801047 Neisseria meningitidis MC58 902888 NP_273816.1 CDS upp NC_003112.2 801153 801779 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 801153..801779 Neisseria meningitidis MC58 902889 NP_273817.1 CDS NMB0775 NC_003112.2 801802 802122 D hypothetical protein 801802..802122 Neisseria meningitidis MC58 902890 NP_273818.1 CDS NMB0776 NC_003112.2 802373 802792 D identified by similarity to GP:2580593; hypothetical protein 802373..802792 Neisseria meningitidis MC58 902891 NP_273819.1 CDS hemD NC_003112.2 802834 803574 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 802834..803574 Neisseria meningitidis MC58 902892 NP_273820.1 CDS NMB0778 NC_003112.2 803649 804923 D identified by similarity to EGAD:22018; match to protein family HMM PF04375; uroporphyrin-III C-methyltransferase HemX 803649..804923 Neisseria meningitidis MC58 902893 NP_273821.1 CDS NMB0779 NC_003112.2 804920 806143 D hypothetical protein 804920..806143 Neisseria meningitidis MC58 902894 NP_273822.1 CDS NMB0780 NC_003112.2 806176 806616 D hypothetical protein 806176..806616 Neisseria meningitidis MC58 902895 NP_273823.1 CDS hemE NC_003112.2 806770 807834 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 806770..807834 Neisseria meningitidis MC58 902896 NP_273824.1 CDS radA NC_003112.2 808020 809399 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 808020..809399 Neisseria meningitidis MC58 902897 NP_273825.1 CDS NMB0783 NC_003112.2 809675 810154 R identified by similarity to EGAD:157492; match to protein family HMM PF03625; hypothetical protein complement(809675..810154) Neisseria meningitidis MC58 902898 NP_273826.1 CDS NMB0784 NC_003112.2 810396 810755 R identified by similarity to EGAD:6573; match to protein family HMM PF00581; phage shock protein E complement(810396..810755) Neisseria meningitidis MC58 902899 NP_273827.1 CDS recB NC_003112.2 810794 814408 R identified by similarity to EGAD:28326; match to protein family HMM PF00580; match to protein family HMM TIGR00609; exodeoxyribonuclease V 135 KD polypeptide complement(810794..814408) Neisseria meningitidis MC58 902900 NP_273828.1 CDS NMB0786 NC_003112.2 814488 815396 R identified by similarity to EGAD:91404; match to protein family HMM PF04261; match to protein family HMM TIGR01413; hypothetical protein complement(814488..815396) Neisseria meningitidis MC58 902901 NP_273829.1 CDS NMB0787 NC_003112.2 815681 816508 D identified by similarity to EGAD:30720; match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 815681..816508 Neisseria meningitidis MC58 902902 NP_273830.1 CDS NMB0788 NC_003112.2 816552 817214 D identified by similarity to EGAD:90043; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 816552..817214 Neisseria meningitidis MC58 902903 NP_273831.1 CDS NMB0789 NC_003112.2 817224 817979 D identified by similarity to GP:666983; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 817224..817979 Neisseria meningitidis MC58 902904 NP_273832.1 CDS pgm NC_003112.2 817999 819381 R identified by similarity to EGAD:13620; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphoglucomutase complement(817999..819381) Neisseria meningitidis MC58 902905 NP_273833.1 CDS NMB0791 NC_003112.2 819548 820057 R identified by similarity to EGAD:28733; match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase complement(819548..820057) Neisseria meningitidis MC58 902906 NP_273834.1 CDS NMB0792 NC_003112.2 820176 821591 R identified by similarity to EGAD:29242; match to protein family HMM PF00939; match to protein family HMM TIGR00785; NadC family protein complement(820176..821591) Neisseria meningitidis MC58 902907 NP_273835.1 CDS NMB0793 NC_003112.2 821588 821797 R hypothetical protein complement(821588..821797) Neisseria meningitidis MC58 902908 NP_273836.1 CDS NMB0794 NC_003112.2 821822 822184 R hypothetical protein complement(821822..822184) Neisseria meningitidis MC58 902909 NP_273837.1 CDS pth NC_003112.2 822448 823026 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(822448..823026) Neisseria meningitidis MC58 902910 NP_273838.1 CDS NMB0796 NC_003112.2 823079 823357 R identified by similarity to EGAD:35606; match to protein family HMM PF03658; hypothetical protein complement(823079..823357) Neisseria meningitidis MC58 902911 NP_273839.1 CDS NMB0797 NC_003112.2 823350 823787 R identified by similarity to EGAD:34195; match to protein family HMM PF03364; hypothetical protein complement(823350..823787) Neisseria meningitidis MC58 902912 NP_273840.1 CDS ftsH NC_003112.2 824003 825970 R identified by similarity to EGAD:13183; match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; cell division protein FtsH complement(824003..825970) Neisseria meningitidis MC58 902913 NP_273841.1 CDS ftsJ NC_003112.2 826034 826654 R identified by similarity to EGAD:22071; match to protein family HMM PF01728; cell division protein FtsJ complement(826034..826654) Neisseria meningitidis MC58 902914 NP_273842.1 CDS NMB0800 NC_003112.2 826764 827048 D identified by similarity to EGAD:133408; match to protein family HMM PF01985; match to protein family HMM TIGR00253; hypothetical protein 826764..827048 Neisseria meningitidis MC58 902915 NP_273843.1 CDS hemB NC_003112.2 827231 828232 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 827231..828232 Neisseria meningitidis MC58 902916 NP_273844.1 CDS metB NC_003112.2 828295 829452 R identified by similarity to EGAD:109991; match to protein family HMM PF01053; cystathionine gamma-synthase complement(828295..829452) Neisseria meningitidis MC58 902917 NP_273845.1 CDS NMB0803 NC_003112.2 829644 830417 D similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase 829644..830417 Neisseria meningitidis MC58 902918 NP_273846.1 CDS NMB0804 NC_003112.2 830527 831192 D identified by similarity to EGAD:28277; match to protein family HMM PF00881; NAD(P)H nitroreductase 830527..831192 Neisseria meningitidis MC58 902919 NP_273847.1 CDS NMB0805 NC_003112.2 831333 832298 D identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase 831333..832298 Neisseria meningitidis MC58 902920 NP_273848.1 CDS NMB0806 NC_003112.2 832330 833088 R identified by similarity to EGAD:156128; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; hypothetical protein complement(832330..833088) Neisseria meningitidis MC58 902921 NP_273849.1 CDS ppnK NC_003112.2 833113 834003 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(833113..834003) Neisseria meningitidis MC58 902922 NP_273850.1 CDS NMB0808 NC_003112.2 834023 834589 R hypothetical protein complement(834023..834589) Neisseria meningitidis MC58 902923 NP_273851.1 CDS NMB0809 NC_003112.2 834640 835437 R identified by similarity to EGAD:91119; hypothetical protein complement(834640..835437) Neisseria meningitidis MC58 902924 NP_273852.1 CDS NMB0810 NC_003112.2 835492 836142 R identified by similarity to EGAD:17310; match to protein family HMM PF00440; TetR family transcriptional regulator complement(835492..836142) Neisseria meningitidis MC58 902925 NP_273853.1 CDS murB NC_003112.2 836154 837194 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(836154..837194) Neisseria meningitidis MC58 902926 NP_273854.1 CDS NMB0812 NC_003112.2 837238 838617 R NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein complement(837238..838617) Neisseria meningitidis MC58 902927 NP_273856.1 CDS hisZ NC_003112.2 838952 840103 D May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase 838952..840103 Neisseria meningitidis MC58 902929 NP_273857.1 CDS purA NC_003112.2 840201 841505 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 840201..841505 Neisseria meningitidis MC58 902930 NP_273859.1 CDS NMB0817 NC_003112.2 841970 842353 D hypothetical protein 841970..842353 Neisseria meningitidis MC58 902932 NP_273860.1 CDS NMB0818 NC_003112.2 842367 842777 D hypothetical protein 842367..842777 Neisseria meningitidis MC58 902933 NP_273861.1 CDS NMB0819 NC_003112.2 842894 843286 D hypothetical protein 842894..843286 Neisseria meningitidis MC58 902934 NP_273862.1 CDS NMB0820 NC_003112.2 843494 843886 D hypothetical protein 843494..843886 Neisseria meningitidis MC58 902935 NP_273864.1 CDS htpX NC_003112.2 844861 845904 R metalloprotease; heat shock protein HtpX complement(844861..845904) Neisseria meningitidis MC58 902937 NP_273865.1 CDS adk NC_003112.2 845916 846563 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 845916..846563 Neisseria meningitidis MC58 902938 NP_273866.1 CDS pyrF NC_003112.2 847089 847829 D OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 847089..847829 Neisseria meningitidis MC58 902939 NP_273867.1 CDS NMB0825 NC_003112.2 847884 848855 D identified by similarity to GP:1017464; match to protein family HMM PF00294; match to protein family HMM TIGR02198; ADP-heptose synthase 847884..848855 Neisseria meningitidis MC58 902940 NP_273868.1 CDS NMB0826 NC_003112.2 848892 850127 D identified by similarity to EGAD:38043; match to protein family HMM PF00145; match to protein family HMM TIGR00675; C-5 cytosine-specific DNA methylase 848892..850127 Neisseria meningitidis MC58 902941 NP_273870.1 CDS rfaD NC_003112.2 851289 852293 D identified by similarity to EGAD:22136; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR02197; ADP-L-glycero-D-manno-heptose-6-epimerase 851289..852293 Neisseria meningitidis MC58 902942 NP_273871.1 CDS hsdM NC_003112.2 852367 853911 D identified by similarity to GP:450688; match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497; type I restriction enzyme EcoR124II M protein 852367..853911 Neisseria meningitidis MC58 902943 NP_273872.1 CDS NMB0830 NC_003112.2 853908 854918 D identified by similarity to GP:4324608; hypothetical protein 853908..854918 Neisseria meningitidis MC58 902944 NP_273873.1 CDS prrC NC_003112.2 856315 857457 D identified by similarity to EGAD:6689; anticodon nuclease 856315..857457 Neisseria meningitidis MC58 902946 NP_273874.1 CDS NMB0833 NC_003112.2 857454 857840 D identified by similarity to EGAD:28865; type I restriction enzyme-like protein 857454..857840 Neisseria meningitidis MC58 902947 NP_273875.1 CDS NMB0834 NC_003112.2 857829 858794 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(857829..858794) Neisseria meningitidis MC58 902948 NP_273876.1 CDS NMB0835 NC_003112.2 858870 861635 D identified by similarity to EGAD:89363; match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348; type I restriction enzyme EcoR124II R protein 858870..861635 Neisseria meningitidis MC58 902949 NP_273877.1 CDS clpA NC_003112.2 861674 863983 R identified by similarity to EGAD:17776; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; ATP-dependent Clp protease, ATP-binding subunit ClpA complement(861674..863983) Neisseria meningitidis MC58 902950 NP_273878.1 CDS clpS NC_003112.2 863985 864287 R involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS complement(863985..864287) Neisseria meningitidis MC58 902951 NP_273879.1 CDS NMB0838 NC_003112.2 864530 864733 D identified by similarity to EGAD:97967; match to protein family HMM PF00313; cold-shock domain-contain protein 864530..864733 Neisseria meningitidis MC58 902952 NP_273880.1 CDS pmbA NC_003112.2 865030 866361 R identified by similarity to EGAD:28167; match to protein family HMM PF01523; pmbA protein complement(865030..866361) Neisseria meningitidis MC58 902953 NP_273881.1 CDS NMB0840 NC_003112.2 866484 867020 D identified by similarity to EGAD:28166; match to protein family HMM PF04751; hypothetical protein 866484..867020 Neisseria meningitidis MC58 902954 NP_273882.1 CDS NMB0841 NC_003112.2 867067 867783 D hypothetical protein 867067..867783 Neisseria meningitidis MC58 902955 NP_273883.1 CDS recJ NC_003112.2 867852 869552 D identified by similarity to GP:147550; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 867852..869552 Neisseria meningitidis MC58 902956 NP_273884.1 CDS pcnB NC_003112.2 869849 871210 D identified by similarity to GP:3650360; match to protein family HMM PF01743; match to protein family HMM TIGR01942; poly(A) polymerase 869849..871210 Neisseria meningitidis MC58 902957 NP_273885.1 CDS NMB0844 NC_003112.2 871383 871706 D hypothetical protein 871383..871706 Neisseria meningitidis MC58 902958 NP_273886.1 CDS NMB0845 NC_003112.2 871817 872770 R identified by similarity to EGAD:91454; match to protein family HMM PF02562; PhoH-related protein complement(871817..872770) Neisseria meningitidis MC58 902959 NP_273889.1 CDS NMB0848 NC_003112.2 874407 875111 D hypothetical protein 874407..875111 Neisseria meningitidis MC58 902962 NP_273890.1 CDS dcd NC_003112.2 875175 875741 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(875175..875741) Neisseria meningitidis MC58 902963 NP_273891.1 CDS NMB0850 NC_003112.2 875807 876223 R hypothetical protein complement(875807..876223) Neisseria meningitidis MC58 902964 NP_273892.1 CDS rdgC NC_003112.2 876285 877184 R Required for efficient pilin antigenic variation; recombination associated protein complement(876285..877184) Neisseria meningitidis MC58 902965 NP_273893.1 CDS engA NC_003112.2 877215 878672 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(877215..878672) Neisseria meningitidis MC58 902966 NP_273894.1 CDS NMB0853 NC_003112.2 878822 879451 R identified by similarity to EGAD:90623; match to protein family HMM PF07719; hypothetical protein complement(878822..879451) Neisseria meningitidis MC58 902967 NP_273895.1 CDS hisS NC_003112.2 879452 880747 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(879452..880747) Neisseria meningitidis MC58 902968 NP_273896.1 CDS NMB0855 NC_003112.2 880841 881497 R identified by similarity to GP:2909665; match to protein family HMM PF03412; bacteriocin resistance protein complement(880841..881497) Neisseria meningitidis MC58 902969 NP_273897.1 CDS NMB0856 NC_003112.2 881779 882246 R hypothetical protein complement(881779..882246) Neisseria meningitidis MC58 902970 NP_273898.1 CDS NMB0857 NC_003112.2 882303 882479 R hypothetical protein complement(882303..882479) Neisseria meningitidis MC58 902971 NP_273899.1 CDS NMB0858 NC_003112.2 882483 882683 R hypothetical protein complement(882483..882683) Neisseria meningitidis MC58 902972 NP_273902.1 CDS NMB0861 NC_003112.2 883468 884013 R hypothetical protein complement(883468..884013) Neisseria meningitidis MC58 902975 NP_273903.1 CDS NMB0862 NC_003112.2 884010 884129 R hypothetical protein complement(884010..884129) Neisseria meningitidis MC58 902976 NP_273905.1 CDS NMB0864 NC_003112.2 884714 885004 R hypothetical protein complement(884714..885004) Neisseria meningitidis MC58 902978 NP_273906.1 CDS NMB0865 NC_003112.2 885010 885483 R hypothetical protein complement(885010..885483) Neisseria meningitidis MC58 902979 NP_273907.1 CDS NMB0866 NC_003112.2 885526 886395 R hypothetical protein complement(885526..886395) Neisseria meningitidis MC58 902980 NP_273908.1 CDS NMB0867 NC_003112.2 886559 887482 D identified by similarity to EGAD:161394; match to protein family HMM PF00849; YabO/YceC/SfhB family protein 886559..887482 Neisseria meningitidis MC58 902981 NP_273909.1 CDS NMB0868 NC_003112.2 887560 888201 R identified by similarity to EGAD:162676; hypothetical protein complement(887560..888201) Neisseria meningitidis MC58 902982 NP_273910.1 CDS NMB0869 NC_003112.2 888256 889047 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(888256..889047) Neisseria meningitidis MC58 902983 NP_273911.1 CDS panB NC_003112.2 889540 890331 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 889540..890331 Neisseria meningitidis MC58 902986 NP_273912.1 CDS panC NC_003112.2 890454 891290 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 890454..891290 Neisseria meningitidis MC58 902987 NP_273913.1 CDS NMB0872 NC_003112.2 891454 893298 D identified by similarity to EGAD:30939; match to protein family HMM PF07719; hypothetical protein 891454..893298 Neisseria meningitidis MC58 902988 NP_273914.1 CDS lolB NC_003112.2 893438 894019 D Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 893438..894019 Neisseria meningitidis MC58 902989 NP_273915.1 CDS ipk NC_003112.2 894029 894874 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 894029..894874 Neisseria meningitidis MC58 902990 NP_273916.1 CDS prsA NC_003112.2 895296 896279 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 895296..896279 Neisseria meningitidis MC58 902994 NP_273917.1 CDS rplY NC_003112.2 896346 896918 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 896346..896918 Neisseria meningitidis MC58 902995 NP_273918.1 CDS NMB0877 NC_003112.2 897043 898212 R identified by similarity to EGAD:10529; match to protein family HMM PF00768; match to protein family HMM PF07943; penicillin-binding protein complement(897043..898212) Neisseria meningitidis MC58 902996 NP_273919.1 CDS ilvA NC_003112.2 898360 899886 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 898360..899886 Neisseria meningitidis MC58 902997 NP_273920.1 CDS cysA NC_003112.2 899943 901016 R identified by similarity to EGAD:20843; match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate ABC transporter ATP-binding protein complement(899943..901016) Neisseria meningitidis MC58 902998 NP_273921.1 CDS cysW NC_003112.2 901013 901873 R identified by similarity to EGAD:49750; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter permease complement(901013..901873) Neisseria meningitidis MC58 902999 NP_273922.1 CDS cysT NC_003112.2 902125 902961 R identified by similarity to EGAD:14734; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter permease complement(902125..902961) Neisseria meningitidis MC58 903000 NP_273923.1 CDS NMB0882 NC_003112.2 903252 903584 D hypothetical protein 903252..903584 Neisseria meningitidis MC58 903001 NP_273924.1 CDS NMB0883 NC_003112.2 903916 904425 D identified by similarity to EGAD:28959; match to protein family HMM PF04140; hypothetical protein 903916..904425 Neisseria meningitidis MC58 903002 NP_273925.1 CDS sodB NC_003112.2 904942 905529 R identified by similarity to EGAD:12983; match to protein family HMM PF00081; match to protein family HMM PF02777; superoxide dismutase complement(904942..905529) Neisseria meningitidis MC58 903003 NP_273926.1 CDS dnaB NC_003112.2 905693 907099 D unwinds double stranded DNA; replicative DNA helicase 905693..907099 Neisseria meningitidis MC58 903004 NP_273927.1 CDS fimT NC_003112.2 907408 908076 D identified by similarity to SP:P13253; match to protein family HMM PF07963; match to protein family HMM TIGR02532; fimbrial protein FimT 907408..908076 Neisseria meningitidis MC58 903005 NP_273928.1 CDS NMB0887 NC_003112.2 908094 908708 D identified by similarity to EGAD:38517; match to protein family HMM TIGR02523; match to protein family HMM TIGR02532; type IV pilus assembly protein PilV 908094..908708 Neisseria meningitidis MC58 903006 NP_273929.1 CDS NMB0888 NC_003112.2 908705 909646 D hypothetical protein 908705..909646 Neisseria meningitidis MC58 903007 NP_273930.1 CDS NMB0889 NC_003112.2 909625 910218 D hypothetical protein 909625..910218 Neisseria meningitidis MC58 903008 NP_273931.1 CDS NMB0890 NC_003112.2 910208 910696 D identified by similarity to SP:P35645; match to protein family HMM PF07963; match to protein family HMM TIGR02532; type IV pilin-like protein 910208..910696 Neisseria meningitidis MC58 903009 NP_273933.1 CDS NMB0892 NC_003112.2 912411 912833 R identified by similarity to EGAD:91802; match to protein family HMM PF03591; AzlC-like protein complement(912411..912833) Neisseria meningitidis MC58 903011 NP_273934.1 CDS dut NC_003112.2 913033 913485 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 913033..913485 Neisseria meningitidis MC58 903012 NP_273935.1 CDS NMB0894 NC_003112.2 913563 914750 D catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate; succinyldiaminopimelate transaminase 913563..914750 Neisseria meningitidis MC58 903013 NP_273936.1 CDS NMB0895 NC_003112.2 915013 915792 D identified by similarity to EGAD:17611; match to protein family HMM PF03883; hypothetical protein 915013..915792 Neisseria meningitidis MC58 903014 NP_273937.1 CDS NMB0897 NC_003112.2 917506 917886 D hypothetical protein 917506..917886 Neisseria meningitidis MC58 903018 NP_273940.1 CDS NMB0900 NC_003112.2 919659 920576 D hypothetical protein 919659..920576 Neisseria meningitidis MC58 903021 NP_273942.1 CDS NMB0902 NC_003112.2 920980 921171 R hypothetical protein complement(920980..921171) Neisseria meningitidis MC58 903023 NP_273943.1 CDS NMB0903 NC_003112.2 921174 921467 R hypothetical protein complement(921174..921467) Neisseria meningitidis MC58 903024 NP_273944.1 CDS NMB0904 NC_003112.2 921464 921724 R hypothetical protein complement(921464..921724) Neisseria meningitidis MC58 903025 NP_273945.1 CDS NMB0905 NC_003112.2 921759 921974 R hypothetical protein complement(921759..921974) Neisseria meningitidis MC58 903026 NP_273946.1 CDS NMB0906 NC_003112.2 922044 922898 R hypothetical protein complement(922044..922898) Neisseria meningitidis MC58 903027 NP_273947.1 CDS NMB0907 NC_003112.2 922923 923282 R hypothetical protein complement(922923..923282) Neisseria meningitidis MC58 903028 NP_273948.1 CDS NMB0908 NC_003112.2 923350 923550 R hypothetical protein complement(923350..923550) Neisseria meningitidis MC58 903029 NP_273949.1 CDS NMB0909 NC_003112.2 923794 924318 R hypothetical protein complement(923794..924318) Neisseria meningitidis MC58 903030 NP_273950.1 CDS NMB0910 NC_003112.2 924322 925038 R identified by similarity to EGAD:140942; match to protein family HMM PF00717; transcriptional regulator complement(924322..925038) Neisseria meningitidis MC58 903031 NP_273951.1 CDS NMB0911 NC_003112.2 925455 926420 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(925455..926420) Neisseria meningitidis MC58 903032 NP_273952.1 CDS NMB0912 NC_003112.2 926564 927190 D hypothetical protein 926564..927190 Neisseria meningitidis MC58 903033 NP_273953.1 CDS pemK NC_003112.2 927243 927590 R identified by similarity to GP:2688953; pemK protein complement(927243..927590) Neisseria meningitidis MC58 903034 NP_273954.1 CDS pemI NC_003112.2 927592 927828 R identified by similarity to EGAD:24580; match to protein family HMM PF04014; pemI protein complement(927592..927828) Neisseria meningitidis MC58 903035 NP_273955.1 CDS NMB0915 NC_003112.2 928187 928678 R hypothetical protein complement(928187..928678) Neisseria meningitidis MC58 903036 NP_273956.1 CDS NMB0916 NC_003112.2 928697 928837 R hypothetical protein complement(928697..928837) Neisseria meningitidis MC58 903037 NP_273957.1 CDS NMB0917 NC_003112.2 929116 929484 R identified by similarity to EGAD:69439; match to protein family HMM PF05012; match to protein family HMM TIGR01550; death-on-curing protein complement(929116..929484) Neisseria meningitidis MC58 903038 NP_273958.1 CDS NMB0918 NC_003112.2 929481 929612 R hypothetical protein complement(929481..929612) Neisseria meningitidis MC58 903039 NP_273959.1 CDS NMB0919 NC_003112.2 930008 930967 R identified by similarity to EGAD:5595; match to protein family HMM PF01609; IS1106 transposase complement(930008..930967) Neisseria meningitidis MC58 903040 NP_273960.1 CDS icd NC_003112.2 932130 934355 R identified by similarity to EGAD:40125; match to protein family HMM PF03971; match to protein family HMM TIGR00178; isocitrate dehydrogenase, NADP-dependent, monomeric type complement(932130..934355) Neisseria meningitidis MC58 903041 NP_273961.1 CDS NMB0921 NC_003112.2 934360 934560 R hypothetical protein complement(934360..934560) Neisseria meningitidis MC58 903042 NP_273962.1 CDS NMB0922 NC_003112.2 934788 935903 D identified by similarity to EGAD:154767; match to protein family HMM PF07922; alpha-2,3-sialyltransferase 934788..935903 Neisseria meningitidis MC58 903043 NP_273963.1 CDS NMB0923 NC_003112.2 936068 936526 R identified by similarity to EGAD:138762; match to protein family HMM PF01322; cytochrome c complement(936068..936526) Neisseria meningitidis MC58 903044 NP_273964.1 CDS NMB0924 NC_003112.2 936645 937466 D identified by similarity to EGAD:28429; match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 936645..937466 Neisseria meningitidis MC58 903045 NP_273965.1 CDS NMB0925 NC_003112.2 937517 937963 R identified by similarity to EGAD:21663; match to protein family HMM PF03061; acyl CoA thioester hydrolase complement(937517..937963) Neisseria meningitidis MC58 903046 YP_008920708.1 CDS NMB0926 NC_003112.2 939548 940222 R opacity protein complement(939548..940222) Neisseria meningitidis MC58 903047 NP_273966.1 CDS pip NC_003112.2 941878 942810 D identified by similarity to EGAD:23177; match to protein family HMM PF00561; match to protein family HMM TIGR01249; proline iminopeptidase 941878..942810 Neisseria meningitidis MC58 903048 NP_273967.1 CDS NMB0928 NC_003112.2 942867 944063 R hypothetical protein complement(942867..944063) Neisseria meningitidis MC58 903049 NP_273968.1 CDS dapA NC_003112.2 944072 944947 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(944072..944947) Neisseria meningitidis MC58 903050 NP_273969.1 CDS NMB0930 NC_003112.2 945407 946798 D identified by similarity to EGAD:36665; match to protein family HMM PF00860; match to protein family HMM TIGR00801; xanthine/uracil permease 945407..946798 Neisseria meningitidis MC58 903051 NP_273970.1 CDS NMB0931 NC_003112.2 946860 947612 R identified by similarity to EGAD:20604; match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; RNA methyltransferase complement(946860..947612) Neisseria meningitidis MC58 903052 NP_273971.1 CDS NMB0932 NC_003112.2 947679 948167 R identified by similarity to EGAD:45828; match to protein family HMM PF04306; hypothetical protein complement(947679..948167) Neisseria meningitidis MC58 903053 NP_273972.1 CDS NMB0933 NC_003112.2 948172 948891 R identified by similarity to EGAD:22440; match to protein family HMM PF00383; match to protein family HMM PF04994; cytidine and deoxycytidylate deaminase complement(948172..948891) Neisseria meningitidis MC58 903054 NP_273973.1 CDS miaA NC_003112.2 948895 949836 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(948895..949836) Neisseria meningitidis MC58 903055 YP_008920709.1 CDS NMB0935a NC_003112.2 950635 951783 D hypothetical protein 950635..951783 Neisseria meningitidis MC58 17925333 NP_273975.1 CDS efp NC_003112.2 951826 952386 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 951826..952386 Neisseria meningitidis MC58 903057 NP_273976.1 CDS NMB0938 NC_003112.2 952437 953273 R hypothetical protein complement(952437..953273) Neisseria meningitidis MC58 903058 NP_273977.1 CDS NMB0939 NC_003112.2 953390 953971 R identified by similarity to EGAD:148309; match to protein family HMM PF07021; match to protein family HMM TIGR02081; hypothetical protein complement(953390..953971) Neisseria meningitidis MC58 903059 NP_273978.1 CDS metX NC_003112.2 953968 955107 R Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase complement(953968..955107) Neisseria meningitidis MC58 903060 NP_273979.1 CDS rpmJ NC_003112.2 955669 955794 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(955669..955794) Neisseria meningitidis MC58 903061 NP_273980.1 CDS rpmE2 NC_003112.2 955794 956069 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(955794..956069) Neisseria meningitidis MC58 903062 NP_273981.1 CDS metF NC_003112.2 956269 957147 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 956269..957147 Neisseria meningitidis MC58 903063 NP_273982.1 CDS metH NC_003112.2 957285 959561 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 957285..959561 Neisseria meningitidis MC58 903064 NP_273984.1 CDS NMB0946 NC_003112.2 959840 960577 D identified by similarity to EGAD:48455; match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM TIGR02190; peroxiredoxin 2 family protein/glutaredoxin 959840..960577 Neisseria meningitidis MC58 903066 NP_273985.1 CDS NMB0947 NC_003112.2 960826 962229 D Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 960826..962229 Neisseria meningitidis MC58 903067 NP_273986.1 CDS sdhC NC_003112.2 962508 962885 D identified by similarity to GP:3273343; match to protein family HMM PF01127; succinate dehydrogenase, cytochrome b556 subunit 962508..962885 Neisseria meningitidis MC58 903068 NP_273987.1 CDS sdhD NC_003112.2 962879 963220 D identified by similarity to GP:3273344; succinate dehydrogenase, hydrophobic membrane anchor protein 962879..963220 Neisseria meningitidis MC58 903069 NP_273988.1 CDS sdhA NC_003112.2 963223 964986 D identified by similarity to GP:3273345; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; succinate dehydrogenase, flavoprotein subunit 963223..964986 Neisseria meningitidis MC58 903070 NP_273989.1 CDS sdhB NC_003112.2 965106 965813 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 965106..965813 Neisseria meningitidis MC58 903071 NP_273990.1 CDS NMB0952 NC_003112.2 965817 966065 D identified by similarity to EGAD:36673; match to protein family HMM PF03937; hypothetical protein 965817..966065 Neisseria meningitidis MC58 903072 NP_273991.1 CDS NMB0953 NC_003112.2 966062 966145 D hypothetical protein 966062..966145 Neisseria meningitidis MC58 903073 NP_273992.1 CDS gltA NC_003112.2 966177 967460 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 966177..967460 Neisseria meningitidis MC58 903074 NP_273993.1 CDS sucA NC_003112.2 967665 970493 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 967665..970493 Neisseria meningitidis MC58 903075 NP_273994.1 CDS sucB NC_003112.2 970593 971774 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 970593..971774 Neisseria meningitidis MC58 903076 NP_273995.1 CDS lpdA1 NC_003112.2 972139 973572 D E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 972139..973572 Neisseria meningitidis MC58 903077 NP_273996.1 CDS NMB0958 NC_003112.2 973697 973984 D hypothetical protein 973697..973984 Neisseria meningitidis MC58 903078 NP_273997.1 CDS sucC NC_003112.2 974083 975249 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 974083..975249 