-- dump date 20140619_154920 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_003029917.1 253796916 8161237 103..1626 1 NC_012943.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1626 dnaA 8161237 dnaA Mycobacterium tuberculosis KZN 1435 chromosomal replication initiation protein YP_003029917.1 103 D 478434 CDS YP_003029918.1 253796917 8163707 2154..3362 1 NC_012943.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3362 8163707 TBMG_00002 Mycobacterium tuberculosis KZN 1435 DNA polymerase III subunit beta YP_003029918.1 2154 D 478434 CDS YP_003029919.1 253796918 8163708 3382..4539 1 NC_012943.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4539 recF 8163708 recF Mycobacterium tuberculosis KZN 1435 recombination protein F YP_003029919.1 3382 D 478434 CDS YP_003029920.1 253796919 8163709 4536..5099 1 NC_012943.1 hypothetical protein 5099 8163709 TBMG_00004 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029920.1 4536 D 478434 CDS YP_003029921.1 253796920 8163710 5225..7369 1 NC_012943.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 7369 gyrB 8163710 gyrB Mycobacterium tuberculosis KZN 1435 DNA gyrase subunit B YP_003029921.1 5225 D 478434 CDS YP_003029922.1 253796921 8163711 7404..9920 1 NC_012943.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 9920 8163711 TBMG_00006 Mycobacterium tuberculosis KZN 1435 DNA gyrase subunit A YP_003029922.1 7404 D 478434 CDS YP_003029923.1 253796922 8163712 10016..10930 1 NC_012943.1 hypothetical protein 10930 8163712 TBMG_00007 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029923.1 10016 D 478434 CDS YP_003029924.1 253796923 8163715 complement(11976..12413) 1 NC_012943.1 hypothetical protein 12413 8163715 TBMG_00008 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029924.1 11976 R 478434 CDS YP_003029925.1 253796924 8163716 12570..13118 1 NC_012943.1 iron-regulated peptidyl-prolyl-cis-trans-isomerase A ppiA 13118 8163716 TBMG_00009 Mycobacterium tuberculosis KZN 1435 iron-regulated peptidyl-prolyl-cis-trans-isomerase A ppiA YP_003029925.1 12570 D 478434 CDS YP_003029926.1 253796925 8163717 complement(13235..13660) 1 NC_012943.1 hypothetical protein 13660 8163717 TBMG_00010 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029926.1 13235 R 478434 CDS YP_003029927.1 253796926 8163718 complement(13816..14097) 1 NC_012943.1 integral membrane protein involved in inhibition of the Z-ring formation; septation inhibitor protein 14097 8163718 TBMG_00011 Mycobacterium tuberculosis KZN 1435 septation inhibitor protein YP_003029927.1 13816 R 478434 CDS YP_003029928.1 253796927 8163719 14191..14979 1 NC_012943.1 hypothetical protein 14979 8163719 TBMG_00012 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029928.1 14191 D 478434 CDS YP_003029929.1 253796928 8163720 15016..15714 1 NC_012943.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 15714 8163720 TBMG_00013 Mycobacterium tuberculosis KZN 1435 para-aminobenzoate synthase component II YP_003029929.1 15016 D 478434 CDS YP_003029930.1 253796929 8163721 complement(15692..17572) 1 NC_012943.1 Ser/Thr protein kinase 17572 8163721 TBMG_00014 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003029930.1 15692 R 478434 CDS YP_003029931.1 253796930 8163722 complement(17569..18846) 1 NC_012943.1 Ser/Thr protein kinase 18846 8163722 TBMG_00015 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003029931.1 17569 R 478434 CDS YP_003029932.1 253796931 8163723 complement(18861..20336) 1 NC_012943.1 penicillin-binding protein pbpA 20336 8163723 TBMG_00016 Mycobacterium tuberculosis KZN 1435 penicillin-binding protein pbpA YP_003029932.1 18861 R 478434 CDS YP_003029933.1 253796932 8163724 complement(20333..21742) 1 NC_012943.1 cell division protein rodA 21742 8163724 TBMG_00017 Mycobacterium tuberculosis KZN 1435 cell division protein rodA YP_003029933.1 20333 R 478434 CDS YP_003029934.1 253796933 8163725 complement(21739..23283) 1 NC_012943.1 serine/threonine phosphatase ppp 23283 8163725 TBMG_00018 Mycobacterium tuberculosis KZN 1435 serine/threonine phosphatase ppp YP_003029934.1 21739 R 478434 CDS YP_003029935.1 253796934 8163726 complement(23372..23839) 1 NC_012943.1 hypothetical protein 23839 8163726 TBMG_00019 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029935.1 23372 R 478434 CDS YP_003029936.1 253796935 8163727 complement(23963..25546) 1 NC_012943.1 hypothetical protein 25546 8163727 TBMG_00020 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029936.1 23963 R 478434 CDS YP_003029937.1 253796936 8163729 complement(26015..26980) 1 NC_012943.1 hypothetical protein 26980 8163729 TBMG_00021 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029937.1 26015 R 478434 CDS YP_003029938.1 253796937 8163730 complement(27125..27544) 1 NC_012943.1 transcriptional regulator whib-like whiB5 27544 8163730 TBMG_00022 Mycobacterium tuberculosis KZN 1435 transcriptional regulator whib-like whiB5 YP_003029938.1 27125 R 478434 CDS YP_003029939.1 253796938 8163731 27697..28467 1 NC_012943.1 transcriptional regulator 28467 8163731 TBMG_00023 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003029939.1 27697 D 478434 CDS YP_003029940.1 253796939 8163732 28464..29309 1 NC_012943.1 hypothetical protein 29309 8163732 TBMG_00024 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029940.1 28464 D 478434 CDS YP_003029941.1 253796940 8163733 29347..29709 1 NC_012943.1 hypothetical protein 29709 8163733 TBMG_00025 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029941.1 29347 D 478434 CDS YP_003029942.1 253796941 8163734 29824..31170 1 NC_012943.1 hypothetical protein 31170 8163734 TBMG_00026 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029942.1 29824 D 478434 CDS YP_003029943.1 253796942 8163735 31291..31608 1 NC_012943.1 hypothetical protein 31608 8163735 TBMG_00027 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029943.1 31291 D 478434 CDS YP_003029944.1 253796943 8163736 31616..31921 1 NC_012943.1 hypothetical protein 31921 8163736 TBMG_00028 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029944.1 31616 D 478434 CDS YP_003029945.1 253796944 8163737 complement(31926..32069) 1 NC_012943.1 hypothetical protein 32069 8163737 TBMG_03973 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029945.1 31926 R 478434 CDS YP_003029946.1 253796945 8163738 32159..33256 1 NC_012943.1 hypothetical protein 33256 8163738 TBMG_00029 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029946.1 32159 D 478434 CDS YP_003029947.1 253796946 8163739 33326..33901 1 NC_012943.1 transposase 33901 8163739 TBMG_00030 Mycobacterium tuberculosis KZN 1435 transposase YP_003029947.1 33326 D 478434 CDS YP_003029948.1 253796947 8163740 34409..36643 1 NC_012943.1 8-amino-7-oxononanoate synthase 36643 8163740 TBMG_00031 Mycobacterium tuberculosis KZN 1435 8-amino-7-oxononanoate synthase YP_003029948.1 34409 D 478434 CDS YP_003029949.1 253796948 8163741 36710..36973 1 NC_012943.1 acyl carrier protein 36973 8163741 TBMG_00032 Mycobacterium tuberculosis KZN 1435 acyl carrier protein YP_003029949.1 36710 D 478434 CDS YP_003029950.1 253796949 8163742 36970..37365 1 NC_012943.1 hypothetical protein 37365 8163742 TBMG_00033 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029950.1 36970 D 478434 CDS YP_003029951.1 253796950 8163743 37362..39050 1 NC_012943.1 fatty-acid-CoA ligase fadD34 39050 8163743 TBMG_00034 Mycobacterium tuberculosis KZN 1435 fatty-acid-CoA ligase fadD34 YP_003029951.1 37362 D 478434 CDS YP_003029952.1 253796951 8163744 complement(39159..39932) 1 NC_012943.1 hypothetical protein 39932 8163744 TBMG_00035 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029952.1 39159 R 478434 CDS YP_003029953.1 253796952 8163745 complement(39980..41305) 1 NC_012943.1 hypothetical protein 41305 8163745 TBMG_00036 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029953.1 39980 R 478434 CDS YP_003029954.1 253796953 8163746 41407..42015 1 NC_012943.1 hypothetical protein 42015 8163746 TBMG_00037 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029954.1 41407 D 478434 CDS YP_003029955.1 253796954 8163747 complement(42107..42454) 1 NC_012943.1 hypothetical protein 42454 8163747 TBMG_00038 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029955.1 42107 R 478434 CDS YP_003029956.1 253796955 8163748 complement(42536..43468) 1 NC_012943.1 hypothetical protein 43468 8163748 TBMG_00039 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029956.1 42536 R 478434 CDS YP_003029957.1 253796956 8163749 43665..46574 1 NC_012943.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 46574 leuS 8163749 leuS Mycobacterium tuberculosis KZN 1435 leucyl-tRNA synthetase YP_003029957.1 43665 D 478434 CDS YP_003029958.1 253796957 8163750 complement(46684..47310) 1 NC_012943.1 transcriptional regulator, marR-family 47310 8163750 TBMG_00041 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, marR-family YP_003029958.1 46684 R 478434 CDS YP_003029959.1 253796958 8163751 complement(47469..48203) 1 NC_012943.1 GntR family transcriptional regulator 48203 8163751 TBMG_00042 Mycobacterium tuberculosis KZN 1435 GntR family transcriptional regulator YP_003029959.1 47469 R 478434 CDS YP_003029960.1 253796959 8163752 complement(48336..49130) 1 NC_012943.1 oxidoreductase 49130 8163752 TBMG_00043 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003029960.1 48336 R 478434 CDS YP_003029961.1 253796960 8163753 complement(49146..50042) 1 NC_012943.1 hydrolase 50042 8163753 TBMG_00044 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003029961.1 49146 R 478434 CDS YP_003029962.1 253796961 8163754 complement(50124..51227) 1 NC_012943.1 myo-inositol-1-phosphate synthase ino1 51227 8163754 TBMG_00045 Mycobacterium tuberculosis KZN 1435 myo-inositol-1-phosphate synthase ino1 YP_003029962.1 50124 R 478434 CDS YP_003029963.1 253796962 8163755 complement(51288..51830) 1 NC_012943.1 hypothetical protein 51830 8163755 TBMG_00046 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029963.1 51288 R 478434 CDS YP_003029964.1 253796963 8163756 complement(51931..52800) 1 NC_012943.1 hypothetical protein 52800 8163756 TBMG_00047 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029964.1 51931 R 478434 CDS YP_003029965.1 253796964 8163757 52913..53347 1 NC_012943.1 hypothetical protein 53347 8163757 TBMG_00048 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029965.1 52913 D 478434 CDS YP_003029966.1 253796965 8163758 53340..55802 1 NC_012943.1 bifunctional penicillin-binding protein ponA1 55802 8163758 TBMG_00049 Mycobacterium tuberculosis KZN 1435 bifunctional penicillin-binding protein ponA1 YP_003029966.1 53340 D 478434 CDS YP_003029967.1 253796966 8163759 55799..57481 1 NC_012943.1 hypothetical protein 57481 8163759 TBMG_00050 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029967.1 55799 D 478434 CDS YP_003029968.1 253796967 8163760 57438..58076 1 NC_012943.1 hypothetical protein 58076 8163760 TBMG_00051 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029968.1 57438 D 478434 CDS YP_003029969.1 253796968 8163761 58295..58585 1 NC_012943.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 58585 rpsF 8163761 rpsF Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S6 YP_003029969.1 58295 D 478434 CDS YP_003029970.1 253796969 8163762 58689..59183 1 NC_012943.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 59183 8163762 TBMG_00053 Mycobacterium tuberculosis KZN 1435 single-stranded DNA-binding protein YP_003029970.1 58689 D 478434 CDS YP_003029971.1 253796970 8163763 59225..59479 1 NC_012943.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 59479 rpsR 8163763 rpsR Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S18 YP_003029971.1 59225 D 478434 CDS YP_003029972.1 253796971 8163764 59512..59970 1 NC_012943.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 59970 rplI 8163764 rplI Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L9 YP_003029972.1 59512 D 478434 CDS YP_003029973.1 253796972 8163765 59999..60520 1 NC_012943.1 hypothetical protein 60520 8163765 TBMG_00056 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029973.1 59999 D 478434 CDS YP_003029974.1 253796973 8163766 60499..63123 1 NC_012943.1 unwinds double stranded DNA; these Mycobacterial enzymes appear to contain inteins; replicative DNA helicase 63123 8163766 TBMG_00057 Mycobacterium tuberculosis KZN 1435 replicative DNA helicase YP_003029974.1 60499 D 478434 CDS YP_003029975.1 253796974 8163767 63303..63995 1 NC_012943.1 hypothetical protein 63995 8163767 TBMG_00058 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029975.1 63303 D 478434 CDS YP_003029976.1 253796975 8163768 64012..65070 1 NC_012943.1 hypothetical protein 65070 8163768 TBMG_00059 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029976.1 64012 D 478434 CDS YP_003029977.1 253796976 8163769 complement(65115..65495) 1 NC_012943.1 hypothetical protein 65495 8163769 TBMG_00060 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029977.1 65115 R 478434 CDS YP_003029978.1 253796977 8163770 65655..66797 1 NC_012943.1 cellulase celA1 66797 8163770 TBMG_00061 Mycobacterium tuberculosis KZN 1435 cellulase celA1 YP_003029978.1 65655 D 478434 CDS YP_003029979.1 253796978 8163771 67026..68465 1 NC_012943.1 oxidoreductase 68465 8163771 TBMG_00062 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003029979.1 67026 D 478434 CDS YP_003029980.1 253796979 8163772 68521..68682 1 NC_012943.1 hypothetical protein 68682 8163772 TBMG_03974 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029980.1 68521 D 478434 CDS YP_003029981.1 253796980 8163773 68723..71662 1 NC_012943.1 hypothetical protein 71662 8163773 TBMG_00063 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029981.1 68723 D 478434 CDS YP_003029982.1 253796981 8163774 71729..71968 1 NC_012943.1 antitoxin 71968 8163774 TBMG_00064 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003029982.1 71729 D 478434 CDS YP_003029983.1 253796982 8163775 71961..72362 1 NC_012943.1 toxin 72362 8163775 TBMG_00065 Mycobacterium tuberculosis KZN 1435 toxin YP_003029983.1 71961 D 478434 CDS YP_003029984.1 253796983 8163776 complement(72414..74651) 1 NC_012943.1 isocitrate dehydrogenase [NADP] icd2 74651 8163776 TBMG_00066 Mycobacterium tuberculosis KZN 1435 isocitrate dehydrogenase [NADP] icd2 YP_003029984.1 72414 R 478434 CDS YP_003029985.1 253796984 8163777 complement(74769..75338) 1 NC_012943.1 TetR family transcriptional regulator 75338 8163777 TBMG_00067 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003029985.1 74769 R 478434 CDS YP_003029986.1 253796985 8163778 75441..76352 1 NC_012943.1 short chain dehydrogenase 76352 8163778 TBMG_00068 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003029986.1 75441 D 478434 CDS YP_003029987.1 253796986 8163779 complement(76377..77762) 1 NC_012943.1 L-serine dehydratase sdaA 77762 8163779 TBMG_00069 Mycobacterium tuberculosis KZN 1435 L-serine dehydratase sdaA YP_003029987.1 76377 R 478434 CDS YP_003029988.1 253796987 8163780 complement(77759..79036) 1 NC_012943.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 79036 glyA 8163780 glyA Mycobacterium tuberculosis KZN 1435 serine hydroxymethyltransferase YP_003029988.1 77759 R 478434 CDS YP_003029989.1 253796988 8163781 79626..80324 1 NC_012943.1 maturase 80324 8163781 TBMG_00071 Mycobacterium tuberculosis KZN 1435 maturase YP_003029989.1 79626 D 478434 CDS YP_003029990.1 253796989 8163782 80755..81804 1 NC_012943.1 hypothetical protein 81804 8163782 TBMG_00072 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029990.1 80755 D 478434 CDS YP_003029991.1 253796990 8163783 81807..82799 1 NC_012943.1 glutamine-transport ATP-binding protein ABC transporter 82799 8163783 TBMG_00073 Mycobacterium tuberculosis KZN 1435 glutamine-transport ATP-binding protein ABC transporter YP_003029991.1 81807 D 478434 CDS YP_003029992.1 253796991 8163784 82879..84114 1 NC_012943.1 hypothetical protein 84114 8163784 TBMG_00074 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029992.1 82879 D 478434 CDS YP_003029993.1 253796992 8163785 84127..85299 1 NC_012943.1 aminotransferase 85299 8163785 TBMG_00075 Mycobacterium tuberculosis KZN 1435 aminotransferase YP_003029993.1 84127 D 478434 CDS YP_003029994.1 253796993 8163786 complement(85314..85703) 1 NC_012943.1 hypothetical protein 85703 8163786 TBMG_00076 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029994.1 85314 R 478434 CDS YP_003029995.1 253796994 8163787 complement(85767..86621) 1 NC_012943.1 oxidoreductase 86621 8163787 TBMG_00077 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003029995.1 85767 R 478434 CDS YP_003029996.1 253796995 8162985 86659..87264 1 NC_012943.1 transcriptional regulator 87264 8162985 TBMG_00078 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003029996.1 86659 D 478434 CDS YP_003029997.1 253796996 8162986 complement(87339..87932) 1 NC_012943.1 hypothetical protein 87932 8162986 TBMG_00079 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029997.1 87339 R 478434 CDS YP_003029998.1 253796997 8162987 88335..89156 1 NC_012943.1 hypothetical protein 89156 8162987 TBMG_00080 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029998.1 88335 D 478434 CDS YP_003029999.1 253796998 8162988 89153..89611 1 NC_012943.1 hypothetical protein 89611 8162988 TBMG_00081 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003029999.1 89153 D 478434 CDS YP_003030000.1 253796999 8162989 89706..90050 1 NC_012943.1 transcriptional regulator 90050 8162989 TBMG_00082 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030000.1 89706 D 478434 CDS YP_003030001.1 253797000 8162990 90055..90534 1 NC_012943.1 oxidoreductase 90534 8162990 TBMG_00083 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030001.1 90055 D 478434 CDS YP_003030002.1 253797001 8162991 90531..92453 1 NC_012943.1 oxidoreductase 92453 8162991 TBMG_00084 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030002.1 90531 D 478434 CDS YP_003030003.1 253797002 8162992 92459..93409 1 NC_012943.1 formate hydrogenlyase hycD 93409 8162992 TBMG_00085 Mycobacterium tuberculosis KZN 1435 formate hydrogenlyase hycD YP_003030003.1 92459 D 478434 CDS YP_003030004.1 253797003 8162993 93420..94082 1 NC_012943.1 hydrogenase hycP 94082 8162993 TBMG_00086 Mycobacterium tuberculosis KZN 1435 hydrogenase hycP YP_003030004.1 93420 D 478434 CDS YP_003030005.1 253797004 8162994 94082..95548 1 NC_012943.1 hydrogenase hycQ 95548 8162994 TBMG_00087 Mycobacterium tuberculosis KZN 1435 hydrogenase hycQ YP_003030005.1 94082 D 478434 CDS YP_003030006.1 253797005 8162995 95545..97023 1 NC_012943.1 formate hydrogenase hycE 97023 8162995 TBMG_00088 Mycobacterium tuberculosis KZN 1435 formate hydrogenase hycE YP_003030006.1 95545 D 478434 CDS YP_003030007.1 253797006 8162996 97058..97732 1 NC_012943.1 hypothetical protein 97732 8162996 TBMG_00089 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030007.1 97058 D 478434 CDS YP_003030008.1 253797007 8162997 97889..98482 1 NC_012943.1 methyltransferase/methylase 98482 8162997 TBMG_00090 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030008.1 97889 D 478434 CDS YP_003030009.1 253797008 8162998 98611..99381 1 NC_012943.1 hypothetical protein 99381 8162998 TBMG_00091 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030009.1 98611 D 478434 CDS YP_003030010.1 253797009 8162999 99815..100582 1 NC_012943.1 bifunctional nucleosidase mtn 100582 8162999 TBMG_00092 Mycobacterium tuberculosis KZN 1435 bifunctional nucleosidase mtn YP_003030010.1 99815 D 478434 CDS YP_003030011.1 253797010 8163000 100714..102999 1 NC_012943.1 cation transporter P-type ATPase A ctpA 102999 8163000 TBMG_00093 Mycobacterium tuberculosis KZN 1435 cation transporter P-type ATPase A ctpA YP_003030011.1 100714 D 478434 CDS YP_003030012.1 253797011 8163001 complement(102946..103794) 1 NC_012943.1 hypothetical protein 103794 8163001 TBMG_00094 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030012.1 102946 R 478434 CDS YP_003030013.1 253797012 8163002 complement(103841..104800) 1 NC_012943.1 hypothetical protein 104800 8163002 TBMG_00095 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030013.1 103841 R 478434 CDS YP_003030014.1 253797013 8163003 complement(104936..105346) 1 NC_012943.1 hypothetical protein 105346 8163003 TBMG_00096 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030014.1 104936 R 478434 CDS YP_003030015.1 253797014 8163004 105455..106846 1 NC_012943.1 PPE family protein 106846 8163004 TBMG_00097 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030015.1 105455 D 478434 CDS YP_003030016.1 253797015 8163005 106865..107734 1 NC_012943.1 oxidoreductase 107734 8163005 TBMG_00098 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030016.1 106865 D 478434 CDS YP_003030017.1 253797016 8163006 107731..108282 1 NC_012943.1 hypothetical protein 108282 8163006 TBMG_00099 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030017.1 107731 D 478434 CDS YP_003030018.1 253797017 8163007 108287..109909 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 109909 8163007 TBMG_00100 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030018.1 108287 D 478434 CDS YP_003030019.1 253797018 8163008 109914..110150 1 NC_012943.1 hypothetical protein 110150 8163008 TBMG_00101 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030019.1 109914 D 478434 CDS YP_003030020.1 253797019 8163009 110132..117670 1 NC_012943.1 peptide synthetase nrp 117670 8163009 TBMG_00102 Mycobacterium tuberculosis KZN 1435 peptide synthetase nrp YP_003030020.1 110132 D 478434 CDS YP_003030021.1 253797020 8163010 117845..119830 1 NC_012943.1 hypothetical protein 119830 8163010 TBMG_00103 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030021.1 117845 D 478434 CDS YP_003030022.1 253797021 8163011 complement(120046..122304) 1 NC_012943.1 cation-transporter P-type ATPase B ctpB 122304 8163011 TBMG_00104 Mycobacterium tuberculosis KZN 1435 cation-transporter P-type ATPase B ctpB YP_003030022.1 120046 R 478434 CDS YP_003030023.1 253797022 8163012 122448..123962 1 NC_012943.1 hypothetical protein 123962 8163012 TBMG_00105 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030023.1 122448 D 478434 CDS YP_003030024.1 253797023 8163013 complement(124111..124395) 1 NC_012943.1 required for 70S ribosome assembly; 50S ribosomal protein L28 124395 rpmB 8163013 rpmB Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L28 YP_003030024.1 124111 R 478434 CDS YP_003030025.1 253797024 8163014 124505..125701 1 NC_012943.1 hypothetical protein 125701 8163014 TBMG_00107 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030025.1 124505 D 478434 CDS YP_003030026.1 253797025 8163015 complement(125796..130673) 1 NC_012943.1 cation-transporting ATPase 130673 8163015 TBMG_00108 Mycobacterium tuberculosis KZN 1435 cation-transporting ATPase YP_003030026.1 125796 R 478434 CDS YP_003030027.1 253797026 8163016 complement(131027..131260) 1 NC_012943.1 hypothetical protein 131260 8163016 TBMG_00109 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030027.1 131027 R 478434 CDS YP_003030028.1 253797027 8163017 131404..133005 1 NC_012943.1 PE-PGRS family protein 133005 8163017 TBMG_00110 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030028.1 131404 D 478434 CDS YP_003030029.1 253797028 8163018 133048..133902 1 NC_012943.1 hypothetical protein 133902 8163018 TBMG_00111 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030029.1 133048 D 478434 CDS YP_003030030.1 253797029 8163019 134083..136140 1 NC_012943.1 transmembrane acyltransferase 136140 8163019 TBMG_00112 Mycobacterium tuberculosis KZN 1435 transmembrane acyltransferase YP_003030030.1 134083 D 478434 CDS YP_003030031.1 253797030 8163020 136422..137378 1 NC_012943.1 GDP-mannose 4,6-dehydratase gca 137378 8163020 TBMG_00113 Mycobacterium tuberculosis KZN 1435 GDP-mannose 4,6-dehydratase gca YP_003030031.1 136422 D 478434 CDS YP_003030032.1 253797031 8163021 137452..138042 1 NC_012943.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 138042 8163021 TBMG_00114 Mycobacterium tuberculosis KZN 1435 phosphoheptose isomerase YP_003030032.1 137452 D 478434 CDS YP_003030033.1 253797032 8163022 138074..138646 1 NC_012943.1 D-alpha,beta-D-heptose-1,7-biphosphate phosphatase gmhB 138646 8163022 TBMG_00115 Mycobacterium tuberculosis KZN 1435 D-alpha,beta-D-heptose-1,7-biphosphate phosphatase gmhB YP_003030033.1 138074 D 478434 CDS YP_003030034.1 253797033 8163023 138646..139806 1 NC_012943.1 D-alpha-D-heptose-7-phosphate kinase hddA 139806 8163023 TBMG_00116 Mycobacterium tuberculosis KZN 1435 D-alpha-D-heptose-7-phosphate kinase hddA YP_003030034.1 138646 D 478434 CDS YP_003030035.1 253797034 8163024 complement(140400..141155) 1 NC_012943.1 hypothetical protein 141155 8163024 TBMG_00117 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030035.1 140400 R 478434 CDS YP_003030036.1 253797035 8163025 141327..142277 1 NC_012943.1 oxidative stress response regulatory protein oxyS 142277 8163025 TBMG_00118 Mycobacterium tuberculosis KZN 1435 oxidative stress response regulatory protein oxyS YP_003030036.1 141327 D 478434 CDS YP_003030037.1 253797036 8163026 complement(142261..144018) 1 NC_012943.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 144018 8163026 TBMG_00119 Mycobacterium tuberculosis KZN 1435 oxalyl-CoA decarboxylase YP_003030037.1 142261 R 478434 CDS YP_003030038.1 253797037 8163027 144131..145759 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 145759 8163027 TBMG_00120 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030038.1 144131 D 478434 CDS YP_003030039.1 253797038 8163028 complement(145760..147904) 1 NC_012943.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 147904 8163028 TBMG_00121 Mycobacterium tuberculosis KZN 1435 elongation factor G YP_003030039.1 145760 R 478434 CDS YP_003030040.1 253797039 8163029 complement(148041..148475) 1 NC_012943.1 F420-dependent enzyme 148475 8163029 TBMG_00122 Mycobacterium tuberculosis KZN 1435 F420-dependent enzyme YP_003030040.1 148041 R 478434 CDS YP_003030041.1 253797040 8163030 148624..148992 1 NC_012943.1 hypothetical protein 148992 8163030 TBMG_00123 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030041.1 148624 D 478434 CDS YP_003030042.1 253797041 8163031 148989..149357 1 NC_012943.1 hypothetical protein 149357 8163031 TBMG_00124 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030042.1 148989 D 478434 CDS YP_003030043.1 253797042 8163032 149624..150769 1 NC_012943.1 PE-PGRS family protein 150769 8163032 TBMG_03975 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030043.1 149624 D 478434 CDS YP_003030044.1 253797043 8163033 150714..151310 1 NC_012943.1 PE-PGRS family protein 151310 8163033 TBMG_03976 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030044.1 150714 D 478434 CDS YP_003030045.1 253797044 8163034 151501..152529 1 NC_012943.1 serine protease pepA 152529 8163034 TBMG_00126 Mycobacterium tuberculosis KZN 1435 serine protease pepA YP_003030045.1 151501 D 478434 CDS YP_003030046.1 253797045 8163035 152638..154443 1 NC_012943.1 trehalose synthase treS 154443 8163035 TBMG_00127 Mycobacterium tuberculosis KZN 1435 trehalose synthase treS YP_003030046.1 152638 D 478434 CDS YP_003030047.1 253797046 8163036 154493..155860 1 NC_012943.1 hypothetical protein 155860 8163036 TBMG_00128 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030047.1 154493 D 478434 CDS YP_003030048.1 253797047 8163037 155928..156707 1 NC_012943.1 hypothetical protein 156707 8163037 TBMG_00129 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030048.1 155928 D 478434 CDS YP_003030049.1 253797048 8163038 complement(156839..157861) 1 NC_012943.1 secreted fibronectin-binding protein C antigen 85-C fbpC 157861 8163038 TBMG_00130 Mycobacterium tuberculosis KZN 1435 secreted fibronectin-binding protein C antigen 85-C fbpC YP_003030049.1 156839 R 478434 CDS YP_003030050.1 253797049 8163039 158108..158563 1 NC_012943.1 hypothetical protein 158563 8163039 TBMG_00131 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030050.1 158108 D 478434 CDS YP_003030051.1 253797050 8163040 complement(158576..159919) 1 NC_012943.1 acyl-CoA dehydrogenase 159919 8163040 TBMG_00132 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030051.1 158576 R 478434 CDS YP_003030052.1 253797051 8163041 complement(159961..161043) 1 NC_012943.1 F420-dependent glucose-6-phosphate dehydrogenase 161043 8163041 TBMG_00133 Mycobacterium tuberculosis KZN 1435 F420-dependent glucose-6-phosphate dehydrogenase YP_003030052.1 159961 R 478434 CDS YP_003030053.1 253797052 8163042 161130..161735 1 NC_012943.1 acetyltransferase 161735 8163042 TBMG_00134 Mycobacterium tuberculosis KZN 1435 acetyltransferase YP_003030053.1 161130 D 478434 CDS YP_003030054.1 253797053 8163043 162032..162934 1 NC_012943.1 epoxide hydrolase ephF 162934 8163043 TBMG_00135 Mycobacterium tuberculosis KZN 1435 epoxide hydrolase ephF YP_003030054.1 162032 D 478434 CDS YP_003030055.1 253797054 8163044 complement(162905..163510) 1 NC_012943.1 transcriptional regulator 163510 8163044 TBMG_00136 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030055.1 162905 R 478434 CDS YP_003030056.1 253797055 8163045 163627..164952 1 NC_012943.1 cytochrome P450 138 cyp138 164952 8163045 TBMG_00137 Mycobacterium tuberculosis KZN 1435 cytochrome P450 138 cyp138 YP_003030056.1 163627 D 478434 CDS YP_003030057.1 253797056 8163046 complement(164973..165521) 1 NC_012943.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 165521 8163046 TBMG_00138 Mycobacterium tuberculosis KZN 1435 methionine sulfoxide reductase A YP_003030057.1 164973 R 478434 CDS YP_003030058.1 253797057 8163047 165584..166087 1 NC_012943.1 hypothetical protein 166087 8163047 TBMG_00139 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030058.1 165584 D 478434 CDS YP_003030059.1 253797058 8163048 166088..167110 1 NC_012943.1 oxidoreductase 167110 8163048 TBMG_00140 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030059.1 166088 D 478434 CDS YP_003030060.1 253797059 8163049 167171..167551 1 NC_012943.1 hypothetical protein 167551 8163049 TBMG_00141 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030060.1 167171 D 478434 CDS YP_003030061.1 253797060 8163050 complement(167532..167942) 1 NC_012943.1 hypothetical protein 167942 8163050 TBMG_00142 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030061.1 167532 R 478434 CDS YP_003030062.1 253797061 8163051 167972..168898 1 NC_012943.1 hypothetical protein 168898 8163051 TBMG_00143 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030062.1 167972 D 478434 CDS YP_003030063.1 253797062 8163052 complement(168965..170443) 1 NC_012943.1 hypothetical protein 170443 8163052 TBMG_00144 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030063.1 168965 R 478434 CDS YP_003030064.1 253797063 8163053 170545..171387 1 NC_012943.1 TetR family transcriptional regulator 171387 8163053 TBMG_00145 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030064.1 170545 D 478434 CDS YP_003030065.1 253797064 8163054 171476..171733 1 NC_012943.1 hypothetical protein 171733 8163054 TBMG_00146 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030065.1 171476 D 478434 CDS YP_003030066.1 253797065 8163055 171742..172107 1 NC_012943.1 hypothetical protein 172107 8163055 TBMG_03977 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030066.1 171742 D 478434 CDS YP_003030067.1 253797066 8163056 172141..173082 1 NC_012943.1 hypothetical protein 173082 8163056 TBMG_00147 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030067.1 172141 D 478434 CDS YP_003030068.1 253797067 8163057 173177..174697 1 NC_012943.1 aldehyde dehydrogenase 174697 8163057 TBMG_00148 Mycobacterium tuberculosis KZN 1435 aldehyde dehydrogenase YP_003030068.1 173177 D 478434 CDS YP_003030069.1 253797068 8163058 174772..175632 1 NC_012943.1 short-chain type dehydrogenase/reductase 175632 8163058 TBMG_00149 Mycobacterium tuberculosis KZN 1435 short-chain type dehydrogenase/reductase YP_003030069.1 174772 D 478434 CDS YP_003030070.1 253797069 8163059 175639..176607 1 NC_012943.1 quinone oxidoreductase 176607 8163059 TBMG_00150 Mycobacterium tuberculosis KZN 1435 quinone oxidoreductase YP_003030070.1 175639 D 478434 CDS YP_003030071.1 253797070 8163060 complement(176604..176891) 1 NC_012943.1 hypothetical protein 176891 8163060 TBMG_00151 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030071.1 176604 R 478434 CDS YP_003030072.1 253797071 8163061 complement(177482..179248) 1 NC_012943.1 PE family protein 179248 8163061 TBMG_00152 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003030072.1 177482 R 478434 CDS YP_003030073.1 253797072 8163062 complement(179258..180859) 1 NC_012943.1 PE family protein 180859 8163062 TBMG_00153 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003030073.1 179258 R 478434 CDS YP_003030074.1 253797073 8163063 complement(181094..181924) 1 NC_012943.1 phosphotyrosine protein phosphatase ptpb 181924 8163063 TBMG_00154 Mycobacterium tuberculosis KZN 1435 phosphotyrosine protein phosphatase ptpb YP_003030074.1 181094 R 478434 CDS YP_003030075.1 253797074 8163788 complement(181926..183149) 1 NC_012943.1 acyl-CoA dehydrogenase 183149 8163788 TBMG_00155 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030075.1 181926 R 478434 CDS YP_003030076.1 253797075 8163789 183354..183500 1 NC_012943.1 response regulator receiver domain-containing protein 183500 8163789 TBMG_03978 Mycobacterium tuberculosis KZN 1435 response regulator receiver domain-containing protein YP_003030076.1 183354 D 478434 CDS YP_003030077.1 253797076 8163790 183561..184661 1 NC_012943.1 NAD(P) transhydrogenase alpha subunit pntAa 184661 8163790 TBMG_00156 Mycobacterium tuberculosis KZN 1435 NAD(P) transhydrogenase alpha subunit pntAa YP_003030077.1 183561 D 478434 CDS YP_003030078.1 253797077 8163791 184662..184994 1 NC_012943.1 NAD(P) transhydrogenase alpha subunit pntAb 184994 8163791 TBMG_00157 Mycobacterium tuberculosis KZN 1435 NAD(P) transhydrogenase alpha subunit pntAb YP_003030078.1 184662 D 478434 CDS YP_003030079.1 253797078 8163792 184991..186418 1 NC_012943.1 NAD(P) transhydrogenase beta subunit pntB 186418 8163792 TBMG_00158 Mycobacterium tuberculosis KZN 1435 NAD(P) transhydrogenase beta subunit pntB YP_003030079.1 184991 D 478434 CDS YP_003030080.1 253797079 8163793 complement(186434..186559) 1 NC_012943.1 hypothetical protein 186559 8163793 TBMG_03979 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030080.1 186434 R 478434 CDS YP_003030081.1 253797080 8163794 186724..187368 1 NC_012943.1 TetR family transcriptional regulator 187368 8163794 TBMG_00159 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030081.1 186724 D 478434 CDS YP_003030082.1 253797081 8161809 complement(187372..188778) 1 NC_012943.1 PE family protein 188778 8161809 TBMG_00160 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003030082.1 187372 R 478434 CDS YP_003030083.1 253797082 8161810 complement(188870..190378) 1 NC_012943.1 PE family protein 190378 8161810 TBMG_00161 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003030083.1 188870 R 478434 CDS YP_003030084.1 253797083 8161811 190546..191895 1 NC_012943.1 oxidoreductase 191895 8161811 TBMG_00162 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030084.1 190546 D 478434 CDS YP_003030085.1 253797084 8161812 complement(191923..193074) 1 NC_012943.1 zinc-type alcohol dehydrogenase E subunit adhE 193074 8161812 TBMG_00163 Mycobacterium tuberculosis KZN 1435 zinc-type alcohol dehydrogenase E subunit adhE YP_003030085.1 191923 R 478434 CDS YP_003030086.1 253797085 8161814 193056..193511 1 NC_012943.1 hypothetical protein 193511 8161814 TBMG_00164 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030086.1 193056 D 478434 CDS YP_003030087.1 253797086 8161813 193565..194050 1 NC_012943.1 hypothetical protein 194050 8161813 TBMG_00165 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030087.1 193565 D 478434 CDS YP_003030088.1 253797087 8161815 complement(194083..194877) 1 NC_012943.1 GntR family transcriptional regulator 194877 8161815 TBMG_00166 Mycobacterium tuberculosis KZN 1435 GntR family transcriptional regulator YP_003030088.1 194083 R 478434 CDS YP_003030089.1 253797088 8161816 194932..196596 1 NC_012943.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 196596 8161816 TBMG_00167 Mycobacterium tuberculosis KZN 1435 long-chain-fatty-acid--CoA ligase YP_003030089.1 194932 D 478434 CDS YP_003030090.1 253797089 8161817 196800..197597 1 NC_012943.1 hypothetical protein 197597 8161817 TBMG_00168 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030090.1 196800 D 478434 CDS YP_003030091.1 253797090 8161818 197599..198468 1 NC_012943.1 hypothetical protein 198468 8161818 TBMG_00169 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030091.1 197599 D 478434 CDS YP_003030092.1 253797091 8161819 198473..199837 1 NC_012943.1 MCE-family protein mce1A 199837 8161819 TBMG_00170 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce1A YP_003030092.1 198473 D 478434 CDS YP_003030093.1 253797092 8161820 199834..200874 1 NC_012943.1 MCE-family protein mce1B 200874 8161820 TBMG_00171 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce1B YP_003030093.1 199834 D 478434 CDS YP_003030094.1 253797093 8161821 200913..202418 1 NC_012943.1 MCE-family protein mce1C 202418 8161821 TBMG_00172 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce1C YP_003030094.1 200913 D 478434 CDS YP_003030095.1 253797094 8161822 202415..204007 1 NC_012943.1 MCE-family protein mce1D 204007 8161822 TBMG_00173 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce1D YP_003030095.1 202415 D 478434 CDS YP_003030096.1 253797095 8161823 204007..205176 1 NC_012943.1 MCE-family lipoprotein mce1E 205176 8161823 TBMG_00174 Mycobacterium tuberculosis KZN 1435 MCE-family lipoprotein mce1E YP_003030096.1 204007 D 478434 CDS YP_003030097.1 253797096 8161824 205170..206717 1 NC_012943.1 MCE-family protein mce1F 206717 8161824 TBMG_00175 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce1F YP_003030097.1 205170 D 478434 CDS YP_003030098.1 253797097 8161825 206753..207394 1 NC_012943.1 hypothetical protein 207394 8161825 TBMG_00176 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030098.1 206753 D 478434 CDS YP_003030099.1 253797098 8161826 207397..208359 1 NC_012943.1 hypothetical protein 208359 8161826 TBMG_00177 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030099.1 207397 D 478434 CDS YP_003030100.1 253797099 8161827 208356..208910 1 NC_012943.1 MCE-associated protein 208910 8161827 TBMG_00178 Mycobacterium tuberculosis KZN 1435 MCE-associated protein YP_003030100.1 208356 D 478434 CDS YP_003030101.1 253797100 8161828 208877..209611 1 NC_012943.1 hypothetical protein 209611 8161828 TBMG_00179 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030101.1 208877 D 478434 CDS YP_003030102.1 253797101 8161829 complement(209642..210751) 1 NC_012943.1 hypothetical protein 210751 8161829 TBMG_00180 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030102.1 209642 R 478434 CDS YP_003030103.1 253797102 8161830 complement(210831..212189) 1 NC_012943.1 hypothetical protein 212189 8161830 TBMG_00181 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030103.1 210831 R 478434 CDS YP_003030104.1 253797103 8161831 complement(212216..212950) 1 NC_012943.1 hypothetical protein 212950 8161831 TBMG_00182 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030104.1 212216 R 478434 CDS YP_003030105.1 253797104 8161832 complement(212967..214079) 1 NC_012943.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 214079 8161832 TBMG_00183 Mycobacterium tuberculosis KZN 1435 RNA polymerase factor sigma-70 YP_003030105.1 212967 R 478434 CDS YP_003030106.1 253797105 8161834 214027..214866 1 NC_012943.1 lysophospholipase 214866 8161834 TBMG_00184 Mycobacterium tuberculosis KZN 1435 lysophospholipase YP_003030106.1 214027 D 478434 CDS YP_003030107.1 253797106 8161833 214908..215657 1 NC_012943.1 hypothetical protein 215657 8161833 TBMG_00185 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030107.1 214908 D 478434 CDS YP_003030108.1 253797107 8161835 215654..216163 1 NC_012943.1 hypothetical protein 216163 8161835 TBMG_00186 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030108.1 215654 D 478434 CDS YP_003030109.1 253797108 8161836 216208..218283 1 NC_012943.1 beta-glucosidase bglS 218283 8161836 TBMG_00187 Mycobacterium tuberculosis KZN 1435 beta-glucosidase bglS YP_003030109.1 216208 D 478434 CDS YP_003030110.1 253797109 8161837 218644..219306 1 NC_012943.1 O-methyltransferase 219306 8161837 TBMG_00188 Mycobacterium tuberculosis KZN 1435 O-methyltransferase YP_003030110.1 218644 D 478434 CDS YP_003030111.1 253797110 8161838 219425..219856 1 NC_012943.1 hypothetical protein 219856 8161838 TBMG_00189 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030111.1 219425 D 478434 CDS YP_003030112.1 253797111 8161839 complement(219935..221662) 1 NC_012943.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 221662 8161839 TBMG_00190 Mycobacterium tuberculosis KZN 1435 dihydroxy-acid dehydratase YP_003030112.1 219935 R 478434 CDS YP_003030113.1 253797112 8161840 221810..222100 1 NC_012943.1 hypothetical protein 222100 8161840 TBMG_00191 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030113.1 221810 D 478434 CDS YP_003030114.1 253797113 8161841 222228..223469 1 NC_012943.1 hypothetical protein 223469 8161841 TBMG_00192 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030114.1 222228 D 478434 CDS YP_003030115.1 253797114 8161842 223503..224603 1 NC_012943.1 hypothetical protein 224603 8161842 TBMG_00193 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030115.1 223503 D 478434 CDS YP_003030116.1 253797115 8161843 complement(224663..226510) 1 NC_012943.1 hypothetical protein 226510 8161843 TBMG_00194 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030116.1 224663 R 478434 CDS YP_003030117.1 253797116 8161844 226817..230401 1 NC_012943.1 drugs-transport transmembrane ATP-binding protein ABC transporter 230401 8161844 TBMG_00195 Mycobacterium tuberculosis KZN 1435 drugs-transport transmembrane ATP-binding protein ABC transporter YP_003030117.1 226817 D 478434 CDS YP_003030118.1 253797117 8161845 230775..231473 1 NC_012943.1 two component system transcriptional regulator, luxR-family 231473 8161845 TBMG_00196 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator, luxR-family YP_003030118.1 230775 D 478434 CDS YP_003030119.1 253797118 8161846 231586..232170 1 NC_012943.1 transcriptional regulator 232170 8161846 TBMG_00197 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030119.1 231586 D 478434 CDS YP_003030120.1 253797119 8161847 232167..234416 1 NC_012943.1 oxidoreductase 234416 8161847 TBMG_00198 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030120.1 232167 D 478434 CDS YP_003030121.1 253797120 8161848 complement(234457..236448) 1 NC_012943.1 zinc metalloprotease 236448 8161848 TBMG_00199 Mycobacterium tuberculosis KZN 1435 zinc metalloprotease YP_003030121.1 234457 R 478434 CDS YP_003030122.1 253797121 8161849 236491..237150 1 NC_012943.1 hypothetical protein 237150 8161849 TBMG_00200 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030122.1 236491 D 478434 CDS YP_003030123.1 253797122 8161850 237147..237836 1 NC_012943.1 hypothetical protein 237836 8161850 TBMG_00201 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030123.1 237147 D 478434 CDS YP_003030124.1 253797123 8161851 complement(237833..238330) 1 NC_012943.1 hypothetical protein 238330 8161851 TBMG_00202 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030124.1 237833 R 478434 CDS YP_003030125.1 253797124 8161852 complement(238333..241233) 1 NC_012943.1 transmembrane transporter mmpL11 241233 8161852 TBMG_00203 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL11 YP_003030125.1 238333 R 478434 CDS YP_003030126.1 253797125 8161853 241455..241865 1 NC_012943.1 hypothetical protein 241865 8161853 TBMG_00204 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030126.1 241455 D 478434 CDS YP_003030127.1 253797126 8161854 complement(241917..243200) 1 NC_012943.1 hypothetical protein 243200 8161854 TBMG_00205 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030127.1 241917 R 478434 CDS YP_003030128.1 253797127 8161855 243325..244428 1 NC_012943.1 hypothetical protein 244428 8161855 TBMG_00206 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030128.1 243325 D 478434 CDS YP_003030129.1 253797128 8161856 complement(244425..247259) 1 NC_012943.1 transmembrane transporter mmpL3 247259 8161856 TBMG_00207 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL3 YP_003030129.1 244425 R 478434 CDS YP_003030130.1 253797129 8161857 complement(247325..248059) 1 NC_012943.1 hypothetical protein 248059 8161857 TBMG_00208 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030130.1 247325 R 478434 CDS YP_003030131.1 253797130 8161858 complement(248056..248847) 1 NC_012943.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 248847 trmB 8161858 trmB Mycobacterium tuberculosis KZN 1435 tRNA (guanine-N(7)-)-methyltransferase YP_003030131.1 248056 R 478434 CDS YP_003030132.1 253797131 8161859 248979..250064 1 NC_012943.1 hypothetical protein 250064 8161859 TBMG_00210 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030132.1 248979 D 478434 CDS YP_003030133.1 253797132 8161860 250061..251539 1 NC_012943.1 hypothetical protein 251539 8161860 TBMG_00211 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030133.1 250061 D 478434 CDS YP_003030134.1 253797133 8161861 251723..253543 1 NC_012943.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 253543 8161861 TBMG_00212 Mycobacterium tuberculosis KZN 1435 phosphoenolpyruvate carboxykinase YP_003030134.1 251723 D 478434 CDS YP_003030135.1 253797134 8161862 complement(253610..254581) 1 NC_012943.1 AsnC family transcriptional regulator 254581 8161862 TBMG_00213 Mycobacterium tuberculosis KZN 1435 AsnC family transcriptional regulator YP_003030135.1 253610 R 478434 CDS YP_003030136.1 253797135 8161863 complement(254578..255909) 1 NC_012943.1 methyltransferase/methylase 255909 8161863 TBMG_00214 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030136.1 254578 R 478434 CDS YP_003030137.1 253797136 8161864 256005..257618 1 NC_012943.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 257618 8161864 TBMG_00215 Mycobacterium tuberculosis KZN 1435 long-chain-fatty-acid--CoA ligase YP_003030137.1 256005 D 478434 CDS YP_003030138.1 253797137 8161865 complement(257724..258845) 1 NC_012943.1 acyl-CoA dehydrogenase 258845 8161865 TBMG_00216 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030138.1 257724 R 478434 CDS YP_003030139.1 253797138 8161866 258854..259867 1 NC_012943.1 hypothetical protein 259867 8161866 TBMG_00217 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030139.1 258854 D 478434 CDS YP_003030140.1 253797139 8161867 complement(259864..260772) 1 NC_012943.1 esterase lipW 260772 8161867 TBMG_00218 Mycobacterium tuberculosis KZN 1435 esterase lipW YP_003030140.1 259864 R 478434 CDS YP_003030141.1 253797140 8161868 260865..262193 1 NC_012943.1 hypothetical protein 262193 8161868 TBMG_00219 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030141.1 260865 D 478434 CDS YP_003030142.1 253797141 8161869 262195..262743 1 NC_012943.1 hypothetical protein 262743 8161869 TBMG_00220 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030142.1 262195 D 478434 CDS YP_003030143.1 253797142 8161870 262753..263964 1 NC_012943.1 esterase lipC 263964 8161870 TBMG_00221 Mycobacterium tuberculosis KZN 1435 esterase lipC YP_003030143.1 262753 D 478434 CDS YP_003030144.1 253797143 8161871 264008..265417 1 NC_012943.1 hypothetical protein 265417 8161871 TBMG_00222 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030144.1 264008 D 478434 CDS YP_003030145.1 253797144 8161872 265448..266236 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 266236 8161872 TBMG_00223 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003030145.1 265448 D 478434 CDS YP_003030146.1 253797145 8161873 complement(266242..267705) 1 NC_012943.1 aldehyde dehydrogenase 267705 8161873 TBMG_00224 Mycobacterium tuberculosis KZN 1435 aldehyde dehydrogenase YP_003030146.1 266242 R 478434 CDS YP_003030147.1 253797146 8161874 complement(267804..268568) 1 NC_012943.1 methyltransferase/methylase 268568 8161874 TBMG_00225 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030147.1 267804 R 478434 CDS YP_003030148.1 253797147 8161875 268604..269758 1 NC_012943.1 hypothetical protein 269758 8161875 TBMG_00226 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030148.1 268604 D 478434 CDS YP_003030149.1 253797148 8161876 complement(269775..271505) 1 NC_012943.1 hypothetical protein 271505 8161876 TBMG_00227 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030149.1 269775 R 478434 CDS YP_003030150.1 253797149 8161877 complement(271515..272780) 1 NC_012943.1 hypothetical protein 272780 8161877 TBMG_00228 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030150.1 271515 R 478434 CDS YP_003030151.1 253797150 8161878 272996..274219 1 NC_012943.1 membrane acyltransferase 274219 8161878 TBMG_00229 Mycobacterium tuberculosis KZN 1435 membrane acyltransferase YP_003030151.1 272996 D 478434 CDS YP_003030152.1 253797151 8161879 complement(274247..274660) 1 NC_012943.1 toxin 274660 8161879 TBMG_03980 Mycobacterium tuberculosis KZN 1435 toxin YP_003030152.1 274247 R 478434 CDS YP_003030153.1 253797152 8161880 complement(274651..274845) 1 NC_012943.1 hypothetical protein 274845 8161880 TBMG_03981 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030153.1 274651 R 478434 CDS YP_003030154.1 253797153 8161881 complement(274924..275904) 1 NC_012943.1 phosphotriesterase php 275904 8161881 TBMG_00231 Mycobacterium tuberculosis KZN 1435 phosphotriesterase php YP_003030154.1 274924 R 478434 CDS YP_003030155.1 253797154 8161882 275999..277705 1 NC_012943.1 acyl-CoA dehydrogenase 277705 8161882 TBMG_00232 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030155.1 275999 D 478434 CDS YP_003030156.1 253797155 8161883 277840..278529 1 NC_012943.1 TetR family transcriptional regulator 278529 8161883 TBMG_00233 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030156.1 277840 D 478434 CDS YP_003030157.1 253797156 8161884 278526..279470 1 NC_012943.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit beta 279470 8161884 TBMG_00234 Mycobacterium tuberculosis KZN 1435 ribonucleotide-diphosphate reductase subunit beta YP_003030157.1 278526 D 478434 CDS YP_003030158.1 253797157 8161885 complement(279546..281081) 1 NC_012943.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase 281081 gabD1 8161885 gabD1 Mycobacterium tuberculosis KZN 1435 succinic semialdehyde dehydrogenase YP_003030158.1 279546 R 478434 CDS YP_003030159.1 253797158 8161886 complement(281107..282555) 1 NC_012943.1 hypothetical protein 282555 8161886 TBMG_00236 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030159.1 281107 R 478434 CDS YP_003030160.1 253797159 8161887 complement(282590..286792) 1 NC_012943.1 hypothetical protein 286792 8161887 TBMG_00237 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030160.1 282590 R 478434 CDS YP_003030161.1 253797160 8161888 complement(286839..287012) 1 NC_012943.1 hypothetical protein 287012 8161888 TBMG_00238 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030161.1 286839 R 478434 CDS YP_003030162.1 253797161 8162332 287127..288293 1 NC_012943.1 hypothetical protein 288293 8162332 TBMG_00239 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030162.1 287127 D 478434 CDS YP_003030163.1 253797162 8162412 288369..288983 1 NC_012943.1 TetR family transcriptional regulator 288983 8162412 TBMG_00240 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030163.1 288369 D 478434 CDS YP_003030164.1 253797163 8162413 289045..289278 1 NC_012943.1 antitoxin 289278 8162413 TBMG_00241 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030164.1 289045 D 478434 CDS YP_003030165.1 253797164 8162414 289286..289723 1 NC_012943.1 toxin 289723 8162414 TBMG_00242 Mycobacterium tuberculosis KZN 1435 toxin YP_003030165.1 289286 D 478434 CDS YP_003030166.1 253797165 8162415 complement(289753..290595) 1 NC_012943.1 hypothetical protein 290595 8162415 TBMG_00243 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030166.1 289753 R 478434 CDS YP_003030167.1 253797166 8162416 complement(290606..291970) 1 NC_012943.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 291970 fabG 8162416 fabG Mycobacterium tuberculosis KZN 1435 3-ketoacyl-ACP reductase YP_003030167.1 290606 R 478434 CDS YP_003030168.1 253797167 8162417 292112..293434 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 293434 8162417 TBMG_00245 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003030168.1 292112 D 478434 CDS YP_003030169.1 253797168 8162418 complement(293738..295573) 1 NC_012943.1 acyl-CoA dehydrogenase 295573 8162418 TBMG_00246 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030169.1 293738 R 478434 CDS YP_003030170.1 253797169 8162419 295945..296433 1 NC_012943.1 oxidoreductase 296433 8162419 TBMG_00247 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030170.1 295945 D 478434 CDS YP_003030171.1 253797170 8162420 296749..298059 1 NC_012943.1 hypothetical protein 298059 8162420 TBMG_00248 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030171.1 296749 D 478434 CDS YP_003030172.1 253797171 8162421 complement(298056..298802) 1 NC_012943.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; fumarate reductase iron-sulfur subunit 298802 8162421 TBMG_00249 Mycobacterium tuberculosis KZN 1435 fumarate reductase iron-sulfur subunit YP_003030172.1 298056 R 478434 CDS YP_003030173.1 253797172 8162422 complement(298803..300743) 1 NC_012943.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 300743 sdhA 8162422 sdhA Mycobacterium tuberculosis KZN 1435 succinate dehydrogenase flavoprotein subunit YP_003030173.1 298803 R 478434 CDS YP_003030174.1 253797173 8162423 complement(300774..301595) 1 NC_012943.1 succinate dehydrogenase membrane anchor subunit 301595 8162423 TBMG_00251 Mycobacterium tuberculosis KZN 1435 succinate dehydrogenase membrane anchor subunit YP_003030174.1 300774 R 478434 CDS YP_003030175.1 253797174 8162424 complement(301675..301968) 1 NC_012943.1 hypothetical protein 301968 8162424 TBMG_00252 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030175.1 301675 R 478434 CDS YP_003030176.1 253797175 8162425 complement(302113..302592) 1 NC_012943.1 heat shock protein hsp 302592 8162425 TBMG_00253 Mycobacterium tuberculosis KZN 1435 heat shock protein hsp YP_003030176.1 302113 R 478434 CDS YP_003030177.1 253797176 8162426 302806..305367 1 NC_012943.1 nitrite reductase [NAD(P)H] large subunit nirB 305367 8162426 TBMG_00254 Mycobacterium tuberculosis KZN 1435 nitrite reductase [NAD(P)H] large subunit nirB YP_003030177.1 302806 D 478434 CDS YP_003030178.1 253797177 8162427 305393..305749 1 NC_012943.1 nitrite reductase [NAD(P)H] small subunit nirD 305749 8162427 TBMG_00255 Mycobacterium tuberculosis KZN 1435 nitrite reductase [NAD(P)H] small subunit nirD YP_003030178.1 305393 D 478434 CDS YP_003030179.1 253797178 8162428 complement(305765..306289) 1 NC_012943.1 bifunctional cobalamin biosynthesis protein cobU 306289 8162428 TBMG_00256 Mycobacterium tuberculosis KZN 1435 bifunctional cobalamin biosynthesis protein cobU YP_003030179.1 305765 R 478434 CDS YP_003030180.1 253797179 8162429 complement(306314..307798) 1 NC_012943.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 307798 8162429 TBMG_00257 Mycobacterium tuberculosis KZN 1435 cobyric acid synthase YP_003030180.1 306314 R 478434 CDS YP_003030181.1 253797180 8162430 complement(307817..309487) 1 NC_012943.1 PPE family protein 309487 8162430 TBMG_00258 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030181.1 307817 R 478434 CDS YP_003030182.1 253797181 8162431 309639..310013 1 NC_012943.1 hypothetical protein 310013 8162431 TBMG_03982 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030182.1 309639 D 478434 CDS YP_003030183.1 253797182 8162432 complement(309877..310209) 1 NC_012943.1 hypothetical protein 310209 8162432 TBMG_00259 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030183.1 309877 R 478434 CDS YP_003030184.1 253797183 8162433 complement(310234..310689) 1 NC_012943.1 hypothetical protein 310689 8162433 TBMG_00260 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030184.1 310234 R 478434 CDS YP_003030185.1 253797184 8162434 complement(310714..311457) 1 NC_012943.1 hypothetical protein 311457 8162434 TBMG_00261 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030185.1 310714 R 478434 CDS YP_003030186.1 253797185 8162435 complement(311454..312599) 1 NC_012943.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; bifunctional uroporphyrinogen-III synthetase/response regulator domain protein 312599 8162435 TBMG_00262 Mycobacterium tuberculosis KZN 1435 bifunctional uroporphyrinogen-III synthetase/response regulator domain protein YP_003030186.1 311454 R 478434 CDS YP_003030187.1 253797186 8162436 complement(312699..314108) 1 NC_012943.1 membrane nitrite extrusion protein narK3 314108 8162436 TBMG_00263 Mycobacterium tuberculosis KZN 1435 membrane nitrite extrusion protein narK3 YP_003030187.1 312699 R 478434 CDS YP_003030188.1 253797187 8162437 complement(314249..314794) 1 NC_012943.1 aminoglycoside 2-N-acetyltransferase aac 314794 8162437 TBMG_00264 Mycobacterium tuberculosis KZN 1435 aminoglycoside 2-N-acetyltransferase aac YP_003030188.1 314249 R 478434 CDS YP_003030189.1 253797188 8162438 complement(314804..315706) 1 NC_012943.1 hypothetical protein 315706 8162438 TBMG_00265 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030189.1 314804 R 478434 CDS YP_003030190.1 253797189 8162439 complement(315723..316376) 1 NC_012943.1 hypothetical protein 316376 8162439 TBMG_00266 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030190.1 315723 R 478434 CDS YP_003030191.1 253797190 8162440 complement(316451..317443) 1 NC_012943.1 periplasmic iron-transport lipoprotein 317443 8162440 TBMG_00267 Mycobacterium tuberculosis KZN 1435 periplasmic iron-transport lipoprotein YP_003030191.1 316451 R 478434 CDS YP_003030192.1 253797191 8162441 complement(317465..321094) 1 NC_012943.1 5-oxoprolinase 321094 8162441 TBMG_00268 Mycobacterium tuberculosis KZN 1435 5-oxoprolinase YP_003030192.1 317465 R 478434 CDS YP_003030193.1 253797192 8162442 321271..322662 1 NC_012943.1 membrane nitrite extrusion protein narU 322662 8162442 TBMG_00269 Mycobacterium tuberculosis KZN 1435 membrane nitrite extrusion protein narU YP_003030193.1 321271 D 478434 CDS YP_003030194.1 253797193 8162443 complement(322704..323213) 1 NC_012943.1 hypothetical protein 323213 8162443 TBMG_00270 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030194.1 322704 R 478434 CDS YP_003030195.1 253797194 8162444 complement(323278..324471) 1 NC_012943.1 hypothetical protein 324471 8162444 TBMG_00271 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030195.1 323278 R 478434 CDS YP_003030196.1 253797195 8162445 324507..326189 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 326189 8162445 TBMG_00272 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030196.1 324507 D 478434 CDS YP_003030197.1 253797196 8162446 complement(326206..328401) 1 NC_012943.1 acyl-CoA dehydrogenase 328401 8162446 TBMG_00273 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030197.1 326206 R 478434 CDS YP_003030198.1 253797197 8162447 complement(328515..329648) 1 NC_012943.1 hypothetical protein 329648 8162447 TBMG_00274 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030198.1 328515 R 478434 CDS YP_003030199.1 253797198 8162448 complement(329645..330265) 1 NC_012943.1 transcriptional regulator 330265 8162448 TBMG_00275 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030199.1 329645 R 478434 CDS YP_003030200.1 253797199 8162449 330320..330943 1 NC_012943.1 hypothetical protein 330943 8162449 TBMG_00276 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030200.1 330320 D 478434 CDS YP_003030201.1 253797200 8162450 complement(330873..331598) 1 NC_012943.1 TetR family transcriptional regulator 331598 8162450 TBMG_00277 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030201.1 330873 R 478434 CDS YP_003030202.1 253797201 8162451 331688..332608 1 NC_012943.1 hypothetical protein 332608 8162451 TBMG_00278 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030202.1 331688 D 478434 CDS YP_003030203.1 253797202 8162452 complement(332648..333076) 1 NC_012943.1 toxin 333076 8162452 TBMG_00279 Mycobacterium tuberculosis KZN 1435 toxin YP_003030203.1 332648 R 478434 CDS YP_003030204.1 253797203 8162453 complement(333100..333273) 1 NC_012943.1 antitoxin 333273 8162453 TBMG_00280 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030204.1 333100 R 478434 CDS YP_003030205.1 253797204 8162454 complement(333377..336280) 1 NC_012943.1 PE-PGRS family protein 336280 8162454 TBMG_03983 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030205.1 333377 R 478434 CDS YP_003030206.1 253797205 8162455 complement(336439..339198) 1 NC_012943.1 hypothetical protein 339198 8162455 TBMG_00283 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030206.1 336439 R 478434 CDS YP_003030207.1 253797206 8162456 complement(339427..341961) 1 NC_012943.1 PE-PGRS family protein 341961 8162456 TBMG_00284 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030207.1 339427 R 478434 CDS YP_003030208.1 253797207 8162457 342231..343841 1 NC_012943.1 PPE family protein 343841 8162457 TBMG_00285 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030208.1 342231 D 478434 CDS YP_003030209.1 253797208 8162458 343865..344773 1 NC_012943.1 hypothetical protein 344773 8162458 TBMG_00286 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030209.1 343865 D 478434 CDS YP_003030210.1 253797209 8162459 344997..346892 1 NC_012943.1 hypothetical protein 346892 8162459 TBMG_00287 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030210.1 344997 D 478434 CDS YP_003030211.1 253797210 8162460 346889..348505 1 NC_012943.1 hypothetical protein 348505 8162460 TBMG_00288 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030211.1 346889 D 478434 CDS YP_003030212.1 253797211 8162461 348502..352494 1 NC_012943.1 hypothetical protein 352494 8162461 TBMG_00289 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030212.1 348502 D 478434 CDS YP_003030213.1 253797212 8162462 352491..352799 1 NC_012943.1 PE family protein 352799 8162462 TBMG_00290 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003030213.1 352491 D 478434 CDS YP_003030214.1 253797213 8162463 352802..354343 1 NC_012943.1 PPE family protein 354343 8162463 TBMG_00291 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030214.1 352802 D 478434 CDS YP_003030215.1 253797214 8162464 354392..354685 1 NC_012943.1 esat-6 like protein esxG 354685 8162464 TBMG_00292 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxG YP_003030215.1 354392 D 478434 CDS YP_003030216.1 253797215 8162465 354715..355005 1 NC_012943.1 low molecular weight protein antigen 7 esxH 355005 8162465 TBMG_00293 Mycobacterium tuberculosis KZN 1435 low molecular weight protein antigen 7 esxH YP_003030216.1 354715 D 478434 CDS YP_003030217.1 253797216 8162466 355016..355903 1 NC_012943.1 hypothetical protein 355903 8162466 TBMG_00294 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030217.1 355016 D 478434 CDS YP_003030218.1 253797217 8162467 355950..357368 1 NC_012943.1 hypothetical protein 357368 8162467 TBMG_00295 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030218.1 355950 D 478434 CDS YP_003030219.1 253797218 8162468 357365..358750 1 NC_012943.1 membrane-anchored mycosin mycP3 358750 8162468 TBMG_00296 Mycobacterium tuberculosis KZN 1435 membrane-anchored mycosin mycP3 YP_003030219.1 357365 D 478434 CDS YP_003030220.1 253797219 8162469 358747..359742 1 NC_012943.1 hypothetical protein 359742 8162469 TBMG_00297 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030220.1 358747 D 478434 CDS YP_003030221.1 253797220 8162470 complement(359729..360931) 1 NC_012943.1 hypothetical protein 360931 8162470 TBMG_00298 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030221.1 359729 R 478434 CDS YP_003030222.1 253797221 8162471 361038..361823 1 NC_012943.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 361823 8162471 TBMG_00299 Mycobacterium tuberculosis KZN 1435 trans-aconitate 2-methyltransferase YP_003030222.1 361038 D 478434 CDS YP_003030223.1 253797222 8162472 complement(361812..362615) 1 NC_012943.1 hypothetical protein 362615 8162472 TBMG_00300 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030223.1 361812 R 478434 CDS YP_003030224.1 253797223 8162473 complement(362625..364031) 1 NC_012943.1 sulfatase 364031 8162473 TBMG_00301 Mycobacterium tuberculosis KZN 1435 sulfatase YP_003030224.1 362625 R 478434 CDS YP_003030225.1 253797224 8162474 364201..366039 1 NC_012943.1 hypothetical protein 366039 8162474 TBMG_00302 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030225.1 364201 D 478434 CDS YP_003030226.1 253797225 8162475 366109..366336 1 NC_012943.1 hypothetical protein 366336 8162475 TBMG_00303 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030226.1 366109 D 478434 CDS YP_003030227.1 253797226 8162476 366333..366635 1 NC_012943.1 hypothetical protein 366635 8162476 TBMG_00304 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030227.1 366333 D 478434 CDS YP_003030228.1 253797227 8162477 366683..366904 1 NC_012943.1 antitoxin 366904 8162477 TBMG_00305 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030228.1 366683 D 478434 CDS YP_003030229.1 253797228 8162478 366901..367326 1 NC_012943.1 toxin 367326 8162478 TBMG_00306 Mycobacterium tuberculosis KZN 1435 toxin YP_003030229.1 366901 D 478434 CDS YP_003030230.1 253797229 8162479 367462..368094 1 NC_012943.1 TetR family transcriptional regulator 368094 8162479 TBMG_00307 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030230.1 367462 D 478434 CDS YP_003030231.1 253797230 8162480 368091..368999 1 NC_012943.1 dehydrogenase/reductase 368999 8162480 TBMG_00308 Mycobacterium tuberculosis KZN 1435 dehydrogenase/reductase YP_003030231.1 368091 D 478434 CDS YP_003030232.1 253797231 8162481 complement(369007..378597) 1 NC_012943.1 PPE family protein 378597 8162481 TBMG_00309 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030232.1 369007 R 478434 CDS YP_003030233.1 253797232 8162482 378800..379471 1 NC_012943.1 oxidoreductase 379471 8162482 TBMG_00310 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030233.1 378800 D 478434 CDS YP_003030234.1 253797233 8162483 complement(379459..379941) 1 NC_012943.1 hypothetical protein 379941 8162483 TBMG_00311 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030234.1 379459 R 478434 CDS YP_003030235.1 253797234 8162484 379999..380715 1 NC_012943.1 hypothetical protein 380715 8162484 TBMG_00312 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030235.1 379999 D 478434 CDS YP_003030236.1 253797235 8162485 380817..381473 1 NC_012943.1 hypothetical protein 381473 8162485 TBMG_00313 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030236.1 380817 D 478434 CDS YP_003030237.1 253797236 8162486 complement(381543..382034) 1 NC_012943.1 hypothetical protein 382034 8162486 TBMG_00314 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030237.1 381543 R 478434 CDS YP_003030238.1 253797237 8162487 382058..383287 1 NC_012943.1 hypothetical protein 383287 8162487 TBMG_00315 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030238.1 382058 D 478434 CDS YP_003030239.1 253797238 8162488 383442..385304 1 NC_012943.1 hypothetical protein 385304 8162488 TBMG_00316 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030239.1 383442 D 478434 CDS YP_003030240.1 253797239 8162489 385376..385762 1 NC_012943.1 hypothetical protein 385762 8162489 TBMG_00317 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030240.1 385376 D 478434 CDS YP_003030241.1 253797240 8162490 complement(385765..386427) 1 NC_012943.1 hypothetical protein 386427 8162490 TBMG_00318 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030241.1 385765 R 478434 CDS YP_003030242.1 253797241 8162491 386518..387372 1 NC_012943.1 beta-1,3-glucanase precursor 387372 8162491 TBMG_00319 Mycobacterium tuberculosis KZN 1435 beta-1,3-glucanase precursor YP_003030242.1 386518 D 478434 CDS YP_003030243.1 253797242 8162492 387421..388035 1 NC_012943.1 muconolactone isomerase 388035 8162492 TBMG_00320 Mycobacterium tuberculosis KZN 1435 muconolactone isomerase YP_003030243.1 387421 D 478434 CDS YP_003030244.1 253797243 8162333 complement(388059..388829) 1 NC_012943.1 glycerophosphoryl diester phosphodiesterase glpQ2 388829 8162333 TBMG_00321 Mycobacterium tuberculosis KZN 1435 glycerophosphoryl diester phosphodiesterase glpQ2 YP_003030244.1 388059 R 478434 CDS YP_003030245.1 253797244 8162496 complement(389191..389985) 1 NC_012943.1 hypothetical protein 389985 8162496 TBMG_00322 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030245.1 389191 R 478434 CDS YP_003030246.1 253797245 8162497 390034..390702 1 NC_012943.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 390702 8162497 TBMG_00323 Mycobacterium tuberculosis KZN 1435 pyrrolidone-carboxylate peptidase YP_003030246.1 390034 D 478434 CDS YP_003030247.1 253797246 8162498 390774..391436 1 NC_012943.1 hypothetical protein 391436 8162498 TBMG_00324 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030247.1 390774 D 478434 CDS YP_003030248.1 253797247 8162499 391468..392040 1 NC_012943.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 392040 dcd 8162499 dcd Mycobacterium tuberculosis KZN 1435 deoxycytidine triphosphate deaminase YP_003030248.1 391468 D 478434 CDS YP_003030249.1 253797248 8162500 392146..393477 1 NC_012943.1 UDP-glucose 6-dehydrogenase udgA 393477 8162500 TBMG_00326 Mycobacterium tuberculosis KZN 1435 UDP-glucose 6-dehydrogenase udgA YP_003030249.1 392146 D 478434 CDS YP_003030250.1 253797249 8162501 complement(393466..394137) 1 NC_012943.1 hypothetical protein 394137 8162501 TBMG_00327 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030250.1 393466 R 478434 CDS YP_003030251.1 253797250 8162502 394238..394918 1 NC_012943.1 transcriptional regulator, arsR-family 394918 8162502 TBMG_00328 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, arsR-family YP_003030251.1 394238 D 478434 CDS YP_003030252.1 253797251 8162503 394925..395149 1 NC_012943.1 hypothetical protein 395149 8162503 TBMG_00329 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030252.1 394925 D 478434 CDS YP_003030253.1 253797252 8162504 395159..395614 1 NC_012943.1 hypothetical protein 395614 8162504 TBMG_00330 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030253.1 395159 D 478434 CDS YP_003030254.1 253797253 8162505 complement(395582..396931) 1 NC_012943.1 cytochrome P450 135A1 cyp135A1 396931 8162505 TBMG_00331 Mycobacterium tuberculosis KZN 1435 cytochrome P450 135A1 cyp135A1 YP_003030254.1 395582 R 478434 CDS YP_003030255.1 253797254 8162506 396997..397599 1 NC_012943.1 TetR family transcriptional regulator 397599 8162506 TBMG_00332 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030255.1 396997 D 478434 CDS YP_003030256.1 253797255 8162507 complement(397580..398206) 1 NC_012943.1 hypothetical protein 398206 8162507 TBMG_00333 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030256.1 397580 R 478434 CDS YP_003030257.1 253797256 8162508 complement(398233..398973) 1 NC_012943.1 hypothetical protein 398973 8162508 TBMG_00334 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030257.1 398233 R 478434 CDS YP_003030258.1 253797257 8162509 399087..400253 1 NC_012943.1 dehydrogenase/reductase 400253 8162509 TBMG_00335 Mycobacterium tuberculosis KZN 1435 dehydrogenase/reductase YP_003030258.1 399087 D 478434 CDS YP_003030259.1 253797258 8162510 400328..401113 1 NC_012943.1 hypothetical protein 401113 8162510 TBMG_00336 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030259.1 400328 D 478434 CDS YP_003030260.1 253797259 8162511 401140..401514 1 NC_012943.1 hypothetical protein 401514 8162511 TBMG_00337 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030260.1 401140 D 478434 CDS YP_003030261.1 253797260 8162512 401544..402410 1 NC_012943.1 alpha-D-glucose-1-phosphate thymidylyltransferase 402410 8162512 TBMG_00338 Mycobacterium tuberculosis KZN 1435 alpha-D-glucose-1-phosphate thymidylyltransferase YP_003030261.1 401544 D 478434 CDS YP_003030262.1 253797261 8162513 complement(402421..402936) 1 NC_012943.1 PE family protein 402936 8162513 TBMG_00339 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003030262.1 402421 R 478434 CDS YP_003030263.1 253797262 8162514 403054..404589 1 NC_012943.1 hypothetical protein 404589 8162514 TBMG_00340 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030263.1 403054 D 478434 CDS YP_003030264.1 253797263 8162515 complement(404759..406048) 1 NC_012943.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 406048 8162515 TBMG_00341 Mycobacterium tuberculosis KZN 1435 aminotransferase YP_003030264.1 404759 R 478434 CDS YP_003030265.1 253797264 8162516 complement(406079..408727) 1 NC_012943.1 iron-sulfur-binding reductase 408727 8162516 TBMG_00342 Mycobacterium tuberculosis KZN 1435 iron-sulfur-binding reductase YP_003030265.1 406079 R 478434 CDS YP_003030266.1 253797265 8162517 complement(408836..411334) 1 NC_012943.1 transcriptional regulator 411334 8162517 TBMG_00343 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030266.1 408836 R 478434 CDS YP_003030267.1 253797266 8162518 411520..412059 1 NC_012943.1 hypothetical protein 412059 8162518 TBMG_00344 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030267.1 411520 D 478434 CDS YP_003030268.1 253797267 8162519 412242..413687 1 NC_012943.1 isoniazid inductible protein iniB 413687 8162519 TBMG_00345 Mycobacterium tuberculosis KZN 1435 isoniazid inductible protein iniB YP_003030268.1 412242 D 478434 CDS YP_003030269.1 253797268 8162520 413724..415646 1 NC_012943.1 isoniazid inductible protein iniA 415646 8162520 TBMG_00346 Mycobacterium tuberculosis KZN 1435 isoniazid inductible protein iniA YP_003030269.1 413724 D 478434 CDS YP_003030270.1 253797269 8162521 415643..417124 1 NC_012943.1 isoniazid inductible protein iniC 417124 8162521 TBMG_00347 Mycobacterium tuberculosis KZN 1435 isoniazid inductible protein iniC YP_003030270.1 415643 D 478434 CDS YP_003030271.1 253797270 8162522 complement(417267..417827) 1 NC_012943.1 hypothetical protein 417827 8162522 TBMG_00348 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030271.1 417267 R 478434 CDS YP_003030272.1 253797271 8162523 417930..418346 1 NC_012943.1 hypothetical protein 418346 8162523 TBMG_00349 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030272.1 417930 D 478434 CDS YP_003030273.1 253797272 8162524 complement(418388..419851) 1 NC_012943.1 L-asparagine permease ansP2 419851 8162524 TBMG_00350 Mycobacterium tuberculosis KZN 1435 L-asparagine permease ansP2 YP_003030273.1 418388 R 478434 CDS YP_003030274.1 253797273 8162525 420190..421176 1 NC_012943.1 hypothetical protein 421176 8162525 TBMG_00351 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030274.1 420190 D 478434 CDS YP_003030275.1 253797274 8162526 421179..421832 1 NC_012943.1 transcriptional regulator 421832 8162526 TBMG_00352 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030275.1 421179 D 478434 CDS YP_003030276.1 253797275 8162527 421835..422494 1 NC_012943.1 hypothetical protein 422494 8162527 TBMG_00353 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030276.1 421835 D 478434 CDS YP_003030277.1 253797276 8162528 422721..424598 1 NC_012943.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 424598 dnaK 8162528 dnaK Mycobacterium tuberculosis KZN 1435 molecular chaperone DnaK YP_003030277.1 422721 D 478434 CDS YP_003030278.1 253797277 8162529 424595..425302 1 NC_012943.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 425302 8162529 TBMG_00355 Mycobacterium tuberculosis KZN 1435 heat shock protein GrpE YP_003030278.1 424595 D 478434 CDS YP_003030279.1 253797278 8162530 425338..426525 1 NC_012943.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 426525 8162530 TBMG_00356 Mycobacterium tuberculosis KZN 1435 molecular chaperone DnaJ YP_003030279.1 425338 D 478434 CDS YP_003030280.1 253797279 8162531 426525..426905 1 NC_012943.1 merR-family heat shock protein transcriptional repressor hspR 426905 8162531 TBMG_00357 Mycobacterium tuberculosis KZN 1435 merR-family heat shock protein transcriptional repressor hspR YP_003030280.1 426525 D 478434 CDS YP_003030281.1 253797280 8162532 complement(427081..427632) 1 NC_012943.1 PPE family protein 427632 8162532 TBMG_00358 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030281.1 427081 R 478434 CDS YP_003030282.1 253797281 8162533 complement(427715..437542) 1 NC_012943.1 PPE family protein 437542 8162533 TBMG_00359 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030282.1 427715 R 478434 CDS YP_003030283.1 253797282 8162534 complement(437693..438337) 1 NC_012943.1 hypothetical protein 438337 8162534 TBMG_00360 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030283.1 437693 R 478434 CDS YP_003030284.1 253797283 8162535 complement(438334..439632) 1 NC_012943.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 439632 8162535 TBMG_00361 Mycobacterium tuberculosis KZN 1435 adenylosuccinate synthetase YP_003030284.1 438334 R 478434 CDS YP_003030285.1 253797284 8162536 439723..440370 1 NC_012943.1 hypothetical protein 440370 8162536 TBMG_00362 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030285.1 439723 D 478434 CDS YP_003030286.1 253797285 8162537 440381..441160 1 NC_012943.1 hypothetical protein 441160 8162537 TBMG_00363 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030286.1 440381 D 478434 CDS YP_003030287.1 253797286 8162538 complement(441165..441602) 1 NC_012943.1 hypothetical protein 441602 8162538 TBMG_00364 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030287.1 441165 R 478434 CDS YP_003030288.1 253797287 8162539 441685..442512 1 NC_012943.1 hypothetical protein 442512 8162539 TBMG_00365 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030288.1 441685 D 478434 CDS YP_003030289.1 253797288 8162540 442734..444116 1 NC_012943.1 hypothetical protein 444116 8162540 TBMG_00366 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030289.1 442734 D 478434 CDS YP_003030290.1 253797289 8162541 complement(444128..445162) 1 NC_012943.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 445162 8162541 TBMG_00367 Mycobacterium tuberculosis KZN 1435 fructose-bisphosphate aldolase YP_003030290.1 444128 R 478434 CDS YP_003030291.1 253797290 8162542 445258..445941 1 NC_012943.1 hypothetical protein 445941 8162542 TBMG_00368 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030291.1 445258 D 478434 CDS YP_003030292.1 253797291 8162543 complement(445930..447060) 1 NC_012943.1 hypothetical protein 447060 8162543 TBMG_00369 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030292.1 445930 R 478434 CDS YP_003030293.1 253797292 8162544 complement(447085..447678) 1 NC_012943.1 hypothetical protein 447678 8162544 TBMG_00370 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030293.1 447085 R 478434 CDS YP_003030294.1 253797293 8162545 complement(447707..448096) 1 NC_012943.1 hypothetical protein 448096 8162545 TBMG_00371 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030294.1 447707 R 478434 CDS YP_003030295.1 253797294 8162546 complement(448177..449388) 1 NC_012943.1 hypothetical protein 449388 8162546 TBMG_00372 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030295.1 448177 R 478434 CDS YP_003030296.1 253797295 8162547 complement(449394..449996) 1 NC_012943.1 membrane oxidoreductase 449996 8162547 TBMG_00373 Mycobacterium tuberculosis KZN 1435 membrane oxidoreductase YP_003030296.1 449394 R 478434 CDS YP_003030297.1 253797296 8162548 complement(450010..450906) 1 NC_012943.1 oxidoreductase 450906 8162548 TBMG_00374 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030297.1 450010 R 478434 CDS YP_003030298.1 253797297 8162549 complement(450903..451496) 1 NC_012943.1 hypothetical protein 451496 8162549 TBMG_00375 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030298.1 450903 R 478434 CDS YP_003030299.1 253797298 8162550 complement(451493..452248) 1 NC_012943.1 hypothetical protein 452248 8162550 TBMG_00376 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030299.1 451493 R 478434 CDS YP_003030300.1 253797299 8162551 complement(452267..454666) 1 NC_012943.1 carbon monoxyde dehydrogenase large subunit 454666 8162551 TBMG_00377 Mycobacterium tuberculosis KZN 1435 carbon monoxyde dehydrogenase large subunit YP_003030300.1 452267 R 478434 CDS YP_003030301.1 253797300 8162552 complement(454663..455142) 1 NC_012943.1 carbon monoxyde dehydrogenase small subunit 455142 8162552 TBMG_00378 Mycobacterium tuberculosis KZN 1435 carbon monoxyde dehydrogenase small subunit YP_003030301.1 454663 R 478434 CDS YP_003030302.1 253797301 8162553 complement(455157..456059) 1 NC_012943.1 carbon monoxyde dehydrogenase subunit medium 456059 8162553 TBMG_00379 Mycobacterium tuberculosis KZN 1435 carbon monoxyde dehydrogenase subunit medium YP_003030302.1 455157 R 478434 CDS YP_003030303.1 253797302 8162554 456234..456449 1 NC_012943.1 preprotein translocase subunit secE2 456449 8162554 TBMG_00380 Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit secE2 YP_003030303.1 456234 D 478434 CDS YP_003030304.1 253797303 8162555 complement(456525..457187) 1 NC_012943.1 RNA methyltransferase 457187 8162555 TBMG_00381 Mycobacterium tuberculosis KZN 1435 RNA methyltransferase YP_003030304.1 456525 R 478434 CDS YP_003030305.1 253797304 8162556 complement(457172..458080) 1 NC_012943.1 hypothetical protein 458080 8162556 TBMG_00382 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030305.1 457172 R 478434 CDS YP_003030306.1 253797305 8162557 complement(458098..458637) 1 NC_012943.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 458637 pyrE 8162557 pyrE Mycobacterium tuberculosis KZN 1435 orotate phosphoribosyltransferase YP_003030306.1 458098 R 478434 CDS YP_003030307.1 253797306 8162558 complement(458718..459572) 1 NC_012943.1 hypothetical protein 459572 8162558 TBMG_00384 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030307.1 458718 R 478434 CDS YP_003030308.1 253797307 8162559 complement(459713..462259) 1 NC_012943.1 endopeptidase subunit ATP binding protein B clpB 462259 8162559 TBMG_00385 Mycobacterium tuberculosis KZN 1435 endopeptidase subunit ATP binding protein B clpB YP_003030308.1 459713 R 478434 CDS YP_003030309.1 253797308 8162560 462287..463564 1 NC_012943.1 monooxygenase 463564 8162560 TBMG_00386 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003030309.1 462287 D 478434 CDS YP_003030310.1 253797309 8162561 463668..466925 1 NC_012943.1 transcriptional regulator, luxR/uhpA-family 466925 8162561 TBMG_00387 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, luxR/uhpA-family YP_003030310.1 463668 D 478434 CDS YP_003030311.1 253797310 8162562 complement(466929..468260) 1 NC_012943.1 PPE family protein 468260 8162562 TBMG_00388 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030311.1 466929 R 478434 CDS YP_003030312.1 253797311 8162563 468594..469853 1 NC_012943.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 469853 purT 8162563 purT Mycobacterium tuberculosis KZN 1435 phosphoribosylglycinamide formyltransferase 2 YP_003030312.1 468594 D 478434 CDS YP_003030313.1 253797312 8162564 469850..470272 1 NC_012943.1 hypothetical protein 470272 8162564 TBMG_00390 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030313.1 469850 D 478434 CDS YP_003030314.1 253797313 8162565 470269..471489 1 NC_012943.1 O-succinylhomoserine sulfhydrylase 471489 8162565 TBMG_00391 Mycobacterium tuberculosis KZN 1435 O-succinylhomoserine sulfhydrylase YP_003030314.1 470269 D 478434 CDS YP_003030315.1 253797314 8162566 complement(471486..472898) 1 NC_012943.1 membrane NADH dehydrogenase ndhA 472898 8162566 TBMG_00392 Mycobacterium tuberculosis KZN 1435 membrane NADH dehydrogenase ndhA YP_003030315.1 471486 R 478434 CDS YP_003030316.1 253797315 8162567 473040..474365 1 NC_012943.1 hypothetical protein 474365 8162567 TBMG_00393 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030316.1 473040 D 478434 CDS YP_003030317.1 253797316 8162568 complement(474381..475100) 1 NC_012943.1 hypothetical protein 475100 8162568 TBMG_00394 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030317.1 474381 R 478434 CDS YP_003030318.1 253797317 8162569 475199..475603 1 NC_012943.1 hypothetical protein 475603 8162569 TBMG_00395 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030318.1 475199 D 478434 CDS YP_003030319.1 253797318 8162570 475585..476001 1 NC_012943.1 hypothetical protein 476001 8162570 TBMG_00396 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030319.1 475585 D 478434 CDS YP_003030320.1 253797319 8162571 476075..476443 1 NC_012943.1 hypothetical protein 476443 8162571 TBMG_00397 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030320.1 476075 D 478434 CDS YP_003030321.1 253797320 8162572 476653..476901 1 NC_012943.1 hypothetical protein 476901 8162572 TBMG_00398 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030321.1 476653 D 478434 CDS YP_003030322.1 253797321 8162573 complement(476938..477579) 1 NC_012943.1 hypothetical protein 477579 8162573 TBMG_00399 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030322.1 476938 R 478434 CDS YP_003030323.1 253797322 8162574 complement(477586..478815) 1 NC_012943.1 hypothetical protein 478815 8162574 TBMG_00400 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030323.1 477586 R 478434 CDS YP_003030324.1 253797323 8162575 complement(478825..480012) 1 NC_012943.1 acyl-CoA dehydrogenase 480012 8162575 TBMG_00401 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030324.1 478825 R 478434 CDS YP_003030325.1 253797324 8162576 480048..480419 1 NC_012943.1 hypothetical protein 480419 8162576 TBMG_00402 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030325.1 480048 D 478434 CDS YP_003030326.1 253797325 8162577 complement(480614..483490) 1 NC_012943.1 transmembrane transporter mmpL1 483490 8162577 TBMG_00403 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL1 YP_003030326.1 480614 R 478434 CDS YP_003030327.1 253797326 8162578 complement(483487..483915) 1 NC_012943.1 hypothetical protein 483915 8162578 TBMG_00404 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030327.1 483487 R 478434 CDS YP_003030328.1 253797327 8162579 484236..485993 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 485993 8162579 TBMG_00405 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030328.1 484236 D 478434 CDS YP_003030329.1 253797328 8162580 485990..490198 1 NC_012943.1 membrane bound polyketide synthase pks6 490198 8162580 TBMG_00406 Mycobacterium tuberculosis KZN 1435 membrane bound polyketide synthase pks6 YP_003030329.1 485990 D 478434 CDS YP_003030330.1 253797329 8164241 complement(490146..490964) 1 NC_012943.1 beta lactamase like protein 490964 8164241 TBMG_00407 Mycobacterium tuberculosis KZN 1435 beta lactamase like protein YP_003030330.1 490146 R 478434 CDS YP_003030331.1 253797330 8164242 491042..492052 1 NC_012943.1 F420-dependent glucose-6-phosphate dehydrogenase 492052 8164242 TBMG_00408 Mycobacterium tuberculosis KZN 1435 F420-dependent glucose-6-phosphate dehydrogenase YP_003030331.1 491042 D 478434 CDS YP_003030332.1 253797331 8164243 492045..494117 1 NC_012943.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 494117 8164243 TBMG_00409 Mycobacterium tuberculosis KZN 1435 phosphate acetyltransferase YP_003030332.1 492045 D 478434 CDS YP_003030333.1 253797332 8164244 494110..495267 1 NC_012943.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 495267 8164244 TBMG_00410 Mycobacterium tuberculosis KZN 1435 acetate kinase YP_003030333.1 494110 D 478434 CDS YP_003030334.1 253797333 8164245 complement(495321..497573) 1 NC_012943.1 serine/threonine-protein kinase pknG 497573 8164245 TBMG_00411 Mycobacterium tuberculosis KZN 1435 serine/threonine-protein kinase pknG YP_003030334.1 495321 R 478434 CDS YP_003030335.1 253797334 8164246 complement(497573..498559) 1 NC_012943.1 glutamine-binding lipoprotein glnH 498559 8164246 TBMG_00412 Mycobacterium tuberculosis KZN 1435 glutamine-binding lipoprotein glnH YP_003030335.1 497573 R 478434 CDS YP_003030336.1 253797335 8164247 complement(498559..499878) 1 NC_012943.1 hypothetical protein 499878 8164247 TBMG_00413 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030336.1 498559 R 478434 CDS YP_003030337.1 253797336 8164248 499972..500625 1 NC_012943.1 mutator protein mutT3 500625 8164248 TBMG_00414 Mycobacterium tuberculosis KZN 1435 mutator protein mutT3 YP_003030337.1 499972 D 478434 CDS YP_003030338.1 253797337 8164249 complement(500609..501277) 1 NC_012943.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 501277 thiE 8164249 thiE Mycobacterium tuberculosis KZN 1435 thiamine-phosphate pyrophosphorylase YP_003030338.1 500609 R 478434 CDS YP_003030339.1 253797338 8164250 501407..502429 1 NC_012943.1 thiamine biosynthesis oxidoreductase thiO 502429 8164250 TBMG_00416 Mycobacterium tuberculosis KZN 1435 thiamine biosynthesis oxidoreductase thiO YP_003030339.1 501407 D 478434 CDS YP_003030340.1 253797339 8164251 502426..502632 1 NC_012943.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 502632 8164251 TBMG_00417 Mycobacterium tuberculosis KZN 1435 sulfur carrier protein ThiS YP_003030340.1 502426 D 478434 CDS YP_003030341.1 253797340 8164252 502625..503383 1 NC_012943.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 503383 thiG 8164252 thiG Mycobacterium tuberculosis KZN 1435 thiazole synthase YP_003030341.1 502625 D 478434 CDS YP_003030342.1 253797341 8164253 503405..503557 1 NC_012943.1 hypothetical protein 503557 8164253 TBMG_03984 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030342.1 503405 D 478434 CDS YP_003030343.1 253797342 8164254 503755..505257 1 NC_012943.1 lipoprotein aminopeptidase lpqL 505257 8164254 TBMG_00419 Mycobacterium tuberculosis KZN 1435 lipoprotein aminopeptidase lpqL YP_003030343.1 503755 D 478434 CDS YP_003030344.1 253797343 8164255 505345..506841 1 NC_012943.1 lipoprotein peptidase lpqM 506841 8164255 TBMG_00420 Mycobacterium tuberculosis KZN 1435 lipoprotein peptidase lpqM YP_003030344.1 505345 D 478434 CDS YP_003030345.1 253797344 8164256 complement(506820..507230) 1 NC_012943.1 hypothetical protein 507230 8164256 TBMG_00421 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030345.1 506820 R 478434 CDS YP_003030346.1 253797345 8164257 complement(507391..508020) 1 NC_012943.1 hypothetical protein 508020 8164257 TBMG_00422 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030346.1 507391 R 478434 CDS YP_003030347.1 253797346 8164258 complement(508017..508844) 1 NC_012943.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 508844 8164258 TBMG_00423 Mycobacterium tuberculosis KZN 1435 phosphomethylpyrimidine kinase YP_003030347.1 508017 R 478434 CDS YP_003030348.1 253797347 8164259 complement(508841..510484) 1 NC_012943.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 510484 8164259 TBMG_00424 Mycobacterium tuberculosis KZN 1435 thiamine biosynthesis protein ThiC YP_003030348.1 508841 R 478434 CDS YP_003030349.1 253797348 8164260 complement(510636..510914) 1 NC_012943.1 hypothetical protein 510914 8164260 TBMG_00425 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030349.1 510636 R 478434 CDS YP_003030350.1 253797349 8164261 complement(510961..515580) 1 NC_012943.1 metal cation transporting P-type ATPase ctpH 515580 8164261 TBMG_00426 Mycobacterium tuberculosis KZN 1435 metal cation transporting P-type ATPase ctpH YP_003030350.1 510961 R 478434 CDS YP_003030351.1 253797350 8164262 complement(515632..516207) 1 NC_012943.1 hypothetical protein 516207 8164262 TBMG_00427 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030351.1 515632 R 478434 CDS YP_003030352.1 253797351 8164263 complement(516276..517151) 1 NC_012943.1 exodeoxyribonuclease III protein xthA 517151 8164263 TBMG_00428 Mycobacterium tuberculosis KZN 1435 exodeoxyribonuclease III protein xthA YP_003030352.1 516276 R 478434 CDS YP_003030353.1 253797352 8164264 complement(517154..518062) 1 NC_012943.1 hypothetical protein 518062 8164264 TBMG_00429 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030353.1 517154 R 478434 CDS YP_003030354.1 253797353 8164265 complement(518062..518655) 1 NC_012943.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 518655 def 8164265 def Mycobacterium tuberculosis KZN 1435 peptide deformylase YP_003030354.1 518062 R 478434 CDS YP_003030355.1 253797354 8164266 518848..519300 1 NC_012943.1 hypothetical protein 519300 8164266 TBMG_00431 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030355.1 518848 D 478434 CDS YP_003030356.1 253797355 8164267 519332..519826 1 NC_012943.1 tuberculin related peptide 519826 8164267 TBMG_00432 Mycobacterium tuberculosis KZN 1435 tuberculin related peptide YP_003030356.1 519332 D 478434 CDS YP_003030357.1 253797356 8164268 519859..520581 1 NC_012943.1 periplasmic superoxide dismutase [Cu-Zn] sodC 520581 8164268 TBMG_00433 Mycobacterium tuberculosis KZN 1435 periplasmic superoxide dismutase [Cu-Zn] sodC YP_003030357.1 519859 D 478434 CDS YP_003030358.1 253797357 8164269 520583..521713 1 NC_012943.1 ATP-dependent carboxylate-amine ligase; carboxylate-amine ligase 521713 8164269 TBMG_00434 Mycobacterium tuberculosis KZN 1435 carboxylate-amine ligase YP_003030358.1 520583 D 478434 CDS YP_003030359.1 253797358 8164270 521770..522426 1 NC_012943.1 hypothetical protein 522426 8164270 TBMG_00435 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030359.1 521770 D 478434 CDS YP_003030360.1 253797359 8164271 complement(522606..524792) 1 NC_012943.1 ATPase 524792 8164271 TBMG_00436 Mycobacterium tuberculosis KZN 1435 ATPase YP_003030360.1 522606 R 478434 CDS YP_003030361.1 253797360 8164272 complement(524789..525649) 1 NC_012943.1 CDP-diacylglycerol-serine O-phosphatidyltransferase pssA 525649 8164272 TBMG_00437 Mycobacterium tuberculosis KZN 1435 CDP-diacylglycerol-serine O-phosphatidyltransferase pssA YP_003030361.1 524789 R 478434 CDS YP_003030362.1 253797361 8164273 complement(525646..526341) 1 NC_012943.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 526341 8164273 TBMG_00438 Mycobacterium tuberculosis KZN 1435 phosphatidylserine decarboxylase YP_003030362.1 525646 R 478434 CDS YP_003030363.1 253797362 8164274 complement(526402..527619) 1 NC_012943.1 molybdopterin biosynthesis protein moeA2 527619 8164274 TBMG_00439 Mycobacterium tuberculosis KZN 1435 molybdopterin biosynthesis protein moeA2 YP_003030363.1 526402 R 478434 CDS YP_003030364.1 253797363 8164275 complement(527638..528573) 1 NC_012943.1 short chain dehydrogenase 528573 8164275 TBMG_00440 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003030364.1 527638 R 478434 CDS YP_003030365.1 253797364 8164276 528867..530489 1 NC_012943.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 530489 groEL 8164276 groEL Mycobacterium tuberculosis KZN 1435 molecular chaperone GroEL YP_003030365.1 528867 D 478434 CDS YP_003030366.1 253797365 8164277 complement(530555..530983) 1 NC_012943.1 hypothetical protein 530983 8164277 TBMG_00442 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030366.1 530555 R 478434 CDS YP_003030367.1 253797366 8164278 complement(531010..532473) 1 NC_012943.1 PPE family protein 532473 8164278 TBMG_00443 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030367.1 531010 R 478434 CDS YP_003030368.1 253797367 8164279 532613..533170 1 NC_012943.1 hypothetical protein 533170 8164279 TBMG_00444 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030368.1 532613 D 478434 CDS YP_003030369.1 253797368 8164280 complement(533350..534048) 1 NC_012943.1 hypothetical protein 534048 8164280 TBMG_00445 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030369.1 533350 R 478434 CDS YP_003030370.1 253797369 8164281 complement(534092..534655) 1 NC_012943.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; RNA polymerase sigma factor SigK 534655 8164281 TBMG_00446 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigK YP_003030370.1 534092 R 478434 CDS YP_003030371.1 253797370 8164282 complement(534704..534892) 1 NC_012943.1 hypothetical protein 534892 8164282 TBMG_03985 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030371.1 534704 R 478434 CDS YP_003030372.1 253797371 8164283 complement(534950..535486) 1 NC_012943.1 hypothetical protein 535486 8164283 TBMG_00447 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030372.1 534950 R 478434 CDS YP_003030373.1 253797372 8164284 complement(535483..536766) 1 NC_012943.1 cyclopropane-fatty-acyl-phospholipid synthase ufaA1 536766 8164284 TBMG_00448 Mycobacterium tuberculosis KZN 1435 cyclopropane-fatty-acyl-phospholipid synthase ufaA1 YP_003030373.1 535483 R 478434 CDS YP_003030374.1 253797373 8164285 complement(536763..537428) 1 NC_012943.1 hypothetical protein 537428 8164285 TBMG_00449 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030374.1 536763 R 478434 CDS YP_003030375.1 253797374 8164286 complement(537488..538807) 1 NC_012943.1 hypothetical protein 538807 8164286 TBMG_00450 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030375.1 537488 R 478434 CDS YP_003030376.1 253797375 8164287 complement(538847..541750) 1 NC_012943.1 transmembrane transporter mmpL4 541750 8164287 TBMG_00451 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL4 YP_003030376.1 538847 R 478434 CDS YP_003030377.1 253797376 8164288 complement(541747..542169) 1 NC_012943.1 hypothetical protein 542169 8164288 TBMG_00452 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030377.1 541747 R 478434 CDS YP_003030378.1 253797377 8164289 542350..543111 1 NC_012943.1 transcriptional regulator 543111 8164289 TBMG_00453 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030378.1 542350 D 478434 CDS YP_003030379.1 253797378 8164290 543433..544989 1 NC_012943.1 PPE family protein 544989 8164290 TBMG_00454 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030379.1 543433 D 478434 CDS YP_003030380.1 253797379 8164291 complement(544995..545549) 1 NC_012943.1 hypothetical protein 545549 8164291 TBMG_00455 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030380.1 544995 R 478434 CDS YP_003030381.1 253797380 8164292 complement(545634..546161) 1 NC_012943.1 hypothetical protein 546161 8164292 TBMG_00456 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030381.1 545634 R 478434 CDS YP_003030382.1 253797381 8164293 complement(546148..547062) 1 NC_012943.1 catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 547062 8164293 TBMG_00457 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003030382.1 546148 R 478434 CDS YP_003030383.1 253797382 8164294 complement(547335..547616) 1 NC_012943.1 toxin 547616 8164294 TBMG_03986 Mycobacterium tuberculosis KZN 1435 toxin YP_003030383.1 547335 R 478434 CDS YP_003030384.1 253797383 8164295 complement(547603..547776) 1 NC_012943.1 antitoxin 547776 8164295 TBMG_03987 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030384.1 547603 R 478434 CDS YP_003030385.1 253797384 8164296 complement(547845..549875) 1 NC_012943.1 peptidase 549875 8164296 TBMG_00459 Mycobacterium tuberculosis KZN 1435 peptidase YP_003030385.1 547845 R 478434 CDS YP_003030386.1 253797385 8164297 549934..551457 1 NC_012943.1 aldehyde dehydrogenase 551457 8164297 TBMG_00460 Mycobacterium tuberculosis KZN 1435 aldehyde dehydrogenase YP_003030386.1 549934 D 478434 CDS YP_003030387.1 253797386 8164298 551457..551948 1 NC_012943.1 hypothetical protein 551948 8164298 TBMG_00461 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030387.1 551457 D 478434 CDS YP_003030388.1 253797387 8164299 551969..552247 1 NC_012943.1 hydrophobic protein 552247 8164299 TBMG_00462 Mycobacterium tuberculosis KZN 1435 hydrophobic protein YP_003030388.1 551969 D 478434 CDS YP_003030389.1 253797388 8164300 552240..552809 1 NC_012943.1 hypothetical protein 552809 8164300 TBMG_00463 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030389.1 552240 D 478434 CDS YP_003030390.1 253797389 8164301 552873..554267 1 NC_012943.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; dihydrolipoamide dehydrogenase 554267 8164301 TBMG_00464 Mycobacterium tuberculosis KZN 1435 dihydrolipoamide dehydrogenase YP_003030390.1 552873 D 478434 CDS YP_003030391.1 253797390 8164302 554275..554568 1 NC_012943.1 hypothetical protein 554568 8164302 TBMG_00465 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030391.1 554275 D 478434 CDS YP_003030392.1 253797391 8164303 complement(554572..555144) 1 NC_012943.1 hypothetical protein 555144 8164303 TBMG_00466 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030392.1 554572 R 478434 CDS YP_003030393.1 253797392 8164304 complement(555141..556565) 1 NC_012943.1 transcriptional regulator 556565 8164304 TBMG_00467 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030393.1 555141 R 478434 CDS YP_003030394.1 253797393 8164305 556717..557511 1 NC_012943.1 hypothetical protein 557511 8164305 TBMG_00468 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030394.1 556717 D 478434 CDS YP_003030395.1 253797394 8164306 557786..559072 1 NC_012943.1 isocitrate lyase icl 559072 8164306 TBMG_00469 Mycobacterium tuberculosis KZN 1435 isocitrate lyase icl YP_003030395.1 557786 D 478434 CDS YP_003030396.1 253797395 8164307 559154..560014 1 NC_012943.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 560014 8164307 TBMG_00470 Mycobacterium tuberculosis KZN 1435 3-hydroxybutyryl-CoA dehydrogenase YP_003030396.1 559154 D 478434 CDS YP_003030397.1 253797396 8164308 560129..561007 1 NC_012943.1 mycolic acid synthase umaA 561007 8164308 TBMG_00471 Mycobacterium tuberculosis KZN 1435 mycolic acid synthase umaA YP_003030397.1 560129 D 478434 CDS YP_003030398.1 253797397 8164309 complement(561107..561970) 1 NC_012943.1 mycolic acid synthase PcaA 561970 8164309 TBMG_00472 Mycobacterium tuberculosis KZN 1435 mycolic acid synthase PcaA YP_003030398.1 561107 R 478434 CDS YP_003030399.1 253797398 8164310 complement(562113..562553) 1 NC_012943.1 hypothetical protein 562553 8164310 TBMG_00473 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030399.1 562113 R 478434 CDS YP_003030400.1 253797399 8164311 complement(562484..562972) 1 NC_012943.1 hypothetical protein 562972 8164311 TBMG_00474 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030400.1 562484 R 478434 CDS YP_003030401.1 253797400 8164312 complement(562982..563752) 1 NC_012943.1 TetR family transcriptional regulator 563752 8164312 TBMG_00475 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030401.1 562982 R 478434 CDS YP_003030402.1 253797401 8164313 563823..565193 1 NC_012943.1 hypothetical protein 565193 8164313 TBMG_00476 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030402.1 563823 D 478434 CDS YP_003030403.1 253797402 8164314 565280..565702 1 NC_012943.1 transcriptional regulator 565702 8164314 TBMG_00477 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030403.1 565280 D 478434 CDS YP_003030404.1 253797403 8164315 566041..566655 1 NC_012943.1 iron-regulated heparin binding hemagglutinin hbhA 566655 8164315 TBMG_00478 Mycobacterium tuberculosis KZN 1435 iron-regulated heparin binding hemagglutinin hbhA YP_003030404.1 566041 D 478434 CDS YP_003030405.1 253797404 8164316 566767..567030 1 NC_012943.1 hypothetical protein 567030 8164316 TBMG_00479 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030405.1 566767 D 478434 CDS YP_003030406.1 253797405 8164317 567035..567481 1 NC_012943.1 hypothetical protein 567481 8164317 TBMG_00480 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030406.1 567035 D 478434 CDS YP_003030407.1 253797406 8164318 567481..568155 1 NC_012943.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 568155 8164318 TBMG_00481 Mycobacterium tuberculosis KZN 1435 deoxyribose-phosphate aldolase YP_003030407.1 567481 D 478434 CDS YP_003030408.1 253797407 8164319 complement(568180..569226) 1 NC_012943.1 hypothetical protein 569226 8164319 TBMG_00482 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030408.1 568180 R 478434 CDS YP_003030409.1 253797408 8164320 complement(569223..570065) 1 NC_012943.1 amidohydrolase 570065 8164320 TBMG_00483 Mycobacterium tuberculosis KZN 1435 amidohydrolase YP_003030409.1 569223 R 478434 CDS YP_003030410.1 253797409 8162581 complement(570191..570715) 1 NC_012943.1 hypothetical protein 570715 8162581 TBMG_00484 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030410.1 570191 R 478434 CDS YP_003030411.1 253797410 8162582 570742..571851 1 NC_012943.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 571851 murB 8162582 murB Mycobacterium tuberculosis KZN 1435 UDP-N-acetylenolpyruvoylglucosamine reductase YP_003030411.1 570742 D 478434 CDS YP_003030412.1 253797411 8164159 571913..573268 1 NC_012943.1 hypothetical protein 573268 8164159 TBMG_00486 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030412.1 571913 D 478434 CDS YP_003030413.1 253797412 8164160 complement(573249..574004) 1 NC_012943.1 short-chain type oxidoreductase 574004 8164160 TBMG_00487 Mycobacterium tuberculosis KZN 1435 short-chain type oxidoreductase YP_003030413.1 573249 R 478434 CDS YP_003030414.1 253797413 8164161 574187..575503 1 NC_012943.1 transcriptional regulator 575503 8164161 TBMG_00488 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030414.1 574187 D 478434 CDS YP_003030415.1 253797414 8164162 575551..576993 1 NC_012943.1 mannosyltransferase 576993 8164162 TBMG_00489 Mycobacterium tuberculosis KZN 1435 mannosyltransferase YP_003030415.1 575551 D 478434 CDS YP_003030416.1 253797415 8164163 576990..577541 1 NC_012943.1 hypothetical protein 577541 8164163 TBMG_00490 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030416.1 576990 D 478434 CDS YP_003030417.1 253797416 8164164 577846..578472 1 NC_012943.1 hypothetical protein 578472 8164164 TBMG_00491 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030417.1 577846 D 478434 CDS YP_003030418.1 253797417 8164165 578608..579378 1 NC_012943.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 579378 gpmA 8164165 gpmA Mycobacterium tuberculosis KZN 1435 phosphoglyceromutase YP_003030418.1 578608 D 478434 CDS YP_003030419.1 253797418 8164166 579552..580784 1 NC_012943.1 two component system sensor histidine kinase senX3 580784 8164166 TBMG_00493 Mycobacterium tuberculosis KZN 1435 two component system sensor histidine kinase senX3 YP_003030419.1 579552 D 478434 CDS YP_003030420.1 253797419 8164167 complement(580700..580906) 1 NC_012943.1 hypothetical protein 580906 8164167 TBMG_00494 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030420.1 580700 R 478434 CDS YP_003030421.1 253797420 8164168 580988..581671 1 NC_012943.1 two component system sensor protein regX3 581671 8164168 TBMG_00495 Mycobacterium tuberculosis KZN 1435 two component system sensor protein regX3 YP_003030421.1 580988 D 478434 CDS YP_003030422.1 253797421 8164169 complement(581668..583557) 1 NC_012943.1 oxidoreductase gmc-type 583557 8164169 TBMG_00496 Mycobacterium tuberculosis KZN 1435 oxidoreductase gmc-type YP_003030422.1 581668 R 478434 CDS YP_003030423.1 253797422 8164170 complement(583554..583883) 1 NC_012943.1 hypothetical protein 583883 8164170 TBMG_00497 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030423.1 583554 R 478434 CDS YP_003030424.1 253797423 8164171 complement(583880..584869) 1 NC_012943.1 hypothetical protein 584869 8164171 TBMG_00498 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030424.1 583880 R 478434 CDS YP_003030425.1 253797424 8164172 584874..585602 1 NC_012943.1 GntR family transcriptional regulator 585602 8164172 TBMG_00499 Mycobacterium tuberculosis KZN 1435 GntR family transcriptional regulator YP_003030425.1 584874 D 478434 CDS YP_003030426.1 253797425 8164173 complement(585603..586493) 1 NC_012943.1 hypothetical protein 586493 8164173 TBMG_00500 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030426.1 585603 R 478434 CDS YP_003030427.1 253797426 8164174 586525..587559 1 NC_012943.1 hypothetical protein 587559 8164174 TBMG_00501 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030427.1 586525 D 478434 CDS YP_003030428.1 253797427 8164175 587556..588488 1 NC_012943.1 hypothetical protein 588488 8164175 TBMG_00502 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030428.1 587556 D 478434 CDS YP_003030429.1 253797428 8164176 588504..589346 1 NC_012943.1 hypothetical protein 589346 8164176 TBMG_00503 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030429.1 588504 D 478434 CDS YP_003030430.1 253797429 8164177 589362..590237 1 NC_012943.1 hypothetical protein 590237 8164177 TBMG_00504 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030430.1 589362 D 478434 CDS YP_003030431.1 253797430 8164178 590262..591149 1 NC_012943.