-- dump date 20140619_131301 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_710182.1 24212701 1149344 234..1565 1 NC_004342.2 chromosomal replication initiation protein A 1565 dnaA 1149344 dnaA Leptospira interrogans serovar Lai str. 56601 chromosomal replication initiation protein A NP_710182.1 234 D 189518 CDS NP_710183.1 24212702 1149345 3221..4342 1 NC_004342.2 DNA polymerase III subunit beta 4342 dnaN 1149345 dnaN Leptospira interrogans serovar Lai str. 56601 DNA polymerase III subunit beta NP_710183.1 3221 D 189518 CDS NP_710184.1 24212703 1149346 5004..6101 1 NC_004342.2 recombination protein RecF 6101 recF 1149346 recF Leptospira interrogans serovar Lai str. 56601 recombination protein RecF NP_710184.1 5004 D 189518 CDS NP_710185.1 24212704 1149347 6098..6562 1 NC_004342.2 hypothetical protein 6562 1149347 LA_0004 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710185.1 6098 D 189518 CDS NP_710186.1 24212705 1149348 6626..8545 1 NC_004342.2 DNA gyrase subunit B 8545 gyrB 1149348 gyrB Leptospira interrogans serovar Lai str. 56601 DNA gyrase subunit B NP_710186.1 6626 D 189518 CDS NP_710187.1 24212706 1149349 8564..11068 1 NC_004342.2 DNA gyrase subunit A 11068 gyrA 1149349 gyrA Leptospira interrogans serovar Lai str. 56601 DNA gyrase subunit A NP_710187.1 8564 D 189518 CDS NP_710188.1 24212707 1149350 11073..12062 1 NC_004342.2 tRNA-dihydrouridine synthase 12062 1149350 LA_0007 Leptospira interrogans serovar Lai str. 56601 tRNA-dihydrouridine synthase NP_710188.1 11073 D 189518 CDS NP_710189.2 294827554 1149351 12213..12413 1 NC_004342.2 hypothetical protein 12413 1149351 LA_0008 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710189.2 12213 D 189518 CDS NP_710190.1 24212709 1149352 12655..13392 1 NC_004342.2 hypothetical protein 13392 1149352 LA_0009 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710190.1 12655 D 189518 CDS NP_710191.2 294827555 1149353 complement(13744..14646) 1 NC_004342.2 hypothetical protein 14646 1149353 LA_0010 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710191.2 13744 R 189518 CDS NP_710192.1 24212711 1149354 complement(15156..15716) 1 NC_004342.2 outer membrane lipoprotein LipL21 15716 lipL21 1149354 lipL21 Leptospira interrogans serovar Lai str. 56601 outer membrane lipoprotein LipL21 NP_710192.1 15156 R 189518 CDS NP_710193.2 294827556 1149355 15855..17402 1 NC_004342.2 hypothetical protein 17402 1149355 LA_0012 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710193.2 15855 D 189518 CDS NP_710194.1 24212713 1149356 17424..18317 1 NC_004342.2 transcriptional regulator 18317 1149356 LA_0013 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710194.1 17424 D 189518 CDS NP_710195.1 24212714 1149357 complement(18259..19347) 1 NC_004342.2 DNA-directed DNA polymerase subunit delta 19347 1149357 LA_0014 Leptospira interrogans serovar Lai str. 56601 DNA-directed DNA polymerase subunit delta NP_710195.1 18259 R 189518 CDS NP_710197.1 24212716 1149359 19919..20134 1 NC_004342.2 hypothetical protein 20134 1149359 LA_0016 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710197.1 19919 D 189518 CDS NP_710198.1 24212717 1149360 complement(20125..20688) 1 NC_004342.2 Maf-like protein 20688 maf 1149360 maf Leptospira interrogans serovar Lai str. 56601 Maf-like protein NP_710198.1 20125 R 189518 CDS NP_710199.2 294827557 1149361 20749..21645 1 NC_004342.2 hypothetical protein 21645 1149361 LA_0018 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710199.2 20749 D 189518 CDS NP_710200.1 24212719 1149362 21790..22293 1 NC_004342.2 hypothetical protein 22293 1149362 LA_0019 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710200.1 21790 D 189518 CDS NP_710201.1 24212720 1149363 22298..23041 1 NC_004342.2 short chain dehydrogenase 23041 fabG 1149363 fabG Leptospira interrogans serovar Lai str. 56601 short chain dehydrogenase NP_710201.1 22298 D 189518 CDS NP_710202.1 24212721 1149364 23057..23665 1 NC_004342.2 translation factor Sua5 23665 sua5 1149364 sua5 Leptospira interrogans serovar Lai str. 56601 translation factor Sua5 NP_710202.1 23057 D 189518 CDS NP_710203.1 24212722 1149365 24156..25838 1 NC_004342.2 hypothetical protein 25838 1149365 LA_0022 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710203.1 24156 D 189518 CDS NP_710205.2 294827558 1149367 complement(26668..27024) 1 NC_004342.2 glutaredoxin family protein 27024 arsC 1149367 arsC Leptospira interrogans serovar Lai str. 56601 glutaredoxin family protein NP_710205.2 26668 R 189518 CDS NP_710207.1 24212726 1149369 28064..29077 1 NC_004342.2 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 29077 fliG 1149369 fliG Leptospira interrogans serovar Lai str. 56601 flagellar motor switch protein G NP_710207.1 28064 D 189518 CDS NP_710208.1 24212727 1149370 29142..31418 1 NC_004342.2 guanylate cyclase 31418 1149370 LA_0027 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_710208.1 29142 D 189518 CDS NP_710210.1 24212729 1149372 32041..32598 1 NC_004342.2 hypothetical protein 32598 1149372 LA_0029 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710210.1 32041 D 189518 CDS NP_710211.2 294827559 1149373 32576..33772 1 NC_004342.2 hypothetical protein 33772 1149373 LA_0030 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710211.2 32576 D 189518 CDS NP_710212.1 24212731 1149374 33997..34701 1 NC_004342.2 hypothetical protein 34701 1149374 LA_0031 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710212.1 33997 D 189518 CDS NP_710213.1 24212732 1149375 34705..35064 1 NC_004342.2 hypothetical protein 35064 1149375 LA_0032 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710213.1 34705 D 189518 CDS NP_710214.1 24212733 1149376 complement(35061..35909) 1 NC_004342.2 inositol monophosphatase 35909 suhB 1149376 suhB Leptospira interrogans serovar Lai str. 56601 inositol monophosphatase NP_710214.1 35061 R 189518 CDS NP_710215.1 24212734 1149377 complement(35929..36840) 1 NC_004342.2 hypothetical protein 36840 1149377 LA_0034 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710215.1 35929 R 189518 CDS NP_710216.1 24212735 1149378 complement(37450..39426) 1 NC_004342.2 beta-galactosidase 39426 lacA 1149378 lacA Leptospira interrogans serovar Lai str. 56601 beta-galactosidase NP_710216.1 37450 R 189518 CDS NP_710218.1 24212737 1149380 39612..40469 1 NC_004342.2 HSP33-family chaperone 40469 1149380 LA_0036 Leptospira interrogans serovar Lai str. 56601 HSP33-family chaperone NP_710218.1 39612 D 189518 CDS NP_710219.1 24212738 1149381 40477..41049 1 NC_004342.2 ATPase 41049 1149381 LA_0038 Leptospira interrogans serovar Lai str. 56601 ATPase NP_710219.1 40477 D 189518 CDS NP_710220.2 294827560 1149382 41046..41726 1 NC_004342.2 metal-dependent molecular chaperone 41726 1149382 LA_0039 Leptospira interrogans serovar Lai str. 56601 metal-dependent molecular chaperone NP_710220.2 41046 D 189518 CDS NP_710221.1 24212740 1149383 41732..43978 1 NC_004342.2 ribonuclease R 43978 vacB 1149383 vacB Leptospira interrogans serovar Lai str. 56601 ribonuclease R NP_710221.1 41732 D 189518 CDS NP_710222.2 294827561 1149384 44150..44650 1 NC_004342.2 hypothetical protein 44650 1149384 LA_0041 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710222.2 44150 D 189518 CDS NP_710223.1 24212742 1149385 44654..46267 1 NC_004342.2 glucose-methanol-choline oxidoreductase 46267 1149385 LA_0042 Leptospira interrogans serovar Lai str. 56601 glucose-methanol-choline oxidoreductase NP_710223.1 44654 D 189518 CDS NP_710224.1 24212743 1149386 46409..47917 1 NC_004342.2 TPR-repeat-containing protein 47917 1149386 LA_0043 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710224.1 46409 D 189518 CDS NP_710226.1 24212745 1149388 complement(48128..48832) 1 NC_004342.2 3-dehydroquinate dehydratase 48832 aroD 1149388 aroD Leptospira interrogans serovar Lai str. 56601 3-dehydroquinate dehydratase NP_710226.1 48128 R 189518 CDS NP_710227.1 24212746 1149389 complement(48836..49804) 1 NC_004342.2 polysialic acid capsule expression protein 49804 gutQ 1149389 gutQ Leptospira interrogans serovar Lai str. 56601 polysialic acid capsule expression protein NP_710227.1 48836 R 189518 CDS NP_710228.1 24212747 1149390 complement(49788..50327) 1 NC_004342.2 transcription antiterminator 50327 1149390 LA_0047 Leptospira interrogans serovar Lai str. 56601 transcription antiterminator NP_710228.1 49788 R 189518 CDS NP_710229.1 24212748 1149391 complement(50311..50790) 1 NC_004342.2 hypothetical protein 50790 1149391 LA_0048 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710229.1 50311 R 189518 CDS NP_710230.1 24212749 1149392 51872..53569 1 NC_004342.2 methyl-accepting chemotaxis protein 53569 1149392 LA_0049 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_710230.1 51872 D 189518 CDS NP_710231.1 24212750 1149393 54175..55053 1 NC_004342.2 hypothetical protein 55053 1149393 LA_0050 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710231.1 54175 D 189518 CDS NP_710232.1 24212751 1149394 55050..55988 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 55988 wcaG 1149394 wcaG Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_710232.1 55050 D 189518 CDS NP_710233.1 24212752 1149395 56062..57231 1 NC_004342.2 NAD(P)(+) transhydrogenase subunit alpha 57231 pntA 1149395 pntA Leptospira interrogans serovar Lai str. 56601 NAD(P)(+) transhydrogenase subunit alpha NP_710233.1 56062 D 189518 CDS NP_710234.1 24212753 1149396 complement(57190..57726) 1 NC_004342.2 acid phosphatase 57726 1149396 LA_0053 Leptospira interrogans serovar Lai str. 56601 acid phosphatase NP_710234.1 57190 R 189518 CDS NP_710235.1 24212754 1149397 complement(57723..59042) 1 NC_004342.2 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 59042 hisS 1149397 hisS Leptospira interrogans serovar Lai str. 56601 histidyl-tRNA synthetase NP_710235.1 57723 R 189518 CDS NP_710236.1 24212755 1149398 complement(59049..60197) 1 NC_004342.2 hypothetical protein 60197 1149398 LA_0055 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710236.1 59049 R 189518 CDS NP_710237.1 24212756 1149399 complement(60207..62270) 1 NC_004342.2 OmpA family protein 62270 1149399 LA_0056 Leptospira interrogans serovar Lai str. 56601 OmpA family protein NP_710237.1 60207 R 189518 CDS NP_710238.1 24212757 1149400 62364..63206 1 NC_004342.2 dihydropteroate synthase 63206 folP 1149400 folP Leptospira interrogans serovar Lai str. 56601 dihydropteroate synthase NP_710238.1 62364 D 189518 CDS NP_710240.2 294827562 1149402 complement(63975..65063) 1 NC_004342.2 TPR-repeat-containing protein 65063 1149402 LA_0059 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710240.2 63975 R 189518 CDS NP_710241.1 24212760 1149403 complement(65283..66185) 1 NC_004342.2 TPR-repeat-containing protein 66185 1149403 LA_0060 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710241.1 65283 R 189518 CDS NP_710242.1 24212761 1149404 66235..67200 1 NC_004342.2 RlpA-like lipoprotein 67200 rlpA 1149404 rlpA Leptospira interrogans serovar Lai str. 56601 RlpA-like lipoprotein NP_710242.1 66235 D 189518 CDS NP_710243.1 24212762 1149405 complement(67903..68610) 1 NC_004342.2 serine acetyltransferase 68610 cysE 1149405 cysE Leptospira interrogans serovar Lai str. 56601 serine acetyltransferase NP_710243.1 67903 R 189518 CDS NP_710244.2 294827563 1149406 68863..69738 1 NC_004342.2 peptidase 69738 1149406 LA_0063 Leptospira interrogans serovar Lai str. 56601 peptidase NP_710244.2 68863 D 189518 CDS NP_710245.1 24212764 1149407 69702..71117 1 NC_004342.2 hypothetical protein 71117 1149407 LA_0064 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710245.1 69702 D 189518 CDS NP_710246.2 294827564 1149408 complement(71912..73123) 1 NC_004342.2 drug:Na+ antiporter of the multi antimicrobial extrusion family 73123 1149408 LA_0065 Leptospira interrogans serovar Lai str. 56601 drug:Na+ antiporter of the multi antimicrobial extrusion family NP_710246.2 71912 R 189518 CDS NP_710247.2 294827565 1149409 complement(73311..74543) 1 NC_004342.2 proton glutamate symport protein 74543 gltP 1149409 gltP Leptospira interrogans serovar Lai str. 56601 proton glutamate symport protein NP_710247.2 73311 R 189518 CDS NP_710248.1 24212767 1149410 74734..77919 1 NC_004342.2 hypothetical protein 77919 1149410 LA_0067 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710248.1 74734 D 189518 CDS NP_710249.1 24212768 1149411 77912..78802 1 NC_004342.2 hypothetical protein 78802 1149411 LA_0068 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710249.1 77912 D 189518 CDS NP_710251.2 294827566 1149413 79916..82879 1 NC_004342.2 hypothetical protein 82879 1149413 LA_0070 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710251.2 79916 D 189518 CDS NP_710252.2 294827567 1149414 complement(83593..84063) 1 NC_004342.2 hypothetical protein 84063 1149414 LA_0071 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710252.2 83593 R 189518 CDS NP_710253.1 24212772 1149415 complement(84139..84660) 1 NC_004342.2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 84660 dcd 1149415 dcd Leptospira interrogans serovar Lai str. 56601 deoxycytidine triphosphate deaminase NP_710253.1 84139 R 189518 CDS NP_710254.1 24212773 1149416 complement(84661..85443) 1 NC_004342.2 enoyl-CoA hydratase 85443 caiD 1149416 caiD Leptospira interrogans serovar Lai str. 56601 enoyl-CoA hydratase NP_710254.1 84661 R 189518 CDS NP_710255.2 294827568 1149417 85632..86270 1 NC_004342.2 hypothetical protein 86270 1149417 LA_0074 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710255.2 85632 D 189518 CDS NP_710256.2 294827569 1149418 87175..87384 1 NC_004342.2 hypothetical protein 87384 1149418 LA_0075 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710256.2 87175 D 189518 CDS NP_710257.2 294827570 1149419 complement(87472..87840) 1 NC_004342.2 dioxygenase superfamily protein 87840 1149419 LA_0076 Leptospira interrogans serovar Lai str. 56601 dioxygenase superfamily protein NP_710257.2 87472 R 189518 CDS NP_710258.1 24212777 1149420 complement(87950..89038) 1 NC_004342.2 hypothetical protein 89038 1149420 LA_0077 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710258.1 87950 R 189518 CDS NP_710259.2 294827571 1149421 complement(89035..90675) 1 NC_004342.2 hypothetical protein 90675 1149421 LA_0078 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710259.2 89035 R 189518 CDS NP_710262.1 24212781 1149424 90769..91518 1 NC_004342.2 hydrolase 91518 1149424 LA_0080 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_710262.1 90769 D 189518 CDS NP_710263.1 24212782 1149425 complement(91507..92358) 1 NC_004342.2 SAM-dependent methyltransferase 92358 1149425 LA_0082 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_710263.1 91507 R 189518 CDS NP_710264.1 24212783 1149426 92497..93342 1 NC_004342.2 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 93342 dapF 1149426 dapF Leptospira interrogans serovar Lai str. 56601 diaminopimelate epimerase NP_710264.1 92497 D 189518 CDS NP_710265.2 294827572 1149427 complement(93349..94053) 1 NC_004342.2 1-acylglycerol-3-phosphate O-acyltransferase 94053 1149427 LA_0084 Leptospira interrogans serovar Lai str. 56601 1-acylglycerol-3-phosphate O-acyltransferase NP_710265.2 93349 R 189518 CDS NP_710266.1 24212785 1149428 complement(94092..94376) 1 NC_004342.2 hypothetical protein 94376 1149428 LA_0085 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710266.1 94092 R 189518 CDS NP_710268.2 294827573 1149430 95001..96170 1 NC_004342.2 ISlin1 transposase 96170 1149430 LA_0087 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710268.2 95001 D 189518 CDS NP_710271.1 24212790 1149433 96862..97035 1 NC_004342.2 hypothetical protein 97035 1149433 LA_0089 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710271.1 96862 D 189518 CDS NP_710272.1 24212791 1149434 97163..97510 1 NC_004342.2 hypothetical protein 97510 1149434 LA_0091 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710272.1 97163 D 189518 CDS NP_710273.1 24212792 1149435 complement(97514..98089) 1 NC_004342.2 hypothetical protein 98089 1149435 LA_0092 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710273.1 97514 R 189518 CDS NP_710274.1 24212793 1149436 complement(98281..98814) 1 NC_004342.2 hypothetical protein 98814 1149436 LA_0093 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710274.1 98281 R 189518 CDS NP_710275.1 24212794 1149437 complement(99185..100006) 1 NC_004342.2 hypothetical protein 100006 1149437 LA_0094 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710275.1 99185 R 189518 CDS NP_710276.2 294827574 1149438 complement(100722..101132) 1 NC_004342.2 hypothetical protein 101132 1149438 LA_0095 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710276.2 100722 R 189518 CDS NP_710277.1 24212796 1149439 complement(101086..101532) 1 NC_004342.2 hypothetical protein 101532 1149439 LA_0097 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710277.1 101086 R 189518 CDS NP_710279.1 24212798 1149441 101861..103108 1 NC_004342.2 tRNA (uracil-5-)-methyltransferase 103108 trmA 1149441 trmA Leptospira interrogans serovar Lai str. 56601 tRNA (uracil-5-)-methyltransferase NP_710279.1 101861 D 189518 CDS NP_710280.2 294827575 1149442 103443..104051 1 NC_004342.2 hypothetical protein 104051 1149442 LA_0099 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710280.2 103443 D 189518 CDS NP_710281.2 294827576 1149443 104951..106225 1 NC_004342.2 hypothetical protein 106225 1149443 LA_0100 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710281.2 104951 D 189518 CDS NP_710282.1 24212801 1149444 106481..107170 1 NC_004342.2 hypothetical protein 107170 1149444 LA_0101 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710282.1 106481 D 189518 CDS NP_710283.1 24212802 1149445 107208..108755 1 NC_004342.2 hypothetical protein 108755 1149445 LA_0102 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710283.1 107208 D 189518 CDS NP_710284.1 24212803 1149446 108764..109807 1 NC_004342.2 hypothetical protein 109807 1149446 LA_0103 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710284.1 108764 D 189518 CDS NP_710285.1 24212804 1149447 109804..110661 1 NC_004342.2 metallo-beta-lactamase 110661 1149447 LA_0104 Leptospira interrogans serovar Lai str. 56601 metallo-beta-lactamase NP_710285.1 109804 D 189518 CDS NP_710286.1 24212805 1149448 complement(111132..112058) 1 NC_004342.2 hypothetical protein 112058 1149448 LA_0105 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710286.1 111132 R 189518 CDS NP_710287.2 294827577 1149449 complement(112177..114228) 1 NC_004342.2 long-chain-fatty-acid CoA ligase 114228 faa1 1149449 faa1 Leptospira interrogans serovar Lai str. 56601 long-chain-fatty-acid CoA ligase NP_710287.2 112177 R 189518 CDS NP_710288.1 24212807 1149450 complement(114407..114763) 1 NC_004342.2 hypothetical protein 114763 1149450 LA_0107 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710288.1 114407 R 189518 CDS NP_710289.1 24212808 1149451 complement(114736..115395) 1 NC_004342.2 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 115395 aat 1149451 aat Leptospira interrogans serovar Lai str. 56601 leucyl/phenylalanyl-tRNA--protein transferase NP_710289.1 114736 R 189518 CDS NP_710290.1 24212809 1149452 complement(115445..115993) 1 NC_004342.2 2'-5' RNA ligase 115993 ligT 1149452 ligT Leptospira interrogans serovar Lai str. 56601 2'-5' RNA ligase NP_710290.1 115445 R 189518 CDS NP_710291.1 24212810 1149453 complement(116041..117816) 1 NC_004342.2 para-aminobenzoate synthase component I 117816 1149453 LA_0110 Leptospira interrogans serovar Lai str. 56601 para-aminobenzoate synthase component I NP_710291.1 116041 R 189518 CDS NP_710292.2 294827578 1149454 117848..119992 1 NC_004342.2 two component system sensor histidine kinase\response regulator 119992 1149454 LA_0111 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase\response regulator NP_710292.2 117848 D 189518 CDS NP_710293.1 24212812 1149455 complement(120760..120963) 1 NC_004342.2 hypothetical protein 120963 1149455 LA_0112 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710293.1 120760 R 189518 CDS NP_710294.1 24212813 1149456 complement(121301..122803) 1 NC_004342.2 cystathionine gamma-synthase 122803 metC 1149456 metC Leptospira interrogans serovar Lai str. 56601 cystathionine gamma-synthase NP_710294.1 121301 R 189518 CDS NP_710295.1 24212814 1149457 complement(122863..123927) 1 NC_004342.2 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 123927 prfA 1149457 prfA Leptospira interrogans serovar Lai str. 56601 peptide chain release factor 1 NP_710295.1 122863 R 189518 CDS NP_710296.1 24212815 1149458 123968..124573 1 NC_004342.2 hypothetical protein 124573 1149458 LA_0115 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710296.1 123968 D 189518 CDS NP_710297.2 294827579 1149459 124674..125915 1 NC_004342.2 hypothetical protein 125915 1149459 LA_0116 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710297.2 124674 D 189518 CDS NP_710298.1 24212817 1149460 complement(126245..127267) 1 NC_004342.2 hypothetical protein 127267 1149460 LA_0117 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710298.1 126245 R 189518 CDS NP_710299.1 24212818 1149461 complement(127279..127713) 1 NC_004342.2 nudix hydrolase 127713 1149461 LA_0119 Leptospira interrogans serovar Lai str. 56601 nudix hydrolase NP_710299.1 127279 R 189518 CDS NP_710301.1 24212820 1149463 complement(128180..128848) 1 NC_004342.2 intramembrane serine protease 128848 glpG 1149463 glpG Leptospira interrogans serovar Lai str. 56601 intramembrane serine protease NP_710301.1 128180 R 189518 CDS NP_710302.1 24212821 1149464 complement(129171..129383) 1 NC_004342.2 hypothetical protein 129383 1149464 LA_0121 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710302.1 129171 R 189518 CDS NP_710305.1 24212824 1149467 130774..131394 1 NC_004342.2 imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase 131394 hisB 1149467 hisB Leptospira interrogans serovar Lai str. 56601 imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase NP_710305.1 130774 D 189518 CDS NP_710306.1 24212825 1149468 131391..132023 1 NC_004342.2 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 132023 hisH 1149468 hisH Leptospira interrogans serovar Lai str. 56601 imidazole glycerol phosphate synthase subunit HisH NP_710306.1 131391 D 189518 CDS NP_710307.1 24212826 1149469 132020..132745 1 NC_004342.2 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 132745 hisA 1149469 hisA Leptospira interrogans serovar Lai str. 56601 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase NP_710307.1 132020 D 189518 CDS NP_710308.1 24212827 1149470 132836..134050 1 NC_004342.2 hypothetical protein 134050 1149470 LA_0127 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710308.1 132836 D 189518 CDS NP_710309.2 294827580 1149471 134209..134598 1 NC_004342.2 hypothetical protein 134598 1149471 LA_0128 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710309.2 134209 D 189518 CDS NP_710310.2 294827581 1149472 134997..136820 1 NC_004342.2 hypothetical protein 136820 1149472 LA_0129 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710310.2 134997 D 189518 CDS NP_710311.1 24212830 1149473 complement(137831..138652) 1 NC_004342.2 phosphomethylpyrimidine kinase protein 138652 thiD 1149473 thiD Leptospira interrogans serovar Lai str. 56601 phosphomethylpyrimidine kinase protein NP_710311.1 137831 R 189518 CDS NP_710312.1 24212831 1149474 complement(139659..140072) 1 NC_004342.2 methylated-DNA--protein-cysteine methyltransferase 140072 1149474 LA_0131 Leptospira interrogans serovar Lai str. 56601 methylated-DNA--protein-cysteine methyltransferase NP_710312.1 139659 R 189518 CDS NP_710313.1 24212832 1149475 complement(140097..140249) 1 NC_004342.2 hypothetical protein 140249 1149475 LA_0132 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710313.1 140097 R 189518 CDS NP_710314.2 294827582 1149476 complement(140801..142519) 1 NC_004342.2 two component system sensor histidine kinase 142519 1149476 LA_0133 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase NP_710314.2 140801 R 189518 CDS NP_710315.1 24212834 1149477 142648..143604 1 NC_004342.2 ribosome-associated GTPase 143604 1149477 LA_0134 Leptospira interrogans serovar Lai str. 56601 ribosome-associated GTPase NP_710315.1 142648 D 189518 CDS NP_710316.1 24212835 1149478 143601..144902 1 NC_004342.2 hypothetical protein 144902 1149478 LA_0135 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710316.1 143601 D 189518 CDS NP_710317.2 294827583 1149479 145035..145964 1 NC_004342.2 hypothetical protein 145964 1149479 LA_0136 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710317.2 145035 D 189518 CDS NP_710318.2 294827584 1149480 146117..147730 1 NC_004342.2 hypothetical protein 147730 1149480 LA_0137 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710318.2 146117 D 189518 CDS NP_710319.1 24212838 1149481 147727..151320 1 NC_004342.2 TPR-repeat-containing protein 151320 1149481 LA_0138 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710319.1 147727 D 189518 CDS NP_710321.1 24212840 1149483 complement(152048..152701) 1 NC_004342.2 methyltransferase 152701 1149483 LA_0140 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_710321.1 152048 R 189518 CDS NP_710322.1 24212841 1149484 152751..153689 1 NC_004342.2 metal-dependent hydrolase of the beta-lactamase superfamily I 153689 1149484 LA_0141 Leptospira interrogans serovar Lai str. 56601 metal-dependent hydrolase of the beta-lactamase superfamily I NP_710322.1 152751 D 189518 CDS NP_710323.2 294827585 1149485 153952..154164 1 NC_004342.2 hypothetical protein 154164 1149485 LA_0142 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710323.2 153952 D 189518 CDS NP_710324.1 24212843 1149486 154281..154949 1 NC_004342.2 hypothetical protein 154949 1149486 LA_0143 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710324.1 154281 D 189518 CDS NP_710325.1 24212844 1149487 complement(155173..155826) 1 NC_004342.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 155826 engB 1149487 engB Leptospira interrogans serovar Lai str. 56601 ribosome biogenesis GTP-binding protein YsxC NP_710325.1 155173 R 189518 CDS NP_710326.1 24212845 1149488 complement(155823..157124) 1 NC_004342.2 cell cycle protein 157124 1149488 LA_0145 Leptospira interrogans serovar Lai str. 56601 cell cycle protein NP_710326.1 155823 R 189518 CDS NP_710327.1 24212846 1149489 157912..160011 1 NC_004342.2 transcriptional regulator 160011 fhlA 1149489 fhlA Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710327.1 157912 D 189518 CDS NP_710328.1 24212847 1149490 complement(160469..160705) 1 NC_004342.2 hypothetical protein 160705 1149490 LA_0148 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710328.1 160469 R 189518 CDS NP_710329.1 24212848 1149491 160685..161911 1 NC_004342.2 hypothetical protein 161911 1149491 LA_0147 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710329.1 160685 D 189518 CDS NP_710330.1 24212849 1149492 complement(161900..162298) 1 NC_004342.2 SET domain-containing protein 162298 1149492 LA_0149 Leptospira interrogans serovar Lai str. 56601 SET domain-containing protein NP_710330.1 161900 R 189518 CDS NP_710331.1 24212850 1149493 complement(162352..164172) 1 NC_004342.2 multidrug ABC transporter ATPase/permease 164172 mdlB 1149493 mdlB Leptospira interrogans serovar Lai str. 56601 multidrug ABC transporter ATPase/permease NP_710331.1 162352 R 189518 CDS NP_710332.1 24212851 1149494 164345..164959 1 NC_004342.2 hypothetical protein 164959 1149494 LA_0151 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710332.1 164345 D 189518 CDS NP_710334.1 24212853 1149496 165126..166595 1 NC_004342.2 hypothetical protein 166595 1149496 LA_0153 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710334.1 165126 D 189518 CDS NP_710337.2 294827586 1149499 167908..169404 1 NC_004342.2 hypothetical protein 169404 1149499 LA_0156 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710337.2 167908 D 189518 CDS NP_710338.1 24212857 1149500 169466..170608 1 NC_004342.2 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 170608 aroC 1149500 aroC Leptospira interrogans serovar Lai str. 56601 chorismate synthase NP_710338.1 169466 D 189518 CDS NP_710341.1 24212860 1149503 171412..172860 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain G 172860 nuoG 1149503 nuoG Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain G NP_710341.1 171412 D 189518 CDS NP_710342.1 24212861 1149504 172847..173374 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain I 173374 nuoI 1149504 nuoI Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain I NP_710342.1 172847 D 189518 CDS NP_710344.1 24212863 1149506 complement(173797..174045) 1 NC_004342.2 hypothetical protein 174045 1149506 LA_0163 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710344.1 173797 R 189518 CDS NP_710346.1 24212865 1149508 174390..174914 1 NC_004342.2 RNA polymerase ECF-type sigma factor 174914 rpoE 1149508 rpoE Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_710346.1 174390 D 189518 CDS NP_710347.1 24212866 1149509 174924..176297 1 NC_004342.2 hypothetical protein 176297 1149509 LA_0166 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710347.1 174924 D 189518 CDS NP_710350.2 294827587 1149512 177684..178334 1 NC_004342.2 polyketide biosynthesis dithiol-disulfide isomerase 178334 frnE 1149512 frnE Leptospira interrogans serovar Lai str. 56601 polyketide biosynthesis dithiol-disulfide isomerase NP_710350.2 177684 D 189518 CDS NP_710352.2 161484957 1149514 179525..180778 1 NC_004342.2 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 180778 avtA 1149514 avtA Leptospira interrogans serovar Lai str. 56601 valine--pyruvate transaminase NP_710352.2 179525 D 189518 CDS NP_710353.2 294827588 1149515 180866..183208 1 NC_004342.2 hypothetical protein 183208 1149515 LA_0172 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710353.2 180866 D 189518 CDS NP_710356.1 24212875 1149518 184417..184578 1 NC_004342.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 184578 rpmH 1149518 rpmH Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L34 NP_710356.1 184417 D 189518 CDS NP_710358.1 24212877 1149520 184905..185129 1 NC_004342.2 hypothetical protein 185129 1149520 LA_0177 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710358.1 184905 D 189518 CDS NP_710359.1 24212878 1149521 185139..187022 1 NC_004342.2 preprotein translocase subunit YidC 187022 yidC 1149521 yidC Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit YidC NP_710359.1 185139 D 189518 CDS NP_710360.1 24212879 1149522 187054..187764 1 NC_004342.2 Jag-like RNA-binding protein 187764 jag 1149522 jag Leptospira interrogans serovar Lai str. 56601 Jag-like RNA-binding protein NP_710360.1 187054 D 189518 CDS NP_710361.1 24212880 1149523 187757..189127 1 NC_004342.2 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 189127 trmE 1149523 trmE Leptospira interrogans serovar Lai str. 56601 tRNA modification GTPase TrmE NP_710361.1 187757 D 189518 CDS NP_710362.2 294827589 1149524 189175..190437 1 NC_004342.2 malic enzyme 190437 sfcA 1149524 sfcA Leptospira interrogans serovar Lai str. 56601 malic enzyme NP_710362.2 189175 D 189518 CDS NP_710365.1 24212884 1149527 191138..193216 1 NC_004342.2 hypothetical protein 193216 1149527 LA_0184 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710365.1 191138 D 189518 CDS NP_710366.1 24212885 1149528 193303..194697 1 NC_004342.2 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 194697 fumC 1149528 fumC Leptospira interrogans serovar Lai str. 56601 fumarate hydratase NP_710366.1 193303 D 189518 CDS NP_710367.2 294827590 1149529 complement(195061..195207) 1 NC_004342.2 hypothetical protein 195207 1149529 LA_0186 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710367.2 195061 R 189518 CDS NP_710368.1 24212887 1149530 complement(195204..195644) 1 NC_004342.2 hypothetical protein 195644 1149530 LA_0187 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710368.1 195204 R 189518 CDS NP_710369.1 24212888 1149531 complement(195667..195864) 1 NC_004342.2 hypothetical protein 195864 1149531 LA_0188 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710369.1 195667 R 189518 CDS NP_710370.1 24212889 1149532 complement(195924..196520) 1 NC_004342.2 Mu-like prophage host-nuclease inhibitor protein Gam 196520 1149532 LA_0189 Leptospira interrogans serovar Lai str. 56601 Mu-like prophage host-nuclease inhibitor protein Gam NP_710370.1 195924 R 189518 CDS NP_710372.1 24212891 1149534 complement(196707..197174) 1 NC_004342.2 hypothetical protein 197174 1149534 LA_0191 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710372.1 196707 R 189518 CDS NP_710373.1 24212892 1149535 complement(197181..197360) 1 NC_004342.2 hypothetical protein 197360 1149535 LA_0192 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710373.1 197181 R 189518 CDS NP_710374.1 24212893 1149536 complement(197391..197696) 1 NC_004342.2 hypothetical protein 197696 1149536 LA_0193 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710374.1 197391 R 189518 CDS NP_710375.2 294827591 1149537 complement(197696..197935) 1 NC_004342.2 hypothetical protein 197935 1149537 LA_0194 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710375.2 197696 R 189518 CDS NP_710376.2 294827592 1149538 198103..198501 1 NC_004342.2 transcriptional regulator 198501 1149538 LA_0195 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710376.2 198103 D 189518 CDS NP_710379.1 24212898 1149541 199254..199556 1 NC_004342.2 hypothetical protein 199556 1149541 LA_0198 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710379.1 199254 D 189518 CDS NP_710382.1 24212901 1149544 199971..200297 1 NC_004342.2 hypothetical protein 200297 1149544 LA_0201 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710382.1 199971 D 189518 CDS NP_710383.2 294827593 1149545 200351..200920 1 NC_004342.2 hypothetical protein 200920 1149545 LA_0202 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710383.2 200351 D 189518 CDS NP_710384.1 24212903 1149546 202045..202659 1 NC_004342.2 hypothetical protein 202659 1149546 LA_0203 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710384.1 202045 D 189518 CDS NP_710385.1 24212904 1149547 202656..202892 1 NC_004342.2 hypothetical protein 202892 1149547 LA_0204 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710385.1 202656 D 189518 CDS NP_710386.1 24212905 1149548 202969..204456 1 NC_004342.2 hypothetical protein 204456 1149548 LA_0205 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710386.1 202969 D 189518 CDS NP_710387.1 24212906 1149549 204466..204900 1 NC_004342.2 hypothetical protein 204900 1149549 LA_0206 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710387.1 204466 D 189518 CDS NP_710388.1 24212907 1149550 204946..205356 1 NC_004342.2 hypothetical protein 205356 1149550 LA_0207 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710388.1 204946 D 189518 CDS NP_710390.2 294827594 1149552 205585..207741 1 NC_004342.2 phage-like protein 207741 1149552 LA_0209 Leptospira interrogans serovar Lai str. 56601 phage-like protein NP_710390.2 205585 D 189518 CDS NP_710391.1 24212910 1149553 207738..208283 1 NC_004342.2 hypothetical protein 208283 1149553 LA_0210 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710391.1 207738 D 189518 CDS NP_710392.1 24212911 1149554 208280..208651 1 NC_004342.2 hypothetical protein 208651 1149554 LA_0211 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710392.1 208280 D 189518 CDS NP_710393.1 24212912 1149555 208651..209682 1 NC_004342.2 hypothetical protein 209682 1149555 LA_0212 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710393.1 208651 D 189518 CDS NP_710394.1 24212913 1149556 209694..210266 1 NC_004342.2 hypothetical protein 210266 1149556 LA_0213 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710394.1 209694 D 189518 CDS NP_710395.1 24212914 1149557 210266..210628 1 NC_004342.2 hypothetical protein 210628 1149557 LA_0214 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710395.1 210266 D 189518 CDS NP_710396.1 24212915 1149558 210852..211982 1 NC_004342.2 hypothetical protein 211982 1149558 LA_0215 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710396.1 210852 D 189518 CDS NP_710397.2 294827595 1149559 211975..212640 1 NC_004342.2 hypothetical protein 212640 1149559 LA_0216 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710397.2 211975 D 189518 CDS NP_710398.1 24212917 1149560 212706..213428 1 NC_004342.2 hypothetical protein 213428 1149560 LA_0217 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710398.1 212706 D 189518 CDS NP_710399.1 24212918 1149561 213421..214953 1 NC_004342.2 hypothetical protein 214953 1149561 LA_0218 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710399.1 213421 D 189518 CDS NP_710400.1 24212919 1149562 215823..217379 1 NC_004342.2 hypothetical protein 217379 1149562 LA_0219 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710400.1 215823 D 189518 CDS NP_710402.1 24212921 1149564 218431..220110 1 NC_004342.2 cytoplasmic membrane protein 220110 1149564 LA_0221 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_710402.1 218431 D 189518 CDS NP_710403.1 24212922 1149565 complement(220446..221033) 1 NC_004342.2 OmpA family lipoprotein 221033 1149565 LA_0222 Leptospira interrogans serovar Lai str. 56601 OmpA family lipoprotein NP_710403.1 220446 R 189518 CDS NP_710404.1 24212923 1149566 221168..222106 1 NC_004342.2 ribosomal large subunit pseudouridine synthase 222106 rluA 1149566 rluA Leptospira interrogans serovar Lai str. 56601 ribosomal large subunit pseudouridine synthase NP_710404.1 221168 D 189518 CDS NP_710405.1 24212924 1149567 complement(222075..222917) 1 NC_004342.2 amidohydrolase 222917 1149567 LA_0224 Leptospira interrogans serovar Lai str. 56601 amidohydrolase NP_710405.1 222075 R 189518 CDS NP_710406.1 24212925 1149568 complement(223000..223752) 1 NC_004342.2 short-chain dehydrogenase 223752 dltE 1149568 dltE Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_710406.1 223000 R 189518 CDS NP_710407.2 294827596 1149569 complement(223749..224738) 1 NC_004342.2 DNA repair photolyase 224738 1149569 LA_0226 Leptospira interrogans serovar Lai str. 56601 DNA repair photolyase NP_710407.2 223749 R 189518 CDS NP_710408.1 24212927 1149570 complement(224758..225633) 1 NC_004342.2 hypothetical protein 225633 1149570 LA_0227 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710408.1 224758 R 189518 CDS NP_710409.2 294827597 1149571 225710..226024 1 NC_004342.2 hypothetical protein 226024 1149571 LA_0228 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710409.2 225710 D 189518 CDS NP_710410.1 24212929 1149572 226021..226836 1 NC_004342.2 inositol monophosphatase 226836 suhB 1149572 suhB Leptospira interrogans serovar Lai str. 56601 inositol monophosphatase NP_710410.1 226021 D 189518 CDS NP_710412.1 24212931 1149574 complement(227144..228478) 1 NC_004342.2 glycosyltransferase 228478 1149574 LA_0231 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_710412.1 227144 R 189518 CDS NP_710413.1 24212932 1149575 complement(228462..229511) 1 NC_004342.2 glycosyltransferase 229511 1149575 LA_0232 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_710413.1 228462 R 189518 CDS NP_710414.1 24212933 1149576 complement(229508..230566) 1 NC_004342.2 glycosyltransferase 230566 1149576 LA_0233 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_710414.1 229508 R 189518 CDS NP_710415.2 294827598 1149577 complement(230563..231567) 1 NC_004342.2 hypothetical protein 231567 1149577 LA_0234 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710415.2 230563 R 189518 CDS NP_710416.1 24212935 1149578 231653..232618 1 NC_004342.2 dTDP-D-glucose 4,6-dehydratase 232618 rfbB 1149578 rfbB Leptospira interrogans serovar Lai str. 56601 dTDP-D-glucose 4,6-dehydratase NP_710416.1 231653 D 189518 CDS NP_710418.1 24212937 1149580 complement(233785..234654) 1 NC_004342.2 cytochrome C oxidase assembly protein 234654 cyoE 1149580 cyoE Leptospira interrogans serovar Lai str. 56601 cytochrome C oxidase assembly protein NP_710418.1 233785 R 189518 CDS NP_710419.1 24212938 1149581 complement(234670..235617) 1 NC_004342.2 cytochrome oxidase assembly protein 235617 ctaA 1149581 ctaA Leptospira interrogans serovar Lai str. 56601 cytochrome oxidase assembly protein NP_710419.1 234670 R 189518 CDS NP_710421.2 294827599 1149583 235867..236019 1 NC_004342.2 hypothetical protein 236019 1149583 LA_0240 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710421.2 235867 D 189518 CDS NP_710422.1 24212941 1149584 236045..236884 1 NC_004342.2 SCO1/SenC/PrrC family protein 236884 1149584 LA_0241 Leptospira interrogans serovar Lai str. 56601 SCO1/SenC/PrrC family protein NP_710422.1 236045 D 189518 CDS NP_710423.2 294827600 1149585 236931..237896 1 NC_004342.2 cytochrome c oxidase subunit II 237896 cyoA 1149585 cyoA Leptospira interrogans serovar Lai str. 56601 cytochrome c oxidase subunit II NP_710423.2 236931 D 189518 CDS NP_710424.1 24212943 1149586 237907..239511 1 NC_004342.2 cytochrome c oxidase polypeptide I 239511 cyoB 1149586 cyoB Leptospira interrogans serovar Lai str. 56601 cytochrome c oxidase polypeptide I NP_710424.1 237907 D 189518 CDS NP_710425.1 24212944 1149587 239498..240142 1 NC_004342.2 cytochrome c oxidase subunit III 240142 cyoC 1149587 cyoC Leptospira interrogans serovar Lai str. 56601 cytochrome c oxidase subunit III NP_710425.1 239498 D 189518 CDS NP_710428.1 24212947 1149590 241675..241974 1 NC_004342.2 hypothetical protein 241974 1149590 LA_0247 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710428.1 241675 D 189518 CDS NP_710429.1 24212948 1149591 242636..243313 1 NC_004342.2 hypothetical protein 243313 1149591 LA_0248 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710429.1 242636 D 189518 CDS NP_710430.2 294827601 1149592 243399..243944 1 NC_004342.2 transcriptional regulator 243944 1149592 LA_0249 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710430.2 243399 D 189518 CDS NP_710431.1 24212950 1149593 243986..245017 1 NC_004342.2 integral membrane protein with PIN domain 245017 1149593 LA_0250 Leptospira interrogans serovar Lai str. 56601 integral membrane protein with PIN domain NP_710431.1 243986 D 189518 CDS NP_710432.1 24212951 1149594 245079..246671 1 NC_004342.2 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 246671 pckA 1149594 pckA Leptospira interrogans serovar Lai str. 56601 phosphoenolpyruvate carboxykinase NP_710432.1 245079 D 189518 CDS NP_710434.1 24212953 1149596 complement(247506..248246) 1 NC_004342.2 hypothetical protein 248246 1149596 LA_0253 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710434.1 247506 R 189518 CDS NP_710435.2 294827602 1149597 complement(248283..249077) 1 NC_004342.2 hypothetical protein 249077 1149597 LA_0254 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710435.2 248283 R 189518 CDS NP_710436.1 24212955 1149598 complement(249070..249846) 1 NC_004342.2 ParA 249846 parA 1149598 parA Leptospira interrogans serovar Lai str. 56601 ParA NP_710436.1 249070 R 189518 CDS NP_710437.1 24212956 1149599 249960..251420 1 NC_004342.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 251420 gatB 1149599 gatB Leptospira interrogans serovar Lai str. 56601 aspartyl/glutamyl-tRNA amidotransferase subunit B NP_710437.1 249960 D 189518 CDS NP_710439.2 294827603 1149601 252876..256286 1 NC_004342.2 DNA polymerase III subunit alpha 256286 dnaE 1149601 dnaE Leptospira interrogans serovar Lai str. 56601 DNA polymerase III subunit alpha NP_710439.2 252876 D 189518 CDS NP_710440.1 24212959 1149602 complement(256385..256588) 1 NC_004342.2 hypothetical protein 256588 1149602 LA_0259 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710440.1 256385 R 189518 CDS NP_710442.2 294827604 1149604 complement(257323..258174) 1 NC_004342.2 M23 family metalloendopeptidase 258174 nlpD 1149604 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_710442.2 257323 R 189518 CDS NP_710443.2 294827605 1149605 258260..259165 1 NC_004342.2 RNA polymerase ECF-type sigma factor 259165 1149605 LA_0261 Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_710443.2 258260 D 189518 CDS NP_710444.1 24212963 1149606 259201..259929 1 NC_004342.2 hypothetical protein 259929 1149606 LA_0263 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710444.1 259201 D 189518 CDS NP_710447.1 24212966 1149609 261906..262592 1 NC_004342.2 hypothetical protein 262592 1149609 LA_0266 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710447.1 261906 D 189518 CDS NP_710449.2 294827606 1149611 complement(263604..263921) 1 NC_004342.2 hypothetical protein 263921 1149611 LA_0268 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710449.2 263604 R 189518 CDS NP_710450.2 294827607 1149612 complement(264684..265853) 1 NC_004342.2 ISlin1 transposase 265853 1149612 LA_0269 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710450.2 264684 R 189518 CDS NP_710452.1 24212971 1149614 complement(266483..267487) 1 NC_004342.2 hypothetical protein 267487 1149614 LA_0271 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710452.1 266483 R 189518 CDS NP_710453.1 24212972 1149615 complement(267500..268513) 1 NC_004342.2 hypothetical protein 268513 1149615 LA_0272 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710453.1 267500 R 189518 CDS NP_710454.2 294827608 1149616 268640..270013 1 NC_004342.2 lipoprotein releasing system permease 270013 lolE 1149616 lolE Leptospira interrogans serovar Lai str. 56601 lipoprotein releasing system permease NP_710454.2 268640 D 189518 CDS NP_710455.1 24212974 1149617 270015..270692 1 NC_004342.2 lipoprotein releasing system LolD 270692 1149617 LA_0274 Leptospira interrogans serovar Lai str. 56601 lipoprotein releasing system LolD NP_710455.1 270015 D 189518 CDS NP_710457.1 24212976 1149619 complement(271763..272434) 1 NC_004342.2 hypothetical protein 272434 1149619 LA_0276 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710457.1 271763 R 189518 CDS NP_710459.1 24212978 1149621 272966..273250 1 NC_004342.2 hypothetical protein 273250 1149621 LA_0278 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710459.1 272966 D 189518 CDS NP_710460.1 24212979 1149622 273468..274106 1 NC_004342.2 hypothetical protein 274106 1149622 LA_0279 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710460.1 273468 D 189518 CDS NP_710461.1 24212980 1149623 274192..275409 1 NC_004342.2 cAMP-binding protein 275409 crp 1149623 crp Leptospira interrogans serovar Lai str. 56601 cAMP-binding protein NP_710461.1 274192 D 189518 CDS NP_710462.1 24212981 1149624 275430..276116 1 NC_004342.2 3-methyl-adenine DNA glycosylase 276116 alkA 1149624 alkA Leptospira interrogans serovar Lai str. 56601 3-methyl-adenine DNA glycosylase NP_710462.1 275430 D 189518 CDS NP_710464.2 294827609 1149626 276968..278401 1 NC_004342.2 hypothetical protein 278401 1149626 LA_0283 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710464.2 276968 D 189518 CDS NP_710465.1 24212984 1149627 278475..279170 1 NC_004342.2 hypothetical protein 279170 1149627 LA_0284 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710465.1 278475 D 189518 CDS YP_003573287.1 294827610 9006873 279401..279817 1 NC_004342.2 hypothetical protein 279817 9006873 LA_0284a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573287.1 279401 D 189518 CDS NP_710467.1 24212986 1149629 280400..281158 1 NC_004342.2 hypothetical protein 281158 1149629 LA_0286 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710467.1 280400 D 189518 CDS NP_710469.2 294827611 1149631 complement(281861..282958) 1 NC_004342.2 guanylate cyclase 282958 1149631 LA_0288 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_710469.2 281861 R 189518 CDS NP_710470.1 24212989 1149632 complement(283181..283999) 1 NC_004342.2 guanylate cyclase 283999 1149632 LA_0289 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_710470.1 283181 R 189518 CDS NP_710472.1 24212991 1149634 284304..284750 1 NC_004342.2 ankyrin repeat-containing protein 284750 1149634 LA_0290 Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_710472.1 284304 D 189518 CDS NP_710473.1 24212992 1149635 284811..285992 1 NC_004342.2 tRNA (uracil-5-)-methyltransferase 285992 trmA 1149635 trmA Leptospira interrogans serovar Lai str. 56601 tRNA (uracil-5-)-methyltransferase NP_710473.1 284811 D 189518 CDS NP_710474.1 24212993 1149636 complement(287046..289361) 1 NC_004342.2 DNA double-strand break repair rad50 ATPase 289361 1149636 LA_0293 Leptospira interrogans serovar Lai str. 56601 DNA double-strand break repair rad50 ATPase NP_710474.1 287046 R 189518 CDS NP_710475.2 294827612 1149637 complement(289363..290448) 1 NC_004342.2 exonuclease 290448 1149637 LA_0294 Leptospira interrogans serovar Lai str. 56601 exonuclease NP_710475.2 289363 R 189518 CDS NP_710477.2 294827613 1149639 291025..292272 1 NC_004342.2 Zn-dependent alcohol dehydrogenase 292272 adhP 1149639 adhP Leptospira interrogans serovar Lai str. 56601 Zn-dependent alcohol dehydrogenase NP_710477.2 291025 D 189518 CDS NP_710478.1 24212997 1149640 complement(292402..293022) 1 NC_004342.2 CBS-domain-containing membrane protein 293022 1149640 LA_0297 Leptospira interrogans serovar Lai str. 56601 CBS-domain-containing membrane protein NP_710478.1 292402 R 189518 CDS NP_710479.1 24212998 1149641 complement(293024..293956) 1 NC_004342.2 hypothetical protein 293956 1149641 LA_0298 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710479.1 293024 R 189518 CDS NP_710480.1 24212999 1149642 294044..296149 1 NC_004342.2 carbon starvation protein A 296149 cstA 1149642 cstA Leptospira interrogans serovar Lai str. 56601 carbon starvation protein A NP_710480.1 294044 D 189518 CDS NP_710481.1 24213000 1149643 296146..296694 1 NC_004342.2 ADP-ribose pyrophosphatase 296694 1149643 LA_0300 Leptospira interrogans serovar Lai str. 56601 ADP-ribose pyrophosphatase NP_710481.1 296146 D 189518 CDS NP_710482.1 24213001 1149644 297002..298771 1 NC_004342.2 OmpA family protein 298771 1149644 LA_0301 Leptospira interrogans serovar Lai str. 56601 OmpA family protein NP_710482.1 297002 D 189518 CDS NP_710483.1 24213002 1149645 298777..299508 1 NC_004342.2 hypothetical protein 299508 1149645 LA_0302 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710483.1 298777 D 189518 CDS NP_710484.1 24213003 1149646 complement(299783..300136) 1 NC_004342.2 hypothetical protein 300136 1149646 LA_0303 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710484.1 299783 R 189518 CDS NP_710485.1 24213004 1149647 complement(300133..300465) 1 NC_004342.2 hypothetical protein 300465 1149647 LA_0304 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710485.1 300133 R 189518 CDS NP_710487.2 294827614 1149649 300812..301621 1 NC_004342.2 hypothetical protein 301621 1149649 LA_0306 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710487.2 300812 D 189518 CDS NP_710488.2 294827615 1149650 302284..303453 1 NC_004342.2 ISlin1 transposase 303453 1149650 LA_0307 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710488.2 302284 D 189518 CDS NP_710489.1 24213008 1149651 complement(304005..304865) 1 NC_004342.2 protoporphyrinogen oxidase 304865 hemK 1149651 hemK Leptospira interrogans serovar Lai str. 56601 protoporphyrinogen oxidase NP_710489.1 304005 R 189518 CDS NP_710490.1 24213009 1149652 complement(306151..306816) 1 NC_004342.2 cAMP-binding protein 306816 crp 1149652 crp Leptospira interrogans serovar Lai str. 56601 cAMP-binding protein NP_710490.1 306151 R 189518 CDS NP_710491.1 24213010 1149653 complement(306816..307871) 1 NC_004342.2 regulatory-like cAMP-binding protein 307871 1149653 LA_0310 Leptospira interrogans serovar Lai str. 56601 regulatory-like cAMP-binding protein NP_710491.1 306816 R 189518 CDS NP_710492.1 24213011 1149654 complement(307882..309132) 1 NC_004342.2 metal-dependent hydrolase 309132 1149654 LA_0311 Leptospira interrogans serovar Lai str. 56601 metal-dependent hydrolase NP_710492.1 307882 R 189518 CDS NP_710493.1 24213012 1149655 complement(309151..309816) 1 NC_004342.2 cell wall hydrolase 309816 1149655 LA_0312 Leptospira interrogans serovar Lai str. 56601 cell wall hydrolase NP_710493.1 309151 R 189518 CDS NP_710494.1 24213013 1149656 complement(310065..312185) 1 NC_004342.