Neisseria meningitidis MC58 903079 NP_273998.1 CDS sucD NC_003112.2 975260 976150 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 975260..976150 Neisseria meningitidis MC58 903080 NP_273999.1 CDS funZ NC_003112.2 976710 978305 R identified by similarity to GP:3139107; funZ protein complement(976710..978305) Neisseria meningitidis MC58 903081 NP_274000.1 CDS uvrA NC_003112.2 978339 981188 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(978339..981188) Neisseria meningitidis MC58 903082 NP_274001.1 CDS NMB0963 NC_003112.2 981343 982140 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 981343..982140 Neisseria meningitidis MC58 903083 NP_274002.1 CDS NMB0964 NC_003112.2 983265 985541 R identified by similarity to GP:2114321; match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor complement(983265..985541) Neisseria meningitidis MC58 903084 NP_274003.1 CDS NMB0965 NC_003112.2 985599 985871 R hypothetical protein complement(985599..985871) Neisseria meningitidis MC58 903085 NP_274004.1 CDS pabA NC_003112.2 985963 986553 D TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 985963..986553 Neisseria meningitidis MC58 903086 NP_274005.1 CDS trpD NC_003112.2 986617 987675 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 986617..987675 Neisseria meningitidis MC58 903087 NP_274006.1 CDS NMB0968 NC_003112.2 987683 987772 D hypothetical protein 987683..987772 Neisseria meningitidis MC58 903088 YP_008920710.1 CDS NMB0970 NC_003112.2 988452 989486 D replication initiation factor 988452..989486 Neisseria meningitidis MC58 903090 NP_274008.1 CDS NMB0971 NC_003112.2 989531 989821 D hypothetical protein 989531..989821 Neisseria meningitidis MC58 903091 NP_274009.1 CDS NMB0972 NC_003112.2 989826 990023 D hypothetical protein 989826..990023 Neisseria meningitidis MC58 903092 NP_274010.1 CDS NMB0973 NC_003112.2 990031 990315 D hypothetical protein 990031..990315 Neisseria meningitidis MC58 903093 NP_274011.1 CDS NMB0974 NC_003112.2 990322 990600 D hypothetical protein 990322..990600 Neisseria meningitidis MC58 903094 NP_274012.1 CDS NMB0975 NC_003112.2 990728 991045 D hypothetical protein 990728..991045 Neisseria meningitidis MC58 903095 NP_274013.1 CDS NMB0976 NC_003112.2 991029 991424 D identified by similarity to GP:3758871; TspB-like protein 991029..991424 Neisseria meningitidis MC58 903096 NP_274014.1 CDS NMB0977 NC_003112.2 991714 992187 D identified by similarity to EGAD:90558; match to protein family HMM PF02525; modulator of drug activity B 991714..992187 Neisseria meningitidis MC58 903097 NP_274015.1 CDS pntB NC_003112.2 992395 993780 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(992395..993780) Neisseria meningitidis MC58 903098 NP_274016.1 CDS NMB0979 NC_003112.2 993860 994243 R hypothetical protein complement(993860..994243) Neisseria meningitidis MC58 903099 NP_274017.1 CDS pntA NC_003112.2 994247 995788 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(994247..995788) Neisseria meningitidis MC58 903100 NP_274018.1 CDS serB NC_003112.2 996078 996911 D identified by similarity to EGAD:8936; match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488; phosphoserine phosphatase 996078..996911 Neisseria meningitidis MC58 903101 NP_274019.1 CDS NMB0982 NC_003112.2 997056 998198 D identified by similarity to EGAD:47927; match to protein family HMM PF00654; chloride channel protein-related protein 997056..998198 Neisseria meningitidis MC58 903102 NP_274020.1 CDS purH NC_003112.2 998362 999942 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 998362..999942 Neisseria meningitidis MC58 903103 NP_274021.1 CDS NMB0985 NC_003112.2 1001560 1002057 D identified by similarity to EGAD:143986; match to protein family HMM PF06252; E16-like protein 1001560..1002057 Neisseria meningitidis MC58 903105 NP_274022.1 CDS NMB0986 NC_003112.2 1002035 1002466 D hypothetical protein 1002035..1002466 Neisseria meningitidis MC58 903106 NP_274023.1 CDS NMB0987 NC_003112.2 1002774 1003319 D identified by similarity to EGAD:21606; N-acetylmuramoyl-L-alanine amidase 1002774..1003319 Neisseria meningitidis MC58 903107 NP_274024.1 CDS NMB0988 NC_003112.2 1003316 1003519 D hypothetical protein 1003316..1003519 Neisseria meningitidis MC58 903108 NP_274025.1 CDS NMB0989 NC_003112.2 1003522 1003686 D hypothetical protein 1003522..1003686 Neisseria meningitidis MC58 903109 NP_274026.1 CDS NMB0990 NC_003112.2 1003897 1004301 D hypothetical protein 1003897..1004301 Neisseria meningitidis MC58 903110 NP_274027.1 CDS NMB0991 NC_003112.2 1004343 1005455 R identified by similarity to EGAD:5595; match to protein family HMM PF01609; IS1106 transposase complement(1004343..1005455) Neisseria meningitidis MC58 903111 NP_274028.1 CDS hsf NC_003112.2 1005589 1007364 R identified by similarity to EGAD:131908; match to protein family HMM PF03895; match to protein family HMM PF05662; adhesin complement(1005589..1007364) Neisseria meningitidis MC58 903112 NP_274029.1 CDS NMB0993 NC_003112.2 1009296 1009466 R identified by similarity to EGAD:30834; match to protein family HMM PF00301; rubredoxin complement(1009296..1009466) Neisseria meningitidis MC58 903115 NP_274030.1 CDS NMB0994 NC_003112.2 1010149 1011240 R identified by similarity to EGAD:38335; match to protein family HMM PF02771; acyl-CoA dehydrogenase complement(1010149..1011240) Neisseria meningitidis MC58 903120 NP_274031.2 CDS NMB0995 NC_003112.2 1011375 1011923 R identified by similarity to EGAD:40926; match to protein family HMM TIGR00778; macrophage infectivity potentiator-related protein complement(1011375..1011923) Neisseria meningitidis MC58 903124 NP_274032.1 CDS NMB0996 NC_003112.2 1012078 1012449 R hypothetical protein complement(1012078..1012449) Neisseria meningitidis MC58 903125 NP_274033.1 CDS dld NC_003112.2 1012744 1014435 R component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase complement(1012744..1014435) Neisseria meningitidis MC58 903128 NP_274034.1 CDS NMB0998 NC_003112.2 1014959 1018792 D identified by similarity to EGAD:156263; match to protein family HMM PF00037; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913; oxidoreductase 1014959..1018792 Neisseria meningitidis MC58 903129 NP_274035.1 CDS NMB0999 NC_003112.2 1018973 1019974 D identified by similarity to GP:3046395; match to protein family HMM PF01207; NifR3/SMM1 family protein 1018973..1019974 Neisseria meningitidis MC58 903134 NP_274037.1 CDS NMB1002 NC_003112.2 1023533 1024408 R hypothetical protein complement(1023533..1024408) Neisseria meningitidis MC58 903138 NP_274038.1 CDS NMB1003 NC_003112.2 1024453 1024749 R hypothetical protein complement(1024453..1024749) Neisseria meningitidis MC58 903139 NP_274039.1 CDS NMB1004 NC_003112.2 1024755 1025000 R hypothetical protein complement(1024755..1025000) Neisseria meningitidis MC58 903140 NP_274040.1 CDS NMB1005 NC_003112.2 1024993 1025217 R hypothetical protein complement(1024993..1025217) Neisseria meningitidis MC58 903141 NP_274042.1 CDS NMB1007 NC_003112.2 1025489 1025860 D identified by similarity to EGAD:6473; match to protein family HMM PF01381; transcriptional regulator 1025489..1025860 Neisseria meningitidis MC58 903144 NP_274043.1 CDS NMB1008 NC_003112.2 1025862 1026485 D hypothetical protein 1025862..1026485 Neisseria meningitidis MC58 903146 NP_274044.1 CDS NMB1009 NC_003112.2 1026478 1026672 D identified by similarity to EGAD:28463; hypothetical protein 1026478..1026672 Neisseria meningitidis MC58 903147 NP_274045.1 CDS NMB1010 NC_003112.2 1026696 1027259 D hypothetical protein 1026696..1027259 Neisseria meningitidis MC58 903148 NP_274046.1 CDS NMB1011 NC_003112.2 1027290 1028237 D hypothetical protein 1027290..1028237 Neisseria meningitidis MC58 903149 NP_274047.1 CDS NMB1012 NC_003112.2 1028322 1028825 D hypothetical protein 1028322..1028825 Neisseria meningitidis MC58 903150 NP_274050.1 CDS NMB1016 NC_003112.2 1031227 1031832 R identified by similarity to EGAD:28214; match to protein family HMM PF01713; hypothetical protein complement(1031227..1031832) Neisseria meningitidis MC58 903154 NP_274051.1 CDS sbp NC_003112.2 1032557 1033612 R identified by similarity to EGAD:18583; match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter substrate-binding protein complement(1032557..1033612) Neisseria meningitidis MC58 903155 NP_274052.1 CDS NMB1018 NC_003112.2 1033718 1034200 R identified by similarity to EGAD:48492; match to protein family HMM PF00583; hypothetical protein complement(1033718..1034200) Neisseria meningitidis MC58 903156 NP_274053.1 CDS purK NC_003112.2 1034247 1035383 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(1034247..1035383) Neisseria meningitidis MC58 903157 NP_274054.1 CDS NMB1020 NC_003112.2 1035380 1035925 R hypothetical protein complement(1035380..1035925) Neisseria meningitidis MC58 903158 NP_274055.1 CDS trpE NC_003112.2 1035922 1037397 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1035922..1037397) Neisseria meningitidis MC58 903159 NP_274056.1 CDS NMB1022 NC_003112.2 1037517 1038482 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(1037517..1038482) Neisseria meningitidis MC58 903160 NP_274057.1 CDS NMB1023 NC_003112.2 1038622 1039581 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1038622..1039581) Neisseria meningitidis MC58 903161 NP_274058.1 CDS NMB1024 NC_003112.2 1039674 1040540 R identified by similarity to EGAD:36674; match to protein family HMM PF01571; hypothetical protein complement(1039674..1040540) Neisseria meningitidis MC58 903162 NP_274059.1 CDS NMB1025 NC_003112.2 1040572 1040934 R identified by similarity to EGAD:132011; match to protein family HMM PF01042; hypothetical protein complement(1040572..1040934) Neisseria meningitidis MC58 903163 NP_274060.1 CDS NMB1026 NC_003112.2 1041009 1041488 D identified by similarity to EGAD:91370; match to protein family HMM PF04073; match to protein family HMM TIGR00011; hypothetical protein 1041009..1041488 Neisseria meningitidis MC58 903164 NP_274061.1 CDS NMB1027 NC_003112.2 1041511 1042233 D identified by similarity to EGAD:48808; dnaJ protein, truncation 1041511..1042233 Neisseria meningitidis MC58 903191 NP_274062.1 CDS NMB1028 NC_003112.2 1042235 1043110 D identified by similarity to EGAD:28370; hypothetical protein 1042235..1043110 Neisseria meningitidis MC58 903165 NP_274063.1 CDS aspA NC_003112.2 1043182 1044579 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(1043182..1044579) Neisseria meningitidis MC58 903166 NP_274064.1 CDS NMB1030 NC_003112.2 1045040 1045603 R identified by similarity to EGAD:89838; match to protein family HMM PF04264; hypothetical protein complement(1045040..1045603) Neisseria meningitidis MC58 903167 NP_274065.1 CDS leuB NC_003112.2 1045766 1046836 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(1045766..1046836) Neisseria meningitidis MC58 903168 NP_274066.1 CDS nlaIVR NC_003112.2 1046870 1047601 R identified by similarity to EGAD:15581; type II restriction enzyme NlaIV complement(1046870..1047601) Neisseria meningitidis MC58 903169 NP_274067.1 CDS NMB1033 NC_003112.2 1047617 1048888 R identified by similarity to EGAD:19644; match to protein family HMM PF00145; match to protein family HMM TIGR00675; modification methylase NlaIV complement(1047617..1048888) Neisseria meningitidis MC58 903170 NP_274068.1 CDS leuD NC_003112.2 1049063 1049704 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(1049063..1049704) Neisseria meningitidis MC58 903171 NP_274069.1 CDS NMB1035 NC_003112.2 1049766 1050020 R hypothetical protein complement(1049766..1050020) Neisseria meningitidis MC58 903172 NP_274070.1 CDS leuC NC_003112.2 1050117 1051526 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(1050117..1051526) Neisseria meningitidis MC58 903173 NP_274071.1 CDS gshA NC_003112.2 1051786 1053135 D identified by similarity to EGAD:41093; match to protein family HMM TIGR02049; glutamate--cysteine ligase 1051786..1053135 Neisseria meningitidis MC58 903174 NP_274072.1 CDS radC NC_003112.2 1053258 1053935 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1053258..1053935 Neisseria meningitidis MC58 903175 NP_274073.1 CDS NMB1039 NC_003112.2 1054008 1054733 D identified by similarity to EGAD:29365; match to protein family HMM PF02677; hypothetical protein 1054008..1054733 Neisseria meningitidis MC58 903176 NP_274074.1 CDS NMB1040 NC_003112.2 1054886 1056166 D hypothetical protein 1054886..1056166 Neisseria meningitidis MC58 903177 NP_274075.1 CDS NMB1041 NC_003112.2 1056171 1057349 D identified by similarity to EGAD:6528; GTP-binding protein 1056171..1057349 Neisseria meningitidis MC58 903190 NP_274076.1 CDS NMB1042 NC_003112.2 1057346 1059817 D identified by similarity to EGAD:135627; match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; cation transporter E1-E2 family ATPase 1057346..1059817 Neisseria meningitidis MC58 903178 NP_274078.1 CDS fpr-1 NC_003112.2 1060578 1061354 R identified by similarity to EGAD:21243; match to protein family HMM PF00175; ferredoxin--NADP reductase complement(1060578..1061354) Neisseria meningitidis MC58 903181 NP_274079.1 CDS NMB1045 NC_003112.2 1061542 1062336 R hypothetical protein complement(1061542..1062336) Neisseria meningitidis MC58 903182 NP_274080.1 CDS thrC NC_003112.2 1062382 1063791 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(1062382..1063791) Neisseria meningitidis MC58 903183 NP_274081.1 CDS NMB1047 NC_003112.2 1063864 1064235 R hypothetical protein complement(1063864..1064235) Neisseria meningitidis MC58 903184 NP_274082.1 CDS NMB1048 NC_003112.2 1064487 1065956 R hypothetical protein complement(1064487..1065956) Neisseria meningitidis MC58 903185 NP_274083.1 CDS NMB1049 NC_003112.2 1066212 1067126 D identified by similarity to EGAD:14640; match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator 1066212..1067126 Neisseria meningitidis MC58 903186 NP_274084.1 CDS NMB1050 NC_003112.2 1067585 1068550 R identified by similarity to EGAD:18338; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(1067585..1068550) Neisseria meningitidis MC58 903187 NP_274085.1 CDS NMB1051 NC_003112.2 1068672 1070582 R identified by similarity to EGAD:28306; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(1068672..1070582) Neisseria meningitidis MC58 903188 NP_274086.1 CDS dedA NC_003112.2 1070601 1071245 R identified by similarity to EGAD:14096; match to protein family HMM PF00597; dedA protein complement(1070601..1071245) Neisseria meningitidis MC58 903189 NP_274087.1 CDS opc NC_003112.2 1071409 1072227 R identified by similarity to GP:1177565; match to protein family HMM PF07239; class 5 outer membrane protein complement(1071409..1072227) Neisseria meningitidis MC58 903235 NP_274088.2 CDS NMB1054 NC_003112.2 1073023 1074045 R transposase complement(1073023..1074045) Neisseria meningitidis MC58 903179 NP_274089.1 CDS glyA NC_003112.2 1074262 1075512 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(1074262..1075512) Neisseria meningitidis MC58 903374 NP_274091.1 CDS ggt NC_003112.2 1075994 1077814 R identified by similarity to EGAD:161107; match to protein family HMM PF01019; match to protein family HMM TIGR00066; gamma-glutamyltranspeptidase complement(1075994..1077814) Neisseria meningitidis MC58 903474 NP_274092.1 CDS NMB1059 NC_003112.2 1078543 1078761 D identified by similarity to EGAD:89718; match to protein family HMM PF04325; hypothetical protein 1078543..1078761 Neisseria meningitidis MC58 903476 NP_274093.1 CDS fbp NC_003112.2 1078904 1079878 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(1078904..1079878) Neisseria meningitidis MC58 903477 NP_274094.1 CDS NMB1061 NC_003112.2 1080124 1080969 R identified by similarity to EGAD:17919; match to protein family HMM PF04378; hypothetical protein complement(1080124..1080969) Neisseria meningitidis MC58 903478 NP_274095.1 CDS NMB1062 NC_003112.2 1081046 1081648 R identified by similarity to EGAD:155868; match to protein family HMM PF02660; match to protein family HMM TIGR00023; hypothetical protein complement(1081046..1081648) Neisseria meningitidis MC58 903479 NP_274096.1 CDS folB NC_003112.2 1081704 1082060 D identified by similarity to EGAD:36572; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; dihydroneopterin aldolase 1081704..1082060 Neisseria meningitidis MC58 903480 NP_274097.1 CDS NMB1064 NC_003112.2 1082094 1082630 D identified by similarity to EGAD:45912; match to protein family HMM PF00293; hypothetical protein 1082094..1082630 Neisseria meningitidis MC58 903481 NP_274098.1 CDS crcB NC_003112.2 1083144 1083503 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1083144..1083503) Neisseria meningitidis MC58 903482 NP_274099.1 CDS NMB1066 NC_003112.2 1083532 1084212 R hypothetical protein complement(1083532..1084212) Neisseria meningitidis MC58 903483 NP_274100.1 CDS ftsK-1 NC_003112.2 1084377 1087421 D identified by similarity to EGAD:30442; match to protein family HMM PF01580; cell division protein FtsK 1084377..1087421 Neisseria meningitidis MC58 903485 NP_274101.1 CDS proA NC_003112.2 1087646 1088908 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1087646..1088908) Neisseria meningitidis MC58 903486 NP_274102.1 CDS proB NC_003112.2 1088921 1090030 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1088921..1090030) Neisseria meningitidis MC58 903487 NP_274103.1 CDS leuA NC_003112.2 1090515 1092068 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1090515..1092068 Neisseria meningitidis MC58 903489 NP_274104.1 CDS NMB1071 NC_003112.2 1092163 1092825 D identified by similarity to EGAD:7870; match to protein family HMM PF02810; match to protein family HMM TIGR02292; hypothetical protein 1092163..1092825 Neisseria meningitidis MC58 903490 NP_274105.1 CDS lgt NC_003112.2 1092908 1093759 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1092908..1093759) Neisseria meningitidis MC58 903491 NP_274106.1 CDS NMB1073 NC_003112.2 1093830 1094960 R identified by similarity to EGAD:22297; match to protein family HMM PF00246; hypothetical protein complement(1093830..1094960) Neisseria meningitidis MC58 903492 NP_274107.1 CDS argB NC_003112.2 1095130 1096026 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1095130..1096026 Neisseria meningitidis MC58 903493 NP_274108.1 CDS NMB1075 NC_003112.2 1097672 1098340 R identified by similarity to GP:2243021; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; hypothetical protein complement(1097672..1098340) Neisseria meningitidis MC58 903494 NP_274109.1 CDS NMB1076 NC_003112.2 1098337 1099005 R identified by similarity to EGAD:91757; DnaA regulatory inactivator Hda complement(1098337..1099005) Neisseria meningitidis MC58 903495 NP_274110.1 CDS NMB1077 NC_003112.2 1099110 1099661 R identified by similarity to EGAD:28455; ABC transporter ATP-binding protein complement(1099110..1099661) Neisseria meningitidis MC58 903145 NP_274113.1 CDS NMB1081 NC_003112.2 1101164 1103149 D identified by similarity to EGAD:143678; bacteriophage transposase 1101164..1103149 Neisseria meningitidis MC58 903498 NP_274115.1 CDS NMB1083 NC_003112.2 1103519 1104691 D identified by similarity to EGAD:28477; bacteriophage DNA transposition protein B 1103519..1104691 Neisseria meningitidis MC58 903500 NP_274116.1 CDS NMB1084 NC_003112.2 1104693 1105214 D hypothetical protein 1104693..1105214 Neisseria meningitidis MC58 903501 NP_274117.1 CDS NMB1085 NC_003112.2 1105357 1105902 D identified by similarity to EGAD:21606; N-acetylmuramoyl-L-alanine amidase 1105357..1105902 Neisseria meningitidis MC58 903502 YP_008920711.1 CDS NMB1083a NC_003112.2 1106105 1106269 D hypothetical protein 1106105..1106269 Neisseria meningitidis MC58 17925334 NP_274118.1 CDS NMB1086 NC_003112.2 1106272 1106508 D hypothetical protein 1106272..1106508 Neisseria meningitidis MC58 903503 NP_274120.1 CDS NMB1088 NC_003112.2 1107146 1107316 R identified by similarity to GP:3127075; match to protein family HMM PF07411; hypothetical protein complement(1107146..1107316) Neisseria meningitidis MC58 903505 NP_274121.1 CDS NMB1089 NC_003112.2 1107544 1107882 D hypothetical protein 1107544..1107882 Neisseria meningitidis MC58 903506 NP_274122.1 CDS NMB1090 NC_003112.2 1107894 1108160 D hypothetical protein 1107894..1108160 Neisseria meningitidis MC58 903508 NP_274123.1 CDS NMB1091 NC_003112.2 1108157 1108354 D hypothetical protein 1108157..1108354 Neisseria meningitidis MC58 903509 NP_274124.1 CDS NMB1092 NC_003112.2 1108357 1108863 D hypothetical protein 1108357..1108863 Neisseria meningitidis MC58 903510 NP_274125.1 CDS NMB1093 NC_003112.2 1108860 1109450 R hypothetical protein complement(1108860..1109450) Neisseria meningitidis MC58 903514 NP_274126.1 CDS NMB1094 NC_003112.2 1109535 1111085 D hypothetical protein 1109535..1111085 Neisseria meningitidis MC58 903515 NP_274127.1 CDS NMB1095 NC_003112.2 1111085 1112653 D identified by similarity to EGAD:28497; match to protein family HMM PF06074; hypothetical protein 1111085..1112653 Neisseria meningitidis MC58 903516 NP_274128.1 CDS NMB1096 NC_003112.2 1112640 1113935 D identified by similarity to EGAD:28498; match to protein family HMM PF04233; match to protein family HMM TIGR01641; hypothetical protein 1112640..1113935 Neisseria meningitidis MC58 903517 NP_274129.1 CDS NMB1098 NC_003112.2 1114691 1115752 D identified by similarity to EGAD:28500; I protein 1114691..1115752 Neisseria meningitidis MC58 903520 NP_274130.1 CDS NMB1099 NC_003112.2 1115840 1116805 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(1115840..1116805) Neisseria meningitidis MC58 903521 NP_274131.1 CDS NMB1100 NC_003112.2 1116833 1117315 D hypothetical protein 1116833..1117315 Neisseria meningitidis MC58 903522 NP_274132.1 CDS NMB1101 NC_003112.2 1117315 1117737 D identified by similarity to EGAD:28494; match to protein family HMM PF07030; hypothetical protein 1117315..1117737 Neisseria meningitidis MC58 903523 NP_274133.1 CDS NMB1102 NC_003112.2 1117784 1118377 D hypothetical protein 1117784..1118377 Neisseria meningitidis MC58 903524 NP_274134.1 CDS NMB1103 NC_003112.2 1118374 1118571 D hypothetical protein 1118374..1118571 Neisseria meningitidis MC58 903525 NP_274135.1 CDS NMB1104 NC_003112.2 1118574 1119983 D identified by similarity to EGAD:28506; match to protein family HMM PF06274; phage sheath protein 1118574..1119983 Neisseria meningitidis MC58 903526 NP_274136.1 CDS NMB1105 NC_003112.2 1120048 1120425 D hypothetical protein 1120048..1120425 Neisseria meningitidis MC58 903527 NP_274137.1 CDS NMB1106 NC_003112.2 1120429 1120794 D hypothetical protein 1120429..1120794 Neisseria meningitidis MC58 903528 NP_274138.1 CDS NMB1107 NC_003112.2 1121046 1121648 R hypothetical protein complement(1121046..1121648) Neisseria meningitidis MC58 903529 NP_274139.1 CDS NMB1108 NC_003112.2 1121818 1123974 D hypothetical protein 1121818..1123974 Neisseria meningitidis MC58 903530 NP_274140.1 CDS NMB1109 NC_003112.2 1123974 1125305 D identified by similarity to EGAD:28510; match to protein family HMM PF07157; phage virion protein 1123974..1125305 Neisseria meningitidis MC58 903531 NP_274141.1 CDS NMB1110 NC_003112.2 1125295 1126440 D identified by similarity to EGAD:94050; match to protein family HMM PF06893; tail protein, 43 kDa 1125295..1126440 Neisseria meningitidis MC58 903532 NP_274142.1 CDS NMB1111 NC_003112.2 1126437 1127105 D identified by similarity to EGAD:28503; match to protein family HMM PF06890; match to protein family HMM TIGR01644; baseplate assembly protein V 1126437..1127105 Neisseria meningitidis MC58 903533 NP_274143.1 CDS NMB1112 NC_003112.2 1127206 1127553 D identified by similarity to EGAD:28504; match to protein family HMM PF07409; hypothetical protein 1127206..1127553 Neisseria meningitidis MC58 903534 NP_274144.1 CDS NMB1114 NC_003112.2 1128618 1129178 D identified by similarity to EGAD:91160; hypothetical protein 1128618..1129178 Neisseria meningitidis MC58 903536 NP_274145.1 CDS NMB1115 NC_003112.2 1129189 1131162 D identified by similarity to EGAD:68685; match to protein family HMM PF07484; tail fiber protein 1129189..1131162 Neisseria meningitidis MC58 903537 NP_274147.2 CDS NMB1117 NC_003112.2 1132239 1132541 R hypothetical protein complement(1132239..1132541) Neisseria meningitidis MC58 903539 NP_274148.1 CDS NMB1118 NC_003112.2 1132513 1132800 R identified by similarity to EGAD:48708; match to protein family HMM PF04365; hypothetical protein complement(1132513..1132800) Neisseria meningitidis MC58 903540 NP_274149.1 CDS NMB1119 NC_003112.2 1132880 1133485 D identified by similarity to EGAD:28402; hypothetical protein 1132880..1133485 Neisseria meningitidis MC58 903541 NP_274150.1 CDS NMB1120 NC_003112.2 1133464 1133760 D hypothetical protein 1133464..1133760 Neisseria meningitidis MC58 903542 NP_274153.1 CDS NMB1124 NC_003112.2 1135662 1136309 R hypothetical protein complement(1135662..1136309) Neisseria meningitidis MC58 903545 NP_274154.1 CDS NMB1125 NC_003112.2 1136306 1136677 R hypothetical protein complement(1136306..1136677) Neisseria meningitidis MC58 903546 NP_274155.1 CDS NMB1126 NC_003112.2 1136684 1137355 R hypothetical protein complement(1136684..1137355) Neisseria meningitidis MC58 903547 NP_274156.1 CDS NMB1127 NC_003112.2 1137520 1138239 R identified by similarity to EGAD:6851; match to protein family HMM PF00106; short chain dehydrogenase complement(1137520..1138239) Neisseria meningitidis MC58 903548 NP_274157.1 CDS NMB1128 NC_003112.2 1138322 1139635 R identified by similarity to EGAD:97074; match to protein family HMM PF01593; hypothetical protein complement(1138322..1139635) Neisseria meningitidis MC58 903549 NP_274159.1 CDS NMB1130 NC_003112.2 1140033 1140905 R identified by similarity to EGAD:49612; match to protein family HMM PF00494; phytoene synthase complement(1140033..1140905) Neisseria meningitidis MC58 903551 NP_274160.1 CDS hscA NC_003112.2 1141076 1142938 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 1141076..1142938 Neisseria meningitidis MC58 903552 NP_274161.1 CDS NMB1132 NC_003112.2 1143015 1143671 D hypothetical protein 1143015..1143671 Neisseria meningitidis MC58 903553 NP_274162.1 CDS NMB1133 NC_003112.2 1143708 1144469 D identified by similarity to EGAD:1534; similarity to EGAD:91259; match to protein family HMM PF00023; hypothetical protein 1143708..1144469 Neisseria meningitidis MC58 903554 NP_274163.1 CDS fdx-1 NC_003112.2 1144524 1144865 D identified by similarity to EGAD:19142; match to protein family HMM PF00111; match to protein family HMM TIGR02007; ferredoxin, 2Fe-2S type 1144524..1144865 Neisseria meningitidis MC58 903555 NP_274164.1 CDS NMB1135 NC_003112.2 1145140 1145283 D hypothetical protein 1145140..1145283 Neisseria meningitidis MC58 903556 YP_008920712.1 CDS NMB1135a NC_003112.2 1145288 1145842 R amino acid permease complement(1145288..1145842) Neisseria meningitidis MC58 17925335 NP_274166.1 CDS NMB1137 NC_003112.2 1146055 1146252 D identified by similarity to GP:3046317; match to protein family HMM PF04384; hypothetical protein 1146055..1146252 Neisseria meningitidis MC58 903558 NP_274167.1 CDS NMB1138 NC_003112.2 1146320 1146721 R identified by similarity to EGAD:29941; match to protein family HMM PF01479; hypothetical protein complement(1146320..1146721) Neisseria meningitidis MC58 903559 NP_274168.1 CDS accA-1 NC_003112.2 1146933 1147892 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1146933..1147892 Neisseria meningitidis MC58 903560 YP_338291.1 CDS tilS-1 NC_003112.2 1147990 1149270 D identified by similarity to EGAD:90825; match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthetase 1147990..1149270 Neisseria meningitidis MC58 903561 NP_274169.2 CDS NMB1141 NC_003112.2 1149344 1150129 D identified by similarity to EGAD:107730; match to protein family HMM PF00588; RNA methyltransferase 1149344..1150129 Neisseria meningitidis MC58 903562 NP_274171.1 CDS NMB1143 NC_003112.2 1150585 1150950 D hypothetical protein 1150585..1150950 Neisseria meningitidis MC58 903564 NP_274172.1 CDS NMB1144 NC_003112.2 1150962 1151267 D hypothetical protein 1150962..1151267 Neisseria meningitidis MC58 903565 NP_274173.1 CDS mpl-1 NC_003112.2 1151329 1152705 D identified by similarity to EGAD:19891; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01081; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 1151329..1152705 Neisseria meningitidis MC58 903566 NP_274174.1 CDS bioB-1 NC_003112.2 1152912 1153964 D identified by similarity to EGAD:28044; match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthetase 1152912..1153964 Neisseria meningitidis MC58 903567 NP_274175.1 CDS NMB1147 NC_003112.2 1154042 1154677 R hypothetical protein complement(1154042..1154677) Neisseria meningitidis MC58 903568 NP_274177.1 CDS NMB1149 NC_003112.2 1154911 1155054 R hypothetical protein complement(1154911..1155054) Neisseria meningitidis MC58 903570 NP_274178.1 CDS ilvD-1 NC_003112.2 1155323 1157182 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(1155323..1157182) Neisseria meningitidis MC58 903571 NP_274179.1 CDS cysI-1 NC_003112.2 1157355 1159124 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(1157355..1159124) Neisseria meningitidis MC58 903572 NP_274180.1 CDS cysJ-1 NC_003112.2 1159151 1160965 R identified by similarity to EGAD:22695; match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF00667; match to protein family HMM TIGR01931; sulfite reductase (NADPH) flavoprotein, alpha component complement(1159151..1160965) Neisseria meningitidis MC58 903573 NP_274181.1 CDS cysN-1 NC_003112.2 1160962 1162248 R identified by similarity to EGAD:18882; match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM TIGR02034; sulfate adenylyltransferase, subunit 1 complement(1160962..1162248) Neisseria meningitidis MC58 903574 NP_274182.1 CDS cysD-1 NC_003112.2 1162287 1163210 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(1162287..1163210) Neisseria meningitidis MC58 903575 NP_274183.1 CDS cysH-1 NC_003112.2 1163248 1163988 