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 591149 8164178 TBMG_00505 Mycobacterium tuberculosis KZN 1435 pyrroline-5-carboxylate reductase YP_003030431.1 590262 D 478434 CDS YP_003030432.1 253797431 8164179 591290..591526 1 NC_012943.1 hypothetical protein 591526 8164179 TBMG_00506 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030432.1 591290 D 478434 CDS YP_003030433.1 253797432 8164180 591570..591755 1 NC_012943.1 hypothetical protein 591755 8164180 TBMG_00507 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030433.1 591570 D 478434 CDS YP_003030434.1 253797433 8164181 591833..592963 1 NC_012943.1 UDP-glucose 4-epimerase galE2 592963 8164181 TBMG_00508 Mycobacterium tuberculosis KZN 1435 UDP-glucose 4-epimerase galE2 YP_003030434.1 591833 D 478434 CDS YP_003030435.1 253797434 8164182 592970..594046 1 NC_012943.1 hypothetical protein 594046 8164182 TBMG_00509 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030435.1 592970 D 478434 CDS YP_003030436.1 253797435 8164183 complement(594050..595018) 1 NC_012943.1 cyclopropane-fatty-acyl-phospholipid synthase 2 cmaA2 595018 8164183 TBMG_00510 Mycobacterium tuberculosis KZN 1435 cyclopropane-fatty-acyl-phospholipid synthase 2 cmaA2 YP_003030436.1 594050 R 478434 CDS YP_003030437.1 253797436 8164184 complement(594981..595481) 1 NC_012943.1 hypothetical protein 595481 8164184 TBMG_00511 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030437.1 594981 R 478434 CDS YP_003030438.1 253797437 8164185 complement(595643..596764) 1 NC_012943.1 phosphoserine phosphatase serB1 596764 8164185 TBMG_00512 Mycobacterium tuberculosis KZN 1435 phosphoserine phosphatase serB1 YP_003030438.1 595643 R 478434 CDS YP_003030439.1 253797438 8164186 596938..597381 1 NC_012943.1 hypothetical protein 597381 8164186 TBMG_00513 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030439.1 596938 D 478434 CDS YP_003030440.1 253797439 8164187 597378..600284 1 NC_012943.1 transmembrane transporter mmpL2 600284 8164187 TBMG_00514 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL2 YP_003030440.1 597378 D 478434 CDS YP_003030441.1 253797440 8164188 600277..600570 1 NC_012943.1 hypothetical protein 600570 8164188 TBMG_00515 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030441.1 600277 D 478434 CDS YP_003030442.1 253797441 8164189 600620..602026 1 NC_012943.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 602026 hemA 8164189 hemA Mycobacterium tuberculosis KZN 1435 glutamyl-tRNA reductase YP_003030442.1 600620 D 478434 CDS YP_003030443.1 253797442 8164190 602027..602965 1 NC_012943.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 602965 hemC 8164190 hemC Mycobacterium tuberculosis KZN 1435 porphobilinogen deaminase YP_003030443.1 602027 D 478434 CDS YP_003030444.1 253797443 8164191 602989..604695 1 NC_012943.1 uroporphyrin-III C-methyltransferase 604695 8164191 TBMG_00518 Mycobacterium tuberculosis KZN 1435 uroporphyrin-III C-methyltransferase YP_003030444.1 602989 D 478434 CDS YP_003030445.1 253797444 8164192 604781..605770 1 NC_012943.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 605770 8164192 TBMG_00519 Mycobacterium tuberculosis KZN 1435 delta-aminolevulinic acid dehydratase YP_003030445.1 604781 D 478434 CDS YP_003030446.1 253797445 8164193 605783..606331 1 NC_012943.1 hypothetical protein 606331 8164193 TBMG_00520 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030446.1 605783 D 478434 CDS YP_003030447.1 253797446 8164194 606328..606627 1 NC_012943.1 hypothetical protein 606627 8164194 TBMG_00521 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030447.1 606328 D 478434 CDS YP_003030448.1 253797447 8164195 606706..608241 1 NC_012943.1 hypothetical protein 608241 8164195 TBMG_00522 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030448.1 606706 D 478434 CDS YP_003030449.1 253797448 8164196 complement(608238..608714) 1 NC_012943.1 hypothetical protein 608714 8164196 TBMG_00523 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030449.1 608238 R 478434 CDS YP_003030450.1 253797449 8164197 608925..610235 1 NC_012943.1 membrane acyltransferase 610235 8164197 TBMG_00524 Mycobacterium tuberculosis KZN 1435 membrane acyltransferase YP_003030450.1 608925 D 478434 CDS YP_003030451.1 253797450 8164198 610367..611062 1 NC_012943.1 hypothetical protein 611062 8164198 TBMG_00525 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030451.1 610367 D 478434 CDS YP_003030452.1 253797451 8164199 complement(611351..612253) 1 NC_012943.1 hypothetical protein 612253 8164199 TBMG_00526 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030452.1 611351 R 478434 CDS YP_003030453.1 253797452 8164200 612434..612784 1 NC_012943.1 methyltransferase/methylase 612784 8164200 TBMG_00527 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030453.1 612434 D 478434 CDS YP_003030454.1 253797453 8164201 612777..613082 1 NC_012943.1 methyltransferase/methylase 613082 8164201 TBMG_00528 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030454.1 612777 D 478434 CDS YP_003030455.1 253797454 8164202 613217..614521 1 NC_012943.1 gabA permease gabP 614521 8164202 TBMG_00529 Mycobacterium tuberculosis KZN 1435 gabA permease gabP YP_003030455.1 613217 D 478434 CDS YP_003030456.1 253797455 8164203 complement(614505..614909) 1 NC_012943.1 hypothetical protein 614909 8164203 TBMG_00530 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030456.1 614505 R 478434 CDS YP_003030457.1 253797456 8164204 615014..616402 1 NC_012943.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 616402 8164204 TBMG_00531 Mycobacterium tuberculosis KZN 1435 glutamate-1-semialdehyde aminotransferase YP_003030457.1 615014 D 478434 CDS YP_003030458.1 253797457 8164205 616402..617010 1 NC_012943.1 hypothetical protein 617010 8164205 TBMG_00532 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030458.1 616402 D 478434 CDS YP_003030459.1 253797458 8164206 617025..617675 1 NC_012943.1 thioredoxin 617675 8164206 TBMG_00533 Mycobacterium tuberculosis KZN 1435 thioredoxin YP_003030459.1 617025 D 478434 CDS YP_003030460.1 253797459 8164207 617672..618451 1 NC_012943.1 cytochrome C biogenesis protein ccdA 618451 8164207 TBMG_00534 Mycobacterium tuberculosis KZN 1435 cytochrome C biogenesis protein ccdA YP_003030460.1 617672 D 478434 CDS YP_003030461.1 253797460 8164208 618484..620073 1 NC_012943.1 hypothetical protein 620073 8164208 TBMG_00535 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030461.1 618484 D 478434 CDS YP_003030462.1 253797461 8164209 620070..621044 1 NC_012943.1 cytochrome C biogenesis protein ccsA 621044 8164209 TBMG_00536 Mycobacterium tuberculosis KZN 1435 cytochrome C biogenesis protein ccsA YP_003030462.1 620070 D 478434 CDS YP_003030463.1 253797462 8164210 621086..622303 1 NC_012943.1 hypothetical protein 622303 8164210 TBMG_00537 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030463.1 621086 D 478434 CDS YP_003030464.1 253797463 8164211 622508..622825 1 NC_012943.1 hypothetical protein 622825 8164211 TBMG_00538 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030464.1 622508 D 478434 CDS YP_003030465.1 253797464 8164212 622972..624840 1 NC_012943.1 PE-PGRS family protein 624840 8164212 TBMG_03988 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030465.1 622972 D 478434 CDS YP_003030466.1 253797465 8164213 complement(624736..625743) 1 NC_012943.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 625743 8164213 TBMG_00539 Mycobacterium tuberculosis KZN 1435 3-oxoacyl-ACP synthase YP_003030466.1 624736 R 478434 CDS YP_003030467.1 253797466 8164214 complement(625911..626702) 1 NC_012943.1 1,4-dihydroxy-2-naphthoate octaprenyltransferase 626702 8164214 TBMG_00540 Mycobacterium tuberculosis KZN 1435 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_003030467.1 625911 R 478434 CDS YP_003030468.1 253797467 8164215 626719..627513 1 NC_012943.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate; 5'-methylthioadenosine phosphorylase 627513 8164215 TBMG_00541 Mycobacterium tuberculosis KZN 1435 5'-methylthioadenosine phosphorylase YP_003030468.1 626719 D 478434 CDS YP_003030469.1 253797468 8164216 627554..628549 1 NC_012943.1 UDP-glucose 4-epimerase galE3 628549 8164216 TBMG_00542 Mycobacterium tuberculosis KZN 1435 UDP-glucose 4-epimerase galE3 YP_003030469.1 627554 D 478434 CDS YP_003030470.1 253797469 8164217 complement(628559..629992) 1 NC_012943.1 hypothetical protein 629992 8164217 TBMG_00543 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030470.1 628559 R 478434 CDS YP_003030471.1 253797470 8164218 630301..631947 1 NC_012943.1 hypothetical protein 631947 8164218 TBMG_00544 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030471.1 630301 D 478434 CDS YP_003030472.1 253797471 8164219 631980..632636 1 NC_012943.1 dolichyl-phosphate sugar synthase 632636 8164219 TBMG_00545 Mycobacterium tuberculosis KZN 1435 dolichyl-phosphate sugar synthase YP_003030472.1 631980 D 478434 CDS YP_003030473.1 253797472 8164220 632633..633295 1 NC_012943.1 hypothetical protein 633295 8164220 TBMG_00546 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030473.1 632633 D 478434 CDS YP_003030474.1 253797473 8164221 complement(633316..634665) 1 NC_012943.1 hypothetical protein 634665 8164221 TBMG_00547 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030474.1 633316 R 478434 CDS YP_003030475.1 253797474 8164222 complement(634677..635765) 1 NC_012943.1 O-succinylbenzoic acid--CoA ligase 635765 8164222 TBMG_00548 Mycobacterium tuberculosis KZN 1435 O-succinylbenzoic acid--CoA ligase YP_003030475.1 634677 R 478434 CDS YP_003030476.1 253797475 8164223 complement(635834..636136) 1 NC_012943.1 hypothetical protein 636136 8164223 TBMG_00549 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030476.1 635834 R 478434 CDS YP_003030477.1 253797476 8164224 complement(636196..636474) 1 NC_012943.1 hypothetical protein 636474 8164224 TBMG_00550 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030477.1 636196 R 478434 CDS YP_003030478.1 253797477 8164225 complement(636471..637724) 1 NC_012943.1 hypothetical protein 637724 8164225 TBMG_00551 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030478.1 636471 R 478434 CDS YP_003030479.1 253797478 8164226 complement(637844..638230) 1 NC_012943.1 hypothetical protein 638230 8164226 TBMG_00552 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030479.1 637844 R 478434 CDS YP_003030480.1 253797479 8164227 complement(638293..639177) 1 NC_012943.1 short chain dehydrogenase 639177 8164227 TBMG_00553 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003030480.1 638293 R 478434 CDS YP_003030481.1 253797480 8164228 complement(639273..640217) 1 NC_012943.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 640217 8164228 TBMG_00554 Mycobacterium tuberculosis KZN 1435 naphthoate synthase YP_003030481.1 639273 R 478434 CDS YP_003030482.1 253797481 8164229 complement(640489..640902) 1 NC_012943.1 toxin 640902 8164229 TBMG_00555 Mycobacterium tuberculosis KZN 1435 toxin YP_003030482.1 640489 R 478434 CDS YP_003030483.1 253797482 8164230 complement(640899..641165) 1 NC_012943.1 antitoxin 641165 8164230 TBMG_03989 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030483.1 640899 R 478434 CDS YP_003030484.1 253797483 8164231 complement(641357..643072) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 643072 8164231 TBMG_00556 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030484.1 641357 R 478434 CDS YP_003030485.1 253797484 8164232 643141..644754 1 NC_012943.1 hypothetical protein 644754 8164232 TBMG_00557 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030485.1 643141 D 478434 CDS YP_003030486.1 253797485 8164233 644751..645731 1 NC_012943.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 645731 8164233 TBMG_00558 Mycobacterium tuberculosis KZN 1435 O-succinylbenzoate synthase YP_003030486.1 644751 D 478434 CDS YP_003030487.1 253797486 8164234 645728..646516 1 NC_012943.1 peroxidase bpoC 646516 8164234 TBMG_00559 Mycobacterium tuberculosis KZN 1435 peroxidase bpoC YP_003030487.1 645728 D 478434 CDS YP_003030488.1 253797487 8164235 646559..648223 1 NC_012943.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 648223 8164235 TBMG_00560 Mycobacterium tuberculosis KZN 1435 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_003030488.1 646559 D 478434 CDS YP_003030489.1 253797488 8164236 648220..648735 1 NC_012943.1 hypothetical protein 648735 8164236 TBMG_00561 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030489.1 648220 D 478434 CDS YP_003030490.1 253797489 8164237 648797..649933 1 NC_012943.1 mannosyltransferase 649933 8164237 TBMG_00562 Mycobacterium tuberculosis KZN 1435 mannosyltransferase YP_003030490.1 648797 D 478434 CDS YP_003030491.1 253797490 8164238 649950..650654 1 NC_012943.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 650654 ubiE 8164238 ubiE Mycobacterium tuberculosis KZN 1435 ubiquinone/menaquinone biosynthesis methyltransferase YP_003030491.1 649950 D 478434 CDS YP_003030492.1 253797491 8164239 complement(650668..651006) 1 NC_012943.1 hypothetical protein 651006 8164239 TBMG_00564 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030492.1 650668 R 478434 CDS YP_003030493.1 253797492 8161970 complement(651040..651765) 1 NC_012943.1 benzoquinone methyltransferase 651765 8161970 TBMG_00565 Mycobacterium tuberculosis KZN 1435 benzoquinone methyltransferase YP_003030493.1 651040 R 478434 CDS YP_003030494.1 253797493 8161971 complement(651790..653016) 1 NC_012943.1 oxidoreductase 653016 8161971 TBMG_00566 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030494.1 651790 R 478434 CDS YP_003030495.1 253797494 8161972 653032..654039 1 NC_012943.1 polyprenyl synthetase 654039 8161972 TBMG_00567 Mycobacterium tuberculosis KZN 1435 polyprenyl synthetase YP_003030495.1 653032 D 478434 CDS YP_003030496.1 253797495 8161973 654140..655000 1 NC_012943.1 metalloprotease; heat shock protein HtpX 655000 8161973 TBMG_00568 Mycobacterium tuberculosis KZN 1435 heat shock protein HtpX YP_003030496.1 654140 D 478434 CDS YP_003030497.1 253797496 8161974 complement(655185..656270) 1 NC_012943.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 656270 8161974 TBMG_00569 Mycobacterium tuberculosis KZN 1435 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_003030497.1 655185 R 478434 CDS YP_003030498.1 253797497 8161975 complement(656271..657731) 1 NC_012943.1 monooxygenase 657731 8161975 TBMG_00570 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003030498.1 656271 R 478434 CDS YP_003030499.1 253797498 8161976 complement(657809..658300) 1 NC_012943.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 658300 8161976 TBMG_00571 Mycobacterium tuberculosis KZN 1435 nucleotide-binding protein YP_003030499.1 657809 R 478434 CDS YP_003030500.1 253797499 8161978 658579..659601 1 NC_012943.1 methyltransferase/methylase 659601 8161978 TBMG_00572 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030500.1 658579 D 478434 CDS YP_003030501.1 253797500 8161979 659711..661129 1 NC_012943.1 cytochrome P450 135B1 cyp135B1 661129 8161979 TBMG_00573 Mycobacterium tuberculosis KZN 1435 cytochrome P450 135B1 cyp135B1 YP_003030501.1 659711 D 478434 CDS YP_003030502.1 253797501 8161980 661195..661530 1 NC_012943.1 hypothetical protein 661530 8161980 TBMG_00574 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030502.1 661195 D 478434 CDS YP_003030503.1 253797502 8161981 661514..663634 1 NC_012943.1 ribonucleoside-diphosphate reductase large subunit nrdZ 663634 8161981 TBMG_00575 Mycobacterium tuberculosis KZN 1435 ribonucleoside-diphosphate reductase large subunit nrdZ YP_003030503.1 661514 D 478434 CDS YP_003030504.1 253797503 8161982 complement(663748..665079) 1 NC_012943.1 hypothetical protein 665079 8161982 TBMG_00576 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030504.1 663748 R 478434 CDS YP_003030505.1 253797504 8161983 complement(665303..665644) 1 NC_012943.1 hypothetical protein 665644 8161983 TBMG_00577 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030505.1 665303 R 478434 CDS YP_003030506.1 253797505 8161984 complement(665695..665862) 1 NC_012943.1 hypothetical protein 665862 8161984 TBMG_03990 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030506.1 665695 R 478434 CDS YP_003030507.1 253797506 8161985 complement(666112..667503) 1 NC_012943.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 667503 8161985 TBMG_00578 Mycobacterium tuberculosis KZN 1435 nicotinate phosphoribosyltransferase YP_003030507.1 666112 R 478434 CDS YP_003030508.1 253797507 8161986 complement(667513..668655) 1 NC_012943.1 hypothetical protein 668655 8161986 TBMG_00579 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030508.1 667513 R 478434 CDS YP_003030509.1 253797508 8161987 complement(668840..670006) 1 NC_012943.1 hypothetical protein 670006 8161987 TBMG_00580 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030509.1 668840 R 478434 CDS YP_003030510.1 253797509 8161988 670100..671413 1 NC_012943.1 transcriptional regulator, arsR-family 671413 8161988 TBMG_00581 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, arsR-family YP_003030510.1 670100 D 478434 CDS YP_003030511.1 253797510 8161989 671427..672212 1 NC_012943.1 hypothetical protein 672212 8161989 TBMG_00582 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030511.1 671427 D 478434 CDS YP_003030512.1 253797511 8161990 complement(672257..676168) 1 NC_012943.1 PE-PGRS family protein 676168 8161990 TBMG_03991 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030512.1 672257 R 478434 CDS YP_003030513.1 253797512 8161991 676284..676562 1 NC_012943.1 hypothetical protein 676562 8161991 TBMG_00585 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030513.1 676284 D 478434 CDS YP_003030514.1 253797513 8161992 676490..677248 1 NC_012943.1 hypothetical protein 677248 8161992 TBMG_00586 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030514.1 676490 D 478434 CDS YP_003030515.1 253797514 8161993 complement(677377..677955) 1 NC_012943.1 hypothetical protein 677955 8161993 TBMG_00587 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030515.1 677377 R 478434 CDS YP_003030516.1 253797515 8161994 677962..678177 1 NC_012943.1 antitoxin 678177 8161994 TBMG_00588 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030516.1 677962 D 478434 CDS YP_003030517.1 253797516 8161995 678174..678581 1 NC_012943.1 toxin 678581 8161995 TBMG_00589 Mycobacterium tuberculosis KZN 1435 toxin YP_003030517.1 678174 D 478434 CDS YP_003030518.1 253797517 8161996 complement(678641..679327) 1 NC_012943.1 hypothetical protein 679327 8161996 TBMG_00590 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030518.1 678641 R 478434 CDS YP_003030519.1 253797518 8161997 679481..682114 1 NC_012943.1 hypothetical protein 682114 8161997 TBMG_00591 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030519.1 679481 D 478434 CDS YP_003030520.1 253797519 8161998 complement(682137..684524) 1 NC_012943.1 hypothetical protein 684524 8161998 TBMG_00592 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030520.1 682137 R 478434 CDS YP_003030521.1 253797520 8161999 684662..685384 1 NC_012943.1 GntR family transcriptional regulator 685384 8161999 TBMG_00593 Mycobacterium tuberculosis KZN 1435 GntR family transcriptional regulator YP_003030521.1 684662 D 478434 CDS YP_003030522.1 253797521 8162000 685381..686178 1 NC_012943.1 hypothetical protein 686178 8162000 TBMG_00594 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030522.1 685381 D 478434 CDS YP_003030523.1 253797522 8162001 686180..687067 1 NC_012943.1 hypothetical protein 687067 8162001 TBMG_00595 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030523.1 686180 D 478434 CDS YP_003030524.1 253797523 8162002 687073..688287 1 NC_012943.1 MCE-family protein mce2A 688287 8162002 TBMG_00596 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce2A YP_003030524.1 687073 D 478434 CDS YP_003030525.1 253797524 8162003 688284..689111 1 NC_012943.1 MCE-family protein mce2B 689111 8162003 TBMG_00597 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce2B YP_003030525.1 688284 D 478434 CDS YP_003030526.1 253797525 8162004 689060..689314 1 NC_012943.1 MCE-family related protein 689314 8162004 TBMG_00598 Mycobacterium tuberculosis KZN 1435 MCE-family related protein YP_003030526.1 689060 D 478434 CDS YP_003030527.1 253797526 8162005 689311..690756 1 NC_012943.1 MCE-family protein mce2C 690756 8162005 TBMG_00599 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce2C YP_003030527.1 689311 D 478434 CDS YP_003030528.1 253797527 8162006 690753..692279 1 NC_012943.1 MCE-family protein mce2D 692279 8162006 TBMG_00600 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce2D YP_003030528.1 690753 D 478434 CDS YP_003030529.1 253797528 8162007 692276..693484 1 NC_012943.1 MCE-family lipoprotein mce2E 693484 8162007 TBMG_00601 Mycobacterium tuberculosis KZN 1435 MCE-family lipoprotein mce2E YP_003030529.1 692276 D 478434 CDS YP_003030530.1 253797529 8162008 693489..695039 1 NC_012943.1 MCE-family protein mce2F 695039 8162008 TBMG_00602 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce2F YP_003030530.1 693489 D 478434 CDS YP_003030531.1 253797530 8162009 complement(695091..695483) 1 NC_012943.1 toxin 695483 8162009 TBMG_00603 Mycobacterium tuberculosis KZN 1435 toxin YP_003030531.1 695091 R 478434 CDS YP_003030532.1 253797531 8162010 complement(695480..695737) 1 NC_012943.1 antitoxin 695737 8162010 TBMG_00604 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030532.1 695480 R 478434 CDS YP_003030533.1 253797532 8162011 complement(695920..697155) 1 NC_012943.1 hypothetical protein 697155 8162011 TBMG_00605 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030533.1 695920 R 478434 CDS YP_003030534.1 253797533 8162012 complement(697406..697819) 1 NC_012943.1 toxin 697819 8162012 TBMG_00606 Mycobacterium tuberculosis KZN 1435 toxin YP_003030534.1 697406 R 478434 CDS YP_003030535.1 253797534 8162013 complement(697816..698052) 1 NC_012943.1 antitoxin 698052 8162013 TBMG_00607 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030535.1 697816 R 478434 CDS YP_003030536.1 253797535 8162014 complement(698156..699289) 1 NC_012943.1 two component system sensor kinase 699289 8162014 TBMG_00608 Mycobacterium tuberculosis KZN 1435 two component system sensor kinase YP_003030536.1 698156 R 478434 CDS YP_003030537.1 253797536 8162015 complement(699290..700051) 1 NC_012943.1 two component system transcriptional regulator tcrA 700051 8162015 TBMG_00609 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator tcrA YP_003030537.1 699290 R 478434 CDS YP_003030538.1 253797537 8162016 700108..700419 1 NC_012943.1 hypothetical protein 700419 8162016 TBMG_00610 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030538.1 700108 D 478434 CDS YP_003030539.1 253797538 8162017 700515..701441 1 NC_012943.1 hypothetical protein 701441 8162017 TBMG_00611 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030539.1 700515 D 478434 CDS YP_003030540.1 253797539 8162018 701658..702266 1 NC_012943.1 resolvase 702266 8162018 TBMG_00612 Mycobacterium tuberculosis KZN 1435 resolvase YP_003030540.1 701658 D 478434 CDS YP_003030541.1 253797540 8162019 702268..703011 1 NC_012943.1 transposase 703011 8162019 TBMG_00613 Mycobacterium tuberculosis KZN 1435 transposase YP_003030541.1 702268 D 478434 CDS YP_003030542.1 253797541 8162020 702981..703451 1 NC_012943.1 hypothetical protein 703451 8162020 TBMG_00614 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030542.1 702981 D 478434 CDS YP_003030543.1 253797542 8162021 703496..703741 1 NC_012943.1 antitoxin 703741 8162021 TBMG_00615 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030543.1 703496 D 478434 CDS YP_003030544.1 253797543 8162022 703738..704139 1 NC_012943.1 toxin 704139 8162022 TBMG_03992 Mycobacterium tuberculosis KZN 1435 toxin YP_003030544.1 703738 D 478434 CDS YP_003030545.1 253797544 8162023 704082..704309 1 NC_012943.1 hypothetical protein 704309 8162023 TBMG_03993 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030545.1 704082 D 478434 CDS YP_003030546.1 253797545 8162024 704237..704464 1 NC_012943.1 hypothetical protein 704464 8162024 TBMG_03994 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030546.1 704237 D 478434 CDS YP_003030547.1 253797546 8162025 704676..705011 1 NC_012943.1 hypothetical protein 705011 8162025 TBMG_00617 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030547.1 704676 D 478434 CDS YP_003030548.1 253797547 8162026 complement(705004..706161) 1 NC_012943.1 hypothetical protein 706161 8162026 TBMG_00618 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030548.1 705004 R 478434 CDS YP_003030549.1 253797548 8162027 complement(706213..706596) 1 NC_012943.1 hypothetical protein 706596 8162027 TBMG_00619 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030549.1 706213 R 478434 CDS YP_003030550.1 253797549 8162029 706576..707181 1 NC_012943.1 hypothetical protein 707181 8162029 TBMG_00620 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030550.1 706576 D 478434 CDS YP_003030551.1 253797550 8162028 complement(707200..709767) 1 NC_012943.1 hypothetical protein 709767 8162028 TBMG_00621 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030551.1 707200 R 478434 CDS YP_003030552.1 253797551 8162031 709707..710600 1 NC_012943.1 hypothetical protein 710600 8162031 TBMG_00622 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030552.1 709707 D 478434 CDS YP_003030553.1 253797552 8162030 710597..710839 1 NC_012943.1 hypothetical protein 710839 8162030 TBMG_00623 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030553.1 710597 D 478434 CDS YP_003030554.1 253797553 8162032 complement(710836..711102) 1 NC_012943.1 hypothetical protein 711102 8162032 TBMG_00624 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030554.1 710836 R 478434 CDS YP_003030555.1 253797554 8162034 711034..711261 1 NC_012943.1 antitoxin 711261 8162034 TBMG_00625 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030555.1 711034 D 478434 CDS YP_003030556.1 253797555 8162033 711258..711659 1 NC_012943.1 toxin 711659 8162033 TBMG_00626 Mycobacterium tuberculosis KZN 1435 toxin YP_003030556.1 711258 D 478434 CDS YP_003030557.1 253797556 8162035 711788..712483 1 NC_012943.1 galactose-1-phosphate uridylyltransferase galTa 712483 8162035 TBMG_00627 Mycobacterium tuberculosis KZN 1435 galactose-1-phosphate uridylyltransferase galTa YP_003030557.1 711788 D 478434 CDS YP_003030558.1 253797557 8162036 712501..712971 1 NC_012943.1 galactose-1-phosphate uridylyltransferase galTb 712971 8162036 TBMG_00628 Mycobacterium tuberculosis KZN 1435 galactose-1-phosphate uridylyltransferase galTb YP_003030558.1 712501 D 478434 CDS YP_003030559.1 253797558 8162037 712968..714059 1 NC_012943.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 714059 8162037 TBMG_00629 Mycobacterium tuberculosis KZN 1435 galactokinase YP_003030559.1 712968 D 478434 CDS YP_003030560.1 253797559 8162038 714445..715518 1 NC_012943.1 hypothetical protein 715518 8162038 TBMG_00630 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030560.1 714445 D 478434 CDS YP_003030561.1 253797560 8162039 715544..716569 1 NC_012943.1 hypothetical protein 716569 8162039 TBMG_00631 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030561.1 715544 D 478434 CDS YP_003030562.1 253797561 8162040 716662..716916 1 NC_012943.1 antitoxin 716916 8162040 TBMG_00632 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030562.1 716662 D 478434 CDS YP_003030563.1 253797562 8162041 716916..717311 1 NC_012943.1 toxin 717311 8162041 TBMG_00633 Mycobacterium tuberculosis KZN 1435 toxin YP_003030563.1 716916 D 478434 CDS YP_003030564.1 253797563 8162042 complement(717405..718145) 1 NC_012943.1 hypothetical protein 718145 8162042 TBMG_00634 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030564.1 717405 R 478434 CDS YP_003030565.1 253797564 8162043 718277..718537 1 NC_012943.1 antitoxin 718537 8162043 TBMG_00635 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030565.1 718277 D 478434 CDS YP_003030566.1 253797565 8162044 718534..718941 1 NC_012943.1 toxin 718941 8162044 TBMG_00636 Mycobacterium tuberculosis KZN 1435 toxin YP_003030566.1 718534 D 478434 CDS YP_003030567.1 253797566 8162045 complement(719013..720164) 1 NC_012943.1 hypothetical protein 720164 8162045 TBMG_00637 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030567.1 719013 R 478434 CDS YP_003030568.1 253797567 8162046 complement(720257..721984) 1 NC_012943.1 exonuclease subunit V alpha recD 721984 8162046 TBMG_00638 Mycobacterium tuberculosis KZN 1435 exonuclease subunit V alpha recD YP_003030568.1 720257 R 478434 CDS YP_003030569.1 253797568 8162047 complement(721981..725265) 1 NC_012943.1 exonuclease subunit V beta recB 725265 8162047 TBMG_00639 Mycobacterium tuberculosis KZN 1435 exonuclease subunit V beta recB YP_003030569.1 721981 R 478434 CDS YP_003030570.1 253797569 8162048 complement(725265..728558) 1 NC_012943.1 exonuclease subunit V gamma recC 728558 8162048 TBMG_00640 Mycobacterium tuberculosis KZN 1435 exonuclease subunit V gamma recC YP_003030570.1 725265 R 478434 CDS YP_003030571.1 253797570 8162049 complement(728835..729530) 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 729530 8162049 TBMG_00641 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003030571.1 728835 R 478434 CDS YP_003030572.1 253797571 8162050 complement(729579..730439) 1 NC_012943.1 hypothetical protein 730439 8162050 TBMG_00642 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030572.1 729579 R 478434 CDS YP_003030573.1 253797572 8164240 complement(730572..731285) 1 NC_012943.1 glyoxalase II 731285 8164240 TBMG_00643 Mycobacterium tuberculosis KZN 1435 glyoxalase II YP_003030573.1 730572 R 478434 CDS YP_003030574.1 253797573 8163290 731365..731616 1 NC_012943.1 hypothetical protein 731616 8163290 TBMG_00644 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030574.1 731365 D 478434 CDS YP_003030575.1 253797574 8163293 731964..732131 1 NC_012943.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 732131 rpmG 8163293 rpmG Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L33 YP_003030575.1 731964 D 478434 CDS YP_003030576.1 253797575 8163294 732182..732658 1 NC_012943.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadA 732658 8163294 TBMG_00646 Mycobacterium tuberculosis KZN 1435 (3R)-hydroxyacyl-ACP dehydratase subunit HadA YP_003030576.1 732182 D 478434 CDS YP_003030577.1 253797576 8163295 732576..733073 1 NC_012943.1 functions as a heterodimer along with HadA or HadC in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadB 733073 8163295 TBMG_00647 Mycobacterium tuberculosis KZN 1435 (3R)-hydroxyacyl-ACP dehydratase subunit HadB YP_003030577.1 732576 D 478434 CDS YP_003030578.1 253797577 8163296 733077..733577 1 NC_012943.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadC 733577 8163296 TBMG_00648 Mycobacterium tuberculosis KZN 1435 (3R)-hydroxyacyl-ACP dehydratase subunit HadC YP_003030578.1 733077 D 478434 CDS YP_003030579.1 253797578 8163298 733989..734474 1 NC_012943.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 734474 secE 8163298 secE Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit SecE YP_003030579.1 733989 D 478434 CDS YP_003030580.1 253797579 8163299 734506..735222 1 NC_012943.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 735222 nusG 8163299 nusG Mycobacterium tuberculosis KZN 1435 transcription antitermination protein NusG YP_003030580.1 734506 D 478434 CDS YP_003030581.1 253797580 8163300 735274..735702 1 NC_012943.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 735702 rplK 8163300 rplK Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L11 YP_003030581.1 735274 D 478434 CDS YP_003030582.1 253797581 8163301 735769..736476 1 NC_012943.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 736476 rplA 8163301 rplA Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L1 YP_003030582.1 735769 D 478434 CDS YP_003030583.1 253797582 8163302 complement(736550..737497) 1 NC_012943.1 methoxy mycolic acid synthase 4 mmaA4 737497 8163302 TBMG_00653 Mycobacterium tuberculosis KZN 1435 methoxy mycolic acid synthase 4 mmaA4 YP_003030583.1 736550 R 478434 CDS YP_003030584.1 253797583 8163303 complement(737520..738413) 1 NC_012943.1 methoxy mycolic acid synthase 3 mmaA3 738413 8163303 TBMG_00654 Mycobacterium tuberculosis KZN 1435 methoxy mycolic acid synthase 3 mmaA3 YP_003030584.1 737520 R 478434 CDS YP_003030585.1 253797584 8163304 complement(738549..739502) 1 NC_012943.1 methoxy mycolic acid synthase 2 mmaA2 739502 8163304 TBMG_00655 Mycobacterium tuberculosis KZN 1435 methoxy mycolic acid synthase 2 mmaA2 YP_003030585.1 738549 R 478434 CDS YP_003030586.1 253797585 8163305 complement(739579..740469) 1 NC_012943.1 methoxy mycolic acid synthase 1 mmaA1 740469 8163305 TBMG_00656 Mycobacterium tuberculosis KZN 1435 methoxy mycolic acid synthase 1 mmaA1 YP_003030586.1 739579 R 478434 CDS YP_003030587.1 253797586 8163306 complement(740486..741391) 1 NC_012943.1 lipase/esterase 741391 8163306 TBMG_00657 Mycobacterium tuberculosis KZN 1435 lipase/esterase YP_003030587.1 740486 R 478434 CDS YP_003030588.1 253797587 8163307 complement(741403..742869) 1 NC_012943.1 hypothetical protein 742869 8163307 TBMG_00658 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030588.1 741403 R 478434 CDS YP_003030589.1 253797588 8163308 742955..747151 1 NC_012943.1 alpha-mannosidase 747151 8163308 TBMG_00659 Mycobacterium tuberculosis KZN 1435 alpha-mannosidase YP_003030589.1 742955 D 478434 CDS YP_003030590.1 253797589 8163309 747148..747822 1 NC_012943.1 malonyl CoA-acyl carrier protein transacylase fabD2 747822 8163309 TBMG_00660 Mycobacterium tuberculosis KZN 1435 malonyl CoA-acyl carrier protein transacylase fabD2 YP_003030590.1 747148 D 478434 CDS YP_003030591.1 253797590 8163310 747822..748730 1 NC_012943.1 sugar kinase 748730 8163310 TBMG_00661 Mycobacterium tuberculosis KZN 1435 sugar kinase YP_003030591.1 747822 D 478434 CDS YP_003030592.1 253797591 8163311 749061..749597 1 NC_012943.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 749597 rplJ 8163311 rplJ Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L10 YP_003030592.1 749061 D 478434 CDS YP_003030593.1 253797592 8163312 749634..750026 1 NC_012943.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 750026 rplL 8163312 rplL Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L7/L12 YP_003030593.1 749634 D 478434 CDS YP_003030594.1 253797593 8163313 complement(750019..750786) 1 NC_012943.1 TetR family transcriptional regulator 750786 8163313 TBMG_00664 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030594.1 750019 R 478434 CDS YP_003030595.1 253797594 8163315 750785..752290 1 NC_012943.1 dioxygenase 752290 8163315 TBMG_00665 Mycobacterium tuberculosis KZN 1435 dioxygenase YP_003030595.1 750785 D 478434 CDS YP_003030596.1 253797595 8163314 752302..753381 1 NC_012943.1 ribonucleotide-transport ATP-binding protein ABC transporter mkl 753381 8163314 TBMG_00666 Mycobacterium tuberculosis KZN 1435 ribonucleotide-transport ATP-binding protein ABC transporter mkl YP_003030596.1 752302 D 478434 CDS YP_003030597.1 253797596 8163316 complement(753769..754152) 1 NC_012943.1 toxin 754152 8163316 TBMG_00667 Mycobacterium tuberculosis KZN 1435 toxin YP_003030597.1 753769 R 478434 CDS YP_003030598.1 253797597 8163317 complement(754247..754402) 1 NC_012943.1 antitoxin 754402 8163317 TBMG_00668 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030598.1 754247 R 478434 CDS YP_003030599.1 253797598 8163318 complement(754478..755194) 1 NC_012943.1 hypothetical protein 755194 8163318 TBMG_00669 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030599.1 754478 R 478434 CDS YP_003030600.1 253797599 8163319 complement(755470..755778) 1 NC_012943.1 toxin 755778 8163319 TBMG_00670 Mycobacterium tuberculosis KZN 1435 toxin YP_003030600.1 755470 R 478434 CDS YP_003030601.1 253797600 8163320 complement(755765..756010) 1 NC_012943.1 antitoxin 756010 8163320 TBMG_00671 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030601.1 755765 R 478434 CDS YP_003030602.1 253797601 8163321 complement(756120..756557) 1 NC_012943.1 toxin 756557 8163321 TBMG_00672 Mycobacterium tuberculosis KZN 1435 toxin YP_003030602.1 756120 R 478434 CDS YP_003030603.1 253797602 8163322 complement(756554..756922) 1 NC_012943.1 antitoxin 756922 8163322 TBMG_00673 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030603.1 756554 R 478434 CDS YP_003030604.1 253797603 8163323 756922..759285 1 NC_012943.1 arylsulfatase 759285 8163323 TBMG_00674 Mycobacterium tuberculosis KZN 1435 arylsulfatase YP_003030604.1 756922 D 478434 CDS YP_003030605.1 253797604 8163324 759317..759589 1 NC_012943.1 antitoxin 759589 8163324 TBMG_00675 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030605.1 759317 D 478434 CDS YP_003030606.1 253797605 8163325 759586..759924 1 NC_012943.1 toxin 759924 8163325 TBMG_00676 Mycobacterium tuberculosis KZN 1435 toxin YP_003030606.1 759586 D 478434 CDS YP_003030607.1 253797606 8163326 759921..760094 1 NC_012943.1 hypothetical protein 760094 8163326 TBMG_00677 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030607.1 759921 D 478434 CDS YP_003030608.1 253797607 8163327 760079..760309 1 NC_012943.1 hypothetical protein 760309 8163327 TBMG_00678 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030608.1 760079 D 478434 CDS YP_003030609.1 253797608 8163328 760574..764110 1 NC_012943.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 764110 rpoB 8163328 rpoB Mycobacterium tuberculosis KZN 1435 DNA-directed RNA polymerase subunit beta YP_003030609.1 760574 D 478434 CDS YP_003030610.1 253797609 8163329 764155..768105 1 NC_012943.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 768105 8163329 TBMG_00680 Mycobacterium tuberculosis KZN 1435 DNA-directed RNA polymerase subunit beta' YP_003030610.1 764155 D 478434 CDS YP_003030611.1 253797610 8163330 complement(768102..768422) 1 NC_012943.1 hypothetical protein 768422 8163330 TBMG_00681 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030611.1 768102 R 478434 CDS YP_003030612.1 253797611 8163331 complement(768469..770382) 1 NC_012943.1 hydrolase 770382 8163331 TBMG_00682 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003030612.1 768469 R 478434 CDS YP_003030613.1 253797612 8163332 770675..771334 1 NC_012943.1 truncated CDS; endonuclease IV end 771334 8163332 TBMG_00683 Mycobacterium tuberculosis KZN 1435 endonuclease IV end YP_003030613.1 770675 D 478434 CDS YP_003030614.1 253797613 8163333 771366..772208 1 NC_012943.1 hypothetical protein 772208 8163333 TBMG_00684 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030614.1 771366 D 478434 CDS YP_003030615.1 253797614 8163334 772268..773896 1 NC_012943.1 acyl-CoA dehydrogenase 773896 8163334 TBMG_00685 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030615.1 772268 D 478434 CDS YP_003030616.1 253797615 8163335 773907..774845 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 774845 8163335 TBMG_00686 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003030616.1 773907 D 478434 CDS YP_003030617.1 253797616 8163336 774848..775570 1 NC_012943.1 hypothetical protein 775570 8163336 TBMG_00687 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030617.1 774848 D 478434 CDS YP_003030618.1 253797617 8163337 775567..776358 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 776358 8163337 TBMG_00688 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003030618.1 775567 D 478434 CDS YP_003030619.1 253797618 8163338 complement(776370..779264) 1 NC_012943.1 transmembrane transporter mmpL5 779264 8163338 TBMG_00689 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL5 YP_003030619.1 776370 R 478434 CDS YP_003030620.1 253797619 8163339 complement(779261..779689) 1 NC_012943.1 hypothetical protein 779689 8163339 TBMG_00690 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030620.1 779261 R 478434 CDS YP_003030621.1 253797620 8163340 779774..780271 1 NC_012943.1 hypothetical protein 780271 8163340 TBMG_00691 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030621.1 779774 D 478434 CDS YP_003030622.1 253797621 8163341 complement(780327..780824) 1 NC_012943.1 hypothetical protein 780824 8163341 TBMG_00692 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030622.1 780327 R 478434 CDS YP_003030623.1 253797622 8163342 complement(780826..781200) 1 NC_012943.1 hypothetical protein 781200 8163342 TBMG_00693 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030623.1 780826 R 478434 CDS YP_003030624.1 253797623 8163343 781439..782095 1 NC_012943.1 TetR family transcriptional regulator 782095 8163343 TBMG_00694 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030624.1 781439 D 478434 CDS YP_003030625.1 253797624 8163344 782344..782718 1 NC_012943.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 782718 rpsL 8163344 rpsL Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S12 YP_003030625.1 782344 D 478434 CDS YP_003030626.1 253797625 8163345 782718..783188 1 NC_012943.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 783188 8163345 TBMG_00696 Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S7 YP_003030626.1 782718 D 478434 CDS YP_003030627.1 253797626 8163346 783269..785374 1 NC_012943.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 785374 8163346 TBMG_00697 Mycobacterium tuberculosis KZN 1435 elongation factor G YP_003030627.1 783269 D 478434 CDS YP_003030628.1 253797627 8163347 785605..786795 1 NC_012943.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 786795 8163347 TBMG_00698 Mycobacterium tuberculosis KZN 1435 elongation factor Tu YP_003030628.1 785605 D 478434 CDS YP_003030629.1 253797628 8163348 786933..787730 1 NC_012943.1 hypothetical protein 787730 8163348 TBMG_00699 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030629.1 786933 D 478434 CDS YP_003030630.1 253797629 8163349 787883..788710 1 NC_012943.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 788710 fabG 8163349 fabG Mycobacterium tuberculosis KZN 1435 3-ketoacyl-ACP reductase YP_003030630.1 787883 D 478434 CDS YP_003030631.1 253797630 8163350 788724..789944 1 NC_012943.1 ferredoxin reductase 789944 8163350 TBMG_00701 Mycobacterium tuberculosis KZN 1435 ferredoxin reductase YP_003030631.1 788724 D 478434 CDS YP_003030632.1 253797631 8163351 complement(789941..790195) 1 NC_012943.1 hypothetical protein 790195 8163351 TBMG_00702 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030632.1 789941 R 478434 CDS YP_003030633.1 253797632 8163352 complement(790808..791857) 1 NC_012943.1 hypothetical protein 791857 8163352 TBMG_00703 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030633.1 790808 R 478434 CDS YP_003030634.1 253797633 8163353 complement(791854..792450) 1 NC_012943.1 transcriptional regulator 792450 8163353 TBMG_00704 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030634.1 791854 R 478434 CDS YP_003030635.1 253797634 8163354 792615..792944 1 NC_012943.1 hypothetical protein 792944 8163354 TBMG_00705 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030635.1 792615 D 478434 CDS YP_003030636.1 253797635 8163355 792941..794116 1 NC_012943.1 coenzyme pqq synthesis protein E pqqE 794116 8163355 TBMG_00706 Mycobacterium tuberculosis KZN 1435 coenzyme pqq synthesis protein E pqqE YP_003030636.1 792941 D 478434 CDS YP_003030637.1 253797636 8163356 794119..795309 1 NC_012943.1 L-lactate dehydrogenase lldD1 795309 8163356 TBMG_00707 Mycobacterium tuberculosis KZN 1435 L-lactate dehydrogenase lldD1 YP_003030637.1 794119 D 478434 CDS YP_003030638.1 253797637 8163357 795499..796254 1 NC_012943.1 hypothetical protein 796254 8163357 TBMG_00708 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030638.1 795499 D 478434 CDS YP_003030639.1 253797638 8163358 796303..797715 1 NC_012943.1 membrane sugar transferase 797715 8163358 TBMG_00709 Mycobacterium tuberculosis KZN 1435 membrane sugar transferase YP_003030639.1 796303 D 478434 CDS YP_003030640.1 253797639 8163359 797717..799156 1 NC_012943.1 dehydrogenase 799156 8163359 TBMG_00710 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003030640.1 797717 D 478434 CDS YP_003030641.1 253797640 8163360 799617..800228 1 NC_012943.1 hypothetical protein 800228 8163360 TBMG_03995 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030641.1 799617 D 478434 CDS YP_003030642.1 253797641 8163361 complement(799944..800591) 1 NC_012943.1 hypothetical protein 800591 8163361 TBMG_00711 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030642.1 799944 R 478434 CDS YP_003030643.1 253797642 8163362 complement(800888..801178) 1 NC_012943.1 hypothetical protein 801178 8163362 TBMG_00712 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030643.1 800888 R 478434 CDS YP_003030644.1 253797643 8163363 801271..801576 1 NC_012943.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 801576 rpsJ 8163363 rpsJ Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S10 YP_003030644.1 801271 D 478434 CDS YP_003030645.1 253797644 8163364 801593..802246 1 NC_012943.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 802246 rplC 8163364 rplC Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L3 YP_003030645.1 801593 D 478434 CDS YP_003030646.1 253797645 8163365 802246..802917 1 NC_012943.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 802917 rplD 8163365 rplD Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L4 YP_003030646.1 802246 D 478434 CDS YP_003030647.1 253797646 8163366 802917..803219 1 NC_012943.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 803219 rplW 8163366 rplW Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L23 YP_003030647.1 802917 D 478434 CDS YP_003030648.1 253797647 8163367 803528..804370 1 NC_012943.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 804370 rplB 8163367 rplB Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L2 YP_003030648.1 803528 D 478434 CDS YP_003030649.1 253797648 8163368 804411..804692 1 NC_012943.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 804692 rpsS 8163368 rpsS Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S19 YP_003030649.1 804411 D 478434 CDS YP_003030650.1 253797649 8163369 804689..805282 1 NC_012943.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 805282 rplV 8163369 rplV Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L22 YP_003030650.1 804689 D 478434 CDS YP_003030651.1 253797650 8163370 805282..806106 1 NC_012943.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 806106 rpsC 8163370 rpsC Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S3 YP_003030651.1 805282 D 478434 CDS YP_003030652.1 253797651 8163371 806110..806526 1 NC_012943.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 806526 rplP 8163371 rplP Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L16 YP_003030652.1 806110 D 478434 CDS YP_003030653.1 253797652 8163372 806526..806759 1 NC_012943.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 806759 8163372 TBMG_00723 Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L29 YP_003030653.1 806526 D 478434 CDS YP_003030654.1 253797653 8163373 806798..807166 1 NC_012943.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 807166 rpsQ 8163373 rpsQ Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S17 YP_003030654.1 806798 D 478434 CDS YP_003030655.1 253797654 8163374 807335..809698 1 NC_012943.1 arylsulfatase 809698 8163374 TBMG_00725 Mycobacterium tuberculosis KZN 1435 arylsulfatase YP_003030655.1 807335 D 478434 CDS YP_003030656.1 253797655 8163375 809746..810645 1 NC_012943.1 hypothetical protein 810645 8163375 TBMG_00726 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030656.1 809746 D 478434 CDS YP_003030657.1 253797656 8163376 810946..811887 1 NC_012943.1 hypothetical protein 811887 8163376 TBMG_00727 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030657.1 810946 D 478434 CDS YP_003030658.1 253797657 8162905 812373..812741 1 NC_012943.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 812741 rplN 8162905 rplN Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L14 YP_003030658.1 812373 D 478434 CDS YP_003030659.1 253797658 8162906 812742..813059 1 NC_012943.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 813059 rplX 8162906 rplX Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L24 YP_003030659.1 812742 D 478434 CDS YP_003030660.1 253797659 8162907 813059..813622 1 NC_012943.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 813622 rplE 8162907 rplE Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L5 YP_003030660.1 813059 D 478434 CDS YP_003030661.1 253797660 8162908 813627..813809 1 NC_012943.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 813809 rpsN 8162908 rpsN Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S14 YP_003030661.1 813627 D 478434 CDS YP_003030662.1 253797661 8162909 813976..814374 1 NC_012943.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 814374 rpsH 8162909 rpsH Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S8 YP_003030662.1 813976 D 478434 CDS YP_003030663.1 253797662 8162910 814398..814937 1 NC_012943.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 814937 rplF 8162910 rplF Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L6 YP_003030663.1 814398 D 478434 CDS YP_003030664.1 253797663 8162911 814940..815308 1 NC_012943.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 815308 rplR 8162911 rplR Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L18 YP_003030664.1 814940 D 478434 CDS YP_003030665.1 253797664 8162912 815328..815990 1 NC_012943.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 815990 rpsE 8162912 rpsE Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S5 YP_003030665.1 815328 D 478434 CDS YP_003030666.1 253797665 8162913 815993..816190 1 NC_012943.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 816190 rpmD 8162913 rpmD Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L30 YP_003030666.1 815993 D 478434 CDS YP_003030667.1 253797666 8162914 816190..816630 1 NC_012943.1 late assembly protein; 50S ribosomal protein L15 816630 rplO 8162914 rplO Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L15 YP_003030667.1 816190 D 478434 CDS YP_003030668.1 253797667 8162915 816663..818534 1 NC_012943.1 protease IV sppA 818534 8162915 TBMG_00738 Mycobacterium tuberculosis KZN 1435 protease IV sppA YP_003030668.1 816663 D 478434 CDS YP_003030669.1 253797668 8162916 complement(818531..818905) 1 NC_012943.1 hypothetical protein 818905 8162916 TBMG_03996 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030669.1 818531 R 478434 CDS YP_003030670.1 253797669 8162917 complement(818539..819444) 1 NC_012943.1 hypothetical protein 819444 8162917 TBMG_03997 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030670.1 818539 R 478434 CDS YP_003030671.1 253797670 8162918 complement(819537..820640) 1 NC_012943.1 hypothetical protein 820640 8162918 TBMG_00740 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030671.1 819537 R 478434 CDS YP_003030672.1 253797671 8162919 complement(820843..821499) 1 NC_012943.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose-phosphate aldolase 821499 8162919 TBMG_00741 Mycobacterium tuberculosis KZN 1435 L-fuculose-phosphate aldolase YP_003030672.1 820843 R 478434 CDS YP_003030673.1 253797672 8162920 complement(821496..822476) 1 NC_012943.1 D-3-phosphoglycerate dehydrogenase serA2 822476 8162920 TBMG_00742 Mycobacterium tuberculosis KZN 1435 D-3-phosphoglycerate dehydrogenase serA2 YP_003030673.1 821496 R 478434 CDS YP_003030674.1 253797673 8162921 822507..823853 1 NC_012943.1 D-xylulose kinase xylB 823853 8162921 TBMG_00743 Mycobacterium tuberculosis KZN 1435 D-xylulose kinase xylB YP_003030674.1 822507 D 478434 CDS YP_003030675.1 253797674 8162922 823866..824594 1 NC_012943.1 hypothetical protein 824594 8162922 TBMG_00744 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030675.1 823866 D 478434 CDS YP_003030676.1 253797675 8162923 complement(824683..825639) 1 NC_012943.1 hypothetical protein 825639 8162923 TBMG_00745 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030676.1 824683 R 478434 CDS YP_003030677.1 253797676 8162924 825800..827125 1 NC_012943.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 827125 secY 8162924 secY Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit SecY YP_003030677.1 825800 D 478434 CDS YP_003030678.1 253797677 8162925 827122..827667 1 NC_012943.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 827667 adk 8162925 adk Mycobacterium tuberculosis KZN 1435 adenylate kinase YP_003030678.1 827122 D 478434 CDS YP_003030679.1 253797678 8162926 827670..828470 1 NC_012943.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 828470 8162926 TBMG_00748 Mycobacterium tuberculosis KZN 1435 methionine aminopeptidase YP_003030679.1 827670 D 478434 CDS YP_003030680.1 253797679 8162927 828543..829076 1 NC_012943.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and secreted or membrane proteins; RNA polymerase sigma factor SigL 829076 8162927 TBMG_00749 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigL YP_003030680.1 828543 D 478434 CDS YP_003030681.1 253797680 8162928 829140..829892 1 NC_012943.1 hypothetical protein 829892 8162928 TBMG_00750 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030681.1 829140 D 478434 CDS YP_003030682.1 253797681 8162929 830207..830704 1 NC_012943.1 transcriptional regulator 830704 8162929 TBMG_00751 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030682.1 830207 D 478434 CDS YP_003030683.1 253797682 8162930 831062..831610 1 NC_012943.1 hypothetical protein 831610 8162930 TBMG_00752 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030683.1 831062 D 478434 CDS YP_003030684.1 253797683 8162931 831855..832661 1 NC_012943.1 hypothetical protein 832661 8162931 TBMG_00753 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030684.1 831855 D 478434 CDS YP_003030685.1 253797684 8162932 832695..833303 1 NC_012943.1 hypothetical protein 833303 8162932 TBMG_00754 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030685.1 832695 D 478434 CDS YP_003030686.1 253797685 8162933 833534..833848 1 NC_012943.1 transposase 833848 8162933 TBMG_00755 Mycobacterium tuberculosis KZN 1435 transposase YP_003030686.1 833534 D 478434 CDS YP_003030687.1 253797686 8162934 833990..834508 1 NC_012943.1 PE-PGRS family protein 834508 8162934 TBMG_00756 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030687.1 833990 D 478434 CDS YP_003030688.1 253797687 8162935 complement(834886..835443) 1 NC_012943.1 hypothetical protein 835443 8162935 TBMG_00757 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030688.1 834886 R 478434 CDS YP_003030689.1 253797688 8162936 complement(835440..835946) 1 NC_012943.1 transcriptional regulator 835946 8162936 TBMG_00758 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030689.1 835440 R 478434 CDS YP_003030690.1 253797689 8162937 complement(836059..836205) 1 NC_012943.1 3-hydroxyisobutyrate dehydrogenase 836205 8162937 TBMG_03998 Mycobacterium tuberculosis KZN 1435 3-hydroxyisobutyrate dehydrogenase YP_003030690.1 836059 R 478434 CDS YP_003030691.1 253797690 8162939 836154..836681 1 NC_012943.1 hypothetical protein 836681 8162939 TBMG_00759 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030691.1 836154 D 478434 CDS YP_003030692.1 253797691 8162938 836701..839052 1 NC_012943.1 PE-PGRS family protein 839052 8162938 TBMG_00760 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030692.1 836701 D 478434 CDS YP_003030693.1 253797692 8162940 839451..842054 1 NC_012943.1 hypothetical protein 842054 8162940 TBMG_00761 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030693.1 839451 D 478434 CDS YP_003030694.1 253797693 8162941 842145..842402 1 NC_012943.1 antitoxin 842402 8162941 TBMG_00762 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003030694.1 842145 D 478434 CDS YP_003030695.1 253797694 8162942 842426..842854 1 NC_012943.1 toxin 842854 8162942 TBMG_00763 Mycobacterium tuberculosis KZN 1435 toxin YP_003030695.1 842426 D 478434 CDS YP_003030696.1 253797695 8162943 843207..843476 1 NC_012943.1 hypothetical protein 843476 8162943 TBMG_00764 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030696.1 843207 D 478434 CDS YP_003030697.1 253797696 8162944 complement(843545..844429) 1 NC_012943.1 3-hydroxyisobutyrate dehydrogenase 844429 8162944 TBMG_00765 Mycobacterium tuberculosis KZN 1435 3-hydroxyisobutyrate dehydrogenase YP_003030697.1 843545 R 478434 CDS YP_003030698.1 253797697 8162945 complement(844440..845612) 1 NC_012943.1 acyl-CoA dehydrogenase 845612 8162945 TBMG_00766 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030698.1 844440 R 478434 CDS YP_003030699.1 253797698 8162946 complement(845619..847151) 1 NC_012943.1 methylmalonate-semialdehyde dehydrogenase mmsA 847151 8162946 TBMG_00767 Mycobacterium tuberculosis KZN 1435 methylmalonate-semialdehyde dehydrogenase mmsA YP_003030699.1 845619 R 478434 CDS YP_003030700.1 253797699 8162947 847357..849111 1 NC_012943.1 PE-PGRS family protein 849111 8162947 TBMG_00768 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030700.1 847357 D 478434 CDS YP_003030701.1 253797700 8162948 complement(849301..851241) 1 NC_012943.1 PPE family protein 851241 8162948 TBMG_00769 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030701.1 849301 R 478434 CDS YP_003030702.1 253797701 8162949 complement(851540..851725) 1 NC_012943.1 transposase 851725 8162949 TBMG_00770 Mycobacterium tuberculosis KZN 1435 transposase YP_003030702.1 851540 R 478434 CDS YP_003030703.1 253797702 8162951 complement(851939..852664) 1 NC_012943.1 hypothetical protein 852664 8162951 TBMG_00771 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030703.1 851939 R 478434 CDS YP_003030704.1 253797703 8162952 852806..853549 1 NC_012943.1 two component system transcriptional regulator phoP 853549 8162952 TBMG_00772 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator phoP YP_003030704.1 852806 D 478434 CDS YP_003030705.1 253797704 8162953 853594..855051 1 NC_012943.1 two component system sensor kinase phoR 855051 8162953 TBMG_00773 Mycobacterium tuberculosis KZN 1435 two component system sensor kinase phoR YP_003030705.1 853594 D 478434 CDS YP_003030706.1 253797705 8162954 complement(855023..855424) 1 NC_012943.1 hypothetical protein 855424 8162954 TBMG_00774 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030706.1 855023 R 478434 CDS YP_003030707.1 253797706 8162955 complement(855464..855883) 1 NC_012943.1 hypothetical protein 855883 8162955 TBMG_00775 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030707.1 855464 R 478434 CDS YP_003030708.1 253797707 8162956 complement(855896..857023) 1 NC_012943.1 zinc-type alcohol dehydrogenase NAD dependent adhB 857023 8162956 TBMG_00776 Mycobacterium tuberculosis KZN 1435 zinc-type alcohol dehydrogenase NAD dependent adhB YP_003030708.1 855896 R 478434 CDS YP_003030709.1 253797708 8162957 complement(857122..857667) 1 NC_012943.1 hypothetical protein 857667 8162957 TBMG_00777 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030709.1 857122 R 478434 CDS YP_003030710.1 253797709 8162958 complement(857670..857876) 1 NC_012943.1 ferredoxin 857876 8162958 TBMG_00778 Mycobacterium tuberculosis KZN 1435 ferredoxin YP_003030710.1 857670 R 478434 CDS YP_003030711.1 253797710 8162959 complement(857879..859234) 1 NC_012943.1 cytochrome P450 51 cyp51 859234 8162959 TBMG_00779 Mycobacterium tuberculosis KZN 1435 cytochrome P450 51 cyp51 YP_003030711.1 857879 R 478434 CDS YP_003030712.1 253797711 8162960 complement(859234..860061) 1 NC_012943.1 short chain dehydrogenase 860061 8162960 TBMG_00780 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003030712.1 859234 R 478434 CDS YP_003030713.1 253797712 8162961 complement(860311..861270) 1 NC_012943.1 truncated CDS; cytochrome P450 123 cyp123 861270 8162961 TBMG_00781 Mycobacterium tuberculosis KZN 1435 cytochrome P450 123 cyp123 YP_003030713.1 860311 R 478434 CDS YP_003030714.1 253797713 8162962 complement(861295..861909) 1 NC_012943.1 hypothetical protein 861909 8162962 TBMG_00782 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030714.1 861295 R 478434 CDS YP_003030715.1 253797714 8162963 862111..863580 1 NC_012943.1 aldehyde dehydrogenase 863580 8162963 TBMG_00783 Mycobacterium tuberculosis KZN 1435 aldehyde dehydrogenase YP_003030715.1 862111 D 478434 CDS YP_003030716.1 253797715 8162964 863611..864357 1 NC_012943.1 short chain dehydrogenase 864357 8162964 TBMG_00784 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003030716.1 863611 D 478434 CDS YP_003030717.1 253797716 8162965 864455..865342 1 NC_012943.1 dehydrogenase/reductase 865342 8162965 TBMG_00785 Mycobacterium tuberculosis KZN 1435 dehydrogenase/reductase YP_003030717.1 864455 D 478434 CDS YP_003030718.1 253797717 8162966 865339..865773 1 NC_012943.1 4-carboxymuconolactone decarboxylase 865773 8162966 TBMG_00786 Mycobacterium tuberculosis KZN 1435 4-carboxymuconolactone decarboxylase YP_003030718.1 865339 D 478434 CDS YP_003030719.1 253797718 8162967 865785..867053 1 NC_012943.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 867053 8162967 TBMG_00787 Mycobacterium tuberculosis KZN 1435 phosphoribosylamine--glycine ligase YP_003030719.1 865785 D 478434 CDS YP_003030720.1 253797719 8162968 complement(867050..868588) 1 NC_012943.1 bifunctional acylase ggtA 868588 8162968 TBMG_00788 Mycobacterium tuberculosis KZN 1435 bifunctional acylase ggtA YP_003030720.1 867050 R 478434 CDS YP_003030721.1 253797720 8162969 complement(868639..869550) 1 NC_012943.1 hypothetical protein 869550 8162969 TBMG_00789 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030721.1 868639 R 478434 CDS YP_003030722.1 253797721 8162970 869606..870229 1 NC_012943.1 hypothetical protein 870229 8162970 TBMG_00790 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030722.1 869606 D 478434 CDS YP_003030723.1 253797722 8162971 complement(870183..870962) 1 NC_012943.1 hypothetical protein 870962 8162971 TBMG_00791 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030723.1 870183 R 478434 CDS YP_003030724.1 253797723 8162972 871207..872625 1 NC_012943.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 872625 8162972 TBMG_00792 Mycobacterium tuberculosis KZN 1435 adenylosuccinate lyase YP_003030724.1 871207 D 478434 CDS YP_003030725.1 253797724 8162973 872630..873874 1 NC_012943.1 cytochrome P450 126 cyp126 873874 8162973 TBMG_00793 Mycobacterium tuberculosis KZN 1435 cytochrome P450 126 cyp126 YP_003030725.1 872630 D 478434 CDS YP_003030726.1 253797725 8162974 complement(873871..874554) 1 NC_012943.1 hypothetical protein 874554 8162974 TBMG_00794 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030726.1 873871 R 478434 CDS YP_003030727.1 253797726 8162976 874542..875435 1 NC_012943.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 875435 8162976 TBMG_00795 Mycobacterium tuberculosis KZN 1435 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_003030727.1 874542 D 478434 CDS YP_003030728.1 253797727 8162975 875435..877591 1 NC_012943.1 protease II ptrB 877591 8162975 TBMG_00796 Mycobacterium tuberculosis KZN 1435 protease II ptrB YP_003030728.1 875435 D 478434 CDS YP_003030729.1 253797728 8162977 complement(877520..877912) 1 NC_012943.1 hypothetical protein 877912 8162977 TBMG_00797 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030729.1 877520 R 478434 CDS YP_003030730.1 253797729 8162979 877890..878030 1 NC_012943.1 transcriptional regulator 878030 8162979 TBMG_03999 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030730.1 877890 D 478434 CDS YP_003030731.1 253797730 8162978 complement(878019..879656) 1 NC_012943.1 multidrug resistance membrane efflux protein emrB 879656 8162978 TBMG_00798 Mycobacterium tuberculosis KZN 1435 multidrug resistance membrane efflux protein emrB YP_003030731.1 878019 R 478434 CDS YP_003030732.1 253797731 8162980 879821..880525 1 NC_012943.1 hypothetical protein 880525 8162980 TBMG_00799 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030732.1 879821 D 478434 CDS YP_003030733.1 253797732 8162981 880541..882241 1 NC_012943.1 proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 882241 8162981 TBMG_00800 Mycobacterium tuberculosis KZN 1435 FAD-binding dehydrogenase YP_003030733.1 880541 D 478434 CDS YP_003030734.1 253797733 8162982 complement(882276..882914) 1 NC_012943.1 hypothetical protein 882914 8162982 TBMG_00801 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030734.1 882276 R 478434 CDS YP_003030735.1 253797734 8162984 882660..883619 1 NC_012943.1 hypothetical protein 883619 8162984 TBMG_00802 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030735.1 882660 D 478434 CDS YP_003030736.1 253797735 8162983 883725..883964 1 NC_012943.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS 883964 8162983 TBMG_00803 Mycobacterium tuberculosis KZN 1435 phosphoribosylformylglycinamidine synthase subunit PurS YP_003030736.1 883725 D 478434 CDS YP_003030737.1 253797736 8161042 883961..884635 1 NC_012943.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 884635 8161042 TBMG_00804 Mycobacterium tuberculosis KZN 1435 phosphoribosylformylglycinamidine synthase I YP_003030737.1 883961 D 478434 CDS YP_003030738.1 253797737 8161045 complement(884652..885251) 1 NC_012943.1 hypothetical protein 885251 8161045 TBMG_00805 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030738.1 884652 R 478434 CDS YP_003030739.1 253797738 8161046 complement(885273..886001) 1 NC_012943.1 hypothetical protein 886001 8161046 TBMG_00806 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030739.1 885273 R 478434 CDS YP_003030740.1 253797739 8161047 complement(885998..887041) 1 NC_012943.1 hypothetical protein 887041 8161047 TBMG_00807 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030740.1 885998 R 478434 CDS YP_003030741.1 253797740 8161048 complement(887038..887847) 1 NC_012943.1 GntR family transcriptional regulator 887847 8161048 TBMG_00808 Mycobacterium tuberculosis KZN 1435 GntR family transcriptional regulator YP_003030741.1 887038 R 478434 CDS YP_003030742.1 253797741 8161049 887920..888225 1 NC_012943.1 hypothetical protein 888225 8161049 TBMG_00809 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030742.1 887920 D 478434 CDS YP_003030743.1 253797742 8161050 complement(888338..889837) 1 NC_012943.1 oxidoreductase 889837 8161050 TBMG_00810 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030743.1 888338 R 478434 CDS YP_003030744.1 253797743 8161051 890173..890391 1 NC_012943.1 transposase 890391 8161051 TBMG_04000 Mycobacterium tuberculosis KZN 1435 transposase YP_003030744.1 890173 D 478434 CDS YP_003030745.1 253797744 8161052 890413..891324 1 NC_012943.1 transposase 891324 8161052 TBMG_00811 Mycobacterium tuberculosis KZN 1435 transposase YP_003030745.1 890413 D 478434 CDS YP_003030746.1 253797745 8161053 complement(891314..892111) 1 NC_012943.1 hypothetical protein 892111 8161053 TBMG_00812 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030746.1 891314 R 478434 CDS YP_003030747.1 253797746 8161054 complement(892108..893115) 1 NC_012943.1 hypothetical protein 893115 8161054 TBMG_00813 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030747.1 892108 R 478434 CDS YP_003030748.1 253797747 8161055 893160..894461 1 NC_012943.1 catalyzes the removal of amino acids from the N termini of peptides; aminopeptidase 2 894461 8161055 TBMG_00814 Mycobacterium tuberculosis KZN 1435 aminopeptidase 2 YP_003030748.1 893160 D 478434 CDS YP_003030749.1 253797748 8161056 894473..894820 1 NC_012943.1 hypothetical protein 894820 8161056 TBMG_00815 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030749.1 894473 D 478434 CDS YP_003030750.1 253797749 8161057 complement(894814..895470) 1 NC_012943.1 hypothetical protein 895470 8161057 TBMG_00816 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030750.1 894814 R 478434 CDS YP_003030751.1 253797750 8161058 895662..897926 1 NC_012943.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 897926 8161058 TBMG_00817 Mycobacterium tuberculosis KZN 1435 phosphoribosylformylglycinamidine synthase II YP_003030751.1 895662 D 478434 CDS YP_003030752.1 253797751 8161059 897923..898552 1 NC_012943.1 hypothetical protein 898552 8161059 TBMG_00818 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030752.1 897923 D 478434 CDS YP_003030753.1 253797752 8161060 898673..899629 1 NC_012943.1 hypothetical protein 899629 8161060 TBMG_00819 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030753.1 898673 D 478434 CDS YP_003030754.1 253797753 8161061 complement(899574..901172) 1 NC_012943.1 UDP-glucose-4-epimerase cpsY 901172 8161061 TBMG_00820 Mycobacterium tuberculosis KZN 1435 UDP-glucose-4-epimerase cpsY YP_003030754.1 899574 R 478434 CDS YP_003030755.1 253797754 8161062 901477..901866 1 NC_012943.1 hypothetical protein 901866 8161062 TBMG_00821 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030755.1 901477 D 478434 CDS YP_003030756.1 253797755 8161063 901953..903536 1 NC_012943.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 903536 8161063 TBMG_00822 Mycobacterium tuberculosis KZN 1435 amidophosphoribosyltransferase YP_003030756.1 901953 D 478434 CDS YP_003030757.1 253797756 8161064 903567..904661 1 NC_012943.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 904661 8161064 TBMG_00823 Mycobacterium tuberculosis KZN 1435 phosphoribosylaminoimidazole synthetase YP_003030757.1 903567 D 478434 CDS YP_003030758.1 253797757 8161065 complement(904747..904929) 1 NC_012943.1 hypothetical protein 904929 8161065 TBMG_00824 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030758.1 904747 R 478434 CDS YP_003030759.1 253797758 8161066 complement(905076..906182) 1 NC_012943.1 hypothetical protein 906182 8161066 TBMG_00825 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030759.1 905076 R 478434 CDS YP_003030760.1 253797759 8161067 906247..907134 1 NC_012943.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 907134 8161067 TBMG_00826 Mycobacterium tuberculosis KZN 1435 4-amino-4-deoxychorismate lyase YP_003030760.1 906247 D 478434 CDS YP_003030761.1 253797760 8161068 complement(907180..907860) 1 NC_012943.1 hypothetical protein 907860 8161068 TBMG_00827 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030761.1 907180 R 478434 CDS YP_003030762.1 253797761 8161069 complement(908023..908325) 1 NC_012943.1 hypothetical protein 908325 8161069 TBMG_00828 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030762.1 908023 R 478434 CDS YP_003030763.1 253797762 8161070 complement(908327..909160) 1 NC_012943.1 thiosulfate sulfurtransferase cysA2 909160 8161070 TBMG_00829 Mycobacterium tuberculosis KZN 1435 thiosulfate sulfurtransferase cysA2 YP_003030763.1 908327 R 478434 CDS YP_003030764.1 253797763 8161071 complement(909453..909875) 1 NC_012943.1 thioredoxin thiX 909875 8161071 TBMG_00830 Mycobacterium tuberculosis KZN 1435 thioredoxin thiX YP_003030764.1 909453 R 478434 CDS YP_003030765.1 253797764 8161072 complement(909872..910684) 1 NC_012943.1 hypothetical protein 910684 8161072 TBMG_00831 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030765.1 909872 R 478434 CDS YP_003030766.1 253797765 8161073 910814..911581 1 NC_012943.1 transcriptional regulator 911581 8161073 TBMG_00832 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030766.1 910814 D 478434 CDS YP_003030767.1 253797766 8161074 911578..912525 1 NC_012943.1 mycothiol biosynthesis acetyltransferase 912525 8161074 TBMG_00833 Mycobacterium tuberculosis KZN 1435 mycothiol biosynthesis acetyltransferase YP_003030767.1 911578 D 478434 CDS YP_003030768.1 253797767 8161075 912568..913344 1 NC_012943.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 913344 8161075 TBMG_00834 Mycobacterium tuberculosis KZN 1435 phosphate transporter ATP-binding protein YP_003030768.1 912568 D 478434 CDS YP_003030769.1 253797768 8161076 complement(913400..914041) 1 NC_012943.1 phosphate-transport system transcriptional regulator phoY2 914041 8161076 TBMG_00835 Mycobacterium tuberculosis KZN 1435 phosphate-transport system transcriptional regulator phoY2 YP_003030769.1 913400 R 478434 CDS YP_003030770.1 253797769 8161077 complement(914099..916153) 1 NC_012943.1 hypothetical protein 916153 8161077 TBMG_00836 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030770.1 914099 R 478434 CDS YP_003030771.1 253797770 8161078 complement(916319..917488) 1 NC_012943.1 transcriptional regulator 917488 8161078 TBMG_00837 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030771.1 916319 R 478434 CDS YP_003030772.1 253797771 8161079 complement(917576..918592) 1 NC_012943.1 acyl-ACP desaturase 918592 8161079 TBMG_00838 Mycobacterium tuberculosis KZN 1435 acyl-ACP desaturase YP_003030772.1 917576 R 478434 CDS YP_003030773.1 253797772 8161080 complement(918754..919413) 1 NC_012943.1 hypothetical protein 919413 8161080 TBMG_00839 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030773.1 918754 R 478434 CDS YP_003030774.1 253797773 8161081 919476..920531 1 NC_012943.1 hypothetical protein 920531 8161081 TBMG_00840 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030774.1 919476 D 478434 CDS YP_003030775.1 253797774 8161082 complement(920583..920975) 1 NC_012943.1 transcriptional regulator 920975 8161082 TBMG_00841 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030775.1 920583 R 478434 CDS YP_003030776.1 253797775 8161083 complement(921033..921455) 1 NC_012943.1 deaminase 921455 8161083 TBMG_00842 Mycobacterium tuberculosis KZN 1435 deaminase YP_003030776.1 921033 R 478434 CDS YP_003030777.1 253797776 8161085 921417..921707 1 NC_012943.1 transposase 921707 8161085 TBMG_00843 Mycobacterium tuberculosis KZN 1435 transposase YP_003030777.1 921417 D 478434 CDS YP_003030778.1 253797777 8161084 921812..922717 1 NC_012943.1 hypothetical protein 922717 8161084 TBMG_00844 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030778.1 921812 D 478434 CDS YP_003030779.1 253797778 8161086 complement(922736..923551) 1 NC_012943.1 hypothetical protein 923551 8161086 TBMG_00845 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030779.1 922736 R 478434 CDS YP_003030780.1 253797779 8161091 924793..925206 1 NC_012943.1 PE-PGRS family protein 925206 8161091 TBMG_00846 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030780.1 924793 D 478434 CDS YP_003030781.1 253797780 8161092 925203..927452 1 NC_012943.1 PE-PGRS family protein 927452 8161092 TBMG_00847 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030781.1 925203 D 478434 CDS YP_003030782.1 253797781 8161093 complement(927679..930327) 1 NC_012943.1 PE-PGRS family protein 930327 8161093 TBMG_00848 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030782.1 927679 R 478434 CDS YP_003030783.1 253797782 8161094 930795..931439 1 NC_012943.1 hypothetical protein 931439 8161094 TBMG_00849 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030783.1 930795 D 478434 CDS YP_003030784.1 253797783 8161095 complement(931420..931971) 1 NC_012943.1 hypothetical protein 931971 8161095 TBMG_00850 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030784.1 931420 R 478434 CDS YP_003030785.1 253797784 8161096 complement(932089..932973) 1 NC_012943.1 transposase 932973 8161096 TBMG_00851 Mycobacterium tuberculosis KZN 1435 transposase YP_003030785.1 932089 R 478434 CDS YP_003030786.1 253797785 8161097 complement(933024..933350) 1 NC_012943.1 transposase 933350 8161097 TBMG_00852 Mycobacterium tuberculosis KZN 1435 transposase YP_003030786.1 933024 R 478434 CDS YP_003030787.1 253797786 8161098 complement(933399..933701) 1 NC_012943.1 HAD superfamily hydrolase 933701 8161098 TBMG_00853 Mycobacterium tuberculosis KZN 1435 HAD superfamily hydrolase YP_003030787.1 933399 R 478434 CDS YP_003030788.1 253797787 8161099 complement(933824..934075) 1 NC_012943.1 molybdenum cofactor biosynthesis protein D moaD1 934075 8161099 TBMG_00854 Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein D moaD1 YP_003030788.1 933824 R 478434 CDS YP_003030789.1 253797788 8161100 complement(934092..934604) 1 NC_012943.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 934604 moaC 8161100 moaC Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein MoaC YP_003030789.1 934092 R 478434 CDS YP_003030790.1 253797789 8161101 complement(934601..934996) 1 NC_012943.1 pterin-4-alpha-carbinolamine dehydratase 934996 8161101 TBMG_00856 Mycobacterium tuberculosis KZN 1435 pterin-4-alpha-carbinolamine dehydratase YP_003030790.1 934601 R 478434 CDS YP_003030791.1 253797790 8161102 complement(935047..936126) 1 NC_012943.1 molybdenum cofactor biosynthesis protein A moaA1 936126 8161102 TBMG_00857 Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein A moaA1 YP_003030791.1 935047 R 478434 CDS YP_003030792.1 253797791 8161103 complement(936275..936715) 1 NC_012943.1 hypothetical protein 936715 8161103 TBMG_00858 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030792.1 936275 R 478434 CDS YP_003030793.1 253797792 8161104 936814..938397 1 NC_012943.1 alkyldihydroxyacetonephosphate synthase agpS 938397 8161104 TBMG_00859 Mycobacterium tuberculosis KZN 1435 alkyldihydroxyacetonephosphate synthase agpS YP_003030793.1 936814 D 478434 CDS YP_003030794.1 253797793 8161105 complement(938398..939768) 1 NC_012943.1 NADPH:adrenodoxin oxidoreductase fprA 939768 8161105 TBMG_00860 Mycobacterium tuberculosis KZN 1435 NADPH:adrenodoxin oxidoreductase fprA YP_003030794.1 938398 R 478434 CDS YP_003030795.1 253797794 8161106 939872..941008 1 NC_012943.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 941008 prfB 8161106 prfB Mycobacterium tuberculosis KZN 1435 peptide chain release factor 2 YP_003030795.1 939872 D 478434 CDS YP_003030796.1 253797795 8161107 940998..941924 1 NC_012943.1 hypothetical protein 941924 8161107 TBMG_00862 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030796.1 940998 D 478434 CDS YP_003030797.1 253797796 8161108 941887..942363 1 NC_012943.1 hypothetical protein 942363 8161108 TBMG_00863 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030797.1 941887 D 478434 CDS YP_003030798.1 253797797 8161109 942407..943096 1 NC_012943.1 cell division ATP-binding protein ftsE 943096 8161109 TBMG_00864 Mycobacterium tuberculosis KZN 1435 cell division ATP-binding protein ftsE YP_003030798.1 942407 D 478434 CDS YP_003030799.1 253797798 8161110 943097..943990 1 NC_012943.1 cell division protein ftsX 943990 8161110 TBMG_00865 Mycobacterium tuberculosis KZN 1435 cell division protein ftsX YP_003030799.1 943097 D 478434 CDS YP_003030800.1 253797799 8161111 943993..944475 1 NC_012943.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 944475 smpB 8161111 smpB Mycobacterium tuberculosis KZN 1435 SsrA-binding protein YP_003030800.1 943993 D 478434 CDS YP_003030801.1 253797800 8161112 944512..945363 1 NC_012943.1 hypothetical protein 945363 8161112 TBMG_00867 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030801.1 944512 D 478434 CDS YP_003030802.1 253797801 8161113 complement(945850..946170) 1 NC_012943.1 hypothetical protein 946170 8161113 TBMG_00868 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030802.1 945850 R 478434 CDS YP_003030803.1 253797802 8161115 946114..946566 1 NC_012943.1 hypothetical protein 946566 8161115 TBMG_00869 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030803.1 946114 D 478434 CDS YP_003030804.1 253797803 8161114 946685..947998 1 NC_012943.1 PE-PGRS family protein 947998 8161114 TBMG_00870 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003030804.1 946685 D 478434 CDS YP_003030805.1 253797804 8161116 complement(948090..949229) 1 NC_012943.1 hypothetical protein 949229 8161116 TBMG_00871 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030805.1 948090 R 478434 CDS YP_003030806.1 253797805 8161117 complement(949327..949803) 1 NC_012943.1 transcriptional regulator 949803 8161117 TBMG_00872 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030806.1 949327 R 478434 CDS YP_003030807.1 253797806 8161118 949885..951015 1 NC_012943.1 hypothetical protein 951015 8161118 TBMG_00873 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030807.1 949885 D 478434 CDS YP_003030808.1 253797807 8161119 951012..952016 1 NC_012943.1 oxidoreductase 952016 8161119 TBMG_00874 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030808.1 951012 D 478434 CDS YP_003030809.1 253797808 8161120 952042..952962 1 NC_012943.1 hypothetical protein 952962 8161120 TBMG_00875 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030809.1 952042 D 478434 CDS YP_003030810.1 253797809 8161121 complement(952969..954660) 1 NC_012943.1 hypothetical protein 954660 8161121 TBMG_00876 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030810.1 952969 R 478434 CDS YP_003030811.1 253797810 8161122 complement(954678..955565) 1 NC_012943.1 hypothetical protein 955565 8161122 TBMG_00877 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030811.1 954678 R 478434 CDS YP_003030812.1 253797811 8161123 complement(956504..958015) 1 NC_012943.1 fatty-acid-CoA ligase fadD13 958015 8161123 TBMG_00878 Mycobacterium tuberculosis KZN 1435 fatty-acid-CoA ligase fadD13 YP_003030812.1 956504 R 478434 CDS YP_003030813.1 253797812 8161124 complement(958012..959436) 1 NC_012943.1 hypothetical protein 959436 8161124 TBMG_00879 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030813.1 958012 R 478434 CDS YP_003030814.1 253797813 8161125 complement(959433..960854) 1 NC_012943.1 hypothetical protein 960854 8161125 TBMG_00880 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030814.1 959433 R 478434 CDS YP_003030815.1 253797814 8161043 complement(960889..961995) 1 NC_012943.1 zinc-type alcohol dehydrogenase adhD 961995 8161043 TBMG_00881 Mycobacterium tuberculosis KZN 1435 zinc-type alcohol dehydrogenase adhD YP_003030815.1 960889 R 478434 CDS YP_003030816.1 253797815 8161044 complement(962026..962856) 1 NC_012943.1 short-chain type dehydrogenase/reductase 962856 8161044 TBMG_00882 Mycobacterium tuberculosis KZN 1435 short-chain type dehydrogenase/reductase YP_003030816.1 962026 R 478434 CDS YP_003030817.1 253797816 8163918 complement(962853..963779) 1 NC_012943.1 acetyl-hydrolase/esterase lipR 963779 8163918 TBMG_00883 Mycobacterium tuberculosis KZN 1435 acetyl-hydrolase/esterase lipR YP_003030817.1 962853 R 478434 CDS YP_003030818.1 253797817 8163919 complement(963785..965272) 1 NC_012943.1 monooxygenase 965272 8163919 TBMG_00884 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003030818.1 963785 R 478434 CDS YP_003030819.1 253797818 8163920 965347..966372 1 NC_012943.1 AraC family transcriptional regulator 966372 8163920 TBMG_00885 Mycobacterium tuberculosis KZN 1435 AraC family transcriptional regulator YP_003030819.1 965347 D 478434 CDS YP_003030820.1 253797819 8163921 complement(966498..967736) 1 NC_012943.1 hypothetical protein 967736 8163921 TBMG_00886 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030820.1 966498 R 478434 CDS YP_003030821.1 253797820 8163922 967788..971120 1 NC_012943.1 serine/threonine-protein kinase transcriptional regulator pknK 971120 8163922 TBMG_00887 Mycobacterium tuberculosis KZN 1435 serine/threonine-protein kinase transcriptional regulator pknK YP_003030821.1 967788 D 478434 CDS YP_003030822.1 253797821 8163923 971179..972006 1 NC_012943.1 hypothetical protein 972006 8163923 TBMG_00888 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030822.1 971179 D 478434 CDS YP_003030823.1 253797822 8163924 complement(972022..972423) 1 NC_012943.1 hydroxylaminobenzene mutase hab 972423 8163924 TBMG_00889 Mycobacterium tuberculosis KZN 1435 hydroxylaminobenzene mutase hab YP_003030823.1 972022 R 478434 CDS YP_003030824.1 253797823 8163925 complement(972424..974235) 1 NC_012943.1 hydrolase 974235 8163925 TBMG_00890 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003030824.1 972424 R 478434 CDS YP_003030825.1 253797824 8163926 complement(974228..974704) 1 NC_012943.1 hypothetical protein 974704 8163926 TBMG_00891 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030825.1 974228 R 478434 CDS YP_003030826.1 253797825 8163927 974803..975726 1 NC_012943.1 hypothetical protein 975726 8163927 TBMG_00892 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030826.1 974803 D 478434 CDS YP_003030827.1 253797826 8163928 complement(975723..976997) 1 NC_012943.1 hypothetical protein 976997 8163928 TBMG_00893 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030827.1 975723 R 478434 CDS YP_003030828.1 253797827 8163929 977091..977447 1 NC_012943.1 hypothetical protein 977447 8163929 TBMG_00894 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030828.1 977091 D 478434 CDS YP_003030829.1 253797828 8163930 977454..977978 1 NC_012943.1 hypothetical protein 977978 8163930 TBMG_00895 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030829.1 977454 D 478434 CDS YP_003030830.1 253797829 8163931 complement(978203..979312) 1 NC_012943.1 hypothetical protein 979312 8163931 TBMG_00896 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030830.1 978203 R 478434 CDS YP_003030831.1 253797830 8163932 complement(979309..979689) 1 NC_012943.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 979689 8163932 TBMG_00897 Mycobacterium tuberculosis KZN 1435 camphor resistance protein CrcB YP_003030831.1 979309 R 478434 CDS YP_003030832.1 253797831 8163933 complement(979686..980084) 1 NC_012943.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 980084 8163933 TBMG_00898 Mycobacterium tuberculosis KZN 1435 camphor resistance protein CrcB YP_003030832.1 979686 R 478434 CDS YP_003030833.1 253797832 8163934 980154..981797 1 NC_012943.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 981797 8163934 TBMG_00899 Mycobacterium tuberculosis KZN 1435 phosphoglucomutase YP_003030833.1 980154 D 478434 CDS YP_003030834.1 253797833 8163936 complement(981938..982348) 1 NC_012943.1 hypothetical protein 982348 8163936 TBMG_00900 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030834.1 981938 R 478434 CDS YP_003030835.1 253797834 8163937 complement(982461..983069) 1 NC_012943.1 transcriptional regulator, deoR-family 983069 8163937 TBMG_00901 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, deoR-family YP_003030835.1 982461 R 478434 CDS YP_003030836.1 253797835 8163938 complement(983066..983389) 1 NC_012943.1 hypothetical protein 983389 8163938 TBMG_00902 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030836.1 983066 R 478434 CDS YP_003030837.1 253797836 8163939 983526..983951 1 NC_012943.1 hypothetical protein 983951 8163939 TBMG_00903 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030837.1 983526 D 478434 CDS YP_003030838.1 253797837 8163940 complement(984257..986539) 1 NC_012943.1 carbon starvation protein A cstA 986539 8163940 TBMG_00904 Mycobacterium tuberculosis KZN 1435 carbon starvation protein A cstA YP_003030838.1 984257 R 478434 CDS YP_003030839.1 253797838 8163941 complement(986669..988192) 1 NC_012943.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase 988192 ligB 8163941 ligB Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA ligase YP_003030839.1 986669 R 478434 CDS YP_003030840.1 253797839 8163942 988349..988639 1 NC_012943.1 acyl-CoA dehydrogenase 988639 8163942 TBMG_04001 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030840.1 988349 D 478434 CDS YP_003030841.1 253797840 8163943 988659..990461 1 NC_012943.1 acyl-CoA dehydrogenase 990461 8163943 TBMG_00906 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003030841.1 988659 D 478434 CDS YP_003030842.1 253797841 8163944 990578..992050 1 NC_012943.1 GntR family transcriptional regulator 992050 8163944 TBMG_00907 Mycobacterium tuberculosis KZN 1435 GntR family transcriptional regulator YP_003030842.1 990578 D 478434 CDS YP_003030843.1 253797842 8163945 complement(992821..994299) 1 NC_012943.1 cytochrome P450 136 cyp136 994299 8163945 TBMG_00908 Mycobacterium tuberculosis KZN 1435 cytochrome P450 136 cyp136 YP_003030843.1 992821 R 478434 CDS YP_003030844.1 253797843 8163946 994385..995065 1 NC_012943.1 TetR family transcriptional regulator 995065 8163946 TBMG_00909 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030844.1 994385 D 478434 CDS YP_003030845.1 253797844 8163947 995129..995992 1 NC_012943.1 short chain dehydrogenase 995992 8163947 TBMG_00910 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003030845.1 995129 D 478434 CDS YP_003030846.1 253797845 8163948 complement(996046..997086) 1 NC_012943.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 997086 8163948 TBMG_00911 Mycobacterium tuberculosis KZN 1435 DNA polymerase IV YP_003030846.1 996046 R 478434 CDS YP_003030847.1 253797846 8163949 complement(997096..997710) 1 NC_012943.1 TetR family transcriptional regulator 997710 8163949 TBMG_00912 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003030847.1 997096 R 478434 CDS YP_003030848.1 253797847 8163950 997802..998356 1 NC_012943.1 hypothetical protein 998356 8163950 TBMG_00913 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030848.1 997802 D 478434 CDS YP_003030849.1 253797848 8163951 998437..998841 1 NC_012943.1 hypothetical protein 998841 8163951 TBMG_00914 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030849.1 998437 D 478434 CDS YP_003030850.1 253797849 8163952 998819..999058 1 NC_012943.1 glutaredoxin-like electron transporter nrdH 999058 8163952 TBMG_00915 Mycobacterium tuberculosis KZN 1435 glutaredoxin-like electron transporter nrdH YP_003030850.1 998819 D 478434 CDS YP_003030851.1 253797850 8163953 999093..999545 1 NC_012943.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 999545 nrdI 8163953 nrdI Mycobacterium tuberculosis KZN 1435 ribonucleotide reductase stimulatory protein YP_003030851.1 999093 D 478434 CDS YP_003030852.1 253797851 8163954 999515..1001692 1 NC_012943.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1001692 8163954 TBMG_00917 Mycobacterium tuberculosis KZN 1435 ribonucleotide-diphosphate reductase subunit alpha YP_003030852.1 999515 D 478434 CDS YP_003030853.1 253797852 8163955 1001820..1002560 1 NC_012943.1 transcriptional regulator, asnC-family 1002560 8163955 TBMG_00918 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, asnC-family YP_003030853.1 1001820 D 478434 CDS YP_003030854.1 253797853 8163956 1002694..1004268 1 NC_012943.1 monooxygenase 1004268 8163956 TBMG_00919 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003030854.1 1002694 D 478434 CDS YP_003030855.1 253797854 8163957 1004399..1005373 1 NC_012943.1 ribonucleotide-diphosphate reductase subunit beta 1005373 nrdF2 8163957 nrdF2 Mycobacterium tuberculosis KZN 1435 ribonucleotide-diphosphate reductase subunit beta YP_003030855.1 1004399 D 478434 CDS YP_003030856.1 253797855 8163958 1005471..1005755 1 NC_012943.1 hypothetical protein 1005755 8163958 TBMG_00921 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030856.1 1005471 D 478434 CDS YP_003030857.1 253797856 8163959 1006089..1006463 1 NC_012943.1 hypothetical protein 1006463 8163959 TBMG_00922 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030857.1 1006089 D 478434 CDS YP_003030858.1 253797857 8163960 complement(1006452..1007492) 1 NC_012943.1 NADP-dependent alcohol dehydrogenase adhC 1007492 8163960 TBMG_00923 Mycobacterium tuberculosis KZN 1435 NADP-dependent alcohol dehydrogenase adhC YP_003030858.1 1006452 R 478434 CDS YP_003030859.1 253797858 8163961 complement(1007562..1008641) 1 NC_012943.1 Fe(III)-dicitrate-binding periplasmic lipoprotein fecB 1008641 8163961 TBMG_04002 Mycobacterium tuberculosis KZN 1435 Fe(III)-dicitrate-binding periplasmic lipoprotein fecB YP_003030859.1 1007562 R 478434 CDS YP_003030860.1 253797859 8163962 1008856..1010577 1 NC_012943.1 cytochrome C oxidase polypeptide I ctaD 1010577 8163962 TBMG_00926 Mycobacterium tuberculosis KZN 1435 cytochrome C oxidase polypeptide I ctaD YP_003030860.1 1008856 D 478434 CDS YP_003030861.1 253797860 8163963 1010615..1011844 1 NC_012943.1 phosphoserine phosphatase serB2 1011844 8163963 TBMG_00927 Mycobacterium tuberculosis KZN 1435 phosphoserine phosphatase serB2 YP_003030861.1 1010615 D 478434 CDS YP_003030862.1 253797861 8163964 1011859..1012722 1 NC_012943.1 ABC transporter ATP-binding protein 1012722 8163964 TBMG_00928 Mycobacterium tuberculosis KZN 1435 ABC transporter ATP-binding protein YP_003030862.1 1011859 D 478434 CDS YP_003030863.1 253797862 8163965 1012719..1013585 1 NC_012943.1 hypothetical protein 1013585 8163965 TBMG_00929 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030863.1 1012719 D 478434 CDS YP_003030864.1 253797863 8163966 1013573..1014358 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1014358 8163966 TBMG_00930 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003030864.1 1013573 D 478434 CDS YP_003030865.1 253797864 8163967 1014369..1015352 1 NC_012943.1 hypothetical protein 1015352 8163967 TBMG_00931 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030865.1 1014369 D 478434 CDS YP_003030866.1 253797865 8163968 1015487..1016563 1 NC_012943.1 hypothetical protein 1016563 8163968 TBMG_00932 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030866.1 1015487 D 478434 CDS YP_003030867.1 253797866 8163969 1016636..1017319 1 NC_012943.1 hypothetical protein 1017319 8163969 TBMG_00933 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030867.1 1016636 D 478434 CDS YP_003030868.1 253797867 8163970 complement(1017316..1018398) 1 NC_012943.1 hypothetical protein 1018398 8163970 TBMG_00934 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030868.1 1017316 R 478434 CDS YP_003030869.1 253797868 8163971 1018904..1019758 1 NC_012943.1 transferase 1019758 8163971 TBMG_00935 Mycobacterium tuberculosis KZN 1435 transferase YP_003030869.1 1018904 D 478434 CDS YP_003030870.1 253797869 8163972 complement(1019849..1020397) 1 NC_012943.1 hypothetical protein 1020397 8163972 TBMG_00936 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030870.1 1019849 R 478434 CDS YP_003030871.1 253797870 8163973 complement(1020576..1020965) 1 NC_012943.1 hypothetical protein 1020965 8163973 TBMG_04003 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030871.1 1020576 R 478434 CDS YP_003030872.1 253797871 8163974 complement(1020962..1022230) 1 NC_012943.1 transferase 1022230 8163974 TBMG_00937 Mycobacterium tuberculosis KZN 1435 transferase YP_003030872.1 1020962 R 478434 CDS YP_003030873.1 253797872 8163975 complement(1022274..1023854) 1 NC_012943.1 hypothetical protein 1023854 8163975 TBMG_00938 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030873.1 1022274 R 478434 CDS YP_003030874.1 253797873 8163976 complement(1023851..1024675) 1 NC_012943.1 hypothetical protein 1024675 8163976 TBMG_00939 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030874.1 1023851 R 478434 CDS YP_003030875.1 253797874 8163977 1024906..1025706 1 NC_012943.1 electron transfer flavoprotein beta subunit fixA 1025706 8163977 TBMG_00940 Mycobacterium tuberculosis KZN 1435 electron transfer flavoprotein beta subunit fixA YP_003030875.1 1024906 D 478434 CDS YP_003030876.1 253797875 8163978 1025745..1026701 1 NC_012943.1 electron transfer flavoprotein alpha subunit fixB 1026701 8163978 TBMG_00941 Mycobacterium tuberculosis KZN 1435 electron transfer flavoprotein alpha subunit fixB YP_003030876.1 1025745 D 478434 CDS YP_003030877.1 253797876 8163979 1026857..1027702 1 NC_012943.1 hypothetical protein 1027702 8163979 TBMG_00942 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030877.1 1026857 D 478434 CDS YP_003030878.1 253797877 8163980 1027699..1028613 1 NC_012943.1 hypothetical protein 1028613 8163980 TBMG_00943 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030878.1 1027699 D 478434 CDS YP_003030879.1 253797878 8163981 1028710..1029891 1 NC_012943.1 cysteine desulfurase iscS 1029891 8163981 TBMG_00944 Mycobacterium tuberculosis KZN 1435 cysteine desulfurase iscS YP_003030879.1 1028710 D 478434 CDS YP_003030880.1 253797879 8163982 1029888..1030991 1 NC_012943.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1030991 mnmA 8163982 mnmA Mycobacterium tuberculosis KZN 1435 tRNA-specific 2-thiouridylase MnmA YP_003030880.1 1029888 D 478434 CDS YP_003030881.1 253797880 8163983 1031091..1032401 1 NC_012943.1 transposase 1032401 8163983 TBMG_00946 Mycobacterium tuberculosis KZN 1435 transposase YP_003030881.1 1031091 D 478434 CDS YP_003030882.1 253797881 8163984 1032783..1033097 1 NC_012943.1 PE family protein 1033097 8163984 TBMG_00947 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003030882.1 1032783 D 478434 CDS YP_003030883.1 253797882 8163985 1033094..1034401 1 NC_012943.1 PPE family protein 1034401 8163985 TBMG_00948 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030883.1 1033094 D 478434 CDS YP_003030884.1 253797883 8163986 1034433..1034741 1 NC_012943.1 esat-6 like protein esxS 1034741 8163986 TBMG_00949 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxS YP_003030884.1 1034433 D 478434 CDS YP_003030885.1 253797884 8163987 1034776..1035066 1 NC_012943.1 esat-6 like protein esxR 1035066 8163987 TBMG_00950 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxR YP_003030885.1 1034776 D 478434 CDS YP_003030886.1 253797885 8163988 1035106..1035282 1 NC_012943.1 hypothetical protein 1035282 8163988 TBMG_04004 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030886.1 1035106 D 478434 CDS YP_003030887.1 253797886 8163989 1035275..1035448 1 NC_012943.1 hypothetical protein 1035448 8163989 TBMG_04005 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030887.1 1035275 D 478434 CDS YP_003030888.1 253797887 8163990 1035534..1036838 1 NC_012943.1 PPE family protein 1036838 8163990 TBMG_00952 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003030888.1 1035534 D 478434 CDS YP_003030889.1 253797888 8163991 1036922..1037287 1 NC_012943.1 esat-6 like protein esxQ 1037287 8163991 TBMG_00953 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxQ YP_003030889.1 1036922 D 478434 CDS YP_003030890.1 253797889 8163992 complement(1037390..1038019) 1 NC_012943.1 hypothetical protein 1038019 8163992 TBMG_00954 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030890.1 1037390 R 478434 CDS YP_003030891.1 253797890 8163993 1038113..1039126 1 NC_012943.1 hypothetical protein 1039126 8163993 TBMG_00955 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030891.1 1038113 D 478434 CDS YP_003030892.1 253797891 8163994 1039810..1041234 1 NC_012943.1 truncated CDS; NAD-dependent DNA ligase ligA 1041234 8163994 TBMG_00956 Mycobacterium tuberculosis KZN 1435 NAD-dependent DNA ligase ligA YP_003030892.1 1039810 D 478434 CDS YP_003030893.1 253797892 8163995 complement(1041308..1042030) 1 NC_012943.1 hypothetical protein 1042030 8163995 TBMG_00957 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030893.1 1041308 R 478434 CDS YP_003030894.1 253797893 8163996 1042049..1042348 1 NC_012943.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1042348 gatC 8163996 gatC Mycobacterium tuberculosis KZN 1435 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_003030894.1 1042049 D 478434 CDS YP_003030895.1 253797894 8163997 1042345..1043829 1 NC_012943.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1043829 gatA 8163997 gatA Mycobacterium tuberculosis KZN 1435 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_003030895.1 1042345 D 478434 CDS YP_003030896.1 253797895 8163998 1043925..1044956 1 NC_012943.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1044956 8163998 TBMG_00960 Mycobacterium tuberculosis KZN 1435 6-phosphofructokinase YP_003030896.1 1043925 D 478434 CDS YP_003030897.1 253797896 8163999 1044986..1046515 1 NC_012943.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1046515 gatB 8163999 gatB Mycobacterium tuberculosis KZN 1435 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_003030897.1 1044986 D 478434 CDS YP_003030898.1 253797897 8162246 complement(1046512..1047135) 1 NC_012943.1 hypothetical protein 1047135 8162246 TBMG_00962 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030898.1 1046512 R 478434 CDS YP_003030899.1 253797898 8162251 1047329..1047943 1 NC_012943.1 oxidoreductase 1047943 8162251 TBMG_00963 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030899.1 1047329 D 478434 CDS YP_003030900.1 253797899 8162252 complement(1047949..1049133) 1 NC_012943.1 hypothetical protein 1049133 8162252 TBMG_00964 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030900.1 1047949 R 478434 CDS YP_003030901.1 253797900 8162253 1049247..1050086 1 NC_012943.1 hypothetical protein 1050086 8162253 TBMG_00965 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030901.1 1049247 D 478434 CDS YP_003030902.1 253797901 8162254 complement(1050093..1050431) 1 NC_012943.1 low molecular weight protein antigen 6 cfp6 1050431 8162254 TBMG_00966 Mycobacterium tuberculosis KZN 1435 low molecular weight protein antigen 6 cfp6 YP_003030902.1 1050093 R 478434 CDS YP_003030903.1 253797902 8162255 1050793..1052649 1 NC_012943.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit 1052649 8162255 TBMG_00967 Mycobacterium tuberculosis KZN 1435 acetolactate synthase 1 catalytic subunit YP_003030903.1 1050793 D 478434 CDS YP_003030904.1 253797903 8162256 1052649..1053155 1 NC_012943.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1053155 ilvH 8162256 ilvH Mycobacterium tuberculosis KZN 1435 acetolactate synthase 3 regulatory subunit YP_003030904.1 1052649 D 478434 CDS YP_003030905.1 253797904 8162257 1053181..1054194 1 NC_012943.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1054194 8162257 TBMG_00969 Mycobacterium tuberculosis KZN 1435 ketol-acid reductoisomerase YP_003030905.1 1053181 D 478434 CDS YP_003030906.1 253797905 8162258 complement(1054508..1055167) 1 NC_012943.1 hypothetical protein 1055167 8162258 TBMG_00970 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030906.1 1054508 R 478434 CDS YP_003030907.1 253797906 8162259 complement(1055212..1056192) 1 NC_012943.1 hypothetical protein 1056192 8162259 TBMG_00971 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030907.1 1055212 R 478434 CDS YP_003030908.1 253797907 8162260 1056351..1056554 1 NC_012943.1 hypothetical protein 1056554 8162260 TBMG_04006 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030908.1 1056351 D 478434 CDS YP_003030909.1 253797908 8162261 complement(1056503..1056964) 1 NC_012943.1 hypothetical protein 1056964 8162261 TBMG_00972 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030909.1 1056503 R 478434 CDS YP_003030910.1 253797909 8162263 1056846..1057046 1 NC_012943.1 hypothetical protein 1057046 8162263 TBMG_04007 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030910.1 1056846 D 478434 CDS YP_003030911.1 253797910 8162262 complement(1057238..1058680) 1 NC_012943.1 hypothetical protein 1058680 8162262 TBMG_00973 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030911.1 1057238 R 478434 CDS YP_003030912.1 253797911 8162264 1058710..1060296 1 NC_012943.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1060296 8162264 TBMG_00974 Mycobacterium tuberculosis KZN 1435 D-3-phosphoglycerate dehydrogenase YP_003030912.1 1058710 D 478434 CDS YP_003030913.1 253797912 8162265 1060311..1061321 1 NC_012943.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1061321 8162265 TBMG_00975 Mycobacterium tuberculosis KZN 1435 3-isopropylmalate dehydrogenase YP_003030913.1 1060311 D 478434 CDS YP_003030914.1 253797913 8162266 complement(1061173..1062510) 1 NC_012943.1 hypothetical protein 1062510 8162266 TBMG_04008 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030914.1 1061173 R 478434 CDS YP_003030915.1 253797914 8162267 1062660..1063505 1 NC_012943.1 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 1063505 8162267 TBMG_00976 Mycobacterium tuberculosis KZN 1435 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase YP_003030915.1 1062660 D 478434 CDS YP_003030916.1 253797915 8162268 1063502..1064974 1 NC_012943.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1064974 gltX 8162268 gltX Mycobacterium tuberculosis KZN 1435 glutamyl-tRNA synthetase YP_003030916.1 1063502 D 478434 CDS YP_003030917.1 253797916 8162271 complement(1065306..1065797) 1 NC_012943.1 hypothetical protein 1065797 8162271 TBMG_00978 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030917.1 1065306 R 478434 CDS YP_003030918.1 253797917 8162272 1066060..1066920 1 NC_012943.1 hypothetical protein 1066920 8162272 TBMG_00979 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030918.1 1066060 D 478434 CDS YP_003030919.1 253797918 8162273 complement(1066931..1067632) 1 NC_012943.1 transcriptional regulator 1067632 8162273 TBMG_00980 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003030919.1 1066931 R 478434 CDS YP_003030920.1 253797919 8162274 1067704..1069125 1 NC_012943.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1069125 8162274 TBMG_00981 Mycobacterium tuberculosis KZN 1435 isopropylmalate isomerase large subunit YP_003030920.1 1067704 D 478434 CDS YP_003030921.1 253797920 8162275 1069150..1069746 1 NC_012943.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1069746 leuD 8162275 leuD Mycobacterium tuberculosis KZN 1435 isopropylmalate isomerase small subunit YP_003030921.1 1069150 D 478434 CDS YP_003030922.1 253797921 8162276 1069959..1070603 1 NC_012943.1 histone-like DNA-binding protein hupB 1070603 8162276 TBMG_00983 Mycobacterium tuberculosis KZN 1435 histone-like DNA-binding protein hupB YP_003030922.1 1069959 D 478434 CDS YP_003030923.1 253797922 8162277 complement(1070661..1071614) 1 NC_012943.1 hydrolase mutT1 1071614 8162277 TBMG_00984 Mycobacterium tuberculosis KZN 1435 hydrolase mutT1 YP_003030923.1 1070661 R 478434 CDS YP_003030924.1 253797923 8162278 complement(1071697..1073925) 1 NC_012943.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 1073925 8162278 TBMG_00985 Mycobacterium tuberculosis KZN 1435 polyphosphate kinase YP_003030924.1 1071697 R 478434 CDS YP_003030925.1 253797924 8162279 complement(1074017..1074688) 1 NC_012943.1 hypothetical protein 1074688 8162279 TBMG_00986 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030925.1 1074017 R 478434 CDS YP_003030926.1 253797925 8162280 1074780..1075784 1 NC_012943.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1075784 gpsA 8162280 gpsA Mycobacterium tuberculosis KZN 1435 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_003030926.1 1074780 D 478434 CDS YP_003030927.1 253797926 8162281 1075907..1076983 1 NC_012943.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1076983 ddl 8162281 ddl Mycobacterium tuberculosis KZN 1435 D-alanyl-alanine synthetase A YP_003030927.1 1075907 D 478434 CDS YP_003030928.1 253797927 8162282 complement(1077099..1077674) 1 NC_012943.1 hypothetical protein 1077674 8162282 TBMG_00989 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030928.1 1077099 R 478434 CDS YP_003030929.1 253797928 8162283 1077856..1078440 1 NC_012943.1 resolvase 1078440 8162283 TBMG_00990 Mycobacterium tuberculosis KZN 1435 resolvase YP_003030929.1 1077856 D 478434 CDS YP_003030930.1 253797929 8162284 1078440..1079819 1 NC_012943.1 transposase 1079819 8162284 TBMG_00991 Mycobacterium tuberculosis KZN 1435 transposase YP_003030930.1 1078440 D 478434 CDS YP_003030931.1 253797930 8162285 1079816..1080817 1 NC_012943.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 1080817 8162285 TBMG_00992 Mycobacterium tuberculosis KZN 1435 thiamine monophosphate kinase YP_003030931.1 1079816 D 478434 CDS YP_003030932.1 253797931 8162286 1080850..1081533 1 NC_012943.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1081533 8162286 TBMG_00993 Mycobacterium tuberculosis KZN 1435 uracil-DNA glycosylase YP_003030932.1 1080850 D 478434 CDS YP_003030933.1 253797932 8162287 complement(1081556..1081750) 1 NC_012943.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1081750 rpmB 8162287 rpmB Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L28 YP_003030933.1 1081556 R 478434 CDS YP_003030934.1 253797933 8162288 1081992..1082246 1 NC_012943.1 hypothetical protein 1082246 8162288 TBMG_00995 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030934.1 1081992 D 478434 CDS YP_003030935.1 253797934 8162289 1082243..1083655 1 NC_012943.1 hypothetical protein 1083655 8162289 TBMG_00996 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030935.1 1082243 D 478434 CDS YP_003030936.1 253797935 8162290 1083658..1085871 1 NC_012943.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1085871 8162290 TBMG_00997 Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA helicase RecG YP_003030936.1 1083658 D 478434 CDS YP_003030937.1 253797936 8162291 1085868..1086581 1 NC_012943.1 hypothetical protein 1086581 8162291 TBMG_00998 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030937.1 1085868 D 478434 CDS YP_003030938.1 253797937 8162292 complement(1086655..1087503) 1 NC_012943.1 oxidoreductase 1087503 8162292 TBMG_00999 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030938.1 1086655 R 478434 CDS YP_003030939.1 253797938 8162293 1087901..1089031 1 NC_012943.1 lipase/esterase 1089031 8162293 TBMG_01000 Mycobacterium tuberculosis KZN 1435 lipase/esterase YP_003030939.1 1087901 D 478434 CDS YP_003030940.1 253797939 8162294 1089110..1089895 1 NC_012943.1 hypothetical protein 1089895 8162294 TBMG_01001 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030940.1 1089110 D 478434 CDS YP_003030941.1 253797940 8162295 1089901..1090533 1 NC_012943.1 hypothetical protein 1090533 8162295 TBMG_01002 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030941.1 1089901 D 478434 CDS YP_003030942.1 253797941 8162296 1090558..1093941 1 NC_012943.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1093941 8162296 TBMG_01003 Mycobacterium tuberculosis KZN 1435 pyruvate carboxylase YP_003030942.1 1090558 D 478434 CDS YP_003030943.1 253797942 8162297 1094137..1094703 1 NC_012943.1 methyltransferase/methylase 1094703 8162297 TBMG_01004 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030943.1 1094137 D 478434 CDS YP_003030944.1 253797943 8162298 1094789..1095274 1 NC_012943.