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 312185 fusA 1149656 fusA Leptospira interrogans serovar Lai str. 56601 elongation factor G NP_710494.1 310065 R 189518 CDS YP_003573288.1 294827616 9006874 312212..312403 1 NC_004342.2 hypothetical protein 312403 9006874 LA_0313a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573288.1 312212 D 189518 CDS NP_710495.1 24213014 1149657 312472..314091 1 NC_004342.2 potassium uptake transporter 314091 trkG 1149657 trkG Leptospira interrogans serovar Lai str. 56601 potassium uptake transporter NP_710495.1 312472 D 189518 CDS NP_710496.2 294827617 1149658 complement(314350..314694) 1 NC_004342.2 transcriptional regulator 314694 1149658 LA_0316 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710496.2 314350 R 189518 CDS NP_710498.2 294827618 1149660 314751..314969 1 NC_004342.2 XRE family transcriptional regulator 314969 1149660 LA_0317 Leptospira interrogans serovar Lai str. 56601 XRE family transcriptional regulator NP_710498.2 314751 D 189518 CDS NP_710499.1 24213018 1149661 complement(315155..315361) 1 NC_004342.2 hypothetical protein 315361 1149661 LA_0318 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710499.1 315155 R 189518 CDS NP_710500.1 24213019 1149662 316394..317293 1 NC_004342.2 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase 317293 1149662 LA_0319 Leptospira interrogans serovar Lai str. 56601 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase NP_710500.1 316394 D 189518 CDS NP_710501.1 24213020 1149663 318008..318511 1 NC_004342.2 thioredoxin 318511 1149663 LA_0320 Leptospira interrogans serovar Lai str. 56601 thioredoxin NP_710501.1 318008 D 189518 CDS NP_710502.1 24213021 1149664 319295..320065 1 NC_004342.2 hypothetical protein 320065 1149664 LA_0321 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710502.1 319295 D 189518 CDS NP_710503.2 294827619 1149665 complement(320236..320598) 1 NC_004342.2 fibronectin binding protein 320598 1149665 LA_0322 Leptospira interrogans serovar Lai str. 56601 fibronectin binding protein NP_710503.2 320236 R 189518 CDS NP_710504.2 294827620 1149666 321257..321685 1 NC_004342.2 hypothetical protein 321685 1149666 LA_0323 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710504.2 321257 D 189518 CDS NP_710506.1 24213025 1149668 322365..323387 1 NC_004342.2 Zn-dependent alcohol dehydrogenase 323387 adhP 1149668 adhP Leptospira interrogans serovar Lai str. 56601 Zn-dependent alcohol dehydrogenase NP_710506.1 322365 D 189518 CDS NP_710507.2 294827621 1149669 323709..324650 1 NC_004342.2 geranylgeranyl pyrophosphate synthase 324650 ispA 1149669 ispA Leptospira interrogans serovar Lai str. 56601 geranylgeranyl pyrophosphate synthase NP_710507.2 323709 D 189518 CDS NP_710508.2 294827622 1149670 324631..325410 1 NC_004342.2 hemolysin A 325410 1149670 LA_0327 Leptospira interrogans serovar Lai str. 56601 hemolysin A NP_710508.2 324631 D 189518 CDS NP_710509.1 24213028 1149671 325613..326839 1 NC_004342.2 acetyltransferase 326839 1149671 LA_0328 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_710509.1 325613 D 189518 CDS NP_710511.1 24213030 1149673 complement(327237..329753) 1 NC_004342.2 penicillin G acylase precursor 329753 1149673 LA_0330 Leptospira interrogans serovar Lai str. 56601 penicillin G acylase precursor NP_710511.1 327237 R 189518 CDS NP_710513.1 24213032 1149675 331267..331653 1 NC_004342.2 6-pyruvoyl tetrahydrobiopterin synthase 331653 1149675 LA_0332 Leptospira interrogans serovar Lai str. 56601 6-pyruvoyl tetrahydrobiopterin synthase NP_710513.1 331267 D 189518 CDS NP_710514.1 24213033 1149676 331663..332391 1 NC_004342.2 PP-loop superfamily ATPase 332391 1149676 LA_0333 Leptospira interrogans serovar Lai str. 56601 PP-loop superfamily ATPase NP_710514.1 331663 D 189518 CDS NP_710515.1 24213034 1149677 332469..332753 1 NC_004342.2 proton-translocating transhydrogenase subunit alpha 332753 1149677 LA_0334 Leptospira interrogans serovar Lai str. 56601 proton-translocating transhydrogenase subunit alpha NP_710515.1 332469 D 189518 CDS NP_710516.1 24213035 1149678 332756..334156 1 NC_004342.2 NAD(P)(+) transhydrogenase subunit beta 334156 pntB 1149678 pntB Leptospira interrogans serovar Lai str. 56601 NAD(P)(+) transhydrogenase subunit beta NP_710516.1 332756 D 189518 CDS NP_710518.1 24213037 1149680 335631..336134 1 NC_004342.2 hypothetical protein 336134 1149680 LA_0337 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710518.1 335631 D 189518 CDS NP_710519.2 294827623 1149681 336520..336792 1 NC_004342.2 hypothetical protein 336792 1149681 LA_0338 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710519.2 336520 D 189518 CDS NP_710520.2 294827624 1149682 complement(336924..337895) 1 NC_004342.2 glycerophosphoryl diester phosphodiesterase 337895 glpQ 1149682 glpQ Leptospira interrogans serovar Lai str. 56601 glycerophosphoryl diester phosphodiesterase NP_710520.2 336924 R 189518 CDS NP_710522.1 24213041 1149684 339180..339668 1 NC_004342.2 hypothetical protein 339668 glcG 1149684 glcG Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710522.1 339180 D 189518 CDS NP_710524.1 24213043 1149686 complement(340441..340848) 1 NC_004342.2 hypothetical protein 340848 1149686 LA_0343 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710524.1 340441 R 189518 CDS NP_710526.1 24213045 1149688 complement(341672..342055) 1 NC_004342.2 forms a junction between the M-ring and FlgB during the flagella biosynthesis; flagellar hook-basal body protein FliE 342055 fliE 1149688 fliE Leptospira interrogans serovar Lai str. 56601 flagellar hook-basal body protein FliE NP_710526.1 341672 R 189518 CDS NP_710527.2 294827625 1149689 complement(342058..342519) 1 NC_004342.2 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 342519 flgC 1149689 flgC Leptospira interrogans serovar Lai str. 56601 flagellar basal body rod protein FlgC NP_710527.2 342058 R 189518 CDS NP_710528.1 24213047 1149690 complement(342585..343016) 1 NC_004342.2 with FlgF and C makes up the proximal portion of the flagellar basal body rod; flagellar basal-body rod protein FlgB 343016 flgB 1149690 flgB Leptospira interrogans serovar Lai str. 56601 flagellar basal-body rod protein FlgB NP_710528.1 342585 R 189518 CDS NP_710530.1 24213049 1149692 343138..343428 1 NC_004342.2 anti-sigma factor antagonist 343428 1149692 LA_0348 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_710530.1 343138 D 189518 CDS NP_710531.1 24213050 1149693 343825..344166 1 NC_004342.2 hypothetical protein 344166 1149693 LA_0350 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710531.1 343825 D 189518 CDS NP_710532.1 24213051 1149694 344199..345248 1 NC_004342.2 TPR-repeat-containing protein 345248 1149694 LA_0351 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710532.1 344199 D 189518 CDS NP_710533.1 24213052 1149695 345446..346687 1 NC_004342.2 hypothetical protein 346687 1149695 LA_0352 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710533.1 345446 D 189518 CDS NP_710534.2 294827626 1149696 complement(346777..347193) 1 NC_004342.2 hypothetical protein 347193 1149696 LA_0353 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710534.2 346777 R 189518 CDS NP_710536.1 24213055 1149698 complement(347649..348029) 1 NC_004342.2 hypothetical protein 348029 1149698 LA_0355 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710536.1 347649 R 189518 CDS NP_710538.1 24213057 1149700 complement(348314..349291) 1 NC_004342.2 dienelactone hydrolase family protein 349291 1149700 LA_0357 Leptospira interrogans serovar Lai str. 56601 dienelactone hydrolase family protein NP_710538.1 348314 R 189518 CDS NP_710539.1 24213058 1149701 349937..350632 1 NC_004342.2 hypothetical protein 350632 1149701 LA_0358 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710539.1 349937 D 189518 CDS NP_710541.1 24213060 1149703 complement(351774..354668) 1 NC_004342.2 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 354668 gcvP 1149703 gcvP Leptospira interrogans serovar Lai str. 56601 glycine dehydrogenase NP_710541.1 351774 R 189518 CDS NP_710542.1 24213061 1149704 complement(354708..355100) 1 NC_004342.2 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 355100 gcvH 1149704 gcvH Leptospira interrogans serovar Lai str. 56601 glycine cleavage system protein H NP_710542.1 354708 R 189518 CDS NP_710543.3 294827627 1149705 complement(355118..356308) 1 NC_004342.2 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 356308 gcvT 1149705 gcvT Leptospira interrogans serovar Lai str. 56601 glycine cleavage system aminomethyltransferase T NP_710543.3 355118 R 189518 CDS NP_710544.2 294827628 1149706 357085..357258 1 NC_004342.2 hypothetical protein 357258 1149706 LA_0363 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710544.2 357085 D 189518 CDS NP_710545.2 294827629 1149707 357740..358069 1 NC_004342.2 hypothetical protein 358069 1149707 LA_0364 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710545.2 357740 D 189518 CDS NP_710546.1 24213065 1149708 complement(358339..360000) 1 NC_004342.2 hypothetical protein 360000 1149708 LA_0365 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710546.1 358339 R 189518 CDS NP_710548.3 294827630 1149710 360124..361251 1 NC_004342.2 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 361251 serC 1149710 serC Leptospira interrogans serovar Lai str. 56601 phosphoserine aminotransferase NP_710548.3 360124 D 189518 CDS NP_710549.2 294827631 1149711 361251..361850 1 NC_004342.2 hypothetical protein 361850 1149711 LA_0368 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710549.2 361251 D 189518 CDS NP_710550.1 24213069 1149712 362337..362774 1 NC_004342.2 ribose-5-phosphate isomerase 362774 rpiB 1149712 rpiB Leptospira interrogans serovar Lai str. 56601 ribose-5-phosphate isomerase NP_710550.1 362337 D 189518 CDS NP_710551.2 294827632 1149713 363018..364751 1 NC_004342.2 hypothetical protein 364751 1149713 LA_0370 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710551.2 363018 D 189518 CDS NP_710552.1 24213071 1149714 complement(364713..365129) 1 NC_004342.2 hypothetical protein 365129 1149714 LA_0371 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710552.1 364713 R 189518 CDS NP_710553.1 24213072 1149715 complement(365126..365314) 1 NC_004342.2 hypothetical protein 365314 1149715 LA_0372 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710553.1 365126 R 189518 CDS NP_710554.2 294827633 1149716 complement(365314..365886) 1 NC_004342.2 hypothetical protein 365886 1149716 LA_0373 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710554.2 365314 R 189518 CDS NP_710555.1 24213074 1149717 complement(365936..368026) 1 NC_004342.2 hypothetical protein 368026 1149717 LA_0374 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710555.1 365936 R 189518 CDS NP_710556.1 24213075 1149718 complement(368023..368955) 1 NC_004342.2 hypothetical protein 368955 1149718 LA_0375 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710556.1 368023 R 189518 CDS NP_710557.1 24213076 1149719 369068..370039 1 NC_004342.2 hypothetical protein 370039 1149719 LA_0376 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710557.1 369068 D 189518 CDS NP_710558.1 24213077 1149720 370212..370601 1 NC_004342.2 hypothetical protein 370601 1149720 LA_0377 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710558.1 370212 D 189518 CDS NP_710559.2 294827634 1149721 complement(370714..371850) 1 NC_004342.2 TPR-repeat-containing protein 371850 1149721 LA_0378 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710559.2 370714 R 189518 CDS NP_710560.2 294827635 1149722 complement(371847..373382) 1 NC_004342.2 hypothetical protein 373382 1149722 LA_0379 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710560.2 371847 R 189518 CDS NP_710561.1 24213080 1149723 373620..374414 1 NC_004342.2 methyltransferase 374414 1149723 LA_0380 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_710561.1 373620 D 189518 CDS NP_710562.2 294827636 1149724 complement(374655..374894) 1 NC_004342.2 hypothetical protein 374894 1149724 LA_0381 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710562.2 374655 R 189518 CDS NP_710563.1 24213082 1149725 complement(375156..376058) 1 NC_004342.2 hypothetical protein 376058 1149725 LA_0382 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710563.1 375156 R 189518 CDS NP_710564.1 24213083 1149726 complement(376135..376716) 1 NC_004342.2 hypothetical protein 376716 1149726 LA_0383 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710564.1 376135 R 189518 CDS NP_710565.1 24213084 1149727 complement(377190..378578) 1 NC_004342.2 glycosyltransferase 378578 wcaJ 1149727 wcaJ Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_710565.1 377190 R 189518 CDS NP_710566.1 24213085 1149728 378657..379418 1 NC_004342.2 two-component response regulator receiver protein 379418 1149728 LA_0385 Leptospira interrogans serovar Lai str. 56601 two-component response regulator receiver protein NP_710566.1 378657 D 189518 CDS NP_710567.2 294827637 1149729 379408..381597 1 NC_004342.2 histidine kinase 381597 1149729 LA_0386 Leptospira interrogans serovar Lai str. 56601 histidine kinase NP_710567.2 379408 D 189518 CDS NP_710568.2 294827638 1149730 381615..382226 1 NC_004342.2 hypothetical protein 382226 1149730 LA_0387 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710568.2 381615 D 189518 CDS NP_710569.1 24213088 1149731 complement(382317..383630) 1 NC_004342.2 2-methylthioadenine synthetase 383630 miaB 1149731 miaB Leptospira interrogans serovar Lai str. 56601 2-methylthioadenine synthetase NP_710569.1 382317 R 189518 CDS NP_710570.2 294827639 1149732 complement(383611..384525) 1 NC_004342.2 hypothetical protein 384525 1149732 LA_0389 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710570.2 383611 R 189518 CDS NP_710571.1 24213090 1149733 complement(384742..385167) 1 NC_004342.2 hypothetical protein 385167 1149733 LA_0390 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710571.1 384742 R 189518 CDS NP_710572.1 24213091 1149734 complement(385170..387710) 1 NC_004342.2 ATP-dependent protease ClpA 387710 clpA 1149734 clpA Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease ClpA NP_710572.1 385170 R 189518 CDS NP_710573.1 24213092 1149735 complement(387855..388655) 1 NC_004342.2 hypothetical protein 388655 1149735 LA_0392 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710573.1 387855 R 189518 CDS NP_710574.1 24213093 1149736 complement(389037..389222) 1 NC_004342.2 hypothetical protein 389222 1149736 LA_0393 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710574.1 389037 R 189518 CDS NP_710575.2 294827640 1149737 390275..390853 1 NC_004342.2 integrase/recombinase 390853 1149737 LA_0394 Leptospira interrogans serovar Lai str. 56601 integrase/recombinase NP_710575.2 390275 D 189518 CDS NP_710576.1 24213095 1149738 390918..391184 1 NC_004342.2 anti-sigma factor antagonist 391184 1149738 LA_0395 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_710576.1 390918 D 189518 CDS YP_003573289.1 294827641 9006875 391141..391254 1 NC_004342.2 anti-sigma factor antagonist 391254 9006875 LA_0395a Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist YP_003573289.1 391141 D 189518 CDS NP_710577.2 294827642 1149739 391282..392778 1 NC_004342.2 ArnT-like protein 392778 1149739 LA_0396 Leptospira interrogans serovar Lai str. 56601 ArnT-like protein NP_710577.2 391282 D 189518 CDS NP_710578.1 24213097 1149740 392775..393425 1 NC_004342.2 lipase/esterase 393425 1149740 LA_0397 Leptospira interrogans serovar Lai str. 56601 lipase/esterase NP_710578.1 392775 D 189518 CDS NP_710580.1 24213099 1149742 complement(394069..395130) 1 NC_004342.2 paraoxonase 395130 1149742 LA_0399 Leptospira interrogans serovar Lai str. 56601 paraoxonase NP_710580.1 394069 R 189518 CDS NP_710581.2 294827643 1149743 395280..395537 1 NC_004342.2 hypothetical protein 395537 1149743 LA_0400 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710581.2 395280 D 189518 CDS NP_710582.1 24213101 1149744 complement(397402..397884) 1 NC_004342.2 phosphohistidine phosphatase 397884 1149744 LA_0401 Leptospira interrogans serovar Lai str. 56601 phosphohistidine phosphatase NP_710582.1 397402 R 189518 CDS NP_710583.1 24213102 1149745 398092..399006 1 NC_004342.2 ABC transporter ATP-binding protein 399006 ccmA 1149745 ccmA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_710583.1 398092 D 189518 CDS NP_710584.1 24213103 1149746 398999..399823 1 NC_004342.2 ABC transporter permease 399823 1149746 LA_0403 Leptospira interrogans serovar Lai str. 56601 ABC transporter permease NP_710584.1 398999 D 189518 CDS NP_710585.1 24213104 1149747 399907..401418 1 NC_004342.2 HD family protein 401418 1149747 LA_0404 Leptospira interrogans serovar Lai str. 56601 HD family protein NP_710585.1 399907 D 189518 CDS NP_710586.2 294827644 1149748 complement(401415..402320) 1 NC_004342.2 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 402320 ksgA 1149748 ksgA Leptospira interrogans serovar Lai str. 56601 dimethyladenosine transferase NP_710586.2 401415 R 189518 CDS NP_710587.1 24213106 1149749 complement(402283..404592) 1 NC_004342.2 hypothetical protein 404592 1149749 LA_0406 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710587.1 402283 R 189518 CDS NP_710588.1 24213107 1149750 complement(404648..404845) 1 NC_004342.2 hypothetical protein 404845 1149750 LA_0407 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710588.1 404648 R 189518 CDS NP_710589.1 24213108 1149751 complement(405457..406425) 1 NC_004342.2 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 406425 trpS 1149751 trpS Leptospira interrogans serovar Lai str. 56601 tryptophanyl-tRNA synthetase NP_710589.1 405457 R 189518 CDS NP_710590.1 24213109 1149752 complement(406422..408242) 1 NC_004342.2 hypothetical protein 408242 1149752 LA_0409 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710590.1 406422 R 189518 CDS NP_710591.1 24213110 1149753 complement(408248..408841) 1 NC_004342.2 outer membrane lipoprotein-sorting protein 408841 1149753 LA_0410 Leptospira interrogans serovar Lai str. 56601 outer membrane lipoprotein-sorting protein NP_710591.1 408248 R 189518 CDS NP_710592.1 24213111 1149754 complement(408966..409925) 1 NC_004342.2 electron transfer flavoprotein subunit alpha 409925 etfA 1149754 etfA Leptospira interrogans serovar Lai str. 56601 electron transfer flavoprotein subunit alpha NP_710592.1 408966 R 189518 CDS NP_710593.1 24213112 1149755 complement(409937..410698) 1 NC_004342.2 electron transfer flavoprotein subunit beta 410698 etfB 1149755 etfB Leptospira interrogans serovar Lai str. 56601 electron transfer flavoprotein subunit beta NP_710593.1 409937 R 189518 CDS NP_710594.1 24213113 1149756 complement(410781..411203) 1 NC_004342.2 hypothetical protein 411203 1149756 LA_0413 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710594.1 410781 R 189518 CDS NP_710595.1 24213114 1149757 411261..412445 1 NC_004342.2 isovaleryl-CoA dehydrogenase 412445 ivd 1149757 ivd Leptospira interrogans serovar Lai str. 56601 isovaleryl-CoA dehydrogenase NP_710595.1 411261 D 189518 CDS NP_710596.1 24213115 1149758 412442..413137 1 NC_004342.2 SAM-dependent O-methyltransferase 413137 1149758 LA_0415 Leptospira interrogans serovar Lai str. 56601 SAM-dependent O-methyltransferase NP_710596.1 412442 D 189518 CDS NP_710597.1 24213116 1149759 complement(413199..414278) 1 NC_004342.2 hypothetical protein 414278 1149759 LA_0416 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710597.1 413199 R 189518 CDS NP_710598.2 294827645 1149760 414588..415058 1 NC_004342.2 SAM-dependent O-methyltransferase 415058 1149760 LA_0417 Leptospira interrogans serovar Lai str. 56601 SAM-dependent O-methyltransferase NP_710598.2 414588 D 189518 CDS NP_710599.2 294827646 1149761 415525..416694 1 NC_004342.2 ISlin1 transposase 416694 1149761 LA_0418 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710599.2 415525 D 189518 CDS NP_710600.1 24213119 1149762 complement(416822..417370) 1 NC_004342.2 hypothetical protein 417370 1149762 LA_0419 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710600.1 416822 R 189518 CDS NP_710601.1 24213120 1149763 complement(418144..418689) 1 NC_004342.2 hypothetical protein 418689 1149763 LA_0420 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710601.1 418144 R 189518 CDS NP_710602.1 24213121 1149764 complement(418767..419309) 1 NC_004342.2 hypothetical protein 419309 1149764 LA_0421 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710602.1 418767 R 189518 CDS NP_710604.1 24213123 1149766 complement(420482..421924) 1 NC_004342.2 hypothetical protein 421924 1149766 LA_0423 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710604.1 420482 R 189518 CDS NP_710606.1 24213125 1149768 complement(422644..423885) 1 NC_004342.2 hypothetical protein 423885 1149768 LA_0425 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710606.1 422644 R 189518 CDS NP_710607.1 24213126 1149769 complement(424080..425630) 1 NC_004342.2 hypothetical protein 425630 1149769 LA_0426 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710607.1 424080 R 189518 CDS NP_710608.1 24213127 1149770 complement(426298..427017) 1 NC_004342.2 polyphosphate kinase 427017 1149770 LA_0427 Leptospira interrogans serovar Lai str. 56601 polyphosphate kinase NP_710608.1 426298 R 189518 CDS NP_710609.1 24213128 1149771 complement(427035..427721) 1 NC_004342.2 transcriptional regulator 427721 1149771 LA_0428 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710609.1 427035 R 189518 CDS NP_710610.2 294827647 1149772 complement(427730..428563) 1 NC_004342.2 hypothetical protein 428563 1149772 LA_0429 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710610.2 427730 R 189518 CDS NP_710611.2 294827648 1149773 429645..430379 1 NC_004342.2 hypothetical protein 430379 1149773 LA_0430 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710611.2 429645 D 189518 CDS NP_710612.2 294827649 1149774 431437..431784 1 NC_004342.2 transcriptional regulator 431784 1149774 LA_0431 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710612.2 431437 D 189518 CDS NP_710613.2 294827650 1149775 431787..432293 1 NC_004342.2 hypothetical protein 432293 1149775 LA_0432 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710613.2 431787 D 189518 CDS NP_710614.1 24213133 1149776 432301..432846 1 NC_004342.2 hypothetical protein 432846 1149776 LA_0433 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710614.1 432301 D 189518 CDS NP_710615.2 294827651 1149777 complement(433189..433395) 1 NC_004342.2 hypothetical protein 433395 1149777 LA_0434 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710615.2 433189 R 189518 CDS NP_710619.1 24213138 1149781 complement(434216..435913) 1 NC_004342.2 acyl-CoA dehydrogenase 435913 1149781 LA_0438 Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_710619.1 434216 R 189518 CDS NP_710620.2 294827652 1149782 complement(436509..438155) 1 NC_004342.2 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 438155 gpmI 1149782 gpmI Leptospira interrogans serovar Lai str. 56601 phosphoglyceromutase NP_710620.2 436509 R 189518 CDS NP_710622.1 24213141 1149784 438546..440564 1 NC_004342.2 hypothetical protein 440564 1149784 LA_0441 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710622.1 438546 D 189518 CDS NP_710623.2 294827653 1149785 complement(441229..442071) 1 NC_004342.2 hypothetical protein 442071 1149785 LA_0442 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710623.2 441229 R 189518 CDS NP_710624.1 24213143 1149786 442175..442723 1 NC_004342.2 RNA polymerase sigma subunit 442723 1149786 LA_0443 Leptospira interrogans serovar Lai str. 56601 RNA polymerase sigma subunit NP_710624.1 442175 D 189518 CDS NP_710625.2 294827654 1149787 442883..443932 1 NC_004342.2 hypothetical protein 443932 1149787 LA_0444 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710625.2 442883 D 189518 CDS NP_710627.2 294827655 1149789 complement(445410..445859) 1 NC_004342.2 hypothetical protein 445859 1149789 LA_0446 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710627.2 445410 R 189518 CDS NP_710628.1 24213147 1149790 447171..447341 1 NC_004342.2 hypothetical protein 447341 1149790 LA_0447 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710628.1 447171 D 189518 CDS NP_710629.2 294827656 1149791 447458..449353 1 NC_004342.2 ABC transporter ATPase 449353 uup 1149791 uup Leptospira interrogans serovar Lai str. 56601 ABC transporter ATPase NP_710629.2 447458 D 189518 CDS NP_710630.2 294827657 1149792 449857..450192 1 NC_004342.2 rhodanese-like protein 450192 pspE 1149792 pspE Leptospira interrogans serovar Lai str. 56601 rhodanese-like protein NP_710630.2 449857 D 189518 CDS NP_710631.2 294827658 1149793 450695..451513 1 NC_004342.2 phosphohydrolase 451513 1149793 LA_0450 Leptospira interrogans serovar Lai str. 56601 phosphohydrolase NP_710631.2 450695 D 189518 CDS NP_710632.2 294827659 1149794 complement(452242..453411) 1 NC_004342.2 ISlin1 transposase 453411 1149794 LA_0451 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710632.2 452242 R 189518 CDS NP_710633.1 24213152 1149795 complement(453818..454012) 1 NC_004342.2 hypothetical protein 454012 1149795 LA_0452 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710633.1 453818 R 189518 CDS NP_710636.1 24213155 1149798 complement(454834..455445) 1 NC_004342.2 transcriptional regulator 455445 1149798 LA_0455 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710636.1 454834 R 189518 CDS NP_710638.1 24213157 1149800 456315..457496 1 NC_004342.2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 457496 paaJ 1149800 paaJ Leptospira interrogans serovar Lai str. 56601 acetyl-CoA acetyltransferase NP_710638.1 456315 D 189518 CDS NP_710639.1 24213158 1149801 457607..458041 1 NC_004342.2 hypothetical protein 458041 1149801 LA_0458 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710639.1 457607 D 189518 CDS NP_710640.1 24213159 1149802 complement(458138..459475) 1 NC_004342.2 N-acetylmuramoyl-L-alanine amidase 459475 1149802 LA_0459 Leptospira interrogans serovar Lai str. 56601 N-acetylmuramoyl-L-alanine amidase NP_710640.1 458138 R 189518 CDS NP_710641.1 24213160 1149803 complement(459472..460053) 1 NC_004342.2 hypothetical protein 460053 1149803 LA_0460 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710641.1 459472 R 189518 CDS NP_710642.1 24213161 1149804 460164..460325 1 NC_004342.2 hypothetical protein 460325 1149804 LA_0461 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710642.1 460164 D 189518 CDS NP_710643.1 24213162 1149805 complement(460531..461337) 1 NC_004342.2 hypothetical protein 461337 1149805 LA_0462 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710643.1 460531 R 189518 CDS NP_710644.1 24213163 1149806 461447..461902 1 NC_004342.2 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 461902 ribH 1149806 ribH Leptospira interrogans serovar Lai str. 56601 6,7-dimethyl-8-ribityllumazine synthase NP_710644.1 461447 D 189518 CDS NP_710645.1 24213164 1149807 461903..462319 1 NC_004342.2 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 462319 nusB 1149807 nusB Leptospira interrogans serovar Lai str. 56601 transcription antitermination protein NusB NP_710645.1 461903 D 189518 CDS NP_710646.1 24213165 1149808 462312..464378 1 NC_004342.2 TPR-repeat-containing protein 464378 1149808 LA_0465 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710646.1 462312 D 189518 CDS NP_710647.1 24213166 1149809 464399..465715 1 NC_004342.2 FOG:HEAT repeat protein 465715 1149809 LA_0466 Leptospira interrogans serovar Lai str. 56601 FOG:HEAT repeat protein NP_710647.1 464399 D 189518 CDS NP_710648.1 24213167 1149810 complement(466307..467161) 1 NC_004342.2 hypothetical protein 467161 1149810 LA_0467 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710648.1 466307 R 189518 CDS NP_710650.1 24213169 1149812 468422..469708 1 NC_004342.2 isopropylmalate/homocitrate/citramalate synthase 469708 leuA 1149812 leuA Leptospira interrogans serovar Lai str. 56601 isopropylmalate/homocitrate/citramalate synthase NP_710650.1 468422 D 189518 CDS NP_710652.1 24213171 1149814 complement(470147..470620) 1 NC_004342.2 hypothetical protein 470620 1149814 LA_0471 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710652.1 470147 R 189518 CDS NP_710655.1 24213174 1149817 471382..472542 1 NC_004342.2 permease 472542 1149817 LA_0474 Leptospira interrogans serovar Lai str. 56601 permease NP_710655.1 471382 D 189518 CDS NP_710658.1 24213177 1149820 473644..475065 1 NC_004342.2 Tdh-like protein 475065 1149820 LA_0477 Leptospira interrogans serovar Lai str. 56601 Tdh-like protein NP_710658.1 473644 D 189518 CDS NP_710659.2 294827660 1149821 complement(475613..476131) 1 NC_004342.2 hypothetical protein 476131 1149821 LA_0478 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710659.2 475613 R 189518 CDS NP_710660.2 294827661 1149822 476130..476381 1 NC_004342.2 hypothetical protein 476381 1149822 LA_0479 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710660.2 476130 D 189518 CDS NP_710663.1 24213182 1149825 complement(477157..477372) 1 NC_004342.2 hypothetical protein 477372 1149825 LA_0482 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710663.1 477157 R 189518 CDS NP_710665.2 294827662 1149827 477484..478530 1 NC_004342.2 transcriptional regulator 478530 1149827 LA_0484 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710665.2 477484 D 189518 CDS NP_710669.1 24213188 1149831 complement(480062..481363) 1 NC_004342.2 DNA helicase UvrD 481363 uvrD 1149831 uvrD Leptospira interrogans serovar Lai str. 56601 DNA helicase UvrD NP_710669.1 480062 R 189518 CDS NP_710670.2 294827663 1149832 complement(481854..483023) 1 NC_004342.2 ISlin1 transposase 483023 1149832 LA_0489 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710670.2 481854 R 189518 CDS NP_710673.2 294827664 1149835 484446..485531 1 NC_004342.2 hypothetical protein 485531 lipL36 1149835 lipL36 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710673.2 484446 D 189518 CDS NP_710675.1 24213194 1149837 complement(486857..487552) 1 NC_004342.2 hypothetical protein 487552 1149837 LA_0494 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710675.1 486857 R 189518 CDS NP_710676.1 24213195 1149838 489179..489571 1 NC_004342.2 hypothetical protein 489571 1149838 LA_0495 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710676.1 489179 D 189518 CDS NP_710677.1 24213196 1149839 490101..490457 1 NC_004342.2 hypothetical protein 490457 1149839 LA_0496 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710677.1 490101 D 189518 CDS NP_710679.1 24213198 1149841 complement(491129..491800) 1 NC_004342.2 flagellar motor protein 491800 1149841 LA_0498 Leptospira interrogans serovar Lai str. 56601 flagellar motor protein NP_710679.1 491129 R 189518 CDS NP_710681.1 24213200 1149843 491931..492608 1 NC_004342.2 hypothetical protein 492608 1149843 LA_0500 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710681.1 491931 D 189518 CDS NP_710682.1 24213201 1149844 complement(492769..492987) 1 NC_004342.2 hypothetical protein 492987 1149844 LA_0501 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710682.1 492769 R 189518 CDS NP_710683.1 24213202 1149845 493397..494494 1 NC_004342.2 fatty acid desaturase 494494 1149845 LA_0502 Leptospira interrogans serovar Lai str. 56601 fatty acid desaturase NP_710683.1 493397 D 189518 CDS NP_710684.2 294827665 1149846 complement(495579..496667) 1 NC_004342.2 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 496667 dinP 1149846 dinP Leptospira interrogans serovar Lai str. 56601 DNA polymerase IV NP_710684.2 495579 R 189518 CDS NP_710685.1 24213204 1149847 complement(496695..497450) 1 NC_004342.2 ComFC-like protein 497450 1149847 LA_0504 Leptospira interrogans serovar Lai str. 56601 ComFC-like protein NP_710685.1 496695 R 189518 CDS NP_710686.1 24213205 1149848 complement(497544..498644) 1 NC_004342.2 hypothetical protein 498644 1149848 LA_0505 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710686.1 497544 R 189518 CDS NP_710687.2 294827666 1149849 498822..499406 1 NC_004342.2 hypothetical protein 499406 1149849 LA_0506 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710687.2 498822 D 189518 CDS NP_710690.1 24213209 1149852 500507..501001 1 NC_004342.2 hypothetical protein 501001 1149852 LA_0509 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710690.1 500507 D 189518 CDS NP_710692.1 24213211 1149854 501708..502004 1 NC_004342.2 transcriptional regulator 502004 1149854 LA_0511 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710692.1 501708 D 189518 CDS NP_710694.1 24213213 1149856 502621..503643 1 NC_004342.2 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 503643 lpxD 1149856 lpxD Leptospira interrogans serovar Lai str. 56601 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_710694.1 502621 D 189518 CDS NP_710695.1 24213214 1149857 504548..505438 1 NC_004342.2 drug/metabolite transporter 505438 1149857 LA_0514 Leptospira interrogans serovar Lai str. 56601 drug/metabolite transporter NP_710695.1 504548 D 189518 CDS NP_710696.1 24213215 1149858 505702..506940 1 NC_004342.2 flavoprotein 506940 1149858 LA_0515 Leptospira interrogans serovar Lai str. 56601 flavoprotein NP_710696.1 505702 D 189518 CDS NP_710698.1 24213217 1149860 complement(507175..507510) 1 NC_004342.2 hypothetical protein 507510 1149860 LA_0517 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710698.1 507175 R 189518 CDS NP_710699.1 24213218 1149861 complement(507507..507785) 1 NC_004342.2 acetyltransferase 507785 1149861 LA_0518 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_710699.1 507507 R 189518 CDS NP_710701.1 24213220 1149863 complement(508488..508931) 1 NC_004342.2 hypothetical protein 508931 1149863 LA_0520 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710701.1 508488 R 189518 CDS NP_710703.1 24213222 1149865 complement(509364..509813) 1 NC_004342.2 MarR family transcriptional regulator 509813 marR 1149865 marR Leptospira interrogans serovar Lai str. 56601 MarR family transcriptional regulator NP_710703.1 509364 R 189518 CDS NP_710704.1 24213223 1149866 509908..511134 1 NC_004342.2 pseudouridine synthase 511134 1149866 LA_0523 Leptospira interrogans serovar Lai str. 56601 pseudouridine synthase NP_710704.1 509908 D 189518 CDS NP_710705.2 294827667 1149867 512035..513432 1 NC_004342.2 amino acid transporter 513432 1149867 LA_0524 Leptospira interrogans serovar Lai str. 56601 amino acid transporter NP_710705.2 512035 D 189518 CDS NP_710706.1 24213225 1149868 513456..513839 1 NC_004342.2 hypothetical protein 513839 1149868 LA_0525 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710706.1 513456 D 189518 CDS NP_710711.1 24213230 1149873 complement(520396..521676) 1 NC_004342.2 glycosyl hydrolase 521676 1149873 LA_0530 Leptospira interrogans serovar Lai str. 56601 glycosyl hydrolase NP_710711.1 520396 R 189518 CDS NP_710713.1 24213232 1149875 523412..524311 1 NC_004342.2 hypothetical protein 524311 1149875 LA_0532 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710713.1 523412 D 189518 CDS NP_710714.1 24213233 1149876 525208..526317 1 NC_004342.2 pyridoxal phosphate-dependent aminotransferase 526317 wecE 1149876 wecE Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate-dependent aminotransferase NP_710714.1 525208 D 189518 CDS NP_710715.1 24213234 1149877 527584..528174 1 NC_004342.2 hypothetical protein 528174 1149877 LA_0534 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710715.1 527584 D 189518 CDS NP_710716.2 294827668 1149878 complement(528725..529609) 1 NC_004342.2 hypothetical protein 529609 1149878 LA_0535 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710716.2 528725 R 189518 CDS NP_710717.1 24213236 1149879 529726..530745 1 NC_004342.2 hypothetical protein 530745 1149879 LA_0536 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710717.1 529726 D 189518 CDS NP_710718.1 24213237 1149880 complement(531358..532047) 1 NC_004342.2 hydrolase 532047 1149880 LA_0537 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_710718.1 531358 R 189518 CDS NP_710719.1 24213238 1149881 532147..532851 1 NC_004342.2 transcriptional regulator 532851 1149881 LA_0538 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710719.1 532147 D 189518 CDS NP_710721.1 24213240 1149883 complement(533976..534407) 1 NC_004342.2 hypothetical protein 534407 1149883 LA_0540 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710721.1 533976 R 189518 CDS NP_710722.1 24213241 1149884 complement(534512..534880) 1 NC_004342.2 hypothetical protein 534880 1149884 LA_0541 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710722.1 534512 R 189518 CDS NP_710724.1 24213243 1149886 complement(535187..536509) 1 NC_004342.2 hypothetical protein 536509 1149886 LA_0543 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710724.1 535187 R 189518 CDS NP_710725.1 24213244 1149887 complement(536978..538153) 1 NC_004342.2 hypothetical protein 538153 1149887 LA_0544 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710725.1 536978 R 189518 CDS NP_710727.1 24213246 1149889 538278..540803 1 NC_004342.2 hypothetical protein 540803 1149889 LA_0546 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710727.1 538278 D 189518 CDS NP_710728.1 24213247 1149890 complement(541361..542047) 1 NC_004342.2 hypothetical protein 542047 1149890 LA_0547 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710728.1 541361 R 189518 CDS NP_710729.2 294827669 1149891 542282..542671 1 NC_004342.2 hypothetical protein 542671 1149891 LA_0548 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710729.2 542282 D 189518 CDS NP_710730.1 24213249 1149892 542671..543198 1 NC_004342.2 hypothetical protein 543198 1149892 LA_0549 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710730.1 542671 D 189518 CDS NP_710731.2 294827670 1149893 544922..548173 1 NC_004342.2 cation/multidrug efflux pump 548173 acrB 1149893 acrB Leptospira interrogans serovar Lai str. 56601 cation/multidrug efflux pump NP_710731.2 544922 D 189518 CDS NP_710732.1 24213251 1149894 549232..549795 1 NC_004342.2 phosphoribosyl-AMP cyclohydrolase protein 549795 hisI 1149894 hisI Leptospira interrogans serovar Lai str. 56601 phosphoribosyl-AMP cyclohydrolase protein NP_710732.1 549232 D 189518 CDS NP_710733.1 24213252 1149895 549844..550860 1 NC_004342.2 periplasmic solute-binding protein 550860 1149895 LA_0552 Leptospira interrogans serovar Lai str. 56601 periplasmic solute-binding protein NP_710733.1 549844 D 189518 CDS NP_710735.1 24213254 1149897 552036..552293 1 NC_004342.2 hypothetical protein 552293 1149897 LA_0554 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710735.1 552036 D 189518 CDS NP_710737.1 24213256 1149899 complement(552764..553327) 1 NC_004342.2 hypothetical protein 553327 1149899 LA_0556 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710737.1 552764 R 189518 CDS NP_710738.1 24213257 1149900 complement(553396..555786) 1 NC_004342.2 hypothetical protein 555786 1149900 LA_0557 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710738.1 553396 R 189518 CDS NP_710739.1 24213258 1149901 556271..557023 1 NC_004342.2 hypothetical protein 557023 1149901 LA_0558 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710739.1 556271 D 189518 CDS NP_710740.2 294827671 1149902 complement(557244..558317) 1 NC_004342.2 ankyrin-like protein 558317 1149902 LA_0559 Leptospira interrogans serovar Lai str. 56601 ankyrin-like protein NP_710740.2 557244 R 189518 CDS NP_710741.1 24213260 1149903 558652..560325 1 NC_004342.2 acyl-CoA dehydrogenase 560325 caiA 1149903 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_710741.1 558652 D 189518 CDS YP_003573290.1 294827672 9006876 560460..560858 1 NC_004342.2 hypothetical protein 560858 9006876 LA_0560a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573290.1 560460 D 189518 CDS NP_710742.2 294827673 1149904 561352..562521 1 NC_004342.2 ISlin1 transposase 562521 1149904 LA_0561 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710742.2 561352 D 189518 CDS NP_710743.1 24213262 1149905 562807..563289 1 NC_004342.2 hypothetical protein 563289 1149905 LA_0562 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710743.1 562807 D 189518 CDS NP_710744.1 24213263 1149906 complement(563475..564863) 1 NC_004342.2 hypothetical protein 564863 1149906 LA_0563 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710744.1 563475 R 189518 CDS NP_710745.1 24213264 1149907 565110..565616 1 NC_004342.2 hypothetical protein 565616 1149907 LA_0564 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710745.1 565110 D 189518 CDS NP_710746.2 294827674 1149908 complement(565989..567173) 1 NC_004342.2 guanylate cyclase 567173 cyaA 1149908 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_710746.2 565989 R 189518 CDS NP_710747.1 24213266 1149909 568022..569611 1 NC_004342.2 short-chain dehydrogenase 569611 1149909 LA_0566 Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_710747.1 568022 D 189518 CDS NP_710749.1 24213268 1149911 complement(570600..572021) 1 NC_004342.2 fatty acid transport protein 572021 1149911 LA_0568 Leptospira interrogans serovar Lai str. 56601 fatty acid transport protein NP_710749.1 570600 R 189518 CDS NP_710750.2 294827675 1149912 572302..574518 1 NC_004342.2 hypothetical protein 574518 1149912 LA_0569 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710750.2 572302 D 189518 CDS NP_710751.2 294827676 1149913 574588..575427 1 NC_004342.2 hypothetical protein 575427 1149913 LA_0570 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710751.2 574588 D 189518 CDS NP_710752.1 24213271 1149914 575434..576642 1 NC_004342.2 hypothetical protein 576642 1149914 LA_0571 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710752.1 575434 D 189518 CDS NP_710753.2 294827677 1149915 576667..579180 1 NC_004342.2 TonB-dependent outer membrane receptor 579180 1149915 LA_0572 Leptospira interrogans serovar Lai str. 56601 TonB-dependent outer membrane receptor NP_710753.2 576667 D 189518 CDS NP_710754.2 294827678 1149916 579308..579640 1 NC_004342.2 hypothetical protein 579640 1149916 LA_0573 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710754.2 579308 D 189518 CDS NP_710755.1 24213274 1149917 579893..580537 1 NC_004342.2 cytoplasmic membrane protein 580537 dedA 1149917 dedA Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_710755.1 579893 D 189518 CDS NP_710756.1 24213275 1149918 580578..581585 1 NC_004342.2 hypothetical protein 581585 1149918 LA_0575 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710756.1 580578 D 189518 CDS NP_710757.1 24213276 1149919 complement(581860..582999) 1 NC_004342.2 hypothetical protein 582999 1149919 LA_0576 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710757.1 581860 R 189518 CDS NP_710759.2 294827679 1149921 583803..584171 1 NC_004342.2 hypothetical protein 584171 1149921 LA_0578 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710759.2 583803 D 189518 CDS NP_710760.2 294827680 1149922 584213..586438 1 NC_004342.2 bifunctional permease/carbonic anhydrase 586438 sul1 1149922 sul1 Leptospira interrogans serovar Lai str. 56601 bifunctional permease/carbonic anhydrase NP_710760.2 584213 D 189518 CDS NP_710761.2 294827681 1149923 587074..587412 1 NC_004342.2 hypothetical protein 587412 1149923 LA_0580 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710761.2 587074 D 189518 CDS NP_710763.1 24213282 1149925 587536..588915 1 NC_004342.2 outer membrane protein TolC 588915 1149925 LA_0581 Leptospira interrogans serovar Lai str. 56601 outer membrane protein TolC NP_710763.1 587536 D 189518 CDS NP_710764.1 24213283 1149926 588881..591997 1 NC_004342.2 heavy metal efflux pump 591997 1149926 LA_0583 Leptospira interrogans serovar Lai str. 56601 heavy metal efflux pump NP_710764.1 588881 D 189518 CDS NP_710766.2 294827682 1149928 592807..593976 1 NC_004342.2 ISlin1 transposase 593976 1149928 LA_0585 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710766.2 592807 D 189518 CDS NP_710768.1 24213287 1149930 complement(594468..595388) 1 NC_004342.2 lipase 595388 1149930 LA_0587 Leptospira interrogans serovar Lai str. 56601 lipase NP_710768.1 594468 R 189518 CDS NP_710769.2 294827683 1149931 596900..597145 1 NC_004342.2 hypothetical protein 597145 1149931 LA_0588 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710769.2 596900 D 189518 CDS NP_710770.1 24213289 1149932 597327..599225 1 NC_004342.2 hypothetical protein 599225 1149932 LA_0589 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710770.1 597327 D 189518 CDS NP_710771.2 294827684 1149933 599448..599579 1 NC_004342.2 hypothetical protein 599579 1149933 LA_0590 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710771.2 599448 D 189518 CDS NP_710772.1 24213291 1149934 599890..600831 1 NC_004342.2 hypothetical protein 600831 1149934 LA_0591 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710772.1 599890 D 189518 CDS NP_710773.1 24213292 1149935 601204..601497 1 NC_004342.2 hypothetical protein 601497 1149935 LA_0592 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710773.1 601204 D 189518 CDS NP_710774.1 24213293 1149936 601515..601715 1 NC_004342.2 copper chaperone-like protein 601715 copZ 1149936 copZ Leptospira interrogans serovar Lai str. 56601 copper chaperone-like protein NP_710774.1 601515 D 189518 CDS NP_710775.1 24213294 1149937 601712..603931 1 NC_004342.2 cation transport ATPase 603931 zntA 1149937 zntA Leptospira interrogans serovar Lai str. 56601 cation transport ATPase NP_710775.1 601712 D 189518 CDS NP_710776.1 24213295 1149938 complement(604627..605253) 1 NC_004342.2 glutathione S-transferase-like protein 605253 1149938 LA_0595 Leptospira interrogans serovar Lai str. 56601 glutathione S-transferase-like protein NP_710776.1 604627 R 189518 CDS NP_710779.2 294827685 1149941 complement(606147..606587) 1 NC_004342.2 transcriptional regulator 606587 1149941 LA_0598 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_710779.2 606147 R 189518 CDS NP_710780.1 24213299 1149942 606846..607571 1 NC_004342.2 signal transduction protein 607571 1149942 LA_0599 Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_710780.1 606846 D 189518 CDS NP_710781.1 24213300 1149943 complement(607631..608224) 1 NC_004342.2 peptide methionine sulfoxide reductase 608224 msrA 1149943 msrA Leptospira interrogans serovar Lai str. 56601 peptide methionine sulfoxide reductase NP_710781.1 607631 R 189518 CDS NP_710783.1 24213302 1149945 608958..610214 1 NC_004342.2 NAD/FAD-binding protein 610214 1149945 LA_0602 Leptospira interrogans serovar Lai str. 56601 NAD/FAD-binding protein NP_710783.1 608958 D 189518 CDS NP_710784.1 24213303 1149946 complement(610211..611044) 1 NC_004342.2 SAM-dependent methyltransferase 611044 1149946 LA_0603 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_710784.1 610211 R 189518 CDS NP_710786.2 294827686 1149948 611900..612430 1 NC_004342.2 SET family protein 612430 1149948 LA_0605 Leptospira interrogans serovar Lai str. 56601 SET family protein NP_710786.2 611900 D 189518 CDS NP_710787.2 294827687 1149949 complement(612448..613047) 1 NC_004342.2 hypothetical protein 613047 1149949 LA_0606 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710787.2 612448 R 189518 CDS NP_710788.1 24213307 1149950 complement(613106..613906) 1 NC_004342.2 MCE-like protein 613906 1149950 LA_0607 Leptospira interrogans serovar Lai str. 56601 MCE-like protein NP_710788.1 613106 R 189518 CDS NP_710789.2 294827688 1149951 complement(614160..614354) 1 NC_004342.2 hypothetical protein 614354 1149951 LA_0609 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710789.2 614160 R 189518 CDS NP_710791.1 24213310 1149953 614590..615339 1 NC_004342.2 hypothetical protein 615339 1149953 LA_0610 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710791.1 614590 D 189518 CDS NP_710792.1 24213311 1149954 615341..616570 1 NC_004342.2 cell division protein FtsA 616570 ftsA 1149954 ftsA Leptospira interrogans serovar Lai str. 56601 cell division protein FtsA NP_710792.1 615341 D 189518 CDS NP_710793.1 24213312 1149955 616589..617791 1 NC_004342.2 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 617791 ftsZ 1149955 ftsZ Leptospira interrogans serovar Lai str. 56601 cell division protein FtsZ NP_710793.1 616589 D 189518 CDS NP_710796.2 294827689 1149958 complement(619408..619740) 1 NC_004342.2 hypothetical protein 619740 1149958 LA_0615 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710796.2 619408 R 189518 CDS NP_710797.2 294827690 1149959 complement(619769..620836) 1 NC_004342.2 hypothetical protein 620836 lipL41 1149959 lipL41 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710797.2 619769 R 189518 CDS NP_710798.2 294827691 1149960 621008..621520 1 NC_004342.2 hypothetical protein 621520 1149960 LA_0617 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710798.2 621008 D 189518 CDS NP_710799.2 294827692 1149961 621517..622491 1 NC_004342.2 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 622491 nadA 1149961 nadA Leptospira interrogans serovar Lai str. 56601 quinolinate synthetase NP_710799.2 621517 D 189518 CDS NP_710801.1 24213320 1149963 complement(623743..625656) 1 NC_004342.2 hypothetical protein 625656 1149963 LA_0620 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710801.1 623743 R 189518 CDS NP_710806.1 24213325 1149968 628058..629953 1 NC_004342.2 ATP-dependent DNA helicase RecQ 629953 recQ 1149968 recQ Leptospira interrogans serovar Lai str. 56601 ATP-dependent DNA helicase RecQ NP_710806.1 628058 D 189518 CDS NP_710808.2 294827693 1149970 631268..632731 1 NC_004342.2 glycosyltransferase 632731 1149970 LA_0627 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_710808.2 631268 D 189518 CDS NP_710810.1 24213329 1149972 633754..634035 1 NC_004342.2 hypothetical protein 634035 1149972 LA_0629 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710810.1 633754 D 189518 CDS NP_710811.2 294827694 1149973 634042..635202 1 NC_004342.2 oxidoreductase-like protein 635202 1149973 LA_0630 Leptospira interrogans serovar Lai str. 56601 oxidoreductase-like protein NP_710811.2 634042 D 189518 CDS NP_710812.1 24213331 1149974 635195..636079 1 NC_004342.2 hypothetical protein 636079 1149974 LA_0631 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710812.1 635195 D 189518 CDS NP_710813.2 294827695 1149975 636165..636641 1 NC_004342.2 phosphoenolpyruvate-dependent enzyme IIA component of the PTS system 636641 ptsN 1149975 ptsN Leptospira interrogans serovar Lai str. 56601 phosphoenolpyruvate-dependent enzyme IIA component of the PTS system NP_710813.2 636165 D 189518 CDS NP_710814.1 24213333 1149976 636644..637537 1 NC_004342.2 oligopeptide ABC transporter permease 637537 dppB 1149976 dppB Leptospira interrogans serovar Lai str. 56601 oligopeptide ABC transporter permease NP_710814.1 636644 D 189518 CDS NP_710815.1 24213334 1149977 637534..638295 1 NC_004342.2 dipeptide/oligopeptide ABC transporter permease 638295 dppC 1149977 dppC Leptospira interrogans serovar Lai str. 56601 dipeptide/oligopeptide ABC transporter permease NP_710815.1 637534 D 189518 CDS NP_710816.1 24213335 1149978 638292..639875 1 NC_004342.2 S-layer-like protein 639875 1149978 LA_0635 Leptospira interrogans serovar Lai str. 56601 S-layer-like protein NP_710816.1 638292 D 189518 CDS NP_710817.2 294827696 1149979 complement(640866..642035) 1 NC_004342.2 ISlin1 transposase 642035 1149979 LA_0636 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710817.2 640866 R 189518 CDS NP_710818.1 24213337 1149980 complement(643585..644877) 1 NC_004342.2 dihydrofolate synthase 644877 folC 1149980 folC Leptospira interrogans serovar Lai str. 56601 dihydrofolate synthase NP_710818.1 643585 R 189518 CDS NP_710819.1 24213338 1149981 complement(644874..645815) 1 NC_004342.2 shikimate 5-dehydrogenase 645815 aroE 1149981 aroE Leptospira interrogans serovar Lai str. 56601 shikimate 5-dehydrogenase NP_710819.1 644874 R 189518 CDS NP_710820.2 294827697 1149982 645932..646324 1 NC_004342.2 hypothetical protein 646324 1149982 LA_0639 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710820.2 645932 D 189518 CDS NP_710821.1 24213340 1149983 647071..647736 1 NC_004342.2 hypothetical protein 647736 1149983 LA_0640 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710821.1 647071 D 189518 CDS NP_710822.1 24213341 1149984 647733..647897 1 NC_004342.2 hypothetical protein 647897 1149984 LA_0641 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710822.1 647733 D 189518 CDS NP_710824.1 24213343 1149986 complement(648515..649276) 1 NC_004342.2 glycosyltransferase 649276 1149986 LA_0643 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_710824.1 648515 R 189518 CDS NP_710825.2 294827698 1149987 complement(649277..649972) 1 NC_004342.2 hypothetical protein 649972 1149987 LA_0645 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710825.2 649277 R 189518 CDS NP_710826.2 294827699 1149988 650013..651413 1 NC_004342.2 hypothetical protein 651413 1149988 LA_0644 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710826.2 650013 D 189518 CDS NP_710827.1 24213346 1149989 651410..652564 1 NC_004342.2 30S ribosomal protein S1 652564 rpsA 1149989 rpsA Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S1 NP_710827.1 651410 D 189518 CDS NP_710828.1 24213347 1149990 652569..653030 1 NC_004342.2 rRNA methylase 653030 cspR 1149990 cspR Leptospira interrogans serovar Lai str. 56601 rRNA methylase NP_710828.1 652569 D 189518 CDS NP_710829.1 24213348 1149991 653076..653744 1 NC_004342.2 anti-sigma regulatory factor 653744 1149991 LA_0648 Leptospira interrogans serovar Lai str. 56601 anti-sigma regulatory factor NP_710829.1 653076 D 189518 CDS NP_710830.1 24213349 1149992 653751..655751 1 NC_004342.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 655751 uvrB 1149992 uvrB Leptospira interrogans serovar Lai str. 56601 excinuclease ABC subunit B NP_710830.1 653751 D 189518 CDS NP_710831.2 294827700 1149993 655769..656362 1 NC_004342.2 intramembrane serine protease 656362 glpG 1149993 glpG Leptospira interrogans serovar Lai str. 56601 intramembrane serine protease NP_710831.2 655769 D 189518 CDS YP_003573291.1 294827701 9006877 657102..657458 1 NC_004342.2 hypothetical protein 657458 9006877 LA_0650a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573291.1 657102 D 189518 CDS NP_710834.2 294827702 1149996 complement(657881..658213) 1 NC_004342.2 anti-sigma factor antagonist 658213 1149996 LA_0653 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_710834.2 657881 R 189518 CDS NP_710835.2 294827703 1149997 658336..659034 1 NC_004342.2 hypothetical protein 659034 1149997 LA_0654 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710835.2 658336 D 189518 CDS NP_710836.1 24213355 1149998 659044..659769 1 NC_004342.2 DnaJ-like protein 659769 1149998 LA_0655 Leptospira interrogans serovar Lai str. 56601 DnaJ-like protein NP_710836.1 659044 D 189518 CDS NP_710837.1 24213356 1149999 659775..660767 1 NC_004342.2 mannose-6-phosphate isomerase 660767 manA 1149999 manA Leptospira interrogans serovar Lai str. 56601 mannose-6-phosphate isomerase NP_710837.1 659775 D 189518 CDS NP_710838.1 24213357 1150000 660777..661064 1 NC_004342.2 HNH family endonuclease 661064 mcrA 1150000 mcrA Leptospira interrogans serovar Lai str. 56601 HNH family endonuclease NP_710838.1 660777 D 189518 CDS NP_710840.1 24213359 1150002 662087..662422 1 NC_004342.2 hypothetical protein 662422 1150002 LA_0659 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710840.1 662087 D 189518 CDS NP_710843.2 294827704 1150005 complement(663171..663905) 1 NC_004342.2 endoflagellar motor protein A 663905 motA 1150005 motA Leptospira interrogans serovar Lai str. 56601 endoflagellar motor protein A NP_710843.2 663171 R 189518 CDS NP_710844.2 294827705 1150006 665357..666667 1 NC_004342.2 hypothetical protein 666667 1150006 LA_0663 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710844.2 665357 D 189518 CDS NP_710846.1 24213365 1150008 667502..668467 1 NC_004342.2 metallo-beta-lactamase superfamily protein 668467 1150008 LA_0665 Leptospira interrogans serovar Lai str. 56601 metallo-beta-lactamase superfamily protein NP_710846.1 667502 D 189518 CDS NP_710847.1 24213366 1150009 668545..669567 1 NC_004342.2 cytochrome c peroxidase 669567 mauG 1150009 mauG Leptospira interrogans serovar Lai str. 56601 cytochrome c peroxidase NP_710847.1 668545 D 189518 CDS NP_710851.2 294827706 1150013 complement(671274..671885) 1 NC_004342.2 hypothetical protein 671885 1150013 LA_0670 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710851.2 671274 R 189518 CDS NP_710852.1 24213371 1150014 complement(672016..673296) 1 NC_004342.2 citrate synthase 673296 gltA 1150014 gltA Leptospira interrogans serovar Lai str. 56601 citrate synthase NP_710852.1 672016 R 189518 CDS NP_710854.2 294827707 1150016 complement(674635..676233) 1 NC_004342.2 CMP-KDO synthetase-like protein 676233 spsF 1150016 spsF Leptospira interrogans serovar Lai str. 56601 CMP-KDO synthetase-like protein NP_710854.2 674635 R 189518 CDS NP_710855.1 24213374 1150017 complement(676208..677752) 1 NC_004342.2 oxidoreductase 677752 1150017 LA_0674 Leptospira interrogans serovar Lai str. 56601 oxidoreductase NP_710855.1 676208 R 189518 CDS NP_710856.2 294827708 1150018 complement(677802..678836) 1 NC_004342.2 hypothetical protein 678836 1150018 LA_0675 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710856.2 677802 R 189518 CDS NP_710857.2 294827709 1150019 complement(679078..681153) 1 NC_004342.2 methyl-accepting chemotaxis protein 681153 1150019 LA_0676 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_710857.2 679078 R 189518 CDS NP_710859.1 24213378 1150021 complement(682072..684150) 1 NC_004342.2 methyl-accepting chemotaxis protein 684150 1150021 LA_0678 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_710859.1 682072 R 189518 CDS YP_003573292.1 294827710 9006879 complement(684388..684576) 1 NC_004342.2 hypothetical protein 684576 9006879 LA_0678a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573292.1 684388 R 189518 CDS NP_710861.2 294827711 1150023 684728..685087 1 NC_004342.2 hypothetical protein 685087 1150023 LA_0680 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710861.2 684728 D 189518 CDS NP_710863.1 24213382 1150025 complement(685983..686189) 1 NC_004342.2 hypothetical protein 686189 1150025 LA_0682 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710863.1 685983 R 189518 CDS NP_710865.1 24213384 1150027 complement(686707..687471) 1 NC_004342.2 CRISPR-associated protein Cas1 687471 1150027 LA_0684 Leptospira interrogans serovar Lai str. 56601 CRISPR-associated protein Cas1 NP_710865.1 686707 R 189518 CDS NP_710866.1 24213385 1150028 complement(687725..687997) 1 NC_004342.2 RecB-like exonuclease 687997 1150028 LA_0685 Leptospira interrogans serovar Lai str. 56601 RecB-like exonuclease NP_710866.1 687725 R 189518 CDS NP_710867.1 24213386 1150029 complement(688297..689217) 1 NC_004342.2 hypothetical protein 689217 1150029 LA_0686 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710867.1 688297 R 189518 CDS NP_710868.1 24213387 1150030 complement(689220..690935) 1 NC_004342.2 hypothetical protein 690935 1150030 LA_0687 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710868.1 689220 R 189518 CDS NP_710869.1 24213388 1150031 complement(690932..691636) 1 NC_004342.2 CRISPR-associated CT1134 family protein 691636 1150031 LA_0688 Leptospira interrogans serovar Lai str. 56601 CRISPR-associated CT1134 family protein NP_710869.1 690932 R 189518 CDS NP_710870.1 24213389 1150032 complement(691636..692739) 1 NC_004342.2 hypothetical protein 692739 1150032 LA_0689 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710870.1 691636 R 189518 CDS NP_710871.1 24213390 1150033 complement(692740..693873) 1 NC_004342.2 helicase 693873 1150033 LA_0690 Leptospira interrogans serovar Lai str. 56601 helicase NP_710871.1 692740 R 189518 CDS NP_710874.1 24213393 1150036 complement(696371..697588) 1 NC_004342.2 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 697588 lysC 1150036 lysC Leptospira interrogans serovar Lai str. 56601 aspartate kinase NP_710874.1 696371 R 189518 CDS NP_710875.1 24213394 1150037 697769..699574 1 NC_004342.2 sodium/glucose cotransport protein 699574 1150037 LA_0694 Leptospira interrogans serovar Lai str. 56601 sodium/glucose cotransport protein NP_710875.1 697769 D 189518 CDS NP_710876.1 24213395 1150038 700980..701702 1 NC_004342.2 hypothetical protein 701702 1150038 LA_0695 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710876.1 700980 D 189518 CDS NP_710877.1 24213396 1150039 complement(701770..703704) 1 NC_004342.2 hypothetical protein 703704 1150039 LA_0696 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710877.1 701770 R 189518 CDS NP_710878.1 24213397 1150040 complement(703712..704836) 1 NC_004342.2 von Willebrand factor A 704836 1150040 LA_0697 Leptospira interrogans serovar Lai str. 56601 von Willebrand factor A NP_710878.1 703712 R 189518 CDS NP_710880.1 24213399 1150042 complement(704989..707286) 1 NC_004342.2 hypothetical protein 707286 1150042 LA_0699 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710880.1 704989 R 189518 CDS NP_710881.1 24213400 1150043 complement(707484..708596) 1 NC_004342.2 MoxR-like ATPase 708596 1150043 LA_0700 Leptospira interrogans serovar Lai str. 56601 MoxR-like ATPase NP_710881.1 707484 R 189518 CDS NP_710882.1 24213401 1150044 complement(709003..711828) 1 NC_004342.2 molybdate metabolism regulator 711828 1150044 LA_0701 Leptospira interrogans serovar Lai str. 56601 molybdate metabolism regulator NP_710882.1 709003 R 189518 CDS NP_710883.2 294827712 1150045 711983..713152 1 NC_004342.2 ISlin1 transposase 713152 1150045 LA_0702 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710883.2 711983 D 189518 CDS NP_710884.1 24213403 1150046 complement(713145..715214) 1 NC_004342.2 molybdate metabolism regulator 715214 1150046 LA_0703 Leptospira interrogans serovar Lai str. 56601 molybdate metabolism regulator NP_710884.1 713145 R 189518 CDS NP_710886.2 294827713 1150048 715920..716330 1 NC_004342.2 cytoplasmic membrane protein 716330 1150048 LA_0705 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_710886.2 715920 D 189518 CDS NP_710887.1 24213406 1150049 717511..720423 1 NC_004342.2 hypothetical protein 720423 1150049 LA_0706 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710887.1 717511 D 189518 CDS NP_710888.1 24213407 1150050 complement(720638..721552) 1 NC_004342.2 transposase 721552 1150050 LA_0707 Leptospira interrogans serovar Lai str. 56601 transposase NP_710888.1 720638 R 189518 CDS NP_710890.2 294827714 1150052 722875..732141 1 NC_004342.2 hypothetical protein 732141 1150052 LA_0709 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710890.2 722875 D 189518 CDS NP_710891.1 24213410 1150053 732154..732822 1 NC_004342.2 hypothetical protein 732822 1150053 LA_0710 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710891.1 732154 D 189518 CDS NP_710892.2 294827715 1150054 733046..734029 1 NC_004342.2 hypothetical protein 734029 1150054 LA_0711 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710892.2 733046 D 189518 CDS NP_710893.2 294827716 1150055 734022..734654 1 NC_004342.2 hypothetical protein 734654 1150055 LA_0712 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710893.2 734022 D 189518 CDS NP_710894.2 294827717 1150056 734860..737532 1 NC_004342.2 hypothetical protein 737532 1150056 LA_0713 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710894.2 734860 D 189518 CDS NP_710895.1 24213414 1150057 737484..738308 1 NC_004342.2 hypothetical protein 738308 1150057 LA_0714 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710895.1 737484 D 189518 CDS NP_710896.1 24213415 1150058 738514..739080 1 NC_004342.2 hypothetical protein 739080 1150058 LA_0715 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710896.1 738514 D 189518 CDS NP_710897.2 294827718 1150059 complement(739484..739801) 1 NC_004342.2 transposase 739801 1150059 LA_0716 Leptospira interrogans serovar Lai str. 56601 transposase NP_710897.2 739484 R 189518 CDS NP_710898.1 24213417 1150060 complement(739947..740240) 1 NC_004342.2 IS3 transposase 740240 1150060 LA_0717 Leptospira interrogans serovar Lai str. 56601 IS3 transposase NP_710898.1 739947 R 189518 CDS NP_710899.1 24213418 1150061 740313..740867 1 NC_004342.2 hypothetical protein 740867 1150061 LA_0718 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710899.1 740313 D 189518 CDS NP_710900.1 24213419 1150062 complement(741408..742166) 1 NC_004342.2 hypothetical protein 742166 1150062 LA_0719 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710900.1 741408 R 189518 CDS NP_710901.1 24213420 1150063 742207..742956 1 NC_004342.2 hypothetical protein 742956 1150063 LA_0720 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710901.1 742207 D 189518 CDS NP_710904.2 294827719 1150066 743974..744489 1 NC_004342.2 Holliday junction endodeoxyribonuclease protein 744489 ruvC 1150066 ruvC Leptospira interrogans serovar Lai str. 56601 Holliday junction endodeoxyribonuclease protein NP_710904.2 743974 D 189518 CDS NP_710907.1 24213426 1150069 746137..748701 1 NC_004342.2 sulfatase 748701 1150069 LA_0726 Leptospira interrogans serovar Lai str. 56601 sulfatase NP_710907.1 746137 D 189518 CDS NP_710908.1 24213427 1150070 748828..752148 1 NC_004342.2 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 752148 carB 1150070 carB Leptospira interrogans serovar Lai str. 56601 carbamoyl phosphate synthase large subunit NP_710908.1 748828 D 189518 CDS YP_003573293.1 294827720 9006880 complement(752294..752482) 1 NC_004342.2 hypothetical protein 752482 9006880 LA_0727a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573293.1 752294 R 189518 CDS YP_003573294.1 294827721 9006881 complement(752445..752744) 1 NC_004342.2 hypothetical protein 752744 9006881 LA_0727b Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573294.1 752445 R 189518 CDS NP_710909.2 294827722 1150071 753237..753764 1 NC_004342.2 hypothetical protein 753764 1150071 LA_0728 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710909.2 753237 D 189518 CDS YP_003573295.1 294827723 9006882 complement(753835..753966) 1 NC_004342.2 hypothetical protein 753966 9006882 LA_0728a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573295.1 753835 R 189518 CDS NP_710911.2 294827724 1150073 754541..755386 1 NC_004342.2 hypothetical protein 755386 1150073 LA_0730 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710911.2 754541 D 189518 CDS NP_710912.2 294827725 1150074 complement(755920..756138) 1 NC_004342.2 hypothetical protein 756138 1150074 LA_0732 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710912.2 755920 R 189518 CDS NP_710915.1 24213434 1150077 756556..757107 1 NC_004342.2 peroxiredoxin-like protein 757107 1150077 LA_0734 Leptospira interrogans serovar Lai str. 56601 peroxiredoxin-like protein NP_710915.1 756556 D 189518 CDS NP_710916.1 24213435 1150078 757112..758338 1 NC_004342.2 hypothetical protein 758338 1150078 LA_0735 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710916.1 757112 D 189518 CDS NP_710917.1 24213436 1150079 759001..760866 1 NC_004342.