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(1163248..1163988) Neisseria meningitidis MC58 903576 NP_274184.1 CDS cysG-1 NC_003112.2 1163999 1165450 R identified by similarity to EGAD:142433; match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470; siroheme synthase complement(1163999..1165450) Neisseria meningitidis MC58 903577 NP_274186.1 CDS NMB1158 NC_003112.2 1165747 1166403 R identified by similarity to EGAD:43078; match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit complement(1165747..1166403) Neisseria meningitidis MC58 903579 NP_274187.1 CDS NMB1159 NC_003112.2 1166467 1167357 D identified by similarity to GP:3449254; match to protein family HMM PF01256; match to protein family HMM TIGR00196; hypothetical protein 1166467..1167357 Neisseria meningitidis MC58 903580 NP_274189.1 CDS NMB1162 NC_003112.2 1167698 1168345 R hypothetical protein complement(1167698..1168345) Neisseria meningitidis MC58 903582 NP_274190.1 CDS NMB1163 NC_003112.2 1168342 1168713 R hypothetical protein complement(1168342..1168713) Neisseria meningitidis MC58 903583 NP_274191.1 CDS NMB1164 NC_003112.2 1168720 1169391 R hypothetical protein complement(1168720..1169391) Neisseria meningitidis MC58 903584 NP_274192.1 CDS NMB1165 NC_003112.2 1169556 1170275 R identified by similarity to EGAD:6851; match to protein family HMM PF00106; short chain dehydrogenase complement(1169556..1170275) Neisseria meningitidis MC58 903585 NP_274193.1 CDS NMB1166 NC_003112.2 1170358 1171671 R identified by similarity to EGAD:97074; match to protein family HMM PF01593; hypothetical protein complement(1170358..1171671) Neisseria meningitidis MC58 903586 NP_274195.1 CDS NMB1168 NC_003112.2 1172069 1172941 R identified by similarity to EGAD:49612; match to protein family HMM PF00494; phytoene synthase complement(1172069..1172941) Neisseria meningitidis MC58 903588 NP_274196.1 CDS hscA NC_003112.2 1173112 1174974 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 1173112..1174974 Neisseria meningitidis MC58 903589 NP_274197.1 CDS NMB1170 NC_003112.2 1175051 1175707 D hypothetical protein 1175051..1175707 Neisseria meningitidis MC58 903590 NP_274198.1 CDS NMB1171 NC_003112.2 1175744 1176505 D identified by similarity to EGAD:1534; similarity to EGAD:91259; match to protein family HMM PF00023; hypothetical protein 1175744..1176505 Neisseria meningitidis MC58 903591 NP_274199.1 CDS fdx-2 NC_003112.2 1176560 1176901 D identified by similarity to EGAD:19142; match to protein family HMM PF00111; match to protein family HMM TIGR02007; ferredoxin, 2Fe-2S type 1176560..1176901 Neisseria meningitidis MC58 903592 NP_274200.1 CDS NMB1173 NC_003112.2 1177176 1177319 D hypothetical protein 1177176..1177319 Neisseria meningitidis MC58 903593 NP_274201.1 CDS NMB1174 NC_003112.2 1177411 1178094 D hypothetical protein 1177411..1178094 Neisseria meningitidis MC58 903594 NP_274202.1 CDS NMB1175 NC_003112.2 1178091 1178288 D identified by similarity to GP:3046317; match to protein family HMM PF04384; hypothetical protein 1178091..1178288 Neisseria meningitidis MC58 903595 NP_274203.1 CDS NMB1176 NC_003112.2 1178356 1178757 R identified by similarity to EGAD:29941; match to protein family HMM PF01479; hypothetical protein complement(1178356..1178757) Neisseria meningitidis MC58 903596 NP_274204.1 CDS accA-2 NC_003112.2 1178969 1179928 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1178969..1179928 Neisseria meningitidis MC58 903597 YP_338292.1 CDS tilS-2 NC_003112.2 1180026 1181306 D identified by similarity to EGAD:90825; match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthetase 1180026..1181306 Neisseria meningitidis MC58 903598 NP_274205.2 CDS NMB1179 NC_003112.2 1181380 1182165 D identified by similarity to EGAD:107730; match to protein family HMM PF00588; RNA methyltransferase 1181380..1182165 Neisseria meningitidis MC58 903599 NP_274207.1 CDS NMB1181 NC_003112.2 1182621 1182986 D hypothetical protein 1182621..1182986 Neisseria meningitidis MC58 903601 NP_274208.1 CDS NMB1182 NC_003112.2 1182998 1183303 D hypothetical protein 1182998..1183303 Neisseria meningitidis MC58 903602 NP_274209.1 CDS mpl-2 NC_003112.2 1183365 1184741 D identified by similarity to EGAD:19891; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01081; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 1183365..1184741 Neisseria meningitidis MC58 903603 NP_274210.1 CDS bioB-2 NC_003112.2 1184948 1186000 D identified by similarity to EGAD:28044; match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthetase 1184948..1186000 Neisseria meningitidis MC58 903604 NP_274211.1 CDS NMB1185 NC_003112.2 1186078 1186713 R hypothetical protein complement(1186078..1186713) Neisseria meningitidis MC58 903605 NP_274213.1 CDS NMB1187 NC_003112.2 1186947 1187090 R hypothetical protein complement(1186947..1187090) Neisseria meningitidis MC58 903607 NP_274214.1 CDS ilvD-2 NC_003112.2 1187359 1189218 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(1187359..1189218) Neisseria meningitidis MC58 903608 NP_274215.1 CDS cysI-2 NC_003112.2 1189391 1191160 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(1189391..1191160) Neisseria meningitidis MC58 903609 NP_274216.1 CDS cysJ-2 NC_003112.2 1191187 1193001 R identified by similarity to EGAD:22695; match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF00667; match to protein family HMM TIGR01931; sulfite reductase (NADPH) flavoprotein, alpha component complement(1191187..1193001) Neisseria meningitidis MC58 903610 NP_274217.1 CDS cysN-2 NC_003112.2 1192998 1194284 R identified by similarity to EGAD:18882; match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM TIGR02034; sulfate adenylyltransferase, subunit 1 complement(1192998..1194284) Neisseria meningitidis MC58 903611 NP_274218.1 CDS cysD-2 NC_003112.2 1194323 1195246 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(1194323..1195246) Neisseria meningitidis MC58 903612 NP_274219.1 CDS cysH-2 NC_003112.2 1195284 1196024 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(1195284..1196024) Neisseria meningitidis MC58 903613 NP_274220.1 CDS cysG-2 NC_003112.2 1196035 1197486 R identified by similarity to EGAD:142433; match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470; siroheme synthase complement(1196035..1197486) Neisseria meningitidis MC58 903614 NP_274222.1 CDS NMB1196 NC_003112.2 1197783 1198439 R identified by similarity to EGAD:43078; match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit complement(1197783..1198439) Neisseria meningitidis MC58 903616 NP_274223.1 CDS NMB1197 NC_003112.2 1198503 1199393 D identified by similarity to GP:3449254; match to protein family HMM PF01256; match to protein family HMM TIGR00196; hypothetical protein 1198503..1199393 Neisseria meningitidis MC58 903617 NP_274224.1 CDS typA NC_003112.2 1199663 1201474 D identified by similarity to EGAD:24044; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA 1199663..1201474 Neisseria meningitidis MC58 903618 NP_274225.1 CDS NMB1200 NC_003112.2 1202310 1204685 D identified by similarity to EGAD:24912; match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; ribonuclease II family protein 1202310..1204685 Neisseria meningitidis MC58 903622 NP_274226.1 CDS guaB NC_003112.2 1205024 1206487 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(1205024..1206487) Neisseria meningitidis MC58 903623 NP_274227.1 CDS NMB1202 NC_003112.2 1206814 1207275 R hypothetical protein complement(1206814..1207275) Neisseria meningitidis MC58 903624 NP_274228.1 CDS glnD NC_003112.2 1207366 1209924 R identified by similarity to EGAD:8965; match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM TIGR01693; protein-PII uridylyltransferase complement(1207366..1209924) Neisseria meningitidis MC58 903625 NP_274229.1 CDS NMB1204 NC_003112.2 1209973 1210293 R identified by similarity to EGAD:10979; match to protein family HMM PF01381; transcriptional regulator complement(1209973..1210293) Neisseria meningitidis MC58 903626 NP_274230.1 CDS NMB1205 NC_003112.2 1210318 1210464 R hypothetical protein complement(1210318..1210464) Neisseria meningitidis MC58 903627 NP_274231.1 CDS bfrB NC_003112.2 1210618 1211091 R identified by similarity to EGAD:98244; match to protein family HMM PF00210; match to protein family HMM TIGR00754; bacterioferritin B complement(1210618..1211091) Neisseria meningitidis MC58 903628 NP_274232.1 CDS bfrA NC_003112.2 1211119 1211583 R identified by similarity to EGAD:97939; match to protein family HMM PF00210; match to protein family HMM TIGR00754; bacterioferritin A complement(1211119..1211583) Neisseria meningitidis MC58 903629 NP_274235.1 CDS NMB1210 NC_003112.2 1212159 1212626 D identified by similarity to GP:551169; match to protein family HMM PF02794; toxin-activating protein 1212159..1212626 Neisseria meningitidis MC58 903632 NP_274236.1 CDS NMB1211 NC_003112.2 1212780 1213022 R hypothetical protein complement(1212780..1213022) Neisseria meningitidis MC58 903633 NP_274237.1 CDS NMB1212 NC_003112.2 1213019 1213357 R hypothetical protein complement(1213019..1213357) Neisseria meningitidis MC58 903634 NP_274238.1 CDS NMB1213 NC_003112.2 1213354 1213716 R lipoprotein complement(1213354..1213716) Neisseria meningitidis MC58 903635 NP_274239.1 CDS NMB1214 NC_003112.2 1213713 1220534 R identified by similarity to GP:2623258; match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01731; match to protein family HMM TIGR01901; hemagglutinin/hemolysin-like protein complement(1213713..1220534) Neisseria meningitidis MC58 903636 NP_274240.1 CDS NMB1215 NC_003112.2 1220694 1220852 R hypothetical protein complement(1220694..1220852) Neisseria meningitidis MC58 903637 NP_274241.1 CDS lipA NC_003112.2 1221044 1222027 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1221044..1222027) Neisseria meningitidis MC58 903638 NP_274242.2 CDS lipB NC_003112.2 1222020 1222643 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1222020..1222643) Neisseria meningitidis MC58 903639 NP_274243.1 CDS NMB1218 NC_003112.2 1222645 1222920 R identified by similarity to EGAD:17261; match to protein family HMM PF04359; hypothetical protein complement(1222645..1222920) Neisseria meningitidis MC58 903640 NP_274244.1 CDS NMB1219 NC_003112.2 1223105 1224175 D identified by similarity to EGAD:107342; match to protein family HMM PF01594; transporter 1223105..1224175 Neisseria meningitidis MC58 903641 NP_274245.1 CDS NMB1220 NC_003112.2 1224372 1225319 R identified by similarity to GP:2984585; match to protein family HMM PF01145; stomatin/Mec-2 family protein complement(1224372..1225319) Neisseria meningitidis MC58 903642 NP_274246.1 CDS NMB1221 NC_003112.2 1225334 1225741 R hypothetical protein complement(1225334..1225741) Neisseria meningitidis MC58 903643 NP_274247.1 CDS ung NC_003112.2 1225822 1226481 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1225822..1226481 Neisseria meningitidis MC58 903644 NP_274248.1 CDS NMB1224 NC_003112.2 1229189 1229590 R hypothetical protein complement(1229189..1229590) Neisseria meningitidis MC58 903646 NP_274249.1 CDS NMB1225 NC_003112.2 1229635 1230150 R hypothetical protein complement(1229635..1230150) Neisseria meningitidis MC58 903647 NP_274250.1 CDS NMB1226 NC_003112.2 1230616 1232538 R identified by similarity to EGAD:91449; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(1230616..1232538) Neisseria meningitidis MC58 903648 NP_274251.1 CDS NMB1227 NC_003112.2 1232615 1233010 R identified by similarity to EGAD:132841; match to protein family HMM PF04635; hypothetical protein complement(1232615..1233010) Neisseria meningitidis MC58 903649 NP_274252.1 CDS metM NC_003112.2 1233183 1234490 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1233183..1234490 Neisseria meningitidis MC58 903650 NP_274253.1 CDS NMB1229 NC_003112.2 1234483 1234917 D hypothetical protein 1234483..1234917 Neisseria meningitidis MC58 903651 NP_274254.1 CDS hupB NC_003112.2 1234976 1235245 R identified by similarity to EGAD:8583; match to protein family HMM PF00216; DNA-binding protein HU-beta complement(1234976..1235245) Neisseria meningitidis MC58 903652 NP_274255.1 CDS lon NC_003112.2 1235427 1237889 R identified by similarity to EGAD:18728; match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM TIGR00763; ATP-dependent protease La complement(1235427..1237889) Neisseria meningitidis MC58 903653 NP_274257.1 CDS recD NC_003112.2 1239271 1241016 R identified by similarity to GP:3063663; match to protein family HMM TIGR01447; exodeoxyribonuclease V subunit alpha complement(1239271..1241016) Neisseria meningitidis MC58 903655 NP_274258.1 CDS NMB1234 NC_003112.2 1241084 1241779 R identified by similarity to EGAD:28534; match to protein family HMM PF00005; match to protein family HMM TIGR02211; ABC transporter ATP-binding protein complement(1241084..1241779) Neisseria meningitidis MC58 903656 NP_274259.1 CDS NMB1235 NC_003112.2 1241772 1243019 R identified by similarity to EGAD:91112; match to protein family HMM PF02687; match to protein family HMM TIGR02212; hypothetical protein complement(1241772..1243019) Neisseria meningitidis MC58 903657 NP_274260.1 CDS NMB1236 NC_003112.2 1243224 1243502 D hypothetical protein 1243224..1243502 Neisseria meningitidis MC58 903658 NP_274261.1 CDS recR NC_003112.2 1243558 1244178 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(1243558..1244178) Neisseria meningitidis MC58 903659 NP_274262.1 CDS NMB1238 NC_003112.2 1244242 1245780 R identified by similarity to EGAD:91215; peptidyl-prolyl cis-trans isomerase-like protein complement(1244242..1245780) Neisseria meningitidis MC58 903660 NP_274263.1 CDS NMB1239 NC_003112.2 1245840 1246214 R identified by similarity to EGAD:10818; match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein complement(1245840..1246214) Neisseria meningitidis MC58 903661 NP_274264.1 CDS NMB1240 NC_003112.2 1246364 1247992 D identified by similarity to EGAD:91449; match to protein family HMM PF00005; ABC transporter ATP-binding protein 1246364..1247992 Neisseria meningitidis MC58 903662 NP_274265.1 CDS cca NC_003112.2 1248064 1249317 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 1248064..1249317 Neisseria meningitidis MC58 903663 NP_274266.1 CDS NMB1242 NC_003112.2 1249540 1249848 D hypothetical protein 1249540..1249848 Neisseria meningitidis MC58 903664 NP_274267.1 CDS ruvB NC_003112.2 1249930 1250961 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1249930..1250961 Neisseria meningitidis MC58 903665 NP_274268.1 CDS rpe NC_003112.2 1250984 1251712 R identified by similarity to EGAD:7745; match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase complement(1250984..1251712) Neisseria meningitidis MC58 903666 NP_274270.1 CDS NMB1246 NC_003112.2 1252469 1253332 R identified by similarity to EGAD:49377; match to protein family HMM PF05673; hypothetical protein complement(1252469..1253332) Neisseria meningitidis MC58 903668 NP_274271.2 CDS ribE NC_003112.2 1253340 1253957 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1253340..1253957) Neisseria meningitidis MC58 903669 NP_274272.1 CDS NMB1249 NC_003112.2 1254939 1256711 D identified by similarity to EGAD:8121; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensory protein NarX 1254939..1256711 Neisseria meningitidis MC58 903671 NP_274273.1 CDS NMB1250 NC_003112.2 1256708 1257364 D identified by similarity to EGAD:9926; match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator 1256708..1257364 Neisseria meningitidis MC58 903672 NP_274274.1 CDS NMB1251 NC_003112.2 1257804 1258769 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(1257804..1258769) Neisseria meningitidis MC58 903673 NP_274275.1 CDS purM NC_003112.2 1258918 1259952 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(1258918..1259952) Neisseria meningitidis MC58 903674 NP_274276.1 CDS NMB1253 NC_003112.2 1260710 1261387 D hypothetical protein 1260710..1261387 Neisseria meningitidis MC58 903676 NP_274277.1 CDS ribA NC_003112.2 1261380 1261973 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1261380..1261973 Neisseria meningitidis MC58 903677 NP_274278.1 CDS ribA/B NC_003112.2 1263766 1264857 D bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein 1263766..1264857 Neisseria meningitidis MC58 903679 NP_274280.1 CDS NMB1258 NC_003112.2 1265774 1267084 R identified by similarity to EGAD:28582; match to protein family HMM PF00004; recombination factor protein RarA complement(1265774..1267084) Neisseria meningitidis MC58 903680 NP_274281.1 CDS NMB1259 NC_003112.2 1267622 1268587 D identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase 1267622..1268587 Neisseria meningitidis MC58 903681 NP_274282.1 CDS res NC_003112.2 1268664 1271603 R identified by similarity to EGAD:94080; match to protein family HMM PF04851; type III restriction-modification system EcoPI enzyme, subunit res complement(1268664..1271603) Neisseria meningitidis MC58 903682 NP_274283.1 CDS NMB1262 NC_003112.2 1273815 1274372 R identified by similarity to EGAD:14824; match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase complement(1273815..1274372) Neisseria meningitidis MC58 903684 NP_274284.1 CDS NMB1263 NC_003112.2 1274437 1275354 R identified by similarity to EGAD:156097; match to protein family HMM PF02492; match to protein family HMM PF07683; CobW-like protein complement(1274437..1275354) Neisseria meningitidis MC58 903685 NP_274285.1 CDS NMB1264 NC_003112.2 1275537 1275809 R identified by similarity to EGAD:43984; hypothetical protein complement(1275537..1275809) Neisseria meningitidis MC58 903686 NP_274286.1 CDS NMB1265 NC_003112.2 1275806 1276099 R identified by similarity to EGAD:44606; match to protein family HMM PF01909; hypothetical protein complement(1275806..1276099) Neisseria meningitidis MC58 903687 NP_274287.2 CDS NMB1266 NC_003112.2 1276144 1276737 R identified by similarity to EGAD:6546; zinc uptake regulation protein complement(1276144..1276737) Neisseria meningitidis MC58 903688 NP_274288.1 CDS NMB1267 NC_003112.2 1276691 1277146 R identified by similarity to EGAD:107998; match to protein family HMM PF01451; low molecular weight protein tyrosine-phosphatase complement(1276691..1277146) Neisseria meningitidis MC58 903689 NP_274289.1 CDS NMB1268 NC_003112.2 1277271 1278386 R identified by similarity to EGAD:30688; match to protein family HMM PF02595; match to protein family HMM TIGR00045; hypothetical protein complement(1277271..1278386) Neisseria meningitidis MC58 903690 NP_274290.1 CDS NMB1269 NC_003112.2 1278500 1279597 R hypothetical protein complement(1278500..1279597) Neisseria meningitidis MC58 903691 NP_274291.1 CDS NMB1270 NC_003112.2 1279679 1281310 R identified by similarity to EGAD:132853; hypothetical protein complement(1279679..1281310) Neisseria meningitidis MC58 903692 NP_274292.1 CDS NMB1271 NC_003112.2 1281410 1281622 R identified by similarity to EGAD:28925; match to protein family HMM PF00403; mercury transport periplasmic protein complement(1281410..1281622) Neisseria meningitidis MC58 903693 NP_274293.1 CDS NMB1272 NC_003112.2 1281660 1281803 R hypothetical protein complement(1281660..1281803) Neisseria meningitidis MC58 903694 NP_274294.1 CDS NMB1273 NC_003112.2 1282253 1283689 D identified by similarity to EGAD:38563; match to protein family HMM PF03062; alginate o-acetyltransferase AlgI 1282253..1283689 Neisseria meningitidis MC58 903695 NP_274295.1 CDS NMB1274 NC_003112.2 1283700 1284683 D hypothetical protein 1283700..1284683 Neisseria meningitidis MC58 903696 YP_008920713.1 CDS NMB1275 NC_003112.2 1284680 1285873 D hypothetical protein 1284680..1285873 Neisseria meningitidis MC58 903697 NP_274296.1 CDS fadD-1 NC_003112.2 1286160 1287713 D activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1286160..1287713 Neisseria meningitidis MC58 903698 NP_274297.1 CDS NMB1277 NC_003112.2 1287803 1289830 R identified by similarity to EGAD:28684; match to protein family HMM PF02028; match to protein family HMM TIGR00842; BCCT family transporter complement(1287803..1289830) Neisseria meningitidis MC58 903699 NP_274298.1 CDS gcr NC_003112.2 1290119 1292125 D identified by similarity to EGAD:142439; site-specific recombinase 1290119..1292125 Neisseria meningitidis MC58 903700 NP_274299.1 CDS NMB1279 NC_003112.2 1292248 1293357 R identified by similarity to EGAD:31033; match to protein family HMM TIGR02282; membrane-bound lytic murein transglycosylase B complement(1292248..1293357) Neisseria meningitidis MC58 903701 NP_274300.1 CDS NMB1280 NC_003112.2 1293559 1294986 R identified by similarity to EGAD:60787; match to protein family HMM PF00441; very long chain acyl-CoA dehydrogenase-related protein complement(1293559..1294986) Neisseria meningitidis MC58 903702 NP_274301.1 CDS mfd NC_003112.2 1295171 1299310 D identified by similarity to EGAD:28258; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 1295171..1299310 Neisseria meningitidis MC58 903703 NP_274302.1 CDS panD NC_003112.2 1299459 1299842 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 1299459..1299842 Neisseria meningitidis MC58 903704 NP_274303.1 CDS kdsA NC_003112.2 1299864 1300706 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1299864..1300706 Neisseria meningitidis MC58 903705 NP_274304.1 CDS NMB1284 NC_003112.2 1300721 1301161 D hypothetical protein 1300721..1301161 Neisseria meningitidis MC58 903706 NP_274305.1 CDS eno NC_003112.2 1301209 1302495 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1301209..1302495 Neisseria meningitidis MC58 903707 NP_274306.1 CDS NMB1286 NC_003112.2 1302509 1302787 D identified by similarity to EGAD:36588; match to protein family HMM PF04977; hypothetical protein 1302509..1302787 Neisseria meningitidis MC58 903708 NP_274307.1 CDS NMB1287 NC_003112.2 1302828 1303118 R identified by similarity to EGAD:28315; match to protein family HMM PF00111; ferredoxin complement(1302828..1303118) Neisseria meningitidis MC58 903709 NP_274308.2 CDS nrdB NC_003112.2 1303363 1304496 R B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta complement(1303363..1304496) Neisseria meningitidis MC58 903710 NP_274309.1 CDS NMB1289 NC_003112.2 1304557 1305744 R identified by similarity to GP:2961291; type II restriction enzyme complement(1304557..1305744) Neisseria meningitidis MC58 903711 NP_274310.1 CDS NMB1290 NC_003112.2 1305737 1306750 R identified by similarity to EGAD:7155; match to protein family HMM PF00145; match to protein family HMM TIGR00675; C-5 cytosine-specific DNA-methylase complement(1305737..1306750) Neisseria meningitidis MC58 903712 NP_274311.1 CDS nrdA NC_003112.2 1306808 1309087 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1306808..1309087) Neisseria meningitidis MC58 903713 NP_274312.1 CDS NMB1292 NC_003112.2 1309244 1309432 R hypothetical protein complement(1309244..1309432) Neisseria meningitidis MC58 903714 NP_274313.1 CDS NMB1293 NC_003112.2 1309601 1309927 D hypothetical protein 1309601..1309927 Neisseria meningitidis MC58 903715 NP_274314.1 CDS plsC NC_003112.2 1310238 1311005 R identified by similarity to EGAD:40820; match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1310238..1311005) Neisseria meningitidis MC58 903716 NP_274315.1 CDS mutM NC_003112.2 1311093 1311920 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(1311093..1311920) Neisseria meningitidis MC58 903717 NP_274316.1 CDS NMB1296 NC_003112.2 1311972 1312637 R hypothetical protein complement(1311972..1312637) Neisseria meningitidis MC58 903718 NP_274317.1 CDS NMB1297 NC_003112.2 1312816 1314792 D identified by similarity to EGAD:8903; match to protein family HMM PF01464; match to protein family HMM PF01476; match to protein family HMM PF06474; membrane-bound lytic murein transglycosylase D 1312816..1314792 Neisseria meningitidis MC58 903719 NP_274318.1 CDS rsuA NC_003112.2 1314860 1315552 D identified by similarity to EGAD:165416; match to protein family HMM PF00849; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A 1314860..1315552 Neisseria meningitidis MC58 903720 NP_274319.1 CDS cmk NC_003112.2 1317739 1318395 D identified by similarity to EGAD:10189; match to protein family HMM PF02224; match to protein family HMM TIGR00017; cytidylate kinase 1317739..1318395 Neisseria meningitidis MC58 903722 NP_274320.1 CDS rpsA NC_003112.2 1318551 1320236 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1318551..1320236 Neisseria meningitidis MC58 903723 NP_274321.1 CDS ihfB NC_003112.2 1320247 1320561 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1320247..1320561 Neisseria meningitidis MC58 903724 NP_274322.1 CDS NMB1303 NC_003112.2 1320912 1321319 R identified by similarity to EGAD:28824; match to protein family HMM PF00376; MerR family transcriptional regulator complement(1320912..1321319) Neisseria meningitidis MC58 903725 NP_274323.1 CDS NMB1304 NC_003112.2 1321440 1322576 D identified by similarity to EGAD:28823; match to protein family HMM PF00107; alcohol dehydrogenase 1321440..1322576 Neisseria meningitidis MC58 903726 NP_274324.1 CDS NMB1305 NC_003112.2 1322585 1323412 D identified by similarity to EGAD:28822; match to protein family HMM PF00756; esterase D 1322585..1323412 Neisseria meningitidis MC58 903727 NP_274325.1 CDS NMB1306 NC_003112.2 1323803 1324954 D identified by similarity to EGAD:30243; match to protein family HMM PF03969; hypothetical protein 1323803..1324954 Neisseria meningitidis MC58 903728 NP_274326.1 CDS ndk NC_003112.2 1325013 1325438 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1325013..1325438 Neisseria meningitidis MC58 903729 NP_274327.1 CDS NMB1308 NC_003112.2 1325581 1326675 D identified by similarity to EGAD:39884; match to protein family HMM PF04055; match to protein family HMM TIGR00048; hypothetical protein 1325581..1326675 Neisseria meningitidis MC58 903730 NP_274328.1 CDS NMB1309 NC_003112.2 1326678 1327439 D identified by similarity to EGAD:39885; match to protein family HMM PF00515; match to protein family HMM TIGR02521; fimbrial biogenesis and twitching motility protein 1326678..1327439 Neisseria meningitidis MC58 903731 NP_274329.1 CDS ispG NC_003112.2 1327455 1328720 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1327455..1328720 Neisseria meningitidis MC58 903732 NP_274331.1 CDS clpP NC_003112.2 1329163 1329693 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1329163..1329693) Neisseria meningitidis MC58 903734 NP_274332.1 CDS tig NC_003112.2 1329873 1331186 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(1329873..1331186) Neisseria meningitidis MC58 903735 NP_274333.1 CDS ftsK-2 NC_003112.2 1331391 1333829 R identified by similarity to EGAD:30442; match to protein family HMM PF01580; cell division protein FtsK complement(1331391..1333829) Neisseria meningitidis MC58 903736 NP_274334.1 CDS uraA NC_003112.2 1334052 1335263 D identified by similarity to EGAD:28228; match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease 1334052..1335263 Neisseria meningitidis MC58 903737 YP_008920714.1 CDS NMB1317a NC_003112.2 1335315 1335797 R hypothetical protein complement(1335315..1335797) Neisseria meningitidis MC58 17925336 NP_274336.1 CDS NMB1317 NC_003112.2 1335903 1336307 D hypothetical protein 1335903..1336307 Neisseria meningitidis MC58 903739 NP_274337.1 CDS pssA NC_003112.2 1336381 1337127 D identified by similarity to EGAD:166539; match to protein family HMM PF01066; match to protein family HMM TIGR00473; CDP-diacylglycerol--serine O-phosphatidyltransferase 1336381..1337127 Neisseria meningitidis MC58 903740 NP_274339.1 CDS rplI NC_003112.2 1338126 1338578 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(1338126..1338578) Neisseria meningitidis MC58 903742 NP_274340.1 CDS rpsR NC_003112.2 1338595 1338825 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1338595..1338825) Neisseria meningitidis MC58 903743 NP_274341.1 CDS NMB1322 NC_003112.2 1338832 1339134 R identified by similarity to EGAD:22393; primosomal replication protein complement(1338832..1339134) Neisseria meningitidis MC58 903744 NP_274342.1 CDS rpsF NC_003112.2 1339135 1339503 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1339135..1339503) Neisseria meningitidis MC58 903745 NP_274343.1 CDS trxB NC_003112.2 1339659 1340609 R identified by similarity to EGAD:28163; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin reductase complement(1339659..1340609) Neisseria meningitidis MC58 903746 NP_274344.1 CDS NMB1325 NC_003112.2 1340748 1342910 D identified by similarity to EGAD:98230; match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; cation transporter E1-E2 family ATPase 1340748..1342910 Neisseria meningitidis MC58 903747 NP_274345.1 CDS uvrC NC_003112.2 1343007 1344860 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1343007..1344860 Neisseria meningitidis MC58 903748 NP_274346.1 CDS NMB1327 NC_003112.2 1345083 1346486 D identified by similarity to EGAD:91374; hypothetical protein 1345083..1346486 Neisseria meningitidis MC58 903749 NP_274347.1 CDS trmB NC_003112.2 1346608 1347324 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1346608..1347324 Neisseria meningitidis MC58 903750 NP_274349.1 CDS NMB1330 NC_003112.2 1347952 1348314 R hypothetical protein complement(1347952..1348314) Neisseria meningitidis MC58 903752 NP_274350.1 CDS uvrB NC_003112.2 1348427 1350454 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1348427..1350454) Neisseria meningitidis MC58 903753 NP_274351.1 CDS prc NC_003112.2 1350783 1352267 R identified by similarity to GP:555748; match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; carboxy-terminal peptidase complement(1350783..1352267) Neisseria meningitidis MC58 903754 NP_274352.1 CDS NMB1333 NC_003112.2 1352394 1354184 R identified by similarity to EGAD:27923; match to protein family HMM PF01551; hypothetical protein complement(1352394..1354184) Neisseria meningitidis MC58 903755 NP_274353.1 CDS NMB1334 NC_003112.2 1354276 1354512 D hypothetical protein 1354276..1354512 Neisseria