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1095274 coaD 8162298 coaD Mycobacterium tuberculosis KZN 1435 phosphopantetheine adenylyltransferase YP_003030944.1 1094789 D 478434 CDS YP_003030945.1 253797944 8162299 complement(1095318..1095503) 1 NC_012943.1 hypothetical protein 1095503 8162299 TBMG_04009 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030945.1 1095318 R 478434 CDS YP_003030946.1 253797945 8162300 complement(1095619..1096137) 1 NC_012943.1 hypothetical protein 1096137 8162300 TBMG_01006 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030946.1 1095619 R 478434 CDS YP_003030947.1 253797946 8162301 complement(1096143..1097075) 1 NC_012943.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1097075 purU 8162301 purU Mycobacterium tuberculosis KZN 1435 formyltetrahydrofolate deformylase YP_003030947.1 1096143 R 478434 CDS YP_003030948.1 253797947 8162302 complement(1097148..1098368) 1 NC_012943.1 hypothetical protein 1098368 8162302 TBMG_01008 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030948.1 1097148 R 478434 CDS YP_003030949.1 253797948 8162303 1099004..1099831 1 NC_012943.1 truncated CDS; glycosyltransferase 1099831 8162303 TBMG_04010 Mycobacterium tuberculosis KZN 1435 glycosyltransferase YP_003030949.1 1099004 D 478434 CDS YP_003030950.1 253797949 8162304 complement(1099932..1100321) 1 NC_012943.1 transposase 1100321 8162304 TBMG_01010 Mycobacterium tuberculosis KZN 1435 transposase YP_003030950.1 1099932 R 478434 CDS YP_003030951.1 253797950 8162305 1100403..1100651 1 NC_012943.1 hypothetical protein 1100651 8162305 TBMG_01011 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030951.1 1100403 D 478434 CDS YP_003030952.1 253797951 8162306 1100766..1101503 1 NC_012943.1 methyltransferase/methylase 1101503 8162306 TBMG_01012 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030952.1 1100766 D 478434 CDS YP_003030953.1 253797952 8162307 1101604..1102890 1 NC_012943.1 glycosyltransferase 1102890 8162307 TBMG_01013 Mycobacterium tuberculosis KZN 1435 glycosyltransferase YP_003030953.1 1101604 D 478434 CDS YP_003030954.1 253797953 8162308 complement(1103307..1104134) 1 NC_012943.1 glycosyltransferase 1104134 8162308 TBMG_01014 Mycobacterium tuberculosis KZN 1435 glycosyltransferase YP_003030954.1 1103307 R 478434 CDS YP_003030955.1 253797954 8162309 complement(1104205..1104936) 1 NC_012943.1 hypothetical protein 1104936 8162309 TBMG_01015 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030955.1 1104205 R 478434 CDS YP_003030956.1 253797955 8162310 1105050..1106024 1 NC_012943.1 hypothetical protein 1106024 8162310 TBMG_01016 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030956.1 1105050 D 478434 CDS YP_003030957.1 253797956 8162311 1106213..1106938 1 NC_012943.1 hypothetical protein 1106938 8162311 TBMG_01017 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030957.1 1106213 D 478434 CDS YP_003030958.1 253797957 8162312 complement(1107069..1108325) 1 NC_012943.1 hypothetical protein 1108325 8162312 TBMG_01018 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030958.1 1107069 R 478434 CDS YP_003030959.1 253797958 8162313 complement(1108351..1109163) 1 NC_012943.1 methyltransferase/methylase 1109163 8162313 TBMG_01019 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003030959.1 1108351 R 478434 CDS YP_003030960.1 253797959 8162314 1109356..1110501 1 NC_012943.1 oxidoreductase 1110501 8162314 TBMG_01020 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003030960.1 1109356 D 478434 CDS YP_003030961.1 253797960 8162315 1111149..1113008 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1113008 8162315 TBMG_01021 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030961.1 1111149 D 478434 CDS YP_003030962.1 253797961 8162316 1113034..1113633 1 NC_012943.1 hypothetical protein 1113633 8162316 TBMG_01022 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030962.1 1113034 D 478434 CDS YP_003030963.1 253797962 8162317 1113650..1115767 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1115767 8162317 TBMG_01023 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030963.1 1113650 D 478434 CDS YP_003030964.1 253797963 8162318 1115764..1116966 1 NC_012943.1 polyketide synthase 1116966 8162318 TBMG_01024 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003030964.1 1115764 D 478434 CDS YP_003030965.1 253797964 8162319 1116963..1117253 1 NC_012943.1 polyketide synthase 1117253 8162319 TBMG_01025 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003030965.1 1116963 D 478434 CDS YP_003030966.1 253797965 8162320 1117238..1122100 1 NC_012943.1 polyketide synthase 1122100 8162320 TBMG_01026 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003030966.1 1117238 D 478434 CDS YP_003030967.1 253797966 8162321 1122278..1122979 1 NC_012943.1 hypothetical protein 1122979 8162321 TBMG_01027 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030967.1 1122278 D 478434 CDS YP_003030968.1 253797967 8162322 complement(1123097..1123636) 1 NC_012943.1 transposase 1123636 8162322 TBMG_04011 Mycobacterium tuberculosis KZN 1435 transposase YP_003030968.1 1123097 R 478434 CDS YP_003030969.1 253797968 8162323 complement(1123368..1123898) 1 NC_012943.1 transposase 1123898 8162323 TBMG_04012 Mycobacterium tuberculosis KZN 1435 transposase YP_003030969.1 1123368 R 478434 CDS YP_003030970.1 253797969 8162324 complement(1123898..1125139) 1 NC_012943.1 transposase 1125139 8162324 TBMG_01029 Mycobacterium tuberculosis KZN 1435 transposase YP_003030970.1 1123898 R 478434 CDS YP_003030971.1 253797970 8162325 complement(1125771..1128533) 1 NC_012943.1 transmembrane transporter mmpL7 1128533 8162325 TBMG_01030 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL7 YP_003030971.1 1125771 R 478434 CDS YP_003030972.1 253797971 8162326 complement(1128526..1130268) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1130268 8162326 TBMG_01031 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030972.1 1128526 R 478434 CDS YP_003030973.1 253797972 8162327 1130888..1137223 1 NC_012943.1 multifunctional mycocerosic acid synthase membrane-associated mas 1137223 8162327 TBMG_01032 Mycobacterium tuberculosis KZN 1435 multifunctional mycocerosic acid synthase membrane-associated mas YP_003030973.1 1130888 D 478434 CDS YP_003030974.1 253797973 8162328 complement(1137386..1138654) 1 NC_012943.1 required for PDIM synthesis; phthiocerol and phthiodiolone dimycocerosate esters are scaffolds used for virulence-enhancing lipids; proposed to catalyze diesterification of phthiocerol and phthiodolone with mycocerosate; functions in polyketide synthesis; acyltransferase 1138654 8162328 TBMG_01033 Mycobacterium tuberculosis KZN 1435 acyltransferase YP_003030974.1 1137386 R 478434 CDS YP_003030975.1 253797974 8162329 complement(1138701..1139531) 1 NC_012943.1 hypothetical protein 1139531 8162329 TBMG_01034 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030975.1 1138701 R 478434 CDS YP_003030976.1 253797975 8162330 complement(1139528..1140397) 1 NC_012943.1 hypothetical protein 1140397 8162330 TBMG_01035 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030976.1 1139528 R 478434 CDS YP_003030977.1 253797976 8162331 complement(1140394..1141410) 1 NC_012943.1 daunorubicin-dim-transport ATP-binding protein ABC transporter drrA 1141410 8162331 TBMG_01036 Mycobacterium tuberculosis KZN 1435 daunorubicin-dim-transport ATP-binding protein ABC transporter drrA YP_003030977.1 1140394 R 478434 CDS YP_003030978.1 253797977 8162247 complement(1141400..1145866) 1 NC_012943.1 phenolpthiocerol synthesis type-I polyketide synthase ppsE 1145866 8162247 TBMG_01037 Mycobacterium tuberculosis KZN 1435 phenolpthiocerol synthesis type-I polyketide synthase ppsE YP_003030978.1 1141400 R 478434 CDS YP_003030979.1 253797978 8162248 complement(1147139..1151356) 1 NC_012943.1 truncated CDS; phenolpthiocerol synthesis type-I polyketide synthase ppsD 1151356 8162248 TBMG_01038 Mycobacterium tuberculosis KZN 1435 phenolpthiocerol synthesis type-I polyketide synthase ppsD YP_003030979.1 1147139 R 478434 CDS YP_003030980.1 253797979 8162249 complement(1151353..1157919) 1 NC_012943.1 phenolpthiocerol synthesis type-I polyketide synthase ppsC 1157919 8162249 TBMG_01039 Mycobacterium tuberculosis KZN 1435 phenolpthiocerol synthesis type-I polyketide synthase ppsC YP_003030980.1 1151353 R 478434 CDS YP_003030981.1 253797980 8162250 complement(1157916..1162532) 1 NC_012943.1 phenolpthiocerol synthesis type-I polyketide synthase ppsB 1162532 8162250 TBMG_01040 Mycobacterium tuberculosis KZN 1435 phenolpthiocerol synthesis type-I polyketide synthase ppsB YP_003030981.1 1157916 R 478434 CDS YP_003030982.1 253797981 8164322 complement(1164603..1168160) 1 NC_012943.1 truncated CDS; phenolpthiocerol synthesis type-I polyketide synthase ppsA 1168160 8164322 TBMG_01041 Mycobacterium tuberculosis KZN 1435 phenolpthiocerol synthesis type-I polyketide synthase ppsA YP_003030982.1 1164603 R 478434 CDS YP_003030983.1 253797982 8164412 complement(1168157..1170037) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1170037 8164412 TBMG_01042 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003030983.1 1168157 R 478434 CDS YP_003030984.1 253797983 8164413 complement(1170622..1171407) 1 NC_012943.1 thioesterase tesA 1171407 8164413 TBMG_01043 Mycobacterium tuberculosis KZN 1435 thioesterase tesA YP_003030984.1 1170622 R 478434 CDS YP_003030985.1 253797984 8164414 1171646..1172383 1 NC_012943.1 hypothetical protein 1172383 8164414 TBMG_01044 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030985.1 1171646 D 478434 CDS YP_003030986.1 253797985 8164415 1172434..1173057 1 NC_012943.1 hypothetical protein 1173057 8164415 TBMG_01045 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030986.1 1172434 D 478434 CDS YP_003030987.1 253797986 8164416 1173054..1173776 1 NC_012943.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1173776 rnc 8164416 rnc Mycobacterium tuberculosis KZN 1435 ribonuclease III YP_003030987.1 1173054 D 478434 CDS YP_003030988.1 253797987 8164417 1174135..1175004 1 NC_012943.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1175004 8164417 TBMG_01047 Mycobacterium tuberculosis KZN 1435 formamidopyrimidine-DNA glycosylase YP_003030988.1 1174135 D 478434 CDS YP_003030989.1 253797988 8164418 1175106..1175519 1 NC_012943.1 hypothetical protein 1175519 8164418 TBMG_01048 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030989.1 1175106 D 478434 CDS YP_003030990.1 253797989 8164419 1175506..1175787 1 NC_012943.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1175787 8164419 TBMG_01049 Mycobacterium tuberculosis KZN 1435 acylphosphatase YP_003030990.1 1175506 D 478434 CDS YP_003030991.1 253797990 8164420 1175799..1179416 1 NC_012943.1 chromosome partition protein smc 1179416 8164420 TBMG_01050 Mycobacterium tuberculosis KZN 1435 chromosome partition protein smc YP_003030991.1 1175799 D 478434 CDS YP_003030992.1 253797991 8164421 1179466..1180734 1 NC_012943.1 cell division protein ftsY 1180734 8164421 TBMG_01051 Mycobacterium tuberculosis KZN 1435 cell division protein ftsY YP_003030992.1 1179466 D 478434 CDS YP_003030993.1 253797992 8164422 1181323..1182756 1 NC_012943.1 hypothetical protein 1182756 8164422 TBMG_01052 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030993.1 1181323 D 478434 CDS YP_003030994.1 253797993 8164423 1182753..1183091 1 NC_012943.1 nitrogen regulatory protein P-II glnB 1183091 8164423 TBMG_01053 Mycobacterium tuberculosis KZN 1435 nitrogen regulatory protein P-II glnB YP_003030994.1 1182753 D 478434 CDS YP_003030995.1 253797994 8164424 1183149..1184585 1 NC_012943.1 truncated CDS; PII uridylyl-transferase 1184585 8164424 TBMG_01054 Mycobacterium tuberculosis KZN 1435 PII uridylyl-transferase YP_003030995.1 1183149 D 478434 CDS YP_003030996.1 253797995 8164425 complement(1185585..1187465) 1 NC_012943.1 hypothetical protein 1187465 8164425 TBMG_01055 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030996.1 1185585 R 478434 CDS YP_003030997.1 253797996 8164426 1187543..1189120 1 NC_012943.1 signal recognition particle protein ffh 1189120 8164426 TBMG_01056 Mycobacterium tuberculosis KZN 1435 signal recognition particle protein ffh YP_003030997.1 1187543 D 478434 CDS YP_003030998.1 253797997 8164427 1189148..1190260 1 NC_012943.1 hypothetical protein 1190260 8164427 TBMG_01057 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003030998.1 1189148 D 478434 CDS YP_003030999.1 253797998 8164428 1190304..1192061 1 NC_012943.1 Ser/Thr protein kinase 1192061 8164428 TBMG_01058 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003030999.1 1190304 D 478434 CDS YP_003031000.1 253797999 8164429 1192130..1193965 1 NC_012943.1 D-amino acid aminohydrolase 1193965 8164429 TBMG_01059 Mycobacterium tuberculosis KZN 1435 D-amino acid aminohydrolase YP_003031000.1 1192130 D 478434 CDS YP_003031001.1 253798000 8164430 1193967..1194554 1 NC_012943.1 TetR family transcriptional regulator 1194554 8164430 TBMG_01060 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003031001.1 1193967 D 478434 CDS YP_003031002.1 253798001 8164431 complement(1194614..1195489) 1 NC_012943.1 D-alanyl-D-alanine carboxypeptidase dacB2 1195489 8164431 TBMG_01061 Mycobacterium tuberculosis KZN 1435 D-alanyl-D-alanine carboxypeptidase dacB2 YP_003031002.1 1194614 R 478434 CDS YP_003031003.1 253798002 8164432 1195558..1196001 1 NC_012943.1 hypothetical protein 1196001 8164432 TBMG_01062 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031003.1 1195558 D 478434 CDS YP_003031004.1 253798003 8164433 1196185..1196673 1 NC_012943.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1196673 rpsP 8164433 rpsP Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S16 YP_003031004.1 1196185 D 478434 CDS YP_003031005.1 253798004 8164434 1196681..1196923 1 NC_012943.1 hypothetical protein 1196923 8164434 TBMG_01064 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031005.1 1196681 D 478434 CDS YP_003031006.1 253798005 8164435 1196937..1197467 1 NC_012943.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1197467 rimM 8164435 rimM Mycobacterium tuberculosis KZN 1435 16S rRNA-processing protein RimM YP_003031006.1 1196937 D 478434 CDS YP_003031007.1 253798006 8164436 1197471..1198163 1 NC_012943.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1198163 trmD 8164436 trmD Mycobacterium tuberculosis KZN 1435 tRNA (guanine-N(1)-)-methyltransferase YP_003031007.1 1197471 D 478434 CDS YP_003031008.1 253798007 8164437 complement(1198256..1199200) 1 NC_012943.1 hypothetical protein 1199200 8164437 TBMG_01067 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031008.1 1198256 R 478434 CDS YP_003031009.1 253798008 8164438 1199575..1199916 1 NC_012943.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1199916 rplS 8164438 rplS Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L19 YP_003031009.1 1199575 D 478434 CDS YP_003031010.1 253798009 8164439 1199974..1200858 1 NC_012943.1 signal peptidase I lepB 1200858 8164439 TBMG_01069 Mycobacterium tuberculosis KZN 1435 signal peptidase I lepB YP_003031010.1 1199974 D 478434 CDS YP_003031011.1 253798010 8164440 1200872..1201666 1 NC_012943.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1201666 rnhB 8164440 rnhB Mycobacterium tuberculosis KZN 1435 ribonuclease HII YP_003031011.1 1200872 D 478434 CDS YP_003031012.1 253798011 8164441 1201720..1202025 1 NC_012943.1 hypothetical protein 1202025 8164441 TBMG_01071 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031012.1 1201720 D 478434 CDS YP_003031013.1 253798012 8164442 1202083..1204422 1 NC_012943.1 formate dehydrogenase H fdhF 1204422 8164442 TBMG_01072 Mycobacterium tuberculosis KZN 1435 formate dehydrogenase H fdhF YP_003031013.1 1202083 D 478434 CDS YP_003031014.1 253798013 8164443 1204422..1205252 1 NC_012943.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 1205252 8164443 TBMG_01073 Mycobacterium tuberculosis KZN 1435 formate dehydrogenase accessory protein YP_003031014.1 1204422 D 478434 CDS YP_003031015.1 253798014 8164444 1205461..1205886 1 NC_012943.1 hypothetical protein 1205886 8164444 TBMG_01074 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031015.1 1205461 D 478434 CDS YP_003031016.1 253798015 8164445 1205886..1207397 1 NC_012943.1 Mg chelatase 1207397 8164445 TBMG_01075 Mycobacterium tuberculosis KZN 1435 Mg chelatase YP_003031016.1 1205886 D 478434 CDS YP_003031017.1 253798016 8164446 1207394..1208563 1 NC_012943.1 hypothetical protein 1208563 8164446 TBMG_01076 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031017.1 1207394 D 478434 CDS YP_003031018.1 253798017 8164447 1208596..1209447 1 NC_012943.1 mycobactin utilization protein viuB 1209447 8164447 TBMG_01077 Mycobacterium tuberculosis KZN 1435 mycobactin utilization protein viuB YP_003031018.1 1208596 D 478434 CDS YP_003031019.1 253798018 8164448 1209538..1210434 1 NC_012943.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1210434 xerC 8164448 xerC Mycobacterium tuberculosis KZN 1435 site-specific tyrosine recombinase XerC YP_003031019.1 1209538 D 478434 CDS YP_003031020.1 253798019 8164449 complement(1210431..1211408) 1 NC_012943.1 oxidoreductase 1211408 8164449 TBMG_01079 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003031020.1 1210431 R 478434 CDS YP_003031021.1 253798020 8164450 1211820..1213034 1 NC_012943.1 PPE family protein 1213034 8164450 TBMG_01080 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031021.1 1211820 D 478434 CDS YP_003031022.1 253798021 8164451 complement(1212813..1213562) 1 NC_012943.1 hypothetical protein 1213562 8164451 TBMG_04013 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031022.1 1212813 R 478434 CDS YP_003031023.1 253798022 8164452 1213846..1214709 1 NC_012943.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1214709 rpsB 8164452 rpsB Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S2 YP_003031023.1 1213846 D 478434 CDS YP_003031024.1 253798023 8164453 1214721..1215536 1 NC_012943.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1215536 tsf 8164453 tsf Mycobacterium tuberculosis KZN 1435 elongation factor Ts YP_003031024.1 1214721 D 478434 CDS YP_003031025.1 253798024 8164454 1215543..1216964 1 NC_012943.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1216964 8164454 TBMG_01083 Mycobacterium tuberculosis KZN 1435 amidase YP_003031025.1 1215543 D 478434 CDS YP_003031026.1 253798025 8164455 complement(1216978..1217397) 1 NC_012943.1 transcriptional regulator 1217397 8164455 TBMG_01084 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031026.1 1216978 R 478434 CDS YP_003031027.1 253798026 8164457 1217396..1218283 1 NC_012943.1 resolvase 1218283 8164457 TBMG_01085 Mycobacterium tuberculosis KZN 1435 resolvase YP_003031027.1 1217396 D 478434 CDS YP_003031028.1 253798027 8164456 1218280..1219662 1 NC_012943.1 transposase 1219662 8164456 TBMG_01086 Mycobacterium tuberculosis KZN 1435 transposase YP_003031028.1 1218280 D 478434 CDS YP_003031029.1 253798028 8164458 complement(1219677..1220435) 1 NC_012943.1 transcriptional regulator 1220435 8164458 TBMG_01087 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031029.1 1219677 R 478434 CDS YP_003031030.1 253798029 8164459 1220670..1221455 1 NC_012943.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1221455 pyrH 8164459 pyrH Mycobacterium tuberculosis KZN 1435 uridylate kinase YP_003031030.1 1220670 D 478434 CDS YP_003031031.1 253798030 8164460 1221627..1222184 1 NC_012943.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1222184 frr 8164460 frr Mycobacterium tuberculosis KZN 1435 ribosome recycling factor YP_003031031.1 1221627 D 478434 CDS YP_003031032.1 253798031 8164461 1222207..1223127 1 NC_012943.1 membrane phosphatidate cytidylyltransferase cdsA 1223127 8164461 TBMG_01090 Mycobacterium tuberculosis KZN 1435 membrane phosphatidate cytidylyltransferase cdsA YP_003031032.1 1222207 D 478434 CDS YP_003031033.1 253798032 8164462 1223150..1224244 1 NC_012943.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1224244 8164462 TBMG_01091 Mycobacterium tuberculosis KZN 1435 ribosomal RNA large subunit methyltransferase N YP_003031033.1 1223150 D 478434 CDS YP_003031034.1 253798033 8164463 1224430..1224951 1 NC_012943.1 soluble secreted antigen MPT53 precursor 1224951 8164463 TBMG_01092 Mycobacterium tuberculosis KZN 1435 soluble secreted antigen MPT53 precursor YP_003031034.1 1224430 D 478434 CDS YP_003031035.1 253798034 8164464 1224956..1225819 1 NC_012943.1 hypothetical protein 1225819 8164464 TBMG_01093 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031035.1 1224956 D 478434 CDS YP_003031036.1 253798035 8164465 complement(1225850..1226164) 1 NC_012943.1 hypothetical protein 1226164 8164465 TBMG_01094 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031036.1 1225850 R 478434 CDS YP_003031037.1 253798036 8164466 complement(1226216..1226806) 1 NC_012943.1 major secreted immunogenic protein MPT70 1226806 8164466 TBMG_01095 Mycobacterium tuberculosis KZN 1435 major secreted immunogenic protein MPT70 YP_003031037.1 1226216 R 478434 CDS YP_003031038.1 253798037 8164467 complement(1226893..1228980) 1 NC_012943.1 cytochrome C biogenesis protein dipZ 1228980 8164467 TBMG_01096 Mycobacterium tuberculosis KZN 1435 cytochrome C biogenesis protein dipZ YP_003031038.1 1226893 R 478434 CDS YP_003031039.1 253798038 8164468 complement(1229260..1229979) 1 NC_012943.1 cell surface lipoprotein MPT83 1229979 8164468 TBMG_01097 Mycobacterium tuberculosis KZN 1435 cell surface lipoprotein MPT83 YP_003031039.1 1229260 R 478434 CDS YP_003031040.1 253798039 8164469 complement(1230002..1230445) 1 NC_012943.1 toxin 1230445 8164469 TBMG_04014 Mycobacterium tuberculosis KZN 1435 toxin YP_003031040.1 1230002 R 478434 CDS YP_003031041.1 253798040 8164470 complement(1230432..1230689) 1 NC_012943.1 antitoxin 1230689 8164470 TBMG_04015 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031041.1 1230432 R 478434 CDS YP_003031042.1 253798041 8164471 1230768..1232057 1 NC_012943.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1232057 8164471 TBMG_01099 Mycobacterium tuberculosis KZN 1435 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_003031042.1 1230768 D 478434 CDS YP_003031043.1 253798042 8164472 1232065..1233279 1 NC_012943.1 hypothetical protein 1233279 8164472 TBMG_01100 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031043.1 1232065 D 478434 CDS YP_003031044.1 253798043 8164473 1233296..1234459 1 NC_012943.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1234459 ispG 8164473 ispG Mycobacterium tuberculosis KZN 1435 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_003031044.1 1233296 D 478434 CDS YP_003031045.1 253798044 8164474 1234515..1235369 1 NC_012943.1 hypothetical protein 1235369 8164474 TBMG_01102 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031045.1 1234515 D 478434 CDS YP_003031046.1 253798045 8164475 complement(1235742..1236005) 1 NC_012943.1 toxin 1236005 8164475 TBMG_01103 Mycobacterium tuberculosis KZN 1435 toxin YP_003031046.1 1235742 R 478434 CDS YP_003031047.1 253798046 8164476 complement(1236009..1236290) 1 NC_012943.1 antitoxin 1236290 8164476 TBMG_01104 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031047.1 1236009 R 478434 CDS YP_003031048.1 253798047 8164477 1236517..1238373 1 NC_012943.1 penicillin-binding lipoprotein 1238373 8164477 TBMG_01105 Mycobacterium tuberculosis KZN 1435 penicillin-binding lipoprotein YP_003031048.1 1236517 D 478434 CDS YP_003031049.1 253798048 8164478 complement(1238455..1238835) 1 NC_012943.1 toxin 1238835 8164478 TBMG_01106 Mycobacterium tuberculosis KZN 1435 toxin YP_003031049.1 1238455 R 478434 CDS YP_003031050.1 253798049 8164479 complement(1238832..1239080) 1 NC_012943.1 antitoxin 1239080 8164479 TBMG_01107 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031050.1 1238832 R 478434 CDS YP_003031051.1 253798050 8164480 1239184..1239768 1 NC_012943.1 hypothetical protein 1239768 8164480 TBMG_01108 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031051.1 1239184 D 478434 CDS YP_003031052.1 253798051 8164481 1239810..1240667 1 NC_012943.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase 1240667 8164481 TBMG_01109 Mycobacterium tuberculosis KZN 1435 methionine aminopeptidase YP_003031052.1 1239810 D 478434 CDS YP_003031053.1 253798052 8164482 1240827..1242200 1 NC_012943.1 glutamine synthetase glnA4 1242200 8164482 TBMG_01110 Mycobacterium tuberculosis KZN 1435 glutamine synthetase glnA4 YP_003031053.1 1240827 D 478434 CDS YP_003031054.1 253798053 8164483 1242181..1243107 1 NC_012943.1 amidotransferase 1243107 8164483 TBMG_01111 Mycobacterium tuberculosis KZN 1435 amidotransferase YP_003031054.1 1242181 D 478434 CDS YP_003031055.1 253798054 8164484 1243104..1244471 1 NC_012943.1 aldehyde dehydrogenase 1244471 8164484 TBMG_01112 Mycobacterium tuberculosis KZN 1435 aldehyde dehydrogenase YP_003031055.1 1243104 D 478434 CDS YP_003031056.1 253798055 8164485 1244468..1245244 1 NC_012943.1 short chain dehydrogenase 1245244 8164485 TBMG_01113 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003031056.1 1244468 D 478434 CDS YP_003031057.1 253798056 8164486 complement(1245400..1245615) 1 NC_012943.1 hypothetical protein 1245615 8164486 TBMG_01114 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031057.1 1245400 R 478434 CDS YP_003031058.1 253798057 8164487 complement(1245627..1245959) 1 NC_012943.1 hypothetical protein 1245959 8164487 TBMG_01115 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031058.1 1245627 R 478434 CDS YP_003031059.1 253798058 8164488 complement(1246025..1247143) 1 NC_012943.1 hypothetical protein 1247143 8164488 TBMG_01116 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031059.1 1246025 R 478434 CDS YP_003031060.1 253798059 8164489 complement(1247243..1248622) 1 NC_012943.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; mycothione reductase 1248622 8164489 TBMG_01117 Mycobacterium tuberculosis KZN 1435 mycothione reductase YP_003031060.1 1247243 R 478434 CDS YP_003031061.1 253798060 8164490 complement(1248635..1249675) 1 NC_012943.1 hypothetical protein 1249675 8164490 TBMG_01118 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031061.1 1248635 R 478434 CDS YP_003031062.1 253798061 8164491 complement(1249712..1251703) 1 NC_012943.1 PE-PGRS family protein 1251703 8164491 TBMG_01119 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031062.1 1249712 R 478434 CDS YP_003031063.1 253798062 8164492 1251766..1253247 1 NC_012943.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1253247 8164492 TBMG_01120 Mycobacterium tuberculosis KZN 1435 malate:quinone oxidoreductase YP_003031063.1 1251766 D 478434 CDS YP_003031064.1 253798063 8163377 1253306..1253776 1 NC_012943.1 hypothetical protein 1253776 8163377 TBMG_01121 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031064.1 1253306 D 478434 CDS YP_003031065.1 253798064 8162744 1253773..1255662 1 NC_012943.1 magnesium chelatase 1255662 8162744 TBMG_01122 Mycobacterium tuberculosis KZN 1435 magnesium chelatase YP_003031065.1 1253773 D 478434 CDS YP_003031066.1 253798065 8162745 1255683..1256306 1 NC_012943.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1256306 8162745 TBMG_01123 Mycobacterium tuberculosis KZN 1435 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_003031066.1 1255683 D 478434 CDS YP_003031067.1 253798066 8162746 1256306..1257679 1 NC_012943.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1257679 8162746 TBMG_01124 Mycobacterium tuberculosis KZN 1435 cobyrinic acid a,c-diamide synthase YP_003031067.1 1256306 D 478434 CDS YP_003031068.1 253798067 8162747 1257956..1259173 1 NC_012943.1 multifunctional siroheme synthase cysG 1259173 8162747 TBMG_01125 Mycobacterium tuberculosis KZN 1435 multifunctional siroheme synthase cysG YP_003031068.1 1257956 D 478434 CDS YP_003031069.1 253798068 8162748 1259196..1260788 1 NC_012943.1 membrane efflux protein efpA 1260788 8162748 TBMG_01126 Mycobacterium tuberculosis KZN 1435 membrane efflux protein efpA YP_003031069.1 1259196 D 478434 CDS YP_003031070.1 253798069 8162749 1260877..1262625 1 NC_012943.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1262625 8162749 TBMG_01127 Mycobacterium tuberculosis KZN 1435 prolyl-tRNA synthetase YP_003031070.1 1260877 D 478434 CDS YP_003031071.1 253798070 8162750 complement(1262626..1263114) 1 NC_012943.1 hypothetical protein 1263114 8162750 TBMG_01128 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031071.1 1262626 R 478434 CDS YP_003031072.1 253798071 8162751 complement(1263111..1263656) 1 NC_012943.1 hypothetical protein 1263656 8162751 TBMG_01129 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031072.1 1263111 R 478434 CDS YP_003031073.1 253798072 8162752 1263851..1264402 1 NC_012943.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1264402 8162752 TBMG_01130 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031073.1 1263851 D 478434 CDS YP_003031074.1 253798073 8162753 1264399..1265442 1 NC_012943.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1265442 nusA 8162753 nusA Mycobacterium tuberculosis KZN 1435 transcription elongation factor NusA YP_003031074.1 1264399 D 478434 CDS YP_003031075.1 253798074 8162754 1265569..1265868 1 NC_012943.1 hypothetical protein 1265868 8162754 TBMG_01132 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031075.1 1265569 D 478434 CDS YP_003031076.1 253798075 8162755 1265954..1268656 1 NC_012943.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1268656 infB 8162755 infB Mycobacterium tuberculosis KZN 1435 translation initiation factor IF-2 YP_003031076.1 1265954 D 478434 CDS YP_003031077.1 253798076 8162756 1268656..1269207 1 NC_012943.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1269207 rbfA 8162756 rbfA Mycobacterium tuberculosis KZN 1435 ribosome-binding factor A YP_003031077.1 1268656 D 478434 CDS YP_003031078.1 253798077 8162757 1269182..1270192 1 NC_012943.1 hypothetical protein 1270192 8162757 TBMG_01135 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031078.1 1269182 D 478434 CDS YP_003031079.1 253798078 8162758 1270199..1271518 1 NC_012943.1 DNA-damage-inducible protein F dinF 1271518 8162758 TBMG_01136 Mycobacterium tuberculosis KZN 1435 DNA-damage-inducible protein F dinF YP_003031079.1 1270199 D 478434 CDS YP_003031080.1 253798079 8162759 1271605..1272516 1 NC_012943.1 hypothetical protein 1272516 8162759 TBMG_01137 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031080.1 1271605 D 478434 CDS YP_003031081.1 253798080 8162760 1272513..1273340 1 NC_012943.1 hypothetical protein 1273340 8162760 TBMG_01138 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031081.1 1272513 D 478434 CDS YP_003031082.1 253798081 8162761 1273343..1274653 1 NC_012943.1 sn-glycerol-3-phosphate-binding lipoprotein ugpB 1274653 8162761 TBMG_01139 Mycobacterium tuberculosis KZN 1435 sn-glycerol-3-phosphate-binding lipoprotein ugpB YP_003031082.1 1273343 D 478434 CDS YP_003031083.1 253798082 8162762 1274646..1275728 1 NC_012943.1 sn-glycerol-3-phosphate transport ATP-binding protein ABC transporter ugpC 1275728 8162762 TBMG_01140 Mycobacterium tuberculosis KZN 1435 sn-glycerol-3-phosphate transport ATP-binding protein ABC transporter ugpC YP_003031083.1 1274646 D 478434 CDS YP_003031084.1 253798083 8162763 complement(1275807..1276556) 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1276556 8162763 TBMG_01141 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003031084.1 1275807 R 478434 CDS YP_003031085.1 253798084 8162764 1276603..1276818 1 NC_012943.1 antitoxin 1276818 8162764 TBMG_01142 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031085.1 1276603 D 478434 CDS YP_003031086.1 253798085 8162765 1276815..1277207 1 NC_012943.1 toxin 1277207 8162765 TBMG_01143 Mycobacterium tuberculosis KZN 1435 toxin YP_003031086.1 1276815 D 478434 CDS YP_003031087.1 253798086 8162766 1277228..1277497 1 NC_012943.1 hypothetical protein 1277497 8162766 TBMG_01144 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031087.1 1277228 D 478434 CDS YP_003031088.1 253798087 8162767 1277494..1278039 1 NC_012943.1 hypothetical protein 1278039 8162767 TBMG_01145 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031088.1 1277494 D 478434 CDS YP_003031089.1 253798088 8162768 1278329..1279231 1 NC_012943.1 hypothetical protein 1279231 8162768 TBMG_01146 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031089.1 1278329 D 478434 CDS YP_003031090.1 253798089 8162769 1279228..1280118 1 NC_012943.1 hypothetical protein 1280118 8162769 TBMG_01147 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031090.1 1279228 D 478434 CDS YP_003031091.1 253798090 8162770 1280195..1280935 1 NC_012943.1 hypothetical protein 1280935 8162770 TBMG_01148 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031091.1 1280195 D 478434 CDS YP_003031092.1 253798091 8162771 1281113..1282057 1 NC_012943.1 hypothetical protein 1282057 8162771 TBMG_01149 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031092.1 1281113 D 478434 CDS YP_003031093.1 253798092 8162772 1282054..1284492 1 NC_012943.1 hypothetical protein 1284492 8162772 TBMG_01150 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031093.1 1282054 D 478434 CDS YP_003031094.1 253798093 8162773 1284489..1284863 1 NC_012943.1 hypothetical protein 1284863 8162773 TBMG_01151 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031094.1 1284489 D 478434 CDS YP_003031095.1 253798094 8162774 1284873..1285583 1 NC_012943.1 csm3 family CRISPR-associated ramp protein 1285583 8162774 TBMG_01152 Mycobacterium tuberculosis KZN 1435 csm3 family CRISPR-associated ramp protein YP_003031095.1 1284873 D 478434 CDS YP_003031096.1 253798095 8162775 1285564..1286472 1 NC_012943.1 csm4 family CRISPR-associated ramp protein 1286472 8162775 TBMG_01153 Mycobacterium tuberculosis KZN 1435 csm4 family CRISPR-associated ramp protein YP_003031096.1 1285564 D 478434 CDS YP_003031097.1 253798096 8162776 1286469..1287596 1 NC_012943.1 csm5 family CRISPR-associated ramp protein 1287596 8162776 TBMG_01154 Mycobacterium tuberculosis KZN 1435 csm5 family CRISPR-associated ramp protein YP_003031097.1 1286469 D 478434 CDS YP_003031098.1 253798097 8162777 1287593..1288840 1 NC_012943.1 hypothetical protein 1288840 8162777 TBMG_01155 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031098.1 1287593 D 478434 CDS YP_003031099.1 253798098 8162778 1288844..1289869 1 NC_012943.1 hypothetical protein 1289869 8162778 TBMG_01156 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031099.1 1288844 D 478434 CDS YP_003031100.1 253798099 8162779 1289870..1290211 1 NC_012943.1 hypothetical protein 1290211 8162779 TBMG_01157 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031100.1 1289870 D 478434 CDS YP_003031101.1 253798100 8162780 1291904..1292230 1 NC_012943.1 transposase 1292230 8162780 TBMG_01158 Mycobacterium tuberculosis KZN 1435 transposase YP_003031101.1 1291904 D 478434 CDS YP_003031102.1 253798101 8162781 1292281..1293165 1 NC_012943.1 transposase 1293165 8162781 TBMG_01159 Mycobacterium tuberculosis KZN 1435 transposase YP_003031102.1 1292281 D 478434 CDS YP_003031103.1 253798102 8162782 complement(1294621..1295433) 1 NC_012943.1 hypothetical protein 1295433 8162782 TBMG_01160 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031103.1 1294621 R 478434 CDS YP_003031104.1 253798103 8162783 complement(1295430..1296839) 1 NC_012943.1 transposase 1296839 8162783 TBMG_01161 Mycobacterium tuberculosis KZN 1435 transposase YP_003031104.1 1295430 R 478434 CDS YP_003031105.1 253798104 8162784 complement(1296910..1297518) 1 NC_012943.1 hypothetical protein 1297518 8162784 TBMG_01162 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031105.1 1296910 R 478434 CDS YP_003031106.1 253798105 8162785 1297518..1297916 1 NC_012943.1 transposase 1297916 8162785 TBMG_01163 Mycobacterium tuberculosis KZN 1435 transposase YP_003031106.1 1297518 D 478434 CDS YP_003031107.1 253798106 8162786 complement(1297938..1298249) 1 NC_012943.1 hypothetical protein 1298249 8162786 TBMG_01164 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031107.1 1297938 R 478434 CDS YP_003031108.1 253798107 8162787 complement(1298354..1298623) 1 NC_012943.1 hypothetical protein 1298623 8162787 TBMG_01165 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031108.1 1298354 R 478434 CDS YP_003031109.1 253798108 8162788 complement(1298845..1299996) 1 NC_012943.1 hypothetical protein 1299996 8162788 TBMG_01166 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031109.1 1298845 R 478434 CDS YP_003031110.1 253798109 8162789 complement(1300198..1300389) 1 NC_012943.1 hypothetical protein 1300389 8162789 TBMG_01167 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031110.1 1300198 R 478434 CDS YP_003031111.1 253798110 8162790 complement(1300386..1300817) 1 NC_012943.1 hypothetical protein 1300817 8162790 TBMG_01168 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031111.1 1300386 R 478434 CDS YP_003031112.1 253798111 8162791 complement(1300863..1301228) 1 NC_012943.1 histone acetyltransferase 1301228 8162791 TBMG_01169 Mycobacterium tuberculosis KZN 1435 histone acetyltransferase YP_003031112.1 1300863 R 478434 CDS YP_003031113.1 253798112 8162792 complement(1301368..1301835) 1 NC_012943.1 hypothetical protein 1301835 8162792 TBMG_01170 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031113.1 1301368 R 478434 CDS YP_003031114.1 253798113 8162794 1301834..1302877 1 NC_012943.1 hypothetical protein 1302877 8162794 TBMG_01171 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031114.1 1301834 D 478434 CDS YP_003031115.1 253798114 8162793 1302926..1303150 1 NC_012943.1 transcriptional regulator 1303150 8162793 TBMG_01172 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031115.1 1302926 D 478434 CDS YP_003031116.1 253798115 8162795 1303134..1303490 1 NC_012943.1 hypothetical protein 1303490 8162795 TBMG_01173 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031116.1 1303134 D 478434 CDS YP_003031117.1 253798116 8162796 complement(1303592..1305241) 1 NC_012943.1 hydrolase 1305241 8162796 TBMG_01174 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003031117.1 1303592 R 478434 CDS YP_003031118.1 253798117 8162797 complement(1305260..1305889) 1 NC_012943.1 hypothetical protein 1305889 8162797 TBMG_01175 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031118.1 1305260 R 478434 CDS YP_003031119.1 253798118 8162798 1305999..1306346 1 NC_012943.1 hypothetical protein 1306346 8162798 TBMG_01176 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031119.1 1305999 D 478434 CDS YP_003031120.1 253798119 8162799 1306350..1308038 1 NC_012943.1 hypothetical protein 1308038 8162799 TBMG_01177 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031120.1 1306350 D 478434 CDS YP_003031121.1 253798120 8162800 1308038..1308601 1 NC_012943.1 hypothetical protein 1308601 8162800 TBMG_01178 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031121.1 1308038 D 478434 CDS YP_003031122.1 253798121 8162801 1308746..1309720 1 NC_012943.1 hypothetical protein 1309720 8162801 TBMG_01179 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031122.1 1308746 D 478434 CDS YP_003031123.1 253798122 8162802 1309717..1310400 1 NC_012943.1 hypothetical protein 1310400 8162802 TBMG_01180 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031123.1 1309717 D 478434 CDS YP_003031124.1 253798123 8162803 1310397..1311293 1 NC_012943.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1311293 truB 8162803 truB Mycobacterium tuberculosis KZN 1435 tRNA pseudouridine synthase B YP_003031124.1 1310397 D 478434 CDS YP_003031125.1 253798124 8162804 1311495..1312076 1 NC_012943.1 resolvase 1312076 8162804 TBMG_01182 Mycobacterium tuberculosis KZN 1435 resolvase YP_003031125.1 1311495 D 478434 CDS YP_003031126.1 253798125 8162805 1312076..1313455 1 NC_012943.1 transposase 1313455 8162805 TBMG_01183 Mycobacterium tuberculosis KZN 1435 transposase YP_003031126.1 1312076 D 478434 CDS YP_003031127.1 253798126 8162806 1313488..1314693 1 NC_012943.1 lipid-transfer protein 1314693 8162806 TBMG_01184 Mycobacterium tuberculosis KZN 1435 lipid-transfer protein YP_003031127.1 1313488 D 478434 CDS YP_003031128.1 253798127 8162807 1314719..1315951 1 NC_012943.1 acyl-CoA dehydrogenase 1315951 8162807 TBMG_01185 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003031128.1 1314719 D 478434 CDS YP_003031129.1 253798128 8162808 complement(1316012..1316698) 1 NC_012943.1 transcriptional repressor sirR 1316698 8162808 TBMG_01186 Mycobacterium tuberculosis KZN 1435 transcriptional repressor sirR YP_003031129.1 1316012 R 478434 CDS YP_003031130.1 253798129 8162809 complement(1316783..1318546) 1 NC_012943.1 hypothetical protein 1318546 8162809 TBMG_01187 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031130.1 1316783 R 478434 CDS YP_003031131.1 253798130 8162810 1318757..1319752 1 NC_012943.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1319752 8162810 TBMG_01188 Mycobacterium tuberculosis KZN 1435 bifunctional riboflavin kinase/FMN adenylyltransferase YP_003031131.1 1318757 D 478434 CDS YP_003031132.1 253798131 8162811 1319909..1320178 1 NC_012943.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1320178 rpsO 8162811 rpsO Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S15 YP_003031132.1 1319909 D 478434 CDS YP_003031133.1 253798132 8162812 1320191..1320706 1 NC_012943.1 hypothetical protein 1320706 8162812 TBMG_01190 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031133.1 1320191 D 478434 CDS YP_003031134.1 253798133 8162813 1321060..1323318 1 NC_012943.1 polynucleotide phosphorylase 1323318 8162813 TBMG_01191 Mycobacterium tuberculosis KZN 1435 polynucleotide phosphorylase YP_003031134.1 1321060 D 478434 CDS YP_003031135.1 253798134 8162814 1323296..1324612 1 NC_012943.1 zinc protease pepR 1324612 8162814 TBMG_01192 Mycobacterium tuberculosis KZN 1435 zinc protease pepR YP_003031135.1 1323296 D 478434 CDS YP_003031136.1 253798135 8162815 1324673..1325707 1 NC_012943.1 hypothetical protein 1325707 8162815 TBMG_01193 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031136.1 1324673 D 478434 CDS YP_003031137.1 253798136 8162816 complement(1325722..1326837) 1 NC_012943.1 40 kDa secreted L-alanine dehydrogenase ald 1326837 8162816 TBMG_01194 Mycobacterium tuberculosis KZN 1435 40 kDa secreted L-alanine dehydrogenase ald YP_003031137.1 1325722 R 478434 CDS YP_003031138.1 253798137 8162817 1326903..1327442 1 NC_012943.1 transcriptional regulator, lrp/asnC-family 1327442 8162817 TBMG_01195 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, lrp/asnC-family YP_003031138.1 1326903 D 478434 CDS YP_003031139.1 253798138 8162818 1327474..1327944 1 NC_012943.1 hypothetical protein 1327944 8162818 TBMG_01196 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031139.1 1327474 D 478434 CDS YP_003031140.1 253798139 8162819 1328102..1329172 1 NC_012943.1 hypothetical protein 1329172 8162819 TBMG_01197 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031140.1 1328102 D 478434 CDS YP_003031141.1 253798140 8162820 1329192..1330283 1 NC_012943.1 oxidoreductase 1330283 8162820 TBMG_01198 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003031141.1 1329192 D 478434 CDS YP_003031142.1 253798141 8162821 complement(1330496..1331380) 1 NC_012943.1 transposase 1331380 8162821 TBMG_01199 Mycobacterium tuberculosis KZN 1435 transposase YP_003031142.1 1330496 R 478434 CDS YP_003031143.1 253798142 8162822 complement(1331431..1331757) 1 NC_012943.1 transposase 1331757 8162822 TBMG_01200 Mycobacterium tuberculosis KZN 1435 transposase YP_003031143.1 1331431 R 478434 CDS YP_003031144.1 253798143 8162823 1332260..1332664 1 NC_012943.1 hypothetical protein 1332664 8162823 TBMG_01201 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031144.1 1332260 D 478434 CDS YP_003031145.1 253798144 8164404 1332675..1333412 1 NC_012943.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1333412 8164404 TBMG_01202 Mycobacterium tuberculosis KZN 1435 dihydrodipicolinate reductase YP_003031145.1 1332675 D 478434 CDS YP_003031146.1 253798145 8164405 1333424..1333897 1 NC_012943.1 hypothetical protein 1333897 8164405 TBMG_01203 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031146.1 1333424 D 478434 CDS YP_003031147.1 253798146 8164406 1333983..1334435 1 NC_012943.1 hypothetical protein 1334435 8164406 TBMG_01204 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031147.1 1333983 D 478434 CDS YP_003031148.1 253798147 8164604 1334499..1335707 1 NC_012943.1 PPE family protein 1335707 8164604 TBMG_01205 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031148.1 1334499 D 478434 CDS YP_003031149.1 253798148 8164605 1336031..1336858 1 NC_012943.1 PE family protein 1336858 8164605 TBMG_01206 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031149.1 1336031 D 478434 CDS YP_003031150.1 253798149 8164606 1336938..1338122 1 NC_012943.1 PPE family protein 1338122 8164606 TBMG_01207 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031150.1 1336938 D 478434 CDS YP_003031151.1 253798150 8164607 1338123..1338413 1 NC_012943.1 hypothetical protein 1338413 8164607 TBMG_04016 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031151.1 1338123 D 478434 CDS YP_003031152.1 253798151 8164608 1338296..1338649 1 NC_012943.1 hypothetical protein 1338649 8164608 TBMG_04017 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031152.1 1338296 D 478434 CDS YP_003031153.1 253798152 8164609 1338646..1339428 1 NC_012943.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1339428 fabG 8164609 fabG Mycobacterium tuberculosis KZN 1435 3-ketoacyl-ACP reductase YP_003031153.1 1338646 D 478434 CDS YP_003031154.1 253798153 8164610 complement(1339643..1340380) 1 NC_012943.1 hypothetical protein 1340380 8164610 TBMG_01210 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031154.1 1339643 R 478434 CDS YP_003031155.1 253798154 8164611 1340536..1341336 1 NC_012943.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1341336 thyA 8164611 thyA Mycobacterium tuberculosis KZN 1435 thymidylate synthase YP_003031155.1 1340536 D 478434 CDS YP_003031156.1 253798155 8164612 1341401..1341886 1 NC_012943.1 dihydrofolate reductase dfrA 1341886 8164612 TBMG_01212 Mycobacterium tuberculosis KZN 1435 dihydrofolate reductase dfrA YP_003031156.1 1341401 D 478434 CDS YP_003031157.1 253798156 8164613 1341960..1342379 1 NC_012943.1 hypothetical protein 1342379 8164613 TBMG_01213 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031157.1 1341960 D 478434 CDS YP_003031158.1 253798157 8164614 1342376..1343470 1 NC_012943.1 type I restriction/modification system specificity determinant hsdS 1343470 8164614 TBMG_01214 Mycobacterium tuberculosis KZN 1435 type I restriction/modification system specificity determinant hsdS YP_003031158.1 1342376 D 478434 CDS YP_003031159.1 253798158 8164615 1343480..1343749 1 NC_012943.1 antitoxin 1343749 8164615 TBMG_01215 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031159.1 1343480 D 478434 CDS YP_003031160.1 253798159 8164616 1343746..1344141 1 NC_012943.1 toxin 1344141 8164616 TBMG_01216 Mycobacterium tuberculosis KZN 1435 toxin YP_003031160.1 1343746 D 478434 CDS YP_003031161.1 253798160 8164617 1344167..1344433 1 NC_012943.1 antitoxin 1344433 8164617 TBMG_01217 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031161.1 1344167 D 478434 CDS YP_003031162.1 253798161 8164618 1344430..1344846 1 NC_012943.1 toxin 1344846 8164618 TBMG_01218 Mycobacterium tuberculosis KZN 1435 toxin YP_003031162.1 1344430 D 478434 CDS YP_003031163.1 253798162 8164619 1344933..1346555 1 NC_012943.1 type I restriction/modification system DNA methylase hsdM 1346555 8164619 TBMG_01219 Mycobacterium tuberculosis KZN 1435 type I restriction/modification system DNA methylase hsdM YP_003031163.1 1344933 D 478434 CDS YP_003031164.1 253798163 8164620 1346552..1346827 1 NC_012943.1 type I restriction/modification system specificity determinant hsdS_1 1346827 8164620 TBMG_01220 Mycobacterium tuberculosis KZN 1435 type I restriction/modification system specificity determinant hsdS_1 YP_003031164.1 1346552 D 478434 CDS YP_003031165.1 253798164 8164621 1347071..1347823 1 NC_012943.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1347823 thyX 8164621 thyX Mycobacterium tuberculosis KZN 1435 FAD-dependent thymidylate synthase YP_003031165.1 1347071 D 478434 CDS YP_003031166.1 253798165 8164622 1347883..1348794 1 NC_012943.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1348794 8164622 TBMG_01222 Mycobacterium tuberculosis KZN 1435 dihydrodipicolinate synthase YP_003031166.1 1347883 D 478434 CDS YP_003031167.1 253798166 8164623 1348825..1350501 1 NC_012943.1 hypothetical protein 1350501 8164623 TBMG_01223 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031167.1 1348825 D 478434 CDS YP_003031168.1 253798167 8164624 complement(1350488..1351378) 1 NC_012943.1 hypothetical protein 1351378 8164624 TBMG_01224 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031168.1 1350488 R 478434 CDS YP_003031169.1 253798168 8164625 complement(1351382..1352200) 1 NC_012943.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1352200 8164625 TBMG_01225 Mycobacterium tuberculosis KZN 1435 3-ketoacyl-ACP reductase YP_003031169.1 1351382 R 478434 CDS YP_003031170.1 253798169 8164626 complement(1352197..1352511) 1 NC_012943.1 hypothetical protein 1352511 8164626 TBMG_01226 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031170.1 1352197 R 478434 CDS YP_003031171.1 253798170 8164628 1352510..1355161 1 NC_012943.1 hypothetical protein 1355161 8164628 TBMG_01227 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031171.1 1352510 D 478434 CDS YP_003031172.1 253798171 8164627 complement(1355230..1355754) 1 NC_012943.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase 1355754 8164627 TBMG_01228 Mycobacterium tuberculosis KZN 1435 N-acetylglutamate synthase YP_003031172.1 1355230 R 478434 CDS YP_003031173.1 253798172 8164629 1355785..1356414 1 NC_012943.1 phosphatidylglycerophosphate synthase pgsA3 1356414 8164629 TBMG_01229 Mycobacterium tuberculosis KZN 1435 phosphatidylglycerophosphate synthase pgsA3 YP_003031173.1 1355785 D 478434 CDS YP_003031174.1 253798173 8164630 1356485..1356823 1 NC_012943.1 transcriptional regulator 1356823 8164630 TBMG_01230 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031174.1 1356485 D 478434 CDS YP_003031175.1 253798174 8164631 1356953..1357765 1 NC_012943.1 hypothetical protein 1357765 8164631 TBMG_01231 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031175.1 1356953 D 478434 CDS YP_003031176.1 253798175 8164632 1357784..1358596 1 NC_012943.1 hypothetical protein 1358596 8164632 TBMG_01232 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031176.1 1357784 D 478434 CDS YP_003031177.1 253798176 8164633 1358668..1359501 1 NC_012943.1 hypothetical protein 1359501 8164633 TBMG_01233 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031177.1 1358668 D 478434 CDS YP_003031178.1 253798177 8164634 complement(1359525..1361222) 1 NC_012943.1 PE-PGRS family protein 1361222 8164634 TBMG_01234 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031178.1 1359525 R 478434 CDS YP_003031179.1 253798178 8164635 complement(1361161..1361427) 1 NC_012943.1 hypothetical protein 1361427 8164635 TBMG_01235 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031179.1 1361161 R 478434 CDS YP_003031180.1 253798179 8164636 complement(1361334..1361783) 1 NC_012943.1 hypothetical protein 1361783 8164636 TBMG_01236 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031180.1 1361334 R 478434 CDS YP_003031181.1 253798180 8164637 1361827..1362993 1 NC_012943.1 hypothetical protein 1362993 8164637 TBMG_01237 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031181.1 1361827 D 478434 CDS YP_003031182.1 253798181 8164638 complement(1363224..1363397) 1 NC_012943.1 hypothetical protein 1363397 8164638 TBMG_01238 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031182.1 1363224 R 478434 CDS YP_003031183.1 253798182 8164639 1363592..1365964 1 NC_012943.1 these RecA proteins contain inteins; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; DNA recombination protein RecA 1365964 recA 8164639 recA Mycobacterium tuberculosis KZN 1435 DNA recombination protein RecA YP_003031183.1 1363592 D 478434 CDS YP_003031184.1 253798183 8164640 1365930..1366454 1 NC_012943.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1366454 recX 8164640 recX Mycobacterium tuberculosis KZN 1435 recombination regulator RecX YP_003031184.1 1365930 D 478434 CDS YP_003031185.1 253798184 8164641 1366464..1367456 1 NC_012943.1 hypothetical protein 1367456 8164641 TBMG_04018 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031185.1 1366464 D 478434 CDS YP_003031186.1 253798185 8164642 complement(1367341..1368195) 1 NC_012943.1 hypothetical protein 1368195 8164642 TBMG_01241 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031186.1 1367341 R 478434 CDS YP_003031187.1 253798186 8164643 1368393..1370030 1 NC_012943.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1370030 8164643 TBMG_01242 Mycobacterium tuberculosis KZN 1435 (dimethylallyl)adenosine tRNA methylthiotransferase YP_003031187.1 1368393 D 478434 CDS YP_003031188.1 253798187 8164644 1370021..1370641 1 NC_012943.1 hypothetical protein 1370641 8164644 TBMG_01243 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031188.1 1370021 D 478434 CDS YP_003031189.1 253798188 8164645 complement(1370638..1371990) 1 NC_012943.1 hypothetical protein 1371990 8164645 TBMG_01244 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031189.1 1370638 R 478434 CDS YP_003031190.1 253798189 8164646 complement(1371998..1372474) 1 NC_012943.1 hypothetical protein 1372474 8164646 TBMG_01245 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031190.1 1371998 R 478434 CDS YP_003031191.1 253798190 8164647 1372541..1373446 1 NC_012943.1 hypothetical protein 1373446 8164647 TBMG_01246 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031191.1 1372541 D 478434 CDS YP_003031192.1 253798191 8164648 1373555..1374250 1 NC_012943.1 hypothetical protein 1374250 8164648 TBMG_01247 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031192.1 1373555 D 478434 CDS YP_003031193.1 253798192 8164649 1374247..1375191 1 NC_012943.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1375191 miaA 8164649 miaA Mycobacterium tuberculosis KZN 1435 tRNA delta(2)-isopentenylpyrophosphate transferase YP_003031193.1 1374247 D 478434 CDS YP_003031194.1 253798193 8164650 1375216..1376085 1 NC_012943.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1376085 dapF 8164650 dapF Mycobacterium tuberculosis KZN 1435 diaminopimelate epimerase YP_003031194.1 1375216 D 478434 CDS YP_003031195.1 253798194 8164651 1376102..1377589 1 NC_012943.1 GTP-binding protein HflX 1377589 8164651 TBMG_01250 Mycobacterium tuberculosis KZN 1435 GTP-binding protein HflX YP_003031195.1 1376102 D 478434 CDS YP_003031196.1 253798195 8164652 1377725..1378885 1 NC_012943.1 acyl-CoA dehydrogenase 1378885 8164652 TBMG_01251 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003031196.1 1377725 D 478434 CDS YP_003031197.1 253798196 8164653 complement(1378914..1380107) 1 NC_012943.1 hypothetical protein 1380107 8164653 TBMG_01252 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031197.1 1378914 R 478434 CDS YP_003031198.1 253798197 8164654 1380397..1382496 1 NC_012943.1 hypothetical protein 1382496 8164654 TBMG_01253 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031198.1 1380397 D 478434 CDS YP_003031199.1 253798198 8164655 complement(1382518..1383228) 1 NC_012943.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 1383228 8164655 TBMG_01254 Mycobacterium tuberculosis KZN 1435 LexA repressor YP_003031199.1 1382518 R 478434 CDS YP_003031200.1 253798199 8164656 1383479..1383976 1 NC_012943.1 hypothetical protein 1383976 8164656 TBMG_01255 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031200.1 1383479 D 478434 CDS YP_003031201.1 253798200 8164657 1384139..1384603 1 NC_012943.1 transcriptional regulator NrdR 1384603 nrdR 8164657 nrdR Mycobacterium tuberculosis KZN 1435 transcriptional regulator NrdR YP_003031201.1 1384139 D 478434 CDS YP_003031202.1 253798201 8164658 1384655..1385149 1 NC_012943.1 hypothetical protein 1385149 8164658 TBMG_01257 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031202.1 1384655 D 478434 CDS YP_003031203.1 253798202 8164659 complement(1385158..1385844) 1 NC_012943.1 hypothetical protein 1385844 8164659 TBMG_01258 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031203.1 1385158 R 478434 CDS YP_003031204.1 253798203 8164660 complement(1385893..1386918) 1 NC_012943.1 hydrolase 1386918 8164660 TBMG_01259 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003031204.1 1385893 R 478434 CDS YP_003031205.1 253798204 8164661 complement(1386977..1387951) 1 NC_012943.1 hypothetical protein 1387951 8164661 TBMG_01260 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031205.1 1386977 R 478434 CDS YP_003031206.1 253798205 8164662 complement(1388169..1389584) 1 NC_012943.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 1389584 8164662 TBMG_01261 Mycobacterium tuberculosis KZN 1435 soluble pyridine nucleotide transhydrogenase YP_003031206.1 1388169 R 478434 CDS YP_003031207.1 253798206 8164663 1389679..1390746 1 NC_012943.1 hypothetical protein 1390746 8164663 TBMG_01262 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031207.1 1389679 D 478434 CDS YP_003031208.1 253798207 8164664 complement(1390759..1391451) 1 NC_012943.1 iron-dependent repressor and activator ideR 1391451 8164664 TBMG_01263 Mycobacterium tuberculosis KZN 1435 iron-dependent repressor and activator ideR YP_003031208.1 1390759 R 478434 CDS YP_003031209.1 253798208 8164665 complement(1391584..1392621) 1 NC_012943.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase; RNA polymerase sigma factor SigB 1392621 8164665 TBMG_01264 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigB YP_003031209.1 1391584 R 478434 CDS YP_003031210.1 253798209 8164666 complement(1392731..1393177) 1 NC_012943.1 hypothetical protein 1393177 8164666 TBMG_01265 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031210.1 1392731 R 478434 CDS YP_003031211.1 253798210 8164667 1393181..1393468 1 NC_012943.1 hypothetical protein 1393468 8164667 TBMG_01266 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031211.1 1393181 D 478434 CDS YP_003031212.1 253798211 8164668 complement(1393469..1394443) 1 NC_012943.1 hypothetical protein 1394443 8164668 TBMG_01267 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031212.1 1393469 R 478434 CDS YP_003031213.1 253798212 8164669 complement(1394505..1394693) 1 NC_012943.1 hypothetical protein 1394693 8164669 TBMG_04019 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031213.1 1394505 R 478434 CDS YP_003031214.1 253798213 8164670 1394813..1395202 1 NC_012943.1 hypothetical protein 1395202 8164670 TBMG_01268 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031214.1 1394813 D 478434 CDS YP_003031215.1 253798214 8164671 complement(1395130..1395558) 1 NC_012943.1 hypothetical protein 1395558 8164671 TBMG_01269 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031215.1 1395130 R 478434 CDS YP_003031216.1 253798215 8164672 complement(1395595..1397181) 1 NC_012943.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 1397181 8164672 TBMG_01270 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor YP_003031216.1 1395595 R 478434 CDS YP_003031217.1 253798216 8164673 complement(1397361..1398158) 1 NC_012943.1 polyphosphate glucokinase ppgK 1398158 8164673 TBMG_01271 Mycobacterium tuberculosis KZN 1435 polyphosphate glucokinase ppgK YP_003031217.1 1397361 R 478434 CDS YP_003031218.1 253798217 8164674 1398281..1399153 1 NC_012943.1 extragenic suppressor protein suhB 1399153 8164674 TBMG_01272 Mycobacterium tuberculosis KZN 1435 extragenic suppressor protein suhB YP_003031218.1 1398281 D 478434 CDS YP_003031219.1 253798218 8164675 complement(1399163..1399813) 1 NC_012943.1 hypothetical protein 1399813 8164675 TBMG_01273 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031219.1 1399163 R 478434 CDS YP_003031220.1 253798219 8164676 1400051..1400353 1 NC_012943.1 hypothetical protein 1400353 8164676 TBMG_01274 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031220.1 1400051 D 478434 CDS YP_003031221.1 253798220 8164677 complement(1400358..1400843) 1 NC_012943.1 hypothetical protein 1400843 8164677 TBMG_01275 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031221.1 1400358 R 478434 CDS YP_003031222.1 253798221 8164678 1400869..1401333 1 NC_012943.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1401333 dut 8164678 dut Mycobacterium tuberculosis KZN 1435 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_003031222.1 1400869 D 478434 CDS YP_003031223.1 253798222 8164679 1401408..1402187 1 NC_012943.1 hypothetical protein 1402187 8164679 TBMG_01277 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031223.1 1401408 D 478434 CDS YP_003031224.1 253798223 8164680 complement(1402393..1403100) 1 NC_012943.1 hypothetical protein 1403100 8164680 TBMG_01278 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031224.1 1402393 R 478434 CDS YP_003031225.1 253798224 8164681 1403144..1403617 1 NC_012943.1 hypothetical protein 1403617 8164681 TBMG_01279 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031225.1 1403144 D 478434 CDS YP_003031226.1 253798225 8164682 1403648..1404319 1 NC_012943.1 hypothetical protein 1404319 8164682 TBMG_01280 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031226.1 1403648 D 478434 CDS YP_003031227.1 253798226 8164683 complement(1404330..1404992) 1 NC_012943.1 trk system potassium uptake protein ceoC 1404992 8164683 TBMG_01281 Mycobacterium tuberculosis KZN 1435 trk system potassium uptake protein ceoC YP_003031227.1 1404330 R 478434 CDS YP_003031228.1 253798227 8164407 complement(1404989..1405672) 1 NC_012943.1 trk system potassium uptake protein ceoB 1405672 8164407 TBMG_01282 Mycobacterium tuberculosis KZN 1435 trk system potassium uptake protein ceoB YP_003031228.1 1404989 R 478434 CDS YP_003031229.1 253798228 8162334 1405807..1407780 1 NC_012943.1 hypothetical protein 1407780 8162334 TBMG_01283 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031229.1 1405807 D 478434 CDS YP_003031230.1 253798229 8162335 1407954..1409171 1 NC_012943.1 hypothetical protein 1409171 8162335 TBMG_01284 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031230.1 1407954 D 478434 CDS YP_003031231.1 253798230 8162336 1409366..1410271 1 NC_012943.1 antibiotic-transport ATP-binding protein ABC transporter 1410271 8162336 TBMG_01285 Mycobacterium tuberculosis KZN 1435 antibiotic-transport ATP-binding protein ABC transporter YP_003031231.1 1409366 D 478434 CDS YP_003031232.1 253798231 8162337 1410268..1410981 1 NC_012943.1 hypothetical protein 1410981 8162337 TBMG_01286 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031232.1 1410268 D 478434 CDS YP_003031233.1 253798232 8162338 1410978..1411736 1 NC_012943.1 hypothetical protein 1411736 8162338 TBMG_01287 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031233.1 1410978 D 478434 CDS YP_003031234.1 253798233 8162339 complement(1411747..1413033) 1 NC_012943.1 hypothetical protein 1413033 8162339 TBMG_01288 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031234.1 1411747 R 478434 CDS YP_003031235.1 253798234 8162340 complement(1413113..1414402) 1 NC_012943.1 hypothetical protein 1414402 8162340 TBMG_01289 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031235.1 1413113 R 478434 CDS YP_003031236.1 253798235 8162341 complement(1414407..1414904) 1 NC_012943.1 hypothetical protein 1414904 8162341 TBMG_01290 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031236.1 1414407 R 478434 CDS YP_003031237.1 253798236 8162342 1415048..1416964 1 NC_012943.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1416964 8162342 TBMG_01291 Mycobacterium tuberculosis KZN 1435 1-deoxy-D-xylulose-5-phosphate synthase YP_003031237.1 1415048 D 478434 CDS YP_003031238.1 253798237 8162343 complement(1416961..1418277) 1 NC_012943.1 hypothetical protein 1418277 8162343 TBMG_01292 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031238.1 1416961 R 478434 CDS YP_003031239.1 253798238 8162344 complement(1418279..1418911) 1 NC_012943.1 hypothetical protein 1418911 8162344 TBMG_01293 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031239.1 1418279 R 478434 CDS YP_003031240.1 253798239 8162345 complement(1419173..1420003) 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1420003 8162345 TBMG_01294 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003031240.1 1419173 R 478434 CDS YP_003031241.1 253798240 8162346 1420056..1421129 1 NC_012943.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1421129 hemE 8162346 hemE Mycobacterium tuberculosis KZN 1435 uroporphyrinogen decarboxylase YP_003031241.1 1420056 D 478434 CDS YP_003031242.1 253798241 8162347 1421126..1422484 1 NC_012943.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX; protoporphyrinogen oxidase 1422484 8162347 TBMG_01296 Mycobacterium tuberculosis KZN 1435 protoporphyrinogen oxidase YP_003031242.1 1421126 D 478434 CDS YP_003031243.1 253798242 8162348 1422490..1423185 1 NC_012943.1 hypothetical protein 1423185 8162348 TBMG_01297 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031243.1 1422490 D 478434 CDS YP_003031244.1 253798243 8162349 1423182..1423934 1 NC_012943.1 hypothetical protein 1423934 8162349 TBMG_01298 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031244.1 1423182 D 478434 CDS YP_003031245.1 253798244 8162350 complement(1424002..1424412) 1 NC_012943.1 methionine-R-sulfoxide reductase 1424412 8162350 TBMG_01299 Mycobacterium tuberculosis KZN 1435 methionine-R-sulfoxide reductase YP_003031245.1 1424002 R 478434 CDS YP_003031246.1 253798245 8162351 complement(1424581..1425882) 1 NC_012943.1 hypothetical protein 1425882 8162351 TBMG_01300 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031246.1 1424581 R 478434 CDS YP_003031247.1 253798246 8162352 complement(1425905..1427491) 1 NC_012943.1 secreted protease 1427491 8162352 TBMG_01301 Mycobacterium tuberculosis KZN 1435 secreted protease YP_003031247.1 1425905 R 478434 CDS YP_003031248.1 253798247 8162353 complement(1427558..1428334) 1 NC_012943.1 hypothetical protein 1428334 8162353 TBMG_01302 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031248.1 1427558 R 478434 CDS YP_003031249.1 253798248 8162355 1428333..1429442 1 NC_012943.1 hypothetical protein 1429442 8162355 TBMG_01303 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031249.1 1428333 D 478434 CDS YP_003031250.1 253798249 8162354 complement(1429420..1429890) 1 NC_012943.1 hypothetical protein 1429890 8162354 TBMG_01304 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031250.1 1429420 R 478434 CDS YP_003031251.1 253798250 8162356 complement(1429919..1430485) 1 NC_012943.1 hypothetical protein 1430485 8162356 TBMG_01305 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031251.1 1429919 R 478434 CDS YP_003031252.1 253798251 8162357 complement(1430519..1431277) 1 NC_012943.1 ATP-dependent protease ATP-binding subunit clpC2 1431277 8162357 TBMG_01306 Mycobacterium tuberculosis KZN 1435 ATP-dependent protease ATP-binding subunit clpC2 YP_003031252.1 1430519 R 478434 CDS YP_003031253.1 253798252 8162358 complement(1431299..1432165) 1 NC_012943.1 transposase 1432165 8162358 TBMG_01307 Mycobacterium tuberculosis KZN 1435 transposase YP_003031253.1 1431299 R 478434 CDS YP_003031254.1 253798253 8162359 complement(1432193..1432474) 1 NC_012943.1 hypothetical protein 1432474 8162359 TBMG_01308 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031254.1 1432193 R 478434 CDS YP_003031255.1 253798254 8162360 complement(1432822..1433076) 1 NC_012943.1 hypothetical protein 1433076 8162360 TBMG_01309 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031255.1 1432822 R 478434 CDS YP_003031256.1 253798255 8162361 complement(1433087..1433320) 1 NC_012943.1 hypothetical protein 1433320 8162361 TBMG_01310 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031256.1 1433087 R 478434 CDS YP_003031257.1 253798256 8162362 complement(1433419..1433691) 1 NC_012943.1 hypothetical protein 1433691 8162362 TBMG_01311 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031257.1 1433419 R 478434 CDS YP_003031258.1 253798257 8162364 1433597..1433986 1 NC_012943.1 hypothetical protein 1433986 8162364 TBMG_01312 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031258.1 1433597 D 478434 CDS YP_003031259.1 253798258 8162363 1433983..1434210 1 NC_012943.1 hypothetical protein 1434210 8162363 TBMG_01313 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031259.1 1433983 D 478434 CDS YP_003031260.1 253798259 8162365 1434355..1435482 1 NC_012943.1 phiRv2 phage integrase 1435482 8162365 TBMG_01314 Mycobacterium tuberculosis KZN 1435 phiRv2 phage integrase YP_003031260.1 1434355 D 478434 CDS YP_003031261.1 253798260 8162366 1435482..1435847 1 NC_012943.1 phiRv2 phage protein 1435847 8162366 TBMG_01315 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031261.1 1435482 D 478434 CDS YP_003031262.1 253798261 8162367 1435864..1436124 1 NC_012943.1 phiRv2 phage protein 1436124 8162367 TBMG_01316 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031262.1 1435864 D 478434 CDS YP_003031263.1 253798262 8162368 1436121..1436513 1 NC_012943.1 phiRv2 phage protein 1436513 8162368 TBMG_01317 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031263.1 1436121 D 478434 CDS YP_003031264.1 253798263 8162369 1436515..1437942 1 NC_012943.1 phiRv2 phage protein 1437942 8162369 TBMG_01318 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031264.1 1436515 D 478434 CDS YP_003031265.1 253798264 8162370 1437939..1438184 1 NC_012943.1 phiRv2 phage protein 1438184 8162370 TBMG_01319 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031265.1 1437939 D 478434 CDS YP_003031266.1 253798265 8162371 1438171..1438587 1 NC_012943.1 phiRv2 phage protein 1438587 8162371 TBMG_01320 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031266.1 1438171 D 478434 CDS YP_003031267.1 253798266 8162372 1438619..1439245 1 NC_012943.1 phiRv2 phage protein 1439245 8162372 TBMG_01321 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031267.1 1438619 D 478434 CDS YP_003031268.1 253798267 8162373 1439398..1439931 1 NC_012943.1 phiRv2 phage protease 1439931 8162373 TBMG_01322 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protease YP_003031268.1 1439398 D 478434 CDS YP_003031269.1 253798268 8162374 1439939..1441378 1 NC_012943.1 phiRv2 phage protein 1441378 8162374 TBMG_01323 Mycobacterium tuberculosis KZN 1435 phiRv2 phage protein YP_003031269.1 1439939 D 478434 CDS YP_003031270.1 253798269 8162375 complement(1441788..1442252) 1 NC_012943.1 hypothetical protein 1442252 8162375 TBMG_01324 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031270.1 1441788 R 478434 CDS YP_003031271.1 253798270 8162376 complement(1442266..1443264) 1 NC_012943.1 integrase 1443264 8162376 TBMG_01325 Mycobacterium tuberculosis KZN 1435 integrase YP_003031271.1 1442266 R 478434 CDS YP_003031272.1 253798271 8162377 complement(1443261..1443692) 1 NC_012943.1 hypothetical protein 1443692 8162377 TBMG_01326 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031272.1 1443261 R 478434 CDS YP_003031273.1 253798272 8162382 complement(1444983..1445405) 1 NC_012943.1 hypothetical protein 1445405 8162382 TBMG_01327 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031273.1 1444983 R 478434 CDS YP_003031274.1 253798273 8162383 complement(1445409..1446905) 1 NC_012943.1 hypothetical protein 1446905 8162383 TBMG_01328 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031274.1 1445409 R 478434 CDS YP_003031275.1 253798274 8162384 complement(1446902..1447282) 1 NC_012943.1 transcriptional regulator, arsR-family 1447282 8162384 TBMG_01329 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, arsR-family YP_003031275.1 1446902 R 478434 CDS YP_003031276.1 253798275 8162385 complement(1447418..1447876) 1 NC_012943.1 cadmium inducible protein cadI 1447876 8162385 TBMG_01330 Mycobacterium tuberculosis KZN 1435 cadmium inducible protein cadI YP_003031276.1 1447418 R 478434 CDS YP_003031277.1 253798276 8162386 1447978..1448337 1 NC_012943.1 transcriptional regulator, arsR-family 1448337 8162386 TBMG_01331 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, arsR-family YP_003031277.1 1447978 D 478434 CDS YP_003031278.1 253798277 8162387 1448457..1448789 1 NC_012943.1 hypothetical protein 1448789 8162387 TBMG_01332 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031278.1 1448457 D 478434 CDS YP_003031279.1 253798278 8162388 complement(1448964..1449410) 1 NC_012943.1 hypothetical protein 1449410 8162388 TBMG_01333 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031279.1 1448964 R 478434 CDS YP_003031280.1 253798279 8162389 complement(1449573..1450229) 1 NC_012943.1 hypothetical protein 1450229 8162389 TBMG_01334 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031280.1 1449573 R 478434 CDS YP_003031281.1 253798280 8162390 complement(1450425..1451102) 1 NC_012943.1 hypothetical protein 1451102 8162390 TBMG_01335 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031281.1 1450425 R 478434 CDS YP_003031282.1 253798281 8162391 complement(1451103..1451345) 1 NC_012943.1 hypothetical protein 1451345 8162391 TBMG_04020 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031282.1 1451103 R 478434 CDS YP_003031283.1 253798282 8162393 1451344..1453710 1 NC_012943.1 PE-PGRS family protein 1453710 8162393 TBMG_01336 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031283.1 1451344 D 478434 CDS YP_003031284.1 253798283 8162392 1453714..1453968 1 NC_012943.1 hypothetical protein 1453968 8162392 TBMG_01337 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031284.1 1453714 D 478434 CDS YP_003031285.1 253798284 8162394 1453995..1454480 1 NC_012943.1 hypothetical protein 1454480 8162394 TBMG_01338 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031285.1 1453995 D 478434 CDS YP_003031286.1 253798285 8162395 1454625..1454906 1 NC_012943.1 hypothetical protein 1454906 8162395 TBMG_01339 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031286.1 1454625 D 478434 CDS YP_003031287.1 253798286 8162396 complement(1454945..1456243) 1 NC_012943.1 hypothetical protein 1456243 8162396 TBMG_01340 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031287.1 1454945 R 478434 CDS YP_003031288.1 253798287 8162397 complement(1456383..1456922) 1 NC_012943.1 hypothetical protein 1456922 8162397 TBMG_01341 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031288.1 1456383 R 478434 CDS YP_003031289.1 253798288 8162398 complement(1456924..1458048) 1 NC_012943.1 hypothetical protein 1458048 8162398 TBMG_01342 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031289.1 1456924 R 478434 CDS YP_003031290.1 253798289 8162399 complement(1458395..1458757) 1 NC_012943.1 hypothetical protein 1458757 8162399 TBMG_01343 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031290.1 1458395 R 478434 CDS YP_003031291.1 253798290 8162400 1459067..1460308 1 NC_012943.1 hypothetical protein 1460308 8162400 TBMG_01344 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031291.1 1459067 D 478434 CDS YP_003031292.1 253798291 8162401 1460822..1461253 1 NC_012943.1 hypothetical protein 1461253 8162401 TBMG_01345 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031292.1 1460822 D 478434 CDS YP_003031293.1 253798292 8162402 1461312..1462493 1 NC_012943.1 hypothetical protein 1462493 8162402 TBMG_01346 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031293.1 1461312 D 478434 CDS YP_003031294.1 253798293 8162403 1462508..1463326 1 NC_012943.1 hypothetical protein 1463326 8162403 TBMG_01347 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031294.1 1462508 D 478434 CDS YP_003031295.1 253798294 8162404 complement(1463329..1464222) 1 NC_012943.1 hypothetical protein 1464222 8162404 TBMG_01348 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031295.1 1463329 R 478434 CDS YP_003031296.1 253798295 8162405 complement(1464358..1465179) 1 NC_012943.1 methyltransferase/methylase 1465179 8162405 TBMG_01349 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003031296.1 1464358 R 478434 CDS YP_003031297.1 253798296 8162406 1465257..1465931 1 NC_012943.1 transcriptional regulator 1465931 8162406 TBMG_01350 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031297.1 1465257 D 478434 CDS YP_003031298.1 253798297 8162407 1465928..1466353 1 NC_012943.1 hypothetical protein 1466353 8162407 TBMG_01351 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031298.1 1465928 D 478434 CDS YP_003031299.1 253798298 8162408 1466366..1466719 1 NC_012943.1 hypothetical protein 1466719 8162408 TBMG_01352 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031299.1 1466366 D 478434 CDS YP_003031300.1 253798299 8162409 complement(1466704..1467432) 1 NC_012943.1 hypothetical protein 1467432 8162409 TBMG_01353 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031300.1 1466704 R 478434 CDS YP_003031301.1 253798300 8162410 1467528..1467968 1 NC_012943.1 hypothetical protein 1467968 8162410 TBMG_01354 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031301.1 1467528 D 478434 CDS YP_003031302.1 253798301 8162411 complement(1467985..1468485) 1 NC_012943.1 hypothetical protein 1468485 8162411 TBMG_01355 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031302.1 1467985 R 478434 CDS YP_003031303.1 253798302 8164408 1468785..1470215 1 NC_012943.1 PE-PGRS family protein 1470215 8164408 TBMG_01356 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031303.1 1468785 D 478434 CDS YP_003031304.1 253798303 8164409 1470548..1472626 1 NC_012943.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1472626 thrS 8164409 thrS Mycobacterium tuberculosis KZN 1435 threonyl-tRNA synthetase YP_003031304.1 1470548 D 478434 CDS YP_003031305.1 253798304 8163542 1472619..1473206 1 NC_012943.1 hypothetical protein 1473206 8163542 TBMG_01358 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031305.1 1472619 D 478434 CDS YP_003031306.1 253798305 8163543 1473203..1473856 1 NC_012943.1 phosphatidylinositol synthase pgsA1 1473856 8163543 TBMG_01359 Mycobacterium tuberculosis KZN 1435 phosphatidylinositol synthase pgsA1 YP_003031306.1 1473203 D 478434 CDS YP_003031307.1 253798306 8163544 1473853..1474803 1 NC_012943.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1474803 8163544 TBMG_01360 Mycobacterium tuberculosis KZN 1435 lipid A biosynthesis lauroyl acyltransferase YP_003031307.1 1473853 D 478434 CDS YP_003031308.1 253798307 8163545 1474814..1475950 1 NC_012943.1 alpha-mannosyltransferase pimA 1475950 8163545 TBMG_01361 Mycobacterium tuberculosis KZN 1435 alpha-mannosyltransferase pimA YP_003031308.1 1474814 D 478434 CDS YP_003031309.1 253798308 8163546 1475950..1477005 1 NC_012943.1 hypothetical protein 1477005 8163546 TBMG_01362 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031309.1 1475950 D 478434 CDS YP_003031310.1 253798309 8163547 complement(1477027..1478769) 1 NC_012943.1 PPE family protein 1478769 8163547 TBMG_01363 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031310.1 1477027 R 478434 CDS YP_003031311.1 253798310 8163548 complement(1478943..1479617) 1 NC_012943.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1479617 8163548 TBMG_01364 Mycobacterium tuberculosis KZN 1435 pyridoxamine 5'-phosphate oxidase YP_003031311.1 1478943 R 478434 CDS YP_003031312.1 253798311 8163549 1479745..1480644 1 NC_012943.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1480644 8163549 TBMG_01365 Mycobacterium tuberculosis KZN 1435 pyridoxal biosynthesis lyase PdxS YP_003031312.1 1479745 D 478434 CDS YP_003031313.1 253798312 8163550 1480673..1481518 1 NC_012943.1 acyl-CoA thioesterase 1481518 8163550 TBMG_01366 Mycobacterium tuberculosis KZN 1435 acyl-CoA thioesterase YP_003031313.1 1480673 D 478434 CDS YP_003031314.1 253798313 8163551 1481526..1482122 1 NC_012943.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1482122 8163551 TBMG_01367 Mycobacterium tuberculosis KZN 1435 glutamine amidotransferase subunit PdxT YP_003031314.1 1481526 D 478434 CDS YP_003031315.1 253798314 8163552 1482255..1483010 1 NC_012943.1 hypothetical protein 1483010 8163552 TBMG_01368 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031315.1 1482255 D 478434 CDS YP_003031316.1 253798315 8163553 complement(1483031..1483471) 1 NC_012943.1 toxin 1483471 8163553 TBMG_01369 Mycobacterium tuberculosis KZN 1435 toxin YP_003031316.1 1483031 R 478434 CDS YP_003031317.1 253798316 8163554 complement(1483458..1483745) 1 NC_012943.1 antitoxin 1483745 8163554 TBMG_01370 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031317.1 1483458 R 478434 CDS YP_003031318.1 253798317 8163555 complement(1483856..1485427) 1 NC_012943.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 1485427 8163555 TBMG_01371 Mycobacterium tuberculosis KZN 1435 spermidine synthase YP_003031318.1 1483856 R 478434 CDS YP_003031319.1 253798318 8163556 complement(1485424..1485882) 1 NC_012943.1 hypothetical protein 1485882 8163556 TBMG_01372 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031319.1 1485424 R 478434 CDS YP_003031320.1 253798319 8163557 complement(1485907..1486338) 1 NC_012943.1 hypothetical protein 1486338 8163557 TBMG_01373 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031320.1 1485907 R 478434 CDS YP_003031321.1 253798320 8163558 complement(1486335..1486829) 1 NC_012943.1 hypothetical protein 1486829 8163558 TBMG_01374 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031321.1 1486335 R 478434 CDS YP_003031322.1 253798321 8163559 complement(1486840..1487460) 1 NC_012943.1 hypothetical protein 1487460 8163559 TBMG_01375 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031322.1 1486840 R 478434 CDS YP_003031323.1 253798322 8163560 complement(1487677..1488081) 1 NC_012943.1 toxin 1488081 8163560 TBMG_01376 Mycobacterium tuberculosis KZN 1435 toxin YP_003031323.1 1487677 R 478434 CDS YP_003031324.1 253798323 8163561 complement(1488078..1488323) 1 NC_012943.1 antitoxin 1488323 8163561 TBMG_01377 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031324.1 1488078 R 478434 CDS YP_003031325.1 253798324 8163562 1488432..1488998 1 NC_012943.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1488998 ruvC 8163562 ruvC Mycobacterium tuberculosis KZN 1435 Holliday junction resolvase YP_003031325.1 1488432 D 478434 CDS YP_003031326.1 253798325 8163563 1488995..1489585 1 NC_012943.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1489585 ruvA 8163563 ruvA Mycobacterium tuberculosis KZN 1435 Holliday junction DNA helicase RuvA YP_003031326.1 1488995 D 478434 CDS YP_003031327.1 253798326 8163564 1489582..1490616 1 NC_012943.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1490616 ruvB 8163564 ruvB Mycobacterium tuberculosis KZN 1435 Holliday junction DNA helicase RuvB YP_003031327.1 1489582 D 478434 CDS YP_003031328.1 253798327 8163565 complement(1490633..1492294) 1 NC_012943.1 PE-PGRS family protein 1492294 8163565 TBMG_01381 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031328.1 1490633 R 478434 CDS YP_003031329.1 253798328 8163566 complement(1492438..1495944) 1 NC_012943.1 fatty-acid-CoA ligase fadD9 1495944 8163566 TBMG_01382 Mycobacterium tuberculosis KZN 1435 fatty-acid-CoA ligase fadD9 YP_003031329.1 1492438 R 478434 CDS YP_003031330.1 253798329 8163567 complement(1496106..1497455) 1 NC_012943.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 1497455 8163567 TBMG_01383 Mycobacterium tuberculosis KZN 1435 4-aminobutyrate aminotransferase YP_003031330.1 1496106 R 478434 CDS YP_003031331.1 253798330 8163569 1497384..1497593 1 NC_012943.1 hypothetical protein 1497593 8163569 TBMG_01384 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031331.1 1497384 D 478434 CDS YP_003031332.1 253798331 8163568 1497622..1497969 1 NC_012943.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1497969 yajC 8163568 yajC Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit YajC YP_003031332.1 1497622 D 478434 CDS YP_003031333.1 253798332 8163570 1498079..1499800 1 NC_012943.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1499800 secD 8163570 secD Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit SecD YP_003031333.1 1498079 D 478434 CDS YP_003031334.1 253798333 8163571 1499804..1501132 1 NC_012943.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1501132 secF 8163571 secF Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit SecF YP_003031334.1 1499804 D 478434 CDS YP_003031335.1 253798334 8163572 1501138..1502811 1 NC_012943.1 lipoprotein 1502811 8163572 TBMG_01388 Mycobacterium tuberculosis KZN 1435 lipoprotein YP_003031335.1 1501138 D 478434 CDS YP_003031336.1 253798335 8163573 1502915..1503586 1 NC_012943.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1503586 8163573 TBMG_01389 Mycobacterium tuberculosis KZN 1435 adenine phosphoribosyltransferase YP_003031336.1 1502915 D 478434 CDS YP_003031337.1 253798336 8163574 1503608..1505989 1 NC_012943.1 GTP pyrophosphokinase 1505989 8163574 TBMG_01390 Mycobacterium tuberculosis KZN 1435 GTP pyrophosphokinase YP_003031337.1 1503608 D 478434 CDS YP_003031338.1 253798337 8163575 complement(1506075..1507001) 1 NC_012943.1 peptidyl-prolyl-cis-trans-isomerase B ppiB 1507001 8163575 TBMG_01391 Mycobacterium tuberculosis KZN 1435 peptidyl-prolyl-cis-trans-isomerase B ppiB YP_003031338.1 1506075 R 478434 CDS YP_003031339.1 253798338 8163577 1506986..1507726 1 NC_012943.1 glyoxalase II 1507726 8163577 TBMG_01392 Mycobacterium tuberculosis KZN 1435 glyoxalase II YP_003031339.1 1506986 D 478434 CDS YP_003031340.1 253798339 8163576 1507723..1508994 1 NC_012943.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1508994 hisS 8163576 hisS Mycobacterium tuberculosis KZN 1435 histidyl-tRNA synthetase YP_003031340.1 1507723 D 478434 CDS YP_003031341.1 253798340 8163578 complement(1509274..1510176) 1 NC_012943.1 catalyzes the cleavage of carbon-halogen bonds in aliphatic compounds forming a primary alcohol and a halide; haloalkane dehalogenase 1510176 8163578 TBMG_01394 Mycobacterium tuberculosis KZN 1435 haloalkane dehalogenase YP_003031341.1 1509274 R 478434 CDS YP_003031342.1 253798341 8163579 1510284..1511306 1 NC_012943.1 hypothetical protein 1511306 8163579 TBMG_01395 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031342.1 1510284 D 478434 CDS YP_003031343.1 253798342 8163580 complement(1511308..1512897) 1 NC_012943.1 hypothetical protein 1512897 8163580 TBMG_01396 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031343.1 1511308 R 478434 CDS YP_003031344.1 253798343 8163581 1513125..1513589 1 NC_012943.1 hypothetical protein 1513589 8163581 TBMG_01397 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031344.1 1513125 D 478434 CDS YP_003031345.1 253798344 8163582 complement(1513595..1514476) 1 NC_012943.1 hypothetical protein 1514476 8163582 TBMG_01398 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031345.1 1513595 R 478434 CDS YP_003031346.1 253798345 8163583 complement(1514506..1515009) 1 NC_012943.1 hypothetical protein 1515009 8163583 TBMG_01399 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031346.1 1514506 R 478434 CDS YP_003031347.1 253798346 8163584 complement(1515032..1515859) 1 NC_012943.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1515859 8163584 TBMG_01400 Mycobacterium tuberculosis KZN 1435 2-dehydropantoate 2-reductase YP_003031347.1 1515032 R 478434 CDS YP_003031348.1 253798347 8163585 1516012..1517802 1 NC_012943.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1517802 aspS 8163585 aspS Mycobacterium tuberculosis KZN 1435 aspartyl-tRNA synthetase YP_003031348.1 1516012 D 478434 CDS YP_003031349.1 253798348 8163586 1517855..1518922 1 NC_012943.1 hypothetical protein 1518922 8163586 TBMG_01402 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031349.1 1517855 D 478434 CDS YP_003031350.1 253798349 8163587 complement(1518914..1519303) 1 NC_012943.1 hypothetical protein 1519303 8163587 TBMG_01403 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031350.1 1518914 R 478434 CDS YP_003031351.1 253798350 8163588 1519407..1520351 1 NC_012943.1 hypothetical protein 1520351 8163588 TBMG_01404 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031351.1 1519407 D 478434 CDS YP_003031352.1 253798351 8163589 1520344..1521369 1 NC_012943.1 hypothetical protein 1521369 8163589 TBMG_01405 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031352.1 1520344 D 478434 CDS YP_003031353.1 253798352 8163590 complement(1521366..1524020) 1 NC_012943.1 hypothetical protein 1524020 8163590 TBMG_01406 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031353.1 1521366 R 478434 CDS YP_003031354.1 253798353 8163591 complement(1524020..1527442) 1 NC_012943.1 hypothetical protein 1527442 8163591 TBMG_01407 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031354.1 1524020 R 478434 CDS YP_003031355.1 253798354 8163592 complement(1527453..1529204) 1 NC_012943.1 hypothetical protein 1529204 8163592 TBMG_01408 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031355.1 1527453 R 478434 CDS YP_003031356.1 253798355 8163593 complement(1529481..1530473) 1 NC_012943.1 glutamine-transport ATP-binding protein ABC transporter glnQ 1530473 8163593 TBMG_01409 Mycobacterium tuberculosis KZN 1435 glutamine-transport ATP-binding protein ABC transporter glnQ YP_003031356.1 1529481 R 478434 CDS YP_003031357.1 253798356 8163594 complement(1530476..1531525) 1 NC_012943.1 hypothetical protein 1531525 8163594 TBMG_01410 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031357.1 1530476 R 478434 CDS YP_003031358.1 253798357 8163595 complement(1531668..1532405) 1 NC_012943.1 hypothetical protein 1532405 8163595 TBMG_01411 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031358.1 1531668 R 478434 CDS YP_003031359.1 253798358 8163596 1532526..1532849 1 NC_012943.1 hypothetical protein 1532849 8163596 TBMG_04021 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031359.1 1532526 D 478434 CDS YP_003031360.1 253798359 8163597 complement(1532762..1533739) 1 NC_012943.1 hypothetical protein 1533739 8163597 TBMG_01412 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031360.1 1532762 R 478434 CDS YP_003031361.1 253798360 8163598 1533885..1535243 1 NC_012943.1 recombination factor protein RarA 1535243 8163598 TBMG_01413 Mycobacterium tuberculosis KZN 1435 recombination factor protein RarA YP_003031361.1 1533885 D 478434 CDS YP_003031362.1 253798361 8163599 complement(1535273..1535983) 1 NC_012943.1 hypothetical protein 1535983 8163599 TBMG_01414 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031362.1 1535273 R 478434 CDS YP_003031363.1 253798362 8163600 complement(1536068..1536742) 1 NC_012943.1 hypothetical protein 1536742 8163600 TBMG_01415 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031363.1 1536068 R 478434 CDS YP_003031364.1 253798363 8163601 1536837..1537238 1 NC_012943.1 hypothetical protein 1537238 8163601 TBMG_01416 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031364.1 1536837 D 478434 CDS YP_003031365.1 253798364 8163602 1537329..1540043 1 NC_012943.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1540043 alaS 8163602 alaS Mycobacterium tuberculosis KZN 1435 alanyl-tRNA synthetase YP_003031365.1 1537329 D 478434 CDS YP_003031366.1 253798365 8163603 1540044..1540556 1 NC_012943.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1540556 8163603 TBMG_01418 Mycobacterium tuberculosis KZN 1435 Holliday junction resolvase-like protein YP_003031366.1 1540044 D 478434 CDS YP_003031367.1 253798366 8163604 1540549..1541802 1 NC_012943.1 hypothetical protein 1541802 8163604 TBMG_01419 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031367.1 1540549 D 478434 CDS YP_003031368.1 253798367 8163605 1541799..1542608 1 NC_012943.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1542608 aroE 8163605 aroE Mycobacterium tuberculosis KZN 1435 shikimate 5-dehydrogenase YP_003031368.1 1541799 D 478434 CDS YP_003031369.1 253798368 8163606 1542620..1543039 1 NC_012943.1 hypothetical protein 1543039 8163606 TBMG_01421 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031369.1 1542620 D 478434 CDS YP_003031370.1 253798369 8163607 1543450..1543695 1 NC_012943.1 antitoxin 1543695 8163607 TBMG_01422 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031370.1 1543450 D 478434 CDS YP_003031371.1 253798370 8163608 1543692..1544087 1 NC_012943.1 toxin 1544087 8163608 TBMG_01423 Mycobacterium tuberculosis KZN 1435 toxin YP_003031371.1 1543692 D 478434 CDS YP_003031372.1 253798371 8163609 1544187..1544561 1 NC_012943.1 hypothetical protein 1544561 8163609 TBMG_01424 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031372.1 1544187 D 478434 CDS YP_003031373.1 253798372 8163610 complement(1544577..1544954) 1 NC_012943.1 toxin 1544954 8163610 TBMG_01425 Mycobacterium tuberculosis KZN 1435 toxin YP_003031373.1 1544577 R 478434 CDS YP_003031374.1 253798373 8163611 complement(1544951..1545208) 1 NC_012943.1 antitoxin 1545208 8163611 TBMG_01426 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031374.1 1544951 R 478434 CDS YP_003031375.1 253798374 8163612 complement(1545247..1545660) 1 NC_012943.1 toxin 1545660 8163612 TBMG_01427 Mycobacterium tuberculosis KZN 1435 toxin YP_003031375.1 1545247 R 478434 CDS YP_003031376.1 253798375 8163613 complement(1545753..1546031) 1 NC_012943.1 antitoxin 1546031 8163613 TBMG_01428 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031376.1 1545753 R 478434 CDS YP_003031377.1 253798376 8163614 complement(1546028..1546690) 1 NC_012943.1 hypothetical protein 1546690 8163614 TBMG_01429 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031377.1 1546028 R 478434 CDS YP_003031378.1 253798377 8163615 complement(1546687..1547346) 1 NC_012943.1 hypothetical protein 1547346 8163615 TBMG_01430 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031378.1 1546687 R 478434 CDS YP_003031379.1 253798378 8163616 complement(1547473..1548684) 1 NC_012943.1 hypothetical protein 1548684 8163616 TBMG_01431 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031379.1 1547473 R 478434 CDS YP_003031380.1 253798379 8163617 complement(1548980..1549387) 1 NC_012943.1 hypothetical protein 1549387 8163617 TBMG_01432 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031380.1 1548980 R 478434 CDS YP_003031381.1 253798380 8163618 1549402..1550607 1 NC_012943.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1550607 8163618 TBMG_01433 Mycobacterium tuberculosis KZN 1435 chorismate synthase YP_003031381.1 1549402 D 478434 CDS YP_003031382.1 253798381 8163619 1550611..1551141 1 NC_012943.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1551141 aroK 8163619 aroK Mycobacterium tuberculosis KZN 1435 shikimate kinase YP_003031382.1 1550611 D 478434 CDS YP_003031383.1 253798382 8163620 1551138..1552226 1 NC_012943.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1552226 aroB 8163620 aroB Mycobacterium tuberculosis KZN 1435 3-dehydroquinate synthase YP_003031383.1 1551138 D 478434 CDS YP_003031384.1 253798383 8163621 1552223..1552666 1 NC_012943.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1552666 8163621 TBMG_01436 Mycobacterium tuberculosis KZN 1435 3-dehydroquinate dehydratase YP_003031384.1 1552223 D 478434 CDS YP_003031385.1 253798384 8164410 complement(1552670..1553368) 1 NC_012943.1 hypothetical protein 1553368 8164410 TBMG_01437 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031385.1 1552670 R 478434 CDS YP_003031386.1 253798385 8164411 1553396..1554514 1 NC_012943.1 cytoplasmic peptidase pepQ 1554514 8164411 TBMG_01438 Mycobacterium tuberculosis KZN 1435 cytoplasmic peptidase pepQ YP_003031386.1 1553396 D 478434 CDS YP_003031387.1 253798386 8162493 1554524..1555087 1 NC_012943.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1555087 8162493 TBMG_01439 Mycobacterium tuberculosis KZN 1435 elongation factor P YP_003031387.1 1554524 D 478434 CDS YP_003031388.1 253798387 8163209 1555090..1555560 1 NC_012943.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1555560 nusB 8163209 nusB Mycobacterium tuberculosis KZN 1435 transcription antitermination protein NusB YP_003031388.1 1555090 D 478434 CDS YP_003031389.1 253798388 8163210 1555557..1555961 1 NC_012943.1 hypothetical protein 1555961 8163210 TBMG_01441 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031389.1 1555557 D 478434 CDS YP_003031390.1 253798389 8163211 1556033..1558876 1 NC_012943.1 amino acid decarboxylase 1558876 8163211 TBMG_01442 Mycobacterium tuberculosis KZN 1435 amino acid decarboxylase YP_003031390.1 1556033 D 478434 CDS YP_003031391.1 253798390 8163212 1558907..1559131 1 NC_012943.1 antitoxin 1559131 8163212 TBMG_04022 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031391.1 1558907 D 478434 CDS YP_003031392.1 253798391 8163213 1559128..1559547 1 NC_012943.1 toxin 1559547 8163213 TBMG_01443 Mycobacterium tuberculosis KZN 1435 toxin YP_003031392.1 1559128 D 478434 CDS YP_003031393.1 253798392 8163214 complement(1559548..1560558) 1 NC_012943.1 hypothetical protein 1560558 8163214 TBMG_01444 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031393.1 1559548 R 478434 CDS YP_003031394.1 253798393 8163215 1561143..1562063 1 NC_012943.1 restriction system protein mrr 1562063 8163215 TBMG_01445 Mycobacterium tuberculosis KZN 1435 restriction system protein mrr YP_003031394.1 1561143 D 478434 CDS YP_003031395.1 253798394 8163216 complement(1562098..1562499) 1 NC_012943.1 toxin 1562499 8163216 TBMG_01446 Mycobacterium tuberculosis KZN 1435 toxin YP_003031395.1 1562098 R 478434 CDS YP_003031396.1 253798395 8163217 complement(1562496..1562723) 1 NC_012943.1 antitoxin 1562723 8163217 TBMG_04023 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031396.1 1562496 R 478434 CDS YP_003031397.1 253798396 8163218 1563240..1563962 1 NC_012943.1 hypothetical protein 1563962 8163218 TBMG_01447 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031397.1 1563240 D 478434 CDS YP_003031398.1 253798397 8163219 1564482..1573691 1 NC_012943.1 fatty-acid synthase fas 1573691 8163219 TBMG_01448 Mycobacterium tuberculosis KZN 1435 fatty-acid synthase fas YP_003031398.1 1564482 D 478434 CDS YP_003031399.1 253798398 8163220 1573884..1574276 1 NC_012943.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1574276 acpS 8163220 acpS Mycobacterium tuberculosis KZN 1435 4'-phosphopantetheinyl transferase YP_003031399.1 1573884 D 478434 CDS YP_003031400.1 253798399 8163221 1574273..1575685 1 NC_012943.1 hypothetical protein 1575685 8163221 TBMG_01450 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031400.1 1574273 D 478434 CDS YP_003031401.1 253798400 8163222 complement(1575657..1576130) 1 NC_012943.1 bacterioferritin comigratory protein bcp 1576130 8163222 TBMG_01451 Mycobacterium tuberculosis KZN 1435 bacterioferritin comigratory protein bcp YP_003031401.1 1575657 R 478434 CDS YP_003031402.1 253798401 8163223 1576199..1576426 1 NC_012943.1 hypothetical protein 1576426 8163223 TBMG_01452 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031402.1 1576199 D 478434 CDS YP_003031403.1 253798402 8163224 complement(1576551..1578029) 1 NC_012943.1 PE family protein 1578029 8163224 TBMG_01453 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031403.1 1576551 R 478434 CDS YP_003031404.1 253798403 8163226 1578479..1579705 1 NC_012943.1 hypothetical protein 1579705 8163226 TBMG_01454 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031404.1 1578479 D 478434 CDS YP_003031405.1 253798404 8163227 1580301..1581104 1 NC_012943.1 hypothetical protein 1581104 8163227 TBMG_01455 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031405.1 1580301 D 478434 CDS YP_003031406.1 253798405 8163228 1581223..1582470 1 NC_012943.1 hypothetical protein 1582470 8163228 TBMG_01456 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031406.1 1581223 D 478434 CDS YP_003031407.1 253798406 8163229 1582476..1582937 1 NC_012943.1 hypothetical protein 1582937 8163229 TBMG_01457 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031407.1 1582476 D 478434 CDS YP_003031408.1 253798407 8163230 complement(1583231..1583653) 1 NC_012943.1 hypothetical protein 1583653 8163230 TBMG_01458 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031408.1 1583231 R 478434 CDS YP_003031409.1 253798408 8163231 1583948..1585258 1 NC_012943.1 transposase 1585258 8163231 TBMG_01459 Mycobacterium tuberculosis KZN 1435 transposase YP_003031409.1 1583948 D 478434 CDS YP_003031410.1 253798409 8163233 complement(1586010..1586657) 1 NC_012943.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1586657 8163233 TBMG_01460 Mycobacterium tuberculosis KZN 1435 oligoribonuclease YP_003031410.1 1586010 R 478434 CDS YP_003031411.1 253798410 8163234 1586725..1588326 1 NC_012943.1 hypothetical protein 1588326 8163234 TBMG_01461 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031411.1 1586725 D 478434 CDS YP_003031412.1 253798411 8163235 complement(1588330..1589136) 1 NC_012943.1 short-chain type dehydrogenase/reductase 1589136 8163235 TBMG_01462 Mycobacterium tuberculosis KZN 1435 short-chain type dehydrogenase/reductase YP_003031412.1 1588330 R 478434 CDS YP_003031413.1 253798412 8163236 1589212..1590558 1 NC_012943.1 hypothetical protein 1590558 8163236 TBMG_01463 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031413.1 1589212 D 478434 CDS YP_003031414.1 253798413 8163237 complement(1590555..1591376) 1 NC_012943.1 hypothetical protein 1591376 8163237 TBMG_01464 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031414.1 1590555 R 478434 CDS YP_003031415.1 253798414 8163238 complement(1591455..1592102) 1 NC_012943.1 TetR family transcriptional regulator 1592102 8163238 TBMG_01465 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003031415.1 1591455 R 478434 CDS YP_003031416.1 253798415 8163239 1592218..1593861 1 NC_012943.1 AMP-binding protein 1593861 8163239 TBMG_01466 Mycobacterium tuberculosis KZN 1435 AMP-binding protein YP_003031416.1 1592218 D 478434 CDS YP_003031417.1 253798416 8163240 1593944..1594690 1 NC_012943.1 succinyl-CoA:3-ketoacid-coenzyme A transferase alpha subunit scoA 1594690 8163240 TBMG_01467 Mycobacterium tuberculosis KZN 1435 succinyl-CoA:3-ketoacid-coenzyme A transferase alpha subunit scoA YP_003031417.1 1593944 D 478434 CDS YP_003031418.1 253798417 8163241 1594687..1595343 1 NC_012943.1 succinyl-CoA:3-ketoacid-coenzyme A transferase beta subunit scoB 1595343 8163241 TBMG_01468 Mycobacterium tuberculosis KZN 1435 succinyl-CoA:3-ketoacid-coenzyme A transferase beta subunit scoB YP_003031418.1 1594687 D 478434 CDS YP_003031419.1 253798418 8163242 1595340..1596929 1 NC_012943.1 acetyl-/propionyl-CoA carboxylase beta subunit accD1 1596929 8163242 TBMG_01469 Mycobacterium tuberculosis KZN 1435 acetyl-/propionyl-CoA carboxylase beta subunit accD1 YP_003031419.1 1595340 D 478434 CDS YP_003031420.1 253798419 8163243 1596934..1598898 1 NC_012943.1 acetyl-/propionyl-CoA carboxylase alpha subunit accA1 1598898 8163243 TBMG_01470 Mycobacterium tuberculosis KZN 1435 acetyl-/propionyl-CoA carboxylase alpha subunit accA1 YP_003031420.1 1596934 D 478434 CDS YP_003031421.1 253798420 8163244 1598903..1600087 1 NC_012943.1 acyl-CoA dehydrogenase 1600087 8163244 TBMG_01471 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003031421.1 1598903 D 478434 CDS YP_003031422.1 253798421 8163245 1600084..1600641 1 NC_012943.1 oxidase regulatory-related protein 1600641 8163245 TBMG_01472 Mycobacterium tuberculosis KZN 1435 oxidase regulatory-related protein YP_003031422.1 1600084 D 478434 CDS YP_003031423.1 253798422 8163246 1600638..1601459 1 NC_012943.1 citrate (pro-3s)-lyase beta subunit citE 1601459 8163246 TBMG_01473 Mycobacterium tuberculosis KZN 1435 citrate (pro-3s)-lyase beta subunit citE YP_003031423.1 1600638 D 478434 CDS YP_003031424.1 253798423 8163247 1601718..1602821 1 NC_012943.1 pyruvate dehydrogenase E1 component alpha subunit pdhA 1602821 8163247 TBMG_01474 Mycobacterium tuberculosis KZN 1435 pyruvate dehydrogenase E1 component alpha subunit pdhA YP_003031424.1 1601718 D 478434 CDS YP_003031425.1 253798424 8163248 1602832..1603878 1 NC_012943.1 pyruvate dehydrogenase E1 component beta subunit pdhB 1603878 8163248 TBMG_01475 Mycobacterium tuberculosis KZN 1435 pyruvate dehydrogenase E1 component beta subunit pdhB YP_003031425.1 1602832 D 478434 CDS YP_003031426.1 253798425 8163249 1603875..1605056 1 NC_012943.1 branched-chain alpha-keto acid dehydrogenase subunit E2 1605056 8163249 TBMG_01476 Mycobacterium tuberculosis KZN 1435 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_003031426.1 1603875 D 478434 CDS YP_003031427.1 253798426 8163250 complement(1605079..1605504) 1 NC_012943.1 toxin 1605504 8163250 TBMG_01477 Mycobacterium tuberculosis KZN 1435 toxin YP_003031427.1 1605079 R 478434 CDS YP_003031428.1 253798427 8163251 complement(1605510..1605731) 1 NC_012943.1 antitoxin 1605731 8163251 TBMG_01478 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031428.1 1605510 R 478434 CDS YP_003031429.1 253798428 8163252 complement(1605986..1606870) 1 NC_012943.1 transposase 1606870 8163252 TBMG_01479 Mycobacterium tuberculosis KZN 1435 transposase YP_003031429.1 1605986 R 478434 CDS YP_003031430.1 253798429 8163253 complement(1606921..1607247) 1 NC_012943.1 transposase 1607247 8163253 TBMG_01480 Mycobacterium tuberculosis KZN 1435 transposase YP_003031430.1 1606921 R 478434 CDS YP_003031431.1 253798430 8163254 complement(1607884..1608507) 1 NC_012943.1 hypothetical protein 1608507 8163254 TBMG_01481 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031431.1 1607884 R 478434 CDS YP_003031432.1 253798431 8163255 1608643..1608849 1 NC_012943.1 hypothetical protein 1608849 8163255 TBMG_01482 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031432.1 1608643 D 478434 CDS YP_003031433.1 253798432 8163256 1608936..1613786 1 NC_012943.1 hypothetical protein 1613786 8163256 TBMG_04024 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031433.1 1608936 D 478434 CDS YP_003031434.1 253798433 8163257 1613895..1614194 1 NC_012943.1 hypothetical protein 1614194 8163257 TBMG_01485 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031434.1 1613895 D 478434 CDS YP_003031435.1 253798434 8163258 1614160..1617573 1 NC_012943.1 transcriptional regulator, luxR-family 1617573 8163258 TBMG_01486 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, luxR-family YP_003031435.1 1614160 D 478434 CDS YP_003031436.1 253798435 8163259 1617655..1619739 1 NC_012943.1 PE-PGRS family protein 1619739 8163259 TBMG_01487 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031436.1 1617655 D 478434 CDS YP_003031437.1 253798436 8163260 complement(1619920..1620690) 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1620690 8163260 TBMG_01488 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003031437.1 1619920 R 478434 CDS YP_003031438.1 253798437 8163262 1621040..1622317 1 NC_012943.1 carboxylesterase lipQ 1622317 8163262 TBMG_01489 Mycobacterium tuberculosis KZN 1435 carboxylesterase lipQ YP_003031438.1 1621040 D 478434 CDS YP_003031439.1 253798438 8163263 1622540..1624021 1 NC_012943.1 hypothetical protein 1624021 8163263 TBMG_01490 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031439.1 1622540 D 478434 CDS YP_003031440.1 253798439 8163264 1624018..1625760 1 NC_012943.1 bifunctionnal phospholipid biosynthesis enzyme plsC 1625760 8163264 TBMG_01491 Mycobacterium tuberculosis KZN 1435 bifunctionnal phospholipid biosynthesis enzyme plsC YP_003031440.1 1624018 D 478434 CDS YP_003031441.1 253798440 8163265 1625757..1628126 1 NC_012943.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 1628126 8163265 TBMG_01492 Mycobacterium tuberculosis KZN 1435 glycerol-3-phosphate acyltransferase YP_003031441.1 1625757 D 478434 CDS YP_003031442.1 253798441 8163266 1628142..1628465 1 NC_012943.1 hypothetical protein 1628465 8163266 TBMG_01493 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031442.1 1628142 D 478434 CDS YP_003031443.1 253798442 8163267 complement(1628521..1628778) 1 NC_012943.1 hypothetical protein 1628778 8163267 TBMG_01494 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031443.1 1628521 R 478434 CDS YP_003031444.1 253798443 8163268 1629053..1629559 1 NC_012943.1 hypothetical protein 1629559 8163268 TBMG_01495 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031444.1 1629053 D 478434 CDS YP_003031445.1 253798444 8163269 1629640..1631316 1 NC_012943.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1631316 8163269 TBMG_01496 Mycobacterium tuberculosis KZN 1435 ABC transporter ATP-binding protein YP_003031445.1 1629640 D 478434 CDS YP_003031446.1 253798445 8163270 1631420..1636294 1 NC_012943.1 NAD-dependent glutamate dehydrogenase gdh 1636294 8163270 TBMG_01497 Mycobacterium tuberculosis KZN 1435 NAD-dependent glutamate dehydrogenase gdh YP_003031446.1 1631420 D 478434 CDS YP_003031447.1 253798446 8163271 1636291..1636707 1 NC_012943.1 hypothetical protein 1636707 8163271 TBMG_01498 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031447.1 1636291 D 478434 CDS YP_003031448.1 253798447 8163272 1636713..1637363 1 NC_012943.1 hypothetical protein 1637363 8163272 TBMG_01499 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031448.1 1636713 D 478434 CDS YP_003031449.1 253798448 8163273 complement(1637395..1638111) 1 NC_012943.1 hypothetical protein 1638111 8163273 TBMG_01500 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031449.1 1637395 R 478434 CDS YP_003031450.1 253798449 8163274 complement(1638114..1638407) 1 NC_012943.1 hypothetical protein 1638407 8163274 TBMG_01501 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031450.1 1638114 R 478434 CDS YP_003031451.1 253798450 8163275 complement(1638475..1640115) 1 NC_012943.1 alpha-glucosidase 1640115 8163275 TBMG_01502 Mycobacterium tuberculosis KZN 1435 alpha-glucosidase YP_003031451.1 1638475 R 478434 CDS YP_003031452.1 253798451 8163276 complement(1640115..1640519) 1 NC_012943.1 oxygen-binding protein globin glbO 1640519 8163276 TBMG_01503 Mycobacterium tuberculosis KZN 1435 oxygen-binding protein globin glbO YP_003031452.1 1640115 R 478434 CDS YP_003031453.1 253798452 8163277 1640644..1641312 1 NC_012943.1 hypothetical protein 1641312 8163277 TBMG_01504 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031453.1 1640644 D 478434 CDS YP_003031454.1 253798453 8163278 1641532..1642035 1 NC_012943.1 hypothetical protein 1642035 8163278 TBMG_01505 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031454.1 1641532 D 478434 CDS YP_003031455.1 253798454 8163279 complement(1642108..1644693) 1 NC_012943.1 aminopeptidase 1644693 8163279 TBMG_01506 Mycobacterium tuberculosis KZN 1435 aminopeptidase YP_003031455.1 1642108 R 478434 CDS YP_003031456.1 253798455 8163280 1644795..1645418 1 NC_012943.1 hypothetical protein 1645418 8163280 TBMG_01507 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031456.1 1644795 D 478434 CDS YP_003031457.1 253798456 8163281 1645520..1646008 1 NC_012943.