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 760866 1150079 LA_0736 Leptospira interrogans serovar Lai str. 56601 elongation factor G NP_710917.1 759001 D 189518 CDS NP_710918.1 24213437 1150080 760917..762122 1 NC_004342.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 762122 tufB 1150080 tufB Leptospira interrogans serovar Lai str. 56601 elongation factor Tu NP_710918.1 760917 D 189518 CDS NP_710919.1 24213438 1150081 762137..762445 1 NC_004342.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 762445 rpsJ 1150081 rpsJ Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S10 NP_710919.1 762137 D 189518 CDS NP_710920.1 24213439 1150082 762457..763077 1 NC_004342.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 763077 rplC 1150082 rplC Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L3 NP_710920.1 762457 D 189518 CDS NP_710921.1 24213440 1150083 763095..763730 1 NC_004342.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 763730 rplD 1150083 rplD Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L4 NP_710921.1 763095 D 189518 CDS NP_710922.1 24213441 1150084 763727..764041 1 NC_004342.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 764041 rplW 1150084 rplW Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L23 NP_710922.1 763727 D 189518 CDS NP_710923.1 24213442 1150085 764045..764884 1 NC_004342.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 764884 rplB 1150085 rplB Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L2 NP_710923.1 764045 D 189518 CDS NP_710924.1 24213443 1150086 764893..765174 1 NC_004342.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 765174 rpsS 1150086 rpsS Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S19 NP_710924.1 764893 D 189518 CDS NP_710925.1 24213444 1150087 765174..765506 1 NC_004342.2 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 765506 rplV 1150087 rplV Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L22 NP_710925.1 765174 D 189518 CDS NP_710926.1 24213445 1150088 765519..766196 1 NC_004342.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 766196 rpsC 1150088 rpsC Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S3 NP_710926.1 765519 D 189518 CDS NP_710927.1 24213446 1150089 766219..766632 1 NC_004342.2 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 766632 rplP 1150089 rplP Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L16 NP_710927.1 766219 D 189518 CDS NP_710928.1 24213447 1150090 766629..766913 1 NC_004342.2 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 766913 1150090 LA_0747 Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L29 NP_710928.1 766629 D 189518 CDS NP_710929.2 294827726 1150091 766989..767192 1 NC_004342.2 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 767192 rpsQ 1150091 rpsQ Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S17 NP_710929.2 766989 D 189518 CDS NP_710930.1 24213449 1150092 767194..767586 1 NC_004342.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 767586 rplN 1150092 rplN Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L14 NP_710930.1 767194 D 189518 CDS NP_710931.1 24213450 1150093 767586..767945 1 NC_004342.2 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 767945 rplX 1150093 rplX Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L24 NP_710931.1 767586 D 189518 CDS NP_710932.1 24213451 1150094 767949..768497 1 NC_004342.2 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 768497 rplE 1150094 rplE Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L5 NP_710932.1 767949 D 189518 CDS NP_710933.1 24213452 1150095 768517..768702 1 NC_004342.2 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 768702 rpsN 1150095 rpsN Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S14 NP_710933.1 768517 D 189518 CDS NP_710934.1 24213453 1150096 768722..769123 1 NC_004342.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 769123 rpsH 1150096 rpsH Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S8 NP_710934.1 768722 D 189518 CDS NP_710935.1 24213454 1150097 769150..769689 1 NC_004342.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 769689 rplF 1150097 rplF Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L6 NP_710935.1 769150 D 189518 CDS NP_710936.1 24213455 1150098 769693..770061 1 NC_004342.2 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 770061 rplR 1150098 rplR Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L18 NP_710936.1 769693 D 189518 CDS NP_710937.2 294827727 1150099 770063..770569 1 NC_004342.2 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 770569 rpsE 1150099 rpsE Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S5 NP_710937.2 770063 D 189518 CDS NP_710938.1 24213457 1150100 770582..770761 1 NC_004342.2 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 770761 rpmD 1150100 rpmD Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L30 NP_710938.1 770582 D 189518 CDS NP_710939.1 24213458 1150101 770777..771319 1 NC_004342.2 late assembly protein; 50S ribosomal protein L15 771319 rplO 1150101 rplO Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L15 NP_710939.1 770777 D 189518 CDS NP_710940.1 24213459 1150102 771334..772716 1 NC_004342.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 772716 secY 1150102 secY Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit SecY NP_710940.1 771334 D 189518 CDS NP_710941.1 24213460 1150103 772724..773287 1 NC_004342.2 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 773287 adk 1150103 adk Leptospira interrogans serovar Lai str. 56601 adenylate kinase NP_710941.1 772724 D 189518 CDS NP_710942.1 24213461 1150104 773290..773508 1 NC_004342.2 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 773508 infA 1150104 infA Leptospira interrogans serovar Lai str. 56601 translation initiation factor IF-1 NP_710942.1 773290 D 189518 CDS YP_003573296.1 294827728 9006883 773517..773630 1 NC_004342.2 50S ribosomal protein L36 773630 rpmJ 9006883 rpmJ Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L36 YP_003573296.1 773517 D 189518 CDS NP_710943.1 24213462 1150105 773634..774011 1 NC_004342.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 774011 rpsM 1150105 rpsM Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S13 NP_710943.1 773634 D 189518 CDS NP_710944.1 24213463 1150106 774014..774424 1 NC_004342.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 774424 rpsK 1150106 rpsK Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S11 NP_710944.1 774014 D 189518 CDS NP_710945.1 24213464 1150107 774436..775059 1 NC_004342.2 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 775059 rpsD 1150107 rpsD Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S4 NP_710945.1 774436 D 189518 CDS NP_710946.1 24213465 1150108 775082..776059 1 NC_004342.2 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 776059 rpoA 1150108 rpoA Leptospira interrogans serovar Lai str. 56601 DNA-directed RNA polymerase subunit alpha NP_710946.1 775082 D 189518 CDS NP_710947.1 24213466 1150109 776061..776576 1 NC_004342.2 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 776576 rplQ 1150109 rplQ Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L17 NP_710947.1 776061 D 189518 CDS NP_710950.2 294827729 1150112 complement(777858..779666) 1 NC_004342.2 hypothetical protein 779666 1150112 LA_0769 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710950.2 777858 R 189518 CDS NP_710954.1 24213473 1150116 complement(781812..782957) 1 NC_004342.2 hypothetical protein 782957 1150116 LA_0773 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710954.1 781812 R 189518 CDS NP_710956.2 294827730 1150118 784079..785248 1 NC_004342.2 ISlin1 transposase 785248 1150118 LA_0775 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_710956.2 784079 D 189518 CDS NP_710957.1 24213476 1150119 complement(786547..787773) 1 NC_004342.2 catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis; L,L-diaminopimelate aminotransferase 787773 1150119 LA_0776 Leptospira interrogans serovar Lai str. 56601 L,L-diaminopimelate aminotransferase NP_710957.1 786547 R 189518 CDS NP_710958.2 294827731 1150120 complement(787757..788122) 1 NC_004342.2 hypothetical protein 788122 1150120 LA_0777 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710958.2 787757 R 189518 CDS NP_710959.1 24213478 1150121 complement(788128..789090) 1 NC_004342.2 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 789090 pyrB 1150121 pyrB Leptospira interrogans serovar Lai str. 56601 aspartate carbamoyltransferase NP_710959.1 788128 R 189518 CDS NP_710960.2 294827732 1150122 complement(789091..790035) 1 NC_004342.2 fatty acid desaturase 790035 1150122 LA_0779 Leptospira interrogans serovar Lai str. 56601 fatty acid desaturase NP_710960.2 789091 R 189518 CDS NP_710962.1 24213481 1150124 complement(790544..790852) 1 NC_004342.2 hypothetical protein 790852 1150124 LA_0781 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710962.1 790544 R 189518 CDS NP_710963.1 24213482 1150125 complement(790913..791233) 1 NC_004342.2 hypothetical protein 791233 1150125 LA_0782 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710963.1 790913 R 189518 CDS NP_710965.1 24213484 1150127 791866..792384 1 NC_004342.2 hypothetical protein 792384 1150127 LA_0784 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710965.1 791866 D 189518 CDS NP_710966.1 24213485 1150128 792785..793828 1 NC_004342.2 Zn-dependent hydrolase 793828 1150128 LA_0785 Leptospira interrogans serovar Lai str. 56601 Zn-dependent hydrolase NP_710966.1 792785 D 189518 CDS NP_710967.1 24213486 1150129 complement(794038..795162) 1 NC_004342.2 arabinose kinase 795162 1150129 LA_0786 Leptospira interrogans serovar Lai str. 56601 arabinose kinase NP_710967.1 794038 R 189518 CDS NP_710968.2 294827733 1150130 complement(795159..795983) 1 NC_004342.2 rRNA methylase 795983 spoU 1150130 spoU Leptospira interrogans serovar Lai str. 56601 rRNA methylase NP_710968.2 795159 R 189518 CDS NP_710969.1 24213488 1150131 complement(795980..796927) 1 NC_004342.2 SAM-dependent methyltransferase 796927 1150131 LA_0788 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_710969.1 795980 R 189518 CDS NP_710970.2 294827734 1150132 complement(796905..798524) 1 NC_004342.2 SAM-dependent methyltransferase 798524 1150132 LA_0789 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_710970.2 796905 R 189518 CDS NP_710971.1 24213490 1150133 complement(798563..799852) 1 NC_004342.2 citrate synthase 799852 gltA 1150133 gltA Leptospira interrogans serovar Lai str. 56601 citrate synthase NP_710971.1 798563 R 189518 CDS NP_710972.1 24213491 1150134 complement(799964..802213) 1 NC_004342.2 transglycosylase 802213 1150134 LA_0791 Leptospira interrogans serovar Lai str. 56601 transglycosylase NP_710972.1 799964 R 189518 CDS NP_710973.1 24213492 1150135 802271..803584 1 NC_004342.2 hypothetical protein 803584 1150135 LA_0792 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710973.1 802271 D 189518 CDS NP_710974.1 24213493 1150136 complement(803912..804445) 1 NC_004342.2 hypothetical protein 804445 1150136 LA_0793 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710974.1 803912 R 189518 CDS NP_710975.1 24213494 1150137 804641..805186 1 NC_004342.2 acetyltransferase-like protein 805186 1150137 LA_0794 Leptospira interrogans serovar Lai str. 56601 acetyltransferase-like protein NP_710975.1 804641 D 189518 CDS NP_710977.2 294827735 1150139 805430..806065 1 NC_004342.2 hypothetical protein 806065 1150139 LA_0795 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710977.2 805430 D 189518 CDS NP_710979.1 24213498 1150141 806855..807622 1 NC_004342.2 hypothetical protein 807622 1150141 LA_0798 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710979.1 806855 D 189518 CDS NP_710980.1 24213499 1150142 807742..808182 1 NC_004342.2 cell shape determination protein 808182 1150142 LA_0799 Leptospira interrogans serovar Lai str. 56601 cell shape determination protein NP_710980.1 807742 D 189518 CDS NP_710981.1 24213500 1150143 808240..809298 1 NC_004342.2 pyridoxal phosphate biosynthesis protein 809298 pdxA 1150143 pdxA Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate biosynthesis protein NP_710981.1 808240 D 189518 CDS NP_710982.1 24213501 1150144 809342..809785 1 NC_004342.2 hypothetical protein 809785 1150144 LA_0801 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710982.1 809342 D 189518 CDS NP_710983.1 24213502 1150145 809804..810304 1 NC_004342.2 TPR-repeat-containing protein 810304 pilF 1150145 pilF Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_710983.1 809804 D 189518 CDS NP_710984.1 24213503 1150146 810965..811351 1 NC_004342.2 hypothetical protein 811351 1150146 LA_0803 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710984.1 810965 D 189518 CDS NP_710985.1 24213504 1150147 complement(811498..812217) 1 NC_004342.2 hypothetical protein 812217 1150147 LA_0804 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710985.1 811498 R 189518 CDS NP_710986.1 24213505 1150148 complement(812322..812441) 1 NC_004342.2 hypothetical protein 812441 1150148 LA_0805 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710986.1 812322 R 189518 CDS NP_710987.2 294827736 1150149 complement(812691..813305) 1 NC_004342.2 thymidylate kinase 813305 tmk 1150149 tmk Leptospira interrogans serovar Lai str. 56601 thymidylate kinase NP_710987.2 812691 R 189518 CDS NP_710989.1 24213508 1150151 813415..814038 1 NC_004342.2 serine protease 814038 1150151 LA_0808 Leptospira interrogans serovar Lai str. 56601 serine protease NP_710989.1 813415 D 189518 CDS NP_710990.1 24213509 1150152 814261..815427 1 NC_004342.2 trypsin-like serine protease 815427 degQ 1150152 degQ Leptospira interrogans serovar Lai str. 56601 trypsin-like serine protease NP_710990.1 814261 D 189518 CDS NP_710991.1 24213510 1150153 815428..816453 1 NC_004342.2 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 816453 ruvB 1150153 ruvB Leptospira interrogans serovar Lai str. 56601 Holliday junction DNA helicase RuvB NP_710991.1 815428 D 189518 CDS NP_710992.1 24213511 1150154 816428..817345 1 NC_004342.2 hypothetical protein 817345 1150154 LA_0811 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710992.1 816428 D 189518 CDS NP_710993.2 294827737 1150155 817360..817695 1 NC_004342.2 hypothetical protein 817695 1150155 LA_0812 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710993.2 817360 D 189518 CDS NP_710994.2 294827738 1150156 817707..818159 1 NC_004342.2 hypothetical protein 818159 1150156 LA_0813 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710994.2 817707 D 189518 CDS NP_710995.1 24213514 1150157 complement(818343..818528) 1 NC_004342.2 hypothetical protein 818528 1150157 LA_0814 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710995.1 818343 R 189518 CDS NP_710996.1 24213515 1150158 complement(818564..820399) 1 NC_004342.2 histidine kinase sensor protein 820399 1150158 LA_0815 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_710996.1 818564 R 189518 CDS NP_710997.1 24213516 1150159 complement(820400..821101) 1 NC_004342.2 response regulator containing a signal receiver domain and a DNA-binding domain 821101 citB 1150159 citB Leptospira interrogans serovar Lai str. 56601 response regulator containing a signal receiver domain and a DNA-binding domain NP_710997.1 820400 R 189518 CDS NP_710998.1 24213517 1150160 complement(821760..822182) 1 NC_004342.2 hypothetical protein 822182 1150160 LA_0817 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710998.1 821760 R 189518 CDS NP_710999.2 294827739 1150161 complement(822206..823210) 1 NC_004342.2 hypothetical protein 823210 1150161 LA_0818 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_710999.2 822206 R 189518 CDS NP_711000.1 24213519 1150162 823309..823509 1 NC_004342.2 hypothetical protein 823509 1150162 LA_0819 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711000.1 823309 D 189518 CDS NP_711001.2 294827740 1150163 823506..824081 1 NC_004342.2 hypothetical protein 824081 1150163 LA_0820 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711001.2 823506 D 189518 CDS NP_711002.1 24213521 1150164 824078..824644 1 NC_004342.2 N-6 adenine-specific DNA methylase 824644 1150164 LA_0821 Leptospira interrogans serovar Lai str. 56601 N-6 adenine-specific DNA methylase NP_711002.1 824078 D 189518 CDS NP_711004.1 24213523 1150166 complement(825367..826278) 1 NC_004342.2 alpha/beta hydrolase 826278 1150166 LA_0823 Leptospira interrogans serovar Lai str. 56601 alpha/beta hydrolase NP_711004.1 825367 R 189518 CDS NP_711005.2 294827741 1150167 complement(826394..826789) 1 NC_004342.2 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 826789 1150167 LA_0824 Leptospira interrogans serovar Lai str. 56601 methionine sulfoxide reductase B NP_711005.2 826394 R 189518 CDS NP_711006.1 24213525 1150168 complement(827007..827621) 1 NC_004342.2 transcriptional regulator 827621 1150168 LA_0825 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711006.1 827007 R 189518 CDS NP_711007.1 24213526 1150169 complement(827602..827802) 1 NC_004342.2 hypothetical protein 827802 1150169 LA_0826 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711007.1 827602 R 189518 CDS NP_711008.1 24213527 1150170 827862..828722 1 NC_004342.2 thioesterase 828722 1150170 LA_0827 Leptospira interrogans serovar Lai str. 56601 thioesterase NP_711008.1 827862 D 189518 CDS NP_711009.1 24213528 1150171 828759..830084 1 NC_004342.2 acetyl-CoA acetyltransferase 830084 paaJ 1150171 paaJ Leptospira interrogans serovar Lai str. 56601 acetyl-CoA acetyltransferase NP_711009.1 828759 D 189518 CDS NP_711010.1 24213529 1150172 830168..830659 1 NC_004342.2 hypothetical protein 830659 1150172 LA_0829 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711010.1 830168 D 189518 CDS NP_711013.2 294827742 1150175 831796..832554 1 NC_004342.2 biotin--[acetyl-CoA-carboxylase] ligase 832554 birA 1150175 birA Leptospira interrogans serovar Lai str. 56601 biotin--[acetyl-CoA-carboxylase] ligase NP_711013.2 831796 D 189518 CDS NP_711014.1 24213533 1150176 832556..833329 1 NC_004342.2 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 833329 1150176 LA_0833 Leptospira interrogans serovar Lai str. 56601 pantothenate kinase NP_711014.1 832556 D 189518 CDS NP_711016.1 24213535 1150178 complement(833957..835852) 1 NC_004342.2 hypothetical protein 835852 1150178 LA_0835 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711016.1 833957 R 189518 CDS NP_711017.2 294827743 1150179 complement(836038..836283) 1 NC_004342.2 hypothetical protein 836283 1150179 LA_0836 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711017.2 836038 R 189518 CDS NP_711019.1 24213538 1150181 complement(837858..839249) 1 NC_004342.2 UDP-N-acetylmuramoylalanine--D-glutamate ligase 839249 murD 1150181 murD Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylmuramoylalanine--D-glutamate ligase NP_711019.1 837858 R 189518 CDS NP_711020.1 24213539 1150182 839332..839664 1 NC_004342.2 anti-sigma factor antagonist 839664 spoIIAA 1150182 spoIIAA Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_711020.1 839332 D 189518 CDS NP_711021.1 24213540 1150183 839671..840429 1 NC_004342.2 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphat; indole-3-glycerol phosphate synthase 840429 trpC 1150183 trpC Leptospira interrogans serovar Lai str. 56601 indole-3-glycerol phosphate synthase NP_711021.1 839671 D 189518 CDS NP_711022.1 24213541 1150184 841517..842578 1 NC_004342.2 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 842578 1150184 LA_0841 Leptospira interrogans serovar Lai str. 56601 ribosomal RNA large subunit methyltransferase N NP_711022.1 841517 D 189518 CDS NP_711023.1 24213542 1150185 842609..842893 1 NC_004342.2 hypothetical protein 842893 1150185 LA_0842 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711023.1 842609 D 189518 CDS NP_711024.2 294827744 1150186 842908..844644 1 NC_004342.2 dolichyl-phosphate-mannose-protein mannosyltransferase 844644 1150186 LA_0843 Leptospira interrogans serovar Lai str. 56601 dolichyl-phosphate-mannose-protein mannosyltransferase NP_711024.2 842908 D 189518 CDS NP_711026.1 24213545 1150188 845690..846586 1 NC_004342.2 2-isopropylmalate synthase 846586 1150188 LA_0845 Leptospira interrogans serovar Lai str. 56601 2-isopropylmalate synthase NP_711026.1 845690 D 189518 CDS NP_711027.1 24213546 1150189 846583..847497 1 NC_004342.2 hypothetical protein 847497 1150189 LA_0846 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711027.1 846583 D 189518 CDS NP_711028.1 24213547 1150190 847562..848422 1 NC_004342.2 3-demethylubiquinone-9 3-methyltransferase 848422 1150190 LA_0847 Leptospira interrogans serovar Lai str. 56601 3-demethylubiquinone-9 3-methyltransferase NP_711028.1 847562 D 189518 CDS YP_003573297.1 294827745 9006885 848685..849053 1 NC_004342.2 hypothetical protein 849053 9006885 LA_0847a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573297.1 848685 D 189518 CDS NP_711030.1 24213549 1150192 849363..849677 1 NC_004342.2 50S ribosomal protein L21 849677 rplU 1150192 rplU Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L21 NP_711030.1 849363 D 189518 CDS NP_711031.1 24213550 1150193 849674..850000 1 NC_004342.2 hypothetical protein 850000 1150193 LA_0850 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711031.1 849674 D 189518 CDS NP_711032.1 24213551 1150194 849990..850244 1 NC_004342.2 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 850244 rpmA 1150194 rpmA Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L27 NP_711032.1 849990 D 189518 CDS NP_711033.1 24213552 1150195 850359..851429 1 NC_004342.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 851429 obgE 1150195 obgE Leptospira interrogans serovar Lai str. 56601 GTPase ObgE NP_711033.1 850359 D 189518 CDS NP_711034.1 24213553 1150196 851443..852315 1 NC_004342.2 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 852315 proB 1150196 proB Leptospira interrogans serovar Lai str. 56601 gamma-glutamyl kinase NP_711034.1 851443 D 189518 CDS YP_003573298.1 294827746 9006886 complement(852272..852679) 1 NC_004342.2 hypothetical protein 852679 9006886 LA_0853a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573298.1 852272 R 189518 CDS NP_711035.1 24213554 1150197 852312..853562 1 NC_004342.2 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 853562 proA 1150197 proA Leptospira interrogans serovar Lai str. 56601 gamma-glutamyl phosphate reductase NP_711035.1 852312 D 189518 CDS NP_711036.1 24213555 1150198 853566..854165 1 NC_004342.2 nicotinate-nucleotide adenylyltransferase 854165 nadD 1150198 nadD Leptospira interrogans serovar Lai str. 56601 nicotinate-nucleotide adenylyltransferase NP_711036.1 853566 D 189518 CDS NP_711039.2 294827747 1150201 855867..857069 1 NC_004342.2 hypothetical protein 857069 1150201 LA_0858 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711039.2 855867 D 189518 CDS NP_711041.1 24213560 1150203 857935..858174 1 NC_004342.2 hypothetical protein 858174 1150203 LA_0860 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711041.1 857935 D 189518 CDS NP_711042.1 24213561 1150204 858164..858568 1 NC_004342.2 anti-sigma factor antagonist 858568 spoIIAA 1150204 spoIIAA Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_711042.1 858164 D 189518 CDS NP_711043.1 24213562 1150205 complement(858925..859440) 1 NC_004342.2 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 859440 tpx 1150205 tpx Leptospira interrogans serovar Lai str. 56601 thiol peroxidase NP_711043.1 858925 R 189518 CDS NP_711046.1 24213565 1150208 861836..862150 1 NC_004342.2 hypothetical protein 862150 1150208 LA_0865 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711046.1 861836 D 189518 CDS NP_711047.1 24213566 1150209 complement(863397..864923) 1 NC_004342.2 HD family protein 864923 1150209 LA_0866 Leptospira interrogans serovar Lai str. 56601 HD family protein NP_711047.1 863397 R 189518 CDS NP_711050.2 294827748 1150212 866130..867593 1 NC_004342.2 aldehyde dehydrogenase 867593 putA 1150212 putA Leptospira interrogans serovar Lai str. 56601 aldehyde dehydrogenase NP_711050.2 866130 D 189518 CDS NP_711053.1 24213572 1150215 complement(868470..871136) 1 NC_004342.2 microbial collagenase 871136 1150215 LA_0872 Leptospira interrogans serovar Lai str. 56601 microbial collagenase NP_711053.1 868470 R 189518 CDS NP_711054.1 24213573 1150216 872673..873944 1 NC_004342.2 cytoplasmic membrane protein 873944 1150216 LA_0873 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_711054.1 872673 D 189518 CDS NP_711056.2 294827749 1150218 complement(874711..875607) 1 NC_004342.2 hypothetical protein 875607 1150218 LA_0875 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711056.2 874711 R 189518 CDS NP_711058.1 24213577 1150220 875669..876211 1 NC_004342.2 ECF-like sigma factor SigE 876211 1150220 LA_0876 Leptospira interrogans serovar Lai str. 56601 ECF-like sigma factor SigE NP_711058.1 875669 D 189518 CDS NP_711059.1 24213578 1150221 876222..877274 1 NC_004342.2 hypothetical protein 877274 1150221 LA_0878 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711059.1 876222 D 189518 CDS NP_711060.1 24213579 1150222 complement(877448..877918) 1 NC_004342.2 hypothetical protein 877918 1150222 LA_0879 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711060.1 877448 R 189518 CDS NP_711063.1 24213582 1150225 878853..879203 1 NC_004342.2 hypothetical protein 879203 1150225 LA_0882 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711063.1 878853 D 189518 CDS NP_711064.1 24213583 1150226 879257..879697 1 NC_004342.2 hypothetical protein 879697 1150226 LA_0883 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711064.1 879257 D 189518 CDS NP_711065.1 24213584 1150227 complement(880510..882048) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain N 882048 nuoN 1150227 nuoN Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain N NP_711065.1 880510 R 189518 CDS NP_711066.2 294827750 1150228 complement(882045..883286) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain M 883286 nuoM 1150228 nuoM Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain M NP_711066.2 882045 R 189518 CDS NP_711067.1 24213586 1150229 complement(883735..885696) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain L 885696 nuoL 1150229 nuoL Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain L NP_711067.1 883735 R 189518 CDS NP_711068.2 294827751 1150230 complement(885690..886010) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain K 886010 nuoK 1150230 nuoK Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain K NP_711068.2 885690 R 189518 CDS NP_711069.1 24213588 1150231 complement(886007..886708) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain J 886708 nuoJ 1150231 nuoJ Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain J NP_711069.1 886007 R 189518 CDS NP_711070.1 24213589 1150232 complement(886722..887762) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain H 887762 nuoH 1150232 nuoH Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain H NP_711070.1 886722 R 189518 CDS NP_711071.1 24213590 1150233 complement(887759..889090) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain F 889090 nuoF 1150233 nuoF Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain F NP_711071.1 887759 R 189518 CDS NP_711072.2 294827752 1150234 complement(889106..889585) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain E 889585 nuoE 1150234 nuoE Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain E NP_711072.2 889106 R 189518 CDS NP_711073.1 24213592 1150235 complement(889585..890802) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain D 890802 nuoD 1150235 nuoD Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain D NP_711073.1 889585 R 189518 CDS NP_711074.1 24213593 1150236 complement(890804..891340) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain C 891340 nuoC 1150236 nuoC Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain C NP_711074.1 890804 R 189518 CDS NP_711075.1 24213594 1150237 complement(891337..891897) 1 NC_004342.2 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 891897 nuoB 1150237 nuoB Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase subunit B NP_711075.1 891337 R 189518 CDS NP_711076.2 294827753 1150238 complement(891888..892265) 1 NC_004342.2 NADH dehydrogenase (ubiquinone) chain A 892265 nuoA 1150238 nuoA Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase (ubiquinone) chain A NP_711076.2 891888 R 189518 CDS NP_711079.2 294827754 1150241 892635..893288 1 NC_004342.2 hypothetical protein 893288 1150241 LA_0898 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711079.2 892635 D 189518 CDS NP_711080.1 24213599 1150242 893301..893765 1 NC_004342.2 MaoC-like acyl dehydratase 893765 maoC 1150242 maoC Leptospira interrogans serovar Lai str. 56601 MaoC-like acyl dehydratase NP_711080.1 893301 D 189518 CDS NP_711081.1 24213600 1150243 893796..894251 1 NC_004342.2 MarR family transcriptional regulator 894251 marR 1150243 marR Leptospira interrogans serovar Lai str. 56601 MarR family transcriptional regulator NP_711081.1 893796 D 189518 CDS NP_711084.1 24213603 1150246 895795..897426 1 NC_004342.2 methylase 897426 1150246 LA_0903 Leptospira interrogans serovar Lai str. 56601 methylase NP_711084.1 895795 D 189518 CDS NP_711086.2 294827755 1150248 898192..898926 1 NC_004342.2 hypothetical protein 898926 1150248 LA_0905 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711086.2 898192 D 189518 CDS NP_711087.1 24213606 1150249 complement(899501..899920) 1 NC_004342.2 hypothetical protein 899920 1150249 LA_0906 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711087.1 899501 R 189518 CDS NP_711089.1 24213608 1150251 complement(900319..901113) 1 NC_004342.2 hypothetical protein 901113 1150251 LA_0908 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711089.1 900319 R 189518 CDS NP_711090.1 24213609 1150252 901246..901692 1 NC_004342.2 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 901692 mgsA 1150252 mgsA Leptospira interrogans serovar Lai str. 56601 methylglyoxal synthase NP_711090.1 901246 D 189518 CDS NP_711092.2 294827756 1150254 902317..902943 1 NC_004342.2 hypothetical protein 902943 1150254 LA_0910 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711092.2 902317 D 189518 CDS NP_711093.1 24213612 1150255 complement(902940..904937) 1 NC_004342.2 TPR-repeat-containing protein 904937 1150255 LA_0912 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_711093.1 902940 R 189518 CDS NP_711094.1 24213613 1150256 complement(904934..906964) 1 NC_004342.2 NHL repeat protein 906964 1150256 LA_0913 Leptospira interrogans serovar Lai str. 56601 NHL repeat protein NP_711094.1 904934 R 189518 CDS YP_003573299.1 294827757 9006887 complement(907456..907659) 1 NC_004342.2 hypothetical protein 907659 9006887 LA_0913a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573299.1 907456 R 189518 CDS NP_711095.2 294827758 1150257 complement(907704..908219) 1 NC_004342.2 hypothetical protein 908219 1150257 LA_0914 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711095.2 907704 R 189518 CDS NP_711096.1 24213615 1150258 complement(909190..910131) 1 NC_004342.2 histone deacetylase 910131 acuC 1150258 acuC Leptospira interrogans serovar Lai str. 56601 histone deacetylase NP_711096.1 909190 R 189518 CDS NP_711097.2 294827759 1150259 910590..911768 1 NC_004342.2 hypothetical protein 911768 1150259 LA_0916 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711097.2 910590 D 189518 CDS NP_711099.1 24213618 1150261 complement(912868..913668) 1 NC_004342.2 enoyl-CoA hydratase 913668 caiD 1150261 caiD Leptospira interrogans serovar Lai str. 56601 enoyl-CoA hydratase NP_711099.1 912868 R 189518 CDS NP_711100.1 24213619 1150262 complement(913668..914195) 1 NC_004342.2 hypothetical protein 914195 1150262 LA_0919 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711100.1 913668 R 189518 CDS NP_711101.1 24213620 1150263 914829..916115 1 NC_004342.2 hypothetical protein 916115 1150263 LA_0920 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711101.1 914829 D 189518 CDS NP_711104.2 294827760 1150266 complement(917352..917723) 1 NC_004342.2 IS1533 transposase 917723 1150266 LA_0923 Leptospira interrogans serovar Lai str. 56601 IS1533 transposase NP_711104.2 917352 R 189518 CDS NP_711105.2 294827761 1150267 complement(917785..917964) 1 NC_004342.2 IS1533 transposase 917964 1150267 LA_0924 Leptospira interrogans serovar Lai str. 56601 IS1533 transposase NP_711105.2 917785 R 189518 CDS NP_711106.1 24213625 1150268 complement(918113..918373) 1 NC_004342.2 IS1533 transposase 918373 1150268 LA_0925 Leptospira interrogans serovar Lai str. 56601 IS1533 transposase NP_711106.1 918113 R 189518 CDS NP_711108.1 24213627 1150270 complement(918973..920214) 1 NC_004342.2 hypothetical protein 920214 1150270 LA_0927 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711108.1 918973 R 189518 CDS NP_711110.1 24213629 1150272 complement(921102..921806) 1 NC_004342.2 enolase 921806 1150272 LA_0929 Leptospira interrogans serovar Lai str. 56601 enolase NP_711110.1 921102 R 189518 CDS NP_711111.2 294827762 1150273 complement(921812..923194) 1 NC_004342.2 4-hydroxybenzoate transporter transmembrane protein 923194 1150273 LA_0930 Leptospira interrogans serovar Lai str. 56601 4-hydroxybenzoate transporter transmembrane protein NP_711111.2 921812 R 189518 CDS NP_711113.1 24213632 1150275 923448..924386 1 NC_004342.2 lysophospholipase 924386 pldB 1150275 pldB Leptospira interrogans serovar Lai str. 56601 lysophospholipase NP_711113.1 923448 D 189518 CDS NP_711115.1 24213634 1150277 926102..928018 1 NC_004342.2 hypothetical protein 928018 1150277 LA_0934 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711115.1 926102 D 189518 CDS NP_711116.1 24213635 1150278 complement(929203..930270) 1 NC_004342.2 hypothetical protein 930270 1150278 LA_0935 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711116.1 929203 R 189518 CDS NP_711117.1 24213636 1150279 complement(930387..930785) 1 NC_004342.2 hypothetical protein 930785 1150279 LA_0936 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711117.1 930387 R 189518 CDS NP_711118.2 294827763 1150280 complement(930787..930906) 1 NC_004342.2 hypothetical protein 930906 1150280 LA_0937 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711118.2 930787 R 189518 CDS NP_711119.1 24213638 1150281 complement(931659..932270) 1 NC_004342.2 hypothetical protein 932270 1150281 LA_0938 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711119.1 931659 R 189518 CDS NP_711120.1 24213639 1150282 complement(932272..934026) 1 NC_004342.2 hypothetical protein 934026 1150282 LA_0939 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711120.1 932272 R 189518 CDS NP_711121.1 24213640 1150283 complement(934017..935195) 1 NC_004342.2 hypothetical protein 935195 1150283 LA_0940 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711121.1 934017 R 189518 CDS NP_711122.2 294827764 1150284 935489..935860 1 NC_004342.2 hypothetical protein 935860 1150284 LA_0941 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711122.2 935489 D 189518 CDS NP_711123.1 24213642 1150285 935862..937244 1 NC_004342.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 937244 nusA 1150285 nusA Leptospira interrogans serovar Lai str. 56601 transcription elongation factor NusA NP_711123.1 935862 D 189518 CDS NP_711124.2 294827765 1150286 937309..939900 1 NC_004342.2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 939900 infB 1150286 infB Leptospira interrogans serovar Lai str. 56601 translation initiation factor IF-2 NP_711124.2 937309 D 189518 CDS NP_711125.1 24213644 1150287 939910..940263 1 NC_004342.2 ribosomal-binding factor A 940263 rbfA 1150287 rbfA Leptospira interrogans serovar Lai str. 56601 ribosomal-binding factor A NP_711125.1 939910 D 189518 CDS NP_711126.2 161484955 1150288 940220..941149 1 NC_004342.2 tRNA pseudouridine synthase B 941149 truB 1150288 truB Leptospira interrogans serovar Lai str. 56601 tRNA pseudouridine synthase B NP_711126.2 940220 D 189518 CDS NP_711127.2 161484954 1150289 941201..941467 1 NC_004342.2 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 941467 rpsO 1150289 rpsO Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S15 NP_711127.2 941201 D 189518 CDS NP_711128.1 24213647 1150290 941479..943575 1 NC_004342.2 polynucleotide phosphorylase 943575 pnp 1150290 pnp Leptospira interrogans serovar Lai str. 56601 polynucleotide phosphorylase NP_711128.1 941479 D 189518 CDS NP_711129.2 294827766 1150291 943597..944880 1 NC_004342.2 Zn-dependent peptidase 944880 pqqL 1150291 pqqL Leptospira interrogans serovar Lai str. 56601 Zn-dependent peptidase NP_711129.2 943597 D 189518 CDS NP_711131.2 294827767 1150293 945658..945888 1 NC_004342.2 hypothetical protein 945888 1150293 LA_0950 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711131.2 945658 D 189518 CDS NP_711135.1 24213654 1150297 948584..949909 1 NC_004342.2 hypothetical protein 949909 1150297 LA_0954 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711135.1 948584 D 189518 CDS NP_711137.1 24213656 1150299 950332..954828 1 NC_004342.2 glutamate synthase subunit alpha 954828 1150299 LA_0956 Leptospira interrogans serovar Lai str. 56601 glutamate synthase subunit alpha NP_711137.1 950332 D 189518 CDS NP_711138.1 24213657 1150300 complement(955815..957488) 1 NC_004342.2 TolC-like outer membrane efflux protein 957488 1150300 LA_0957 Leptospira interrogans serovar Lai str. 56601 TolC-like outer membrane efflux protein NP_711138.1 955815 R 189518 CDS NP_711139.2 294827769 1150301 957510..959654 1 NC_004342.2 hypothetical protein 959654 1150301 LA_0958 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711139.2 957510 D 189518 CDS NP_711140.1 24213659 1150302 960270..960548 1 NC_004342.2 hypothetical protein 960548 1150302 LA_0959 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711140.1 960270 D 189518 CDS NP_711143.1 24213662 1150305 complement(961818..964343) 1 NC_004342.2 hypothetical protein 964343 1150305 LA_0962 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711143.1 961818 R 189518 CDS NP_711145.1 24213664 1150307 complement(965052..966500) 1 NC_004342.2 ATP-dependent DNA helicase RecQ 966500 recQ 1150307 recQ Leptospira interrogans serovar Lai str. 56601 ATP-dependent DNA helicase RecQ NP_711145.1 965052 R 189518 CDS NP_711146.1 24213665 1150308 966605..970003 1 NC_004342.2 exodeoxyribonuclease V subunit gamma 970003 1150308 LA_0965 Leptospira interrogans serovar Lai str. 56601 exodeoxyribonuclease V subunit gamma NP_711146.1 966605 D 189518 CDS NP_711147.1 24213666 1150309 969993..973133 1 NC_004342.2 exodeoxyribonuclease V subunit beta 973133 1150309 LA_0966 Leptospira interrogans serovar Lai str. 56601 exodeoxyribonuclease V subunit beta NP_711147.1 969993 D 189518 CDS NP_711148.2 294827771 1150310 973130..974968 1 NC_004342.2 exodeoxyribonuclease V subunit alpha 974968 1150310 LA_0967 Leptospira interrogans serovar Lai str. 56601 exodeoxyribonuclease V subunit alpha NP_711148.2 973130 D 189518 CDS NP_711150.1 24213669 1150312 975282..976274 1 NC_004342.2 ABC transporter ATP-binding protein 976274 ccmA 1150312 ccmA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_711150.1 975282 D 189518 CDS NP_711151.1 24213670 1150313 976271..977032 1 NC_004342.2 ABC transporter permease 977032 1150313 LA_0970 Leptospira interrogans serovar Lai str. 56601 ABC transporter permease NP_711151.1 976271 D 189518 CDS NP_711152.2 294827772 1150314 977042..977899 1 NC_004342.2 short chain dehydrogenase 977899 fabG 1150314 fabG Leptospira interrogans serovar Lai str. 56601 short chain dehydrogenase NP_711152.2 977042 D 189518 CDS NP_711153.1 24213672 1150315 complement(979296..979616) 1 NC_004342.2 hypothetical protein 979616 1150315 LA_0973 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711153.1 979296 R 189518 CDS NP_711156.1 24213675 1150318 979982..981409 1 NC_004342.2 FimH-like protein 981409 1150318 LA_0975 Leptospira interrogans serovar Lai str. 56601 FimH-like protein NP_711156.1 979982 D 189518 CDS NP_711159.1 24213678 1150321 982071..983072 1 NC_004342.2 hypothetical protein 983072 1150321 LA_0978 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711159.1 982071 D 189518 CDS NP_711160.1 24213679 1150322 983311..984312 1 NC_004342.2 hypothetical protein 984312 1150322 LA_0979 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711160.1 983311 D 189518 CDS NP_711161.1 24213680 1150323 complement(984447..985934) 1 NC_004342.2 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 985934 thiC 1150323 thiC Leptospira interrogans serovar Lai str. 56601 thiamine biosynthesis protein ThiC NP_711161.1 984447 R 189518 CDS NP_711164.1 24213683 1150326 complement(987193..989319) 1 NC_004342.2 hypothetical protein 989319 1150326 LA_0983 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711164.1 987193 R 189518 CDS NP_711165.1 24213684 1150327 complement(989448..990953) 1 NC_004342.2 ATP-dependent DNA ligase 990953 cdc9 1150327 cdc9 Leptospira interrogans serovar Lai str. 56601 ATP-dependent DNA ligase NP_711165.1 989448 R 189518 CDS NP_711166.1 24213685 1150328 complement(991057..993030) 1 NC_004342.2 hypothetical protein 993030 1150328 LA_0985 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711166.1 991057 R 189518 CDS NP_711167.1 24213686 1150329 complement(993408..994553) 1 NC_004342.2 hypothetical protein 994553 1150329 LA_0986 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711167.1 993408 R 189518 CDS NP_711170.1 24213689 1150332 complement(995317..995781) 1 NC_004342.2 hypothetical protein 995781 1150332 LA_0989 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711170.1 995317 R 189518 CDS NP_711171.1 24213690 1150333 995847..996545 1 NC_004342.2 hypothetical protein 996545 1150333 LA_0990 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711171.1 995847 D 189518 CDS NP_711172.1 24213691 1150334 complement(996538..997374) 1 NC_004342.2 hypothetical protein 997374 1150334 LA_0991 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711172.1 996538 R 189518 CDS NP_711173.1 24213692 1150335 complement(997423..998433) 1 NC_004342.2 mechanosensitive ion channel 998433 1150335 LA_0992 Leptospira interrogans serovar Lai str. 56601 mechanosensitive ion channel NP_711173.1 997423 R 189518 CDS NP_711174.1 24213693 1150336 998581..1000830 1 NC_004342.2 guanylate cyclase 1000830 1150336 LA_0993 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_711174.1 998581 D 189518 CDS NP_711175.1 24213694 1150337 1000827..1002395 1 NC_004342.2 hypothetical protein 1002395 1150337 LA_0994 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711175.1 1000827 D 189518 CDS NP_711176.1 24213695 1150338 1002400..1003215 1 NC_004342.2 hypothetical protein 1003215 1150338 LA_0995 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711176.1 1002400 D 189518 CDS NP_711177.1 24213696 1150339 1003215..1003982 1 NC_004342.2 hypothetical protein 1003982 1150339 LA_0996 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711177.1 1003215 D 189518 CDS NP_711178.1 24213697 1150340 1004523..1005383 1 NC_004342.2 hypothetical protein 1005383 1150340 LA_0997 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711178.1 1004523 D 189518 CDS YP_003573300.1 294827773 9006888 complement(1005600..1006058) 1 NC_004342.2 acetyltransferase 1006058 9006888 LA_0997a Leptospira interrogans serovar Lai str. 56601 acetyltransferase YP_003573300.1 1005600 R 189518 CDS NP_711180.1 24213699 1150342 complement(1006059..1007135) 1 NC_004342.2 hypothetical protein 1007135 1150342 LA_0999 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711180.1 1006059 R 189518 CDS NP_711181.1 24213700 1150343 complement(1007277..1007825) 1 NC_004342.2 hypothetical protein 1007825 1150343 LA_1000 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711181.1 1007277 R 189518 CDS NP_711182.1 24213701 1150344 complement(1007923..1008321) 1 NC_004342.2 twitching motility protein PilT 1008321 vapC 1150344 vapC Leptospira interrogans serovar Lai str. 56601 twitching motility protein PilT NP_711182.1 1007923 R 189518 CDS NP_711183.1 24213702 1150345 complement(1008321..1008551) 1 NC_004342.2 virulence-associated protein VagC 1008551 vagC 1150345 vagC Leptospira interrogans serovar Lai str. 56601 virulence-associated protein VagC NP_711183.1 1008321 R 189518 CDS NP_711184.1 24213703 1150346 complement(1008799..1009476) 1 NC_004342.2 hypothetical protein 1009476 1150346 LA_1003 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711184.1 1008799 R 189518 CDS NP_711185.1 24213704 1150347 complement(1009708..1010397) 1 NC_004342.2 hypothetical protein 1010397 1150347 LA_1004 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711185.1 1009708 R 189518 CDS NP_711186.1 24213705 1150348 complement(1010623..1011081) 1 NC_004342.2 hypothetical protein 1011081 1150348 LA_1005 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711186.1 1010623 R 189518 CDS NP_711187.2 294827774 1150349 1011400..1012569 1 NC_004342.2 ISlin1 transposase 1012569 1150349 LA_1006 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_711187.2 1011400 D 189518 CDS NP_711188.1 24213707 1150350 1013237..1013806 1 NC_004342.2 glutathione peroxidase 1013806 btuE 1150350 btuE Leptospira interrogans serovar Lai str. 56601 glutathione peroxidase NP_711188.1 1013237 D 189518 CDS NP_711189.1 24213708 1150351 1014502..1015398 1 NC_004342.2 hypothetical protein 1015398 phuW 1150351 phuW Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711189.1 1014502 D 189518 CDS NP_711190.1 24213709 1150352 1015435..1018191 1 NC_004342.2 membrane carboxypeptidase/penicillin-binding protein 1018191 mrcA 1150352 mrcA Leptospira interrogans serovar Lai str. 56601 membrane carboxypeptidase/penicillin-binding protein NP_711190.1 1015435 D 189518 CDS NP_711191.1 24213710 1150353 1018181..1019740 1 NC_004342.2 hypothetical protein 1019740 1150353 LA_1010 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711191.1 1018181 D 189518 CDS NP_711194.2 294827775 1150356 1020778..1021776 1 NC_004342.2 hypothetical protein 1021776 1150356 LA_1013 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711194.2 1020778 D 189518 CDS NP_711195.1 24213714 1150357 complement(1021950..1022375) 1 NC_004342.2 hypothetical protein 1022375 1150357 LA_1014 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711195.1 1021950 R 189518 CDS NP_711196.1 24213715 1150358 complement(1022625..1023242) 1 NC_004342.2 hypothetical protein 1023242 1150358 LA_1015 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711196.1 1022625 R 189518 CDS NP_711197.1 24213716 1150359 complement(1023247..1025415) 1 NC_004342.2 hypothetical protein 1025415 1150359 LA_1016 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711197.1 1023247 R 189518 CDS NP_711198.1 24213717 1150360 complement(1025412..1026245) 1 NC_004342.2 TPR-repeat-containing protein 1026245 1150360 LA_1017 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_711198.1 1025412 R 189518 CDS NP_711199.1 24213718 1150361 complement(1026558..1026746) 1 NC_004342.2 hypothetical protein 1026746 1150361 LA_1018 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711199.1 1026558 R 189518 CDS NP_711200.1 24213719 1150362 complement(1026743..1027534) 1 NC_004342.2 hypothetical protein 1027534 1150362 LA_1019 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711200.1 1026743 R 189518 CDS NP_711201.1 24213720 1150363 complement(1027593..1027796) 1 NC_004342.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1027796 rpmE 1150363 rpmE Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L31 NP_711201.1 1027593 R 189518 CDS NP_711202.1 24213721 1150364 complement(1027817..1029265) 1 NC_004342.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1029265 rho 1150364 rho Leptospira interrogans serovar Lai str. 56601 transcription termination factor Rho NP_711202.1 1027817 R 189518 CDS NP_711203.1 24213722 1150365 complement(1029413..1030576) 1 NC_004342.2 transcriptional regulator 1030576 1150365 LA_1022 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711203.1 1029413 R 189518 CDS NP_711204.2 294827776 1150366 1031074..1034553 1 NC_004342.2 hypothetical protein 1034553 1150366 LA_1023 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711204.2 1031074 D 189518 CDS NP_711205.1 24213724 1150367 1034562..1035587 1 NC_004342.2 hypothetical protein 1035587 1150367 LA_1024 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711205.1 1034562 D 189518 CDS NP_711208.2 294827777 1150370 complement(1036351..1038054) 1 NC_004342.2 sphingomyelinase C precursor 1038054 1150370 LA_1027 Leptospira interrogans serovar Lai str. 56601 sphingomyelinase C precursor NP_711208.2 1036351 R 189518 CDS NP_711210.2 294827778 1150372 complement(1039059..1040882) 1 NC_004342.2 sphingomyelinase C precursor 1040882 1150372 LA_1029 Leptospira interrogans serovar Lai str. 56601 sphingomyelinase C precursor NP_711210.2 1039059 R 189518 CDS NP_711211.1 24213730 1150373 complement(1041580..1042428) 1 NC_004342.2 TPR-repeat-containing protein 1042428 1150373 LA_1030 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_711211.1 1041580 R 189518 CDS NP_711212.1 24213731 1150374 1042540..1042719 1 NC_004342.2 hypothetical protein 1042719 1150374 LA_1031 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711212.1 1042540 D 189518 CDS NP_711213.1 24213732 1150375 complement(1042721..1043548) 1 NC_004342.2 enoyl-CoA hydratase 1043548 caiD 1150375 caiD Leptospira interrogans serovar Lai str. 56601 enoyl-CoA hydratase NP_711213.1 1042721 R 189518 CDS NP_711214.2 294827779 1150376 1043659..1043853 1 NC_004342.2 hypothetical protein 1043853 1150376 LA_1033 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711214.2 1043659 D 189518 CDS NP_711217.1 24213736 1150379 complement(1045500..1046879) 1 NC_004342.2 histidine kinase/response regulator hybrid protein 1046879 1150379 LA_1036 Leptospira interrogans serovar Lai str. 56601 histidine kinase/response regulator hybrid protein NP_711217.1 1045500 R 189518 CDS NP_711218.1 24213737 1150380 complement(1047206..1047376) 1 NC_004342.2 hypothetical protein 1047376 1150380 LA_1037 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711218.1 1047206 R 189518 CDS NP_711220.1 24213739 1150382 complement(1047797..1048471) 1 NC_004342.2 hypothetical protein 1048471 1150382 LA_1039 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711220.1 1047797 R 189518 CDS NP_711221.1 24213740 1150383 complement(1048575..1049657) 1 NC_004342.2 hypothetical protein 1049657 1150383 LA_1040 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711221.1 1048575 R 189518 CDS NP_711224.1 24213743 1150386 complement(1050395..1051513) 1 NC_004342.2 M23 family metalloendopeptidase 1051513 nlpD 1150386 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_711224.1 1050395 R 189518 CDS NP_711225.1 24213744 1150387 complement(1051567..1051977) 1 NC_004342.2 cell shape determination protein 1051977 1150387 LA_1044 Leptospira interrogans serovar Lai str. 56601 cell shape determination protein NP_711225.1 1051567 R 189518 CDS NP_711226.1 24213745 1150388 complement(1052079..1054562) 1 NC_004342.2 membrane carboxypeptidase/penicillin-binding protein 1054562 mrcA 1150388 mrcA Leptospira interrogans serovar Lai str. 56601 membrane carboxypeptidase/penicillin-binding protein NP_711226.1 1052079 R 189518 CDS NP_711227.1 24213746 1150389 complement(1054569..1055645) 1 NC_004342.2 hypothetical protein 1055645 1150389 LA_1046 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711227.1 1054569 R 189518 CDS NP_711228.1 24213747 1150390 1055721..1056989 1 NC_004342.2 diaminopimelate decarboxylase 1056989 lysA 1150390 lysA Leptospira interrogans serovar Lai str. 56601 diaminopimelate decarboxylase NP_711228.1 1055721 D 189518 CDS NP_711229.1 24213748 1150391 1056967..1057683 1 NC_004342.2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1057683 ispD 1150391 ispD Leptospira interrogans serovar Lai str. 56601 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NP_711229.1 1056967 D 189518 CDS NP_711232.1 24213751 1150394 1059275..1059799 1 NC_004342.2 hypothetical protein 1059799 1150394 LA_1051 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711232.1 1059275 D 189518 CDS NP_711233.1 24213752 1150395 1059796..1061175 1 NC_004342.2 hypothetical protein 1061175 1150395 LA_1052 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711233.1 1059796 D 189518 CDS NP_711234.1 24213753 1150396 1061189..1061599 1 NC_004342.2 hypothetical protein 1061599 1150396 LA_1053 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711234.1 1061189 D 189518 CDS NP_711235.1 24213754 1150397 1061596..1061916 1 NC_004342.2 hypothetical protein 1061916 1150397 LA_1054 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711235.1 1061596 D 189518 CDS NP_711236.1 24213755 1150398 1062023..1062241 1 NC_004342.2 hypothetical protein 1062241 1150398 LA_1055 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711236.1 1062023 D 189518 CDS NP_711237.2 294827780 1150399 1062302..1064107 1 NC_004342.2 hypothetical protein 1064107 1150399 LA_1056 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711237.2 1062302 D 189518 CDS NP_711238.1 24213757 1150400 1064104..1064715 1 NC_004342.2 hypothetical protein 1064715 1150400 LA_1057 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711238.1 1064104 D 189518 CDS NP_711239.1 24213758 1150401 1064733..1065071 1 NC_004342.2 hypothetical protein 1065071 1150401 LA_1058 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711239.1 1064733 D 189518 CDS NP_711240.1 24213759 1150402 1065068..1065886 1 NC_004342.2 hypothetical protein 1065886 1150402 LA_1059 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711240.1 1065068 D 189518 CDS NP_711241.2 294827781 1150403 1065883..1066566 1 NC_004342.2 hypothetical protein 1066566 1150403 LA_1060 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711241.2 1065883 D 189518 CDS NP_711242.1 24213761 1150404 1066563..1066907 1 NC_004342.2 hypothetical protein 1066907 1150404 LA_1061 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711242.1 1066563 D 189518 CDS NP_711243.2 294827782 1150405 1066907..1068121 1 NC_004342.2 hypothetical protein 1068121 1150405 LA_1062 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711243.2 1066907 D 189518 CDS NP_711244.1 24213763 1150406 1068118..1069092 1 NC_004342.2 hypothetical protein 1069092 1150406 LA_1063 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711244.1 1068118 D 189518 CDS NP_711245.1 24213764 1150407 1069089..1069364 1 NC_004342.2 hypothetical protein 1069364 1150407 LA_1064 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711245.1 1069089 D 189518 CDS NP_711246.2 294827783 1150408 1069367..1070254 1 NC_004342.2 hypothetical protein 1070254 1150408 LA_1065 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711246.2 1069367 D 189518 CDS NP_711247.2 294827784 1150409 1070399..1071289 1 NC_004342.2 hypothetical protein 1071289 1150409 LA_1066 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711247.2 1070399 D 189518 CDS NP_711248.1 24213767 1150410 1071289..1072020 1 NC_004342.2 hypothetical protein 1072020 1150410 LA_1067 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711248.1 1071289 D 189518 CDS NP_711250.1 24213769 1150412 complement(1073023..1073886) 1 NC_004342.2 hydrolase 1073886 1150412 LA_1069 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_711250.1 1073023 R 189518 CDS NP_711251.1 24213770 1150413 complement(1074012..1075112) 1 NC_004342.2 guanylate cyclase 1075112 cyaA 1150413 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_711251.1 1074012 R 189518 CDS NP_711252.1 24213771 1150414 complement(1075118..1075309) 1 NC_004342.2 guanylate cyclase 1075309 1150414 LA_1071 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_711252.1 1075118 R 189518 CDS NP_711253.1 24213772 1150415 complement(1075974..1077059) 1 NC_004342.2 hypothetical protein 1077059 1150415 LA_1072 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711253.1 1075974 R 189518 CDS NP_711254.2 294827785 1150416 complement(1077171..1077695) 1 NC_004342.2 hypothetical protein 1077695 1150416 LA_1073 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711254.2 1077171 R 189518 CDS NP_711255.1 24213774 1150417 complement(1078429..1079379) 1 NC_004342.2 fumarylacetoacetate hydrolase family protein 1079379 mhpD 1150417 mhpD Leptospira interrogans serovar Lai str. 56601 fumarylacetoacetate hydrolase family protein NP_711255.1 1078429 R 189518 CDS NP_711260.2 294827786 1150422 complement(1082130..1082822) 1 NC_004342.2 hypothetical protein 1082822 1150422 LA_1079 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711260.2 1082130 R 189518 CDS NP_711261.1 24213780 1150423 complement(1082858..1085512) 1 NC_004342.2 aminopeptidase 1085512 1150423 LA_1080 Leptospira interrogans serovar Lai str. 56601 aminopeptidase NP_711261.1 1082858 R 189518 CDS NP_711262.2 294827787 1150424 complement(1085652..1086908) 1 NC_004342.2 drug proton antiporter 1086908 1150424 LA_1081 Leptospira interrogans serovar Lai str. 56601 drug proton antiporter NP_711262.2 1085652 R 189518 CDS NP_711263.1 24213782 1150425 complement(1086910..1087488) 1 NC_004342.2 ADP-ribose pyrophosphatase 1087488 1150425 LA_1082 Leptospira interrogans serovar Lai str. 56601 ADP-ribose pyrophosphatase NP_711263.1 1086910 R 189518 CDS NP_711266.1 24213785 1150428 1087995..1090019 1 NC_004342.2 DNA helicase UvrD 1090019 uvrD 1150428 uvrD Leptospira interrogans serovar Lai str. 56601 DNA helicase UvrD NP_711266.1 1087995 D 189518 CDS NP_711267.1 24213786 1150429 1090022..1090672 1 NC_004342.2 TPR-repeat lipoprotein 1090672 1150429 LA_1086 Leptospira interrogans serovar Lai str. 56601 TPR-repeat lipoprotein NP_711267.1 