meningitidis MC58 903756 NP_274354.1 CDS creA NC_003112.2 1354512 1355072 D identified by similarity to EGAD:7971; match to protein family HMM PF05981; creA protein 1354512..1355072 Neisseria meningitidis MC58 903757 NP_274355.1 CDS NMB1336 NC_003112.2 1355074 1355622 D identified by similarity to EGAD:36515; match to protein family HMM PF02622; hypothetical protein 1355074..1355622 Neisseria meningitidis MC58 903758 NP_274356.1 CDS NMB1337 NC_003112.2 1355615 1356070 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1355615..1356070 Neisseria meningitidis MC58 903759 NP_274357.1 CDS NMB1338 NC_003112.2 1356080 1356736 R identified by similarity to EGAD:91262; match to protein family HMM PF01557; isomerase complement(1356080..1356736) Neisseria meningitidis MC58 903760 NP_274358.1 CDS proS NC_003112.2 1356799 1358511 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(1356799..1358511) Neisseria meningitidis MC58 903761 NP_274360.1 CDS aceE NC_003112.2 1359205 1361868 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1359205..1361868 Neisseria meningitidis MC58 903763 NP_274361.1 CDS aceF NC_003112.2 1362017 1363624 D Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; dihydrolipoamide acetyltransferase 1362017..1363624 Neisseria meningitidis MC58 903764 NP_274362.1 CDS NMB1343 NC_003112.2 1363718 1364155 D hypothetical protein 1363718..1364155 Neisseria meningitidis MC58 903765 NP_274363.1 CDS lpdA2 NC_003112.2 1364173 1365957 D identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) 1364173..1365957 Neisseria meningitidis MC58 903766 NP_274364.1 CDS NMB1345 NC_003112.2 1366318 1367868 R hypothetical protein complement(1366318..1367868) Neisseria meningitidis MC58 903767 NP_274365.1 CDS suhB NC_003112.2 1370039 1370824 R identified by similarity to EGAD:15335; match to protein family HMM PF00459; extragenic suppressor protein SuhB complement(1370039..1370824) Neisseria meningitidis MC58 903769 NP_274366.1 CDS NMB1348 NC_003112.2 1371068 1371883 D identified by similarity to GP:3046324; match to protein family HMM PF00588; match to protein family HMM TIGR00050; RNA methylase 1371068..1371883 Neisseria meningitidis MC58 903770 NP_274367.1 CDS NMB1349 NC_003112.2 1371944 1372801 D hypothetical protein 1371944..1372801 Neisseria meningitidis MC58 903771 NP_274368.1 CDS NMB1350 NC_003112.2 1373005 1373346 D hypothetical protein 1373005..1373346 Neisseria meningitidis MC58 903772 NP_274369.1 CDS NMB1351 NC_003112.2 1373694 1374950 D identified by similarity to GP:606223; match to protein family HMM PF01189; SUN-family protein 1373694..1374950 Neisseria meningitidis MC58 903773 NP_274370.1 CDS NMB1352 NC_003112.2 1375310 1375744 D hypothetical protein 1375310..1375744 Neisseria meningitidis MC58 903774 NP_274371.1 CDS NMB1353 NC_003112.2 1375792 1377135 R identified by similarity to EGAD:91347; match to protein family HMM PF00171; aldehyde dehydrogenase complement(1375792..1377135) Neisseria meningitidis MC58 903775 NP_274372.1 CDS NMB1354 NC_003112.2 1377140 1377793 R identified by similarity to EGAD:44279; match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein complement(1377140..1377793) Neisseria meningitidis MC58 903776 NP_274373.1 CDS gatC NC_003112.2 1377944 1378234 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1377944..1378234 Neisseria meningitidis MC58 903777 NP_274374.1 CDS gatA NC_003112.2 1378297 1379742 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1378297..1379742 Neisseria meningitidis MC58 903778 NP_274375.1 CDS NMB1357 NC_003112.2 1379739 1380671 D identified by similarity to EGAD:28126; match to protein family HMM PF04393; hypothetical protein 1379739..1380671 Neisseria meningitidis MC58 903779 NP_274376.1 CDS gatB NC_003112.2 1380714 1382144 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1380714..1382144 Neisseria meningitidis MC58 903780 NP_274377.1 CDS NMB1359 NC_003112.2 1382356 1383366 D identified by similarity to EGAD:21136; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF08030; CDP-6-deoxy-delta-3,4-glucoseen reductase 1382356..1383366 Neisseria meningitidis MC58 903781 NP_274378.1 CDS pdxH NC_003112.2 1383496 1384128 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1383496..1384128) Neisseria meningitidis MC58 903782 NP_274379.1 CDS NMB1361 NC_003112.2 1384350 1385402 D identified by similarity to GP:602963; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; hypothetical protein 1384350..1385402 Neisseria meningitidis MC58 903783 NP_274380.1 CDS NMB1362 NC_003112.2 1385471 1387012 R identified by similarity to EGAD:105396; match to protein family HMM PF07690; oxalate/formate antiporter complement(1385471..1387012) Neisseria meningitidis MC58 903784 NP_274381.1 CDS xseA NC_003112.2 1387305 1388660 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1387305..1388660) Neisseria meningitidis MC58 903785 NP_274382.1 CDS NMB1364 NC_003112.2 1388857 1389678 D identified by similarity to EGAD:105162; match to protein family HMM PF02540; match to protein family HMM TIGR00552; NH(3)-dependent NAD synthetase 1388857..1389678 Neisseria meningitidis MC58 903786 NP_274383.1 CDS NMB1365 NC_003112.2 1389748 1390221 R identified by similarity to EGAD:13856; match to protein family HMM PF03794; hypothetical protein complement(1389748..1390221) Neisseria meningitidis MC58 903787 NP_274384.1 CDS NMB1366 NC_003112.2 1390519 1390851 D identified by similarity to EGAD:28738; match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin I 1390519..1390851 Neisseria meningitidis MC58 903788 NP_274385.1 CDS NMB1367 NC_003112.2 1390904 1391968 R identified by similarity to EGAD:91631; hypothetical protein complement(1390904..1391968) Neisseria meningitidis MC58 903789 NP_274386.1 CDS NMB1368 NC_003112.2 1392179 1393567 D identified by similarity to EGAD:20681; match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase 1392179..1393567 Neisseria meningitidis MC58 903790 NP_274387.1 CDS NMB1369 NC_003112.2 1394056 1394610 R hypothetical protein complement(1394056..1394610) Neisseria meningitidis MC58 903791 NP_274388.1 CDS NMB1370 NC_003112.2 1394695 1395255 R hypothetical protein complement(1394695..1395255) Neisseria meningitidis MC58 903792 NP_274389.1 CDS argD NC_003112.2 1395599 1396795 D DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 1395599..1396795 Neisseria meningitidis MC58 903793 NP_274390.1 CDS clpX NC_003112.2 1396898 1398142 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1396898..1398142) Neisseria meningitidis MC58 903794 NP_274391.1 CDS rbfA NC_003112.2 1398333 1398704 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1398333..1398704 Neisseria meningitidis MC58 903795 NP_274392.1 CDS truB NC_003112.2 1398737 1399660 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1398737..1399660 Neisseria meningitidis MC58 903796 NP_274393.1 CDS lldD NC_003112.2 1404902 1406074 R identified by similarity to GP:4761135; match to protein family HMM PF01070; L-lactate dehydrogenase complement(1404902..1406074) Neisseria meningitidis MC58 903799 NP_274394.1 CDS NMB1378 NC_003112.2 1406365 1406811 D identified by similarity to EGAD:29015; match to protein family HMM PF02082; match to protein family HMM TIGR00738; match to protein family HMM TIGR02010; hypothetical protein 1406365..1406811 Neisseria meningitidis MC58 903800 NP_274395.1 CDS nifS NC_003112.2 1406840 1408054 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 1406840..1408054 Neisseria meningitidis MC58 903801 NP_274396.1 CDS NMB1380 NC_003112.2 1408318 1408704 D identified by similarity to EGAD:90661; match to protein family HMM PF01592; match to protein family HMM TIGR01999; scaffold protein 1408318..1408704 Neisseria meningitidis MC58 903802 NP_274397.1 CDS NMB1381 NC_003112.2 1408731 1409111 D identified by similarity to EGAD:91885; match to protein family HMM PF01521; match to protein family HMM TIGR00049; match to protein family HMM TIGR02011; HesB/YadR/YfhF family protein 1408731..1409111 Neisseria meningitidis MC58 903803 NP_274398.1 CDS NMB1382 NC_003112.2 1409071 1409292 R identified by similarity to EGAD:21493; match to protein family HMM PF03889; hypothetical protein complement(1409071..1409292) Neisseria meningitidis MC58 903804 NP_274399.1 CDS hscB NC_003112.2 1409374 1409874 D identified by similarity to EGAD:6265; match to protein family HMM PF00226; match to protein family HMM PF07743; match to protein family HMM TIGR00714; chaperone protein HscB 1409374..1409874 Neisseria meningitidis MC58 903805 NP_274400.1 CDS gyrA NC_003112.2 1409972 1412722 D identified by similarity to EGAD:21888; match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01063; DNA gyrase subunit A 1409972..1412722 Neisseria meningitidis MC58 903806 YP_338293.1 CDS NMB1386 NC_003112.2 1413341 1413796 D identified by similarity to GP:4200438; transposase 1413341..1413796 Neisseria meningitidis MC58 903808 NP_274401.1 CDS NMB1387 NC_003112.2 1414327 1414878 R hypothetical protein complement(1414327..1414878) Neisseria meningitidis MC58 903809 NP_274402.1 CDS pgi NC_003112.2 1414892 1416538 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1414892..1416538) Neisseria meningitidis MC58 903810 NP_274403.1 CDS NMB1389 NC_003112.2 1416659 1417507 R identified by similarity to EGAD:30099; match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR/YebK/YfhH family protein complement(1416659..1417507) Neisseria meningitidis MC58 903811 NP_274404.1 CDS glk NC_003112.2 1417557 1418543 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(1417557..1418543) Neisseria meningitidis MC58 903812 NP_274405.1 CDS NMB1391 NC_003112.2 1418524 1419219 R identified by similarity to EGAD:90181; match to protein family HMM TIGR01198; Sol/DevB family oxidoreductase complement(1418524..1419219) Neisseria meningitidis MC58 903813 NP_274406.1 CDS zwf NC_003112.2 1419499 1420944 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1419499..1420944) Neisseria meningitidis MC58 903814 NP_274407.1 CDS edd NC_003112.2 1421512 1423347 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1421512..1423347 Neisseria meningitidis MC58 903815 NP_274408.1 CDS eda NC_003112.2 1423528 1424166 D catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1423528..1424166 Neisseria meningitidis MC58 903816 NP_274409.1 CDS NMB1395 NC_003112.2 1424425 1425465 R identified by similarity to EGAD:21839; match to protein family HMM PF00107; alcohol dehydrogenase complement(1424425..1425465) Neisseria meningitidis MC58 903817 NP_274410.1 CDS mutY NC_003112.2 1425619 1426668 D identified by similarity to GP:3860539; match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 1425619..1426668 Neisseria meningitidis MC58 903818 NP_274411.1 CDS NMB1397 NC_003112.2 1426831 1427013 D hypothetical protein 1426831..1427013 Neisseria meningitidis MC58 903819 NP_274412.1 CDS sodC NC_003112.2 1427085 1427645 D identified by similarity to GP:2661420; match to protein family HMM PF00080; superoxide dismutase 1427085..1427645 Neisseria meningitidis MC58 903820 NP_274413.1 CDS NMB1399 NC_003112.2 1428210 1429184 R identified by similarity to EGAD:5595; match to protein family HMM PF01609; IS1106 transposase complement(1428210..1429184) Neisseria meningitidis MC58 903821 NP_274414.1 CDS NMB1400 NC_003112.2 1429441 1431669 R identified by similarity to GP:505571; match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01846; ABC transporter family protein complement(1429441..1431669) Neisseria meningitidis MC58 903822 NP_274416.1 CDS NMB1402 NC_003112.2 1433358 1433792 D hypothetical protein 1433358..1433792 Neisseria meningitidis MC58 903824 NP_274417.1 CDS NMB1403 NC_003112.2 1433833 1434024 D identified by similarity to EGAD:22554; FrpA/C-like protein 1433833..1434024 Neisseria meningitidis MC58 903825 NP_274418.1 CDS NMB1404 NC_003112.2 1434059 1434787 D hypothetical protein 1434059..1434787 Neisseria meningitidis MC58 903826 NP_274419.1 CDS NMB1405 NC_003112.2 1434801 1436003 D identified by similarity to EGAD:22554; FrpA/C-like protein 1434801..1436003 Neisseria meningitidis MC58 903827 NP_274423.1 CDS NMB1410 NC_003112.2 1439285 1439824 D hypothetical protein 1439285..1439824 Neisseria meningitidis MC58 903832 NP_274424.1 CDS NMB1411 NC_003112.2 1439995 1440648 R identified by similarity to EGAD:16254; IS1016C2 transposase complement(1439995..1440648) Neisseria meningitidis MC58 903833 NP_274425.1 CDS NMB1412 NC_003112.2 1441254 1442063 D identified by similarity to EGAD:20116; match to protein family HMM PF06901; FrpC operon protein 1441254..1442063 Neisseria meningitidis MC58 903834 NP_274426.1 CDS NMB1414 NC_003112.2 1442836 1443609 D identified by similarity to EGAD:20116; match to protein family HMM PF06901; FrpC operon protein 1442836..1443609 Neisseria meningitidis MC58 903836 NP_274427.1 CDS frpC NC_003112.2 1443626 1449115 D identified by similarity to EGAD:18289; match to protein family HMM PF00353; iron-regulated protein FrpC 1443626..1449115 Neisseria meningitidis MC58 903837 NP_274428.1 CDS pepN NC_003112.2 1449457 1452060 R identified by similarity to EGAD:22470; match to protein family HMM PF01433; match to protein family HMM TIGR02414; aminopeptidase complement(1449457..1452060) Neisseria meningitidis MC58 903838 NP_274429.1 CDS NMB1417 NC_003112.2 1452191 1452985 R identified by similarity to EGAD:89374; hypothetical protein complement(1452191..1452985) Neisseria meningitidis MC58 903839 NP_274430.1 CDS NMB1418 NC_003112.2 1453732 1454601 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1453732..1454601) Neisseria meningitidis MC58 903840 NP_274431.1 CDS ruvC NC_003112.2 1454652 1455188 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1454652..1455188) Neisseria meningitidis MC58 903841 NP_274432.1 CDS NMB1420 NC_003112.2 1455191 1455430 R identified by similarity to GP:2773326; match to protein family HMM PF02954; match to protein family HMM TIGR01199; DNA-binding protein Fis complement(1455191..1455430) Neisseria meningitidis MC58 903842 NP_274433.1 CDS NMB1421 NC_003112.2 1455460 1456470 R identified by similarity to EGAD:19890; match to protein family HMM PF01207; match to protein family HMM TIGR00737; nifR3 protein complement(1455460..1456470) Neisseria meningitidis MC58 903843 NP_274434.1 CDS NMB1422 NC_003112.2 1456836 1458209 D identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase 1456836..1458209 Neisseria meningitidis MC58 903844 NP_274435.1 CDS NMB1423 NC_003112.2 1458784 1459911 D identified by similarity to EGAD:156656; match to protein family HMM PF02661; hypothetical protein 1458784..1459911 Neisseria meningitidis MC58 903845 NP_274436.1 CDS NMB1424 NC_003112.2 1459941 1460969 D hypothetical protein 1459941..1460969 Neisseria meningitidis MC58 903846 NP_274437.1 CDS lysS NC_003112.2 1461087 1462598 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(1461087..1462598) Neisseria meningitidis MC58 903847 NP_274438.1 CDS NMB1426 NC_003112.2 1462753 1464006 R hypothetical protein complement(1462753..1464006) Neisseria meningitidis MC58 903848 NP_274439.1 CDS NMB1427 NC_003112.2 1464067 1464246 R hypothetical protein complement(1464067..1464246) Neisseria meningitidis MC58 903849 NP_274440.1 CDS NMB1428 NC_003112.2 1464464 1466260 D identified by similarity to GP:2760920; match to protein family HMM PF00557; aminopeptidase 1464464..1466260 Neisseria meningitidis MC58 903850 NP_274441.1 CDS porA NC_003112.2 1467069 1468247 R identified by similarity to GP:45187; match to protein family HMM PF00267; outer membrane protein PorA complement(1467069..1468247) Neisseria meningitidis MC58 903851 NP_274442.1 CDS greA NC_003112.2 1470526 1471002 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1470526..1471002) Neisseria meningitidis MC58 903852 NP_274444.1 CDS aroA NC_003112.2 1471398 1472699 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1471398..1472699 Neisseria meningitidis MC58 903854 NP_274445.1 CDS NMB1433 NC_003112.2 1472742 1473275 R identified by similarity to EGAD:37581; match to protein family HMM PF00877; hypothetical protein complement(1472742..1473275) Neisseria meningitidis MC58 903133 NP_274446.1 CDS NMB1434 NC_003112.2 1473483 1475009 R identified by similarity to EGAD:90768; match to protein family HMM PF00614; phopholipase D-family protein complement(1473483..1475009) Neisseria meningitidis MC58 903855 NP_274447.1 CDS NMB1435 NC_003112.2 1475121 1476527 R identified by similarity to EGAD:20464; match to protein family HMM PF07690; drug resistance translocase complement(1475121..1476527) Neisseria meningitidis MC58 903856 NP_274448.1 CDS NMB1436 NC_003112.2 1476812 1477591 D identified by similarity to EGAD:89510; match to protein family HMM PF02754; hypothetical protein 1476812..1477591 Neisseria meningitidis MC58 903857 NP_274449.1 CDS NMB1437 NC_003112.2 1477588 1478289 D identified by similarity to EGAD:89507; match to protein family HMM PF02589; hypothetical protein 1477588..1478289 Neisseria meningitidis MC58 903858 NP_274450.1 CDS NMB1438 NC_003112.2 1478286 1479740 D identified by similarity to EGAD:89509; match to protein family HMM PF00037; match to protein family HMM TIGR00273; hypothetical protein 1478286..1479740 Neisseria meningitidis MC58 903859 NP_274451.1 CDS purE NC_003112.2 1479923 1480408 R identified by similarity to EGAD:19627; match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit complement(1479923..1480408) Neisseria meningitidis MC58 903860 NP_274452.1 CDS NMB1440 NC_003112.2 1480456 1481169 R hypothetical protein complement(1480456..1481169) Neisseria meningitidis MC58 903861 NP_274453.1 CDS NMB1441 NC_003112.2 1481169 1481837 R identified by similarity to EGAD:48809; match to protein family HMM PF01596; O-methyltransferase complement(1481169..1481837) Neisseria meningitidis MC58 903862 YP_008920715.1 CDS NMB1441a NC_003112.2 1481848 1482033 R hypothetical protein complement(1481848..1482033) Neisseria meningitidis MC58 17925337 NP_274454.1 CDS mutL NC_003112.2 1482177 1484153 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1482177..1484153 Neisseria meningitidis MC58 903863 NP_274455.1 CDS dnaX NC_003112.2 1484248 1486362 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1484248..1486362 Neisseria meningitidis MC58 903132 NP_274456.1 CDS NMB1444 NC_003112.2 1486442 1486777 D identified by similarity to EGAD:14782; match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 1486442..1486777 Neisseria meningitidis MC58 903864 NP_274457.1 CDS recA NC_003112.2 1488548 1489594 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1488548..1489594) Neisseria meningitidis MC58 903865 NP_274458.1 CDS aroD NC_003112.2 1489848 1490612 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1489848..1490612 Neisseria meningitidis MC58 903866 NP_274459.1 CDS rep NC_003112.2 1490632 1492647 D identified by similarity to EGAD:29271; match to protein family HMM PF00580; match to protein family HMM TIGR01074; ATP-dependent DNA helicase 1490632..1492647 Neisseria meningitidis MC58 903867 NP_274460.1 CDS dinP NC_003112.2 1492816 1493772 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(1492816..1493772) Neisseria meningitidis MC58 903868 NP_274461.1 CDS fpr-2 NC_003112.2 1497279 1498058 D identified by similarity to EGAD:21243; match to protein family HMM PF00175; ferredoxin--NADP reductase 1497279..1498058 Neisseria meningitidis MC58 903870 NP_274462.1 CDS dnaQ-1 NC_003112.2 1498269 1499681 R identified by similarity to EGAD:157346; match to protein family HMM PF00929; match to protein family HMM TIGR00573; DNA polymerase III subunit epsilon complement(1498269..1499681) Neisseria meningitidis MC58 903871 NP_274463.1 CDS NMB1452 NC_003112.2 1500497 1501636 D identified by similarity to EGAD:90034; hypothetical protein 1500497..1501636 Neisseria meningitidis MC58 903874 NP_274464.1 CDS NMB1453 NC_003112.2 1501882 1502373 R hypothetical protein complement(1501882..1502373) Neisseria meningitidis MC58 903875 NP_274465.1 CDS NMB1454 NC_003112.2 1502433 1503929 R identified by similarity to EGAD:40049; match to protein family HMM PF00037; ferredoxin, 4Fe-4S type complement(1502433..1503929) Neisseria meningitidis MC58 903876 NP_274466.1 CDS NMB1455 NC_003112.2 1503994 1504113 R hypothetical protein complement(1503994..1504113) Neisseria meningitidis MC58 903877 NP_274468.1 CDS tktA NC_003112.2 1504457 1506436 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1504457..1506436 Neisseria meningitidis MC58 903879 NP_274469.1 CDS fumC NC_003112.2 1506585 1507973 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1506585..1507973 Neisseria meningitidis MC58 903880 NP_274470.1 CDS NMB1459 NC_003112.2 1508038 1508961 R identified by similarity to EGAD:133404; match to protein family HMM PF00892; hypothetical protein complement(1508038..1508961) Neisseria meningitidis MC58 903881 NP_274471.1 CDS ssb NC_003112.2 1509486 1510010 R identified by similarity to GP:1490785; match to protein family HMM PF00436; match to protein family HMM TIGR00621; ssDNA-binding protein complement(1509486..1510010) Neisseria meningitidis MC58 903882 NP_274472.1 CDS NMB1461 NC_003112.2 1510014 1511399 R identified by similarity to EGAD:91169; match to protein family HMM PF07690; drug resistance translocase complement(1510014..1511399) Neisseria meningitidis MC58 903883 NP_274473.1 CDS NMB1462 NC_003112.2 1511507 1512130 R identified by similarity to EGAD:107330; match to protein family HMM PF01464; transglycosylase complement(1511507..1512130) Neisseria meningitidis MC58 903884 NP_274474.1 CDS NMB1464 NC_003112.2 1513088 1513579 R identified by similarity to EGAD:37582; match to protein family HMM PF07605; hypothetical protein complement(1513088..1513579) Neisseria meningitidis MC58 903886 YP_008920716.1 CDS NMB1465 NC_003112.2 1514518 1515210 R hypothetical protein complement(1514518..1515210) Neisseria meningitidis MC58 903887 NP_274475.1 CDS NMB1466 NC_003112.2 1515677 1516408 D identified by similarity to EGAD:28010; match to protein family HMM PF04575; hypothetical protein 1515677..1516408 Neisseria meningitidis MC58 903888 NP_274476.1 CDS ppx NC_003112.2 1516525 1518033 D identified by similarity to GP:3452466; match to protein family HMM PF02541; exopolyphosphatase 1516525..1518033 Neisseria meningitidis MC58 903889 NP_274477.1 CDS NMB1468 NC_003112.2 1518242 1518565 R hypothetical protein complement(1518242..1518565) Neisseria meningitidis MC58 903890 NP_274478.1 CDS NMB1469 NC_003112.2 1518562 1518645 R hypothetical protein complement(1518562..1518645) Neisseria meningitidis MC58 903891 NP_274479.1 CDS NMB1470 NC_003112.2 1518885 1519430 R hypothetical protein complement(1518885..1519430) Neisseria meningitidis MC58 903892 NP_274480.1 CDS trpS NC_003112.2 1519499 1520509 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1519499..1520509) Neisseria meningitidis MC58 903893 NP_274481.1 CDS clpB NC_003112.2 1520770 1523349 D identified by similarity to EGAD:20010; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; clpB protein 1520770..1523349 Neisseria meningitidis MC58 903894 NP_274482.1 CDS NMB1473 NC_003112.2 1523436 1524650 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase complement(1523436..1524650) Neisseria meningitidis MC58 903895 NP_274483.1 CDS NMB1474 NC_003112.2 1524739 1524948 R identified by similarity to EGAD:19065; match to protein family HMM PF01361; match to protein family HMM TIGR00013; 4-oxalocrotonate tautomerase complement(1524739..1524948) Neisseria meningitidis MC58 903896 NP_274484.1 CDS NMB1475 NC_003112.2 1525293 1526099 D identified by similarity to EGAD:28416; hypothetical protein 1525293..1526099 Neisseria meningitidis MC58 903897 NP_274485.1 CDS gluD NC_003112.2 1526157 1527422 R identified by similarity to EGAD:20751; match to protein family HMM PF00208; match to protein family HMM PF02812; glutamate dehydrogenase complement(1526157..1527422) Neisseria meningitidis MC58 903898 NP_274486.1 CDS NMB1477 NC_003112.2 1527415 1527600 R hypothetical protein complement(1527415..1527600) Neisseria meningitidis MC58 903899 NP_274487.1 CDS recX NC_003112.2 1528598 1529059 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1528598..1529059 Neisseria meningitidis MC58 903901 NP_274489.1 CDS NMB1481 NC_003112.2 1529300 1529434 D hypothetical protein 1529300..1529434 Neisseria meningitidis MC58 903903 NP_274490.1 CDS NMB1482 NC_003112.2 1529447 1529929 D identified by similarity to EGAD:167992; match to protein family HMM PF03061; acyl CoA thioester hydrolase 1529447..1529929 Neisseria meningitidis MC58 903904 NP_274491.1 CDS NMB1483 NC_003112.2 1530290 1531537 R identified by similarity to EGAD:20336; match to protein family HMM PF01476; match to protein family HMM PF01551; lipoprotein NlpD complement(1530290..1531537) Neisseria meningitidis MC58 903905 NP_274492.1 CDS surE NC_003112.2 1531793 1532539 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(1531793..1532539) Neisseria meningitidis MC58 903906 NP_274493.1 CDS NMB1485 NC_003112.2 1532556 1534112 R identified by similarity to EGAD:91225; match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; hypothetical protein complement(1532556..1534112) Neisseria meningitidis MC58 903907 NP_274494.1 CDS NMB1486 NC_003112.2 1534161 1534301 R hypothetical protein complement(1534161..1534301) Neisseria meningitidis MC58 903908 NP_274495.1 CDS fimB NC_003112.2 1534480 1535268 R identified by similarity to EGAD:8572; fimbrial assembly protein complement(1534480..1535268) Neisseria meningitidis MC58 903909 NP_274496.1 CDS gabD NC_003112.2 1535377 1536810 R identified by similarity to EGAD:16804; match to protein family HMM PF00171; match to protein family HMM TIGR01780; succinate semialdehyde dehydrogenase complement(1535377..1536810) Neisseria meningitidis MC58 903910 NP_274497.1 CDS NMB1489 NC_003112.2 1537297 1537791 D hypothetical protein 1537297..1537791 Neisseria meningitidis MC58 903911 NP_274499.1 CDS NMB1491 NC_003112.2 1538734 1538823 R hypothetical protein complement(1538734..1538823) Neisseria meningitidis MC58 903913 NP_274500.1 CDS NMB1492 NC_003112.2 1538830 1538898 R hypothetical protein complement(1538830..1538898) Neisseria meningitidis MC58 903914 NP_274501.1 CDS cstA NC_003112.2 1538930 1541011 D identified by similarity to EGAD:8578; match to protein family HMM PF02554; carbon starvation protein A 1538930..1541011 Neisseria meningitidis MC58 903915 NP_274502.1 CDS NMB1494 NC_003112.2 1541001 1541195 D identified by similarity to EGAD:6530; match to protein family HMM PF04328; hypothetical protein 1541001..1541195 Neisseria meningitidis MC58 903916 NP_274503.1 CDS NMB1495 NC_003112.2 1541409 1541603 D hypothetical protein 1541409..1541603 Neisseria meningitidis MC58 903917 NP_274504.1 CDS NMB1496 NC_003112.2 1541711 1542271 D identified by similarity to EGAD:91124; match to protein family HMM PF00849; match to protein family HMM TIGR00093; hypothetical protein 1541711..1542271 Neisseria meningitidis MC58 903918 NP_274505.1 CDS NMB1497 NC_003112.2 1543272 1546037 D identified by similarity to EGAD:28219; match to protein family HMM PF00593; match to protein family HMM PF07715; TonB-dependent receptor 1543272..1546037 Neisseria meningitidis MC58 903921 NP_274506.1 CDS lysC NC_003112.2 1548041 1549258 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(1548041..1549258) Neisseria meningitidis MC58 903923 NP_274507.1 CDS rph NC_003112.2 1549458 1550186 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(1549458..1550186) Neisseria meningitidis MC58 903925 NP_274508.1 CDS NMB1500 NC_003112.2 1550268 1550732 R identified by similarity to EGAD:105670; match to protein family HMM PF00582; hypothetical protein complement(1550268..1550732) Neisseria meningitidis MC58 903931 NP_274509.1 CDS NMB1501 NC_003112.2 1550949 1551725 D identified by similarity to EGAD:21693; match to protein family HMM PF00899; HesA/MoeB/ThiF family protein 1550949..1551725 Neisseria meningitidis MC58 903934 NP_274510.1 CDS NMB1502 NC_003112.2 1551863 1552390 D hypothetical protein 1551863..1552390 Neisseria meningitidis MC58 903936 NP_274511.1 CDS NMB1503 NC_003112.2 1552646 1552855 D hypothetical protein 1552646..1552855 Neisseria meningitidis MC58 903942 NP_274512.1 CDS scpA NC_003112.2 1552744 1553598 D identified by similarity to EGAD:14314; match to protein family HMM PF02616; segregation and condensation protein A 1552744..1553598 Neisseria meningitidis MC58 903945 NP_274513.1 CDS pncB NC_003112.2 1553639 1554847 D catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1553639..1554847 Neisseria meningitidis MC58 903949 NP_274514.1 CDS argS NC_003112.2 1554939 1556657 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1554939..1556657 Neisseria meningitidis MC58 903953 NP_274516.1 CDS NMB1508 NC_003112.2 1557168 1558625 D hypothetical protein 1557168..1558625 Neisseria meningitidis MC58 903957 NP_274517.1 CDS NMB1509 NC_003112.2 1559636 1560382 R identified by similarity to EGAD:103138; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease complement(1559636..1560382) Neisseria meningitidis MC58 903968 NP_274518.1 CDS NMB1510 NC_003112.2 1560561 1561262 R identified by similarity to EGAD:28294; match to protein family HMM PF00565; thermonuclease complement(1560561..1561262) Neisseria meningitidis MC58 903976 NP_274519.1 CDS rpiA NC_003112.2 1561301 1561972 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(1561301..1561972) Neisseria meningitidis MC58 903979 NP_274520.1 CDS ispF NC_003112.2 1562049 1562531 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(1562049..1562531) Neisseria meningitidis MC58 903980 NP_274521.1 CDS ispD NC_003112.2 1562563 1563252 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(1562563..1563252) Neisseria meningitidis MC58 903982 NP_274522.1 CDS dnaQ-2 NC_003112.2 1563249 1563983 R identified by similarity to EGAD:21587; match to protein family HMM PF00929; match to protein family HMM