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 1646008 8163281 TBMG_01508 Mycobacterium tuberculosis KZN 1435 ribose-5-phosphate isomerase B YP_003031457.1 1645520 D 478434 CDS YP_003031458.1 253798457 8163282 1646014..1646820 1 NC_012943.1 DNA glycosylase 1646820 8163282 TBMG_01509 Mycobacterium tuberculosis KZN 1435 DNA glycosylase YP_003031458.1 1646014 D 478434 CDS YP_003031459.1 253798458 8163283 complement(1646840..1648024) 1 NC_012943.1 esterase/lipase lipP 1648024 8163283 TBMG_01510 Mycobacterium tuberculosis KZN 1435 esterase/lipase lipP YP_003031459.1 1646840 R 478434 CDS YP_003031460.1 253798459 8163286 1648388..1649788 1 NC_012943.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1649788 tig 8163286 tig Mycobacterium tuberculosis KZN 1435 trigger factor YP_003031460.1 1648388 D 478434 CDS YP_003031461.1 253798460 8163287 1649905..1650507 1 NC_012943.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1650507 clpP 8163287 clpP Mycobacterium tuberculosis KZN 1435 ATP-dependent Clp protease proteolytic subunit YP_003031461.1 1649905 D 478434 CDS YP_003031462.1 253798461 8163288 1650504..1651148 1 NC_012943.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1651148 8163288 TBMG_01513 Mycobacterium tuberculosis KZN 1435 ATP-dependent Clp protease proteolytic subunit YP_003031462.1 1650504 D 478434 CDS YP_003031463.1 253798462 8163289 complement(1651299..1652915) 1 NC_012943.1 membrane transporter 1652915 8163289 TBMG_01514 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003031463.1 1651299 R 478434 CDS YP_003031464.1 253798463 8163379 complement(1652992..1653900) 1 NC_012943.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 1653900 mmuM 8163379 mmuM Mycobacterium tuberculosis KZN 1435 homocysteine methyltransferase YP_003031464.1 1652992 R 478434 CDS YP_003031465.1 253798464 8163380 1654191..1655471 1 NC_012943.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1655471 clpX 8163380 clpX Mycobacterium tuberculosis KZN 1435 ATP-dependent protease ATP-binding subunit ClpX YP_003031465.1 1654191 D 478434 CDS YP_003031466.1 253798465 8163381 1655487..1656743 1 NC_012943.1 membrane transporter 1656743 8163381 TBMG_01517 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003031466.1 1655487 D 478434 CDS YP_003031467.1 253798466 8163382 1656960..1658936 1 NC_012943.1 oxidoreductase alpha subunit 1658936 8163382 TBMG_01518 Mycobacterium tuberculosis KZN 1435 oxidoreductase alpha subunit YP_003031467.1 1656960 D 478434 CDS YP_003031468.1 253798467 8163383 1658933..1660054 1 NC_012943.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1660054 8163383 TBMG_01519 Mycobacterium tuberculosis KZN 1435 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_003031468.1 1658933 D 478434 CDS YP_003031469.1 253798468 8163384 1660056..1660661 1 NC_012943.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 1660661 8163384 TBMG_01520 Mycobacterium tuberculosis KZN 1435 molybdopterin-guanine dinucleotide biosynthesis protein A YP_003031469.1 1660056 D 478434 CDS YP_003031470.1 253798469 8163385 complement(1661019..1661417) 1 NC_012943.1 hypothetical protein 1661417 8163385 TBMG_01521 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031470.1 1661019 R 478434 CDS YP_003031471.1 253798470 8163386 1661451..1662017 1 NC_012943.1 resuscitation-promoting factor rpfE 1662017 8163386 TBMG_01522 Mycobacterium tuberculosis KZN 1435 resuscitation-promoting factor rpfE YP_003031471.1 1661451 D 478434 CDS YP_003031472.1 253798471 8163387 1662107..1663366 1 NC_012943.1 saccharopine dehydrogenase 1663366 8163387 TBMG_01523 Mycobacterium tuberculosis KZN 1435 saccharopine dehydrogenase YP_003031472.1 1662107 D 478434 CDS YP_003031473.1 253798472 8163388 1663424..1666084 1 NC_012943.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1666084 valS 8163388 valS Mycobacterium tuberculosis KZN 1435 valyl-tRNA synthetase YP_003031473.1 1663424 D 478434 CDS YP_003031474.1 253798473 8163389 1666081..1667544 1 NC_012943.1 folylpolyglutamate synthase folC 1667544 8163389 TBMG_01525 Mycobacterium tuberculosis KZN 1435 folylpolyglutamate synthase folC YP_003031474.1 1666081 D 478434 CDS YP_003031475.1 253798474 8163390 1667541..1667912 1 NC_012943.1 hypothetical protein 1667912 8163390 TBMG_01526 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031475.1 1667541 D 478434 CDS YP_003031476.1 253798475 8163391 1667955..1668365 1 NC_012943.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1668365 ndk 8163391 ndk Mycobacterium tuberculosis KZN 1435 nucleoside diphosphate kinase YP_003031476.1 1667955 D 478434 CDS YP_003031477.1 253798476 8163392 1668695..1671556 1 NC_012943.1 ribonuclease E rne 1671556 8163392 TBMG_01528 Mycobacterium tuberculosis KZN 1435 ribonuclease E rne YP_003031477.1 1668695 D 478434 CDS YP_003031478.1 253798477 8163393 complement(1671495..1672970) 1 NC_012943.1 hypothetical protein 1672970 8163393 TBMG_01529 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031478.1 1671495 R 478434 CDS YP_003031479.1 253798478 8163394 1673318..1673632 1 NC_012943.1 50S ribosomal protein L21 1673632 rplU 8163394 rplU Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L21 YP_003031479.1 1673318 D 478434 CDS YP_003031480.1 253798479 8163395 1673647..1673907 1 NC_012943.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1673907 rpmA 8163395 rpmA Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L27 YP_003031480.1 1673647 D 478434 CDS YP_003031481.1 253798480 8163396 1673993..1675432 1 NC_012943.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1675432 obgE 8163396 obgE Mycobacterium tuberculosis KZN 1435 GTPase ObgE YP_003031481.1 1673993 D 478434 CDS YP_003031482.1 253798481 8163397 1675432..1676562 1 NC_012943.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1676562 8163397 TBMG_01533 Mycobacterium tuberculosis KZN 1435 gamma-glutamyl kinase YP_003031482.1 1675432 D 478434 CDS YP_003031483.1 253798482 8163398 1676671..1678887 1 NC_012943.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1678887 nadE 8163398 nadE Mycobacterium tuberculosis KZN 1435 NAD synthetase YP_003031483.1 1676671 D 478434 CDS YP_003031484.1 253798483 8163399 complement(1678884..1679303) 1 NC_012943.1 hypothetical protein 1679303 8163399 TBMG_01535 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031484.1 1678884 R 478434 CDS YP_003031485.1 253798484 8163400 complement(1679535..1680449) 1 NC_012943.1 ribokinase rbsK 1680449 8163400 TBMG_01536 Mycobacterium tuberculosis KZN 1435 ribokinase rbsK YP_003031485.1 1679535 R 478434 CDS YP_003031486.1 253798485 8163401 1680930..1683122 1 NC_012943.1 cyclase 1683122 8163401 TBMG_01537 Mycobacterium tuberculosis KZN 1435 cyclase YP_003031486.1 1680930 D 478434 CDS YP_003031487.1 253798486 8163402 1683119..1684564 1 NC_012943.1 hypothetical protein 1684564 8163402 TBMG_01538 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031487.1 1683119 D 478434 CDS YP_003031488.1 253798487 8163403 1684545..1684835 1 NC_012943.1 hypothetical protein 1684835 8163403 TBMG_01539 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031488.1 1684545 D 478434 CDS YP_003031489.1 253798488 8163404 1684832..1685242 1 NC_012943.1 hypothetical protein 1685242 8163404 TBMG_01540 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031489.1 1684832 D 478434 CDS YP_003031490.1 253798489 8163405 1685413..1685712 1 NC_012943.1 PE family protein 1685712 8163405 TBMG_01541 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031490.1 1685413 D 478434 CDS YP_003031491.1 253798490 8163406 1685759..1686343 1 NC_012943.1 PPE family protein 1686343 8163406 TBMG_01542 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031491.1 1685759 D 478434 CDS YP_003031492.1 253798491 8163407 complement(1686340..1686873) 1 NC_012943.1 alkyl hydroperoxide reductase 1686873 8163407 TBMG_01543 Mycobacterium tuberculosis KZN 1435 alkyl hydroperoxide reductase YP_003031492.1 1686340 R 478434 CDS YP_003031493.1 253798492 8163408 complement(1686899..1687486) 1 NC_012943.1 alkyl hydroperoxide reductase 1687486 8163408 TBMG_01544 Mycobacterium tuberculosis KZN 1435 alkyl hydroperoxide reductase YP_003031493.1 1686899 R 478434 CDS YP_003031494.1 253798493 8163409 1687619..1687813 1 NC_012943.1 OxyR protein 1687813 8163409 TBMG_01545 Mycobacterium tuberculosis KZN 1435 OxyR protein YP_003031494.1 1687619 D 478434 CDS YP_003031495.1 253798494 8163410 1687818..1688084 1 NC_012943.1 hydrogen peroxide-inducible genes activator 1688084 8163410 TBMG_01546 Mycobacterium tuberculosis KZN 1435 hydrogen peroxide-inducible genes activator YP_003031495.1 1687818 D 478434 CDS YP_003031496.1 253798495 8163411 1688202..1689449 1 NC_012943.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1689449 proA 8163411 proA Mycobacterium tuberculosis KZN 1435 gamma-glutamyl phosphate reductase YP_003031496.1 1688202 D 478434 CDS YP_003031497.1 253798496 8163412 1689496..1690371 1 NC_012943.1 hypothetical protein 1690371 8163412 TBMG_01548 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031497.1 1689496 D 478434 CDS YP_003031498.1 253798497 8163413 1690371..1691813 1 NC_012943.1 hypothetical protein 1691813 8163413 TBMG_01549 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031498.1 1690371 D 478434 CDS YP_003031499.1 253798498 8163414 1691902..1692903 1 NC_012943.1 transposase 1692903 8163414 TBMG_01550 Mycobacterium tuberculosis KZN 1435 transposase YP_003031499.1 1691902 D 478434 CDS YP_003031500.1 253798499 8163415 complement(1693036..1694082) 1 NC_012943.1 hypothetical protein 1694082 8163415 TBMG_01551 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031500.1 1693036 R 478434 CDS YP_003031501.1 253798500 8163416 complement(1694324..1694596) 1 NC_012943.1 hypothetical protein 1694596 8163416 TBMG_01552 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031501.1 1694324 R 478434 CDS YP_003031502.1 253798501 8163417 1694871..1695506 1 NC_012943.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1695506 nadD 8163417 nadD Mycobacterium tuberculosis KZN 1435 nicotinic acid mononucleotide adenylyltransferase YP_003031502.1 1694871 D 478434 CDS YP_003031503.1 253798502 8163418 1695503..1695883 1 NC_012943.1 hypothetical protein 1695883 8163418 TBMG_01554 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031503.1 1695503 D 478434 CDS YP_003031504.1 253798503 8163419 1695880..1696551 1 NC_012943.1 phosphoglycerate mutase 1696551 8163419 TBMG_01555 Mycobacterium tuberculosis KZN 1435 phosphoglycerate mutase YP_003031504.1 1695880 D 478434 CDS YP_003031505.1 253798504 8163420 1696541..1697284 1 NC_012943.1 hypothetical protein 1697284 8163420 TBMG_01556 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031505.1 1696541 D 478434 CDS YP_003031506.1 253798505 8163421 1697374..1698207 1 NC_012943.1 hypothetical protein 1698207 8163421 TBMG_01557 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031506.1 1697374 D 478434 CDS YP_003031507.1 253798506 8163422 1698329..1699555 1 NC_012943.1 hypothetical protein 1699555 8163422 TBMG_01558 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031507.1 1698329 D 478434 CDS YP_003031508.1 253798507 8163423 1699895..1700791 1 NC_012943.1 hypothetical protein 1700791 8163423 TBMG_01559 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031508.1 1699895 D 478434 CDS YP_003031509.1 253798508 8163424 1700797..1702350 1 NC_012943.1 hypothetical protein 1702350 8163424 TBMG_01560 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031509.1 1700797 D 478434 CDS YP_003031510.1 253798509 8163425 1702363..1703331 1 NC_012943.1 hypothetical protein 1703331 8163425 TBMG_01561 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031510.1 1702363 D 478434 CDS YP_003031511.1 253798510 8163426 complement(1703347..1703607) 1 NC_012943.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1703607 rpsT 8163426 rpsT Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S20 YP_003031511.1 1703347 R 478434 CDS YP_003031512.1 253798511 8163427 1703717..1705372 1 NC_012943.1 hypothetical protein 1705372 8163427 TBMG_01563 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031512.1 1703717 D 478434 CDS YP_003031513.1 253798512 8163428 1705372..1706349 1 NC_012943.1 hypothetical protein 1706349 8163428 TBMG_01564 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031513.1 1705372 D 478434 CDS YP_003031514.1 253798513 8163429 1706349..1707188 1 NC_012943.1 hypothetical protein 1707188 8163429 TBMG_01565 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031514.1 1706349 D 478434 CDS YP_003031515.1 253798514 8163430 complement(1706946..1707950) 1 NC_012943.1 PE family protein 1707950 8163430 TBMG_01566 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031515.1 1706946 R 478434 CDS YP_003031516.1 253798515 8163431 complement(1708164..1709006) 1 NC_012943.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1709006 8163431 TBMG_01567 Mycobacterium tuberculosis KZN 1435 ribonuclease Z YP_003031516.1 1708164 R 478434 CDS YP_003031517.1 253798516 8163432 1709266..1709694 1 NC_012943.1 hypothetical protein 1709694 8163432 TBMG_01568 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031517.1 1709266 D 478434 CDS YP_003031518.1 253798517 8163433 complement(1709865..1710467) 1 NC_012943.1 hypothetical protein 1710467 8163433 TBMG_01569 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031518.1 1709865 R 478434 CDS YP_003031519.1 253798518 8163435 1710455..1712416 1 NC_012943.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1712416 8163435 TBMG_01570 Mycobacterium tuberculosis KZN 1435 GTP-binding protein LepA YP_003031519.1 1710455 D 478434 CDS YP_003031520.1 253798519 8163434 1712413..1713168 1 NC_012943.1 hypothetical protein 1713168 8163434 TBMG_01571 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031520.1 1712413 D 478434 CDS YP_003031521.1 253798520 8163436 complement(1713246..1715174) 1 NC_012943.1 hypothetical protein 1715174 8163436 TBMG_01572 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031521.1 1713246 R 478434 CDS YP_003031522.1 253798521 8163437 1715458..1715661 1 NC_012943.1 hypothetical protein 1715661 8163437 TBMG_01573 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031522.1 1715458 D 478434 CDS YP_003031523.1 253798522 8163438 complement(1715646..1715975) 1 NC_012943.1 hypothetical protein 1715975 8163438 TBMG_01574 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031523.1 1715646 R 478434 CDS YP_003031524.1 253798523 8163439 1715989..1717059 1 NC_012943.1 sulfate-binding lipoprotein subI 1717059 8163439 TBMG_01575 Mycobacterium tuberculosis KZN 1435 sulfate-binding lipoprotein subI YP_003031524.1 1715989 D 478434 CDS YP_003031525.1 253798524 8163440 1717056..1717907 1 NC_012943.1 hypothetical protein 1717907 8163440 TBMG_01576 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031525.1 1717056 D 478434 CDS YP_003031526.1 253798525 8163441 1717904..1718722 1 NC_012943.1 hypothetical protein 1718722 8163441 TBMG_01577 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031526.1 1717904 D 478434 CDS YP_003031527.1 253798526 8163442 1718739..1719794 1 NC_012943.1 sulfate-transport ATP-binding protein ABC transporter cysA1 1719794 8163442 TBMG_01578 Mycobacterium tuberculosis KZN 1435 sulfate-transport ATP-binding protein ABC transporter cysA1 YP_003031527.1 1718739 D 478434 CDS YP_003031528.1 253798527 8163443 complement(1719819..1720967) 1 NC_012943.1 PE-PGRS family protein 1720967 8163443 TBMG_01579 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031528.1 1719819 R 478434 CDS YP_003031529.1 253798528 8163444 complement(1721628..1723631) 1 NC_012943.1 hypothetical protein 1723631 8163444 TBMG_01580 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031529.1 1721628 R 478434 CDS YP_003031530.1 253798529 8163445 complement(1723762..1725693) 1 NC_012943.1 gamma-glutamyltranspeptidase precursor ggtB 1725693 8163445 TBMG_01581 Mycobacterium tuberculosis KZN 1435 gamma-glutamyltranspeptidase precursor ggtB YP_003031530.1 1723762 R 478434 CDS YP_003031531.1 253798530 8163446 complement(1725730..1726575) 1 NC_012943.1 hypothetical protein 1726575 8163446 TBMG_01582 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031531.1 1725730 R 478434 CDS YP_003031532.1 253798531 8163447 complement(1726572..1727336) 1 NC_012943.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 1727336 8163447 TBMG_01583 Mycobacterium tuberculosis KZN 1435 phosphoadenosine phosphosulfate reductase YP_003031532.1 1726572 R 478434 CDS YP_003031533.1 253798532 8163448 complement(1727333..1729024) 1 NC_012943.1 ferredoxin-dependent nitrite reductase nirA 1729024 8163448 TBMG_01584 Mycobacterium tuberculosis KZN 1435 ferredoxin-dependent nitrite reductase nirA YP_003031533.1 1727333 R 478434 CDS YP_003031534.1 253798533 8163449 1729437..1729994 1 NC_012943.1 hypothetical protein 1729994 8163449 TBMG_01585 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031534.1 1729437 D 478434 CDS YP_003031535.1 253798534 8163450 1729991..1730455 1 NC_012943.1 resuscitation-promoting factor rpfD 1730455 8163450 TBMG_01586 Mycobacterium tuberculosis KZN 1435 resuscitation-promoting factor rpfD YP_003031535.1 1729991 D 478434 CDS YP_003031536.1 253798535 8163451 1730516..1731688 1 NC_012943.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1731688 8163451 TBMG_01587 Mycobacterium tuberculosis KZN 1435 coproporphyrinogen III oxidase YP_003031536.1 1730516 D 478434 CDS YP_003031537.1 253798536 8163452 complement(1731685..1732938) 1 NC_012943.1 hypothetical protein 1732938 8163452 TBMG_01588 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031537.1 1731685 R 478434 CDS YP_003031538.1 253798537 8163453 1733698..1735050 1 NC_012943.1 catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function; salicylate synthase MbtI 1735050 8163453 TBMG_01589 Mycobacterium tuberculosis KZN 1435 salicylate synthase MbtI YP_003031538.1 1733698 D 478434 CDS YP_003031539.1 253798538 8163454 complement(1735054..1736037) 1 NC_012943.1 acetyl hydrolase mbtJ 1736037 8163454 TBMG_01590 Mycobacterium tuberculosis KZN 1435 acetyl hydrolase mbtJ YP_003031539.1 1735054 R 478434 CDS YP_003031540.1 253798539 8163455 complement(1736070..1737767) 1 NC_012943.1 bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase mbtA 1737767 8163455 TBMG_01591 Mycobacterium tuberculosis KZN 1435 bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase mbtA YP_003031540.1 1736070 R 478434 CDS YP_003031541.1 253798540 8163456 1737866..1742110 1 NC_012943.1 phenyloxazoline synthase mbtB 1742110 8163456 TBMG_01592 Mycobacterium tuberculosis KZN 1435 phenyloxazoline synthase mbtB YP_003031541.1 1737866 D 478434 CDS YP_003031542.1 253798541 8163457 1742100..1743434 1 NC_012943.1 polyketide synthase 1743434 8163457 TBMG_01593 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003031542.1 1742100 D 478434 CDS YP_003031543.1 253798542 8163458 1743434..1746448 1 NC_012943.1 polyketide synthase 1746448 8163458 TBMG_01594 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003031543.1 1743434 D 478434 CDS YP_003031544.1 253798543 8163459 1746441..1751636 1 NC_012943.1 peptide synthetase mbtE 1751636 8163459 TBMG_01595 Mycobacterium tuberculosis KZN 1435 peptide synthetase mbtE YP_003031544.1 1746441 D 478434 CDS YP_003031545.1 253798544 8163460 1751618..1756003 1 NC_012943.1 peptide synthetase mbtF 1756003 8163460 TBMG_01596 Mycobacterium tuberculosis KZN 1435 peptide synthetase mbtF YP_003031545.1 1751618 D 478434 CDS YP_003031546.1 253798545 8162664 1756000..1757295 1 NC_012943.1 lysine-N-oxygenase mbtG 1757295 8162664 TBMG_01597 Mycobacterium tuberculosis KZN 1435 lysine-N-oxygenase mbtG YP_003031546.1 1756000 D 478434 CDS YP_003031547.1 253798546 8162665 1757273..1757488 1 NC_012943.1 hypothetical protein 1757488 8162665 TBMG_01598 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031547.1 1757273 D 478434 CDS YP_003031548.1 253798547 8162666 1757588..1758094 1 NC_012943.1 low molecular weight protein antigen cfp2 1758094 8162666 TBMG_01599 Mycobacterium tuberculosis KZN 1435 low molecular weight protein antigen cfp2 YP_003031548.1 1757588 D 478434 CDS YP_003031549.1 253798548 8162667 complement(1758121..1758438) 1 NC_012943.1 hypothetical protein 1758438 8162667 TBMG_01600 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031549.1 1758121 R 478434 CDS YP_003031550.1 253798549 8162668 1758610..1759641 1 NC_012943.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1759641 hrcA 8162668 hrcA Mycobacterium tuberculosis KZN 1435 heat-inducible transcription repressor YP_003031550.1 1758610 D 478434 CDS YP_003031551.1 253798550 8162669 1759716..1760864 1 NC_012943.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 1760864 8162669 TBMG_01602 Mycobacterium tuberculosis KZN 1435 molecular chaperone DnaJ YP_003031551.1 1759716 D 478434 CDS YP_003031552.1 253798551 8162670 1760878..1761666 1 NC_012943.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1761666 8162670 TBMG_01603 Mycobacterium tuberculosis KZN 1435 16S ribosomal RNA methyltransferase RsmE YP_003031552.1 1760878 D 478434 CDS YP_003031553.1 253798552 8162671 complement(1761765..1762052) 1 NC_012943.1 PE-PGRS family protein 1762052 8162671 TBMG_01604 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031553.1 1761765 R 478434 CDS YP_003031554.1 253798553 8162672 1762145..1763458 1 NC_012943.1 hypothetical protein 1763458 8162672 TBMG_01605 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031554.1 1762145 D 478434 CDS YP_003031555.1 253798554 8162673 1763729..1764787 1 NC_012943.1 phosphate starvation-inducible protein phoH1 1764787 8162673 TBMG_04025 Mycobacterium tuberculosis KZN 1435 phosphate starvation-inducible protein phoH1 YP_003031555.1 1763729 D 478434 CDS YP_003031556.1 253798555 8162674 1764791..1765339 1 NC_012943.1 metalloprotease 1765339 8162674 TBMG_01608 Mycobacterium tuberculosis KZN 1435 metalloprotease YP_003031556.1 1764791 D 478434 CDS YP_003031557.1 253798556 8162675 1765336..1766643 1 NC_012943.1 hypothetical protein 1766643 8162675 TBMG_01609 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031557.1 1765336 D 478434 CDS YP_003031558.1 253798557 8162676 1766615..1766956 1 NC_012943.1 hypothetical protein 1766956 8162676 TBMG_01610 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031558.1 1766615 D 478434 CDS YP_003031559.1 253798558 8162677 1767030..1767932 1 NC_012943.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1767932 era 8162677 era Mycobacterium tuberculosis KZN 1435 GTP-binding protein Era YP_003031559.1 1767030 D 478434 CDS YP_003031560.1 253798559 8162678 complement(1767929..1769383) 1 NC_012943.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1769383 8162678 TBMG_01612 Mycobacterium tuberculosis KZN 1435 amidase YP_003031560.1 1767929 R 478434 CDS YP_003031561.1 253798560 8162679 1769445..1770242 1 NC_012943.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1770242 recO 8162679 recO Mycobacterium tuberculosis KZN 1435 DNA repair protein RecO YP_003031561.1 1769445 D 478434 CDS YP_003031562.1 253798561 8162680 1770235..1771125 1 NC_012943.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 1771125 8162680 TBMG_01614 Mycobacterium tuberculosis KZN 1435 UDP pyrophosphate synthase YP_003031562.1 1770235 D 478434 CDS YP_003031563.1 253798562 8162681 1771125..1771553 1 NC_012943.1 hypothetical protein 1771553 8162681 TBMG_01615 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031563.1 1771125 D 478434 CDS YP_003031564.1 253798563 8162682 complement(1771661..1772053) 1 NC_012943.1 ferric uptake regulation protein furB 1772053 8162682 TBMG_01616 Mycobacterium tuberculosis KZN 1435 ferric uptake regulation protein furB YP_003031564.1 1771661 R 478434 CDS YP_003031565.1 253798564 8162683 complement(1772050..1772457) 1 NC_012943.1 transcriptional regulator, arsR-family 1772457 8162683 TBMG_01617 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, arsR-family YP_003031565.1 1772050 R 478434 CDS YP_003031566.1 253798565 8162684 1772639..1774030 1 NC_012943.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1774030 8162684 TBMG_01618 Mycobacterium tuberculosis KZN 1435 glycyl-tRNA synthetase YP_003031566.1 1772639 D 478434 CDS YP_003031567.1 253798566 8162685 1774168..1776015 1 NC_012943.1 PPE family protein 1776015 8162685 TBMG_01619 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031567.1 1774168 D 478434 CDS YP_003031568.1 253798567 8162686 1776753..1778621 1 NC_012943.1 PPE family protein 1778621 8162686 TBMG_01620 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031568.1 1776753 D 478434 CDS YP_003031569.1 253798568 8162687 1779051..1780226 1 NC_012943.1 PPE family protein 1780226 8162687 TBMG_01621 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031569.1 1779051 D 478434 CDS YP_003031570.1 253798569 8162688 1780315..1780614 1 NC_012943.1 hypothetical protein 1780614 8162688 TBMG_01622 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031570.1 1780315 D 478434 CDS YP_003031571.1 253798570 8162689 1780629..1780913 1 NC_012943.1 hypothetical protein 1780913 8162689 TBMG_01623 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031571.1 1780629 D 478434 CDS YP_003031572.1 253798571 8162690 1781168..1781494 1 NC_012943.1 transposase 1781494 8162690 TBMG_01624 Mycobacterium tuberculosis KZN 1435 transposase YP_003031572.1 1781168 D 478434 CDS YP_003031573.1 253798572 8162691 1781545..1782429 1 NC_012943.1 transposase 1782429 8162691 TBMG_01625 Mycobacterium tuberculosis KZN 1435 transposase YP_003031573.1 1781545 D 478434 CDS YP_003031574.1 253798573 8162692 1782493..1783668 1 NC_012943.1 PPE family protein 1783668 8162692 TBMG_01626 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031574.1 1782493 D 478434 CDS YP_003031575.1 253798574 8162693 complement(1783799..1784026) 1 NC_012943.1 hypothetical protein 1784026 8162693 TBMG_04026 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031575.1 1783799 R 478434 CDS YP_003031576.1 253798575 8162694 1784492..1786054 1 NC_012943.1 membrane-associated phospholipase C 1 plcA 1786054 8162694 TBMG_01627 Mycobacterium tuberculosis KZN 1435 membrane-associated phospholipase C 1 plcA YP_003031576.1 1784492 D 478434 CDS YP_003031577.1 253798576 8162695 1786245..1787810 1 NC_012943.1 membrane-associated phospholipase C 2 plcB 1787810 8162695 TBMG_01628 Mycobacterium tuberculosis KZN 1435 membrane-associated phospholipase C 2 plcB YP_003031577.1 1786245 D 478434 CDS YP_003031578.1 253798577 8162696 1787869..1789419 1 NC_012943.1 phospholipase C 3 plcC 1789419 8162696 TBMG_01629 Mycobacterium tuberculosis KZN 1435 phospholipase C 3 plcC YP_003031578.1 1787869 D 478434 CDS YP_003031579.1 253798578 8162697 1789635..1789937 1 NC_012943.1 hypothetical protein 1789937 8162697 TBMG_01630 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031579.1 1789635 D 478434 CDS YP_003031580.1 253798579 8162698 1790072..1790368 1 NC_012943.1 esat-6 like protein esxP 1790368 8162698 TBMG_01631 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxP YP_003031580.1 1790072 D 478434 CDS YP_003031581.1 253798580 8162699 1790419..1790703 1 NC_012943.1 esat-6 like protein esxO 1790703 8162699 TBMG_01632 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxO YP_003031581.1 1790419 D 478434 CDS YP_003031582.1 253798581 8162700 complement(1790788..1792770) 1 NC_012943.1 hypothetical protein 1792770 8162700 TBMG_01633 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031582.1 1790788 R 478434 CDS YP_003031583.1 253798582 8162701 1792839..1794134 1 NC_012943.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1794134 8162701 TBMG_01634 Mycobacterium tuberculosis KZN 1435 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_003031583.1 1792839 D 478434 CDS YP_003031584.1 253798583 8162702 1794139..1796058 1 NC_012943.1 synthesizes RNA primers at the replication forks; DNA primase 1796058 dnaG 8162702 dnaG Mycobacterium tuberculosis KZN 1435 DNA primase YP_003031584.1 1794139 D 478434 CDS YP_003031585.1 253798584 8162703 complement(1796062..1796355) 1 NC_012943.1 hypothetical protein 1796355 8162703 TBMG_01636 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031585.1 1796062 R 478434 CDS YP_003031586.1 253798585 8162704 complement(1796575..1797009) 1 NC_012943.1 hypothetical protein 1797009 8162704 TBMG_01637 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031586.1 1796575 R 478434 CDS YP_003031587.1 253798586 8162706 1797587..1798924 1 NC_012943.1 PE-PGRS family protein 1798924 8162706 TBMG_01638 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031587.1 1797587 D 478434 CDS YP_003031588.1 253798587 8162707 complement(1799010..1801898) 1 NC_012943.1 transmembrane transporter mmpL9 1801898 8162707 TBMG_01639 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL9 YP_003031588.1 1799010 R 478434 CDS YP_003031589.1 253798588 8162708 1802528..1803484 1 NC_012943.1 hypothetical protein 1803484 8162708 TBMG_01640 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031589.1 1802528 D 478434 CDS YP_003031590.1 253798589 8162709 1803604..1804722 1 NC_012943.1 hypothetical protein 1804722 8162709 TBMG_01641 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031590.1 1803604 D 478434 CDS YP_003031591.1 253798590 8162710 complement(1804786..1805754) 1 NC_012943.1 hypothetical protein 1805754 8162710 TBMG_01642 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031591.1 1804786 R 478434 CDS YP_003031592.1 253798591 8162711 complement(1806170..1806859) 1 NC_012943.1 serine acetyltransferase cysE 1806859 8162711 TBMG_01643 Mycobacterium tuberculosis KZN 1435 serine acetyltransferase cysE YP_003031592.1 1806170 R 478434 CDS YP_003031593.1 253798592 8162712 complement(1806863..1807651) 1 NC_012943.1 truncated CDS; cysteine synthase A cysK1 1807651 8162712 TBMG_01644 Mycobacterium tuberculosis KZN 1435 cysteine synthase A cysK1 YP_003031593.1 1806863 R 478434 CDS YP_003031594.1 253798593 8162713 1808271..1809884 1 NC_012943.1 membrane transporter 1809884 8162713 TBMG_01645 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003031594.1 1808271 D 478434 CDS YP_003031595.1 253798594 8162714 complement(1809838..1811484) 1 NC_012943.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1811484 8162714 TBMG_01646 Mycobacterium tuberculosis KZN 1435 malate dehydrogenase YP_003031595.1 1809838 R 478434 CDS YP_003031596.1 253798595 8162715 complement(1811514..1811852) 1 NC_012943.1 hypothetical protein 1811852 8162715 TBMG_01647 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031596.1 1811514 R 478434 CDS YP_003031597.1 253798596 8162716 complement(1811909..1812295) 1 NC_012943.1 hypothetical protein 1812295 8162716 TBMG_01648 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031597.1 1811909 R 478434 CDS YP_003031598.1 253798597 8162717 1812370..1812897 1 NC_012943.1 hypothetical protein 1812897 8162717 TBMG_01649 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031598.1 1812370 D 478434 CDS YP_003031599.1 253798598 8162718 1813131..1814678 1 NC_012943.1 nitrite extrusion protein 1 narK1 1814678 8162718 TBMG_01650 Mycobacterium tuberculosis KZN 1435 nitrite extrusion protein 1 narK1 YP_003031599.1 1813131 D 478434 CDS YP_003031600.1 253798599 8162719 complement(1814713..1815861) 1 NC_012943.1 PE family protein 1815861 8162719 TBMG_01651 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031600.1 1814713 R 478434 CDS YP_003031601.1 253798600 8162720 complement(1816113..1816604) 1 NC_012943.1 hypothetical protein 1816604 8162720 TBMG_01652 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031601.1 1816113 R 478434 CDS YP_003031602.1 253798601 8162721 1816645..1818738 1 NC_012943.1 transmembrane ATP-binding protein ABC transporter 1818738 8162721 TBMG_01653 Mycobacterium tuberculosis KZN 1435 transmembrane ATP-binding protein ABC transporter YP_003031602.1 1816645 D 478434 CDS YP_003031603.1 253798602 8162722 1818735..1819583 1 NC_012943.1 hypothetical protein 1819583 8162722 TBMG_01654 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031603.1 1818735 D 478434 CDS YP_003031604.1 253798603 8162723 complement(1819812..1820258) 1 NC_012943.1 transcriptional regulator, asnC-family 1820258 8162723 TBMG_01655 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, asnC-family YP_003031604.1 1819812 R 478434 CDS YP_003031605.1 253798604 8162724 1820323..1821231 1 NC_012943.1 hypothetical protein 1821231 8162724 TBMG_01656 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031605.1 1820323 D 478434 CDS YP_003031606.1 253798605 8162725 1821204..1821893 1 NC_012943.1 ornithine aminotransferase rocD1 1821893 8162725 TBMG_01657 Mycobacterium tuberculosis KZN 1435 ornithine aminotransferase rocD1 YP_003031606.1 1821204 D 478434 CDS YP_003031607.1 253798606 8162726 1821887..1822438 1 NC_012943.1 ornithine aminotransferase rocD2 1822438 8162726 TBMG_01658 Mycobacterium tuberculosis KZN 1435 ornithine aminotransferase rocD2 YP_003031607.1 1821887 D 478434 CDS YP_003031608.1 253798607 8162727 1822439..1823869 1 NC_012943.1 hypothetical protein 1823869 8162727 TBMG_01659 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031608.1 1822439 D 478434 CDS YP_003031609.1 253798608 8162728 1823866..1824744 1 NC_012943.1 hypothetical protein 1824744 8162728 TBMG_01660 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031609.1 1823866 D 478434 CDS YP_003031610.1 253798609 8162729 complement(1824752..1826074) 1 NC_012943.1 periplasmic sugar-binding lipoprotein uspC 1826074 8162729 TBMG_01661 Mycobacterium tuberculosis KZN 1435 periplasmic sugar-binding lipoprotein uspC YP_003031610.1 1824752 R 478434 CDS YP_003031611.1 253798610 8162730 complement(1826071..1826895) 1 NC_012943.1 hypothetical protein 1826895 8162730 TBMG_01662 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031611.1 1826071 R 478434 CDS YP_003031612.1 253798611 8162731 complement(1826882..1827754) 1 NC_012943.1 hypothetical protein 1827754 8162731 TBMG_01663 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031612.1 1826882 R 478434 CDS YP_003031613.1 253798612 8162732 1827788..1829305 1 NC_012943.1 hypothetical protein 1829305 8162732 TBMG_01664 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031613.1 1827788 D 478434 CDS YP_003031614.1 253798613 8162733 1829302..1830675 1 NC_012943.1 hypothetical protein 1830675 8162733 TBMG_01665 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031614.1 1829302 D 478434 CDS YP_003031615.1 253798614 8162734 1830686..1831540 1 NC_012943.1 hypothetical protein 1831540 8162734 TBMG_01666 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031615.1 1830686 D 478434 CDS YP_003031616.1 253798615 8162735 complement(1831837..1832106) 1 NC_012943.1 hypothetical protein 1832106 8162735 TBMG_01667 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031616.1 1831837 R 478434 CDS YP_003031617.1 253798616 8162736 complement(1832184..1832780) 1 NC_012943.1 hypothetical protein 1832780 8162736 TBMG_01668 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031617.1 1832184 R 478434 CDS YP_003031618.1 253798617 8162737 complement(1832813..1833157) 1 NC_012943.1 excisionase 1833157 8162737 TBMG_01669 Mycobacterium tuberculosis KZN 1435 excisionase YP_003031618.1 1832813 R 478434 CDS YP_003031619.1 253798618 8162738 complement(1833163..1833315) 1 NC_012943.1 hypothetical protein 1833315 8162738 TBMG_04027 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031619.1 1833163 R 478434 CDS YP_003031620.1 253798619 8162739 complement(1833260..1833547) 1 NC_012943.1 hypothetical protein 1833547 8162739 TBMG_04028 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031620.1 1833260 R 478434 CDS YP_003031621.1 253798620 8162740 1834294..1834749 1 NC_012943.1 integrase 1834749 8162740 TBMG_01671 Mycobacterium tuberculosis KZN 1435 integrase YP_003031621.1 1834294 D 478434 CDS YP_003031622.1 253798621 8162742 1834845..1835168 1 NC_012943.1 hypothetical protein 1835168 8162742 TBMG_01672 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031622.1 1834845 D 478434 CDS YP_003031623.1 253798622 8162743 complement(1835115..1835447) 1 NC_012943.1 hypothetical protein 1835447 8162743 TBMG_01673 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031623.1 1835115 R 478434 CDS YP_003031624.1 253798623 8161319 complement(1835457..1836173) 1 NC_012943.1 hypothetical protein 1836173 8161319 TBMG_01674 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031624.1 1835457 R 478434 CDS YP_003031625.1 253798624 8161320 1836657..1837088 1 NC_012943.1 hypothetical protein 1837088 8161320 TBMG_01675 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031625.1 1836657 D 478434 CDS YP_003031626.1 253798625 8161321 1837173..1837364 1 NC_012943.1 hypothetical protein 1837364 8161321 TBMG_01676 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031626.1 1837173 D 478434 CDS YP_003031627.1 253798626 8161322 1837896..1838741 1 NC_012943.1 hypothetical protein 1838741 8161322 TBMG_01677 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031627.1 1837896 D 478434 CDS YP_003031628.1 253798627 8161323 complement(1838670..1839104) 1 NC_012943.1 hypothetical protein 1839104 8161323 TBMG_04029 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031628.1 1838670 R 478434 CDS YP_003031629.1 253798628 8161324 complement(1838891..1839484) 1 NC_012943.1 hypothetical protein 1839484 8161324 TBMG_04030 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031629.1 1838891 R 478434 CDS YP_003031630.1 253798629 8161325 complement(1839494..1840783) 1 NC_012943.1 hypothetical protein 1840783 8161325 TBMG_01679 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031630.1 1839494 R 478434 CDS YP_003031631.1 253798630 8161326 1841573..1842496 1 NC_012943.1 antibiotic-resistance protein 1842496 8161326 TBMG_01680 Mycobacterium tuberculosis KZN 1435 antibiotic-resistance protein YP_003031631.1 1841573 D 478434 CDS YP_003031632.1 253798631 8161327 complement(1842537..1842779) 1 NC_012943.1 hypothetical protein 1842779 8161327 TBMG_01681 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031632.1 1842537 R 478434 CDS YP_003031633.1 253798632 8161328 complement(1842885..1843544) 1 NC_012943.1 cutinase cut2 1843544 8161328 TBMG_01682 Mycobacterium tuberculosis KZN 1435 cutinase cut2 YP_003031633.1 1842885 R 478434 CDS YP_003031634.1 253798633 8161329 1843584..1844516 1 NC_012943.1 hypothetical protein 1844516 8161329 TBMG_01683 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031634.1 1843584 D 478434 CDS YP_003031635.1 253798634 8161330 1844590..1846533 1 NC_012943.1 molecular chaperone; heat shock protein 90 1846533 8161330 TBMG_01684 Mycobacterium tuberculosis KZN 1435 heat shock protein 90 YP_003031635.1 1844590 D 478434 CDS YP_003031636.1 253798635 8161331 complement(1846539..1847606) 1 NC_012943.1 hypothetical protein 1847606 8161331 TBMG_01685 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031636.1 1846539 R 478434 CDS YP_003031637.1 253798636 8161332 complement(1847702..1848154) 1 NC_012943.1 hypothetical protein 1848154 8161332 TBMG_01686 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031637.1 1847702 R 478434 CDS YP_003031638.1 253798637 8161333 complement(1848186..1849088) 1 NC_012943.1 haloalkane dehalogenase 1849088 8161333 TBMG_01687 Mycobacterium tuberculosis KZN 1435 haloalkane dehalogenase YP_003031638.1 1848186 R 478434 CDS YP_003031639.1 253798638 8161334 complement(1849182..1849820) 1 NC_012943.1 hypothetical protein 1849820 8161334 TBMG_01688 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031639.1 1849182 R 478434 CDS YP_003031640.1 253798639 8161335 complement(1850042..1851265) 1 NC_012943.1 aminotransferase 1851265 8161335 TBMG_01689 Mycobacterium tuberculosis KZN 1435 aminotransferase YP_003031640.1 1850042 R 478434 CDS YP_003031641.1 253798640 8161336 1851560..1852300 1 NC_012943.1 hypothetical protein 1852300 8161336 TBMG_01690 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031641.1 1851560 D 478434 CDS YP_003031642.1 253798641 8161337 1852339..1852563 1 NC_012943.1 hypothetical protein 1852563 8161337 TBMG_01691 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031642.1 1852339 D 478434 CDS YP_003031643.1 253798642 8161338 complement(1852564..1853418) 1 NC_012943.1 thiosulfate sulfurtransferase sseB 1853418 8161338 TBMG_01692 Mycobacterium tuberculosis KZN 1435 thiosulfate sulfurtransferase sseB YP_003031643.1 1852564 R 478434 CDS YP_003031644.1 253798643 8161339 complement(1853478..1854050) 1 NC_012943.1 hypothetical protein 1854050 8161339 TBMG_01693 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031644.1 1853478 R 478434 CDS YP_003031645.1 253798644 8161340 complement(1854135..1854917) 1 NC_012943.1 CDP-diacylglycerol pyrophosphatase 1854917 8161340 TBMG_01694 Mycobacterium tuberculosis KZN 1435 CDP-diacylglycerol pyrophosphatase YP_003031645.1 1854135 R 478434 CDS YP_003031646.1 253798645 8161341 complement(1854887..1855264) 1 NC_012943.1 hypothetical protein 1855264 8161341 TBMG_01695 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031646.1 1854887 R 478434 CDS YP_003031647.1 253798646 8161342 complement(1855261..1856889) 1 NC_012943.1 membrane transporter yjcE 1856889 8161342 TBMG_01696 Mycobacterium tuberculosis KZN 1435 membrane transporter yjcE YP_003031647.1 1855261 R 478434 CDS YP_003031648.1 253798647 8161343 1857023..1857715 1 NC_012943.1 hypothetical protein 1857715 8161343 TBMG_01697 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031648.1 1857023 D 478434 CDS YP_003031649.1 253798648 8161344 complement(1857782..1859119) 1 NC_012943.1 hypothetical protein 1859119 8161344 TBMG_01698 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031649.1 1857782 R 478434 CDS YP_003031650.1 253798649 8161345 complement(1859152..1860447) 1 NC_012943.1 esterase lipM 1860447 8161345 TBMG_01699 Mycobacterium tuberculosis KZN 1435 esterase lipM YP_003031650.1 1859152 R 478434 CDS YP_003031651.1 253798650 8161346 1860715..1861041 1 NC_012943.1 transposase 1861041 8161346 TBMG_01700 Mycobacterium tuberculosis KZN 1435 transposase YP_003031651.1 1860715 D 478434 CDS YP_003031652.1 253798651 8161347 1861092..1861976 1 NC_012943.1 transposase 1861976 8161347 TBMG_01701 Mycobacterium tuberculosis KZN 1435 transposase YP_003031652.1 1861092 D 478434 CDS YP_003031653.1 253798652 8161348 1862074..1863012 1 NC_012943.1 LysR family transcriptional regulator 1863012 8161348 TBMG_01702 Mycobacterium tuberculosis KZN 1435 LysR family transcriptional regulator YP_003031653.1 1862074 D 478434 CDS YP_003031654.1 253798653 8161349 complement(1863119..1864777) 1 NC_012943.1 phosphate-transport permease pitB 1864777 8161349 TBMG_01703 Mycobacterium tuberculosis KZN 1435 phosphate-transport permease pitB YP_003031654.1 1863119 R 478434 CDS YP_003031655.1 253798654 8161350 complement(1865011..1866390) 1 NC_012943.1 dehydrogenase 1866390 8161350 TBMG_01704 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003031655.1 1865011 R 478434 CDS YP_003031656.1 253798655 8161351 1866554..1867468 1 NC_012943.1 glycerolphosphodiesterase 1867468 8161351 TBMG_01705 Mycobacterium tuberculosis KZN 1435 glycerolphosphodiesterase YP_003031656.1 1866554 D 478434 CDS YP_003031657.1 253798656 8161352 complement(1867653..1868843) 1 NC_012943.1 cytochrome P450 121 cyp121 1868843 8161352 TBMG_01706 Mycobacterium tuberculosis KZN 1435 cytochrome P450 121 cyp121 YP_003031657.1 1867653 R 478434 CDS YP_003031658.1 253798657 8161353 complement(1868840..1869373) 1 NC_012943.1 hypothetical protein 1869373 8161353 TBMG_01707 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031658.1 1868840 R 478434 CDS YP_003031659.1 253798658 8161354 1869505..1869753 1 NC_012943.1 antitoxin 1869753 8161354 TBMG_04031 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031659.1 1869505 D 478434 CDS YP_003031660.1 253798659 8161355 1869787..1870104 1 NC_012943.1 toxin 1870104 8161355 TBMG_01708 Mycobacterium tuberculosis KZN 1435 toxin YP_003031660.1 1869787 D 478434 CDS YP_003031661.1 253798660 8161356 complement(1870161..1870490) 1 NC_012943.1 hypothetical protein 1870490 8161356 TBMG_01709 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031661.1 1870161 R 478434 CDS YP_003031662.1 253798661 8161357 complement(1870487..1870855) 1 NC_012943.1 hypothetical protein 1870855 8161357 TBMG_01710 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031662.1 1870487 R 478434 CDS YP_003031663.1 253798662 8161358 complement(1870961..1871260) 1 NC_012943.1 hypothetical protein 1871260 8161358 TBMG_01711 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031663.1 1870961 R 478434 CDS YP_003031664.1 253798663 8161359 complement(1871367..1871894) 1 NC_012943.1 hypothetical protein 1871894 8161359 TBMG_01712 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031664.1 1871367 R 478434 CDS YP_003031665.1 253798664 8161360 1871971..1872303 1 NC_012943.1 hypothetical protein 1872303 8161360 TBMG_01713 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031665.1 1871971 D 478434 CDS YP_003031666.1 253798665 8161361 1872316..1873785 1 NC_012943.1 cytochrome P450 128 cyp128 1873785 8161361 TBMG_01714 Mycobacterium tuberculosis KZN 1435 cytochrome P450 128 cyp128 YP_003031666.1 1872316 D 478434 CDS YP_003031667.1 253798666 8161362 1873782..1874948 1 NC_012943.1 hypothetical protein 1874948 8161362 TBMG_01715 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031667.1 1873782 D 478434 CDS YP_003031668.1 253798667 8161363 complement(1875202..1876488) 1 NC_012943.1 cytochrome P450 124 cyp124 1876488 8161363 TBMG_01716 Mycobacterium tuberculosis KZN 1435 cytochrome P450 124 cyp124 YP_003031668.1 1875202 R 478434 CDS YP_003031669.1 253798668 8161364 complement(1876663..1877892) 1 NC_012943.1 hypothetical protein 1877892 8161364 TBMG_01717 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031669.1 1876663 R 478434 CDS YP_003031670.1 253798669 8161365 1878242..1880020 1 NC_012943.1 hypothetical protein 1880020 8161365 TBMG_01718 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031670.1 1878242 D 478434 CDS YP_003031671.1 253798670 8161366 complement(1879998..1880951) 1 NC_012943.1 short chain dehydrogenase 1880951 8161366 TBMG_01719 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003031671.1 1879998 R 478434 CDS YP_003031672.1 253798671 8161368 1880950..1882548 1 NC_012943.1 apolipoprotein N-acyltransferase 1882548 8161368 TBMG_01720 Mycobacterium tuberculosis KZN 1435 apolipoprotein N-acyltransferase YP_003031672.1 1880950 D 478434 CDS YP_003031673.1 253798672 8161367 complement(1882625..1883263) 1 NC_012943.1 hypothetical protein 1883263 8161367 TBMG_01721 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031673.1 1882625 R 478434 CDS YP_003031674.1 253798673 8161369 complement(1883260..1884345) 1 NC_012943.1 zinc-type alcohol dehydrogenase adhE2 1884345 8161369 TBMG_01722 Mycobacterium tuberculosis KZN 1435 zinc-type alcohol dehydrogenase adhE2 YP_003031674.1 1883260 R 478434 CDS YP_003031675.1 253798674 8161370 1884693..1885754 1 NC_012943.1 transcriptional regulator 1885754 8161370 TBMG_01723 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031675.1 1884693 D 478434 CDS YP_003031676.1 253798675 8161371 1885768..1886586 1 NC_012943.1 hypothetical protein 1886586 8161371 TBMG_01724 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031676.1 1885768 D 478434 CDS YP_003031677.1 253798676 8161372 1886716..1887249 1 NC_012943.1 hypothetical protein 1887249 8161372 TBMG_01725 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031677.1 1886716 D 478434 CDS YP_003031678.1 253798677 8161373 complement(1887278..1887496) 1 NC_012943.1 hypothetical protein 1887496 8161373 TBMG_04032 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031678.1 1887278 R 478434 CDS YP_003031679.1 253798678 8161374 1887615..1888070 1 NC_012943.1 hypothetical protein 1888070 8161374 TBMG_01726 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031679.1 1887615 D 478434 CDS YP_003031680.1 253798679 8161375 complement(1888103..1888606) 1 NC_012943.1 hypothetical protein 1888606 8161375 TBMG_01727 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031680.1 1888103 R 478434 CDS YP_003031681.1 253798680 8161376 complement(1888672..1889601) 1 NC_012943.1 involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); the enzyme from Mycobacterium tuberculosis can phosphorylate a variety of amphipathic lipids; diacylglycerol kinase 1889601 8161376 TBMG_01728 Mycobacterium tuberculosis KZN 1435 diacylglycerol kinase YP_003031681.1 1888672 R 478434 CDS YP_003031682.1 253798681 8161377 complement(1889598..1891187) 1 NC_012943.1 flavoprotein 1891187 8161377 TBMG_01729 Mycobacterium tuberculosis KZN 1435 flavoprotein YP_003031682.1 1889598 R 478434 CDS YP_003031683.1 253798682 8161378 1891235..1891804 1 NC_012943.1 transcriptional regulator 1891804 8161378 TBMG_01730 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031683.1 1891235 D 478434 CDS YP_003031684.1 253798683 8161379 1891798..1893348 1 NC_012943.1 glycerol-3-phosphate dehydrogenase glpD1 1893348 8161379 TBMG_01731 Mycobacterium tuberculosis KZN 1435 glycerol-3-phosphate dehydrogenase glpD1 YP_003031684.1 1891798 D 478434 CDS YP_003031685.1 253798684 8161380 complement(1893417..1894304) 1 NC_012943.1 hypothetical protein 1894304 8161380 TBMG_01732 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031685.1 1893417 R 478434 CDS YP_003031686.1 253798685 8161381 complement(1894428..1895849) 1 NC_012943.1 acetyl/propionyl-CoA carboxylase beta subunit accD6 1895849 8161381 TBMG_01733 Mycobacterium tuberculosis KZN 1435 acetyl/propionyl-CoA carboxylase beta subunit accD6 YP_003031686.1 1894428 R 478434 CDS YP_003031687.1 253798686 8161382 complement(1895880..1897196) 1 NC_012943.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1897196 8161382 TBMG_01734 Mycobacterium tuberculosis KZN 1435 3-oxoacyl-ACP synthase YP_003031687.1 1895880 R 478434 CDS YP_003031688.1 253798687 8161383 complement(1897397..1898476) 1 NC_012943.1 truncated CDS; 3-oxoacyl-ACP synthase 1898476 8161383 TBMG_01735 Mycobacterium tuberculosis KZN 1435 3-oxoacyl-ACP synthase YP_003031688.1 1897397 R 478434 CDS YP_003031689.1 253798688 8161384 complement(1898473..1898820) 1 NC_012943.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1898820 acpP 8161384 acpP Mycobacterium tuberculosis KZN 1435 acyl carrier protein YP_003031689.1 1898473 R 478434 CDS YP_003031690.1 253798689 8161385 complement(1898896..1899804) 1 NC_012943.1 malonyl CoA-acyl carrier protein transacylase fabD 1899804 8161385 TBMG_01737 Mycobacterium tuberculosis KZN 1435 malonyl CoA-acyl carrier protein transacylase fabD YP_003031690.1 1898896 R 478434 CDS YP_003031691.1 253798690 8161386 complement(1900043..1901287) 1 NC_012943.1 hypothetical protein 1901287 8161386 TBMG_01738 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031691.1 1900043 R 478434 CDS YP_003031692.1 253798691 8161387 complement(1901347..1904139) 1 NC_012943.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1904139 aceE 8161387 aceE Mycobacterium tuberculosis KZN 1435 pyruvate dehydrogenase subunit E1 YP_003031692.1 1901347 R 478434 CDS YP_003031693.1 253798692 8161389 1904104..1904901 1 NC_012943.1 hypothetical protein 1904901 8161389 TBMG_01740 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031693.1 1904104 D 478434 CDS YP_003031694.1 253798693 8161388 1904939..1905415 1 NC_012943.1 hypothetical protein 1905415 8161388 TBMG_01741 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031694.1 1904939 D 478434 CDS YP_003031695.1 253798694 8161390 1905415..1905876 1 NC_012943.1 peroxiredoxin ahpE 1905876 8161390 TBMG_01742 Mycobacterium tuberculosis KZN 1435 peroxiredoxin ahpE YP_003031695.1 1905415 D 478434 CDS YP_003031696.1 253798695 8161392 1906004..1906240 1 NC_012943.1 hypothetical protein 1906240 8161392 TBMG_04033 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031696.1 1906004 D 478434 CDS YP_003031697.1 253798696 8161393 complement(1906335..1907150) 1 NC_012943.1 hypothetical protein 1907150 8161393 TBMG_01743 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031697.1 1906335 R 478434 CDS YP_003031698.1 253798697 8161394 1907198..1908157 1 NC_012943.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 1908157 cobD 8161394 cobD Mycobacterium tuberculosis KZN 1435 cobalamin biosynthesis protein YP_003031698.1 1907198 D 478434 CDS YP_003031699.1 253798698 8161395 complement(1908139..1908954) 1 NC_012943.1 hypothetical protein 1908954 8161395 TBMG_01745 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031699.1 1908139 R 478434 CDS YP_003031700.1 253798699 8161396 complement(1908954..1909445) 1 NC_012943.1 phosphotyrosine protein phosphatase ptpA 1909445 8161396 TBMG_01746 Mycobacterium tuberculosis KZN 1435 phosphotyrosine protein phosphatase ptpA YP_003031700.1 1908954 R 478434 CDS YP_003031701.1 253798700 8161397 complement(1909438..1910196) 1 NC_012943.1 hypothetical protein 1910196 8161397 TBMG_01747 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031701.1 1909438 R 478434 CDS YP_003031702.1 253798701 8161398 1910208..1910384 1 NC_012943.1 antitoxin 1910384 8161398 TBMG_04034 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031702.1 1910208 D 478434 CDS YP_003031703.1 253798702 8161399 1910436..1910855 1 NC_012943.1 toxin 1910855 8161399 TBMG_01748 Mycobacterium tuberculosis KZN 1435 toxin YP_003031703.1 1910436 D 478434 CDS YP_003031704.1 253798703 8161484 1910892..1911986 1 NC_012943.1 hypothetical protein 1911986 8161484 TBMG_01749 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031704.1 1910892 D 478434 CDS YP_003031705.1 253798704 8161486 1911983..1913122 1 NC_012943.1 hypothetical protein 1913122 8161486 TBMG_01750 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031705.1 1911983 D 478434 CDS YP_003031706.1 253798705 8161487 1913119..1913856 1 NC_012943.1 hypothetical protein 1913856 8161487 TBMG_01751 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031706.1 1913119 D 478434 CDS YP_003031707.1 253798706 8161488 1913853..1914947 1 NC_012943.1 bifunctional RNase H/acid phosphatase 1914947 8161488 TBMG_01752 Mycobacterium tuberculosis KZN 1435 bifunctional RNase H/acid phosphatase YP_003031707.1 1913853 D 478434 CDS YP_003031708.1 253798707 8161489 complement(1914959..1915660) 1 NC_012943.1 hypothetical protein 1915660 8161489 TBMG_01753 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031708.1 1914959 R 478434 CDS YP_003031709.1 253798708 8161490 complement(1916218..1917759) 1 NC_012943.1 hypothetical protein 1917759 8161490 TBMG_01754 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031709.1 1916218 R 478434 CDS YP_003031710.1 253798709 8161491 complement(1918004..1918849) 1 NC_012943.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1918849 panB 8161491 panB Mycobacterium tuberculosis KZN 1435 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_003031710.1 1918004 R 478434 CDS YP_003031711.1 253798710 8161492 1919568..1921130 1 NC_012943.1 exported protease 1921130 8161492 TBMG_01756 Mycobacterium tuberculosis KZN 1435 exported protease YP_003031711.1 1919568 D 478434 CDS YP_003031712.1 253798711 8161493 1921192..1922754 1 NC_012943.1 exported protease 1922754 8161493 TBMG_01757 Mycobacterium tuberculosis KZN 1435 exported protease YP_003031712.1 1921192 D 478434 CDS YP_003031713.1 253798712 8161494 1922849..1924189 1 NC_012943.1 glutamine synthetase glnA2 1924189 8161494 TBMG_01758 Mycobacterium tuberculosis KZN 1435 glutamine synthetase glnA2 YP_003031713.1 1922849 D 478434 CDS YP_003031714.1 253798713 8161495 1924238..1927222 1 NC_012943.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1927222 8161495 TBMG_01759 Mycobacterium tuberculosis KZN 1435 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_003031714.1 1924238 D 478434 CDS YP_003031715.1 253798714 8161496 complement(1927540..1928976) 1 NC_012943.1 glutamine synthetase glnA1 1928976 8161496 TBMG_01760 Mycobacterium tuberculosis KZN 1435 glutamine synthetase glnA1 YP_003031715.1 1927540 R 478434 CDS YP_003031716.1 253798715 8161497 1929175..1929597 1 NC_012943.1 hypothetical protein 1929597 8161497 TBMG_01761 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031716.1 1929175 D 478434 CDS YP_003031717.1 253798716 8161498 complement(1929604..1930356) 1 NC_012943.1 hypothetical protein 1930356 8161498 TBMG_01762 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031717.1 1929604 R 478434 CDS YP_003031718.1 253798717 8161499 complement(1930383..1931318) 1 NC_012943.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1931318 8161499 TBMG_01763 Mycobacterium tuberculosis KZN 1435 lipoyl synthase YP_003031718.1 1930383 R 478434 CDS YP_003031719.1 253798718 8161500 complement(1931315..1932007) 1 NC_012943.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1932007 8161500 TBMG_01764 Mycobacterium tuberculosis KZN 1435 lipoate-protein ligase B YP_003031719.1 1931315 R 478434 CDS YP_003031720.1 253798719 8161501 complement(1932060..1932965) 1 NC_012943.1 hypothetical protein 1932965 8161501 TBMG_01765 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031720.1 1932060 R 478434 CDS YP_003031721.1 253798720 8161502 complement(1932965..1934626) 1 NC_012943.1 dihydrolipoamide acetyltransferase 1934626 8161502 TBMG_01766 Mycobacterium tuberculosis KZN 1435 dihydrolipoamide acetyltransferase YP_003031721.1 1932965 R 478434 CDS YP_003031722.1 253798721 8161503 1934890..1936668 1 NC_012943.1 short chain dehydrogenase 1936668 8161503 TBMG_01767 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003031722.1 1934890 D 478434 CDS YP_003031723.1 253798722 8161504 complement(1936706..1938253) 1 NC_012943.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1938253 8161504 TBMG_01768 Mycobacterium tuberculosis KZN 1435 leucyl aminopeptidase YP_003031723.1 1936706 R 478434 CDS YP_003031724.1 253798723 8161505 complement(1938265..1939401) 1 NC_012943.1 hypothetical protein 1939401 8161505 TBMG_01769 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031724.1 1938265 R 478434 CDS YP_003031725.1 253798724 8161506 1939410..1940549 1 NC_012943.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1940549 gcvT 8161506 gcvT Mycobacterium tuberculosis KZN 1435 glycine cleavage system aminomethyltransferase T YP_003031725.1 1939410 D 478434 CDS YP_003031726.1 253798725 8161507 1940621..1941727 1 NC_012943.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1941727 8161507 TBMG_01771 Mycobacterium tuberculosis KZN 1435 branched-chain amino acid aminotransferase YP_003031726.1 1940621 D 478434 CDS YP_003031727.1 253798726 8161508 complement(1941653..1943191) 1 NC_012943.1 hypothetical protein 1943191 8161508 TBMG_01772 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031727.1 1941653 R 478434 CDS YP_003031728.1 253798727 8161509 complement(1943349..1944098) 1 NC_012943.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 1944098 cobS 8161509 cobS Mycobacterium tuberculosis KZN 1435 cobalamin synthase YP_003031728.1 1943349 R 478434 CDS YP_003031729.1 253798728 8161510 complement(1944095..1945180) 1 NC_012943.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1945180 cobT 8161510 cobT Mycobacterium tuberculosis KZN 1435 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_003031729.1 1944095 R 478434 CDS YP_003031730.1 253798729 8161511 complement(1945259..1945969) 1 NC_012943.1 hypothetical protein 1945969 8161511 TBMG_01775 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031730.1 1945259 R 478434 CDS YP_003031731.1 253798730 8161512 1946059..1947204 1 NC_012943.1 hypothetical protein 1947204 8161512 TBMG_01776 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031731.1 1946059 D 478434 CDS YP_003031732.1 253798731 8161513 1947304..1947660 1 NC_012943.1 hypothetical protein 1947660 8161513 TBMG_01777 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031732.1 1947304 D 478434 CDS YP_003031733.1 253798732 8161514 complement(1947668..1948360) 1 NC_012943.1 hypothetical protein 1948360 8161514 TBMG_01778 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031733.1 1947668 R 478434 CDS YP_003031734.1 253798733 8161515 1948564..1949538 1 NC_012943.1 carbohydrate kinase cbhK 1949538 8161515 TBMG_01779 Mycobacterium tuberculosis KZN 1435 carbohydrate kinase cbhK YP_003031734.1 1948564 D 478434 CDS YP_003031735.1 253798734 8161516 complement(1949636..1951594) 1 NC_012943.1 asparagine synthetase asnB 1951594 8161516 TBMG_01780 Mycobacterium tuberculosis KZN 1435 asparagine synthetase asnB YP_003031735.1 1949636 R 478434 CDS YP_003031736.1 253798735 8161517 1951840..1952931 1 NC_012943.1 transmembrane cytochrome C oxidase subunit II ctaC 1952931 8161517 TBMG_01781 Mycobacterium tuberculosis KZN 1435 transmembrane cytochrome C oxidase subunit II ctaC YP_003031736.1 1951840 D 478434 CDS YP_003031737.1 253798736 8161518 1952939..1953358 1 NC_012943.1 hypothetical protein 1953358 8161518 TBMG_01782 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031737.1 1952939 D 478434 CDS YP_003031738.1 253798737 8161519 1953544..1954443 1 NC_012943.1 hypothetical protein 1954443 8161519 TBMG_01783 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031738.1 1953544 D 478434 CDS YP_003031739.1 253798738 8161520 1954443..1955087 1 NC_012943.1 hypothetical protein 1955087 8161520 TBMG_01784 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031739.1 1954443 D 478434 CDS YP_003031740.1 253798739 8161521 complement(1955207..1956856) 1 NC_012943.1 ubiquinol-cytochrome C reductase qcrB cytochrome B subunit 1956856 8161521 TBMG_01785 Mycobacterium tuberculosis KZN 1435 ubiquinol-cytochrome C reductase qcrB cytochrome B subunit YP_003031740.1 1955207 R 478434 CDS YP_003031741.1 253798740 8161522 complement(1956853..1958142) 1 NC_012943.1 Rieske iron-sulfur protein qcrA 1958142 8161522 TBMG_01786 Mycobacterium tuberculosis KZN 1435 Rieske iron-sulfur protein qcrA YP_003031741.1 1956853 R 478434 CDS YP_003031742.1 253798741 8161523 complement(1958139..1958897) 1 NC_012943.1 ubiquinol-cytochrome C reductase qcrC cytochrome C subunit 1958897 8161523 TBMG_01787 Mycobacterium tuberculosis KZN 1435 ubiquinol-cytochrome C reductase qcrC cytochrome C subunit YP_003031742.1 1958139 R 478434 CDS YP_003031743.1 253798742 8161524 complement(1959022..1959633) 1 NC_012943.1 cytochrome C oxidase subunit III ctaE 1959633 8161524 TBMG_01788 Mycobacterium tuberculosis KZN 1435 cytochrome C oxidase subunit III ctaE YP_003031743.1 1959022 R 478434 CDS YP_003031744.1 253798743 8161525 1959791..1960903 1 NC_012943.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1960903 trpD 8161525 trpD Mycobacterium tuberculosis KZN 1435 anthranilate phosphoribosyltransferase YP_003031744.1 1959791 D 478434 CDS YP_003031745.1 253798744 8161526 complement(1960778..1962715) 1 NC_012943.1 contains 3'-5'exonuclease domain; hypothetical protein 1962715 8161526 TBMG_04035 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031745.1 1960778 R 478434 CDS YP_003031746.1 253798745 8161527 1962798..1963076 1 NC_012943.1 hypothetical protein 1963076 8161527 TBMG_01790 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031746.1 1962798 D 478434 CDS YP_003031747.1 253798746 8161528 1963238..1964419 1 NC_012943.1 hypothetical protein 1964419 8161528 TBMG_01791 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031747.1 1963238 D 478434 CDS YP_003031748.1 253798747 8161529 1964514..1965287 1 NC_012943.1 hypothetical protein 1965287 8161529 TBMG_01792 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031748.1 1964514 D 478434 CDS YP_003031749.1 253798748 8161530 1965384..1966541 1 NC_012943.1 hypothetical protein 1966541 8161530 TBMG_01793 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031749.1 1965384 D 478434 CDS YP_003031750.1 253798749 8161531 complement(1966572..1968383) 1 NC_012943.1 long-chain fatty-acid-CoA ligase fadD15 1968383 8161531 TBMG_01794 Mycobacterium tuberculosis KZN 1435 long-chain fatty-acid-CoA ligase fadD15 YP_003031750.1 1966572 R 478434 CDS YP_003031751.1 253798750 8161532 1968540..1968929 1 NC_012943.1 hypothetical protein 1968929 8161532 TBMG_01795 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031751.1 1968540 D 478434 CDS YP_003031752.1 253798751 8161533 1969034..1969468 1 NC_012943.1 hypothetical protein 1969468 8161533 TBMG_01796 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031752.1 1969034 D 478434 CDS YP_003031753.1 253798752 8161534 1969585..1970727 1 NC_012943.1 hypothetical protein 1970727 8161534 TBMG_01797 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031753.1 1969585 D 478434 CDS YP_003031754.1 253798753 8161535 1970724..1971119 1 NC_012943.1 hypothetical protein 1971119 8161535 TBMG_01798 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031754.1 1970724 D 478434 CDS YP_003031755.1 253798754 8161536 1971205..1971948 1 NC_012943.1 1-acylglycerol-3-phosphate O-acyltransferase 1971948 8161536 TBMG_01799 Mycobacterium tuberculosis KZN 1435 1-acylglycerol-3-phosphate O-acyltransferase YP_003031755.1 1971205 D 478434 CDS YP_003031756.1 253798755 8161537 complement(1971949..1973232) 1 NC_012943.1 hypothetical protein 1973232 8161537 TBMG_01800 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031756.1 1971949 R 478434 CDS YP_003031757.1 253798756 8161538 1973269..1974207 1 NC_012943.1 hypothetical protein 1974207 8161538 TBMG_01801 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031757.1 1973269 D 478434 CDS YP_003031758.1 253798757 8161539 1974217..1974723 1 NC_012943.1 hypothetical protein 1974723 8161539 TBMG_01802 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031758.1 1974217 D 478434 CDS YP_003031759.1 253798758 8161540 1974814..1976202 1 NC_012943.1 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase 1976202 8161540 TBMG_01803 Mycobacterium tuberculosis KZN 1435 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase YP_003031759.1 1974814 D 478434 CDS YP_003031760.1 253798759 8161541 1976470..1976652 1 NC_012943.1 hypothetical protein 1976652 8161541 TBMG_01804 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031760.1 1976470 D 478434 CDS YP_003031761.1 253798760 8161542 1976586..1977251 1 NC_012943.1 transposase 1977251 8161542 TBMG_01805 Mycobacterium tuberculosis KZN 1435 transposase YP_003031761.1 1976586 D 478434 CDS YP_003031762.1 253798761 8161543 complement(1977393..1978592) 1 NC_012943.1 Ser/Thr protein kinase 1978592 8161543 TBMG_01806 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003031762.1 1977393 R 478434 CDS YP_003031763.1 253798762 8161544 1978647..1979087 1 NC_012943.1 hypothetical protein 1979087 8161544 TBMG_01807 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031763.1 1978647 D 478434 CDS YP_003031764.1 253798763 8161545 complement(1979074..1980624) 1 NC_012943.1 hypothetical protein 1980624 8161545 TBMG_01808 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031764.1 1979074 R 478434 CDS YP_003031765.1 253798764 8161546 complement(1980628..1981686) 1 NC_012943.1 geranylgeranyl pyrophosphate synthetase idsA2 1981686 8161546 TBMG_01809 Mycobacterium tuberculosis KZN 1435 geranylgeranyl pyrophosphate synthetase idsA2 YP_003031765.1 1980628 R 478434 CDS YP_003031766.1 253798765 8161547 1981979..1982902 1 NC_012943.1 hypothetical protein 1982902 8161547 TBMG_01810 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031766.1 1981979 D 478434 CDS YP_003031767.1 253798766 8161548 complement(1982899..1983582) 1 NC_012943.1 hypothetical protein 1983582 8161548 TBMG_01811 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031767.1 1982899 R 478434 CDS YP_003031768.1 253798767 8161549 complement(1983678..1984298) 1 NC_012943.1 hypothetical protein 1984298 8161549 TBMG_01812 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031768.1 1983678 R 478434 CDS YP_003031769.1 253798768 8161550 1984564..1984968 1 NC_012943.1 hypothetical protein 1984968 8161550 TBMG_01813 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031769.1 1984564 D 478434 CDS YP_003031770.1 253798769 8161551 1985317..1985748 1 NC_012943.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1985748 8161551 TBMG_01814 Mycobacterium tuberculosis KZN 1435 cell division protein MraZ YP_003031770.1 1985317 D 478434 CDS YP_003031771.1 253798770 8161552 1985750..1986940 1 NC_012943.1 S-adenosyl-methyltransferase MraW 1986940 mraW 8161552 mraW Mycobacterium tuberculosis KZN 1435 S-adenosyl-methyltransferase MraW YP_003031771.1 1985750 D 478434 CDS YP_003031772.1 253798771 8161553 1986937..1988091 1 NC_012943.1 hypothetical protein 1988091 8161553 TBMG_01816 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031772.1 1986937 D 478434 CDS YP_003031773.1 253798772 8161554 1988088..1990127 1 NC_012943.1 hypothetical protein 1990127 8161554 TBMG_01817 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031773.1 1988088 D 478434 CDS YP_003031774.1 253798773 8161555 1990337..1991935 1 NC_012943.1 PE-PGRS family protein 1991935 8161555 TBMG_04036 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031774.1 1990337 D 478434 CDS YP_003031775.1 253798774 8161556 1992038..1992904 1 NC_012943.1 hypothetical protein 1992904 8161556 TBMG_01820 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031775.1 1992038 D 478434 CDS YP_003031776.1 253798775 8161557 1993172..1993513 1 NC_012943.1 hypothetical protein 1993513 8161557 TBMG_01821 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031776.1 1993172 D 478434 CDS YP_003031777.1 253798776 8161558 1993510..1994544 1 NC_012943.1 hypothetical protein 1994544 8161558 TBMG_01822 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031777.1 1993510 D 478434 CDS YP_003031778.1 253798777 8161559 1994567..1996174 1 NC_012943.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1996174 murE 8161559 murE Mycobacterium tuberculosis KZN 1435 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_003031778.1 1994567 D 478434 CDS YP_003031779.1 253798778 8161560 1996171..1997703 1 NC_012943.1 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 1997703 8161560 TBMG_01824 Mycobacterium tuberculosis KZN 1435 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF YP_003031779.1 1996171 D 478434 CDS YP_003031780.1 253798779 8161561 1997700..1998779 1 NC_012943.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1998779 mraY 8161561 mraY Mycobacterium tuberculosis KZN 1435 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_003031780.1 1997700 D 478434 CDS YP_003031781.1 253798780 8161562 1998772..2000241 1 NC_012943.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 2000241 murD 8161562 murD Mycobacterium tuberculosis KZN 1435 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_003031781.1 1998772 D 478434 CDS YP_003031782.1 253798781 8161563 2000253..2001827 1 NC_012943.1 cell division protein ftsW 2001827 8161563 TBMG_01827 Mycobacterium tuberculosis KZN 1435 cell division protein ftsW YP_003031782.1 2000253 D 478434 CDS YP_003031783.1 253798782 8161564 2001824..2003056 1 NC_012943.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 2003056 murG 8161564 murG Mycobacterium tuberculosis KZN 1435 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_003031783.1 2001824 D 478434 CDS YP_003031784.1 253798783 8161565 2003053..2004537 1 NC_012943.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2004537 murC 8161565 murC Mycobacterium tuberculosis KZN 1435 UDP-N-acetylmuramate--L-alanine ligase YP_003031784.1 2003053 D 478434 CDS YP_003031785.1 253798784 8161566 2004534..2005478 1 NC_012943.1 cell division protein ftsQ 2005478 8161566 TBMG_01830 Mycobacterium tuberculosis KZN 1435 cell division protein ftsQ YP_003031785.1 2004534 D 478434 CDS YP_003031786.1 253798785 8161567 2005651..2006790 1 NC_012943.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2006790 8161567 TBMG_01831 Mycobacterium tuberculosis KZN 1435 cell division protein FtsZ YP_003031786.1 2005651 D 478434 CDS YP_003031787.1 253798786 8161649 2006801..2007553 1 NC_012943.1 hypothetical protein 2007553 8161649 TBMG_01832 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031787.1 2006801 D 478434 CDS YP_003031788.1 253798787 8161650 2007550..2008335 1 NC_012943.1 hypothetical protein 2008335 8161650 TBMG_01833 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031788.1 2007550 D 478434 CDS YP_003031789.1 253798788 8161651 2008332..2009057 1 NC_012943.1 hypothetical protein 2009057 8161651 TBMG_01834 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031789.1 2008332 D 478434 CDS YP_003031790.1 253798789 8161652 2009219..2009509 1 NC_012943.1 hypothetical protein 2009509 8161652 TBMG_01835 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031790.1 2009219 D 478434 CDS YP_003031791.1 253798790 8161653 2009777..2010559 1 NC_012943.1 hypothetical protein 2010559 8161653 TBMG_01836 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031791.1 2009777 D 478434 CDS YP_003031792.1 253798791 8161654 2010654..2011010 1 NC_012943.1 hypothetical protein 2011010 8161654 TBMG_01837 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031792.1 2010654 D 478434 CDS YP_003031793.1 253798792 8161655 complement(2011140..2012198) 1 NC_012943.1 hypothetical protein 2012198 8161655 TBMG_01838 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031793.1 2011140 R 478434 CDS YP_003031794.1 253798793 8161656 2012453..2012668 1 NC_012943.1 toxin 2012668 8161656 TBMG_01839 Mycobacterium tuberculosis KZN 1435 toxin YP_003031794.1 2012453 D 478434 CDS YP_003031795.1 253798794 8161657 2012665..2012982 1 NC_012943.1 toxin 2012982 8161657 TBMG_01840 Mycobacterium tuberculosis KZN 1435 toxin YP_003031795.1 2012665 D 478434 CDS YP_003031796.1 253798795 8161659 2013389..2014741 1 NC_012943.1 hypothetical protein 2014741 8161659 TBMG_01841 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031796.1 2013389 D 478434 CDS YP_003031797.1 253798796 8161660 2014789..2015319 1 NC_012943.1 hypothetical protein 2015319 8161660 TBMG_01842 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031797.1 2014789 D 478434 CDS YP_003031798.1 253798797 8161661 complement(2015324..2016397) 1 NC_012943.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2016397 8161661 TBMG_01843 Mycobacterium tuberculosis KZN 1435 dihydroorotate dehydrogenase 2 YP_003031798.1 2015324 R 478434 CDS YP_003031799.1 253798798 8161662 complement(2016433..2016714) 1 NC_012943.1 hypothetical protein 2016714 8161662 TBMG_04037 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031799.1 2016433 R 478434 CDS YP_003031800.1 253798799 8161663 complement(2016711..2017787) 1 NC_012943.1 hypothetical protein 2017787 8161663 TBMG_04038 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031800.1 2016711 R 478434 CDS YP_003031801.1 253798800 8161664 2017802..2018215 1 NC_012943.1 hypothetical protein 2018215 8161664 TBMG_01844 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031801.1 2017802 D 478434 CDS YP_003031802.1 253798801 8161665 2018279..2019109 1 NC_012943.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 2019109 8161665 TBMG_01845 Mycobacterium tuberculosis KZN 1435 UDP pyrophosphate phosphatase YP_003031802.1 2018279 D 478434 CDS YP_003031803.1 253798802 8161666 2019106..2019816 1 NC_012943.1 hypothetical protein 2019816 8161666 TBMG_01846 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031803.1 2019106 D 478434 CDS YP_003031804.1 253798803 8161667 2019880..2020467 1 NC_012943.1 hypothetical protein 2020467 8161667 TBMG_01847 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031804.1 2019880 D 478434 CDS YP_003031805.1 253798804 8161668 2020478..2021266 1 NC_012943.1 hypothetical protein 2021266 8161668 TBMG_01848 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031805.1 2020478 D 478434 CDS YP_003031806.1 253798805 8161669 complement(2021476..2021706) 1 NC_012943.1 hypothetical protein 2021706 8161669 TBMG_01849 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031806.1 2021476 R 478434 CDS YP_003031807.1 253798806 8161670 2021797..2022600 1 NC_012943.1 monophosphatase cysQ 2022600 8161670 TBMG_01850 Mycobacterium tuberculosis KZN 1435 monophosphatase cysQ YP_003031807.1 2021797 D 478434 CDS YP_003031808.1 253798807 8161671 2022658..2023902 1 NC_012943.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2023902 8161671 TBMG_01851 Mycobacterium tuberculosis KZN 1435 cysteinyl-tRNA synthetase YP_003031808.1 2022658 D 478434 CDS YP_003031809.1 253798808 8161672 2023928..2024809 1 NC_012943.1 short chain dehydrogenase 2024809 8161672 TBMG_04039 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003031809.1 2023928 D 478434 CDS YP_003031810.1 253798809 8161673 complement(2024829..2025032) 1 NC_012943.1 hypothetical protein 2025032 8161673 TBMG_01852 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031810.1 2024829 R 478434 CDS YP_003031811.1 253798810 8161674 complement(2025032..2026501) 1 NC_012943.1 L-asparagine permease ansP1 2026501 8161674 TBMG_01853 Mycobacterium tuberculosis KZN 1435 L-asparagine permease ansP1 YP_003031811.1 2025032 R 478434 CDS YP_003031812.1 253798811 8161675 2026882..2027148 1 NC_012943.1 PE family protein 2027148 8161675 TBMG_04040 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031812.1 2026882 D 478434 CDS YP_003031813.1 253798812 8161676 2027145..2027915 1 NC_012943.1 PE-PGRS family protein 2027915 8161676 TBMG_04041 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031813.1 2027145 D 478434 CDS YP_003031814.1 253798813 8161677 complement(2027946..2028824) 1 NC_012943.1 hypothetical protein 2028824 8161677 TBMG_01855 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031814.1 2027946 R 478434 CDS YP_003031815.1 253798814 8161678 2029050..2032628 1 NC_012943.1 5-methyltetrahydrofolate--homocysteine methyltransferase 2032628 8161678 TBMG_01856 Mycobacterium tuberculosis KZN 1435 5-methyltetrahydrofolate--homocysteine methyltransferase YP_003031815.1 2029050 D 478434 CDS YP_003031816.1 253798815 8161679 complement(2032554..2034044) 1 NC_012943.1 PPE family protein 2034044 8161679 TBMG_01857 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031816.1 2032554 R 478434 CDS YP_003031817.1 253798816 8161680 2034171..2034452 1 NC_012943.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2034452 hisE 8161680 hisE Mycobacterium tuberculosis KZN 1435 phosphoribosyl-ATP pyrophosphatase YP_003031817.1 2034171 D 478434 CDS YP_003031818.1 253798817 8161681 2034455..2035309 1 NC_012943.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2035309 hisG 8161681 hisG Mycobacterium tuberculosis KZN 1435 ATP phosphoribosyltransferase YP_003031818.1 2034455 D 478434 CDS YP_003031819.1 253798818 8161682 2035355..2035870 1 NC_012943.1 hypothetical protein 2035870 8161682 TBMG_01860 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031819.1 2035355 D 478434 CDS YP_003031820.1 253798819 8161683 complement(2035893..2036729) 1 NC_012943.1 hypothetical protein 2036729 8161683 TBMG_01861 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031820.1 2035893 R 478434 CDS YP_003031821.1 253798820 8161684 2036803..2037645 1 NC_012943.1 RNA methyltransferase 2037645 8161684 TBMG_01862 Mycobacterium tuberculosis KZN 1435 RNA methyltransferase YP_003031821.1 2036803 D 478434 CDS YP_003031822.1 253798821 8161685 complement(2037674..2037967) 1 NC_012943.1 hypothetical protein 2037967 8161685 TBMG_01863 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031822.1 2037674 R 478434 CDS YP_003031823.1 253798822 8161686 complement(2037975..2038544) 1 NC_012943.1 hypothetical protein 2038544 8161686 TBMG_01864 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031823.1 2037975 R 478434 CDS YP_003031824.1 253798823 8161687 2038825..2040654 1 NC_012943.1 ATPase 2040654 8161687 TBMG_01865 Mycobacterium tuberculosis KZN 1435 ATPase YP_003031824.1 2038825 D 478434 CDS YP_003031825.1 253798824 8161688 complement(2040658..2041299) 1 NC_012943.1 hypothetical protein 2041299 8161688 TBMG_01866 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031825.1 2040658 R 478434 CDS YP_003031826.1 253798825 8161689 complement(2041292..2042485) 1 NC_012943.1 hypothetical protein 2042485 8161689 TBMG_01867 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031826.1 2041292 R 478434 CDS YP_003031827.1 253798826 8161690 2042573..2044438 1 NC_012943.1 hypothetical protein 2044438 8161690 TBMG_01868 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031827.1 2042573 D 478434 CDS YP_003031828.1 253798827 8161691 2044530..2044745 1 NC_012943.1 hypothetical protein 2044745 8161691 TBMG_01869 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031828.1 2044530 D 478434 CDS YP_003031829.1 253798828 8161692 2044742..2045617 1 NC_012943.1 proteasome beta subunit prcB 2045617 8161692 TBMG_01870 Mycobacterium tuberculosis KZN 1435 proteasome beta subunit prcB YP_003031829.1 2044742 D 478434 CDS YP_003031830.1 253798829 8161693 2045614..2046360 1 NC_012943.1 proteasome alpha subunit prcA 2046360 8161693 TBMG_01871 Mycobacterium tuberculosis KZN 1435 proteasome alpha subunit prcA YP_003031830.1 2045614 D 478434 CDS YP_003031831.1 253798830 8161694 complement(2046900..2047631) 1 NC_012943.1 PPE family protein 2047631 8161694 TBMG_01872 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003031831.1 2046900 R 478434 CDS YP_003031832.1 253798831 8161695 complement(2047687..2047983) 1 NC_012943.1 PE family protein 2047983 8161695 TBMG_01873 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031832.1 2047687 R 478434 CDS YP_003031833.1 253798832 8161696 2048187..2048513 1 NC_012943.1 transposase 2048513 8161696 TBMG_01874 Mycobacterium tuberculosis KZN 1435 transposase YP_003031833.1 2048187 D 478434 CDS YP_003031834.1 253798833 8161697 2048564..2049448 1 NC_012943.1 transposase 2049448 8161697 TBMG_04042 Mycobacterium tuberculosis KZN 1435 transposase YP_003031834.1 2048564 D 478434 CDS YP_003031835.1 253798834 8161698 2049858..2050184 1 NC_012943.1 transposase 2050184 8161698 TBMG_04043 Mycobacterium tuberculosis KZN 1435 transposase YP_003031835.1 2049858 D 478434 CDS YP_003031836.1 253798835 8161699 2050235..2051119 1 NC_012943.1 transposase 2051119 8161699 TBMG_04044 Mycobacterium tuberculosis KZN 1435 transposase YP_003031836.1 2050235 D 478434 CDS YP_003031837.1 253798836 8161700 2051607..2051903 1 NC_012943.1 hypothetical protein 2051903 8161700 TBMG_01877 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031837.1 2051607 D 478434 CDS YP_003031838.1 253798837 8161701 2051919..2052173 1 NC_012943.1 antitoxin 2052173 8161701 TBMG_01878 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031838.1 2051919 D 478434 CDS YP_003031839.1 253798838 8161702 2052180..2052614 1 NC_012943.1 toxin 2052614 8161702 TBMG_01879 Mycobacterium tuberculosis KZN 1435 toxin YP_003031839.1 2052180 D 478434 CDS YP_003031840.1 253798839 8161703 complement(2052593..2053426) 1 NC_012943.1 hypothetical protein 2053426 8161703 TBMG_01880 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031840.1 2052593 R 478434 CDS YP_003031841.1 253798840 8161704 complement(2053419..2055968) 1 NC_012943.1 helicase helZ 2055968 8161704 TBMG_01881 Mycobacterium tuberculosis KZN 1435 helicase helZ YP_003031841.1 2053419 R 478434 CDS YP_003031842.1 253798841 8161705 complement(2056579..2058231) 1 NC_012943.1 hypothetical protein 2058231 8161705 TBMG_01882 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031842.1 2056579 R 478434 CDS YP_003031843.1 253798842 8161706 2058414..2058713 1 NC_012943.1 PE family protein 2058713 8161706 TBMG_01883 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003031843.1 2058414 D 478434 CDS YP_003031844.1 253798843 8161707 2058719..2059888 1 NC_012943.1 PE-PGRS family protein 2059888 8161707 TBMG_01884 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031844.1 2058719 D 478434 CDS YP_003031845.1 253798844 8161708 2059940..2061298 1 NC_012943.1 hypothetical protein 2061298 8161708 TBMG_01885 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031845.1 2059940 D 478434 CDS YP_003031846.1 253798845 8161709 2061307..2062305 1 NC_012943.1 hypothetical protein 2062305 8161709 TBMG_01886 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031846.1 2061307 D 478434 CDS YP_003031847.1 253798846 8161710 2062302..2063252 1 NC_012943.1 hypothetical protein 2063252 8161710 TBMG_01887 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031847.1 2062302 D 478434 CDS YP_003031848.1 253798847 8161711 2063224..2063571 1 NC_012943.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 2063571 tatA 8161711 tatA Mycobacterium tuberculosis KZN 1435 twin arginine translocase protein A YP_003031848.1 2063224 D 478434 CDS YP_003031849.1 253798848 8161712 2063588..2064514 1 NC_012943.1 hypothetical protein 2064514 8161712 TBMG_01889 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031849.1 2063588 D 478434 CDS YP_003031850.1 253798849 8161713 2064631..2067351 1 NC_012943.1 ATP-dependent DNA helicase helY 2067351 8161713 TBMG_01890 Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA helicase helY YP_003031850.1 2064631 D 478434 CDS YP_003031851.1 253798850 8161714 2067393..2068127 1 NC_012943.1 hypothetical protein 2068127 8161714 TBMG_01891 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031851.1 2067393 D 478434 CDS YP_003031852.1 253798851 8161715 complement(2068131..2069312) 1 NC_012943.1 5'-3' exonuclease 2069312 8161715 TBMG_01892 Mycobacterium tuberculosis KZN 1435 5'-3' exonuclease YP_003031852.1 2068131 R 478434 CDS YP_003031853.1 253798852 8161716 2069361..2070488 1 NC_012943.1 dipeptidase pepE 2070488 8161716 TBMG_01893 Mycobacterium tuberculosis KZN 1435 dipeptidase pepE YP_003031853.1 2069361 D 478434 CDS YP_003031854.1 253798853 8161717 complement(2070505..2072274) 1 NC_012943.1 Ser/Thr protein kinase 2072274 8161717 TBMG_01894 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003031854.1 2070505 R 478434 CDS YP_003031855.1 253798854 8161718 complement(2072461..2072691) 1 NC_012943.1 transposase 2072691 8161718 TBMG_04045 Mycobacterium tuberculosis KZN 1435 transposase YP_003031855.1 2072461 R 478434 CDS YP_003031856.1 253798855 8161719 complement(2072769..2073374) 1 NC_012943.1 transposase 2073374 8161719 TBMG_01895 Mycobacterium tuberculosis KZN 1435 transposase YP_003031856.1 2072769 R 478434 CDS YP_003031857.1 253798856 8161720 complement(2073353..2073658) 1 NC_012943.1 transposase 2073658 8161720 TBMG_01896 Mycobacterium tuberculosis KZN 1435 transposase YP_003031857.1 2073353 R 478434 CDS YP_003031858.1 253798857 8161721 complement(2073741..2074877) 1 NC_012943.1 hypothetical protein 2074877 8161721 TBMG_01897 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031858.1 2073741 R 478434 CDS YP_003031859.1 253798858 8161722 complement(2074870..2075814) 1 NC_012943.1 hypothetical protein 2075814 8161722 TBMG_01898 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031859.1 2074870 R 478434 CDS YP_003031860.1 253798859 8161723 complement(2075811..2077976) 1 NC_012943.1 hypothetical protein 2077976 8161723 TBMG_01899 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031860.1 2075811 R 478434 CDS YP_003031861.1 253798860 8161724 2078172..2078645 1 NC_012943.1 hypothetical protein 2078645 8161724 TBMG_01900 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031861.1 2078172 D 478434 CDS YP_003031862.1 253798861 8161725 complement(2078841..2079404) 1 NC_012943.1 hypothetical protein 2079404 8161725 TBMG_01901 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031862.1 2078841 R 478434 CDS YP_003031863.1 253798862 8161726 complement(2079385..2081355) 1 NC_012943.1 hypothetical protein 2081355 8161726 TBMG_01902 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031863.1 2079385 R 478434 CDS YP_003031864.1 253798863 8161727 complement(2081337..2081651) 1 NC_012943.1 hypothetical protein 2081651 8161727 TBMG_04046 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031864.1 2081337 R 478434 CDS YP_003031865.1 253798864 8161728 2081688..2081858 1 NC_012943.1 hypothetical protein 2081858 8161728 TBMG_01903 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031865.1 2081688 D 478434 CDS YP_003031866.1 253798865 8161729 2082116..2082415 1 NC_012943.1 hypothetical protein 2082415 8161729 TBMG_01904 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031866.1 2082116 D 478434 CDS YP_003031867.1 253798866 8161318 2082416..2083387 1 NC_012943.1 hypothetical protein 2083387 8161318 TBMG_01905 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031867.1 2082416 D 478434 CDS YP_003031868.1 253798867 8163625 2083422..2083673 1 NC_012943.1 hypothetical protein 2083673 8163625 TBMG_04047 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031868.1 2083422 D 478434 CDS YP_003031869.1 253798868 8163626 2083831..2085294 1 NC_012943.1 hypothetical protein 2085294 8163626 TBMG_01906 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031869.1 2083831 D 478434 CDS YP_003031870.1 253798869 8163627 complement(2085304..2085717) 1 NC_012943.1 hypothetical protein 2085717 8163627 TBMG_01907 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031870.1 2085304 R 478434 CDS YP_003031871.1 253798870 8163628 2085747..2086496 1 NC_012943.1 short-chain type dehydrogenase 2086496 8163628 TBMG_01908 Mycobacterium tuberculosis KZN 1435 short-chain type dehydrogenase YP_003031871.1 2085747 D 478434 CDS YP_003031872.1 253798871 8163629 2086564..2087736 1 NC_012943.1 precorrin-6y methyltransferase cobL 2087736 8163629 TBMG_01909 Mycobacterium tuberculosis KZN 1435 precorrin-6y methyltransferase cobL YP_003031872.1 2086564 D 478434 CDS YP_003031873.1 253798872 8163630 2087733..2088488 1 NC_012943.1 precorrin-4 C11-methyltransferase 2088488 8163630 TBMG_01910 Mycobacterium tuberculosis KZN 1435 precorrin-4 C11-methyltransferase YP_003031873.1 2087733 D 478434 CDS YP_003031874.1 253798873 8163631 2088485..2089219 1 NC_012943.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 2089219 8163631 TBMG_01911 Mycobacterium tuberculosis KZN 1435 cobalt-precorrin-6x reductase YP_003031874.1 2088485 D 478434 CDS YP_003031875.1 253798874 8163632 complement(2089209..2090144) 1 NC_012943.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigC 2090144 8163632 TBMG_01912 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigC YP_003031875.1 2089209 R 478434 CDS YP_003031876.1 253798875 8163634 2089901..2090824 1 NC_012943.1 class A beta-lactamase blaC 2090824 8163634 TBMG_01913 Mycobacterium tuberculosis KZN 1435 class A beta-lactamase blaC YP_003031876.1 2089901 D 478434 CDS YP_003031877.1 253798876 8163633 2090840..2092063 1 NC_012943.1 hypothetical protein 2092063 8163633 TBMG_01914 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031877.1 2090840 D 478434 CDS YP_003031878.1 253798877 8163635 complement(2092009..2093535) 1 NC_012943.1 bifunctional cobI-cobJ fusion protein 2093535 8163635 TBMG_01915 Mycobacterium tuberculosis KZN 1435 bifunctional cobI-cobJ fusion protein YP_003031878.1 2092009 R 478434 CDS YP_003031879.1 253798878 8163636 complement(2093532..2094158) 1 NC_012943.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase 2094158 cobH 8163636 cobH Mycobacterium tuberculosis KZN 1435 precorrin-8X methylmutase YP_003031879.1 2093532 R 478434 CDS YP_003031880.1 253798879 8163637 complement(2094168..2095259) 1 NC_012943.1 cobalamin biosynthesis protein cobG 2095259 8163637 TBMG_01917 Mycobacterium tuberculosis KZN 1435 cobalamin biosynthesis protein cobG YP_003031880.1 2094168 R 478434 CDS YP_003031881.1 253798880 8163638 complement(2095243..2095653) 1 NC_012943.1 toxin 2095653 8163638 TBMG_01918 Mycobacterium tuberculosis KZN 1435 toxin YP_003031881.1 2095243 R 478434 CDS YP_003031882.1 253798881 8163639 complement(2095646..2095879) 1 NC_012943.1 antitoxin 2095879 8163639 TBMG_01919 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031882.1 2095646 R 478434 CDS YP_003031883.1 253798882 8163640 2095957..2099541 1 NC_012943.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 2099541 cobN 8163640 cobN Mycobacterium tuberculosis KZN 1435 cobaltochelatase subunit CobN YP_003031883.1 2095957 D 478434 CDS YP_003031884.1 253798883 8163641 2099617..2100030 1 NC_012943.1 hypothetical protein 2100030 8163641 TBMG_01921 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031884.1 2099617 D 478434 CDS YP_003031885.1 253798884 8163642 complement(2100002..2101537) 1 NC_012943.1 hypothetical protein 2101537 8163642 TBMG_01922 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031885.1 2100002 R 478434 CDS YP_003031886.1 253798885 8163643 2101650..2101886 1 NC_012943.1 required for 70S ribosome assembly; 50S ribosomal protein L28 2101886 rpmB 8163643 rpmB Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L28 YP_003031886.1 2101650 D 478434 CDS YP_003031887.1 253798886 8163644 2101886..2102050 1 NC_012943.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2102050 rpmG 8163644 rpmG Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L33 YP_003031887.1 2101886 D 478434 CDS YP_003031888.1 253798887 8163645 2102052..2102357 1 NC_012943.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 2102357 rpsN 8163645 rpsN Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S14 YP_003031888.1 2102052 D 478434 CDS YP_003031889.1 253798888 8163646 2102358..2102624 1 NC_012943.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 2102624 8163646 TBMG_01926 Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S18 YP_003031889.1 2102358 D 478434 CDS YP_003031890.1 253798889 8163647 complement(2102873..2103586) 1 NC_012943.1 hypothetical protein 2103586 8163647 TBMG_01927 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031890.1 2102873 R 478434 CDS YP_003031891.1 253798890 8163648 2103662..2104189 1 NC_012943.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 2104189 fxsA 8163648 fxsA Mycobacterium tuberculosis KZN 1435 FxsA YP_003031891.1 2103662 D 478434 CDS YP_003031892.1 253798891 8163649 2104194..2105798 1 NC_012943.1 hypothetical protein 2105798 8163649 TBMG_01929 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031892.1 2104194 D 478434 CDS YP_003031893.1 253798892 8163650 2105791..2108580 1 NC_012943.1 polyprenol-monophosphomannose synthase ppm1 2108580 8163650 TBMG_01930 Mycobacterium tuberculosis KZN 1435 polyprenol-monophosphomannose synthase ppm1 YP_003031893.1 2105791 D 478434 CDS YP_003031894.1 253798893 8163651 complement(2108555..2108890) 1 NC_012943.1 hypothetical protein 2108890 8163651 TBMG_01931 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031894.1 2108555 R 478434 CDS YP_003031895.1 253798894 8163652 2109056..2109418 1 NC_012943.1 hypothetical protein 2109418 8163652 TBMG_01932 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031895.1 2109056 D 478434 CDS YP_003031896.1 253798895 8163653 2109725..2122183 1 NC_012943.1 hypothetical protein 2122183 8163653 TBMG_01933 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031896.1 2109725 D 478434 CDS YP_003031897.1 253798896 8163654 2122188..2124752 1 NC_012943.1 hypothetical protein 2124752 8163654 TBMG_01934 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031897.1 2122188 D 478434 CDS YP_003031898.1 253798897 8163655 complement(2124789..2125445) 1 NC_012943.1 hypothetical protein 2125445 8163655 TBMG_01935 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031898.1 2124789 R 478434 CDS YP_003031899.1 253798898 8163656 2125494..2127029 1 NC_012943.1 carboxylesterase lipT 2127029 8163656 TBMG_01936 Mycobacterium tuberculosis KZN 1435 carboxylesterase lipT YP_003031899.1 2125494 D 478434 CDS YP_003031900.1 253798899 8163657 2127082..2127432 1 NC_012943.1 hypothetical protein 2127432 8163657 TBMG_01937 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031900.1 2127082 D 478434 CDS YP_003031901.1 253798900 8163658 2127473..2128033 1 NC_012943.1 pyrazinamidase/nicotinamidas pncA 2128033 8163658 TBMG_01938 Mycobacterium tuberculosis KZN 1435 pyrazinamidase/nicotinamidas pncA YP_003031901.1 2127473 D 478434 CDS YP_003031902.1 253798901 8163659 2128033..2128830 1 NC_012943.1 hypothetical protein 2128830 8163659 TBMG_01939 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031902.1 2128033 D 478434 CDS YP_003031903.1 253798902 8163660 2128868..2130187 1 NC_012943.1 sugar-binding lipoprotein 2130187 8163660 TBMG_01940 Mycobacterium tuberculosis KZN 1435 sugar-binding lipoprotein YP_003031903.1 2128868 D 478434 CDS YP_003031904.1 253798903 8163661 2130184..2131086 1 NC_012943.1 hypothetical protein 2131086 8163661 TBMG_01941 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031904.1 2130184 D 478434 CDS YP_003031905.1 253798904 8163662 2131073..2131915 1 NC_012943.1 hypothetical protein 2131915 8163662 TBMG_01942 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031905.1 2131073 D 478434 CDS YP_003031906.1 253798905 8163663 2131918..2132991 1 NC_012943.1 sugar ABC transporter 2132991 8163663 TBMG_01943 Mycobacterium tuberculosis KZN 1435 sugar ABC transporter YP_003031906.1 2131918 D 478434 CDS YP_003031907.1 253798906 8163664 2132993..2133967 1 NC_012943.1 hypothetical protein 2133967 8163664 TBMG_01944 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031907.1 2132993 D 478434 CDS YP_003031908.1 253798907 8163665 complement(2133974..2134615) 1 NC_012943.1 hypothetical protein 2134615 8163665 TBMG_01945 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031908.1 2133974 R 478434 CDS YP_003031909.1 253798908 8163666 complement(2134612..2135100) 1 NC_012943.1 hypothetical protein 2135100 8163666 TBMG_01946 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031909.1 2134612 R 478434 CDS YP_003031910.1 253798909 8163667 complement(2135097..2135567) 1 NC_012943.1 ArsR family transcriptional regulator 2135567 8163667 TBMG_01947 Mycobacterium tuberculosis KZN 1435 ArsR family transcriptional regulator YP_003031910.1 2135097 R 478434 CDS YP_003031911.1 253798910 8163668 2135632..2136474 1 NC_012943.1 hypothetical protein 2136474 8163668 TBMG_01948 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031911.1 2135632 D 478434 CDS YP_003031912.1 253798911 8163669 complement(2136590..2137585) 1 NC_012943.1 hypothetical protein 2137585 8163669 TBMG_01949 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031912.1 2136590 R 478434 CDS YP_003031913.1 253798912 8163670 2137731..2138216 1 NC_012943.1 heat shock protein hspX 2138216 8163670 TBMG_01950 Mycobacterium tuberculosis KZN 1435 heat shock protein hspX YP_003031913.1 2137731 D 478434 CDS YP_003031914.1 253798913 8163671 2138228..2140273 1 NC_012943.1 hypothetical protein 2140273 8163671 TBMG_01951 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031914.1 2138228 D 478434 CDS YP_003031915.1 253798914 8163672 2140290..2141309 1 NC_012943.1 phosphofructokinase pfkB 2141309 8163672 TBMG_01952 Mycobacterium tuberculosis KZN 1435 phosphofructokinase pfkB YP_003031915.1 2140290 D 478434 CDS YP_003031916.1 253798915 8163673 2141306..2142145 1 NC_012943.1 hypothetical protein 2142145 8163673 TBMG_01953 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031916.1 2141306 D 478434 CDS YP_003031917.1 253798916 8163674 2142206..2143927 1 NC_012943.1 histidine kinase response regulator 2143927 8163674 TBMG_01954 Mycobacterium tuberculosis KZN 1435 histidine kinase response regulator YP_003031917.1 2142206 D 478434 CDS YP_003031918.1 253798917 8163675 2143967..2144851 1 NC_012943.1 hypothetical protein 2144851 8163675 TBMG_01955 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031918.1 2143967 D 478434 CDS YP_003031919.1 253798918 8163676 2144966..2145964 1 NC_012943.1 hypothetical protein 2145964 8163676 TBMG_01956 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031919.1 2144966 D 478434 CDS YP_003031920.1 253798919 8163677 2146474..2151294 1 NC_012943.1 helicase 2151294 8163677 TBMG_01957 Mycobacterium tuberculosis KZN 1435 helicase YP_003031920.1 2146474 D 478434 CDS YP_003031921.1 253798920 8163678 2151478..2152374 1 NC_012943.1 hypothetical protein 2152374 8163678 TBMG_01958 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031921.1 2151478 D 478434 CDS YP_003031922.1 253798921 8163679 2152769..2153446 1 NC_012943.1 hypothetical protein 2153446 8163679 TBMG_01959 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031922.1 2152769 D 478434 CDS YP_003031923.1 253798922 8163680 2153606..2153965 1 NC_012943.1 hypothetical protein 2153965 8163680 TBMG_01960 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031923.1 2153606 D 478434 CDS YP_003031924.1 253798923 8163681 2153990..2154595 1 NC_012943.1 hypothetical protein 2154595 8163681 TBMG_01961 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031924.1 2153990 D 478434 CDS YP_003031925.1 253798924 8163682 2154604..2154909 1 NC_012943.1 transcriptional regulator 2154909 8163682 TBMG_01962 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031925.1 2154604 D 478434 CDS YP_003031926.1 253798925 8163683 2154994..2155293 1 NC_012943.1 hypothetical protein 2155293 8163683 TBMG_01963 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031926.1 2154994 D 478434 CDS YP_003031927.1 253798926 8163684 complement(2155309..2155611) 1 NC_012943.1 hypothetical protein 2155611 8163684 TBMG_01964 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031927.1 2155309 R 478434 CDS YP_003031928.1 253798927 8163685 complement(2155671..2156555) 1 NC_012943.1 transposase 2156555 8163685 TBMG_01965 Mycobacterium tuberculosis KZN 1435 transposase YP_003031928.1 2155671 R 478434 CDS YP_003031929.1 253798928 8163686 complement(2156606..2156932) 1 NC_012943.1 transposase 2156932 8163686 TBMG_01966 Mycobacterium tuberculosis KZN 1435 transposase YP_003031929.1 2156606 R 478434 CDS YP_003031930.1 253798929 8163687 complement(2157073..2157801) 1 NC_012943.1 hypothetical protein 2157801 8163687 TBMG_01967 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031930.1 2157073 R 478434 CDS YP_003031931.1 253798930 8163688 complement(2158034..2159074) 1 NC_012943.1 transcriptional regulator 2159074 8163688 TBMG_01968 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031931.1 2158034 R 478434 CDS YP_003031932.1 253798931 8163689 complement(2159071..2159682) 1 NC_012943.1 hypothetical protein 2159682 8163689 TBMG_01969 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031932.1 2159071 R 478434 CDS YP_003031933.1 253798932 8163690 2160000..2161256 1 NC_012943.1 hypothetical protein 2161256 8163690 TBMG_01970 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031933.1 2160000 D 478434 CDS YP_003031934.1 253798933 8163691 complement(2161384..2161974) 1 NC_012943.1 transposase 2161974 8163691 TBMG_01971 Mycobacterium tuberculosis KZN 1435 transposase YP_003031934.1 2161384 R 478434 CDS YP_003031935.1 253798934 8163692 complement(2161928..2162548) 1 NC_012943.1 transposase 2162548 8163692 TBMG_01972 Mycobacterium tuberculosis KZN 1435 transposase YP_003031935.1 2161928 R 478434 CDS YP_003031936.1 253798935 8163693 complement(2163007..2163255) 1 NC_012943.1 hypothetical protein 2163255 8163693 TBMG_01973 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031936.1 2163007 R 478434 CDS YP_003031937.1 253798936 8163694 complement(2163252..2163746) 1 NC_012943.1 hypothetical protein 2163746 8163694 TBMG_01974 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031937.1 2163252 R 478434 CDS YP_003031938.1 253798937 8163695 2163787..2164218 1 NC_012943.1 hypothetical protein 2164218 8163695 TBMG_01975 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031938.1 2163787 D 478434 CDS YP_003031939.1 253798938 8163696 complement(2164401..2164799) 1 NC_012943.1 toxin 2164799 8163696 TBMG_01976 Mycobacterium tuberculosis KZN 1435 toxin YP_003031939.1 2164401 R 478434 CDS YP_003031940.1 253798939 8163697 complement(2164800..2165042) 1 NC_012943.1 antitoxin 2165042 8163697 TBMG_01977 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031940.1 2164800 R 478434 CDS YP_003031941.1 253798940 8163698 2165130..2166455 1 NC_012943.1 hypothetical protein 2166455 8163698 TBMG_01978 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031941.1 2165130 D 478434 CDS YP_003031942.1 253798941 8163699 2166644..2166988 1 NC_012943.1 ferredoxin fdxA 2166988 8163699 TBMG_01979 Mycobacterium tuberculosis KZN 1435 ferredoxin fdxA YP_003031942.1 2166644 D 478434 CDS YP_003031943.1 253798942 8163700 complement(2167087..2171070) 1 NC_012943.1 trehalose-6-phosphate phosphatase otsB1 2171070 8163700 TBMG_01980 Mycobacterium tuberculosis KZN 1435 trehalose-6-phosphate phosphatase otsB1 YP_003031943.1 2167087 R 478434 CDS YP_003031944.1 253798943 8163701 2171189..2172076 1 NC_012943.1 hypothetical protein 2172076 8163701 TBMG_01981 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031944.1 2171189 D 478434 CDS YP_003031945.1 253798944 8163702 2172098..2173594 1 NC_012943.1 hypothetical protein 2173594 8163702 TBMG_01982 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031945.1 2172098 D 478434 CDS YP_003031946.1 253798945 8163703 2173652..2174509 1 NC_012943.1 hypothetical protein 2174509 8163703 TBMG_01983 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031946.1 2173652 D 478434 CDS YP_003031947.1 253798946 8163704 complement(2174630..2175412) 1 NC_012943.1 20-beta-hydroxysteroid dehydrogenase 2175412 8163704 TBMG_01984 Mycobacterium tuberculosis KZN 1435 20-beta-hydroxysteroid dehydrogenase YP_003031947.1 2174630 R 478434 CDS YP_003031948.1 253798947 8163705 complement(2175488..2176240) 1 NC_012943.1 hypothetical protein 2176240 8163705 TBMG_01985 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031948.1 2175488 R 478434 CDS YP_003031949.1 253798948 8161238 complement(2176250..2177863) 1 NC_012943.1 hypothetical protein 2177863 8161238 TBMG_01986 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031949.1 2176250 R 478434 CDS YP_003031950.1 253798949 8161239 2177934..2179256 1 NC_012943.1 hypothetical protein 2179256 8161239 TBMG_01987 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031950.1 2177934 D 478434 CDS YP_003031951.1 253798950 8161240 2179351..2180127 1 NC_012943.1 hypothetical protein 2180127 8161240 TBMG_01988 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031951.1 2179351 D 478434 CDS YP_003031952.1 253798951 8161241 complement(2180196..2182913) 1 NC_012943.1 metal cation transporting P-type ATPase ctpF 2182913 8161241 TBMG_01989 Mycobacterium tuberculosis KZN 1435 metal cation transporting P-type ATPase ctpF YP_003031952.1 2180196 R 478434 CDS YP_003031953.1 253798952 8161242 complement(2183115..2184068) 1 NC_012943.1 hypothetical protein 2184068 8161242 TBMG_01990 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031953.1 2183115 R 478434 CDS YP_003031954.1 253798953 8161243 complement(2184164..2184931) 1 NC_012943.1 hypothetical protein 2184931 8161243 TBMG_01991 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031954.1 2184164 R 478434 CDS YP_003031955.1 253798954 8161244 2185088..2185444 1 NC_012943.1 transcriptional regulator 2185444 8161244 TBMG_01992 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031955.1 2185088 D 478434 CDS YP_003031956.1 253798955 8161245 2185497..2185769 1 NC_012943.1 hypothetical protein 2185769 8161245 TBMG_01993 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031956.1 2185497 D 478434 CDS YP_003031957.1 253798956 8161246 2185766..2188081 1 NC_012943.1 metal cation transporting P-type ATPase ctpG 2188081 8161246 TBMG_01994 Mycobacterium tuberculosis KZN 1435 metal cation transporting P-type ATPase ctpG YP_003031957.1 2185766 D 478434 CDS YP_003031958.1 253798957 8161247 2188181..2188429 1 NC_012943.1 antitoxin 2188429 8161247 TBMG_01995 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031958.1 2188181 D 478434 CDS YP_003031959.1 253798958 8161248 2188423..2188767 1 NC_012943.1 toxin 2188767 8161248 TBMG_01996 Mycobacterium tuberculosis KZN 1435 toxin YP_003031959.1 2188423 D 478434 CDS YP_003031960.1 253798959 8161249 2188856..2189191 1 NC_012943.1 dehydrogenase 2189191 8161249 TBMG_01997 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003031960.1 2188856 D 478434 CDS YP_003031961.1 253798960 8161250 2189435..2189776 1 NC_012943.1 transcriptional regulator 2189776 8161250 TBMG_01998 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003031961.1 2189435 D 478434 CDS YP_003031962.1 253798961 8161251 2189773..2190333 1 NC_012943.1 hypothetical protein 2190333 8161251 TBMG_01999 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031962.1 2189773 D 478434 CDS YP_003031963.1 253798962 8161252 complement(2190853..2191392) 1 NC_012943.1 methyltransferase 2191392 8161252 TBMG_02000 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003031963.1 2190853 R 478434 CDS YP_003031964.1 253798963 8161253 complement(2191618..2192046) 1 NC_012943.1 chitinase 2192046 8161253 TBMG_02001 Mycobacterium tuberculosis KZN 1435 chitinase YP_003031964.1 2191618 R 478434 CDS YP_003031965.1 253798964 8161254 complement(2192462..2193061) 1 NC_012943.1 hypothetical protein 2193061 8161254 TBMG_02002 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031965.1 2192462 R 478434 CDS YP_003031966.1 253798965 8161255 2193170..2194081 1 NC_012943.