1090022 D 189518 CDS NP_711268.1 24213787 1150430 1090690..1092882 1 NC_004342.2 hypothetical protein 1092882 1150430 LA_1087 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711268.1 1090690 D 189518 CDS NP_711269.1 24213788 1150431 1092852..1093256 1 NC_004342.2 hypothetical protein 1093256 1150431 LA_1088 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711269.1 1092852 D 189518 CDS NP_711271.2 294827788 1150433 1093829..1094230 1 NC_004342.2 hypothetical protein 1094230 1150433 LA_1090 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711271.2 1093829 D 189518 CDS NP_711272.2 294827789 1150434 complement(1094348..1094680) 1 NC_004342.2 transcriptional regulator 1094680 arsR 1150434 arsR Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711272.2 1094348 R 189518 CDS NP_711273.1 24213792 1150435 1094731..1095213 1 NC_004342.2 hypothetical protein 1095213 1150435 LA_1092 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711273.1 1094731 D 189518 CDS NP_711274.1 24213793 1150436 complement(1095345..1095767) 1 NC_004342.2 hypothetical protein 1095767 1150436 LA_1093 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711274.1 1095345 R 189518 CDS NP_711275.2 294827790 1150437 1096386..1096622 1 NC_004342.2 aminoglycoside N6'-acetyltransferase 1096622 1150437 LA_1094 Leptospira interrogans serovar Lai str. 56601 aminoglycoside N6'-acetyltransferase NP_711275.2 1096386 D 189518 CDS NP_711276.1 24213795 1150438 1096619..1096840 1 NC_004342.2 acetyltransferase 1096840 1150438 LA_1095 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_711276.1 1096619 D 189518 CDS NP_711277.2 294827791 1150439 complement(1097355..1098551) 1 NC_004342.2 lipid-A-disaccharide synthase 1098551 lpxB 1150439 lpxB Leptospira interrogans serovar Lai str. 56601 lipid-A-disaccharide synthase NP_711277.2 1097355 R 189518 CDS NP_711278.1 24213797 1150440 complement(1098604..1099452) 1 NC_004342.2 hypothetical protein 1099452 1150440 LA_1097 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711278.1 1098604 R 189518 CDS NP_711279.1 24213798 1150441 complement(1099465..1099707) 1 NC_004342.2 hypothetical protein 1099707 1150441 LA_1098 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711279.1 1099465 R 189518 CDS NP_711280.1 24213799 1150442 complement(1099746..1101179) 1 NC_004342.2 hypothetical protein 1101179 1150442 LA_1099 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711280.1 1099746 R 189518 CDS NP_711281.2 294827792 1150443 complement(1101201..1102778) 1 NC_004342.2 cytoplasmic membrane protein 1102778 1150443 LA_1100 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_711281.2 1101201 R 189518 CDS NP_711282.1 24213801 1150444 complement(1103065..1103940) 1 NC_004342.2 succinyl-CoA synthetase subunit alpha 1103940 sucD 1150444 sucD Leptospira interrogans serovar Lai str. 56601 succinyl-CoA synthetase subunit alpha NP_711282.1 1103065 R 189518 CDS NP_711283.1 24213802 1150445 complement(1103953..1105125) 1 NC_004342.2 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1105125 sucC 1150445 sucC Leptospira interrogans serovar Lai str. 56601 succinyl-CoA synthetase subunit beta NP_711283.1 1103953 R 189518 CDS NP_711284.1 24213803 1150446 complement(1106334..1106978) 1 NC_004342.2 hypothetical protein 1106978 1150446 LA_1103 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711284.1 1106334 R 189518 CDS NP_711285.1 24213804 1150447 complement(1106947..1107576) 1 NC_004342.2 DnaJ-like protein 1107576 1150447 LA_1104 Leptospira interrogans serovar Lai str. 56601 DnaJ-like protein NP_711285.1 1106947 R 189518 CDS NP_711286.1 24213805 1150448 1107676..1109025 1 NC_004342.2 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1109025 miaB 1150448 miaB Leptospira interrogans serovar Lai str. 56601 (dimethylallyl)adenosine tRNA methylthiotransferase NP_711286.1 1107676 D 189518 CDS NP_711287.1 24213806 1150449 1109022..1110917 1 NC_004342.2 hypothetical protein 1110917 1150449 LA_1106 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711287.1 1109022 D 189518 CDS NP_711288.1 24213807 1150450 1110949..1111785 1 NC_004342.2 hypothetical protein 1111785 1150450 LA_1107 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711288.1 1110949 D 189518 CDS NP_711291.1 24213810 1150453 complement(1113304..1114581) 1 NC_004342.2 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1114581 purA 1150453 purA Leptospira interrogans serovar Lai str. 56601 adenylosuccinate synthetase NP_711291.1 1113304 R 189518 CDS NP_711292.1 24213811 1150454 complement(1114619..1115653) 1 NC_004342.2 ATP phosphoribosyltransferase 1115653 1150454 LA_1111 Leptospira interrogans serovar Lai str. 56601 ATP phosphoribosyltransferase NP_711292.1 1114619 R 189518 CDS NP_711293.1 24213812 1150455 1115960..1117969 1 NC_004342.2 glycerol-3-phosphate dehydrogenase 1117969 gpsA 1150455 gpsA Leptospira interrogans serovar Lai str. 56601 glycerol-3-phosphate dehydrogenase NP_711293.1 1115960 D 189518 CDS NP_711295.1 24213814 1150457 1118575..1119708 1 NC_004342.2 ring hydroxylating dioxygenase subunit alpha 1119708 1150457 LA_1114 Leptospira interrogans serovar Lai str. 56601 ring hydroxylating dioxygenase subunit alpha NP_711295.1 1118575 D 189518 CDS NP_711298.1 24213817 1150460 complement(1121412..1122362) 1 NC_004342.2 hypothetical protein 1122362 1150460 LA_1118 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711298.1 1121412 R 189518 CDS NP_711300.1 24213819 1150462 1122868..1123305 1 NC_004342.2 dUTP diphosphatase 1123305 dut 1150462 dut Leptospira interrogans serovar Lai str. 56601 dUTP diphosphatase NP_711300.1 1122868 D 189518 CDS NP_711302.1 24213821 1150464 1124476..1124997 1 NC_004342.2 hypothetical protein 1124997 1150464 LA_1121 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711302.1 1124476 D 189518 CDS NP_711303.2 294827793 1150465 complement(1125170..1126123) 1 NC_004342.2 hypothetical protein 1126123 1150465 LA_1122 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711303.2 1125170 R 189518 CDS NP_711304.2 294827794 1150466 complement(1126680..1127450) 1 NC_004342.2 exonuclease 1127450 1150466 LA_1123 Leptospira interrogans serovar Lai str. 56601 exonuclease NP_711304.2 1126680 R 189518 CDS NP_711305.2 294827795 1150467 complement(1127450..1128997) 1 NC_004342.2 apolipoprotein n-acyltransferase 1128997 1150467 LA_1124 Leptospira interrogans serovar Lai str. 56601 apolipoprotein n-acyltransferase NP_711305.2 1127450 R 189518 CDS YP_003573301.1 294827796 9006892 1129023..1129175 1 NC_004342.2 hypothetical protein 1129175 9006892 LA_1124a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573301.1 1129023 D 189518 CDS NP_711306.1 24213825 1150468 complement(1129186..1130220) 1 NC_004342.2 hypothetical protein 1130220 1150468 LA_1125 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711306.1 1129186 R 189518 CDS NP_711307.1 24213826 1150469 1130307..1131326 1 NC_004342.2 phosphoglycerate dehydrogenase and related dehydrogenase 1131326 serA 1150469 serA Leptospira interrogans serovar Lai str. 56601 phosphoglycerate dehydrogenase and related dehydrogenase NP_711307.1 1130307 D 189518 CDS NP_711309.1 24213828 1150471 complement(1132663..1133565) 1 NC_004342.2 DNA repair photolyase SplB 1133565 splB 1150471 splB Leptospira interrogans serovar Lai str. 56601 DNA repair photolyase SplB NP_711309.1 1132663 R 189518 CDS NP_711310.1 24213829 1150472 complement(1133543..1134229) 1 NC_004342.2 DNA alkylation repair enzyme-like protein 1134229 1150472 LA_1129 Leptospira interrogans serovar Lai str. 56601 DNA alkylation repair enzyme-like protein NP_711310.1 1133543 R 189518 CDS NP_711311.1 24213830 1150473 complement(1134403..1136103) 1 NC_004342.2 acyl-CoA dehydrogenase 1136103 1150473 LA_1130 Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_711311.1 1134403 R 189518 CDS NP_711312.1 24213831 1150474 complement(1136274..1136939) 1 NC_004342.2 protein-L-isoaspartate O-methyltransferase 1136939 pcm 1150474 pcm Leptospira interrogans serovar Lai str. 56601 protein-L-isoaspartate O-methyltransferase NP_711312.1 1136274 R 189518 CDS NP_711313.1 24213832 1150475 complement(1137118..1137360) 1 NC_004342.2 hypothetical protein 1137360 1150475 LA_1132 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711313.1 1137118 R 189518 CDS NP_711314.1 24213833 1150476 1137460..1137891 1 NC_004342.2 hypothetical protein 1137891 1150476 LA_1133 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711314.1 1137460 D 189518 CDS YP_003573302.1 294827797 9006894 1138323..1138502 1 NC_004342.2 hypothetical protein 1138502 9006894 LA_1133a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573302.1 1138323 D 189518 CDS NP_711316.2 294827798 1150478 1139228..1140397 1 NC_004342.2 hypothetical protein 1140397 1150478 LA_1135 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711316.2 1139228 D 189518 CDS NP_711317.1 24213836 1150479 1140856..1141629 1 NC_004342.2 outer membrane lipoprotein-sorting protein 1141629 1150479 LA_1136 Leptospira interrogans serovar Lai str. 56601 outer membrane lipoprotein-sorting protein NP_711317.1 1140856 D 189518 CDS NP_711318.1 24213837 1150480 1141651..1142766 1 NC_004342.2 hypothetical protein 1142766 1150480 LA_1137 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711318.1 1141651 D 189518 CDS NP_711319.1 24213838 1150481 1142775..1144088 1 NC_004342.2 2-methylthioadenine synthetase 1144088 miaB 1150481 miaB Leptospira interrogans serovar Lai str. 56601 2-methylthioadenine synthetase NP_711319.1 1142775 D 189518 CDS NP_711320.2 294827799 1150482 1144085..1144831 1 NC_004342.2 CDP-diacylglycerol--glycerol-3-phosphate 3- phosphatidyltransferase 1144831 pgsA 1150482 pgsA Leptospira interrogans serovar Lai str. 56601 CDP-diacylglycerol--glycerol-3-phosphate 3- phosphatidyltransferase NP_711320.2 1144085 D 189518 CDS NP_711321.1 24213840 1150483 1144806..1145816 1 NC_004342.2 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1145816 trpD 1150483 trpD Leptospira interrogans serovar Lai str. 56601 anthranilate phosphoribosyltransferase NP_711321.1 1144806 D 189518 CDS NP_711322.1 24213841 1150484 1145872..1146198 1 NC_004342.2 preprotein translocase subunit YajC 1146198 yajC 1150484 yajC Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit YajC NP_711322.1 1145872 D 189518 CDS YP_003573303.1 294827800 9006895 1146195..1146941 1 NC_004342.2 hypothetical protein 1146941 9006895 LA_1141a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573303.1 1146195 D 189518 CDS NP_711323.2 294827801 1150485 1146952..1148880 1 NC_004342.2 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1148880 secD 1150485 secD Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit SecD NP_711323.2 1146952 D 189518 CDS NP_711324.2 294827802 1150486 1148885..1149823 1 NC_004342.2 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1149823 secF 1150486 secF Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit SecF NP_711324.2 1148885 D 189518 CDS NP_711325.1 24213844 1150487 1149823..1151223 1 NC_004342.2 pyrimidine deaminase, riboflavin biosynthesis 1151223 1150487 LA_1144 Leptospira interrogans serovar Lai str. 56601 pyrimidine deaminase, riboflavin biosynthesis NP_711325.1 1149823 D 189518 CDS NP_711326.2 294827803 1150488 1151208..1151810 1 NC_004342.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1151810 ribC 1150488 ribC Leptospira interrogans serovar Lai str. 56601 riboflavin synthase subunit alpha NP_711326.2 1151208 D 189518 CDS NP_711328.1 24213847 1150490 1153454..1154659 1 NC_004342.2 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II 1154659 ribB 1150490 ribB Leptospira interrogans serovar Lai str. 56601 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II NP_711328.1 1153454 D 189518 CDS NP_711333.1 24213852 1150495 1156119..1156805 1 NC_004342.2 hypothetical protein 1156805 1150495 LA_1152 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711333.1 1156119 D 189518 CDS NP_711336.1 24213855 1150498 1158790..1159797 1 NC_004342.2 sulfate ABC transporter substrate-binding protein 1159797 sbp 1150498 sbp Leptospira interrogans serovar Lai str. 56601 sulfate ABC transporter substrate-binding protein NP_711336.1 1158790 D 189518 CDS NP_711337.2 294827804 1150499 1159831..1160661 1 NC_004342.2 sulfate ABC transporter permease 1160661 cysU 1150499 cysU Leptospira interrogans serovar Lai str. 56601 sulfate ABC transporter permease NP_711337.2 1159831 D 189518 CDS NP_711338.1 24213857 1150500 1160658..1161497 1 NC_004342.2 sulfate ABC transporter permease 1161497 cysW 1150500 cysW Leptospira interrogans serovar Lai str. 56601 sulfate ABC transporter permease NP_711338.1 1160658 D 189518 CDS NP_711339.2 294827805 1150501 1161499..1162569 1 NC_004342.2 ABC transporter ATP-binding protein 1162569 cysA 1150501 cysA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_711339.2 1161499 D 189518 CDS NP_711340.1 24213859 1150502 complement(1163100..1164308) 1 NC_004342.2 hypothetical protein 1164308 1150502 LA_1159 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711340.1 1163100 R 189518 CDS NP_711342.2 294827806 1150504 complement(1165945..1167351) 1 NC_004342.2 fatty acid transport protein 1167351 1150504 LA_1161 Leptospira interrogans serovar Lai str. 56601 fatty acid transport protein NP_711342.2 1165945 R 189518 CDS NP_711343.1 24213862 1150505 1167449..1168567 1 NC_004342.2 hypothetical protein 1168567 1150505 LA_1162 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711343.1 1167449 D 189518 CDS NP_711344.1 24213863 1150506 1168572..1169237 1 NC_004342.2 hypothetical protein 1169237 1150506 LA_1163 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711344.1 1168572 D 189518 CDS NP_711345.1 24213864 1150507 1169247..1174526 1 NC_004342.2 serine/threonine kinase 1174526 1150507 LA_1164 Leptospira interrogans serovar Lai str. 56601 serine/threonine kinase NP_711345.1 1169247 D 189518 CDS NP_711347.1 24213866 1150509 1174948..1175592 1 NC_004342.2 pyridoxamine-phosphate oxidase 1175592 pdxH 1150509 pdxH Leptospira interrogans serovar Lai str. 56601 pyridoxamine-phosphate oxidase NP_711347.1 1174948 D 189518 CDS NP_711348.2 294827807 1150510 1175763..1176179 1 NC_004342.2 hypothetical protein 1176179 1150510 LA_1167 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711348.2 1175763 D 189518 CDS NP_711349.1 24213868 1150511 1176176..1176595 1 NC_004342.2 hypothetical protein 1176595 1150511 LA_1168 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711349.1 1176176 D 189518 CDS NP_711353.1 24213872 1150515 complement(1177459..1177863) 1 NC_004342.2 hypothetical protein 1177863 1150515 LA_1172 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711353.1 1177459 R 189518 CDS NP_711354.1 24213873 1150516 1177996..1179978 1 NC_004342.2 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 1179978 acs 1150516 acs Leptospira interrogans serovar Lai str. 56601 acetoacetyl-CoA synthetase NP_711354.1 1177996 D 189518 CDS NP_711355.1 24213874 1150517 1180485..1181477 1 NC_004342.2 ABC transporter substrate-binding protein 1181477 1150517 LA_1174 Leptospira interrogans serovar Lai str. 56601 ABC transporter substrate-binding protein NP_711355.1 1180485 D 189518 CDS NP_711356.2 294827808 1150518 1181683..1183464 1 NC_004342.2 DNA mismatch repair protein MutL 1183464 mutL 1150518 mutL Leptospira interrogans serovar Lai str. 56601 DNA mismatch repair protein MutL NP_711356.2 1181683 D 189518 CDS NP_711357.1 24213876 1150519 1183433..1184053 1 NC_004342.2 cytoplasmic membrane protein 1184053 1150519 LA_1176 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_711357.1 1183433 D 189518 CDS NP_711358.2 294827809 1150520 complement(1184177..1184536) 1 NC_004342.2 hypothetical protein 1184536 1150520 LA_1177 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711358.2 1184177 R 189518 CDS NP_711359.1 24213878 1150521 1184749..1184976 1 NC_004342.2 hypothetical protein 1184976 1150521 LA_1178 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711359.1 1184749 D 189518 CDS NP_711360.1 24213879 1150522 1184973..1186244 1 NC_004342.2 recombination factor protein RarA 1186244 1150522 LA_1179 Leptospira interrogans serovar Lai str. 56601 recombination factor protein RarA NP_711360.1 1184973 D 189518 CDS NP_711361.1 24213880 1150523 complement(1186245..1186562) 1 NC_004342.2 hypothetical protein 1186562 1150523 LA_1180 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711361.1 1186245 R 189518 CDS NP_711362.1 24213881 1150524 complement(1187233..1188345) 1 NC_004342.2 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1188345 hisC 1150524 hisC Leptospira interrogans serovar Lai str. 56601 histidinol-phosphate aminotransferase NP_711362.1 1187233 R 189518 CDS NP_711363.1 24213882 1150525 1188344..1188469 1 NC_004342.2 hypothetical protein 1188469 1150525 LA_1181 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711363.1 1188344 D 189518 CDS NP_711364.2 294827810 1150526 1188487..1188657 1 NC_004342.2 hypothetical protein 1188657 1150526 LA_1183 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711364.2 1188487 D 189518 CDS NP_711365.1 24213884 1150527 complement(1188659..1190251) 1 NC_004342.2 guanylate cyclase 1190251 cyaA 1150527 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_711365.1 1188659 R 189518 CDS NP_711366.1 24213885 1150528 1190433..1192142 1 NC_004342.2 signal transduction protein 1192142 1150528 LA_1185 Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_711366.1 1190433 D 189518 CDS NP_711367.1 24213886 1150529 1192263..1192652 1 NC_004342.2 two-component response regulator 1192652 1150529 LA_1186 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_711367.1 1192263 D 189518 CDS NP_711369.1 24213888 1150531 1193808..1194257 1 NC_004342.2 hypothetical protein 1194257 1150531 LA_1188 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711369.1 1193808 D 189518 CDS NP_711370.1 24213889 1150532 1194422..1194709 1 NC_004342.2 sigma 54 modulation protein 1194709 1150532 LA_1189 Leptospira interrogans serovar Lai str. 56601 sigma 54 modulation protein NP_711370.1 1194422 D 189518 CDS NP_711371.1 24213890 1150533 1194761..1195702 1 NC_004342.2 hypothetical protein 1195702 1150533 LA_1190 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711371.1 1194761 D 189518 CDS NP_711372.1 24213891 1150534 complement(1195731..1197806) 1 NC_004342.2 methyl-accepting chemotaxis protein 1197806 1150534 LA_1191 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_711372.1 1195731 R 189518 CDS NP_711373.1 24213892 1150535 complement(1197832..1199403) 1 NC_004342.2 hypothetical protein 1199403 1150535 LA_1192 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711373.1 1197832 R 189518 CDS YP_003573304.1 294827811 9006896 complement(1199393..1199587) 1 NC_004342.2 hypothetical protein 1199587 9006896 LA_1192a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573304.1 1199393 R 189518 CDS NP_711376.2 294827812 1150538 complement(1200271..1201296) 1 NC_004342.2 hypothetical protein 1201296 1150538 LA_1196 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711376.2 1200271 R 189518 CDS NP_711377.2 294827813 1150539 1201406..1201789 1 NC_004342.2 hypothetical protein 1201789 1150539 LA_1195 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711377.2 1201406 D 189518 CDS NP_711378.2 294827814 1150540 1201764..1203146 1 NC_004342.2 serine phosphatase RsbU 1203146 rsbU 1150540 rsbU Leptospira interrogans serovar Lai str. 56601 serine phosphatase RsbU NP_711378.2 1201764 D 189518 CDS NP_711379.1 24213898 1150541 1203154..1203927 1 NC_004342.2 3-hydroxybutyryl-CoA dehydratase 1203927 1150541 LA_1198 Leptospira interrogans serovar Lai str. 56601 3-hydroxybutyryl-CoA dehydratase NP_711379.1 1203154 D 189518 CDS NP_711381.2 294827815 1150543 1204242..1204712 1 NC_004342.2 hypothetical protein 1204712 1150543 LA_1200 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711381.2 1204242 D 189518 CDS NP_711382.2 294827816 1150544 complement(1204813..1205418) 1 NC_004342.2 hypothetical protein 1205418 1150544 LA_1202 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711382.2 1204813 R 189518 CDS NP_711384.1 24213903 1150546 1205595..1207049 1 NC_004342.2 MBOAT family D-alaninealginate export/acetyltransferase membrane protein 1207049 dltB 1150546 dltB Leptospira interrogans serovar Lai str. 56601 MBOAT family D-alaninealginate export/acetyltransferase membrane protein NP_711384.1 1205595 D 189518 CDS NP_711385.1 24213904 1150547 1207182..1207541 1 NC_004342.2 hypothetical protein 1207541 1150547 LA_1204 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711385.1 1207182 D 189518 CDS NP_711386.1 24213905 1150548 1207605..1208225 1 NC_004342.2 RNA polymerase ECF-type sigma factor 1208225 rpoE 1150548 rpoE Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_711386.1 1207605 D 189518 CDS NP_711387.1 24213906 1150549 1208206..1208793 1 NC_004342.2 hypothetical protein 1208793 1150549 LA_1206 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711387.1 1208206 D 189518 CDS NP_711388.1 24213907 1150550 1209484..1209906 1 NC_004342.2 thioesterase superfamily protein 1209906 1150550 LA_1207 Leptospira interrogans serovar Lai str. 56601 thioesterase superfamily protein NP_711388.1 1209484 D 189518 CDS NP_711390.1 24213909 1150552 1210066..1211424 1 NC_004342.2 hypothetical protein 1211424 1150552 LA_1209 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711390.1 1210066 D 189518 CDS NP_711391.2 294827817 1150553 complement(1211411..1212130) 1 NC_004342.2 integral membrane protein TerC 1212130 terC 1150553 terC Leptospira interrogans serovar Lai str. 56601 integral membrane protein TerC NP_711391.2 1211411 R 189518 CDS NP_711392.1 24213911 1150554 1212206..1212769 1 NC_004342.2 peroxiredoxin-like protein 1212769 1150554 LA_1210 Leptospira interrogans serovar Lai str. 56601 peroxiredoxin-like protein NP_711392.1 1212206 D 189518 CDS NP_711393.2 294827818 1150555 complement(1212770..1213204) 1 NC_004342.2 hypothetical protein 1213204 uspA 1150555 uspA Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711393.2 1212770 R 189518 CDS NP_711394.1 24213913 1150556 1213363..1214193 1 NC_004342.2 hypothetical protein 1214193 1150556 LA_1213 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711394.1 1213363 D 189518 CDS NP_711395.1 24213914 1150557 1215473..1217275 1 NC_004342.2 methyl-accepting chemotaxis protein 1217275 1150557 LA_1214 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_711395.1 1215473 D 189518 CDS NP_711398.1 24213917 1150560 complement(1218475..1219080) 1 NC_004342.2 acetyltransferase 1219080 1150560 LA_1217 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_711398.1 1218475 R 189518 CDS NP_711400.2 294827819 1150562 complement(1219811..1220629) 1 NC_004342.2 intramembrane serine protease 1220629 glpG 1150562 glpG Leptospira interrogans serovar Lai str. 56601 intramembrane serine protease NP_711400.2 1219811 R 189518 CDS NP_711401.1 24213920 1150563 1220736..1221692 1 NC_004342.2 metal-dependent hydrolase 1221692 1150563 LA_1220 Leptospira interrogans serovar Lai str. 56601 metal-dependent hydrolase NP_711401.1 1220736 D 189518 CDS NP_711402.1 24213921 1150564 1221689..1224127 1 NC_004342.2 membrane carboxypeptidase/penicillin-binding protein 1224127 mrcA 1150564 mrcA Leptospira interrogans serovar Lai str. 56601 membrane carboxypeptidase/penicillin-binding protein NP_711402.1 1221689 D 189518 CDS NP_711403.1 24213922 1150565 1224215..1225474 1 NC_004342.2 dihydrolipoamide acetyltransferase 1225474 aceF 1150565 aceF Leptospira interrogans serovar Lai str. 56601 dihydrolipoamide acetyltransferase NP_711403.1 1224215 D 189518 CDS NP_711404.1 24213923 1150566 1225488..1226891 1 NC_004342.2 dihydrolipoamide dehydrogenase 1226891 lpd 1150566 lpd Leptospira interrogans serovar Lai str. 56601 dihydrolipoamide dehydrogenase NP_711404.1 1225488 D 189518 CDS NP_711405.1 24213924 1150567 1226915..1229677 1 NC_004342.2 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1229677 sucA 1150567 sucA Leptospira interrogans serovar Lai str. 56601 2-oxoglutarate dehydrogenase E1 NP_711405.1 1226915 D 189518 CDS NP_711406.2 294827820 1150568 1229944..1230147 1 NC_004342.2 hypothetical protein 1230147 1150568 LA_1225 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711406.2 1229944 D 189518 CDS NP_711407.2 294827821 1150569 1230304..1230537 1 NC_004342.2 acetyltransferase 1230537 1150569 LA_1226 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_711407.2 1230304 D 189518 CDS NP_711409.1 24213928 1150571 1231014..1231586 1 NC_004342.2 hypothetical protein 1231586 1150571 LA_1228 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711409.1 1231014 D 189518 CDS NP_711411.1 24213930 1150573 complement(1232328..1233443) 1 NC_004342.2 hypothetical protein 1233443 1150573 LA_1230 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711411.1 1232328 R 189518 CDS NP_711412.1 24213931 1150574 complement(1233440..1235251) 1 NC_004342.2 HSP90 family protein 1235251 1150574 LA_1231 Leptospira interrogans serovar Lai str. 56601 HSP90 family protein NP_711412.1 1233440 R 189518 CDS NP_711414.2 294827822 1150576 complement(1235944..1237113) 1 NC_004342.2 ISlin1 transposase 1237113 1150576 LA_1233 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_711414.2 1235944 R 189518 CDS NP_711419.1 24213938 1150581 complement(1241025..1241213) 1 NC_004342.2 hypothetical protein 1241213 1150581 LA_1238 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711419.1 1241025 R 189518 CDS NP_711420.2 294827823 1150582 complement(1241219..1242307) 1 NC_004342.2 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1242307 carA 1150582 carA Leptospira interrogans serovar Lai str. 56601 carbamoyl phosphate synthase small subunit NP_711420.2 1241219 R 189518 CDS NP_711421.1 24213940 1150583 1242561..1244477 1 NC_004342.2 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1244477 thrS 1150583 thrS Leptospira interrogans serovar Lai str. 56601 threonyl-tRNA synthetase NP_711421.1 1242561 D 189518 CDS NP_711422.1 24213941 1150584 complement(1244566..1244772) 1 NC_004342.2 hypothetical protein 1244772 1150584 LA_1241 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711422.1 1244566 R 189518 CDS YP_003573305.1 294827824 9006897 complement(1244776..1245108) 1 NC_004342.2 hypothetical protein 1245108 9006897 LA_1241a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573305.1 1244776 R 189518 CDS NP_711423.1 24213942 1150585 1245962..1246501 1 NC_004342.2 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1246501 infC 1150585 infC Leptospira interrogans serovar Lai str. 56601 translation initiation factor IF-3 NP_711423.1 1245962 D 189518 CDS NP_711424.1 24213943 1150586 1246534..1246737 1 NC_004342.2 50S ribosomal protein L35 1246737 rpmI 1150586 rpmI Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L35 NP_711424.1 1246534 D 189518 CDS NP_711425.1 24213944 1150587 1246737..1247090 1 NC_004342.2 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1247090 rplT 1150587 rplT Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L20 NP_711425.1 1246737 D 189518 CDS NP_711426.1 24213945 1150588 1247178..1247816 1 NC_004342.2 hypothetical protein 1247816 1150588 LA_1245 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711426.1 1247178 D 189518 CDS NP_711427.2 294827825 1150589 1247824..1248141 1 NC_004342.2 cell division protein ZapA 1248141 zapA 1150589 zapA Leptospira interrogans serovar Lai str. 56601 cell division protein ZapA NP_711427.2 1247824 D 189518 CDS NP_711428.1 24213947 1150590 1248171..1248701 1 NC_004342.2 5-formyltetrahydrofolate cyclo-ligase 1248701 1150590 LA_1247 Leptospira interrogans serovar Lai str. 56601 5-formyltetrahydrofolate cyclo-ligase NP_711428.1 1248171 D 189518 CDS NP_711431.2 294827826 1150593 1249310..1249804 1 NC_004342.2 chemotaxis protein CheW 1249804 cheW 1150593 cheW Leptospira interrogans serovar Lai str. 56601 chemotaxis protein CheW NP_711431.2 1249310 D 189518 CDS NP_711432.1 24213951 1150594 1249804..1253016 1 NC_004342.2 chemotaxis protein histidine kinase CheA 1253016 cheA 1150594 cheA Leptospira interrogans serovar Lai str. 56601 chemotaxis protein histidine kinase CheA NP_711432.1 1249804 D 189518 CDS NP_711433.1 24213952 1150595 1253022..1254095 1 NC_004342.2 chemotaxis-specific methylesterase CheB 1254095 cheB 1150595 cheB Leptospira interrogans serovar Lai str. 56601 chemotaxis-specific methylesterase CheB NP_711433.1 1253022 D 189518 CDS NP_711434.1 24213953 1150596 1254097..1254459 1 NC_004342.2 two-component response regulator receiver protein 1254459 1150596 LA_1253 Leptospira interrogans serovar Lai str. 56601 two-component response regulator receiver protein NP_711434.1 1254097 D 189518 CDS NP_711435.1 24213954 1150597 1254477..1255262 1 NC_004342.2 segregation and condensation protein A 1255262 scpA 1150597 scpA Leptospira interrogans serovar Lai str. 56601 segregation and condensation protein A NP_711435.1 1254477 D 189518 CDS NP_711436.1 24213955 1150598 1255229..1255792 1 NC_004342.2 segregation and condensation protein B 1255792 scpB 1150598 scpB Leptospira interrogans serovar Lai str. 56601 segregation and condensation protein B NP_711436.1 1255229 D 189518 CDS NP_711437.2 294827827 1150599 1255785..1256876 1 NC_004342.2 bifunctional prephenate dehydratase/chorismate mutase 1256876 pheA 1150599 pheA Leptospira interrogans serovar Lai str. 56601 bifunctional prephenate dehydratase/chorismate mutase NP_711437.2 1255785 D 189518 CDS NP_711438.1 24213957 1150600 1256873..1257790 1 NC_004342.2 bifunctional prephenate dehydrogenase/chorismate mutase 1257790 tyrA 1150600 tyrA Leptospira interrogans serovar Lai str. 56601 bifunctional prephenate dehydrogenase/chorismate mutase NP_711438.1 1256873 D 189518 CDS NP_711439.1 24213958 1150601 1257771..1259093 1 NC_004342.2 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1259093 aroA 1150601 aroA Leptospira interrogans serovar Lai str. 56601 3-phosphoshikimate 1-carboxyvinyltransferase NP_711439.1 1257771 D 189518 CDS NP_711440.2 294827828 1150602 1259086..1259775 1 NC_004342.2 cytidylate kinase 1259775 cmk 1150602 cmk Leptospira interrogans serovar Lai str. 56601 cytidylate kinase NP_711440.2 1259086 D 189518 CDS NP_711441.1 24213960 1150603 1259828..1261510 1 NC_004342.2 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1261510 rpsA 1150603 rpsA Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S1 NP_711441.1 1259828 D 189518 CDS NP_711442.1 24213961 1150604 1261535..1262278 1 NC_004342.2 hypothetical protein 1262278 1150604 LA_1261 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711442.1 1261535 D 189518 CDS NP_711443.2 294827829 1150605 1262278..1262895 1 NC_004342.2 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 1262895 hisG 1150605 hisG Leptospira interrogans serovar Lai str. 56601 ATP phosphoribosyltransferase NP_711443.2 1262278 D 189518 CDS NP_711444.1 24213963 1150606 1263192..1263392 1 NC_004342.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1263392 rpmF 1150606 rpmF Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L32 NP_711444.1 1263192 D 189518 CDS NP_711445.1 24213964 1150607 1263398..1264405 1 NC_004342.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1264405 plsX 1150607 plsX Leptospira interrogans serovar Lai str. 56601 glycerol-3-phosphate acyltransferase PlsX NP_711445.1 1263398 D 189518 CDS NP_711452.1 24213971 1150614 1266243..1266449 1 NC_004342.2 hypothetical protein 1266449 1150614 LA_1271 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711452.1 1266243 D 189518 CDS NP_711453.2 294827830 1150615 complement(1266644..1267090) 1 NC_004342.2 transcriptional regulator 1267090 1150615 LA_1272 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711453.2 1266644 R 189518 CDS NP_711454.1 24213973 1150616 complement(1268112..1268612) 1 NC_004342.2 hypothetical protein 1268612 1150616 LA_1273 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711454.1 1268112 R 189518 CDS NP_711456.1 24213975 1150618 1268949..1269065 1 NC_004342.2 hypothetical protein 1269065 1150618 LA_1275 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711456.1 1268949 D 189518 CDS NP_711457.1 24213976 1150619 1269211..1271124 1 NC_004342.2 sulfatase 1271124 1150619 LA_1276 Leptospira interrogans serovar Lai str. 56601 sulfatase NP_711457.1 1269211 D 189518 CDS NP_711461.1 24213980 1150623 complement(1272574..1274562) 1 NC_004342.2 phosphoglycerol transferase-like protein 1274562 1150623 LA_1280 Leptospira interrogans serovar Lai str. 56601 phosphoglycerol transferase-like protein NP_711461.1 1272574 R 189518 CDS NP_711463.1 24213982 1150625 1275183..1275938 1 NC_004342.2 transcriptional regulator 1275938 1150625 LA_1282 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711463.1 1275183 D 189518 CDS NP_711464.1 24213983 1150626 1275969..1276784 1 NC_004342.2 hypothetical protein 1276784 1150626 LA_1283 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711464.1 1275969 D 189518 CDS NP_711465.1 24213984 1150627 1276784..1278022 1 NC_004342.2 lipoprotein releasing system permease 1278022 lolE 1150627 lolE Leptospira interrogans serovar Lai str. 56601 lipoprotein releasing system permease NP_711465.1 1276784 D 189518 CDS NP_711466.2 294827831 1150628 1278024..1278737 1 NC_004342.2 antimicrobial peptide ABC transporter ATPase 1278737 salX 1150628 salX Leptospira interrogans serovar Lai str. 56601 antimicrobial peptide ABC transporter ATPase NP_711466.2 1278024 D 189518 CDS NP_711467.2 294827832 1150629 1278801..1280018 1 NC_004342.2 hypothetical protein 1280018 1150629 LA_1286 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711467.2 1278801 D 189518 CDS NP_711470.2 294827833 1150632 1280639..1280860 1 NC_004342.2 hypothetical protein 1280860 1150632 LA_1289 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711470.2 1280639 D 189518 CDS NP_711471.1 24213990 1150633 complement(1281300..1281719) 1 NC_004342.2 hypothetical protein 1281719 1150633 LA_1290 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711471.1 1281300 R 189518 CDS NP_711472.1 24213991 1150634 complement(1281676..1282287) 1 NC_004342.2 hypothetical protein 1282287 1150634 LA_1291 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711472.1 1281676 R 189518 CDS NP_711473.1 24213992 1150635 complement(1282789..1283640) 1 NC_004342.2 prepilin leader peptidase 1283640 1150635 LA_1292 Leptospira interrogans serovar Lai str. 56601 prepilin leader peptidase NP_711473.1 1282789 R 189518 CDS NP_711474.1 24213993 1150636 complement(1283624..1284724) 1 NC_004342.2 aspartate/tyrosine/aromatic aminotransferase 1284724 1150636 LA_1293 Leptospira interrogans serovar Lai str. 56601 aspartate/tyrosine/aromatic aminotransferase NP_711474.1 1283624 R 189518 CDS NP_711476.2 294827834 1150638 1285904..1288936 1 NC_004342.2 hypothetical protein 1288936 1150638 LA_1295 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711476.2 1285904 D 189518 CDS NP_711478.1 24213997 1150640 1289480..1290058 1 NC_004342.2 hypothetical protein 1290058 1150640 LA_1297 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711478.1 1289480 D 189518 CDS NP_711480.2 294827835 1150642 complement(1290446..1292884) 1 NC_004342.2 ankyrin repeat-containing protein 1292884 1150642 LA_1299 Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_711480.2 1290446 R 189518 CDS NP_711483.1 24214002 1150645 1293454..1293936 1 NC_004342.2 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1293936 smpB 1150645 smpB Leptospira interrogans serovar Lai str. 56601 SsrA-binding protein NP_711483.1 1293454 D 189518 CDS NP_711484.1 24214003 1150646 1293961..1295430 1 NC_004342.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1295430 engA 1150646 engA Leptospira interrogans serovar Lai str. 56601 GTP-binding protein EngA NP_711484.1 1293961 D 189518 CDS NP_711485.1 24214004 1150647 1295427..1296077 1 NC_004342.2 membrane protein 1296077 1150647 LA_1304 Leptospira interrogans serovar Lai str. 56601 membrane protein NP_711485.1 1295427 D 189518 CDS NP_711486.1 24214005 1150648 1296052..1296852 1 NC_004342.2 hypothetical protein 1296852 1150648 LA_1305 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711486.1 1296052 D 189518 CDS NP_711487.1 24214006 1150649 1296941..1297153 1 NC_004342.2 hypothetical protein 1297153 1150649 LA_1306 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711487.1 1296941 D 189518 CDS NP_711488.1 24214007 1150650 complement(1298711..1300540) 1 NC_004342.2 hypothetical protein 1300540 1150650 LA_1307 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711488.1 1298711 R 189518 CDS NP_711490.2 294827836 1150652 1300631..1303405 1 NC_004342.2 chromosome segregation protein 1303405 smc 1150652 smc Leptospira interrogans serovar Lai str. 56601 chromosome segregation protein NP_711490.2 1300631 D 189518 CDS NP_711491.1 24214010 1150653 complement(1303528..1304058) 1 NC_004342.2 hypothetical protein 1304058 1150653 LA_1310 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711491.1 1303528 R 189518 CDS NP_711493.2 294827837 1150655 complement(1304625..1304909) 1 NC_004342.2 hypothetical protein 1304909 1150655 LA_1312 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711493.2 1304625 R 189518 CDS YP_003573306.1 294827838 9006899 complement(1305066..1306361) 1 NC_004342.2 hypothetical protein 1306361 9006899 LA_1312a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573306.1 1305066 R 189518 CDS NP_711494.1 24214013 1150656 1306687..1308108 1 NC_004342.2 glutamine synthetase 1308108 glnA 1150656 glnA Leptospira interrogans serovar Lai str. 56601 glutamine synthetase NP_711494.1 1306687 D 189518 CDS NP_711498.2 294827839 1150660 1308900..1309442 1 NC_004342.2 hypothetical protein 1309442 1150660 LA_1317 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711498.2 1308900 D 189518 CDS NP_711500.1 24214019 1150662 complement(1309759..1310472) 1 NC_004342.2 hypothetical protein 1310472 1150662 LA_1319 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711500.1 1309759 R 189518 CDS NP_711502.2 294827840 1150664 1311659..1312954 1 NC_004342.2 disulfide interchange transmembrane protein 1312954 1150664 LA_1321 Leptospira interrogans serovar Lai str. 56601 disulfide interchange transmembrane protein NP_711502.2 1311659 D 189518 CDS NP_711504.1 24214023 1150666 1314311..1316548 1 NC_004342.2 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1316548 purL 1150666 purL Leptospira interrogans serovar Lai str. 56601 phosphoribosylformylglycinamidine synthase II NP_711504.1 1314311 D 189518 CDS NP_711505.1 24214024 1150667 1316564..1317217 1 NC_004342.2 hypothetical protein 1317217 1150667 LA_1324 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711505.1 1316564 D 189518 CDS NP_711506.1 24214025 1150668 1317225..1319969 1 NC_004342.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1319969 ileS 1150668 ileS Leptospira interrogans serovar Lai str. 56601 isoleucyl-tRNA synthetase NP_711506.1 1317225 D 189518 CDS NP_711507.1 24214026 1150669 complement(1320348..1321088) 1 NC_004342.2 hypothetical protein 1321088 1150669 LA_1326 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711507.1 1320348 R 189518 CDS NP_711508.2 294827841 1150670 complement(1321085..1321453) 1 NC_004342.2 anti-sigma factor antagonist 1321453 1150670 LA_1327 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_711508.2 1321085 R 189518 CDS NP_711509.2 294827842 1150671 1321566..1323404 1 NC_004342.2 hypothetical protein 1323404 1150671 LA_1328 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711509.2 1321566 D 189518 CDS NP_711510.1 24214029 1150672 1323420..1324139 1 NC_004342.2 hypothetical protein 1324139 1150672 LA_1329 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711510.1 1323420 D 189518 CDS NP_711511.1 24214030 1150673 1324136..1324606 1 NC_004342.2 hypothetical protein 1324606 1150673 LA_1330 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711511.1 1324136 D 189518 CDS NP_711512.1 24214031 1150674 1324736..1324924 1 NC_004342.2 hypothetical protein 1324924 1150674 LA_1331 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711512.1 1324736 D 189518 CDS NP_711513.2 294827843 1150675 complement(1325669..1326631) 1 NC_004342.2 ankyrin repeat-containing protein 1326631 1150675 LA_1332 Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_711513.2 1325669 R 189518 CDS NP_711514.2 294827844 1150676 1326785..1328269 1 NC_004342.2 amidase 1328269 gatA 1150676 gatA Leptospira interrogans serovar Lai str. 56601 amidase NP_711514.2 1326785 D 189518 CDS NP_711515.1 24214034 1150677 1329237..1330406 1 NC_004342.2 oxidoreductase 1330406 1150677 LA_1334 Leptospira interrogans serovar Lai str. 56601 oxidoreductase NP_711515.1 1329237 D 189518 CDS NP_711516.1 24214035 1150678 1330418..1332130 1 NC_004342.2 protein kinase 1332130 aarF 1150678 aarF Leptospira interrogans serovar Lai str. 56601 protein kinase NP_711516.1 1330418 D 189518 CDS NP_711517.1 24214036 1150679 1332127..1332675 1 NC_004342.2 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1332675 1150679 LA_1336 Leptospira interrogans serovar Lai str. 56601 lipoprotein signal peptidase NP_711517.1 1332127 D 189518 CDS NP_711518.1 24214037 1150680 1332680..1333207 1 NC_004342.2 cAMP-binding protein 1333207 crp 1150680 crp Leptospira interrogans serovar Lai str. 56601 cAMP-binding protein NP_711518.1 1332680 D 189518 CDS NP_711519.1 24214038 1150681 1333200..1334267 1 NC_004342.2 permease 1334267 perM 1150681 perM Leptospira interrogans serovar Lai str. 56601 permease NP_711519.1 1333200 D 189518 CDS NP_711520.1 24214039 1150682 complement(1334997..1335926) 1 NC_004342.2 permease 1335926 1150682 LA_1339 Leptospira interrogans serovar Lai str. 56601 permease NP_711520.1 1334997 R 189518 CDS NP_711521.2 294827845 1150683 complement(1336235..1337047) 1 NC_004342.2 sodium bile acid symporter 1337047 1150683 LA_1340 Leptospira interrogans serovar Lai str. 56601 sodium bile acid symporter NP_711521.2 1336235 R 189518 CDS NP_711524.2 294827846 1150686 1337912..1338619 1 NC_004342.2 hypothetical protein 1338619 1150686 LA_1343 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711524.2 1337912 D 189518 CDS NP_711526.2 294827847 1150688 complement(1338952..1340811) 1 NC_004342.2 hypothetical protein 1340811 1150688 LA_1345 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711526.2 1338952 R 189518 CDS NP_711528.2 294827848 1150690 complement(1341051..1341506) 1 NC_004342.2 two-component system signal receiver 1341506 1150690 LA_1347 Leptospira interrogans serovar Lai str. 56601 two-component system signal receiver NP_711528.2 1341051 R 189518 CDS NP_711529.1 24214048 1150691 complement(1341499..1342887) 1 NC_004342.2 histidine kinase sensor protein 1342887 1150691 LA_1348 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_711529.1 1341499 R 189518 CDS NP_711530.2 294827849 1150692 1343519..1343710 1 NC_004342.2 hypothetical protein 1343710 1150692 LA_1349 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711530.2 1343519 D 189518 CDS NP_711531.2 294827850 1150693 complement(1343770..1344633) 1 NC_004342.2 3-demethylubiquinone-9 3-methyltransferase 1344633 1150693 LA_1350 Leptospira interrogans serovar Lai str. 56601 3-demethylubiquinone-9 3-methyltransferase NP_711531.2 1343770 R 189518 CDS NP_711532.1 24214051 1150694 1344720..1345748 1 NC_004342.2 capsule biosynthesis protein CapA 1345748 1150694 LA_1351 Leptospira interrogans serovar Lai str. 56601 capsule biosynthesis protein CapA NP_711532.1 1344720 D 189518 CDS NP_711534.2 294827851 1150696 1346788..1347312 1 NC_004342.2 cytoplasmic membrane protein 1347312 1150696 LA_1353 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_711534.2 1346788 D 189518 CDS NP_711535.1 24214054 1150697 1347387..1347686 1 NC_004342.2 cytoplasmic membrane protein 1347686 1150697 LA_1354 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_711535.1 1347387 D 189518 CDS NP_711537.2 294827852 1150699 1348281..1350392 1 NC_004342.2 TonB-dependent outer membrane receptor 1350392 1150699 LA_1356 Leptospira interrogans serovar Lai str. 56601 TonB-dependent outer membrane receptor NP_711537.2 1348281 D 189518 CDS NP_711538.1 24214057 1150700 1350394..1351557 1 NC_004342.2 hypothetical protein 1351557 1150700 LA_1357 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711538.1 1350394 D 189518 CDS NP_711539.1 24214058 1150701 1352181..1352837 1 NC_004342.2 ankyrin repeat-containing protein 1352837 arp 1150701 arp Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_711539.1 1352181 D 189518 CDS NP_711540.1 24214059 1150702 1353315..1353767 1 NC_004342.2 hypothetical protein 1353767 1150702 LA_1359 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711540.1 1353315 D 189518 CDS NP_711542.2 294827853 1150704 1354731..1355900 1 NC_004342.2 ISlin1 transposase 1355900 1150704 LA_1361 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_711542.2 1354731 D 189518 CDS NP_711543.1 24214062 1150705 1356120..1356635 1 NC_004342.2 hypothetical protein 1356635 1150705 LA_1362 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711543.1 1356120 D 189518 CDS NP_711544.2 294827854 1150706 1356830..1358005 1 NC_004342.2 transcriptional regulator 1358005 1150706 LA_1363 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711544.2 1356830 D 189518 CDS NP_711545.1 24214064 1150707 1358012..1358383 1 NC_004342.2 hypothetical protein 1358383 1150707 LA_1364 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711545.1 1358012 D 189518 CDS NP_711546.1 24214065 1150708 1358419..1359951 1 NC_004342.2 MBOAT family D-alaninealginate export/acetyltransferase membrane protein 1359951 dltB 1150708 dltB Leptospira interrogans serovar Lai str. 56601 MBOAT family D-alaninealginate export/acetyltransferase membrane protein NP_711546.1 1358419 D 189518 CDS NP_711547.2 294827855 1150709 1359929..1361134 1 NC_004342.2 hypothetical protein 1361134 1150709 LA_1366 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711547.2 1359929 D 189518 CDS NP_711549.1 24214068 1150711 complement(1361713..1363704) 1 NC_004342.2 hypothetical protein 1363704 1150711 LA_1368 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711549.1 1361713 R 189518 CDS NP_711550.1 24214069 1150712 1363894..1364451 1 NC_004342.2 TlpA-like protein 1364451 1150712 LA_1369 Leptospira interrogans serovar Lai str. 56601 TlpA-like protein NP_711550.1 1363894 D 189518 CDS NP_711551.1 24214070 1150713 complement(1364454..1365095) 1 NC_004342.2 3-methyl-adenine DNA glycosylase 1365095 alkA 1150713 alkA Leptospira interrogans serovar Lai str. 56601 3-methyl-adenine DNA glycosylase NP_711551.1 1364454 R 189518 CDS NP_711553.1 24214072 1150715 1365267..1366496 1 NC_004342.2 permease 1366496 1150715 LA_1372 Leptospira interrogans serovar Lai str. 56601 permease NP_711553.1 1365267 D 189518 CDS NP_711555.2 294827856 1150717 1367502..1368359 1 NC_004342.2 pirin 1368359 1150717 LA_1374 Leptospira interrogans serovar Lai str. 56601 pirin NP_711555.2 1367502 D 189518 CDS NP_711556.1 24214075 1150718 complement(1368621..1369943) 1 NC_004342.2 hypothetical protein 1369943 1150718 LA_1375 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711556.1 1368621 R 189518 CDS NP_711558.2 294827857 1150720 complement(1370824..1371237) 1 NC_004342.2 hypothetical protein 1371237 1150720 LA_1377 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711558.2 1370824 R 189518 CDS NP_711559.1 24214078 1150721 1372006..1373826 1 NC_004342.2 GTP-binding protein BipA 1373826 bipA 1150721 bipA Leptospira interrogans serovar Lai str. 56601 GTP-binding protein BipA NP_711559.1 1372006 D 189518 CDS NP_711563.1 24214082 1150725 1375123..1376334 1 NC_004342.2 acetyltransferase 1376334 1150725 LA_1382 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_711563.1 1375123 D 189518 CDS NP_711564.1 24214083 1150726 1376688..1377869 1 NC_004342.2 transcriptional regulator 1377869 1150726 LA_1383 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711564.1 1376688 D 189518 CDS NP_711565.1 24214084 1150727 complement(1378754..1379674) 1 NC_004342.2 hypothetical protein 1379674 1150727 LA_1384 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711565.1 1378754 R 189518 CDS NP_711566.1 24214085 1150728 complement(1379834..1380292) 1 NC_004342.2 hypothetical protein 1380292 1150728 LA_1385 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711566.1 1379834 R 189518 CDS NP_711569.1 24214088 1150731 complement(1381518..1382912) 1 NC_004342.2 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1382912 grs1 1150731 grs1 Leptospira interrogans serovar Lai str. 56601 glycyl-tRNA synthetase NP_711569.1 1381518 R 189518 CDS NP_711570.2 294827858 1150732 1383079..1384701 1 NC_004342.2 hypothetical protein 1384701 1150732 LA_1389 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711570.2 1383079 D 189518 CDS NP_711571.1 24214090 1150733 1384698..1385450 1 NC_004342.2 hypothetical protein 1385450 1150733 LA_1390 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711571.1 1384698 D 189518 CDS NP_711572.1 24214091 1150734 1385447..1386349 1 NC_004342.2 ribosomal protein L11 methylase 1386349 prmA 1150734 prmA Leptospira interrogans serovar Lai str. 56601 ribosomal protein L11 methylase NP_711572.1 1385447 D 189518 CDS NP_711573.1 24214092 1150735 1386354..1387340 1 NC_004342.2 ribokinase 1387340 rbsK 1150735 rbsK Leptospira interrogans serovar Lai str. 56601 ribokinase NP_711573.1 1386354 D 189518 CDS NP_711574.1 24214093 1150736 complement(1388429..1388800) 1 NC_004342.2 hypothetical protein 1388800 1150736 LA_1393 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711574.1 1388429 R 189518 CDS NP_711577.2 294827859 1150739 complement(1389405..1389938) 1 NC_004342.2 hypothetical protein 1389938 1150739 LA_1396 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711577.2 1389405 R 189518 CDS NP_711578.1 24214097 1150740 complement(1389997..1392951) 1 NC_004342.2 export protein 1392951 1150740 LA_1397 Leptospira interrogans serovar Lai str. 56601 export protein NP_711578.1 1389997 R 189518 CDS NP_711579.1 24214098 1150741 complement(1392958..1393614) 1 NC_004342.2 hypothetical protein 1393614 1150741 LA_1398 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711579.1 1392958 R 189518 CDS NP_711581.2 294827860 1150743 1395850..1397571 1 NC_004342.2 hypothetical protein 1397571 1150743 LA_1400 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711581.2 1395850 D 189518 CDS NP_711583.2 294827861 1150745 1398555..1400480 1 NC_004342.2 hypothetical protein 1400480 1150745 LA_1402 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711583.2 1398555 D 189518 CDS NP_711584.2 294827862 1150746 1402601..1402801 1 NC_004342.2 hypothetical protein 1402801 1150746 LA_1403 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711584.2 1402601 D 189518 CDS NP_711585.2 294827863 1150747 1402813..1403985 1 NC_004342.2 hypothetical protein 1403985 1150747 LA_1404 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711585.2 1402813 D 189518 CDS NP_711587.1 24214106 1150749 complement(1405088..1406416) 1 NC_004342.2 sterol desaturase 1406416 erg3 1150749 erg3 Leptospira interrogans serovar Lai str. 56601 sterol desaturase NP_711587.1 1405088 R 189518 CDS YP_003573307.1 294827864 9006900 1406639..1406821 1 NC_004342.2 hypothetical protein 1406821 9006900 LA_1406a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573307.1 1406639 D 189518 CDS NP_711590.1 24214109 1150752 complement(1407320..1408567) 1 NC_004342.2 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1408567 glyA 1150752 glyA Leptospira interrogans serovar Lai str. 56601 serine hydroxymethyltransferase NP_711590.1 1407320 R 189518 CDS NP_711591.1 24214110 1150753 complement(1408607..1409593) 1 NC_004342.2 lipoate protein ligase A 1409593 lplA 1150753 lplA Leptospira interrogans serovar Lai str. 56601 lipoate protein ligase A NP_711591.1 1408607 R 189518 CDS NP_711593.2 294827865 1150755 complement(1410480..1411484) 1 NC_004342.2 hypothetical protein 1411484 1150755 LA_1412 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711593.2 1410480 R 189518 CDS NP_711595.1 24214114 1150757 1411615..1412697 1 NC_004342.2 hypothetical protein 1412697 1150757 LA_1413 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711595.1 1411615 D 189518 CDS NP_711597.1 24214116 1150759 1413393..1414238 1 NC_004342.2 2-methylisocitrate lyase 1414238 prpB 1150759 prpB Leptospira interrogans serovar Lai str. 56601 2-methylisocitrate lyase NP_711597.1 1413393 D 189518 CDS NP_711598.1 24214117 1150760 1414608..1415066 1 NC_004342.2 lactoylglutathione lyase 1415066 1150760 LA_1417 Leptospira interrogans serovar Lai str. 56601 lactoylglutathione lyase NP_711598.1 1414608 D 189518 CDS NP_711600.2 294827866 1150762 complement(1416034..1417494) 1 NC_004342.2 guanylate cyclase 1417494 cyaA 1150762 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_711600.2 1416034 R 189518 CDS NP_711601.1 24214120 1150763 complement(1417519..1417893) 1 NC_004342.2 hypothetical protein 1417893 1150763 LA_1420 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711601.1 1417519 R 189518 CDS NP_711602.1 24214121 1150764 complement(1417896..1418450) 1 NC_004342.2 hypothetical protein 1418450 1150764 LA_1421 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711602.1 1417896 R 189518 CDS NP_711603.1 24214122 1150765 complement(1418488..1423830) 1 NC_004342.2 serine/threonine kinase 1423830 1150765 LA_1422 Leptospira interrogans serovar Lai str. 56601 serine/threonine kinase NP_711603.1 1418488 R 189518 CDS NP_711604.1 24214123 1150766 complement(1423855..1424823) 1 NC_004342.2 3-oxoacyl-ACP synthase 1424823 fabH 1150766 fabH Leptospira interrogans serovar Lai str. 56601 3-oxoacyl-ACP synthase NP_711604.1 1423855 R 189518 CDS NP_711605.1 24214124 1150767 complement(1424857..1426638) 1 NC_004342.2 3-oxoacid CoA-transferase 1426638 1150767 LA_1424 Leptospira interrogans serovar Lai str. 56601 3-oxoacid CoA-transferase NP_711605.1 1424857 R 189518 CDS NP_711606.2 294827867 1150768 1427067..1427921 1 NC_004342.2 thioesterase 1427921 1150768 LA_1425 Leptospira interrogans serovar Lai str. 56601 thioesterase NP_711606.2 1427067 D 189518 CDS NP_711608.2 294827868 1150770 1428288..1429046 1 NC_004342.2 short chain dehydrogenase 1429046 fabG 1150770 fabG Leptospira interrogans serovar Lai str. 56601 short chain dehydrogenase NP_711608.2 1428288 D 189518 CDS NP_711609.1 24214128 1150771 1429744..1430553 1 NC_004342.2 serine/threonine phosphatase 1430553 ptc1 1150771 ptc1 Leptospira interrogans serovar Lai str. 56601 serine/threonine phosphatase NP_711609.1 1429744 D 189518 CDS NP_711610.1 24214129 1150772 complement(1430528..1431055) 1 NC_004342.2 hypothetical protein 1431055 1150772 LA_1429 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711610.1 1430528 R 189518 CDS NP_711611.2 294827869 1150773 complement(1431066..1432355) 1 NC_004342.2 beta-ketoacyl synthase 1432355 fabB 1150773 fabB Leptospira interrogans serovar Lai str. 56601 beta-ketoacyl synthase NP_711611.2 1431066 R 189518 CDS NP_711613.2 294827870 1150775 complement(1433706..1434116) 1 NC_004342.2 two-component response regulator receiver protein 1434116 1150775 LA_1432 Leptospira interrogans serovar Lai str. 56601 two-component response regulator receiver protein NP_711613.2 1433706 R 189518 CDS NP_711614.1 24214133 1150776 complement(1434416..1435729) 1 NC_004342.2 hypothetical protein 1435729 1150776 LA_1433 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711614.1 1434416 R 189518 CDS NP_711616.2 294827871 1150778 complement(1437425..1438435) 1 NC_004342.2 hypothetical protein 1438435 1150778 LA_1435 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711616.2 1437425 R 189518 CDS NP_711617.2 294827872 1150779 complement(1438452..1438802) 1 NC_004342.2 HIT family hydrolase 1438802 hit 1150779 hit Leptospira interrogans serovar Lai str. 56601 HIT family hydrolase NP_711617.2 1438452 R 189518 CDS NP_711618.1 24214137 1150780 complement(1438799..1439695) 1 NC_004342.2 glucose kinase 1439695 nagC 1150780 nagC Leptospira interrogans serovar Lai str. 56601 glucose kinase NP_711618.1 1438799 R 189518 CDS NP_711619.1 24214138 1150781 complement(1439692..1440357) 1 NC_004342.2 antimicrobial peptide ABC transporter ATPase 1440357 salX 1150781 salX Leptospira interrogans serovar Lai str. 56601 antimicrobial peptide ABC transporter ATPase NP_711619.1 1439692 R 189518 CDS NP_711620.1 24214139 1150782 complement(1440354..1440878) 1 NC_004342.2 hypothetical protein 1440878 1150782 LA_1439 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711620.1 1440354 R 189518 CDS NP_711621.1 24214140 1150783 1440993..1442552 1 NC_004342.2 hypothetical protein 1442552 1150783 LA_1440 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711621.1 1440993 D 189518 CDS NP_711622.2 294827873 1150784 complement(1442931..1444100) 1 NC_004342.2 ISlin1 transposase 1444100 1150784 LA_1441 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_711622.2 1442931 R 189518 CDS NP_711624.1 24214143 1150786 complement(1444962..1445138) 1 NC_004342.2 hypothetical protein 1445138 1150786 LA_1444 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711624.1 1444962 R 189518 CDS NP_711625.1 24214144 1150787 1445118..1445726 1 NC_004342.2 hypothetical protein 1445726 1150787 LA_1443 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711625.1 1445118 D 189518 CDS NP_711626.2 294827874 1150788 1445726..1447162 1 NC_004342.2 outer membrane TolC superfamily protein 1447162 1150788 LA_1445 Leptospira interrogans serovar Lai str. 56601 outer membrane TolC superfamily protein NP_711626.2 1445726 D 189518 CDS NP_711627.1 24214146 1150789 1447180..1448361 1 NC_004342.2 heavy metal efflux pump 1448361 1150789 LA_1446 Leptospira interrogans serovar Lai str. 56601 heavy metal efflux pump NP_711627.1 1447180 D 189518 CDS NP_711628.2 294827875 1150790 1448414..1449025 1 NC_004342.2 Represses a number of genes involved in the response to DNA damage; LexA repressor 1449025 lexA 1150790 lexA Leptospira interrogans serovar Lai str. 56601 LexA repressor NP_711628.2 1448414 D 189518 CDS NP_711629.2 294827876 1150791 1449064..1449354 1 NC_004342.2 hypothetical protein 1449354 1150791 LA_1448 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711629.2 1449064 D 189518 CDS NP_711630.1 24214149 1150792 1449344..1450732 1 NC_004342.2 carboxy-terminal processing protease 1450732 prc 1150792 prc Leptospira interrogans serovar Lai str. 56601 carboxy-terminal processing protease NP_711630.1 1449344 D 189518 CDS NP_711631.1 24214150 1150793 1450737..1451753 1 NC_004342.2 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1451753 qri7 1150793 qri7 Leptospira interrogans serovar Lai str. 56601 DNA-binding/iron metalloprotein/AP endonuclease NP_711631.1 1450737 D 189518 CDS NP_711632.1 24214151 1150794 1451750..1452514 1 NC_004342.2 CDP-diacylglycerol--serine O- phosphatidyltransferase 1452514 pssA 1150794 pssA Leptospira interrogans serovar Lai str. 56601 CDP-diacylglycerol--serine O- phosphatidyltransferase NP_711632.1 1451750 D 189518 CDS NP_711633.1 24214152 1150795 complement(1452672..1453847) 1 NC_004342.2 hypothetical protein 1453847 1150795 LA_1452 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711633.1 1452672 R 189518 CDS NP_711634.1 24214153 1150796 complement(1454050..1454553) 1 NC_004342.2 hypothetical protein 1454553 1150796 LA_1453 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711634.1 1454050 R 189518 CDS NP_711635.1 24214154 1150797 complement(1454550..1455626) 1 NC_004342.2 hypothetical protein 1455626 1150797 LA_1454 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711635.1 1454550 R 189518 CDS NP_711636.2 294827877 1150798 1456029..1456145 1 NC_004342.2 hypothetical protein 1456145 1150798 LA_1455 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711636.2 1456029 D 189518 CDS NP_711637.1 24214156 1150799 1456142..1456840 1 NC_004342.2 DNA repair protein RadC 1456840 radC 1150799 radC Leptospira interrogans serovar Lai str. 56601 DNA repair protein RadC NP_711637.1 1456142 D 189518 CDS NP_711638.1 24214157 1150800 1456834..1457589 1 NC_004342.2 ABC transporter membrane protein 1457589 tagG 1150800 tagG Leptospira interrogans serovar Lai str. 56601 ABC transporter membrane protein NP_711638.1 1456834 D 189518 CDS NP_711639.1 24214158 1150801 1457586..1458884 1 NC_004342.2 ABC transporter ATP-binding protein 1458884 tagH 1150801 tagH Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_711639.1 1457586 D 189518 CDS NP_711640.1 24214159 1150802 1458933..1460243 1 NC_004342.2 UDP-glucose 6-dehydrogenase 1460243 ugd 1150802 ugd Leptospira interrogans serovar Lai str. 56601 UDP-glucose 6-dehydrogenase NP_711640.1 1458933 D 189518 CDS YP_003573308.1 294827878 9006901 complement(1460753..1461109) 1 NC_004342.2 hypothetical protein 1461109 9006901 LA_1459a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573308.1 1460753 R 189518 CDS NP_711642.2 294827879 1150804 1461274..1462443 1 NC_004342.2 ISlin1 transposase 1462443 1150804 LA_1461 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_711642.2 1461274 D 189518 CDS NP_711643.2 294827880 1150805 complement(1462722..1463837) 1 NC_004342.2 phosphoribosylaminoimidazole carboxylase ATPase subunit 1463837 purK 1150805 purK Leptospira interrogans serovar Lai str. 56601 phosphoribosylaminoimidazole carboxylase ATPase subunit NP_711643.2 1462722 R 189518 CDS NP_711644.1 24214163 1150806 complement(1463849..1464337) 1 NC_004342.2 phosphoribosylaminoimidazole carboxylase catalytic subunit 1464337 purE 1150806 purE Leptospira interrogans serovar Lai str. 56601 phosphoribosylaminoimidazole carboxylase catalytic subunit NP_711644.1 1463849 R 189518 CDS NP_711645.1 24214164 1150807 complement(1464388..1465788) 1 NC_004342.2 UDP-N-acetylmuramyl pentapeptide synthase 1465788 murF 1150807 murF Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylmuramyl pentapeptide synthase NP_711645.1 1464388 R 189518 CDS NP_711647.2 294827881 1150809 1466022..1467701 1 NC_004342.2 oligo-1,6-glucosidase 1467701 amyA 1150809 amyA Leptospira interrogans serovar Lai str. 56601 oligo-1,6-glucosidase NP_711647.2 1466022 D 189518 CDS NP_711648.2 294827882 1150810 complement(1468878..1469216) 1 NC_004342.2 hypothetical protein 1469216 1150810 LA_1467 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711648.2 1468878 R 189518 CDS NP_711649.1 24214168 1150811 complement(1469222..1469545) 1 NC_004342.2 hypothetical protein 1469545 1150811 LA_1468 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711649.1 1469222 R 189518 CDS YP_003573309.1 294827883 9006902 complement(1469567..1470010) 1 NC_004342.2 hypothetical protein 1470010 9006902 LA_1468a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573309.1 1469567 R 189518 CDS NP_711651.2 294827884 1150813 complement(1470711..1471895) 1 NC_004342.2 hypothetical protein 1471895 1150813 LA_1470 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711651.2 1470711 R 189518 CDS NP_711652.2 294827885 1150814 1471969..1474056 1 NC_004342.2 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 1474056 hppA 1150814 hppA Leptospira interrogans serovar Lai str. 56601 membrane-bound proton-translocating pyrophosphatase NP_711652.2 1471969 D 189518 CDS NP_711654.2 294827886 1150816 complement(1474433..1474969) 1 NC_004342.2 hypothetical protein 1474969 1150816 LA_1473 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711654.2 1474433 R 189518 CDS NP_711655.2 294827887 1150817 1475295..1476188 1 NC_004342.2 hypothetical protein 1476188 1150817 LA_1474 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711655.2 1475295 D 189518 CDS NP_711657.1 24214176 1150819 complement(1477310..1478566) 1 NC_004342.2 3-deoxy-D-manno-octulosonic-acid transferase 1478566 kdtA 1150819 kdtA Leptospira interrogans serovar Lai str. 56601 3-deoxy-D-manno-octulosonic-acid transferase NP_711657.1 1477310 R 189518 CDS NP_711658.2 294827888 1150820 1478573..1479190 1 NC_004342.2 dehalogenase-like hydrolase 1479190 1150820 LA_1476 Leptospira interrogans serovar Lai str. 56601 dehalogenase-like hydrolase NP_711658.2 1478573 D 189518 CDS NP_711659.2 294827889 1150821 complement(1479162..1479911) 1 NC_004342.2 hypothetical protein 1479911 1150821 LA_1478 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711659.2 1479162 R 189518 CDS NP_711660.1 24214179 1150822 1479990..1480718 1 NC_004342.2 hypothetical protein 1480718 1150822 LA_1479 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711660.1 1479990 D 189518 CDS NP_711661.1 24214180 1150823 1480720..1481388 1 NC_004342.2 PLP dependent enzyme class III 1481388 1150823 LA_1480 Leptospira interrogans serovar Lai str. 56601 PLP dependent enzyme class III NP_711661.1 1480720 D 189518 CDS NP_711662.2 294827890 1150824 1481390..1482163 1 NC_004342.2 pyrroline-5-carboxylate reductase 1482163 proC 1150824 proC Leptospira interrogans serovar Lai str. 56601 pyrroline-5-carboxylate reductase NP_711662.2 1481390 D 189518 CDS NP_711664.1 24214183 1150826 1482969..1484027 1 NC_004342.2 response regulator 1484027 1150826 LA_1483 Leptospira interrogans serovar Lai str. 56601 response regulator NP_711664.1 1482969 D 189518 CDS NP_711666.1 24214185 1150828 1485168..1485398 1 NC_004342.2 hypothetical protein 1485398 1150828 LA_1484 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711666.1 1485168 D 189518 CDS NP_711667.1 24214186 1150829 1485377..1486324 1 NC_004342.2 hypothetical protein 1486324 1150829 LA_1486 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711667.1 1485377 D 189518 CDS NP_711668.1 24214187 1150830 1486321..1487448 1 NC_004342.