TIGR00573; match to protein family HMM TIGR01406; DNA polymerase III subunit epsilon complement(1563249..1563983) Neisseria meningitidis MC58 903984 NP_274523.1 CDS NMB1515 NC_003112.2 1564139 1565449 R identified by similarity to EGAD:36624; match to protein family HMM PF07690; transporter complement(1564139..1565449) Neisseria meningitidis MC58 903986 NP_274524.1 CDS fixS NC_003112.2 1565439 1565627 R identified by similarity to GP:2398785; match to protein family HMM PF03597; match to protein family HMM TIGR00847; fixS protein complement(1565439..1565627) Neisseria meningitidis MC58 903990 NP_274525.1 CDS NMB1517 NC_003112.2 1565624 1565923 R hypothetical protein complement(1565624..1565923) Neisseria meningitidis MC58 903991 NP_274526.1 CDS ackA-2 NC_003112.2 1566274 1567470 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1566274..1567470 Neisseria meningitidis MC58 903996 NP_274527.1 CDS dipZ NC_003112.2 1567985 1569790 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(1567985..1569790) Neisseria meningitidis MC58 904002 YP_008920717.1 CDS NMB1521a NC_003112.2 1569917 1570387 D hypothetical protein 1569917..1570387 Neisseria meningitidis MC58 17925338 NP_274529.1 CDS NMB1521 NC_003112.2 1570460 1571287 R identified by similarity to GP:2113820; match to protein family HMM PF00494; phytoene synthase complement(1570460..1571287) Neisseria meningitidis MC58 904008 NP_274530.1 CDS slyD NC_003112.2 1571359 1571841 R identified by similarity to EGAD:17346; match to protein family HMM PF00254; FKBP-type peptidylprolyl isomerase complement(1571359..1571841) Neisseria meningitidis MC58 904012 NP_274531.1 CDS NMB1523 NC_003112.2 1572314 1572610 D hypothetical protein 1572314..1572610 Neisseria meningitidis MC58 904013 NP_274532.1 CDS NMB1524 NC_003112.2 1572720 1574087 D identified by similarity to EGAD:51447; match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase 1572720..1574087 Neisseria meningitidis MC58 904017 NP_274533.1 CDS smpB NC_003112.2 1576673 1577119 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1576673..1577119) Neisseria meningitidis MC58 904025 NP_274534.1 CDS rfaF NC_003112.2 1577174 1578184 R identified by similarity to EGAD:40767; match to protein family HMM PF01075; match to protein family HMM TIGR02195; ADP-heptose--LPS heptosyltransferase complement(1577174..1578184) Neisseria meningitidis MC58 904029 NP_274535.1 CDS NMB1528 NC_003112.2 1578582 1579391 R identified by similarity to EGAD:15497; match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589; methylated-DNA--protein-cysteine methyltransferase complement(1578582..1579391) Neisseria meningitidis MC58 904039 NP_274536.1 CDS NMB1529 NC_003112.2 1579635 1580450 D hypothetical protein 1579635..1580450 Neisseria meningitidis MC58 904043 NP_274537.1 CDS dapE NC_003112.2 1581121 1582266 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(1581121..1582266) Neisseria meningitidis MC58 904046 NP_274538.1 CDS NMB1531 NC_003112.2 1582379 1582999 R identified by similarity to EGAD:29187; hypothetical protein complement(1582379..1582999) Neisseria meningitidis MC58 904052 NP_274539.1 CDS NMB1532 NC_003112.2 1583033 1583542 R identified by similarity to EGAD:28880; match to protein family HMM PF03794; hypothetical protein complement(1583033..1583542) Neisseria meningitidis MC58 904056 NP_274540.1 CDS NMB1533 NC_003112.2 1583637 1584188 R identified by similarity to EGAD:7135; match to protein family HMM PF00127; outer membrane protein complement(1583637..1584188) Neisseria meningitidis MC58 904058 NP_274541.1 CDS NMB1534 NC_003112.2 1584185 1584325 R hypothetical protein complement(1584185..1584325) Neisseria meningitidis MC58 904062 YP_008920718.1 CDS NMB1536q NC_003112.2 1584469 1584891 R hypothetical protein complement(1584469..1584891) Neisseria meningitidis MC58 17925339 NP_274543.1 CDS secA NC_003112.2 1585022 1587772 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1585022..1587772 Neisseria meningitidis MC58 904068 NP_274544.1 CDS dnaG NC_003112.2 1587917 1589689 D synthesizes RNA primers at the replication forks; DNA primase 1587917..1589689 Neisseria meningitidis MC58 904069 NP_274545.1 CDS rpoD NC_003112.2 1589876 1591804 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1589876..1591804 Neisseria meningitidis MC58 904073 NP_274546.1 CDS NMB1539 NC_003112.2 1591951 1592958 D identified by similarity to EGAD:5595; match to protein family HMM PF01609; IS1106 transposase 1591951..1592958 Neisseria meningitidis MC58 904074 NP_274547.1 CDS lbpA NC_003112.2 1594478 1597309 R identified by similarity to EGAD:40813; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01776; match to protein family HMM TIGR01786; lactoferrin-binding protein A complement(1594478..1597309) Neisseria meningitidis MC58 904077 NP_274548.1 CDS lbpB NC_003112.2 1597306 1599519 R identified by similarity to GP:3582728; match to protein family HMM PF01298; lactoferrin-binding protein complement(1597306..1599519) Neisseria meningitidis MC58 904078 NP_274550.1 CDS NMB1543 NC_003112.2 1600909 1602123 D identified by similarity to GP:3402495; match to protein family HMM PF02486; hypothetical protein 1600909..1602123 Neisseria meningitidis MC58 904083 NP_274551.1 CDS NMB1544 NC_003112.2 1602135 1602446 D hypothetical protein 1602135..1602446 Neisseria meningitidis MC58 904085 NP_274552.1 CDS NMB1545 NC_003112.2 1602450 1602650 D hypothetical protein 1602450..1602650 Neisseria meningitidis MC58 904086 NP_274553.1 CDS NMB1546 NC_003112.2 1602833 1603117 D hypothetical protein 1602833..1603117 Neisseria meningitidis MC58 904087 NP_274554.1 CDS NMB1547 NC_003112.2 1603145 1603447 D hypothetical protein 1603145..1603447 Neisseria meningitidis MC58 904091 NP_274555.1 CDS NMB1548 NC_003112.2 1603779 1605425 D identified by similarity to GP:3758871; match to protein family HMM PF05616; tspB protein 1603779..1605425 Neisseria meningitidis MC58 904097 NP_274557.1 CDS NMB1550 NC_003112.2 1606370 1606654 D identified by similarity to EGAD:69712; hypothetical protein 1606370..1606654 Neisseria meningitidis MC58 904099 NP_274558.1 CDS NMB1551 NC_003112.2 1606655 1607758 D identified by similarity to GP:3402502; match to protein family HMM PF05707; hypothetical protein 1606655..1607758 Neisseria meningitidis MC58 904101 NP_274559.1 CDS pivNM-1A NC_003112.2 1608057 1609013 D identified by similarity to EGAD:138632; match to protein family HMM PF01548; match to protein family HMM PF02371; pilin gene inverting protein PivNM-1A 1608057..1609013 Neisseria meningitidis MC58 904103 NP_274560.1 CDS NMB1553 NC_003112.2 1611743 1612060 R identified by similarity to EGAD:137210; transposase, truncation complement(1611743..1612060) Neisseria meningitidis MC58 903131 NP_274561.1 CDS pyrG NC_003112.2 1612288 1613922 R CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(1612288..1613922) Neisseria meningitidis MC58 904105 NP_274562.1 CDS fadD-2 NC_003112.2 1614034 1615704 R identified by similarity to EGAD:141787; match to protein family HMM PF00501; long-chain-fatty-acid--CoA-ligase complement(1614034..1615704) Neisseria meningitidis MC58 904112 NP_274563.1 CDS mnmA NC_003112.2 1615775 1616878 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1615775..1616878) Neisseria meningitidis MC58 904116 NP_274564.1 CDS NMB1557 NC_003112.2 1617004 1617477 R identified by similarity to EGAD:156049; match to protein family HMM PF04314; hypothetical protein complement(1617004..1617477) Neisseria meningitidis MC58 904118 NP_274565.1 CDS dgkA NC_003112.2 1617770 1618153 R identified by similarity to EGAD:13380; match to protein family HMM PF01219; diacylglycerol kinase complement(1617770..1618153) Neisseria meningitidis MC58 904121 NP_274566.1 CDS gshB NC_003112.2 1618465 1619424 R catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase complement(1618465..1619424) Neisseria meningitidis MC58 904122 NP_274567.2 CDS glnS NC_003112.2 1619514 1621235 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(1619514..1621235) Neisseria meningitidis MC58 904126 NP_274568.1 CDS NMB1561 NC_003112.2 1621314 1622087 R identified by similarity to EGAD:102141; match to protein family HMM PF00455; DeoR family transcriptional regulator complement(1621314..1622087) Neisseria meningitidis MC58 904128 NP_274569.1 CDS NMB1562 NC_003112.2 1622130 1623032 R identified by similarity to EGAD:91752; match to protein family HMM PF03956; hypothetical protein complement(1622130..1623032) Neisseria meningitidis MC58 904132 NP_274570.1 CDS NMB1563 NC_003112.2 1623181 1623897 R identified by similarity to GP:2661693; match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator complement(1623181..1623897) Neisseria meningitidis MC58 904136 NP_274571.1 CDS NMB1564 NC_003112.2 1624466 1624888 R identified by similarity to EGAD:91663; match to protein family HMM PF02566; hypothetical protein complement(1624466..1624888) Neisseria meningitidis MC58 904138 NP_274572.1 CDS NMB1565 NC_003112.2 1625006 1625677 R hypothetical protein complement(1625006..1625677) Neisseria meningitidis MC58 904140 NP_274573.1 CDS purN NC_003112.2 1625693 1626319 R identified by similarity to GP:1562542; match to protein family HMM PF00551; match to protein family HMM TIGR00639; phosphoribosylglycinamide transformylase complement(1625693..1626319) Neisseria meningitidis MC58 904144 NP_274574.1 CDS NMB1567 NC_003112.2 1626426 1627244 R identified by similarity to GP:2231726; match to protein family HMM PF00254; match to protein family HMM PF01346; macrophage infectivity potentiator complement(1626426..1627244) Neisseria meningitidis MC58 904149 NP_274575.1 CDS NMB1568 NC_003112.2 1627503 1627943 R identified by similarity to GP:2984772; match to protein family HMM PF04364; DNA polymerase III subunit chi complement(1627503..1627943) Neisseria meningitidis MC58 904151 NP_274576.1 CDS NMB1570 NC_003112.2 1629582 1630697 D identified by similarity to EGAD:24062; match to protein family HMM PF03739; hypothetical protein 1629582..1630697 Neisseria meningitidis MC58 904153 NP_274577.1 CDS NMB1571 NC_003112.2 1630694 1631764 D identified by similarity to EGAD:28691; match to protein family HMM PF03739; hypothetical protein 1630694..1631764 Neisseria meningitidis MC58 904157 NP_274578.1 CDS acnB NC_003112.2 1631974 1634559 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 1631974..1634559 Neisseria meningitidis MC58 904159 NP_274579.1 CDS argF NC_003112.2 1634701 1635696 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 1634701..1635696 Neisseria meningitidis MC58 904168 NP_274580.1 CDS ilvC NC_003112.2 1635920 1636933 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(1635920..1636933) Neisseria meningitidis MC58 904172 NP_274581.1 CDS NMB1575 NC_003112.2 1637013 1637306 R identified by similarity to EGAD:108978; match to protein family HMM PF03992; hypothetical protein complement(1637013..1637306) Neisseria meningitidis MC58 904182 NP_274582.1 CDS ilvH NC_003112.2 1637373 1637864 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(1637373..1637864) Neisseria meningitidis MC58 904183 NP_274583.1 CDS ilvI NC_003112.2 1637875 1639602 R identified by similarity to EGAD:28577; match to protein family HMM PF00205; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase isozyme III large subunit complement(1637875..1639602) Neisseria meningitidis MC58 904184 NP_274584.1 CDS NMB1578 NC_003112.2 1640723 1641376 D identified by similarity to EGAD:156017; match to protein family HMM PF02630; hypothetical protein 1640723..1641376 Neisseria meningitidis MC58 904204 NP_274585.1 CDS hisG NC_003112.2 1641455 1642108 D short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 1641455..1642108 Neisseria meningitidis MC58 904212 NP_274586.1 CDS NMB1580 NC_003112.2 1642212 1643111 D hypothetical protein 1642212..1643111 Neisseria meningitidis MC58 904219 NP_274587.1 CDS hisD NC_003112.2 1643108 1644397 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1643108..1644397 Neisseria meningitidis MC58 904220 NP_274588.1 CDS hisC NC_003112.2 1644443 1645540 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1644443..1645540 Neisseria meningitidis MC58 904223 NP_274589.2 CDS hisB NC_003112.2 1645720 1646454 D catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1645720..1646454 Neisseria meningitidis MC58 904235 NP_274590.1 CDS NMB1584 NC_003112.2 1646549 1647418 D identified by similarity to EGAD:155484; match to protein family HMM PF03446; 3-hydroxyacid dehydrogenase 1646549..1647418 Neisseria meningitidis MC58 904236 NP_274591.1 CDS NMB1585 NC_003112.2 1647696 1648127 D identified by similarity to GP:2791909; match to protein family HMM PF01047; MarR family transcriptional regulator 1647696..1648127 Neisseria meningitidis MC58 904237 NP_274592.1 CDS NMB1586 NC_003112.2 1648138 1649004 D hypothetical protein 1648138..1649004 Neisseria meningitidis MC58 904238 NP_274593.1 CDS NMB1587 NC_003112.2 1649055 1650158 R SohB; periplasmic protein; member of the peptidase S49 family; protease complement(1649055..1650158) Neisseria meningitidis MC58 904239 NP_274594.1 CDS pgsA NC_003112.2 1650954 1651517 R identified by similarity to EGAD:19485; match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(1650954..1651517) Neisseria meningitidis MC58 904259 NP_274596.1 CDS NMB1590 NC_003112.2 1652378 1652713 R identified by similarity to EGAD:28075; match to protein family HMM PF02627; match to protein family HMM TIGR00778; hypothetical protein complement(1652378..1652713) Neisseria meningitidis MC58 904263 NP_274597.1 CDS mtrA NC_003112.2 1652842 1653747 D identified by similarity to EGAD:28074; match to protein family HMM PF00165; AraC family transcriptional regulator 1652842..1653747 Neisseria meningitidis MC58 904265 NP_274598.2 CDS NMB1592 NC_003112.2 1653809 1654297 R lipoprotein complement(1653809..1654297) Neisseria meningitidis MC58 904266 NP_274599.1 CDS NMB1593 NC_003112.2 1654483 1655346 D identified by similarity to EGAD:157019; match to protein family HMM PF00892; hypothetical protein 1654483..1655346 Neisseria meningitidis MC58 904269 NP_274600.1 CDS potD-3 NC_003112.2 1655387 1656517 R identified by similarity to EGAD:16715; match to protein family HMM PF01547; spermidine/putrescine ABC transporter substrate-binding protein complement(1655387..1656517) Neisseria meningitidis MC58 904275 NP_274601.1 CDS alaS NC_003112.2 1656722 1659346 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1656722..1659346 Neisseria meningitidis MC58 904276 NP_274603.1 CDS NMB1597 NC_003112.2 1659607 1660038 D hypothetical protein 1659607..1660038 Neisseria meningitidis MC58 904278 NP_274604.1 CDS NMB1598 NC_003112.2 1660132 1660323 D hypothetical protein 1660132..1660323 Neisseria meningitidis MC58 904279 NP_274606.1 CDS NMB1600 NC_003112.2 1660662 1660919 D hypothetical protein 1660662..1660919 Neisseria meningitidis MC58 904282 NP_274607.1 CDS NMB1601 NC_003112.2 1661113 1662120 D identified by similarity to EGAD:5595; match to protein family HMM PF01609; IS1106 transposase 1661113..1662120 Neisseria meningitidis MC58 904284 NP_274608.1 CDS NMB1602 NC_003112.2 1662032 1663150 R identified by similarity to GP:3005554; match to protein family HMM PF01548; match to protein family HMM PF02371; transposase complement(1662032..1663150) Neisseria meningitidis MC58 904293 NP_274609.1 CDS NMB1603 NC_003112.2 1663327 1664271 D identified by similarity to EGAD:19683; match to protein family HMM PF03595; potassium-tellurite ethidium and proflavin transporter 1663327..1664271 Neisseria meningitidis MC58 904294 NP_274610.1 CDS gpmA NC_003112.2 1664344 1665027 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(1664344..1665027) Neisseria meningitidis MC58 904297 NP_274611.1 CDS parC NC_003112.2 1665175 1667478 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1665175..1667478 Neisseria meningitidis MC58 904301 NP_274612.1 CDS NMB1606 NC_003112.2 1667498 1669015 D identified by similarity to EGAD:152602; match to protein family HMM PF00512; sensor histidine kinase 1667498..1669015 Neisseria meningitidis MC58 904302 NP_274613.1 CDS NMB1607 NC_003112.2 1669067 1669534 D identified by similarity to EGAD:21464; match to protein family HMM PF00072; match to protein family HMM PF02954; match to protein family HMM TIGR01199; sigma-54 dependent response regulator 1669067..1669534 Neisseria meningitidis MC58 904304 NP_274614.1 CDS NMB1608 NC_003112.2 1669638 1670390 D identified by similarity to EGAD:5782; match to protein family HMM PF04445; hypothetical protein 1669638..1670390 Neisseria meningitidis MC58 904305 YP_008920719.1 CDS NMB1608a NC_003112.2 1671436 1671642 R hypothetical protein complement(1671436..1671642) Neisseria meningitidis MC58 17925340 NP_274615.1 CDS NMB1609 NC_003112.2 1671729 1672898 R identified by similarity to EGAD:150275; match to protein family HMM PF01053; match to protein family HMM TIGR01325; O-succinylhomoserine sulfhydrolase complement(1671729..1672898) Neisseria meningitidis MC58 904307 NP_274616.1 CDS NMB1610 NC_003112.2 1673043 1673804 R hypothetical protein complement(1673043..1673804) Neisseria meningitidis MC58 904310 NP_274617.1 CDS NMB1611 NC_003112.2 1673904 1674155 D hypothetical protein 1673904..1674155 Neisseria meningitidis MC58 904311 NP_274618.1 CDS NMB1612 NC_003112.2 1674207 1675013 D identified by similarity to EGAD:8642; match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1674207..1675013 Neisseria meningitidis MC58 902102 NP_274619.1 CDS fumB NC_003112.2 1675320 1676843 D identified by similarity to SP:P14407; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase 1675320..1676843 Neisseria meningitidis MC58 904181 NP_274620.1 CDS trkA NC_003112.2 1676941 1678353 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1676941..1678353 Neisseria meningitidis MC58 904179 NP_274622.1 CDS thiD NC_003112.2 1679793 1680599 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1679793..1680599 Neisseria meningitidis MC58 904166 NP_274623.1 CDS NMB1617 NC_003112.2 1680649 1681518 R with TehA confers resistance to tellurite; tellurite resistance protein TehB complement(1680649..1681518) Neisseria meningitidis MC58 904150 NP_274624.1 CDS rnhA NC_003112.2 1681632 1682069 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1681632..1682069 Neisseria meningitidis MC58 904120 NP_274625.1 CDS NMB1619 NC_003112.2 1682927 1683331 D identified by similarity to EGAD:159687; match to protein family HMM PF01230; hypothetical protein 1682927..1683331 Neisseria meningitidis MC58 904072 NP_274626.1 CDS NMB1620 NC_003112.2 1683371 1684555 D identified by similarity to GP:3661475; match to protein family HMM PF02016; match to protein family HMM TIGR01409; hypothetical protein 1683371..1684555 Neisseria meningitidis MC58 904061 NP_274627.1 CDS gpxA NC_003112.2 1684618 1685151 R identified by similarity to EGAD:40773; match to protein family HMM PF00255; glutathione peroxidase complement(1684618..1685151) Neisseria meningitidis MC58 904057 NP_274628.1 CDS norB NC_003112.2 1685330 1687585 R identified by similarity to GP:2584871; nitric oxide reductase complement(1685330..1687585) Neisseria meningitidis MC58 904040 NP_274629.1 CDS pan1 NC_003112.2 1687956 1689128 D identified by similarity to EGAD:17111; match to protein family HMM PF00394; match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR02376; major anaerobically induced outer membrane protein 1687956..1689128 Neisseria meningitidis MC58 904036 NP_274630.1 CDS NMB1624 NC_003112.2 1689253 1690008 D hypothetical protein 1689253..1690008 Neisseria meningitidis MC58 904034 NP_274631.1 CDS pivNM-1B NC_003112.2 1690733 1691689 R identified by similarity to EGAD:138632; match to protein family HMM PF01548; match to protein family HMM PF02371; pilin gene inverting protein PivNM-1B complement(1690733..1691689) Neisseria meningitidis MC58 904033 NP_274632.1 CDS NMB1626 NC_003112.2 1691988 1693091 R identified by similarity to GP:3402502; match to protein family HMM PF05707; hypothetical protein complement(1691988..1693091) Neisseria meningitidis MC58 904031 NP_274633.1 CDS NMB1627 NC_003112.2 1693092 1693376 R identified by similarity to EGAD:69712; hypothetical protein complement(1693092..1693376) Neisseria meningitidis MC58 904011 NP_274634.1 CDS NMB1628 NC_003112.2 1693832 1695385 R identified by similarity to GP:3758871; match to protein family HMM PF05616; tspB protein complement(1693832..1695385) Neisseria meningitidis MC58 904007 NP_274635.1 CDS NMB1629 NC_003112.2 1695363 1695728 R hypothetical protein complement(1695363..1695728) Neisseria meningitidis MC58 904000 NP_274636.1 CDS NMB1630 NC_003112.2 1695793 1696095 R hypothetical protein complement(1695793..1696095) Neisseria meningitidis MC58 903998 NP_274637.1 CDS NMB1631 NC_003112.2 1696123 1696407 R hypothetical protein complement(1696123..1696407) Neisseria meningitidis MC58 903994 NP_274638.1 CDS NMB1632 NC_003112.2 1696590 1696790 R hypothetical protein complement(1696590..1696790) Neisseria meningitidis MC58 903972 NP_274639.1 CDS NMB1633 NC_003112.2 1696794 1697105 R hypothetical protein complement(1696794..1697105) Neisseria meningitidis MC58 903971 NP_274640.1 CDS NMB1634 NC_003112.2 1697126 1698334 R identified by similarity to GP:3402495; match to protein family HMM PF02486; hypothetical protein complement(1697126..1698334) Neisseria meningitidis MC58 903969 YP_008920720.1 CDS NMB1636 NC_003112.2 1700396 1701088 D opacity protein 1700396..1701088 Neisseria meningitidis MC58 903962 NP_274642.1 CDS NMB1637 NC_003112.2 1701289 1701846 R identified by similarity to EGAD:28537; match to protein family HMM PF00881; hypothetical protein complement(1701289..1701846) Neisseria meningitidis MC58 903959 NP_274643.1 CDS NMB1638 NC_003112.2 1701922 1703556 R identified by similarity to EGAD:20220; match to protein family HMM PF00884; match to protein family HMM PF08019; hypothetical protein complement(1701922..1703556) Neisseria meningitidis MC58 903951 NP_274644.1 CDS NMB1639 NC_003112.2 1703630 1703959 R hypothetical protein complement(1703630..1703959) Neisseria meningitidis MC58 903944 NP_274645.1 CDS serC NC_003112.2 1703959 1705065 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(1703959..1705065) Neisseria meningitidis MC58 903939 NP_274646.1 CDS NMB1641 NC_003112.2 1705412 1705861 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1705412..1705861 Neisseria meningitidis MC58 903938 NP_274647.1 CDS nusA NC_003112.2 1705889 1707391 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1705889..1707391 Neisseria meningitidis MC58 903935 NP_274648.1 CDS infB NC_003112.2 1707403 1710291 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1707403..1710291 Neisseria meningitidis MC58 903928 NP_274649.1 CDS NMB1644 NC_003112.2 1710453 1711793 R hypothetical protein complement(1710453..1711793) Neisseria meningitidis MC58 903472 NP_274650.1 CDS NMB1645 NC_003112.2 1711867 1713207 R hypothetical protein complement(1711867..1713207) Neisseria meningitidis MC58 903471 NP_274651.1 CDS NMB1646 NC_003112.2 1713350 1713976 D identified by similarity to EGAD:45741; match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin 1713350..1713976 Neisseria meningitidis MC58 903470 NP_274652.1 CDS NMB1647 NC_003112.2 1714040 1715458 R identified by similarity to EGAD:107412; match to protein family HMM PF01235; match to protein family HMM TIGR00835; amino acid symporter complement(1714040..1715458) Neisseria meningitidis MC58 903469 NP_274653.1 CDS NMB1648 NC_003112.2 1715785 1716513 D identified by similarity to EGAD:35798; match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 1715785..1716513 Neisseria meningitidis MC58 903468 NP_274654.1 CDS dsbB NC_003112.2 1716572 1717060 R identified by similarity to EGAD:8910; match to protein family HMM PF02600; disulfide bond formation protein B complement(1716572..1717060) Neisseria meningitidis MC58 903467 NP_274655.1 CDS lrp NC_003112.2 1717751 1718215 R identified by similarity to EGAD:134822; match to protein family HMM PF01037; leucine-responsive regulatory protein complement(1717751..1718215) Neisseria meningitidis MC58 903466 NP_274656.1 CDS alr NC_003112.2 1718540 1719598 D identified by similarity to EGAD:154434; match to protein family HMM PF00842; match to protein family HMM PF01168; match to protein family HMM TIGR00492; alanine racemase 1718540..1719598 Neisseria meningitidis MC58 903465 NP_274657.1 CDS NMB1652 NC_003112.2 1719662 1721017 R identified by similarity to EGAD:44268; match to protein family HMM PF05167; hypothetical protein complement(1719662..1721017) Neisseria meningitidis MC58 903464 NP_274658.1 CDS NMB1653 NC_003112.2 1721032 1721304 R ACT domain-containing protein; hypothetical protein complement(1721032..1721304) Neisseria meningitidis MC58 903463 NP_274659.1 CDS NMB1654 NC_003112.2 1721430 1722167 R identified by similarity to EGAD:107986; match to protein family HMM PF07661; hypothetical protein complement(1721430..1722167) Neisseria meningitidis MC58 903462 NP_274660.1 CDS NMB1655 NC_003112.2 1722448 1723359 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(1722448..1723359) Neisseria meningitidis MC58 903461 NP_274661.1 CDS NMB1656 NC_003112.2 1723492 1724085 D hypothetical protein 1723492..1724085 Neisseria meningitidis MC58 903460 NP_274662.1 CDS NMB1657 NC_003112.2 1724748 1725365 R identified by similarity to EGAD:36757; match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259; comE operon protein 1-like protein complement(1724748..1725365) Neisseria meningitidis MC58 903459 NP_274663.1 CDS coaBC NC_003112.2 1731103 1732287 D identified by similarity to EGAD:27976; match to protein family HMM PF02441; match to protein family HMM PF04127; match to protein family HMM TIGR00521; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase 1731103..1732287 Neisseria meningitidis MC58 903453 NP_274664.1 CDS spoT NC_003112.2 1732354 1734510 R identified by similarity to EGAD:12642; match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase complement(1732354..1734510) Neisseria meningitidis MC58 903452 NP_274665.1 CDS rpoZ NC_003112.2 1734602 1734808 R identified by similarity to EGAD:28791; match to protein family HMM PF01192; match to protein family HMM TIGR00690; DNA-directed RNA polymerase subunit omega complement(1734602..1734808) Neisseria meningitidis MC58 903451 NP_274666.1 CDS gmk NC_003112.2 1734867 1735484 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1734867..1735484) Neisseria meningitidis MC58 903450 NP_274667.1 CDS apt NC_003112.2 1735645 1736211 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1735645..1736211 Neisseria meningitidis MC58 903448 NP_274668.1 CDS NMB1663 NC_003112.2 1736257 1737045 R identified by similarity to EGAD:107896; match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hypothetical protein complement(1736257..1737045) Neisseria meningitidis MC58 903447 NP_274669.1 CDS NMB1664 NC_003112.2 1737370 1738725 D identified by similarity to EGAD:91300; match to protein family HMM PF01136; protease 1737370..1738725 Neisseria meningitidis MC58 903446 NP_274670.1 CDS NMB1665 NC_003112.2 1738905 1739291 R identified by similarity to EGAD:47695; match to protein family HMM PF01850; hypothetical protein complement(1738905..1739291) Neisseria meningitidis MC58 903445 NP_274671.1 CDS NMB1666 NC_003112.2 1739288 1739536 R hypothetical protein complement(1739288..1739536) Neisseria meningitidis MC58 903444 NP_274672.1 CDS NMB1667 NC_003112.2 1739893 1740099 R hypothetical protein complement(1739893..1740099) Neisseria meningitidis MC58 903443 NP_274673.1 CDS hmbR NC_003112.2 1740259 1742634 R identified by similarity to EGAD:131251; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01786; hemoglobin receptor complement(1740259..1742634) Neisseria meningitidis MC58 903442 NP_274674.1 CDS NMB1669 NC_003112.2 1742829 1743458 R identified by similarity to GP:3091146; match to protein family HMM PF01126; heme utilisation protein complement(1742829..1743458) Neisseria meningitidis MC58 903441 NP_274675.1 CDS NMB1670 NC_003112.2 1743744 1745255 D identified by similarity to EGAD:91640; match to protein family HMM PF04403; match to protein family HMM TIGR00155; PqiA family protein 1743744..1745255 Neisseria meningitidis MC58 903440 NP_274676.1 CDS pqiB NC_003112.2 1745248 1746909 D identified by similarity to EGAD:91619; match to protein family HMM PF02470; pqiB protein 1745248..1746909 Neisseria meningitidis MC58 903439 NP_274677.1 CDS NMB1672 NC_003112.2 1746909 1747427 D identified by similarity to EGAD:91019; match to protein family HMM PF03886; hypothetical protein 1746909..1747427 Neisseria meningitidis MC58 903438 NP_274678.1 CDS tag NC_003112.2 1747431 1747982 D identified by similarity to EGAD:128731; match to protein family HMM PF03352; DNA-3-methyladenine glycosylase I 1747431..1747982 Neisseria meningitidis MC58 903437 NP_274679.1 CDS NMB1674 NC_003112.2 1747972 1748613 D identified by similarity to EGAD:18113; match to protein family HMM PF00657; GDSL lipase 1747972..1748613 Neisseria meningitidis MC58 903436 NP_274680.1 CDS NMB1675 NC_003112.2 1748835 1749143 D hypothetical protein 1748835..1749143 Neisseria meningitidis MC58 903435 NP_274681.1 CDS NMB1677 NC_003112.2 1752487 1753326 R identified by similarity to GP:2231996; match to protein family HMM PF00034; cytochrome c5 complement(1752487..1753326) Neisseria meningitidis MC58 903433 NP_274682.1 CDS tyrB NC_003112.2 1753751 1754944 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1753751..1754944) Neisseria meningitidis MC58 903430 NP_274683.1 CDS trmA NC_003112.2 1754965 1756053 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(1754965..1756053) Neisseria meningitidis MC58 903429 NP_274684.1 CDS aroC NC_003112.2 1756200 1757300 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1756200..1757300 Neisseria meningitidis MC58 903428 NP_274685.1 CDS NMB1681 NC_003112.2 