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 2194081 8161255 TBMG_02003 Mycobacterium tuberculosis KZN 1435 chromosome replication initiation inhibitor protein YP_003031966.1 2193170 D 478434 CDS YP_003031967.1 253798966 8161256 complement(2194166..2194396) 1 NC_012943.1 PE-PGRS family protein 2194396 8161256 TBMG_02004 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031967.1 2194166 R 478434 CDS YP_003031968.1 253798967 8161257 2194511..2195164 1 NC_012943.1 cutinase precursor cfp21 2195164 8161257 TBMG_02005 Mycobacterium tuberculosis KZN 1435 cutinase precursor cfp21 YP_003031968.1 2194511 D 478434 CDS YP_003031969.1 253798968 8161258 complement(2195152..2196828) 1 NC_012943.1 PE-PGRS family protein 2196828 8161258 TBMG_02006 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003031969.1 2195152 R 478434 CDS YP_003031970.1 253798969 8161259 2196971..2197231 1 NC_012943.1 antitoxin 2197231 8161259 TBMG_02007 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031970.1 2196971 D 478434 CDS YP_003031971.1 253798970 8161260 2197240..2197659 1 NC_012943.1 toxin 2197659 8161260 TBMG_02008 Mycobacterium tuberculosis KZN 1435 toxin YP_003031971.1 2197240 D 478434 CDS YP_003031972.1 253798971 8161261 2197884..2198852 1 NC_012943.1 ribonucleotide-diphosphate reductase subunit beta 2198852 nrdF1 8161261 nrdF1 Mycobacterium tuberculosis KZN 1435 ribonucleotide-diphosphate reductase subunit beta YP_003031972.1 2197884 D 478434 CDS YP_003031973.1 253798972 8161262 2199043..2199729 1 NC_012943.1 hypothetical protein 2199729 8161262 TBMG_02010 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031973.1 2199043 D 478434 CDS YP_003031974.1 253798973 8161263 2199908..2201353 1 NC_012943.1 permease 2201353 8161263 TBMG_02011 Mycobacterium tuberculosis KZN 1435 permease YP_003031974.1 2199908 D 478434 CDS YP_003031975.1 253798974 8161264 complement(2201316..2202164) 1 NC_012943.1 hypothetical protein 2202164 8161264 TBMG_02012 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031975.1 2201316 R 478434 CDS YP_003031976.1 253798975 8161265 complement(2202272..2203318) 1 NC_012943.1 hypothetical protein 2203318 8161265 TBMG_02013 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031976.1 2202272 R 478434 CDS YP_003031977.1 253798976 8161266 2203821..2204228 1 NC_012943.1 hypothetical protein 2204228 8161266 TBMG_02014 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031977.1 2203821 D 478434 CDS YP_003031978.1 253798977 8161267 complement(2204355..2204963) 1 NC_012943.1 hypothetical protein 2204963 8161267 TBMG_02015 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031978.1 2204355 R 478434 CDS YP_003031979.1 253798978 8161268 complement(2205036..2205413) 1 NC_012943.1 hypothetical protein 2205413 8161268 TBMG_02016 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031979.1 2205036 R 478434 CDS YP_003031980.1 253798979 8161269 complement(2205426..2205908) 1 NC_012943.1 hypothetical protein 2205908 8161269 TBMG_02017 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031980.1 2205426 R 478434 CDS YP_003031981.1 253798980 8161270 complement(2205905..2206480) 1 NC_012943.1 hypothetical protein 2206480 8161270 TBMG_02018 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031981.1 2205905 R 478434 CDS YP_003031982.1 253798981 8161271 complement(2206502..2207815) 1 NC_012943.1 MCE-family protein mce3F 2207815 8161271 TBMG_02019 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce3F YP_003031982.1 2206502 R 478434 CDS YP_003031983.1 253798982 8161272 complement(2207816..2208949) 1 NC_012943.1 MCE-family lipoprotein mce3E 2208949 8161272 TBMG_02020 Mycobacterium tuberculosis KZN 1435 MCE-family lipoprotein mce3E YP_003031983.1 2207816 R 478434 CDS YP_003031984.1 253798983 8161273 complement(2208946..2210187) 1 NC_012943.1 MCE-family protein mce3D 2210187 8161273 TBMG_02021 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce3D YP_003031984.1 2208946 R 478434 CDS YP_003031985.1 253798984 8161274 complement(2210214..2211458) 1 NC_012943.1 MCE-family protein mce3C 2211458 8161274 TBMG_02022 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce3C YP_003031985.1 2210214 R 478434 CDS YP_003031986.1 253798985 8161275 complement(2211443..2212471) 1 NC_012943.1 MCE-family protein mce3B 2212471 8161275 TBMG_02023 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce3B YP_003031986.1 2211443 R 478434 CDS YP_003031987.1 253798986 8161276 complement(2212468..2213745) 1 NC_012943.1 MCE-family protein mce3A 2213745 8161276 TBMG_02024 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce3A YP_003031987.1 2212468 R 478434 CDS YP_003031988.1 253798987 8161277 complement(2213750..2214565) 1 NC_012943.1 hypothetical protein 2214565 8161277 TBMG_02025 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031988.1 2213750 R 478434 CDS YP_003031989.1 253798988 8161278 complement(2214575..2215384) 1 NC_012943.1 hypothetical protein 2215384 8161278 TBMG_02026 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031989.1 2214575 R 478434 CDS YP_003031990.1 253798989 8161279 2215600..2216052 1 NC_012943.1 hypothetical protein 2216052 8161279 TBMG_02027 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031990.1 2215600 D 478434 CDS YP_003031991.1 253798990 8161280 2216271..2217491 1 NC_012943.1 TetR family transcriptional regulator 2217491 8161280 TBMG_02028 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003031991.1 2216271 D 478434 CDS YP_003031992.1 253798991 8161281 2217524..2217796 1 NC_012943.1 antitoxin 2217796 8161281 TBMG_02029 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031992.1 2217524 D 478434 CDS YP_003031993.1 253798992 8161282 2217800..2218207 1 NC_012943.1 toxin 2218207 8161282 TBMG_02030 Mycobacterium tuberculosis KZN 1435 toxin YP_003031993.1 2217800 D 478434 CDS YP_003031994.1 253798993 8161283 complement(2218367..2218861) 1 NC_012943.1 hypothetical protein 2218861 8161283 TBMG_02031 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031994.1 2218367 R 478434 CDS YP_003031995.1 253798994 8161285 2218848..2219099 1 NC_012943.1 antitoxin 2219099 8161285 TBMG_02032 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003031995.1 2218848 D 478434 CDS YP_003031996.1 253798995 8161284 2219096..2219392 1 NC_012943.1 toxin 2219392 8161284 TBMG_02033 Mycobacterium tuberculosis KZN 1435 toxin YP_003031996.1 2219096 D 478434 CDS YP_003031997.1 253798996 8161286 2219441..2220055 1 NC_012943.1 hypothetical protein 2220055 8161286 TBMG_02034 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031997.1 2219441 D 478434 CDS YP_003031998.1 253798997 8161287 complement(2219944..2220489) 1 NC_012943.1 hypothetical protein 2220489 8161287 TBMG_02035 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003031998.1 2219944 R 478434 CDS YP_003031999.1 253798998 8161288 complement(2220486..2220935) 1 NC_012943.1 antitoxin, transcriptional regulator 2220935 8161288 TBMG_02036 Mycobacterium tuberculosis KZN 1435 antitoxin, transcriptional regulator YP_003031999.1 2220486 R 478434 CDS YP_003032000.1 253798999 8161289 complement(2220977..2221330) 1 NC_012943.1 toxin 2221330 8161289 TBMG_02037 Mycobacterium tuberculosis KZN 1435 toxin YP_003032000.1 2220977 R 478434 CDS YP_003032001.1 253799000 8161290 complement(2221824..2222135) 1 NC_012943.1 toxin 2222135 8161290 TBMG_02039 Mycobacterium tuberculosis KZN 1435 toxin YP_003032001.1 2221824 R 478434 CDS YP_003032002.1 253799001 8161291 complement(2222132..2222347) 1 NC_012943.1 antitoxin 2222347 8161291 TBMG_02040 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032002.1 2222132 R 478434 CDS YP_003032003.1 253799002 8161292 2222587..2222883 1 NC_012943.1 hypothetical protein 2222883 8161292 TBMG_02041 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032003.1 2222587 D 478434 CDS YP_003032004.1 253799003 8161293 2222884..2223075 1 NC_012943.1 hypothetical protein 2223075 8161293 TBMG_02042 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032004.1 2222884 D 478434 CDS YP_003032005.1 253799004 8161294 2223096..2223998 1 NC_012943.1 hypothetical protein 2223998 8161294 TBMG_02043 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032005.1 2223096 D 478434 CDS YP_003032006.1 253799005 8161295 2224009..2224359 1 NC_012943.1 hypothetical protein 2224359 8161295 TBMG_02044 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032006.1 2224009 D 478434 CDS YP_003032007.1 253799006 8161296 complement(2224648..2225049) 1 NC_012943.1 hypothetical protein 2225049 8161296 TBMG_02045 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032007.1 2224648 R 478434 CDS YP_003032008.1 253799007 8161297 2225113..2225565 1 NC_012943.1 hypothetical protein 2225565 8161297 TBMG_02046 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032008.1 2225113 D 478434 CDS YP_003032009.1 253799008 8161298 complement(2225720..2227168) 1 NC_012943.1 hypothetical protein 2227168 8161298 TBMG_02047 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032009.1 2225720 R 478434 CDS YP_003032010.1 253799009 8161300 2227139..2227729 1 NC_012943.1 hypothetical protein 2227729 8161300 TBMG_02048 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032010.1 2227139 D 478434 CDS YP_003032011.1 253799010 8161299 2227726..2228103 1 NC_012943.1 antitoxin 2228103 8161299 TBMG_02049 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032011.1 2227726 D 478434 CDS YP_003032012.1 253799011 8161301 2228100..2228429 1 NC_012943.1 toxin 2228429 8161301 TBMG_02050 Mycobacterium tuberculosis KZN 1435 toxin YP_003032012.1 2228100 D 478434 CDS YP_003032013.1 253799012 8161302 complement(2228639..2229409) 1 NC_012943.1 short-chain type dehydrogenase/reductase 2229409 8161302 TBMG_02051 Mycobacterium tuberculosis KZN 1435 short-chain type dehydrogenase/reductase YP_003032013.1 2228639 R 478434 CDS YP_003032014.1 253799013 8161303 complement(2229406..2230467) 1 NC_012943.1 riboflavin biosynthesis protein ribA1 2230467 8161303 TBMG_02052 Mycobacterium tuberculosis KZN 1435 riboflavin biosynthesis protein ribA1 YP_003032014.1 2229406 R 478434 CDS YP_003032015.1 253799014 8161304 complement(2230464..2230979) 1 NC_012943.1 oxidoreductase 2230979 8161304 TBMG_02053 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032015.1 2230464 R 478434 CDS YP_003032016.1 253799015 8161305 complement(2230976..2232046) 1 NC_012943.1 epoxide hydrolase ephB 2232046 8161305 TBMG_02054 Mycobacterium tuberculosis KZN 1435 epoxide hydrolase ephB YP_003032016.1 2230976 R 478434 CDS YP_003032017.1 253799016 8161306 complement(2232058..2234577) 1 NC_012943.1 oxygenase 2234577 8161306 TBMG_02055 Mycobacterium tuberculosis KZN 1435 oxygenase YP_003032017.1 2232058 R 478434 CDS YP_003032018.1 253799017 8161307 complement(2234580..2235689) 1 NC_012943.1 monooxygenase 2235689 8161307 TBMG_02056 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003032018.1 2234580 R 478434 CDS YP_003032019.1 253799018 8161308 2235914..2236870 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2236870 8161308 TBMG_02057 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003032019.1 2235914 D 478434 CDS YP_003032020.1 253799019 8161309 2236885..2238114 1 NC_012943.1 acyl-CoA dehydrogenase 2238114 8161309 TBMG_02058 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003032020.1 2236885 D 478434 CDS YP_003032021.1 253799020 8161310 2238116..2239207 1 NC_012943.1 acyl-CoA dehydrogenase 2239207 8161310 TBMG_02059 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003032021.1 2238116 D 478434 CDS YP_003032022.1 253799021 8161311 complement(2239204..2239701) 1 NC_012943.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 2239701 tpx 8161311 tpx Mycobacterium tuberculosis KZN 1435 thiol peroxidase YP_003032022.1 2239204 R 478434 CDS YP_003032023.1 253799022 8161312 2239822..2240613 1 NC_012943.1 transcriptional regulator 2240613 8161312 TBMG_02061 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032023.1 2239822 D 478434 CDS YP_003032024.1 253799023 8161313 2240631..2241155 1 NC_012943.1 hypothetical protein 2241155 8161313 TBMG_02062 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032024.1 2240631 D 478434 CDS YP_003032025.1 253799024 8161314 2241167..2241811 1 NC_012943.1 hypothetical protein 2241811 8161314 TBMG_02063 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032025.1 2241167 D 478434 CDS YP_003032026.1 253799025 8161315 2241856..2242623 1 NC_012943.1 short chain dehydrogenase 2242623 8161315 TBMG_02064 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003032026.1 2241856 D 478434 CDS YP_003032027.1 253799026 8161316 complement(2242627..2243400) 1 NC_012943.1 hypothetical protein 2243400 8161316 TBMG_02065 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032027.1 2242627 R 478434 CDS YP_003032028.1 253799027 8161317 2243637..2244116 1 NC_012943.1 hypothetical protein 2244116 8161317 TBMG_02066 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032028.1 2243637 D 478434 CDS YP_003032029.1 253799028 8163064 complement(2244124..2245986) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; fatty-acid--CoA ligase 2245986 8163064 TBMG_02067 Mycobacterium tuberculosis KZN 1435 fatty-acid--CoA ligase YP_003032029.1 2244124 R 478434 CDS YP_003032030.1 253799029 8163065 2246143..2246523 1 NC_012943.1 hypothetical protein 2246523 8163065 TBMG_02068 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032030.1 2246143 D 478434 CDS YP_003032031.1 253799030 8163066 complement(2246560..2247900) 1 NC_012943.1 lipase lipD 2247900 8163066 TBMG_02069 Mycobacterium tuberculosis KZN 1435 lipase lipD YP_003032031.1 2246560 R 478434 CDS YP_003032032.1 253799031 8163067 complement(2247891..2249006) 1 NC_012943.1 lipoprotein 2249006 8163067 TBMG_02070 Mycobacterium tuberculosis KZN 1435 lipoprotein YP_003032032.1 2247891 R 478434 CDS YP_003032033.1 253799032 8163068 2249278..2250549 1 NC_012943.1 hypothetical protein 2250549 8163068 TBMG_02071 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032033.1 2249278 D 478434 CDS YP_003032034.1 253799033 8163069 complement(2250587..2251450) 1 NC_012943.1 hypothetical protein 2251450 8163069 TBMG_02072 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032034.1 2250587 R 478434 CDS YP_003032035.1 253799034 8163070 2251548..2252012 1 NC_012943.1 hypothetical protein 2252012 8163070 TBMG_02073 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032035.1 2251548 D 478434 CDS YP_003032036.1 253799035 8163071 2252461..2255424 1 NC_012943.1 PPE family protein 2255424 8163071 TBMG_02074 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032036.1 2252461 D 478434 CDS YP_003032037.1 253799036 8163072 2255729..2259928 1 NC_012943.1 PPE family protein 2259928 8163072 TBMG_02075 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032037.1 2255729 D 478434 CDS YP_003032038.1 253799037 8163073 complement(2260098..2261294) 1 NC_012943.1 isocitrate lyase aceAb 2261294 8163073 TBMG_02076 Mycobacterium tuberculosis KZN 1435 isocitrate lyase aceAb YP_003032038.1 2260098 R 478434 CDS YP_003032039.1 253799038 8163074 complement(2261294..2262397) 1 NC_012943.1 isocitrate lyase aceAa 2262397 8163074 TBMG_02077 Mycobacterium tuberculosis KZN 1435 isocitrate lyase aceAa YP_003032039.1 2261294 R 478434 CDS YP_003032040.1 253799039 8163075 2262532..2262939 1 NC_012943.1 hypothetical protein 2262939 8163075 TBMG_02078 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032040.1 2262532 D 478434 CDS YP_003032041.1 253799040 8163076 complement(2262917..2263669) 1 NC_012943.1 hypothetical protein 2263669 8163076 TBMG_02079 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032041.1 2262917 R 478434 CDS YP_003032042.1 253799041 8163077 2263769..2264773 1 NC_012943.1 oxidoreductase fadB5 2264773 8163077 TBMG_02080 Mycobacterium tuberculosis KZN 1435 oxidoreductase fadB5 YP_003032042.1 2263769 D 478434 CDS YP_003032043.1 253799042 8163078 2264861..2265478 1 NC_012943.1 hypothetical protein 2265478 8163078 TBMG_02081 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032043.1 2264861 D 478434 CDS YP_003032044.1 253799043 8163079 2265540..2266154 1 NC_012943.1 hypothetical protein 2266154 8163079 TBMG_02082 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032044.1 2265540 D 478434 CDS YP_003032045.1 253799044 8163080 2266259..2266711 1 NC_012943.1 ferric uptake regulation protein furA 2266711 8163080 TBMG_02083 Mycobacterium tuberculosis KZN 1435 ferric uptake regulation protein furA YP_003032045.1 2266259 D 478434 CDS YP_003032046.1 253799045 8163081 2266749..2268971 1 NC_012943.1 catalase-peroxidase-peroxynitritase T katG 2268971 8163081 TBMG_02084 Mycobacterium tuberculosis KZN 1435 catalase-peroxidase-peroxynitritase T katG YP_003032046.1 2266749 D 478434 CDS YP_003032047.1 253799046 8163082 2268978..2269625 1 NC_012943.1 hypothetical protein 2269625 8163082 TBMG_02085 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032047.1 2268978 D 478434 CDS YP_003032048.1 253799047 8163083 2269677..2269907 1 NC_012943.1 hypothetical protein 2269907 8163083 TBMG_04048 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032048.1 2269677 D 478434 CDS YP_003032049.1 253799048 8163084 2269965..2270435 1 NC_012943.1 hypothetical protein 2270435 8163084 TBMG_02086 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032049.1 2269965 D 478434 CDS YP_003032050.1 253799049 8163085 2270465..2271427 1 NC_012943.1 D-amino acid oxidase aao 2271427 8163085 TBMG_02087 Mycobacterium tuberculosis KZN 1435 D-amino acid oxidase aao YP_003032050.1 2270465 D 478434 CDS YP_003032051.1 253799050 8163086 complement(2271475..2271906) 1 NC_012943.1 hypothetical protein 2271906 8163086 TBMG_02088 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032051.1 2271475 R 478434 CDS YP_003032052.1 253799051 8163087 complement(2272092..2272496) 1 NC_012943.1 hypothetical protein 2272496 8163087 TBMG_02089 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032052.1 2272092 R 478434 CDS YP_003032053.1 253799052 8163088 2272586..2273854 1 NC_012943.1 hypothetical protein 2273854 8163088 TBMG_02090 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032053.1 2272586 D 478434 CDS YP_003032054.1 253799053 8163089 complement(2273906..2275198) 1 NC_012943.1 competence damage-inducible protein A 2275198 8163089 TBMG_02091 Mycobacterium tuberculosis KZN 1435 competence damage-inducible protein A YP_003032054.1 2273906 R 478434 CDS YP_003032055.1 253799054 8163090 2275227..2276615 1 NC_012943.1 lignin peroxidase lipJ 2276615 8163090 TBMG_04049 Mycobacterium tuberculosis KZN 1435 lignin peroxidase lipJ YP_003032055.1 2275227 D 478434 CDS YP_003032056.1 253799055 8163091 2276567..2277691 1 NC_012943.1 hypothetical protein 2277691 8163091 TBMG_04050 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032056.1 2276567 D 478434 CDS YP_003032057.1 253799056 8163092 complement(2277657..2277965) 1 NC_012943.1 hypothetical protein 2277965 8163092 TBMG_02094 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032057.1 2277657 R 478434 CDS YP_003032058.1 253799057 8163093 2278023..2278454 1 NC_012943.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2278454 8163093 TBMG_02095 Mycobacterium tuberculosis KZN 1435 D-tyrosyl-tRNA(Tyr) deacylase YP_003032058.1 2278023 D 478434 CDS YP_003032059.1 253799058 8163094 2278459..2279370 1 NC_012943.1 hypothetical protein 2279370 8163094 TBMG_02096 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032059.1 2278459 D 478434 CDS YP_003032060.1 253799059 8163095 complement(2279230..2280384) 1 NC_012943.1 dehydrogenase 2280384 8163095 TBMG_02097 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003032060.1 2279230 R 478434 CDS YP_003032061.1 253799060 8163096 complement(2280532..2280963) 1 NC_012943.1 hypothetical protein 2280963 8163096 TBMG_02098 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032061.1 2280532 R 478434 CDS YP_003032062.1 253799061 8163097 2281036..2282166 1 NC_012943.1 hypothetical protein 2282166 8163097 TBMG_02099 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032062.1 2281036 D 478434 CDS YP_003032063.1 253799062 8163098 complement(2282201..2282419) 1 NC_012943.1 hypothetical protein 2282419 8163098 TBMG_02100 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032063.1 2282201 R 478434 CDS YP_003032064.1 253799063 8163099 complement(2282429..2282740) 1 NC_012943.1 hypothetical protein 2282740 8163099 TBMG_02101 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032064.1 2282429 R 478434 CDS YP_003032065.1 253799064 8163100 complement(2282757..2283164) 1 NC_012943.1 hypothetical protein 2283164 8163100 TBMG_02102 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032065.1 2282757 R 478434 CDS YP_003032066.1 253799065 8163101 2283218..2283829 1 NC_012943.1 hypothetical protein 2283829 8163101 TBMG_02103 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032066.1 2283218 D 478434 CDS YP_003032067.1 253799066 8163102 2283888..2284244 1 NC_012943.1 methyltransferase 2284244 8163102 TBMG_02104 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032067.1 2283888 D 478434 CDS YP_003032068.1 253799067 8163103 2284288..2284461 1 NC_012943.1 hypothetical protein 2284461 8163103 TBMG_02105 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032068.1 2284288 D 478434 CDS YP_003032069.1 253799068 8163104 2284787..2285545 1 NC_012943.1 hypothetical protein 2285545 8163104 TBMG_02106 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032069.1 2284787 D 478434 CDS YP_003032070.1 253799069 8163105 complement(2285515..2286657) 1 NC_012943.1 hypothetical protein 2286657 8163105 TBMG_02107 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032070.1 2285515 R 478434 CDS YP_003032071.1 253799070 8163106 2287048..2288025 1 NC_012943.1 secreted fibronectin-binding protein antigen 85-B fbpB 2288025 8163106 TBMG_02108 Mycobacterium tuberculosis KZN 1435 secreted fibronectin-binding protein antigen 85-B fbpB YP_003032071.1 2287048 D 478434 CDS YP_003032072.1 253799071 8163107 2288043..2288642 1 NC_012943.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 2288642 8163107 TBMG_02109 Mycobacterium tuberculosis KZN 1435 chorismate mutase YP_003032072.1 2288043 D 478434 CDS YP_003032073.1 253799072 8163108 2288654..2289184 1 NC_012943.1 resuscitation-promoting factor rpfC 2289184 8163108 TBMG_02110 Mycobacterium tuberculosis KZN 1435 resuscitation-promoting factor rpfC YP_003032073.1 2288654 D 478434 CDS YP_003032074.1 253799073 8163109 2289223..2289699 1 NC_012943.1 hypothetical protein 2289699 8163109 TBMG_02111 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032074.1 2289223 D 478434 CDS YP_003032075.1 253799074 8163110 2289727..2290560 1 NC_012943.1 short chain dehydrogenase 2290560 8163110 TBMG_02112 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003032075.1 2289727 D 478434 CDS YP_003032076.1 253799075 8163111 2290601..2291023 1 NC_012943.1 hypothetical protein 2291023 8163111 TBMG_02113 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032076.1 2290601 D 478434 CDS YP_003032077.1 253799076 8163112 2291073..2292389 1 NC_012943.1 cytochrome P450 140 cyp140 2292389 8163112 TBMG_02114 Mycobacterium tuberculosis KZN 1435 cytochrome P450 140 cyp140 YP_003032077.1 2291073 D 478434 CDS YP_003032078.1 253799077 8163113 complement(2292417..2293553) 1 NC_012943.1 hypothetical protein 2293553 8163113 TBMG_02115 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032078.1 2292417 R 478434 CDS YP_003032079.1 253799078 8163114 complement(2293556..2294908) 1 NC_012943.1 glutamine synthetase glnA3 2294908 8163114 TBMG_02116 Mycobacterium tuberculosis KZN 1435 glutamine synthetase glnA3 YP_003032079.1 2293556 R 478434 CDS YP_003032080.1 253799079 8163115 complement(2294963..2297026) 1 NC_012943.1 hypothetical protein 2297026 8163115 TBMG_02117 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032080.1 2294963 R 478434 CDS YP_003032081.1 253799080 8163116 complement(2297111..2297590) 1 NC_012943.1 bacterioferritin bfrA 2297590 8163116 TBMG_02118 Mycobacterium tuberculosis KZN 1435 bacterioferritin bfrA YP_003032081.1 2297111 R 478434 CDS YP_003032082.1 253799081 8163117 complement(2298106..2298549) 1 NC_012943.1 hypothetical protein 2298549 8163117 TBMG_02119 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032082.1 2298106 R 478434 CDS YP_003032083.1 253799082 8163118 complement(2298560..2299264) 1 NC_012943.1 hypothetical protein 2299264 8163118 TBMG_02120 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032083.1 2298560 R 478434 CDS YP_003032084.1 253799083 8163119 complement(2299319..2299756) 1 NC_012943.1 hypothetical protein 2299756 8163119 TBMG_02121 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032084.1 2299319 R 478434 CDS YP_003032085.1 253799084 8163120 2299779..2301023 1 NC_012943.1 L-lactate dehydrogenase lldD2 2301023 8163120 TBMG_02122 Mycobacterium tuberculosis KZN 1435 L-lactate dehydrogenase lldD2 YP_003032085.1 2299779 D 478434 CDS YP_003032086.1 253799085 8163121 2301046..2301435 1 NC_012943.1 hypothetical protein 2301435 8163121 TBMG_02123 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032086.1 2301046 D 478434 CDS YP_003032087.1 253799086 8163122 2301500..2302135 1 NC_012943.1 hypothetical protein 2302135 8163122 TBMG_02124 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032087.1 2301500 D 478434 CDS YP_003032088.1 253799087 8163123 2302235..2303470 1 NC_012943.1 reductase 2303470 8163123 TBMG_02125 Mycobacterium tuberculosis KZN 1435 reductase YP_003032088.1 2302235 D 478434 CDS YP_003032089.1 253799088 8163124 complement(2303484..2305583) 1 NC_012943.1 hypothetical protein 2305583 8163124 TBMG_02126 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032089.1 2303484 R 478434 CDS YP_003032090.1 253799089 8163125 complement(2305682..2307166) 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 2307166 8163125 TBMG_02127 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003032090.1 2305682 R 478434 CDS YP_003032091.1 253799090 8163126 complement(2307454..2309862) 1 NC_012943.1 hypothetical protein 2309862 8163126 TBMG_02128 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032091.1 2307454 R 478434 CDS YP_003032092.1 253799091 8163127 2309964..2310824 1 NC_012943.1 short chain dehydrogenase 2310824 8163127 TBMG_02129 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003032092.1 2309964 D 478434 CDS YP_003032093.1 253799092 8163128 2310821..2311576 1 NC_012943.1 hypothetical protein 2311576 8163128 TBMG_02130 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032093.1 2310821 D 478434 CDS YP_003032094.1 253799093 8163129 2311569..2312339 1 NC_012943.1 hypothetical protein 2312339 8163129 TBMG_02131 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032094.1 2311569 D 478434 CDS YP_003032095.1 253799094 8163130 complement(2312346..2313386) 1 NC_012943.1 alcohol dehydrogenase 2313386 8163130 TBMG_02132 Mycobacterium tuberculosis KZN 1435 alcohol dehydrogenase YP_003032095.1 2312346 R 478434 CDS YP_003032096.1 253799095 8163131 complement(2313461..2313766) 1 NC_012943.1 hypothetical protein 2313766 8163131 TBMG_02133 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032096.1 2313461 R 478434 CDS YP_003032097.1 253799096 8163132 complement(2314218..2315195) 1 NC_012943.1 hypothetical protein 2315195 8163132 TBMG_02134 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032097.1 2314218 R 478434 CDS YP_003032098.1 253799097 8163133 complement(2315248..2316357) 1 NC_012943.1 molybdenum-transport ATP-binding protein ABC transporter modC 2316357 8163133 TBMG_02135 Mycobacterium tuberculosis KZN 1435 molybdenum-transport ATP-binding protein ABC transporter modC YP_003032098.1 2315248 R 478434 CDS YP_003032099.1 253799098 8163134 complement(2316364..2317158) 1 NC_012943.1 hypothetical protein 2317158 8163134 TBMG_02136 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032099.1 2316364 R 478434 CDS YP_003032100.1 253799099 8163135 complement(2317161..2317946) 1 NC_012943.1 molybdate-binding lipoprotein modA 2317946 8163135 TBMG_02137 Mycobacterium tuberculosis KZN 1435 molybdate-binding lipoprotein modA YP_003032100.1 2317161 R 478434 CDS YP_003032101.1 253799100 8163136 2318108..2318785 1 NC_012943.1 short chain dehydrogenase 2318785 8163136 TBMG_02138 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003032101.1 2318108 D 478434 CDS YP_003032102.1 253799101 8163137 2318824..2319747 1 NC_012943.1 oxidoreductase 2319747 8163137 TBMG_02139 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032102.1 2318824 D 478434 CDS YP_003032103.1 253799102 8163138 2319889..2321280 1 NC_012943.1 NADH dehydrogenase ndh 2321280 8163138 TBMG_02140 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase ndh YP_003032103.1 2319889 D 478434 CDS YP_003032104.1 253799103 8163139 complement(2321283..2321927) 1 NC_012943.1 urease accessory protein ureD 2321927 8163139 TBMG_02141 Mycobacterium tuberculosis KZN 1435 urease accessory protein ureD YP_003032104.1 2321283 R 478434 CDS YP_003032105.1 253799104 8163140 complement(2321917..2322591) 1 NC_012943.1 urease accessory protein ureG 2322591 8163140 TBMG_02142 Mycobacterium tuberculosis KZN 1435 urease accessory protein ureG YP_003032105.1 2321917 R 478434 CDS YP_003032106.1 253799105 8163141 complement(2322602..2323237) 1 NC_012943.1 urease accessory protein ureF 2323237 8163141 TBMG_02143 Mycobacterium tuberculosis KZN 1435 urease accessory protein ureF YP_003032106.1 2322602 R 478434 CDS YP_003032107.1 253799106 8163142 complement(2323237..2324970) 1 NC_012943.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 2324970 ureC 8163142 ureC Mycobacterium tuberculosis KZN 1435 urease subunit alpha YP_003032107.1 2323237 R 478434 CDS YP_003032108.1 253799107 8163461 complement(2324970..2325284) 1 NC_012943.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); urease subunit beta 2325284 ureB 8163461 ureB Mycobacterium tuberculosis KZN 1435 urease subunit beta YP_003032108.1 2324970 R 478434 CDS YP_003032109.1 253799108 8163462 complement(2325281..2325601) 1 NC_012943.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 2325601 ureA 8163462 ureA Mycobacterium tuberculosis KZN 1435 urease subunit gamma YP_003032109.1 2325281 R 478434 CDS YP_003032110.1 253799109 8163463 complement(2325632..2326054) 1 NC_012943.1 hypothetical protein 2326054 8163463 TBMG_02147 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032110.1 2325632 R 478434 CDS YP_003032111.1 253799110 8163464 2326332..2326748 1 NC_012943.1 transcriptional regulator 2326748 8163464 TBMG_02148 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032111.1 2326332 D 478434 CDS YP_003032112.1 253799111 8163465 2326763..2327713 1 NC_012943.1 hypothetical protein 2327713 8163465 TBMG_02149 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032112.1 2326763 D 478434 CDS YP_003032113.1 253799112 8163466 2327743..2329194 1 NC_012943.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2329194 8163466 TBMG_02150 Mycobacterium tuberculosis KZN 1435 6-phosphogluconate dehydrogenase YP_003032113.1 2327743 D 478434 CDS YP_003032114.1 253799113 8163467 2329227..2330666 1 NC_012943.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 2330666 8163467 TBMG_02151 Mycobacterium tuberculosis KZN 1435 inosine 5-monophosphate dehydrogenase YP_003032114.1 2329227 D 478434 CDS YP_003032115.1 253799114 8163468 2330840..2332207 1 NC_012943.1 hypothetical protein 2332207 8163468 TBMG_02152 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032115.1 2330840 D 478434 CDS YP_003032116.1 253799115 8163469 2332207..2333244 1 NC_012943.1 hypothetical protein 2333244 8163469 TBMG_02153 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032116.1 2332207 D 478434 CDS YP_003032117.1 253799116 8163470 2333407..2334954 1 NC_012943.1 PE-PGRS family protein 2334954 8163470 TBMG_02154 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032117.1 2333407 D 478434 CDS YP_003032118.1 253799117 8163471 2335013..2335276 1 NC_012943.1 antitoxin 2335276 8163471 TBMG_02155 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032118.1 2335013 D 478434 CDS YP_003032119.1 253799118 8163472 2335273..2335668 1 NC_012943.1 toxin 2335668 8163472 TBMG_02156 Mycobacterium tuberculosis KZN 1435 toxin YP_003032119.1 2335273 D 478434 CDS YP_003032120.1 253799119 8163473 2335962..2338169 1 NC_012943.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 2338169 8163473 TBMG_02157 Mycobacterium tuberculosis KZN 1435 malate synthase G YP_003032120.1 2335962 D 478434 CDS YP_003032121.1 253799120 8163474 complement(2338166..2338366) 1 NC_012943.1 hypothetical protein 2338366 8163474 TBMG_04051 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032121.1 2338166 R 478434 CDS YP_003032122.1 253799121 8163476 2338289..2340322 1 NC_012943.1 hypothetical protein 2340322 8163476 TBMG_02158 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032122.1 2338289 D 478434 CDS YP_003032123.1 253799122 8163475 2340338..2342224 1 NC_012943.1 hypothetical protein 2342224 8163475 TBMG_02159 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032123.1 2340338 D 478434 CDS YP_003032124.1 253799123 8163477 complement(2342229..2343095) 1 NC_012943.1 hydrolase 2343095 8163477 TBMG_02160 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003032124.1 2342229 R 478434 CDS YP_003032125.1 253799124 8163478 2343136..2343996 1 NC_012943.1 haloalkane dehalogenase 2343996 8163478 TBMG_02161 Mycobacterium tuberculosis KZN 1435 haloalkane dehalogenase YP_003032125.1 2343136 D 478434 CDS YP_003032126.1 253799125 8163479 complement(2344223..2347048) 1 NC_012943.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 2347048 8163479 TBMG_02162 Mycobacterium tuberculosis KZN 1435 glycine dehydrogenase YP_003032126.1 2344223 R 478434 CDS YP_003032127.1 253799126 8163480 complement(2347407..2348084) 1 NC_012943.1 hypothetical protein 2348084 8163480 TBMG_02163 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032127.1 2347407 R 478434 CDS YP_003032128.1 253799127 8163481 complement(2348432..2348926) 1 NC_012943.1 hypothetical protein 2348926 8163481 TBMG_02164 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032128.1 2348432 R 478434 CDS YP_003032129.1 253799128 8163482 complement(2349045..2349788) 1 NC_012943.1 hypothetical protein 2349788 8163482 TBMG_02165 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032129.1 2349045 R 478434 CDS YP_003032130.1 253799129 8163483 complement(2349785..2350273) 1 NC_012943.1 hypothetical protein 2350273 8163483 TBMG_02166 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032130.1 2349785 R 478434 CDS YP_003032131.1 253799130 8163484 complement(2350513..2350917) 1 NC_012943.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 2350917 8163484 TBMG_02167 Mycobacterium tuberculosis KZN 1435 glycine cleavage system protein H YP_003032131.1 2350513 R 478434 CDS YP_003032132.1 253799131 8163485 complement(2350955..2351833) 1 NC_012943.1 hypothetical protein 2351833 8163485 TBMG_02168 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032132.1 2350955 R 478434 CDS YP_003032133.1 253799132 8163486 complement(2351850..2352215) 1 NC_012943.1 hypothetical protein 2352215 8163486 TBMG_02169 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032133.1 2351850 R 478434 CDS YP_003032134.1 253799133 8163487 complement(2352244..2353173) 1 NC_012943.1 hypothetical protein 2353173 8163487 TBMG_02170 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032134.1 2352244 R 478434 CDS YP_003032135.1 253799134 8163488 complement(2353160..2353789) 1 NC_012943.1 CDP-diacylglycerol-glycerol-3-phosphate-3- phosphatidyltransferase pgsA2 2353789 8163488 TBMG_02171 Mycobacterium tuberculosis KZN 1435 CDP-diacylglycerol-glycerol-3-phosphate-3- phosphatidyltransferase pgsA2 YP_003032135.1 2353160 R 478434 CDS YP_003032136.1 253799135 8163489 complement(2353986..2356412) 1 NC_012943.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 2356412 8163489 TBMG_02172 Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit SecA YP_003032136.1 2353986 R 478434 CDS YP_003032137.1 253799136 8163490 complement(2356427..2358070) 1 NC_012943.1 hypothetical protein 2358070 8163490 TBMG_02173 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032137.1 2356427 R 478434 CDS YP_003032138.1 253799137 8163491 2358141..2360060 1 NC_012943.1 drugs-transport transmembrane ATP-binding protein ABC transporter 2360060 8163491 TBMG_02174 Mycobacterium tuberculosis KZN 1435 drugs-transport transmembrane ATP-binding protein ABC transporter YP_003032138.1 2358141 D 478434 CDS YP_003032139.1 253799138 8163492 2360135..2361691 1 NC_012943.1 PE-PGRS family protein 2361691 8163492 TBMG_04052 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032139.1 2360135 D 478434 CDS YP_003032140.1 253799139 8163493 complement(2361811..2363274) 1 NC_012943.1 hypothetical protein 2363274 8163493 TBMG_02177 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032140.1 2361811 R 478434 CDS YP_003032141.1 253799140 8163494 complement(2363909..2364613) 1 NC_012943.1 transcriptional regulator 2364613 8163494 TBMG_02178 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032141.1 2363909 R 478434 CDS YP_003032142.1 253799141 8163495 complement(2364676..2365341) 1 NC_012943.1 hypothetical protein 2365341 8163495 TBMG_02179 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032142.1 2364676 R 478434 CDS YP_003032143.1 253799142 8163496 complement(2365446..2366390) 1 NC_012943.1 membrane-bound C-5 sterol desaturase erg3 2366390 8163496 TBMG_02180 Mycobacterium tuberculosis KZN 1435 membrane-bound C-5 sterol desaturase erg3 YP_003032143.1 2365446 R 478434 CDS YP_003032144.1 253799143 8163497 2366757..2367188 1 NC_012943.1 hypothetical protein 2367188 8163497 TBMG_02181 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032144.1 2366757 D 478434 CDS YP_003032145.1 253799144 8163498 2367510..2368712 1 NC_012943.1 dehydrogenase 2368712 8163498 TBMG_02182 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003032145.1 2367510 D 478434 CDS YP_003032146.1 253799145 8163499 complement(2368722..2369426) 1 NC_012943.1 Mg2+ transport ATPase C mgtC 2369426 8163499 TBMG_02183 Mycobacterium tuberculosis KZN 1435 Mg2+ transport ATPase C mgtC YP_003032146.1 2368722 R 478434 CDS YP_003032147.1 253799146 8163500 complement(2369580..2369936) 1 NC_012943.1 hypothetical protein 2369936 8163500 TBMG_02184 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032147.1 2369580 R 478434 CDS YP_003032148.1 253799147 8163501 complement(2370181..2371593) 1 NC_012943.1 PPE family protein 2371593 8163501 TBMG_02185 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032148.1 2370181 R 478434 CDS YP_003032149.1 253799148 8163502 complement(2371719..2372951) 1 NC_012943.1 PPE family protein 2372951 8163502 TBMG_02186 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032149.1 2371719 R 478434 CDS YP_003032150.1 253799149 8163503 complement(2373272..2374483) 1 NC_012943.1 PPE family protein 2374483 8163503 TBMG_02187 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032150.1 2373272 R 478434 CDS YP_003032151.1 253799150 8163504 complement(2374498..2374797) 1 NC_012943.1 PE family protein 2374797 8163504 TBMG_02188 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032151.1 2374498 R 478434 CDS YP_003032152.1 253799151 8163505 2374835..2375182 1 NC_012943.1 hypothetical protein 2375182 8163505 TBMG_02189 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032152.1 2374835 D 478434 CDS YP_003032153.1 253799152 8163506 2375553..2375879 1 NC_012943.1 transposase 2375879 8163506 TBMG_02190 Mycobacterium tuberculosis KZN 1435 transposase YP_003032153.1 2375553 D 478434 CDS YP_003032154.1 253799153 8163507 2375930..2376814 1 NC_012943.1 transposase 2376814 8163507 TBMG_02191 Mycobacterium tuberculosis KZN 1435 transposase YP_003032154.1 2375930 D 478434 CDS YP_003032155.1 253799154 8163508 2376878..2377204 1 NC_012943.1 hypothetical protein 2377204 8163508 TBMG_02192 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032155.1 2376878 D 478434 CDS YP_003032156.1 253799155 8163509 2377352..2379304 1 NC_012943.1 PE-PGRS family protein 2379304 8163509 TBMG_02193 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032156.1 2377352 D 478434 CDS YP_003032157.1 253799156 8163510 complement(2379452..2380843) 1 NC_012943.1 PPE family protein 2380843 8163510 TBMG_02194 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032157.1 2379452 R 478434 CDS YP_003032158.1 253799157 8163511 complement(2380955..2382226) 1 NC_012943.1 PPE family protein 2382226 8163511 TBMG_02195 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032158.1 2380955 R 478434 CDS YP_003032159.1 253799158 8163512 complement(2382807..2384774) 1 NC_012943.1 PPE family protein 2384774 8163512 TBMG_02196 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032159.1 2382807 R 478434 CDS YP_003032160.1 253799159 8163513 complement(2384877..2385068) 1 NC_012943.1 hypothetical protein 2385068 8163513 TBMG_02197 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032160.1 2384877 R 478434 CDS YP_003032161.1 253799160 8163514 complement(2385695..2387527) 1 NC_012943.1 hypothetical protein 2387527 8163514 TBMG_02198 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032161.1 2385695 R 478434 CDS YP_003032162.1 253799161 8163515 complement(2387524..2388744) 1 NC_012943.1 hypothetical protein 2388744 8163515 TBMG_02199 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032162.1 2387524 R 478434 CDS YP_003032163.1 253799162 8163516 complement(2388741..2390498) 1 NC_012943.1 hypothetical protein 2390498 8163516 TBMG_02200 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032163.1 2388741 R 478434 CDS YP_003032164.1 253799163 8163517 complement(2390476..2391987) 1 NC_012943.1 hypothetical protein 2391987 8163517 TBMG_02201 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032164.1 2390476 R 478434 CDS YP_003032165.1 253799164 8163518 complement(2392259..2393161) 1 NC_012943.1 hypothetical protein 2393161 8163518 TBMG_02202 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032165.1 2392259 R 478434 CDS YP_003032166.1 253799165 8163519 complement(2393249..2393533) 1 NC_012943.1 esat-6 like protein esxN 2393533 8163519 TBMG_02203 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxN YP_003032166.1 2393249 R 478434 CDS YP_003032167.1 253799166 8163520 complement(2393584..2393703) 1 NC_012943.1 esat-6 like protein esxM 2393703 8163520 TBMG_04053 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxM YP_003032167.1 2393584 R 478434 CDS YP_003032168.1 253799167 8163521 complement(2393704..2393865) 1 NC_012943.1 esat-6 like protein esxM 2393865 8163521 TBMG_02204 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxM YP_003032168.1 2393704 R 478434 CDS YP_003032169.1 253799168 8163522 complement(2394024..2394341) 1 NC_012943.1 PE family protein 2394341 8163522 TBMG_02205 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032169.1 2394024 R 478434 CDS YP_003032170.1 253799169 8163523 complement(2394750..2395841) 1 NC_012943.1 PPE family protein 2395841 8163523 TBMG_02206 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032170.1 2394750 R 478434 CDS YP_003032171.1 253799170 8163524 complement(2395914..2396216) 1 NC_012943.1 hypothetical protein 2396216 8163524 TBMG_02207 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032171.1 2395914 R 478434 CDS YP_003032172.1 253799171 8163525 complement(2396256..2397437) 1 NC_012943.1 PPE family protein 2397437 8163525 TBMG_02208 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032172.1 2396256 R 478434 CDS YP_003032173.1 253799172 8163526 complement(2397451..2397750) 1 NC_012943.1 PE family protein 2397750 8163526 TBMG_02209 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032173.1 2397451 R 478434 CDS YP_003032174.1 253799173 8163527 complement(2397829..2399046) 1 NC_012943.1 PPE family protein 2399046 8163527 TBMG_02210 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032174.1 2397829 R 478434 CDS YP_003032175.1 253799174 8163528 complement(2399196..2399399) 1 NC_012943.1 ferredoxin 2399399 8163528 TBMG_02211 Mycobacterium tuberculosis KZN 1435 ferredoxin YP_003032175.1 2399196 R 478434 CDS YP_003032176.1 253799175 8163529 2399599..2400780 1 NC_012943.1 cytochrome P450 143 cyp143 2400780 8163529 TBMG_02212 Mycobacterium tuberculosis KZN 1435 cytochrome P450 143 cyp143 YP_003032176.1 2399599 D 478434 CDS YP_003032177.1 253799176 8163530 complement(2400795..2404970) 1 NC_012943.1 FtsK/SpoIIIE family protein 2404970 8163530 TBMG_02213 Mycobacterium tuberculosis KZN 1435 FtsK/SpoIIIE family protein YP_003032177.1 2400795 R 478434 CDS YP_003032178.1 253799177 8163531 complement(2404967..2406487) 1 NC_012943.1 hypothetical protein 2406487 8163531 TBMG_02214 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032178.1 2404967 R 478434 CDS YP_003032179.1 253799178 8163532 2406751..2408109 1 NC_012943.1 truncated CDS; 4-alpha-glucanotransferase 2408109 8163532 TBMG_02215 Mycobacterium tuberculosis KZN 1435 4-alpha-glucanotransferase YP_003032179.1 2406751 D 478434 CDS YP_003032180.1 253799179 8163533 complement(2408966..2409529) 1 NC_012943.1 hypothetical protein 2409529 8163533 TBMG_02216 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032180.1 2408966 R 478434 CDS YP_003032181.1 253799180 8163534 2409749..2411542 1 NC_012943.1 hypothetical protein 2411542 8163534 TBMG_04054 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032181.1 2409749 D 478434 CDS YP_003032182.1 253799181 8163535 2411641..2412147 1 NC_012943.1 hypothetical protein 2412147 8163535 TBMG_02217 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032182.1 2411641 D 478434 CDS YP_003032183.1 253799182 8163536 complement(2412268..2413572) 1 NC_012943.1 cytochrome P450 144 cyp144 2413572 8163536 TBMG_02218 Mycobacterium tuberculosis KZN 1435 cytochrome P450 144 cyp144 YP_003032183.1 2412268 R 478434 CDS YP_003032184.1 253799183 8163537 2413673..2414233 1 NC_012943.1 transcriptional regulator 2414233 8163537 TBMG_02219 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032184.1 2413673 D 478434 CDS YP_003032185.1 253799184 8163538 complement(2414238..2415056) 1 NC_012943.1 hypothetical protein 2415056 8163538 TBMG_02220 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032185.1 2414238 R 478434 CDS YP_003032186.1 253799185 8163539 complement(2415056..2416396) 1 NC_012943.1 oxidoreductase 2416396 8163539 TBMG_02221 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032186.1 2415056 R 478434 CDS YP_003032187.1 253799186 8163540 2416462..2417208 1 NC_012943.1 transcriptional regulator 2417208 8163540 TBMG_02222 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032187.1 2416462 D 478434 CDS YP_003032188.1 253799187 8163541 complement(2417281..2417592) 1 NC_012943.1 hypothetical protein 2417592 8163541 TBMG_02223 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032188.1 2417281 R 478434 CDS YP_003032189.1 253799188 8162051 complement(2417781..2419067) 1 NC_012943.1 oxidoreductase 2419067 8162051 TBMG_02224 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032189.1 2417781 R 478434 CDS YP_003032190.1 253799189 8162052 complement(2419064..2420350) 1 NC_012943.1 hypothetical protein 2420350 8162052 TBMG_02225 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032190.1 2419064 R 478434 CDS YP_003032191.1 253799190 8162053 complement(2420358..2421593) 1 NC_012943.1 hypothetical protein 2421593 8162053 TBMG_02226 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032191.1 2420358 R 478434 CDS YP_003032192.1 253799191 8161730 complement(2421758..2423614) 1 NC_012943.1 PE-PGRS family protein 2423614 8161730 TBMG_02227 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032192.1 2421758 R 478434 CDS YP_003032193.1 253799192 8164000 complement(2423795..2424154) 1 NC_012943.1 hypothetical protein 2424154 8164000 TBMG_02228 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032193.1 2423795 R 478434 CDS YP_003032194.1 253799193 8164001 complement(2424222..2424497) 1 NC_012943.1 hypothetical protein 2424497 8164001 TBMG_02229 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032194.1 2424222 R 478434 CDS YP_003032195.1 253799194 8164002 2424871..2425086 1 NC_012943.1 transposase 2425086 8164002 TBMG_02230 Mycobacterium tuberculosis KZN 1435 transposase YP_003032195.1 2424871 D 478434 CDS YP_003032196.1 253799195 8164003 2425713..2426969 1 NC_012943.1 hypothetical protein 2426969 8164003 TBMG_02231 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032196.1 2425713 D 478434 CDS YP_003032197.1 253799196 8164004 2427380..2427847 1 NC_012943.1 hypothetical protein 2427847 8164004 TBMG_02232 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032197.1 2427380 D 478434 CDS YP_003032198.1 253799197 8164005 2427987..2428775 1 NC_012943.1 hypothetical protein 2428775 8164005 TBMG_02233 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032198.1 2427987 D 478434 CDS YP_003032199.1 253799198 8164006 2428775..2429158 1 NC_012943.1 hypothetical protein 2429158 8164006 TBMG_02234 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032199.1 2428775 D 478434 CDS YP_003032200.1 253799199 8164007 complement(2429168..2430676) 1 NC_012943.1 hypothetical protein 2430676 8164007 TBMG_02235 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032200.1 2429168 R 478434 CDS YP_003032201.1 253799200 8164008 2431144..2433996 1 NC_012943.1 PE-PGRS family protein 2433996 8164008 TBMG_04055 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032201.1 2431144 D 478434 CDS YP_003032202.1 253799201 8164009 complement(2434263..2434802) 1 NC_012943.1 cutinase cut1 2434802 8164009 TBMG_02238 Mycobacterium tuberculosis KZN 1435 cutinase cut1 YP_003032202.1 2434263 R 478434 CDS YP_003032203.1 253799202 8164011 2434801..2435127 1 NC_012943.1 transposase 2435127 8164011 TBMG_02239 Mycobacterium tuberculosis KZN 1435 transposase YP_003032203.1 2434801 D 478434 CDS YP_003032204.1 253799203 8164010 2435178..2436062 1 NC_012943.1 transposase 2436062 8164010 TBMG_02240 Mycobacterium tuberculosis KZN 1435 transposase YP_003032204.1 2435178 D 478434 CDS YP_003032205.1 253799204 8164012 2436240..2437751 1 NC_012943.1 hypothetical protein 2437751 8164012 TBMG_02241 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032205.1 2436240 D 478434 CDS YP_003032206.1 253799205 8164013 2437955..2441032 1 NC_012943.1 PPE family protein 2441032 8164013 TBMG_02242 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032206.1 2437955 D 478434 CDS YP_003032207.1 253799206 8164014 complement(2441067..2441516) 1 NC_012943.1 hypothetical protein 2441516 8164014 TBMG_02243 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032207.1 2441067 R 478434 CDS YP_003032208.1 253799207 8164015 complement(2441643..2443025) 1 NC_012943.1 hypothetical protein 2443025 8164015 TBMG_02244 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032208.1 2441643 R 478434 CDS YP_003032209.1 253799208 8164016 2443079..2444677 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2444677 8164016 TBMG_02245 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003032209.1 2443079 D 478434 CDS YP_003032210.1 253799209 8164017 2444761..2445318 1 NC_012943.1 hypothetical protein 2445318 8164017 TBMG_02246 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032210.1 2444761 D 478434 CDS YP_003032211.1 253799210 8164018 complement(2445315..2446046) 1 NC_012943.1 hypothetical protein 2446046 8164018 TBMG_02247 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032211.1 2445315 R 478434 CDS YP_003032212.1 253799211 8164019 complement(2446419..2449016) 1 NC_012943.1 transmembrane ATP-binding protein ABC transporter 2449016 8164019 TBMG_02248 Mycobacterium tuberculosis KZN 1435 transmembrane ATP-binding protein ABC transporter YP_003032212.1 2446419 R 478434 CDS YP_003032213.1 253799212 8164020 complement(2449078..2450508) 1 NC_012943.1 anchored-membrane serine/threonine-protein kinase pknF 2450508 8164020 TBMG_02249 Mycobacterium tuberculosis KZN 1435 anchored-membrane serine/threonine-protein kinase pknF YP_003032213.1 2449078 R 478434 CDS YP_003032214.1 253799213 8164021 2450655..2451266 1 NC_012943.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 2451266 8164021 TBMG_02250 Mycobacterium tuberculosis KZN 1435 isopentenyl-diphosphate delta-isomerase YP_003032214.1 2450655 D 478434 CDS YP_003032215.1 253799214 8164022 2451256..2451657 1 NC_012943.1 hypothetical protein 2451657 8164022 TBMG_02251 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032215.1 2451256 D 478434 CDS YP_003032216.1 253799215 8164023 complement(2451942..2453642) 1 NC_012943.1 Ser/Thr protein kinase 2453642 8164023 TBMG_02252 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003032216.1 2451942 R 478434 CDS YP_003032217.1 253799216 8164024 complement(2453736..2454473) 1 NC_012943.1 hypothetical protein 2454473 8164024 TBMG_02253 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032217.1 2453736 R 478434 CDS YP_003032218.1 253799217 8164025 complement(2454481..2454729) 1 NC_012943.1 toxin 2454729 8164025 TBMG_02254 Mycobacterium tuberculosis KZN 1435 toxin YP_003032218.1 2454481 R 478434 CDS YP_003032219.1 253799218 8164026 complement(2454729..2454941) 1 NC_012943.1 antitoxin 2454941 8164026 TBMG_02255 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032219.1 2454729 R 478434 CDS YP_003032220.1 253799219 8164027 2455009..2456691 1 NC_012943.1 hypothetical protein 2456691 8164027 TBMG_02256 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032220.1 2455009 D 478434 CDS YP_003032221.1 253799220 8164028 complement(2456705..2457166) 1 NC_012943.1 hypothetical protein 2457166 8164028 TBMG_02257 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032221.1 2456705 R 478434 CDS YP_003032222.1 253799221 8164029 2457276..2458463 1 NC_012943.1 nitrate/nitrite transporter narK2 2458463 8164029 TBMG_02258 Mycobacterium tuberculosis KZN 1435 nitrate/nitrite transporter narK2 YP_003032222.1 2457276 D 478434 CDS YP_003032223.1 253799222 8164030 2458460..2460418 1 NC_012943.1 nitrate reductase narX 2460418 8164030 TBMG_02259 Mycobacterium tuberculosis KZN 1435 nitrate reductase narX YP_003032223.1 2458460 D 478434 CDS YP_003032224.1 253799223 8164031 2460517..2460759 1 NC_012943.1 hypothetical protein 2460759 8164031 TBMG_02260 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032224.1 2460517 D 478434 CDS YP_003032225.1 253799224 8164032 2460762..2461355 1 NC_012943.1 hypothetical protein 2461355 8164032 TBMG_02261 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032225.1 2460762 D 478434 CDS YP_003032226.1 253799225 8164033 2461630..2461872 1 NC_012943.1 hypothetical protein 2461872 8164033 TBMG_02262 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032226.1 2461630 D 478434 CDS YP_003032227.1 253799226 8164034 2462159..2462791 1 NC_012943.1 hypothetical protein 2462791 8164034 TBMG_02263 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032227.1 2462159 D 478434 CDS YP_003032228.1 253799227 8164035 2462855..2463403 1 NC_012943.1 hypothetical protein 2463403 8164035 TBMG_02264 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032228.1 2462855 D 478434 CDS YP_003032229.1 253799228 8164036 complement(2463413..2464969) 1 NC_012943.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase 2464969 gabD2 8164036 gabD2 Mycobacterium tuberculosis KZN 1435 succinic semialdehyde dehydrogenase YP_003032229.1 2463413 R 478434 CDS YP_003032230.1 253799229 8164037 2465335..2466954 1 NC_012943.1 penicillin-binding protein 2466954 8164037 TBMG_02266 Mycobacterium tuberculosis KZN 1435 penicillin-binding protein YP_003032230.1 2465335 D 478434 CDS YP_003032231.1 253799230 8164038 2466976..2467167 1 NC_012943.1 cell wall surface anchor family protein 2467167 8164038 TBMG_04056 Mycobacterium tuberculosis KZN 1435 cell wall surface anchor family protein YP_003032231.1 2466976 D 478434 CDS YP_003032232.1 253799231 8164039 2467134..2468072 1 NC_012943.1 hypothetical protein 2468072 8164039 TBMG_04057 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032232.1 2467134 D 478434 CDS YP_003032233.1 253799232 8164040 2468069..2468839 1 NC_012943.1 hypothetical protein 2468839 8164040 TBMG_02268 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032233.1 2468069 D 478434 CDS YP_003032234.1 253799233 8164041 complement(2468864..2469433) 1 NC_012943.1 hypothetical protein 2469433 8164041 TBMG_02269 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032234.1 2468864 R 478434 CDS YP_003032235.1 253799234 8164042 complement(2469466..2470851) 1 NC_012943.1 oxidoreductase 2470851 8164042 TBMG_02270 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032235.1 2469466 R 478434 CDS YP_003032236.1 253799235 8164043 2470952..2471662 1 NC_012943.1 hypothetical protein 2471662 8164043 TBMG_02271 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032236.1 2470952 D 478434 CDS YP_003032237.1 253799236 8164044 2471652..2472071 1 NC_012943.1 hypothetical protein 2472071 8164044 TBMG_02272 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032237.1 2471652 D 478434 CDS YP_003032238.1 253799237 8164045 complement(2472114..2473361) 1 NC_012943.1 hydrolase 2473361 8164045 TBMG_02273 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003032238.1 2472114 R 478434 CDS YP_003032239.1 253799238 8164046 complement(2473358..2474842) 1 NC_012943.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase-like protein 2474842 8164046 TBMG_02274 Mycobacterium tuberculosis KZN 1435 biotin carboxylase-like protein YP_003032239.1 2473358 R 478434 CDS YP_003032240.1 253799239 8164047 2475060..2475287 1 NC_012943.1 antitoxin 2475287 8164047 TBMG_04058 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032240.1 2475060 D 478434 CDS YP_003032241.1 253799240 8164048 2475284..2475673 1 NC_012943.1 toxin 2475673 8164048 TBMG_02275 Mycobacterium tuberculosis KZN 1435 toxin YP_003032241.1 2475284 D 478434 CDS YP_003032242.1 253799241 8164050 complement(2476179..2476286) 1 NC_012943.1 hypothetical protein 2476286 8164050 TBMG_04059 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032242.1 2476179 R 478434 CDS YP_003032243.1 253799242 8164051 complement(2476283..2477062) 1 NC_012943.1 transcriptional regulator 2477062 8164051 TBMG_02276 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032243.1 2476283 R 478434 CDS YP_003032244.1 253799243 8164052 complement(2477076..2477894) 1 NC_012943.1 hypothetical protein 2477894 8164052 TBMG_02277 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032244.1 2477076 R 478434 CDS YP_003032245.1 253799244 8164053 complement(2477979..2478296) 1 NC_012943.1 hypothetical protein 2478296 8164053 TBMG_02278 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032245.1 2477979 R 478434 CDS YP_003032246.1 253799245 8164054 complement(2478296..2479126) 1 NC_012943.1 hypothetical protein 2479126 8164054 TBMG_02279 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032246.1 2478296 R 478434 CDS YP_003032247.1 253799246 8164055 complement(2479129..2480043) 1 NC_012943.1 3-hydroxybutyryl-CoA dehydrogenase 2480043 8164055 TBMG_02280 Mycobacterium tuberculosis KZN 1435 3-hydroxybutyryl-CoA dehydrogenase YP_003032247.1 2479129 R 478434 CDS YP_003032248.1 253799247 8164056 complement(2480037..2480849) 1 NC_012943.1 oxidoreductase 2480849 8164056 TBMG_02281 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032248.1 2480037 R 478434 CDS YP_003032249.1 253799248 8164057 complement(2481023..2482414) 1 NC_012943.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2482414 engA 8164057 engA Mycobacterium tuberculosis KZN 1435 GTP-binding protein EngA YP_003032249.1 2481023 R 478434 CDS YP_003032250.1 253799249 8164058 complement(2482411..2483103) 1 NC_012943.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 2483103 cmk 8164058 cmk Mycobacterium tuberculosis KZN 1435 cytidylate kinase YP_003032250.1 2482411 R 478434 CDS YP_003032251.1 253799250 8164059 complement(2483100..2483864) 1 NC_012943.1 hypothetical protein 2483864 8164059 TBMG_02284 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032251.1 2483100 R 478434 CDS YP_003032252.1 253799251 8164060 complement(2483861..2484556) 1 NC_012943.1 hypothetical protein 2484556 8164060 TBMG_02285 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032252.1 2483861 R 478434 CDS YP_003032253.1 253799252 8164061 complement(2484553..2485389) 1 NC_012943.1 ScpA/B family protein 2485389 8164061 TBMG_02286 Mycobacterium tuberculosis KZN 1435 ScpA/B family protein YP_003032253.1 2484553 R 478434 CDS YP_003032254.1 253799253 8164062 complement(2485386..2486342) 1 NC_012943.1 initiation inhibitor protein 2486342 8164062 TBMG_02287 Mycobacterium tuberculosis KZN 1435 initiation inhibitor protein YP_003032254.1 2485386 R 478434 CDS YP_003032255.1 253799254 8164063 complement(2486360..2487820) 1 NC_012943.1 hypothetical protein 2487820 8164063 TBMG_02288 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032255.1 2486360 R 478434 CDS YP_003032256.1 253799255 8164064 2488053..2488220 1 NC_012943.1 hypothetical protein 2488220 8164064 TBMG_02289 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032256.1 2488053 D 478434 CDS YP_003032257.1 253799256 8164065 2488824..2490008 1 NC_012943.1 PPE family protein 2490008 8164065 TBMG_02290 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032257.1 2488824 D 478434 CDS YP_003032258.1 253799257 8164066 2490048..2491205 1 NC_012943.1 PPE family protein 2491205 8164066 TBMG_02291 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032258.1 2490048 D 478434 CDS YP_003032259.1 253799258 8164067 2491246..2492916 1 NC_012943.1 D-serine/alanine/glycine transporter cycA 2492916 8164067 TBMG_02292 Mycobacterium tuberculosis KZN 1435 D-serine/alanine/glycine transporter cycA YP_003032259.1 2491246 D 478434 CDS YP_003032260.1 253799259 8164068 2492870..2493571 1 NC_012943.1 catechol-O-methyltransferase 2493571 8164068 TBMG_02293 Mycobacterium tuberculosis KZN 1435 catechol-O-methyltransferase YP_003032260.1 2492870 D 478434 CDS YP_003032261.1 253799260 8164069 2494127..2495491 1 NC_012943.1 hypothetical protein 2495491 8164069 TBMG_02294 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032261.1 2494127 D 478434 CDS YP_003032262.1 253799261 8164070 complement(2495565..2496500) 1 NC_012943.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 2496500 xerD 8164070 xerD Mycobacterium tuberculosis KZN 1435 site-specific tyrosine recombinase XerD YP_003032262.1 2495565 R 478434 CDS YP_003032263.1 253799262 8164071 complement(2496497..2497120) 1 NC_012943.1 hypothetical protein 2497120 8164071 TBMG_02296 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032263.1 2496497 R 478434 CDS YP_003032264.1 253799263 8164072 complement(2497113..2498873) 1 NC_012943.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2498873 pyrG 8164072 pyrG Mycobacterium tuberculosis KZN 1435 CTP synthetase YP_003032264.1 2497113 R 478434 CDS YP_003032265.1 253799264 8164073 complement(2499013..2499957) 1 NC_012943.1 hypothetical protein 2499957 8164073 TBMG_02298 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032265.1 2499013 R 478434 CDS YP_003032266.1 253799265 8164074 complement(2499979..2501160) 1 NC_012943.1 hypothetical protein 2501160 8164074 TBMG_02299 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032266.1 2499979 R 478434 CDS YP_003032267.1 253799266 8164075 complement(2501256..2503019) 1 NC_012943.1 DNA repair protein recN 2503019 8164075 TBMG_02300 Mycobacterium tuberculosis KZN 1435 DNA repair protein recN YP_003032267.1 2501256 R 478434 CDS YP_003032268.1 253799267 8164076 complement(2503033..2503956) 1 NC_012943.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2503956 ppnK 8164076 ppnK Mycobacterium tuberculosis KZN 1435 inorganic polyphosphate/ATP-NAD kinase YP_003032268.1 2503033 R 478434 CDS YP_003032269.1 253799268 8164077 complement(2503956..2504762) 1 NC_012943.1 cytotoxin/hemolysin tlyA 2504762 8164077 TBMG_02302 Mycobacterium tuberculosis KZN 1435 cytotoxin/hemolysin tlyA YP_003032269.1 2503956 R 478434 CDS YP_003032270.1 253799269 8164078 complement(2504943..2506004) 1 NC_012943.1 phosphatase 2506004 8164078 TBMG_02303 Mycobacterium tuberculosis KZN 1435 phosphatase YP_003032270.1 2504943 R 478434 CDS YP_003032271.1 253799270 8164079 complement(2506001..2506753) 1 NC_012943.1 hypothetical protein 2506753 8164079 TBMG_02304 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032271.1 2506001 R 478434 CDS YP_003032272.1 253799271 8163623 complement(2506792..2507175) 1 NC_012943.1 hypothetical protein 2507175 8163623 TBMG_02305 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032272.1 2506792 R 478434 CDS YP_003032273.1 253799272 8163624 complement(2507826..2509100) 1 NC_012943.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2509100 8163624 TBMG_02306 Mycobacterium tuberculosis KZN 1435 tyrosyl-tRNA synthetase YP_003032273.1 2507826 R 478434 CDS YP_003032274.1 253799273 8160578 complement(2509112..2509723) 1 NC_012943.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 2509723 8160578 TBMG_02307 Mycobacterium tuberculosis KZN 1435 3-methyladenine DNA glycosylase YP_003032274.1 2509112 R 478434 CDS YP_003032275.1 253799274 8160579 2509782..2510549 1 NC_012943.1 ABC transporter ATP-binding protein 2510549 8160579 TBMG_02308 Mycobacterium tuberculosis KZN 1435 ABC transporter ATP-binding protein YP_003032275.1 2509782 D 478434 CDS YP_003032276.1 253799275 8160580 2510621..2511301 1 NC_012943.1 hypothetical protein 2511301 8160580 TBMG_02309 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032276.1 2510621 D 478434 CDS YP_003032277.1 253799276 8160581 2511303..2511926 1 NC_012943.1 hypothetical protein 2511926 8160581 TBMG_02310 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032277.1 2511303 D 478434 CDS YP_003032278.1 253799277 8160582 complement(2511892..2512116) 1 NC_012943.1 hypothetical protein 2512116 8160582 TBMG_04060 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032278.1 2511892 R 478434 CDS YP_003032279.1 253799278 8160583 complement(2512109..2515108) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2515108 8160583 TBMG_02311 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003032279.1 2512109 R 478434 CDS YP_003032280.1 253799279 8160584 complement(2515382..2516299) 1 NC_012943.1 hypothetical protein 2516299 8160584 TBMG_02312 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032280.1 2515382 R 478434 CDS YP_003032281.1 253799280 8160585 complement(2516460..2517455) 1 NC_012943.1 molybdopterin biosynthesis protein moeX 2517455 8160585 TBMG_02313 Mycobacterium tuberculosis KZN 1435 molybdopterin biosynthesis protein moeX YP_003032281.1 2516460 R 478434 CDS YP_003032282.1 253799281 8160586 complement(2517449..2518273) 1 NC_012943.1 hypothetical protein 2518273 8160586 TBMG_02314 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032282.1 2517449 R 478434 CDS YP_003032283.1 253799282 8160587 complement(2518282..2519403) 1 NC_012943.1 acyl-CoA dehydrogenase 2519403 8160587 TBMG_02315 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003032283.1 2518282 R 478434 CDS YP_003032284.1 253799283 8160588 complement(2519403..2520311) 1 NC_012943.1 hypothetical protein 2520311 8160588 TBMG_02316 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032284.1 2519403 R 478434 CDS YP_003032285.1 253799284 8160589 complement(2520406..2520954) 1 NC_012943.1 lipoprotein dsbF 2520954 8160589 TBMG_02317 Mycobacterium tuberculosis KZN 1435 lipoprotein dsbF YP_003032285.1 2520406 R 478434 CDS YP_003032286.1 253799285 8160590 complement(2520951..2521655) 1 NC_012943.1 hypothetical protein 2521655 8160590 TBMG_02318 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032286.1 2520951 R 478434 CDS YP_003032287.1 253799286 8160591 2521727..2522461 1 NC_012943.1 transcriptional regulator 2522461 8160591 TBMG_02319 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032287.1 2521727 D 478434 CDS YP_003032288.1 253799287 8160592 2522786..2523442 1 NC_012943.1 transcriptional regulator 2523442 8160592 TBMG_02320 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032288.1 2522786 D 478434 CDS YP_003032289.1 253799288 8160593 2523470..2524402 1 NC_012943.1 hypothetical protein 2524402 8160593 TBMG_02321 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032289.1 2523470 D 478434 CDS YP_003032290.1 253799289 8160594 2524495..2525826 1 NC_012943.1 membrane transporter 2525826 8160594 TBMG_02322 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003032290.1 2524495 D 478434 CDS YP_003032291.1 253799290 8160595 complement(2525835..2526230) 1 NC_012943.1 hypothetical protein 2526230 8160595 TBMG_02323 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032291.1 2525835 R 478434 CDS YP_003032292.1 253799291 8160596 complement(2526235..2526582) 1 NC_012943.1 hypothetical protein 2526582 8160596 TBMG_02324 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032292.1 2526235 R 478434 CDS YP_003032293.1 253799292 8160597 complement(2526615..2526977) 1 NC_012943.1 hypothetical protein 2526977 8160597 TBMG_02325 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032293.1 2526615 R 478434 CDS YP_003032294.1 253799293 8160598 2527360..2529135 1 NC_012943.1 macrolide-transport ATP-binding protein ABC transporter 2529135 8160598 TBMG_02326 Mycobacterium tuberculosis KZN 1435 macrolide-transport ATP-binding protein ABC transporter YP_003032294.1 2527360 D 478434 CDS YP_003032295.1 253799294 8160599 2529150..2530442 1 NC_012943.1 cytochrome P450 139 cyp139 2530442 8160599 TBMG_02327 Mycobacterium tuberculosis KZN 1435 cytochrome P450 139 cyp139 YP_003032295.1 2529150 D 478434 CDS YP_003032296.1 253799295 8160600 complement(2530425..2531486) 1 NC_012943.1 chalcone synthase pks11 2531486 8160600 TBMG_02328 Mycobacterium tuberculosis KZN 1435 chalcone synthase pks11 YP_003032296.1 2530425 R 478434 CDS YP_003032297.1 253799296 8160601 complement(2531633..2534686) 1 NC_012943.1 polyketide synthase 2534686 8160601 TBMG_02329 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003032297.1 2531633 R 478434 CDS YP_003032298.1 253799297 8160602 complement(2534692..2536224) 1 NC_012943.1 polyketide synthase 2536224 8160602 TBMG_02330 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003032298.1 2534692 R 478434 CDS YP_003032299.1 253799298 8160603 complement(2536200..2541008) 1 NC_012943.1 polyketide synthase 2541008 8160603 TBMG_02331 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003032299.1 2536200 R 478434 CDS YP_003032300.1 253799299 8160604 complement(2541028..2547408) 1 NC_012943.1 polyketide synthase 2547408 8160604 TBMG_02332 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003032300.1 2541028 R 478434 CDS YP_003032301.1 253799300 8160605 complement(2547491..2548552) 1 NC_012943.1 chalcone synthase pks10 2548552 8160605 TBMG_02333 Mycobacterium tuberculosis KZN 1435 chalcone synthase pks10 YP_003032301.1 2547491 R 478434 CDS YP_003032302.1 253799301 8160606 complement(2548661..2550073) 1 NC_012943.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 2550073 8160606 TBMG_02334 Mycobacterium tuberculosis KZN 1435 argininosuccinate lyase YP_003032302.1 2548661 R 478434 CDS YP_003032303.1 253799302 8160607 complement(2550153..2551349) 1 NC_012943.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 2551349 8160607 TBMG_02335 Mycobacterium tuberculosis KZN 1435 argininosuccinate synthase YP_003032303.1 2550153 R 478434 CDS YP_003032304.1 253799303 8160608 complement(2551358..2551888) 1 NC_012943.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 2551888 8160608 TBMG_02336 Mycobacterium tuberculosis KZN 1435 arginine repressor ArgR YP_003032304.1 2551358 R 478434 CDS YP_003032305.1 253799304 8160609 complement(2551867..2552790) 1 NC_012943.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 2552790 8160609 TBMG_02337 Mycobacterium tuberculosis KZN 1435 ornithine carbamoyltransferase YP_003032305.1 2551867 R 478434 CDS YP_003032306.1 253799305 8160610 complement(2552787..2553989) 1 NC_012943.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 2553989 argD 8160610 argD Mycobacterium tuberculosis KZN 1435 acetylornithine aminotransferase YP_003032306.1 2552787 R 478434 CDS YP_003032307.1 253799306 8160611 complement(2553986..2554870) 1 NC_012943.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 2554870 8160611 TBMG_02339 Mycobacterium tuberculosis KZN 1435 acetylglutamate kinase YP_003032307.1 2553986 R 478434 CDS YP_003032308.1 253799307 8160612 complement(2554867..2556081) 1 NC_012943.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 2556081 argJ 8160612 argJ Mycobacterium tuberculosis KZN 1435 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_003032308.1 2554867 R 478434 CDS YP_003032309.1 253799308 8160613 complement(2556078..2557136) 1 NC_012943.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 2557136 argC 8160613 argC Mycobacterium tuberculosis KZN 1435 N-acetyl-gamma-glutamyl-phosphate reductase YP_003032309.1 2556078 R 478434 CDS YP_003032310.1 253799309 8160614 2557330..2560365 1 NC_012943.1 PE-PGRS family protein 2560365 8160614 TBMG_02342 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032310.1 2557330 D 478434 CDS YP_003032311.1 253799310 8160615 complement(2560459..2562954) 1 NC_012943.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2562954 pheT 8160615 pheT Mycobacterium tuberculosis KZN 1435 phenylalanyl-tRNA synthetase subunit beta YP_003032311.1 2560459 R 478434 CDS YP_003032312.1 253799311 8160616 complement(2562954..2564012) 1 NC_012943.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2564012 pheS 8160616 pheS Mycobacterium tuberculosis KZN 1435 phenylalanyl-tRNA synthetase subunit alpha YP_003032312.1 2562954 R 478434 CDS YP_003032313.1 253799312 8160617 complement(2564175..2564981) 1 NC_012943.1 hypothetical protein 2564981 8160617 TBMG_02345 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032313.1 2564175 R 478434 CDS YP_003032314.1 253799313 8160618 complement(2564988..2565938) 1 NC_012943.1 hypothetical protein 2565938 8160618 TBMG_02346 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032314.1 2564988 R 478434 CDS YP_003032315.1 253799314 8160619 complement(2566016..2566948) 1 NC_012943.1 PE family protein 2566948 8160619 TBMG_02347 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032315.1 2566016 R 478434 CDS YP_003032316.1 253799315 8160620 2567258..2568313 1 NC_012943.1 hypothetical protein 2568313 8160620 TBMG_02348 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032316.1 2567258 D 478434 CDS YP_003032317.1 253799316 8160621 complement(2568324..2569106) 1 NC_012943.1 23S rRNA methyltransferase 2569106 8160621 TBMG_02349 Mycobacterium tuberculosis KZN 1435 23S rRNA methyltransferase YP_003032317.1 2568324 R 478434 CDS YP_003032318.1 253799317 8160622 complement(2569139..2569528) 1 NC_012943.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2569528 rplT 8160622 rplT Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L20 YP_003032318.1 2569139 R 478434 CDS YP_003032319.1 253799318 8160623 complement(2569590..2569784) 1 NC_012943.1 50S ribosomal protein L35 2569784 rpmI 8160623 rpmI Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L35 YP_003032319.1 2569590 R 478434 CDS YP_003032320.1 253799319 8160624 complement(2569834..2570388) 1 NC_012943.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2570388 infC 8160624 infC Mycobacterium tuberculosis KZN 1435 translation initiation factor IF-3 YP_003032320.1 2569834 R 478434 CDS YP_003032321.1 253799320 8160625 2570671..2574195 1 NC_012943.1 catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 2574195 lysS 8160625 lysS Mycobacterium tuberculosis KZN 1435 lysyl-tRNA synthetase YP_003032321.1 2570671 D 478434 CDS YP_003032322.1 253799321 8160626 2574254..2574529 1 NC_012943.1 hypothetical protein 2574529 8160626 TBMG_04061 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032322.1 2574254 D 478434 CDS YP_003032323.1 253799322 8160627 2574542..2575723 1 NC_012943.1 hypothetical protein 2575723 8160627 TBMG_02354 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032323.1 2574542 D 478434 CDS YP_003032324.1 253799323 8160628 2575739..2575996 1 NC_012943.1 hypothetical protein 2575996 8160628 TBMG_02355 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032324.1 2575739 D 478434 CDS YP_003032325.1 253799324 8160629 complement(2576053..2578971) 1 NC_012943.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 2578971 uvrA 8160629 uvrA Mycobacterium tuberculosis KZN 1435 excinuclease ABC subunit A YP_003032325.1 2576053 R 478434 CDS YP_003032326.1 253799325 8160630 2579020..2579814 1 NC_012943.1 hypothetical protein 2579814 8160630 TBMG_02357 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032326.1 2579020 D 478434 CDS YP_003032327.1 253799326 8160631 complement(2579821..2580261) 1 NC_012943.1 hypothetical protein 2580261 8160631 TBMG_02358 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032327.1 2579821 R 478434 CDS YP_003032328.1 253799327 8160632 2580443..2582140 1 NC_012943.1 hypothetical protein 2582140 8160632 TBMG_02359 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032328.1 2580443 D 478434 CDS YP_003032329.1 253799328 8160633 complement(2582129..2583544) 1 NC_012943.1 hypothetical protein 2583544 8160633 TBMG_02360 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032329.1 2582129 R 478434 CDS YP_003032330.1 253799329 8160634 complement(2583541..2585760) 1 NC_012943.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 2585760 8160634 TBMG_02361 Mycobacterium tuberculosis KZN 1435 excinuclease ABC subunit B YP_003032330.1 2583541 R 478434 CDS YP_003032331.1 253799330 8160635 2585882..2586325 1 NC_012943.1 hypothetical protein 2586325 8160635 TBMG_02362 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032331.1 2585882 D 478434 CDS YP_003032332.1 253799331 8160636 complement(2586476..2587699) 1 NC_012943.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain; dephospho-CoA kinase/protein folding accessory domain-containing protein 2587699 coaE 8160636 coaE Mycobacterium tuberculosis KZN 1435 dephospho-CoA kinase/protein folding accessory domain-containing protein YP_003032332.1 2586476 R 478434 CDS YP_003032333.1 253799332 8160637 complement(2587725..2589170) 1 NC_012943.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 2589170 rpsA 8160637 rpsA Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S1 YP_003032333.1 2587725 R 478434 CDS YP_003032334.1 253799333 8160638 complement(2589333..2592047) 1 NC_012943.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 2592047 8160638 TBMG_02365 Mycobacterium tuberculosis KZN 1435 DNA polymerase I YP_003032334.1 2589333 R 478434 CDS YP_003032335.1 253799334 8160639 2592151..2592642 1 NC_012943.1 hypothetical protein 2592642 8160639 TBMG_02366 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032335.1 2592151 D 478434 CDS YP_003032336.1 253799335 8160640 2592639..2593847 1 NC_012943.1 lipid-transfer protein 2593847 8160640 TBMG_02367 Mycobacterium tuberculosis KZN 1435 lipid-transfer protein YP_003032336.1 2592639 D 478434 CDS YP_003032337.1 253799336 8160641 complement(2593915..2594541) 1 NC_012943.1 two component system transcriptional regulator 2594541 8160641 TBMG_02368 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator YP_003032337.1 2593915 R 478434 CDS YP_003032338.1 253799337 8160643 2594767..2596098 1 NC_012943.1 membrane-anchored adenylyl cyclase cya 2596098 8160643 TBMG_02369 Mycobacterium tuberculosis KZN 1435 membrane-anchored adenylyl cyclase cya YP_003032338.1 2594767 D 478434 CDS YP_003032339.1 253799338 8160644 2596127..2596714 1 NC_012943.1 hypothetical protein 2596714 8160644 TBMG_02370 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032339.1 2596127 D 478434 CDS YP_003032340.1 253799339 8160645 2596825..2598282 1 NC_012943.1 membrane cytochrome D ubiquinol oxidase subunit I cydA 2598282 8160645 TBMG_02371 Mycobacterium tuberculosis KZN 1435 membrane cytochrome D ubiquinol oxidase subunit I cydA YP_003032340.1 2596825 D 478434 CDS YP_003032341.1 253799340 8160646 2598312..2599352 1 NC_012943.1 membrane cytochrome D ubiquinol oxidase subunit II cydB 2599352 8160646 TBMG_02372 Mycobacterium tuberculosis KZN 1435 membrane cytochrome D ubiquinol oxidase subunit II cydB YP_003032341.1 2598312 D 478434 CDS YP_003032342.1 253799341 8160647 2599439..2601022 1 NC_012943.1 transmembrane ATP-binding protein ABC transporter cydD 2601022 8160647 TBMG_02373 Mycobacterium tuberculosis KZN 1435 transmembrane ATP-binding protein ABC transporter cydD YP_003032342.1 2599439 D 478434 CDS YP_003032343.1 253799342 8160648 2601019..2602749 1 NC_012943.1 transmembrane ATP-binding protein ABC transporter cydC 2602749 8160648 TBMG_02374 Mycobacterium tuberculosis KZN 1435 transmembrane ATP-binding protein ABC transporter cydC YP_003032343.1 2601019 D 478434 CDS YP_003032344.1 253799343 8160649 complement(2602683..2604137) 1 NC_012943.1 hypothetical protein 2604137 8160649 TBMG_02375 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032344.1 2602683 R 478434 CDS YP_003032345.1 253799344 8160650 complement(2604195..2605097) 1 NC_012943.1 acyl-CoA thioesterase 2605097 8160650 TBMG_02376 Mycobacterium tuberculosis KZN 1435 acyl-CoA thioesterase YP_003032345.1 2604195 R 478434 CDS YP_003032346.1 253799345 8160651 complement(2605105..2606523) 1 NC_012943.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2606523 8160651 TBMG_02377 Mycobacterium tuberculosis KZN 1435 pyruvate kinase YP_003032346.1 2605105 R 478434 CDS YP_003032347.1 253799346 8160652 complement(2606631..2607029) 1 NC_012943.1 hypothetical protein 2607029 8160652 TBMG_02378 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032347.1 2606631 R 478434 CDS YP_003032348.1 253799347 8160653 complement(2607019..2607459) 1 NC_012943.1 hypothetical protein 2607459 8160653 TBMG_02379 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032348.1 2607019 R 478434 CDS YP_003032349.1 253799348 8160654 complement(2608135..2609544) 1 NC_012943.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 2609544 8160654 TBMG_02380 Mycobacterium tuberculosis KZN 1435 prolipoprotein diacylglyceryl transferase YP_003032349.1 2608135 R 478434 CDS YP_003032350.1 253799349 8160655 complement(2609541..2610353) 1 NC_012943.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 2610353 trpA 8160655 trpA Mycobacterium tuberculosis KZN 1435 tryptophan synthase subunit alpha YP_003032350.1 2609541 R 478434 CDS YP_003032351.1 253799350 8160656 complement(2610353..2611621) 1 NC_012943.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2611621 8160656 TBMG_02382 Mycobacterium tuberculosis KZN 1435 tryptophan synthase subunit beta YP_003032351.1 2610353 R 478434 CDS YP_003032352.1 253799351 8160657 complement(2611654..2612502) 1 NC_012943.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 2612502 trpC 8160657 trpC Mycobacterium tuberculosis KZN 1435 indole-3-glycerol phosphate synthase YP_003032352.1 2611654 R 478434 CDS YP_003032353.1 253799352 8160658 complement(2612562..2613269) 1 NC_012943.1 hypothetical protein 2613269 8160658 TBMG_02384 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032353.1 2612562 R 478434 CDS YP_003032354.1 253799353 8160659 complement(2613259..2614809) 1 NC_012943.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 2614809 8160659 TBMG_02385 Mycobacterium tuberculosis KZN 1435 anthranilate synthase component I YP_003032354.1 2613259 R 478434 CDS YP_003032355.1 253799354 8160660 2614950..2615414 1 NC_012943.1 peroxidoxin bcpB 2615414 8160660 TBMG_02386 Mycobacterium tuberculosis KZN 1435 peroxidoxin bcpB YP_003032355.1 2614950 D 478434 CDS YP_003032356.1 253799355 8160661 complement(2615449..2616531) 1 NC_012943.1 hypothetical protein 2616531 8160661 TBMG_02387 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032356.1 2615449 R 478434 CDS YP_003032357.1 253799356 8160662 complement(2616712..2617059) 1 NC_012943.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 2617059 hisI 8160662 hisI Mycobacterium tuberculosis KZN 1435 phosphoribosyl-AMP cyclohydrolase YP_003032357.1 2616712 R 478434 CDS YP_003032358.1 253799357 8160663 complement(2617056..2617859) 1 NC_012943.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2617859 8160663 TBMG_02389 Mycobacterium tuberculosis KZN 1435 imidazole glycerol phosphate synthase subunit HisF YP_003032358.1 2617056 R 478434 CDS YP_003032359.1 253799358 8160664 complement(2617861..2618673) 1 NC_012943.1 inositol-monophosphatase impA 2618673 8160664 TBMG_02390 Mycobacterium tuberculosis KZN 1435 inositol-monophosphatase impA YP_003032359.1 2617861 R 478434 CDS YP_003032360.1 253799359 8160665 complement(2618681..2619418) 1 NC_012943.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A 2619418 8160665 TBMG_02391 Mycobacterium tuberculosis KZN 1435 phosphoribosyl isomerase A YP_003032360.1 2618681 R 478434 CDS YP_003032361.1 253799360 8160666 complement(2619428..2620048) 1 NC_012943.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2620048 hisH 8160666 hisH Mycobacterium tuberculosis KZN 1435 imidazole glycerol phosphate synthase subunit HisH YP_003032361.1 2619428 R 478434 CDS YP_003032362.1 253799361 8160667 complement(2620045..2620677) 1 NC_012943.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2620677 hisB 8160667 hisB Mycobacterium tuberculosis KZN 1435 imidazoleglycerol-phosphate dehydratase YP_003032362.1 2620045 R 478434 CDS YP_003032363.1 253799362 8160668 complement(2620674..2621816) 1 NC_012943.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2621816 8160668 TBMG_02394 Mycobacterium tuberculosis KZN 1435 histidinol-phosphate aminotransferase YP_003032363.1 2620674 R 478434 CDS YP_003032364.1 253799363 8160669 complement(2621813..2623156) 1 NC_012943.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2623156 hisD 8160669 hisD Mycobacterium tuberculosis KZN 1435 histidinol dehydrogenase YP_003032364.1 2621813 R 478434 CDS YP_003032365.1 253799364 8160670 2623229..2623639 1 NC_012943.1 hypothetical protein 2623639 8160670 TBMG_02396 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032365.1 2623229 D 478434 CDS YP_003032366.1 253799365 8160671 complement(2623660..2624418) 1 NC_012943.1 hypothetical protein 2624418 8160671 TBMG_02397 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032366.1 2623660 R 478434 CDS YP_003032367.1 253799366 8160672 complement(2624467..2625324) 1 NC_012943.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 2625324 8160672 TBMG_02398 Mycobacterium tuberculosis KZN 1435 nicotinate-nucleotide pyrophosphorylase YP_003032367.1 2624467 R 478434 CDS YP_003032368.1 253799367 8160673 complement(2625324..2626907) 1 NC_012943.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2626907 8160673 TBMG_02399 Mycobacterium tuberculosis KZN 1435 L-aspartate oxidase YP_003032368.1 2625324 R 478434 CDS YP_003032369.1 253799368 8160674 complement(2626907..2627956) 1 NC_012943.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 2627956 8160674 TBMG_02400 Mycobacterium tuberculosis KZN 1435 quinolinate synthetase YP_003032369.1 2626907 R 478434 CDS YP_003032370.1 253799369 8160675 2628005..2628715 1 NC_012943.1 hypothetical protein 2628715 8160675 TBMG_02401 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032370.1 2628005 D 478434 CDS YP_003032371.1 253799370 8160676 2628972..2630312 1 NC_012943.1 hypothetical protein 2630312 8160676 TBMG_02402 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032371.1 2628972 D 478434 CDS YP_003032372.1 253799371 8160677 complement(2630477..2631142) 1 NC_012943.1 hypothetical protein 2631142 8160677 TBMG_02403 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032372.1 2630477 R 478434 CDS YP_003032373.1 253799372 8160678 complement(2631379..2632428) 1 NC_012943.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase 2632428 8160678 TBMG_02404 Mycobacterium tuberculosis KZN 1435 biotin synthase YP_003032373.1 2631379 R 478434 CDS YP_003032374.1 253799373 8160679 2632876..2633544 1 NC_012943.1 hypothetical protein 2633544 8160679 TBMG_02405 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032374.1 2632876 D 478434 CDS YP_003032375.1 253799374 8160680 2633309..2634271 1 NC_012943.1 hypothetical protein 2634271 8160680 TBMG_02406 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032375.1 2633309 D 478434 CDS YP_003032376.1 253799375 8160681 complement(2634417..2634926) 1 NC_012943.1 hypothetical protein 2634926 8160681 TBMG_02407 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032376.1 2634417 R 478434 CDS YP_003032377.1 253799376 8160682 complement(2634926..2635606) 1 NC_012943.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 2635606 bioD 8160682 bioD Mycobacterium tuberculosis KZN 1435 dithiobiotin synthetase YP_003032377.1 2634926 R 478434 CDS YP_003032378.1 253799377 8160683 complement(2635603..2636763) 1 NC_012943.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 2636763 8160683 TBMG_02409 Mycobacterium tuberculosis KZN 1435 8-amino-7-oxononanoate synthase YP_003032378.1 2635603 R 478434 CDS YP_003032379.1 253799378 8160684 complement(2636760..2638073) 1 NC_012943.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2638073 8160684 TBMG_02410 Mycobacterium tuberculosis KZN 1435 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_003032379.1 2636760 R 478434 CDS YP_003032380.1 253799379 8160686 2638033..2638605 1 NC_012943.1 hypothetical protein 2638605 8160686 TBMG_02411 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032380.1 2638033 D 478434 CDS YP_003032381.1 253799380 8160685 2638788..2639537 1 NC_012943.1 invasion-associated protein 2639537 8160685 TBMG_02412 Mycobacterium tuberculosis KZN 1435 invasion-associated protein YP_003032381.1 2638788 D 478434 CDS YP_003032382.1 253799381 8160687 2639636..2641825 1 NC_012943.1 hypothetical protein 2641825 8160687 TBMG_02413 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032382.1 2639636 D 478434 CDS YP_003032383.1 253799382 8160688 2641864..2644029 1 NC_012943.1 maltooligosyltrehalose synthase treX 2644029 8160688 TBMG_02414 Mycobacterium tuberculosis KZN 1435 maltooligosyltrehalose synthase treX YP_003032383.1 2641864 D 478434 CDS YP_003032384.1 253799383 8160689 2644033..2646330 1 NC_012943.1 maltooligosyltrehalose synthase treY 2646330 8160689 TBMG_02415 Mycobacterium tuberculosis KZN 1435 maltooligosyltrehalose synthase treY YP_003032384.1 2644033 D 478434 CDS YP_003032385.1 253799384 8160690 2646323..2648065 1 NC_012943.1 maltooligosyltrehalose trehalohydrolase treZ 2648065 8160690 TBMG_02416 Mycobacterium tuberculosis KZN 1435 maltooligosyltrehalose trehalohydrolase treZ YP_003032385.1 2646323 D 478434 CDS YP_003032386.1 253799385 8160691 complement(2648082..2648486) 1 NC_012943.1 toxin 2648486 8160691 TBMG_02417 Mycobacterium tuberculosis KZN 1435 toxin YP_003032386.1 2648082 R 478434 CDS YP_003032387.1 253799386 8160692 complement(2648492..2648710) 1 NC_012943.1 antitoxin 2648710 8160692 TBMG_02418 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032387.1 2648492 R 478434 CDS YP_003032388.1 253799387 8160693 complement(2648748..2650037) 1 NC_012943.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 2650037 8160693 TBMG_02419 Mycobacterium tuberculosis KZN 1435 threonine dehydratase YP_003032388.1 2648748 R 478434 CDS YP_003032389.1 253799388 8160694 complement(2650072..2650518) 1 NC_012943.1 hypothetical protein 2650518 8160694 TBMG_02420 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032389.1 2650072 R 478434 CDS YP_003032390.1 253799389 8160695 complement(2650528..2651721) 1 NC_012943.1 transmembrane transporter mmpL6 2651721 8160695 TBMG_02421 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL6 YP_003032390.1 2650528 R 478434 CDS YP_003032391.1 253799390 8160696 complement(2651860..2652468) 1 NC_012943.1 regulatory protein 2652468 8160696 TBMG_02422 Mycobacterium tuberculosis KZN 1435 regulatory protein YP_003032391.1 2651860 R 478434 CDS YP_003032392.1 253799391 8160697 complement(2652536..2652913) 1 NC_012943.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 2652913 8160697 TBMG_02423 Mycobacterium tuberculosis KZN 1435 fumarate reductase subunit D YP_003032392.1 2652536 R 478434 CDS YP_003032393.1 253799392 8160698 complement(2652910..2653290) 1 NC_012943.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 2653290 8160698 TBMG_02424 Mycobacterium tuberculosis KZN 1435 fumarate reductase subunit C YP_003032393.1 2652910 R 478434 CDS YP_003032394.1 253799393 8160699 complement(2653287..2654030) 1 NC_012943.1 fumarate reductase iron-sulfur subunit frdB 2654030 8160699 TBMG_02425 Mycobacterium tuberculosis KZN 1435 fumarate reductase iron-sulfur subunit frdB YP_003032394.1 2653287 R 478434 CDS YP_003032395.1 253799394 8160700 complement(2654033..2655784) 1 NC_012943.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 2655784 8160700 TBMG_02426 Mycobacterium tuberculosis KZN 1435 fumarate reductase flavoprotein subunit YP_003032395.1 2654033 R 478434 CDS YP_003032396.1 253799395 8160701 complement(2656155..2658020) 1 NC_012943.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 2658020 8160701 TBMG_02427 Mycobacterium tuberculosis KZN 1435 glycerol-3-phosphate acyltransferase YP_003032396.1 2656155 R 478434 CDS YP_003032397.1 253799396 8160702 complement(2658034..2659749) 1 NC_012943.1 fatty-acid-CoA ligase fadD11 2659749 8160702 TBMG_02428 Mycobacterium tuberculosis KZN 1435 fatty-acid-CoA ligase fadD11 YP_003032397.1 2658034 R 478434 CDS YP_003032398.1 253799397 8160703 2660133..2662169 1 NC_012943.1 PPE family protein 2662169 8160703 TBMG_02429 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032398.1 2660133 D 478434 CDS YP_003032399.1 253799398 8160704 complement(2662218..2665772) 1 NC_012943.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 2665772 dnaE 8160704 dnaE Mycobacterium tuberculosis KZN 1435 DNA polymerase III subunit alpha YP_003032399.1 2662218 R 478434 CDS YP_003032400.1 253799399 8160705 complement(2665840..2666271) 1 NC_012943.1 hypothetical protein 2666271 8160705 TBMG_02431 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032400.1 2665840 R 478434 CDS YP_003032401.1 253799400 8160706 complement(2666320..2666547) 1 NC_012943.1 hypothetical protein 2666547 8160706 TBMG_02432 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032401.1 2666320 R 478434 CDS YP_003032402.1 253799401 8160707 complement(2666569..2667372) 1 NC_012943.1 ketoacyl reductase 2667372 8160707 TBMG_02433 Mycobacterium tuberculosis KZN 1435 ketoacyl reductase YP_003032402.1 2666569 R 478434 CDS YP_003032403.1 253799402 8160708 complement(2667377..2668402) 1 NC_012943.1 fatty-acyl-CoA reductase 2668402 8160708 TBMG_02434 Mycobacterium tuberculosis KZN 1435 fatty-acyl-CoA reductase YP_003032403.1 2667377 R 478434 CDS YP_003032404.1 253799403 8160709 2668630..2669040 1 NC_012943.1 hemoglobin glbN 2669040 8160709 TBMG_02435 Mycobacterium tuberculosis KZN 1435 hemoglobin glbN YP_003032404.1 2668630 D 478434 CDS YP_003032405.1 253799404 8160710 2669095..2669688 1 NC_012943.1 hypothetical protein 2669688 8160710 TBMG_02436 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032405.1 2669095 D 478434 CDS YP_003032406.1 253799405 8160711 complement(2669695..2670621) 1 NC_012943.1 hypothetical protein 2670621 8160711 TBMG_02437 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032406.1 2669695 R 478434 CDS YP_003032407.1 253799406 8160712 complement(2670614..2671288) 1 NC_012943.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 2671288 8160712 TBMG_02438 Mycobacterium tuberculosis KZN 1435 lipoprotein signal peptidase YP_003032407.1 2670614 R 478434 CDS YP_003032408.1 253799407 8160714 2671274..2672254 1 NC_012943.1 L-aparaginase ansA 2672254 8160714 TBMG_02439 Mycobacterium tuberculosis KZN 1435 L-aparaginase ansA YP_003032408.1 2671274 D 478434 CDS YP_003032409.1 253799408 8160713 complement(2672219..2673625) 1 NC_012943.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2673625 8160713 TBMG_02440 Mycobacterium tuberculosis KZN 1435 DNA polymerase IV YP_003032409.1 2672219 R 478434 CDS YP_003032410.1 253799409 8160715 complement(2673822..2676947) 1 NC_012943.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 2676947 ileS 8160715 ileS Mycobacterium tuberculosis KZN 1435 isoleucyl-tRNA synthetase YP_003032410.1 2673822 R 478434 CDS YP_003032411.1 253799410 8160716 complement(2677254..2677490) 1 NC_012943.1 hypothetical protein 2677490 8160716 TBMG_02442 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032411.1 2677254 R 478434 CDS YP_003032412.1 253799411 8160717 complement(2678055..2678732) 1 NC_012943.1 transcriptional regulator 2678732 8160717 TBMG_02443 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032412.1 2678055 R 478434 CDS YP_003032413.1 253799412 8160718 complement(2678729..2679856) 1 NC_012943.1 hypothetical protein 2679856 8160718 TBMG_02444 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032413.1 2678729 R 478434 CDS YP_003032414.1 253799413 8160719 2679916..2680350 1 NC_012943.1 hypothetical protein 2680350 8160719 TBMG_02445 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032414.1 2679916 D 478434 CDS YP_003032415.1 253799414 8160720 complement(2680427..2680993) 1 NC_012943.1 hypothetical protein 2680993 8160720 TBMG_02446 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032415.1 2680427 R 478434 CDS YP_003032416.1 253799415 8160721 complement(2680990..2682093) 1 NC_012943.1 alcohol dehydrogenase 2682093 8160721 TBMG_02447 Mycobacterium tuberculosis KZN 1435 alcohol dehydrogenase YP_003032416.1 2680990 R 478434 CDS YP_003032417.1 253799416 8160722 complement(2682210..2683964) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2683964 8160722 TBMG_02448 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003032417.1 2682210 R 478434 CDS YP_003032418.1 253799417 8160723 2684016..2684513 1 NC_012943.1 polyketide synthase 2684513 8160723 TBMG_02449 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003032418.1 2684016 D 478434 CDS YP_003032419.1 253799418 8160724 2685057..2691383 1 NC_012943.1 polyketide synthase 2691383 8160724 TBMG_02450 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003032419.1 2685057 D 478434 CDS YP_003032420.1 253799419 8160725 2691406..2692686 1 NC_012943.1 glycosyltransferase 2692686 8160725 TBMG_02451 Mycobacterium tuberculosis KZN 1435 glycosyltransferase YP_003032420.1 2691406 D 478434 CDS YP_003032421.1 253799420 8160726 complement(2692664..2693449) 1 NC_012943.1 rhamnosyl transferase wbbL2 2693449 8160726 TBMG_02452 Mycobacterium tuberculosis KZN 1435 rhamnosyl transferase wbbL2 YP_003032421.1 2692664 R 478434 CDS YP_003032422.1 253799421 8160727 complement(2693496..2694740) 1 NC_012943.1 glycosyltransferase 2694740 8160727 TBMG_02453 Mycobacterium tuberculosis KZN 1435 glycosyltransferase YP_003032422.1 2693496 R 478434 CDS YP_003032423.1 253799422 8160728 complement(2694770..2695813) 1 NC_012943.1 methyltransferase 2695813 8160728 TBMG_02454 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032423.1 2694770 R 478434 CDS YP_003032424.1 253799423 8160730 2695758..2699294 1 NC_012943.1 transmembrane transporter mmpL12 2699294 8160730 TBMG_02455 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL12 YP_003032424.1 2695758 D 478434 CDS YP_003032425.1 253799424 8160729 complement(2699413..2701164) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2701164 8160729 TBMG_02456 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003032425.1 2699413 R 478434 CDS YP_003032426.1 253799425 8160731 complement(2701398..2702471) 1 NC_012943.1 sugar transferase 2702471 8160731 TBMG_02457 Mycobacterium tuberculosis KZN 1435 sugar transferase YP_003032426.1 2701398 R 478434 CDS YP_003032427.1 253799426 8160732 complement(2702863..2703822) 1 NC_012943.1 hypothetical protein 2703822 8160732 TBMG_02458 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032427.1 2702863 R 478434 CDS YP_003032428.1 253799427 8160733 complement(2703831..2704595) 1 NC_012943.1 hypothetical protein 2704595 8160733 TBMG_02459 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032428.1 2703831 R 478434 CDS YP_003032429.1 253799428 8160734 2704927..2705937 1 NC_012943.1 sugar transferase 2705937 8160734 TBMG_02460 Mycobacterium tuberculosis KZN 1435 sugar transferase YP_003032429.1 2704927 D 478434 CDS YP_003032430.1 253799429 8160735 2705940..2706836 1 NC_012943.1 hypothetical protein 2706836 8160735 TBMG_02461 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032430.1 2705940 D 478434 CDS YP_003032431.1 253799430 8160736 2706871..2707659 1 NC_012943.1 hypothetical protein 2707659 8160736 TBMG_02462 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032431.1 2706871 D 478434 CDS YP_003032432.1 253799431 8160737 complement(2707677..2708408) 1 NC_012943.1 hypothetical protein 2708408 8160737 TBMG_02463 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032432.1 2707677 R 478434 CDS YP_003032433.1 253799432 8160738 complement(2708405..2709373) 1 NC_012943.1 nucleotide-sugar epimerase epiA 2709373 8160738 TBMG_02464 Mycobacterium tuberculosis KZN 1435 nucleotide-sugar epimerase epiA YP_003032433.1 2708405 R 478434 CDS YP_003032434.1 253799433 8160739 complement(2709370..2710416) 1 NC_012943.1 GDP-D-mannose dehydratase gmdA 2710416 8160739 TBMG_02465 Mycobacterium tuberculosis KZN 1435 GDP-D-mannose dehydratase gmdA YP_003032434.1 2709370 R 478434 CDS YP_003032435.1 253799434 8160740 complement(2710450..2710869) 1 NC_012943.1 hypothetical protein 2710869 8160740 TBMG_02466 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032435.1 2710450 R 478434 CDS YP_003032436.1 253799435 8164493 complement(2710873..2712171) 1 NC_012943.1 hypothetical protein 2712171 8164493 TBMG_02467 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032436.1 2710873 R 478434 CDS YP_003032437.1 253799436 8160825 complement(2712373..2713254) 1 NC_012943.1 hypothetical protein 2713254 8160825 TBMG_02468 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032437.1 2712373 R 478434 CDS YP_003032438.1 253799437 8160826 complement(2713238..2713600) 1 NC_012943.1 hypothetical protein 2713600 8160826 TBMG_02469 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032438.1 2713238 R 478434 CDS YP_003032439.1 253799438 8160828 2713572..2715371 1 NC_012943.1 hypothetical protein 2715371 8160828 TBMG_02470 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032439.1 2713572 D 478434 CDS YP_003032440.1 253799439 8160827 complement(2715607..2716110) 1 NC_012943.1 hypothetical protein 2716110 8160827 TBMG_02471 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032440.1 2715607 R 478434 CDS YP_003032441.1 253799440 8160830 2716044..2716739 1 NC_012943.1 hypothetical protein 2716739 8160830 TBMG_02472 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032441.1 2716044 D 478434 CDS YP_003032442.1 253799441 8160829 2717023..2717523 1 NC_012943.1 hypothetical protein 2717523 8160829 TBMG_02473 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032442.1 2717023 D 478434 CDS YP_003032443.1 253799442 8160831 2717520..2718185 1 NC_012943.1 hypothetical protein 2718185 8160831 TBMG_02474 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032443.1 2717520 D 478434 CDS YP_003032444.1 253799443 8160832 2718322..2718921 1 NC_012943.1 hypothetical protein 2718921 8160832 TBMG_02475 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032444.1 2718322 D 478434 CDS YP_003032445.1 253799444 8160833 2718928..2719470 1 NC_012943.1 hypothetical protein 2719470 8160833 TBMG_02476 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032445.1 2718928 D 478434 CDS YP_003032446.1 253799445 8160834 complement(2719643..2720542) 1 NC_012943.1 hypothetical protein 2720542 8160834 TBMG_02477 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032446.1 2719643 R 478434 CDS YP_003032447.1 253799446 8160835 complement(2720755..2721576) 1 NC_012943.1 hypothetical protein 2721576 8160835 TBMG_02478 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032447.1 2720755 R 478434 CDS YP_003032448.1 253799447 8160836 complement(2721588..2722616) 1 NC_012943.1 glycosyltransferase 2722616 8160836 TBMG_02479 Mycobacterium tuberculosis KZN 1435 glycosyltransferase YP_003032448.1 2721588 R 478434 CDS YP_003032449.1 253799448 8160837 complement(2722661..2723059) 1 NC_012943.1 hypothetical protein 2723059 8160837 TBMG_02480 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032449.1 2722661 R 478434 CDS YP_003032450.1 253799449 8160838 2723120..2723332 1 NC_012943.1 hypothetical protein 2723332 8160838 TBMG_02481 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032450.1 2723120 D 478434 CDS YP_003032451.1 253799450 8160839 2723546..2724163 1 NC_012943.1 methyltransferase 2724163 8160839 TBMG_02482 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032451.1 2723546 D 478434 CDS YP_003032452.1 253799451 8160840 complement(2724236..2725525) 1 NC_012943.1 esterase lipL 2725525 8160840 TBMG_02483 Mycobacterium tuberculosis KZN 1435 esterase lipL YP_003032452.1 2724236 R 478434 CDS YP_003032453.1 253799452 8160841 complement(2725578..2726582) 1 NC_012943.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 2726582 8160841 TBMG_02484 Mycobacterium tuberculosis KZN 1435 arginine/ornithine transport system ATPase YP_003032453.1 2725578 R 478434 CDS YP_003032454.1 253799453 8160842 complement(2726579..2726896) 1 NC_012943.1 toxin 2726896 8160842 TBMG_02485 Mycobacterium tuberculosis KZN 1435 toxin YP_003032454.1 2726579 R 478434 CDS YP_003032455.1 253799454 8160843 complement(2726893..2727195) 1 NC_012943.1 antitoxin 2727195 8160843 TBMG_02486 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032455.1 2726893 R 478434 CDS YP_003032456.1 253799455 8160844 complement(2727209..2729461) 1 NC_012943.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 2729461 8160844 TBMG_02487 Mycobacterium tuberculosis KZN 1435 methylmalonyl-CoA mutase YP_003032456.1 2727209 R 478434 CDS YP_003032457.1 253799456 8160845 complement(2729462..2731333) 1 NC_012943.1 methylmalonyl-CoA mutase small subunit mutA 2731333 8160845 TBMG_02488 Mycobacterium tuberculosis KZN 1435 methylmalonyl-CoA mutase small subunit mutA YP_003032457.1 2729462 R 478434 CDS YP_003032458.1 253799457 8160846 2731500..2732258 1 NC_012943.1 hypothetical protein 2732258 8160846 TBMG_02489 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032458.1 2731500 D 478434 CDS YP_003032459.1 253799458 8160847 complement(2732476..2732739) 1 NC_012943.1 hypothetical protein 2732739 8160847 TBMG_04062 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032459.1 2732476 R 478434 CDS YP_003032460.1 253799459 8160848 complement(2732837..2734144) 1 NC_012943.1 hypothetical protein 2734144 8160848 TBMG_02490 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032460.1 2732837 R 478434 CDS YP_003032461.1 253799460 8160849 complement(2734294..2734524) 1 NC_012943.1 hypothetical protein 2734524 8160849 TBMG_02491 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032461.1 2734294 R 478434 CDS YP_003032462.1 253799461 8160850 complement(2734558..2734914) 1 NC_012943.1 hypothetical protein 2734914 8160850 TBMG_02492 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032462.1 2734558 R 478434 CDS YP_003032463.1 253799462 8160851 complement(2734924..2736069) 1 NC_012943.1 hypothetical protein 2736069 8160851 TBMG_02493 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032463.1 2734924 R 478434 CDS YP_003032464.1 253799463 8160852 complement(2736091..2736525) 1 NC_012943.1 hypothetical protein 2736525 8160852 TBMG_02494 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032464.1 2736091 R 478434 CDS YP_003032465.1 253799464 8160853 2736541..2737449 1 NC_012943.1 hypothetical protein 2737449 8160853 TBMG_02495 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032465.1 2736541 D 478434 CDS YP_003032466.1 253799465 8160854 complement(2737415..2738449) 1 NC_012943.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 2738449 hemH 8160854 hemH Mycobacterium tuberculosis KZN 1435 ferrochelatase YP_003032466.1 2737415 R 478434 CDS YP_003032467.1 253799466 8160855 complement(2738455..2739264) 1 NC_012943.