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1487448 mnmA 1150830 mnmA Leptospira interrogans serovar Lai str. 56601 tRNA-specific 2-thiouridylase MnmA NP_711668.1 1486321 D 189518 CDS NP_711669.1 24214188 1150831 1487465..1489747 1 NC_004342.2 glycolate oxidase 1489747 lldD 1150831 lldD Leptospira interrogans serovar Lai str. 56601 glycolate oxidase NP_711669.1 1487465 D 189518 CDS NP_711670.1 24214189 1150832 1489828..1490901 1 NC_004342.2 hypothetical protein 1490901 1150832 LA_1489 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711670.1 1489828 D 189518 CDS NP_711671.1 24214190 1150833 1490910..1492007 1 NC_004342.2 ribosomal large subunit pseudouridine synthase 1492007 rluA 1150833 rluA Leptospira interrogans serovar Lai str. 56601 ribosomal large subunit pseudouridine synthase NP_711671.1 1490910 D 189518 CDS NP_711672.2 294827891 1150834 1492004..1492744 1 NC_004342.2 Na+/H+ antiporter 1492744 nhaC 1150834 nhaC Leptospira interrogans serovar Lai str. 56601 Na+/H+ antiporter NP_711672.2 1492004 D 189518 CDS NP_711673.2 294827892 1150835 1492753..1493409 1 NC_004342.2 Na+/H+ antiporter 1493409 1150835 LA_1492 Leptospira interrogans serovar Lai str. 56601 Na+/H+ antiporter NP_711673.2 1492753 D 189518 CDS NP_711674.1 24214193 1150836 1493606..1494127 1 NC_004342.2 M23 family metalloendopeptidase 1494127 nlpD 1150836 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_711674.1 1493606 D 189518 CDS NP_711675.1 24214194 1150837 1494286..1494519 1 NC_004342.2 hypothetical protein 1494519 1150837 LA_1494 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711675.1 1494286 D 189518 CDS NP_711676.1 24214195 1150838 1494762..1495757 1 NC_004342.2 hypothetical protein 1495757 1150838 LA_1495 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711676.1 1494762 D 189518 CDS NP_711677.1 24214196 1150839 1495787..1496395 1 NC_004342.2 hypothetical protein 1496395 1150839 LA_1496 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711677.1 1495787 D 189518 CDS NP_711678.1 24214197 1150840 complement(1497027..1497434) 1 NC_004342.2 hypothetical protein 1497434 1150840 LA_1497 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711678.1 1497027 R 189518 CDS NP_711679.2 294827893 1150841 complement(1497458..1498279) 1 NC_004342.2 hypothetical protein 1498279 1150841 LA_1498 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711679.2 1497458 R 189518 CDS NP_711680.2 294827894 1150842 complement(1498368..1501958) 1 NC_004342.2 cytoplasmic membrane protein 1501958 1150842 LA_1499 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_711680.2 1498368 R 189518 CDS NP_711682.1 24214201 1150844 1502920..1504371 1 NC_004342.2 hypothetical protein 1504371 1150844 LA_1501 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711682.1 1502920 D 189518 CDS NP_711684.1 24214203 1150846 complement(1505355..1505867) 1 NC_004342.2 acetyltransferase 1505867 1150846 LA_1503 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_711684.1 1505355 R 189518 CDS NP_711685.1 24214204 1150847 1506511..1507170 1 NC_004342.2 M23 family metalloendopeptidase 1507170 nlpD 1150847 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_711685.1 1506511 D 189518 CDS NP_711687.2 294827895 1150849 complement(1507592..1508002) 1 NC_004342.2 hypothetical protein 1508002 1150849 LA_1506 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711687.2 1507592 R 189518 CDS NP_711688.2 294827896 1150850 1507883..1509466 1 NC_004342.2 hypothetical protein 1509466 1150850 LA_1507 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711688.2 1507883 D 189518 CDS NP_711689.1 24214208 1150851 1509474..1510157 1 NC_004342.2 hypothetical protein 1510157 1150851 LA_1508 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711689.1 1509474 D 189518 CDS NP_711691.2 294827897 1150853 1510689..1512293 1 NC_004342.2 hypothetical protein 1512293 1150853 LA_1510 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711691.2 1510689 D 189518 CDS NP_711692.1 24214211 1150854 complement(1512370..1513968) 1 NC_004342.2 L-aspartate oxidase 1513968 nadB 1150854 nadB Leptospira interrogans serovar Lai str. 56601 L-aspartate oxidase NP_711692.1 1512370 R 189518 CDS NP_711693.2 294827898 1150855 complement(1513970..1515760) 1 NC_004342.2 carboxy-terminal processing protease 1515760 prc 1150855 prc Leptospira interrogans serovar Lai str. 56601 carboxy-terminal processing protease NP_711693.2 1513970 R 189518 CDS NP_711694.1 24214213 1150856 1515735..1516754 1 NC_004342.2 hypothetical protein 1516754 1150856 LA_1512 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711694.1 1515735 D 189518 CDS NP_711695.1 24214214 1150857 complement(1516726..1517478) 1 NC_004342.2 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1517478 pdxJ 1150857 pdxJ Leptospira interrogans serovar Lai str. 56601 pyridoxine 5'-phosphate synthase NP_711695.1 1516726 R 189518 CDS NP_711696.2 294827899 1150858 1517844..1518320 1 NC_004342.2 hypothetical protein 1518320 1150858 LA_1515 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711696.2 1517844 D 189518 CDS NP_711697.1 24214216 1150859 1518330..1519223 1 NC_004342.2 tRNA isopentenyltransferase 1519223 miaA 1150859 miaA Leptospira interrogans serovar Lai str. 56601 tRNA isopentenyltransferase NP_711697.1 1518330 D 189518 CDS NP_711698.1 24214217 1150860 1519240..1519497 1 NC_004342.2 host factor I related protein 1519497 hfq 1150860 hfq Leptospira interrogans serovar Lai str. 56601 host factor I related protein NP_711698.1 1519240 D 189518 CDS YP_003573310.1 294827900 9006904 1519497..1520372 1 NC_004342.2 hypothetical protein 1520372 9006904 LA_1517a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573310.1 1519497 D 189518 CDS NP_711699.1 24214218 1150861 1520369..1521430 1 NC_004342.2 mannose-1-phosphate guanylyltransferase 1521430 manC 1150861 manC Leptospira interrogans serovar Lai str. 56601 mannose-1-phosphate guanylyltransferase NP_711699.1 1520369 D 189518 CDS NP_711700.2 294827901 1150862 complement(1521473..1521664) 1 NC_004342.2 hypothetical protein 1521664 1150862 LA_1519 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711700.2 1521473 R 189518 CDS NP_711701.2 294827902 1150863 1521655..1522392 1 NC_004342.2 hypothetical protein 1522392 1150863 LA_1520 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711701.2 1521655 D 189518 CDS NP_711702.1 24214221 1150864 1522401..1522865 1 NC_004342.2 chemotaxis protein CheW 1522865 cheW 1150864 cheW Leptospira interrogans serovar Lai str. 56601 chemotaxis protein CheW NP_711702.1 1522401 D 189518 CDS NP_711703.1 24214222 1150865 1522855..1524822 1 NC_004342.2 hypothetical protein 1524822 1150865 LA_1522 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711703.1 1522855 D 189518 CDS NP_711704.1 24214223 1150866 complement(1524838..1525353) 1 NC_004342.2 hypothetical protein 1525353 1150866 LA_1523 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711704.1 1524838 R 189518 CDS NP_711705.1 24214224 1150867 complement(1525350..1525544) 1 NC_004342.2 hypothetical protein 1525544 1150867 LA_1524 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711705.1 1525350 R 189518 CDS NP_711707.1 24214226 1150869 complement(1525725..1526165) 1 NC_004342.2 signal transduction protein 1526165 1150869 LA_1526 Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_711707.1 1525725 R 189518 CDS NP_711709.2 294827903 1150871 1526549..1528003 1 NC_004342.2 two-component response regulator 1528003 1150871 LA_1528 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_711709.2 1526549 D 189518 CDS YP_003573311.1 294827904 9006905 1528074..1528223 1 NC_004342.2 IS1533 transposase 1528223 9006905 LA_1528a Leptospira interrogans serovar Lai str. 56601 IS1533 transposase YP_003573311.1 1528074 D 189518 CDS NP_711711.1 24214230 1150873 complement(1528568..1529071) 1 NC_004342.2 hypothetical protein 1529071 1150873 LA_1530 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711711.1 1528568 R 189518 CDS NP_711713.1 24214232 1150875 1530167..1531222 1 NC_004342.2 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 1531222 fbaB 1150875 fbaB Leptospira interrogans serovar Lai str. 56601 fructose-bisphosphate aldolase NP_711713.1 1530167 D 189518 CDS NP_711714.2 294827905 1150876 complement(1532130..1533704) 1 NC_004342.2 thymidylate synthase 1533704 1150876 LA_1533 Leptospira interrogans serovar Lai str. 56601 thymidylate synthase NP_711714.2 1532130 R 189518 CDS NP_711716.1 24214235 1150878 1534249..1534806 1 NC_004342.2 hypothetical protein 1534806 1150878 LA_1535 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711716.1 1534249 D 189518 CDS NP_711717.1 24214236 1150879 1534920..1535567 1 NC_004342.2 hypothetical protein 1535567 1150879 LA_1536 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711717.1 1534920 D 189518 CDS NP_711718.1 24214237 1150880 1535568..1536050 1 NC_004342.2 hypothetical protein 1536050 1150880 LA_1537 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711718.1 1535568 D 189518 CDS NP_711719.1 24214238 1150881 complement(1536189..1536671) 1 NC_004342.2 hypothetical protein 1536671 1150881 LA_1538 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711719.1 1536189 R 189518 CDS NP_711720.1 24214239 1150882 complement(1536692..1537192) 1 NC_004342.2 hypothetical protein 1537192 1150882 LA_1539 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711720.1 1536692 R 189518 CDS NP_711722.1 24214241 1150884 complement(1537958..1538860) 1 NC_004342.2 phospholipase 1538860 1150884 LA_1541 Leptospira interrogans serovar Lai str. 56601 phospholipase NP_711722.1 1537958 R 189518 CDS NP_711723.1 24214242 1150885 complement(1538823..1540841) 1 NC_004342.2 hypothetical protein 1540841 1150885 LA_1542 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711723.1 1538823 R 189518 CDS NP_711724.1 24214243 1150886 complement(1541313..1544609) 1 NC_004342.2 heavy metal efflux pump 1544609 1150886 LA_1543 Leptospira interrogans serovar Lai str. 56601 heavy metal efflux pump NP_711724.1 1541313 R 189518 CDS NP_711725.2 294827906 1150887 1544957..1545454 1 NC_004342.2 hypothetical protein 1545454 1150887 LA_1544 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711725.2 1544957 D 189518 CDS NP_711727.1 24214246 1150889 complement(1546092..1547186) 1 NC_004342.2 DNA methyltransferase 1547186 1150889 LA_1547 Leptospira interrogans serovar Lai str. 56601 DNA methyltransferase NP_711727.1 1546092 R 189518 CDS NP_711729.2 294827907 1150891 complement(1547320..1549545) 1 NC_004342.2 sodium/hydrogen antiporter 1549545 kefB 1150891 kefB Leptospira interrogans serovar Lai str. 56601 sodium/hydrogen antiporter NP_711729.2 1547320 R 189518 CDS NP_711730.1 24214249 1150892 complement(1549592..1550443) 1 NC_004342.2 beta-lactamase regulatory protein 1 1550443 1150892 LA_1549 Leptospira interrogans serovar Lai str. 56601 beta-lactamase regulatory protein 1 NP_711730.1 1549592 R 189518 CDS NP_711731.2 294827908 1150893 complement(1550444..1550965) 1 NC_004342.2 hypothetical protein 1550965 1150893 LA_1550 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711731.2 1550444 R 189518 CDS NP_711733.1 24214252 1150895 complement(1551142..1552443) 1 NC_004342.2 histidine kinase sensor protein 1552443 1150895 LA_1552 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_711733.1 1551142 R 189518 CDS NP_711734.1 24214253 1150896 1552687..1554708 1 NC_004342.2 hypothetical protein 1554708 1150896 LA_1553 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711734.1 1552687 D 189518 CDS NP_711735.2 294827909 1150897 1554749..1555063 1 NC_004342.2 hypothetical protein 1555063 1150897 LA_1554 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711735.2 1554749 D 189518 CDS NP_711736.1 24214255 1150898 1555050..1556081 1 NC_004342.2 multicopper oxidase-like protein 1556081 1150898 LA_1555 Leptospira interrogans serovar Lai str. 56601 multicopper oxidase-like protein NP_711736.1 1555050 D 189518 CDS NP_711737.1 24214256 1150899 1556428..1557021 1 NC_004342.2 cytochrome oxidase assembly factor 1557021 1150899 LA_1556 Leptospira interrogans serovar Lai str. 56601 cytochrome oxidase assembly factor NP_711737.1 1556428 D 189518 CDS NP_711740.1 24214259 1150902 1557366..1557581 1 NC_004342.2 hypothetical protein 1557581 1150902 LA_1559 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711740.1 1557366 D 189518 CDS NP_711741.1 24214260 1150903 complement(1557799..1558107) 1 NC_004342.2 hypothetical protein 1558107 1150903 LA_1560 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711741.1 1557799 R 189518 CDS NP_711744.1 24214263 1150906 complement(1559486..1559878) 1 NC_004342.2 Hsp20/alpha crystallin molecular chaperone 1559878 ibpA 1150906 ibpA Leptospira interrogans serovar Lai str. 56601 Hsp20/alpha crystallin molecular chaperone NP_711744.1 1559486 R 189518 CDS NP_711745.1 24214264 1150907 complement(1559899..1560315) 1 NC_004342.2 Hsp20/alpha crystallin molecular chaperone 1560315 ibpA 1150907 ibpA Leptospira interrogans serovar Lai str. 56601 Hsp20/alpha crystallin molecular chaperone NP_711745.1 1559899 R 189518 CDS NP_711746.1 24214265 1150908 complement(1560784..1561389) 1 NC_004342.2 ISlin1 transposase 1561389 1150908 LA_1565 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_711746.1 1560784 R 189518 CDS NP_711747.1 24214266 1150909 complement(1561627..1561950) 1 NC_004342.2 ISlin1 transposase 1561950 1150909 LA_1566 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_711747.1 1561627 R 189518 CDS NP_711748.2 294827910 1150910 complement(1562896..1563645) 1 NC_004342.2 hypothetical protein 1563645 1150910 LA_1567 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711748.2 1562896 R 189518 CDS NP_711749.1 24214268 1150911 complement(1563626..1564306) 1 NC_004342.2 hypothetical protein 1564306 1150911 LA_1568 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711749.1 1563626 R 189518 CDS NP_711750.1 24214269 1150912 complement(1564754..1566178) 1 NC_004342.2 hypothetical protein 1566178 1150912 LA_1569 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711750.1 1564754 R 189518 CDS NP_711753.1 24214272 1150915 complement(1567067..1567624) 1 NC_004342.2 hypothetical protein 1567624 1150915 LA_1572 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711753.1 1567067 R 189518 CDS NP_711757.2 294827911 1150919 1570319..1570612 1 NC_004342.2 transcriptional regulator 1570612 1150919 LA_1576 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711757.2 1570319 D 189518 CDS NP_711758.1 24214277 1150920 1570617..1571561 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 1571561 wcaG 1150920 wcaG Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_711758.1 1570617 D 189518 CDS NP_711759.1 24214278 1150921 1571578..1572675 1 NC_004342.2 FAD dependent oxidoreductase 1572675 1150921 LA_1578 Leptospira interrogans serovar Lai str. 56601 FAD dependent oxidoreductase NP_711759.1 1571578 D 189518 CDS NP_711760.1 24214279 1150922 1572707..1573264 1 NC_004342.2 phosphoheptose isomerase 1573264 gmhA 1150922 gmhA Leptospira interrogans serovar Lai str. 56601 phosphoheptose isomerase NP_711760.1 1572707 D 189518 CDS NP_711761.1 24214280 1150923 1573271..1574260 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 1574260 wcaG 1150923 wcaG Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_711761.1 1573271 D 189518 CDS NP_711762.1 24214281 1150924 1574241..1575044 1 NC_004342.2 nucleotidyl transferase 1575044 gcd1 1150924 gcd1 Leptospira interrogans serovar Lai str. 56601 nucleotidyl transferase NP_711762.1 1574241 D 189518 CDS NP_711763.2 294827912 1150925 1575041..1576570 1 NC_004342.2 ADP-heptose synthetase 1576570 rfaE 1150925 rfaE Leptospira interrogans serovar Lai str. 56601 ADP-heptose synthetase NP_711763.2 1575041 D 189518 CDS NP_711764.1 24214283 1150926 1576573..1577565 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 1577565 wcaG 1150926 wcaG Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_711764.1 1576573 D 189518 CDS NP_711765.1 24214284 1150927 1577562..1579178 1 NC_004342.2 hypothetical protein 1579178 1150927 LA_1584 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711765.1 1577562 D 189518 CDS NP_711766.1 24214285 1150928 1579191..1579985 1 NC_004342.2 hypothetical protein 1579985 1150928 LA_1585 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711766.1 1579191 D 189518 CDS NP_711767.2 294827913 1150929 1579976..1580929 1 NC_004342.2 hypothetical protein 1580929 1150929 LA_1586 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711767.2 1579976 D 189518 CDS NP_711768.1 24214287 1150930 1581309..1582103 1 NC_004342.2 hypothetical protein 1582103 1150930 LA_1587 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711768.1 1581309 D 189518 CDS NP_711769.1 24214288 1150931 1582100..1582495 1 NC_004342.2 hypothetical protein 1582495 1150931 LA_1588 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711769.1 1582100 D 189518 CDS NP_711770.1 24214289 1150932 1582499..1582933 1 NC_004342.2 NUDIX hydrolase 1582933 1150932 LA_1589 Leptospira interrogans serovar Lai str. 56601 NUDIX hydrolase NP_711770.1 1582499 D 189518 CDS NP_711771.1 24214290 1150933 1582940..1583605 1 NC_004342.2 SAM-dependent methyltransferase 1583605 1150933 LA_1590 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_711771.1 1582940 D 189518 CDS NP_711772.1 24214291 1150934 complement(1583886..1584068) 1 NC_004342.2 hypothetical protein 1584068 1150934 LA_1591 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711772.1 1583886 R 189518 CDS NP_711773.1 24214292 1150935 1584180..1585361 1 NC_004342.2 D-mycarose 3-C-methyltransferase 1585361 1150935 LA_1592 Leptospira interrogans serovar Lai str. 56601 D-mycarose 3-C-methyltransferase NP_711773.1 1584180 D 189518 CDS NP_711774.1 24214293 1150936 1585354..1585881 1 NC_004342.2 hypothetical protein 1585881 1150936 LA_1593 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711774.1 1585354 D 189518 CDS NP_711775.1 24214294 1150937 1585878..1587095 1 NC_004342.2 methyltransferase 1587095 1150937 LA_1594 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_711775.1 1585878 D 189518 CDS NP_711776.1 24214295 1150938 1587097..1588173 1 NC_004342.2 pyridoxal phosphate-dependent aminotransferase 1588173 wecE 1150938 wecE Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate-dependent aminotransferase NP_711776.1 1587097 D 189518 CDS NP_711777.2 294827914 1150939 1588166..1589092 1 NC_004342.2 methionyl-tRNA(fmet) n-formyltransferase 1589092 1150939 LA_1596 Leptospira interrogans serovar Lai str. 56601 methionyl-tRNA(fmet) n-formyltransferase NP_711777.2 1588166 D 189518 CDS NP_711778.1 24214297 1150940 1589363..1589662 1 NC_004342.2 fucose synthetase 1589662 1150940 LA_1597 Leptospira interrogans serovar Lai str. 56601 fucose synthetase NP_711778.1 1589363 D 189518 CDS NP_711779.1 24214298 1150941 1589810..1590325 1 NC_004342.2 acetyltransferase 1590325 1150941 LA_1598 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_711779.1 1589810 D 189518 CDS NP_711780.1 24214299 1150942 1590322..1591575 1 NC_004342.2 hypothetical protein 1591575 1150942 LA_1599 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711780.1 1590322 D 189518 CDS NP_711781.1 24214300 1150943 1591703..1593520 1 NC_004342.2 ABC transporter ATP-binding protein 1593520 sunT 1150943 sunT Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_711781.1 1591703 D 189518 CDS NP_711782.1 24214301 1150944 1593655..1594083 1 NC_004342.2 FdtA-like protein 1594083 1150944 LA_1601 Leptospira interrogans serovar Lai str. 56601 FdtA-like protein NP_711782.1 1593655 D 189518 CDS NP_711783.2 294827915 1150945 1594100..1594810 1 NC_004342.2 SAM-dependent methyltransferase 1594810 1150945 LA_1602 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_711783.2 1594100 D 189518 CDS NP_711784.1 24214303 1150946 1594812..1595759 1 NC_004342.2 glycosyltransferase 1595759 1150946 LA_1603 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711784.1 1594812 D 189518 CDS NP_711785.1 24214304 1150947 1595916..1597589 1 NC_004342.2 hypothetical protein 1597589 1150947 LA_1604 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711785.1 1595916 D 189518 CDS NP_711786.1 24214305 1150948 1597763..1598449 1 NC_004342.2 CMP-N-acetylneuraminic acid synthetase 1598449 neuA 1150948 neuA Leptospira interrogans serovar Lai str. 56601 CMP-N-acetylneuraminic acid synthetase NP_711786.1 1597763 D 189518 CDS NP_711787.1 24214306 1150949 1598452..1599444 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 1599444 wcaG 1150949 wcaG Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_711787.1 1598452 D 189518 CDS NP_711788.1 24214307 1150950 1599444..1600607 1 NC_004342.2 pyridoxal phosphate-dependent aminotransferase 1600607 wecE 1150950 wecE Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate-dependent aminotransferase NP_711788.1 1599444 D 189518 CDS NP_711789.2 294827916 1150951 1600600..1601220 1 NC_004342.2 hypothetical protein 1601220 1150951 LA_1608 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711789.2 1600600 D 189518 CDS NP_711790.1 24214309 1150952 1601198..1602232 1 NC_004342.2 N-acetylneuraminic (sialic) acid synthetase 1602232 spsE 1150952 spsE Leptospira interrogans serovar Lai str. 56601 N-acetylneuraminic (sialic) acid synthetase NP_711790.1 1601198 D 189518 CDS NP_711791.1 24214310 1150953 1602229..1603392 1 NC_004342.2 UDP-N-acetylglucosamine 2-epimerase 1603392 1150953 LA_1610 Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylglucosamine 2-epimerase NP_711791.1 1602229 D 189518 CDS NP_711792.1 24214311 1150954 1603641..1604696 1 NC_004342.2 nucleotidyl transferase 1604696 gcd1 1150954 gcd1 Leptospira interrogans serovar Lai str. 56601 nucleotidyl transferase NP_711792.1 1603641 D 189518 CDS NP_711793.1 24214312 1150955 1605070..1606218 1 NC_004342.2 hypothetical protein 1606218 1150955 LA_1612 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711793.1 1605070 D 189518 CDS NP_711794.1 24214313 1150956 1606245..1608506 1 NC_004342.2 N-acetylneuraminic (sialic) acid synthetase 1608506 spsE 1150956 spsE Leptospira interrogans serovar Lai str. 56601 N-acetylneuraminic (sialic) acid synthetase NP_711794.1 1606245 D 189518 CDS NP_711795.1 24214314 1150957 1608528..1609712 1 NC_004342.2 pyridoxal phosphate-dependent aminotransferase 1609712 wecE 1150957 wecE Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate-dependent aminotransferase NP_711795.1 1608528 D 189518 CDS NP_711796.1 24214315 1150958 1609717..1610346 1 NC_004342.2 CMP-N-acetylneuraminic acid synthetase 1610346 neuA 1150958 neuA Leptospira interrogans serovar Lai str. 56601 CMP-N-acetylneuraminic acid synthetase NP_711796.1 1609717 D 189518 CDS NP_711797.1 24214316 1150959 1610420..1611487 1 NC_004342.2 alcohol dehydrogenase 1611487 1150959 LA_1616 Leptospira interrogans serovar Lai str. 56601 alcohol dehydrogenase NP_711797.1 1610420 D 189518 CDS NP_711798.1 24214317 1150960 1611488..1612465 1 NC_004342.2 molybdenum cofactor biosynthesis protein 1612465 1150960 LA_1617 Leptospira interrogans serovar Lai str. 56601 molybdenum cofactor biosynthesis protein NP_711798.1 1611488 D 189518 CDS NP_711799.1 24214318 1150961 1612729..1613592 1 NC_004342.2 methyltransferase-like protein 1613592 1150961 LA_1618 Leptospira interrogans serovar Lai str. 56601 methyltransferase-like protein NP_711799.1 1612729 D 189518 CDS NP_711800.1 24214319 1150962 1613905..1615713 1 NC_004342.2 carbamoyl transferase 1615713 nodU 1150962 nodU Leptospira interrogans serovar Lai str. 56601 carbamoyl transferase NP_711800.1 1613905 D 189518 CDS NP_711801.2 294827917 1150963 1615828..1617588 1 NC_004342.2 hypothetical protein 1617588 1150963 LA_1620 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711801.2 1615828 D 189518 CDS NP_711802.2 294827918 1150964 1617749..1618360 1 NC_004342.2 6-phosphogluconolactonase 1618360 nagB 1150964 nagB Leptospira interrogans serovar Lai str. 56601 6-phosphogluconolactonase NP_711802.2 1617749 D 189518 CDS NP_711803.1 24214322 1150965 1618473..1619069 1 NC_004342.2 acetyltransferase 1619069 wbbJ 1150965 wbbJ Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_711803.1 1618473 D 189518 CDS NP_711805.1 24214324 1150967 1619682..1620437 1 NC_004342.2 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 1620437 hpcH 1150967 hpcH Leptospira interrogans serovar Lai str. 56601 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase NP_711805.1 1619682 D 189518 CDS NP_711806.1 24214325 1150968 1620472..1621227 1 NC_004342.2 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1621227 kdsB 1150968 kdsB Leptospira interrogans serovar Lai str. 56601 3-deoxy-manno-octulosonate cytidylyltransferase NP_711806.1 1620472 D 189518 CDS NP_711807.1 24214326 1150969 1621230..1622258 1 NC_004342.2 oxidoreductase family protein 1622258 1150969 LA_1626 Leptospira interrogans serovar Lai str. 56601 oxidoreductase family protein NP_711807.1 1621230 D 189518 CDS NP_711808.1 24214327 1150970 1622271..1623044 1 NC_004342.2 inositol monophosphatase 1623044 suhB 1150970 suhB Leptospira interrogans serovar Lai str. 56601 inositol monophosphatase NP_711808.1 1622271 D 189518 CDS NP_711809.1 24214328 1150971 1623252..1624214 1 NC_004342.2 methylase/methyltransferase 1624214 1150971 LA_1628 Leptospira interrogans serovar Lai str. 56601 methylase/methyltransferase NP_711809.1 1623252 D 189518 CDS NP_711810.1 24214329 1150972 1624258..1625256 1 NC_004342.2 phosphoglycerate dehydrogenase and related dehydrogenase 1625256 serA 1150972 serA Leptospira interrogans serovar Lai str. 56601 phosphoglycerate dehydrogenase and related dehydrogenase NP_711810.1 1624258 D 189518 CDS NP_711811.2 294827919 1150973 1625249..1627141 1 NC_004342.2 hypothetical protein 1627141 1150973 LA_1630 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711811.2 1625249 D 189518 CDS NP_711812.1 24214331 1150974 1627152..1627919 1 NC_004342.2 nucleotidyl transferase 1627919 gcd1 1150974 gcd1 Leptospira interrogans serovar Lai str. 56601 nucleotidyl transferase NP_711812.1 1627152 D 189518 CDS NP_711813.1 24214332 1150975 1627922..1629013 1 NC_004342.2 CDP-glucose 4,6-dehydratase 1629013 1150975 LA_1632 Leptospira interrogans serovar Lai str. 56601 CDP-glucose 4,6-dehydratase NP_711813.1 1627922 D 189518 CDS NP_711814.2 294827920 1150976 1629016..1629468 1 NC_004342.2 dTDP-4-dehydrorhamnose epimerase 1629468 1150976 LA_1633 Leptospira interrogans serovar Lai str. 56601 dTDP-4-dehydrorhamnose epimerase NP_711814.2 1629016 D 189518 CDS NP_711815.2 294827921 1150977 1629468..1630421 1 NC_004342.2 UDP-glucose 4-epimerase 1630421 1150977 LA_1634 Leptospira interrogans serovar Lai str. 56601 UDP-glucose 4-epimerase NP_711815.2 1629468 D 189518 CDS NP_711816.1 24214335 1150978 1630429..1631325 1 NC_004342.2 glycosyltransferase 1631325 1150978 LA_1635 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711816.1 1630429 D 189518 CDS NP_711817.1 24214336 1150979 1631444..1631626 1 NC_004342.2 hypothetical protein 1631626 1150979 LA_1636 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711817.1 1631444 D 189518 CDS NP_711818.1 24214337 1150980 1631754..1632164 1 NC_004342.2 hypothetical protein 1632164 1150980 LA_1637 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711818.1 1631754 D 189518 CDS NP_711819.1 24214338 1150981 1632175..1633038 1 NC_004342.2 polysaccharide deacetylase 1633038 1150981 LA_1638 Leptospira interrogans serovar Lai str. 56601 polysaccharide deacetylase NP_711819.1 1632175 D 189518 CDS NP_711820.2 294827922 1150982 1633038..1635152 1 NC_004342.2 hypothetical protein 1635152 1150982 LA_1639 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711820.2 1633038 D 189518 CDS NP_711821.2 294827923 1150983 1635149..1637161 1 NC_004342.2 lipoprotein 1637161 1150983 LA_1640 Leptospira interrogans serovar Lai str. 56601 lipoprotein NP_711821.2 1635149 D 189518 CDS NP_711822.1 24214341 1150984 1637366..1638655 1 NC_004342.2 hypothetical protein 1638655 1150984 LA_1641 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711822.1 1637366 D 189518 CDS NP_711823.1 24214342 1150985 1638745..1639890 1 NC_004342.2 glycosyltransferase 1639890 1150985 LA_1642 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711823.1 1638745 D 189518 CDS NP_711824.1 24214343 1150986 1640408..1641442 1 NC_004342.2 polysaccharide biosynthesis protein 1641442 1150986 LA_1643 Leptospira interrogans serovar Lai str. 56601 polysaccharide biosynthesis protein NP_711824.1 1640408 D 189518 CDS NP_711825.1 24214344 1150987 1641449..1642549 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 1642549 1150987 LA_1644 Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_711825.1 1641449 D 189518 CDS NP_711826.1 24214345 1150988 1642553..1643683 1 NC_004342.2 UDP-N-acetylglucosamine 2-epimerase 1643683 wecB 1150988 wecB Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylglucosamine 2-epimerase NP_711826.1 1642553 D 189518 CDS NP_711827.1 24214346 1150989 1643693..1644880 1 NC_004342.2 glycosyltransferase 1644880 1150989 LA_1646 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711827.1 1643693 D 189518 CDS NP_711828.1 24214347 1150990 1644884..1646149 1 NC_004342.2 glycosyltransferase 1646149 wcaJ 1150990 wcaJ Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711828.1 1644884 D 189518 CDS NP_711829.1 24214348 1150991 1646199..1647467 1 NC_004342.2 hypothetical protein 1647467 1150991 LA_1648 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711829.1 1646199 D 189518 CDS NP_711830.1 24214349 1150992 1647791..1649134 1 NC_004342.2 membrane protein involved in the export of O-antigen and teichoic acid 1649134 1150992 LA_1649 Leptospira interrogans serovar Lai str. 56601 membrane protein involved in the export of O-antigen and teichoic acid NP_711830.1 1647791 D 189518 CDS NP_711831.1 24214350 1150993 1649138..1650079 1 NC_004342.2 glycosyltransferase 1650079 1150993 LA_1650 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711831.1 1649138 D 189518 CDS NP_711833.1 24214352 1150995 1650780..1651673 1 NC_004342.2 hypothetical protein 1651673 1150995 LA_1652 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711833.1 1650780 D 189518 CDS NP_711834.1 24214353 1150996 1652314..1653336 1 NC_004342.2 glycosyltransferase 1653336 1150996 LA_1653 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711834.1 1652314 D 189518 CDS NP_711835.1 24214354 1150997 1653486..1653905 1 NC_004342.2 FdtA-like protein 1653905 1150997 LA_1654 Leptospira interrogans serovar Lai str. 56601 FdtA-like protein NP_711835.1 1653486 D 189518 CDS NP_711836.1 24214355 1150998 1653919..1655010 1 NC_004342.2 pyridoxal phosphate-dependent aminotransferase 1655010 wecE 1150998 wecE Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate-dependent aminotransferase NP_711836.1 1653919 D 189518 CDS NP_711837.1 24214356 1150999 1655153..1655950 1 NC_004342.2 glycosyltransferase 1655950 1150999 LA_1656 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711837.1 1655153 D 189518 CDS NP_711838.1 24214357 1151000 1656460..1657281 1 NC_004342.2 glycosyltransferase 1657281 1151000 LA_1657 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711838.1 1656460 D 189518 CDS NP_711839.1 24214358 1151001 1657995..1659743 1 NC_004342.2 glycosyltransferase 1659743 1151001 LA_1658 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711839.1 1657995 D 189518 CDS NP_711840.1 24214359 1151002 1659939..1660499 1 NC_004342.2 dTDP-4-dehydrorhamnose 3,5-epimerase 1660499 rfbC 1151002 rfbC Leptospira interrogans serovar Lai str. 56601 dTDP-4-dehydrorhamnose 3,5-epimerase NP_711840.1 1659939 D 189518 CDS NP_711841.1 24214360 1151003 1660503..1661423 1 NC_004342.2 dTDP-4-dehydrorhamnose reductase 1661423 rfbD 1151003 rfbD Leptospira interrogans serovar Lai str. 56601 dTDP-4-dehydrorhamnose reductase NP_711841.1 1660503 D 189518 CDS NP_711842.2 294827924 1151004 1661420..1662469 1 NC_004342.2 dTDP-D-glucose 4,6-dehydratase 1662469 rfbB 1151004 rfbB Leptospira interrogans serovar Lai str. 56601 dTDP-D-glucose 4,6-dehydratase NP_711842.2 1661420 D 189518 CDS NP_711843.1 24214362 1151005 1662470..1663354 1 NC_004342.2 glucose-1-phosphate thymidylyltransferase 1663354 rfbA 1151005 rfbA Leptospira interrogans serovar Lai str. 56601 glucose-1-phosphate thymidylyltransferase NP_711843.1 1662470 D 189518 CDS NP_711844.2 294827925 1151006 1664405..1665310 1 NC_004342.2 glycosyltransferase 1665310 1151006 LA_1663 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711844.2 1664405 D 189518 CDS NP_711845.1 24214364 1151007 1665315..1666226 1 NC_004342.2 dTDP-rhamnosyl transferase 1666226 1151007 LA_1664 Leptospira interrogans serovar Lai str. 56601 dTDP-rhamnosyl transferase NP_711845.1 1665315 D 189518 CDS NP_711846.2 294827926 1151008 complement(1666311..1666643) 1 NC_004342.2 hypothetical protein 1666643 1151008 LA_1665 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711846.2 1666311 R 189518 CDS NP_711847.1 24214366 1151009 1666552..1667400 1 NC_004342.2 glycosyltransferase 1667400 1151009 LA_1666 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_711847.1 1666552 D 189518 CDS NP_711848.1 24214367 1151010 1667441..1668835 1 NC_004342.2 sodium:sulfate symporter 1668835 citT 1151010 citT Leptospira interrogans serovar Lai str. 56601 sodium:sulfate symporter NP_711848.1 1667441 D 189518 CDS NP_711849.2 294827927 1151011 1669971..1670225 1 NC_004342.2 hypothetical protein 1670225 1151011 LA_1668 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711849.2 1669971 D 189518 CDS NP_711850.1 24214369 1151012 1670226..1670660 1 NC_004342.2 hypothetical protein 1670660 1151012 LA_1669 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711850.1 1670226 D 189518 CDS NP_711852.1 24214371 1151014 1670959..1672911 1 NC_004342.2 ankyrin-like protein 1672911 1151014 LA_1671 Leptospira interrogans serovar Lai str. 56601 ankyrin-like protein NP_711852.1 1670959 D 189518 CDS NP_711855.1 24214374 1151017 1673292..1674521 1 NC_004342.2 poly-gamma-glutamate synthesis protein 1674521 1151017 LA_1674 Leptospira interrogans serovar Lai str. 56601 poly-gamma-glutamate synthesis protein NP_711855.1 1673292 D 189518 CDS NP_711856.1 24214375 1151018 1674586..1674861 1 NC_004342.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1674861 rpsF 1151018 rpsF Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S6 NP_711856.1 1674586 D 189518 CDS NP_711857.1 24214376 1151019 1674854..1675306 1 NC_004342.2 single-stranded DNA-binding protein 1675306 ssb 1151019 ssb Leptospira interrogans serovar Lai str. 56601 single-stranded DNA-binding protein NP_711857.1 1674854 D 189518 CDS NP_711858.1 24214377 1151020 1675318..1675629 1 NC_004342.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1675629 rpsR 1151020 rpsR Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S18 NP_711858.1 1675318 D 189518 CDS NP_711859.1 24214378 1151021 1675639..1676088 1 NC_004342.2 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1676088 rplI 1151021 rplI Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L9 NP_711859.1 1675639 D 189518 CDS NP_711860.1 24214379 1151022 1676106..1677434 1 NC_004342.2 replicative DNA helicase 1677434 dnaB 1151022 dnaB Leptospira interrogans serovar Lai str. 56601 replicative DNA helicase NP_711860.1 1676106 D 189518 CDS NP_711861.1 24214380 1151023 1677467..1679272 1 NC_004342.2 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1679272 aspS 1151023 aspS Leptospira interrogans serovar Lai str. 56601 aspartyl-tRNA synthetase NP_711861.1 1677467 D 189518 CDS NP_711862.1 24214381 1151024 1679382..1679669 1 NC_004342.2 phosphate starvation-inducibleprotein 1679669 1151024 LA_1681 Leptospira interrogans serovar Lai str. 56601 phosphate starvation-inducibleprotein NP_711862.1 1679382 D 189518 CDS NP_711863.1 24214382 1151025 1679700..1680263 1 NC_004342.2 phosphate starvation-inducible protein 1680263 phoH 1151025 phoH Leptospira interrogans serovar Lai str. 56601 phosphate starvation-inducible protein NP_711863.1 1679700 D 189518 CDS NP_711864.1 24214383 1151026 1680268..1682682 1 NC_004342.2 membrane-associated HD superfamily hydrolase 1682682 1151026 LA_1683 Leptospira interrogans serovar Lai str. 56601 membrane-associated HD superfamily hydrolase NP_711864.1 1680268 D 189518 CDS NP_711865.1 24214384 1151027 1682751..1683176 1 NC_004342.2 metal-dependent hydrolase 1683176 1151027 LA_1684 Leptospira interrogans serovar Lai str. 56601 metal-dependent hydrolase NP_711865.1 1682751 D 189518 CDS NP_711866.1 24214385 1151028 1683149..1683931 1 NC_004342.2 recombinational DNA repair protein 1683931 1151028 LA_1685 Leptospira interrogans serovar Lai str. 56601 recombinational DNA repair protein NP_711866.1 1683149 D 189518 CDS NP_711867.2 294827928 1151029 1683915..1684160 1 NC_004342.2 hypothetical protein 1684160 1151029 LA_1686 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711867.2 1683915 D 189518 CDS NP_711869.2 294827929 1151031 1684563..1686323 1 NC_004342.2 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1686323 argS 1151031 argS Leptospira interrogans serovar Lai str. 56601 arginyl-tRNA synthetase NP_711869.2 1684563 D 189518 CDS NP_711870.1 24214389 1151032 1686323..1687579 1 NC_004342.2 competence-damage inducible protein CinA 1687579 1151032 LA_1689 Leptospira interrogans serovar Lai str. 56601 competence-damage inducible protein CinA NP_711870.1 1686323 D 189518 CDS NP_711871.1 24214390 1151033 1687576..1688655 1 NC_004342.2 hypothetical protein 1688655 1151033 LA_1690 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711871.1 1687576 D 189518 CDS NP_711872.1 24214391 1151034 complement(1688933..1690369) 1 NC_004342.2 hypothetical protein 1690369 1151034 LA_1691 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711872.1 1688933 R 189518 CDS NP_711873.1 24214392 1151035 complement(1690926..1691918) 1 NC_004342.2 receiver component of a two-component response regulator 1691918 1151035 LA_1692 Leptospira interrogans serovar Lai str. 56601 receiver component of a two-component response regulator NP_711873.1 1690926 R 189518 CDS NP_711874.1 24214393 1151036 complement(1691918..1693051) 1 NC_004342.2 signal transduction histidine kinase 1693051 baeS 1151036 baeS Leptospira interrogans serovar Lai str. 56601 signal transduction histidine kinase NP_711874.1 1691918 R 189518 CDS NP_711875.1 24214394 1151037 complement(1693058..1693714) 1 NC_004342.2 hypothetical protein 1693714 1151037 LA_1694 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711875.1 1693058 R 189518 CDS NP_711876.2 294827930 1151038 complement(1693782..1694117) 1 NC_004342.2 preprotein translocase subunit SecG 1694117 secG 1151038 secG Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit SecG NP_711876.2 1693782 R 189518 CDS NP_711877.1 24214396 1151039 complement(1694214..1694966) 1 NC_004342.2 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1694966 tpiA 1151039 tpiA Leptospira interrogans serovar Lai str. 56601 triosephosphate isomerase NP_711877.1 1694214 R 189518 CDS NP_711879.2 294827931 1151041 1695655..1696413 1 NC_004342.2 hypothetical protein 1696413 1151041 LA_1698 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711879.2 1695655 D 189518 CDS NP_711881.1 24214400 1151043 complement(1697073..1697291) 1 NC_004342.2 hypothetical protein 1697291 1151043 LA_1700 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711881.1 1697073 R 189518 CDS NP_711882.1 24214401 1151044 complement(1697377..1698189) 1 NC_004342.2 hypothetical protein 1698189 1151044 LA_1701 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711882.1 1697377 R 189518 CDS NP_711883.1 24214402 1151045 complement(1698274..1699173) 1 NC_004342.2 esterase 1699173 1151045 LA_1702 Leptospira interrogans serovar Lai str. 56601 esterase NP_711883.1 1698274 R 189518 CDS NP_711884.1 24214403 1151046 complement(1699212..1700402) 1 NC_004342.2 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1700402 pgk 1151046 pgk Leptospira interrogans serovar Lai str. 56601 phosphoglycerate kinase NP_711884.1 1699212 R 189518 CDS NP_711885.1 24214404 1151047 complement(1700406..1701413) 1 NC_004342.2 glyceraldehyde 3-phosphate dehydrogenase 1701413 gapA 1151047 gapA Leptospira interrogans serovar Lai str. 56601 glyceraldehyde 3-phosphate dehydrogenase NP_711885.1 1700406 R 189518 CDS NP_711888.1 24214407 1151050 1702271..1702693 1 NC_004342.2 hypothetical protein 1702693 1151050 LA_1707 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711888.1 1702271 D 189518 CDS NP_711890.1 24214409 1151052 complement(1703174..1703596) 1 NC_004342.2 two-component system signal receiver 1703596 1151052 LA_1709 Leptospira interrogans serovar Lai str. 56601 two-component system signal receiver NP_711890.1 1703174 R 189518 CDS NP_711891.1 24214410 1151053 complement(1703601..1704356) 1 NC_004342.2 histidine kinase sensor protein 1704356 1151053 LA_1710 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_711891.1 1703601 R 189518 CDS NP_711892.1 24214411 1151054 complement(1704334..1705056) 1 NC_004342.2 histidine kinase sensor protein 1705056 1151054 LA_1711 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_711892.1 1704334 R 189518 CDS NP_711893.2 294827932 1151055 complement(1705223..1705783) 1 NC_004342.2 signal peptidase I 1705783 1151055 LA_1712 Leptospira interrogans serovar Lai str. 56601 signal peptidase I NP_711893.2 1705223 R 189518 CDS NP_711895.2 294827933 1151057 1705893..1706435 1 NC_004342.2 carbonic anhydrase/acetyltransferase 1706435 paaY 1151057 paaY Leptospira interrogans serovar Lai str. 56601 carbonic anhydrase/acetyltransferase NP_711895.2 1705893 D 189518 CDS NP_711896.1 24214415 1151058 1706719..1707792 1 NC_004342.2 hypothetical protein 1707792 1151058 LA_1715 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711896.1 1706719 D 189518 CDS NP_711900.1 24214419 1151062 1708468..1709397 1 NC_004342.2 cysteine synthase 1709397 cysK 1151062 cysK Leptospira interrogans serovar Lai str. 56601 cysteine synthase NP_711900.1 1708468 D 189518 CDS NP_711902.1 24214421 1151064 1710940..1712781 1 NC_004342.2 DNA topoisomerase 1712781 topA 1151064 topA Leptospira interrogans serovar Lai str. 56601 DNA topoisomerase NP_711902.1 1710940 D 189518 CDS NP_711905.1 24214424 1151067 complement(1713974..1714786) 1 NC_004342.2 ABC transporter ATP-binding protein 1714786 modF 1151067 modF Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_711905.1 1713974 R 189518 CDS NP_711906.1 24214425 1151068 complement(1714783..1716360) 1 NC_004342.2 HD family protein 1716360 1151068 LA_1726 Leptospira interrogans serovar Lai str. 56601 HD family protein NP_711906.1 1714783 R 189518 CDS NP_711907.2 294827934 1151069 1716379..1716636 1 NC_004342.2 hypothetical protein 1716636 1151069 LA_1725 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711907.2 1716379 D 189518 CDS NP_711908.2 294827935 1151070 1716647..1716883 1 NC_004342.2 hypothetical protein 1716883 1151070 LA_1727 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711908.2 1716647 D 189518 CDS NP_711909.1 24214428 1151071 complement(1717352..1718200) 1 NC_004342.2 hypothetical protein 1718200 1151071 LA_1728 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711909.1 1717352 R 189518 CDS NP_711910.2 294827936 1151072 complement(1718290..1718625) 1 NC_004342.2 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 1718625 panD 1151072 panD Leptospira interrogans serovar Lai str. 56601 aspartate alpha-decarboxylase NP_711910.2 1718290 R 189518 CDS NP_711911.1 24214430 1151073 complement(1718652..1719185) 1 NC_004342.2 hypothetical protein 1719185 1151073 LA_1730 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711911.1 1718652 R 189518 CDS NP_711912.1 24214431 1151074 1719198..1719848 1 NC_004342.2 biotin/lipoate protein ligase 1719848 lipB 1151074 lipB Leptospira interrogans serovar Lai str. 56601 biotin/lipoate protein ligase NP_711912.1 1719198 D 189518 CDS NP_711914.1 24214433 1151076 1720277..1721440 1 NC_004342.2 hypothetical protein 1721440 1151076 LA_1733 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711914.1 1720277 D 189518 CDS NP_711915.1 24214434 1151077 1721447..1722379 1 NC_004342.2 anti-sigma factor antagonist-like protein 1722379 1151077 LA_1734 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist-like protein NP_711915.1 1721447 D 189518 CDS NP_711916.1 24214435 1151078 1722383..1723978 1 NC_004342.2 MviN-like protein 1723978 mviN 1151078 mviN Leptospira interrogans serovar Lai str. 56601 MviN-like protein NP_711916.1 1722383 D 189518 CDS NP_711917.1 24214436 1151079 1723988..1724209 1 NC_004342.2 hypothetical protein 1724209 1151079 LA_1736 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711917.1 1723988 D 189518 CDS NP_711918.1 24214437 1151080 1724221..1728837 1 NC_004342.2 hypothetical protein 1728837 1151080 LA_1737 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711918.1 1724221 D 189518 CDS NP_711919.2 294827937 1151081 complement(1728896..1729336) 1 NC_004342.2 transcriptional regulator 1729336 1151081 LA_1738 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711919.2 1728896 R 189518 CDS NP_711920.1 24214439 1151082 1729459..1729824 1 NC_004342.2 hypothetical protein 1729824 1151082 LA_1739 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711920.1 1729459 D 189518 CDS NP_711921.1 24214440 1151083 complement(1730141..1731139) 1 NC_004342.2 hypothetical protein 1731139 1151083 LA_1740 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711921.1 1730141 R 189518 CDS NP_711922.1 24214441 1151084 complement(1731136..1731885) 1 NC_004342.2 acyltransferase 1731885 1151084 LA_1741 Leptospira interrogans serovar Lai str. 56601 acyltransferase NP_711922.1 1731136 R 189518 CDS NP_711924.2 294827938 1151086 1732601..1733515 1 NC_004342.2 methylase of chemotaxis methyl-accepting protein 1733515 cheR 1151086 cheR Leptospira interrogans serovar Lai str. 56601 methylase of chemotaxis methyl-accepting protein NP_711924.2 1732601 D 189518 CDS NP_711925.2 294827939 1151087 1733589..1734119 1 NC_004342.2 chemotaxis-specific methylesterase CheB 1734119 cheB 1151087 cheB Leptospira interrogans serovar Lai str. 56601 chemotaxis-specific methylesterase CheB NP_711925.2 1733589 D 189518 CDS NP_711926.2 294827940 1151088 1734122..1737739 1 NC_004342.2 histidine kinase/response regulator hybrid protein 1737739 1151088 LA_1745 Leptospira interrogans serovar Lai str. 56601 histidine kinase/response regulator hybrid protein NP_711926.2 1734122 D 189518 CDS NP_711927.1 24214446 1151089 1737753..1738868 1 NC_004342.2 two component system sensor histidine kinase\response regulator 1738868 1151089 LA_1746 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase\response regulator NP_711927.1 1737753 D 189518 CDS NP_711928.1 24214447 1151090 complement(1739130..1739675) 1 NC_004342.2 IS1501 transposase 1739675 1151090 LA_1747 Leptospira interrogans serovar Lai str. 56601 IS1501 transposase NP_711928.1 1739130 R 189518 CDS NP_711929.2 294827941 1151091 1739928..1740086 1 NC_004342.2 transposase 1740086 1151091 LA_1748 Leptospira interrogans serovar Lai str. 56601 transposase NP_711929.2 1739928 D 189518 CDS NP_711930.2 294827942 1151092 1740092..1740934 1 NC_004342.2 transposase 1740934 tra5 1151092 tra5 Leptospira interrogans serovar Lai str. 56601 transposase NP_711930.2 1740092 D 189518 CDS NP_711933.1 24214452 1151095 complement(1742210..1742755) 1 NC_004342.2 hypothetical protein 1742755 1151095 LA_1752 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711933.1 1742210 R 189518 CDS NP_711934.2 294827943 1151096 complement(1743554..1743940) 1 NC_004342.2 hypothetical protein 1743940 1151096 LA_1753 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711934.2 1743554 R 189518 CDS NP_711937.1 24214456 1151099 1744597..1745157 1 NC_004342.2 hypothetical protein 1745157 1151099 LA_1756 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711937.1 1744597 D 189518 CDS NP_711938.1 24214457 1151100 1745187..1745819 1 NC_004342.2 hypothetical protein 1745819 1151100 LA_1757 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711938.1 1745187 D 189518 CDS NP_711939.1 24214458 1151101 1745816..1748326 1 NC_004342.2 hypothetical protein 1748326 1151101 LA_1758 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711939.1 1745816 D 189518 CDS NP_711940.2 294827944 1151102 complement(1748632..1750395) 1 NC_004342.2 hypothetical protein 1750395 1151102 LA_1759 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711940.2 1748632 R 189518 CDS NP_711942.2 294827945 1151104 1751554..1751907 1 NC_004342.2 hypothetical protein 1751907 1151104 LA_1761 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711942.2 1751554 D 189518 CDS NP_711943.2 294827946 1151105 1752046..1754013 1 NC_004342.2 hypothetical protein 1754013 1151105 LA_1762 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711943.2 1752046 D 189518 CDS NP_711944.1 24214463 1151106 1754083..1754952 1 NC_004342.2 hypothetical protein 1754952 1151106 LA_1763 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711944.1 1754083 D 189518 CDS NP_711945.2 294827947 1151107 1755036..1756235 1 NC_004342.2 hypothetical protein 1756235 1151107 LA_1764 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711945.2 1755036 D 189518 CDS NP_711946.2 294827948 1151108 1756443..1764086 1 NC_004342.2 cytoplasmic membrane protein 1764086 1151108 LA_1765 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_711946.2 1756443 D 189518 CDS NP_711948.1 24214467 1151110 1764086..1764568 1 NC_004342.2 hypothetical protein 1764568 1151110 LA_1767 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711948.1 1764086 D 189518 CDS NP_711949.1 24214468 1151111 complement(1764776..1765579) 1 NC_004342.2 transposase 1765579 1151111 LA_1768 Leptospira interrogans serovar Lai str. 56601 transposase NP_711949.1 1764776 R 189518 CDS NP_711951.1 24214470 1151113 complement(1765952..1767124) 1 NC_004342.2 transcriptional regulator 1767124 1151113 LA_1770 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_711951.1 1765952 R 189518 CDS NP_711952.2 294827949 1151114 complement(1767143..1767370) 1 NC_004342.2 hypothetical protein 1767370 1151114 LA_1771 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711952.2 1767143 R 189518 CDS NP_711953.2 294827950 1151115 1767627..1768007 1 NC_004342.2 hypothetical protein 1768007 1151115 LA_1772 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711953.2 1767627 D 189518 CDS NP_711954.1 24214473 1151116 complement(1768014..1768913) 1 NC_004342.2 hypothetical protein 1768913 1151116 LA_1773 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711954.1 1768014 R 189518 CDS NP_711955.1 24214474 1151117 complement(1768938..1769558) 1 NC_004342.2 hypothetical protein 1769558 1151117 LA_1774 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711955.1 1768938 R 189518 CDS NP_711956.1 24214475 1151118 1770839..1771315 1 NC_004342.2 hypothetical protein 1771315 1151118 LA_1775 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711956.1 1770839 D 189518 CDS NP_711957.2 294827951 1151119 complement(1771564..1771767) 1 NC_004342.2 hypothetical protein 1771767 1151119 LA_1776 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711957.2 1771564 R 189518 CDS NP_711959.2 294827952 1151121 1772550..1772876 1 NC_004342.2 hypothetical protein 1772876 1151121 LA_1778 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711959.2 1772550 D 189518 CDS NP_711960.1 24214479 1151122 1773189..1773980 1 NC_004342.2 hypothetical protein 1773980 1151122 LA_1779 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711960.1 1773189 D 189518 CDS NP_711961.1 24214480 1151123 1774316..1774552 1 NC_004342.2 transcriptional regulator/antitoxin MazE 1774552 mazE 1151123 mazE Leptospira interrogans serovar Lai str. 56601 transcriptional regulator/antitoxin MazE NP_711961.1 1774316 D 189518 CDS NP_711962.1 24214481 1151124 1774546..1774887 1 NC_004342.2 ppGpp-regulated growth inhibitor ChpA/MazF 1774887 mazF 1151124 mazF Leptospira interrogans serovar Lai str. 56601 ppGpp-regulated growth inhibitor ChpA/MazF NP_711962.1 1774546 D 189518 CDS NP_711963.1 24214482 1151125 complement(1775020..1775337) 1 NC_004342.2 hypothetical protein 1775337 1151125 LA_1782 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711963.1 1775020 R 189518 CDS NP_711964.2 294827953 1151126 complement(1775337..1775603) 1 NC_004342.2 hypothetical protein 1775603 1151126 LA_1783 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711964.2 1775337 R 189518 CDS NP_711967.1 24214486 1151129 complement(1775995..1776660) 1 NC_004342.2 