1757392 1757817 D hypothetical protein 1757392..1757817 Neisseria meningitidis MC58 903426 NP_274686.1 CDS parE NC_003112.2 1757891 1759876 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1757891..1759876) Neisseria meningitidis MC58 903425 NP_274687.1 CDS NMB1683 NC_003112.2 1759943 1760467 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(1759943..1760467) Neisseria meningitidis MC58 903424 NP_274688.1 CDS serS NC_003112.2 1760633 1761928 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1760633..1761928 Neisseria meningitidis MC58 903423 NP_274689.1 CDS ldhA NC_003112.2 1762006 1763004 R Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes; D-lactate dehydrogenase complement(1762006..1763004) Neisseria meningitidis MC58 903422 NP_274690.1 CDS prfA NC_003112.2 1763129 1764205 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1763129..1764205) Neisseria meningitidis MC58 903421 NP_274691.1 CDS NMB1687 NC_003112.2 1764310 1765080 R identified by similarity to EGAD:17549; match to protein family HMM PF01026; hypothetical protein complement(1764310..1765080) Neisseria meningitidis MC58 903420 NP_274692.1 CDS ansA NC_003112.2 1765088 1766089 R identified by similarity to EGAD:9104; match to protein family HMM PF00710; L-asparaginase complement(1765088..1766089) Neisseria meningitidis MC58 903419 NP_274693.1 CDS NMB1689 NC_003112.2 1766362 1767045 R identified by similarity to EGAD:28619; match to protein family HMM PF00597; dedA protein complement(1766362..1767045) Neisseria meningitidis MC58 903418 NP_274694.1 CDS glmM NC_003112.2 1767236 1768570 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1767236..1768570) Neisseria meningitidis MC58 903417 NP_274695.1 CDS folP NC_003112.2 1768700 1769557 R identified by similarity to EGAD:13523; match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase complement(1768700..1769557) Neisseria meningitidis MC58 903415 NP_274696.1 CDS NMB1692 NC_003112.2 1769697 1770590 R identified by similarity to EGAD:164552; chorismate mutase-related protein complement(1769697..1770590) Neisseria meningitidis MC58 903413 NP_274697.1 CDS NMB1693 NC_003112.2 1770681 1772795 D hypothetical protein 1770681..1772795 Neisseria meningitidis MC58 903412 NP_274698.1 CDS NMB1694 NC_003112.2 1772859 1774343 R identified by similarity to EGAD:91077; match to protein family HMM PF01977; match to protein family HMM TIGR00148; hypothetical protein complement(1772859..1774343) Neisseria meningitidis MC58 903410 YP_008920721.1 CDS NMB1696a NC_003112.2 1774357 1774872 R hypothetical protein complement(1774357..1774872) Neisseria meningitidis MC58 17925341 YP_008920722.1 CDS NMB1696b NC_003112.2 1774879 1775313 R hypothetical protein complement(1774879..1775313) Neisseria meningitidis MC58 17925343 NP_274700.1 CDS acp-2 NC_003112.2 1775593 1775838 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(1775593..1775838) Neisseria meningitidis MC58 903408 NP_274701.1 CDS NMB1697 NC_003112.2 1775850 1776110 R identified by similarity to EGAD:131410; acyl carrier protein complement(1775850..1776110) Neisseria meningitidis MC58 903406 NP_274702.1 CDS NMB1698 NC_003112.2 1776107 1776865 R identified by similarity to EGAD:90492; match to protein family HMM PF01553; acyltransferase complement(1776107..1776865) Neisseria meningitidis MC58 903405 NP_274703.2 CDS NMB1699 NC_003112.2 1776858 1777613 R hypothetical protein complement(1776858..1777613) Neisseria meningitidis MC58 903404 NP_274705.1 CDS NMB1701 NC_003112.2 1777801 1778301 D hypothetical protein 1777801..1778301 Neisseria meningitidis MC58 903402 NP_274706.1 CDS fabG NC_003112.2 1778329 1779057 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1778329..1779057 Neisseria meningitidis MC58 903401 NP_274707.1 CDS fabF-2 NC_003112.2 1779051 1780301 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1779051..1780301 Neisseria meningitidis MC58 903400 NP_274708.1 CDS lgtF NC_003112.2 1780505 1781263 D identified by similarity to EGAD:124882; match to protein family HMM PF00535; beta-1,4-glucosyltransferase 1780505..1781263 Neisseria meningitidis MC58 903398 NP_274709.1 CDS rfaK NC_003112.2 1781264 1782328 D identified by similarity to EGAD:40699; match to protein family HMM PF00534; alpha 1,2 N-acetylglucosamine transferase 1781264..1782328 Neisseria meningitidis MC58 903397 NP_274710.1 CDS NMB1706 NC_003112.2 1782367 1782537 D hypothetical protein 1782367..1782537 Neisseria meningitidis MC58 903395 NP_274711.1 CDS NMB1707 NC_003112.2 1782715 1784052 D identified by similarity to EGAD:109240; match to protein family HMM PF00209; sodium- and chloride-dependent transporter 1782715..1784052 Neisseria meningitidis MC58 903394 NP_274712.1 CDS thyA NC_003112.2 1784892 1785686 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(1784892..1785686) Neisseria meningitidis MC58 903393 NP_274713.1 CDS gdhA NC_003112.2 1786070 1787404 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1786070..1787404 Neisseria meningitidis MC58 903392 NP_274714.1 CDS NMB1711 NC_003112.2 1787539 1788318 R identified by similarity to EGAD:37331; match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator complement(1787539..1788318) Neisseria meningitidis MC58 903391 NP_274715.1 CDS NMB1712 NC_003112.2 1788749 1789048 D identified by similarity to EGAD:36535; L-lactate permease-like protein 1788749..1789048 Neisseria meningitidis MC58 903390 NP_274716.1 CDS NMB1713 NC_003112.2 1789434 1790399 R identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase complement(1789434..1790399) Neisseria meningitidis MC58 903389 NP_274717.1 CDS mtrE NC_003112.2 1790509 1791912 R identified by similarity to EGAD:17129; match to protein family HMM PF02321; match to protein family HMM TIGR01845; multidrug efflux pump channel protein complement(1790509..1791912) Neisseria meningitidis MC58 903388 NP_274718.1 CDS mtrD NC_003112.2 1791967 1795170 R identified by similarity to EGAD:152391; match to protein family HMM PF00873; match to protein family HMM TIGR00915; multiple transferable resistance system protein MtrD complement(1791967..1795170) Neisseria meningitidis MC58 903387 NP_274719.1 CDS mtrC NC_003112.2 1795182 1796420 R identified by similarity to EGAD:12931; match to protein family HMM PF00529; match to protein family HMM TIGR01730; membrane fusion protein complement(1795182..1796420) Neisseria meningitidis MC58 903386 NP_274720.1 CDS mtrR NC_003112.2 1796823 1797455 D identified by similarity to EGAD:19994; match to protein family HMM PF00440; transcriptional regulator MtrR 1796823..1797455 Neisseria meningitidis MC58 903385 NP_274721.1 CDS NMB1718 NC_003112.2 1797734 1797991 R hypothetical protein complement(1797734..1797991) Neisseria meningitidis MC58 903383 NP_274722.1 CDS mtrF NC_003112.2 1798278 1799846 D identified by similarity to GP:5764655; match to protein family HMM PF03806; match to protein family HMM TIGR00819; efflux pump component MtrF 1798278..1799846 Neisseria meningitidis MC58 903382 NP_274723.1 CDS recC NC_003112.2 1799914 1803123 R identified by similarity to EGAD:8221; match to protein family HMM PF04257; match to protein family HMM TIGR01450; exodeoxyribonuclease V 125 kD polypeptide complement(1799914..1803123) Neisseria meningitidis MC58 903381 NP_274724.1 CDS NMB1721 NC_003112.2 1803225 1804634 R identified by similarity to EGAD:140494; match to protein family HMM PF03929; hypothetical protein complement(1803225..1804634) Neisseria meningitidis MC58 903380 NP_274726.1 CDS fixP NC_003112.2 1805070 1806167 R identified by similarity to EGAD:24821; match to protein family HMM PF00034; match to protein family HMM TIGR00782; cytochrome c oxidase subunit III complement(1805070..1806167) Neisseria meningitidis MC58 903379 YP_008920723.1 CDS NMB1723a NC_003112.2 1806191 1806361 R Cbb3-type cytochrome oxidase subunit 3 complement(1806191..1806361) Neisseria meningitidis MC58 17925342 NP_274727.1 CDS fixO NC_003112.2 1806366 1806977 R CcoO; FixO; cbb3-type cytochrome c oxidase subunit II complement(1806366..1806977) Neisseria meningitidis MC58 903378 NP_274728.1 CDS fixN NC_003112.2 1807004 1808449 R CcoN; FixN; cbb3-type cytochrome c oxidase subunit I complement(1807004..1808449) Neisseria meningitidis MC58 903376 NP_274729.1 CDS NMB1726 NC_003112.2 1808764 1810512 D identified by similarity to EGAD:36443; match to protein family HMM PF05299; hypothetical protein 1808764..1810512 Neisseria meningitidis MC58 903375 NP_274730.1 CDS NMB1727 NC_003112.2 1810577 1811005 D identified by similarity to GP:2564977; match to protein family HMM PF04273; match to protein family HMM TIGR01244; hypothetical protein 1810577..1811005 Neisseria meningitidis MC58 903372 NP_274731.1 CDS exbD NC_003112.2 1811692 1812126 R identified by similarity to EGAD:145337; match to protein family HMM PF02472; biopolymer transport protein complement(1811692..1812126) Neisseria meningitidis MC58 903371 NP_274732.1 CDS exbB NC_003112.2 1812129 1812791 R identified by similarity to EGAD:145333; match to protein family HMM PF01618; biopolymer transport protein complement(1812129..1812791) Neisseria meningitidis MC58 903370 NP_274733.1 CDS tonB NC_003112.2 1812857 1813699 R identified by similarity to EGAD:153359; match to protein family HMM PF03544; match to protein family HMM TIGR01352; TonB protein complement(1812857..1813699) Neisseria meningitidis MC58 903369 NP_274734.1 CDS NMB1731 NC_003112.2 1813954 1814592 D identified by similarity to EGAD:156566; match to protein family HMM PF02163; hypothetical protein 1813954..1814592 Neisseria meningitidis MC58 903368 NP_274735.1 CDS NMB1732 NC_003112.2 1815044 1815844 R identified by similarity to EGAD:135324; transporter complement(1815044..1815844) Neisseria meningitidis MC58 903367 NP_274736.1 CDS NMB1733 NC_003112.2 1815980 1816483 R hypothetical protein complement(1815980..1816483) Neisseria meningitidis MC58 903366 NP_274737.1 CDS grx NC_003112.2 1816820 1817461 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1816820..1817461) Neisseria meningitidis MC58 903365 NP_274738.1 CDS relA NC_003112.2 1817604 1819817 D identified by similarity to GP:2739435; match to protein family HMM PF01842; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; GTP pyrophosphokinase 1817604..1819817 Neisseria meningitidis MC58 903364 YP_008920724.1 CDS NMB1736 NC_003112.2 1820322 1820897 D hypothetical protein 1820322..1820897 Neisseria meningitidis MC58 903363 NP_274739.1 CDS NMB1737 NC_003112.2 1821061 1822464 R identified by similarity to EGAD:40992; match to protein family HMM PF02321; secretion protein complement(1821061..1822464) Neisseria meningitidis MC58 903362 NP_274740.1 CDS NMB1738 NC_003112.2 1822533 1823960 R identified by similarity to GP:558154; match to protein family HMM PF00529; match to protein family HMM TIGR01843; secretion protein complement(1822533..1823960) Neisseria meningitidis MC58 903361 NP_274741.1 CDS NMB1739 NC_003112.2 1824196 1824549 D hypothetical protein 1824196..1824549 Neisseria meningitidis MC58 903360 YP_008920725.1 CDS NMB1741 NC_003112.2 1825462 1826496 D hypothetical protein 1825462..1826496 Neisseria meningitidis MC58 903358 NP_274743.1 CDS NMB1742 NC_003112.2 1826541 1826831 D hypothetical protein 1826541..1826831 Neisseria meningitidis MC58 903356 NP_274744.1 CDS NMB1743 NC_003112.2 1826836 1827033 D hypothetical protein 1826836..1827033 Neisseria meningitidis MC58 903355 NP_274745.1 CDS NMB1744 NC_003112.2 1827041 1827325 D hypothetical protein 1827041..1827325 Neisseria meningitidis MC58 903353 NP_274746.1 CDS NMB1745 NC_003112.2 1827332 1827610 D hypothetical protein 1827332..1827610 Neisseria meningitidis MC58 903352 NP_274748.1 CDS NMB1747 NC_003112.2 1828069 1829574 D identified by similarity to GP:3758871; match to protein family HMM PF05616; tspB protein 1828069..1829574 Neisseria meningitidis MC58 903350 NP_274749.1 CDS NMB1748 NC_003112.2 1829575 1829865 D identified by similarity to EGAD:69712; hypothetical protein 1829575..1829865 Neisseria meningitidis MC58 903349 NP_274750.1 CDS NMB1749 NC_003112.2 1829875 1830960 D identified by similarity to GP:3402502; match to protein family HMM PF05707; hypothetical protein 1829875..1830960 Neisseria meningitidis MC58 903348 NP_274751.1 CDS pivNM-2 NC_003112.2 1831586 1832536 D identified by similarity to EGAD:138632; match to protein family HMM PF01548; match to protein family HMM PF02371; pilin gene inverting protein PivNM-2 1831586..1832536 Neisseria meningitidis MC58 903347 NP_274753.1 CDS NMB1753 NC_003112.2 1834685 1835122 D identified by similarity to EGAD:153654; match to protein family HMM PF04605; VapD-like protein 1834685..1835122 Neisseria meningitidis MC58 903345 NP_274754.1 CDS NMB1754 NC_003112.2 1835119 1835220 R identified by similarity to EGAD:7068; cryptic plasmid protein A-like protein complement(1835119..1835220) Neisseria meningitidis MC58 903344 NP_274756.1 CDS NMB1756 NC_003112.2 1836018 1836212 D hypothetical protein 1836018..1836212 Neisseria meningitidis MC58 903342 NP_274759.1 CDS NMB1759 NC_003112.2 1837441 1838805 D identified by similarity to GP:3329425; match to protein family HMM PF02661; hypothetical protein 1837441..1838805 Neisseria meningitidis MC58 903339 NP_274760.1 CDS NMB1760 NC_003112.2 1839166 1839672 D identified by similarity to EGAD:166833; hypothetical protein 1839166..1839672 Neisseria meningitidis MC58 903338 NP_274761.1 CDS NMB1761 NC_003112.2 1839835 1841088 D identified by similarity to EGAD:97133; match to protein family HMM PF07804; match to protein family HMM PF07805; hypothetical protein 1839835..1841088 Neisseria meningitidis MC58 903337 NP_274762.1 CDS NMB1762 NC_003112.2 1841413 1843200 R identified by similarity to EGAD:149243; match to protein family HMM PF03865; hemolysin activation protein HecB complement(1841413..1843200) Neisseria meningitidis MC58 903336 NP_274763.1 CDS NMB1763 NC_003112.2 1843255 1843713 R identified by similarity to EGAD:41441; match to protein family HMM PF02794; toxin-activating protein complement(1843255..1843713) Neisseria meningitidis MC58 903335 NP_274765.1 CDS NMB1765 NC_003112.2 1844205 1844504 R hypothetical protein complement(1844205..1844504) Neisseria meningitidis MC58 903333 NP_274766.1 CDS NMB1766 NC_003112.2 1844485 1845498 R hypothetical protein complement(1844485..1845498) Neisseria meningitidis MC58 903332 NP_274767.1 CDS NMB1767 NC_003112.2 1845567 1845983 R hypothetical protein complement(1845567..1845983) Neisseria meningitidis MC58 903331 NP_274768.1 CDS NMB1768 NC_003112.2 1845987 1853531 R identified by similarity to EGAD:18919; match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01731; match to protein family HMM TIGR01901; hemagglutinin/hemolysin-like protein complement(1845987..1853531) Neisseria meningitidis MC58 903330 NP_274770.1 CDS NMB1770 NC_003112.2 1854110 1855075 D identified by similarity to EGAD:18338; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase 1854110..1855075 Neisseria meningitidis MC58 903329 NP_274771.1 CDS NMB1771 NC_003112.2 1855143 1855577 R hypothetical protein complement(1855143..1855577) Neisseria meningitidis MC58 903328 NP_274772.1 CDS NMB1772 NC_003112.2 1855574 1857412 R hypothetical protein complement(1855574..1857412) Neisseria meningitidis MC58 903327 NP_274773.1 CDS NMB1773 NC_003112.2 1857447 1857821 R hypothetical protein complement(1857447..1857821) Neisseria meningitidis MC58 903326 NP_274774.1 CDS NMB1774 NC_003112.2 1858099 1858476 R hypothetical protein complement(1858099..1858476) Neisseria meningitidis MC58 903325 NP_274775.1 CDS NMB1775 NC_003112.2 1858485 1860290 R hypothetical protein complement(1858485..1860290) Neisseria meningitidis MC58 903324 NP_274776.1 CDS NMB1776 NC_003112.2 1860287 1860391 R hypothetical protein complement(1860287..1860391) Neisseria meningitidis MC58 903323 NP_274777.2 CDS NMB1777 NC_003112.2 1861157 1861531 R hypothetical protein complement(1861157..1861531) Neisseria meningitidis MC58 903322 NP_274778.1 CDS NMB1778 NC_003112.2 1861423 1861527 R hypothetical protein complement(1861423..1861527) Neisseria meningitidis MC58 903321 NP_274779.1 CDS NMB1779 NC_003112.2 1861550 1867537 R identified by similarity to GP:2623258; match to protein family HMM PF04829; match to protein family HMM PF04830; match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01901; hemagglutinin/hemolysin-like protein complement(1861550..1867537) Neisseria meningitidis MC58 903320 NP_274780.1 CDS NMB1780 NC_003112.2 1867646 1869388 R identified by similarity to EGAD:131262; match to protein family HMM PF03865; hemolysin activation protein HecB complement(1867646..1869388) Neisseria meningitidis MC58 903319 NP_274781.1 CDS NMB1781 NC_003112.2 1869787 1869957 R hypothetical protein complement(1869787..1869957) Neisseria meningitidis MC58 903318 NP_274782.1 CDS NMB1782 NC_003112.2 1869972 1870274 R hypothetical protein complement(1869972..1870274) Neisseria meningitidis MC58 903317 NP_274783.1 CDS NMB1784 NC_003112.2 1871925 1872278 R hypothetical protein complement(1871925..1872278) Neisseria meningitidis MC58 903315 NP_274784.1 CDS NMB1785 NC_003112.2 1872271 1872510 R hypothetical protein complement(1872271..1872510) Neisseria meningitidis MC58 903314 NP_274785.1 CDS NMB1786 NC_003112.2 1872507 1873661 R hypothetical protein complement(1872507..1873661) Neisseria meningitidis MC58 903313 NP_274786.1 CDS argC NC_003112.2 1874194 1875237 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 1874194..1875237 Neisseria meningitidis MC58 903312 NP_274787.1 CDS recG NC_003112.2 1876300 1878342 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1876300..1878342) Neisseria meningitidis MC58 903311 NP_274788.1 CDS secB NC_003112.2 1878428 1878871 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(1878428..1878871) Neisseria meningitidis MC58 903310 NP_274789.1 CDS grxC NC_003112.2 1878892 1879149 R identified by similarity to EGAD:5821; match to protein family HMM PF00462; match to protein family HMM TIGR02181; glutaredoxin 3 complement(1878892..1879149) Neisseria meningitidis MC58 903309 NP_274790.1 CDS cafA NC_003112.2 1879326 1880855 D identified by similarity to EGAD:10184; match to protein family HMM TIGR00757; cytoplasmic axial filament protein 1879326..1880855 Neisseria meningitidis MC58 903308 NP_274791.2 CDS NMB1792 NC_003112.2 1880890 1882140 R identified by similarity to EGAD:28685; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase complement(1880890..1882140) Neisseria meningitidis MC58 903307 NP_274792.1 CDS NMB1794 NC_003112.2 1882534 1883847 R identified by similarity to EGAD:45968; match to protein family HMM PF03600; match to protein family HMM TIGR00784; citrate transporter complement(1882534..1883847) Neisseria meningitidis MC58 903305 NP_274794.1 CDS NMB1796 NC_003112.2 1884417 1884989 R identified by similarity to EGAD:20585; match to protein family HMM PF03358; hypothetical protein complement(1884417..1884989) Neisseria meningitidis MC58 903303 NP_274795.1 CDS NMB1797 NC_003112.2 1885148 1886557 D identified by similarity to GP:3249049; match to protein family HMM PF02113; match to protein family HMM TIGR00666; penicillin-binding protein 3 1885148..1886557 Neisseria meningitidis MC58 903302 NP_274796.1 CDS metK NC_003112.2 1887524 1888693 R methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1887524..1888693) Neisseria meningitidis MC58 903300 NP_274798.1 CDS NMB1801 NC_003112.2 1889039 1889935 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1889039..1889935 Neisseria meningitidis MC58 903297 NP_274799.1 CDS gcp NC_003112.2 1889979 1891043 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(1889979..1891043) Neisseria meningitidis MC58 903296 NP_274800.1 CDS NMB1803 NC_003112.2 1891160 1892347 R identified by similarity to GP:3790606; match to protein family HMM PF01578; cytochrome c-type biogenesis protein complement(1891160..1892347) Neisseria meningitidis MC58 903295 NP_274801.1 CDS NMB1804 NC_003112.2 1892340 1894355 R identified by similarity to GP:3790604; match to protein family HMM PF05140; cytochrome c-type biogenesis protein complement(1892340..1894355) Neisseria meningitidis MC58 903294 NP_274802.1 CDS NMB1805 NC_003112.2 1894569 1895192 R identified by similarity to EGAD:18580; match to protein family HMM PF00034; cytochrome c4 complement(1894569..1895192) Neisseria meningitidis MC58 903293 NP_274803.1 CDS engB NC_003112.2 1895392 1896027 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1895392..1896027 Neisseria meningitidis MC58 903292 NP_274804.1 CDS ponA NC_003112.2 1896148 1898544 R identified by similarity to EGAD:138031; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1 complement(1896148..1898544) Neisseria meningitidis MC58 903291 NP_274805.1 CDS pilM NC_003112.2 1898696 1899811 D identified by similarity to EGAD:151887; match to protein family HMM TIGR01175; pilM protein 1898696..1899811 Neisseria meningitidis MC58 903290 NP_274806.1 CDS pilN NC_003112.2 1899814 1900413 D identified by similarity to EGAD:151888; match to protein family HMM PF05137; pilN protein 1899814..1900413 Neisseria meningitidis MC58 903123 NP_274807.1 CDS pilO NC_003112.2 1900414 1901061 D identified by similarity to GP:1914829; match to protein family HMM PF04350; pilO protein 1900414..1901061 Neisseria meningitidis MC58 903289 NP_274808.1 CDS pilP NC_003112.2 1901079 1901624 D identified by similarity to EGAD:40689; match to protein family HMM PF04351; pilP protein 1901079..1901624 Neisseria meningitidis MC58 903288 NP_274809.1 CDS pilQ NC_003112.2 1901643 1903952 D This PilQ differs from other reported Neisseria PilQ sequences primarily in the length of a repeat region and in the reading frame at the extreme C-terminus, where this sequence follows the consensus of homologs from non-Neisserial species.; identified by similarity to EGAD:40690; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515; pilQ protein 1901643..1903952 Neisseria meningitidis MC58 903122 NP_274810.1 CDS aroK NC_003112.2 1904854 1905366 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1904854..1905366 Neisseria meningitidis MC58 903287 NP_274811.1 CDS aroB NC_003112.2 1905446 1906525 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1905446..1906525 Neisseria meningitidis MC58 903286 NP_274812.1 CDS NMB1815 NC_003112.2 1907492 1908334 D identified by similarity to GP:2661442; match to protein family HMM PF00310; hypothetical protein 1907492..1908334 Neisseria meningitidis MC58 903285 NP_274813.1 CDS nrdR NC_003112.2 1908364 1908828 D identified by similarity to GP:2661443; match to protein family HMM PF03477; transcriptional regulator NrdR 1908364..1908828 Neisseria meningitidis MC58 903284 NP_274814.1 CDS ribD NC_003112.2 1908860 1909969 D identified by similarity to EGAD:27967; match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 1908860..1909969 Neisseria meningitidis MC58 903283 NP_274815.1 CDS NMB1818 NC_003112.2 1910164 1911585 D identified by similarity to EGAD:165571; match to protein family HMM PF01943; lipopolysaccharide biosynthesis protein 1910164..1911585 Neisseria meningitidis MC58 903282 NP_274816.1 CDS NMB1819 NC_003112.2 1911582 1911737 D hypothetical protein 1911582..1911737 Neisseria meningitidis MC58 903281 NP_274817.1 CDS pglB NC_003112.2 1911753 1912994 D identified by similarity to GB:3299889; match to protein family HMM PF00132; match to protein family HMM PF02397; pilin glycosylation protein PglB 1911753..1912994 Neisseria meningitidis MC58 903280 NP_274818.1 CDS pglC NC_003112.2 1913127 1914302 D identified by similarity to GP:3299890; match to protein family HMM PF01041; pilin glycosylation protein 1913127..1914302 Neisseria meningitidis MC58 903279 NP_274819.1 CDS pglD NC_003112.2 1914350 1916260 D identified by similarity to GP:3299891; match to protein family HMM PF02719; match to protein family HMM PF07993; pilin glycosylation protein 1914350..1916260 Neisseria meningitidis MC58 903278 NP_274820.1 CDS avtA NC_003112.2 1916316 1917608 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 1916316..1917608 Neisseria meningitidis MC58 903277 NP_274821.1 CDS NMB1824 NC_003112.2 1917660 1918496 R identified by similarity to EGAD:28400; match to protein family HMM PF02231; hypothetical protein complement(1917660..1918496) Neisseria meningitidis MC58 903276 NP_274822.1 CDS NMB1825 NC_003112.2 1918941 1919144 R hypothetical protein complement(1918941..1919144) Neisseria meningitidis MC58 903275 NP_274823.2 CDS NMB1826 NC_003112.2 1919122 1919355 R identified by similarity to EGAD:13382; match to protein family HMM PF01479; hypothetical protein complement(1919122..1919355) Neisseria meningitidis MC58 903274 NP_274824.1 CDS dnaE NC_003112.2 1919893 1923327 D identified by similarity to EGAD:20624; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594; DNA polymerase III subunit alpha 1919893..1923327 Neisseria meningitidis MC58 903273 NP_274825.1 CDS NMB1828 NC_003112.2 1923761 1924693 R identified by similarity to GP:2738251; match to protein family HMM PF00756; hypothetical protein complement(1923761..1924693) Neisseria meningitidis MC58 903272 NP_274826.1 CDS NMB1829 NC_003112.2 1924763 1926889 R identified by similarity to EGAD:8251; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; TonB-dependent receptor complement(1924763..1926889) Neisseria meningitidis MC58 903271 NP_274827.1 CDS NMB1830 NC_003112.2 1927037 1927696 D identified by similarity to EGAD:13772; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; phosphoglycolate phosphatase 1927037..1927696 Neisseria meningitidis MC58 903270 NP_274828.1 CDS ispH NC_003112.2 1927784 1928752 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(1927784..1928752) Neisseria meningitidis MC58 903269 NP_274829.1 CDS lspA NC_003112.2 1928781 1929308 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(1928781..1929308) Neisseria meningitidis MC58 903268 NP_274830.1 CDS ileS NC_003112.2 1930584 1933373 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1930584..1933373) Neisseria meningitidis MC58 903267 NP_274831.1 CDS ribF NC_003112.2 1933515 1934435 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(1933515..1934435) Neisseria meningitidis MC58 903266 NP_274832.1 CDS tyrS NC_003112.2 1934963 1936258 R identified by similarity to EGAD:13660; match to protein family HMM PF00579; match to protein family HMM TIGR00234; tyrosyl-tRNA synthetase complement(1934963..1936258) Neisseria meningitidis MC58 903265 NP_274833.1 CDS NMB1836 NC_003112.2 1936321 1938192 R identified by similarity to EGAD:153711; match to protein family HMM PF01757; lipopolysaccharide biosynthesis protein WbpC complement(1936321..1938192) Neisseria meningitidis MC58 903263 NP_274834.1 CDS NMB1837 NC_003112.2 1938253 1938507 R hypothetical protein complement(1938253..1938507) Neisseria meningitidis MC58 903262 NP_274835.1 CDS NMB1838 NC_003112.2 1938565 1939656 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1938565..1939656) Neisseria meningitidis MC58 903261 NP_274836.1 CDS fhs NC_003112.2 1939771 1941447 R catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase complement(1939771..1941447) Neisseria meningitidis MC58 903260 NP_274837.1 CDS NMB1840 NC_003112.2 1941622 1942053 D identified by similarity to EGAD:21387; match to protein family HMM PF00892; hypothetical protein 1941622..1942053 Neisseria meningitidis MC58 903259 NP_274838.1 CDS NMB1841 NC_003112.2 1942087 1942782 R identified by similarity to EGAD:48360; match to protein family HMM PF00483; mannose-1-phosphate guanylyltransferase complement(1942087..1942782) Neisseria meningitidis MC58 903258 NP_274839.1 CDS NMB1842 NC_003112.2 1942798 1943298 R identified by similarity to GP:3002549; match to protein family HMM PF01613; match to protein family HMM TIGR02296; 4-hydroxyphenylacetate 3-hydroxylase, small subunit complement(1942798..1943298) Neisseria meningitidis MC58 903257 NP_274840.1 CDS NMB1843 NC_003112.2 1943413 1943853 R identified by similarity to EGAD:43166; match to protein family HMM PF01047; match to protein family HMM TIGR02337; MarR family transcriptional regulator complement(1943413..1943853) Neisseria meningitidis MC58 903256 NP_274841.1 CDS NMB1844 NC_003112.2 1943857 1943979 R hypothetical protein complement(1943857..1943979) Neisseria meningitidis MC58 903255 NP_274842.1 CDS NMB1845 NC_003112.2 1944194 1944703 R identified by similarity to GP:2327006; thioredoxin complement(1944194..1944703) Neisseria meningitidis MC58 903254 NP_274843.1 CDS NMB1846 NC_003112.2 1945073 1946152 D identified by similarity to EGAD:97951; Mrp/NBP35 family protein 1945073..1946152 Neisseria meningitidis MC58 903252 NP_274845.1 CDS carA NC_003112.2 1952630 1953763 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1952630..1953763 Neisseria meningitidis MC58 903249 NP_274847.1 CDS NMB1851 NC_003112.2 1954481 1954741 D hypothetical protein 1954481..1954741 Neisseria meningitidis MC58 903247 NP_274848.1 CDS NMB1852 NC_003112.2 1954738 1955127 D identified by similarity to EGAD:28177; match to protein family HMM PF04480; hypothetical protein 1954738..1955127 Neisseria meningitidis MC58 903246 NP_274849.1 CDS NMB1853 NC_003112.2 1955463 1955735 D hypothetical protein 1955463..1955735 Neisseria meningitidis MC58 903245 NP_274850.1 CDS NMB1854 NC_003112.2 1955809 1956450 D hypothetical protein 1955809..1956450 Neisseria meningitidis MC58 903244 NP_274851.1 CDS carB NC_003112.2 1956479 1959694 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1956479..1959694 Neisseria meningitidis MC58 903243 NP_274852.1 CDS NMB1856 NC_003112.2 1959919 1960818 R identified by similarity to EGAD:15923; match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(1959919..1960818) Neisseria meningitidis MC58 903242 NP_274853.1 CDS mdaB NC_003112.2 1961057 1961635 D identified by similarity to EGAD:90558; match to protein family HMM PF02525; modulator of drug activity B 