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 2739264 8160855 TBMG_02497 Mycobacterium tuberculosis KZN 1435 enoyl-(acyl carrier protein) reductase YP_003032467.1 2738455 R 478434 CDS YP_003032468.1 253799467 8160856 complement(2739283..2740026) 1 NC_012943.1 3-oxoacyl-ACP reductase 2740026 8160856 TBMG_02498 Mycobacterium tuberculosis KZN 1435 3-oxoacyl-ACP reductase YP_003032468.1 2739283 R 478434 CDS YP_003032469.1 253799468 8160857 2740167..2741009 1 NC_012943.1 hypothetical protein 2741009 8160857 TBMG_02499 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032469.1 2740167 D 478434 CDS YP_003032470.1 253799469 8160858 complement(2741082..2742089) 1 NC_012943.1 hypothetical protein 2742089 8160858 TBMG_02500 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032470.1 2741082 R 478434 CDS YP_003032471.1 253799470 8160859 complement(2742100..2743053) 1 NC_012943.1 hypothetical protein 2743053 8160859 TBMG_02501 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032471.1 2742100 R 478434 CDS YP_003032472.1 253799471 8160860 complement(2743050..2744183) 1 NC_012943.1 transcriptional regulator moxR1 2744183 8160860 TBMG_02502 Mycobacterium tuberculosis KZN 1435 transcriptional regulator moxR1 YP_003032472.1 2743050 R 478434 CDS YP_003032473.1 253799472 8160861 complement(2744322..2745083) 1 NC_012943.1 invasion-associated protein 2745083 8160861 TBMG_02503 Mycobacterium tuberculosis KZN 1435 invasion-associated protein YP_003032473.1 2744322 R 478434 CDS YP_003032474.1 253799473 8160862 complement(2745058..2746476) 1 NC_012943.1 invasion-associated protein 2746476 8160862 TBMG_02504 Mycobacterium tuberculosis KZN 1435 invasion-associated protein YP_003032474.1 2745058 R 478434 CDS YP_003032475.1 253799474 8160863 complement(2746702..2747262) 1 NC_012943.1 hypothetical protein 2747262 8160863 TBMG_02505 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032475.1 2746702 R 478434 CDS YP_003032476.1 253799475 8160864 2747420..2750251 1 NC_012943.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 2750251 8160864 TBMG_02506 Mycobacterium tuberculosis KZN 1435 aconitate hydratase YP_003032476.1 2747420 D 478434 CDS YP_003032477.1 253799476 8160865 2750262..2750825 1 NC_012943.1 transcriptional regulator 2750825 8160865 TBMG_02507 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032477.1 2750262 D 478434 CDS YP_003032478.1 253799477 8160866 complement(2750894..2751085) 1 NC_012943.1 transcriptional regulator 2751085 8160866 TBMG_02508 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032478.1 2750894 R 478434 CDS YP_003032479.1 253799478 8160867 complement(2751182..2752810) 1 NC_012943.1 macrolide-transport ATP-binding protein ABC transporter 2752810 8160867 TBMG_02509 Mycobacterium tuberculosis KZN 1435 macrolide-transport ATP-binding protein ABC transporter YP_003032479.1 2751182 R 478434 CDS YP_003032480.1 253799479 8160868 complement(2752846..2753703) 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2753703 8160868 TBMG_02510 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003032480.1 2752846 R 478434 CDS YP_003032481.1 253799480 8160869 complement(2753725..2754096) 1 NC_012943.1 thioredoxin trxB1 2754096 8160869 TBMG_02511 Mycobacterium tuberculosis KZN 1435 thioredoxin trxB1 YP_003032481.1 2753725 R 478434 CDS YP_003032482.1 253799481 8160870 complement(2754112..2754486) 1 NC_012943.1 thioredoxin trxA 2754486 8160870 TBMG_02512 Mycobacterium tuberculosis KZN 1435 thioredoxin trxA YP_003032482.1 2754112 R 478434 CDS YP_003032483.1 253799482 8160871 complement(2754530..2756503) 1 NC_012943.1 cation transporter P-type ATPase D ctpD 2756503 8160871 TBMG_02513 Mycobacterium tuberculosis KZN 1435 cation transporter P-type ATPase D ctpD YP_003032483.1 2754530 R 478434 CDS YP_003032484.1 253799483 8160872 2756730..2757857 1 NC_012943.1 PE-PGRS family protein 2757857 8160872 TBMG_02514 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032484.1 2756730 D 478434 CDS YP_003032485.1 253799484 8160873 2757964..2759793 1 NC_012943.1 acyl-CoA dehydrogenase 2759793 8160873 TBMG_02515 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003032485.1 2757964 D 478434 CDS YP_003032486.1 253799485 8160874 complement(2759888..2760235) 1 NC_012943.1 hypothetical protein 2760235 8160874 TBMG_02516 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032486.1 2759888 R 478434 CDS YP_003032487.1 253799486 8160875 complement(2760210..2760698) 1 NC_012943.1 nitrogen fixation related protein 2760698 8160875 TBMG_02517 Mycobacterium tuberculosis KZN 1435 nitrogen fixation related protein YP_003032487.1 2760210 R 478434 CDS YP_003032488.1 253799487 8160876 complement(2760695..2761948) 1 NC_012943.1 cysteine desulfurase csd 2761948 8160876 TBMG_02518 Mycobacterium tuberculosis KZN 1435 cysteine desulfurase csd YP_003032488.1 2760695 R 478434 CDS YP_003032489.1 253799488 8160877 complement(2761950..2762750) 1 NC_012943.1 ABC transporter ATP-binding protein 2762750 8160877 TBMG_02519 Mycobacterium tuberculosis KZN 1435 ABC transporter ATP-binding protein YP_003032489.1 2761950 R 478434 CDS YP_003032490.1 253799489 8160878 complement(2762747..2763940) 1 NC_012943.1 FeS assembly protein SufD 2763940 8160878 TBMG_02520 Mycobacterium tuberculosis KZN 1435 FeS assembly protein SufD YP_003032490.1 2762747 R 478434 CDS YP_003032491.1 253799490 8160879 complement(2763937..2766477) 1 NC_012943.1 hypothetical protein 2766477 8160879 TBMG_02521 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032491.1 2763937 R 478434 CDS YP_003032492.1 253799491 8160880 complement(2766474..2767280) 1 NC_012943.1 transcriptional regulator 2767280 8160880 TBMG_02522 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032492.1 2766474 R 478434 CDS YP_003032493.1 253799492 8160881 2767328..2769103 1 NC_012943.1 hypothetical protein 2769103 8160881 TBMG_02523 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032493.1 2767328 D 478434 CDS YP_003032494.1 253799493 8160882 2769259..2770200 1 NC_012943.1 antibiotic-transport ATP-binding protein ABC transporter 2770200 8160882 TBMG_02524 Mycobacterium tuberculosis KZN 1435 antibiotic-transport ATP-binding protein ABC transporter YP_003032494.1 2769259 D 478434 CDS YP_003032495.1 253799494 8160883 2770197..2770982 1 NC_012943.1 antibiotic-transport membrane ABC transporter 2770982 8160883 TBMG_02525 Mycobacterium tuberculosis KZN 1435 antibiotic-transport membrane ABC transporter YP_003032495.1 2770197 D 478434 CDS YP_003032496.1 253799495 8160884 2771094..2772026 1 NC_012943.1 antibiotic-transport membrane ABC transporter 2772026 8160884 TBMG_02526 Mycobacterium tuberculosis KZN 1435 antibiotic-transport membrane ABC transporter YP_003032496.1 2771094 D 478434 CDS YP_003032497.1 253799496 8160885 complement(2771976..2772839) 1 NC_012943.1 hypothetical protein 2772839 8160885 TBMG_02527 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032497.1 2771976 R 478434 CDS YP_003032498.1 253799497 8160887 2772838..2773845 1 NC_012943.1 quinone reductase qor 2773845 8160887 TBMG_02528 Mycobacterium tuberculosis KZN 1435 quinone reductase qor YP_003032498.1 2772838 D 478434 CDS YP_003032499.1 253799498 8160886 complement(2773873..2775171) 1 NC_012943.1 transcriptional activator 2775171 8160886 TBMG_02529 Mycobacterium tuberculosis KZN 1435 transcriptional activator YP_003032499.1 2773873 R 478434 CDS YP_003032500.1 253799499 8160888 2775287..2777503 1 NC_012943.1 PE-PGRS family protein 2777503 8160888 TBMG_02530 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032500.1 2775287 D 478434 CDS YP_003032501.1 253799500 8160889 complement(2777552..2778478) 1 NC_012943.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 2778478 8160889 TBMG_04063 Mycobacterium tuberculosis KZN 1435 protoheme IX farnesyltransferase YP_003032501.1 2777552 R 478434 CDS YP_003032502.1 253799501 8160890 2778877..2783103 1 NC_012943.1 hypothetical protein 2783103 8160890 TBMG_02531 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032502.1 2778877 D 478434 CDS YP_003032503.1 253799502 8160891 2783542..2785644 1 NC_012943.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2785644 8160891 TBMG_02532 Mycobacterium tuberculosis KZN 1435 transketolase YP_003032503.1 2783542 D 478434 CDS YP_003032504.1 253799503 8160892 2785661..2786782 1 NC_012943.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 2786782 8160892 TBMG_02533 Mycobacterium tuberculosis KZN 1435 transaldolase YP_003032504.1 2785661 D 478434 CDS YP_003032505.1 253799504 8160893 2786779..2788323 1 NC_012943.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2788323 8160893 TBMG_02534 Mycobacterium tuberculosis KZN 1435 glucose-6-phosphate 1-dehydrogenase YP_003032505.1 2786779 D 478434 CDS YP_003032506.1 253799505 8160894 2788376..2789287 1 NC_012943.1 oxpp cycle protein opcA 2789287 8160894 TBMG_02535 Mycobacterium tuberculosis KZN 1435 oxpp cycle protein opcA YP_003032506.1 2788376 D 478434 CDS YP_003032507.1 253799506 8160895 2789284..2790027 1 NC_012943.1 6-phosphogluconolactonase 2790027 8160895 TBMG_02536 Mycobacterium tuberculosis KZN 1435 6-phosphogluconolactonase YP_003032507.1 2789284 D 478434 CDS YP_003032508.1 253799507 8160896 2790044..2790454 1 NC_012943.1 hypothetical protein 2790454 8160896 TBMG_02537 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032508.1 2790044 D 478434 CDS YP_003032509.1 253799508 8160897 2791049..2791534 1 NC_012943.1 hypothetical protein 2791534 8160897 TBMG_02538 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032509.1 2791049 D 478434 CDS YP_003032510.1 253799509 8160898 complement(2791650..2793950) 1 NC_012943.1 biotin sulfoxide reductase bisC 2793950 8160898 TBMG_02539 Mycobacterium tuberculosis KZN 1435 biotin sulfoxide reductase bisC YP_003032510.1 2791650 R 478434 CDS YP_003032511.1 253799510 8160899 2794057..2795475 1 NC_012943.1 PE-PGRS family protein 2795475 8160899 TBMG_02540 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032511.1 2794057 D 478434 CDS YP_003032512.1 253799511 8160900 complement(2795614..2796027) 1 NC_012943.1 hypothetical protein 2796027 8160900 TBMG_02541 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032512.1 2795614 R 478434 CDS YP_003032513.1 253799512 8160901 2796298..2796723 1 NC_012943.1 hypothetical protein 2796723 8160901 TBMG_02542 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032513.1 2796298 D 478434 CDS YP_003032514.1 253799513 8160902 complement(2797335..2798120) 1 NC_012943.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 2798120 tpiA 8160902 tpiA Mycobacterium tuberculosis KZN 1435 triosephosphate isomerase YP_003032514.1 2797335 R 478434 CDS YP_003032515.1 253799514 8160903 complement(2798117..2799355) 1 NC_012943.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 2799355 pgk 8160903 pgk Mycobacterium tuberculosis KZN 1435 phosphoglycerate kinase YP_003032515.1 2798117 R 478434 CDS YP_003032516.1 253799515 8160904 complement(2799358..2800377) 1 NC_012943.1 glyceraldehyde-3-phosphate dehydrogenase 2800377 8160904 TBMG_02546 Mycobacterium tuberculosis KZN 1435 glyceraldehyde-3-phosphate dehydrogenase YP_003032516.1 2799358 R 478434 CDS YP_003032517.1 253799516 8160905 2800743..2801363 1 NC_012943.1 hypothetical protein 2801363 8160905 TBMG_02547 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032517.1 2800743 D 478434 CDS YP_003032518.1 253799517 8160906 complement(2801456..2802271) 1 NC_012943.1 hypothetical protein 2802271 8160906 TBMG_02548 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032518.1 2801456 R 478434 CDS YP_003032519.1 253799518 8160907 complement(2802435..2803856) 1 NC_012943.1 dehydrogenase 2803856 8160907 TBMG_04064 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003032519.1 2802435 R 478434 CDS YP_003032520.1 253799519 8160908 complement(2803853..2805622) 1 NC_012943.1 hypothetical protein 2805622 8160908 TBMG_02549 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032520.1 2803853 R 478434 CDS YP_003032521.1 253799520 8160909 complement(2805733..2807319) 1 NC_012943.1 PE family protein 2807319 8160909 TBMG_02550 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032521.1 2805733 R 478434 CDS YP_003032522.1 253799521 8160910 complement(2807559..2808827) 1 NC_012943.1 hypothetical protein 2808827 8160910 TBMG_02551 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032522.1 2807559 R 478434 CDS YP_003032523.1 253799522 8160911 2808946..2809773 1 NC_012943.1 hypothetical protein 2809773 8160911 TBMG_02552 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032523.1 2808946 D 478434 CDS YP_003032524.1 253799523 8160912 2809777..2811384 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2811384 8160912 TBMG_02553 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003032524.1 2809777 D 478434 CDS YP_003032525.1 253799524 8160913 2811384..2812646 1 NC_012943.1 esterase lipO 2812646 8160913 TBMG_02554 Mycobacterium tuberculosis KZN 1435 esterase lipO YP_003032525.1 2811384 D 478434 CDS YP_003032526.1 253799525 8160914 complement(2812668..2814047) 1 NC_012943.1 hypothetical protein 2814047 8160914 TBMG_02555 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032526.1 2812668 R 478434 CDS YP_003032527.1 253799526 8160915 2814051..2814812 1 NC_012943.1 hypothetical protein 2814812 8160915 TBMG_02556 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032527.1 2814051 D 478434 CDS YP_003032528.1 253799527 8160916 complement(2814822..2815805) 1 NC_012943.1 hypothetical protein 2815805 8160916 TBMG_02557 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032528.1 2814822 R 478434 CDS YP_003032529.1 253799528 8160917 complement(2815796..2816824) 1 NC_012943.1 hypothetical protein 2816824 8160917 TBMG_02558 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032529.1 2815796 R 478434 CDS YP_003032530.1 253799529 8160918 complement(2816821..2817726) 1 NC_012943.1 hypothetical protein 2817726 8160918 TBMG_02559 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032530.1 2816821 R 478434 CDS YP_003032531.1 253799530 8160919 complement(2817723..2819663) 1 NC_012943.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2819663 uvrC 8160919 uvrC Mycobacterium tuberculosis KZN 1435 excinuclease ABC subunit C YP_003032531.1 2817723 R 478434 CDS YP_003032532.1 253799531 8160920 complement(2819727..2820200) 1 NC_012943.1 hypothetical protein 2820200 8160920 TBMG_02561 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032532.1 2819727 R 478434 CDS YP_003032533.1 253799532 8160921 complement(2820380..2821066) 1 NC_012943.1 hypothetical protein 2821066 8160921 TBMG_02562 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032533.1 2820380 R 478434 CDS YP_003032534.1 253799533 8160922 complement(2821091..2821555) 1 NC_012943.1 hypothetical protein 2821555 8160922 TBMG_02563 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032534.1 2821091 R 478434 CDS YP_003032535.1 253799534 8160923 complement(2821552..2822034) 1 NC_012943.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 2822034 ribH 8160923 ribH Mycobacterium tuberculosis KZN 1435 6,7-dimethyl-8-ribityllumazine synthase YP_003032535.1 2821552 R 478434 CDS YP_003032536.1 253799535 8160924 complement(2822031..2823308) 1 NC_012943.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 2823308 8160924 TBMG_02565 Mycobacterium tuberculosis KZN 1435 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein YP_003032536.1 2822031 R 478434 CDS YP_003032537.1 253799536 8160925 complement(2823413..2823814) 1 NC_012943.1 hypothetical protein 2823814 8160925 TBMG_02566 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032537.1 2823413 R 478434 CDS YP_003032538.1 253799537 8160926 complement(2823804..2824319) 1 NC_012943.1 hypothetical protein 2824319 8160926 TBMG_02567 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032538.1 2823804 R 478434 CDS YP_003032539.1 253799538 8160927 complement(2824533..2825138) 1 NC_012943.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 2825138 8160927 TBMG_02568 Mycobacterium tuberculosis KZN 1435 riboflavin synthase subunit alpha YP_003032539.1 2824533 R 478434 CDS YP_003032540.1 253799539 8160928 2825214..2825933 1 NC_012943.1 hypothetical protein 2825933 8160928 TBMG_02569 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032540.1 2825214 D 478434 CDS YP_003032541.1 253799540 8160929 2825939..2827495 1 NC_012943.1 hypothetical protein 2827495 8160929 TBMG_02570 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032541.1 2825939 D 478434 CDS YP_003032542.1 253799541 8160930 complement(2827492..2828511) 1 NC_012943.1 riboflavin biosynthesis protein ribG 2828511 8160930 TBMG_02571 Mycobacterium tuberculosis KZN 1435 riboflavin biosynthesis protein ribG YP_003032542.1 2827492 R 478434 CDS YP_003032543.1 253799542 8160931 complement(2828508..2829206) 1 NC_012943.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 2829206 8160931 TBMG_02572 Mycobacterium tuberculosis KZN 1435 ribulose-phosphate 3-epimerase YP_003032543.1 2828508 R 478434 CDS YP_003032544.1 253799543 8160932 complement(2829231..2830604) 1 NC_012943.1 SUN protein 2830604 8160932 TBMG_02573 Mycobacterium tuberculosis KZN 1435 SUN protein YP_003032544.1 2829231 R 478434 CDS YP_003032545.1 253799544 8160933 complement(2830601..2831539) 1 NC_012943.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 2831539 fmt 8160933 fmt Mycobacterium tuberculosis KZN 1435 methionyl-tRNA formyltransferase YP_003032545.1 2830601 R 478434 CDS YP_003032546.1 253799545 8160934 2831736..2832560 1 NC_012943.1 methyltransferase 2832560 8160934 TBMG_02575 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032546.1 2831736 D 478434 CDS YP_003032547.1 253799546 8160935 complement(2832632..2833159) 1 NC_012943.1 transcriptional regulator 2833159 8160935 TBMG_02576 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032547.1 2832632 R 478434 CDS YP_003032548.1 253799547 8160936 2833283..2834107 1 NC_012943.1 methyltransferase 2834107 8160936 TBMG_02577 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032548.1 2833283 D 478434 CDS YP_003032549.1 253799548 8160937 complement(2834125..2836092) 1 NC_012943.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 2836092 8160937 TBMG_02578 Mycobacterium tuberculosis KZN 1435 primosome assembly protein PriA YP_003032549.1 2834125 R 478434 CDS YP_003032550.1 253799549 8160938 complement(2836173..2836958) 1 NC_012943.1 hypothetical protein 2836958 8160938 TBMG_02579 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032550.1 2836173 R 478434 CDS YP_003032551.1 253799550 8160940 2836909..2837871 1 NC_012943.1 lipase lipH 2837871 8160940 TBMG_02580 Mycobacterium tuberculosis KZN 1435 lipase lipH YP_003032551.1 2836909 D 478434 CDS YP_003032552.1 253799551 8160939 2837896..2838855 1 NC_012943.1 lipase lipH 2838855 8160939 TBMG_02581 Mycobacterium tuberculosis KZN 1435 lipase lipH YP_003032552.1 2837896 D 478434 CDS YP_003032553.1 253799552 8160941 2838938..2839195 1 NC_012943.1 antitoxin 2839195 8160941 TBMG_02582 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032553.1 2838938 D 478434 CDS YP_003032554.1 253799553 8160942 2839192..2839593 1 NC_012943.1 toxin 2839593 8160942 TBMG_02583 Mycobacterium tuberculosis KZN 1435 toxin YP_003032554.1 2839192 D 478434 CDS YP_003032555.1 253799554 8160943 2839848..2841092 1 NC_012943.1 PE-PGRS family protein 2841092 8160943 TBMG_02584 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032555.1 2839848 D 478434 CDS YP_003032556.1 253799555 8160944 2841254..2841577 1 NC_012943.1 PE-PGRS family protein 2841577 8160944 TBMG_04065 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032556.1 2841254 D 478434 CDS YP_003032557.1 253799556 8160945 complement(2841623..2842657) 1 NC_012943.1 transcriptional regulator 2842657 8160945 TBMG_02585 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032557.1 2841623 R 478434 CDS YP_003032558.1 253799557 8160946 2842735..2844120 1 NC_012943.1 cytochrome P450 132 cyp132 2844120 8160946 TBMG_02586 Mycobacterium tuberculosis KZN 1435 cytochrome P450 132 cyp132 YP_003032558.1 2842735 D 478434 CDS YP_003032559.1 253799558 8160947 2844117..2845595 1 NC_012943.1 monooxygenase 2845595 8160947 TBMG_02587 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003032559.1 2844117 D 478434 CDS YP_003032560.1 253799559 8160948 complement(2845668..2846888) 1 NC_012943.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2846888 8160948 TBMG_02588 Mycobacterium tuberculosis KZN 1435 S-adenosylmethionine synthetase YP_003032560.1 2845668 R 478434 CDS YP_003032561.1 253799560 8160949 complement(2847007..2848263) 1 NC_012943.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 2848263 8160949 TBMG_02589 Mycobacterium tuberculosis KZN 1435 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_003032561.1 2847007 R 478434 CDS YP_003032562.1 253799561 8160950 complement(2848279..2848611) 1 NC_012943.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2848611 8160950 TBMG_02590 Mycobacterium tuberculosis KZN 1435 DNA-directed RNA polymerase subunit omega YP_003032562.1 2848279 R 478434 CDS YP_003032563.1 253799562 8160951 complement(2848677..2849330) 1 NC_012943.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2849330 gmk 8160951 gmk Mycobacterium tuberculosis KZN 1435 guanylate kinase YP_003032563.1 2848677 R 478434 CDS YP_003032564.1 253799563 8160952 complement(2849438..2850010) 1 NC_012943.1 integration host factor mihF 2850010 8160952 TBMG_02592 Mycobacterium tuberculosis KZN 1435 integration host factor mihF YP_003032564.1 2849438 R 478434 CDS YP_003032565.1 253799564 8160953 complement(2850316..2851935) 1 NC_012943.1 PPE family protein 2851935 8160953 TBMG_02593 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032565.1 2850316 R 478434 CDS YP_003032566.1 253799565 8160954 complement(2851932..2852240) 1 NC_012943.1 PE family protein 2852240 8160954 TBMG_02594 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032566.1 2851932 R 478434 CDS YP_003032567.1 253799566 8160955 complement(2852435..2853259) 1 NC_012943.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2853259 pyrF 8160955 pyrF Mycobacterium tuberculosis KZN 1435 orotidine 5'-phosphate decarboxylase YP_003032567.1 2852435 R 478434 CDS YP_003032568.1 253799567 8160956 complement(2853256..2856603) 1 NC_012943.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 2856603 carB 8160956 carB Mycobacterium tuberculosis KZN 1435 carbamoyl phosphate synthase large subunit YP_003032568.1 2853256 R 478434 CDS YP_003032569.1 253799568 8160957 complement(2856603..2857733) 1 NC_012943.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 2857733 8160957 TBMG_02597 Mycobacterium tuberculosis KZN 1435 carbamoyl phosphate synthase small subunit YP_003032569.1 2856603 R 478434 CDS YP_003032570.1 253799569 8160958 complement(2857730..2858227) 1 NC_012943.1 hypothetical protein 2858227 8160958 TBMG_02598 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032570.1 2857730 R 478434 CDS YP_003032571.1 253799570 8160959 complement(2858224..2859516) 1 NC_012943.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 2859516 pyrC 8160959 pyrC Mycobacterium tuberculosis KZN 1435 dihydroorotase YP_003032571.1 2858224 R 478434 CDS YP_003032572.1 253799571 8160960 complement(2859513..2860472) 1 NC_012943.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 2860472 pyrB 8160960 pyrB Mycobacterium tuberculosis KZN 1435 aspartate carbamoyltransferase YP_003032572.1 2859513 R 478434 CDS YP_003032573.1 253799572 8160961 complement(2860469..2861050) 1 NC_012943.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 2861050 8160961 TBMG_02601 Mycobacterium tuberculosis KZN 1435 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_003032573.1 2860469 R 478434 CDS YP_003032574.1 253799573 8164494 2861049..2862476 1 NC_012943.1 hypothetical protein 2862476 8164494 TBMG_02602 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032574.1 2861049 D 478434 CDS YP_003032575.1 253799574 8160962 2862487..2863125 1 NC_012943.1 transferase 2863125 8160962 TBMG_02603 Mycobacterium tuberculosis KZN 1435 transferase YP_003032575.1 2862487 D 478434 CDS YP_003032576.1 253799575 8164495 complement(2863063..2864556) 1 NC_012943.1 hypothetical protein 2864556 8164495 TBMG_02604 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032576.1 2863063 R 478434 CDS YP_003032577.1 253799576 8162054 complement(2864553..2865872) 1 NC_012943.1 hypothetical protein 2865872 8162054 TBMG_02605 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032577.1 2864553 R 478434 CDS YP_003032578.1 253799577 8162166 2866174..2866632 1 NC_012943.1 hypothetical protein 2866632 8162166 TBMG_02606 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032578.1 2866174 D 478434 CDS YP_003032579.1 253799578 8162167 complement(2866712..2867692) 1 NC_012943.1 glycolipid sulfotransferase 2867692 8162167 TBMG_02607 Mycobacterium tuberculosis KZN 1435 glycolipid sulfotransferase YP_003032579.1 2866712 R 478434 CDS YP_003032580.1 253799579 8162168 complement(2867698..2868879) 1 NC_012943.1 hypothetical protein 2868879 8162168 TBMG_02608 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032580.1 2867698 R 478434 CDS YP_003032581.1 253799580 8162169 complement(2868876..2870345) 1 NC_012943.1 hypothetical protein 2870345 8162169 TBMG_02609 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032581.1 2868876 R 478434 CDS YP_003032582.1 253799581 8162170 complement(2870541..2871326) 1 NC_012943.1 hypothetical protein 2871326 8162170 TBMG_02610 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032582.1 2870541 R 478434 CDS YP_003032583.1 253799582 8162171 2871629..2872834 1 NC_012943.1 hypothetical protein 2872834 8162171 TBMG_02611 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032583.1 2871629 D 478434 CDS YP_003032584.1 253799583 8162172 complement(2872906..2873166) 1 NC_012943.1 hypothetical protein 2873166 8162172 TBMG_04066 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032584.1 2872906 R 478434 CDS YP_003032585.1 253799584 8162173 complement(2873135..2873956) 1 NC_012943.1 hypothetical protein 2873956 8162173 TBMG_04067 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032585.1 2873135 R 478434 CDS YP_003032586.1 253799585 8162174 2874177..2874563 1 NC_012943.1 anti-anti-sigma factor rsfA 2874563 8162174 TBMG_02613 Mycobacterium tuberculosis KZN 1435 anti-anti-sigma factor rsfA YP_003032586.1 2874177 D 478434 CDS YP_003032587.1 253799586 8162175 2874702..2876663 1 NC_012943.1 hypothetical protein 2876663 8162175 TBMG_02614 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032587.1 2874702 D 478434 CDS YP_003032588.1 253799587 8162176 2876954..2877739 1 NC_012943.1 hypothetical protein 2877739 8162176 TBMG_02615 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032588.1 2876954 D 478434 CDS YP_003032589.1 253799588 8162177 2877736..2878398 1 NC_012943.1 hypothetical protein 2878398 8162177 TBMG_02616 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032589.1 2877736 D 478434 CDS YP_003032590.1 253799589 8162178 2878713..2879903 1 NC_012943.1 PPE family protein 2879903 8162178 TBMG_02617 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032590.1 2878713 D 478434 CDS YP_003032591.1 253799590 8162179 complement(2879976..2880998) 1 NC_012943.1 oxidoreductase 2880998 8162179 TBMG_02618 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032591.1 2879976 R 478434 CDS YP_003032592.1 253799591 8162180 2881137..2881373 1 NC_012943.1 hypothetical protein 2881373 8162180 TBMG_04068 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032592.1 2881137 D 478434 CDS YP_003032593.1 253799592 8162181 complement(2881421..2882173) 1 NC_012943.1 transcriptional regulator 2882173 8162181 TBMG_02619 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032593.1 2881421 R 478434 CDS YP_003032594.1 253799593 8162182 complement(2882255..2884867) 1 NC_012943.1 transcriptional regulator 2884867 8162182 TBMG_04069 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032594.1 2882255 R 478434 CDS YP_003032595.1 253799594 8162183 complement(2884836..2885735) 1 NC_012943.1 transcriptional regulator 2885735 8162183 TBMG_04070 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032595.1 2884836 R 478434 CDS YP_003032596.1 253799595 8162184 2886131..2887054 1 NC_012943.1 hypothetical protein 2887054 8162184 TBMG_02621 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032596.1 2886131 D 478434 CDS YP_003032597.1 253799596 8162185 2887527..2888318 1 NC_012943.1 hypothetical protein 2888318 8162185 TBMG_02622 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032597.1 2887527 D 478434 CDS YP_003032598.1 253799597 8162186 2888315..2890462 1 NC_012943.1 hypothetical protein 2890462 8162186 TBMG_02623 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032598.1 2888315 D 478434 CDS YP_003032599.1 253799598 8162187 2890471..2892342 1 NC_012943.1 hypothetical protein 2892342 8162187 TBMG_02624 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032599.1 2890471 D 478434 CDS YP_003032600.1 253799599 8162188 2892362..2893147 1 NC_012943.1 transcriptional regulator 2893147 8162188 TBMG_02625 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032600.1 2892362 D 478434 CDS YP_003032601.1 253799600 8162189 complement(2893213..2893584) 1 NC_012943.1 hypothetical protein 2893584 8162189 TBMG_02626 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032601.1 2893213 R 478434 CDS YP_003032602.1 253799601 8162190 complement(2893787..2894116) 1 NC_012943.1 hypothetical protein 2894116 8162190 TBMG_02627 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032602.1 2893787 R 478434 CDS YP_003032603.1 253799602 8162191 complement(2894113..2894856) 1 NC_012943.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2894856 fabG 8162191 fabG Mycobacterium tuberculosis KZN 1435 3-ketoacyl-ACP reductase YP_003032603.1 2894113 R 478434 CDS YP_003032604.1 253799603 8162192 complement(2894985..2896724) 1 NC_012943.1 drugs-transport transmembrane ATP-binding protein ABC transporter 2896724 8162192 TBMG_02629 Mycobacterium tuberculosis KZN 1435 drugs-transport transmembrane ATP-binding protein ABC transporter YP_003032604.1 2894985 R 478434 CDS YP_003032605.1 253799604 8162193 complement(2896721..2899300) 1 NC_012943.1 drugs-transport transmembrane ATP-binding protein ABC transporter 2899300 8162193 TBMG_02630 Mycobacterium tuberculosis KZN 1435 drugs-transport transmembrane ATP-binding protein ABC transporter YP_003032605.1 2896721 R 478434 CDS YP_003032606.1 253799605 8162195 2899742..2900374 1 NC_012943.1 hypothetical protein 2900374 8162195 TBMG_02631 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032606.1 2899742 D 478434 CDS YP_003032607.1 253799606 8162196 complement(2900341..2901501) 1 NC_012943.1 acyl-CoA dehydrogenase 2901501 8162196 TBMG_02632 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003032607.1 2900341 R 478434 CDS YP_003032608.1 253799607 8162197 complement(2901501..2903066) 1 NC_012943.1 converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; long-chain fatty acid--ACP ligase 2903066 8162197 TBMG_02633 Mycobacterium tuberculosis KZN 1435 long-chain fatty acid--ACP ligase YP_003032608.1 2901501 R 478434 CDS YP_003032609.1 253799608 8162198 complement(2903059..2903379) 1 NC_012943.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 2903379 8162198 TBMG_02634 Mycobacterium tuberculosis KZN 1435 acyl carrier protein YP_003032609.1 2903059 R 478434 CDS YP_003032610.1 253799609 8162199 2903424..2903804 1 NC_012943.1 hypothetical protein 2903804 8162199 TBMG_02635 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032610.1 2903424 D 478434 CDS YP_003032611.1 253799610 8162200 2903801..2904163 1 NC_012943.1 hypothetical protein 2904163 8162200 TBMG_02636 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032611.1 2903801 D 478434 CDS YP_003032612.1 253799611 8162201 complement(2904160..2904774) 1 NC_012943.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 2904774 8162201 TBMG_02637 Mycobacterium tuberculosis KZN 1435 deoxyribonucleotide triphosphate pyrophosphatase YP_003032612.1 2904160 R 478434 CDS YP_003032613.1 253799612 8162202 complement(2904813..2905592) 1 NC_012943.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 2905592 rph 8162202 rph Mycobacterium tuberculosis KZN 1435 ribonuclease PH YP_003032613.1 2904813 R 478434 CDS YP_003032614.1 253799613 8162203 complement(2905609..2906430) 1 NC_012943.1 hypothetical protein 2906430 8162203 TBMG_02639 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032614.1 2905609 R 478434 CDS YP_003032615.1 253799614 8162204 complement(2906457..2907272) 1 NC_012943.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 2907272 8162204 TBMG_02640 Mycobacterium tuberculosis KZN 1435 glutamate racemase YP_003032615.1 2906457 R 478434 CDS YP_003032616.1 253799615 8162205 complement(2907269..2907991) 1 NC_012943.1 hypothetical protein 2907991 8162205 TBMG_02641 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032616.1 2907269 R 478434 CDS YP_003032617.1 253799616 8162206 complement(2907982..2908953) 1 NC_012943.1 cysteine synthase B cysM 2908953 8162206 TBMG_02642 Mycobacterium tuberculosis KZN 1435 cysteine synthase B cysM YP_003032617.1 2907982 R 478434 CDS YP_003032618.1 253799617 8162207 complement(2908963..2909244) 1 NC_012943.1 hypothetical protein 2909244 8162207 TBMG_02643 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032618.1 2908963 R 478434 CDS YP_003032619.1 253799618 8162208 complement(2909266..2909706) 1 NC_012943.1 hypothetical protein 2909706 8162208 TBMG_02644 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032619.1 2909266 R 478434 CDS YP_003032620.1 253799619 8162209 complement(2909714..2910748) 1 NC_012943.1 hydrolase 2910748 8162209 TBMG_02645 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003032620.1 2909714 R 478434 CDS YP_003032621.1 253799620 8162210 complement(2910765..2911421) 1 NC_012943.1 transcriptional regulator 2911421 8162210 TBMG_02646 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032621.1 2910765 R 478434 CDS YP_003032622.1 253799621 8162211 complement(2911381..2911686) 1 NC_012943.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 2911686 clpS 8162211 clpS Mycobacterium tuberculosis KZN 1435 ATP-dependent Clp protease adaptor protein ClpS YP_003032622.1 2911381 R 478434 CDS YP_003032623.1 253799622 8162212 2911788..2913134 1 NC_012943.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2913134 8162212 TBMG_02648 Mycobacterium tuberculosis KZN 1435 nicotinate phosphoribosyltransferase YP_003032623.1 2911788 D 478434 CDS YP_003032624.1 253799623 8162213 2913158..2915152 1 NC_012943.1 ATP-dependent helicase dinG 2915152 8162213 TBMG_02649 Mycobacterium tuberculosis KZN 1435 ATP-dependent helicase dinG YP_003032624.1 2913158 D 478434 CDS YP_003032625.1 253799624 8162214 complement(2915192..2917783) 1 NC_012943.1 glycogen phosphorylase glgP 2917783 8162214 TBMG_02650 Mycobacterium tuberculosis KZN 1435 glycogen phosphorylase glgP YP_003032625.1 2915192 R 478434 CDS YP_003032626.1 253799625 8162215 2917922..2920027 1 NC_012943.1 glucanase glgE 2920027 8162215 TBMG_02651 Mycobacterium tuberculosis KZN 1435 glucanase glgE YP_003032626.1 2917922 D 478434 CDS YP_003032627.1 253799626 8162216 2920035..2922230 1 NC_012943.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 2922230 8162216 TBMG_02652 Mycobacterium tuberculosis KZN 1435 glycogen branching enzyme YP_003032627.1 2920035 D 478434 CDS YP_003032628.1 253799627 8162217 2922382..2924193 1 NC_012943.1 PE-PGRS family protein 2924193 8162217 TBMG_04071 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032628.1 2922382 D 478434 CDS YP_003032629.1 253799628 8162218 complement(2924272..2925186) 1 NC_012943.1 thioredoxin 2925186 8162218 TBMG_02655 Mycobacterium tuberculosis KZN 1435 thioredoxin YP_003032629.1 2924272 R 478434 CDS YP_003032630.1 253799629 8162219 complement(2925316..2926485) 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 2926485 8162219 TBMG_02656 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003032630.1 2925316 R 478434 CDS YP_003032631.1 253799630 8162221 2926397..2926579 1 NC_012943.1 hypothetical protein 2926579 8162221 TBMG_04072 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032631.1 2926397 D 478434 CDS YP_003032632.1 253799631 8162220 2926576..2927034 1 NC_012943.1 hypothetical protein 2927034 8162220 TBMG_02657 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032632.1 2926576 D 478434 CDS YP_003032633.1 253799632 8162222 complement(2927069..2927365) 1 NC_012943.1 hypothetical protein 2927365 8162222 TBMG_02658 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032633.1 2927069 R 478434 CDS YP_003032634.1 253799633 8162223 complement(2927388..2928068) 1 NC_012943.1 hypothetical protein 2928068 8162223 TBMG_02659 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032634.1 2927388 R 478434 CDS YP_003032635.1 253799634 8162224 2928130..2929833 1 NC_012943.1 adenylate cyclase 2929833 8162224 TBMG_02660 Mycobacterium tuberculosis KZN 1435 adenylate cyclase YP_003032635.1 2928130 D 478434 CDS YP_003032636.1 253799635 8162225 2929846..2931453 1 NC_012943.1 adenylate cyclase 2931453 8162225 TBMG_02661 Mycobacterium tuberculosis KZN 1435 adenylate cyclase YP_003032636.1 2929846 D 478434 CDS YP_003032637.1 253799636 8162226 2931523..2933148 1 NC_012943.1 adenylate cyclase 2933148 8162226 TBMG_02662 Mycobacterium tuberculosis KZN 1435 adenylate cyclase YP_003032637.1 2931523 D 478434 CDS YP_003032638.1 253799637 8162227 2933229..2934719 1 NC_012943.1 ada regulatory protein alkA 2934719 8162227 TBMG_02663 Mycobacterium tuberculosis KZN 1435 ada regulatory protein alkA YP_003032638.1 2933229 D 478434 CDS YP_003032639.1 253799638 8162228 2934716..2935213 1 NC_012943.1 methylated-DNA-protein-cysteine methyltransferase ogt 2935213 8162228 TBMG_02664 Mycobacterium tuberculosis KZN 1435 methylated-DNA-protein-cysteine methyltransferase ogt YP_003032639.1 2934716 D 478434 CDS YP_003032640.1 253799639 8161235 complement(2940771..2942027) 1 NC_012943.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2942027 8161235 TBMG_02665 Mycobacterium tuberculosis KZN 1435 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_003032640.1 2940771 R 478434 CDS YP_003032641.1 253799640 8162230 2942096..2942677 1 NC_012943.1 ATP:cob(I)alamin adenosyltransferase 2942677 8162230 TBMG_02666 Mycobacterium tuberculosis KZN 1435 ATP:cob(I)alamin adenosyltransferase YP_003032641.1 2942096 D 478434 CDS YP_003032642.1 253799641 8162231 2942843..2944177 1 NC_012943.1 transposase 2944177 8162231 TBMG_02667 Mycobacterium tuberculosis KZN 1435 transposase YP_003032642.1 2942843 D 478434 CDS YP_003032643.1 253799642 8162232 complement(2944217..2944660) 1 NC_012943.1 hypothetical protein 2944660 8162232 TBMG_02668 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032643.1 2944217 R 478434 CDS YP_003032644.1 253799643 8162233 complement(2944668..2945099) 1 NC_012943.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 2945099 atpC 8162233 atpC Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit epsilon YP_003032644.1 2944668 R 478434 CDS YP_003032645.1 253799644 8162234 complement(2945047..2946507) 1 NC_012943.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 2946507 8162234 TBMG_02670 Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit beta YP_003032645.1 2945047 R 478434 CDS YP_003032646.1 253799645 8162235 complement(2946547..2947464) 1 NC_012943.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 2947464 8162235 TBMG_02671 Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit gamma YP_003032646.1 2946547 R 478434 CDS YP_003032647.1 253799646 8162236 complement(2947471..2949120) 1 NC_012943.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 2949120 8162236 TBMG_02672 Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit alpha YP_003032647.1 2947471 R 478434 CDS YP_003032648.1 253799647 8162237 complement(2949165..2950505) 1 NC_012943.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 2950505 8162237 TBMG_02673 Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit delta YP_003032648.1 2949165 R 478434 CDS YP_003032649.1 253799648 8162238 complement(2950512..2951027) 1 NC_012943.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 2951027 8162238 TBMG_02674 Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit B YP_003032649.1 2950512 R 478434 CDS YP_003032650.1 253799649 8162239 complement(2951058..2951345) 1 NC_012943.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 2951345 8162239 TBMG_02675 Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit C YP_003032650.1 2951058 R 478434 CDS YP_003032651.1 253799650 8162240 complement(2951352..2952104) 1 NC_012943.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 2952104 8162240 TBMG_02676 Mycobacterium tuberculosis KZN 1435 ATP synthase F0F1 subunit A YP_003032651.1 2951352 R 478434 CDS YP_003032652.1 253799651 8162241 complement(2952097..2952582) 1 NC_012943.1 hypothetical protein 2952582 8162241 TBMG_02677 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032652.1 2952097 R 478434 CDS YP_003032653.1 253799652 8162242 complement(2952839..2954053) 1 NC_012943.1 undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe 2954053 8162242 TBMG_02678 Mycobacterium tuberculosis KZN 1435 undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase rfe YP_003032653.1 2952839 R 478434 CDS YP_003032654.1 253799653 8162243 complement(2954137..2954790) 1 NC_012943.1 Sua5/YciO/YrdC/YwlC family protein 2954790 8162243 TBMG_02679 Mycobacterium tuberculosis KZN 1435 Sua5/YciO/YrdC/YwlC family protein YP_003032654.1 2954137 R 478434 CDS YP_003032655.1 253799654 8162244 complement(2954806..2955783) 1 NC_012943.1 hypothetical protein 2955783 8162244 TBMG_02680 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032655.1 2954806 R 478434 CDS YP_003032656.1 253799655 8162245 complement(2955780..2956853) 1 NC_012943.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2956853 prfA 8162245 prfA Mycobacterium tuberculosis KZN 1435 peptide chain release factor 1 YP_003032656.1 2955780 R 478434 CDS YP_003032657.1 253799656 8161126 complement(2956943..2957185) 1 NC_012943.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 2957185 rpmE 8161126 rpmE Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L31 YP_003032657.1 2956943 R 478434 CDS YP_003032658.1 253799657 8161127 complement(2957336..2959144) 1 NC_012943.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 2959144 8161127 TBMG_02683 Mycobacterium tuberculosis KZN 1435 transcription termination factor Rho YP_003032658.1 2957336 R 478434 CDS YP_003032659.1 253799658 8161128 complement(2959401..2960351) 1 NC_012943.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2960351 8161128 TBMG_02684 Mycobacterium tuberculosis KZN 1435 homoserine kinase YP_003032659.1 2959401 R 478434 CDS YP_003032660.1 253799659 8161129 complement(2960512..2961594) 1 NC_012943.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 2961594 8161129 TBMG_02685 Mycobacterium tuberculosis KZN 1435 threonine synthase YP_003032660.1 2960512 R 478434 CDS YP_003032661.1 253799660 8161130 complement(2961591..2962916) 1 NC_012943.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 2962916 8161130 TBMG_02686 Mycobacterium tuberculosis KZN 1435 homoserine dehydrogenase YP_003032661.1 2961591 R 478434 CDS YP_003032662.1 253799661 8161131 complement(2962920..2964263) 1 NC_012943.1 diaminopimelate decarboxylase lysA 2964263 8161131 TBMG_02687 Mycobacterium tuberculosis KZN 1435 diaminopimelate decarboxylase lysA YP_003032662.1 2962920 R 478434 CDS YP_003032663.1 253799662 8161132 complement(2964260..2965912) 1 NC_012943.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2965912 argS 8161132 argS Mycobacterium tuberculosis KZN 1435 arginyl-tRNA synthetase YP_003032663.1 2964260 R 478434 CDS YP_003032664.1 253799663 8161134 2966457..2966792 1 NC_012943.1 hypothetical protein 2966792 8161134 TBMG_02689 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032664.1 2966457 D 478434 CDS YP_003032665.1 253799664 8161135 complement(2966919..2967233) 1 NC_012943.1 hypothetical protein 2967233 8161135 TBMG_02690 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032665.1 2966919 R 478434 CDS YP_003032666.1 253799665 8161136 2967244..2968809 1 NC_012943.1 hypothetical protein 2968809 8161136 TBMG_02691 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032666.1 2967244 D 478434 CDS YP_003032667.1 253799666 8161137 complement(2968892..2969524) 1 NC_012943.1 hypothetical protein 2969524 8161137 TBMG_02692 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032667.1 2968892 R 478434 CDS YP_003032668.1 253799667 8161138 complement(2969573..2970943) 1 NC_012943.1 hypothetical protein 2970943 8161138 TBMG_02693 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032668.1 2969573 R 478434 CDS YP_003032669.1 253799668 8161139 complement(2971001..2971486) 1 NC_012943.1 hypothetical protein 2971486 8161139 TBMG_02694 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032669.1 2971001 R 478434 CDS YP_003032670.1 253799669 8161140 complement(2971540..2973384) 1 NC_012943.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein 2973384 8161140 TBMG_02695 Mycobacterium tuberculosis KZN 1435 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein YP_003032670.1 2971540 R 478434 CDS YP_003032671.1 253799670 8161141 complement(2973384..2974382) 1 NC_012943.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2974382 8161141 TBMG_02696 Mycobacterium tuberculosis KZN 1435 sulfate adenylyltransferase subunit 2 YP_003032671.1 2973384 R 478434 CDS YP_003032672.1 253799671 8161142 complement(2974476..2974967) 1 NC_012943.1 hypothetical protein 2974967 8161142 TBMG_02697 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032672.1 2974476 R 478434 CDS YP_003032673.1 253799672 8161143 2975174..2976151 1 NC_012943.1 hypothetical protein 2976151 8161143 TBMG_02698 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032673.1 2975174 D 478434 CDS YP_003032674.1 253799673 8161144 2976148..2977023 1 NC_012943.1 hypothetical protein 2977023 8161144 TBMG_02699 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032674.1 2976148 D 478434 CDS YP_003032675.1 253799674 8161145 2977020..2978858 1 NC_012943.1 peptide ABC transporter ATP-binding protein 2978858 8161145 TBMG_02700 Mycobacterium tuberculosis KZN 1435 peptide ABC transporter ATP-binding protein YP_003032675.1 2977020 D 478434 CDS YP_003032676.1 253799675 8161146 2978851..2980626 1 NC_012943.1 periplasmic oligopeptide-binding lipoprotein oppA 2980626 8161146 TBMG_02701 Mycobacterium tuberculosis KZN 1435 periplasmic oligopeptide-binding lipoprotein oppA YP_003032676.1 2978851 D 478434 CDS YP_003032677.1 253799676 8161147 complement(2980643..2982229) 1 NC_012943.1 dehydrogenase FAD flavoprotein gmc oxidoreductase 2982229 8161147 TBMG_02702 Mycobacterium tuberculosis KZN 1435 dehydrogenase FAD flavoprotein gmc oxidoreductase YP_003032677.1 2980643 R 478434 CDS YP_003032678.1 253799677 8161148 complement(2982250..2984877) 1 NC_012943.1 hypothetical protein 2984877 8161148 TBMG_02703 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032678.1 2982250 R 478434 CDS YP_003032679.1 253799678 8161149 complement(2984874..2986127) 1 NC_012943.1 hypothetical protein 2986127 8161149 TBMG_02704 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032679.1 2984874 R 478434 CDS YP_003032680.1 253799679 8161150 2986347..2986853 1 NC_012943.1 hypothetical protein 2986853 8161150 TBMG_02705 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032680.1 2986347 D 478434 CDS YP_003032681.1 253799680 8161151 complement(2986998..2987540) 1 NC_012943.1 hypothetical protein 2987540 8161151 TBMG_02706 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032681.1 2986998 R 478434 CDS YP_003032682.1 253799681 8161152 complement(2987537..2988094) 1 NC_012943.1 hypothetical protein 2988094 8161152 TBMG_02707 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032682.1 2987537 R 478434 CDS YP_003032683.1 253799682 8161153 2988241..2989989 1 NC_012943.1 drugs-transport transmembrane ATP-binding protein ABC transporter 2989989 8161153 TBMG_02708 Mycobacterium tuberculosis KZN 1435 drugs-transport transmembrane ATP-binding protein ABC transporter YP_003032683.1 2988241 D 478434 CDS YP_003032684.1 253799683 8161154 2989986..2991881 1 NC_012943.1 drugs-transport transmembrane ATP-binding protein ABC transporter 2991881 8161154 TBMG_02709 Mycobacterium tuberculosis KZN 1435 drugs-transport transmembrane ATP-binding protein ABC transporter YP_003032684.1 2989986 D 478434 CDS YP_003032685.1 253799684 8161155 2991989..2992330 1 NC_012943.1 hypothetical protein 2992330 8161155 TBMG_02710 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032685.1 2991989 D 478434 CDS YP_003032686.1 253799685 8161156 2992504..2993277 1 NC_012943.1 hypothetical protein 2993277 8161156 TBMG_02711 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032686.1 2992504 D 478434 CDS YP_003032687.1 253799686 8161157 2993338..2993712 1 NC_012943.1 hypothetical protein 2993712 8161157 TBMG_02712 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032687.1 2993338 D 478434 CDS YP_003032688.1 253799687 8161158 2993935..2994633 1 NC_012943.1 hypothetical protein 2994633 8161158 TBMG_02713 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032688.1 2993935 D 478434 CDS YP_003032689.1 253799688 8161159 2994944..2996110 1 NC_012943.1 transcriptional regulator embR 2996110 8161159 TBMG_02714 Mycobacterium tuberculosis KZN 1435 transcriptional regulator embR YP_003032689.1 2994944 D 478434 CDS YP_003032690.1 253799689 8161160 2996451..2998331 1 NC_012943.1 Ser/Thr protein kinase 2998331 8161160 TBMG_02715 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003032690.1 2996451 D 478434 CDS YP_003032691.1 253799690 8161161 complement(2998351..2999031) 1 NC_012943.1 hypothetical protein 2999031 8161161 TBMG_02716 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032691.1 2998351 R 478434 CDS YP_003032692.1 253799691 8161162 complement(2999204..3000397) 1 NC_012943.1 adenylyl cyclase 3000397 8161162 TBMG_02717 Mycobacterium tuberculosis KZN 1435 adenylyl cyclase YP_003032692.1 2999204 R 478434 CDS YP_003032693.1 253799692 8161163 complement(3000472..3001860) 1 NC_012943.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 3001860 8161163 TBMG_02718 Mycobacterium tuberculosis KZN 1435 amidase YP_003032693.1 3000472 R 478434 CDS YP_003032694.1 253799693 8161164 3001919..3002353 1 NC_012943.1 hypothetical protein 3002353 8161164 TBMG_02719 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032694.1 3001919 D 478434 CDS YP_003032695.1 253799694 8161165 3002334..3002807 1 NC_012943.1 hypothetical protein 3002807 8161165 TBMG_02720 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032695.1 3002334 D 478434 CDS YP_003032696.1 253799695 8161166 complement(3002933..3004060) 1 NC_012943.1 hypothetical protein 3004060 8161166 TBMG_02721 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032696.1 3002933 R 478434 CDS YP_003032697.1 253799696 8161167 complement(3004053..3004952) 1 NC_012943.1 hypothetical protein 3004952 8161167 TBMG_02722 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032697.1 3004053 R 478434 CDS YP_003032698.1 253799697 8161169 3004951..3006210 1 NC_012943.1 membrane transporter 3006210 8161169 TBMG_02723 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003032698.1 3004951 D 478434 CDS YP_003032699.1 253799698 8161168 3006207..3007574 1 NC_012943.1 oxidoreductase 3007574 8161168 TBMG_02724 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032699.1 3006207 D 478434 CDS YP_003032700.1 253799699 8161170 3007700..3008905 1 NC_012943.1 cytochrome P450 130 cyp130 3008905 8161170 TBMG_02725 Mycobacterium tuberculosis KZN 1435 cytochrome P450 130 cyp130 YP_003032700.1 3007700 D 478434 CDS YP_003032701.1 253799700 8161171 3008905..3009513 1 NC_012943.1 transcriptional regulator 3009513 8161171 TBMG_02726 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032701.1 3008905 D 478434 CDS YP_003032702.1 253799701 8161172 complement(3009482..3010633) 1 NC_012943.1 acyltransferase 3010633 8161172 TBMG_02727 Mycobacterium tuberculosis KZN 1435 acyltransferase YP_003032702.1 3009482 R 478434 CDS YP_003032703.1 253799702 8161173 complement(3010630..3012321) 1 NC_012943.1 cold shock deaD-box protein A deaD 3012321 8161173 TBMG_02728 Mycobacterium tuberculosis KZN 1435 cold shock deaD-box protein A deaD YP_003032703.1 3010630 R 478434 CDS YP_003032704.1 253799703 8161174 3012387..3012995 1 NC_012943.1 hypothetical protein 3012995 8161174 TBMG_02729 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032704.1 3012387 D 478434 CDS YP_003032705.1 253799704 8161175 3013051..3016470 1 NC_012943.1 hypothetical protein 3016470 8161175 TBMG_02730 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032705.1 3013051 D 478434 CDS YP_003032706.1 253799705 8161176 complement(3016373..3018112) 1 NC_012943.1 hypothetical protein 3018112 8161176 TBMG_02731 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032706.1 3016373 R 478434 CDS YP_003032707.1 253799706 8161177 3018309..3019097 1 NC_012943.1 hypothetical protein 3019097 8161177 TBMG_02732 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032707.1 3018309 D 478434 CDS YP_003032708.1 253799707 8161178 3019239..3022934 1 NC_012943.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase 3022934 kgd 8161178 kgd Mycobacterium tuberculosis KZN 1435 alpha-ketoglutarate decarboxylase YP_003032708.1 3019239 D 478434 CDS YP_003032709.1 253799708 8161179 3023047..3023316 1 NC_012943.1 antitoxin 3023316 8161179 TBMG_02734 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032709.1 3023047 D 478434 CDS YP_003032710.1 253799709 8161180 3023313..3023606 1 NC_012943.1 toxin 3023606 8161180 TBMG_02735 Mycobacterium tuberculosis KZN 1435 toxin YP_003032710.1 3023313 D 478434 CDS YP_003032711.1 253799710 8161181 3023663..3024493 1 NC_012943.1 short-chain type dehydrogenase/reductase 3024493 8161181 TBMG_02736 Mycobacterium tuberculosis KZN 1435 short-chain type dehydrogenase/reductase YP_003032711.1 3023663 D 478434 CDS YP_003032712.1 253799711 8161182 complement(3024574..3025434) 1 NC_012943.1 hypothetical protein 3025434 8161182 TBMG_02737 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032712.1 3024574 R 478434 CDS YP_003032713.1 253799712 8161183 3025542..3027302 1 NC_012943.1 PE-PGRS family protein 3027302 8161183 TBMG_02738 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032713.1 3025542 D 478434 CDS YP_003032714.1 253799713 8161184 complement(3027325..3027756) 1 NC_012943.1 toxin 3027756 8161184 TBMG_02739 Mycobacterium tuberculosis KZN 1435 toxin YP_003032714.1 3027325 R 478434 CDS YP_003032715.1 253799714 8161185 complement(3027753..3028013) 1 NC_012943.1 antitoxin 3028013 8161185 TBMG_02740 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032715.1 3027753 R 478434 CDS YP_003032716.1 253799715 8161186 complement(3028089..3029078) 1 NC_012943.1 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 3029078 8161186 TBMG_02741 Mycobacterium tuberculosis KZN 1435 malate dehydrogenase YP_003032716.1 3028089 R 478434 CDS YP_003032717.1 253799716 8161187 3029249..3030349 1 NC_012943.1 hypothetical protein 3030349 8161187 TBMG_02742 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032717.1 3029249 D 478434 CDS YP_003032718.1 253799717 8161188 complement(3030426..3031607) 1 NC_012943.1 sugar ABC transporter 3031607 8161188 TBMG_02743 Mycobacterium tuberculosis KZN 1435 sugar ABC transporter YP_003032718.1 3030426 R 478434 CDS YP_003032719.1 253799718 8161189 complement(3031612..3032436) 1 NC_012943.1 hypothetical protein 3032436 8161189 TBMG_02744 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032719.1 3031612 R 478434 CDS YP_003032720.1 253799719 8161190 complement(3032441..3033364) 1 NC_012943.1 hypothetical protein 3033364 8161190 TBMG_02745 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032720.1 3032441 R 478434 CDS YP_003032721.1 253799720 8161191 complement(3033361..3034767) 1 NC_012943.1 sugar-binding lipoprotein lpqY 3034767 8161191 TBMG_02746 Mycobacterium tuberculosis KZN 1435 sugar-binding lipoprotein lpqY YP_003032721.1 3033361 R 478434 CDS YP_003032722.1 253799721 8161192 complement(3034788..3035315) 1 NC_012943.1 hypothetical protein 3035315 8161192 TBMG_02747 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032722.1 3034788 R 478434 CDS YP_003032723.1 253799722 8161193 3035456..3036061 1 NC_012943.1 hypothetical protein 3036061 8161193 TBMG_02748 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032723.1 3035456 D 478434 CDS YP_003032724.1 253799723 8161194 3036123..3037430 1 NC_012943.1 hypothetical protein 3037430 8161194 TBMG_02749 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032724.1 3036123 D 478434 CDS YP_003032725.1 253799724 8161195 3037427..3037969 1 NC_012943.1 hypothetical protein 3037969 8161195 TBMG_02750 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032725.1 3037427 D 478434 CDS YP_003032726.1 253799725 8161196 3038094..3039329 1 NC_012943.1 hypothetical protein 3039329 8161196 TBMG_02751 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032726.1 3038094 D 478434 CDS YP_003032727.1 253799726 8161197 3039342..3040514 1 NC_012943.1 hypothetical protein 3040514 8161197 TBMG_02752 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032727.1 3039342 D 478434 CDS YP_003032728.1 253799727 8161198 complement(3040589..3040762) 1 NC_012943.1 hypothetical protein 3040762 8161198 TBMG_02753 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032728.1 3040589 R 478434 CDS YP_003032729.1 253799728 8161199 complement(3040814..3041371) 1 NC_012943.1 hypothetical protein 3041371 8161199 TBMG_02754 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032729.1 3040814 R 478434 CDS YP_003032730.1 253799729 8161200 3041466..3041999 1 NC_012943.1 hypothetical protein 3041999 8161200 TBMG_02755 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032730.1 3041466 D 478434 CDS YP_003032731.1 253799730 8161201 3041996..3043459 1 NC_012943.1 hypothetical protein 3043459 8161201 TBMG_02756 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032731.1 3041996 D 478434 CDS YP_003032732.1 253799731 8161202 3043570..3044400 1 NC_012943.1 hypothetical protein 3044400 8161202 TBMG_02757 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032732.1 3043570 D 478434 CDS YP_003032733.1 253799732 8161203 complement(3044433..3044828) 1 NC_012943.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 3044828 8161203 TBMG_02758 Mycobacterium tuberculosis KZN 1435 sec-independent translocase YP_003032733.1 3044433 R 478434 CDS YP_003032734.1 253799733 8161204 complement(3044830..3045918) 1 NC_012943.1 truncated CDS; heat shock protein HtrA 3045918 8161204 TBMG_02759 Mycobacterium tuberculosis KZN 1435 heat shock protein HtrA YP_003032734.1 3044830 R 478434 CDS YP_003032735.1 253799734 8161205 complement(3046485..3047144) 1 NC_012943.1 RNA polymerase sigma-70 factor 3047144 8161205 TBMG_02760 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma-70 factor YP_003032735.1 3046485 R 478434 CDS YP_003032736.1 253799735 8161206 complement(3047107..3047880) 1 NC_012943.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence; RNA polymerase sigma factor SigE 3047880 8161206 TBMG_02761 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigE YP_003032736.1 3047107 R 478434 CDS YP_003032737.1 253799736 8161207 3048047..3048790 1 NC_012943.1 methyltransferase 3048790 8161207 TBMG_02762 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032737.1 3048047 D 478434 CDS YP_003032738.1 253799737 8161208 3048932..3049570 1 NC_012943.1 transcriptional regulator 3049570 8161208 TBMG_02763 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032738.1 3048932 D 478434 CDS YP_003032739.1 253799738 8163795 3049560..3050495 1 NC_012943.1 tetronasin-transport ATP-binding protein ABC transporter 3050495 8163795 TBMG_02764 Mycobacterium tuberculosis KZN 1435 tetronasin-transport ATP-binding protein ABC transporter YP_003032739.1 3049560 D 478434 CDS YP_003032740.1 253799739 8163796 3050492..3052138 1 NC_012943.1 hypothetical protein 3052138 8163796 TBMG_02765 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032740.1 3050492 D 478434 CDS YP_003032741.1 253799740 8163797 3052147..3052821 1 NC_012943.1 hypothetical protein 3052821 8163797 TBMG_02766 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032741.1 3052147 D 478434 CDS YP_003032742.1 253799741 8163798 3052849..3054534 1 NC_012943.1 hypothetical protein 3054534 8163798 TBMG_02767 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032742.1 3052849 D 478434 CDS YP_003032743.1 253799742 8163799 3054668..3055000 1 NC_012943.1 PE family protein 3055000 8163799 TBMG_02768 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032743.1 3054668 D 478434 CDS YP_003032744.1 253799743 8163800 complement(3055243..3056457) 1 NC_012943.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3056457 glgC 8163800 glgC Mycobacterium tuberculosis KZN 1435 glucose-1-phosphate adenylyltransferase YP_003032744.1 3055243 R 478434 CDS YP_003032745.1 253799744 8163801 3056632..3057795 1 NC_012943.1 glycosyltransferase 3057795 8163801 TBMG_02770 Mycobacterium tuberculosis KZN 1435 glycosyltransferase YP_003032745.1 3056632 D 478434 CDS YP_003032746.1 253799745 8163802 complement(3057823..3058050) 1 NC_012943.1 hypothetical protein 3058050 8163802 TBMG_02771 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032746.1 3057823 R 478434 CDS YP_003032747.1 253799746 8163803 complement(3058157..3058771) 1 NC_012943.1 DNA-3-methyladenine glycosylase I tagA 3058771 8163803 TBMG_02772 Mycobacterium tuberculosis KZN 1435 DNA-3-methyladenine glycosylase I tagA YP_003032747.1 3058157 R 478434 CDS YP_003032748.1 253799747 8163804 complement(3058768..3059136) 1 NC_012943.1 hypothetical protein 3059136 8163804 TBMG_02773 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032748.1 3058768 R 478434 CDS YP_003032749.1 253799748 8163805 complement(3059175..3060149) 1 NC_012943.1 glucosyl-3-phosphoglycerate synthase 3060149 8163805 TBMG_02774 Mycobacterium tuberculosis KZN 1435 glucosyl-3-phosphoglycerate synthase YP_003032749.1 3059175 R 478434 CDS YP_003032750.1 253799749 8163806 complement(3060297..3061103) 1 NC_012943.1 truncated CDS; dihydropteroate synthase 2 folP2 3061103 8163806 TBMG_02775 Mycobacterium tuberculosis KZN 1435 dihydropteroate synthase 2 folP2 YP_003032750.1 3060297 R 478434 CDS YP_003032751.1 253799750 8163807 complement(3061169..3062962) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; long-chain-acyl-CoA synthetase 3062962 8163807 TBMG_02776 Mycobacterium tuberculosis KZN 1435 long-chain-acyl-CoA synthetase YP_003032751.1 3061169 R 478434 CDS YP_003032752.1 253799751 8163808 complement(3063012..3063575) 1 NC_012943.1 hypothetical protein 3063575 8163808 TBMG_02777 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032752.1 3063012 R 478434 CDS YP_003032753.1 253799752 8163809 3063688..3064578 1 NC_012943.1 hypothetical protein 3064578 8163809 TBMG_04073 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032753.1 3063688 D 478434 CDS YP_003032754.1 253799753 8162055 3064605..3065357 1 NC_012943.1 hypothetical protein 3065357 8162055 TBMG_04074 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032754.1 3064605 D 478434 CDS YP_003032755.1 253799754 8162056 3065388..3065972 1 NC_012943.1 hypothetical protein 3065972 8162056 TBMG_02779 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032755.1 3065388 D 478434 CDS YP_003032756.1 253799755 8162057 complement(3065969..3067033) 1 NC_012943.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 3067033 8162057 TBMG_02780 Mycobacterium tuberculosis KZN 1435 succinyl-diaminopimelate desuccinylase YP_003032756.1 3065969 R 478434 CDS YP_003032757.1 253799756 8162058 3067124..3068077 1 NC_012943.1 transferase 3068077 8162058 TBMG_02781 Mycobacterium tuberculosis KZN 1435 transferase YP_003032757.1 3067124 D 478434 CDS YP_003032758.1 253799757 8162059 complement(3068074..3069351) 1 NC_012943.1 membrane transporter 3069351 8162059 TBMG_02782 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003032758.1 3068074 R 478434 CDS YP_003032759.1 253799758 8162060 3069640..3070935 1 NC_012943.1 transposase 3070935 8162060 TBMG_02783 Mycobacterium tuberculosis KZN 1435 transposase YP_003032759.1 3069640 D 478434 CDS YP_003032760.1 253799759 8162061 complement(3071003..3071287) 1 NC_012943.1 esat-6 like protein esxL 3071287 8162061 TBMG_02784 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxL YP_003032760.1 3071003 R 478434 CDS YP_003032761.1 253799760 8162062 complement(3071338..3071634) 1 NC_012943.1 esat-6 like protein esxK 3071634 8162062 TBMG_02785 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxK YP_003032761.1 3071338 R 478434 CDS YP_003032762.1 253799761 8162063 complement(3071769..3072944) 1 NC_012943.1 PPE family protein 3072944 8162063 TBMG_02786 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032762.1 3071769 R 478434 CDS YP_003032763.1 253799762 8162064 complement(3072991..3073326) 1 NC_012943.1 PE family protein 3073326 8162064 TBMG_02787 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032763.1 3072991 R 478434 CDS YP_003032764.1 253799763 8162065 3073780..3075045 1 NC_012943.1 hypothetical protein 3075045 8162065 TBMG_02788 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032764.1 3073780 D 478434 CDS YP_003032765.1 253799764 8162066 complement(3075078..3076499) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3076499 8162066 TBMG_02789 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003032765.1 3075078 R 478434 CDS YP_003032766.1 253799765 8162067 complement(3076539..3077366) 1 NC_012943.1 hypothetical protein 3077366 8162067 TBMG_02790 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032766.1 3076539 R 478434 CDS YP_003032767.1 253799766 8162068 complement(3077448..3078362) 1 NC_012943.1 hypothetical protein 3078362 8162068 TBMG_02791 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032767.1 3077448 R 478434 CDS YP_003032768.1 253799767 8162069 complement(3078435..3079313) 1 NC_012943.1 hypothetical protein 3079313 8162069 TBMG_02792 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032768.1 3078435 R 478434 CDS YP_003032769.1 253799768 8162070 complement(3079329..3080201) 1 NC_012943.1 member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigI 3080201 sigI 8162070 sigI Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigI YP_003032769.1 3079329 R 478434 CDS YP_003032770.1 253799769 8162071 complement(3080283..3081272) 1 NC_012943.1 proline dehydrogenase 3081272 8162071 TBMG_02794 Mycobacterium tuberculosis KZN 1435 proline dehydrogenase YP_003032770.1 3080283 R 478434 CDS YP_003032771.1 253799770 8162072 complement(3081272..3082903) 1 NC_012943.1 pyrroline-5-carboxylate dehydrogenase rocA 3082903 8162072 TBMG_02795 Mycobacterium tuberculosis KZN 1435 pyrroline-5-carboxylate dehydrogenase rocA YP_003032771.1 3081272 R 478434 CDS YP_003032772.1 253799771 8162073 3083233..3084606 1 NC_012943.1 hypothetical protein 3084606 8162073 TBMG_02796 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032772.1 3083233 D 478434 CDS YP_003032773.1 253799772 8162074 3084783..3086519 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3086519 8162074 TBMG_02797 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003032773.1 3084783 D 478434 CDS YP_003032774.1 253799773 8162075 3086684..3087763 1 NC_012943.1 hypothetical protein 3087763 8162075 TBMG_02798 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032774.1 3086684 D 478434 CDS YP_003032775.1 253799774 8162076 complement(3087767..3090775) 1 NC_012943.1 transmembrane transporter mmpL10 3090775 8162076 TBMG_02799 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL10 YP_003032775.1 3087767 R 478434 CDS YP_003032776.1 253799775 8162077 complement(3090842..3092260) 1 NC_012943.1 polyketide synthase 3092260 8162077 TBMG_02800 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003032776.1 3090842 R 478434 CDS YP_003032777.1 253799776 8162078 complement(3092313..3098618) 1 NC_012943.1 polyketide beta-ketoacyl synthase 3098618 8162078 TBMG_02801 Mycobacterium tuberculosis KZN 1435 polyketide beta-ketoacyl synthase YP_003032777.1 3092313 R 478434 CDS YP_003032778.1 253799777 8162079 3098997..3101816 1 NC_012943.1 hypothetical protein 3101816 8162079 TBMG_02802 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032778.1 3098997 D 478434 CDS YP_003032779.1 253799778 8162080 complement(3101844..3102932) 1 NC_012943.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase 3102932 8162080 TBMG_02803 Mycobacterium tuberculosis KZN 1435 N-succinyldiaminopimelate aminotransferase YP_003032779.1 3101844 R 478434 CDS YP_003032780.1 253799779 8162081 complement(3102965..3103291) 1 NC_012943.1 ferredoxin fdxC 3103291 8162081 TBMG_02804 Mycobacterium tuberculosis KZN 1435 ferredoxin fdxC YP_003032780.1 3102965 R 478434 CDS YP_003032781.1 253799780 8162082 3103504..3104073 1 NC_012943.1 hypothetical protein 3104073 8162082 TBMG_02805 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032781.1 3103504 D 478434 CDS YP_003032782.1 253799781 8162083 3104070..3106094 1 NC_012943.1 NADPH dependent 2,4-dienoyl-CoA reductase fadH 3106094 8162083 TBMG_02806 Mycobacterium tuberculosis KZN 1435 NADPH dependent 2,4-dienoyl-CoA reductase fadH YP_003032782.1 3104070 D 478434 CDS YP_003032783.1 253799782 8162084 3106295..3106627 1 NC_012943.1 low molecular weight T-cell antigen 3106627 8162084 TBMG_02807 Mycobacterium tuberculosis KZN 1435 low molecular weight T-cell antigen YP_003032783.1 3106295 D 478434 CDS YP_003032784.1 253799783 8162085 complement(3106733..3109303) 1 NC_012943.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; FO synthase 3109303 fbiC 8162085 fbiC Mycobacterium tuberculosis KZN 1435 FO synthase YP_003032784.1 3106733 R 478434 CDS YP_003032785.1 253799784 8162086 3109553..3110479 1 NC_012943.1 PE family protein 3110479 8162086 TBMG_02809 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032785.1 3109553 D 478434 CDS YP_003032786.1 253799785 8160963 complement(3110487..3110927) 1 NC_012943.1 hypothetical protein 3110927 8160963 TBMG_02810 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032786.1 3110487 R 478434 CDS YP_003032787.1 253799786 8160964 complement(3111019..3111930) 1 NC_012943.1 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase mshB 3111930 8160964 TBMG_02811 Mycobacterium tuberculosis KZN 1435 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase mshB YP_003032787.1 3111019 R 478434 CDS YP_003032788.1 253799787 8160965 3112092..3112412 1 NC_012943.1 PE family protein 3112412 8160965 TBMG_02812 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032788.1 3112092 D 478434 CDS YP_003032789.1 253799788 8160966 3112430..3113470 1 NC_012943.1 PPE family protein 3113470 8160966 TBMG_02813 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032789.1 3112430 D 478434 CDS YP_003032790.1 253799789 8160967 3113542..3114147 1 NC_012943.1 transcriptional regulator 3114147 8160967 TBMG_02814 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032790.1 3113542 D 478434 CDS YP_003032791.1 253799790 8160968 complement(3114175..3116082) 1 NC_012943.1 hypothetical protein 3116082 8160968 TBMG_02815 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032791.1 3114175 R 478434 CDS YP_003032792.1 253799791 8160969 complement(3116180..3118066) 1 NC_012943.1 GTP-binding translation elongation factor typA 3118066 8160969 TBMG_02816 Mycobacterium tuberculosis KZN 1435 GTP-binding translation elongation factor typA YP_003032792.1 3116180 R 478434 CDS YP_003032793.1 253799792 8160970 complement(3118088..3118828) 1 NC_012943.1 respiratory nitrate reductase subunit gamma narI 3118828 8160970 TBMG_02817 Mycobacterium tuberculosis KZN 1435 respiratory nitrate reductase subunit gamma narI YP_003032793.1 3118088 R 478434 CDS YP_003032794.1 253799793 8160971 complement(3118831..3119496) 1 NC_012943.1 respiratory nitrate reductase subunit delta narJ 3119496 8160971 TBMG_02818 Mycobacterium tuberculosis KZN 1435 respiratory nitrate reductase subunit delta narJ YP_003032794.1 3118831 R 478434 CDS YP_003032795.1 253799794 8160972 complement(3119493..3121169) 1 NC_012943.1 respiratory nitrate reductase subunit beta narH 3121169 8160972 TBMG_02819 Mycobacterium tuberculosis KZN 1435 respiratory nitrate reductase subunit beta narH YP_003032795.1 3119493 R 478434 CDS YP_003032796.1 253799795 8160973 complement(3121208..3124906) 1 NC_012943.1 respiratory nitrate reductase subunit alpha narG 3124906 8160973 TBMG_02820 Mycobacterium tuberculosis KZN 1435 respiratory nitrate reductase subunit alpha narG YP_003032796.1 3121208 R 478434 CDS YP_003032797.1 253799796 8160974 complement(3125214..3125639) 1 NC_012943.1 mutator protein mutT 3125639 8160974 TBMG_02821 Mycobacterium tuberculosis KZN 1435 mutator protein mutT YP_003032797.1 3125214 R 478434 CDS YP_003032798.1 253799797 8160975 3125666..3125950 1 NC_012943.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 3125950 phhB 8160975 phhB Mycobacterium tuberculosis KZN 1435 pterin-4-alpha-carbinolamine dehydratase YP_003032798.1 3125666 D 478434 CDS YP_003032799.1 253799798 8160976 complement(3125947..3127242) 1 NC_012943.1 involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis; mannosyltransferase 3127242 pimE 8160976 pimE Mycobacterium tuberculosis KZN 1435 mannosyltransferase YP_003032799.1 3125947 R 478434 CDS YP_003032800.1 253799799 8160977 3127372..3128055 1 NC_012943.1 hypothetical protein 3128055 8160977 TBMG_02824 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032800.1 3127372 D 478434 CDS YP_003032801.1 253799800 8160978 3128135..3129178 1 NC_012943.1 hypothetical protein 3129178 8160978 TBMG_02825 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032801.1 3128135 D 478434 CDS YP_003032802.1 253799801 8160979 complement(3129341..3129928) 1 NC_012943.1 hypothetical protein 3129928 8160979 TBMG_02826 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032802.1 3129341 R 478434 CDS YP_003032803.1 253799802 8160980 complement(3130362..3130805) 1 NC_012943.1 hypothetical protein 3130805 8160980 TBMG_02827 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032803.1 3130362 R 478434 CDS YP_003032804.1 253799803 8160982 3130750..3131391 1 NC_012943.1 hypothetical protein 3131391 8160982 TBMG_02828 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032804.1 3130750 D 478434 CDS YP_003032805.1 253799804 8160981 3131388..3132236 1 NC_012943.1 O-methyltransferase omt 3132236 8160981 TBMG_02829 Mycobacterium tuberculosis KZN 1435 O-methyltransferase omt YP_003032805.1 3131388 D 478434 CDS YP_003032806.1 253799805 8160983 complement(3132214..3132579) 1 NC_012943.1 transcriptional regulator 3132579 8160983 TBMG_02830 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032806.1 3132214 R 478434 CDS YP_003032807.1 253799806 8160984 3132617..3133330 1 NC_012943.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 3133330 8160984 TBMG_02831 Mycobacterium tuberculosis KZN 1435 NAD-dependent deacetylase YP_003032807.1 3132617 D 478434 CDS YP_003032808.1 253799807 8160985 complement(3133414..3134277) 1 NC_012943.1 transposase 3134277 8160985 TBMG_02832 Mycobacterium tuberculosis KZN 1435 transposase YP_003032808.1 3133414 R 478434 CDS YP_003032809.1 253799808 8160986 3134436..3135935 1 NC_012943.1 hypothetical protein 3135935 8160986 TBMG_02833 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032809.1 3134436 D 478434 CDS YP_003032810.1 253799809 8160987 complement(3136261..3136593) 1 NC_012943.1 hypothetical protein 3136593 8160987 TBMG_02834 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032810.1 3136261 R 478434 CDS YP_003032811.1 253799810 8160988 complement(3136685..3137335) 1 NC_012943.1 hypothetical protein 3137335 8160988 TBMG_02835 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032811.1 3136685 R 478434 CDS YP_003032812.1 253799811 8160989 complement(3137468..3138880) 1 NC_012943.1 transmembrane transporter mmpL13b 3138880 8160989 TBMG_02836 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL13b YP_003032812.1 3137468 R 478434 CDS YP_003032813.1 253799812 8160990 complement(3138901..3139986) 1 NC_012943.1 transmembrane transporter mmpL13a 3139986 8160990 TBMG_02837 Mycobacterium tuberculosis KZN 1435 transmembrane transporter mmpL13a YP_003032813.1 3138901 R 478434 CDS YP_003032814.1 253799813 8160991 3140044..3140199 1 NC_012943.1 hypothetical protein 3140199 8160991 TBMG_04075 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032814.1 3140044 D 478434 CDS YP_003032815.1 253799814 8160992 complement(3140327..3141079) 1 NC_012943.1 short-chain type dehydrogenase/reductase 3141079 8160992 TBMG_02838 Mycobacterium tuberculosis KZN 1435 short-chain type dehydrogenase/reductase YP_003032815.1 3140327 R 478434 CDS YP_003032816.1 253799815 8160993 complement(3141091..3142278) 1 NC_012943.1 alpha-methylacyl-CoA racemase 3142278 8160993 TBMG_02839 Mycobacterium tuberculosis KZN 1435 alpha-methylacyl-CoA racemase YP_003032816.1 3141091 R 478434 CDS YP_003032817.1 253799816 8160995 3142277..3143083 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3143083 8160995 TBMG_02840 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003032817.1 3142277 D 478434 CDS YP_003032818.1 253799817 8160994 3143217..3144032 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3144032 8160994 TBMG_02841 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003032818.1 3143217 D 478434 CDS YP_003032819.1 253799818 8160996 complement(3144040..3144888) 1 NC_012943.1 hypothetical protein 3144888 8160996 TBMG_02842 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032819.1 3144040 R 478434 CDS YP_003032820.1 253799819 8160997 3145192..3145692 1 NC_012943.1 hypothetical protein 3145692 8160997 TBMG_02843 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032820.1 3145192 D 478434 CDS YP_003032821.1 253799820 8160998 3145689..3146705 1 NC_012943.1 oxidoreductase 3146705 8160998 TBMG_02844 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032821.1 3145689 D 478434 CDS YP_003032822.1 253799821 8160999 complement(3146739..3147143) 1 NC_012943.1 enoyl-CoA hydratase 3147143 8160999 TBMG_02845 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003032822.1 3146739 R 478434 CDS YP_003032823.1 253799822 8161000 complement(3147230..3147571) 1 NC_012943.1 enoyl-CoA hydratase 3147571 8161000 TBMG_02846 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003032823.1 3147230 R 478434 CDS YP_003032824.1 253799823 8161001 complement(3147621..3147863) 1 NC_012943.1 acetyl-CoA acetyltransferase 3147863 8161001 TBMG_02847 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003032824.1 3147621 R 478434 CDS YP_003032825.1 253799824 8161002 3147995..3149905 1 NC_012943.1 PPE family protein 3149905 8161002 TBMG_02848 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032825.1 3147995 D 478434 CDS YP_003032826.1 253799825 8161003 complement(3150019..3150255) 1 NC_012943.1 hypothetical protein 3150255 8161003 TBMG_04076 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032826.1 3150019 R 478434 CDS YP_003032827.1 253799826 8161004 3150801..3153110 1 NC_012943.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 3153110 8161004 TBMG_02849 Mycobacterium tuberculosis KZN 1435 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_003032827.1 3150801 D 478434 CDS YP_003032828.1 253799827 8161005 complement(3153122..3154852) 1 NC_012943.1 hypothetical protein 3154852 8161005 TBMG_02850 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032828.1 3153122 R 478434 CDS YP_003032829.1 253799828 8161006 complement(3154864..3156045) 1 NC_012943.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 3156045 8161006 TBMG_02851 Mycobacterium tuberculosis KZN 1435 citrate synthase YP_003032829.1 3154864 R 478434 CDS YP_003032830.1 253799829 8161007 complement(3156042..3157622) 1 NC_012943.1 hypothetical protein 3157622 8161007 TBMG_02852 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032830.1 3156042 R 478434 CDS YP_003032831.1 253799830 8161008 3157643..3159103 1 NC_012943.1 transcriptional regulator 3159103 8161008 TBMG_02853 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003032831.1 3157643 D 478434 CDS YP_003032832.1 253799831 8161009 3159205..3160560 1 NC_012943.1 hypothetical protein 3160560 8161009 TBMG_02854 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032832.1 3159205 D 478434 CDS YP_003032833.1 253799832 8161010 3160773..3162245 1 NC_012943.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 3162245 8161010 TBMG_02855 Mycobacterium tuberculosis KZN 1435 pyruvate phosphate dikinase YP_003032833.1 3160773 D 478434 CDS YP_003032834.1 253799833 8161011 3162242..3162847 1 NC_012943.1 hypothetical protein 3162847 8161011 TBMG_02856 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032834.1 3162242 D 478434 CDS YP_003032835.1 253799834 8161012 complement(3162851..3164095) 1 NC_012943.1 hypothetical protein 3164095 8161012 TBMG_02857 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032835.1 3162851 R 478434 CDS YP_003032836.1 253799835 8161013 complement(3164100..3165050) 1 NC_012943.1 epoxide hydrolase ephC 3165050 8161013 TBMG_02858 Mycobacterium tuberculosis KZN 1435 epoxide hydrolase ephC YP_003032836.1 3164100 R 478434 CDS YP_003032837.1 253799836 8161014 3165125..3166033 1 NC_012943.1 peroxidase bpoB 3166033 8161014 TBMG_02859 Mycobacterium tuberculosis KZN 1435 peroxidase bpoB YP_003032837.1 3165125 D 478434 CDS YP_003032838.1 253799837 8161015 complement(3166026..3167048) 1 NC_012943.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 3167048 8161015 TBMG_02860 Mycobacterium tuberculosis KZN 1435 6-phosphogluconate dehydrogenase YP_003032838.1 3166026 R 478434 CDS YP_003032839.1 253799838 8161016 complement(3167070..3168470) 1 NC_012943.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 3168470 8161016 TBMG_02861 Mycobacterium tuberculosis KZN 1435 glucose-6-phosphate 1-dehydrogenase YP_003032839.1 3167070 R 478434 CDS YP_003032840.1 253799839 8161017 3168673..3169167 1 NC_012943.1 hypothetical protein 3169167 8161017 TBMG_02862 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032840.1 3168673 D 478434 CDS YP_003032841.1 253799840 8161018 3169113..3169313 1 NC_012943.1 hypothetical protein 3169313 8161018 TBMG_02863 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032841.1 3169113 D 478434 CDS YP_003032842.1 253799841 8161019 3169346..3170206 1 NC_012943.1 hypothetical protein 3170206 8161019 TBMG_02864 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032842.1 3169346 D 478434 CDS YP_003032843.1 253799842 8161020 complement(3170221..3170544) 1 NC_012943.1 hypothetical protein 3170544 8161020 TBMG_02865 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032843.1 3170221 R 478434 CDS YP_003032844.1 253799843 8161021 3170787..3171062 1 NC_012943.1 hypothetical protein 3171062 8161021 TBMG_02866 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032844.1 3170787 D 478434 CDS YP_003032845.1 253799844 8161022 complement(3170989..3171174) 1 NC_012943.1 hypothetical protein 3171174 8161022 TBMG_02867 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032845.1 3170989 R 478434 CDS YP_003032846.1 253799845 8161023 complement(3171292..3171990) 1 NC_012943.1 hypothetical protein 3171990 8161023 TBMG_02868 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032846.1 3171292 R 478434 CDS YP_003032847.1 253799846 8161024 complement(3172193..3172567) 1 NC_012943.1 toxin 3172567 8161024 TBMG_02869 Mycobacterium tuberculosis KZN 1435 toxin YP_003032847.1 3172193 R 478434 CDS YP_003032848.1 253799847 8161025 complement(3172564..3172761) 1 NC_012943.1 antitoxin 3172761 8161025 TBMG_02870 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032848.1 3172564 R 478434 CDS YP_003032849.1 253799848 8161026 complement(3172849..3173922) 1 NC_012943.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 3173922 8161026 TBMG_02871 Mycobacterium tuberculosis KZN 1435 GTP-dependent nucleic acid-binding protein EngD YP_003032849.1 3172849 R 478434 CDS YP_003032850.1 253799849 8161027 3173985..3174968 1 NC_012943.1 hypothetical protein 3174968 8161027 TBMG_02872 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032850.1 3173985 D 478434 CDS YP_003032851.1 253799850 8161028 complement(3174985..3175992) 1 NC_012943.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3175992 ispH 8161028 ispH Mycobacterium tuberculosis KZN 1435 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_003032851.1 3174985 R 478434 CDS YP_003032852.1 253799851 8161029 3176082..3176720 1 NC_012943.1 hypothetical protein 3176720 8161029 TBMG_02874 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032852.1 3176082 D 478434 CDS YP_003032853.1 253799852 8161030 3176717..3177964 1 NC_012943.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 3177964 xseA 8161030 xseA Mycobacterium tuberculosis KZN 1435 exodeoxyribonuclease VII large subunit YP_003032853.1 3176717 D 478434 CDS YP_003032854.1 253799853 8161031 3177954..3178211 1 NC_012943.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 3178211 8161031 TBMG_02876 Mycobacterium tuberculosis KZN 1435 exodeoxyribonuclease VII small subunit YP_003032854.1 3177954 D 478434 CDS YP_003032855.1 253799854 8161032 3178221..3179333 1 NC_012943.1 cholesterol dehydrogenase 3179333 8161032 TBMG_02877 Mycobacterium tuberculosis KZN 1435 cholesterol dehydrogenase YP_003032855.1 3178221 D 478434 CDS YP_003032856.1 253799855 8161033 complement(3179351..3179761) 1 NC_012943.1 para-nitrobenzyl esterase 3179761 8161033 TBMG_02878 Mycobacterium tuberculosis KZN 1435 para-nitrobenzyl esterase YP_003032856.1 3179351 R 478434 CDS YP_003032857.1 253799856 8161034 complement(3179715..3180113) 1 NC_012943.1 para-nitrobenzyl esterase 3180113 8161034 TBMG_02879 Mycobacterium tuberculosis KZN 1435 para-nitrobenzyl esterase YP_003032857.1 3179715 R 478434 CDS YP_003032858.1 253799857 8161035 complement(3180187..3180876) 1 NC_012943.1 para-nitrobenzyl esterase 3180876 8161035 TBMG_02880 Mycobacterium tuberculosis KZN 1435 para-nitrobenzyl esterase YP_003032858.1 3180187 R 478434 CDS YP_003032859.1 253799858 8161036 3180886..3181206 1 NC_012943.1 antitoxin 3181206 8161036 TBMG_02881 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003032859.1 3180886 D 478434 CDS YP_003032860.1 253799859 8161037 3181206..3181517 1 NC_012943.1 toxin 3181517 8161037 TBMG_02882 Mycobacterium tuberculosis KZN 1435 toxin YP_003032860.1 3181206 D 478434 CDS YP_003032861.1 253799860 8161038 3181629..3182786 1 NC_012943.1 hypothetical protein 3182786 8161038 TBMG_02883 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032861.1 3181629 D 478434 CDS YP_003032862.1 253799861 8161039 complement(3182793..3183494) 1 NC_012943.1 hypothetical protein 3183494 8161039 TBMG_02884 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032862.1 3182793 R 478434 CDS YP_003032863.1 253799862 8161040 3183529..3184581 1 NC_012943.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 3184581 glpX 8161040 glpX Mycobacterium tuberculosis KZN 1435 fructose 1,6-bisphosphatase II YP_003032863.1 3183529 D 478434 CDS YP_003032864.1 253799863 8161041 3184612..3186036 1 NC_012943.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 3186036 fumC 8161041 fumC Mycobacterium tuberculosis KZN 1435 fumarate hydratase YP_003032864.1 3184612 D 478434 CDS YP_003032865.1 253799864 8161889 3186033..3186914 1 NC_012943.1 hypothetical protein 3186914 8161889 TBMG_02887 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032865.1 3186033 D 478434 CDS YP_003032866.1 253799865 8161890 complement(3186917..3187792) 1 NC_012943.1 glycosyl hydrolase 3187792 8161890 TBMG_02888 Mycobacterium tuberculosis KZN 1435 glycosyl hydrolase YP_003032866.1 3186917 R 478434 CDS YP_003032867.1 253799866 8161891 complement(3187879..3189180) 1 NC_012943.1 phosphate starvation-inducible protein phoH2 3189180 8161891 TBMG_02889 Mycobacterium tuberculosis KZN 1435 phosphate starvation-inducible protein phoH2 YP_003032867.1 3187879 R 478434 CDS YP_003032868.1 253799867 8161892 complement(3189391..3190218) 1 NC_012943.1 acyl-ACP desaturase 3190218 8161892 TBMG_02890 Mycobacterium tuberculosis KZN 1435 acyl-ACP desaturase YP_003032868.1 3189391 R 478434 CDS YP_003032869.1 253799868 8161893 complement(3190323..3191603) 1 NC_012943.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3191603 glyA 8161893 glyA Mycobacterium tuberculosis KZN 1435 serine hydroxymethyltransferase YP_003032869.1 3190323 R 478434 CDS YP_003032870.1 253799869 8161894 3191991..3192929 1 NC_012943.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3192929 8161894 TBMG_02892 Mycobacterium tuberculosis KZN 1435 pantothenate kinase YP_003032870.1 3191991 D 478434 CDS YP_003032871.1 253799870 8161895 complement(3193147..3195627) 1 NC_012943.1 PE-PGRS family protein 3195627 8161895 TBMG_04077 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032871.1 3193147 R 478434 CDS YP_003032872.1 253799871 8161896 complement(3196042..3196497) 1 NC_012943.1 cellulase celA2b 3196497 8161896 TBMG_02895 Mycobacterium tuberculosis KZN 1435 cellulase celA2b YP_003032872.1 3196042 R 478434 CDS YP_003032873.1 253799872 8161897 complement(3196475..3196579) 1 NC_012943.1 cellulase celA2a 3196579 8161897 TBMG_02896 Mycobacterium tuberculosis KZN 1435 cellulase celA2a YP_003032873.1 3196475 R 478434 CDS YP_003032874.1 253799873 8161898 complement(3196689..3196871) 1 NC_012943.1 hypothetical protein 3196871 8161898 TBMG_04078 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032874.1 3196689 R 478434 CDS YP_003032875.1 253799874 8161899 complement(3196965..3197270) 1 NC_012943.1 PE family protein 3197270 8161899 TBMG_02897 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032875.1 3196965 R 478434 CDS YP_003032876.1 253799875 8161900 complement(3197149..3197583) 1 NC_012943.1 PE family protein 3197583 8161900 TBMG_02898 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032876.1 3197149 R 478434 CDS YP_003032877.1 253799876 8161901 complement(3197736..3198056) 1 NC_012943.1 hypothetical protein 3198056 8161901 TBMG_02899 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032877.1 3197736 R 478434 CDS YP_003032878.1 253799877 8161902 complement(3198233..3200449) 1 NC_012943.1 PE-PGRS family protein 3200449 8161902 TBMG_02900 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032878.1 3198233 R 478434 CDS YP_003032879.1 253799878 8161903 complement(3200587..3201375) 1 NC_012943.1 short-chain (C15) Z-isoprenyl diphosphate synthase 3201375 8161903 TBMG_02901 Mycobacterium tuberculosis KZN 1435 short-chain (C15) Z-isoprenyl diphosphate synthase YP_003032879.1 3200587 R 478434 CDS YP_003032880.1 253799879 8161904 3201486..3202214 1 NC_012943.1 hemolysin 3202214 8161904 TBMG_02902 Mycobacterium tuberculosis KZN 1435 hemolysin YP_003032880.1 3201486 D 478434 CDS YP_003032881.1 253799880 8161905 complement(3202313..3204334) 1 NC_012943.1 hypothetical protein 3204334 8161905 TBMG_02903 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032881.1 3202313 R 478434 CDS YP_003032882.1 253799881 8161906 complement(3204321..3204587) 1 NC_012943.1 hypothetical protein 3204587 8161906 TBMG_02904 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032882.1 3204321 R 478434 CDS YP_003032883.1 253799882 8161907 complement(3204584..3205450) 1 NC_012943.1 mycothiol conjugate amidase mca 3205450 8161907 TBMG_02905 Mycobacterium tuberculosis KZN 1435 mycothiol conjugate amidase mca YP_003032883.1 3204584 R 478434 CDS YP_003032884.1 253799883 8161908 3205525..3205986 1 NC_012943.1 hypothetical protein 3205986 8161908 TBMG_02906 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032884.1 3205525 D 478434 CDS YP_003032885.1 253799884 8161909 3206172..3206666 1 NC_012943.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3206666 greA 8161909 greA Mycobacterium tuberculosis KZN 1435 transcription elongation factor GreA YP_003032885.1 3206172 D 478434 CDS YP_003032886.1 253799885 8161910 complement(3206737..3207903) 1 NC_012943.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 3207903 8161910 TBMG_02908 Mycobacterium tuberculosis KZN 1435 cystathionine gamma-synthase YP_003032886.1 3206737 R 478434 CDS YP_003032887.1 253799886 8161911 complement(3207935..3208657) 1 NC_012943.1 hypothetical protein 3208657 8161911 TBMG_02909 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032887.1 3207935 R 478434 CDS YP_003032888.1 253799887 8161912 complement(3208859..3210253) 1 NC_012943.1 cystathionine beta-synthase cbs 3210253 8161912 TBMG_02910 Mycobacterium tuberculosis KZN 1435 cystathionine beta-synthase cbs YP_003032888.1 3208859 R 478434 CDS YP_003032889.1 253799888 8161913 complement(3210310..3211386) 1 NC_012943.1 lipase lipU 3211386 8161913 TBMG_02911 Mycobacterium tuberculosis KZN 1435 lipase lipU YP_003032889.1 3210310 R 478434 CDS YP_003032890.1 253799889 8161914 3211594..3212544 1 NC_012943.1 hypothetical protein 3212544 8161914 TBMG_02912 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032890.1 3211594 D 478434 CDS YP_003032891.1 253799890 8161915 3212597..3213814 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3213814 8161915 TBMG_02913 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003032891.1 3212597 D 478434 CDS YP_003032892.1 253799891 8161916 complement(3214241..3214738) 1 NC_012943.1 truncated CDS; hypothetical protein 3214738 8161916 TBMG_02914 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032892.1 3214241 R 478434 CDS YP_003032893.1 253799892 8161917 complement(3214854..3215690) 1 NC_012943.1 hypothetical protein 3215690 8161917 TBMG_02915 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032893.1 3214854 R 478434 CDS YP_003032894.1 253799893 8161918 3215877..3216914 1 NC_012943.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 3216914 8161918 TBMG_02916 Mycobacterium tuberculosis KZN 1435 3-hydroxyisobutyryl-CoA hydrolase YP_003032894.1 3215877 D 478434 CDS YP_003032895.1 253799894 8161919 3216926..3217699 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3217699 8161919 TBMG_02917 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003032895.1 3216926 D 478434 CDS YP_003032896.1 253799895 8161920 3217696..3219459 1 NC_012943.1 hypothetical protein 3219459 8161920 TBMG_02918 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032896.1 3217696 D 478434 CDS YP_003032897.1 253799896 8161921 3219803..3221212 1 NC_012943.1 PE-PGRS family protein 3221212 8161921 TBMG_02919 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032897.1 3219803 D 478434 CDS YP_003032898.1 253799897 8161922 3221545..3223545 1 NC_012943.1 PE-PGRS family protein 3223545 8161922 TBMG_04079 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032898.1 3221545 D 478434 CDS YP_003032899.1 253799898 8161923 complement(3223573..3223968) 1 NC_012943.1 hypothetical protein 3223968 8161923 TBMG_02920 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032899.1 3223573 R 478434 CDS YP_003032900.1 253799899 8161924 complement(3223965..3224531) 1 NC_012943.1 hypothetical protein 3224531 8161924 TBMG_02921 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032900.1 3223965 R 478434 CDS YP_003032901.1 253799900 8161925 3224643..3225062 1 NC_012943.1 hypothetical protein 3225062 8161925 TBMG_02922 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032901.1 3224643 D 478434 CDS YP_003032902.1 253799901 8161926 3225143..3226225 1 NC_012943.1 hypothetical protein 3226225 8161926 TBMG_02923 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032902.1 3225143 D 478434 CDS YP_003032903.1 253799902 8161927 complement(3226226..3227110) 1 NC_012943.1 hypothetical protein 3227110 8161927 TBMG_02924 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032903.1 3226226 R 478434 CDS YP_003032904.1 253799903 8161928 complement(3227088..3227951) 1 NC_012943.1 hypothetical protein 3227951 8161928 TBMG_02925 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032904.1 3227088 R 478434 CDS YP_003032905.1 253799904 8161929 complement(3227985..3228458) 1 NC_012943.1 hypothetical protein 3228458 8161929 TBMG_02926 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032905.1 3227985 R 478434 CDS YP_003032906.1 253799905 8161930 complement(3228511..3229575) 1 NC_012943.1 hypothetical protein 3229575 8161930 TBMG_02927 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032906.1 3228511 R 478434 CDS YP_003032907.1 253799906 8161931 complement(3229651..3231282) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 3231282 8161931 TBMG_02928 Mycobacterium tuberculosis KZN 1435 long-chain-fatty-acid--CoA ligase YP_003032907.1 3229651 R 478434 CDS YP_003032908.1 253799907 8161932 complement(3231389..3232621) 1 NC_012943.1 hypothetical protein 3232621 8161932 TBMG_02929 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032908.1 3231389 R 478434 CDS YP_003032909.1 253799908 8161933 3233150..3233362 1 NC_012943.1 hypothetical protein 3233362 8161933 TBMG_04080 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032909.1 3233150 D 478434 CDS YP_003032910.1 253799909 8161934 complement(3233574..3234338) 1 NC_012943.1 hypothetical protein 3234338 8161934 TBMG_02930 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032910.1 3233574 R 478434 CDS YP_003032911.1 253799910 8161936 complement(3234593..3234727) 1 NC_012943.1 integrase 3234727 8161936 TBMG_02931 Mycobacterium tuberculosis KZN 1435 integrase YP_003032911.1 3234593 R 478434 CDS YP_003032912.1 253799911 8161937 complement(3234724..3235080) 1 NC_012943.1 integrase 3235080 8161937 TBMG_02932 Mycobacterium tuberculosis KZN 1435 integrase YP_003032912.1 3234724 R 478434 CDS YP_003032913.1 253799912 8161938 complement(3235062..3235400) 1 NC_012943.1 hypothetical protein 3235400 8161938 TBMG_02933 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032913.1 3235062 R 478434 CDS YP_003032914.1 253799913 8161939 3235680..3235955 1 NC_012943.1 hypothetical protein 3235955 8161939 TBMG_04081 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032914.1 3235680 D 478434 CDS YP_003032915.1 253799914 8161940 complement(3235854..3236243) 1 NC_012943.1 hypothetical protein 3236243 8161940 TBMG_04082 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032915.1 3235854 R 478434 CDS YP_003032916.1 253799915 8161941 3236345..3236971 1 NC_012943.1 hypothetical protein 3236971 8161941 TBMG_02936 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032916.1 3236345 D 478434 CDS YP_003032917.1 253799916 8161942 3237266..3238021 1 NC_012943.1 hypothetical protein 3238021 8161942 TBMG_02937 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032917.1 3237266 D 478434 CDS YP_003032918.1 253799917 8161943 complement(3238180..3239088) 1 NC_012943.1 oxidoreductase 3239088 8161943 TBMG_02938 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003032918.1 3238180 R 478434 CDS YP_003032919.1 253799918 8161944 complement(3239134..3239580) 1 NC_012943.1 transcriptional repressor 3239580 8161944 TBMG_02939 Mycobacterium tuberculosis KZN 1435 transcriptional repressor YP_003032919.1 3239134 R 478434 CDS YP_003032920.1 253799919 8161945 3239813..3240928 1 NC_012943.1 hypothetical protein 3240928 8161945 TBMG_02940 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032920.1 3239813 D 478434 CDS YP_003032921.1 253799920 8161946 complement(3241296..3242606) 1 NC_012943.1 transposase 3242606 8161946 TBMG_02941 Mycobacterium tuberculosis KZN 1435 transposase YP_003032921.1 3241296 R 478434 CDS YP_003032922.1 253799921 8161948 3242543..3243331 1 NC_012943.1 hypothetical protein 3243331 8161948 TBMG_02942 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032922.1 3242543 D 478434 CDS YP_003032923.1 253799922 8161947 complement(3243413..3244294) 1 NC_012943.1 hypothetical protein 3244294 8161947 TBMG_02943 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032923.1 3243413 R 478434 CDS YP_003032924.1 253799923 8161949 complement(3244291..3244914) 1 NC_012943.1 hypothetical protein 3244914 8161949 TBMG_02944 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032924.1 3244291 R 478434 CDS YP_003032925.1 253799924 8161950 3245155..3246186 1 NC_012943.1 hypothetical protein 3246186 8161950 TBMG_02945 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032925.1 3245155 D 478434 CDS YP_003032926.1 253799925 8161951 3246469..3246876 1 NC_012943.1 transposase 3246876 8161951 TBMG_04083 Mycobacterium tuberculosis KZN 1435 transposase YP_003032926.1 3246469 D 478434 CDS YP_003032927.1 253799926 8161952 3246959..3247396 1 NC_012943.1 transposase 3247396 8161952 TBMG_04084 Mycobacterium tuberculosis KZN 1435 transposase YP_003032927.1 3246959 D 478434 CDS YP_003032928.1 253799927 8161953 3247532..3247804 1 NC_012943.1 hypothetical protein 3247804 8161953 TBMG_04085 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032928.1 3247532 D 478434 CDS YP_003032929.1 253799928 8161954 3248592..3249419 1 NC_012943.1 PE family protein 3249419 8161954 TBMG_02947 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003032929.1 3248592 D 478434 CDS YP_003032930.1 253799929 8161955 3249496..3250671 1 NC_012943.1 PPE family protein 3250671 8161955 TBMG_02948 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003032930.1 3249496 D 478434 CDS YP_003032931.1 253799930 8161956 3250817..3251113 1 NC_012943.1 esat-6 like protein esxJ 3251113 8161956 TBMG_02949 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxJ YP_003032931.1 3250817 D 478434 CDS YP_003032932.1 253799931 8161957 3251140..3251424 1 NC_012943.1 esat-6 like protein esxI 3251424 8161957 TBMG_02950 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxI YP_003032932.1 3251140 D 478434 CDS YP_003032933.1 253799932 8161958 3251535..3251873 1 NC_012943.1 transposase 3251873 8161958 TBMG_02951 Mycobacterium tuberculosis KZN 1435 transposase YP_003032933.1 3251535 D 478434 CDS YP_003032934.1 253799933 8161959 3251907..3252593 1 NC_012943.1 transposase 3252593 8161959 TBMG_02952 Mycobacterium tuberculosis KZN 1435 transposase YP_003032934.1 3251907 D 478434 CDS YP_003032935.1 253799934 8161960 3252556..3253050 1 NC_012943.1 transposase 3253050 8161960 TBMG_02953 Mycobacterium tuberculosis KZN 1435 transposase YP_003032935.1 3252556 D 478434 CDS YP_003032936.1 253799935 8161961 3253232..3254005 1 NC_012943.1 two component system transcriptional regulator trcR 3254005 8161961 TBMG_02954 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator trcR YP_003032936.1 3253232 D 478434 CDS YP_003032937.1 253799936 8161962 3254013..3254918 1 NC_012943.1 two component system sensor histidine kinase trcS 3254918 8161962 TBMG_04086 Mycobacterium tuberculosis KZN 1435 two component system sensor histidine kinase trcS YP_003032937.1 3254013 D 478434 CDS YP_003032938.1 253799937 8161963 3254888..3255541 1 NC_012943.1 two component system sensor histidine kinase trcS 3255541 8161963 TBMG_04087 Mycobacterium tuberculosis KZN 1435 two component system sensor histidine kinase trcS YP_003032938.1 3254888 D 478434 CDS YP_003032939.1 253799938 8161964 complement(3255545..3256114) 1 NC_012943.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 3256114 8161964 TBMG_02956 Mycobacterium tuberculosis KZN 1435 potassium-transporting ATPase subunit C YP_003032939.1 3255545 R 478434 CDS YP_003032940.1 253799939 8161965 complement(3256114..3258243) 1 NC_012943.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 3258243 8161965 TBMG_02957 Mycobacterium tuberculosis KZN 1435 potassium-transporting ATPase subunit B YP_003032940.1 3256114 R 478434 CDS YP_003032941.1 253799940 8161966 complement(3258240..3259955) 1 NC_012943.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 3259955 8161966 TBMG_02958 Mycobacterium tuberculosis KZN 1435 potassium-transporting ATPase subunit A YP_003032941.1 3258240 R 478434 CDS YP_003032942.1 253799941 8161967 complement(3259955..3260047) 1 NC_012943.1 hypothetical protein 3260047 8161967 TBMG_04088 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032942.1 3259955 R 478434 CDS YP_003032943.1 253799942 8161968 3260281..3262863 1 NC_012943.1 two component system sensor protein kdpD 3262863 8161968 TBMG_02959 Mycobacterium tuberculosis KZN 1435 two component system sensor protein kdpD YP_003032943.1 3260281 D 478434 CDS YP_003032944.1 253799943 8161969 3262860..3263540 1 NC_012943.1 transcriptional regulator kdpE 3263540 8161969 TBMG_02960 Mycobacterium tuberculosis KZN 1435 transcriptional regulator kdpE YP_003032944.1 3262860 D 478434 CDS YP_003032945.1 253799944 8161209 complement(3263989..3264948) 1 NC_012943.1 hypothetical protein 3264948 8161209 TBMG_02961 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032945.1 3263989 R 478434 CDS YP_003032946.1 253799945 8161210 complement(3264939..3265430) 1 NC_012943.1 hypothetical protein 3265430 8161210 TBMG_02962 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032946.1 3264939 R 478434 CDS YP_003032947.1 253799946 8161211 complement(3265423..3266109) 1 NC_012943.1 hypothetical protein 3266109 8161211 TBMG_02963 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032947.1 3265423 R 478434 CDS YP_003032948.1 253799947 8164080 complement(3266114..3267403) 1 NC_012943.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3267403 eno 8164080 eno Mycobacterium tuberculosis KZN 1435 phosphopyruvate hydratase YP_003032948.1 3266114 R 478434 CDS YP_003032949.1 253799948 8164081 complement(3267500..3268231) 1 NC_012943.1 hypothetical protein 3268231 8164081 TBMG_02965 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032949.1 3267500 R 478434 CDS YP_003032950.1 253799949 8164082 complement(3268319..3269296) 1 NC_012943.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3269296 8164082 TBMG_02966 Mycobacterium tuberculosis KZN 1435 nucleoside triphosphate pyrophosphohydrolase YP_003032950.1 3268319 R 478434 CDS YP_003032951.1 253799950 8164083 complement(3269296..3273000) 1 NC_012943.1 transcription-repair coupling factor mfd 3273000 8164083 TBMG_02967 Mycobacterium tuberculosis KZN 1435 transcription-repair coupling factor mfd YP_003032951.1 3269296 R 478434 CDS YP_003032952.1 253799951 8164084 complement(3273059..3273667) 1 NC_012943.1 TetR family transcriptional regulator 3273667 8164084 TBMG_02968 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003032952.1 3273059 R 478434 CDS YP_003032953.1 253799952 8164086 3273907..3275394 1 NC_012943.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 3275394 glmU 8164086 glmU Mycobacterium tuberculosis KZN 1435 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_003032953.1 3273907 D 478434 CDS YP_003032954.1 253799953 8164087 3275486..3276466 1 NC_012943.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 3276466 8164087 TBMG_02970 Mycobacterium tuberculosis KZN 1435 ribose-phosphate pyrophosphokinase YP_003032954.1 3275486 D 478434 CDS YP_003032955.1 253799954 8164088 3276502..3277182 1 NC_012943.1 hypothetical protein 3277182 8164088 TBMG_02971 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032955.1 3276502 D 478434 CDS YP_003032956.1 253799955 8164089 3277399..3278046 1 NC_012943.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 3278046 8164089 TBMG_02972 Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L25 YP_003032956.1 3277399 D 478434 CDS YP_003032957.1 253799956 8164090 3278059..3278634 1 NC_012943.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 3278634 8164090 TBMG_02973 Mycobacterium tuberculosis KZN 1435 peptidyl-tRNA hydrolase YP_003032957.1 3278059 D 478434 CDS YP_003032958.1 253799957 8164091 complement(3278708..3280342) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 3280342 8164091 TBMG_02974 Mycobacterium tuberculosis KZN 1435 long-chain-fatty-acid--CoA ligase YP_003032958.1 3278708 R 478434 CDS YP_003032959.1 253799958 8164092 complement(3280546..3280839) 1 NC_012943.1 hypothetical protein 3280839 8164092 TBMG_02975 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032959.1 3280546 R 478434 CDS YP_003032960.1 253799959 8164093 complement(3280856..3281776) 1 NC_012943.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 3281776 8164093 TBMG_02976 Mycobacterium tuberculosis KZN 1435 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_003032960.1 3280856 R 478434 CDS YP_003032961.1 253799960 8164094 complement(3281862..3282833) 1 NC_012943.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 3282833 ksgA 8164094 ksgA Mycobacterium tuberculosis KZN 1435 dimethyladenosine transferase YP_003032961.1 3281862 R 478434 CDS YP_003032962.1 253799961 8164095 complement(3282788..3283876) 1 NC_012943.1 resuscitation-promoting factor rpfB 3283876 8164095 TBMG_02978 Mycobacterium tuberculosis KZN 1435 resuscitation-promoting factor rpfB YP_003032962.1 3282788 R 478434 CDS YP_003032963.1 253799962 8164096 complement(3284084..3284878) 1 NC_012943.1 deoxyribonuclease tatD 3284878 8164096 TBMG_02979 Mycobacterium tuberculosis KZN 1435 deoxyribonuclease tatD YP_003032963.1 3284084 R 478434 CDS YP_003032964.1 253799963 8164097 3284964..3286523 1 NC_012943.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 3286523 8164097 TBMG_02980 Mycobacterium tuberculosis KZN 1435 methionyl-tRNA synthetase YP_003032964.1 3284964 D 478434 CDS YP_003032965.1 253799964 8164098 complement(3286550..3288253) 1 NC_012943.1 hypothetical protein 3288253 8164098 TBMG_02981 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032965.1 3286550 R 478434 CDS YP_003032966.1 253799965 8164099 3288369..3289745 1 NC_012943.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase component I 3289745 8164099 TBMG_02982 Mycobacterium tuberculosis KZN 1435 aminodeoxychorismate synthase component I YP_003032966.1 3288369 D 478434 CDS YP_003032967.1 253799966 8164100 3289780..3291078 1 NC_012943.1 hypothetical protein 3291078 8164100 TBMG_02983 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032967.1 3289780 D 478434 CDS YP_003032968.1 253799967 8164101 complement(3291088..3291945) 1 NC_012943.1 hypothetical protein 3291945 8164101 TBMG_02984 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032968.1 3291088 R 478434 CDS YP_003032969.1 253799968 8164102 3291971..3293539 1 NC_012943.1 hypothetical protein 3293539 8164102 TBMG_02985 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032969.1 3291971 D 478434 CDS YP_003032970.1 253799969 8164103 complement(3293574..3294782) 1 NC_012943.