hypothetical protein 1776660 1151129 LA_1786 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711967.1 1775995 R 189518 CDS NP_711970.1 24214489 1151132 1777865..1778326 1 NC_004342.2 hypothetical protein 1778326 1151132 LA_1789 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711970.1 1777865 D 189518 CDS NP_711972.2 294827954 1151134 1778530..1779042 1 NC_004342.2 hypothetical protein 1779042 1151134 LA_1791 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711972.2 1778530 D 189518 CDS NP_711974.1 24214493 1151136 complement(1779630..1780520) 1 NC_004342.2 transposase 1780520 1151136 LA_1793 Leptospira interrogans serovar Lai str. 56601 transposase NP_711974.1 1779630 R 189518 CDS NP_711975.1 24214494 1151137 1781267..1782283 1 NC_004342.2 hypothetical protein 1782283 1151137 LA_1794 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711975.1 1781267 D 189518 CDS NP_711977.1 24214496 1151139 1782790..1783335 1 NC_004342.2 hypothetical protein 1783335 1151139 LA_1796 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711977.1 1782790 D 189518 CDS NP_711978.1 24214497 1151140 complement(1783336..1783533) 1 NC_004342.2 hypothetical protein 1783533 1151140 LA_1797 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711978.1 1783336 R 189518 CDS NP_711979.1 24214498 1151141 1783786..1784085 1 NC_004342.2 Phd-like protein 1784085 1151141 LA_1798 Leptospira interrogans serovar Lai str. 56601 Phd-like protein NP_711979.1 1783786 D 189518 CDS NP_711980.1 24214499 1151142 1784088..1784534 1 NC_004342.2 hypothetical protein 1784534 1151142 LA_1799 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711980.1 1784088 D 189518 CDS NP_711981.2 294827955 1151143 1785125..1785250 1 NC_004342.2 hypothetical protein 1785250 1151143 LA_1800 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711981.2 1785125 D 189518 CDS NP_711984.1 24214503 1151144 1785903..1786142 1 NC_004342.2 hypothetical protein 1786142 1151144 LA_1803 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711984.1 1785903 D 189518 CDS YP_003573312.1 294827956 9006906 1786591..1786920 1 NC_004342.2 acetyltransferase-like protein 1786920 9006906 LA_1803a Leptospira interrogans serovar Lai str. 56601 acetyltransferase-like protein YP_003573312.1 1786591 D 189518 CDS NP_711987.1 24214506 1151149 1787646..1788167 1 NC_004342.2 hypothetical protein 1788167 1151149 LA_1806 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711987.1 1787646 D 189518 CDS NP_711988.2 294827957 1151150 1788214..1788477 1 NC_004342.2 hypothetical protein 1788477 1151150 LA_1807 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711988.2 1788214 D 189518 CDS NP_711989.1 24214508 1151151 complement(1789098..1790000) 1 NC_004342.2 transposase 1790000 1151151 LA_1808 Leptospira interrogans serovar Lai str. 56601 transposase NP_711989.1 1789098 R 189518 CDS YP_003573313.1 294827958 9006907 complement(1790353..1790532) 1 NC_004342.2 hypothetical protein 1790532 9006907 LA_1808a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573313.1 1790353 R 189518 CDS NP_711990.1 24214509 1151152 1791117..1791764 1 NC_004342.2 hypothetical protein 1791764 1151152 LA_1809 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711990.1 1791117 D 189518 CDS NP_711992.2 294827959 1151154 complement(1792350..1793192) 1 NC_004342.2 transposase 1793192 tra5 1151154 tra5 Leptospira interrogans serovar Lai str. 56601 transposase NP_711992.2 1792350 R 189518 CDS NP_711993.2 294827960 1151155 complement(1793198..1793356) 1 NC_004342.2 transposase 1793356 1151155 LA_1812 Leptospira interrogans serovar Lai str. 56601 transposase NP_711993.2 1793198 R 189518 CDS NP_711994.1 24214513 1151156 1793736..1794275 1 NC_004342.2 hypothetical protein 1794275 1151156 LA_1813 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711994.1 1793736 D 189518 CDS YP_003573314.1 294827961 9006908 1794358..1794768 1 NC_004342.2 hypothetical protein 1794768 9006908 LA_1813a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573314.1 1794358 D 189518 CDS NP_711996.1 24214515 1151158 1796285..1796758 1 NC_004342.2 hypothetical protein 1796758 1151158 LA_1815 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711996.1 1796285 D 189518 CDS NP_711998.2 294827962 1151160 1796881..1797126 1 NC_004342.2 hypothetical protein 1797126 1151160 LA_1816 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_711998.2 1796881 D 189518 CDS YP_003573315.1 294827963 9006909 1797104..1797520 1 NC_004342.2 hypothetical protein 1797520 9006909 LA_1816a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573315.1 1797104 D 189518 CDS NP_712001.2 294827964 1151163 complement(1797871..1798008) 1 NC_004342.2 hypothetical protein 1798008 1151163 LA_1820 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712001.2 1797871 R 189518 CDS NP_712002.1 24214521 1151164 1798232..1798780 1 NC_004342.2 serine acetyltransferase 1798780 cysE 1151164 cysE Leptospira interrogans serovar Lai str. 56601 serine acetyltransferase NP_712002.1 1798232 D 189518 CDS NP_712004.1 24214523 1151166 1799254..1800207 1 NC_004342.2 hypothetical protein 1800207 1151166 LA_1823 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712004.1 1799254 D 189518 CDS NP_712005.1 24214524 1151167 1800396..1801322 1 NC_004342.2 hypothetical protein 1801322 1151167 LA_1824 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712005.1 1800396 D 189518 CDS NP_712006.1 24214525 1151168 complement(1801591..1802658) 1 NC_004342.2 hypothetical protein 1802658 1151168 LA_1825 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712006.1 1801591 R 189518 CDS NP_712007.2 294827965 1151169 complement(1803112..1803981) 1 NC_004342.2 hypothetical protein 1803981 1151169 LA_1827 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712007.2 1803112 R 189518 CDS NP_712008.1 24214527 1151170 1803923..1804144 1 NC_004342.2 hypothetical protein 1804144 1151170 LA_1826 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712008.1 1803923 D 189518 CDS NP_712010.1 24214529 1151172 complement(1806411..1806632) 1 NC_004342.2 hypothetical protein 1806632 1151172 LA_1829 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712010.1 1806411 R 189518 CDS NP_712011.2 294827966 1151173 complement(1806629..1807534) 1 NC_004342.2 transposase 1807534 1151173 LA_1830 Leptospira interrogans serovar Lai str. 56601 transposase NP_712011.2 1806629 R 189518 CDS NP_712012.1 24214531 1151174 complement(1807769..1808152) 1 NC_004342.2 hypothetical protein 1808152 1151174 LA_1831 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712012.1 1807769 R 189518 CDS NP_712013.1 24214532 1151175 complement(1808156..1809154) 1 NC_004342.2 hypothetical protein 1809154 1151175 LA_1833 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712013.1 1808156 R 189518 CDS NP_712016.2 294827967 1151178 1809784..1810011 1 NC_004342.2 hypothetical protein 1810011 1151178 LA_1835 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712016.2 1809784 D 189518 CDS NP_712017.1 24214536 1151179 1810221..1810598 1 NC_004342.2 hypothetical protein 1810598 1151179 LA_1836 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712017.1 1810221 D 189518 CDS NP_712018.1 24214537 1151180 1810744..1811475 1 NC_004342.2 ParA 1811475 parA 1151180 parA Leptospira interrogans serovar Lai str. 56601 ParA NP_712018.1 1810744 D 189518 CDS NP_712019.1 24214538 1151181 1811472..1812353 1 NC_004342.2 chromosome-partitioning protein ParB 1812353 spo0J 1151181 spo0J Leptospira interrogans serovar Lai str. 56601 chromosome-partitioning protein ParB NP_712019.1 1811472 D 189518 CDS NP_712020.1 24214539 1151182 1812768..1813913 1 NC_004342.2 hypothetical protein 1813913 1151182 LA_1839 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712020.1 1812768 D 189518 CDS NP_712022.1 24214541 1151184 complement(1814302..1814766) 1 NC_004342.2 hypothetical protein 1814766 1151184 LA_1841 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712022.1 1814302 R 189518 CDS NP_712025.1 24214544 1151187 1816104..1816565 1 NC_004342.2 hypothetical protein 1816565 1151187 LA_1844 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712025.1 1816104 D 189518 CDS NP_712027.1 24214546 1151189 1817155..1817553 1 NC_004342.2 hypothetical protein 1817553 1151189 LA_1846 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712027.1 1817155 D 189518 CDS NP_712028.1 24214547 1151190 1817550..1818035 1 NC_004342.2 hypothetical protein 1818035 1151190 LA_1847 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712028.1 1817550 D 189518 CDS NP_712029.1 24214548 1151191 1818892..1819434 1 NC_004342.2 ISLbp1 transposase 1819434 1151191 LA_1848 Leptospira interrogans serovar Lai str. 56601 ISLbp1 transposase NP_712029.1 1818892 D 189518 CDS NP_712030.1 24214549 1151192 1819431..1819796 1 NC_004342.2 hypothetical protein 1819796 1151192 LA_1849 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712030.1 1819431 D 189518 CDS NP_712031.1 24214550 1151193 1819923..1820057 1 NC_004342.2 ISLbp1 transposase 1820057 1151193 LA_1850 Leptospira interrogans serovar Lai str. 56601 ISLbp1 transposase NP_712031.1 1819923 D 189518 CDS NP_712033.2 294827969 1151195 1821359..1822576 1 NC_004342.2 hypothetical protein 1822576 1151195 LA_1852 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712033.2 1821359 D 189518 CDS NP_712034.1 24214553 1151196 1822702..1823142 1 NC_004342.2 hypothetical protein 1823142 phnB 1151196 phnB Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712034.1 1822702 D 189518 CDS NP_712035.1 24214554 1151197 1823944..1825374 1 NC_004342.2 hypothetical protein 1825374 1151197 LA_1854 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712035.1 1823944 D 189518 CDS NP_712036.1 24214555 1151198 complement(1825375..1826238) 1 NC_004342.2 endoflagellar distal basal body rod protein 1826238 flgG 1151198 flgG Leptospira interrogans serovar Lai str. 56601 endoflagellar distal basal body rod protein NP_712036.1 1825375 R 189518 CDS NP_712038.1 24214557 1151200 complement(1827289..1827726) 1 NC_004342.2 ferric uptake regulator 1827726 fur 1151200 fur Leptospira interrogans serovar Lai str. 56601 ferric uptake regulator NP_712038.1 1827289 R 189518 CDS NP_712039.1 24214558 1151201 1828215..1828760 1 NC_004342.2 ankyrin repeat-containing protein 1828760 arp 1151201 arp Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_712039.1 1828215 D 189518 CDS NP_712040.2 294827970 1151202 1828760..1830205 1 NC_004342.2 catalase 1830205 katE 1151202 katE Leptospira interrogans serovar Lai str. 56601 catalase NP_712040.2 1828760 D 189518 CDS NP_712041.1 24214560 1151203 1830609..1832828 1 NC_004342.2 histidine kinase sensor protein 1832828 1151203 LA_1860 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_712041.1 1830609 D 189518 CDS NP_712042.1 24214561 1151204 complement(1833141..1834271) 1 NC_004342.2 hypothetical protein 1834271 1151204 LA_1861 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712042.1 1833141 R 189518 CDS NP_712043.1 24214562 1151205 complement(1835062..1835724) 1 NC_004342.2 rRNA methylase 1835724 spoU 1151205 spoU Leptospira interrogans serovar Lai str. 56601 rRNA methylase NP_712043.1 1835062 R 189518 CDS NP_712044.1 24214563 1151206 complement(1835814..1837229) 1 NC_004342.2 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1837229 cysS 1151206 cysS Leptospira interrogans serovar Lai str. 56601 cysteinyl-tRNA synthetase NP_712044.1 1835814 R 189518 CDS NP_712045.1 24214564 1151207 complement(1837226..1838191) 1 NC_004342.2 acetyl esterase 1838191 1151207 LA_1864 Leptospira interrogans serovar Lai str. 56601 acetyl esterase NP_712045.1 1837226 R 189518 CDS NP_712046.1 24214565 1151208 complement(1838207..1839061) 1 NC_004342.2 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1839061 folD 1151208 folD Leptospira interrogans serovar Lai str. 56601 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase NP_712046.1 1838207 R 189518 CDS NP_712047.1 24214566 1151209 1839143..1840450 1 NC_004342.2 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1840450 asnC 1151209 asnC Leptospira interrogans serovar Lai str. 56601 asparaginyl-tRNA synthetase NP_712047.1 1839143 D 189518 CDS NP_712048.1 24214567 1151210 1840850..1841641 1 NC_004342.2 hypothetical protein 1841641 1151210 LA_1867 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712048.1 1840850 D 189518 CDS NP_712049.1 24214568 1151211 1842918..1843295 1 NC_004342.2 hypothetical protein 1843295 1151211 LA_1868 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712049.1 1842918 D 189518 CDS NP_712050.2 294827971 1151212 1843250..1843687 1 NC_004342.2 hypothetical protein 1843687 1151212 LA_1869 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712050.2 1843250 D 189518 CDS NP_712051.2 294827972 1151213 1843708..1843920 1 NC_004342.2 hypothetical protein 1843920 1151213 LA_1870 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712051.2 1843708 D 189518 CDS NP_712053.1 24214572 1151215 1844458..1845231 1 NC_004342.2 hypothetical protein 1845231 1151215 LA_1872 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712053.1 1844458 D 189518 CDS NP_712054.1 24214573 1151216 complement(1845266..1845796) 1 NC_004342.2 hypothetical protein 1845796 1151216 LA_1873 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712054.1 1845266 R 189518 CDS NP_712055.2 294827973 1151217 complement(1846611..1847474) 1 NC_004342.2 hypothetical protein 1847474 1151217 LA_1874 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712055.2 1846611 R 189518 CDS NP_712056.1 24214575 1151218 complement(1847509..1849485) 1 NC_004342.2 ATP-dependent helicase 1849485 dinG 1151218 dinG Leptospira interrogans serovar Lai str. 56601 ATP-dependent helicase NP_712056.1 1847509 R 189518 CDS NP_712058.2 294827974 1151220 complement(1849604..1851211) 1 NC_004342.2 sodium-dependent transporter 1851211 1151220 LA_1877 Leptospira interrogans serovar Lai str. 56601 sodium-dependent transporter NP_712058.2 1849604 R 189518 CDS NP_712060.1 24214579 1151222 1851603..1854185 1 NC_004342.2 ATP-dependent protease ClpA 1854185 clpA 1151222 clpA Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease ClpA NP_712060.1 1851603 D 189518 CDS NP_712061.2 294827975 1151223 complement(1854332..1854739) 1 NC_004342.2 transcriptional regulator 1854739 1151223 LA_1880 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_712061.2 1854332 R 189518 CDS NP_712064.1 24214583 1151226 complement(1857093..1858610) 1 NC_004342.2 hypothetical protein 1858610 1151226 LA_1883 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712064.1 1857093 R 189518 CDS NP_712065.1 24214584 1151227 complement(1858629..1858982) 1 NC_004342.2 hypothetical protein 1858982 1151227 LA_1884 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712065.1 1858629 R 189518 CDS NP_712066.2 294827976 1151228 complement(1858979..1859602) 1 NC_004342.2 hypothetical protein 1859602 1151228 LA_1885 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712066.2 1858979 R 189518 CDS NP_712067.1 24214586 1151229 1859647..1859997 1 NC_004342.2 anti-sigma factor antagonist 1859997 1151229 LA_1886 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_712067.1 1859647 D 189518 CDS NP_712068.1 24214587 1151230 1860009..1860767 1 NC_004342.2 hypothetical protein 1860767 1151230 LA_1887 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712068.1 1860009 D 189518 CDS NP_712069.1 24214588 1151231 1860893..1862695 1 NC_004342.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1862695 lepA 1151231 lepA Leptospira interrogans serovar Lai str. 56601 GTP-binding protein LepA NP_712069.1 1860893 D 189518 CDS NP_712070.1 24214589 1151232 1863025..1863966 1 NC_004342.2 1-aminocyclopropane-1-carboxylate deaminase 1863966 1151232 LA_1889 Leptospira interrogans serovar Lai str. 56601 1-aminocyclopropane-1-carboxylate deaminase NP_712070.1 1863025 D 189518 CDS NP_712071.1 24214590 1151233 1864858..1865583 1 NC_004342.2 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1865583 lpxD 1151233 lpxD Leptospira interrogans serovar Lai str. 56601 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_712071.1 1864858 D 189518 CDS NP_712073.1 24214592 1151235 complement(1866281..1867009) 1 NC_004342.2 hypothetical protein 1867009 1151235 LA_1892 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712073.1 1866281 R 189518 CDS NP_712075.2 294827977 1151237 1867192..1867626 1 NC_004342.2 hypothetical protein 1867626 1151237 LA_1894 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712075.2 1867192 D 189518 CDS NP_712077.1 24214596 1151239 complement(1868029..1868760) 1 NC_004342.2 succinate dehydrogenase/fumarate reductase iron-sulfur subunit 1868760 1151239 LA_1896 Leptospira interrogans serovar Lai str. 56601 succinate dehydrogenase/fumarate reductase iron-sulfur subunit NP_712077.1 1868029 R 189518 CDS NP_712078.1 24214597 1151240 complement(1868760..1870673) 1 NC_004342.2 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1870673 sdhA 1151240 sdhA Leptospira interrogans serovar Lai str. 56601 succinate dehydrogenase flavoprotein subunit NP_712078.1 1868760 R 189518 CDS NP_712079.1 24214598 1151241 complement(1870692..1871372) 1 NC_004342.2 succinate:quinone oxidoreductase (SQR)-like protein 1871372 1151241 LA_1898 Leptospira interrogans serovar Lai str. 56601 succinate:quinone oxidoreductase (SQR)-like protein NP_712079.1 1870692 R 189518 CDS NP_712080.1 24214599 1151242 1871645..1873171 1 NC_004342.2 aldo/keto reductase 1873171 1151242 LA_1899 Leptospira interrogans serovar Lai str. 56601 aldo/keto reductase NP_712080.1 1871645 D 189518 CDS NP_712081.1 24214600 1151243 1873161..1873625 1 NC_004342.2 hypothetical protein 1873625 1151243 LA_1900 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712081.1 1873161 D 189518 CDS NP_712085.1 24214604 1151247 1875071..1875919 1 NC_004342.2 hypothetical protein 1875919 1151247 LA_1904 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712085.1 1875071 D 189518 CDS NP_712086.1 24214605 1151248 1875929..1877266 1 NC_004342.2 hypothetical protein 1877266 1151248 LA_1905 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712086.1 1875929 D 189518 CDS NP_712087.1 24214606 1151249 1877351..1877566 1 NC_004342.2 hypothetical protein 1877566 1151249 LA_1906 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712087.1 1877351 D 189518 CDS NP_712089.2 294827978 1151251 complement(1877949..1878377) 1 NC_004342.2 PaaI thioesterase 1878377 1151251 LA_1908 Leptospira interrogans serovar Lai str. 56601 PaaI thioesterase NP_712089.2 1877949 R 189518 CDS NP_712091.1 24214610 1151253 complement(1879237..1879542) 1 NC_004342.2 hypothetical protein 1879542 1151253 LA_1910 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712091.1 1879237 R 189518 CDS NP_712092.1 24214611 1151254 complement(1879702..1880937) 1 NC_004342.2 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1880937 serA 1151254 serA Leptospira interrogans serovar Lai str. 56601 D-3-phosphoglycerate dehydrogenase NP_712092.1 1879702 R 189518 CDS NP_712093.1 24214612 1151255 1881142..1881678 1 NC_004342.2 hypothetical protein 1881678 1151255 LA_1912 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712093.1 1881142 D 189518 CDS NP_712096.1 24214615 1151258 complement(1882219..1885818) 1 NC_004342.2 TPR-repeat-containing protein 1885818 1151258 LA_1915 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_712096.1 1882219 R 189518 CDS NP_712097.1 24214616 1151259 1885972..1886880 1 NC_004342.2 hypothetical protein 1886880 1151259 LA_1916 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712097.1 1885972 D 189518 CDS NP_712098.1 24214617 1151260 1886927..1887664 1 NC_004342.2 hypothetical protein 1887664 1151260 LA_1917 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712098.1 1886927 D 189518 CDS NP_712099.1 24214618 1151261 1887869..1888138 1 NC_004342.2 hypothetical protein 1888138 1151261 LA_1918 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712099.1 1887869 D 189518 CDS NP_712100.1 24214619 1151262 complement(1888312..1889907) 1 NC_004342.2 DNA-binding transcriptional activator 1889907 1151262 LA_1919 Leptospira interrogans serovar Lai str. 56601 DNA-binding transcriptional activator NP_712100.1 1888312 R 189518 CDS NP_712101.1 24214620 1151263 1891384..1891659 1 NC_004342.2 RNA-binding protein 1891659 1151263 LA_1920 Leptospira interrogans serovar Lai str. 56601 RNA-binding protein NP_712101.1 1891384 D 189518 CDS NP_712104.2 294827979 1151266 1892446..1893243 1 NC_004342.2 hypothetical protein 1893243 1151266 LA_1922 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712104.2 1892446 D 189518 CDS NP_712105.1 24214624 1151267 complement(1894256..1895350) 1 NC_004342.2 hypothetical protein 1895350 1151267 LA_1924 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712105.1 1894256 R 189518 CDS NP_712106.1 24214625 1151268 complement(1895352..1896152) 1 NC_004342.2 sec-independent protein translocase 1896152 tatC 1151268 tatC Leptospira interrogans serovar Lai str. 56601 sec-independent protein translocase NP_712106.1 1895352 R 189518 CDS NP_712107.2 294827980 1151269 complement(1896149..1896406) 1 NC_004342.2 sec-independent protein translocase 1896406 tatA 1151269 tatA Leptospira interrogans serovar Lai str. 56601 sec-independent protein translocase NP_712107.2 1896149 R 189518 CDS NP_712108.1 24214627 1151270 1896810..1897619 1 NC_004342.2 hypothetical protein 1897619 1151270 LA_1927 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712108.1 1896810 D 189518 CDS NP_712109.1 24214628 1151271 1897625..1897984 1 NC_004342.2 thioredoxin 1897984 1151271 LA_1928 Leptospira interrogans serovar Lai str. 56601 thioredoxin NP_712109.1 1897625 D 189518 CDS NP_712110.1 24214629 1151272 1898007..1900166 1 NC_004342.2 CAP family transcription factor 1900166 1151272 LA_1929 Leptospira interrogans serovar Lai str. 56601 CAP family transcription factor NP_712110.1 1898007 D 189518 CDS NP_712111.1 24214630 1151273 1900184..1901314 1 NC_004342.2 acyl-CoA dehydrogenase 1901314 caiA 1151273 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_712111.1 1900184 D 189518 CDS NP_712112.1 24214631 1151274 1901354..1902532 1 NC_004342.2 hypothetical protein 1902532 1151274 LA_1931 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712112.1 1901354 D 189518 CDS NP_712113.1 24214632 1151275 1902638..1903249 1 NC_004342.2 hypothetical protein 1903249 1151275 LA_1932 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712113.1 1902638 D 189518 CDS NP_712114.1 24214633 1151276 complement(1903969..1905306) 1 NC_004342.2 MFS transporter permease 1905306 1151276 LA_1933 Leptospira interrogans serovar Lai str. 56601 MFS transporter permease NP_712114.1 1903969 R 189518 CDS NP_712115.1 24214634 1151277 complement(1905349..1905750) 1 NC_004342.2 hypothetical protein 1905750 1151277 LA_1934 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712115.1 1905349 R 189518 CDS NP_712116.1 24214635 1151278 complement(1905794..1906366) 1 NC_004342.2 hypothetical protein 1906366 1151278 LA_1935 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712116.1 1905794 R 189518 CDS NP_712117.1 24214636 1151279 complement(1906426..1908297) 1 NC_004342.2 hydrolase/acyltransferase 1908297 1151279 LA_1936 Leptospira interrogans serovar Lai str. 56601 hydrolase/acyltransferase NP_712117.1 1906426 R 189518 CDS NP_712118.2 294827981 1151280 complement(1909643..1910179) 1 NC_004342.2 CopG-like transcriptional regulator 1910179 1151280 LA_1937 Leptospira interrogans serovar Lai str. 56601 CopG-like transcriptional regulator NP_712118.2 1909643 R 189518 CDS YP_003573316.1 294827982 9006911 1911024..1911152 1 NC_004342.2 IS1501 transposase 1911152 9006911 LA_1937a Leptospira interrogans serovar Lai str. 56601 IS1501 transposase YP_003573316.1 1911024 D 189518 CDS NP_712120.1 24214639 1151282 complement(1911321..1911800) 1 NC_004342.2 hypothetical protein 1911800 1151282 LA_1939 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712120.1 1911321 R 189518 CDS NP_712122.1 24214641 1151284 complement(1912529..1912930) 1 NC_004342.2 hypothetical protein 1912930 1151284 LA_1941 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712122.1 1912529 R 189518 CDS NP_712123.1 24214642 1151285 complement(1913252..1913596) 1 NC_004342.2 hypothetical protein 1913596 1151285 LA_1942 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712123.1 1913252 R 189518 CDS NP_712125.2 294827983 1151287 complement(1914155..1914331) 1 NC_004342.2 transposase 1914331 1151287 LA_1944 Leptospira interrogans serovar Lai str. 56601 transposase NP_712125.2 1914155 R 189518 CDS NP_712126.2 294827984 1151288 complement(1914766..1915332) 1 NC_004342.2 hypothetical protein 1915332 1151288 LA_1945 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712126.2 1914766 R 189518 CDS NP_712127.1 24214646 1151289 complement(1915316..1915825) 1 NC_004342.2 hypothetical protein 1915825 1151289 LA_1946 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712127.1 1915316 R 189518 CDS NP_712128.1 24214647 1151290 complement(1915830..1917038) 1 NC_004342.2 hypothetical protein 1917038 1151290 LA_1947 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712128.1 1915830 R 189518 CDS NP_712129.1 24214648 1151291 complement(1917055..1917543) 1 NC_004342.2 two-component response regulator receiver protein 1917543 1151291 LA_1948 Leptospira interrogans serovar Lai str. 56601 two-component response regulator receiver protein NP_712129.1 1917055 R 189518 CDS NP_712130.1 24214649 1151292 complement(1917614..1918726) 1 NC_004342.2 hypothetical protein 1918726 1151292 LA_1949 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712130.1 1917614 R 189518 CDS NP_712131.2 294827985 1151293 complement(1918990..1919481) 1 NC_004342.2 hypothetical protein 1919481 1151293 LA_1950 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712131.2 1918990 R 189518 CDS NP_712132.1 24214651 1151294 1920220..1921518 1 NC_004342.2 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1921518 eno 1151294 eno Leptospira interrogans serovar Lai str. 56601 phosphopyruvate hydratase NP_712132.1 1920220 D 189518 CDS YP_003573317.1 294827986 9006913 1921823..1922281 1 NC_004342.2 hypothetical protein 1922281 9006913 LA_1951a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573317.1 1921823 D 189518 CDS NP_712134.2 161484953 1151296 1922292..1922885 1 NC_004342.2 ATP-dependent protease ClpP 1922885 clpP 1151296 clpP Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease ClpP NP_712134.2 1922292 D 189518 CDS NP_712135.1 24214654 1151297 1922899..1923255 1 NC_004342.2 hypothetical protein 1923255 1151297 LA_1954 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712135.1 1922899 D 189518 CDS NP_712136.1 24214655 1151298 1923279..1924289 1 NC_004342.2 alpha-beta hydrolase family esterase 1924289 1151298 LA_1955 Leptospira interrogans serovar Lai str. 56601 alpha-beta hydrolase family esterase NP_712136.1 1923279 D 189518 CDS NP_712137.1 24214656 1151299 1924300..1924857 1 NC_004342.2 hypothetical protein 1924857 1151299 LA_1956 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712137.1 1924300 D 189518 CDS NP_712138.1 24214657 1151300 1924832..1925407 1 NC_004342.2 hypothetical protein 1925407 1151300 LA_1957 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712138.1 1924832 D 189518 CDS NP_712139.2 294827987 1151301 1925631..1926242 1 NC_004342.2 hypothetical protein 1926242 1151301 LA_1958 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712139.2 1925631 D 189518 CDS NP_712140.1 24214659 1151302 1926239..1926988 1 NC_004342.2 bifunctional GMP synthase/glutamine amidotransferase 1926988 guaA 1151302 guaA Leptospira interrogans serovar Lai str. 56601 bifunctional GMP synthase/glutamine amidotransferase NP_712140.1 1926239 D 189518 CDS NP_712141.2 294827988 1151303 1927099..1929825 1 NC_004342.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1929825 secA 1151303 secA Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit SecA NP_712141.2 1927099 D 189518 CDS NP_712142.1 24214661 1151304 1929849..1930286 1 NC_004342.2 hypothetical protein 1930286 1151304 LA_1961 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712142.1 1929849 D 189518 CDS NP_712143.1 24214662 1151305 1930387..1930764 1 NC_004342.2 hypothetical protein 1930764 1151305 LA_1962 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712143.1 1930387 D 189518 CDS NP_712144.2 294827989 1151306 1930912..1932318 1 NC_004342.2 outer membrane efflux protein 1932318 1151306 LA_1963 Leptospira interrogans serovar Lai str. 56601 outer membrane efflux protein NP_712144.2 1930912 D 189518 CDS YP_003573318.1 294827990 9006914 1932329..1933030 1 NC_004342.2 multidrug efflux pump 1933030 9006914 LA_1963a Leptospira interrogans serovar Lai str. 56601 multidrug efflux pump YP_003573318.1 1932329 D 189518 CDS NP_712145.2 294827991 1151307 1933023..1933337 1 NC_004342.2 multidrug efflux pump 1933337 1151307 LA_1964 Leptospira interrogans serovar Lai str. 56601 multidrug efflux pump NP_712145.2 1933023 D 189518 CDS NP_712146.2 294827992 1151308 1933339..1934073 1 NC_004342.2 hypothetical protein 1934073 1151308 LA_1965 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712146.2 1933339 D 189518 CDS NP_712147.2 294827993 1151309 1934079..1937408 1 NC_004342.2 cation efflux system protein 1937408 1151309 LA_1966 Leptospira interrogans serovar Lai str. 56601 cation efflux system protein NP_712147.2 1934079 D 189518 CDS NP_712148.1 24214667 1151310 1937943..1941263 1 NC_004342.2 cation efflux system protein 1941263 1151310 LA_1967 Leptospira interrogans serovar Lai str. 56601 cation efflux system protein NP_712148.1 1937943 D 189518 CDS NP_712149.2 294827994 1151311 complement(1941792..1943444) 1 NC_004342.2 hypothetical protein 1943444 1151311 LA_1968 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712149.2 1941792 R 189518 CDS NP_712151.1 24214670 1151313 complement(1944864..1946162) 1 NC_004342.2 tRNA nucleotidyltransferase/poly A polymerase 1946162 pcnB 1151313 pcnB Leptospira interrogans serovar Lai str. 56601 tRNA nucleotidyltransferase/poly A polymerase NP_712151.1 1944864 R 189518 CDS NP_712152.1 24214671 1151314 complement(1946155..1946556) 1 NC_004342.2 hypothetical protein 1946556 1151314 LA_1971 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712152.1 1946155 R 189518 CDS NP_712153.1 24214672 1151315 complement(1946902..1947291) 1 NC_004342.2 ribonuclease H I 1947291 rnhA 1151315 rnhA Leptospira interrogans serovar Lai str. 56601 ribonuclease H I NP_712153.1 1946902 R 189518 CDS NP_712154.1 24214673 1151316 complement(1947288..1947605) 1 NC_004342.2 hypothetical protein 1947605 1151316 LA_1973 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712154.1 1947288 R 189518 CDS NP_712155.1 24214674 1151317 1947989..1948762 1 NC_004342.2 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 1948762 1151317 LA_1974 Leptospira interrogans serovar Lai str. 56601 arginyl-tRNA-protein transferase NP_712155.1 1947989 D 189518 CDS NP_712157.1 24214676 1151319 1948823..1949563 1 NC_004342.2 short-chain dehydrogenase 1949563 1151319 LA_1975 Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_712157.1 1948823 D 189518 CDS NP_712158.1 24214677 1151320 1949582..1951084 1 NC_004342.2 FAD-binding oxidoreductase 1951084 1151320 LA_1977 Leptospira interrogans serovar Lai str. 56601 FAD-binding oxidoreductase NP_712158.1 1949582 D 189518 CDS NP_712159.1 24214678 1151321 1951085..1952566 1 NC_004342.2 hypothetical protein 1952566 1151321 LA_1978 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712159.1 1951085 D 189518 CDS NP_712160.1 24214679 1151322 1952585..1953718 1 NC_004342.2 glycosyltransferase 1953718 1151322 LA_1979 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_712160.1 1952585 D 189518 CDS NP_712161.2 294827995 1151323 1954084..1954737 1 NC_004342.2 hypothetical protein 1954737 1151323 LA_1980 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712161.2 1954084 D 189518 CDS NP_712162.1 24214681 1151324 complement(1955578..1957200) 1 NC_004342.2 hypothetical protein 1957200 1151324 LA_1981 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712162.1 1955578 R 189518 CDS NP_712163.1 24214682 1151325 complement(1957204..1959189) 1 NC_004342.2 O-antigen polymerase-like protein 1959189 1151325 LA_1982 Leptospira interrogans serovar Lai str. 56601 O-antigen polymerase-like protein NP_712163.1 1957204 R 189518 CDS NP_712164.2 294827996 1151326 complement(1959300..1961051) 1 NC_004342.2 hypothetical protein 1961051 1151326 LA_1984 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712164.2 1959300 R 189518 CDS NP_712165.1 24214684 1151327 1961099..1962373 1 NC_004342.2 signal transduction protein 1962373 rtn 1151327 rtn Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_712165.1 1961099 D 189518 CDS NP_712166.1 24214685 1151328 complement(1963638..1964750) 1 NC_004342.2 hypothetical protein 1964750 1151328 LA_1985 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712166.1 1963638 R 189518 CDS NP_712167.1 24214686 1151329 1964821..1966347 1 NC_004342.2 inosine-5'-monophosphate dehydrogenase 1966347 1151329 LA_1986 Leptospira interrogans serovar Lai str. 56601 inosine-5'-monophosphate dehydrogenase NP_712167.1 1964821 D 189518 CDS NP_712168.1 24214687 1151330 1966348..1967130 1 NC_004342.2 hypothetical protein 1967130 1151330 LA_1987 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712168.1 1966348 D 189518 CDS NP_712169.1 24214688 1151331 1967139..1967831 1 NC_004342.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1967831 1151331 LA_1988 Leptospira interrogans serovar Lai str. 56601 16S ribosomal RNA methyltransferase RsmE NP_712169.1 1967139 D 189518 CDS NP_712170.1 24214689 1151332 complement(1967821..1968105) 1 NC_004342.2 hypothetical protein 1968105 1151332 LA_1989 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712170.1 1967821 R 189518 CDS NP_712172.1 24214691 1151334 1968681..1969325 1 NC_004342.2 thiamine phosphate pyrophosphorylase 1969325 thiE 1151334 thiE Leptospira interrogans serovar Lai str. 56601 thiamine phosphate pyrophosphorylase NP_712172.1 1968681 D 189518 CDS NP_712173.1 24214692 1151335 1969380..1970207 1 NC_004342.2 glycosyltransferase 1970207 wecG 1151335 wecG Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_712173.1 1969380 D 189518 CDS NP_712176.1 24214695 1151338 complement(1971231..1972718) 1 NC_004342.2 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1972718 lysS 1151338 lysS Leptospira interrogans serovar Lai str. 56601 lysyl-tRNA synthetase NP_712176.1 1971231 R 189518 CDS NP_712177.1 24214696 1151339 complement(1972727..1973377) 1 NC_004342.2 hypothetical protein 1973377 1151339 LA_1996 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712177.1 1972727 R 189518 CDS NP_712178.1 24214697 1151340 complement(1973427..1975607) 1 NC_004342.2 glycosyltransferase 1975607 1151340 LA_1997 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_712178.1 1973427 R 189518 CDS NP_712179.1 24214698 1151341 complement(1975818..1976720) 1 NC_004342.2 polysaccharide deacetylase 1976720 1151341 LA_1998 Leptospira interrogans serovar Lai str. 56601 polysaccharide deacetylase NP_712179.1 1975818 R 189518 CDS NP_712180.2 294827997 1151342 complement(1976741..1977247) 1 NC_004342.2 hypothetical protein 1977247 1151342 LA_1999 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712180.2 1976741 R 189518 CDS NP_712182.1 24214701 1151344 complement(1978084..1978758) 1 NC_004342.2 CDP-diacylglycerol--glycerol-3-phosphate 3- phosphatidyltransferase 1978758 pgsA 1151344 pgsA Leptospira interrogans serovar Lai str. 56601 CDP-diacylglycerol--glycerol-3-phosphate 3- phosphatidyltransferase NP_712182.1 1978084 R 189518 CDS NP_712184.1 24214703 1151346 1980400..1981644 1 NC_004342.2 hypothetical protein 1981644 1151346 LA_2003 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712184.1 1980400 D 189518 CDS NP_712185.1 24214704 1151347 1981641..1982501 1 NC_004342.2 hypothetical protein 1982501 1151347 LA_2004 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712185.1 1981641 D 189518 CDS YP_003573319.1 294827998 9006917 1982860..1983054 1 NC_004342.2 hypothetical protein 1983054 9006917 LA_2004a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573319.1 1982860 D 189518 CDS NP_712187.2 294827999 1151349 complement(1983144..1983365) 1 NC_004342.2 hypothetical protein 1983365 1151349 LA_2006 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712187.2 1983144 R 189518 CDS NP_712188.1 24214707 1151350 complement(1983644..1984663) 1 NC_004342.2 flagellar switch complex protein 1984663 fliG 1151350 fliG Leptospira interrogans serovar Lai str. 56601 flagellar switch complex protein NP_712188.1 1983644 R 189518 CDS NP_712189.1 24214708 1151351 complement(1984669..1986045) 1 NC_004342.2 dihydrolipoamide acetyltransferase 1986045 aceF 1151351 aceF Leptospira interrogans serovar Lai str. 56601 dihydrolipoamide acetyltransferase NP_712189.1 1984669 R 189518 CDS NP_712190.1 24214709 1151352 complement(1986067..1987041) 1 NC_004342.2 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 1987041 acoB 1151352 acoB Leptospira interrogans serovar Lai str. 56601 pyruvate dehydrogenase subunit beta NP_712190.1 1986067 R 189518 CDS NP_712191.1 24214710 1151353 complement(1987041..1988024) 1 NC_004342.2 pyruvate dehydrogenase subunit alpha 1988024 acoA 1151353 acoA Leptospira interrogans serovar Lai str. 56601 pyruvate dehydrogenase subunit alpha NP_712191.1 1987041 R 189518 CDS NP_712192.1 24214711 1151354 1988122..1988844 1 NC_004342.2 response regulator containing a signal receiver domain and a DNA/RNA polymerase-binding domain 1988844 1151354 LA_2011 Leptospira interrogans serovar Lai str. 56601 response regulator containing a signal receiver domain and a DNA/RNA polymerase-binding domain NP_712192.1 1988122 D 189518 CDS NP_712193.1 24214712 1151355 1988942..1990267 1 NC_004342.2 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 1990267 1151355 LA_2012 Leptospira interrogans serovar Lai str. 56601 sensory histidine kinase CreC NP_712193.1 1988942 D 189518 CDS NP_712194.1 24214713 1151356 1990537..1990752 1 NC_004342.2 hypothetical protein 1990752 1151356 LA_2013 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712194.1 1990537 D 189518 CDS NP_712195.1 24214714 1151357 1990740..1992116 1 NC_004342.2 hypothetical protein 1992116 creD 1151357 creD Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712195.1 1990740 D 189518 CDS NP_712197.2 294828000 1151359 1992784..1993122 1 NC_004342.2 hypothetical protein 1993122 1151359 LA_2016 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712197.2 1992784 D 189518 CDS NP_712198.1 24214717 1151360 1993910..1994755 1 NC_004342.2 endoflagellar filament core protein 1994755 1151360 LA_2017 Leptospira interrogans serovar Lai str. 56601 endoflagellar filament core protein NP_712198.1 1993910 D 189518 CDS NP_712200.1 24214719 1151362 1995213..1996064 1 NC_004342.2 flagellin protein 1996064 1151362 LA_2019 Leptospira interrogans serovar Lai str. 56601 flagellin protein NP_712200.1 1995213 D 189518 CDS NP_712201.2 294828001 1151363 1997115..1998416 1 NC_004342.2 hypothetical protein 1998416 1151363 LA_2020 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712201.2 1997115 D 189518 CDS NP_712203.1 24214722 1151365 complement(1998555..1999046) 1 NC_004342.2 hypothetical protein 1999046 1151365 LA_2022 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712203.1 1998555 R 189518 CDS NP_712204.2 294828002 1151366 complement(1999132..1999566) 1 NC_004342.2 hypothetical protein 1999566 1151366 LA_2023 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712204.2 1999132 R 189518 CDS NP_712205.1 24214724 1151367 complement(2000348..2001586) 1 NC_004342.2 hypothetical protein 2001586 1151367 LA_2024 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712205.1 2000348 R 189518 CDS NP_712206.2 294828003 1151368 2001652..2002914 1 NC_004342.2 hypothetical protein 2002914 1151368 LA_2025 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712206.2 2001652 D 189518 CDS NP_712207.2 294828004 1151369 2002883..2003545 1 NC_004342.2 hypothetical protein 2003545 1151369 LA_2026 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712207.2 2002883 D 189518 CDS NP_712208.1 24214727 1151370 2003542..2004393 1 NC_004342.2 hypothetical protein 2004393 1151370 LA_2027 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712208.1 2003542 D 189518 CDS NP_712209.1 24214728 1151371 2004717..2005463 1 NC_004342.2 stomatin-like protein 2005463 1151371 LA_2028 Leptospira interrogans serovar Lai str. 56601 stomatin-like protein NP_712209.1 2004717 D 189518 CDS NP_712211.2 294828005 1151373 2005689..2006531 1 NC_004342.2 hypothetical protein 2006531 1151373 LA_2030 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712211.2 2005689 D 189518 CDS NP_712212.2 294828006 1151374 2006616..2007269 1 NC_004342.2 hypothetical protein 2007269 1151374 LA_2031 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712212.2 2006616 D 189518 CDS NP_712213.2 294828007 1151375 complement(2007706..2008242) 1 NC_004342.2 CopG-like transcriptional regulator 2008242 1151375 LA_2032 Leptospira interrogans serovar Lai str. 56601 CopG-like transcriptional regulator NP_712213.2 2007706 R 189518 CDS NP_712215.1 24214734 1151377 complement(2009937..2010473) 1 NC_004342.2 hypothetical protein 2010473 1151377 LA_2035 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712215.1 2009937 R 189518 CDS NP_712216.2 294828008 1151378 2010496..2011695 1 NC_004342.2 hydrolase 2011695 1151378 LA_2034 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_712216.2 2010496 D 189518 CDS NP_712217.1 24214736 1151379 2011970..2012638 1 NC_004342.2 hypothetical protein 2012638 1151379 LA_2036 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712217.1 2011970 D 189518 CDS NP_712221.1 24214740 1151383 complement(2013584..2014333) 1 NC_004342.2 periplasmic solute-binding protein 2014333 1151383 LA_2040 Leptospira interrogans serovar Lai str. 56601 periplasmic solute-binding protein NP_712221.1 2013584 R 189518 CDS NP_712222.1 24214741 1151384 complement(2014330..2014605) 1 NC_004342.2 hypothetical protein 2014605 1151384 LA_2041 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712222.1 2014330 R 189518 CDS NP_712223.1 24214742 1151385 2014755..2015666 1 NC_004342.2 methylase of chemotaxis methyl-accepting protein 2015666 cheR 1151385 cheR Leptospira interrogans serovar Lai str. 56601 methylase of chemotaxis methyl-accepting protein NP_712223.1 2014755 D 189518 CDS NP_712225.2 294828009 1151387 complement(2016149..2016670) 1 NC_004342.2 HIT family hydrolase 2016670 hit 1151387 hit Leptospira interrogans serovar Lai str. 56601 HIT family hydrolase NP_712225.2 2016149 R 189518 CDS NP_712226.1 24214745 1151388 2016960..2017964 1 NC_004342.2 S-adenosyl-methyltransferase 2017964 1151388 LA_2045 Leptospira interrogans serovar Lai str. 56601 S-adenosyl-methyltransferase NP_712226.1 2016960 D 189518 CDS NP_712227.1 24214746 1151389 2017971..2018333 1 NC_004342.2 hypothetical protein 2018333 1151389 LA_2046 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712227.1 2017971 D 189518 CDS NP_712228.2 294828010 1151390 2018308..2019822 1 NC_004342.2 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase 2019822 murE 1151390 murE Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase NP_712228.2 2018308 D 189518 CDS NP_712229.2 294828011 1151391 2019960..2020985 1 NC_004342.2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2020985 mraY 1151391 mraY Leptospira interrogans serovar Lai str. 56601 phospho-N-acetylmuramoyl-pentapeptide- transferase NP_712229.2 2019960 D 189518 CDS NP_712230.2 294828012 1151392 2020982..2022136 1 NC_004342.2 cell division protein 2022136 ftsW 1151392 ftsW Leptospira interrogans serovar Lai str. 56601 cell division protein NP_712230.2 2020982 D 189518 CDS NP_712231.1 24214750 1151393 2022133..2023209 1 NC_004342.2 UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 2023209 murG 1151393 murG Leptospira interrogans serovar Lai str. 56601 UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_712231.1 2022133 D 189518 CDS NP_712232.2 294828013 1151394 2023212..2024678 1 NC_004342.2 UDP-N-acetylmuramate--L-alanine ligase 2024678 murC 1151394 murC Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylmuramate--L-alanine ligase NP_712232.2 2023212 D 189518 CDS NP_712233.1 24214752 1151395 2024779..2025978 1 NC_004342.2 hypothetical protein 2025978 1151395 LA_2052 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712233.1 2024779 D 189518 CDS NP_712234.1 24214753 1151396 2025975..2026523 1 NC_004342.2 hypothetical protein 2026523 1151396 LA_2053 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712234.1 2025975 D 189518 CDS NP_712235.2 294828014 1151397 complement(2026483..2027319) 1 NC_004342.2 3-hydroxyisobutyrate dehydrogenase 2027319 mmsB 1151397 mmsB Leptospira interrogans serovar Lai str. 56601 3-hydroxyisobutyrate dehydrogenase NP_712235.2 2026483 R 189518 CDS NP_712236.2 294828015 1151398 complement(2027479..2028228) 1 NC_004342.2 MCE-like protein 2028228 1151398 LA_2055 Leptospira interrogans serovar Lai str. 56601 MCE-like protein NP_712236.2 2027479 R 189518 CDS NP_712237.1 24214756 1151399 complement(2028258..2029025) 1 NC_004342.2 ABC transporter ATP-binding protein 2029025 ttg2A 1151399 ttg2A Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_712237.1 2028258 R 189518 CDS NP_712238.1 24214757 1151400 complement(2029029..2029808) 1 NC_004342.2 ABC transporter membrane protein 2029808 ttg2B 1151400 ttg2B Leptospira interrogans serovar Lai str. 56601 ABC transporter membrane protein NP_712238.1 2029029 R 189518 CDS NP_712239.2 294828016 1151401 complement(2029805..2031124) 1 NC_004342.2 hypothetical protein 2031124 1151401 LA_2059 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712239.2 2029805 R 189518 CDS NP_712240.1 24214759 1151402 2031215..2032270 1 NC_004342.2 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 2032270 ddlA 1151402 ddlA Leptospira interrogans serovar Lai str. 56601 D-alanyl-alanine synthetase A NP_712240.1 2031215 D 189518 CDS NP_712241.1 24214760 1151403 complement(2032275..2032892) 1 NC_004342.2 methyltransferase 2032892 1151403 LA_2060 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_712241.1 2032275 R 189518 CDS NP_712242.1 24214761 1151404 complement(2032896..2033996) 1 NC_004342.2 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 2033996 metX 1151404 metX Leptospira interrogans serovar Lai str. 56601 homoserine O-acetyltransferase NP_712242.1 2032896 R 189518 CDS NP_712243.1 24214762 1151405 complement(2034255..2035559) 1 NC_004342.2 O-acetylhomoserine/O-acetylserine sulfhydrylase 2035559 met17 1151405 met17 Leptospira interrogans serovar Lai str. 56601 O-acetylhomoserine/O-acetylserine sulfhydrylase NP_712243.1 2034255 R 189518 CDS NP_712244.1 24214763 1151406 2035859..2037502 1 NC_004342.2 cytoplasmic membrane protein 2037502 1151406 LA_2063 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_712244.1 2035859 D 189518 CDS NP_712245.1 24214764 1151407 complement(2037499..2038275) 1 NC_004342.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2038275 1151407 LA_2064 Leptospira interrogans serovar Lai str. 56601 16S ribosomal RNA methyltransferase RsmE NP_712245.1 2037499 R 189518 CDS NP_712246.2 294828017 1151408 complement(2038288..2038674) 1 NC_004342.2 hypothetical protein 2038674 1151408 LA_2065 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712246.2 2038288 R 189518 CDS NP_712247.1 24214766 1151409 complement(2038735..2039565) 1 NC_004342.2 hypothetical protein 2039565 1151409 LA_2066 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712247.1 2038735 R 189518 CDS NP_712248.1 24214767 1151410 complement(2039693..2040979) 1 NC_004342.2 ATPase AAA 2040979 spoVK 1151410 spoVK Leptospira interrogans serovar Lai str. 56601 ATPase AAA NP_712248.1 2039693 R 189518 CDS NP_712250.2 294828018 1151412 2041076..2041612 1 NC_004342.2 flagellar motor switch protein 2041612 fliN 1151412 fliN Leptospira interrogans serovar Lai str. 56601 flagellar motor switch protein NP_712250.2 2041076 D 189518 CDS NP_712252.1 24214771 1151414 complement(2042087..2043019) 1 NC_004342.2 HflC membrane associated protease 2043019 hflC 1151414 hflC Leptospira interrogans serovar Lai str. 56601 HflC membrane associated protease NP_712252.1 2042087 R 189518 CDS NP_712253.1 24214772 1151415 complement(2043021..2043968) 1 NC_004342.2 HflC membrane associated protease 2043968 hflC 1151415 hflC Leptospira interrogans serovar Lai str. 56601 HflC membrane associated protease NP_712253.1 2043021 R 189518 CDS NP_712254.2 294828019 1151416 complement(2044000..2044464) 1 NC_004342.2 membrane protease regulatory protein 2044464 1151416 LA_2073 Leptospira interrogans serovar Lai str. 56601 membrane protease regulatory protein NP_712254.2 2044000 R 189518 CDS NP_712256.1 24214775 1151418 2044574..2045017 1 NC_004342.2 hypothetical protein 2045017 1151418 LA_2074 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712256.1 2044574 D 189518 CDS NP_712257.1 24214776 1151419 2045044..2046456 1 NC_004342.2 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 2046456 argH 1151419 argH Leptospira interrogans serovar Lai str. 56601 argininosuccinate lyase NP_712257.1 2045044 D 189518 CDS NP_712258.1 24214777 1151420 2046453..2047328 1 NC_004342.2 peptidyl-prolyl cis-trans isomerase 2047328 1151420 LA_2077 Leptospira interrogans serovar Lai str. 56601 peptidyl-prolyl cis-trans isomerase NP_712258.1 2046453 D 189518 CDS NP_712259.1 24214778 1151421 2047325..2047948 1 NC_004342.2 hypothetical protein 2047948 1151421 LA_2078 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712259.1 2047325 D 189518 CDS NP_712261.2 294828020 1151423 2048520..2049497 1 NC_004342.2 hypothetical protein 2049497 1151423 LA_2080 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712261.2 2048520 D 189518 CDS NP_712262.1 24214781 1151424 2049494..2050519 1 NC_004342.2 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2050519 fliM 1151424 fliM Leptospira interrogans serovar Lai str. 56601 flagellar motor switch protein FliM NP_712262.1 2049494 D 189518 CDS YP_003573320.1 294828021 9006918 complement(2050991..2051212) 1 NC_004342.2 ferredoxin family protein 2051212 fer 9006918 fer Leptospira interrogans serovar Lai str. 56601 ferredoxin family protein YP_003573320.1 2050991 R 189518 CDS NP_712264.2 294828022 1151426 2051438..2052367 1 NC_004342.2 hypothetical protein 2052367 1151426 LA_2083 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712264.2 2051438 D 189518 CDS NP_712265.1 24214784 1151427 complement(2052746..2053036) 1 NC_004342.2 hypothetical protein 2053036 1151427 LA_2084 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712265.1 2052746 R 189518 CDS NP_712268.2 161484952 1151430 2053547..2055358 1 NC_004342.2 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2055358 guaA 1151430 guaA Leptospira interrogans serovar Lai str. 56601 GMP synthase NP_712268.2 2053547 D 189518 CDS NP_712269.2 294828024 1151431 complement(2056270..2056713) 1 NC_004342.2 hypothetical protein 2056713 1151431 LA_2088 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712269.2 2056270 R 189518 CDS NP_712270.1 24214789 1151432 complement(2057647..2060058) 1 NC_004342.2 O-antigen ligase/O-antigen polymerase 2060058 1151432 LA_2089 Leptospira interrogans serovar Lai str. 56601 O-antigen ligase/O-antigen polymerase NP_712270.1 2057647 R 189518 CDS NP_712271.1 24214790 1151433 2060167..2061039 1 NC_004342.2 glycosyltransferase 2061039 1151433 LA_2090 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_712271.1 2060167 D 189518 CDS NP_712272.1 24214791 1151434 2061026..2061802 1 NC_004342.2 hypothetical protein 2061802 1151434 LA_2091 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712272.1 2061026 D 189518 CDS NP_712273.2 294828025 1151435 2061804..2062391 1 NC_004342.2 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 2062391 gmhA 1151435 gmhA Leptospira interrogans serovar Lai str. 56601 phosphoheptose isomerase NP_712273.2 2061804 D 189518 CDS NP_712274.1 24214793 1151436 2062402..2063163 1 NC_004342.2 ABC transporter ATP-binding protein 2063163 dppD 1151436 dppD Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_712274.1 2062402 D 189518 CDS NP_712275.2 294828026 1151437 2063187..2064623 1 NC_004342.2 FHA domain-containing protein 2064623 1151437 LA_2094 Leptospira interrogans serovar Lai str. 56601 FHA domain-containing protein NP_712275.2 2063187 D 189518 CDS NP_712276.1 24214795 1151438 2064781..2066178 1 NC_004342.2 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 2066178 leuC 1151438 leuC Leptospira interrogans serovar Lai str. 56601 isopropylmalate isomerase large subunit NP_712276.1 2064781 D 189518 CDS NP_712277.1 24214796 1151439 2066198..2066818 1 NC_004342.2 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 2066818 leuD 1151439 leuD Leptospira interrogans serovar Lai str. 56601 isopropylmalate isomerase small subunit NP_712277.1 2066198 D 189518 CDS NP_712278.1 24214797 1151440 2066834..2067835 1 NC_004342.2 cysteine synthase 2067835 cysK 1151440 cysK Leptospira interrogans serovar Lai str. 56601 cysteine synthase NP_712278.1 2066834 D 189518 CDS NP_712279.1 24214798 1151441 2067832..2069736 1 NC_004342.2 DNA and RNA helicase 2069736 1151441 LA_2098 Leptospira interrogans serovar Lai str. 56601 DNA and RNA helicase NP_712279.1 2067832 D 189518 CDS NP_712281.2 294828027 1151443 complement(2070555..2070947) 1 NC_004342.2 hypothetical protein 2070947 1151443 LA_2100 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712281.2 2070555 R 189518 CDS YP_003573321.1 294828028 9006921 2071099..2071290 1 NC_004342.2 hypothetical protein 2071290 9006921 LA_2100a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573321.1 2071099 D 189518 CDS NP_712282.1 24214801 1151444 2071344..2071898 1 NC_004342.2 RNA polymerase ECF-type sigma factor 2071898 rpoE 1151444 rpoE Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_712282.1 2071344 D 189518 CDS NP_712283.1 24214802 1151445 2071932..2073152 1 NC_004342.2 hypothetical protein 2073152 1151445 LA_2102 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712283.1 2071932 D 189518 CDS NP_712284.1 24214803 1151446 2073149..2073484 1 NC_004342.2 ATP-dependent Clp protease adaptor protein ClpS 2073484 clpS 1151446 clpS Leptospira interrogans serovar Lai str. 56601 ATP-dependent Clp protease adaptor protein ClpS NP_712284.1 2073149 D 189518 CDS NP_712285.2 294828029 1151447 2073445..2075721 1 NC_004342.2 ATP-dependent protease ClpP 2075721 clpA 1151447 clpA Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease ClpP NP_712285.2 2073445 D 189518 CDS NP_712286.1 24214805 1151448 2075735..2077468 1 NC_004342.2 gamma-glutamyltranspeptidase 2077468 ggt 1151448 ggt Leptospira interrogans serovar Lai str. 56601 gamma-glutamyltranspeptidase NP_712286.1 2075735 D 189518 CDS NP_712287.2 294828030 1151449 2077465..2079027 1 NC_004342.2 gamma-glutamylcysteine synthetase 2079027 gshA 1151449 gshA Leptospira interrogans serovar Lai str. 56601 gamma-glutamylcysteine synthetase NP_712287.2 2077465 D 189518 CDS NP_712288.1 24214807 1151450 2079015..2080046 1 NC_004342.2 ATP-grasp enzyme 2080046 1151450 LA_2107 Leptospira interrogans serovar Lai str. 56601 ATP-grasp enzyme NP_712288.1 2079015 D 189518 CDS NP_712289.1 24214808 1151451 complement(2080043..2080285) 1 NC_004342.2 glutathione S-transferase 2080285 1151451 LA_2108 Leptospira interrogans serovar Lai str. 56601 glutathione S-transferase NP_712289.1 2080043 R 189518 CDS NP_712290.1 24214809 1151452 complement(2080282..2080605) 1 NC_004342.2 glutaredoxin-like protein 2080605 1151452 LA_2109 Leptospira interrogans serovar Lai str. 56601 glutaredoxin-like protein NP_712290.1 2080282 R 189518 CDS NP_712291.2 294828031 1151453 complement(2080602..2080829) 1 NC_004342.2 BolA family protein 2080829 bolA 1151453 bolA Leptospira interrogans serovar Lai str. 56601 BolA family protein NP_712291.2 2080602 R 189518 CDS NP_712293.1 24214812 1151455 complement(2082738..2083001) 1 NC_004342.2 BolA family protein 2083001 bolA 1151455 bolA Leptospira interrogans serovar Lai str. 56601 BolA family protein NP_712293.1 2082738 R 189518 CDS NP_712294.1 24214813 1151456 complement(2083005..2083778) 1 NC_004342.2 ABC transporter membrane protein 2083778 1151456 LA_2113 Leptospira interrogans serovar Lai str. 56601 ABC transporter membrane protein NP_712294.1 2083005 R 189518 CDS NP_712295.1 24214814 1151457 complement(2083775..2084692) 1 NC_004342.2 ABC transporter ATP-binding protein 2084692 ccmA 1151457 ccmA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_712295.1 2083775 R 189518 CDS NP_712296.1 24214815 1151458 complement(2084711..2086093) 1 NC_004342.2 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 2086093 lpd 1151458 lpd Leptospira interrogans serovar Lai str. 56601 dihydrolipoamide dehydrogenase NP_712296.1 2084711 R 189518 CDS NP_712297.1 24214816 1151459 complement(2086217..2086825) 1 NC_004342.2 Zn-dependent hydrolase 2086825 gloB 1151459 gloB Leptospira interrogans serovar Lai str. 56601 Zn-dependent hydrolase NP_712297.1 2086217 R 189518 CDS NP_712298.1 24214817 1151460 complement(2087035..2087349) 1 NC_004342.2 anti-sigma factor antagonist 2087349 1151460 LA_2117 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_712298.1 2087035 R 189518 CDS NP_712299.1 24214818 1151461 2087543..2088499 1 NC_004342.2 metal-dependent hydrolase 2088499 1151461 LA_2118 Leptospira interrogans serovar Lai str. 56601 metal-dependent hydrolase NP_712299.1 2087543 D 189518 CDS NP_712300.1 24214819 1151462 2088569..2090059 1 NC_004342.2 glycerol kinase 2090059 glpK 1151462 glpK Leptospira interrogans serovar Lai str. 56601 glycerol kinase NP_712300.1 2088569 D 189518 CDS NP_712301.1 24214820 1151463 complement(2090053..2091348) 1 NC_004342.2 hypothetical protein 2091348 1151463 LA_2120 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712301.1 2090053 R 189518 CDS NP_712302.1 24214821 1151464 complement(2091482..2091781) 1 NC_004342.2 hypothetical protein 2091781 1151464 LA_2121 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712302.1 2091482 R 189518 CDS NP_712303.1 24214822 1151465 complement(2091778..2092758) 1 NC_004342.2 sigma factor regulatory protein 2092758 1151465 LA_2122 Leptospira interrogans serovar Lai str. 56601 sigma factor regulatory protein NP_712303.1 2091778 R 189518 CDS NP_712304.2 294828032 1151466 complement(2092755..2093369) 1 NC_004342.2 hypothetical protein 2093369 1151466 LA_2123 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712304.2 2092755 R 189518 CDS NP_712305.1 24214824 1151467 complement(2093566..2094987) 1 NC_004342.2 MBOAT family D-alaninealginate export/acetyltransferase membrane protein 2094987 dltB 1151467 dltB Leptospira interrogans serovar Lai str. 56601 MBOAT family D-alaninealginate export/acetyltransferase membrane protein NP_712305.1 2093566 R 189518 CDS NP_712306.1 24214825 1151468 complement(2095023..2096009) 1 NC_004342.2 periplasmic serine protease 2096009 sppA 1151468 sppA Leptospira interrogans serovar Lai str. 56601 periplasmic serine protease NP_712306.1 2095023 R 189518 CDS NP_712308.1 24214827 1151470 2096151..2097056 1 NC_004342.2 hypothetical protein 2097056 1151470 LA_2127 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712308.1 2096151 D 189518 CDS NP_712310.1 24214829 1151472 2098062..2099771 1 NC_004342.2 DNA or RNA helicase 2099771 ssl2 1151472 ssl2 Leptospira interrogans serovar Lai str. 56601 DNA or RNA helicase NP_712310.1 2098062 D 189518 CDS NP_712311.1 24214830 1151473 2099823..2101037 1 NC_004342.2 aspartate aminotransferase 2101037 1151473 LA_2130 Leptospira interrogans serovar Lai str. 56601 aspartate aminotransferase NP_712311.1 2099823 D 189518 CDS NP_712312.1 24214831 1151474 2101041..2101967 1 NC_004342.2 hypothetical protein 2101967 1151474 LA_2131 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712312.1 2101041 D 189518 CDS NP_712313.1 24214832 1151475 2101955..2102788 1 NC_004342.2 hydrolase 2102788 1151475 LA_2132 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_712313.1 2101955 D 189518 CDS NP_712314.2 294828033 1151476 complement(2102745..2104295) 1 NC_004342.2 sodium:solute symporter 2104295 putP 1151476 putP Leptospira interrogans serovar Lai str. 56601 sodium:solute symporter NP_712314.2 2102745 R 189518 CDS NP_712315.1 24214834 1151477 2104508..2105470 1 NC_004342.2 homoserine kinase 2105470 thrB 1151477 thrB Leptospira interrogans serovar Lai str. 56601 homoserine kinase NP_712315.1 2104508 D 189518 CDS NP_712317.1 24214836 1151479 complement(2105947..2106588) 1 NC_004342.2 hypothetical protein 2106588 1151479 LA_2136 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712317.1 2105947 R 189518 CDS NP_712318.1 24214837 1151480 complement(2106597..2106902) 1 NC_004342.2 hypothetical protein 2106902 1151480 LA_2137 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712318.1 2106597 R 189518 CDS NP_712319.1 24214838 1151481 2107161..2108207 1 NC_004342.2 oxidoreductase 2108207 dsbG 1151481 dsbG Leptospira interrogans serovar Lai str. 56601 oxidoreductase NP_712319.1 2107161 D 189518 CDS NP_712320.1 24214839 1151482 2108234..2109214 1 NC_004342.2 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 2109214 mdh 1151482 mdh Leptospira interrogans serovar Lai str. 56601 malate dehydrogenase NP_712320.1 2108234 D 189518 CDS NP_712321.1 24214840 1151483 2109232..2110362 1 NC_004342.2 8-amino-7-oxononanoate synthase 2110362 bioF 1151483 bioF Leptospira interrogans serovar Lai str. 56601 8-amino-7-oxononanoate synthase NP_712321.1 2109232 D 189518 CDS NP_712322.1 24214841 1151484 2110362..2111027 1 NC_004342.2 dethiobiotin synthetase 2111027 bioD 1151484 bioD Leptospira interrogans serovar Lai str. 56601 dethiobiotin synthetase NP_712322.1 2110362 D 189518 CDS NP_712323.1 24214842 1151485 2111024..2112325 1 NC_004342.2 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2112325 bioA 1151485 bioA Leptospira interrogans serovar Lai str. 56601 adenosylmethionine-8-amino-7-oxononanoate aminotransferase NP_712323.1 2111024 D 189518 CDS NP_712324.2 294828034 1151486 2112366..2113421 1 NC_004342.2 biotin synthase 2113421 bioB 1151486 bioB Leptospira interrogans serovar Lai str. 56601 biotin synthase NP_712324.2 2112366 D 189518 CDS NP_712325.2 294828035 1151487 2113978..2114724 1 NC_004342.2 SGNH-hydrolase 2114724 1151487 LA_2144 Leptospira interrogans serovar Lai str. 56601 SGNH-hydrolase NP_712325.2 2113978 D 189518 CDS NP_712326.1 24214845 1151488 2114732..2115613 1 NC_004342.2 phosphoserine phosphatase 2115613 serB 1151488 serB Leptospira interrogans serovar Lai str. 56601 phosphoserine phosphatase NP_712326.1 2114732 D 189518 CDS NP_712327.1 24214846 1151489 complement(2115596..2118142) 1 NC_004342.2 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2118142 mutS 1151489 mutS Leptospira interrogans serovar Lai str. 56601 DNA mismatch repair protein MutS NP_712327.1 2115596 R 189518 CDS NP_712328.1 24214847 1151490 complement(2118139..2118795) 1 NC_004342.2 N-(5'-phosphoribosyl)anthranilate isomerase 2118795 trpF 1151490 trpF Leptospira interrogans serovar Lai str. 56601 N-(5'-phosphoribosyl)anthranilate isomerase NP_712328.1 2118139 R 189518 CDS NP_712330.2 294828036 1151492 2119241..2119738 1 NC_004342.2 hypothetical protein 2119738 1151492 LA_2149 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712330.2 2119241 D 189518 CDS NP_712331.1 24214850 1151493 2119735..2120280 1 NC_004342.2 hypothetical protein 2120280 1151493 LA_2150 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712331.1 2119735 D 189518 CDS NP_712332.1 24214851 1151494 complement(2120277..2120684) 1 NC_004342.2 two-component system signal receiver 2120684 1151494 LA_2151 Leptospira interrogans serovar Lai str. 56601 two-component system signal receiver NP_712332.1 2120277 R 189518 CDS NP_712333.1 24214852 1151495 complement(2120701..2121777) 1 NC_004342.2 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 2121777 leuB 1151495 leuB Leptospira interrogans serovar Lai str. 56601 3-isopropylmalate dehydrogenase NP_712333.1 2120701 R 189518 CDS NP_712334.1 24214853 1151496 complement(2121794..2123014) 1 NC_004342.2 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 2123014 argD 1151496 argD Leptospira interrogans serovar Lai str. 56601 acetylornithine aminotransferase NP_712334.1 2121794 R 189518 CDS NP_712335.1 24214854 1151497 complement(2123011..2124774) 1 NC_004342.2 phosphomannomutase 2124774 manB 1151497 manB Leptospira interrogans serovar Lai str. 56601 phosphomannomutase NP_712335.1 2123011 R 189518 CDS YP_003573322.1 294828037 9006922 complement(2124897..2125016) 1 NC_004342.2 hypothetical protein 2125016 9006922 LA_2154a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573322.1 2124897 R 189518 CDS NP_712336.2 294828038 1151498 2125018..2125242 1 NC_004342.2 hypothetical protein 2125242 1151498 LA_2155 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712336.2 2125018 D 189518 CDS NP_712337.1 24214856 1151499 2125242..2126348 1 NC_004342.2 aspartate aminotransferase 2126348 1151499 LA_2156 Leptospira interrogans serovar Lai str. 56601 aspartate aminotransferase NP_712337.1 2125242 D 189518 CDS NP_712338.2 294828039 1151500 complement(2126475..2126876) 1 NC_004342.2 hypothetical protein 2126876 1151500 LA_2157 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712338.2 2126475 R 189518 CDS NP_712341.2 294828040 1151503 complement(2128345..2129388) 1 NC_004342.2 hypothetical protein 2129388 1151503 LA_2160 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712341.2 2128345 R 189518 CDS NP_712343.1 24214862 1151505 2129534..2129818 1 NC_004342.2 required for 70S ribosome assembly; 50S ribosomal protein L28 2129818 rpmB 1151505 rpmB Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L28 NP_712343.1 2129534 D 189518 CDS NP_712344.2 294828041 1151506 2129745..2130464 1 NC_004342.2 endonuclease III 2130464 nth 1151506 nth Leptospira interrogans serovar Lai str. 56601 endonuclease III NP_712344.2 2129745 D 189518 CDS NP_712345.1 24214864 1151507 2130471..2130893 1 NC_004342.2 acyl-CoA hydrolase 2130893 1151507 LA_2164 Leptospira interrogans serovar Lai str. 56601 acyl-CoA hydrolase NP_712345.1 2130471 D 189518 CDS NP_712346.1 24214865 1151508 2130900..2131367 1 NC_004342.2 peptidyl-tRNA hydrolase 2131367 prfB 1151508 prfB Leptospira interrogans serovar Lai str. 56601 peptidyl-tRNA hydrolase NP_712346.1 2130900 D 189518 CDS NP_712347.1 24214866 1151509 2131893..2133722 1 NC_004342.