1961057..1961635 Neisseria meningitidis MC58 903241 NP_274854.1 CDS NMB1858 NC_003112.2 1961632 1962018 R hypothetical protein complement(1961632..1962018) Neisseria meningitidis MC58 903240 NP_274855.1 CDS queA NC_003112.2 1962109 1963149 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(1962109..1963149) Neisseria meningitidis MC58 903239 NP_274856.1 CDS accB NC_003112.2 1963505 1963960 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1963505..1963960 Neisseria meningitidis MC58 903238 NP_274857.1 CDS accC NC_003112.2 1964072 1965433 D identified by similarity to EGAD:27995; match to protein family HMM PF00289; match to protein family HMM PF02785; match to protein family HMM PF02786; match to protein family HMM TIGR00514; acetyl-CoA carboxylase, biotin carboxylase 1964072..1965433 Neisseria meningitidis MC58 904327 NP_274858.1 CDS prmA NC_003112.2 1965694 1966581 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1965694..1966581 Neisseria meningitidis MC58 904326 NP_274859.1 CDS orn NC_003112.2 1966599 1967162 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1966599..1967162 Neisseria meningitidis MC58 904325 NP_274860.1 CDS hemL NC_003112.2 1967566 1968849 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(1967566..1968849) Neisseria meningitidis MC58 904324 NP_274862.1 CDS NMB1866 NC_003112.2 1969634 1970962 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1969634..1970962 Neisseria meningitidis MC58 904322 NP_274863.1 CDS dxs NC_003112.2 1971047 1972960 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(1971047..1972960) Neisseria meningitidis MC58 904321 NP_274864.1 CDS xerC NC_003112.2 1973045 1973950 R identified by similarity to GP:2625019; match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02224; integrase/recombinase XerC complement(1973045..1973950) Neisseria meningitidis MC58 904320 NP_274865.1 CDS cbbA NC_003112.2 1974134 1975198 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 1974134..1975198 Neisseria meningitidis MC58 904319 NP_274866.1 CDS NMB1870 NC_003112.2 1975218 1976180 D hypothetical protein 1975218..1976180 Neisseria meningitidis MC58 904318 NP_274867.1 CDS NMB1871 NC_003112.2 1976327 1977004 D identified by similarity to EGAD:90678; match to protein family HMM PF00814; hypothetical protein 1976327..1977004 Neisseria meningitidis MC58 904317 NP_274868.1 CDS NMB1872 NC_003112.2 1977001 1977441 D identified by similarity to EGAD:8763; match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 1977001..1977441 Neisseria meningitidis MC58 904316 NP_274869.1 CDS NMB1873 NC_003112.2 1977435 1978172 D identified by similarity to EGAD:157119; DNA polymerase 1977435..1978172 Neisseria meningitidis MC58 904315 NP_274870.1 CDS pyrE NC_003112.2 1978234 1978875 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1978234..1978875 Neisseria meningitidis MC58 904314 NP_274871.1 CDS NMB1875 NC_003112.2 1978949 1979383 D hypothetical protein 1978949..1979383 Neisseria meningitidis MC58 904313 NP_274872.1 CDS argA NC_003112.2 1979380 1980690 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 1979380..1980690 Neisseria meningitidis MC58 904312 NP_274873.1 CDS NMB1877 NC_003112.2 1980891 1982906 D identified by similarity to EGAD:132306; match to protein family HMM PF00326; match to protein family HMM PF02897; prolyl oligopeptidase 1980891..1982906 Neisseria meningitidis MC58 904309 NP_274876.1 CDS NMB1880 NC_003112.2 1984213 1985178 D identified by similarity to EGAD:108974; match to protein family HMM PF01497; ABC transporter substrate-binding protein 1984213..1985178 Neisseria meningitidis MC58 904303 NP_274877.1 CDS NMB1881 NC_003112.2 1985735 1986058 D identified by similarity to EGAD:108081; match to protein family HMM PF07883; hypothetical protein 1985735..1986058 Neisseria meningitidis MC58 904300 NP_274878.1 CDS NMB1882 NC_003112.2 1986172 1988349 D identified by similarity to EGAD:8251; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; TonB-dependent receptor 1986172..1988349 Neisseria meningitidis MC58 904299 NP_274879.1 CDS NMB1883 NC_003112.2 1988478 1988768 R hypothetical protein complement(1988478..1988768) Neisseria meningitidis MC58 904298 NP_274880.1 CDS NMB1884 NC_003112.2 1988765 1989088 R identified by similarity to EGAD:156337; match to protein family HMM PF00581; hypothetical protein complement(1988765..1989088) Neisseria meningitidis MC58 904296 NP_274881.1 CDS pcm NC_003112.2 1989168 1989824 R identified by similarity to EGAD:23058; match to protein family HMM PF01135; protein-L-isoaspartate O-methyltransferase complement(1989168..1989824) Neisseria meningitidis MC58 904295 NP_274882.1 CDS NMB1886 NC_003112.2 1989927 1990430 R identified by similarity to EGAD:91612; match to protein family HMM PF01590; hypothetical protein complement(1989927..1990430) Neisseria meningitidis MC58 904292 NP_274883.1 CDS tpiA NC_003112.2 1990609 1991382 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1990609..1991382 Neisseria meningitidis MC58 904291 NP_274884.1 CDS secG NC_003112.2 1991389 1991739 D identified by similarity to EGAD:23175; match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 1991389..1991739 Neisseria meningitidis MC58 904290 NP_274885.1 CDS NMB1889 NC_003112.2 1992527 1992619 D hypothetical protein 1992527..1992619 Neisseria meningitidis MC58 904288 NP_274886.1 CDS NMB1890 NC_003112.2 1992750 1993118 D identified by similarity to EGAD:19883; match to protein family HMM PF06296; hypothetical protein 1992750..1993118 Neisseria meningitidis MC58 904287 NP_274887.1 CDS NMB1891 NC_003112.2 1993115 1993426 D identified by similarity to EGAD:24379; match to protein family HMM PF01381; helix-turn-helix family protein 1993115..1993426 Neisseria meningitidis MC58 904286 NP_274888.1 CDS NMB1892 NC_003112.2 1993536 1993748 D hypothetical protein 1993536..1993748 Neisseria meningitidis MC58 904285 YP_008920726.1 CDS NMB1893 NC_003112.2 1993809 1994690 R hypothetical protein complement(1993809..1994690) Neisseria meningitidis MC58 904283 NP_274889.1 CDS NMB1894 NC_003112.2 1994761 1994892 R identified by similarity to EGAD:108383; leucyl-tRNA synthetase complement(1994761..1994892) Neisseria meningitidis MC58 903121 NP_274890.1 CDS NMB1895 NC_003112.2 1994885 1995028 R identified by similarity to EGAD:28856; DNA adenine methylase, truncation complement(1994885..1995028) Neisseria meningitidis MC58 903119 NP_274891.1 CDS dpnC NC_003112.2 1995012 1995815 R identified by similarity to EGAD:6380; match to protein family HMM PF06044; type II restriction enzyme DpnI complement(1995012..1995815) Neisseria meningitidis MC58 904280 NP_274892.1 CDS leuS NC_003112.2 1995949 1998579 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(1995949..1998579) Neisseria meningitidis MC58 904274 NP_274893.1 CDS mlp NC_003112.2 1998849 1999364 D identified by similarity to EGAD:40759; match to protein family HMM PF04355; lipoprotein 1998849..1999364 Neisseria meningitidis MC58 904273 NP_274894.1 CDS NMB1899 NC_003112.2 1999371 1999814 D hypothetical protein 1999371..1999814 Neisseria meningitidis MC58 904272 NP_274895.1 CDS ppk NC_003112.2 1999890 2002040 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 1999890..2002040 Neisseria meningitidis MC58 904271 NP_274896.1 CDS dnaN NC_003112.2 2003051 2004154 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(2003051..2004154) Neisseria meningitidis MC58 904268 NP_274897.1 CDS dnaA NC_003112.2 2004389 2005945 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(2004389..2005945) Neisseria meningitidis MC58 904267 NP_274898.1 CDS rpmH NC_003112.2 2006237 2006371 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 2006237..2006371 Neisseria meningitidis MC58 904264 NP_274899.1 CDS rnpA NC_003112.2 2006374 2006739 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 2006374..2006739 Neisseria meningitidis MC58 904262 NP_274900.1 CDS NMB1906 NC_003112.2 2006804 2007025 D identified by similarity to EGAD:108432; match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 2006804..2007025 Neisseria meningitidis MC58 904261 NP_274901.1 CDS yidC NC_003112.2 2007197 2008834 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 2007197..2008834 Neisseria meningitidis MC58 904258 NP_274902.1 CDS NMB1908 NC_003112.2 2008915 2009640 R identified by similarity to EGAD:47901; match to protein family HMM PF00590; hypothetical protein complement(2008915..2009640) Neisseria meningitidis MC58 904257 NP_274903.1 CDS maf NC_003112.2 2009687 2010277 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(2009687..2010277) Neisseria meningitidis MC58 904255 NP_274904.1 CDS NMB1910 NC_003112.2 2010425 2010928 D identified by similarity to EGAD:19555; match to protein family HMM PF02620; hypothetical protein 2010425..2010928 Neisseria meningitidis MC58 904254 NP_274905.1 CDS rpmF NC_003112.2 2010962 2011141 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2010962..2011141 Neisseria meningitidis MC58 904253 NP_274906.1 CDS NMB1912 NC_003112.2 2011316 2011843 D identified by similarity to EGAD:133045; match to protein family HMM PF00156; hypothetical protein 2011316..2011843 Neisseria meningitidis MC58 904252 NP_274907.1 CDS plsX NC_003112.2 2011932 2012987 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 2011932..2012987 Neisseria meningitidis MC58 904250 NP_274908.1 CDS NMB1914 NC_003112.2 2013123 2013374 D hypothetical protein 2013123..2013374 Neisseria meningitidis MC58 904249 NP_274909.1 CDS NMB1915 NC_003112.2 2013401 2013790 D hypothetical protein 2013401..2013790 Neisseria meningitidis MC58 904247 NP_274910.1 CDS fabH NC_003112.2 2013972 2014934 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 2013972..2014934 Neisseria meningitidis MC58 904246 NP_274911.1 CDS NMB1917 NC_003112.2 2014981 2015388 D identified by similarity to EGAD:107750; match to protein family HMM PF06961; hypothetical protein 2014981..2015388 Neisseria meningitidis MC58 904245 NP_274912.1 CDS fabD NC_003112.2 2015482 2016408 D identified by similarity to EGAD:22444; match to protein family HMM PF00698; match to protein family HMM TIGR00128; ACP S-malonyltransferase 2015482..2016408 Neisseria meningitidis MC58 904244 NP_274913.1 CDS NMB1919 NC_003112.2 2016546 2018411 D identified by similarity to EGAD:6816; match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR02203; ABC transporter ATP-binding protein 2016546..2018411 Neisseria meningitidis MC58 904243 NP_274914.1 CDS guaA NC_003112.2 2018511 2020076 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2018511..2020076 Neisseria meningitidis MC58 904234 NP_274915.1 CDS fabG NC_003112.2 2020138 2020884 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2020138..2020884 Neisseria meningitidis MC58 904233 NP_274918.1 CDS NMB1924 NC_003112.2 2022019 2022714 R identified by similarity to GP:1658411; match to protein family HMM PF00459; inositol monophosphatase complement(2022019..2022714) Neisseria meningitidis MC58 904231 NP_274919.1 CDS NMB1925 NC_003112.2 2022917 2023642 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2022917..2023642 Neisseria meningitidis MC58 904230 NP_274920.1 CDS lgtE NC_003112.2 2024879 2025721 R identified by similarity to EGAD:40826; match to protein family HMM PF01755; lacto-N-neotetraose biosynthesis glycosyl transferase LgtE complement(2024879..2025721) Neisseria meningitidis MC58 904229 NP_274921.1 CDS NMB1927 NC_003112.2 2025763 2025858 R identified by similarity to EGAD:40776; lacto-N-neotetraose biosynthesis glycosyl transferase-like protein complement(2025763..2025858) Neisseria meningitidis MC58 904228 NP_274922.1 CDS lgtB NC_003112.2 2025870 2026697 R identified by similarity to EGAD:40825; match to protein family HMM PF01755; lacto-N-neotetraose biosynthesis glycosyl transferase LgtB complement(2025870..2026697) Neisseria meningitidis MC58 904227 NP_274923.1 CDS lgtA NC_003112.2 2026739 2027788 R identified by similarity to EGAD:40824; match to protein family HMM PF00535; lacto-N-neotetraose biosynthesis glycosyl transferase complement(2026739..2027788) Neisseria meningitidis MC58 904226 NP_274924.1 CDS glyS NC_003112.2 2027805 2029868 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(2027805..2029868) Neisseria meningitidis MC58 904225 NP_274926.1 CDS glyQ NC_003112.2 2030374 2031279 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(2030374..2031279) Neisseria meningitidis MC58 904222 NP_274927.1 CDS atpC NC_003112.2 2031684 2032106 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(2031684..2032106) Neisseria meningitidis MC58 904221 NP_274928.1 CDS atpD NC_003112.2 2032117 2033514 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(2032117..2033514) Neisseria meningitidis MC58 904218 NP_274929.1 CDS atpG NC_003112.2 2033552 2034427 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(2033552..2034427) Neisseria meningitidis MC58 904217 NP_274930.1 CDS atpA NC_003112.2 2034452 2035999 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(2034452..2035999) Neisseria meningitidis MC58 904216 NP_274931.1 CDS atpH NC_003112.2 2036010 2036543 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(2036010..2036543) Neisseria meningitidis MC58 904215 NP_274932.1 CDS atpF NC_003112.2 2036548 2037018 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(2036548..2037018) Neisseria meningitidis MC58 904214 NP_274933.1 CDS atpE NC_003112.2 2037089 2037325 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(2037089..2037325) Neisseria meningitidis MC58 904213 NP_274934.1 CDS atpB NC_003112.2 2037382 2038248 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(2037382..2038248) Neisseria meningitidis MC58 904211 NP_274935.1 CDS NMB1941 NC_003112.2 2038238 2038591 R hypothetical protein complement(2038238..2038591) Neisseria meningitidis MC58 904210 NP_274938.1 CDS NMB1944 NC_003112.2 2039433 2040293 R identified by similarity to EGAD:137275; match to protein family HMM PF02195; match to protein family HMM TIGR00180; ParB family protein complement(2039433..2040293) Neisseria meningitidis MC58 904207 NP_274939.1 CDS ubiX NC_003112.2 2040448 2041020 D catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; aromatic acid decarboxylase 2040448..2041020 Neisseria meningitidis MC58 904206 NP_274940.1 CDS NMB1946 NC_003112.2 2041082 2041945 R identified by similarity to EGAD:30554; match to protein family HMM PF03180; outer membrane lipoprotein complement(2041082..2041945) Neisseria meningitidis MC58 904205 NP_274941.1 CDS NMB1947 NC_003112.2 2042104 2042790 R identified by similarity to GP:303561; match to protein family HMM PF00528; ABC transporter permease complement(2042104..2042790) Neisseria meningitidis MC58 904203 NP_274942.1 CDS NMB1948 NC_003112.2 2042792 2043529 R identified by similarity to GP:1208966; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(2042792..2043529) Neisseria meningitidis MC58 904202 NP_274943.1 CDS NMB1949 NC_003112.2 2044059 2045909 D identified by similarity to EGAD:23218; match to protein family HMM PF01464; soluble lytic murein transglycosylase 2044059..2045909 Neisseria meningitidis MC58 904201 NP_274944.1 CDS rpsU NC_003112.2 2046198 2046410 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 2046198..2046410 Neisseria meningitidis MC58 904200 NP_274945.1 CDS NMB1951 NC_003112.2 2046446 2046988 D identified by similarity to EGAD:149888; match to protein family HMM PF02637; hypothetical protein 2046446..2046988 Neisseria meningitidis MC58 904199 NP_274946.1 CDS sspB NC_003112.2 2047187 2047579 R identified by similarity to EGAD:140928; match to protein family HMM PF04386; ClpXP protease specificity-enhancing factor complement(2047187..2047579) Neisseria meningitidis MC58 904198 NP_274947.1 CDS sspA NC_003112.2 2047651 2048256 R identified by similarity to EGAD:140927; match to protein family HMM PF00043; match to protein family HMM PF02798; stringent starvation protein A complement(2047651..2048256) Neisseria meningitidis MC58 904197 NP_274948.1 CDS NMB1954 NC_003112.2 2048526 2050187 R hypothetical protein complement(2048526..2050187) Neisseria meningitidis MC58 904196 NP_274949.1 CDS NMB1955 NC_003112.2 2050348 2050974 R identified by similarity to GP:1916729; match to protein family HMM PF03596; match to protein family HMM TIGR00779; cadmium resistance protein complement(2050348..2050974) Neisseria meningitidis MC58 904195 NP_274950.1 CDS rpmE NC_003112.2 2051277 2051492 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(2051277..2051492) Neisseria meningitidis MC58 904194 NP_274952.1 CDS NMB1958 NC_003112.2 2052311 2052811 R identified by similarity to EGAD:109028; thioredoxin complement(2052311..2052811) Neisseria meningitidis MC58 904192 NP_274953.1 CDS NMB1959 NC_003112.2 2052808 2053191 R identified by similarity to EGAD:91226; match to protein family HMM PF03061; match to protein family HMM TIGR00051; hypothetical protein complement(2052808..2053191) Neisseria meningitidis MC58 904191 NP_274954.1 CDS NMB1960 NC_003112.2 2053191 2053673 R hypothetical protein complement(2053191..2053673) Neisseria meningitidis MC58 904190 NP_274955.1 CDS NMB1961 NC_003112.2 2053678 2054505 R identified by similarity to EGAD:90986; match to protein family HMM PF04333; VacJ-like protein complement(2053678..2054505) Neisseria meningitidis MC58 904189 NP_274956.1 CDS NMB1962 NC_003112.2 2054502 2054780 R hypothetical protein complement(2054502..2054780) Neisseria meningitidis MC58 904187 NP_274957.1 CDS NMB1963 NC_003112.2 2054831 2055421 R identified by similarity to EGAD:163193; match to protein family HMM PF05494; hypothetical protein complement(2054831..2055421) Neisseria meningitidis MC58 904186 NP_274958.1 CDS NMB1964 NC_003112.2 2055458 2055952 R identified by similarity to EGAD:28106; match to protein family HMM PF02470; hypothetical protein complement(2055458..2055952) Neisseria meningitidis MC58 904185 NP_274959.1 CDS NMB1965 NC_003112.2 2056003 2056779 R identified by similarity to EGAD:28097; match to protein family HMM PF02405; match to protein family HMM TIGR00056; hypothetical protein complement(2056003..2056779) Neisseria meningitidis MC58 904180 NP_274960.1 CDS NMB1966 NC_003112.2 2056827 2057627 R identified by similarity to EGAD:28098; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(2056827..2057627) Neisseria meningitidis MC58 904178 NP_274961.1 CDS NMB1967 NC_003112.2 2057800 2058717 D identified by similarity to EGAD:49771; match to protein family HMM PF00165; AraC family transcriptional regulator 2057800..2058717 Neisseria meningitidis MC58 904175 NP_274962.1 CDS aldA NC_003112.2 2058977 2060419 D NAD-linked; aldehyde dehydrogenase 2058977..2060419 Neisseria meningitidis MC58 904174 NP_274963.1 CDS NMB1969 NC_003112.2 2061453 2064701 D identified by similarity to EGAD:23198; match to protein family HMM PF00082; match to protein family HMM PF03797; match to protein family HMM TIGR01414; serotype-1-specific antigen 2061453..2064701 Neisseria meningitidis MC58 904173 NP_274964.1 CDS NMB1970 NC_003112.2 2065733 2067514 D identified by similarity to EGAD:90483; match to protein family HMM PF00425; para-aminobenzoate synthetase component I/4-amino-4-deoxychorismate lyase 2065733..2067514 Neisseria meningitidis MC58 904171 NP_274965.1 CDS NMB1971 NC_003112.2 2067573 2069090 R identified by similarity to GP:3523136; match to protein family HMM PF04575; hypothetical protein complement(2067573..2069090) Neisseria meningitidis MC58 904170 NP_274966.1 CDS groEL NC_003112.2 2069786 2071420 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL complement(2069786..2071420) Neisseria meningitidis MC58 904169 NP_274967.1 CDS groES NC_003112.2 2071513 2071803 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(2071513..2071803) Neisseria meningitidis MC58 904167 NP_274968.1 CDS NMB1975 NC_003112.2 2072896 2074431 D identified by similarity to EGAD:29502; match to protein family HMM PF00209; sodium- and chloride-dependent transporter 2072896..2074431 Neisseria meningitidis MC58 904164 NP_274969.1 CDS lysA NC_003112.2 2074556 2075800 R identified by similarity to EGAD:6236; match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase complement(2074556..2075800) Neisseria meningitidis MC58 904163 NP_274970.1 CDS NMB1977 NC_003112.2 2075811 2075981 R hypothetical protein complement(2075811..2075981) Neisseria meningitidis MC58 904162 NP_274971.1 CDS cyaY NC_003112.2 2076052 2076375 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 2076052..2076375 Neisseria meningitidis MC58 904161 NP_274972.1 CDS NMB1979 NC_003112.2 2076402 2077418 D identified by similarity to EGAD:28633; match to protein family HMM PF03601; match to protein family HMM TIGR00698; hypothetical protein 2076402..2077418 Neisseria meningitidis MC58 904160 NP_274973.1 CDS NMB1980 NC_003112.2 2077444 2077863 D identified by similarity to EGAD:29414; hypothetical protein 2077444..2077863 Neisseria meningitidis MC58 904158 NP_274974.1 CDS NMB1981 NC_003112.2 2077885 2078391 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2077885..2078391 Neisseria meningitidis MC58 904156 NP_274975.1 CDS polA NC_003112.2 2078537 2081353 D identified by similarity to EGAD:23009; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF01612; match to protein family HMM PF02739; match to protein family HMM TIGR00593; DNA polymerase I 2078537..2081353 Neisseria meningitidis MC58 904155 NP_274976.1 CDS NMB1983 NC_003112.2 2082699 2083370 D hypothetical protein 2082699..2083370 Neisseria meningitidis MC58 904154 NP_274977.1 CDS hap NC_003112.2 2084859 2089232 R identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; adhesion and penetration protein complement(2084859..2089232) Neisseria meningitidis MC58 904147 NP_274978.1 CDS NMB1986 NC_003112.2 2089366 2089797 R hypothetical protein complement(2089366..2089797) Neisseria meningitidis MC58 904146 NP_274979.1 CDS trmE NC_003112.2 2090082 2091428 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2090082..2091428 Neisseria meningitidis MC58 904145 NP_274980.1 CDS frpB NC_003112.2 2092652 2094796 D identified by similarity to EGAD:133971; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; iron-regulated outer membrane protein FrpB 2092652..2094796 Neisseria meningitidis MC58 904143 NP_274981.1 CDS NMB1989 NC_003112.2 2095513 2096478 D identified by similarity to EGAD:108974; match to protein family HMM PF01497; iron ABC transporter substrate-binding protein 2095513..2096478 Neisseria meningitidis MC58 904142 NP_274982.1 CDS NMB1990 NC_003112.2 2096642 2097610 D identified by similarity to EGAD:108968; match to protein family HMM PF01032; iron ABC transporter permease 2096642..2097610 Neisseria meningitidis MC58 904141 NP_274983.1 CDS NMB1991 NC_003112.2 2097600 2098574 D identified by similarity to EGAD:108970; match to protein family HMM PF01032; iron(III) ABC transporter permease 2097600..2098574 Neisseria meningitidis MC58 904139 NP_274984.1 CDS NMB1992 NC_003112.2 2098618 2099244 D hypothetical protein 2098618..2099244 Neisseria meningitidis MC58 904137 NP_274985.1 CDS NMB1993 NC_003112.2 2099327 2100085 D identified by similarity to EGAD:108972; match to protein family HMM PF00005; iron(III) ABC transporter ATP-binding protein 2099327..2100085 Neisseria meningitidis MC58 904135 NP_274986.1 CDS NMB1994 NC_003112.2 2100383 2101477 D identified by similarity to GP:2735093; match to protein family HMM PF03895; adhesin/invasin 2100383..2101477 Neisseria meningitidis MC58 904134 NP_274987.1 CDS glnB NC_003112.2 2101543 2101881 R identified by similarity to EGAD:7369; match to protein family HMM PF00543; nitrogen regulatory protein P-II 1 complement(2101543..2101881) Neisseria meningitidis MC58 904133 NP_274988.1 CDS purL NC_003112.2 2102032 2105994 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2102032..2105994 Neisseria meningitidis MC58 904131 NP_274989.1 CDS gloB NC_003112.2 2106089 2106847 D identified by similarity to EGAD:35929; match to protein family HMM PF00753; hydroxyacylglutathione hydrolase 2106089..2106847 Neisseria meningitidis MC58 904130 NP_274990.1 CDS NMB1998 NC_003112.2 2107161 2111456 D identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; serine-type peptidase 2107161..2111456 Neisseria meningitidis MC58 904129 NP_274991.1 CDS mgtE NC_003112.2 2111688 2113142 D identified by similarity to EGAD:107500; match to protein family HMM PF00571; match to protein family HMM PF01769; match to protein family HMM PF03448; match to protein family HMM TIGR00400; magnesium transporter 2111688..2113142 Neisseria meningitidis MC58 904127 NP_274992.1 CDS hslO NC_003112.2 2113228 2114136 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin complement(2113228..2114136) Neisseria meningitidis MC58 904125 NP_274993.1 CDS NMB2001 NC_003112.2 2114381 2115136 D identified by similarity to EGAD:91561; match to protein family HMM PF00877; hypothetical protein 2114381..2115136 Neisseria meningitidis MC58 904124 NP_274994.1 CDS NMB2002 NC_003112.2 2115155 2115373 D hypothetical protein 2115155..2115373 Neisseria meningitidis MC58 904123 NP_274995.1 CDS NMB2003 NC_003112.2 2115518 2115865 D identified by similarity to EGAD:9831; match to protein family HMM PF03788; hypothetical protein 2115518..2115865 Neisseria meningitidis MC58 904119 NP_274996.1 CDS NMB2004 NC_003112.2 2115862 2116554 D identified by similarity to EGAD:8297; match to protein family HMM PF04172; hypothetical protein 2115862..2116554 Neisseria meningitidis MC58 904117 NP_274997.1 CDS argJ NC_003112.2 2116621 2117841 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 2116621..2117841 Neisseria meningitidis MC58 904115 NP_274998.1 CDS NMB2006 NC_003112.2 2117901 2119310 D identified by similarity to EGAD:47927; match to protein family HMM PF00654; chloride channel protein-related protein 2117901..2119310 Neisseria meningitidis MC58 904114 NP_274999.1 CDS NMB2007 NC_003112.2 2119500 2120891 D identified by similarity to GP:1742299; ATP-dependent DNA helicase 2119500..2120891 Neisseria meningitidis MC58 903117 NP_275000.1 CDS NMB2008 NC_003112.2 2121035 2122678 D identified by similarity to EGAD:42946; ABC transporter ATP-binding protein-like protein 2121035..2122678 Neisseria meningitidis MC58 904113 NP_275002.1 CDS NMB2010 NC_003112.2 2123116 2124693 D identified by similarity to EGAD:8243; match to protein family HMM PF00884; hypothetical protein 2123116..2124693 Neisseria meningitidis MC58 904111 NP_275003.1 CDS NMB2011 NC_003112.2 2124759 2128178 D identified by similarity to GP:1742310; ATP-dependent RNA helicase HrpA, truncation 2124759..2128178 Neisseria meningitidis MC58 903114 NP_275004.1 CDS NMB2012 NC_003112.2 2128211 2129302 R identified by similarity to EGAD:161488; match to protein family HMM PF06114; match to protein family HMM TIGR01199; transcriptional regulator complement(2128211..2129302) Neisseria meningitidis MC58 904110 NP_275005.1 CDS NMB2013 NC_003112.2 2129318 2129962 R hypothetical protein complement(2129318..2129962) Neisseria meningitidis MC58 904109 NP_275007.1 CDS NMB2015 NC_003112.2 2130656 2130925 D hypothetical protein 2130656..2130925 Neisseria meningitidis MC58 904107 NP_275008.1 CDS NMB2016 NC_003112.2 2131086 2131535 R identified by similarity to GP:2073462; match to protein family HMM PF07963; match to protein family HMM TIGR02532; type IV pilin-like protein complement(2131086..2131535) Neisseria meningitidis MC58 904106 NP_275009.1 CDS NMB2017 NC_003112.2 2131623 2132069 R identified by similarity to EGAD:18958; match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259; ComEA-like protein complement(2131623..2132069) Neisseria meningitidis MC58 904104 NP_275010.1 CDS NMB2018 NC_003112.2 2137791 2138453 R identified by similarity to EGAD:27877; match to protein family HMM PF00849; match to protein family HMM TIGR01621; hypothetical protein complement(2137791..2138453) Neisseria meningitidis MC58 904093 NP_275011.1 CDS coaD NC_003112.2 2138479 2138991 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(2138479..2138991) Neisseria meningitidis MC58 904092 NP_275012.1 CDS NMB2020 NC_003112.2 2139115 2139798 R identified by similarity to EGAD:6204; match to protein family HMM PF01027; hypothetical protein complement(2139115..2139798) Neisseria meningitidis MC58 904090 NP_275013.1 CDS NMB2021 NC_003112.2 2139955 2140221 R identified by similarity to EGAD:27927; match to protein family HMM PF04362; hypothetical protein complement(2139955..2140221) Neisseria meningitidis MC58 904089 NP_275014.1 CDS NMB2022 NC_003112.2 2140294 2140764 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2140294..2140764) Neisseria meningitidis MC58 904088 NP_275015.1 CDS NMB2023 NC_003112.2 2140818 2141204 R identified by similarity to EGAD:27850; match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein complement(2140818..2141204) Neisseria meningitidis MC58 904084 NP_275016.1 CDS NMB2024 NC_003112.2 2141263 2141868 R identified by similarity to EGAD:45797; match to protein family HMM PF01467; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; hypothetical protein complement(2141263..2141868) Neisseria meningitidis MC58 904082 NP_275017.1 CDS NMB2025 NC_003112.2 2141865 2142464 R identified by similarity to EGAD:108434; match to protein family HMM PF00484; hypothetical protein complement(2141865..2142464) Neisseria meningitidis MC58 904081 NP_275018.1 CDS NMB2026 NC_003112.2 2142493 2144088 R identified by similarity to GP:3319739; match to protein family HMM PF00528; ABC transporter permease complement(2142493..2144088) Neisseria meningitidis MC58 904080 NP_275019.1 CDS gntP NC_003112.2 2144427 2145812 D identified by similarity to EGAD:36585; match to protein family HMM PF02447; match to protein family HMM TIGR00791; gluconate permease 2144427..2145812 Neisseria meningitidis MC58 904076 NP_275020.1 CDS gntK NC_003112.2 2145832 2146350 D identified by similarity to EGAD:30331; match to protein family HMM