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 3294782 8164103 TBMG_02986 Mycobacterium tuberculosis KZN 1435 arginine deiminase YP_003032970.1 3293574 R 478434 CDS YP_003032971.1 253799970 8164104 3294819..3295436 1 NC_012943.1 hypothetical protein 3295436 8164104 TBMG_02987 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032971.1 3294819 D 478434 CDS YP_003032972.1 253799971 8164105 complement(3295442..3296200) 1 NC_012943.1 hypothetical protein 3296200 8164105 TBMG_02988 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032972.1 3295442 R 478434 CDS YP_003032973.1 253799972 8164106 complement(3296218..3297219) 1 NC_012943.1 hypothetical protein 3297219 8164106 TBMG_02989 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032973.1 3296218 R 478434 CDS YP_003032974.1 253799973 8164107 3297261..3297581 1 NC_012943.1 methyltransferase 3297581 8164107 TBMG_04089 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032974.1 3297261 D 478434 CDS YP_003032975.1 253799974 8164108 3297585..3297794 1 NC_012943.1 methyltransferase 3297794 8164108 TBMG_02991 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003032975.1 3297585 D 478434 CDS YP_003032976.1 253799975 8164109 complement(3297855..3298106) 1 NC_012943.1 hypothetical protein 3298106 8164109 TBMG_02992 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032976.1 3297855 R 478434 CDS YP_003032977.1 253799976 8164111 complement(3298507..3299682) 1 NC_012943.1 hypothetical protein 3299682 8164111 TBMG_02993 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032977.1 3298507 R 478434 CDS YP_003032978.1 253799977 8164112 complement(3299744..3300397) 1 NC_012943.1 ribosomal-protein-alanine acetyltransferase rimJ 3300397 8164112 TBMG_02994 Mycobacterium tuberculosis KZN 1435 ribosomal-protein-alanine acetyltransferase rimJ YP_003032978.1 3299744 R 478434 CDS YP_003032979.1 253799978 8164113 complement(3300418..3301698) 1 NC_012943.1 molybdopterin biosynthesis protein moeA1 3301698 8164113 TBMG_02995 Mycobacterium tuberculosis KZN 1435 molybdopterin biosynthesis protein moeA1 YP_003032979.1 3300418 R 478434 CDS YP_003032980.1 253799979 8164114 complement(3301775..3302695) 1 NC_012943.1 UTP-glucose-1-phosphate uridylyltransferase 3302695 8164114 TBMG_02996 Mycobacterium tuberculosis KZN 1435 UTP-glucose-1-phosphate uridylyltransferase YP_003032980.1 3301775 R 478434 CDS YP_003032981.1 253799980 8164115 3302718..3303389 1 NC_012943.1 hypothetical protein 3303389 8164115 TBMG_02997 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032981.1 3302718 D 478434 CDS YP_003032982.1 253799981 8164116 3303442..3303795 1 NC_012943.1 hypothetical protein 3303795 8164116 TBMG_02998 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032982.1 3303442 D 478434 CDS YP_003032983.1 253799982 8164117 3303868..3304524 1 NC_012943.1 hypothetical protein 3304524 8164117 TBMG_02999 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032983.1 3303868 D 478434 CDS YP_003032984.1 253799983 8164118 3304585..3305562 1 NC_012943.1 polyprenyl synthetase 3305562 8164118 TBMG_03000 Mycobacterium tuberculosis KZN 1435 polyprenyl synthetase YP_003032984.1 3304585 D 478434 CDS YP_003032985.1 253799984 8164119 complement(3305691..3306851) 1 NC_012943.1 hypothetical protein 3306851 8164119 TBMG_03001 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032985.1 3305691 R 478434 CDS YP_003032986.1 253799985 8164120 complement(3306858..3309425) 1 NC_012943.1 hypothetical protein 3309425 8164120 TBMG_03002 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032986.1 3306858 R 478434 CDS YP_003032987.1 253799986 8164121 complement(3309418..3310164) 1 NC_012943.1 adhesion component transport ATP-binding protein ABC transporter 3310164 8164121 TBMG_03003 Mycobacterium tuberculosis KZN 1435 adhesion component transport ATP-binding protein ABC transporter YP_003032987.1 3309418 R 478434 CDS YP_003032988.1 253799987 8164122 3310487..3310942 1 NC_012943.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3310942 mscL 8164122 mscL Mycobacterium tuberculosis KZN 1435 large-conductance mechanosensitive channel YP_003032988.1 3310487 D 478434 CDS YP_003032989.1 253799988 8164123 complement(3310962..3311507) 1 NC_012943.1 pterin-4-alpha-carbinolamine dehydratase 3311507 8164123 TBMG_03005 Mycobacterium tuberculosis KZN 1435 pterin-4-alpha-carbinolamine dehydratase YP_003032989.1 3310962 R 478434 CDS YP_003032990.1 253799989 8164124 complement(3311507..3312901) 1 NC_012943.1 serine protease pepD 3312901 8164124 TBMG_03006 Mycobacterium tuberculosis KZN 1435 serine protease pepD YP_003032990.1 3311507 R 478434 CDS YP_003032991.1 253799990 8164125 complement(3312945..3314459) 1 NC_012943.1 two component system sensor kinase mprB 3314459 8164125 TBMG_03007 Mycobacterium tuberculosis KZN 1435 two component system sensor kinase mprB YP_003032991.1 3312945 R 478434 CDS YP_003032992.1 253799991 8164126 complement(3314459..3315151) 1 NC_012943.1 persistence regulator MprA 3315151 8164126 TBMG_03008 Mycobacterium tuberculosis KZN 1435 persistence regulator MprA YP_003032992.1 3314459 R 478434 CDS YP_003032993.1 253799992 8164127 3315516..3316889 1 NC_012943.1 PE-PGRS family protein 3316889 8164127 TBMG_03009 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032993.1 3315516 D 478434 CDS YP_003032994.2 484868057 8164128 complement(3316908..3317081) 1 NC_012943.1 50S ribosomal protein L32 3317081 8164128 TBMG_03010 Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L32 YP_003032994.2 3316908 R 478434 CDS YP_003032995.1 253799994 8164129 3317611..3318618 1 NC_012943.1 PE-PGRS family protein 3318618 8164129 TBMG_03011 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032995.1 3317611 D 478434 CDS YP_003032996.1 253799995 8164130 complement(3318835..3321636) 1 NC_012943.1 PE-PGRS family protein 3321636 8164130 TBMG_04090 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003032996.1 3318835 R 478434 CDS YP_003032997.1 253799996 8164131 3321804..3323486 1 NC_012943.1 hypothetical protein 3323486 8164131 TBMG_03012 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003032997.1 3321804 D 478434 CDS YP_003032998.1 253799997 8164132 3323483..3324631 1 NC_012943.1 acyl-CoA dehydrogenase 3324631 8164132 TBMG_03013 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003032998.1 3323483 D 478434 CDS YP_003032999.1 253799998 8164133 3324628..3326223 1 NC_012943.1 acetyl-/propionyl-CoA carboxylase beta subunit accD2 3326223 8164133 TBMG_03014 Mycobacterium tuberculosis KZN 1435 acetyl-/propionyl-CoA carboxylase beta subunit accD2 YP_003032999.1 3324628 D 478434 CDS YP_003033000.1 253799999 8164134 3326229..3328232 1 NC_012943.1 acetyl-/propionyl-CoA carboxylase alpha subunit accA2 3328232 8164134 TBMG_03015 Mycobacterium tuberculosis KZN 1435 acetyl-/propionyl-CoA carboxylase alpha subunit accA2 YP_003033000.1 3326229 D 478434 CDS YP_003033001.1 253800000 8164135 3328229..3329395 1 NC_012943.1 acyl-CoA dehydrogenase 3329395 8164135 TBMG_03016 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033001.1 3328229 D 478434 CDS YP_003033002.1 253800001 8164136 3329395..3330204 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3330204 8164136 TBMG_03017 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003033002.1 3329395 D 478434 CDS YP_003033003.1 253800002 8164137 complement(3330295..3330927) 1 NC_012943.1 hypothetical protein 3330927 8164137 TBMG_03018 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033003.1 3330295 R 478434 CDS YP_003033004.1 253800003 8164138 complement(3330924..3333302) 1 NC_012943.1 metal cation transporting P-type ATPase ctpV 3333302 8164138 TBMG_03019 Mycobacterium tuberculosis KZN 1435 metal cation transporting P-type ATPase ctpV YP_003033004.1 3330924 R 478434 CDS YP_003033005.1 253800004 8164139 complement(3333292..3333588) 1 NC_012943.1 hypothetical protein 3333588 8164139 TBMG_03020 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033005.1 3333292 R 478434 CDS YP_003033006.1 253800005 8164140 complement(3333645..3334004) 1 NC_012943.1 hypothetical protein 3334004 8164140 TBMG_03021 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033006.1 3333645 R 478434 CDS YP_003033007.1 253800006 8164141 3334054..3334746 1 NC_012943.1 hypothetical protein 3334746 8164141 TBMG_03022 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033007.1 3334054 D 478434 CDS YP_003033008.1 253800007 8164142 3334782..3335201 1 NC_012943.1 hypothetical protein 3335201 8164142 TBMG_03023 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033008.1 3334782 D 478434 CDS YP_003033009.1 253800008 8164143 3335301..3335783 1 NC_012943.1 hypothetical protein 3335783 8164143 TBMG_03024 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033009.1 3335301 D 478434 CDS YP_003033010.1 253800009 8164144 3335720..3336682 1 NC_012943.1 hypothetical protein 3336682 8164144 TBMG_03025 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033010.1 3335720 D 478434 CDS YP_003033011.1 253800010 8164145 3336865..3337539 1 NC_012943.1 hypothetical protein 3337539 8164145 TBMG_03026 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033011.1 3336865 D 478434 CDS YP_003033012.1 253800011 8164146 complement(3337558..3337905) 1 NC_012943.1 hypothetical protein 3337905 8164146 TBMG_03027 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033012.1 3337558 R 478434 CDS YP_003033013.1 253800012 8164147 complement(3338051..3338434) 1 NC_012943.1 toxin 3338434 8164147 TBMG_03028 Mycobacterium tuberculosis KZN 1435 toxin YP_003033013.1 3338051 R 478434 CDS YP_003033014.1 253800013 8164148 complement(3338431..3338652) 1 NC_012943.1 antitoxin 3338652 8164148 TBMG_03029 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003033014.1 3338431 R 478434 CDS YP_003033015.1 253800014 8164149 complement(3338706..3340724) 1 NC_012943.1 hypothetical protein 3340724 8164149 TBMG_03030 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033015.1 3338706 R 478434 CDS YP_003033016.1 253800015 8164150 complement(3340717..3342096) 1 NC_012943.1 magnesium chelatase 3342096 8164150 TBMG_03031 Mycobacterium tuberculosis KZN 1435 magnesium chelatase YP_003033016.1 3340717 R 478434 CDS YP_003033017.1 253800016 8164151 complement(3342203..3343774) 1 NC_012943.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3343774 purH 8164151 purH Mycobacterium tuberculosis KZN 1435 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_003033017.1 3342203 R 478434 CDS YP_003033018.1 253800017 8164152 complement(3343771..3344418) 1 NC_012943.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 3344418 purN 8164152 purN Mycobacterium tuberculosis KZN 1435 phosphoribosylglycinamide formyltransferase YP_003033018.1 3343771 R 478434 CDS YP_003033019.1 253800018 8164153 complement(3344534..3345901) 1 NC_012943.1 hypothetical protein 3345901 8164153 TBMG_03034 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033019.1 3344534 R 478434 CDS YP_003033020.1 253800019 8164154 complement(3345941..3346852) 1 NC_012943.1 hypothetical protein 3346852 8164154 TBMG_03035 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033020.1 3345941 R 478434 CDS YP_003033021.1 253800020 8164155 3346993..3347865 1 NC_012943.1 oxidoreductase 3347865 8164155 TBMG_03036 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033021.1 3346993 D 478434 CDS YP_003033022.1 253800021 8164156 complement(3347928..3348839) 1 NC_012943.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 3348839 8164156 TBMG_04091 Mycobacterium tuberculosis KZN 1435 succinyl-CoA synthetase subunit alpha YP_003033022.1 3347928 R 478434 CDS YP_003033023.1 253800022 8164157 complement(3348852..3350015) 1 NC_012943.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 3350015 sucC 8164157 sucC Mycobacterium tuberculosis KZN 1435 succinyl-CoA synthetase subunit beta YP_003033023.1 3348852 R 478434 CDS YP_003033024.1 253800023 8164158 3350758..3351321 1 NC_012943.1 truncated CDS; hypothetical protein 3351321 8164158 TBMG_03038 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033024.1 3350758 D 478434 CDS YP_003033025.1 253800024 8160822 complement(3351402..3353717) 1 NC_012943.1 ATP-dependent DNA helicase II uvrD1 3353717 8160822 TBMG_03039 Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA helicase II uvrD1 YP_003033025.1 3351402 R 478434 CDS YP_003033026.1 253800025 8160823 3354014..3354331 1 NC_012943.1 hypothetical protein 3354331 8160823 TBMG_03040 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033026.1 3354014 D 478434 CDS YP_003033027.1 253800026 8160824 3354447..3354677 1 NC_012943.1 mycolyl transferase 3354677 8160824 TBMG_03041 Mycobacterium tuberculosis KZN 1435 mycolyl transferase YP_003033027.1 3354447 D 478434 CDS YP_003033028.1 253800027 8163810 3354907..3355191 1 NC_012943.1 hypothetical protein 3355191 8163810 TBMG_03042 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033028.1 3354907 D 478434 CDS YP_003033029.1 253800028 8161403 3355292..3356953 1 NC_012943.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 3356953 pgi 8161403 pgi Mycobacterium tuberculosis KZN 1435 glucose-6-phosphate isomerase YP_003033029.1 3355292 D 478434 CDS YP_003033030.1 253800029 8161404 complement(3356969..3357730) 1 NC_012943.1 short chain dehydrogenase 3357730 8161404 TBMG_03044 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033030.1 3356969 R 478434 CDS YP_003033031.1 253800030 8161405 complement(3357736..3358236) 1 NC_012943.1 formamidopyrimidine-DNA glycosylase 3358236 8161405 TBMG_03045 Mycobacterium tuberculosis KZN 1435 formamidopyrimidine-DNA glycosylase YP_003033031.1 3357736 R 478434 CDS YP_003033032.1 253800031 8161406 3358339..3359280 1 NC_012943.1 monooxygenase 3359280 8161406 TBMG_03046 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003033032.1 3358339 D 478434 CDS YP_003033033.1 253800032 8161407 3359659..3360432 1 NC_012943.1 hypothetical protein 3360432 8161407 TBMG_03048 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033033.1 3359659 D 478434 CDS YP_003033034.1 253800033 8161408 3360517..3361383 1 NC_012943.1 oxidoreductase 3361383 8161408 TBMG_03049 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033034.1 3360517 D 478434 CDS YP_003033035.1 253800034 8161409 complement(3361630..3363564) 1 NC_012943.1 bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase 3363564 8161409 TBMG_03050 Mycobacterium tuberculosis KZN 1435 bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase YP_003033035.1 3361630 R 478434 CDS YP_003033036.1 253800035 8161410 complement(3363561..3365840) 1 NC_012943.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; ATP-dependent DNA ligase 3365840 8161410 TBMG_03051 Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA ligase YP_003033036.1 3363561 R 478434 CDS YP_003033037.1 253800036 8161411 3365956..3366777 1 NC_012943.1 Ku protein 3366777 8161411 TBMG_03052 Mycobacterium tuberculosis KZN 1435 Ku protein YP_003033037.1 3365956 D 478434 CDS YP_003033038.1 253800037 8161412 complement(3366754..3367659) 1 NC_012943.1 phosphate ABC transporter permease 3367659 8161412 TBMG_03053 Mycobacterium tuberculosis KZN 1435 phosphate ABC transporter permease YP_003033038.1 3366754 R 478434 CDS YP_003033039.1 253800038 8161413 complement(3367661..3368677) 1 NC_012943.1 phosphate ABC transporter permease 3368677 8161413 TBMG_03054 Mycobacterium tuberculosis KZN 1435 phosphate ABC transporter permease YP_003033039.1 3367661 R 478434 CDS YP_003033040.1 253800039 8161414 complement(3368737..3369861) 1 NC_012943.1 periplasmic phosphate-binding lipoprotein pstS1 3369861 8161414 TBMG_03055 Mycobacterium tuberculosis KZN 1435 periplasmic phosphate-binding lipoprotein pstS1 YP_003033040.1 3368737 R 478434 CDS YP_003033041.1 253800040 8161415 complement(3369882..3370712) 1 NC_012943.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 3370712 8161415 TBMG_03056 Mycobacterium tuberculosis KZN 1435 phosphate ABC transporter ATP-binding protein YP_003033041.1 3369882 R 478434 CDS YP_003033042.1 253800041 8161416 3370928..3372040 1 NC_012943.1 periplasmic phosphate-binding lipoprotein pstS2 3372040 8161416 TBMG_03057 Mycobacterium tuberculosis KZN 1435 periplasmic phosphate-binding lipoprotein pstS2 YP_003033042.1 3370928 D 478434 CDS YP_003033043.1 253800042 8161417 3372062..3374056 1 NC_012943.1 Ser/Thr protein kinase 3374056 8161417 TBMG_03058 Mycobacterium tuberculosis KZN 1435 Ser/Thr protein kinase YP_003033043.1 3372062 D 478434 CDS YP_003033044.1 253800043 8161418 complement(3374063..3374977) 1 NC_012943.1 phosphate ABC transporter permease 3374977 8161418 TBMG_03059 Mycobacterium tuberculosis KZN 1435 phosphate ABC transporter permease YP_003033044.1 3374063 R 478434 CDS YP_003033045.1 253800044 8161419 complement(3374974..3375948) 1 NC_012943.1 phosphate ABC transporter permease 3375948 8161419 TBMG_03060 Mycobacterium tuberculosis KZN 1435 phosphate ABC transporter permease YP_003033045.1 3374974 R 478434 CDS YP_003033046.1 253800045 8161420 complement(3375961..3377073) 1 NC_012943.1 periplasmic phosphate-binding lipoprotein pstS3 3377073 8161420 TBMG_03061 Mycobacterium tuberculosis KZN 1435 periplasmic phosphate-binding lipoprotein pstS3 YP_003033046.1 3375961 R 478434 CDS YP_003033047.1 253800046 8161421 3377345..3378136 1 NC_012943.1 short chain dehydrogenase 3378136 8161421 TBMG_03062 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033047.1 3377345 D 478434 CDS YP_003033048.1 253800047 8161422 3378190..3379266 1 NC_012943.1 hypothetical protein 3379266 8161422 TBMG_03063 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033048.1 3378190 D 478434 CDS YP_003033049.1 253800048 8161423 3379343..3380080 1 NC_012943.1 hypothetical protein 3380080 8161423 TBMG_03064 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033049.1 3379343 D 478434 CDS YP_003033050.1 253800049 8161424 3380611..3381399 1 NC_012943.1 hypothetical protein 3381399 8161424 TBMG_03065 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033050.1 3380611 D 478434 CDS YP_003033051.1 253800050 8161425 3381400..3382464 1 NC_012943.1 hypothetical protein 3382464 8161425 TBMG_03066 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033051.1 3381400 D 478434 CDS YP_003033052.1 253800051 8161426 complement(3382640..3384292) 1 NC_012943.1 transposase 3384292 8161426 TBMG_03067 Mycobacterium tuberculosis KZN 1435 transposase YP_003033052.1 3382640 R 478434 CDS YP_003033053.1 253800052 8161427 complement(3384292..3384873) 1 NC_012943.1 resolvase 3384873 8161427 TBMG_03068 Mycobacterium tuberculosis KZN 1435 resolvase YP_003033053.1 3384292 R 478434 CDS YP_003033054.1 253800053 8161428 3385161..3386480 1 NC_012943.1 transposase 3386480 8161428 TBMG_03069 Mycobacterium tuberculosis KZN 1435 transposase YP_003033054.1 3385161 D 478434 CDS YP_003033055.1 253800054 8161430 complement(3386793..3387293) 1 NC_012943.1 hypothetical protein 3387293 8161430 TBMG_03070 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033055.1 3386793 R 478434 CDS YP_003033056.1 253800055 8161431 complement(3387290..3387766) 1 NC_012943.1 hypothetical protein 3387766 8161431 TBMG_03071 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033056.1 3387290 R 478434 CDS YP_003033057.1 253800056 8161432 complement(3387855..3388112) 1 NC_012943.1 hypothetical protein 3388112 8161432 TBMG_04092 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033057.1 3387855 R 478434 CDS YP_003033058.1 253800057 8161433 complement(3388109..3389890) 1 NC_012943.1 hypothetical protein 3389890 8161433 TBMG_03072 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033058.1 3388109 R 478434 CDS YP_003033059.1 253800058 8161434 3390334..3390633 1 NC_012943.1 PE family protein 3390633 8161434 TBMG_03073 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003033059.1 3390334 D 478434 CDS YP_003033060.1 253800059 8161435 3390648..3391919 1 NC_012943.1 PPE family protein 3391919 8161435 TBMG_03074 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033060.1 3390648 D 478434 CDS YP_003033061.1 253800060 8161436 3392012..3393250 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3393250 8161436 TBMG_03075 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003033061.1 3392012 D 478434 CDS YP_003033062.1 253800061 8161437 3393252..3394760 1 NC_012943.1 dioxygenase 3394760 8161437 TBMG_03076 Mycobacterium tuberculosis KZN 1435 dioxygenase YP_003033062.1 3393252 D 478434 CDS YP_003033063.1 253800062 8161438 3394762..3395157 1 NC_012943.1 hypothetical protein 3395157 8161438 TBMG_04093 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033063.1 3394762 D 478434 CDS YP_003033064.1 253800063 8161439 complement(3395292..3395765) 1 NC_012943.1 hypothetical protein 3395765 8161439 TBMG_03077 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033064.1 3395292 R 478434 CDS YP_003033065.1 253800064 8161440 complement(3395806..3396579) 1 NC_012943.1 hypothetical protein 3396579 8161440 TBMG_03078 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033065.1 3395806 R 478434 CDS YP_003033066.1 253800065 8161441 complement(3396677..3397111) 1 NC_012943.1 hypothetical protein 3397111 8161441 TBMG_03079 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033066.1 3396677 R 478434 CDS YP_003033067.1 253800066 8161442 complement(3397117..3397296) 1 NC_012943.1 hypothetical protein 3397296 8161442 TBMG_03080 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033067.1 3397117 R 478434 CDS YP_003033068.1 253800067 8161443 complement(3397422..3397580) 1 NC_012943.1 hypothetical protein 3397580 8161443 TBMG_04094 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033068.1 3397422 R 478434 CDS YP_003033069.1 253800068 8161444 complement(3397853..3400246) 1 NC_012943.1 metal cation transporting P-type ATPase ctpE 3400246 8161444 TBMG_03081 Mycobacterium tuberculosis KZN 1435 metal cation transporting P-type ATPase ctpE YP_003033069.1 3397853 R 478434 CDS YP_003033070.1 253800069 8161445 complement(3400243..3401931) 1 NC_012943.1 hypothetical protein 3401931 8161445 TBMG_03082 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033070.1 3400243 R 478434 CDS YP_003033071.1 253800070 8161446 complement(3401916..3403034) 1 NC_012943.1 hypothetical protein 3403034 8161446 TBMG_03083 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033071.1 3401916 R 478434 CDS YP_003033072.1 253800071 8161447 complement(3403040..3403771) 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3403771 8161447 TBMG_03084 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003033072.1 3403040 R 478434 CDS YP_003033073.1 253800072 8161448 3403798..3405285 1 NC_012943.1 acetyl-CoA carboxylase carboxyl transferase beta subunit accD3 3405285 8161448 TBMG_03085 Mycobacterium tuberculosis KZN 1435 acetyl-CoA carboxylase carboxyl transferase beta subunit accD3 YP_003033073.1 3403798 D 478434 CDS YP_003033074.1 253800073 8161449 3405416..3406126 1 NC_012943.1 two component system transcriptional regulator prrA 3406126 8161449 TBMG_03086 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator prrA YP_003033074.1 3405416 D 478434 CDS YP_003033075.1 253800074 8161450 3406137..3407477 1 NC_012943.1 two component system sensor histidine kinase prrB 3407477 8161450 TBMG_03087 Mycobacterium tuberculosis KZN 1435 two component system sensor histidine kinase prrB YP_003033075.1 3406137 D 478434 CDS YP_003033076.1 253800075 8161451 complement(3407494..3408021) 1 NC_012943.1 hypothetical protein 3408021 8161451 TBMG_03088 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033076.1 3407494 R 478434 CDS YP_003033077.1 253800076 8161452 complement(3408186..3409166) 1 NC_012943.1 hypothetical protein 3409166 8161452 TBMG_03089 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033077.1 3408186 R 478434 CDS YP_003033078.1 253800077 8161453 3409274..3409537 1 NC_012943.1 hypothetical protein 3409537 8161453 TBMG_03090 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033078.1 3409274 D 478434 CDS YP_003033079.1 253800078 8161454 3409563..3411170 1 NC_012943.1 oxidoreductase 3411170 8161454 TBMG_03091 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033079.1 3409563 D 478434 CDS YP_003033080.1 253800079 8161455 complement(3411211..3412506) 1 NC_012943.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 3412506 gltA 8161455 gltA Mycobacterium tuberculosis KZN 1435 type II citrate synthase YP_003033080.1 3411211 R 478434 CDS YP_003033081.1 253800080 8161456 complement(3412679..3414196) 1 NC_012943.1 hypothetical protein 3414196 8161456 TBMG_03093 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033081.1 3412679 R 478434 CDS YP_003033082.1 253800081 8161457 complement(3414273..3415454) 1 NC_012943.1 transcriptional regulator, luxR-family 3415454 8161457 TBMG_03094 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, luxR-family YP_003033082.1 3414273 R 478434 CDS YP_003033083.1 253800082 8161458 3415683..3416660 1 NC_012943.1 hypothetical protein 3416660 8161458 TBMG_03095 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033083.1 3415683 D 478434 CDS YP_003033084.1 253800083 8161459 complement(3416638..3416916) 1 NC_012943.1 monooxygenase 3416916 8161459 TBMG_04095 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003033084.1 3416638 R 478434 CDS YP_003033085.1 253800084 8161460 complement(3416924..3418126) 1 NC_012943.1 monooxygenase 3418126 8161460 TBMG_04096 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003033085.1 3416924 R 478434 CDS YP_003033086.1 253800085 8161461 3418524..3419381 1 NC_012943.1 transcriptional regulator 3419381 8161461 TBMG_03097 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003033086.1 3418524 D 478434 CDS YP_003033087.1 253800086 8161462 3419383..3422031 1 NC_012943.1 transcriptional regulator, luxR-family 3422031 8161462 TBMG_03098 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, luxR-family YP_003033087.1 3419383 D 478434 CDS YP_003033088.1 253800087 8161463 3422118..3423239 1 NC_012943.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; citrate synthase 2 3423239 8161463 TBMG_03099 Mycobacterium tuberculosis KZN 1435 citrate synthase 2 YP_003033088.1 3422118 D 478434 CDS YP_003033089.1 253800088 8161464 complement(3423274..3424797) 1 NC_012943.1 hypothetical protein 3424797 8161464 TBMG_03100 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033089.1 3423274 R 478434 CDS YP_003033090.1 253800089 8161465 complement(3425156..3425305) 1 NC_012943.1 hypothetical protein 3425305 8161465 TBMG_03101 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033090.1 3425156 R 478434 CDS YP_003033091.1 253800090 8161466 complement(3425444..3425710) 1 NC_012943.1 hypothetical protein 3425710 8161466 TBMG_03102 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033091.1 3425444 R 478434 CDS YP_003033092.1 253800091 8161467 3425954..3426466 1 NC_012943.1 hypothetical protein 3426466 8161467 TBMG_03103 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033092.1 3425954 D 478434 CDS YP_003033093.1 253800092 8161468 complement(3426449..3428176) 1 NC_012943.1 NADPH:adrenodoxin oxidoreductase fprB 3428176 8161468 TBMG_03104 Mycobacterium tuberculosis KZN 1435 NADPH:adrenodoxin oxidoreductase fprB YP_003033093.1 3426449 R 478434 CDS YP_003033094.1 253800093 8161469 complement(3428195..3429217) 1 NC_012943.1 hypothetical protein 3429217 8161469 TBMG_03105 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033094.1 3428195 R 478434 CDS YP_003033095.1 253800094 8161470 3429425..3430555 1 NC_012943.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 3430555 8161470 TBMG_03106 Mycobacterium tuberculosis KZN 1435 phosphoserine aminotransferase YP_003033095.1 3429425 D 478434 CDS YP_003033096.1 253800095 8161471 3430712..3431473 1 NC_012943.1 hypothetical protein 3431473 8161471 TBMG_03107 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033096.1 3430712 D 478434 CDS YP_003033097.1 253800096 8161472 complement(3431470..3431754) 1 NC_012943.1 hypothetical protein 3431754 8161472 TBMG_03108 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033097.1 3431470 R 478434 CDS YP_003033098.1 253800097 8161473 complement(3431751..3432617) 1 NC_012943.1 rRNA methyltransferase 3432617 8161473 TBMG_03109 Mycobacterium tuberculosis KZN 1435 rRNA methyltransferase YP_003033098.1 3431751 R 478434 CDS YP_003033099.1 253800098 8161474 complement(3432614..3433045) 1 NC_012943.1 transcriptional regulator, marR-family 3433045 8161474 TBMG_03110 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, marR-family YP_003033099.1 3432614 R 478434 CDS YP_003033100.1 253800099 8161475 3433223..3433498 1 NC_012943.1 hypothetical protein 3433498 8161475 TBMG_03111 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033100.1 3433223 D 478434 CDS YP_003033101.1 253800100 8161476 3433844..3435121 1 NC_012943.1 PPE family protein 3435121 8161476 TBMG_03112 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033101.1 3433844 D 478434 CDS YP_003033102.1 253800101 8161477 complement(3435116..3435904) 1 NC_012943.1 hypothetical protein 3435904 8161477 TBMG_03113 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033102.1 3435116 R 478434 CDS YP_003033103.1 253800102 8161478 3436009..3437688 1 NC_012943.1 hypothetical protein 3437688 8161478 TBMG_03114 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033103.1 3436009 D 478434 CDS YP_003033104.1 253800103 8161479 3437685..3438173 1 NC_012943.1 hypothetical protein 3438173 8161479 TBMG_03115 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033104.1 3437685 D 478434 CDS YP_003033105.1 253800104 8161480 3438273..3439433 1 NC_012943.1 hypothetical protein 3439433 8161480 TBMG_03116 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033105.1 3438273 D 478434 CDS YP_003033106.1 253800105 8161481 complement(3439522..3441474) 1 NC_012943.1 acyl-CoA dehydrogenase 3441474 8161481 TBMG_03117 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033106.1 3439522 R 478434 CDS YP_003033107.1 253800106 8161482 3441735..3443564 1 NC_012943.1 hypothetical protein 3443564 8161482 TBMG_03118 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033107.1 3441735 D 478434 CDS YP_003033108.1 253800107 8161483 complement(3443683..3444099) 1 NC_012943.1 cold shock protein B cspB 3444099 8161483 TBMG_03119 Mycobacterium tuberculosis KZN 1435 cold shock protein B cspB YP_003033108.1 3443683 R 478434 CDS YP_003033109.1 253800108 8160577 3444255..3444644 1 NC_012943.1 hypothetical protein 3444644 8160577 TBMG_03120 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033109.1 3444255 D 478434 CDS YP_003033110.1 253800109 8160741 3444641..3445723 1 NC_012943.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 3445723 moaA 8160741 moaA Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein A YP_003033110.1 3444641 D 478434 CDS YP_003033111.1 253800110 8160742 3445727..3446005 1 NC_012943.1 molybdenum cofactor biosynthesis protein D 2 moaD2 3446005 8160742 TBMG_03122 Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein D 2 moaD2 YP_003033111.1 3445727 D 478434 CDS YP_003033112.1 253800111 8160743 3446453..3447676 1 NC_012943.1 resuscitation-promoting factor rpfA 3447676 8160743 TBMG_03123 Mycobacterium tuberculosis KZN 1435 resuscitation-promoting factor rpfA YP_003033112.1 3446453 D 478434 CDS YP_003033113.1 253800112 8160744 complement(3447694..3448119) 1 NC_012943.1 molybdenum cofactor biosynthesis protein E2 moaE2 3448119 8160744 TBMG_03124 Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein E2 moaE2 YP_003033113.1 3447694 R 478434 CDS YP_003033114.1 253800113 8160745 complement(3448116..3448598) 1 NC_012943.1 molybdopterin biosynthesis protein mog 3448598 8160745 TBMG_03125 Mycobacterium tuberculosis KZN 1435 molybdopterin biosynthesis protein mog YP_003033114.1 3448116 R 478434 CDS YP_003033115.1 253800114 8160746 complement(3448595..3449098) 1 NC_012943.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 3449098 moaC 8160746 moaC Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein MoaC YP_003033115.1 3448595 R 478434 CDS YP_003033116.1 253800115 8160747 complement(3449108..3449389) 1 NC_012943.1 hypothetical protein 3449389 8160747 TBMG_03127 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033116.1 3449108 R 478434 CDS YP_003033117.1 253800116 8160749 3449376..3450776 1 NC_012943.1 truncated CDS; hypothetical protein 3450776 8160749 TBMG_03128 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033117.1 3449376 D 478434 CDS YP_003033118.1 253800117 8160748 3451889..3453517 1 NC_012943.1 DNA helicase ercc3 3453517 8160748 TBMG_03129 Mycobacterium tuberculosis KZN 1435 DNA helicase ercc3 YP_003033118.1 3451889 D 478434 CDS YP_003033119.1 253800118 8160750 complement(3453585..3455747) 1 NC_012943.1 fatty-acid oxidation protein fadB 3455747 8160750 TBMG_03130 Mycobacterium tuberculosis KZN 1435 fatty-acid oxidation protein fadB YP_003033119.1 3453585 R 478434 CDS YP_003033120.1 253800119 8160751 complement(3455752..3456963) 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3456963 8160751 TBMG_03131 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003033120.1 3455752 R 478434 CDS YP_003033121.1 253800120 8160752 3457120..3458313 1 NC_012943.1 aminotransferase 3458313 8160752 TBMG_03132 Mycobacterium tuberculosis KZN 1435 aminotransferase YP_003033121.1 3457120 D 478434 CDS YP_003033122.1 253800121 8160753 complement(3458310..3458783) 1 NC_012943.1 hypothetical protein 3458783 8160753 TBMG_03133 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033122.1 3458310 R 478434 CDS YP_003033123.1 253800122 8160754 complement(3458811..3459245) 1 NC_012943.1 hypothetical protein 3459245 8160754 TBMG_03134 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033123.1 3458811 R 478434 CDS YP_003033124.1 253800123 8160755 complement(3459329..3460408) 1 NC_012943.1 fatty-acid-CoA racemase far 3460408 8160755 TBMG_03135 Mycobacterium tuberculosis KZN 1435 fatty-acid-CoA racemase far YP_003033124.1 3459329 R 478434 CDS YP_003033125.1 253800124 8160756 complement(3460414..3460857) 1 NC_012943.1 hypothetical protein 3460857 8160756 TBMG_03136 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033125.1 3460414 R 478434 CDS YP_003033126.1 253800125 8160757 3460922..3462604 1 NC_012943.1 pyruvate or indole-3-pyruvate decarboxylase pdc 3462604 8160757 TBMG_03137 Mycobacterium tuberculosis KZN 1435 pyruvate or indole-3-pyruvate decarboxylase pdc YP_003033126.1 3460922 D 478434 CDS YP_003033127.1 253800126 8160758 complement(3462645..3463481) 1 NC_012943.1 fatty-acid-CoA ligase fadD16 3463481 8160758 TBMG_03138 Mycobacterium tuberculosis KZN 1435 fatty-acid-CoA ligase fadD16 YP_003033127.1 3462645 R 478434 CDS YP_003033128.1 253800127 8160759 3463572..3464399 1 NC_012943.1 short chain dehydrogenase 3464399 8160759 TBMG_03139 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033128.1 3463572 D 478434 CDS YP_003033129.1 253800128 8160760 complement(3464396..3464728) 1 NC_012943.1 transposase 3464728 8160760 TBMG_03140 Mycobacterium tuberculosis KZN 1435 transposase YP_003033129.1 3464396 R 478434 CDS YP_003033130.1 253800129 8160761 complement(3464725..3465984) 1 NC_012943.1 membrane transporter 3465984 8160761 TBMG_03141 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003033130.1 3464725 R 478434 CDS YP_003033131.1 253800130 8160762 complement(3465984..3467102) 1 NC_012943.1 cysteine synthase A cysK2 3467102 8160762 TBMG_03142 Mycobacterium tuberculosis KZN 1435 cysteine synthase A cysK2 YP_003033131.1 3465984 R 478434 CDS YP_003033132.1 253800131 8160763 complement(3467305..3467721) 1 NC_012943.1 hypothetical protein 3467721 8160763 TBMG_03143 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033132.1 3467305 R 478434 CDS YP_003033133.1 253800132 8160764 3467846..3469360 1 NC_012943.1 oxidase 3469360 8160764 TBMG_03144 Mycobacterium tuberculosis KZN 1435 oxidase YP_003033133.1 3467846 D 478434 CDS YP_003033134.1 253800133 8160765 complement(3469573..3470850) 1 NC_012943.1 two component system sensor kinase 3470850 8160765 TBMG_03145 Mycobacterium tuberculosis KZN 1435 two component system sensor kinase YP_003033134.1 3469573 R 478434 CDS YP_003033135.1 253800134 8160766 3470934..3471584 1 NC_012943.1 nitrate/nitrite response transcriptional regulator narL 3471584 8160766 TBMG_03146 Mycobacterium tuberculosis KZN 1435 nitrate/nitrite response transcriptional regulator narL YP_003033135.1 3470934 D 478434 CDS YP_003033136.1 253800135 8160767 complement(3471648..3472652) 1 NC_012943.1 dehydrogenase 3472652 8160767 TBMG_03147 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003033136.1 3471648 R 478434 CDS YP_003033137.1 253800136 8160768 complement(3472636..3473964) 1 NC_012943.1 hypothetical protein 3473964 8160768 TBMG_03148 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033137.1 3472636 R 478434 CDS YP_003033138.1 253800137 8160769 complement(3474205..3474447) 1 NC_012943.1 hypothetical protein 3474447 8160769 TBMG_03149 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033138.1 3474205 R 478434 CDS YP_003033139.1 253800138 8160770 3474723..3475583 1 NC_012943.1 proline iminopeptidase pip 3475583 8160770 TBMG_03150 Mycobacterium tuberculosis KZN 1435 proline iminopeptidase pip YP_003033139.1 3474723 D 478434 CDS YP_003033140.1 253800139 8160771 complement(3475651..3476463) 1 NC_012943.1 hypothetical protein 3476463 8160771 TBMG_03151 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033140.1 3475651 R 478434 CDS YP_003033141.1 253800140 8160772 complement(3476550..3477320) 1 NC_012943.1 hypothetical protein 3477320 8160772 TBMG_03152 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033141.1 3476550 R 478434 CDS YP_003033142.1 253800141 8160773 3478009..3479037 1 NC_012943.1 hypothetical protein 3479037 8160773 TBMG_03153 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033142.1 3478009 D 478434 CDS YP_003033143.1 253800142 8160774 3479015..3479761 1 NC_012943.1 hypothetical protein 3479761 8160774 TBMG_03154 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033143.1 3479015 D 478434 CDS YP_003033144.1 253800143 8160775 3479890..3480216 1 NC_012943.1 transposase 3480216 8160775 TBMG_03155 Mycobacterium tuberculosis KZN 1435 transposase YP_003033144.1 3479890 D 478434 CDS YP_003033145.1 253800144 8160776 3480267..3481151 1 NC_012943.1 transposase 3481151 8160776 TBMG_03156 Mycobacterium tuberculosis KZN 1435 transposase YP_003033145.1 3480267 D 478434 CDS YP_003033146.1 253800145 8160777 3481254..3481565 1 NC_012943.1 hydrolase 3481565 8160777 TBMG_03157 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003033146.1 3481254 D 478434 CDS YP_003033147.1 253800146 8160778 3481582..3482112 1 NC_012943.1 hypothetical protein 3482112 8160778 TBMG_03158 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033147.1 3481582 D 478434 CDS YP_003033148.1 253800147 8160779 3482211..3483521 1 NC_012943.1 transposase 3483521 8160779 TBMG_03159 Mycobacterium tuberculosis KZN 1435 transposase YP_003033148.1 3482211 D 478434 CDS YP_003033149.1 253800148 8160780 3483599..3484768 1 NC_012943.1 molybdenum cofactor biosynthesis protein moeB2 3484768 8160780 TBMG_03160 Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein moeB2 YP_003033149.1 3483599 D 478434 CDS YP_003033150.1 253800149 8160781 3484797..3485630 1 NC_012943.1 thiosulfate sulfurtransferase cysA3 3485630 8160781 TBMG_03161 Mycobacterium tuberculosis KZN 1435 thiosulfate sulfurtransferase cysA3 YP_003033150.1 3484797 D 478434 CDS YP_003033151.1 253800150 8160782 3485632..3485934 1 NC_012943.1 hypothetical protein 3485934 8160782 TBMG_03162 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033151.1 3485632 D 478434 CDS YP_003033152.1 253800151 8160783 3485955..3486398 1 NC_012943.1 molybdenum cofactor biosynthesis protein E moaE1 3486398 8160783 TBMG_03163 Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein E moaE1 YP_003033152.1 3485955 D 478434 CDS YP_003033153.1 253800152 8160784 3486395..3486997 1 NC_012943.1 hypothetical protein 3486997 8160784 TBMG_03164 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033153.1 3486395 D 478434 CDS YP_003033154.1 253800153 8160785 3487332..3488534 1 NC_012943.1 cytochrome P450 141 cyp141 3488534 8160785 TBMG_03165 Mycobacterium tuberculosis KZN 1435 cytochrome P450 141 cyp141 YP_003033154.1 3487332 D 478434 CDS YP_003033155.1 253800154 8160786 3488912..3489382 1 NC_012943.1 hypothetical protein 3489382 8160786 TBMG_03166 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033155.1 3488912 D 478434 CDS YP_003033156.1 253800155 8160787 3489392..3489886 1 NC_012943.1 hypothetical protein 3489886 8160787 TBMG_03167 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033156.1 3489392 D 478434 CDS YP_003033157.1 253800156 8160788 3490305..3491198 1 NC_012943.1 transcriptional regulator 3491198 8160788 TBMG_03168 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003033157.1 3490305 D 478434 CDS YP_003033158.1 253800157 8160789 complement(3491299..3492474) 1 NC_012943.1 PPE family protein 3492474 8160789 TBMG_03169 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033158.1 3491299 R 478434 CDS YP_003033159.1 253800158 8160790 complement(3492631..3492945) 1 NC_012943.1 hypothetical protein 3492945 8160790 TBMG_03170 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033159.1 3492631 R 478434 CDS YP_003033160.1 253800159 8160791 3492970..3494004 1 NC_012943.1 hypothetical protein 3494004 8160791 TBMG_03171 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033160.1 3492970 D 478434 CDS YP_003033161.1 253800160 8160792 complement(3493991..3494341) 1 NC_012943.1 hypothetical protein 3494341 8160792 TBMG_04097 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033161.1 3493991 R 478434 CDS YP_003033162.1 253800161 8160793 complement(3494423..3495016) 1 NC_012943.1 hypothetical protein 3495016 8160793 TBMG_03172 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033162.1 3494423 R 478434 CDS YP_003033163.1 253800162 8160794 3495483..3495815 1 NC_012943.1 hypothetical protein 3495815 8160794 TBMG_04098 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033163.1 3495483 D 478434 CDS YP_003033164.1 253800163 8160795 complement(3495798..3497189) 1 NC_012943.1 hypothetical protein 3497189 8160795 TBMG_03173 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033164.1 3495798 R 478434 CDS YP_003033165.1 253800164 8160796 3497374..3498372 1 NC_012943.1 hypothetical protein 3498372 8160796 TBMG_03174 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033165.1 3497374 D 478434 CDS YP_003033166.1 253800165 8160797 complement(3498352..3500088) 1 NC_012943.1 two component system sensor histidine kinase devS 3500088 8160797 TBMG_03175 Mycobacterium tuberculosis KZN 1435 two component system sensor histidine kinase devS YP_003033166.1 3498352 R 478434 CDS YP_003033167.1 253800166 8160798 complement(3500085..3500738) 1 NC_012943.1 two component system transcriptional regulator devR 3500738 8160798 TBMG_03176 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator devR YP_003033167.1 3500085 R 478434 CDS YP_003033168.1 253800167 8160799 complement(3500766..3501572) 1 NC_012943.1 hypothetical protein 3501572 8160799 TBMG_03177 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033168.1 3500766 R 478434 CDS YP_003033169.1 253800168 8160800 3502157..3502555 1 NC_012943.1 PPE family protein 3502555 8160800 TBMG_03178 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033169.1 3502157 D 478434 CDS YP_003033170.1 253800169 8160801 3502617..3503759 1 NC_012943.1 PPE family protein 3503759 8160801 TBMG_03179 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033170.1 3502617 D 478434 CDS YP_003033171.1 253800170 8160802 complement(3503768..3504100) 1 NC_012943.1 hypothetical protein 3504100 8160802 TBMG_04099 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033171.1 3503768 R 478434 CDS YP_003033172.1 253800171 8160803 3504216..3504998 1 NC_012943.1 monophosphatase 3504998 8160803 TBMG_03180 Mycobacterium tuberculosis KZN 1435 monophosphatase YP_003033172.1 3504216 D 478434 CDS YP_003033173.1 253800172 8160804 3505018..3506106 1 NC_012943.1 pyruvate formate lyase activating protein pflA 3506106 8160804 TBMG_03181 Mycobacterium tuberculosis KZN 1435 pyruvate formate lyase activating protein pflA YP_003033173.1 3505018 D 478434 CDS YP_003033174.1 253800173 8160805 3506186..3507592 1 NC_012943.1 acyl-CoA dehydrogenase 3507592 8160805 TBMG_03182 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033174.1 3506186 D 478434 CDS YP_003033175.1 253800174 8160806 3507613..3508818 1 NC_012943.1 acyl-CoA dehydrogenase 3508818 8160806 TBMG_03183 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033175.1 3507613 D 478434 CDS YP_003033176.1 253800175 8160807 3508918..3509889 1 NC_012943.1 NADPH quinone oxidoreductase fadB4 3509889 8160807 TBMG_03184 Mycobacterium tuberculosis KZN 1435 NADPH quinone oxidoreductase fadB4 YP_003033176.1 3508918 D 478434 CDS YP_003033177.1 253800176 8160808 complement(3509941..3510369) 1 NC_012943.1 hypothetical protein 3510369 8160808 TBMG_03185 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033177.1 3509941 R 478434 CDS YP_003033178.1 253800177 8160809 3510477..3510878 1 NC_012943.1 response regulator 3510878 8160809 TBMG_03186 Mycobacterium tuberculosis KZN 1435 response regulator YP_003033178.1 3510477 D 478434 CDS YP_003033179.1 253800178 8160810 complement(3510911..3512128) 1 NC_012943.1 PPE family protein 3512128 8160810 TBMG_03187 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033179.1 3510911 R 478434 CDS YP_003033180.1 253800179 8160811 3512400..3512891 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 3512891 8160811 TBMG_03188 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit A YP_003033180.1 3512400 D 478434 CDS YP_003033181.1 253800180 8160812 3512900..3513454 1 NC_012943.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 3513454 8160812 TBMG_03189 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit B YP_003033181.1 3512900 D 478434 CDS YP_003033182.1 253800181 8160813 3513451..3514161 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 3514161 8160813 TBMG_03190 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit C YP_003033182.1 3513451 D 478434 CDS YP_003033183.1 253800182 8160814 3514161..3515483 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 3515483 8160814 TBMG_03191 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit D YP_003033183.1 3514161 D 478434 CDS YP_003033184.1 253800183 8160815 3515480..3516238 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 3516238 8160815 TBMG_03192 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit E YP_003033184.1 3515480 D 478434 CDS YP_003033185.1 253800184 8160816 3516235..3517572 1 NC_012943.1 NADH dehydrogenase subunit I F nuoF 3517572 8160816 TBMG_03193 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit I F nuoF YP_003033185.1 3516235 D 478434 CDS YP_003033186.1 253800185 8160817 3517569..3519989 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 3519989 8160817 TBMG_03194 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit G YP_003033186.1 3517569 D 478434 CDS YP_003033187.1 253800186 8160818 3520105..3521337 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 3521337 8160818 TBMG_03195 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit H YP_003033187.1 3520105 D 478434 CDS YP_003033188.1 253800187 8160819 3521309..3521965 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 3521965 8160819 TBMG_03196 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit I YP_003033188.1 3521309 D 478434 CDS YP_003033189.1 253800188 8160820 3521962..3522750 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 3522750 8160820 TBMG_03197 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit J YP_003033189.1 3521962 D 478434 CDS YP_003033190.1 253800189 8160821 3522747..3523046 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 3523046 8160821 TBMG_03198 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit K YP_003033190.1 3522747 D 478434 CDS YP_003033191.1 253800190 8162494 3523057..3524958 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 3524958 8162494 TBMG_03199 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit L YP_003033191.1 3523057 D 478434 CDS YP_003033192.1 253800191 8162583 3524955..3526616 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 3526616 8162583 TBMG_03200 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit M YP_003033192.1 3524955 D 478434 CDS YP_003033193.1 253800192 8162584 3526613..3528208 1 NC_012943.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 3528208 8162584 TBMG_03201 Mycobacterium tuberculosis KZN 1435 NADH dehydrogenase subunit N YP_003033193.1 3526613 D 478434 CDS YP_003033194.1 253800193 8162585 complement(3528214..3530145) 1 NC_012943.1 PPE family protein 3530145 8162585 TBMG_03202 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033194.1 3528214 R 478434 CDS YP_003033195.1 253800194 8162586 complement(3530161..3530802) 1 NC_012943.1 TetR family transcriptional regulator 3530802 8162586 TBMG_03203 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033195.1 3530161 R 478434 CDS YP_003033196.1 253800195 8162587 complement(3530813..3531970) 1 NC_012943.1 dioxygenase 3531970 8162587 TBMG_03204 Mycobacterium tuberculosis KZN 1435 dioxygenase YP_003033196.1 3530813 R 478434 CDS YP_003033197.1 253800196 8162588 complement(3532031..3532468) 1 NC_012943.1 hypothetical protein 3532468 8162588 TBMG_03205 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033197.1 3532031 R 478434 CDS YP_003033198.1 253800197 8162589 complement(3532465..3533736) 1 NC_012943.1 hypothetical protein 3533736 8162589 TBMG_03206 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033198.1 3532465 R 478434 CDS YP_003033199.1 253800198 8162590 complement(3533766..3534728) 1 NC_012943.1 methanol dehydrogenase transcriptional regulator moxR3 3534728 8162590 TBMG_03207 Mycobacterium tuberculosis KZN 1435 methanol dehydrogenase transcriptional regulator moxR3 YP_003033199.1 3533766 R 478434 CDS YP_003033200.1 253800199 8162591 complement(3534736..3535218) 1 NC_012943.1 hypothetical protein 3535218 8162591 TBMG_03208 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033200.1 3534736 R 478434 CDS YP_003033201.1 253800200 8162592 complement(3535215..3536174) 1 NC_012943.1 hypothetical protein 3536174 8162592 TBMG_03209 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033201.1 3535215 R 478434 CDS YP_003033202.1 253800201 8162593 complement(3536254..3536880) 1 NC_012943.1 TetR family transcriptional regulator 3536880 8162593 TBMG_03210 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033202.1 3536254 R 478434 CDS YP_003033203.1 253800202 8162594 3536925..3538061 1 NC_012943.1 hypothetical protein 3538061 8162594 TBMG_03211 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033203.1 3536925 D 478434 CDS YP_003033204.1 253800203 8162595 3538061..3539185 1 NC_012943.1 hypothetical protein 3539185 8162595 TBMG_03212 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033204.1 3538061 D 478434 CDS YP_003033205.1 253800204 8162596 3539310..3540674 1 NC_012943.1 flavin-containing monoamine oxidase aofH 3540674 8162596 TBMG_03213 Mycobacterium tuberculosis KZN 1435 flavin-containing monoamine oxidase aofH YP_003033205.1 3539310 D 478434 CDS YP_003033206.1 253800205 8162597 complement(3540669..3541568) 1 NC_012943.1 non-heme haloperoxidase hpx 3541568 8162597 TBMG_03214 Mycobacterium tuberculosis KZN 1435 non-heme haloperoxidase hpx YP_003033206.1 3540669 R 478434 CDS YP_003033207.1 253800206 8162598 complement(3541705..3542187) 1 NC_012943.1 hypothetical protein 3542187 8162598 TBMG_03215 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033207.1 3541705 R 478434 CDS YP_003033208.1 253800207 8162599 complement(3542266..3542868) 1 NC_012943.1 TetR family transcriptional regulator 3542868 8162599 TBMG_03216 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033208.1 3542266 R 478434 CDS YP_003033209.1 253800208 8162600 3542961..3543668 1 NC_012943.1 short chain dehydrogenase 3543668 8162600 TBMG_03217 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033209.1 3542961 D 478434 CDS YP_003033210.1 253800209 8162601 3543683..3545170 1 NC_012943.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 3545170 8162601 TBMG_03218 Mycobacterium tuberculosis KZN 1435 amidase YP_003033210.1 3543683 D 478434 CDS YP_003033211.1 253800210 8162602 complement(3545167..3546123) 1 NC_012943.1 epoxide hydrolase mesT 3546123 8162602 TBMG_03219 Mycobacterium tuberculosis KZN 1435 epoxide hydrolase mesT YP_003033211.1 3545167 R 478434 CDS YP_003033212.1 253800211 8162603 3546270..3547130 1 NC_012943.1 peroxidase 3547130 8162603 TBMG_03220 Mycobacterium tuberculosis KZN 1435 peroxidase YP_003033212.1 3546270 D 478434 CDS YP_003033213.1 253800212 8162604 3547261..3547620 1 NC_012943.1 hypothetical protein 3547620 8162604 TBMG_03221 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033213.1 3547261 D 478434 CDS YP_003033214.1 253800213 8162605 3547860..3548153 1 NC_012943.1 hypothetical protein 3548153 8162605 TBMG_03222 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033214.1 3547860 D 478434 CDS YP_003033215.1 253800214 8162606 3548366..3549730 1 NC_012943.1 hypothetical protein 3549730 8162606 TBMG_03223 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033215.1 3548366 D 478434 CDS YP_003033216.1 253800215 8162607 complement(3550077..3550511) 1 NC_012943.1 hypothetical protein 3550511 8162607 TBMG_03224 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033216.1 3550077 R 478434 CDS YP_003033217.1 253800216 8162608 complement(3550514..3550966) 1 NC_012943.1 hypothetical protein 3550966 8162608 TBMG_03225 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033217.1 3550514 R 478434 CDS YP_003033218.1 253800217 8162609 3551197..3551541 1 NC_012943.1 hypothetical protein 3551541 8162609 TBMG_03226 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033218.1 3551197 D 478434 CDS YP_003033219.1 253800218 8162610 3551538..3551867 1 NC_012943.1 transcriptional regulator 3551867 8162610 TBMG_03227 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003033219.1 3551538 D 478434 CDS YP_003033220.1 253800219 8162611 3552405..3552752 1 NC_012943.1 hypothetical protein 3552752 8162611 TBMG_03228 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033220.1 3552405 D 478434 CDS YP_003033221.1 253800220 8162612 3552749..3553369 1 NC_012943.1 hypothetical protein 3553369 8162612 TBMG_03229 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033221.1 3552749 D 478434 CDS YP_003033222.1 253800221 8162613 complement(3553529..3554794) 1 NC_012943.1 hypothetical protein 3554794 8162613 TBMG_03230 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033222.1 3553529 R 478434 CDS YP_003033223.1 253800222 8162614 complement(3555418..3556602) 1 NC_012943.1 transposase 3556602 8162614 TBMG_03231 Mycobacterium tuberculosis KZN 1435 transposase YP_003033223.1 3555418 R 478434 CDS YP_003033224.1 253800223 8162615 complement(3556736..3556960) 1 NC_012943.1 hypothetical protein 3556960 8162615 TBMG_04100 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033224.1 3556736 R 478434 CDS YP_003033225.1 253800224 8162616 complement(3556905..3557087) 1 NC_012943.1 hypothetical protein 3557087 8162616 TBMG_04101 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033225.1 3556905 R 478434 CDS YP_003033226.1 253800225 8162618 3557667..3558131 1 NC_012943.1 hypothetical protein 3558131 8162618 TBMG_03232 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033226.1 3557667 D 478434 CDS YP_003033227.1 253800226 8162619 complement(3558301..3561279) 1 NC_012943.1 hypothetical protein 3561279 8162619 TBMG_03233 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033227.1 3558301 R 478434 CDS YP_003033228.1 253800227 8162620 complement(3561371..3562393) 1 NC_012943.1 hypothetical protein 3562393 8162620 TBMG_03234 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033228.1 3561371 R 478434 CDS YP_003033229.1 253800228 8162621 3562471..3563889 1 NC_012943.1 hypothetical protein 3563889 8162621 TBMG_03235 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033229.1 3562471 D 478434 CDS YP_003033230.1 253800229 8162622 3563895..3564794 1 NC_012943.1 hypothetical protein 3564794 8162622 TBMG_03236 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033230.1 3563895 D 478434 CDS YP_003033231.1 253800230 8162623 complement(3564803..3565003) 1 NC_012943.1 hypothetical protein 3565003 8162623 TBMG_03237 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033231.1 3564803 R 478434 CDS YP_003033232.1 253800231 8162624 3565131..3566474 1 NC_012943.1 ABC transporter ATP-binding protein 3566474 8162624 TBMG_03238 Mycobacterium tuberculosis KZN 1435 ABC transporter ATP-binding protein YP_003033232.1 3565131 D 478434 CDS YP_003033233.1 253800232 8162625 complement(3566508..3566786) 1 NC_012943.1 transcriptional regulator whib-like whiB7 3566786 8162625 TBMG_03239 Mycobacterium tuberculosis KZN 1435 transcriptional regulator whib-like whiB7 YP_003033233.1 3566508 R 478434 CDS YP_003033234.1 253800233 8162626 complement(3567216..3569405) 1 NC_012943.1 ATP-dependent DNA helicase II uvrD2 3569405 8162626 TBMG_03240 Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA helicase II uvrD2 YP_003033234.1 3567216 R 478434 CDS YP_003033235.1 253800234 8162627 3569442..3569696 1 NC_012943.1 glutaredoxin 3569696 8162627 TBMG_03241 Mycobacterium tuberculosis KZN 1435 glutaredoxin YP_003033235.1 3569442 D 478434 CDS YP_003033236.1 253800235 8162628 complement(3569709..3570650) 1 NC_012943.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 3570650 nudC 8162628 nudC Mycobacterium tuberculosis KZN 1435 NADH pyrophosphatase YP_003033236.1 3569709 R 478434 CDS YP_003033237.1 253800236 8162629 complement(3570709..3571776) 1 NC_012943.1 transmembrane cation transporter 3571776 8162629 TBMG_03243 Mycobacterium tuberculosis KZN 1435 transmembrane cation transporter YP_003033237.1 3570709 R 478434 CDS YP_003033238.1 253800237 8162630 complement(3571838..3575143) 1 NC_012943.1 ATP-dependent DNA helicase 3575143 8162630 TBMG_03244 Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA helicase YP_003033238.1 3571838 R 478434 CDS YP_003033239.1 253800238 8162631 complement(3575140..3578307) 1 NC_012943.1 ATP-dependent DNA helicase 3578307 8162631 TBMG_03245 Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA helicase YP_003033239.1 3575140 R 478434 CDS YP_003033240.1 253800239 8162632 3578393..3578602 1 NC_012943.1 hypothetical protein 3578602 8162632 TBMG_03246 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033240.1 3578393 D 478434 CDS YP_003033241.1 253800240 8162633 3578633..3579418 1 NC_012943.1 lipase lipV 3579418 8162633 TBMG_03247 Mycobacterium tuberculosis KZN 1435 lipase lipV YP_003033241.1 3578633 D 478434 CDS YP_003033242.1 253800241 8162634 3579421..3579726 1 NC_012943.1 DNA-methyltransferase 3579726 8162634 TBMG_03248 Mycobacterium tuberculosis KZN 1435 DNA-methyltransferase YP_003033242.1 3579421 D 478434 CDS YP_003033243.1 253800242 8162635 complement(3579733..3580611) 1 NC_012943.1 hypothetical protein 3580611 8162635 TBMG_03249 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033243.1 3579733 R 478434 CDS YP_003033244.1 253800243 8162636 complement(3580638..3581816) 1 NC_012943.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; molybdopterin biosynthesis-like protein MoeZ 3581816 8162636 TBMG_03250 Mycobacterium tuberculosis KZN 1435 molybdopterin biosynthesis-like protein MoeZ YP_003033244.1 3580638 R 478434 CDS YP_003033245.1 253800244 8162637 complement(3581907..3582893) 1 NC_012943.1 hypothetical protein 3582893 8162637 TBMG_03251 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033245.1 3581907 R 478434 CDS YP_003033246.1 253800245 8162638 3583110..3583796 1 NC_012943.1 TetR family transcriptional regulator 3583796 8162638 TBMG_03252 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033246.1 3583110 D 478434 CDS YP_003033247.1 253800246 8162639 complement(3583783..3584070) 1 NC_012943.1 hypothetical protein 3584070 8162639 TBMG_03253 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033247.1 3583783 R 478434 CDS YP_003033248.1 253800247 8162640 complement(3584262..3584591) 1 NC_012943.1 helicase 3584591 8162640 TBMG_04102 Mycobacterium tuberculosis KZN 1435 helicase YP_003033248.1 3584262 R 478434 CDS YP_003033249.1 253800248 8162642 3584380..3584940 1 NC_012943.1 hypothetical protein 3584940 8162642 TBMG_03254 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033249.1 3584380 D 478434 CDS YP_003033250.1 253800249 8162641 complement(3584950..3585645) 1 NC_012943.1 hypothetical protein 3585645 8162641 TBMG_03255 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033250.1 3584950 R 478434 CDS YP_003033251.1 253800250 8162643 3585904..3587487 1 NC_012943.1 ATP-dependent RNA helicase rhlE 3587487 8162643 TBMG_03256 Mycobacterium tuberculosis KZN 1435 ATP-dependent RNA helicase rhlE YP_003033251.1 3585904 D 478434 CDS YP_003033252.1 253800251 8162644 3587500..3588723 1 NC_012943.1 hypothetical protein 3588723 8162644 TBMG_03257 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033252.1 3587500 D 478434 CDS YP_003033253.1 253800252 8162645 complement(3588799..3589599) 1 NC_012943.1 chromosome partitioning protein 3589599 8162645 TBMG_03258 Mycobacterium tuberculosis KZN 1435 chromosome partitioning protein YP_003033253.1 3588799 R 478434 CDS YP_003033254.1 253800253 8162646 3589678..3590364 1 NC_012943.1 forms a homodimer in Mycobacterium tuberculosis; belongs to the dPGM superfamily; acid phosphatase 3590364 8162646 TBMG_03259 Mycobacterium tuberculosis KZN 1435 acid phosphatase YP_003033254.1 3589678 D 478434 CDS YP_003033255.1 253800254 8162647 3590361..3591479 1 NC_012943.1 isochorismate synthase entC 3591479 8162647 TBMG_03260 Mycobacterium tuberculosis KZN 1435 isochorismate synthase entC YP_003033255.1 3590361 D 478434 CDS YP_003033256.1 253800255 8162648 3591627..3591959 1 NC_012943.1 acetyltransferase 3591959 8162648 TBMG_03261 Mycobacterium tuberculosis KZN 1435 acetyltransferase YP_003033256.1 3591627 D 478434 CDS YP_003033257.1 253800256 8162649 complement(3591911..3592342) 1 NC_012943.1 hypothetical protein 3592342 8162649 TBMG_03262 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033257.1 3591911 R 478434 CDS YP_003033258.1 253800257 8162650 3592575..3593540 1 NC_012943.1 hypothetical protein 3593540 8162650 TBMG_03263 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033258.1 3592575 D 478434 CDS YP_003033259.1 253800258 8162651 3593833..3594087 1 NC_012943.1 transcriptional regulator whib-like whiB1 3594087 8162651 TBMG_03264 Mycobacterium tuberculosis KZN 1435 transcriptional regulator whib-like whiB1 YP_003033259.1 3593833 D 478434 CDS YP_003033260.1 253800259 8162652 complement(3594149..3595654) 1 NC_012943.1 two component system sensor kinase 3595654 8162652 TBMG_03265 Mycobacterium tuberculosis KZN 1435 two component system sensor kinase YP_003033260.1 3594149 R 478434 CDS YP_003033261.1 253800260 8162653 complement(3595671..3595910) 1 NC_012943.1 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3595910 8162653 TBMG_03266 Mycobacterium tuberculosis KZN 1435 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_003033261.1 3595671 R 478434 CDS YP_003033262.1 253800261 8162654 complement(3596171..3596476) 1 NC_012943.1 anti-sigma factor 3596476 8162654 TBMG_03267 Mycobacterium tuberculosis KZN 1435 anti-sigma factor YP_003033262.1 3596171 R 478434 CDS YP_003033263.1 253800262 8162655 complement(3596473..3597024) 1 NC_012943.1 hypothetical protein 3597024 8162655 TBMG_03268 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033263.1 3596473 R 478434 CDS YP_003033264.1 253800263 8162656 complement(3597021..3597788) 1 NC_012943.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 3597788 8162656 TBMG_03269 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor RpoE YP_003033264.1 3597021 R 478434 CDS YP_003033265.1 253800264 8162657 3597971..3598819 1 NC_012943.1 short chain dehydrogenase 3598819 8162657 TBMG_03270 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033265.1 3597971 D 478434 CDS YP_003033266.1 253800265 8162658 3598755..3598943 1 NC_012943.1 hypothetical protein 3598943 8162658 TBMG_03271 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033266.1 3598755 D 478434 CDS YP_003033267.1 253800266 8162659 3598921..3599139 1 NC_012943.1 hypothetical protein 3599139 8162659 TBMG_03272 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033267.1 3598921 D 478434 CDS YP_003033268.1 253800267 8162660 complement(3599136..3600560) 1 NC_012943.1 transferase 3600560 8162660 TBMG_03273 Mycobacterium tuberculosis KZN 1435 transferase YP_003033268.1 3599136 R 478434 CDS YP_003033269.1 253800268 8162661 complement(3600684..3601442) 1 NC_012943.1 hypothetical protein 3601442 8162661 TBMG_03274 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033269.1 3600684 R 478434 CDS YP_003033270.1 253800269 8162662 3601497..3602849 1 NC_012943.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 3602849 8162662 TBMG_03275 Mycobacterium tuberculosis KZN 1435 3-phosphoshikimate 1-carboxyvinyltransferase YP_003033270.1 3601497 D 478434 CDS YP_003033271.1 253800270 8162663 3602846..3603838 1 NC_012943.1 hypothetical protein 3603838 8162663 TBMG_03276 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033271.1 3602846 D 478434 CDS YP_003033272.1 253800271 8163622 complement(3603871..3605154) 1 NC_012943.1 linoleoyl-CoA desaturase 3605154 8163622 TBMG_03277 Mycobacterium tuberculosis KZN 1435 linoleoyl-CoA desaturase YP_003033272.1 3603871 R 478434 CDS YP_003033273.1 253800272 8162087 complement(3605232..3606374) 1 NC_012943.1 oxidoreductase 3606374 8162087 TBMG_03278 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033273.1 3605232 R 478434 CDS YP_003033274.1 253800273 8162088 complement(3606484..3606993) 1 NC_012943.1 hypothetical protein 3606993 8162088 TBMG_03279 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033274.1 3606484 R 478434 CDS YP_003033275.1 253800274 8162089 complement(3606990..3607877) 1 NC_012943.1 transcriptional regulator pvdS 3607877 8162089 TBMG_03280 Mycobacterium tuberculosis KZN 1435 transcriptional regulator pvdS YP_003033275.1 3606990 R 478434 CDS YP_003033276.1 253800275 8162090 complement(3607901..3608503) 1 NC_012943.1 hypothetical protein 3608503 8162090 TBMG_03281 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033276.1 3607901 R 478434 CDS YP_003033277.1 253800276 8162091 complement(3608494..3609309) 1 NC_012943.1 hypothetical protein 3609309 8162091 TBMG_03282 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033277.1 3608494 R 478434 CDS YP_003033278.1 253800277 8162092 3609420..3610061 1 NC_012943.1 hypothetical protein 3610061 8162092 TBMG_03283 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033278.1 3609420 D 478434 CDS YP_003033279.1 253800278 8162093 complement(3610079..3611236) 1 NC_012943.1 membrane transporter 3611236 8162093 TBMG_03284 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003033279.1 3610079 R 478434 CDS YP_003033280.1 253800279 8162094 complement(3611241..3611723) 1 NC_012943.1 hypothetical protein 3611723 8162094 TBMG_03285 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033280.1 3611241 R 478434 CDS YP_003033281.1 253800280 8162095 complement(3611784..3612518) 1 NC_012943.1 hypothetical protein 3612518 8162095 TBMG_03286 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033281.1 3611784 R 478434 CDS YP_003033282.1 253800281 8162096 complement(3612577..3615723) 1 NC_012943.1 membrane transporter 3615723 8162096 TBMG_03287 Mycobacterium tuberculosis KZN 1435 membrane transporter YP_003033282.1 3612577 R 478434 CDS YP_003033283.1 253800282 8162097 complement(3615802..3618651) 1 NC_012943.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 3618651 8162097 TBMG_03288 Mycobacterium tuberculosis KZN 1435 preprotein translocase subunit SecA YP_003033283.1 3615802 R 478434 CDS YP_003033284.1 253800283 8162098 complement(3618730..3619374) 1 NC_012943.1 hypothetical protein 3619374 8162098 TBMG_03289 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033284.1 3618730 R 478434 CDS YP_003033285.1 253800284 8162099 complement(3619690..3620331) 1 NC_012943.1 hypothetical protein 3620331 8162099 TBMG_03290 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033285.1 3619690 R 478434 CDS YP_003033286.1 253800285 8162100 complement(3620369..3621211) 1 NC_012943.1 hypothetical protein 3621211 8162100 TBMG_03291 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033286.1 3620369 R 478434 CDS YP_003033287.1 253800286 8162101 complement(3621279..3623042) 1 NC_012943.1 lipoprotein LpqB 3623042 8162101 TBMG_03292 Mycobacterium tuberculosis KZN 1435 lipoprotein LpqB YP_003033287.1 3621279 R 478434 CDS YP_003033288.1 253800287 8162102 complement(3623030..3624733) 1 NC_012943.1 two component system sensor histidine kinase mtrB 3624733 8162102 TBMG_03293 Mycobacterium tuberculosis KZN 1435 two component system sensor histidine kinase mtrB YP_003033288.1 3623030 R 478434 CDS YP_003033289.1 253800288 8162103 complement(3624783..3625469) 1 NC_012943.1 two component system transcriptional regulator mtrA 3625469 8162103 TBMG_03294 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator mtrA YP_003033289.1 3624783 R 478434 CDS YP_003033290.1 253800289 8162104 complement(3625539..3626183) 1 NC_012943.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 3626183 8162104 TBMG_03295 Mycobacterium tuberculosis KZN 1435 thymidylate kinase YP_003033290.1 3625539 R 478434 CDS YP_003033291.1 253800290 8162105 complement(3626280..3627767) 1 NC_012943.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 3627767 8162105 TBMG_03296 Mycobacterium tuberculosis KZN 1435 S-adenosyl-L-homocysteine hydrolase YP_003033291.1 3626280 R 478434 CDS YP_003033292.1 253800291 8162106 complement(3627872..3628507) 1 NC_012943.1 TetR family transcriptional regulator 3628507 8162106 TBMG_03297 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033292.1 3627872 R 478434 CDS YP_003033293.1 253800292 8162107 complement(3628504..3628686) 1 NC_012943.1 rubredoxin rubB 3628686 8162107 TBMG_03298 Mycobacterium tuberculosis KZN 1435 rubredoxin rubB YP_003033293.1 3628504 R 478434 CDS YP_003033294.1 253800293 8162108 complement(3628691..3628858) 1 NC_012943.1 rubredoxin rubA 3628858 8162108 TBMG_03299 Mycobacterium tuberculosis KZN 1435 rubredoxin rubA YP_003033294.1 3628691 R 478434 CDS YP_003033295.1 253800294 8162109 complement(3628858..3630108) 1 NC_012943.1 transmembrane alkane 1-monooxygenase alkB 3630108 8162109 TBMG_03300 Mycobacterium tuberculosis KZN 1435 transmembrane alkane 1-monooxygenase alkB YP_003033295.1 3628858 R 478434 CDS YP_003033296.1 253800295 8162110 complement(3630217..3631704) 1 NC_012943.1 hypothetical protein 3631704 8162110 TBMG_03301 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033296.1 3630217 R 478434 CDS YP_003033297.1 253800296 8162111 3631759..3633183 1 NC_012943.1 hypothetical protein 3633183 8162111 TBMG_03302 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033297.1 3631759 D 478434 CDS YP_003033298.1 253800297 8162112 complement(3633161..3634387) 1 NC_012943.1 mannose-6-phosphate isomerase 3634387 8162112 TBMG_03303 Mycobacterium tuberculosis KZN 1435 mannose-6-phosphate isomerase YP_003033298.1 3633161 R 478434 CDS YP_003033299.1 253800298 8162113 complement(3634395..3635435) 1 NC_012943.1 hypothetical protein 3635435 8162113 TBMG_03304 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033299.1 3634395 R 478434 CDS YP_003033300.1 253800299 8162114 complement(3635432..3636829) 1 NC_012943.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase/phosphoglucomutase 3636829 manB 8162114 manB Mycobacterium tuberculosis KZN 1435 phosphomannomutase/phosphoglucomutase YP_003033300.1 3635432 R 478434 CDS YP_003033301.1 253800300 8162115 complement(3636931..3637422) 1 NC_012943.1 hypothetical protein 3637422 8162115 TBMG_03306 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033301.1 3636931 R 478434 CDS YP_003033302.1 253800301 8162116 3637437..3637964 1 NC_012943.1 hypothetical protein 3637964 8162116 TBMG_03307 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033302.1 3637437 D 478434 CDS YP_003033303.1 253800302 8162117 complement(3637992..3638363) 1 NC_012943.1 transcriptional regulator whib-like whiB2 3638363 8162117 TBMG_03308 Mycobacterium tuberculosis KZN 1435 transcriptional regulator whib-like whiB2 YP_003033303.1 3637992 R 478434 CDS YP_003033304.1 253800303 8162118 3638663..3639658 1 NC_012943.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); LPPG:FO 2-phospho-L-lactate transferase 3639658 8162118 TBMG_03309 Mycobacterium tuberculosis KZN 1435 LPPG:FO 2-phospho-L-lactate transferase YP_003033304.1 3638663 D 478434 CDS YP_003033305.1 253800304 8162119 3639655..3641001 1 NC_012943.1 catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); F420-0--gamma-glutamyl ligase 3641001 8162119 TBMG_03310 Mycobacterium tuberculosis KZN 1435 F420-0--gamma-glutamyl ligase YP_003033305.1 3639655 D 478434 CDS YP_003033306.1 253800305 8162120 3641034..3641147 1 NC_012943.1 hypothetical protein 3641147 8162120 TBMG_04103 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033306.1 3641034 D 478434 CDS YP_003033307.1 253800306 8162121 3641297..3642958 1 NC_012943.1 DNA methylase 3642958 8162121 TBMG_03311 Mycobacterium tuberculosis KZN 1435 DNA methylase YP_003033307.1 3641297 D 478434 CDS YP_003033308.1 253800307 8162122 complement(3643018..3644097) 1 NC_012943.1 D-alpha-D-mannose-1-phosphate guanylyltransferase manB 3644097 8162122 TBMG_03312 Mycobacterium tuberculosis KZN 1435 D-alpha-D-mannose-1-phosphate guanylyltransferase manB YP_003033308.1 3643018 R 478434 CDS YP_003033309.1 253800308 8162123 complement(3644099..3645022) 1 NC_012943.1 dTDP-rha:a-D-glcnac-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase wbbL1 3645022 8162123 TBMG_03313 Mycobacterium tuberculosis KZN 1435 dTDP-rha:a-D-glcnac-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase wbbL1 YP_003033309.1 3644099 R 478434 CDS YP_003033310.1 253800309 8162124 complement(3645015..3645929) 1 NC_012943.1 dTDP-6-deoxy-L-lyxo-4-hexulose reductase rmlD 3645929 8162124 TBMG_03314 Mycobacterium tuberculosis KZN 1435 dTDP-6-deoxy-L-lyxo-4-hexulose reductase rmlD YP_003033310.1 3645015 R 478434 CDS YP_003033311.1 253800310 8162125 3646005..3647501 1 NC_012943.1 hypothetical protein 3647501 8162125 TBMG_03315 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033311.1 3646005 D 478434 CDS YP_003033312.1 253800311 8162126 3647489..3648229 1 NC_012943.1 hypothetical protein 3648229 8162126 TBMG_03316 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033312.1 3647489 D 478434 CDS YP_003033313.1 253800312 8162127 3648354..3648635 1 NC_012943.1 hypothetical protein 3648635 8162127 TBMG_03317 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033313.1 3648354 D 478434 CDS YP_003033314.1 253800313 8162128 3648646..3650802 1 NC_012943.1 metal cation transporting P-type ATPase ctpC 3650802 8162128 TBMG_03318 Mycobacterium tuberculosis KZN 1435 metal cation transporting P-type ATPase ctpC YP_003033314.1 3648646 D 478434 CDS YP_003033315.1 253800314 8162129 complement(3650799..3651467) 1 NC_012943.1 hypothetical protein 3651467 8162129 TBMG_03319 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033315.1 3650799 R 478434 CDS YP_003033316.1 253800315 8162130 3651568..3652752 1 NC_012943.1 hypothetical protein 3652752 8162130 TBMG_03320 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033316.1 3651568 D 478434 CDS YP_003033317.1 253800316 8162131 3652757..3655051 1 NC_012943.1 transmembrane carbonic anhydrase 3655051 8162131 TBMG_03321 Mycobacterium tuberculosis KZN 1435 transmembrane carbonic anhydrase YP_003033317.1 3652757 D 478434 CDS YP_003033318.1 253800317 8162132 complement(3655040..3656209) 1 NC_012943.1 acyl-CoA dehydrogenase 3656209 8162132 TBMG_03322 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033318.1 3655040 R 478434 CDS YP_003033319.1 253800318 8162133 complement(3656234..3656758) 1 NC_012943.1 phosphoribosylaminoimidazole carboxylase catalytic subunit purE 3656758 8162133 TBMG_03323 Mycobacterium tuberculosis KZN 1435 phosphoribosylaminoimidazole carboxylase catalytic subunit purE YP_003033319.1 3656234 R 478434 CDS YP_003033320.1 253800319 8162134 complement(3656755..3658044) 1 NC_012943.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 3658044 8162134 TBMG_03324 Mycobacterium tuberculosis KZN 1435 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_003033320.1 3656755 R 478434 CDS YP_003033321.1 253800320 8162136 3657998..3658816 1 NC_012943.1 hypothetical protein 3658816 8162136 TBMG_03325 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033321.1 3657998 D 478434 CDS YP_003033322.1 253800321 8162135 complement(3658771..3659289) 1 NC_012943.1 hypothetical protein 3659289 8162135 TBMG_03326 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033322.1 3658771 R 478434 CDS YP_003033323.1 253800322 8162137 complement(3659332..3660132) 1 NC_012943.1 biotin-protein ligase 3660132 8162137 TBMG_03327 Mycobacterium tuberculosis KZN 1435 biotin-protein ligase YP_003033323.1 3659332 R 478434 CDS YP_003033324.1 253800323 8162138 3660182..3661828 1 NC_012943.1 propionyl-CoA carboxylase subunit beta 3661828 8162138 TBMG_03328 Mycobacterium tuberculosis KZN 1435 propionyl-CoA carboxylase subunit beta YP_003033324.1 3660182 D 478434 CDS YP_003033325.1 253800324 8162139 3661809..3662279 1 NC_012943.1 hypothetical protein 3662279 8162139 TBMG_03329 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033325.1 3661809 D 478434 CDS YP_003033326.1 253800325 8162140 3662276..3662944 1 NC_012943.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3662944 8162140 TBMG_03330 Mycobacterium tuberculosis KZN 1435 Maf-like protein YP_003033326.1 3662276 D 478434 CDS YP_003033327.1 253800326 8162141 3662913..3663878 1 NC_012943.1 thiosulfate sulfurtransferase sseA 3663878 8162141 TBMG_03331 Mycobacterium tuberculosis KZN 1435 thiosulfate sulfurtransferase sseA YP_003033327.1 3662913 D 478434 CDS YP_003033328.1 253800327 8162142 3663875..3664306 1 NC_012943.1 hypothetical protein 3664306 8162142 TBMG_03332 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033328.1 3663875 D 478434 CDS YP_003033329.1 253800328 8162143 3664414..3666216 1 NC_012943.1 bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 3666216 8162143 TBMG_03333 Mycobacterium tuberculosis KZN 1435 bifunctional acetyl-/propionyl-coenzyme A carboxylase subunit alpha accA3 YP_003033329.1 3664414 D 478434 CDS YP_003033330.1 253800329 8162144 complement(3666226..3667011) 1 NC_012943.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is a general stress response regulator; expressed in stationary phase and under nitrogen depletion and cold shock; RNA polymerase sigma factor SigF 3667011 8162144 TBMG_03334 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigF YP_003033330.1 3666226 R 478434 CDS YP_003033331.1 253800330 8162145 complement(3667008..3667634) 1 NC_012943.1 anti-sigma factor rsbW 3667634 8162145 TBMG_03335 Mycobacterium tuberculosis KZN 1435 anti-sigma factor rsbW YP_003033331.1 3667008 R 478434 CDS YP_003033332.1 253800331 8162146 complement(3667643..3668056) 1 NC_012943.1 hypothetical protein 3668056 8162146 TBMG_03336 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033332.1 3667643 R 478434 CDS YP_003033333.1 253800332 8162147 complement(3668091..3668468) 1 NC_012943.1 hypothetical protein 3668468 8162147 TBMG_03337 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033333.1 3668091 R 478434 CDS YP_003033334.1 253800333 8162148 complement(3668502..3669851) 1 NC_012943.1 catalyzes the formation of 2-aminoadipate 6-semiladehyde and glutamate from lysine and 2-oxoglutarate; L-lysine aminotransferase 3669851 8162148 TBMG_03338 Mycobacterium tuberculosis KZN 1435 L-lysine aminotransferase YP_003033334.1 3668502 R 478434 CDS YP_003033335.1 253800334 8162149 complement(3669902..3670354) 1 NC_012943.1 transcriptional regulator, asnC-family 3670354 8162149 TBMG_03339 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, asnC-family YP_003033335.1 3669902 R 478434 CDS YP_003033336.1 253800335 8162150 3670385..3671632 1 NC_012943.1 hypothetical protein 3671632 8162150 TBMG_03340 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033336.1 3670385 D 478434 CDS YP_003033337.1 253800336 8162151 3671659..3673143 1 NC_012943.1 piperideine-6-carboxilic acid dehydrogenase pcd 3673143 8162151 TBMG_03341 Mycobacterium tuberculosis KZN 1435 piperideine-6-carboxilic acid dehydrogenase pcd YP_003033337.1 3671659 D 478434 CDS YP_003033338.1 253800337 8162152 complement(3673243..3674052) 1 NC_012943.1 hypothetical protein 3674052 8162152 TBMG_03342 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033338.1 3673243 R 478434 CDS YP_003033339.1 253800338 8162153 3674123..3674788 1 NC_012943.1 TetR family transcriptional regulator 3674788 8162153 TBMG_03343 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033339.1 3674123 D 478434 CDS YP_003033340.1 253800339 8162154 3674832..3679373 1 NC_012943.1 ATP-dependent helicase lhr 3679373 8162154 TBMG_03344 Mycobacterium tuberculosis KZN 1435 ATP-dependent helicase lhr YP_003033340.1 3674832 D 478434 CDS YP_003033341.1 253800340 8162155 3679377..3680144 1 NC_012943.1 endonuclease VIII nei 3680144 8162155 TBMG_03345 Mycobacterium tuberculosis KZN 1435 endonuclease VIII nei YP_003033341.1 3679377 D 478434 CDS YP_003033342.1 253800341 8162156 complement(3680167..3681081) 1 NC_012943.1 esterase lipoprotein lpqC 3681081 8162156 TBMG_03346 Mycobacterium tuberculosis KZN 1435 esterase lipoprotein lpqC YP_003033342.1 3680167 R 478434 CDS YP_003033343.1 253800342 8162157 complement(3681108..3684020) 1 NC_012943.1 arylsulfatase 3684020 8162157 TBMG_03347 Mycobacterium tuberculosis KZN 1435 arylsulfatase YP_003033343.1 3681108 R 478434 CDS YP_003033344.1 253800343 8162158 complement(3684040..3684957) 1 NC_012943.1 hypothetical protein 3684957 8162158 TBMG_03348 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033344.1 3684040 R 478434 CDS YP_003033345.1 253800344 8162159 complement(3684969..3685634) 1 NC_012943.1 phosphate-transport system transcriptional regulator phoY1 3685634 8162159 TBMG_03349 Mycobacterium tuberculosis KZN 1435 phosphate-transport system transcriptional regulator phoY1 YP_003033345.1 3684969 R 478434 CDS YP_003033346.1 253800345 8162160 complement(3685742..3687499) 1 NC_012943.1 glycerol-3-phosphate dehydrogenase glpD2 3687499 8162160 TBMG_03350 Mycobacterium tuberculosis KZN 1435 glycerol-3-phosphate dehydrogenase glpD2 YP_003033346.1 3685742 R 478434 CDS YP_003033347.1 253800346 8162161 complement(3687580..3689025) 1 NC_012943.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase 3689025 8162161 TBMG_03351 Mycobacterium tuberculosis KZN 1435 flavoprotein disulfide reductase YP_003033347.1 3687580 R 478434 CDS YP_003033348.1 253800347 8162162 3689198..3689677 1 NC_012943.1 hypothetical protein 3689677 8162162 TBMG_03352 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033348.1 3689198 D 478434 CDS YP_003033349.1 253800348 8162163 complement(3689696..3690865) 1 NC_012943.1 N-acyl-L-amino acid amidohydrolase amiA1 3690865 8162163 TBMG_03353 Mycobacterium tuberculosis KZN 1435 N-acyl-L-amino acid amidohydrolase amiA1 YP_003033349.1 3689696 R 478434 CDS YP_003033350.1 253800349 8162164 complement(3690862..3692046) 1 NC_012943.1 amidohydrolase 3692046 8162164 TBMG_03354 Mycobacterium tuberculosis KZN 1435 amidohydrolase YP_003033350.1 3690862 R 478434 CDS YP_003033351.1 253800350 8162165 3692111..3692917 1 NC_012943.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 3692917 8162165 TBMG_03355 Mycobacterium tuberculosis KZN 1435 purine nucleoside phosphorylase YP_003033351.1 3692111 D 478434 CDS YP_003033352.1 253800351 8163143 3692921..3694525 1 NC_012943.1 phosphomannomutase pmmB 3694525 8163143 TBMG_03356 Mycobacterium tuberculosis KZN 1435 phosphomannomutase pmmB YP_003033352.1 3692921 D 478434 CDS YP_003033353.1 253800352 8163144 complement(3694527..3695150) 1 NC_012943.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 3695150 upp 8163144 upp Mycobacterium tuberculosis KZN 1435 uracil phosphoribosyltransferase YP_003033353.1 3694527 R 478434 CDS YP_003033354.1 253800353 8163145 3695255..3696154 1 NC_012943.1 acid phosphatase 3696154 8163145 TBMG_03358 Mycobacterium tuberculosis KZN 1435 acid phosphatase YP_003033354.1 3695255 D 478434 CDS YP_003033355.1 253800354 8163146 3696178..3697440 1 NC_012943.1 hypothetical protein 3697440 8163146 TBMG_03359 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033355.1 3696178 D 478434 CDS YP_003033356.1 253800355 8163147 complement(3697461..3698387) 1 NC_012943.1 hypothetical protein 3698387 8163147 TBMG_03360 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033356.1 3697461 R 478434 CDS YP_003033357.1 253800356 8163148 complement(3698413..3698583) 1 NC_012943.1 hypothetical protein 3698583 8163148 TBMG_04104 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033357.1 3698413 R 478434 CDS YP_003033358.1 253800357 8163149 complement(3698762..3699073) 1 NC_012943.1 secreted protein antigen 3699073 8163149 TBMG_03361 Mycobacterium tuberculosis KZN 1435 secreted protein antigen YP_003033358.1 3698762 R 478434 CDS YP_003033359.1 253800358 8163150 complement(3699144..3700241) 1 NC_012943.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 3700241 8163150 TBMG_03362 Mycobacterium tuberculosis KZN 1435 adenosine deaminase YP_003033359.1 3699144 R 478434 CDS YP_003033360.1 253800359 8163151 complement(3700241..3701524) 1 NC_012943.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 3701524 deoA 8163151 deoA Mycobacterium tuberculosis KZN 1435 thymidine phosphorylase YP_003033360.1 3700241 R 478434 CDS YP_003033361.1 253800360 8163152 complement(3701521..3702009) 1 NC_012943.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 3702009 8163152 TBMG_03364 Mycobacterium tuberculosis KZN 1435 cytidine deaminase YP_003033361.1 3701521 R 478434 CDS YP_003033362.1 253800361 8163153 3702063..3702497 1 NC_012943.1 succinate dehydrogenase cytochrome B-556 subunit sdhC 3702497 8163153 TBMG_03365 Mycobacterium tuberculosis KZN 1435 succinate dehydrogenase cytochrome B-556 subunit sdhC YP_003033362.1 3702063 D 478434 CDS YP_003033363.1 253800362 8163154 3702494..3702928 1 NC_012943.1 succinate dehydrogenase hydrophobic membrane anchor subunit sdhD 3702928 8163154 TBMG_03366 Mycobacterium tuberculosis KZN 1435 succinate dehydrogenase hydrophobic membrane anchor subunit sdhD YP_003033363.1 3702494 D 478434 CDS YP_003033364.1 253800363 8163155 3703057..3704829 1 NC_012943.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 3704829 sdhA 8163155 sdhA Mycobacterium tuberculosis KZN 1435 succinate dehydrogenase flavoprotein subunit YP_003033364.1 3703057 D 478434 CDS YP_003033365.1 253800364 8163156 3704829..3705620 1 NC_012943.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 3705620 sdhB 8163156 sdhB Mycobacterium tuberculosis KZN 1435 succinate dehydrogenase iron-sulfur subunit YP_003033365.1 3704829 D 478434 CDS YP_003033366.1 253800365 8163157 complement(3705699..3706127) 1 NC_012943.1 toxin 3706127 8163157 TBMG_03369 Mycobacterium tuberculosis KZN 1435 toxin YP_003033366.1 3705699 R 478434 CDS YP_003033367.1 253800366 8163158 complement(3706131..3706373) 1 NC_012943.1 antitoxin 3706373 8163158 TBMG_03370 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003033367.1 3706131 R 478434 CDS YP_003033368.1 253800367 8163159 complement(3706495..3707127) 1 NC_012943.1 methyltransferase 3707127 8163159 TBMG_03371 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003033368.1 3706495 R 478434 CDS YP_003033369.1 253800368 8163160 complement(3707106..3707771) 1 NC_012943.1 moaD-moaE fusion protein moaX 3707771 8163160 TBMG_03372 Mycobacterium tuberculosis KZN 1435 moaD-moaE fusion protein moaX YP_003033369.1 3707106 R 478434 CDS YP_003033370.1 253800369 8163161 complement(3707772..3708326) 1 NC_012943.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 3708326 moaC 8163161 moaC Mycobacterium tuberculosis KZN 1435 molybdenum cofactor biosynthesis protein MoaC YP_003033370.1 3707772 R 478434 CDS YP_003033371.1 253800370 8163162 complement(3708302..3708676) 1 NC_012943.1 pterin-4-alpha-carbinolamine dehydratase 3708676 8163162 TBMG_03374 Mycobacterium tuberculosis KZN 1435 pterin-4-alpha-carbinolamine dehydratase YP_003033371.1 3708302 R 478434 CDS YP_003033372.1 253800371 8163163 complement(3708737..3709621) 1 NC_012943.1 transposase 3709621 8163163 TBMG_03375 Mycobacterium tuberculosis KZN 1435 transposase YP_003033372.1 3708737 R 478434 CDS YP_003033373.1 253800372 8163164 complement(3709672..3709998) 1 NC_012943.1 transposase 3709998 8163164 TBMG_03376 Mycobacterium tuberculosis KZN 1435 transposase YP_003033373.1 3709672 R 478434 CDS YP_003033374.1 253800373 8163165 complement(3710047..3710250) 1 NC_012943.1 alternative RNA polymerase sigma factor sigJ 3710250 8163165 TBMG_03377 Mycobacterium tuberculosis KZN 1435 alternative RNA polymerase sigma factor sigJ YP_003033374.1 3710047 R 478434 CDS YP_003033375.1 253800374 8163166 3710301..3711617 1 NC_012943.1 hypothetical protein 3711617 8163166 TBMG_03378 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033375.1 3710301 D 478434 CDS YP_003033376.1 253800375 8163167 3711686..3712903 1 NC_012943.1 penicillin-binding protein dacB1 3712903 8163167 TBMG_03379 Mycobacterium tuberculosis KZN 1435 penicillin-binding protein dacB1 YP_003033376.1 3711686 D 478434 CDS YP_003033377.1 253800376 8163168 3712999..3714507 1 NC_012943.1 hypothetical protein 3714507 8163168 TBMG_03380 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033377.1 3712999 D 478434 CDS YP_003033378.1 253800377 8163169 3714504..3715655 1 NC_012943.1 N-acetylglucosamine-6-phosphate deacetylase nagA 3715655 8163169 TBMG_03381 Mycobacterium tuberculosis KZN 1435 N-acetylglucosamine-6-phosphate deacetylase nagA YP_003033378.1 3714504 D 478434 CDS YP_003033379.1 253800378 8163170 complement(3715846..3716691) 1 NC_012943.1 hypothetical protein 3716691 8163170 TBMG_03382 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033379.1 3715846 R 478434 CDS YP_003033380.1 253800379 8163172 3716668..3717147 1 NC_012943.1 hypothetical protein 3717147 8163172 TBMG_03383 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033380.1 3716668 D 478434 CDS YP_003033381.1 253800380 8163171 3717166..3717606 1 NC_012943.1 transcriptional regulator, merR-family 3717606 8163171 TBMG_03384 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, merR-family YP_003033381.1 3717166 D 478434 CDS YP_003033382.1 253800381 8163173 complement(3717640..3718509) 1 NC_012943.1 hypothetical protein 3718509 8163173 TBMG_03385 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033382.1 3717640 R 478434 CDS YP_003033383.1 253800382 8163174 complement(3718530..3719540) 1 NC_012943.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3719540 8163174 TBMG_03386 Mycobacterium tuberculosis KZN 1435 tryptophanyl-tRNA synthetase YP_003033383.1 3718530 R 478434 CDS YP_003033384.1 253800383 8163175 3719711..3720457 1 NC_012943.1 hypothetical protein 3720457 8163175 TBMG_03387 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033384.1 3719711 D 478434 CDS YP_003033385.1 253800384 8163176 complement(3720524..3721753) 1 NC_012943.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 3721753 8163176 TBMG_03388 Mycobacterium tuberculosis KZN 1435 isocitrate dehydrogenase YP_003033385.1 3720524 R 478434 CDS YP_003033386.1 253800385 8163177 3722036..3723385 1 NC_012943.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 3723385 8163177 TBMG_03389 Mycobacterium tuberculosis KZN 1435 O-acetylhomoserine aminocarboxypropyltransferase YP_003033386.1 3722036 D 478434 CDS YP_003033387.1 253800386 8163178 3723397..3724536 1 NC_012943.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 3724536 metX 8163178 metX Mycobacterium tuberculosis KZN 1435 homoserine O-acetyltransferase YP_003033387.1 3723397 D 478434 CDS YP_003033388.1 253800387 8163179 3724533..3725264 1 NC_012943.1 methyltransferase/methylase 3725264 8163179 TBMG_03391 Mycobacterium tuberculosis KZN 1435 methyltransferase/methylase YP_003033388.1 3724533 D 478434 CDS YP_003033389.1 253800388 8163180 complement(3725273..3732871) 1 NC_012943.1 PPE family protein 3732871 8163180 TBMG_03392 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033389.1 3725273 R 478434 CDS YP_003033390.1 253800389 8163181 complement(3732935..3733951) 1 NC_012943.1 PE-PGRS family protein 3733951 8163181 TBMG_04105 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033390.1 3732935 R 478434 CDS YP_003033391.1 253800390 8163182 complement(3734109..3738635) 1 NC_012943.1 hypothetical protein 3738635 8163182 TBMG_04106 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033391.1 3734109 R 478434 CDS YP_003033392.1 253800391 8163183 complement(3739059..3739316) 1 NC_012943.1 hypothetical protein 3739316 8163183 TBMG_03395 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033392.1 3739059 R 478434 CDS YP_003033393.1 253800392 8163184 complement(3739572..3749045) 1 NC_012943.1 PPE family protein 3749045 8163184 TBMG_03396 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033393.1 3739572 R 478434 CDS YP_003033394.1 253800393 8163185 complement(3749083..3749574) 1 NC_012943.1 hypothetical protein 3749574 8163185 TBMG_03397 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033394.1 3749083 R 478434 CDS YP_003033395.1 253800394 8163186 3749626..3750117 1 NC_012943.1 transposase 3750117 8163186 TBMG_03398 Mycobacterium tuberculosis KZN 1435 transposase YP_003033395.1 3749626 D 478434 CDS YP_003033396.1 253800395 8163187 complement(3750154..3751098) 1 NC_012943.1 transposase 3751098 8163187 TBMG_03399 Mycobacterium tuberculosis KZN 1435 transposase YP_003033396.1 3750154 R 478434 CDS YP_003033397.1 253800396 8163188 complement(3751189..3751425) 1 NC_012943.1 transposase 3751425 8163188 TBMG_03400 Mycobacterium tuberculosis KZN 1435 transposase YP_003033397.1 3751189 R 478434 CDS YP_003033398.1 253800397 8163189 complement(3751813..3763176) 1 NC_012943.1 PPE family protein 3763176 8163189 TBMG_03401 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033398.1 3751813 R 478434 CDS YP_003033399.1 253800398 8163190 complement(3763207..3764001) 1 NC_012943.1 oxidoreductase 3764001 8163190 TBMG_03402 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033399.1 3763207 R 478434 CDS YP_003033400.1 253800399 8163191 complement(3764083..3764454) 1 NC_012943.1 oxidoreductase 3764454 8163191 TBMG_03403 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033400.1 3764083 R 478434 CDS YP_003033401.1 253800400 8163192 complement(3764597..3764857) 1 NC_012943.1 oxidoreductase 3764857 8163192 TBMG_03404 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033401.1 3764597 R 478434 CDS YP_003033402.1 253800401 8163193 3764972..3765361 1 NC_012943.1 hypothetical protein 3765361 8163193 TBMG_03405 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033402.1 3764972 D 478434 CDS YP_003033403.1 253800402 8163194 complement(3765375..3765668) 1 NC_012943.1 hypothetical protein 3765668 8163194 TBMG_03406 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033403.1 3765375 R 478434 CDS YP_003033404.1 253800403 8163195 complement(3765665..3766510) 1 NC_012943.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3766510 8163195 TBMG_03407 Mycobacterium tuberculosis KZN 1435 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_003033404.1 3765665 R 478434 CDS YP_003033405.1 253800404 8163196 3766634..3766909 1 NC_012943.1 hypothetical protein 3766909 8163196 TBMG_03408 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033405.1 3766634 D 478434 CDS YP_003033406.1 253800405 8163197 3766906..3767163 1 NC_012943.1 hypothetical protein 3767163 8163197 TBMG_03409 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033406.1 3766906 D 478434 CDS YP_003033407.1 253800406 8163198 3767205..3768395 1 NC_012943.1 oxidoreductase 3768395 8163198 TBMG_03410 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033407.1 3767205 D 478434 CDS YP_003033408.1 253800407 8163199 3768512..3768880 1 NC_012943.1 hypothetical protein 3768880 8163199 TBMG_03411 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033408.1 3768512 D 478434 CDS YP_003033409.1 253800408 8163200 complement(3768877..3769428) 1 NC_012943.1 hypothetical protein 3769428 8163200 TBMG_03412 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033409.1 3768877 R 478434 CDS YP_003033410.1 253800409 8163201 complement(3769435..3770016) 1 NC_012943.1 ATP/GTP-binding protein 3770016 8163201 TBMG_03413 Mycobacterium tuberculosis KZN 1435 ATP/GTP-binding protein YP_003033410.1 3769435 R 478434 CDS YP_003033411.1 253800410 8163202 complement(3769997..3770365) 1 NC_012943.1 hypothetical protein 3770365 8163202 TBMG_03414 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033411.1 3769997 R 478434 CDS YP_003033412.1 253800411 8163203 complement(3770343..3770735) 1 NC_012943.1 hypothetical protein 3770735 8163203 TBMG_03415 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033412.1 3770343 R 478434 CDS YP_003033413.1 253800412 8163204 complement(3770732..3773362) 1 NC_012943.1 hypothetical protein 3773362 8163204 TBMG_03416 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033413.1 3770732 R 478434 CDS YP_003033414.1 253800413 8163205 3773598..3774062 1 NC_012943.1 tRNA/rRNA methylase spoU 3774062 8163205 TBMG_03417 Mycobacterium tuberculosis KZN 1435 tRNA/rRNA methylase spoU YP_003033414.1 3773598 D 478434 CDS YP_003033415.1 253800414 8163206 3774327..3776204 1 NC_012943.1 hypothetical protein 3776204 8163206 TBMG_03418 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033415.1 3774327 D 478434 CDS YP_003033416.1 253800415 8163207 complement(3776205..3776849) 1 NC_012943.1 oxidoreductase 3776849 8163207 TBMG_03419 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033416.1 3776205 R 478434 CDS YP_003033417.1 253800416 8163378 3776848..3777282 1 NC_012943.1 hypothetical protein 3777282 8163378 TBMG_03420 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033417.1 3776848 D 478434 CDS YP_003033418.1 253800417 8163208 complement(3777371..3780667) 1 NC_012943.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase 3780667 dnaE2 8163208 dnaE2 Mycobacterium tuberculosis KZN 1435 error-prone DNA polymerase YP_003033418.1 3777371 R 478434 CDS YP_003033419.1 253800418 8164323 3780802..3782142 1 NC_012943.1 hypothetical protein 3782142 8164323 TBMG_03422 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033419.1 3780802 D 478434 CDS YP_003033420.1 253800419 8164324 3782184..3783359 1 NC_012943.1 trehalose 6-phosphate phosphatase otsB2 3783359 8164324 TBMG_03423 Mycobacterium tuberculosis KZN 1435 trehalose 6-phosphate phosphatase otsB2 YP_003033420.1 3782184 D 478434 CDS YP_003033421.1 253800420 8164325 3783596..3784237 1 NC_012943.1 enoyl-CoA hydratase echA18 3784237 8164325 TBMG_03424 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase echA18 YP_003033421.1 3783596 D 478434 CDS YP_003033422.1 253800421 8164326 3784238..3784486 1 NC_012943.1 enoyl-CoA hydratase echA18_1 3784486 8164326 TBMG_03425 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase echA18_1 YP_003033422.1 3784238 D 478434 CDS YP_003033423.1 253800422 8164327 3784491..3785918 1 NC_012943.1 amidase 3785918 8164327 TBMG_03426 Mycobacterium tuberculosis KZN 1435 amidase YP_003033423.1 3784491 D 478434 CDS YP_003033424.1 253800423 8164328 3786026..3786679 1 NC_012943.1 hypothetical protein 3786679 8164328 TBMG_03427 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033424.1 3786026 D 478434 CDS YP_003033425.1 253800424 8164329 complement(3786718..3788223) 1 NC_012943.1 cyclase 3788223 8164329 TBMG_03428 Mycobacterium tuberculosis KZN 1435 cyclase YP_003033425.1 3786718 R 478434 CDS YP_003033426.1 253800425 8164330 complement(3788228..3789118) 1 NC_012943.1 hypothetical protein 3789118 8164330 TBMG_03429 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033426.1 3788228 R 478434 CDS YP_003033427.1 253800426 8164331 complement(3789127..3790737) 1 NC_012943.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3790737 8164331 TBMG_04107 Mycobacterium tuberculosis KZN 1435 1-deoxy-D-xylulose-5-phosphate synthase YP_003033427.1 3789127 R 478434 CDS YP_003033428.1 253800427 8164332 complement(3790682..3790963) 1 NC_012943.1 1-deoxy-D-xylulose-5-phosphate synthase 3790963 8164332 TBMG_04108 Mycobacterium tuberculosis KZN 1435 1-deoxy-D-xylulose-5-phosphate synthase YP_003033428.1 3790682 R 478434 CDS YP_003033429.1 253800428 8164333 complement(3790960..3791955) 1 NC_012943.1 lytB-related protein lytB1 3791955 8164333 TBMG_03431 Mycobacterium tuberculosis KZN 1435 lytB-related protein lytB1 YP_003033429.1 3790960 R 478434 CDS YP_003033430.1 253800429 8164334 complement(3791949..3793001) 1 NC_012943.1 polyprenyl synthetase 3793001 8164334 TBMG_03432 Mycobacterium tuberculosis KZN 1435 polyprenyl synthetase YP_003033430.1 3791949 R 478434 CDS YP_003033431.1 253800430 8164335 complement(3793755..3794147) 1 NC_012943.1 toxin 3794147 8164335 TBMG_03433 Mycobacterium tuberculosis KZN 1435 toxin YP_003033431.1 3793755 R 478434 CDS YP_003033432.1 253800431 8164336 complement(3794147..3794455) 1 NC_012943.1 antitoxin 3794455 8164336 TBMG_03434 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003033432.1 3794147 R 478434 CDS YP_003033433.1 253800432 8164337 3794529..3795308 1 NC_012943.1 transposase 3795308 8164337 TBMG_03435 Mycobacterium tuberculosis KZN 1435 transposase YP_003033433.1 3794529 D 478434 CDS YP_003033434.1 253800433 8164338 3795235..3795975 1 NC_012943.1 transposase 3795975 8164338 TBMG_03436 Mycobacterium tuberculosis KZN 1435 transposase YP_003033434.1 3795235 D 478434 CDS YP_003033435.1 253800434 8164339 3796165..3798360 1 NC_012943.1 PE-PGRS family protein 3798360 8164339 TBMG_04109 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033435.1 3796165 D 478434 CDS YP_003033436.1 253800435 8164340 complement(3798431..3799303) 1 NC_012943.1 dehydrogenase 3799303 8164340 TBMG_03439 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003033436.1 3798431 R 478434 CDS YP_003033437.1 253800436 8164341 3799377..3800087 1 NC_012943.1 hypothetical protein 3800087 8164341 TBMG_03440 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033437.1 3799377 D 478434 CDS YP_003033438.1 253800437 8164342 3800133..3802085 1 NC_012943.1 short chain dehydrogenase 3802085 8164342 TBMG_03441 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033438.1 3800133 D 478434 CDS YP_003033439.1 253800438 8164343 complement(3802086..3802949) 1 NC_012943.1 cyclopropane-fatty-acyl-phospholipid synthase 1 cmaA1 3802949 8164343 TBMG_03442 Mycobacterium tuberculosis KZN 1435 cyclopropane-fatty-acyl-phospholipid synthase 1 cmaA1 YP_003033439.1 3802086 R 478434 CDS YP_003033440.1 253800439 8164344 3802973..3803899 1 NC_012943.1 nucleoside hydrolase iunH 3803899 8164344 TBMG_03443 Mycobacterium tuberculosis KZN 1435 nucleoside hydrolase iunH YP_003033440.1 3802973 D 478434 CDS YP_003033441.1 253800440 8164345 complement(3803954..3805537) 1 NC_012943.1 hypothetical protein 3805537 8164345 TBMG_03444 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033441.1 3803954 R 478434 CDS YP_003033442.1 253800441 8164346 complement(3805534..3806148) 1 NC_012943.1 hypothetical protein 3806148 8164346 TBMG_03445 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033442.1 3805534 R 478434 CDS YP_003033443.1 253800442 8164348 3806147..3806857 1 NC_012943.1 hypothetical protein 3806857 8164348 TBMG_03446 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033443.1 3806147 D 478434 CDS YP_003033444.1 253800443 8164347 complement(3807013..3808590) 1 NC_012943.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 3808590 guaA 8164347 guaA Mycobacterium tuberculosis KZN 1435 GMP synthase YP_003033444.1 3807013 R 478434 CDS YP_003033445.1 253800444 8164349 complement(3808602..3809510) 1 NC_012943.1 phytoene synthase 3809510 8164349 TBMG_03448 Mycobacterium tuberculosis KZN 1435 phytoene synthase YP_003033445.1 3808602 R 478434 CDS YP_003033446.1 253800445 8164350 complement(3809539..3810618) 1 NC_012943.1 multifunctional geranylgeranyl pyrophosphate synthetase idsA1 3810618 8164350 TBMG_03449 Mycobacterium tuberculosis KZN 1435 multifunctional geranylgeranyl pyrophosphate synthetase idsA1 YP_003033446.1 3809539 R 478434 CDS YP_003033447.1 253800446 8164351 3810641..3811687 1 NC_012943.1 hypothetical protein 3811687 8164351 TBMG_03450 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033447.1 3810641 D 478434 CDS YP_003033448.1 253800447 8164352 3811751..3812539 1 NC_012943.1 hydrolase 3812539 8164352 TBMG_03451 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003033448.1 3811751 D 478434 CDS YP_003033449.1 253800448 8164353 3812554..3814914 1 NC_012943.1 hypothetical protein 3814914 8164353 TBMG_03452 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033449.1 3812554 D 478434 CDS YP_003033450.1 253800449 8164354 complement(3815397..3816635) 1 NC_012943.1 hypothetical protein 3816635 8164354 TBMG_03453 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033450.1 3815397 R 478434 CDS YP_003033451.1 253800450 8164355 complement(3817006..3818607) 1 NC_012943.1 hypothetical protein 3818607 8164355 TBMG_03454 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033451.1 3817006 R 478434 CDS YP_003033452.1 253800451 8164356 complement(3818624..3819328) 1 NC_012943.1 hypothetical protein 3819328 8164356 TBMG_03455 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033452.1 3818624 R 478434 CDS YP_003033453.1 253800452 8164357 complement(3819446..3820012) 1 NC_012943.1 transcriptional regulator 3820012 8164357 TBMG_03456 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003033453.1 3819446 R 478434 CDS YP_003033454.1 253800453 8164358 3820074..3820961 1 NC_012943.1 dioxygenase 3820961 8164358 TBMG_03457 Mycobacterium tuberculosis KZN 1435 dioxygenase YP_003033454.1 3820074 D 478434 CDS YP_003033455.1 253800454 8164359 3820996..3821295 1 NC_012943.1 antitoxin 3821295 8164359 TBMG_03458 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003033455.1 3820996 D 478434 CDS YP_003033456.1 253800455 8164360 3821292..3821702 1 NC_012943.1 toxin 3821702 8164360 TBMG_03459 Mycobacterium tuberculosis KZN 1435 toxin YP_003033456.1 3821292 D 478434 CDS YP_003033457.1 253800456 8164361 complement(3821735..3823471) 1 NC_012943.1 cholesterol oxidase precursor choD 3823471 8164361 TBMG_03460 Mycobacterium tuberculosis KZN 1435 cholesterol oxidase precursor choD YP_003033457.1 3821735 R 478434 CDS YP_003033458.1 253800457 8164362 complement(3823527..3824654) 1 NC_012943.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 3824654 8164362 TBMG_03461 Mycobacterium tuberculosis KZN 1435 inosine 5-monophosphate dehydrogenase YP_003033458.1 3823527 R 478434 CDS YP_003033459.1 253800458 8164363 complement(3824674..3826263) 1 NC_012943.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 3826263 8164363 TBMG_03462 Mycobacterium tuberculosis KZN 1435 inosine 5'-monophosphate dehydrogenase YP_003033459.1 3824674 R 478434 CDS YP_003033460.1 253800459 8164364 3826470..3826880 1 NC_012943.1 hypothetical protein 3826880 8164364 TBMG_03463 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033460.1 3826470 D 478434 CDS YP_003033461.1 253800460 8164365 complement(3826890..3827789) 1 NC_012943.1 hypothetical protein 3827789 8164365 TBMG_03464 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033461.1 3826890 R 478434 CDS YP_003033462.1 253800461 8164366 complement(3827782..3828420) 1 NC_012943.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase; RNA polymerase sigma factor SigD 3828420 8164366 TBMG_03465 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigD YP_003033462.1 3827782 R 478434 CDS YP_003033463.1 253800462 8164367 complement(3828378..3829229) 1 NC_012943.1 hypothetical protein 3829229 8164367 TBMG_03466 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033463.1 3828378 R 478434 CDS YP_003033464.1 253800463 8164368 3829636..3829944 1 NC_012943.1 transcriptional regulator whib-like whiB3 3829944 8164368 TBMG_03467 Mycobacterium tuberculosis KZN 1435 transcriptional regulator whib-like whiB3 YP_003033464.1 3829636 D 478434 CDS YP_003033465.1 253800464 8164369 complement(3830016..3831635) 1 NC_012943.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; molecular chaperone GroEL 3831635 groEL 8164369 groEL Mycobacterium tuberculosis KZN 1435 molecular chaperone GroEL YP_003033465.1 3830016 R 478434 CDS YP_003033466.1 253800465 8164370 complement(3831730..3832032) 1 NC_012943.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 3832032 groES 8164370 groES Mycobacterium tuberculosis KZN 1435 co-chaperonin GroES YP_003033466.1 3831730 R 478434 CDS YP_003033467.1 253800466 8164371 complement(3832299..3833333) 1 NC_012943.