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2133722 uvrC 1151509 uvrC Leptospira interrogans serovar Lai str. 56601 excinuclease ABC subunit C NP_712347.1 2131893 D 189518 CDS NP_712348.2 294828042 1151510 2133784..2136798 1 NC_004342.2 hypothetical protein 2136798 1151510 LA_2167 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712348.2 2133784 D 189518 CDS NP_712349.2 294828043 1151511 2136795..2138195 1 NC_004342.2 hypothetical protein 2138195 1151511 LA_2168 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712349.2 2136795 D 189518 CDS NP_712350.1 24214869 1151512 2138192..2138368 1 NC_004342.2 lipoprotein 2138368 1151512 LA_2169 Leptospira interrogans serovar Lai str. 56601 lipoprotein NP_712350.1 2138192 D 189518 CDS NP_712351.2 294828044 1151513 2138331..2139974 1 NC_004342.2 lipoprotein with phospholipase D domain 2139974 1151513 LA_2170 Leptospira interrogans serovar Lai str. 56601 lipoprotein with phospholipase D domain NP_712351.2 2138331 D 189518 CDS NP_712352.2 294828045 1151514 complement(2140114..2141433) 1 NC_004342.2 exopolysaccharide production protein 2141433 1151514 LA_2171 Leptospira interrogans serovar Lai str. 56601 exopolysaccharide production protein NP_712352.2 2140114 R 189518 CDS NP_712353.1 24214872 1151515 2141553..2142863 1 NC_004342.2 glycosyltransferase 2142863 1151515 LA_2172 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_712353.1 2141553 D 189518 CDS NP_712354.1 24214873 1151516 complement(2143300..2144361) 1 NC_004342.2 lipopolysaccharide core biosynthesis protein 2144361 1151516 LA_2173 Leptospira interrogans serovar Lai str. 56601 lipopolysaccharide core biosynthesis protein NP_712354.1 2143300 R 189518 CDS NP_712355.2 294828046 1151517 complement(2144358..2144954) 1 NC_004342.2 hypothetical protein 2144954 1151517 LA_2174 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712355.2 2144358 R 189518 CDS NP_712356.2 294828047 1151518 2145082..2146854 1 NC_004342.2 alpha-beta hydrolase family esterase 2146854 rssA 1151518 rssA Leptospira interrogans serovar Lai str. 56601 alpha-beta hydrolase family esterase NP_712356.2 2145082 D 189518 CDS NP_712357.2 294828048 1151519 complement(2146837..2147481) 1 NC_004342.2 hypothetical protein 2147481 1151519 LA_2176 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712357.2 2146837 R 189518 CDS NP_712358.1 24214877 1151520 complement(2147471..2149408) 1 NC_004342.2 long-chain-fatty-acid CoA ligase 2149408 faa1 1151520 faa1 Leptospira interrogans serovar Lai str. 56601 long-chain-fatty-acid CoA ligase NP_712358.1 2147471 R 189518 CDS NP_712359.1 24214878 1151521 complement(2149414..2150430) 1 NC_004342.2 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 2150430 argC 1151521 argC Leptospira interrogans serovar Lai str. 56601 N-acetyl-gamma-glutamyl-phosphate reductase NP_712359.1 2149414 R 189518 CDS NP_712360.1 24214879 1151522 complement(2150681..2151781) 1 NC_004342.2 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2151781 recA 1151522 recA Leptospira interrogans serovar Lai str. 56601 recombinase A NP_712360.1 2150681 R 189518 CDS NP_712361.1 24214880 1151523 complement(2152003..2152806) 1 NC_004342.2 hypothetical protein 2152806 1151523 LA_2180 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712361.1 2152003 R 189518 CDS NP_712363.2 294828049 1151525 2153972..2154361 1 NC_004342.2 HIT family hydrolase 2154361 1151525 LA_2182 Leptospira interrogans serovar Lai str. 56601 HIT family hydrolase NP_712363.2 2153972 D 189518 CDS NP_712364.1 24214883 1151526 2154399..2154776 1 NC_004342.2 hypothetical protein 2154776 1151526 LA_2183 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712364.1 2154399 D 189518 CDS NP_712365.1 24214884 1151527 2154825..2156210 1 NC_004342.2 Zn-dependent protease 2156210 tldD 1151527 tldD Leptospira interrogans serovar Lai str. 56601 Zn-dependent protease NP_712365.1 2154825 D 189518 CDS NP_712366.2 294828050 1151528 2156207..2157541 1 NC_004342.2 Zn-dependent protease 2157541 tldD 1151528 tldD Leptospira interrogans serovar Lai str. 56601 Zn-dependent protease NP_712366.2 2156207 D 189518 CDS NP_712367.1 24214886 1151529 2157615..2163419 1 NC_004342.2 hypothetical protein 2163419 1151529 LA_2186 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712367.1 2157615 D 189518 CDS NP_712368.2 294828051 1151530 2163624..2165711 1 NC_004342.2 penicillin binding protein 2165711 pbpC 1151530 pbpC Leptospira interrogans serovar Lai str. 56601 penicillin binding protein NP_712368.2 2163624 D 189518 CDS NP_712369.1 24214888 1151531 2165764..2166561 1 NC_004342.2 ATPase 2166561 1151531 LA_2188 Leptospira interrogans serovar Lai str. 56601 ATPase NP_712369.1 2165764 D 189518 CDS NP_712370.1 24214889 1151532 2166563..2167750 1 NC_004342.2 hypothetical protein 2167750 1151532 LA_2189 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712370.1 2166563 D 189518 CDS NP_712371.1 24214890 1151533 complement(2168129..2169043) 1 NC_004342.2 2-dehydropantoate 2-reductase 2169043 apbA 1151533 apbA Leptospira interrogans serovar Lai str. 56601 2-dehydropantoate 2-reductase NP_712371.1 2168129 R 189518 CDS NP_712372.1 24214891 1151534 complement(2169045..2169242) 1 NC_004342.2 hypothetical protein 2169242 1151534 LA_2191 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712372.1 2169045 R 189518 CDS NP_712373.2 294828052 1151535 complement(2169292..2170041) 1 NC_004342.2 hypothetical protein 2170041 1151535 LA_2192 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712373.2 2169292 R 189518 CDS NP_712374.1 24214893 1151536 complement(2170049..2172067) 1 NC_004342.2 DNA helicase UvrD 2172067 uvrD 1151536 uvrD Leptospira interrogans serovar Lai str. 56601 DNA helicase UvrD NP_712374.1 2170049 R 189518 CDS NP_712375.2 294828053 1151537 complement(2172048..2172518) 1 NC_004342.2 peptidyl-prolyl cis-trans isomerase 2172518 slpA 1151537 slpA Leptospira interrogans serovar Lai str. 56601 peptidyl-prolyl cis-trans isomerase NP_712375.2 2172048 R 189518 CDS NP_712376.1 24214895 1151538 complement(2172602..2172955) 1 NC_004342.2 hypothetical protein 2172955 1151538 LA_2195 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712376.1 2172602 R 189518 CDS NP_712377.1 24214896 1151539 complement(2173214..2175583) 1 NC_004342.2 hypothetical protein 2175583 1151539 LA_2196 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712377.1 2173214 R 189518 CDS NP_712378.1 24214897 1151540 complement(2176496..2178505) 1 NC_004342.2 2,4-dienoyl-CoA reductase 2178505 nemA 1151540 nemA Leptospira interrogans serovar Lai str. 56601 2,4-dienoyl-CoA reductase NP_712378.1 2176496 R 189518 CDS NP_712381.1 24214900 1151543 2179273..2179833 1 NC_004342.2 amidase 2179833 1151543 LA_2200 Leptospira interrogans serovar Lai str. 56601 amidase NP_712381.1 2179273 D 189518 CDS NP_712383.1 24214902 1151545 complement(2180227..2181813) 1 NC_004342.2 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 2181813 leuA 1151545 leuA Leptospira interrogans serovar Lai str. 56601 2-isopropylmalate synthase NP_712383.1 2180227 R 189518 CDS NP_712384.1 24214903 1151546 2181882..2182214 1 NC_004342.2 hypothetical protein 2182214 1151546 LA_2203 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712384.1 2181882 D 189518 CDS NP_712385.2 294828054 1151547 complement(2182334..2182840) 1 NC_004342.2 hypothetical protein 2182840 1151547 LA_2204 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712385.2 2182334 R 189518 CDS NP_712386.1 24214905 1151548 complement(2183405..2183971) 1 NC_004342.2 hypothetical protein 2183971 1151548 LA_2205 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712386.1 2183405 R 189518 CDS NP_712387.1 24214906 1151549 complement(2183984..2184502) 1 NC_004342.2 hypothetical protein 2184502 1151549 LA_2206 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712387.1 2183984 R 189518 CDS NP_712388.2 294828055 1151550 complement(2184661..2185368) 1 NC_004342.2 hypothetical protein 2185368 1151550 LA_2207 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712388.2 2184661 R 189518 CDS NP_712389.1 24214908 1151551 2185532..2187139 1 NC_004342.2 hypothetical protein 2187139 1151551 LA_2208 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712389.1 2185532 D 189518 CDS NP_712390.1 24214909 1151552 2187120..2188067 1 NC_004342.2 translation factor Sua5 2188067 sua5 1151552 sua5 Leptospira interrogans serovar Lai str. 56601 translation factor Sua5 NP_712390.1 2187120 D 189518 CDS NP_712392.1 24214911 1151554 complement(2189706..2191445) 1 NC_004342.2 periplasmic serine protease 2191445 sppA 1151554 sppA Leptospira interrogans serovar Lai str. 56601 periplasmic serine protease NP_712392.1 2189706 R 189518 CDS NP_712393.1 24214912 1151555 2191555..2194401 1 NC_004342.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 2194401 uvrA 1151555 uvrA Leptospira interrogans serovar Lai str. 56601 excinuclease ABC subunit A NP_712393.1 2191555 D 189518 CDS NP_712394.2 294828056 1151556 2194418..2195467 1 NC_004342.2 hypothetical protein 2195467 1151556 LA_2213 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712394.2 2194418 D 189518 CDS NP_712395.2 294828057 1151557 complement(2195626..2196576) 1 NC_004342.2 Co/Zn/Cd efflux pump 2196576 czcD 1151557 czcD Leptospira interrogans serovar Lai str. 56601 Co/Zn/Cd efflux pump NP_712395.2 2195626 R 189518 CDS NP_712396.2 294828058 1151558 complement(2196576..2197586) 1 NC_004342.2 endoflagellar motor protein B 2197586 motB 1151558 motB Leptospira interrogans serovar Lai str. 56601 endoflagellar motor protein B NP_712396.2 2196576 R 189518 CDS NP_712398.2 294828059 1151560 2197726..2199117 1 NC_004342.2 magnesium transporter 2199117 mgtE 1151560 mgtE Leptospira interrogans serovar Lai str. 56601 magnesium transporter NP_712398.2 2197726 D 189518 CDS NP_712400.1 24214919 1151562 2199326..2199976 1 NC_004342.2 hypothetical protein 2199976 1151562 LA_2219 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712400.1 2199326 D 189518 CDS NP_712401.1 24214920 1151563 2200477..2201196 1 NC_004342.2 magnesium transport P-type atpase 2201196 1151563 LA_2220 Leptospira interrogans serovar Lai str. 56601 magnesium transport P-type atpase NP_712401.1 2200477 D 189518 CDS NP_712402.1 24214921 1151564 2201180..2202988 1 NC_004342.2 magnesium transport P-type atpase 2202988 mgtA 1151564 mgtA Leptospira interrogans serovar Lai str. 56601 magnesium transport P-type atpase NP_712402.1 2201180 D 189518 CDS NP_712403.1 24214922 1151565 2203633..2206131 1 NC_004342.2 two component system sensor histidine kinase\response regulator 2206131 1151565 LA_2222 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase\response regulator NP_712403.1 2203633 D 189518 CDS NP_712404.1 24214923 1151566 2206170..2207318 1 NC_004342.2 two component system sensor histidine kinase 2207318 1151566 LA_2223 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase NP_712404.1 2206170 D 189518 CDS NP_712407.1 24214926 1151569 complement(2208103..2209227) 1 NC_004342.2 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 2209227 fbp 1151569 fbp Leptospira interrogans serovar Lai str. 56601 fructose-1,6-bisphosphatase NP_712407.1 2208103 R 189518 CDS NP_712408.1 24214927 1151570 2209295..2209738 1 NC_004342.2 hypothetical protein 2209738 1151570 LA_2227 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712408.1 2209295 D 189518 CDS YP_003573323.1 294828060 9006923 2209702..2209896 1 NC_004342.2 hypothetical protein 2209896 9006923 LA_2227a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573323.1 2209702 D 189518 CDS NP_712409.2 294828061 1151571 2209850..2210062 1 NC_004342.2 hypothetical protein 2210062 1151571 LA_2228 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712409.2 2209850 D 189518 CDS NP_712410.2 161484951 1151572 2210238..2210447 1 NC_004342.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 2210447 rpsU 1151572 rpsU Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S21 NP_712410.2 2210238 D 189518 CDS NP_712411.1 24214930 1151573 2210507..2210953 1 NC_004342.2 hypothetical protein 2210953 1151573 LA_2230 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712411.1 2210507 D 189518 CDS NP_712412.1 24214931 1151574 2210972..2212768 1 NC_004342.2 DNA primase 2212768 dnaG 1151574 dnaG Leptospira interrogans serovar Lai str. 56601 DNA primase NP_712412.1 2210972 D 189518 CDS NP_712413.1 24214932 1151575 2212785..2214542 1 NC_004342.2 RNA polymerase sigma-70 factor 2214542 rpoD 1151575 rpoD Leptospira interrogans serovar Lai str. 56601 RNA polymerase sigma-70 factor NP_712413.1 2212785 D 189518 CDS NP_712417.1 24214936 1151579 complement(2215173..2216825) 1 NC_004342.2 glycerol-3-phosphate dehydrogenase 2216825 glpA 1151579 glpA Leptospira interrogans serovar Lai str. 56601 glycerol-3-phosphate dehydrogenase NP_712417.1 2215173 R 189518 CDS NP_712418.1 24214937 1151580 2216858..2218075 1 NC_004342.2 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2218075 tyrS 1151580 tyrS Leptospira interrogans serovar Lai str. 56601 tyrosyl-tRNA synthetase NP_712418.1 2216858 D 189518 CDS NP_712419.1 24214938 1151581 2218121..2219317 1 NC_004342.2 polysaccharide deacetylase 2219317 1151581 LA_2238 Leptospira interrogans serovar Lai str. 56601 polysaccharide deacetylase NP_712419.1 2218121 D 189518 CDS NP_712421.2 294828062 1151583 complement(2219721..2220287) 1 NC_004342.2 hypothetical protein 2220287 1151583 LA_2240 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712421.2 2219721 R 189518 CDS NP_712422.1 24214941 1151584 complement(2220737..2221297) 1 NC_004342.2 hypothetical protein 2221297 1151584 LA_2241 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712422.1 2220737 R 189518 CDS NP_712423.1 24214942 1151585 complement(2221324..2223732) 1 NC_004342.2 TonB-dependent outer membrane receptor 2223732 1151585 LA_2242 Leptospira interrogans serovar Lai str. 56601 TonB-dependent outer membrane receptor NP_712423.1 2221324 R 189518 CDS NP_712425.1 24214944 1151587 complement(2224952..2225452) 1 NC_004342.2 hypothetical protein 2225452 1151587 LA_2244 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712425.1 2224952 R 189518 CDS NP_712427.2 294828063 1151589 2226347..2227993 1 NC_004342.2 methyl-accepting chemotaxis protein 2227993 1151589 LA_2246 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_712427.2 2226347 D 189518 CDS NP_712429.2 294828064 1151591 2228605..2228889 1 NC_004342.2 hypothetical protein 2228889 1151591 LA_2248 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712429.2 2228605 D 189518 CDS NP_712430.1 24214949 1151592 2229788..2230669 1 NC_004342.2 hypothetical protein 2230669 1151592 LA_2249 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712430.1 2229788 D 189518 CDS NP_712431.2 294828065 1151593 complement(2230983..2231849) 1 NC_004342.2 endonuclease 2231849 1151593 LA_2250 Leptospira interrogans serovar Lai str. 56601 endonuclease NP_712431.2 2230983 R 189518 CDS NP_712432.2 294828066 1151594 complement(2232610..2233728) 1 NC_004342.2 phosphoesterase-like protein 2233728 1151594 LA_2251 Leptospira interrogans serovar Lai str. 56601 phosphoesterase-like protein NP_712432.2 2232610 R 189518 CDS NP_712433.1 24214952 1151595 2233887..2234432 1 NC_004342.2 DJ-1/PfpI family intracellular protease 2234432 thiJ 1151595 thiJ Leptospira interrogans serovar Lai str. 56601 DJ-1/PfpI family intracellular protease NP_712433.1 2233887 D 189518 CDS NP_712434.1 24214953 1151596 2234429..2235169 1 NC_004342.2 transcriptional regulator 2235169 sir2 1151596 sir2 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_712434.1 2234429 D 189518 CDS NP_712435.1 24214954 1151597 2235370..2235606 1 NC_004342.2 hypothetical protein 2235606 1151597 LA_2254 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712435.1 2235370 D 189518 CDS NP_712436.1 24214955 1151598 complement(2236001..2237071) 1 NC_004342.2 hypothetical protein 2237071 1151598 LA_2255 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712436.1 2236001 R 189518 CDS NP_712437.1 24214956 1151599 complement(2237081..2238565) 1 NC_004342.2 MBOAT family D-alaninealginate export/acetyltransferase membrane protein 2238565 dltB 1151599 dltB Leptospira interrogans serovar Lai str. 56601 MBOAT family D-alaninealginate export/acetyltransferase membrane protein NP_712437.1 2237081 R 189518 CDS NP_712438.2 294828067 1151600 complement(2238569..2239072) 1 NC_004342.2 hypothetical protein 2239072 1151600 LA_2258 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712438.2 2238569 R 189518 CDS NP_712439.1 24214958 1151601 2239145..2239972 1 NC_004342.2 hypothetical protein 2239972 1151601 LA_2257 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712439.1 2239145 D 189518 CDS NP_712440.1 24214959 1151602 2240259..2240750 1 NC_004342.2 hypothetical protein 2240750 1151602 LA_2259 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712440.1 2240259 D 189518 CDS NP_712441.2 294828068 1151603 2240839..2241417 1 NC_004342.2 transcriptional regulator 2241417 1151603 LA_2260 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_712441.2 2240839 D 189518 CDS NP_712442.2 294828069 1151604 complement(2241422..2243074) 1 NC_004342.2 glycerol-3-phosphate dehydrogenase 2243074 glpA 1151604 glpA Leptospira interrogans serovar Lai str. 56601 glycerol-3-phosphate dehydrogenase NP_712442.2 2241422 R 189518 CDS NP_712443.1 24214962 1151605 2243254..2244945 1 NC_004342.2 alkylglycerone-phosphate synthase 2244945 1151605 LA_2262 Leptospira interrogans serovar Lai str. 56601 alkylglycerone-phosphate synthase NP_712443.1 2243254 D 189518 CDS NP_712444.1 24214963 1151606 2244942..2245751 1 NC_004342.2 ankyrin repeat-containing protein 2245751 arp 1151606 arp Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_712444.1 2244942 D 189518 CDS NP_712445.1 24214964 1151607 2245835..2246092 1 NC_004342.2 ankyrin repeat-containing protein 2246092 1151607 LA_2264 Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_712445.1 2245835 D 189518 CDS NP_712446.1 24214965 1151608 complement(2246263..2247030) 1 NC_004342.2 enoyl-CoA hydratase 2247030 caiD 1151608 caiD Leptospira interrogans serovar Lai str. 56601 enoyl-CoA hydratase NP_712446.1 2246263 R 189518 CDS NP_712447.1 24214966 1151609 complement(2247222..2248016) 1 NC_004342.2 hypothetical protein 2248016 1151609 LA_2266 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712447.1 2247222 R 189518 CDS NP_712448.1 24214967 1151610 complement(2248023..2250011) 1 NC_004342.2 TPR-repeat-containing protein 2250011 1151610 LA_2267 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_712448.1 2248023 R 189518 CDS NP_712449.1 24214968 1151611 2250145..2251425 1 NC_004342.2 hypothetical protein 2251425 1151611 LA_2268 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712449.1 2250145 D 189518 CDS NP_712450.1 24214969 1151612 2251400..2252524 1 NC_004342.2 cysteine desulfhydrase 2252524 nifS 1151612 nifS Leptospira interrogans serovar Lai str. 56601 cysteine desulfhydrase NP_712450.1 2251400 D 189518 CDS NP_712453.1 24214972 1151615 2253013..2253825 1 NC_004342.2 hypothetical protein 2253825 1151615 LA_2272 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712453.1 2253013 D 189518 CDS NP_712454.2 294828070 1151616 2253950..2254624 1 NC_004342.2 hypothetical protein 2254624 1151616 LA_2273 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712454.2 2253950 D 189518 CDS NP_712455.2 294828071 1151617 complement(2254716..2255840) 1 NC_004342.2 deoxyguanosinetriphosphate triphosphohydrolase 2255840 dgt 1151617 dgt Leptospira interrogans serovar Lai str. 56601 deoxyguanosinetriphosphate triphosphohydrolase NP_712455.2 2254716 R 189518 CDS NP_712456.1 24214975 1151618 2255985..2256590 1 NC_004342.2 DedA-like protein 2256590 1151618 LA_2275 Leptospira interrogans serovar Lai str. 56601 DedA-like protein NP_712456.1 2255985 D 189518 CDS NP_712457.1 24214976 1151619 2256642..2257196 1 NC_004342.2 HNH family endonuclease 2257196 mcrA 1151619 mcrA Leptospira interrogans serovar Lai str. 56601 HNH family endonuclease NP_712457.1 2256642 D 189518 CDS NP_712458.1 24214977 1151620 2257193..2257690 1 NC_004342.2 hypothetical protein 2257690 1151620 LA_2277 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712458.1 2257193 D 189518 CDS NP_712459.2 294828072 1151621 complement(2257677..2258159) 1 NC_004342.2 hypothetical protein 2258159 1151621 LA_2278 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712459.2 2257677 R 189518 CDS NP_712460.2 294828073 1151622 complement(2258153..2258572) 1 NC_004342.2 hypothetical protein 2258572 1151622 LA_2279 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712460.2 2258153 R 189518 CDS NP_712461.1 24214980 1151623 complement(2258578..2259030) 1 NC_004342.2 endoflagellar biosynthesis chaperone 2259030 fliS 1151623 fliS Leptospira interrogans serovar Lai str. 56601 endoflagellar biosynthesis chaperone NP_712461.1 2258578 R 189518 CDS NP_712463.1 24214982 1151625 2259444..2260070 1 NC_004342.2 phosphoribosylglycinamide formyltransferase 2260070 purN 1151625 purN Leptospira interrogans serovar Lai str. 56601 phosphoribosylglycinamide formyltransferase NP_712463.1 2259444 D 189518 CDS NP_712464.1 24214983 1151626 2260074..2261609 1 NC_004342.2 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2261609 purH 1151626 purH Leptospira interrogans serovar Lai str. 56601 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NP_712464.1 2260074 D 189518 CDS NP_712465.1 24214984 1151627 2261612..2262238 1 NC_004342.2 hypothetical protein 2262238 1151627 LA_2284 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712465.1 2261612 D 189518 CDS NP_712466.1 24214985 1151628 2262269..2263000 1 NC_004342.2 hypothetical protein 2263000 1151628 LA_2285 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712466.1 2262269 D 189518 CDS NP_712467.1 24214986 1151629 2263180..2263824 1 NC_004342.2 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 2263824 mipB 1151629 mipB Leptospira interrogans serovar Lai str. 56601 translaldolase NP_712467.1 2263180 D 189518 CDS NP_712468.1 24214987 1151630 2263976..2264284 1 NC_004342.2 hypothetical protein 2264284 1151630 LA_2287 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712468.1 2263976 D 189518 CDS NP_712470.2 294828074 1151632 complement(2265411..2266457) 1 NC_004342.2 hypothetical protein 2266457 1151632 LA_2289 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712470.2 2265411 R 189518 CDS NP_712471.2 294828075 1151633 complement(2266471..2267889) 1 NC_004342.2 MBOAT family D-alaninealginate export/acetyltransferase membrane protein 2267889 dltB 1151633 dltB Leptospira interrogans serovar Lai str. 56601 MBOAT family D-alaninealginate export/acetyltransferase membrane protein NP_712471.2 2266471 R 189518 CDS NP_712472.1 24214991 1151634 complement(2267886..2268626) 1 NC_004342.2 pseudouridylate synthase 2268626 rsuA 1151634 rsuA Leptospira interrogans serovar Lai str. 56601 pseudouridylate synthase NP_712472.1 2267886 R 189518 CDS NP_712473.1 24214992 1151635 2268726..2269631 1 NC_004342.2 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2269631 lipA 1151635 lipA Leptospira interrogans serovar Lai str. 56601 lipoyl synthase NP_712473.1 2268726 D 189518 CDS NP_712474.1 24214993 1151636 2269619..2269918 1 NC_004342.2 hypothetical protein 2269918 1151636 LA_2293 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712474.1 2269619 D 189518 CDS NP_712475.2 294828076 1151637 2270341..2271510 1 NC_004342.2 ISlin1 transposase 2271510 1151637 LA_2294 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_712475.2 2270341 D 189518 CDS NP_712476.2 294828077 1151638 complement(2272543..2273709) 1 NC_004342.2 hypothetical protein 2273709 lipL45 1151638 lipL45 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712476.2 2272543 R 189518 CDS NP_712477.2 294828078 1151639 complement(2273809..2275059) 1 NC_004342.2 glucose/sorbosone dehydrogenase 2275059 1151639 LA_2296 Leptospira interrogans serovar Lai str. 56601 glucose/sorbosone dehydrogenase NP_712477.2 2273809 R 189518 CDS NP_712478.1 24214997 1151640 2275384..2276694 1 NC_004342.2 hypothetical protein 2276694 1151640 LA_2297 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712478.1 2275384 D 189518 CDS NP_712479.2 294828079 1151641 2277564..2278661 1 NC_004342.2 hypothetical protein 2278661 1151641 LA_2298 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712479.2 2277564 D 189518 CDS NP_712480.1 24214999 1151642 2278763..2278957 1 NC_004342.2 hypothetical protein 2278957 1151642 LA_2299 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712480.1 2278763 D 189518 CDS NP_712481.1 24215000 1151643 complement(2278987..2279667) 1 NC_004342.2 hypothetical protein 2279667 1151643 LA_2300 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712481.1 2278987 R 189518 CDS NP_712482.1 24215001 1151644 complement(2279680..2280354) 1 NC_004342.2 hypothetical protein 2280354 1151644 LA_2301 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712482.1 2279680 R 189518 CDS NP_712483.1 24215002 1151645 complement(2280370..2281035) 1 NC_004342.2 hypothetical protein 2281035 1151645 LA_2302 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712483.1 2280370 R 189518 CDS NP_712484.1 24215003 1151646 2281118..2281786 1 NC_004342.2 short chain dehydrogenase 2281786 fabG 1151646 fabG Leptospira interrogans serovar Lai str. 56601 short chain dehydrogenase NP_712484.1 2281118 D 189518 CDS NP_712487.2 294828080 1151649 2282122..2283135 1 NC_004342.2 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2283135 lpxC 1151649 lpxC Leptospira interrogans serovar Lai str. 56601 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NP_712487.2 2282122 D 189518 CDS NP_712488.1 24215007 1151650 2283181..2285013 1 NC_004342.2 phosphoenolpyruvate-protein phosphotransferase 2285013 ptsA 1151650 ptsA Leptospira interrogans serovar Lai str. 56601 phosphoenolpyruvate-protein phosphotransferase NP_712488.1 2283181 D 189518 CDS NP_712489.2 294828081 1151651 complement(2285010..2285690) 1 NC_004342.2 hypothetical protein 2285690 1151651 LA_2308 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712489.2 2285010 R 189518 CDS NP_712490.1 24215009 1151652 complement(2285784..2287829) 1 NC_004342.2 long-chain-fatty-acid CoA ligase 2287829 faa1 1151652 faa1 Leptospira interrogans serovar Lai str. 56601 long-chain-fatty-acid CoA ligase NP_712490.1 2285784 R 189518 CDS NP_712492.1 24215011 1151654 complement(2288246..2288743) 1 NC_004342.2 thioredoxin 2288743 trxA 1151654 trxA Leptospira interrogans serovar Lai str. 56601 thioredoxin NP_712492.1 2288246 R 189518 CDS NP_712493.1 24215012 1151655 2288742..2289266 1 NC_004342.2 hypothetical protein 2289266 1151655 LA_2311 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712493.1 2288742 D 189518 CDS NP_712495.1 24215014 1151657 complement(2290123..2291286) 1 NC_004342.2 mannosyltransferase 2291286 1151657 LA_2314 Leptospira interrogans serovar Lai str. 56601 mannosyltransferase NP_712495.1 2290123 R 189518 CDS NP_712496.1 24215015 1151658 complement(2291391..2292236) 1 NC_004342.2 inositol monophosphatase 2292236 cysQ 1151658 cysQ Leptospira interrogans serovar Lai str. 56601 inositol monophosphatase NP_712496.1 2291391 R 189518 CDS NP_712497.1 24215016 1151659 complement(2292261..2292701) 1 NC_004342.2 hypothetical protein 2292701 1151659 LA_2316 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712497.1 2292261 R 189518 CDS NP_712498.1 24215017 1151660 complement(2292764..2294962) 1 NC_004342.2 DNA helicase UvrD 2294962 uvrD 1151660 uvrD Leptospira interrogans serovar Lai str. 56601 DNA helicase UvrD NP_712498.1 2292764 R 189518 CDS NP_712499.1 24215018 1151661 complement(2294966..2297893) 1 NC_004342.2 hypothetical protein 2297893 1151661 LA_2318 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712499.1 2294966 R 189518 CDS NP_712500.1 24215019 1151662 complement(2297912..2298361) 1 NC_004342.2 ExbD-like biopolymer transport protein 2298361 exbD 1151662 exbD Leptospira interrogans serovar Lai str. 56601 ExbD-like biopolymer transport protein NP_712500.1 2297912 R 189518 CDS NP_712501.1 24215020 1151663 complement(2298364..2298969) 1 NC_004342.2 biopolymer transport protein TolQ 2298969 tolQ 1151663 tolQ Leptospira interrogans serovar Lai str. 56601 biopolymer transport protein TolQ NP_712501.1 2298364 R 189518 CDS NP_712502.1 24215021 1151664 complement(2299081..2300787) 1 NC_004342.2 DNA repair protein RecN 2300787 recN 1151664 recN Leptospira interrogans serovar Lai str. 56601 DNA repair protein RecN NP_712502.1 2299081 R 189518 CDS NP_712503.1 24215022 1151665 complement(2301146..2301343) 1 NC_004342.2 hypothetical protein 2301343 1151665 LA_2322 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712503.1 2301146 R 189518 CDS NP_712504.1 24215023 1151666 2301552..2302256 1 NC_004342.2 hypothetical protein 2302256 1151666 LA_2323 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712504.1 2301552 D 189518 CDS NP_712505.1 24215024 1151667 2302246..2303016 1 NC_004342.2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2303016 fabG 1151667 fabG Leptospira interrogans serovar Lai str. 56601 3-ketoacyl-ACP reductase NP_712505.1 2302246 D 189518 CDS NP_712506.1 24215025 1151668 2303193..2303492 1 NC_004342.2 transcriptional regulator 2303492 arsR 1151668 arsR Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_712506.1 2303193 D 189518 CDS NP_712507.2 294828082 1151669 complement(2303520..2304491) 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 2304491 1151669 LA_2326 Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_712507.2 2303520 R 189518 CDS NP_712508.1 24215027 1151670 complement(2304506..2306263) 1 NC_004342.2 3-polyprenyl-4-hydroxybenzoate decarboxylase 2306263 ubiD 1151670 ubiD Leptospira interrogans serovar Lai str. 56601 3-polyprenyl-4-hydroxybenzoate decarboxylase NP_712508.1 2304506 R 189518 CDS NP_712509.1 24215028 1151671 complement(2306260..2307387) 1 NC_004342.2 A/G-specific adenine glycosylase 2307387 mutY 1151671 mutY Leptospira interrogans serovar Lai str. 56601 A/G-specific adenine glycosylase NP_712509.1 2306260 R 189518 CDS NP_712510.1 24215029 1151672 complement(2307469..2308566) 1 NC_004342.2 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2308566 1151672 LA_2329 Leptospira interrogans serovar Lai str. 56601 GTP-dependent nucleic acid-binding protein EngD NP_712510.1 2307469 R 189518 CDS NP_712511.2 294828083 1151673 complement(2308612..2309865) 1 NC_004342.2 hypothetical protein 2309865 1151673 LA_2330 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712511.2 2308612 R 189518 CDS NP_712512.1 24215031 1151674 complement(2309872..2310519) 1 NC_004342.2 hypothetical protein 2310519 1151674 LA_2331 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712512.1 2309872 R 189518 CDS NP_712513.1 24215032 1151675 2310582..2311526 1 NC_004342.2 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 2311526 ubiA 1151675 ubiA Leptospira interrogans serovar Lai str. 56601 prenyltransferase NP_712513.1 2310582 D 189518 CDS NP_712516.1 24215035 1151678 2312959..2313573 1 NC_004342.2 3-polyprenyl-4-hydroxybenzoate decarboxylase 2313573 ubiX 1151678 ubiX Leptospira interrogans serovar Lai str. 56601 3-polyprenyl-4-hydroxybenzoate decarboxylase NP_712516.1 2312959 D 189518 CDS NP_712517.1 24215036 1151679 complement(2313580..2314269) 1 NC_004342.2 hypothetical protein 2314269 1151679 LA_2336 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712517.1 2313580 R 189518 CDS NP_712518.1 24215037 1151680 complement(2314316..2315359) 1 NC_004342.2 chromosome partitioning ATPase 2315359 mrp 1151680 mrp Leptospira interrogans serovar Lai str. 56601 chromosome partitioning ATPase NP_712518.1 2314316 R 189518 CDS NP_712519.1 24215038 1151681 complement(2315361..2316239) 1 NC_004342.2 phosphohydrolase 2316239 1151681 LA_2338 Leptospira interrogans serovar Lai str. 56601 phosphohydrolase NP_712519.1 2315361 R 189518 CDS NP_712520.1 24215039 1151682 complement(2316236..2316496) 1 NC_004342.2 biotin-requiring enzyme 2316496 1151682 LA_2339 Leptospira interrogans serovar Lai str. 56601 biotin-requiring enzyme NP_712520.1 2316236 R 189518 CDS NP_712521.1 24215040 1151683 2316564..2317394 1 NC_004342.2 hypothetical protein 2317394 1151683 LA_2340 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712521.1 2316564 D 189518 CDS NP_712523.1 24215042 1151685 2317896..2318414 1 NC_004342.2 hypothetical protein 2318414 1151685 LA_2342 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712523.1 2317896 D 189518 CDS NP_712524.2 294828084 1151686 complement(2318634..2320007) 1 NC_004342.2 glucose/sorbosone dehydrogenase 2320007 1151686 LA_2343 Leptospira interrogans serovar Lai str. 56601 glucose/sorbosone dehydrogenase NP_712524.2 2318634 R 189518 CDS NP_712526.1 24215045 1151688 complement(2321434..2322873) 1 NC_004342.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 2322873 hslU 1151688 hslU Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease ATP-binding subunit HslU NP_712526.1 2321434 R 189518 CDS NP_712527.1 24215046 1151689 complement(2322883..2323425) 1 NC_004342.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 2323425 hslV 1151689 hslV Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease peptidase subunit NP_712527.1 2322883 R 189518 CDS NP_712528.2 294828085 1151690 complement(2323412..2324347) 1 NC_004342.2 integrase/recombinase XerD 2324347 xerD 1151690 xerD Leptospira interrogans serovar Lai str. 56601 integrase/recombinase XerD NP_712528.2 2323412 R 189518 CDS NP_712530.1 24215049 1151692 complement(2324567..2325139) 1 NC_004342.2 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2325139 pth 1151692 pth Leptospira interrogans serovar Lai str. 56601 peptidyl-tRNA hydrolase NP_712530.1 2324567 R 189518 CDS NP_712531.1 24215050 1151693 complement(2325127..2326677) 1 NC_004342.2 isopropylmalate/homocitrate/citramalate synthase 2326677 leuA 1151693 leuA Leptospira interrogans serovar Lai str. 56601 isopropylmalate/homocitrate/citramalate synthase NP_712531.1 2325127 R 189518 CDS NP_712532.2 294828086 1151694 complement(2326674..2326985) 1 NC_004342.2 Smr domain-containing protein 2326985 1151694 LA_2351 Leptospira interrogans serovar Lai str. 56601 Smr domain-containing protein NP_712532.2 2326674 R 189518 CDS NP_712533.1 24215052 1151695 2327132..2328691 1 NC_004342.2 hypothetical protein 2328691 1151695 LA_2352 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712533.1 2327132 D 189518 CDS NP_712534.1 24215053 1151696 complement(2329690..2330331) 1 NC_004342.2 hypothetical protein 2330331 1151696 LA_2354 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712534.1 2329690 R 189518 CDS NP_712535.2 294828087 1151697 2330356..2330928 1 NC_004342.2 hypothetical protein 2330928 1151697 LA_2353 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712535.2 2330356 D 189518 CDS NP_712536.1 24215055 1151698 2330935..2332065 1 NC_004342.2 permease 2332065 1151698 LA_2355 Leptospira interrogans serovar Lai str. 56601 permease NP_712536.1 2330935 D 189518 CDS NP_712537.1 24215056 1151699 2332069..2333337 1 NC_004342.2 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2333337 xseA 1151699 xseA Leptospira interrogans serovar Lai str. 56601 exodeoxyribonuclease VII large subunit NP_712537.1 2332069 D 189518 CDS NP_712538.1 24215057 1151700 2333339..2333626 1 NC_004342.2 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2333626 xseB 1151700 xseB Leptospira interrogans serovar Lai str. 56601 exodeoxyribonuclease VII small subunit NP_712538.1 2333339 D 189518 CDS NP_712541.2 294828088 1151703 2334578..2338183 1 NC_004342.2 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2338183 nrdA 1151703 nrdA Leptospira interrogans serovar Lai str. 56601 ribonucleotide-diphosphate reductase subunit alpha NP_712541.2 2334578 D 189518 CDS NP_712542.1 24215061 1151704 complement(2338353..2338898) 1 NC_004342.2 alcohol dehydrogenase 2338898 tdh 1151704 tdh Leptospira interrogans serovar Lai str. 56601 alcohol dehydrogenase NP_712542.1 2338353 R 189518 CDS NP_712543.2 294828089 1151705 complement(2339383..2339595) 1 NC_004342.2 hypothetical protein 2339595 1151705 LA_2362 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712543.2 2339383 R 189518 CDS NP_712546.1 24215065 1151708 complement(2340140..2341081) 1 NC_004342.2 hypothetical protein 2341081 1151708 LA_2365 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712546.1 2340140 R 189518 CDS NP_712547.1 24215066 1151709 complement(2341078..2341605) 1 NC_004342.2 hypothetical protein 2341605 1151709 LA_2366 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712547.1 2341078 R 189518 CDS NP_712548.1 24215067 1151710 complement(2341613..2343235) 1 NC_004342.2 ATPase 2343235 1151710 LA_2367 Leptospira interrogans serovar Lai str. 56601 ATPase NP_712548.1 2341613 R 189518 CDS NP_712549.2 294828090 1151711 complement(2343241..2344506) 1 NC_004342.2 type II secretion pathway related protein etpK-like protein 2344506 1151711 LA_2368 Leptospira interrogans serovar Lai str. 56601 type II secretion pathway related protein etpK-like protein NP_712549.2 2343241 R 189518 CDS NP_712550.1 24215069 1151712 complement(2344580..2345224) 1 NC_004342.2 type II secretory pathway component 2345224 1151712 LA_2369 Leptospira interrogans serovar Lai str. 56601 type II secretory pathway component NP_712550.1 2344580 R 189518 CDS NP_712551.1 24215070 1151713 complement(2345234..2345770) 1 NC_004342.2 hypothetical protein 2345770 1151713 LA_2370 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712551.1 2345234 R 189518 CDS NP_712552.2 294828091 1151714 complement(2345745..2346266) 1 NC_004342.2 hypothetical protein 2346266 1151714 LA_2371 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712552.2 2345745 R 189518 CDS NP_712553.1 24215072 1151715 complement(2346336..2346812) 1 NC_004342.2 type II secretory pathway component protein G 2346812 gspG 1151715 gspG Leptospira interrogans serovar Lai str. 56601 type II secretory pathway component protein G NP_712553.1 2346336 R 189518 CDS NP_712554.1 24215073 1151716 complement(2346834..2348060) 1 NC_004342.2 type II secretory pathway component protein F 2348060 gspF 1151716 gspF Leptospira interrogans serovar Lai str. 56601 type II secretory pathway component protein F NP_712554.1 2346834 R 189518 CDS NP_712555.1 24215074 1151717 complement(2348066..2349739) 1 NC_004342.2 type II secretory pathway ATPase protein E 2349739 gspE 1151717 gspE Leptospira interrogans serovar Lai str. 56601 type II secretory pathway ATPase protein E NP_712555.1 2348066 R 189518 CDS NP_712556.2 294828092 1151718 complement(2349743..2351533) 1 NC_004342.2 type II secretory pathway component protein D 2351533 gspD 1151718 gspD Leptospira interrogans serovar Lai str. 56601 type II secretory pathway component protein D NP_712556.2 2349743 R 189518 CDS NP_712557.1 24215076 1151719 complement(2351538..2352446) 1 NC_004342.2 type II secretory pathway component protein C 2352446 gspC 1151719 gspC Leptospira interrogans serovar Lai str. 56601 type II secretory pathway component protein C NP_712557.1 2351538 R 189518 CDS NP_712558.2 294828093 1151720 complement(2352502..2353506) 1 NC_004342.2 M23 family metalloendopeptidase 2353506 nlpD 1151720 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_712558.2 2352502 R 189518 CDS NP_712559.2 294828094 1151721 complement(2353481..2353789) 1 NC_004342.2 hypothetical protein 2353789 1151721 LA_2378 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712559.2 2353481 R 189518 CDS NP_712560.2 294828095 1151722 2354014..2355543 1 NC_004342.2 Mg chelatase subunit ChII 2355543 1151722 LA_2379 Leptospira interrogans serovar Lai str. 56601 Mg chelatase subunit ChII NP_712560.2 2354014 D 189518 CDS NP_712561.1 24215080 1151723 complement(2355563..2355760) 1 NC_004342.2 hypothetical protein 2355760 1151723 LA_2380 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712561.1 2355563 R 189518 CDS NP_712562.1 24215081 1151724 complement(2355856..2356206) 1 NC_004342.2 hypothetical protein 2356206 1151724 LA_2381 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712562.1 2355856 R 189518 CDS NP_712564.1 24215083 1151726 complement(2356922..2358106) 1 NC_004342.2 response regulator with HD-GYP domain 2358106 1151726 LA_2383 Leptospira interrogans serovar Lai str. 56601 response regulator with HD-GYP domain NP_712564.1 2356922 R 189518 CDS NP_712565.1 24215084 1151727 complement(2358103..2358366) 1 NC_004342.2 FlhB-like protein 2358366 1151727 LA_2384 Leptospira interrogans serovar Lai str. 56601 FlhB-like protein NP_712565.1 2358103 R 189518 CDS NP_712566.1 24215085 1151728 complement(2358367..2359110) 1 NC_004342.2 hypothetical protein 2359110 1151728 LA_2385 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712566.1 2358367 R 189518 CDS NP_712567.2 294828096 1151729 complement(2359184..2359879) 1 NC_004342.2 ribonuclease H II 2359879 rnhB 1151729 rnhB Leptospira interrogans serovar Lai str. 56601 ribonuclease H II NP_712567.2 2359184 R 189518 CDS NP_712568.1 24215087 1151730 complement(2359886..2360302) 1 NC_004342.2 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2360302 rplS 1151730 rplS Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L19 NP_712568.1 2359886 R 189518 CDS NP_712569.1 24215088 1151731 complement(2360262..2360957) 1 NC_004342.2 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; Chlamydial proteins show a C-terminal extension of unknown function; tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein 2360957 trmD 1151731 trmD Leptospira interrogans serovar Lai str. 56601 tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein NP_712569.1 2360262 R 189518 CDS NP_712570.1 24215089 1151732 complement(2360947..2361477) 1 NC_004342.2 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2361477 rimM 1151732 rimM Leptospira interrogans serovar Lai str. 56601 16S rRNA-processing protein RimM NP_712570.1 2360947 R 189518 CDS NP_712571.1 24215090 1151733 complement(2361470..2361700) 1 NC_004342.2 RNA-binding protein 2361700 1151733 LA_2390 Leptospira interrogans serovar Lai str. 56601 RNA-binding protein NP_712571.1 2361470 R 189518 CDS NP_712572.3 294828097 1151734 complement(2361700..2362044) 1 NC_004342.2 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2362044 rpsP 1151734 rpsP Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S16 NP_712572.3 2361700 R 189518 CDS NP_712575.1 24215094 1151737 complement(2362740..2363387) 1 NC_004342.2 ribulose-5-phosphate 3-epimerase 2363387 rpe 1151737 rpe Leptospira interrogans serovar Lai str. 56601 ribulose-5-phosphate 3-epimerase NP_712575.1 2362740 R 189518 CDS NP_712576.1 24215095 1151738 complement(2363384..2364379) 1 NC_004342.2 hypothetical protein 2364379 1151738 LA_2395 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712576.1 2363384 R 189518 CDS NP_712577.2 294828098 1151739 complement(2364376..2365323) 1 NC_004342.2 methionyl-tRNA formyltransferase 2365323 fmt 1151739 fmt Leptospira interrogans serovar Lai str. 56601 methionyl-tRNA formyltransferase NP_712577.2 2364376 R 189518 CDS NP_712579.1 24215098 1151741 complement(2365450..2367393) 1 NC_004342.2 primosomal protein N 2367393 priA 1151741 priA Leptospira interrogans serovar Lai str. 56601 primosomal protein N NP_712579.1 2365450 R 189518 CDS NP_712580.1 24215099 1151742 complement(2367390..2368241) 1 NC_004342.2 hypothetical protein 2368241 1151742 LA_2399 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712580.1 2367390 R 189518 CDS NP_712581.1 24215100 1151743 complement(2368234..2369580) 1 NC_004342.2 response regulator of two component system 2369580 atoC 1151743 atoC Leptospira interrogans serovar Lai str. 56601 response regulator of two component system NP_712581.1 2368234 R 189518 CDS NP_712582.1 24215101 1151744 complement(2369588..2371378) 1 NC_004342.2 histidine kinase sensor protein 2371378 1151744 LA_2401 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_712582.1 2369588 R 189518 CDS NP_712583.1 24215102 1151745 complement(2371392..2371655) 1 NC_004342.2 phosphocarrier protein Hpr 2371655 fruB 1151745 fruB Leptospira interrogans serovar Lai str. 56601 phosphocarrier protein Hpr NP_712583.1 2371392 R 189518 CDS NP_712584.1 24215103 1151746 complement(2371627..2372592) 1 NC_004342.2 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 2372592 hprK 1151746 hprK Leptospira interrogans serovar Lai str. 56601 HPr kinase/phosphorylase NP_712584.1 2371627 R 189518 CDS NP_712585.1 24215104 1151747 complement(2372597..2374018) 1 NC_004342.2 DNA-directed RNA polymerase sigma-54 subunit 2374018 rpoN 1151747 rpoN Leptospira interrogans serovar Lai str. 56601 DNA-directed RNA polymerase sigma-54 subunit NP_712585.1 2372597 R 189518 CDS NP_712586.2 294828099 1151748 complement(2374015..2374722) 1 NC_004342.2 ABC transporter ATP-binding protein 2374722 yhbG 1151748 yhbG Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_712586.2 2374015 R 189518 CDS NP_712587.1 24215106 1151749 complement(2374753..2376123) 1 NC_004342.2 hypothetical protein 2376123 1151749 LA_2406 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712587.1 2374753 R 189518 CDS NP_712588.1 24215107 1151750 complement(2376120..2376704) 1 NC_004342.2 hypothetical protein 2376704 1151750 LA_2407 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712588.1 2376120 R 189518 CDS NP_712589.2 294828100 1151751 complement(2376716..2377579) 1 NC_004342.2 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 2377579 kdsA 1151751 kdsA Leptospira interrogans serovar Lai str. 56601 2-dehydro-3-deoxyphosphooctonate aldolase NP_712589.2 2376716 R 189518 CDS NP_712590.2 294828101 1151752 complement(2377582..2379198) 1 NC_004342.2 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2379198 pyrG 1151752 pyrG Leptospira interrogans serovar Lai str. 56601 CTP synthetase NP_712590.2 2377582 R 189518 CDS NP_712591.1 24215110 1151753 complement(2379397..2379873) 1 NC_004342.2 glycerol-3-phosphate cytidylyltransferase 2379873 1151753 LA_2410 Leptospira interrogans serovar Lai str. 56601 glycerol-3-phosphate cytidylyltransferase NP_712591.1 2379397 R 189518 CDS NP_712592.1 24215111 1151754 complement(2379874..2380887) 1 NC_004342.2 ADP-heptose synthetase 2380887 rfaE 1151754 rfaE Leptospira interrogans serovar Lai str. 56601 ADP-heptose synthetase NP_712592.1 2379874 R 189518 CDS NP_712593.2 294828102 1151755 2380996..2381562 1 NC_004342.2 ATP-dependent Lon protease 2381562 1151755 LA_2412 Leptospira interrogans serovar Lai str. 56601 ATP-dependent Lon protease NP_712593.2 2380996 D 189518 CDS NP_712594.1 24215113 1151756 complement(2381854..2383125) 1 NC_004342.2 cell wall-associated hydrolase/lipoprotein 2383125 1151756 LA_2413 Leptospira interrogans serovar Lai str. 56601 cell wall-associated hydrolase/lipoprotein NP_712594.1 2381854 R 189518 CDS NP_712595.1 24215114 1151757 complement(2383175..2384479) 1 NC_004342.2 dipeptide/tripeptide permease 2384479 ptr2 1151757 ptr2 Leptospira interrogans serovar Lai str. 56601 dipeptide/tripeptide permease NP_712595.1 2383175 R 189518 CDS NP_712596.1 24215115 1151758 complement(2384455..2385006) 1 NC_004342.2 cobalamin adenosyltransferase 2385006 1151758 LA_2415 Leptospira interrogans serovar Lai str. 56601 cobalamin adenosyltransferase NP_712596.1 2384455 R 189518 CDS NP_712598.2 294828103 1151760 2385344..2386195 1 NC_004342.2 endoflagellar hook-filament protein 2386195 flgL 1151760 flgL Leptospira interrogans serovar Lai str. 56601 endoflagellar hook-filament protein NP_712598.2 2385344 D 189518 CDS NP_712599.1 24215118 1151761 complement(2386774..2387622) 1 NC_004342.2 endoflagellar filament core protein 2387622 1151761 LA_2418 Leptospira interrogans serovar Lai str. 56601 endoflagellar filament core protein NP_712599.1 2386774 R 189518 CDS NP_712600.2 294828104 1151762 2388080..2388694 1 NC_004342.2 hypothetical protein 2388694 1151762 LA_2419 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712600.2 2388080 D 189518 CDS NP_712601.2 294828105 1151763 2388870..2389808 1 NC_004342.2 penicillin tolerance protein 2389808 lytB 1151763 lytB Leptospira interrogans serovar Lai str. 56601 penicillin tolerance protein NP_712601.2 2388870 D 189518 CDS NP_712602.1 24215121 1151764 2390398..2392593 1 NC_004342.2 histidine kinase sensor protein 2392593 1151764 LA_2421 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_712602.1 2390398 D 189518 CDS NP_712603.2 294828106 1151765 2392556..2393818 1 NC_004342.2 histidine kinase/response regulator hybrid protein 2393818 1151765 LA_2422 Leptospira interrogans serovar Lai str. 56601 histidine kinase/response regulator hybrid protein NP_712603.2 2392556 D 189518 CDS NP_712604.2 294828107 1151766 2393832..2394194 1 NC_004342.2 chemotaxis response regulator CheY 2394194 1151766 LA_2423 Leptospira interrogans serovar Lai str. 56601 chemotaxis response regulator CheY NP_712604.2 2393832 D 189518 CDS NP_712605.2 294828108 1151767 2394203..2394565 1 NC_004342.2 anti-sigma factor antagonist 2394565 1151767 LA_2424 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_712605.2 2394203 D 189518 CDS NP_712606.1 24215125 1151768 2394569..2396710 1 NC_004342.2 chemotaxis protein histidine kinase CheA 2396710 cheA 1151768 cheA Leptospira interrogans serovar Lai str. 56601 chemotaxis protein histidine kinase CheA NP_712606.1 2394569 D 189518 CDS NP_712607.1 24215126 1151769 2396755..2399685 1 NC_004342.2 methyl-accepting chemotaxis protein 2399685 1151769 LA_2426 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_712607.1 2396755 D 189518 CDS NP_712608.1 24215127 1151770 2399698..2400213 1 NC_004342.2 chemotaxis protein CheW 2400213 cheW 1151770 cheW Leptospira interrogans serovar Lai str. 56601 chemotaxis protein CheW NP_712608.1 2399698 D 189518 CDS NP_712609.1 24215128 1151771 2400210..2400710 1 NC_004342.2 chemotaxis protein CheD 2400710 cheD 1151771 cheD Leptospira interrogans serovar Lai str. 56601 chemotaxis protein CheD NP_712609.1 2400210 D 189518 CDS NP_712610.1 24215129 1151772 2400707..2401750 1 NC_004342.2 chemotaxis-specific methylesterase CheB 2401750 cheB 1151772 cheB Leptospira interrogans serovar Lai str. 56601 chemotaxis-specific methylesterase CheB NP_712610.1 2400707 D 189518 CDS NP_712611.1 24215130 1151773 complement(2401765..2401899) 1 NC_004342.2 hypothetical protein 2401899 1151773 LA_2430 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712611.1 2401765 R 189518 CDS YP_003573324.1 294828109 9006925 2402297..2402506 1 NC_004342.2 hypothetical protein 2402506 9006925 LA_2430a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573324.1 2402297 D 189518 CDS NP_712613.1 24215132 1151775 complement(2402580..2405324) 1 NC_004342.2 biotin carboxylase-like protein 2405324 1151775 LA_2432 Leptospira interrogans serovar Lai str. 56601 biotin carboxylase-like protein NP_712613.1 2402580 R 189518 CDS NP_712614.1 24215133 1151776 complement(2405331..2406998) 1 NC_004342.2 acetyl-CoA carboxylase carboxyltransferase component 2406998 1151776 LA_2433 Leptospira interrogans serovar Lai str. 56601 acetyl-CoA carboxylase carboxyltransferase component NP_712614.1 2405331 R 189518 CDS NP_712615.1 24215134 1151777 complement(2407075..2407404) 1 NC_004342.2 anti-sigma factor antagonist 2407404 spoIIAA 1151777 spoIIAA Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_712615.1 2407075 R 189518 CDS NP_712616.1 24215135 1151778 complement(2407388..2410204) 1 NC_004342.2 serine/threonine phosphatase 2410204 1151778 LA_2435 Leptospira interrogans serovar Lai str. 56601 serine/threonine phosphatase NP_712616.1 2407388 R 189518 CDS NP_712617.2 294828110 1151779 complement(2410219..2410527) 1 NC_004342.2 hypothetical protein 2410527 1151779 LA_2436 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712617.2 2410219 R 189518 CDS NP_712618.1 24215137 1151780 2410817..2411497 1 NC_004342.2 hypothetical protein 2411497 1151780 LA_2437 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712618.1 2410817 D 189518 CDS NP_712619.1 24215138 1151781 2411500..2412036 1 NC_004342.