TIGR01313; thermoresistant gluconokinase 2145832..2146350 Neisseria meningitidis MC58 904075 NP_275021.1 CDS thrB NC_003112.2 2146689 2147606 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase complement(2146689..2147606) Neisseria meningitidis MC58 903113 NP_275022.1 CDS ubiG NC_003112.2 2147643 2148371 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(2147643..2148371) Neisseria meningitidis MC58 904071 NP_275023.1 CDS mtr NC_003112.2 2148523 2149764 D identified by similarity to EGAD:28929; match to protein family HMM PF03222; match to protein family HMM TIGR00837; amino-acid transport protein 2148523..2149764 Neisseria meningitidis MC58 904070 NP_275024.1 CDS NMB2033 NC_003112.2 2151215 2151778 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 2151215..2151778 Neisseria meningitidis MC58 904065 NP_275025.1 CDS NMB2034 NC_003112.2 2151807 2152550 D identified by similarity to EGAD:162666; match to protein family HMM PF01553; 1-acyl-SN-glycerol-3-phosphate acyltransferase 2151807..2152550 Neisseria meningitidis MC58 904064 NP_275026.1 CDS NMB2035 NC_003112.2 2152547 2153239 D identified by similarity to EGAD:105006; match to protein family HMM PF01863; hypothetical protein 2152547..2153239 Neisseria meningitidis MC58 904063 NP_275027.1 CDS truA NC_003112.2 2154537 2155334 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2154537..2155334 Neisseria meningitidis MC58 904060 NP_275028.1 CDS NMB2037 NC_003112.2 2155457 2155696 D hypothetical protein 2155457..2155696 Neisseria meningitidis MC58 904059 NP_275029.1 CDS NMB2038 NC_003112.2 2155684 2156007 D identified by similarity to EGAD:108126; match to protein family HMM PF02452; PemK-like protein 2155684..2156007 Neisseria meningitidis MC58 904055 NP_275030.1 CDS porB NC_003112.2 2157529 2158524 D identified by similarity to EGAD:7492; match to protein family HMM PF00267; major outer membrane protein PIB 2157529..2158524 Neisseria meningitidis MC58 904054 NP_275031.1 CDS thiC NC_003112.2 2159620 2161521 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(2159620..2161521) Neisseria meningitidis MC58 904053 NP_275032.1 CDS NMB2041 NC_003112.2 2162135 2163010 D identified by similarity to EGAD:53884; match to protein family HMM PF00293; thiamin pyrophosphokinase-like protein 2162135..2163010 Neisseria meningitidis MC58 904050 NP_275033.1 CDS potA-2 NC_003112.2 2163019 2163957 D identified by similarity to EGAD:28341; match to protein family HMM PF00005; ABC transporter ATP-binding protein 2163019..2163957 Neisseria meningitidis MC58 904049 NP_275034.1 CDS ptsI NC_003112.2 2166545 2168320 R identified by similarity to EGAD:19051; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase complement(2166545..2168320) Neisseria meningitidis MC58 904047 NP_275035.1 CDS ptsH NC_003112.2 2168320 2168589 R identified by similarity to EGAD:17827; match to protein family HMM PF00381; match to protein family HMM TIGR01003; sugar transport PTS system phosphocarrier protein HPr complement(2168320..2168589) Neisseria meningitidis MC58 904045 NP_275036.1 CDS NMB2046 NC_003112.2 2168658 2169116 R identified by similarity to EGAD:24904; match to protein family HMM PF03610; PTS system, IIAB component complement(2168658..2169116) Neisseria meningitidis MC58 904044 NP_275037.1 CDS NMB2047 NC_003112.2 2169176 2169739 R Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase complement(2169176..2169739) Neisseria meningitidis MC58 904042 NP_275038.1 CDS ligA-2 NC_003112.2 2169808 2170632 R catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase complement(2169808..2170632) Neisseria meningitidis MC58 904041 NP_275039.1 CDS NMB2049 NC_003112.2 2170724 2171356 D identified by similarity to EGAD:91564; match to protein family HMM PF00753; glyoxalase II family protein 2170724..2171356 Neisseria meningitidis MC58 904038 NP_275040.1 CDS NMB2050 NC_003112.2 2171563 2173347 R identified by similarity to EGAD:23818; match to protein family HMM PF02646; hypothetical protein complement(2171563..2173347) Neisseria meningitidis MC58 904037 NP_275041.1 CDS petC NC_003112.2 2173686 2174486 R identified by similarity to EGAD:10603; match to protein family HMM PF02167; cytochrome C1 precursor complement(2173686..2174486) Neisseria meningitidis MC58 904035 NP_275042.1 CDS petB NC_003112.2 2174486 2175835 R identified by similarity to EGAD:10936; match to protein family HMM PF00032; match to protein family HMM PF00033; cytochrome B complement(2174486..2175835) Neisseria meningitidis MC58 904030 NP_275043.1 CDS petA NC_003112.2 2175854 2176435 R identified by similarity to EGAD:24965; match to protein family HMM PF00355; match to protein family HMM TIGR01409; match to protein family HMM TIGR01416; ubiquinol-cytochrome c reductase iron-sulfur subunit complement(2175854..2176435) Neisseria meningitidis MC58 904028 NP_275044.1 CDS NMB2054 NC_003112.2 2176558 2177307 R identified by similarity to EGAD:109841; match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein complement(2176558..2177307) Neisseria meningitidis MC58 904027 NP_275045.1 CDS NMB2055 NC_003112.2 2177438 2178367 D identified by similarity to EGAD:28725; match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2177438..2178367 Neisseria meningitidis MC58 904026 NP_275046.1 CDS rpsI NC_003112.2 2178622 2179014 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(2178622..2179014) Neisseria meningitidis MC58 904024 NP_275047.1 CDS rplM NC_003112.2 2179024 2179455 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(2179024..2179455) Neisseria meningitidis MC58 904023 NP_275048.1 CDS NMB2058 NC_003112.2 2179818 2180123 R identified by similarity to EGAD:29842; match to protein family HMM PF05164; hypothetical protein complement(2179818..2180123) Neisseria meningitidis MC58 904022 NP_275049.1 CDS NMB2059 NC_003112.2 2180134 2180463 R hypothetical protein complement(2180134..2180463) Neisseria meningitidis MC58 904021 NP_275050.1 CDS gpsA NC_003112.2 2180518 2181507 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(2180518..2181507) Neisseria meningitidis MC58 904020 NP_275051.1 CDS ppc NC_003112.2 2181630 2184332 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(2181630..2184332) Neisseria meningitidis MC58 904019 NP_275052.1 CDS thiF NC_003112.2 2184502 2185272 D identified by similarity to EGAD:12848; match to protein family HMM PF00899; match to protein family HMM PF05237; thiF protein 2184502..2185272 Neisseria meningitidis MC58 904016 NP_275053.1 CDS NMB2063 NC_003112.2 2185836 2186060 R identified by similarity to EGAD:19441; match to protein family HMM PF04102; hypothetical protein complement(2185836..2186060) Neisseria meningitidis MC58 904015 NP_275054.1 CDS NMB2064 NC_003112.2 2186061 2187449 R identified by similarity to EGAD:28966; match to protein family HMM PF03553; hypothetical protein complement(2186061..2187449) Neisseria meningitidis MC58 904014 NP_275055.1 CDS hemK NC_003112.2 2187535 2188806 R identified by similarity to EGAD:37566; match to protein family HMM TIGR00536; hemK protein complement(2187535..2188806) Neisseria meningitidis MC58 904010 NP_275056.1 CDS tldD NC_003112.2 2188871 2190313 R identified by similarity to EGAD:30245; match to protein family HMM PF01523; tldD protein complement(2188871..2190313) Neisseria meningitidis MC58 904006 NP_275057.1 CDS cytX NC_003112.2 2190703 2191926 D identified by similarity to EGAD:158421; match to protein family HMM PF02133; match to protein family HMM TIGR02358; hydroxymethylpyrimidine transporter CytX 2190703..2191926 Neisseria meningitidis MC58 904005 NP_275058.1 CDS thiO NC_003112.2 2191923 2193023 D identified by similarity to GP:2627327; match to protein family HMM PF01266; glycine oxidase ThiO 2191923..2193023 Neisseria meningitidis MC58 904004 NP_275059.1 CDS thiE NC_003112.2 2193045 2193662 D identified by similarity to EGAD:10927; match to protein family HMM PF02581; match to protein family HMM TIGR00693; thiamin-phosphate pyrophosphorylase 2193045..2193662 Neisseria meningitidis MC58 904001 NP_275060.1 CDS thiS NC_003112.2 2194084 2194278 D identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683; thiamine biosynthesis protein ThiS 2194084..2194278 Neisseria meningitidis MC58 903999 NP_275061.1 CDS thiG NC_003112.2 2194492 2195280 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 2194492..2195280 Neisseria meningitidis MC58 903997 NP_275062.1 CDS NMB2072 NC_003112.2 2195394 2195537 D hypothetical protein 2195394..2195537 Neisseria meningitidis MC58 903995 NP_275064.1 CDS NMB2074 NC_003112.2 2196043 2196909 R hypothetical protein complement(2196043..2196909) Neisseria meningitidis MC58 903992 NP_275065.1 CDS NMB2075 NC_003112.2 2196921 2198699 R activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins and catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; bifunctional biotin--[acetyl-CoA-carboxylase] ligase/pantothenate kinase complement(2196921..2198699) Neisseria meningitidis MC58 903989 NP_275066.1 CDS aut NC_003112.2 2198696 2199202 R identified by similarity to EGAD:41926; match to protein family HMM PF01467; match to protein family HMM TIGR00125; match to protein family HMM TIGR02199; aut protein complement(2198696..2199202) Neisseria meningitidis MC58 903988 NP_275067.1 CDS NMB2078 NC_003112.2 2200757 2201338 R identified by similarity to EGAD:28554; match to protein family HMM PF06271; hypothetical protein complement(2200757..2201338) Neisseria meningitidis MC58 903978 NP_275068.1 CDS asd NC_003112.2 2201514 2202629 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 2201514..2202629 Neisseria meningitidis MC58 903977 NP_275069.1 CDS NMB2080 NC_003112.2 2202857 2203387 R hypothetical protein complement(2202857..2203387) Neisseria meningitidis MC58 903975 NP_275070.1 CDS NMB2081 NC_003112.2 2203398 2203742 R hypothetical protein complement(2203398..2203742) Neisseria meningitidis MC58 903974 NP_275071.1 CDS exoA NC_003112.2 2203729 2204508 R identified by similarity to EGAD:19899; match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease complement(2203729..2204508) Neisseria meningitidis MC58 903973 NP_275072.1 CDS cysS NC_003112.2 2204591 2206012 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(2204591..2206012) Neisseria meningitidis MC58 903970 NP_275073.1 CDS NMB2085 NC_003112.2 2206700 2207749 R hypothetical protein complement(2206700..2207749) Neisseria meningitidis MC58 903967 NP_275074.1 CDS obgE NC_003112.2 2207832 2208986 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(2207832..2208986) Neisseria meningitidis MC58 903966 NP_275075.1 CDS NMB2087 NC_003112.2 2209472 2209834 R hypothetical protein complement(2209472..2209834) Neisseria meningitidis MC58 903964 NP_275076.1 CDS NMB2088 NC_003112.2 2209933 2210808 R identified by similarity to EGAD:28643; match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein complement(2209933..2210808) Neisseria meningitidis MC58 903963 NP_275077.1 CDS NMB2089 NC_003112.2 2210854 2211201 D identified by similarity to EGAD:89286; match to protein family HMM PF02021; match to protein family HMM TIGR00252; hypothetical protein 2210854..2211201 Neisseria meningitidis MC58 903961 NP_275078.1 CDS gmhA NC_003112.2 2211206 2211799 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 2211206..2211799 Neisseria meningitidis MC58 903960 NP_275079.1 CDS NMB2091 NC_003112.2 2211863 2212471 D identified by similarity to EGAD:28637; match to protein family HMM PF04972; hemolysin 2211863..2212471 Neisseria meningitidis MC58 903958 NP_275080.1 CDS NMB2092 NC_003112.2 2212479 2213111 D hypothetical protein 2212479..2213111 Neisseria meningitidis MC58 903956 NP_275081.1 CDS map NC_003112.2 2213151 2213930 D identified by similarity to EGAD:13057; match to protein family HMM PF00557; match to protein family HMM TIGR00500; methionine aminopeptidase 2213151..2213930 Neisseria meningitidis MC58 903955 NP_275082.1 CDS NMB2094 NC_003112.2 2214085 2214384 D hypothetical protein 2214085..2214384 Neisseria meningitidis MC58 903952 NP_275083.1 CDS NMB2095 NC_003112.2 2214622 2214996 D identified by similarity to EGAD:126793; adhesin complex protein 2214622..2214996 Neisseria meningitidis MC58 903950 NP_275084.1 CDS yojH NC_003112.2 2215184 2216650 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2215184..2216650) Neisseria meningitidis MC58 903948 NP_275085.1 CDS NMB2097 NC_003112.2 2216702 2216791 R hypothetical protein complement(2216702..2216791) Neisseria meningitidis MC58 903947 NP_275086.1 CDS NMB2098 NC_003112.2 2217187 2217777 R identified by similarity to GP:2897873; hypothetical protein complement(2217187..2217777) Neisseria meningitidis MC58 903946 NP_275087.1 CDS NMB2099 NC_003112.2 2217838 2218419 R identified by similarity to EGAD:33024; match to protein family HMM PF01812; hypothetical protein complement(2217838..2218419) Neisseria meningitidis MC58 903943 NP_275088.1 CDS NMB2100 NC_003112.2 2218497 2218730 D hypothetical protein 2218497..2218730 Neisseria meningitidis MC58 903941 NP_275089.1 CDS rpsB NC_003112.2 2218903 2219631 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2218903..2219631 Neisseria meningitidis MC58 903940 NP_275090.1 CDS tsf NC_003112.2 2219760 2220614 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2219760..2220614 Neisseria meningitidis MC58 903937 NP_275091.1 CDS pyrH NC_003112.2 2220831 2221550 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 2220831..2221550 Neisseria meningitidis MC58 903933 NP_275092.1 CDS mafB NC_003112.2 2222737 2224188 D identified by similarity to GP:4838555; match to protein family HMM PF06255; mafB protein 2222737..2224188 Neisseria meningitidis MC58 903930 NP_275093.1 CDS NMB2106 NC_003112.2 2224185 2224541 D hypothetical protein 2224185..2224541 Neisseria meningitidis MC58 903929 NP_275097.1 CDS NMB2110 NC_003112.2 2225929 2226300 D hypothetical protein 2225929..2226300 Neisseria meningitidis MC58 903922 NP_275099.1 CDS NMB2112 NC_003112.2 2227348 2227617 D hypothetical protein 2227348..2227617 Neisseria meningitidis MC58 903919 NP_275100.1 CDS NMB2113 NC_003112.2 2227640 2227942 D hypothetical protein 2227640..2227942 Neisseria meningitidis MC58 903519 NP_275102.1 CDS NMB2115 NC_003112.2 2228631 2228975 D hypothetical protein 2228631..2228975 Neisseria meningitidis MC58 903512 NP_275103.1 CDS NMB2116 NC_003112.2 2229013 2229357 D hypothetical protein 2229013..2229357 Neisseria meningitidis MC58 903511 NP_275104.1 CDS NMB2118 NC_003112.2 2230382 2230699 D hypothetical protein 2230382..2230699 Neisseria meningitidis MC58 903488 NP_275106.1 CDS NMB2120 NC_003112.2 2231513 2231914 D hypothetical protein 2231513..2231914 Neisseria meningitidis MC58 903473 NP_275107.1 CDS NMB2121 NC_003112.2 2232073 2232417 D hypothetical protein 2232073..2232417 Neisseria meningitidis MC58 903454 NP_275108.1 CDS NMB2122 NC_003112.2 2232451 2232555 D identified by similarity to GP:4838555; MafB-like protein 2232451..2232555 Neisseria meningitidis MC58 903449 NP_275109.1 CDS NMB2123 NC_003112.2 2232560 2232916 D hypothetical protein 2232560..2232916 Neisseria meningitidis MC58 903432 NP_275110.1 CDS NMB2124 NC_003112.2 2232964 2233092 D hypothetical protein 2232964..2233092 Neisseria meningitidis MC58 903427 NP_275111.1 CDS NMB2125 NC_003112.2 2233089 2233463 D hypothetical protein 2233089..2233463 Neisseria meningitidis MC58 903416 NP_275112.1 CDS NMB2127 NC_003112.2 2234420 2235406 R identified by similarity to EGAD:106898; match to protein family HMM PF01343; protease complement(2234420..2235406) Neisseria meningitidis MC58 903411 NP_275113.1 CDS NMB2128 NC_003112.2 2235446 2236246 R identified by similarity to EGAD:103771; CinA-like protein complement(2235446..2236246) Neisseria meningitidis MC58 903407 NP_275114.1 CDS argG NC_003112.2 2236559 2237902 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 2236559..2237902 Neisseria meningitidis MC58 903396 NP_275115.1 CDS NMB2130 NC_003112.2 2237950 2238192 D hypothetical protein 2237950..2238192 Neisseria meningitidis MC58 903377 NP_275116.1 CDS NMB2131 NC_003112.2 2238185 2238400 D hypothetical protein 2238185..2238400 Neisseria meningitidis MC58 903373 NP_275117.1 CDS NMB2132 NC_003112.2 2238476 2239942 R identified by similarity to EGAD:39989; match to protein family HMM PF01298; transferrin-binding protein-like protein complement(2238476..2239942) Neisseria meningitidis MC58 903357 NP_275118.1 CDS NMB2133 NC_003112.2 2240197 2241426 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(2240197..2241426) Neisseria meningitidis MC58 903354 NP_275119.1 CDS NMB2134 NC_003112.2 2241899 2243806 D identified by similarity to EGAD:24660; match to protein family HMM PF01103; hypothetical protein 2241899..2243806 Neisseria meningitidis MC58 903298 NP_275120.1 CDS NMB2135 NC_003112.2 2243813 2248030 D identified by similarity to EGAD:29466; match to protein family HMM PF04357; hypothetical protein 2243813..2248030 Neisseria meningitidis MC58 903264 NP_275121.1 CDS NMB2136 NC_003112.2 2249513 2250970 D identified by similarity to EGAD:108941; match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; peptide transporter 2249513..2250970 Neisseria meningitidis MC58 903237 NP_275123.1 CDS prfB NC_003112.2 2251863 2252966 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(2251863..2252966) Neisseria meningitidis MC58 903234 NP_275124.1 CDS NMB2139 NC_003112.2 2253069 2253962 R identified by similarity to EGAD:108195; match to protein family HMM PF01734; hypothetical protein complement(2253069..2253962) Neisseria meningitidis MC58 903233 NP_275125.1 CDS NMB2140 NC_003112.2 2254307 2254756 D identified by similarity to EGAD:28593; match to protein family HMM PF07681; hypothetical protein 2254307..2254756 Neisseria meningitidis MC58 903232 NP_275126.1 CDS NMB2141 NC_003112.2 2254829 2255137 D hypothetical protein 2254829..2255137 Neisseria meningitidis MC58 903231 NP_275127.1 CDS NMB2142 NC_003112.2 2255229 2256095 D identified by similarity to EGAD:28591; match to protein family HMM PF05114; hypothetical protein 2255229..2256095 Neisseria meningitidis MC58 903230 NP_275128.1 CDS NMB2143 NC_003112.2 2256085 2256831 D identified by similarity to EGAD:28581; hypothetical protein 2256085..2256831 Neisseria meningitidis MC58 903229 NP_275129.1 CDS NMB2144 NC_003112.2 2256853 2257440 D Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 2256853..2257440 Neisseria meningitidis MC58 903228 NP_275130.1 CDS NMB2145 NC_003112.2 2257446 2257625 D hypothetical protein 2257446..2257625 Neisseria meningitidis MC58 903227 NP_275131.1 CDS NMB2146 NC_003112.2 2257745 2257855 D hypothetical protein 2257745..2257855 Neisseria meningitidis MC58 903226 NP_275132.1 CDS NMB2147 NC_003112.2 2257884 2258306 D hypothetical protein 2257884..2258306 Neisseria meningitidis MC58 903225 NP_275133.1 CDS NMB2148 NC_003112.2 2258780 2259745 D identified by similarity to EGAD:9780; match to protein family HMM PF00665; match to protein family HMM TIGR01199; IS30 family transposase 2258780..2259745 Neisseria meningitidis MC58 903224 NP_275134.1 CDS NMB2149 NC_003112.2 2259834 2260094 R hypothetical protein complement(2259834..2260094) Neisseria meningitidis MC58 903223 NP_275135.1 CDS NMB2150 NC_003112.2 2260479 2261048 R identified by similarity to GP:606216; match to protein family HMM PF01300; hypothetical protein complement(2260479..2261048) Neisseria meningitidis MC58 903222 NP_275136.1 CDS purD NC_003112.2 2261115 2262386 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(2261115..2262386) Neisseria meningitidis MC58 903221 NP_275137.1 CDS NMB2152 NC_003112.2 2262544 2262861 D hypothetical protein 2262544..2262861 Neisseria meningitidis MC58 903220 NP_275138.1 CDS NMB2153 NC_003112.2 2262913 2263524 R identified by similarity to EGAD:91869; match to protein family HMM PF01205; hypothetical protein complement(2262913..2263524) Neisseria meningitidis MC58 903219 NP_275139.1 CDS etfA NC_003112.2 2263587 2264522 R identified by similarity to EGAD:45711; match to protein family HMM PF00766; electron transfer flavoprotein subunit alpha complement(2263587..2264522) Neisseria meningitidis MC58 903218 NP_275140.1 CDS etfB NC_003112.2 2264533 2265282 R identified by similarity to EGAD:40692; match to protein family HMM PF01012; electron transfer flavoprotein subunit beta complement(2264533..2265282) Neisseria meningitidis MC58 903217 NP_275141.1 CDS rfaC NC_003112.2 2265509 2266477 R identified by similarity to EGAD:40648; match to protein family HMM PF01075; match to protein family HMM TIGR02193; lipopolysaccharide heptosyltransferase I complement(2265509..2266477) Neisseria meningitidis MC58 903216 NP_275142.1 CDS NMB2157 NC_003112.2 2266514 2267149 R identified by similarity to EGAD:140533; match to protein family HMM PF00857; pyrazinamidase/nicotinamidase PncA complement(2266514..2267149) Neisseria meningitidis MC58 903215 NP_275143.1 CDS NMB2158 NC_003112.2 2267263 2267943 D identified by similarity to EGAD:21511; match to protein family HMM PF01980; match to protein family HMM TIGR00104; hypothetical protein 2267263..2267943 Neisseria meningitidis MC58 903214 NP_275144.1 CDS gapA-2 NC_003112.2 2268201 2269205 R identified by similarity to EGAD:22254; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde 3-phosphate dehydrogenase C complement(2268201..2269205) Neisseria meningitidis MC58 903213 NP_275145.1 CDS mutS NC_003112.2 2269649 2272243 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2269649..2272243 Neisseria meningitidis MC58 903212 NMBt01 tRNA tRNA-Lys-2 NC_003112.2 9197 9272 R tRNA-Lys complement(9197..9272) Neisseria meningitidis MC58 902114 NMBt02 tRNA tRNA-Ile-4 NC_003112.2 62614 62690 D tRNA-Ile 62614..62690 Neisseria meningitidis MC58 902160 NMBt03 tRNA tRNA-Ala-5 NC_003112.2 62696 62771 D tRNA-Ala 62696..62771 Neisseria meningitidis MC58 902161 NMBt04 tRNA tRNA-Tyr-1 NC_003112.2 131944 132027 D tRNA-Tyr 131944..132027 Neisseria meningitidis MC58 902228 NMBt05 tRNA tRNA-Gly-1 NC_003112.2 132058 132131 D tRNA-Gly 132058..132131 Neisseria meningitidis MC58 902229 NMBt06 tRNA tRNA-Thr-1 NC_003112.2 132141 132215 D tRNA-Thr 132141..132215 Neisseria meningitidis MC58 902230 NMBt07 tRNA tRNA-Trp-1 NC_003112.2 133455 133530 D tRNA-Trp 133455..133530 Neisseria meningitidis MC58 902232 NMBt08 tRNA tRNA-Thr-2 NC_003112.2 187027 187102 R tRNA-Thr complement(187027..187102) Neisseria meningitidis MC58 902296 NMBt09 tRNA tRNA-Val-1 NC_003112.2 211566 211641 D tRNA-Val 211566..211641 Neisseria meningitidis MC58 902318 NMBt10 tRNA tRNA-Asp-1 NC_003112.2 211674 211750 D tRNA-Asp 211674..211750 Neisseria meningitidis MC58 902319 NMBt11 tRNA tRNA-Val-2 NC_003112.2 211790 211865 D tRNA-Val 211790..211865 Neisseria meningitidis MC58 902320 NMBt12 tRNA tRNA-Asp-2 NC_003112.2 211898 211974 D tRNA-Asp 211898..211974 Neisseria meningitidis MC58 902321 NMBt13 tRNA tRNA-Ile-3 NC_003112.2 309364 309440 D tRNA-Ile 309364..309440 Neisseria meningitidis MC58 902411 NMBt14 tRNA tRNA-Ala-3 NC_003112.2 309446 309521 D tRNA-Ala 309446..309521 Neisseria meningitidis MC58 902412 NMBt15 tRNA tRNA-Arg-4 NC_003112.2 336974 337045 D tRNA-Arg 336974..337045 Neisseria meningitidis MC58 902443 NMBt16 tRNA tRNA-Phe-1 NC_003112.2 363887 363962 D tRNA-Phe 363887..363962 Neisseria meningitidis MC58 902472 NMBt17 tRNA tRNA-Ala-4 NC_003112.2 416289 416364 R tRNA-Ala complement(416289..416364) Neisseria meningitidis MC58 902523 NMBt18 tRNA tRNA-Met-3 NC_003112.2 416372 416448 R tRNA-Met complement(416372..416448) Neisseria meningitidis MC58 902524 NMBt19 tRNA tRNA-Asn-2 NC_003112.2 501231 501306 D tRNA-Asn 501231..501306 Neisseria meningitidis MC58 902596 NMBt20 tRNA tRNA-Pro-2 NC_003112.2 549517 549593 R tRNA-Pro complement(549517..549593) Neisseria meningitidis MC58 902645 NMBt21 tRNA tRNA-Pro-3 NC_003112.2 675416 675492 D tRNA-Pro 675416..675492 Neisseria meningitidis MC58 902754 NMBt22 tRNA tRNA-Ser-2 NC_003112.2 704825 704917 D tRNA-Ser 704825..704917 Neisseria meningitidis MC58 902789 NMBt23 tRNA tRNA-Val-3 NC_003112.2 750914 750990 D tRNA-Val 750914..750990 Neisseria meningitidis MC58 902832 NMBt24 tRNA tRNA-Arg-5 NC_003112.2 773076 773152 D tRNA-Arg 773076..773152 Neisseria meningitidis MC58 902854 NMBt25 tRNA tRNA-Glu-3 NC_003112.2 773170 773244 D tRNA-Glu 773170..773244 Neisseria meningitidis MC58 902855 NMBt26 tRNA tRNA-Thr-3 NC_003112.2 889213 889288 D tRNA-Thr 889213..889288 Neisseria meningitidis MC58 902984 NMBt27 tRNA tRNA-Thr-4 NC_003112.2 889323 889398 D tRNA-Thr 889323..889398 Neisseria meningitidis MC58 902985 NMBt28 tRNA tRNA-Gln-1 NC_003112.2 894882 894957 D tRNA-Gln 894882..894957 Neisseria meningitidis MC58 902991 NMBt29 tRNA tRNA-Gln-2 NC_003112.2 894970 895045 D tRNA-Gln 894970..895045 Neisseria meningitidis MC58 902992 NMBt30 tRNA tRNA-Gln-3 NC_003112.2 895054 895129 D tRNA-Gln 895054..895129 Neisseria meningitidis MC58 902993 NMBt31 tRNA tRNA-Ser-3 NC_003112.2 915875 915965 D tRNA-Ser 915875..915965 Neisseria meningitidis MC58 903015 NMBt32 tRNA tRNA-Ser-4 NC_003112.2 916041 916130 D tRNA-Ser 916041..916130 Neisseria meningitidis MC58 903016 NMBt33 tRNA tRNA-Ser-1 NC_003112.2 1201884 1201974 R tRNA-Ser complement(1201884..1201974) Neisseria meningitidis MC58 903619 NMBt34 tRNA tRNA-Leu-1 NC_003112.2 1202013 1202099 R tRNA-Leu complement(1202013..1202099) Neisseria meningitidis MC58 903620 NMBt35 tRNA tRNA-Leu-2 NC_003112.2 1202135 1202221 R tRNA-Leu complement(1202135..1202221) Neisseria meningitidis MC58 903621 NMBt36 tRNA tRNA-Leu-3 NC_003112.2 1260472 1260556 R tRNA-Leu complement(1260472..1260556) Neisseria meningitidis MC58 903675 NMBt37 tRNA tRNA-Arg-1 NC_003112.2 1499772 1499848 D tRNA-Arg 1499772..1499848 Neisseria meningitidis MC58 903872 NMBt38 tRNA tRNA-Glu-1 NC_003112.2 1499866 1499940 D tRNA-Glu 1499866..1499940 Neisseria meningitidis MC58 903873 NMBt39 tRNA tRNA-Asn-1 NC_003112.2 1578315 1578390 R tRNA-Asn complement(1578315..1578390) Neisseria meningitidis MC58 904032 NMBt40 tRNA tRNA-Leu-4 NC_003112.2 1640362 1640446 R tRNA-Leu complement(1640362..1640446) Neisseria meningitidis MC58 904188 NMBt41 tRNA tRNA-Leu-5 NC_003112.2 1650211 1650300 R tRNA-Leu complement(1650211..1650300) Neisseria meningitidis MC58 904240 NMBt42 tRNA tRNA-Cys-1 NC_003112.2 1650403 1650476 R tRNA-Cys complement(1650403..1650476) Neisseria meningitidis MC58 904241 NMBt43 tRNA tRNA-Gly-2 NC_003112.2 1650502 1650577 R tRNA-Gly complement(1650502..1650577) Neisseria meningitidis MC58 904242 NMBt44 tRNA tRNA-Gly-3 NC_003112.2 1650599 1650674 R tRNA-Gly complement(1650599..1650674) Neisseria meningitidis MC58 904248 NMBt45 tRNA tRNA-Gly-4 NC_003112.2 1650698 1650773 R tRNA-Gly complement(1650698..1650773) Neisseria meningitidis MC58 904251 NMBt46 tRNA tRNA-Gly-5 NC_003112.2 1650799 1650874 R tRNA-Gly complement(1650799..1650874) Neisseria meningitidis MC58 904256 NMBt47 tRNA tRNA-Glu-2 NC_003112.2 1679073 1679148 D tRNA-Glu 1679073..1679148 Neisseria meningitidis MC58 904176 NMBt48 tRNA tRNA-Ala-1 NC_003112.2 1728777 1728852 R tRNA-Ala complement(1728777..1728852) Neisseria meningitidis MC58 903457 NMBt49 tRNA tRNA-Ile-1 NC_003112.2 1728858 1728934 R tRNA-Ile complement(1728858..1728934) Neisseria meningitidis MC58 903456 NMBt50 tRNA tRNA-Arg-2 NC_003112.2 1753611 1753686 D tRNA-Arg 1753611..1753686 Neisseria meningitidis MC58 903431 NMBt51 tRNA tRNA-Met-1 NC_003112.2 1780355 1780430 D tRNA-Met 1780355..1780430 Neisseria meningitidis MC58 903399 NMBt52 tRNA tRNA-Lys-1 NC_003112.2 1944782 1944857 R tRNA-Lys complement(1944782..1944857) Neisseria meningitidis MC58 903253 NMBt53 tRNA tRNA-Leu-6 NC_003112.2 1991753 1991838 D tRNA-Leu 1991753..1991838 Neisseria meningitidis MC58 904289 NMBt54 tRNA tRNA-Ala-2 NC_003112.2 2135652 2135727 R tRNA-Ala complement(2135652..2135727) Neisseria meningitidis MC58 904096 NMBt55 tRNA tRNA-Ile-2 NC_003112.2 2135733 2135809 R tRNA-Ile complement(2135733..2135809) Neisseria meningitidis MC58 904095 NMBt56 tRNA tRNA-Met-2 NC_003112.2 2161863 2161939 D tRNA-Met 2161863..2161939 Neisseria meningitidis MC58 904051 NMBt57 tRNA tRNA-His-1 NC_003112.2 2199338 2199413 R tRNA-His complement(2199338..2199413) Neisseria meningitidis MC58 903987 NMBt58 tRNA tRNA-Arg-3 NC_003112.2 2199441 2199517 R tRNA-Arg complement(2199441..2199517) Neisseria meningitidis MC58 903985 NMBt59 tRNA tRNA-Pro-1 NC_003112.2 2199542 2199619 R tRNA-Pro complement(2199542..2199619) Neisseria meningitidis MC58 903983 NMrrnaA16S rRNA NMrrnaA16S NC_003112.2 60971 62514 D 16S ribosomal RNA 60971..62514 Neisseria meningitidis MC58 902159 NMrrnaA23S rRNA NMrrnaA23S NC_003112.2 63178 66068 D 23S ribosomal RNA 63178..66068 Neisseria meningitidis MC58 902162 NMrrnaA5S rRNA NMrrnaA5S NC_003112.2 66162 66278 D 5S ribosomal RNA 66162..66278 Neisseria meningitidis MC58 902163 NMrrnaB16S rRNA NMrrnaB16S NC_003112.2 307721 309264 D 16S ribosomal RNA 307721..309264 Neisseria meningitidis MC58 902410 NMrrnaB23S rRNA NMrrnaB23S NC_003112.2 309928 312818 D 23S ribosomal RNA 309928..312818 Neisseria meningitidis MC58 902413 NMrrnaB5S rRNA NMrrnaB5S NC_003112.2 312912 313028 D 5S ribosomal RNA 312912..313028 Neisseria meningitidis MC58 902414 NMrrnaC5S rRNA NMrrnaC5S NC_003112.2 1725270 1725386 R 5S ribosomal RNA complement(1725270..1725386) Neisseria meningitidis MC58 903458 NMrrnaC23S rRNA NMrrnaC23S NC_003112.2 1725480 1728370 R 23S ribosomal RNA complement(1725480..1728370) Neisseria meningitidis MC58 904009 NMrrnaC16S rRNA NMrrnaC16S NC_003112.2 1729034 1730577 R 16S ribosomal RNA complement(1729034..1730577) Neisseria meningitidis MC58 903455 NMrrnaD5S rRNA NMrrnaD5S NC_003112.2 2132145 2132261 R 5S ribosomal RNA complement(2132145..2132261) Neisseria meningitidis MC58 904102 NMrrnaD23S rRNA NMrrnaD23S NC_003112.2 2132355 2135245 R 23S ribosomal RNA complement(2132355..2135245) Neisseria meningitidis MC58 904100 NMrrnaD16S rRNA NMrrnaD16S NC_003112.2 2135909 2137452 R 16S ribosomal RNA complement(2135909..2137452) Neisseria meningitidis MC58 904094