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3833333 8164371 TBMG_03470 Mycobacterium tuberculosis KZN 1435 DNA-binding/iron metalloprotein/AP endonuclease YP_003033467.1 3832299 R 478434 CDS YP_003033468.1 253800467 8164372 complement(3833330..3833812) 1 NC_012943.1 ribosomal-protein-alanine acetyltransferase rimI 3833812 8164372 TBMG_03471 Mycobacterium tuberculosis KZN 1435 ribosomal-protein-alanine acetyltransferase rimI YP_003033468.1 3833330 R 478434 CDS YP_003033469.1 253800468 8164373 complement(3833803..3834450) 1 NC_012943.1 hypothetical protein 3834450 8164373 TBMG_03472 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033469.1 3833803 R 478434 CDS YP_003033470.1 253800469 8164374 complement(3834435..3834941) 1 NC_012943.1 hypothetical protein 3834941 8164374 TBMG_03473 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033470.1 3834435 R 478434 CDS YP_003033471.1 253800470 8164375 complement(3834938..3836164) 1 NC_012943.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 3836164 alr 8164375 alr Mycobacterium tuberculosis KZN 1435 alanine racemase YP_003033471.1 3834938 R 478434 CDS YP_003033472.1 253800471 8164376 complement(3836458..3836820) 1 NC_012943.1 hypothetical protein 3836820 8164376 TBMG_03475 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033472.1 3836458 R 478434 CDS YP_003033473.1 253800472 8164377 3836983..3837519 1 NC_012943.1 PPE family protein 3837519 8164377 TBMG_03476 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033473.1 3836983 D 478434 CDS YP_003033474.1 253800473 8164378 complement(3837460..3838623) 1 NC_012943.1 transposase 3838623 8164378 TBMG_03477 Mycobacterium tuberculosis KZN 1435 transposase YP_003033474.1 3837460 R 478434 CDS YP_003033475.1 253800474 8164379 complement(3838662..3838817) 1 NC_012943.1 hypothetical protein 3838817 8164379 TBMG_04110 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033475.1 3838662 R 478434 CDS YP_003033476.1 253800475 8164380 complement(3838842..3839051) 1 NC_012943.1 hypothetical protein 3839051 8164380 TBMG_03478 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033476.1 3838842 R 478434 CDS YP_003033477.1 253800476 8164381 complement(3839112..3839957) 1 NC_012943.1 transposase 3839957 8164381 TBMG_03479 Mycobacterium tuberculosis KZN 1435 transposase YP_003033477.1 3839112 R 478434 CDS YP_003033478.1 253800477 8164382 complement(3840190..3841572) 1 NC_012943.1 glutamate decarboxylase gadB 3841572 8164382 TBMG_03480 Mycobacterium tuberculosis KZN 1435 glutamate decarboxylase gadB YP_003033478.1 3840190 R 478434 CDS YP_003033479.1 253800478 8164383 complement(3841610..3843031) 1 NC_012943.1 hypothetical protein 3843031 8164383 TBMG_03481 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033479.1 3841610 R 478434 CDS YP_003033480.1 253800479 8164384 complement(3843033..3843746) 1 NC_012943.1 hypothetical protein 3843746 8164384 TBMG_03482 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033480.1 3843033 R 478434 CDS YP_003033481.1 253800480 8164385 complement(3843757..3844695) 1 NC_012943.1 hypothetical protein 3844695 8164385 TBMG_03483 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033481.1 3843757 R 478434 CDS YP_003033482.1 253800481 8164386 complement(3844833..3846707) 1 NC_012943.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 3846707 8164386 TBMG_03484 Mycobacterium tuberculosis KZN 1435 glucosamine--fructose-6-phosphate aminotransferase YP_003033482.1 3844833 R 478434 CDS YP_003033483.1 253800482 8164387 3846729..3847205 1 NC_012943.1 hypothetical protein 3847205 8164387 TBMG_03485 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033483.1 3846729 D 478434 CDS YP_003033484.1 253800483 8164388 3847215..3848057 1 NC_012943.1 hypothetical protein 3848057 8164388 TBMG_03486 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033484.1 3847215 D 478434 CDS YP_003033485.1 253800484 8164389 complement(3848077..3849480) 1 NC_012943.1 hypothetical protein 3849480 8164389 TBMG_03487 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033485.1 3848077 R 478434 CDS YP_003033486.1 253800485 8164390 complement(3849483..3849794) 1 NC_012943.1 hypothetical protein 3849794 8164390 TBMG_03488 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033486.1 3849483 R 478434 CDS YP_003033487.1 253800486 8164391 complement(3849842..3851188) 1 NC_012943.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3851188 glmM 8164391 glmM Mycobacterium tuberculosis KZN 1435 phosphoglucosamine mutase YP_003033487.1 3849842 R 478434 CDS YP_003033488.1 253800487 8164392 complement(3851313..3851768) 1 NC_012943.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3851768 rpsI 8164392 rpsI Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S9 YP_003033488.1 3851313 R 478434 CDS YP_003033489.1 253800488 8164393 complement(3851765..3852208) 1 NC_012943.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3852208 rplM 8164393 rplM Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L13 YP_003033489.1 3851765 R 478434 CDS YP_003033490.1 253800489 8164394 complement(3852441..3852743) 1 NC_012943.1 esat-6 like protein esxT 3852743 8164394 TBMG_03492 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxT YP_003033490.1 3852441 R 478434 CDS YP_003033491.1 253800490 8164395 complement(3852764..3853141) 1 NC_012943.1 esat-6 like protein esxU 3853141 8164395 TBMG_03493 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxU YP_003033491.1 3852764 R 478434 CDS YP_003033492.1 253800491 8164396 complement(3853134..3854348) 1 NC_012943.1 hypothetical protein 3854348 8164396 TBMG_03494 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033492.1 3853134 R 478434 CDS YP_003033493.1 253800492 8164397 complement(3854345..3858055) 1 NC_012943.1 hypothetical protein 3858055 8164397 TBMG_03495 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033493.1 3854345 R 478434 CDS YP_003033494.1 253800493 8164398 3858169..3859572 1 NC_012943.1 hypothetical protein 3859572 8164398 TBMG_03496 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033494.1 3858169 D 478434 CDS YP_003033495.1 253800494 8164399 3859569..3860936 1 NC_012943.1 membrane-anchored mycosin mycP4 3860936 8164399 TBMG_03497 Mycobacterium tuberculosis KZN 1435 membrane-anchored mycosin mycP4 YP_003033495.1 3859569 D 478434 CDS YP_003033496.1 253800495 8164400 complement(3860901..3862349) 1 NC_012943.1 hypothetical protein 3862349 8164400 TBMG_03498 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033496.1 3860901 R 478434 CDS YP_003033497.1 253800496 8164401 3862434..3863222 1 NC_012943.1 cutinase precursor cut3 3863222 8164401 TBMG_03499 Mycobacterium tuberculosis KZN 1435 cutinase precursor cut3 YP_003033497.1 3862434 D 478434 CDS YP_003033498.1 253800497 8164402 3863254..3863949 1 NC_012943.1 cutinase precursor cut4 3863949 8164402 TBMG_03500 Mycobacterium tuberculosis KZN 1435 cutinase precursor cut4 YP_003033498.1 3863254 D 478434 CDS YP_003033499.1 253800498 8164403 3864221..3864553 1 NC_012943.1 hypothetical protein 3864553 8164403 TBMG_03501 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033499.1 3864221 D 478434 CDS YP_003033500.1 253800499 8164321 3864576..3865907 1 NC_012943.1 hypothetical protein 3865907 8164321 TBMG_03502 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033500.1 3864576 D 478434 CDS YP_003033501.1 253800500 8161731 complement(3865869..3866762) 1 NC_012943.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 3866762 truA 8161731 truA Mycobacterium tuberculosis KZN 1435 tRNA pseudouridine synthase A YP_003033501.1 3865869 R 478434 CDS YP_003033502.1 253800501 8161732 complement(3866707..3867249) 1 NC_012943.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3867249 rplQ 8161732 rplQ Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L17 YP_003033502.1 3866707 R 478434 CDS YP_003033503.1 253800502 8161733 complement(3867281..3868324) 1 NC_012943.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3868324 8161733 TBMG_03505 Mycobacterium tuberculosis KZN 1435 DNA-directed RNA polymerase subunit alpha YP_003033503.1 3867281 R 478434 CDS YP_003033504.1 253800503 8161734 complement(3868476..3869081) 1 NC_012943.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3869081 rpsD 8161734 rpsD Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S4 YP_003033504.1 3868476 R 478434 CDS YP_003033505.1 253800504 8161735 complement(3869090..3869509) 1 NC_012943.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3869509 8161735 TBMG_03507 Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S11 YP_003033505.1 3869090 R 478434 CDS YP_003033506.1 253800505 8161736 complement(3869513..3869887) 1 NC_012943.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3869887 rpsM 8161736 rpsM Mycobacterium tuberculosis KZN 1435 30S ribosomal protein S13 YP_003033506.1 3869513 R 478434 CDS YP_003033507.1 253800506 8161737 complement(3870103..3870216) 1 NC_012943.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3870216 rpmJ 8161737 rpmJ Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L36 YP_003033507.1 3870103 R 478434 CDS YP_003033508.1 253800507 8161738 complement(3870249..3870470) 1 NC_012943.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 3870470 infA 8161738 infA Mycobacterium tuberculosis KZN 1435 translation initiation factor IF-1 YP_003033508.1 3870249 R 478434 CDS YP_003033509.1 253800508 8161739 3870724..3871581 1 NC_012943.1 hypothetical protein 3871581 8161739 TBMG_03511 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033509.1 3870724 D 478434 CDS YP_003033510.1 253800509 8161740 3871654..3872649 1 NC_012943.1 dTDP-glucose 4,6-dehydratase rmlB 3872649 8161740 TBMG_03512 Mycobacterium tuberculosis KZN 1435 dTDP-glucose 4,6-dehydratase rmlB YP_003033510.1 3871654 D 478434 CDS YP_003033511.1 253800510 8161741 3872651..3873259 1 NC_012943.1 dTDP-4-dehydrorhamnose 3,5-epimerase rmlC 3873259 8161741 TBMG_03513 Mycobacterium tuberculosis KZN 1435 dTDP-4-dehydrorhamnose 3,5-epimerase rmlC YP_003033511.1 3872651 D 478434 CDS YP_003033512.1 253800511 8161742 3873342..3874010 1 NC_012943.1 hypothetical protein 3874010 8161742 TBMG_03514 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033512.1 3873342 D 478434 CDS YP_003033513.1 253800512 8161743 3873871..3874734 1 NC_012943.1 hypothetical protein 3874734 8161743 TBMG_03515 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033513.1 3873871 D 478434 CDS YP_003033514.1 253800513 8161744 complement(3874792..3875886) 1 NC_012943.1 dTDP-glucose-4,6-dehydratase 3875886 8161744 TBMG_03516 Mycobacterium tuberculosis KZN 1435 dTDP-glucose-4,6-dehydratase YP_003033514.1 3874792 R 478434 CDS YP_003033515.1 253800514 8161745 complement(3875890..3876900) 1 NC_012943.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 3876900 8161745 TBMG_03517 Mycobacterium tuberculosis KZN 1435 4-hydroxy-2-ketovalerate aldolase YP_003033515.1 3875890 R 478434 CDS YP_003033516.1 253800515 8161746 complement(3876961..3878634) 1 NC_012943.1 acetolactate synthase large subunit ilvB2 3878634 8161746 TBMG_03518 Mycobacterium tuberculosis KZN 1435 acetolactate synthase large subunit ilvB2 YP_003033516.1 3876961 R 478434 CDS YP_003033517.1 253800516 8161747 complement(3878625..3879158) 1 NC_012943.1 hypothetical protein 3879158 8161747 TBMG_03519 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033517.1 3878625 R 478434 CDS YP_003033518.1 253800517 8161748 3879179..3879685 1 NC_012943.1 hypothetical protein 3879685 8161748 TBMG_03520 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033518.1 3879179 D 478434 CDS YP_003033519.1 253800518 8161749 complement(3879765..3880634) 1 NC_012943.1 peroxidase bpoA 3880634 8161749 TBMG_03521 Mycobacterium tuberculosis KZN 1435 peroxidase bpoA YP_003033519.1 3879765 R 478434 CDS YP_003033520.1 253800519 8161750 complement(3880830..3882179) 1 NC_012943.1 hypothetical protein 3882179 8161750 TBMG_03522 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033520.1 3880830 R 478434 CDS YP_003033521.1 253800520 8161751 3882552..3882848 1 NC_012943.1 PE family protein 3882848 8161751 TBMG_03523 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003033521.1 3882552 D 478434 CDS YP_003033522.1 253800521 8161752 3882885..3884066 1 NC_012943.1 PPE family protein 3884066 8161752 TBMG_03524 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033522.1 3882885 D 478434 CDS YP_003033523.1 253800522 8161753 3884096..3887344 1 NC_012943.1 hypothetical protein 3887344 8161753 TBMG_03525 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033523.1 3884096 D 478434 CDS YP_003033524.1 253800523 8161754 complement(3887368..3888861) 1 NC_012943.1 hypothetical protein 3888861 8161754 TBMG_03526 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033524.1 3887368 R 478434 CDS YP_003033525.1 253800524 8161755 complement(3888952..3889698) 1 NC_012943.1 hypothetical protein 3889698 8161755 TBMG_03527 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033525.1 3888952 R 478434 CDS YP_003033526.1 253800525 8161756 complement(3889783..3890565) 1 NC_012943.1 hypothetical protein 3890565 8161756 TBMG_03528 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033526.1 3889783 R 478434 CDS YP_003033527.1 253800526 8161757 complement(3890609..3891271) 1 NC_012943.1 hypothetical protein 3891271 8161757 TBMG_03529 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033527.1 3890609 R 478434 CDS YP_003033528.1 253800527 8161758 3891537..3893075 1 NC_012943.1 hypothetical protein 3893075 8161758 TBMG_03530 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033528.1 3891537 D 478434 CDS YP_003033529.1 253800528 8161759 complement(3893081..3894025) 1 NC_012943.1 short chain dehydrogenase 3894025 8161759 TBMG_03531 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033529.1 3893081 R 478434 CDS YP_003033530.1 253800529 8161760 3894231..3894680 1 NC_012943.1 hypothetical protein 3894680 8161760 TBMG_03532 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033530.1 3894231 D 478434 CDS YP_003033531.1 253800530 8161761 complement(3894633..3895466) 1 NC_012943.1 esterase/lipase lipF 3895466 8161761 TBMG_03533 Mycobacterium tuberculosis KZN 1435 esterase/lipase lipF YP_003033531.1 3894633 R 478434 CDS YP_003033532.1 253800531 8161762 3896126..3896449 1 NC_012943.1 hypothetical protein 3896449 8161762 TBMG_03534 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033532.1 3896126 D 478434 CDS YP_003033533.1 253800532 8161763 3896695..3898197 1 NC_012943.1 alpha, alpha-trehalose-phosphate synthase otsA 3898197 8161763 TBMG_03535 Mycobacterium tuberculosis KZN 1435 alpha, alpha-trehalose-phosphate synthase otsA YP_003033533.1 3896695 D 478434 CDS YP_003033534.1 253800533 8161764 3898349..3898927 1 NC_012943.1 hypothetical protein 3898927 8161764 TBMG_03536 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033534.1 3898349 D 478434 CDS YP_003033535.1 253800534 8161765 complement(3898924..3899406) 1 NC_012943.1 MCE-associated protein 3899406 8161765 TBMG_03537 Mycobacterium tuberculosis KZN 1435 MCE-associated protein YP_003033535.1 3898924 R 478434 CDS YP_003033536.1 253800535 8161766 complement(3899406..3900134) 1 NC_012943.1 hypothetical protein 3900134 8161766 TBMG_03538 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033536.1 3899406 R 478434 CDS YP_003033537.1 253800536 8161767 complement(3900134..3901828) 1 NC_012943.1 MCE-family protein mce4F 3901828 8161767 TBMG_03539 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce4F YP_003033537.1 3900134 R 478434 CDS YP_003033538.1 253800537 8161768 complement(3901839..3902993) 1 NC_012943.1 MCE-family lipoprotein mce4E 3902993 8161768 TBMG_03540 Mycobacterium tuberculosis KZN 1435 MCE-family lipoprotein mce4E YP_003033538.1 3901839 R 478434 CDS YP_003033539.1 253800538 8161769 complement(3902990..3904345) 1 NC_012943.1 MCE-family protein mce4D 3904345 8161769 TBMG_03541 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce4D YP_003033539.1 3902990 R 478434 CDS YP_003033540.1 253800539 8161770 complement(3904342..3905415) 1 NC_012943.1 MCE-family protein mce4C 3905415 8161770 TBMG_03542 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce4C YP_003033540.1 3904342 R 478434 CDS YP_003033541.1 253800540 8161771 complement(3905405..3906457) 1 NC_012943.1 MCE-family protein mce4B 3906457 8161771 TBMG_03543 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce4B YP_003033541.1 3905405 R 478434 CDS YP_003033542.1 253800541 8161772 complement(3906457..3907659) 1 NC_012943.1 MCE-family protein mce4A 3907659 8161772 TBMG_03544 Mycobacterium tuberculosis KZN 1435 MCE-family protein mce4A YP_003033542.1 3906457 R 478434 CDS YP_003033543.1 253800542 8161773 complement(3907679..3908521) 1 NC_012943.1 hypothetical protein 3908521 8161773 TBMG_03545 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033543.1 3907679 R 478434 CDS YP_003033544.1 253800543 8161774 complement(3908556..3909320) 1 NC_012943.1 hypothetical protein 3909320 8161774 TBMG_03546 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033544.1 3908556 R 478434 CDS YP_003033545.1 253800544 8161775 complement(3909546..3910499) 1 NC_012943.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 3910499 fabG 8161775 fabG Mycobacterium tuberculosis KZN 1435 3-ketoacyl-ACP reductase YP_003033545.1 3909546 R 478434 CDS YP_003033546.1 253800545 8161776 complement(3910524..3910715) 1 NC_012943.1 ferredoxin fdxD 3910715 8161776 TBMG_03548 Mycobacterium tuberculosis KZN 1435 ferredoxin fdxD YP_003033546.1 3910524 R 478434 CDS YP_003033547.1 253800546 8161777 3910930..3912132 1 NC_012943.1 acyl-CoA dehydrogenase 3912132 8161777 TBMG_03549 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033547.1 3910930 D 478434 CDS YP_003033548.1 253800547 8161778 3912157..3913278 1 NC_012943.1 acyl-CoA dehydrogenase 3913278 8161778 TBMG_03550 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033548.1 3912157 D 478434 CDS YP_003033549.1 253800548 8161779 3913349..3914857 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3914857 8161779 TBMG_03551 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003033549.1 3913349 D 478434 CDS YP_003033550.1 253800549 8161780 3915028..3919239 1 NC_012943.1 PE-PGRS family protein 3919239 8161780 TBMG_03552 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033550.1 3915028 D 478434 CDS YP_003033551.1 253800550 8161781 3919530..3923975 1 NC_012943.1 hypothetical protein 3923975 8161781 TBMG_04111 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033551.1 3919530 D 478434 CDS YP_003033552.1 253800551 8161782 complement(3924142..3925689) 1 NC_012943.1 thiamine-pyrophosphate requiring enzyme; hypothetical protein 3925689 8161782 TBMG_04112 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033552.1 3924142 R 478434 CDS YP_003033553.1 253800552 8161783 complement(3925686..3926522) 1 NC_012943.1 hypothetical protein 3926522 8161783 TBMG_04113 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033553.1 3925686 R 478434 CDS YP_003033554.1 253800553 8161784 3926882..3932185 1 NC_012943.1 hypothetical protein 3932185 8161784 TBMG_04114 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033554.1 3926882 D 478434 CDS YP_003033555.1 253800554 8161785 complement(3932314..3932970) 1 NC_012943.1 fatty-acid-CoA ligase fadD18 3932970 8161785 TBMG_04115 Mycobacterium tuberculosis KZN 1435 fatty-acid-CoA ligase fadD18 YP_003033555.1 3932314 R 478434 CDS YP_003033556.1 253800555 8161786 3933016..3935736 1 NC_012943.1 hypothetical protein 3935736 8161786 TBMG_03553 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033556.1 3933016 D 478434 CDS YP_003033557.1 253800556 8161787 complement(3936297..3937943) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; acyl-CoA synthetase 3937943 8161787 TBMG_03554 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003033557.1 3936297 R 478434 CDS YP_003033558.1 253800557 8161788 3938017..3938808 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3938808 8161788 TBMG_03555 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003033558.1 3938017 D 478434 CDS YP_003033559.1 253800558 8161789 3938904..3939743 1 NC_012943.1 hypothetical protein 3939743 8161789 TBMG_03556 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033559.1 3938904 D 478434 CDS YP_003033560.1 253800559 8161790 complement(3939798..3940994) 1 NC_012943.1 cytochrome P450 monooxygenase 142 cyp142 3940994 8161790 TBMG_03557 Mycobacterium tuberculosis KZN 1435 cytochrome P450 monooxygenase 142 cyp142 YP_003033560.1 3939798 R 478434 CDS YP_003033561.1 253800560 8161791 3941023..3941733 1 NC_012943.1 hypothetical protein 3941733 8161791 TBMG_03558 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033561.1 3941023 D 478434 CDS YP_003033562.1 253800561 8161792 complement(3941798..3942841) 1 NC_012943.1 coenzyme F420-dependent oxidoreductase 3942841 8161792 TBMG_03559 Mycobacterium tuberculosis KZN 1435 coenzyme F420-dependent oxidoreductase YP_003033562.1 3941798 R 478434 CDS YP_003033563.1 253800562 8161793 3942901..3943905 1 NC_012943.1 hypothetical protein 3943905 8161793 TBMG_03560 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033563.1 3942901 D 478434 CDS YP_003033564.1 253800563 8161794 3943921..3944985 1 NC_012943.1 lipid-transfer protein 3944985 8161794 TBMG_03561 Mycobacterium tuberculosis KZN 1435 lipid-transfer protein YP_003033564.1 3943921 D 478434 CDS YP_003033565.1 253800564 8161795 3945002..3946186 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3946186 8161795 TBMG_03562 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003033565.1 3945002 D 478434 CDS YP_003033566.1 253800565 8161796 3946228..3947259 1 NC_012943.1 hypothetical protein 3947259 8161796 TBMG_03563 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033566.1 3946228 D 478434 CDS YP_003033567.1 253800566 8161797 complement(3947273..3947797) 1 NC_012943.1 siderophore-binding protein 3947797 8161797 TBMG_03564 Mycobacterium tuberculosis KZN 1435 siderophore-binding protein YP_003033567.1 3947273 R 478434 CDS YP_003033568.1 253800567 8161798 3947912..3949072 1 NC_012943.1 oxidoreductase 3949072 8161798 TBMG_03565 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033568.1 3947912 D 478434 CDS YP_003033569.1 253800568 8161799 3949078..3949527 1 NC_012943.1 hypothetical protein 3949527 8161799 TBMG_03566 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033569.1 3949078 D 478434 CDS YP_003033570.1 253800569 8161800 complement(3949952..3950665) 1 NC_012943.1 hypothetical protein 3950665 8161800 TBMG_03567 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033570.1 3949952 R 478434 CDS YP_003033571.1 253800570 8161801 complement(3951357..3952511) 1 NC_012943.1 hypothetical protein 3952511 8161801 TBMG_03568 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033571.1 3951357 R 478434 CDS YP_003033572.1 253800571 8161802 complement(3952511..3953293) 1 NC_012943.1 short chain dehydrogenase 3953293 8161802 TBMG_03569 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033572.1 3952511 R 478434 CDS YP_003033573.1 253800572 8161803 complement(3953290..3954417) 1 NC_012943.1 hypothetical protein 3954417 8161803 TBMG_04116 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033573.1 3953290 R 478434 CDS YP_003033574.1 253800573 8161804 3954816..3956036 1 NC_012943.1 PPE family protein 3956036 8161804 TBMG_03572 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033574.1 3954816 D 478434 CDS YP_003033575.1 253800574 8161805 complement(3956178..3957926) 1 NC_012943.1 PPE family protein 3957926 8161805 TBMG_03573 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033575.1 3956178 R 478434 CDS YP_003033576.1 253800575 8161806 complement(3958025..3959065) 1 NC_012943.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 3959065 8161806 TBMG_03574 Mycobacterium tuberculosis KZN 1435 4-hydroxy-2-ketovalerate aldolase YP_003033576.1 3958025 R 478434 CDS YP_003033577.1 253800576 8161807 complement(3959062..3959973) 1 NC_012943.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 3959973 8161807 TBMG_03575 Mycobacterium tuberculosis KZN 1435 acetaldehyde dehydrogenase YP_003033577.1 3959062 R 478434 CDS YP_003033578.1 253800577 8161808 complement(3959984..3960769) 1 NC_012943.1 hydratase 3960769 8161808 TBMG_03576 Mycobacterium tuberculosis KZN 1435 hydratase YP_003033578.1 3959984 R 478434 CDS YP_003033579.1 253800578 8161485 3960833..3962533 1 NC_012943.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 3962533 8161485 TBMG_03577 Mycobacterium tuberculosis KZN 1435 3-ketosteroid-delta-1-dehydrogenase YP_003033579.1 3960833 D 478434 CDS YP_003033580.1 253800579 8161568 3962535..3963395 1 NC_012943.1 dehydrogenase 3963395 8161568 TBMG_03578 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003033580.1 3962535 D 478434 CDS YP_003033581.1 253800580 8161569 3963532..3964971 1 NC_012943.1 PPE family protein 3964971 8161569 TBMG_03579 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033581.1 3963532 D 478434 CDS YP_003033582.1 253800581 8161570 complement(3964972..3966132) 1 NC_012943.1 lipid-transfer protein 3966132 8161570 TBMG_03580 Mycobacterium tuberculosis KZN 1435 lipid-transfer protein YP_003033582.1 3964972 R 478434 CDS YP_003033583.1 253800582 8161571 complement(3966132..3966521) 1 NC_012943.1 hypothetical protein 3966521 8161571 TBMG_03581 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033583.1 3966132 R 478434 CDS YP_003033584.1 253800583 8161572 complement(3966518..3967453) 1 NC_012943.1 hypothetical protein 3967453 8161572 TBMG_03582 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033584.1 3966518 R 478434 CDS YP_003033585.1 253800584 8161573 complement(3967450..3968613) 1 NC_012943.1 acyl-CoA dehydrogenase 3968613 8161573 TBMG_03583 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033585.1 3967450 R 478434 CDS YP_003033586.1 253800585 8161574 complement(3968598..3969635) 1 NC_012943.1 acyl-CoA dehydrogenase 3969635 8161574 TBMG_04117 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033586.1 3968598 R 478434 CDS YP_003033587.1 253800586 8161575 complement(3969617..3970918) 1 NC_012943.1 cytochrome P450 125 cyp125 3970918 8161575 TBMG_03584 Mycobacterium tuberculosis KZN 1435 cytochrome P450 125 cyp125 YP_003033587.1 3969617 R 478434 CDS YP_003033588.1 253800587 8161576 3971030..3972205 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3972205 8161576 TBMG_03585 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003033588.1 3971030 D 478434 CDS YP_003033589.1 253800588 8161577 3972317..3972772 1 NC_012943.1 hypothetical protein 3972772 8161577 TBMG_03586 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033589.1 3972317 D 478434 CDS YP_003033590.1 253800589 8161578 complement(3972855..3973769) 1 NC_012943.1 short chain dehydrogenase 3973769 8161578 TBMG_03587 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033590.1 3972855 R 478434 CDS YP_003033591.1 253800590 8161579 complement(3973792..3974571) 1 NC_012943.1 short chain dehydrogenase 3974571 8161579 TBMG_03588 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033591.1 3973792 R 478434 CDS YP_003033592.1 253800591 8161580 3974626..3975369 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3975369 8161580 TBMG_03589 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003033592.1 3974626 D 478434 CDS YP_003033593.1 253800592 8161581 3975369..3976247 1 NC_012943.1 CoA-transferase alpha subunit 3976247 8161581 TBMG_03590 Mycobacterium tuberculosis KZN 1435 CoA-transferase alpha subunit YP_003033593.1 3975369 D 478434 CDS YP_003033594.1 253800593 8161582 3976244..3976996 1 NC_012943.1 CoA-transferase beta subunit 3976996 8161582 TBMG_03591 Mycobacterium tuberculosis KZN 1435 CoA-transferase beta subunit YP_003033594.1 3976244 D 478434 CDS YP_003033595.1 253800594 8161583 3977094..3978161 1 NC_012943.1 oxidoreductase 3978161 8161583 TBMG_03592 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033595.1 3977094 D 478434 CDS YP_003033596.1 253800595 8161584 3978158..3980215 1 NC_012943.1 electron transfer protein fdxB 3980215 8161584 TBMG_03593 Mycobacterium tuberculosis KZN 1435 electron transfer protein fdxB YP_003033596.1 3978158 D 478434 CDS YP_003033597.1 253800596 8161585 complement(3980303..3981172) 1 NC_012943.1 hypothetical protein 3981172 8161585 TBMG_03594 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033597.1 3980303 R 478434 CDS YP_003033598.1 253800597 8161586 complement(3981277..3982437) 1 NC_012943.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3982437 8161586 TBMG_03595 Mycobacterium tuberculosis KZN 1435 acetyl-CoA acetyltransferase YP_003033598.1 3981277 R 478434 CDS YP_003033599.1 253800598 8161587 complement(3982502..3983104) 1 NC_012943.1 TetR family transcriptional regulator 3983104 8161587 TBMG_03596 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033599.1 3982502 R 478434 CDS YP_003033600.1 253800599 8161588 3983213..3985108 1 NC_012943.1 PPE family protein 3985108 8161588 TBMG_03597 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033600.1 3983213 D 478434 CDS YP_003033601.1 253800600 8161589 complement(3985117..3985905) 1 NC_012943.1 short chain dehydrogenase 3985905 8161589 TBMG_03598 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033601.1 3985117 R 478434 CDS YP_003033602.1 253800601 8161590 complement(3985902..3987059) 1 NC_012943.1 acyl-CoA dehydrogenase 3987059 8161590 TBMG_03599 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033602.1 3985902 R 478434 CDS YP_003033603.1 253800602 8161591 3987107..3988630 1 NC_012943.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 3988630 8161591 TBMG_03600 Mycobacterium tuberculosis KZN 1435 long-chain-fatty-acid--CoA ligase YP_003033603.1 3987107 D 478434 CDS YP_003033604.1 253800603 8161592 3988631..3989764 1 NC_012943.1 acyl-CoA dehydrogenase 3989764 8161592 TBMG_03601 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033604.1 3988631 D 478434 CDS YP_003033605.1 253800604 8161593 3989761..3990720 1 NC_012943.1 acyl-CoA dehydrogenase 3990720 8161593 TBMG_03602 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033605.1 3989761 D 478434 CDS YP_003033606.1 253800605 8161594 3990717..3991673 1 NC_012943.1 acyl-CoA dehydrogenase 3991673 8161594 TBMG_03603 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033606.1 3990717 D 478434 CDS YP_003033607.1 253800606 8161595 3991670..3992836 1 NC_012943.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 3992836 8161595 TBMG_03604 Mycobacterium tuberculosis KZN 1435 aspartate aminotransferase YP_003033607.1 3991670 D 478434 CDS YP_003033608.1 253800607 8161596 complement(3992801..3994189) 1 NC_012943.1 arylamine N-acetyltransferase nat 3994189 8161596 TBMG_03605 Mycobacterium tuberculosis KZN 1435 arylamine N-acetyltransferase nat YP_003033608.1 3992801 R 478434 CDS YP_003033609.1 253800608 8161597 complement(3994189..3994752) 1 NC_012943.1 oxidoreductase 3994752 8161597 TBMG_03606 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033609.1 3994189 R 478434 CDS YP_003033610.1 253800609 8161598 complement(3994767..3995669) 1 NC_012943.1 biphenyl-2,3-diol 1,2-dioxygenase bphC 3995669 8161598 TBMG_03607 Mycobacterium tuberculosis KZN 1435 biphenyl-2,3-diol 1,2-dioxygenase bphC YP_003033610.1 3994767 R 478434 CDS YP_003033611.1 253800610 8161599 complement(3995666..3996541) 1 NC_012943.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3996541 8161599 TBMG_03608 Mycobacterium tuberculosis KZN 1435 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase YP_003033611.1 3995666 R 478434 CDS YP_003033612.1 253800611 8161600 complement(3996556..3997740) 1 NC_012943.1 oxidoreductase 3997740 8161600 TBMG_03609 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033612.1 3996556 R 478434 CDS YP_003033613.1 253800612 8161601 3997887..3998963 1 NC_012943.1 hemoglobine-related protein hmp 3998963 8161601 TBMG_03610 Mycobacterium tuberculosis KZN 1435 hemoglobine-related protein hmp YP_003033613.1 3997887 D 478434 CDS YP_003033614.1 253800613 8161602 3998981..3999511 1 NC_012943.1 hypothetical protein 3999511 8161602 TBMG_03611 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033614.1 3998981 D 478434 CDS YP_003033615.1 253800614 8161603 complement(3999547..4001682) 1 NC_012943.1 acyl-CoA dehydrogenase 4001682 8161603 TBMG_03612 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033615.1 3999547 R 478434 CDS YP_003033616.1 253800615 8161605 4001666..4002553 1 NC_012943.1 TetR family transcriptional regulator 4002553 8161605 TBMG_03613 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033616.1 4001666 D 478434 CDS YP_003033617.1 253800616 8161604 complement(4002559..4003773) 1 NC_012943.1 transcriptional regulator, laci-family 4003773 8161604 TBMG_03614 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, laci-family YP_003033617.1 4002559 R 478434 CDS YP_003033618.1 253800617 8161606 4003828..4004541 1 NC_012943.1 hypothetical protein 4004541 8161606 TBMG_03615 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033618.1 4003828 D 478434 CDS YP_003033619.1 253800618 8161607 4004678..4005598 1 NC_012943.1 hypothetical protein 4005598 8161607 TBMG_03616 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033619.1 4004678 D 478434 CDS YP_003033620.1 253800619 8161608 4005612..4006853 1 NC_012943.1 hypothetical protein 4006853 8161608 TBMG_03617 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033620.1 4005612 D 478434 CDS YP_003033621.1 253800620 8161609 complement(4006895..4007863) 1 NC_012943.1 tRNA/rRNA methyltransferase 4007863 8161609 TBMG_03618 Mycobacterium tuberculosis KZN 1435 tRNA/rRNA methyltransferase YP_003033621.1 4006895 R 478434 CDS YP_003033622.1 253800621 8161610 complement(4007864..4009273) 1 NC_012943.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 4009273 cysS 8161610 cysS Mycobacterium tuberculosis KZN 1435 cysteinyl-tRNA synthetase YP_003033622.1 4007864 R 478434 CDS YP_003033623.1 253800622 8161611 complement(4009338..4009817) 1 NC_012943.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4009817 ispF 8161611 ispF Mycobacterium tuberculosis KZN 1435 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_003033623.1 4009338 R 478434 CDS YP_003033624.1 253800623 8161612 complement(4009814..4010509) 1 NC_012943.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4010509 ispD 8161612 ispD Mycobacterium tuberculosis KZN 1435 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_003033624.1 4009814 R 478434 CDS YP_003033625.1 253800624 8161613 complement(4010526..4011014) 1 NC_012943.1 transcriptional regulator 4011014 8161613 TBMG_03622 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003033625.1 4010526 R 478434 CDS YP_003033626.1 253800625 8161614 4011300..4011848 1 NC_012943.1 hypothetical protein 4011848 8161614 TBMG_03623 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033626.1 4011300 D 478434 CDS YP_003033627.1 253800626 8161615 4011914..4013356 1 NC_012943.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4013356 8161615 TBMG_03624 Mycobacterium tuberculosis KZN 1435 DNA repair protein RadA YP_003033627.1 4011914 D 478434 CDS YP_003033628.1 253800627 8161616 4013361..4014437 1 NC_012943.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 4014437 8161616 TBMG_03625 Mycobacterium tuberculosis KZN 1435 DNA integrity scanning protein DisA YP_003033628.1 4013361 D 478434 CDS YP_003033629.1 253800628 8161617 complement(4014438..4015256) 1 NC_012943.1 hypothetical protein 4015256 8161617 TBMG_03626 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033629.1 4014438 R 478434 CDS YP_003033630.1 253800629 8161618 complement(4015341..4015964) 1 NC_012943.1 carbonic anhydrase 4015964 8161618 TBMG_03627 Mycobacterium tuberculosis KZN 1435 carbonic anhydrase YP_003033630.1 4015341 R 478434 CDS YP_003033631.1 253800630 8161620 4015963..4016877 1 NC_012943.1 adenine glycosylase mutY 4016877 8161620 TBMG_03628 Mycobacterium tuberculosis KZN 1435 adenine glycosylase mutY YP_003033631.1 4015963 D 478434 CDS YP_003033632.1 253800631 8161619 complement(4016874..4018628) 1 NC_012943.1 PE-PGRS family protein 4018628 8161619 TBMG_03629 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033632.1 4016874 R 478434 CDS YP_003033633.1 253800632 8161621 complement(4018739..4019512) 1 NC_012943.1 hydrolase 4019512 8161621 TBMG_03630 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003033633.1 4018739 R 478434 CDS YP_003033634.1 253800633 8161622 4019527..4019844 1 NC_012943.1 hypothetical protein 4019844 8161622 TBMG_03631 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033634.1 4019527 D 478434 CDS YP_003033635.1 253800634 8161623 4019822..4021180 1 NC_012943.1 hypothetical protein 4021180 8161623 TBMG_03632 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033635.1 4019822 D 478434 CDS YP_003033636.1 253800635 8161624 4021327..4022154 1 NC_012943.1 hypothetical protein 4022154 8161624 TBMG_03633 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033636.1 4021327 D 478434 CDS YP_003033637.1 253800636 8161625 complement(4022201..4023520) 1 NC_012943.1 PE-PGRS family protein 4023520 8161625 TBMG_03634 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033637.1 4022201 R 478434 CDS YP_003033638.1 253800637 8161626 complement(4023628..4026174) 1 NC_012943.1 ATP-dependent protease ATP-binding subunit clpC1 4026174 8161626 TBMG_03635 Mycobacterium tuberculosis KZN 1435 ATP-dependent protease ATP-binding subunit clpC1 YP_003033638.1 4023628 R 478434 CDS YP_003033639.1 253800638 8161627 complement(4026451..4026789) 1 NC_012943.1 iron-regulated lsr2 protein precursor 4026789 8161627 TBMG_03636 Mycobacterium tuberculosis KZN 1435 iron-regulated lsr2 protein precursor YP_003033639.1 4026451 R 478434 CDS YP_003033640.1 253800639 8161628 complement(4026893..4028410) 1 NC_012943.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4028410 lysS 8161628 lysS Mycobacterium tuberculosis KZN 1435 lysyl-tRNA synthetase YP_003033640.1 4026893 R 478434 CDS YP_003033641.1 253800640 8161629 complement(4028511..4029329) 1 NC_012943.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 4029329 8161629 TBMG_03638 Mycobacterium tuberculosis KZN 1435 pantothenate kinase YP_003033641.1 4028511 R 478434 CDS YP_003033642.1 253800641 8161630 complement(4029332..4029751) 1 NC_012943.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 4029751 8161630 TBMG_03639 Mycobacterium tuberculosis KZN 1435 aspartate alpha-decarboxylase YP_003033642.1 4029332 R 478434 CDS YP_003033643.1 253800642 8161631 complement(4029751..4030680) 1 NC_012943.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 4030680 panC 8161631 panC Mycobacterium tuberculosis KZN 1435 pantoate--beta-alanine ligase YP_003033643.1 4029751 R 478434 CDS YP_003033644.1 253800643 8161632 complement(4030677..4031651) 1 NC_012943.1 hypothetical protein 4031651 8161632 TBMG_03641 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033644.1 4030677 R 478434 CDS YP_003033645.1 253800644 8161633 complement(4031773..4032966) 1 NC_012943.1 hypothetical protein 4032966 8161633 TBMG_03642 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033645.1 4031773 R 478434 CDS YP_003033646.1 253800645 8161634 complement(4033175..4033651) 1 NC_012943.1 hypothetical protein 4033651 8161634 TBMG_03643 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033646.1 4033175 R 478434 CDS YP_003033647.1 253800646 8161635 complement(4033651..4034217) 1 NC_012943.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 4034217 8161635 TBMG_03644 Mycobacterium tuberculosis KZN 1435 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_003033647.1 4033651 R 478434 CDS YP_003033648.1 253800647 8161636 complement(4034214..4034615) 1 NC_012943.1 dihydroneopterin aldolase folB 4034615 8161636 TBMG_03645 Mycobacterium tuberculosis KZN 1435 dihydroneopterin aldolase folB YP_003033648.1 4034214 R 478434 CDS YP_003033649.1 253800648 8161637 complement(4034608..4035450) 1 NC_012943.1 dihydropteroate synthase 1 folp 4035450 8161637 TBMG_03646 Mycobacterium tuberculosis KZN 1435 dihydropteroate synthase 1 folp YP_003033649.1 4034608 R 478434 CDS YP_003033650.1 253800649 8161638 complement(4035447..4036055) 1 NC_012943.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 4036055 folE 8161638 folE Mycobacterium tuberculosis KZN 1435 GTP cyclohydrolase I YP_003033650.1 4035447 R 478434 CDS YP_003033651.1 253800650 8161639 complement(4036071..4038353) 1 NC_012943.1 membrane-bound ell division protein ftsH 4038353 8161639 TBMG_03648 Mycobacterium tuberculosis KZN 1435 membrane-bound ell division protein ftsH YP_003033651.1 4036071 R 478434 CDS YP_003033652.1 253800651 8161640 complement(4038877..4039206) 1 NC_012943.1 hypothetical protein 4039206 8161640 TBMG_03650 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033652.1 4038877 R 478434 CDS YP_003033653.1 253800652 8161641 complement(4039501..4040055) 1 NC_012943.1 hypothetical protein 4040055 8161641 TBMG_03651 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033653.1 4039501 R 478434 CDS YP_003033654.1 253800653 8161642 complement(4040171..4040482) 1 NC_012943.1 hypothetical protein 4040482 8161642 TBMG_03652 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033654.1 4040171 R 478434 CDS YP_003033655.1 253800654 8161643 complement(4040556..4041734) 1 NC_012943.1 hypothetical protein 4041734 8161643 TBMG_03653 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033655.1 4040556 R 478434 CDS YP_003033656.1 253800655 8161644 4043092..4044060 1 NC_012943.1 epoxide hydrolase ephA 4044060 8161644 TBMG_03654 Mycobacterium tuberculosis KZN 1435 epoxide hydrolase ephA YP_003033656.1 4043092 D 478434 CDS YP_003033657.1 253800656 8161645 4044057..4045244 1 NC_012943.1 monooxygenase 4045244 8161645 TBMG_03655 Mycobacterium tuberculosis KZN 1435 monooxygenase YP_003033657.1 4044057 D 478434 CDS YP_003033658.1 253800657 8161646 complement(4045343..4045627) 1 NC_012943.1 esat-6 like protein esxV 4045627 8161646 TBMG_03656 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxV YP_003033658.1 4045343 R 478434 CDS YP_003033659.1 253800658 8161647 complement(4045654..4045950) 1 NC_012943.1 esat-6 like protein esxW 4045950 8161647 TBMG_03657 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxW YP_003033659.1 4045654 R 478434 CDS YP_003033660.1 253800659 8161648 complement(4046007..4047248) 1 NC_012943.1 PPE family protein 4047248 8161648 TBMG_03658 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033660.1 4046007 R 478434 CDS YP_003033661.1 253800660 8163892 complement(4047258..4047557) 1 NC_012943.1 PE family protein 4047557 8163892 TBMG_03659 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003033661.1 4047258 R 478434 CDS YP_003033662.1 253800661 8163893 4047808..4048608 1 NC_012943.1 hypothetical protein 4048608 8163893 TBMG_03660 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033662.1 4047808 D 478434 CDS YP_003033663.1 253800662 8163894 complement(4048613..4049263) 1 NC_012943.1 hypoxanthine-guanine phosphoribosyltransferase hpt 4049263 8163894 TBMG_03661 Mycobacterium tuberculosis KZN 1435 hypoxanthine-guanine phosphoribosyltransferase hpt YP_003033663.1 4048613 R 478434 CDS YP_003033664.1 253800663 8163895 complement(4049260..4050231) 1 NC_012943.1 cell cycle protein mesJ 4050231 8163895 TBMG_03662 Mycobacterium tuberculosis KZN 1435 cell cycle protein mesJ YP_003033664.1 4049260 R 478434 CDS YP_003033665.1 253800664 8163896 complement(4050210..4051271) 1 NC_012943.1 hypothetical protein 4051271 8163896 TBMG_03663 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033665.1 4050210 R 478434 CDS YP_003033666.1 253800665 8163897 complement(4051259..4052644) 1 NC_012943.1 hypothetical protein 4052644 8163897 TBMG_03664 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033666.1 4051259 R 478434 CDS YP_003033667.1 253800666 8163898 4052782..4053270 1 NC_012943.1 inorganic pyrophosphatase ppa 4053270 8163898 TBMG_03665 Mycobacterium tuberculosis KZN 1435 inorganic pyrophosphatase ppa YP_003033667.1 4052782 D 478434 CDS YP_003033668.1 253800667 8163899 complement(4053316..4054413) 1 NC_012943.1 hypothetical protein 4054413 8163899 TBMG_03666 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033668.1 4053316 R 478434 CDS YP_003033669.1 253800668 8163900 4054534..4055829 1 NC_012943.1 hypothetical protein 4055829 8163900 TBMG_03667 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033669.1 4054534 D 478434 CDS YP_003033670.1 253800669 8163901 4055873..4056598 1 NC_012943.1 transferase 4056598 8163901 TBMG_03668 Mycobacterium tuberculosis KZN 1435 transferase YP_003033670.1 4055873 D 478434 CDS YP_003033671.1 253800670 8163902 4056595..4056939 1 NC_012943.1 hypothetical protein 4056939 8163902 TBMG_03669 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033671.1 4056595 D 478434 CDS YP_003033672.1 253800671 8163903 4057150..4058025 1 NC_012943.1 hypothetical protein 4058025 8163903 TBMG_03670 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033672.1 4057150 D 478434 CDS YP_003033673.1 253800672 8163904 complement(4058026..4058994) 1 NC_012943.1 UDP-glucose 4-epimerase galE1 4058994 8163904 TBMG_03671 Mycobacterium tuberculosis KZN 1435 UDP-glucose 4-epimerase galE1 YP_003033673.1 4058026 R 478434 CDS YP_003033674.1 253800673 8163906 4058993..4060768 1 NC_012943.1 hypothetical protein 4060768 8163906 TBMG_03672 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033674.1 4058993 D 478434 CDS YP_003033675.1 253800674 8163905 4061111..4061458 1 NC_012943.1 transposase 4061458 8163905 TBMG_03673 Mycobacterium tuberculosis KZN 1435 transposase YP_003033675.1 4061111 D 478434 CDS YP_003033676.1 253800675 8163907 4061843..4062343 1 NC_012943.1 transposase 4062343 8163907 TBMG_03674 Mycobacterium tuberculosis KZN 1435 transposase YP_003033676.1 4061843 D 478434 CDS YP_003033677.1 253800676 8163908 4062343..4063089 1 NC_012943.1 transposase 4063089 8163908 TBMG_03675 Mycobacterium tuberculosis KZN 1435 transposase YP_003033677.1 4062343 D 478434 CDS YP_003033678.1 253800677 8163909 complement(4063263..4064147) 1 NC_012943.1 transposase 4064147 8163909 TBMG_03676 Mycobacterium tuberculosis KZN 1435 transposase YP_003033678.1 4063263 R 478434 CDS YP_003033679.1 253800678 8163910 complement(4064198..4064524) 1 NC_012943.1 transposase 4064524 8163910 TBMG_03677 Mycobacterium tuberculosis KZN 1435 transposase YP_003033679.1 4064198 R 478434 CDS YP_003033680.1 253800679 8163911 complement(4064601..4065167) 1 NC_012943.1 hypothetical protein 4065167 8163911 TBMG_03678 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033680.1 4064601 R 478434 CDS YP_003033681.1 253800680 8163912 complement(4065237..4066466) 1 NC_012943.1 transposase 4066466 8163912 TBMG_03679 Mycobacterium tuberculosis KZN 1435 transposase YP_003033681.1 4065237 R 478434 CDS YP_003033682.1 253800681 8163913 complement(4066642..4067277) 1 NC_012943.1 cell filamentation protein fic 4067277 8163913 TBMG_03680 Mycobacterium tuberculosis KZN 1435 cell filamentation protein fic YP_003033682.1 4066642 R 478434 CDS YP_003033683.1 253800682 8163914 complement(4067288..4067482) 1 NC_012943.1 hypothetical protein 4067482 8163914 TBMG_03681 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033683.1 4067288 R 478434 CDS YP_003033684.1 253800683 8163915 4067877..4068068 1 NC_012943.1 hypothetical protein 4068068 8163915 TBMG_03682 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033684.1 4067877 D 478434 CDS YP_003033685.1 253800684 8163917 complement(4068233..4069441) 1 NC_012943.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 4069441 8163917 TBMG_03683 Mycobacterium tuberculosis KZN 1435 DNA polymerase III subunit delta' YP_003033685.1 4068233 R 478434 CDS YP_003033686.1 253800685 8161400 4069524..4071173 1 NC_012943.1 hypothetical protein 4071173 8161400 TBMG_03684 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033686.1 4069524 D 478434 CDS YP_003033687.1 253800686 8161401 complement(4071170..4073974) 1 NC_012943.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 4073974 8161401 TBMG_03685 Mycobacterium tuberculosis KZN 1435 DNA topoisomerase I YP_003033687.1 4071170 R 478434 CDS YP_003033688.1 253800687 8164496 complement(4074327..4074905) 1 NC_012943.1 hypothetical protein 4074905 8164496 TBMG_03686 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033688.1 4074327 R 478434 CDS YP_003033689.1 253800688 8164497 complement(4075045..4075248) 1 NC_012943.1 cold shock protein A cspA 4075248 8164497 TBMG_03687 Mycobacterium tuberculosis KZN 1435 cold shock protein A cspA YP_003033689.1 4075045 R 478434 CDS YP_003033690.1 253800689 8164498 4075498..4077813 1 NC_012943.1 helicase 4077813 8164498 TBMG_03688 Mycobacterium tuberculosis KZN 1435 helicase YP_003033690.1 4075498 D 478434 CDS YP_003033691.1 253800690 8164499 4077950..4078234 1 NC_012943.1 PE family protein 4078234 8164499 TBMG_03689 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003033691.1 4077950 D 478434 CDS YP_003033692.1 253800691 8164500 4078558..4079595 1 NC_012943.1 hypothetical protein 4079595 8164500 TBMG_03690 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033692.1 4078558 D 478434 CDS YP_003033693.1 253800692 8164501 complement(4080110..4080355) 1 NC_012943.1 hypothetical protein 4080355 8164501 TBMG_03691 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033693.1 4080110 R 478434 CDS YP_003033694.1 253800693 8164503 4080342..4080662 1 NC_012943.1 PE-PGRS family protein 4080662 8164503 TBMG_03692 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033694.1 4080342 D 478434 CDS YP_003033695.1 253800694 8164502 4080656..4081243 1 NC_012943.1 PE-PGRS family protein 4081243 8164502 TBMG_03693 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033695.1 4080656 D 478434 CDS YP_003033696.1 253800695 8164504 complement(4081376..4081699) 1 NC_012943.1 hypothetical protein 4081699 8164504 TBMG_03694 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033696.1 4081376 R 478434 CDS YP_003033697.1 253800696 8164505 complement(4081716..4082015) 1 NC_012943.1 hypothetical protein 4082015 8164505 TBMG_03695 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033697.1 4081716 R 478434 CDS YP_003033698.1 253800697 8164506 complement(4082039..4082245) 1 NC_012943.1 hypothetical protein 4082245 8164506 TBMG_03696 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033698.1 4082039 R 478434 CDS YP_003033699.1 253800698 8164507 complement(4082255..4082830) 1 NC_012943.1 hypothetical protein 4082830 8164507 TBMG_03697 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033699.1 4082255 R 478434 CDS YP_003033700.1 253800699 8164508 complement(4082854..4083654) 1 NC_012943.1 hypothetical protein 4083654 8164508 TBMG_03698 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033700.1 4082854 R 478434 CDS YP_003033701.1 253800700 8164509 complement(4083651..4084814) 1 NC_012943.1 hypothetical protein 4084814 8164509 TBMG_03699 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033701.1 4083651 R 478434 CDS YP_003033702.1 253800701 8164510 complement(4084811..4085884) 1 NC_012943.1 hypothetical protein 4085884 8164510 TBMG_03700 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033702.1 4084811 R 478434 CDS YP_003033703.1 253800702 8164511 4086362..4087225 1 NC_012943.1 hypothetical protein 4087225 8164511 TBMG_03701 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033703.1 4086362 D 478434 CDS YP_003033704.1 253800703 8164512 complement(4087980..4088750) 1 NC_012943.1 hypothetical protein 4088750 8164512 TBMG_03702 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033704.1 4087980 R 478434 CDS YP_003033705.1 253800704 8164513 complement(4088747..4090393) 1 NC_012943.1 dipeptide-transport ATP-binding protein ABC transporter dppD 4090393 8164513 TBMG_03703 Mycobacterium tuberculosis KZN 1435 dipeptide-transport ATP-binding protein ABC transporter dppD YP_003033705.1 4088747 R 478434 CDS YP_003033706.1 253800705 8164514 complement(4090390..4091253) 1 NC_012943.1 hypothetical protein 4091253 8164514 TBMG_03704 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033706.1 4090390 R 478434 CDS YP_003033707.1 253800706 8164515 complement(4091246..4092172) 1 NC_012943.1 hypothetical protein 4092172 8164515 TBMG_03705 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033707.1 4091246 R 478434 CDS YP_003033708.1 253800707 8164516 complement(4092174..4093799) 1 NC_012943.1 periplasmic dipeptide-binding lipoprotein dppA 4093799 8164516 TBMG_03706 Mycobacterium tuberculosis KZN 1435 periplasmic dipeptide-binding lipoprotein dppA YP_003033708.1 4092174 R 478434 CDS YP_003033709.1 253800708 8164517 4093885..4094241 1 NC_012943.1 hypothetical protein 4094241 8164517 TBMG_03707 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033709.1 4093885 D 478434 CDS YP_003033710.1 253800709 8164518 4094190..4094384 1 NC_012943.1 hypothetical protein 4094384 8164518 TBMG_03708 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033710.1 4094190 D 478434 CDS YP_003033711.1 253800710 8164519 4094507..4096462 1 NC_012943.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4096462 8164519 TBMG_03709 Mycobacterium tuberculosis KZN 1435 acetyl-CoA synthetase YP_003033711.1 4094507 D 478434 CDS YP_003033712.1 253800711 8164520 complement(4096498..4097196) 1 NC_012943.1 protease 4097196 8164520 TBMG_03710 Mycobacterium tuberculosis KZN 1435 protease YP_003033712.1 4096498 R 478434 CDS YP_003033713.1 253800712 8164521 4097542..4098060 1 NC_012943.1 hypothetical protein 4098060 8164521 TBMG_03711 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033713.1 4097542 D 478434 CDS YP_003033714.1 253800713 8161402 4098061..4099044 1 NC_012943.1 epoxide hydrolase ephE 4099044 8161402 TBMG_03712 Mycobacterium tuberculosis KZN 1435 epoxide hydrolase ephE YP_003033714.1 4098061 D 478434 CDS YP_003033715.1 253800714 8164523 complement(4099037..4100230) 1 NC_012943.1 membrane-associated serine protease 4100230 8164523 TBMG_03713 Mycobacterium tuberculosis KZN 1435 membrane-associated serine protease YP_003033715.1 4099037 R 478434 CDS YP_003033716.1 253800715 8164524 complement(4100236..4101057) 1 NC_012943.1 hypothetical protein 4101057 8164524 TBMG_03714 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033716.1 4100236 R 478434 CDS YP_003033717.1 253800716 8164525 complement(4101189..4101872) 1 NC_012943.1 membrane-anchored thioredoxin 4101872 8164525 TBMG_03715 Mycobacterium tuberculosis KZN 1435 membrane-anchored thioredoxin YP_003033717.1 4101189 R 478434 CDS YP_003033718.1 253800717 8164526 complement(4101872..4102609) 1 NC_012943.1 endonuclease III nth 4102609 8164526 TBMG_03716 Mycobacterium tuberculosis KZN 1435 endonuclease III nth YP_003033718.1 4101872 R 478434 CDS YP_003033719.1 253800718 8164527 4102717..4103094 1 NC_012943.1 hypothetical protein 4103094 8164527 TBMG_03717 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033719.1 4102717 D 478434 CDS YP_003033720.1 253800719 8164528 4103193..4103867 1 NC_012943.1 transcriptional regulator, crp/fnr-family 4103867 8164528 TBMG_03718 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, crp/fnr-family YP_003033720.1 4103193 D 478434 CDS YP_003033721.1 253800720 8164529 complement(4103973..4104767) 1 NC_012943.1 hydrolase 4104767 8164529 TBMG_03719 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003033721.1 4103973 R 478434 CDS YP_003033722.1 253800721 8164530 complement(4104774..4105229) 1 NC_012943.1 hypothetical protein 4105229 8164530 TBMG_03720 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033722.1 4104774 R 478434 CDS YP_003033723.1 253800722 8164531 complement(4105245..4105406) 1 NC_012943.1 hypothetical protein 4105406 8164531 TBMG_04118 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033723.1 4105245 R 478434 CDS YP_003033724.1 253800723 8164532 4105491..4106513 1 NC_012943.1 anion transporter ATPase 4106513 8164532 TBMG_03721 Mycobacterium tuberculosis KZN 1435 anion transporter ATPase YP_003033724.1 4105491 D 478434 CDS YP_003033725.1 253800724 8164533 4106510..4107670 1 NC_012943.1 anion transporter ATPase 4107670 8164533 TBMG_03722 Mycobacterium tuberculosis KZN 1435 anion transporter ATPase YP_003033725.1 4106510 D 478434 CDS YP_003033726.1 253800725 8164534 complement(4108084..4108440) 1 NC_012943.1 transcriptional regulator whib-like whiB4 4108440 8164534 TBMG_03723 Mycobacterium tuberculosis KZN 1435 transcriptional regulator whib-like whiB4 YP_003033726.1 4108084 R 478434 CDS YP_003033727.1 253800726 8164535 4108802..4111234 1 NC_012943.1 bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2 4111234 8164535 TBMG_03724 Mycobacterium tuberculosis KZN 1435 bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2 YP_003033727.1 4108802 D 478434 CDS YP_003033728.1 253800727 8164536 4111303..4112262 1 NC_012943.1 hypothetical protein 4112262 8164536 TBMG_03725 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033728.1 4111303 D 478434 CDS YP_003033729.1 253800728 8164537 4112259..4113365 1 NC_012943.1 lyase 4113365 8164537 TBMG_03726 Mycobacterium tuberculosis KZN 1435 lyase YP_003033729.1 4112259 D 478434 CDS YP_003033730.1 253800729 8164539 complement(4114181..4115611) 1 NC_012943.1 cytochrome P450 137 cyp137 4115611 8164539 TBMG_03727 Mycobacterium tuberculosis KZN 1435 cytochrome P450 137 cyp137 YP_003033730.1 4114181 R 478434 CDS YP_003033731.1 253800730 8164540 complement(4115637..4116086) 1 NC_012943.1 hypothetical protein 4116086 8164540 TBMG_03728 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033731.1 4115637 R 478434 CDS YP_003033732.1 253800731 8164541 complement(4116209..4116577) 1 NC_012943.1 anti-anti-sigma factor rsfB 4116577 8164541 TBMG_03729 Mycobacterium tuberculosis KZN 1435 anti-anti-sigma factor rsfB YP_003033732.1 4116209 R 478434 CDS YP_003033733.1 253800732 8164542 complement(4116779..4117243) 1 NC_012943.1 hypothetical protein 4117243 8164542 TBMG_03730 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033733.1 4116779 R 478434 CDS YP_003033734.1 253800733 8164544 4117243..4118598 1 NC_012943.1 hypothetical protein 4118598 8164544 TBMG_03731 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033734.1 4117243 D 478434 CDS YP_003033735.1 253800734 8164543 4118577..4119278 1 NC_012943.1 hypothetical protein 4119278 8164543 TBMG_03732 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033735.1 4118577 D 478434 CDS YP_003033736.1 253800735 8164545 4119275..4120405 1 NC_012943.1 hypothetical protein 4120405 8164545 TBMG_03733 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033736.1 4119275 D 478434 CDS YP_003033737.1 253800736 8164546 4120402..4121478 1 NC_012943.1 methanol dehydrogenase transcriptional regulator moxR2 4121478 8164546 TBMG_03734 Mycobacterium tuberculosis KZN 1435 methanol dehydrogenase transcriptional regulator moxR2 YP_003033737.1 4120402 D 478434 CDS YP_003033738.1 253800737 8164547 4121570..4122934 1 NC_012943.1 hypothetical protein 4122934 8164547 TBMG_03735 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033738.1 4121570 D 478434 CDS YP_003033739.1 253800738 8164548 complement(4123008..4124000) 1 NC_012943.1 hypothetical protein 4124000 8164548 TBMG_03736 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033739.1 4123008 R 478434 CDS YP_003033740.1 253800739 8164549 4124092..4125024 1 NC_012943.1 hypothetical protein 4125024 8164549 TBMG_03737 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033740.1 4124092 D 478434 CDS YP_003033741.1 253800740 8164550 complement(4125088..4126641) 1 NC_012943.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4126641 glpK 8164550 glpK Mycobacterium tuberculosis KZN 1435 glycerol kinase YP_003033741.1 4125088 R 478434 CDS YP_003033742.1 253800741 8164551 complement(4126691..4127128) 1 NC_012943.1 toxin 4127128 8164551 TBMG_03739 Mycobacterium tuberculosis KZN 1435 toxin YP_003033742.1 4126691 R 478434 CDS YP_003033743.1 253800742 8164552 complement(4127125..4127349) 1 NC_012943.1 antitoxin 4127349 8164552 TBMG_03740 Mycobacterium tuberculosis KZN 1435 antitoxin YP_003033743.1 4127125 R 478434 CDS YP_003033744.1 253800743 8164553 4127379..4128908 1 NC_012943.1 hypothetical protein 4128908 8164553 TBMG_03741 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033744.1 4127379 D 478434 CDS YP_003033745.1 253800744 8164554 4128930..4129631 1 NC_012943.1 hypothetical protein 4129631 8164554 TBMG_03742 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033745.1 4128930 D 478434 CDS YP_003033746.1 253800745 8164555 complement(4129634..4130821) 1 NC_012943.1 hypothetical protein 4130821 8164555 TBMG_03743 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033746.1 4129634 R 478434 CDS YP_003033747.1 253800746 8164556 complement(4130837..4131802) 1 NC_012943.1 methyltransferase 4131802 8164556 TBMG_03744 Mycobacterium tuberculosis KZN 1435 methyltransferase YP_003033747.1 4130837 R 478434 CDS YP_003033748.1 253800747 8164557 complement(4131799..4132500) 1 NC_012943.1 hypothetical protein 4132500 8164557 TBMG_03745 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033748.1 4131799 R 478434 CDS YP_003033749.1 253800748 8164558 complement(4132500..4133777) 1 NC_012943.1 hypothetical protein 4133777 8164558 TBMG_03746 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033749.1 4132500 R 478434 CDS YP_003033750.1 253800749 8164559 complement(4133774..4135072) 1 NC_012943.1 glutamate-cysteine ligase gshA 4135072 8164559 TBMG_03747 Mycobacterium tuberculosis KZN 1435 glutamate-cysteine ligase gshA YP_003033750.1 4133774 R 478434 CDS YP_003033751.1 253800750 8164560 complement(4135204..4135848) 1 NC_012943.1 hypothetical protein 4135848 8164560 TBMG_03748 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033751.1 4135204 R 478434 CDS YP_003033752.1 253800751 8164561 complement(4135977..4136366) 1 NC_012943.1 hypothetical protein 4136366 8164561 TBMG_03749 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033752.1 4135977 R 478434 CDS YP_003033753.1 253800752 8164562 complement(4136477..4136797) 1 NC_012943.1 hypothetical protein 4136797 8164562 TBMG_03750 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033753.1 4136477 R 478434 CDS YP_003033754.1 253800753 8164563 complement(4136916..4138022) 1 NC_012943.1 hypothetical protein 4138022 8164563 TBMG_03751 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033754.1 4136916 R 478434 CDS YP_003033755.1 253800754 8164564 complement(4138066..4139103) 1 NC_012943.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4139103 8164564 TBMG_03752 Mycobacterium tuberculosis KZN 1435 aspartate-semialdehyde dehydrogenase YP_003033755.1 4138066 R 478434 CDS YP_003033756.1 253800755 8164565 complement(4139104..4140369) 1 NC_012943.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 4140369 8164565 TBMG_03753 Mycobacterium tuberculosis KZN 1435 aspartate kinase YP_003033756.1 4139104 R 478434 CDS YP_003033757.1 253800756 8164566 4140626..4142560 1 NC_012943.1 2-isopropylmalate synthase 4142560 8164566 TBMG_03754 Mycobacterium tuberculosis KZN 1435 2-isopropylmalate synthase YP_003033757.1 4140626 D 478434 CDS YP_003033758.1 253800757 8164567 complement(4142626..4143615) 1 NC_012943.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 4143615 8164567 TBMG_03755 Mycobacterium tuberculosis KZN 1435 DNA polymerase III subunit epsilon YP_003033758.1 4142626 R 478434 CDS YP_003033759.1 253800758 8164568 4143926..4145167 1 NC_012943.1 ligase 4145167 8164568 TBMG_03756 Mycobacterium tuberculosis KZN 1435 ligase YP_003033759.1 4143926 D 478434 CDS YP_003033760.1 253800759 8164569 4145160..4145867 1 NC_012943.1 cobyric acid synthase cobQ2 4145867 8164569 TBMG_03757 Mycobacterium tuberculosis KZN 1435 cobyric acid synthase cobQ2 YP_003033760.1 4145160 D 478434 CDS YP_003033761.1 253800760 8164570 complement(4145876..4146766) 1 NC_012943.1 hypothetical protein 4146766 8164570 TBMG_03758 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033761.1 4145876 R 478434 CDS YP_003033762.1 253800761 8164571 complement(4146834..4147445) 1 NC_012943.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 4147445 recR 8164571 recR Mycobacterium tuberculosis KZN 1435 recombination protein RecR YP_003033762.1 4146834 R 478434 CDS YP_003033763.1 253800762 8164572 complement(4147457..4147858) 1 NC_012943.1 hypothetical protein 4147858 8164572 TBMG_03760 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033763.1 4147457 R 478434 CDS YP_003033764.1 253800763 8164573 4147993..4148718 1 NC_012943.1 hypothetical protein 4148718 8164573 TBMG_03761 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033764.1 4147993 D 478434 CDS YP_003033765.1 253800764 8164574 complement(4148760..4149203) 1 NC_012943.1 hypothetical protein 4149203 8164574 TBMG_03762 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033765.1 4148760 R 478434 CDS YP_003033766.1 253800765 8164575 4149251..4150663 1 NC_012943.1 hypothetical protein 4150663 8164575 TBMG_03763 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033766.1 4149251 D 478434 CDS YP_003033767.1 253800766 8164576 4150660..4151943 1 NC_012943.1 fatty-acid synthase 4151943 8164576 TBMG_03764 Mycobacterium tuberculosis KZN 1435 fatty-acid synthase YP_003033767.1 4150660 D 478434 CDS YP_003033768.1 253800767 8164577 complement(4151940..4153676) 1 NC_012943.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 4153676 8164577 TBMG_03765 Mycobacterium tuberculosis KZN 1435 DNA polymerase III subunits gamma and tau YP_003033768.1 4151940 R 478434 CDS YP_003033769.1 253800768 8164578 complement(4153766..4155073) 1 NC_012943.1 hypothetical protein 4155073 8164578 TBMG_03766 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033769.1 4153766 R 478434 CDS YP_003033770.1 253800769 8164580 4155481..4156245 1 NC_012943.1 hypothetical protein 4156245 8164580 TBMG_03767 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033770.1 4155481 D 478434 CDS YP_003033771.1 253800770 8164581 4156412..4156654 1 NC_012943.1 cutinase cut5a 4156654 8164581 TBMG_03768 Mycobacterium tuberculosis KZN 1435 cutinase cut5a YP_003033771.1 4156412 D 478434 CDS YP_003033772.1 253800771 8164582 4156491..4157114 1 NC_012943.1 cutinase cut5b 4157114 8164582 TBMG_03769 Mycobacterium tuberculosis KZN 1435 cutinase cut5b YP_003033772.1 4156491 D 478434 CDS YP_003033773.1 253800772 8164583 4157159..4158088 1 NC_012943.1 oxidoreductase 4158088 8164583 TBMG_03770 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033773.1 4157159 D 478434 CDS YP_003033774.1 253800773 8164584 4158366..4159559 1 NC_012943.1 dehydrogenase 4159559 8164584 TBMG_03771 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003033774.1 4158366 D 478434 CDS YP_003033775.1 253800774 8164585 4159900..4161708 1 NC_012943.1 oxidoreductase 4161708 8164585 TBMG_03772 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033775.1 4159900 D 478434 CDS YP_003033776.1 253800775 8164586 4161818..4165015 1 NC_012943.1 hypothetical protein 4165015 8164586 TBMG_03773 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033776.1 4161818 D 478434 CDS YP_003033777.1 253800776 8164587 4165194..4167560 1 NC_012943.1 transferase 4167560 8164587 TBMG_03774 Mycobacterium tuberculosis KZN 1435 transferase YP_003033777.1 4165194 D 478434 CDS YP_003033778.1 253800777 8164588 complement(4167625..4168665) 1 NC_012943.1 hypothetical protein 4168665 8164588 TBMG_03775 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033778.1 4167625 R 478434 CDS YP_003033779.1 253800778 8164589 4168703..4169779 1 NC_012943.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; ATP-dependent DNA ligase 4169779 ligC 8164589 ligC Mycobacterium tuberculosis KZN 1435 ATP-dependent DNA ligase YP_003033779.1 4168703 D 478434 CDS YP_003033780.1 253800779 8164590 4169879..4170937 1 NC_012943.1 hypothetical protein 4170937 8164590 TBMG_03777 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033780.1 4169879 D 478434 CDS YP_003033781.1 253800780 8164591 complement(4170982..4171458) 1 NC_012943.1 hypothetical protein 4171458 8164591 TBMG_03778 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033781.1 4170982 R 478434 CDS YP_003033782.1 253800781 8164592 complement(4171472..4172836) 1 NC_012943.1 hypothetical protein 4172836 8164592 TBMG_03779 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033782.1 4171472 R 478434 CDS YP_003033783.1 253800782 8164593 4173035..4173523 1 NC_012943.1 hypothetical protein 4173523 8164593 TBMG_03780 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033783.1 4173035 D 478434 CDS YP_003033784.1 253800783 8164594 4173580..4174641 1 NC_012943.1 AraC family transcriptional regulator 4174641 8164594 TBMG_03781 Mycobacterium tuberculosis KZN 1435 AraC family transcriptional regulator YP_003033784.1 4173580 D 478434 CDS YP_003033785.1 253800784 8164595 4174645..4176234 1 NC_012943.1 hypothetical protein 4176234 8164595 TBMG_03782 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033785.1 4174645 D 478434 CDS YP_003033786.1 253800785 8164596 complement(4176231..4177178) 1 NC_012943.1 PPE family protein 4177178 8164596 TBMG_03783 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033786.1 4176231 R 478434 CDS YP_003033787.1 253800786 8164597 complement(4177230..4177463) 1 NC_012943.1 PPE family protein 4177463 8164597 TBMG_03784 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033787.1 4177230 R 478434 CDS YP_003033788.1 253800787 8164598 complement(4177779..4179125) 1 NC_012943.1 hypothetical protein 4179125 8164598 TBMG_03785 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033788.1 4177779 R 478434 CDS YP_003033789.1 253800788 8164599 complement(4179125..4179799) 1 NC_012943.1 oxidoreductase 4179799 8164599 TBMG_03786 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033789.1 4179125 R 478434 CDS YP_003033790.1 253800789 8164600 complement(4179796..4180191) 1 NC_012943.1 oxidoreductase 4180191 8164600 TBMG_03787 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033790.1 4179796 R 478434 CDS YP_003033791.1 253800790 8164601 complement(4180337..4182319) 1 NC_012943.1 cation transporter P-type ATPase ctpJ 4182319 8164601 TBMG_03788 Mycobacterium tuberculosis KZN 1435 cation transporter P-type ATPase ctpJ YP_003033791.1 4180337 R 478434 CDS YP_003033792.1 253800791 8164602 4182341..4182748 1 NC_012943.1 transcriptional regulator, arsR-family 4182748 8164602 TBMG_03789 Mycobacterium tuberculosis KZN 1435 transcriptional regulator, arsR-family YP_003033792.1 4182341 D 478434 CDS YP_003033793.1 253800792 8164603 complement(4182832..4183044) 1 NC_012943.1 hypothetical protein 4183044 8164603 TBMG_03790 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033793.1 4182832 R 478434 CDS YP_003033794.1 253800793 8163706 complement(4183117..4183452) 1 NC_012943.1 PE family protein 4183452 8163706 TBMG_03791 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003033794.1 4183117 R 478434 CDS YP_003033795.1 253800794 8163811 4183670..4184053 1 NC_012943.1 hypothetical protein 4184053 8163811 TBMG_03792 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033795.1 4183670 D 478434 CDS YP_003033796.1 253800795 8163812 4184183..4184542 1 NC_012943.1 hypothetical protein 4184542 8163812 TBMG_03793 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033796.1 4184183 D 478434 CDS YP_003033797.1 253800796 8163813 complement(4184575..4185084) 1 NC_012943.1 hypothetical protein 4185084 8163813 TBMG_03794 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033797.1 4184575 R 478434 CDS YP_003033798.1 253800797 8163814 complement(4185152..4185544) 1 NC_012943.1 excisionase 4185544 8163814 TBMG_03795 Mycobacterium tuberculosis KZN 1435 excisionase YP_003033798.1 4185152 R 478434 CDS YP_003033799.1 253800798 8163815 4185820..4186035 1 NC_012943.1 integrase 4186035 8163815 TBMG_03796 Mycobacterium tuberculosis KZN 1435 integrase YP_003033799.1 4185820 D 478434 CDS YP_003033800.1 253800799 8163817 complement(4186193..4186651) 1 NC_012943.1 cytidine/deoxycytidylate deaminase 4186651 8163817 TBMG_03797 Mycobacterium tuberculosis KZN 1435 cytidine/deoxycytidylate deaminase YP_003033800.1 4186193 R 478434 CDS YP_003033801.1 253800800 8163818 complement(4186667..4187188) 1 NC_012943.1 hypothetical protein 4187188 8163818 TBMG_03798 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033801.1 4186667 R 478434 CDS YP_003033802.1 253800801 8163819 4187301..4188272 1 NC_012943.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 4188272 8163819 TBMG_03799 Mycobacterium tuberculosis KZN 1435 prephenate dehydrogenase YP_003033802.1 4187301 D 478434 CDS YP_003033803.1 253800802 8163820 complement(4188235..4188834) 1 NC_012943.1 hypothetical protein 4188834 8163820 TBMG_03800 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033803.1 4188235 R 478434 CDS YP_003033804.1 253800803 8163821 complement(4188840..4189559) 1 NC_012943.1 osmoprotectant proZ 4189559 8163821 TBMG_03801 Mycobacterium tuberculosis KZN 1435 osmoprotectant proZ YP_003033804.1 4188840 R 478434 CDS YP_003033805.1 253800804 8163822 complement(4189556..4190245) 1 NC_012943.1 osmoprotectant proW 4190245 8163822 TBMG_03802 Mycobacterium tuberculosis KZN 1435 osmoprotectant proW YP_003033805.1 4189556 R 478434 CDS YP_003033806.1 253800805 8163823 complement(4190233..4191363) 1 NC_012943.1 osmoprotectant proV 4191363 8163823 TBMG_03803 Mycobacterium tuberculosis KZN 1435 osmoprotectant proV YP_003033806.1 4190233 R 478434 CDS YP_003033807.1 253800806 8163824 complement(4191372..4192319) 1 NC_012943.1 osmoprotectant proX 4192319 8163824 TBMG_03804 Mycobacterium tuberculosis KZN 1435 osmoprotectant proX YP_003033807.1 4191372 R 478434 CDS YP_003033808.1 253800807 8163825 4192433..4192786 1 NC_012943.1 hypothetical protein 4192786 8163825 TBMG_03805 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033808.1 4192433 D 478434 CDS YP_003033809.1 253800808 8163826 complement(4192808..4193863) 1 NC_012943.1 acyl-CoA dehydrogenase 4193863 8163826 TBMG_03806 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033809.1 4192808 R 478434 CDS YP_003033810.1 253800809 8163827 complement(4193942..4195822) 1 NC_012943.1 hydrolase 4195822 8163827 TBMG_03807 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003033810.1 4193942 R 478434 CDS YP_003033811.1 253800810 8163828 4195993..4196472 1 NC_012943.1 19 kDa lipoprotein antigen precursor lpqH 4196472 8163828 TBMG_03808 Mycobacterium tuberculosis KZN 1435 19 kDa lipoprotein antigen precursor lpqH YP_003033811.1 4195993 D 478434 CDS YP_003033812.1 253800811 8163829 complement(4196528..4198048) 1 NC_012943.1 two component system sensor kinase 4198048 8163829 TBMG_03809 Mycobacterium tuberculosis KZN 1435 two component system sensor kinase YP_003033812.1 4196528 R 478434 CDS YP_003033813.1 253800812 8163830 complement(4198026..4198886) 1 NC_012943.1 two component system transcriptional regulator 4198886 8163830 TBMG_03810 Mycobacterium tuberculosis KZN 1435 two component system transcriptional regulator YP_003033813.1 4198026 R 478434 CDS YP_003033814.1 253800813 8163831 4199149..4199928 1 NC_012943.1 hypothetical protein 4199928 8163831 TBMG_03811 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033814.1 4199149 D 478434 CDS YP_003033815.1 253800814 8163832 complement(4199942..4200886) 1 NC_012943.1 hypothetical protein 4200886 8163832 TBMG_03812 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033815.1 4199942 R 478434 CDS YP_003033816.1 253800815 8163833 4201016..4201375 1 NC_012943.1 hypothetical protein 4201375 8163833 TBMG_03813 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033816.1 4201016 D 478434 CDS YP_003033817.1 253800816 8163834 4201561..4201833 1 NC_012943.1 hypothetical protein 4201833 8163834 TBMG_03814 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033817.1 4201561 D 478434 CDS YP_003033818.1 253800817 8163835 complement(4202146..4202721) 1 NC_012943.1 hypothetical protein 4202721 8163835 TBMG_03815 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033818.1 4202146 R 478434 CDS YP_003033819.1 253800818 8163836 complement(4202827..4203009) 1 NC_012943.1 transposase 4203009 8163836 TBMG_03816 Mycobacterium tuberculosis KZN 1435 transposase YP_003033819.1 4202827 R 478434 CDS YP_003033820.1 253800819 8163837 complement(4203024..4203215) 1 NC_012943.1 transposase 4203215 8163837 TBMG_03817 Mycobacterium tuberculosis KZN 1435 transposase YP_003033820.1 4203024 R 478434 CDS YP_003033821.1 253800820 8163838 complement(4203350..4203676) 1 NC_012943.1 hypothetical protein 4203676 8163838 TBMG_03818 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033821.1 4203350 R 478434 CDS YP_003033822.1 253800821 8163841 4204080..4205141 1 NC_012943.1 aminotransferase 4205141 8163841 TBMG_03819 Mycobacterium tuberculosis KZN 1435 aminotransferase YP_003033822.1 4204080 D 478434 CDS YP_003033823.1 253800822 8163842 complement(4205187..4205771) 1 NC_012943.1 hypothetical protein 4205771 8163842 TBMG_03820 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033823.1 4205187 R 478434 CDS YP_003033824.1 253800823 8163843 4205795..4206619 1 NC_012943.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4206619 8163843 TBMG_03821 Mycobacterium tuberculosis KZN 1435 enoyl-CoA hydratase YP_003033824.1 4205795 D 478434 CDS YP_003033825.1 253800824 8163844 4206631..4207878 1 NC_012943.1 lipase lipE 4207878 8163844 TBMG_03822 Mycobacterium tuberculosis KZN 1435 lipase lipE YP_003033825.1 4206631 D 478434 CDS YP_003033827.1 253800825 8163846 4209640..4210626 1 NC_012943.1 oxidoreductase 4210626 8163846 TBMG_03824 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033827.1 4209640 D 478434 CDS YP_003033828.1 253800826 8163847 complement(4210645..4211841) 1 NC_012943.1 aminotransferase 4211841 8163847 TBMG_03825 Mycobacterium tuberculosis KZN 1435 aminotransferase YP_003033828.1 4210645 R 478434 CDS YP_003033829.1 253800827 8163848 4211931..4213931 1 NC_012943.1 hypothetical protein 4213931 8163848 TBMG_03826 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033829.1 4211931 D 478434 CDS YP_003033830.1 253800828 8163849 4213935..4214471 1 NC_012943.1 hypothetical protein 4214471 8163849 TBMG_03827 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033830.1 4213935 D 478434 CDS YP_003033831.1 253800829 8163850 4214475..4215296 1 NC_012943.1 O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter rfbE 4215296 8163850 TBMG_03828 Mycobacterium tuberculosis KZN 1435 O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter rfbE YP_003033831.1 4214475 D 478434 CDS YP_003033832.1 253800830 8163851 4215293..4216207 1 NC_012943.1 L-rhamnosyltransferase 4216207 8163851 TBMG_03829 Mycobacterium tuberculosis KZN 1435 L-rhamnosyltransferase YP_003033832.1 4215293 D 478434 CDS YP_003033833.1 253800831 8163852 4216204..4217046 1 NC_012943.1 hypothetical protein 4217046 8163852 TBMG_03830 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033833.1 4216204 D 478434 CDS YP_003033834.1 253800832 8163853 4217202..4218182 1 NC_012943.1 dTDP-glucose 4,6-dehydratase 4218182 8163853 TBMG_03831 Mycobacterium tuberculosis KZN 1435 dTDP-glucose 4,6-dehydratase YP_003033834.1 4217202 D 478434 CDS YP_003033835.1 253800833 8163854 4218266..4219339 1 NC_012943.1 hypothetical protein 4219339 8163854 TBMG_03832 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033835.1 4218266 D 478434 CDS YP_003033836.1 253800834 8163855 complement(4219320..4220543) 1 NC_012943.1 hypothetical protein 4220543 8163855 TBMG_03833 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033836.1 4219320 R 478434 CDS YP_003033837.1 253800835 8163856 complement(4220556..4221482) 1 NC_012943.1 hypothetical protein 4221482 8163856 TBMG_03834 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033837.1 4220556 R 478434 CDS YP_003033838.1 253800836 8163857 4221726..4222211 1 NC_012943.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 4222211 8163857 TBMG_03835 Mycobacterium tuberculosis KZN 1435 nucleoside diphosphate kinase regulator YP_003033838.1 4221726 D 478434 CDS YP_003033839.1 253800837 8163858 4222257..4222685 1 NC_012943.1 hypothetical protein 4222685 8163858 TBMG_03836 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033839.1 4222257 D 478434 CDS YP_003033840.1 253800838 8163859 4222725..4224110 1 NC_012943.1 oxidoreductase 4224110 8163859 TBMG_03837 Mycobacterium tuberculosis KZN 1435 oxidoreductase YP_003033840.1 4222725 D 478434 CDS YP_003033841.1 253800839 8163860 4224111..4224875 1 NC_012943.1 short chain dehydrogenase 4224875 8163860 TBMG_03838 Mycobacterium tuberculosis KZN 1435 short chain dehydrogenase YP_003033841.1 4224111 D 478434 CDS YP_003033842.1 253800840 8163861 4224878..4226809 1 NC_012943.1 hypothetical protein 4226809 8163861 TBMG_03839 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033842.1 4224878 D 478434 CDS YP_003033843.1 253800841 8163862 4226809..4230093 1 NC_012943.1 membrane indolylacetylinositol arabinosyltransferase embC 4230093 8163862 TBMG_03840 Mycobacterium tuberculosis KZN 1435 membrane indolylacetylinositol arabinosyltransferase embC YP_003033843.1 4226809 D 478434 CDS YP_003033844.1 253800842 8163863 4230179..4233463 1 NC_012943.1 membrane indolylacetylinositol arabinosyltransferase embA 4233463 8163863 TBMG_03841 Mycobacterium tuberculosis KZN 1435 membrane indolylacetylinositol arabinosyltransferase embA YP_003033844.1 4230179 D 478434 CDS YP_003033845.1 253800843 8163864 4233460..4236756 1 NC_012943.1 membrane indolylacetylinositol arabinosyltransferase embB 4236756 8163864 TBMG_03842 Mycobacterium tuberculosis KZN 1435 membrane indolylacetylinositol arabinosyltransferase embB YP_003033845.1 4233460 D 478434 CDS YP_003033846.1 253800844 8163865 4236824..4237951 1 NC_012943.1 hypothetical protein 4237951 8163865 TBMG_03843 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033846.1 4236824 D 478434 CDS YP_003033847.1 253800845 8163866 4238031..4239812 1 NC_012943.1 acyl-CoA dehydrogenase 4239812 8163866 TBMG_03844 Mycobacterium tuberculosis KZN 1435 acyl-CoA dehydrogenase YP_003033847.1 4238031 D 478434 CDS YP_003033848.1 253800846 8163867 4239939..4241273 1 NC_012943.1 transposase 4241273 8163867 TBMG_03845 Mycobacterium tuberculosis KZN 1435 transposase YP_003033848.1 4239939 D 478434 CDS YP_003033849.1 253800847 8163868 complement(4241326..4242894) 1 NC_012943.1 propionyl-CoA carboxylase subunit beta 4242894 8163868 TBMG_03846 Mycobacterium tuberculosis KZN 1435 propionyl-CoA carboxylase subunit beta YP_003033849.1 4241326 R 478434 CDS YP_003033850.1 253800848 8163869 complement(4242891..4248092) 1 NC_012943.1 polyketide synthase 4248092 8163869 TBMG_03847 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003033850.1 4242891 R 478434 CDS YP_003033851.1 253800849 8163870 complement(4248099..4250012) 1 NC_012943.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 4250012 8163870 TBMG_03848 Mycobacterium tuberculosis KZN 1435 long-chain-fatty-acid--CoA ligase YP_003033851.1 4248099 R 478434 CDS YP_003033852.1 253800850 8163871 complement(4250301..4251311) 1 NC_012943.1 hypothetical protein 4251311 8163871 TBMG_03849 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033852.1 4250301 R 478434 CDS YP_003033853.1 253800851 8163872 complement(4251509..4252441) 1 NC_012943.1 secreted fibronectin-binding protein antigen protein fbpD 4252441 8163872 TBMG_03850 Mycobacterium tuberculosis KZN 1435 secreted fibronectin-binding protein antigen protein fbpD YP_003033853.1 4251509 R 478434 CDS YP_003033854.1 253800852 8163873 complement(4252588..4253604) 1 NC_012943.1 secreted fibronectin-binding protein antigen fbpA 4253604 8163873 TBMG_03851 Mycobacterium tuberculosis KZN 1435 secreted fibronectin-binding protein antigen fbpA YP_003033854.1 4252588 R 478434 CDS YP_003033855.1 253800853 8163874 complement(4253899..4255842) 1 NC_012943.1 hypothetical protein 4255842 8163874 TBMG_03852 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033855.1 4253899 R 478434 CDS YP_003033856.1 253800854 8163875 complement(4255871..4256779) 1 NC_012943.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase 4256779 8163875 TBMG_03853 Mycobacterium tuberculosis KZN 1435 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase YP_003033856.1 4255871 R 478434 CDS YP_003033857.1 253800855 8163876 complement(4256786..4257319) 1 NC_012943.1 hypothetical protein 4257319 8163876 TBMG_03854 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033857.1 4256786 R 478434 CDS YP_003033858.1 253800856 8163877 complement(4257312..4259225) 1 NC_012943.1 bifunctional UDP-galactofuranosyl transferase glfT 4259225 8163877 TBMG_03855 Mycobacterium tuberculosis KZN 1435 bifunctional UDP-galactofuranosyl transferase glfT YP_003033858.1 4257312 R 478434 CDS YP_003033859.1 253800857 8163878 complement(4259222..4260421) 1 NC_012943.1 UDP-galactopyranose mutase glf 4260421 8163878 TBMG_03856 Mycobacterium tuberculosis KZN 1435 UDP-galactopyranose mutase glf YP_003033859.1 4259222 R 478434 CDS YP_003033860.1 253800858 8163879 4260685..4261539 1 NC_012943.1 exported repetitive protein pirG 4261539 8163879 TBMG_03857 Mycobacterium tuberculosis KZN 1435 exported repetitive protein pirG YP_003033860.1 4260685 D 478434 CDS YP_003033861.1 253800859 8163880 4261744..4263363 1 NC_012943.1 hypothetical protein 4263363 8163880 TBMG_03858 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033861.1 4261744 D 478434 CDS YP_003033862.1 253800860 8163881 4263517..4265031 1 NC_012943.1 PE-PGRS family protein 4265031 8163881 TBMG_03859 Mycobacterium tuberculosis KZN 1435 PE-PGRS family protein YP_003033862.1 4263517 D 478434 CDS YP_003033863.1 253800861 8163882 complement(4265340..4266161) 1 NC_012943.1 hypothetical protein 4266161 8163882 TBMG_03860 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033863.1 4265340 R 478434 CDS YP_003033864.1 253800862 8163883 complement(4266176..4266961) 1 NC_012943.1 acyltransferase 4266961 8163883 TBMG_03861 Mycobacterium tuberculosis KZN 1435 acyltransferase YP_003033864.1 4266176 R 478434 CDS YP_003033865.1 253800863 8163884 complement(4266979..4267734) 1 NC_012943.1 acyltransferase 4267734 8163884 TBMG_03862 Mycobacterium tuberculosis KZN 1435 acyltransferase YP_003033865.1 4266979 R 478434 CDS YP_003033866.1 253800864 8163885 complement(4267738..4268517) 1 NC_012943.1 acyltransferase 4268517 8163885 TBMG_03863 Mycobacterium tuberculosis KZN 1435 acyltransferase YP_003033866.1 4267738 R 478434 CDS YP_003033867.1 253800865 8163886 4268593..4269348 1 NC_012943.1 phosphotransferase 4269348 8163886 TBMG_03864 Mycobacterium tuberculosis KZN 1435 phosphotransferase YP_003033867.1 4268593 D 478434 CDS YP_003033868.1 253800866 8163887 4269395..4270945 1 NC_012943.1 hypothetical protein 4270945 8163887 TBMG_03865 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033868.1 4269395 D 478434 CDS YP_003033869.1 253800867 8163888 4270942..4271277 1 NC_012943.1 hypothetical protein 4271277 8163888 TBMG_03866 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033869.1 4270942 D 478434 CDS YP_003033870.1 253800868 8163889 complement(4271365..4272771) 1 NC_012943.1 polyketide synthase 4272771 8163889 TBMG_03867 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003033870.1 4271365 R 478434 CDS YP_003033871.1 253800869 8163890 4272919..4273632 1 NC_012943.1 hypothetical protein 4273632 8163890 TBMG_03868 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033871.1 4272919 D 478434 CDS YP_003033872.1 253800870 8163891 4273667..4274881 1 NC_012943.1 hypothetical protein 4274881 8163891 TBMG_03869 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033872.1 4273667 D 478434 CDS YP_003033873.1 253800871 8164522 complement(4275206..4278475) 1 NC_012943.1 membrane transporter mmpL8 4278475 8164522 TBMG_03870 Mycobacterium tuberculosis KZN 1435 membrane transporter mmpL8 YP_003033873.1 4275206 R 478434 CDS YP_003033874.1 253800872 8162824 complement(4278585..4280120) 1 NC_012943.1 polyketide synthase 4280120 8162824 TBMG_03871 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003033874.1 4278585 R 478434 CDS YP_003033875.1 253800873 8162825 complement(4280171..4286551) 1 NC_012943.1 polyketide synthase 4286551 8162825 TBMG_03872 Mycobacterium tuberculosis KZN 1435 polyketide synthase YP_003033875.1 4280171 R 478434 CDS YP_003033876.1 253800874 8162826 4286758..4288512 1 NC_012943.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 4288512 8162826 TBMG_03873 Mycobacterium tuberculosis KZN 1435 acyl-CoA synthetase YP_003033876.1 4286758 D 478434 CDS YP_003033877.1 253800875 8162827 complement(4288509..4289735) 1 NC_012943.1 transposase 4289735 8162827 TBMG_03874 Mycobacterium tuberculosis KZN 1435 transposase YP_003033877.1 4288509 R 478434 CDS YP_003033878.1 253800876 8162828 complement(4289732..4290343) 1 NC_012943.1 resolvase 4290343 8162828 TBMG_03875 Mycobacterium tuberculosis KZN 1435 resolvase YP_003033878.1 4289732 R 478434 CDS YP_003033879.1 253800877 8162829 complement(4290344..4291969) 1 NC_012943.1 dehydrogenase 4291969 8162829 TBMG_03876 Mycobacterium tuberculosis KZN 1435 dehydrogenase YP_003033879.1 4290344 R 478434 CDS YP_003033880.1 253800878 8162830 complement(4292002..4292631) 1 NC_012943.1 TetR family transcriptional regulator 4292631 8162830 TBMG_03877 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033880.1 4292002 R 478434 CDS YP_003033881.1 253800879 8162831 4292703..4293185 1 NC_012943.1 hypothetical protein 4293185 8162831 TBMG_03878 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033881.1 4292703 D 478434 CDS YP_003033882.1 253800880 8162832 complement(4293182..4293757) 1 NC_012943.1 hypothetical protein 4293757 8162832 TBMG_04119 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033882.1 4293182 R 478434 CDS YP_003033883.1 253800881 8162833 4293813..4294604 1 NC_012943.1 AraC family transcriptional regulator 4294604 8162833 TBMG_03879 Mycobacterium tuberculosis KZN 1435 AraC family transcriptional regulator YP_003033883.1 4293813 D 478434 CDS YP_003033884.1 253800882 8162834 complement(4294601..4295860) 1 NC_012943.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 4295860 8162834 TBMG_03880 Mycobacterium tuberculosis KZN 1435 seryl-tRNA synthetase YP_003033884.1 4294601 R 478434 CDS YP_003033885.1 253800883 8162835 4295984..4297342 1 NC_012943.1 hypothetical protein 4297342 8162835 TBMG_03881 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033885.1 4295984 D 478434 CDS YP_003033886.1 253800884 8162836 4297347..4297760 1 NC_012943.1 hypothetical protein 4297760 8162836 TBMG_03882 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033886.1 4297347 D 478434 CDS YP_003033887.1 253800885 8162837 complement(4297955..4298653) 1 NC_012943.1 phosphoglycerate mutase 4298653 8162837 TBMG_03883 Mycobacterium tuberculosis KZN 1435 phosphoglycerate mutase YP_003033887.1 4297955 R 478434 CDS YP_003033888.1 253800886 8162838 complement(4298650..4299615) 1 NC_012943.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 4299615 8162838 TBMG_03884 Mycobacterium tuberculosis KZN 1435 prephenate dehydratase YP_003033888.1 4298650 R 478434 CDS YP_003033889.1 253800887 8162839 4299711..4300487 1 NC_012943.1 hypothetical protein 4300487 8162839 TBMG_03885 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033889.1 4299711 D 478434 CDS YP_003033890.1 253800888 8162840 4300513..4300926 1 NC_012943.1 transcriptional regulator 4300926 8162840 TBMG_03886 Mycobacterium tuberculosis KZN 1435 transcriptional regulator YP_003033890.1 4300513 D 478434 CDS YP_003033891.1 253800889 8162841 4301124..4301669 1 NC_012943.1 bacterioferritin bfrB 4301669 8162841 TBMG_03887 Mycobacterium tuberculosis KZN 1435 bacterioferritin bfrB YP_003033891.1 4301124 D 478434 CDS YP_003033892.1 253800890 8162842 complement(4301684..4302508) 1 NC_012943.1 glycerophosphoryl diester phosphodiesterase glpQ1 4302508 8162842 TBMG_03888 Mycobacterium tuberculosis KZN 1435 glycerophosphoryl diester phosphodiesterase glpQ1 YP_003033892.1 4301684 R 478434 CDS YP_003033893.1 253800891 8162843 complement(4302514..4303542) 1 NC_012943.1 hypothetical protein 4303542 8162843 TBMG_03889 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033893.1 4302514 R 478434 CDS YP_003033894.1 253800892 8162844 complement(4304631..4304843) 1 NC_012943.1 hypothetical protein 4304843 8162844 TBMG_03890 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033894.1 4304631 R 478434 CDS YP_003033895.1 253800893 8162845 complement(4305193..4305702) 1 NC_012943.1 hypothetical protein 4305702 8162845 TBMG_03891 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033895.1 4305193 R 478434 CDS YP_003033896.1 253800894 8162846 4305721..4306212 1 NC_012943.1 transposase 4306212 8162846 TBMG_03892 Mycobacterium tuberculosis KZN 1435 transposase YP_003033896.1 4305721 D 478434 CDS YP_003033897.1 253800895 8162847 4306227..4306586 1 NC_012943.1 hypothetical protein 4306586 8162847 TBMG_03893 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033897.1 4306227 D 478434 CDS YP_003033898.1 253800896 8162848 4306771..4306986 1 NC_012943.1 hypothetical protein 4306986 8162848 TBMG_03894 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033898.1 4306771 D 478434 CDS YP_003033899.1 253800897 8162849 4307650..4308273 1 NC_012943.1 superoxide dismutase [Fe] sodA 4308273 8162849 TBMG_03895 Mycobacterium tuberculosis KZN 1435 superoxide dismutase [Fe] sodA YP_003033899.1 4307650 D 478434 CDS YP_003033900.1 253800898 8162850 4308484..4309017 1 NC_012943.1 hypothetical protein 4309017 8162850 TBMG_03896 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033900.1 4308484 D 478434 CDS YP_003033901.1 253800899 8162851 4309272..4310180 1 NC_012943.1 hypothetical protein 4310180 8162851 TBMG_03897 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033901.1 4309272 D 478434 CDS YP_003033902.1 253800900 8162852 4310445..4310843 1 NC_012943.1 hypothetical protein 4310843 8162852 TBMG_03898 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033902.1 4310445 D 478434 CDS YP_003033903.1 253800901 8162853 4310961..4311617 1 NC_012943.1 hypothetical protein 4311617 8162853 TBMG_03899 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033903.1 4310961 D 478434 CDS YP_003033904.1 253800902 8162854 4311629..4311913 1 NC_012943.1 hypothetical protein 4311913 8162854 TBMG_03900 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033904.1 4311629 D 478434 CDS YP_003033905.1 253800903 8162855 4311999..4312424 1 NC_012943.1 histone-like protein hns 4312424 8162855 TBMG_03901 Mycobacterium tuberculosis KZN 1435 histone-like protein hns YP_003033905.1 4311999 D 478434 CDS YP_003033906.1 253800904 8162856 4312441..4312914 1 NC_012943.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4312914 8162856 TBMG_03902 Mycobacterium tuberculosis KZN 1435 ribonuclease activity regulator protein RraA YP_003033906.1 4312441 D 478434 CDS YP_003033907.1 253800905 8162857 complement(4312950..4314419) 1 NC_012943.1 monooxygenase ethA 4314419 8162857 TBMG_03903 Mycobacterium tuberculosis KZN 1435 monooxygenase ethA YP_003033907.1 4312950 R 478434 CDS YP_003033908.1 253800906 8162858 4314495..4315145 1 NC_012943.1 TetR family transcriptional regulator 4315145 8162858 TBMG_03904 Mycobacterium tuberculosis KZN 1435 TetR family transcriptional regulator YP_003033908.1 4314495 D 478434 CDS YP_003033909.1 253800907 8162859 complement(4315347..4316354) 1 NC_012943.1 hypothetical protein 4316354 8162859 TBMG_03905 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033909.1 4315347 R 478434 CDS YP_003033910.1 253800908 8162860 complement(4316363..4316560) 1 NC_012943.1 hypothetical protein 4316560 8162860 TBMG_03906 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033910.1 4316363 R 478434 CDS YP_003033911.1 253800909 8162861 complement(4316985..4318451) 1 NC_012943.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 4318451 gltD 8162861 gltD Mycobacterium tuberculosis KZN 1435 glutamate synthase subunit beta YP_003033911.1 4316985 R 478434 CDS YP_003033912.1 253800910 8162862 complement(4318444..4323027) 1 NC_012943.1 ferredoxin-dependent glutamate synthase [NADPH] large subunit gltB 4323027 8162862 TBMG_03908 Mycobacterium tuberculosis KZN 1435 ferredoxin-dependent glutamate synthase [NADPH] large subunit gltB YP_003033912.1 4318444 R 478434 CDS YP_003033913.1 253800911 8162863 4323724..4324896 1 NC_012943.1 hypothetical protein 4324896 8162863 TBMG_03909 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033913.1 4323724 D 478434 CDS YP_003033914.1 253800912 8162864 complement(4325118..4325468) 1 NC_012943.1 transcriptional regulator whiB-like whiB6 4325468 8162864 TBMG_03910 Mycobacterium tuberculosis KZN 1435 transcriptional regulator whiB-like whiB6 YP_003033914.1 4325118 R 478434 CDS YP_003033915.1 253800913 8162865 4325795..4326973 1 NC_012943.1 hypothetical protein 4326973 8162865 TBMG_03911 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033915.1 4325795 D 478434 CDS YP_003033916.1 253800914 8162866 4327216..4328424 1 NC_012943.1 hypothetical protein 4328424 8162866 TBMG_03912 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033916.1 4327216 D 478434 CDS YP_003033917.1 253800915 8162867 4328512..4328823 1 NC_012943.1 hypothetical protein 4328823 8162867 TBMG_03913 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033917.1 4328512 D 478434 CDS YP_003033918.1 253800916 8162868 4328826..4329677 1 NC_012943.1 hypothetical protein 4329677 8162868 TBMG_03914 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033918.1 4328826 D 478434 CDS YP_003033919.1 253800917 8162869 4329716..4330267 1 NC_012943.1 hypothetical protein 4330267 8162869 TBMG_03915 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033919.1 4329716 D 478434 CDS YP_003033920.1 253800918 8162870 4330260..4331981 1 NC_012943.1 hypothetical protein 4331981 8162870 TBMG_03916 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033920.1 4330260 D 478434 CDS YP_003033921.1 253800919 8162871 4331985..4333427 1 NC_012943.1 hypothetical protein 4333427 8162871 TBMG_03917 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033921.1 4331985 D 478434 CDS YP_003033922.1 253800920 8162872 4333427..4335670 1 NC_012943.1 hypothetical protein 4335670 8162872 TBMG_03918 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033922.1 4333427 D 478434 CDS YP_003033923.1 253800921 8162873 4335773..4337548 1 NC_012943.1 hypothetical protein 4337548 8162873 TBMG_03919 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033923.1 4335773 D 478434 CDS YP_003033924.1 253800922 8162874 4337691..4337987 1 NC_012943.1 hypothetical protein 4337987 8162874 TBMG_03920 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033924.1 4337691 D 478434 CDS YP_003033925.1 253800923 8162875 4338012..4339127 1 NC_012943.1 PPE family protein 4339127 8162875 TBMG_03921 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033925.1 4338012 D 478434 CDS YP_003033926.1 253800924 8162876 4339220..4339522 1 NC_012943.1 10 kDa culture filtrate antigen esxB 4339522 8162876 TBMG_03922 Mycobacterium tuberculosis KZN 1435 10 kDa culture filtrate antigen esxB YP_003033926.1 4339220 D 478434 CDS YP_003033927.1 253800925 8162877 4339555..4339842 1 NC_012943.1 hypothetical protein 4339842 8162877 TBMG_03923 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033927.1 4339555 D 478434 CDS YP_003033928.1 253800926 8162878 4339956..4341956 1 NC_012943.1 hypothetical protein 4341956 8162878 TBMG_03924 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033928.1 4339956 D 478434 CDS YP_003033929.1 253800927 8162879 4341953..4343488 1 NC_012943.1 hypothetical protein 4343488 8162879 TBMG_03925 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033929.1 4341953 D 478434 CDS YP_003033930.1 253800928 8162880 4343639..4344481 1 NC_012943.1 hypothetical protein 4344481 8162880 TBMG_03926 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033930.1 4343639 D 478434 CDS YP_003033931.1 253800929 8162881 complement(4344539..4346728) 1 NC_012943.1 hypothetical protein 4346728 8162881 TBMG_03927 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033931.1 4344539 R 478434 CDS YP_003033932.1 253800930 8162882 complement(4347145..4347492) 1 NC_012943.1 hypothetical protein 4347492 8162882 TBMG_03928 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033932.1 4347145 R 478434 CDS YP_003033933.1 253800931 8162883 complement(4347489..4348871) 1 NC_012943.1 hypothetical protein 4348871 8162883 TBMG_03929 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033933.1 4347489 R 478434 CDS YP_003033934.1 253800932 8162884 complement(4348978..4350366) 1 NC_012943.1 hypothetical protein 4350366 8162884 TBMG_03930 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033934.1 4348978 R 478434 CDS YP_003033935.1 253800933 8162885 complement(4350363..4351733) 1 NC_012943.1 membrane-anchored mycosin mycP1 4351733 8162885 TBMG_03931 Mycobacterium tuberculosis KZN 1435 membrane-anchored mycosin mycP1 YP_003033935.1 4350363 R 478434 CDS YP_003033936.1 253800934 8162886 complement(4351925..4353784) 1 NC_012943.1 cbxX/cfqX family protein 4353784 8162886 TBMG_03932 Mycobacterium tuberculosis KZN 1435 cbxX/cfqX family protein YP_003033936.1 4351925 R 478434 CDS YP_003033937.1 253800935 8162887 complement(4353854..4355467) 1 NC_012943.1 hypothetical protein 4355467 8162887 TBMG_03933 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033937.1 4353854 R 478434 CDS YP_003033938.1 253800936 8162888 complement(4355464..4357182) 1 NC_012943.1 hypothetical protein 4357182 8162888 TBMG_03934 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033938.1 4355464 R 478434 CDS YP_003033939.1 253800937 8162889 complement(4357101..4358630) 1 NC_012943.1 hypothetical protein 4358630 8162889 TBMG_03935 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033939.1 4357101 R 478434 CDS YP_003033940.1 253800938 8162890 complement(4358627..4359652) 1 NC_012943.1 hypothetical protein 4359652 8162890 TBMG_03936 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033940.1 4358627 R 478434 CDS YP_003033941.1 253800939 8162891 complement(4359746..4360576) 1 NC_012943.1 hypothetical protein 4360576 8162891 TBMG_03937 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033941.1 4359746 R 478434 CDS YP_003033942.1 253800940 8162892 complement(4360672..4360959) 1 NC_012943.1 esat-6 like protein esxC 4360959 8162892 TBMG_03938 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxC YP_003033942.1 4360672 R 478434 CDS YP_003033943.1 253800941 8162893 complement(4360995..4361318) 1 NC_012943.1 esat-6 like protein esxD 4361318 8162893 TBMG_03939 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxD YP_003033943.1 4360995 R 478434 CDS YP_003033944.1 253800942 8162894 complement(4361430..4362629) 1 NC_012943.1 PPE family protein 4362629 8162894 TBMG_03940 Mycobacterium tuberculosis KZN 1435 PPE family protein YP_003033944.1 4361430 R 478434 CDS YP_003033945.1 253800943 8162895 complement(4362708..4362941) 1 NC_012943.1 PE family protein 4362941 8162895 TBMG_03941 Mycobacterium tuberculosis KZN 1435 PE family protein YP_003033945.1 4362708 R 478434 CDS YP_003033946.1 253800944 8162896 complement(4363208..4367398) 1 NC_012943.1 hypothetical protein 4367398 8162896 TBMG_03942 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033946.1 4363208 R 478434 CDS YP_003033947.1 253800945 8162897 complement(4367399..4368886) 1 NC_012943.1 hypothetical protein 4368886 8162897 TBMG_03943 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033947.1 4367399 R 478434 CDS YP_003033948.1 253800946 8162898 complement(4368889..4369797) 1 NC_012943.1 hypothetical protein 4369797 8162898 TBMG_03944 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033948.1 4368889 R 478434 CDS YP_003033949.1 253800947 8162899 complement(4369947..4370591) 1 NC_012943.1 hypothetical protein 4370591 8162899 TBMG_03945 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033949.1 4369947 R 478434 CDS YP_003033950.1 253800948 8162900 complement(4370604..4370942) 1 NC_012943.1 hypothetical protein 4370942 8162900 TBMG_03946 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033950.1 4370604 R 478434 CDS YP_003033951.1 253800949 8162901 complement(4371098..4372330) 1 NC_012943.1 hypothetical protein 4372330 8162901 TBMG_03947 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033951.1 4371098 R 478434 CDS YP_003033952.1 253800950 8162902 complement(4372324..4373259) 1 NC_012943.1 hypothetical protein 4373259 8162902 TBMG_03948 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033952.1 4372324 R 478434 CDS YP_003033953.1 253800951 8162903 complement(4373316..4373765) 1 NC_012943.1 hypothetical protein 4373765 8162903 TBMG_03949 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033953.1 4373316 R 478434 CDS YP_003033954.1 253800952 8162904 complement(4374316..4374846) 1 NC_012943.1 hypothetical protein 4374846 8162904 TBMG_03950 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033954.1 4374316 R 478434 CDS YP_003033955.1 253800953 8161212 complement(4374843..4377383) 1 NC_012943.1 hypothetical protein 4377383 8161212 TBMG_03951 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033955.1 4374843 R 478434 CDS YP_003033956.1 253800954 8161213 complement(4377388..4377660) 1 NC_012943.1 esat-6 like protein esxE 4377660 8161213 TBMG_03952 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxE YP_003033956.1 4377388 R 478434 CDS YP_003033957.1 253800955 8161214 complement(4377671..4377982) 1 NC_012943.1 esat-6 like protein esxF 4377982 8161214 TBMG_03953 Mycobacterium tuberculosis KZN 1435 esat-6 like protein esxF YP_003033957.1 4377671 R 478434 CDS YP_003033958.1 253800956 8161215 complement(4378048..4378557) 1 NC_012943.1 hypothetical protein 4378557 8161215 TBMG_03954 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033958.1 4378048 R 478434 CDS YP_003033959.1 253800957 8161216 complement(4378582..4380024) 1 NC_012943.1 poly(A) polymerase 4380024 8161216 TBMG_03955 Mycobacterium tuberculosis KZN 1435 poly(A) polymerase YP_003033959.1 4378582 R 478434 CDS YP_003033960.1 253800958 8161217 4380400..4381146 1 NC_012943.1 hypothetical protein 4381146 8161217 TBMG_03956 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033960.1 4380400 D 478434 CDS YP_003033961.1 253800959 8161218 4381143..4383551 1 NC_012943.1 hypothetical protein 4383551 8161218 TBMG_03957 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033961.1 4381143 D 478434 CDS YP_003033962.1 253800960 8161219 4383548..4387102 1 NC_012943.1 hypothetical protein 4387102 8161219 TBMG_03958 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033962.1 4383548 D 478434 CDS YP_003033963.1 253800961 8161220 4387137..4387727 1 NC_012943.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase; RNA polymerase sigma factor SigM 4387727 8161220 TBMG_03959 Mycobacterium tuberculosis KZN 1435 RNA polymerase sigma factor SigM YP_003033963.1 4387137 D 478434 CDS YP_003033964.1 253800962 8161221 4387820..4388584 1 NC_012943.1 hypothetical protein 4388584 8161221 TBMG_03960 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033964.1 4387820 D 478434 CDS YP_003033965.1 253800963 8161222 4388678..4389685 1 NC_012943.1 thioredoxin reductase trxB2 4389685 8161222 TBMG_03961 Mycobacterium tuberculosis KZN 1435 thioredoxin reductase trxB2 YP_003033965.1 4388678 D 478434 CDS YP_003033966.1 253800964 8161223 4389682..4390032 1 NC_012943.1 thioredoxin trxC 4390032 8161223 TBMG_03962 Mycobacterium tuberculosis KZN 1435 thioredoxin trxC YP_003033966.1 4389682 D 478434 CDS YP_003033967.1 253800965 8161224 4390142..4391362 1 NC_012943.1 hydrolase 4391362 8161224 TBMG_03963 Mycobacterium tuberculosis KZN 1435 hydrolase YP_003033967.1 4390142 D 478434 CDS YP_003033968.1 253800966 8161225 complement(4391383..4392117) 1 NC_012943.1 hypothetical protein 4392117 8161225 TBMG_03964 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033968.1 4391383 R 478434 CDS YP_003033969.1 253800967 8161226 complement(4392407..4393441) 1 NC_012943.1 chromosome partitioning protein parB 4393441 8161226 TBMG_03965 Mycobacterium tuberculosis KZN 1435 chromosome partitioning protein parB YP_003033969.1 4392407 R 478434 CDS YP_003033970.1 253800968 8161227 complement(4393438..4394481) 1 NC_012943.1 chromosome partitioning protein parA 4394481 8161227 TBMG_03966 Mycobacterium tuberculosis KZN 1435 chromosome partitioning protein parA YP_003033970.1 4393438 R 478434 CDS YP_003033971.1 253800969 8161228 complement(4394478..4394891) 1 NC_012943.1 glucose-inhibited division protein B 4394891 8161228 TBMG_03967 Mycobacterium tuberculosis KZN 1435 glucose-inhibited division protein B YP_003033971.1 4394478 R 478434 CDS YP_003033972.1 253800970 8161229 complement(4395154..4395717) 1 NC_012943.1 hypothetical protein 4395717 8161229 TBMG_03968 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033972.1 4395154 R 478434 CDS YP_003033973.1 253800971 8161230 complement(4395789..4396889) 1 NC_012943.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4396889 8161230 TBMG_03969 Mycobacterium tuberculosis KZN 1435 inner membrane protein translocase component YidC YP_003033973.1 4395789 R 478434 CDS YP_003033974.1 253800972 8161231 complement(4396873..4397235) 1 NC_012943.1 hypothetical protein 4397235 8161231 TBMG_03970 Mycobacterium tuberculosis KZN 1435 hypothetical protein YP_003033974.1 4396873 R 478434 CDS YP_003033975.1 253800973 8161232 complement(4397232..4397609) 1 NC_012943.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4397609 rnpA 8161232 rnpA Mycobacterium tuberculosis KZN 1435 ribonuclease P YP_003033975.1 4397232 R 478434 CDS YP_003033976.1 253800974 8161233 complement(4397606..4397749) 1 NC_012943.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4397749 rpmH 8161233 rpmH Mycobacterium tuberculosis KZN 1435 50S ribosomal protein L34 YP_003033976.1 4397606 R 478434 CDS