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 2412036 def 1151781 def Leptospira interrogans serovar Lai str. 56601 peptide deformylase NP_712619.1 2411500 D 189518 CDS NP_712620.1 24215139 1151782 2412056..2415298 1 NC_004342.2 heavy metal efflux pump 2415298 1151782 LA_2439 Leptospira interrogans serovar Lai str. 56601 heavy metal efflux pump NP_712620.1 2412056 D 189518 CDS NP_712621.1 24215140 1151783 complement(2415450..2416532) 1 NC_004342.2 cytoplasmic membrane protein 2416532 1151783 LA_2440 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_712621.1 2415450 R 189518 CDS NP_712624.2 294828111 1151786 complement(2420416..2421882) 1 NC_004342.2 hypothetical protein 2421882 1151786 LA_2443 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712624.2 2420416 R 189518 CDS NP_712625.2 294828112 1151787 complement(2422084..2423055) 1 NC_004342.2 hypothetical protein 2423055 1151787 LA_2444 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712625.2 2422084 R 189518 CDS YP_003573325.1 294828113 9006928 complement(2423188..2423373) 1 NC_004342.2 hypothetical protein 2423373 9006928 LA_2444a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573325.1 2423188 R 189518 CDS NP_712629.1 24215148 1151791 complement(2425401..2426687) 1 NC_004342.2 hypothetical protein 2426687 1151791 LA_2448 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712629.1 2425401 R 189518 CDS NP_712631.1 24215150 1151793 complement(2426897..2428798) 1 NC_004342.2 hypothetical protein 2428798 1151793 LA_2450 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712631.1 2426897 R 189518 CDS NP_712633.2 294828114 1151795 complement(2429008..2429805) 1 NC_004342.2 cytoplasmic membrane protein 2429805 1151795 LA_2452 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_712633.2 2429008 R 189518 CDS NP_712634.1 24215153 1151796 complement(2430207..2431145) 1 NC_004342.2 (4Fe-4S)-binding protein 2431145 1151796 LA_2453 Leptospira interrogans serovar Lai str. 56601 (4Fe-4S)-binding protein NP_712634.1 2430207 R 189518 CDS NP_712635.2 294828115 1151797 2431166..2431600 1 NC_004342.2 hypothetical protein 2431600 1151797 LA_2454 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712635.2 2431166 D 189518 CDS NP_712637.1 24215156 1151799 complement(2432606..2433523) 1 NC_004342.2 hypothetical protein 2433523 1151799 LA_2456 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712637.1 2432606 R 189518 CDS NP_712638.2 294828116 1151800 complement(2433534..2434256) 1 NC_004342.2 methionyl aminopeptidase 2434256 map 1151800 map Leptospira interrogans serovar Lai str. 56601 methionyl aminopeptidase NP_712638.2 2433534 R 189518 CDS NP_712639.2 294828117 1151801 complement(2434299..2434493) 1 NC_004342.2 hypothetical protein 2434493 1151801 LA_2458 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712639.2 2434299 R 189518 CDS NP_712640.1 24215159 1151802 complement(2434781..2438194) 1 NC_004342.2 SMC-like protein 2438194 1151802 LA_2459 Leptospira interrogans serovar Lai str. 56601 SMC-like protein NP_712640.1 2434781 R 189518 CDS NP_712641.1 24215160 1151803 2438435..2439214 1 NC_004342.2 methyltransferase 2439214 1151803 LA_2460 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_712641.1 2438435 D 189518 CDS NP_712642.1 24215161 1151804 2439295..2439591 1 NC_004342.2 anti-Sigma factor antagonist 2439591 1151804 LA_2461 Leptospira interrogans serovar Lai str. 56601 anti-Sigma factor antagonist NP_712642.1 2439295 D 189518 CDS NP_712643.1 24215162 1151805 2439651..2440589 1 NC_004342.2 ABC transporter ATP-binding protein 2440589 ccmA 1151805 ccmA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_712643.1 2439651 D 189518 CDS NP_712644.1 24215163 1151806 2440570..2441316 1 NC_004342.2 gliding motility ABC transporter 2441316 1151806 LA_2463 Leptospira interrogans serovar Lai str. 56601 gliding motility ABC transporter NP_712644.1 2440570 D 189518 CDS NP_712645.1 24215164 1151807 2441313..2443019 1 NC_004342.2 gliding motility ABC transporter 2443019 1151807 LA_2464 Leptospira interrogans serovar Lai str. 56601 gliding motility ABC transporter NP_712645.1 2441313 D 189518 CDS NP_712646.1 24215165 1151808 2443016..2444026 1 NC_004342.2 hypothetical protein 2444026 1151808 LA_2465 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712646.1 2443016 D 189518 CDS NP_712647.1 24215166 1151809 2444457..2445209 1 NC_004342.2 methyltransferase 2445209 ste14 1151809 ste14 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_712647.1 2444457 D 189518 CDS NP_712648.1 24215167 1151810 complement(2445904..2446653) 1 NC_004342.2 hypothetical protein 2446653 1151810 LA_2467 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712648.1 2445904 R 189518 CDS NP_712649.1 24215168 1151811 2446657..2447991 1 NC_004342.2 hypothetical protein 2447991 1151811 LA_2468 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712649.1 2446657 D 189518 CDS NP_712650.1 24215169 1151812 2447991..2448455 1 NC_004342.2 MCP methylation inhibitor 2448455 1151812 LA_2469 Leptospira interrogans serovar Lai str. 56601 MCP methylation inhibitor NP_712650.1 2447991 D 189518 CDS NP_712651.1 24215170 1151813 2448897..2449448 1 NC_004342.2 hypothetical protein 2449448 1151813 LA_2470 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712651.1 2448897 D 189518 CDS NP_712652.1 24215171 1151814 complement(2449710..2450705) 1 NC_004342.2 hypothetical protein 2450705 1151814 LA_2471 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712652.1 2449710 R 189518 CDS NP_712653.1 24215172 1151815 complement(2450702..2451292) 1 NC_004342.2 hypothetical protein 2451292 1151815 LA_2472 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712653.1 2450702 R 189518 CDS NP_712654.1 24215173 1151816 2451455..2452150 1 NC_004342.2 transcriptional regulatory protein 2452150 1151816 LA_2473 Leptospira interrogans serovar Lai str. 56601 transcriptional regulatory protein NP_712654.1 2451455 D 189518 CDS NP_712656.2 294828118 1151818 2452494..2454212 1 NC_004342.2 polymerase 2454212 1151818 LA_2474 Leptospira interrogans serovar Lai str. 56601 polymerase NP_712656.2 2452494 D 189518 CDS NP_712658.1 24215177 1151820 complement(2454575..2454940) 1 NC_004342.2 TfoX-like protein 2454940 tfoX 1151820 tfoX Leptospira interrogans serovar Lai str. 56601 TfoX-like protein NP_712658.1 2454575 R 189518 CDS NP_712659.2 294828119 1151821 complement(2455013..2455387) 1 NC_004342.2 hypothetical protein 2455387 1151821 LA_2478 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712659.2 2455013 R 189518 CDS NP_712660.2 294828120 1151822 complement(2455408..2455836) 1 NC_004342.2 anti-sigma factor antagonist 2455836 rsbW 1151822 rsbW Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_712660.2 2455408 R 189518 CDS NP_712664.1 24215183 1151826 complement(2456330..2457226) 1 NC_004342.2 integrase/recombinase XerD 2457226 xerD 1151826 xerD Leptospira interrogans serovar Lai str. 56601 integrase/recombinase XerD NP_712664.1 2456330 R 189518 CDS NP_712665.1 24215184 1151827 2457324..2458199 1 NC_004342.2 hypothetical protein 2458199 1151827 LA_2484 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712665.1 2457324 D 189518 CDS NP_712667.1 24215186 1151829 2458330..2459358 1 NC_004342.2 hypothetical protein 2459358 1151829 LA_2486 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712667.1 2458330 D 189518 CDS NP_712669.1 24215188 1151831 2459949..2460488 1 NC_004342.2 hypothetical protein 2460488 1151831 LA_2488 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712669.1 2459949 D 189518 CDS NP_712670.1 24215189 1151832 complement(2460535..2461971) 1 NC_004342.2 MBOAT family D-alaninealginate export/acetyltransferase membrane protein 2461971 dltB 1151832 dltB Leptospira interrogans serovar Lai str. 56601 MBOAT family D-alaninealginate export/acetyltransferase membrane protein NP_712670.1 2460535 R 189518 CDS NP_712671.2 294828121 1151833 complement(2461961..2463301) 1 NC_004342.2 hypothetical protein 2463301 1151833 LA_2490 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712671.2 2461961 R 189518 CDS NP_712673.2 294828122 1151835 2464085..2464381 1 NC_004342.2 ISlin1 transposase 2464381 1151835 LA_2492 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_712673.2 2464085 D 189518 CDS NP_712674.1 24215193 1151836 2464350..2465264 1 NC_004342.2 ISlin1 transposase 2465264 1151836 LA_2493 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_712674.1 2464350 D 189518 CDS NP_712675.1 24215194 1151837 2466428..2467378 1 NC_004342.2 thioredoxin reductase 2467378 trxB 1151837 trxB Leptospira interrogans serovar Lai str. 56601 thioredoxin reductase NP_712675.1 2466428 D 189518 CDS NP_712677.1 24215196 1151839 complement(2469277..2469870) 1 NC_004342.2 hypothetical protein 2469870 1151839 LA_2496 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712677.1 2469277 R 189518 CDS NP_712678.2 294828123 1151840 complement(2469921..2471375) 1 NC_004342.2 hypothetical protein 2471375 1151840 LA_2497 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712678.2 2469921 R 189518 CDS NP_712679.1 24215198 1151841 2471547..2473067 1 NC_004342.2 regulator of chromosome condensation 2473067 ats1 1151841 ats1 Leptospira interrogans serovar Lai str. 56601 regulator of chromosome condensation NP_712679.1 2471547 D 189518 CDS NP_712680.2 294828124 1151842 2473137..2474585 1 NC_004342.2 thiol oxidoreductase 2474585 1151842 LA_2499 Leptospira interrogans serovar Lai str. 56601 thiol oxidoreductase NP_712680.2 2473137 D 189518 CDS NP_712682.1 24215201 1151844 2476230..2477123 1 NC_004342.2 hydrolase 2477123 mhpC 1151844 mhpC Leptospira interrogans serovar Lai str. 56601 hydrolase NP_712682.1 2476230 D 189518 CDS NP_712684.1 24215203 1151846 complement(2477525..2477698) 1 NC_004342.2 hypothetical protein 2477698 1151846 LA_2503 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712684.1 2477525 R 189518 CDS NP_712686.1 24215205 1151848 2478440..2479549 1 NC_004342.2 esterase/lipase 2479549 1151848 LA_2505 Leptospira interrogans serovar Lai str. 56601 esterase/lipase NP_712686.1 2478440 D 189518 CDS NP_712687.1 24215206 1151849 complement(2480175..2480945) 1 NC_004342.2 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2480945 hisF 1151849 hisF Leptospira interrogans serovar Lai str. 56601 imidazole glycerol phosphate synthase subunit HisF NP_712687.1 2480175 R 189518 CDS NP_712688.1 24215207 1151850 complement(2480942..2482405) 1 NC_004342.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 2482405 gatA 1151850 gatA Leptospira interrogans serovar Lai str. 56601 aspartyl/glutamyl-tRNA amidotransferase subunit A NP_712688.1 2480942 R 189518 CDS NP_712689.1 24215208 1151851 complement(2482402..2482692) 1 NC_004342.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 2482692 gatC 1151851 gatC Leptospira interrogans serovar Lai str. 56601 aspartyl/glutamyl-tRNA amidotransferase subunit C NP_712689.1 2482402 R 189518 CDS NP_712690.2 294828125 1151852 complement(2482719..2484134) 1 NC_004342.2 glycosyltransferase 2484134 wcaJ 1151852 wcaJ Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_712690.2 2482719 R 189518 CDS NP_712691.1 24215210 1151853 complement(2484137..2487112) 1 NC_004342.2 hypothetical protein 2487112 1151853 LA_2510 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712691.1 2484137 R 189518 CDS NP_712692.1 24215211 1151854 complement(2487136..2487969) 1 NC_004342.2 undecaprenol kinase 2487969 bacA 1151854 bacA Leptospira interrogans serovar Lai str. 56601 undecaprenol kinase NP_712692.1 2487136 R 189518 CDS NP_712693.1 24215212 1151855 complement(2487976..2488701) 1 NC_004342.2 cytoplasmic membrane lipoprotein LipL31 2488701 lipL31 1151855 lipL31 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane lipoprotein LipL31 NP_712693.1 2487976 R 189518 CDS NP_712694.1 24215213 1151856 complement(2488748..2492308) 1 NC_004342.2 transcription-repair coupling factor 2492308 mfd 1151856 mfd Leptospira interrogans serovar Lai str. 56601 transcription-repair coupling factor NP_712694.1 2488748 R 189518 CDS NP_712695.1 24215214 1151857 complement(2492305..2493162) 1 NC_004342.2 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 2493162 panC 1151857 panC Leptospira interrogans serovar Lai str. 56601 pantoate--beta-alanine ligase NP_712695.1 2492305 R 189518 CDS NP_712696.1 24215215 1151858 complement(2493193..2494476) 1 NC_004342.2 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2494476 hisD 1151858 hisD Leptospira interrogans serovar Lai str. 56601 histidinol dehydrogenase NP_712696.1 2493193 R 189518 CDS NP_712697.2 294828126 1151859 2494576..2495340 1 NC_004342.2 exodeoxyribonuclease 2495340 xthA 1151859 xthA Leptospira interrogans serovar Lai str. 56601 exodeoxyribonuclease NP_712697.2 2494576 D 189518 CDS NP_712699.2 294828127 1151861 2496764..2497933 1 NC_004342.2 ISlin1 transposase 2497933 1151861 LA_2518 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_712699.2 2496764 D 189518 CDS NP_712700.2 294828128 1151862 complement(2498248..2498694) 1 NC_004342.2 hypothetical protein 2498694 1151862 LA_2519 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712700.2 2498248 R 189518 CDS NP_712705.2 294828129 1151867 2500965..2502134 1 NC_004342.2 ISlin1 transposase 2502134 1151867 LA_2524 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_712705.2 2500965 D 189518 CDS NP_712707.1 24215226 1151869 complement(2502756..2503646) 1 NC_004342.2 hydrolase 2503646 1151869 LA_2526 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_712707.1 2502756 R 189518 CDS NP_712708.1 24215227 1151870 2504351..2505694 1 NC_004342.2 glycerate kinase 2505694 gckA 1151870 gckA Leptospira interrogans serovar Lai str. 56601 glycerate kinase NP_712708.1 2504351 D 189518 CDS NP_712709.1 24215228 1151871 complement(2505983..2506975) 1 NC_004342.2 GGDEF domain receiver component of a two component response regulator 2506975 pleD 1151871 pleD Leptospira interrogans serovar Lai str. 56601 GGDEF domain receiver component of a two component response regulator NP_712709.1 2505983 R 189518 CDS NP_712710.1 24215229 1151872 2507119..2507505 1 NC_004342.2 hypothetical protein 2507505 1151872 LA_2529 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712710.1 2507119 D 189518 CDS NP_712711.1 24215230 1151873 2507558..2508016 1 NC_004342.2 hypothetical protein 2508016 1151873 LA_2530 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712711.1 2507558 D 189518 CDS NP_712712.2 294828130 1151874 2508031..2508462 1 NC_004342.2 hypothetical protein 2508462 1151874 LA_2531 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712712.2 2508031 D 189518 CDS NP_712713.1 24215232 1151875 complement(2509684..2511135) 1 NC_004342.2 histidine kinase/response regulator hybrid protein 2511135 1151875 LA_2532 Leptospira interrogans serovar Lai str. 56601 histidine kinase/response regulator hybrid protein NP_712713.1 2509684 R 189518 CDS NP_712714.2 294828131 1151876 complement(2511158..2512189) 1 NC_004342.2 histidine kinase sensor protein 2512189 1151876 LA_2533 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_712714.2 2511158 R 189518 CDS NP_712716.1 24215235 1151878 complement(2513995..2514453) 1 NC_004342.2 peptidyl-prolyl cis-trans isomerase 2514453 ppiB 1151878 ppiB Leptospira interrogans serovar Lai str. 56601 peptidyl-prolyl cis-trans isomerase NP_712716.1 2513995 R 189518 CDS NP_712717.1 24215236 1151879 2514654..2517536 1 NC_004342.2 guanylate cyclase 2517536 1151879 LA_2536 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_712717.1 2514654 D 189518 CDS NP_712718.1 24215237 1151880 2517520..2519637 1 NC_004342.2 hypothetical protein 2519637 1151880 LA_2537 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712718.1 2517520 D 189518 CDS NP_712719.1 24215238 1151881 2519627..2520751 1 NC_004342.2 hypothetical protein 2520751 1151881 LA_2538 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712719.1 2519627 D 189518 CDS NP_712720.1 24215239 1151882 complement(2521395..2523266) 1 NC_004342.2 ABC transporter ATPase 2523266 uup 1151882 uup Leptospira interrogans serovar Lai str. 56601 ABC transporter ATPase NP_712720.1 2521395 R 189518 CDS NP_712721.2 294828132 1151883 complement(2523309..2524715) 1 NC_004342.2 signal transduction histidine kinase 2524715 1151883 LA_2540 Leptospira interrogans serovar Lai str. 56601 signal transduction histidine kinase NP_712721.2 2523309 R 189518 CDS NP_712722.2 294828133 1151884 2525015..2528068 1 NC_004342.2 histidine kinase/response regulator hybrid protein 2528068 1151884 LA_2541 Leptospira interrogans serovar Lai str. 56601 histidine kinase/response regulator hybrid protein NP_712722.2 2525015 D 189518 CDS NP_712723.1 24215242 1151885 complement(2528144..2528620) 1 NC_004342.2 cAMP-binding protein 2528620 crp 1151885 crp Leptospira interrogans serovar Lai str. 56601 cAMP-binding protein NP_712723.1 2528144 R 189518 CDS NP_712725.1 24215244 1151887 2529199..2530188 1 NC_004342.2 alpha/beta hydrolase 2530188 1151887 LA_2544 Leptospira interrogans serovar Lai str. 56601 alpha/beta hydrolase NP_712725.1 2529199 D 189518 CDS NP_712726.1 24215245 1151888 complement(2530470..2531567) 1 NC_004342.2 hypothetical protein 2531567 1151888 LA_2545 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712726.1 2530470 R 189518 CDS NP_712727.1 24215246 1151889 complement(2531564..2532025) 1 NC_004342.2 capsule biosynthesis protein 2532025 1151889 LA_2546 Leptospira interrogans serovar Lai str. 56601 capsule biosynthesis protein NP_712727.1 2531564 R 189518 CDS NP_712728.1 24215247 1151890 complement(2532013..2533236) 1 NC_004342.2 capsule biosynthesis protein 2533236 1151890 LA_2547 Leptospira interrogans serovar Lai str. 56601 capsule biosynthesis protein NP_712728.1 2532013 R 189518 CDS NP_712729.1 24215248 1151891 complement(2533238..2534494) 1 NC_004342.2 serine/threonine phosphatase 2534494 1151891 LA_2548 Leptospira interrogans serovar Lai str. 56601 serine/threonine phosphatase NP_712729.1 2533238 R 189518 CDS NP_712730.1 24215249 1151892 complement(2534555..2535676) 1 NC_004342.2 signal transduction histidine kinase 2535676 baeS 1151892 baeS Leptospira interrogans serovar Lai str. 56601 signal transduction histidine kinase NP_712730.1 2534555 R 189518 CDS NP_712731.1 24215250 1151893 complement(2535785..2536174) 1 NC_004342.2 FKBP-type peptidylprolyl isomerase 2536174 fkpA 1151893 fkpA Leptospira interrogans serovar Lai str. 56601 FKBP-type peptidylprolyl isomerase NP_712731.1 2535785 R 189518 CDS NP_712732.1 24215251 1151894 complement(2536171..2536566) 1 NC_004342.2 RNA-binding protein 2536566 1151894 LA_2551 Leptospira interrogans serovar Lai str. 56601 RNA-binding protein NP_712732.1 2536171 R 189518 CDS NP_712733.1 24215252 1151895 2536677..2537723 1 NC_004342.2 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 2537723 1151895 LA_2552 Leptospira interrogans serovar Lai str. 56601 serine/threonine protein kinase NP_712733.1 2536677 D 189518 CDS NP_712736.2 294828134 1151898 2538008..2540299 1 NC_004342.2 phosphate sodium symporter 2540299 1151898 LA_2554 Leptospira interrogans serovar Lai str. 56601 phosphate sodium symporter NP_712736.2 2538008 D 189518 CDS NP_712737.1 24215256 1151899 2540783..2541271 1 NC_004342.2 GNAT family N-acetyltransferase 2541271 1151899 LA_2556 Leptospira interrogans serovar Lai str. 56601 GNAT family N-acetyltransferase NP_712737.1 2540783 D 189518 CDS NP_712738.2 294828135 1151900 2541370..2541843 1 NC_004342.2 hypothetical protein 2541843 1151900 LA_2557 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712738.2 2541370 D 189518 CDS NP_712739.1 24215258 1151901 complement(2541855..2543117) 1 NC_004342.2 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 2543117 clpX 1151901 clpX Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease ATP-binding subunit ClpX NP_712739.1 2541855 R 189518 CDS NP_712740.1 24215259 1151902 complement(2543128..2543724) 1 NC_004342.2 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2543724 clpP 1151902 clpP Leptospira interrogans serovar Lai str. 56601 ATP-dependent Clp protease proteolytic subunit NP_712740.1 2543128 R 189518 CDS NP_712741.1 24215260 1151903 complement(2543721..2545076) 1 NC_004342.2 FKBP-type peptidylprolyl isomerase 2545076 tig 1151903 tig Leptospira interrogans serovar Lai str. 56601 FKBP-type peptidylprolyl isomerase NP_712741.1 2543721 R 189518 CDS NP_712742.2 294828136 1151904 complement(2545245..2545859) 1 NC_004342.2 acyl-CoA thioesterase 2545859 tesA 1151904 tesA Leptospira interrogans serovar Lai str. 56601 acyl-CoA thioesterase NP_712742.2 2545245 R 189518 CDS NP_712743.1 24215262 1151905 2545822..2547681 1 NC_004342.2 glycosylhydrolase 2547681 bglX 1151905 bglX Leptospira interrogans serovar Lai str. 56601 glycosylhydrolase NP_712743.1 2545822 D 189518 CDS NP_712744.1 24215263 1151906 2547678..2548844 1 NC_004342.2 coproporphyrinogen III oxidase 2548844 hemN 1151906 hemN Leptospira interrogans serovar Lai str. 56601 coproporphyrinogen III oxidase NP_712744.1 2547678 D 189518 CDS NP_712746.1 24215265 1151908 2549493..2549900 1 NC_004342.2 thioesterase 2549900 1151908 LA_2565 Leptospira interrogans serovar Lai str. 56601 thioesterase NP_712746.1 2549493 D 189518 CDS NP_712750.1 24215269 1151912 complement(2551005..2551490) 1 NC_004342.2 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 2551490 ilvH 1151912 ilvH Leptospira interrogans serovar Lai str. 56601 acetolactate synthase 3 regulatory subunit NP_712750.1 2551005 R 189518 CDS NP_712751.1 24215270 1151913 complement(2551487..2553265) 1 NC_004342.2 acetolactate synthase large subunit 2553265 ilvB 1151913 ilvB Leptospira interrogans serovar Lai str. 56601 acetolactate synthase large subunit NP_712751.1 2551487 R 189518 CDS NP_712753.1 24215272 1151915 2553626..2554735 1 NC_004342.2 TPR-repeat-containing protein 2554735 pilF 1151915 pilF Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_712753.1 2553626 D 189518 CDS NP_712755.1 24215274 1151917 2555284..2557824 1 NC_004342.2 methyl-accepting chemotaxis transmembrane protein 2557824 1151917 LA_2574 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis transmembrane protein NP_712755.1 2555284 D 189518 CDS NP_712756.1 24215275 1151918 2557905..2558174 1 NC_004342.2 hypothetical protein 2558174 1151918 LA_2575 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712756.1 2557905 D 189518 CDS NP_712757.1 24215276 1151919 complement(2558515..2560518) 1 NC_004342.2 hypothetical protein 2560518 1151919 LA_2576 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712757.1 2558515 R 189518 CDS NP_712758.2 294828137 1151920 2560690..2561982 1 NC_004342.2 protein kinase 2561982 aarF 1151920 aarF Leptospira interrogans serovar Lai str. 56601 protein kinase NP_712758.2 2560690 D 189518 CDS NP_712759.1 24215278 1151921 2561979..2562224 1 NC_004342.2 FeoA-like protein 2562224 feoA 1151921 feoA Leptospira interrogans serovar Lai str. 56601 FeoA-like protein NP_712759.1 2561979 D 189518 CDS NP_712760.1 24215279 1151922 2562211..2564316 1 NC_004342.2 ferrous iron transport protein B 2564316 feoB 1151922 feoB Leptospira interrogans serovar Lai str. 56601 ferrous iron transport protein B NP_712760.1 2562211 D 189518 CDS NP_712761.2 294828138 1151923 2564328..2566283 1 NC_004342.2 phosphoglycerol transferase-like protein 2566283 1151923 LA_2580 Leptospira interrogans serovar Lai str. 56601 phosphoglycerol transferase-like protein NP_712761.2 2564328 D 189518 CDS NP_712762.1 24215281 1151924 2566299..2567297 1 NC_004342.2 N-acetylneuraminic (sialic) acid synthetase 2567297 spsE 1151924 spsE Leptospira interrogans serovar Lai str. 56601 N-acetylneuraminic (sialic) acid synthetase NP_712762.1 2566299 D 189518 CDS NP_712763.1 24215282 1151925 2567290..2568432 1 NC_004342.2 M23 family metalloendopeptidase 2568432 nlpD 1151925 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_712763.1 2567290 D 189518 CDS NP_712765.1 24215284 1151927 complement(2568877..2569938) 1 NC_004342.2 hypothetical protein 2569938 1151927 LA_2584 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712765.1 2568877 R 189518 CDS NP_712768.1 24215287 1151930 2571357..2572277 1 NC_004342.2 hypothetical protein 2572277 1151930 LA_2587 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712768.1 2571357 D 189518 CDS NP_712769.1 24215288 1151931 complement(2573417..2573779) 1 NC_004342.2 hypothetical protein 2573779 1151931 LA_2588 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712769.1 2573417 R 189518 CDS NP_712770.1 24215289 1151932 complement(2573786..2574709) 1 NC_004342.2 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2574709 fliH 1151932 fliH Leptospira interrogans serovar Lai str. 56601 flagellar assembly protein H NP_712770.1 2573786 R 189518 CDS NP_712771.1 24215290 1151933 complement(2574713..2575684) 1 NC_004342.2 flagellar switch complex protein 2575684 fliG 1151933 fliG Leptospira interrogans serovar Lai str. 56601 flagellar switch complex protein NP_712771.1 2574713 R 189518 CDS NP_712772.1 24215291 1151934 complement(2575681..2577378) 1 NC_004342.2 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2577378 fliF 1151934 fliF Leptospira interrogans serovar Lai str. 56601 flagellar MS-ring protein NP_712772.1 2575681 R 189518 CDS NP_712773.1 24215292 1151935 2578645..2580009 1 NC_004342.2 endoflagellar biosynthesis/type III secretory pathway ATPase 2580009 fliI 1151935 fliI Leptospira interrogans serovar Lai str. 56601 endoflagellar biosynthesis/type III secretory pathway ATPase NP_712773.1 2578645 D 189518 CDS NP_712774.1 24215293 1151936 2580013..2580579 1 NC_004342.2 endoflagellar biosynthesis chaperone 2580579 1151936 LA_2593 Leptospira interrogans serovar Lai str. 56601 endoflagellar biosynthesis chaperone NP_712774.1 2580013 D 189518 CDS NP_712775.1 24215294 1151937 2580738..2581385 1 NC_004342.2 flagellar protein FlbB 2581385 1151937 LA_2594 Leptospira interrogans serovar Lai str. 56601 flagellar protein FlbB NP_712775.1 2580738 D 189518 CDS NP_712776.1 24215295 1151938 2581398..2581790 1 NC_004342.2 hypothetical protein 2581790 1151938 LA_2595 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712776.1 2581398 D 189518 CDS NP_712777.1 24215296 1151939 2581838..2582590 1 NC_004342.2 hypothetical protein 2582590 1151939 LA_2596 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712777.1 2581838 D 189518 CDS NP_712779.1 24215298 1151941 complement(2584081..2584368) 1 NC_004342.2 guanylate kinase 2584368 gmk 1151941 gmk Leptospira interrogans serovar Lai str. 56601 guanylate kinase NP_712779.1 2584081 R 189518 CDS NP_712780.1 24215299 1151942 complement(2584659..2584940) 1 NC_004342.2 hypothetical protein 2584940 1151942 LA_2599 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712780.1 2584659 R 189518 CDS NP_712781.2 294828139 1151943 complement(2584940..2585992) 1 NC_004342.2 hypothetical protein 2585992 1151943 LA_2600 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712781.2 2584940 R 189518 CDS NP_712782.1 24215301 1151944 complement(2586038..2586391) 1 NC_004342.2 hypothetical protein 2586391 1151944 LA_2601 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712782.1 2586038 R 189518 CDS NP_712783.1 24215302 1151945 complement(2586400..2588385) 1 NC_004342.2 polymerase 2588385 1151945 LA_2602 Leptospira interrogans serovar Lai str. 56601 polymerase NP_712783.1 2586400 R 189518 CDS NP_712784.1 24215303 1151946 complement(2588411..2589211) 1 NC_004342.2 involved in the initiation of sporulation and glycogen biosynthesis; RNA polymerase sigma factor WhiG 2589211 1151946 LA_2603 Leptospira interrogans serovar Lai str. 56601 RNA polymerase sigma factor WhiG NP_712784.1 2588411 R 189518 CDS NP_712785.1 24215304 1151947 complement(2589339..2589815) 1 NC_004342.2 hypothetical protein 2589815 1151947 LA_2604 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712785.1 2589339 R 189518 CDS NP_712786.1 24215305 1151948 complement(2589819..2590733) 1 NC_004342.2 ParA protein 2590733 1151948 LA_2605 Leptospira interrogans serovar Lai str. 56601 ParA protein NP_712786.1 2589819 R 189518 CDS NP_712787.2 294828140 1151949 complement(2590761..2592041) 1 NC_004342.2 Positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 2592041 1151949 LA_2606 Leptospira interrogans serovar Lai str. 56601 flagellar biosynthesis regulator FlhF NP_712787.2 2590761 R 189518 CDS NP_712788.1 24215307 1151950 complement(2592094..2594211) 1 NC_004342.2 endoflagellar biosynthesis protein 2594211 flhA 1151950 flhA Leptospira interrogans serovar Lai str. 56601 endoflagellar biosynthesis protein NP_712788.1 2592094 R 189518 CDS NP_712789.2 294828141 1151951 complement(2594221..2596161) 1 NC_004342.2 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2596161 flhB 1151951 flhB Leptospira interrogans serovar Lai str. 56601 flagellar biosynthesis protein FlhB NP_712789.2 2594221 R 189518 CDS NP_712790.1 24215309 1151952 complement(2596158..2596937) 1 NC_004342.2 flagellar biosynthetic protein 2596937 fliR 1151952 fliR Leptospira interrogans serovar Lai str. 56601 flagellar biosynthetic protein NP_712790.1 2596158 R 189518 CDS NP_712791.1 24215310 1151953 complement(2596944..2597207) 1 NC_004342.2 endoflagellar biosynthesis pathway protein 2597207 fliQ 1151953 fliQ Leptospira interrogans serovar Lai str. 56601 endoflagellar biosynthesis pathway protein NP_712791.1 2596944 R 189518 CDS NP_712792.2 294828142 1151954 complement(2597204..2597959) 1 NC_004342.2 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2597959 fliP 1151954 fliP Leptospira interrogans serovar Lai str. 56601 flagellar biosynthesis protein FliP NP_712792.2 2597204 R 189518 CDS NP_712793.1 24215312 1151955 complement(2598040..2598861) 1 NC_004342.2 endoflagellar biogenesis protein 2598861 1151955 LA_2612 Leptospira interrogans serovar Lai str. 56601 endoflagellar biogenesis protein NP_712793.1 2598040 R 189518 CDS NP_712794.1 24215313 1151956 complement(2598858..2599922) 1 NC_004342.2 endoflagellar motor switch protein 2599922 1151956 LA_2613 Leptospira interrogans serovar Lai str. 56601 endoflagellar motor switch protein NP_712794.1 2598858 R 189518 CDS NP_712796.1 24215315 1151958 complement(2600490..2600816) 1 NC_004342.2 hypothetical protein 2600816 1151958 LA_2615 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712796.1 2600490 R 189518 CDS NP_712797.2 294828143 1151959 complement(2601180..2603405) 1 NC_004342.2 sodium:alanine symporter/phosphatidylserine decarboxylase 2603405 alsT 1151959 alsT Leptospira interrogans serovar Lai str. 56601 sodium:alanine symporter/phosphatidylserine decarboxylase NP_712797.2 2601180 R 189518 CDS NP_712799.1 24215318 1151961 2603468..2604334 1 NC_004342.2 hypothetical protein 2604334 1151961 LA_2617 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712799.1 2603468 D 189518 CDS NP_712801.1 24215320 1151963 complement(2604683..2605879) 1 NC_004342.2 sterol desaturase 2605879 erg3 1151963 erg3 Leptospira interrogans serovar Lai str. 56601 sterol desaturase NP_712801.1 2604683 R 189518 CDS NP_712802.2 294828144 1151964 complement(2605886..2606671) 1 NC_004342.2 short-chain dehydrogenase 2606671 dltE 1151964 dltE Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_712802.2 2605886 R 189518 CDS NP_712804.1 24215323 1151966 2606858..2607514 1 NC_004342.2 glutathione transferase 2607514 gst 1151966 gst Leptospira interrogans serovar Lai str. 56601 glutathione transferase NP_712804.1 2606858 D 189518 CDS NP_712805.2 294828145 1151967 2607588..2607824 1 NC_004342.2 hypothetical protein 2607824 1151967 LA_2624 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712805.2 2607588 D 189518 CDS NP_712806.1 24215325 1151968 complement(2607832..2609787) 1 NC_004342.2 oligopeptidase A 2609787 dcp 1151968 dcp Leptospira interrogans serovar Lai str. 56601 oligopeptidase A NP_712806.1 2607832 R 189518 CDS NP_712807.2 294828146 1151969 2610634..2611245 1 NC_004342.2 hypothetical protein 2611245 1151969 LA_2626 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712807.2 2610634 D 189518 CDS NP_712808.1 24215327 1151970 2611471..2612649 1 NC_004342.2 MaoC family protein 2612649 1151970 LA_2627 Leptospira interrogans serovar Lai str. 56601 MaoC family protein NP_712808.1 2611471 D 189518 CDS NP_712809.1 24215328 1151971 complement(2612790..2614706) 1 NC_004342.2 hypothetical protein 2614706 1151971 LA_2628 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712809.1 2612790 R 189518 CDS NP_712810.1 24215329 1151972 2614956..2615984 1 NC_004342.2 alcohol dehydrogenase 2615984 1151972 LA_2629 Leptospira interrogans serovar Lai str. 56601 alcohol dehydrogenase NP_712810.1 2614956 D 189518 CDS NP_712812.1 24215331 1151974 complement(2616534..2616854) 1 NC_004342.2 ATP-dependent Clp protease adaptor protein ClpS 2616854 clpS 1151974 clpS Leptospira interrogans serovar Lai str. 56601 ATP-dependent Clp protease adaptor protein ClpS NP_712812.1 2616534 R 189518 CDS NP_712813.1 24215332 1151975 complement(2616973..2617935) 1 NC_004342.2 hypothetical protein 2617935 1151975 LA_2632 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712813.1 2616973 R 189518 CDS NP_712814.3 294828147 1151976 complement(2617943..2619181) 1 NC_004342.2 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2619181 metK 1151976 metK Leptospira interrogans serovar Lai str. 56601 S-adenosylmethionine synthetase NP_712814.3 2617943 R 189518 CDS NP_712815.1 24215334 1151977 2619274..2619672 1 NC_004342.2 ParB-like protein 2619672 1151977 LA_2634 Leptospira interrogans serovar Lai str. 56601 ParB-like protein NP_712815.1 2619274 D 189518 CDS NP_712818.1 24215337 1151980 2619904..2620722 1 NC_004342.2 hypothetical protein 2620722 lipL32 1151980 lipL32 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712818.1 2619904 D 189518 CDS NP_712820.1 24215339 1151982 2622169..2623929 1 NC_004342.2 acyl-CoA dehydrogenase 2623929 caiA 1151982 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_712820.1 2622169 D 189518 CDS NP_712821.1 24215340 1151983 2623997..2624623 1 NC_004342.2 hypothetical protein 2624623 1151983 LA_2640 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712821.1 2623997 D 189518 CDS YP_003573326.1 294828148 9006931 2624958..2625191 1 NC_004342.2 hypothetical protein 2625191 9006931 LA_2640a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573326.1 2624958 D 189518 CDS NP_712822.1 24215341 1151984 2625395..2627635 1 NC_004342.2 ferrichrome-iron receptor 2627635 1151984 LA_2641 Leptospira interrogans serovar Lai str. 56601 ferrichrome-iron receptor NP_712822.1 2625395 D 189518 CDS NP_712823.1 24215342 1151985 2627719..2627913 1 NC_004342.2 hypothetical protein 2627913 1151985 LA_2642 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712823.1 2627719 D 189518 CDS NP_712824.1 24215343 1151986 complement(2628186..2629022) 1 NC_004342.2 nucleoside-diphosphate-sugar epimerase 2629022 1151986 LA_2644 Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar epimerase NP_712824.1 2628186 R 189518 CDS NP_712825.2 294828149 1151987 2628987..2630324 1 NC_004342.2 guanylate cyclase 2630324 cyaA 1151987 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_712825.2 2628987 D 189518 CDS NP_712826.1 24215345 1151988 complement(2630515..2630997) 1 NC_004342.2 hypothetical protein 2630997 1151988 LA_2645 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712826.1 2630515 R 189518 CDS NP_712829.1 24215348 1151991 complement(2631802..2632146) 1 NC_004342.2 hypothetical protein 2632146 1151991 LA_2648 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712829.1 2631802 R 189518 CDS NP_712830.1 24215349 1151992 complement(2632436..2633986) 1 NC_004342.2 deoxyribodipyrimidine photolyase 2633986 1151992 LA_2649 Leptospira interrogans serovar Lai str. 56601 deoxyribodipyrimidine photolyase NP_712830.1 2632436 R 189518 CDS NP_712832.2 294828150 1151994 2635147..2635305 1 NC_004342.2 transposase 2635305 1151994 LA_2651 Leptospira interrogans serovar Lai str. 56601 transposase NP_712832.2 2635147 D 189518 CDS NP_712833.2 294828151 1151995 2635311..2636153 1 NC_004342.2 transposase 2636153 tra5 1151995 tra5 Leptospira interrogans serovar Lai str. 56601 transposase NP_712833.2 2635311 D 189518 CDS NP_712835.1 24215354 1151997 2638267..2638557 1 NC_004342.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 2638557 groES 1151997 groES Leptospira interrogans serovar Lai str. 56601 co-chaperonin GroES NP_712835.1 2638267 D 189518 CDS NP_712836.1 24215355 1151998 2638572..2640212 1 NC_004342.2 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 2640212 groEL 1151998 groEL Leptospira interrogans serovar Lai str. 56601 molecular chaperone GroEL NP_712836.1 2638572 D 189518 CDS NP_712837.1 24215356 1151999 2640316..2640987 1 NC_004342.2 hypothetical protein 2640987 1151999 LA_2656 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712837.1 2640316 D 189518 CDS NP_712840.2 294828152 1152002 2642094..2643326 1 NC_004342.2 biotin carboxylase 2643326 1152002 LA_2659 Leptospira interrogans serovar Lai str. 56601 biotin carboxylase NP_712840.2 2642094 D 189518 CDS NP_712841.1 24215360 1152003 2643313..2643951 1 NC_004342.2 SAM-dependent methyltransferase 2643951 1152003 LA_2660 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_712841.1 2643313 D 189518 CDS NP_712842.1 24215361 1152004 2643927..2644814 1 NC_004342.2 methylase/methyltransferase 2644814 1152004 LA_2661 Leptospira interrogans serovar Lai str. 56601 methylase/methyltransferase NP_712842.1 2643927 D 189518 CDS NP_712843.1 24215362 1152005 2644818..2647067 1 NC_004342.2 ribonuclease BN 2647067 1152005 LA_2662 Leptospira interrogans serovar Lai str. 56601 ribonuclease BN NP_712843.1 2644818 D 189518 CDS NP_712844.1 24215363 1152006 complement(2647665..2648138) 1 NC_004342.2 cell envelope rod binding protein 2648138 1152006 LA_2663 Leptospira interrogans serovar Lai str. 56601 cell envelope rod binding protein NP_712844.1 2647665 R 189518 CDS NP_712845.1 24215364 1152007 complement(2648135..2649235) 1 NC_004342.2 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 2649235 flgI 1152007 flgI Leptospira interrogans serovar Lai str. 56601 flagellar basal body P-ring biosynthesis protein FlgA NP_712845.1 2648135 R 189518 CDS NP_712846.1 24215365 1152008 complement(2649232..2650233) 1 NC_004342.2 flagellar L-ring protein precursor 2650233 1152008 LA_2665 Leptospira interrogans serovar Lai str. 56601 flagellar L-ring protein precursor NP_712846.1 2649232 R 189518 CDS NP_712847.1 24215366 1152009 complement(2650230..2651120) 1 NC_004342.2 endoflagellar basal body P-ring biosynthesis protein 2651120 1152009 LA_2666 Leptospira interrogans serovar Lai str. 56601 endoflagellar basal body P-ring biosynthesis protein NP_712847.1 2650230 R 189518 CDS NP_712848.2 294828153 1152010 complement(2651139..2651933) 1 NC_004342.2 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 2651933 flgG 1152010 flgG Leptospira interrogans serovar Lai str. 56601 flagellar basal body rod protein FlgG NP_712848.2 2651139 R 189518 CDS NP_712849.1 24215368 1152011 complement(2652662..2653813) 1 NC_004342.2 methyltransferase DNA modification enzyme 2653813 1152011 LA_2668 Leptospira interrogans serovar Lai str. 56601 methyltransferase DNA modification enzyme NP_712849.1 2652662 R 189518 CDS NP_712852.1 24215371 1152014 complement(2655801..2656067) 1 NC_004342.2 hypothetical protein 2656067 1152014 LA_2671 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712852.1 2655801 R 189518 CDS NP_712853.1 24215372 1152015 2656639..2657655 1 NC_004342.2 hypothetical protein 2657655 1152015 LA_2672 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712853.1 2656639 D 189518 CDS NP_712855.1 24215374 1152017 2658763..2659944 1 NC_004342.2 metal-dependent amidase/aminoacylase/carboxypeptidase 2659944 abgB 1152017 abgB Leptospira interrogans serovar Lai str. 56601 metal-dependent amidase/aminoacylase/carboxypeptidase NP_712855.1 2658763 D 189518 CDS NP_712857.1 24215376 1152019 complement(2660692..2662980) 1 NC_004342.2 hypothetical protein 2662980 1152019 LA_2676 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712857.1 2660692 R 189518 CDS NP_712859.2 294828154 1152021 complement(2663847..2664068) 1 NC_004342.2 hypothetical protein 2664068 1152021 LA_2678 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712859.2 2663847 R 189518 CDS NP_712860.2 294828155 1152022 2664359..2664517 1 NC_004342.2 transposase 2664517 1152022 LA_2679 Leptospira interrogans serovar Lai str. 56601 transposase NP_712860.2 2664359 D 189518 CDS NP_712861.2 294828156 1152023 2664523..2665365 1 NC_004342.2 transposase 2665365 tra5 1152023 tra5 Leptospira interrogans serovar Lai str. 56601 transposase NP_712861.2 2664523 D 189518 CDS NP_712862.1 24215381 1152024 complement(2665393..2666922) 1 NC_004342.2 hypothetical protein 2666922 1152024 LA_2681 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712862.1 2665393 R 189518 CDS NP_712863.2 294828157 1152025 complement(2666961..2668340) 1 NC_004342.2 hypothetical protein 2668340 1152025 LA_2682 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712863.2 2666961 R 189518 CDS NP_712864.1 24215383 1152026 complement(2668796..2669347) 1 NC_004342.2 hypothetical protein 2669347 1152026 LA_2683 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712864.1 2668796 R 189518 CDS NP_712865.1 24215384 1152027 complement(2669433..2669912) 1 NC_004342.2 hypothetical protein 2669912 1152027 LA_2684 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712865.1 2669433 R 189518 CDS NP_712866.2 294828158 1152028 complement(2669979..2670506) 1 NC_004342.2 P-loop domain-containing protein 2670506 1152028 LA_2685 Leptospira interrogans serovar Lai str. 56601 P-loop domain-containing protein NP_712866.2 2669979 R 189518 CDS NP_712867.1 24215386 1152029 complement(2670551..2670892) 1 NC_004342.2 hypothetical protein 2670892 1152029 LA_2686 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712867.1 2670551 R 189518 CDS NP_712868.1 24215387 1152030 complement(2671244..2672533) 1 NC_004342.2 aminopeptidase 2672533 pepP 1152030 pepP Leptospira interrogans serovar Lai str. 56601 aminopeptidase NP_712868.1 2671244 R 189518 CDS NP_712869.2 294828159 1152031 complement(2672530..2673561) 1 NC_004342.2 lipopolysaccharide heptosyltransferase II 2673561 rfaF 1152031 rfaF Leptospira interrogans serovar Lai str. 56601 lipopolysaccharide heptosyltransferase II NP_712869.2 2672530 R 189518 CDS NP_712870.1 24215389 1152032 complement(2673575..2674732) 1 NC_004342.2 acetyl-CoA acetyltransferase 2674732 1152032 LA_2689 Leptospira interrogans serovar Lai str. 56601 acetyl-CoA acetyltransferase NP_712870.1 2673575 R 189518 CDS NP_712871.2 294828160 1152033 2674840..2675307 1 NC_004342.2 bacterioferritin 2675307 bfr 1152033 bfr Leptospira interrogans serovar Lai str. 56601 bacterioferritin NP_712871.2 2674840 D 189518 CDS NP_712872.1 24215391 1152034 2675304..2676554 1 NC_004342.2 N6-adenine-specific DNA methylase 2676554 1152034 LA_2691 Leptospira interrogans serovar Lai str. 56601 N6-adenine-specific DNA methylase NP_712872.1 2675304 D 189518 CDS NP_712873.1 24215392 1152035 2676570..2677682 1 NC_004342.2 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 2677682 1152035 LA_2692 Leptospira interrogans serovar Lai str. 56601 acetylglutamate kinase NP_712873.1 2676570 D 189518 CDS NP_712874.1 24215393 1152036 complement(2677720..2678124) 1 NC_004342.2 hypothetical protein 2678124 1152036 LA_2693 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712874.1 2677720 R 189518 CDS NP_712878.1 24215397 1152040 2679098..2679442 1 NC_004342.2 hypothetical protein 2679442 1152040 LA_2697 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712878.1 2679098 D 189518 CDS NP_712879.1 24215398 1152041 complement(2679419..2680105) 1 NC_004342.2 hypothetical protein 2680105 1152041 LA_2698 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712879.1 2679419 R 189518 CDS NP_712880.1 24215399 1152042 complement(2680118..2681242) 1 NC_004342.2 D-alanine--D-alanine ligase 2681242 1152042 LA_2699 Leptospira interrogans serovar Lai str. 56601 D-alanine--D-alanine ligase NP_712880.1 2680118 R 189518 CDS NP_712881.1 24215400 1152043 complement(2681235..2682485) 1 NC_004342.2 L-lysine 2,3-aminomutase 2682485 kamA 1152043 kamA Leptospira interrogans serovar Lai str. 56601 L-lysine 2,3-aminomutase NP_712881.1 2681235 R 189518 CDS NP_712883.1 24215402 1152045 2682569..2683243 1 NC_004342.2 phosphoglycolate phosphatase 2683243 1152045 LA_2702 Leptospira interrogans serovar Lai str. 56601 phosphoglycolate phosphatase NP_712883.1 2682569 D 189518 CDS NP_712884.1 24215403 1152046 2683287..2684096 1 NC_004342.2 hypothetical protein 2684096 1152046 LA_2703 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712884.1 2683287 D 189518 CDS NP_712885.1 24215404 1152047 2684210..2685439 1 NC_004342.2 two-component response regulator 2685439 1152047 LA_2704 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_712885.1 2684210 D 189518 CDS NP_712886.2 294828161 1152048 complement(2685423..2685791) 1 NC_004342.2 hypothetical protein 2685791 1152048 LA_2705 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712886.2 2685423 R 189518 CDS NP_712887.1 24215406 1152049 complement(2686651..2687754) 1 NC_004342.2 thiamine biosynthesis enzyme 2687754 thiH 1152049 thiH Leptospira interrogans serovar Lai str. 56601 thiamine biosynthesis enzyme NP_712887.1 2686651 R 189518 CDS NP_712890.1 24215409 1152052 complement(2689226..2690281) 1 NC_004342.2 dolichyl-phosphate mannose synthase 2690281 1152052 LA_2709 Leptospira interrogans serovar Lai str. 56601 dolichyl-phosphate mannose synthase NP_712890.1 2689226 R 189518 CDS NP_712892.1 24215411 1152054 complement(2690508..2692442) 1 NC_004342.2 hypothetical protein 2692442 1152054 LA_2711 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712892.1 2690508 R 189518 CDS NP_712893.2 294828162 1152055 2692958..2695048 1 NC_004342.2 Fe-S oxidoreductase 2695048 1152055 LA_2712 Leptospira interrogans serovar Lai str. 56601 Fe-S oxidoreductase NP_712893.2 2692958 D 189518 CDS NP_712894.2 294828163 1152056 complement(2696208..2696567) 1 NC_004342.2 hypothetical protein 2696567 1152056 LA_2713 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712894.2 2696208 R 189518 CDS NP_712896.2 294828164 1152058 complement(2697115..2698026) 1 NC_004342.2 two component system sensor histidine kinase 2698026 1152058 LA_2715 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase NP_712896.2 2697115 R 189518 CDS NP_712898.2 294828165 1152060 complement(2698655..2699764) 1 NC_004342.2 histidine kinase sensor protein 2699764 1152060 LA_2717 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_712898.2 2698655 R 189518 CDS NP_712899.1 24215418 1152061 complement(2700301..2701446) 1 NC_004342.2 cytoplasmic membrane protein 2701446 1152061 LA_2718 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_712899.1 2700301 R 189518 CDS NP_712900.1 24215419 1152062 complement(2701443..2703749) 1 NC_004342.2 hypothetical protein 2703749 1152062 LA_2719 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712900.1 2701443 R 189518 CDS NP_712901.1 24215420 1152063 complement(2703831..2704007) 1 NC_004342.2 hypothetical protein 2704007 1152063 LA_2720 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712901.1 2703831 R 189518 CDS NP_712903.1 24215422 1152065 complement(2704683..2705105) 1 NC_004342.2 hypothetical protein 2705105 1152065 LA_2722 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712903.1 2704683 R 189518 CDS NP_712904.2 294828166 1152066 complement(2705215..2706174) 1 NC_004342.2 metal-dependent hydrolase 2706174 1152066 LA_2723 Leptospira interrogans serovar Lai str. 56601 metal-dependent hydrolase NP_712904.2 2705215 R 189518 CDS NP_712905.1 24215424 1152067 2706361..2706630 1 NC_004342.2 hypothetical protein 2706630 1152067 LA_2724 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712905.1 2706361 D 189518 CDS NP_712907.1 24215426 1152069 complement(2707068..2708015) 1 NC_004342.2 dioxygenase 2708015 1152069 LA_2727 Leptospira interrogans serovar Lai str. 56601 dioxygenase NP_712907.1 2707068 R 189518 CDS NP_712908.2 294828167 1152070 2708007..2708366 1 NC_004342.2 hypothetical protein 2708366 1152070 LA_2726 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712908.2 2708007 D 189518 CDS NP_712909.1 24215428 1152071 2708699..2709118 1 NC_004342.2 transcriptional regulator 2709118 1152071 LA_2728 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_712909.1 2708699 D 189518 CDS NP_712910.2 294828168 1152072 complement(2709569..2710738) 1 NC_004342.2 ISlin1 transposase 2710738 1152072 LA_2729 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_712910.2 2709569 R 189518 CDS NP_712911.2 294828169 1152073 complement(2711742..2712254) 1 NC_004342.2 hypothetical protein 2712254 1152073 LA_2730 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712911.2 2711742 R 189518 CDS NP_712912.1 24215431 1152074 complement(2712438..2712815) 1 NC_004342.2 hypothetical protein 2712815 1152074 LA_2731 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712912.1 2712438 R 189518 CDS NP_712914.1 24215433 1152076 complement(2713950..2715722) 1 NC_004342.2 peptide chain release factor 3 2715722 prfC 1152076 prfC Leptospira interrogans serovar Lai str. 56601 peptide chain release factor 3 NP_712914.1 2713950 R 189518 CDS NP_712916.2 294828170 1152078 complement(2716274..2716774) 1 NC_004342.2 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 2716774 1152078 LA_2735 Leptospira interrogans serovar Lai str. 56601 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit NP_712916.2 2716274 R 189518 CDS NP_712917.1 24215436 1152079 complement(2716771..2718234) 1 NC_004342.2 acetyl-CoA carboxylase biotin carboxylase subunit 2718234 1152079 LA_2736 Leptospira interrogans serovar Lai str. 56601 acetyl-CoA carboxylase biotin carboxylase subunit NP_712917.1 2716771 R 189518 CDS NP_712918.1 24215437 1152080 complement(2718231..2719028) 1 NC_004342.2 acyltransferase 2719028 1152080 LA_2737 Leptospira interrogans serovar Lai str. 56601 acyltransferase NP_712918.1 2718231 R 189518 CDS NP_712919.1 24215438 1152081 complement(2719262..2720371) 1 NC_004342.2 hypothetical protein 2720371 1152081 LA_2738 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712919.1 2719262 R 189518 CDS NP_712920.1 24215439 1152082 2720516..2721397 1 NC_004342.2 hypothetical protein 2721397 1152082 LA_2739 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712920.1 2720516 D 189518 CDS NP_712921.1 24215440 1152083 2721568..2722191 1 NC_004342.2 pseudouridylate synthase 2722191 truA 1152083 truA Leptospira interrogans serovar Lai str. 56601 pseudouridylate synthase NP_712921.1 2721568 D 189518 CDS NP_712922.1 24215441 1152084 2722194..2723012 1 NC_004342.2 hypothetical protein 2723012 1152084 LA_2741 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712922.1 2722194 D 189518 CDS NP_712923.2 294828171 1152085 2723057..2724298 1 NC_004342.2 hypothetical protein 2724298 1152085 LA_2742 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712923.2 2723057 D 189518 CDS NP_712928.2 294828172 1152090 2726126..2727955 1 NC_004342.2 hypothetical protein 2727955 1152090 LA_2746 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712928.2 2726126 D 189518 CDS NP_712929.1 24215448 1152091 2727984..2728988 1 NC_004342.2 sulfate ABC transporter substrate-binding protein 2728988 sbp 1152091 sbp Leptospira interrogans serovar Lai str. 56601 sulfate ABC transporter substrate-binding protein NP_712929.1 2727984 D 189518 CDS NP_712930.1 24215449 1152092 complement(2730171..2730581) 1 NC_004342.2 6-pyruvoyl tetrahydrobiopterin synthase 2730581 1152092 LA_2749 Leptospira interrogans serovar Lai str. 56601 6-pyruvoyl tetrahydrobiopterin synthase NP_712930.1 2730171 R 189518 CDS NP_712932.1 24215451 1152094 2730709..2730936 1 NC_004342.2 hypothetical protein 2730936 1152094 LA_2751 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712932.1 2730709 D 189518 CDS YP_003573327.1 294828173 9006932 2731235..2731978 1 NC_004342.2 hypothetical protein 2731978 9006932 LA_2751a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573327.1 2731235 D 189518 CDS NP_712934.1 24215453 1152096 complement(2732468..2733250) 1 NC_004342.2 hypothetical protein 2733250 1152096 LA_2753 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712934.1 2732468 R 189518 CDS NP_712935.2 294828174 1152097 complement(2733686..2735191) 1 NC_004342.2 rod shape-determining protein 2735191 rodA 1152097 rodA Leptospira interrogans serovar Lai str. 56601 rod shape-determining protein NP_712935.2 2733686 R 189518 CDS NP_712936.1 24215455 1152098 complement(2735178..2737121) 1 NC_004342.2 transpeptidase/penicillin binding protein 2737121 ftsI 1152098 ftsI Leptospira interrogans serovar Lai str. 56601 transpeptidase/penicillin binding protein NP_712936.1 2735178 R 189518 CDS NP_712937.1 24215456 1152099 complement(2737123..2737635) 1 NC_004342.2 cell shape-determining protein 2737635 1152099 LA_2756 Leptospira interrogans serovar Lai str. 56601 cell shape-determining protein NP_712937.1 2737123 R 189518 CDS NP_712938.2 294828175 1152100 complement(2737632..2738765) 1 NC_004342.2 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2738765 mreC 1152100 mreC Leptospira interrogans serovar Lai str. 56601 rod shape-determining protein MreC NP_712938.2 2737632 R 189518 CDS NP_712940.1 24215459 1152102 complement(2738803..2739825) 1 NC_004342.2 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 2739825 mreB 1152102 mreB Leptospira interrogans serovar Lai str. 56601 rod shape-determining protein MreB NP_712940.1 2738803 R 189518 CDS NP_712942.1 24215461 1152104 2740017..2741579 1 NC_004342.2 exopolyphosphatase 2741579 ppx 1152104 ppx Leptospira interrogans serovar Lai str. 56601 exopolyphosphatase NP_712942.1 2740017 D 189518 CDS NP_712943.1 24215462 1152105 2742032..2742373 1 NC_004342.2 hypothetical protein 2742373 1152105 LA_2762 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712943.1 2742032 D 189518 CDS NP_712945.2 294828176 1152107 2745054..2746292 1 NC_004342.2 hypothetical protein 2746292 1152107 LA_2764 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712945.2 2745054 D 189518 CDS NP_712946.1 24215465 1152108 complement(2746703..2746924) 1 NC_004342.2 hypothetical protein 2746924 1152108 LA_2765 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712946.1 2746703 R 189518 CDS NP_712948.1 24215467 1152110 2747624..2748313 1 NC_004342.2 hypothetical protein 2748313 1152110 LA_2767 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712948.1 2747624 D 189518 CDS NP_712951.1 24215470 1152113 complement(2748912..2750048) 1 NC_004342.2 hypothetical protein 2750048 1152113 LA_2770 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712951.1 2748912 R 189518 CDS NP_712952.1 24215471 1152114 complement(2750246..2751670) 1 NC_004342.2 MBOAT family D-alaninealginate export/acetyltransferase membrane protein 2751670 dltB 1152114 dltB Leptospira interrogans serovar Lai str. 56601 MBOAT family D-alaninealginate export/acetyltransferase membrane protein NP_712952.1 2750246 R 189518 CDS NP_712953.2 294828177 1152115 complement(2751682..2753838) 1 NC_004342.2 cGMP-specific phosphodiesterase 2753838 1152115 LA_2772 Leptospira interrogans serovar Lai str. 56601 cGMP-specific phosphodiesterase NP_712953.2 2751682 R 189518 CDS NP_712954.2 294828178 1152116 complement(2753842..2757294) 1 NC_004342.2 hypothetical protein 2757294 1152116 LA_2773 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712954.2 2753842 R 189518 CDS NP_712955.2 294828179 1152117 complement(2757325..2757606) 1 NC_004342.2 hypothetical protein 2757606 1152117 LA_2774 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712955.2 2757325 R 189518 CDS NP_712956.1 24215475 1152118 complement(2757689..2758072) 1 NC_004342.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit epsilon 2758072 atpC 1152118 atpC Leptospira interrogans serovar Lai str. 56601 ATP synthase F0F1 subunit epsilon NP_712956.1 2757689 R 189518 CDS NP_712957.2 294828180 1152119 complement(2758078..2759481) 1 NC_004342.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 2759481 atpD 1152119 atpD Leptospira interrogans serovar Lai str. 56601 ATP synthase F0F1 subunit beta NP_712957.2 2758078 R 189518 CDS NP_712958.2 229020021 1152120 complement(2759499..2760359) 1 NC_004342.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 2760359 atpG 1152120 atpG Leptospira interrogans serovar Lai str. 56601 ATP synthase F0F1 subunit gamma NP_712958.2 2759499 R 189518 CDS NP_712960.2 161484948 1152122 complement(2760374..2761885) 1 NC_004342.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 2761885 atpA 1152122 atpA Leptospira interrogans serovar Lai str. 56601 ATP synthase F0F1 subunit alpha NP_712960.2 2760374 R 189518 CDS NP_712961.1 24215480 1152123 complement(2761875..2762435) 1 NC_004342.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 2762435 atpH 1152123 atpH Leptospira interrogans serovar Lai str. 56601 ATP synthase F0F1 subunit delta NP_712961.1 2761875 R 189518 CDS NP_712962.1 24215481 1152124 complement(2762440..2762961) 1 NC_004342.2 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel; ATP synthase F0F1 subunit B 2762961 atpF 1152124 atpF Leptospira interrogans serovar Lai str. 56601 ATP synthase F0F1 subunit B NP_712962.1 2762440 R 189518 CDS NP_712963.2 294828181 1152125 complement(2762965..2763264) 1 NC_004342.2 ATP synthase subunit C 2763264 atpE 1152125 atpE Leptospira interrogans serovar Lai str. 56601 ATP synthase subunit C NP_712963.2 2762965 R 189518 CDS NP_712964.2 294828182 1152126 complement(2763300..2764286) 1 NC_004342.2 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 2764286 atpB 1152126 atpB Leptospira interrogans serovar Lai str. 56601 ATP synthase F0F1 subunit A NP_712964.2 2763300 R 189518 CDS YP_003573328.1 294828183 9006933 complement(2764454..2764783) 1 NC_004342.2 hypothetical protein 2764783 9006933 LA_2783a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573328.1 2764454 R 189518 CDS NP_712968.1 24215487 1152130 complement(2765887..2766186) 1 NC_004342.2 hypothetical protein 2766186 1152130 LA_2787 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712968.1 2765887 R 189518 CDS NP_712969.1 24215488 1152131 complement(2766156..2767157) 1 NC_004342.2 signal peptidase I 2767157 lepB 1152131 lepB Leptospira interrogans serovar Lai str. 56601 signal peptidase I NP_712969.1 2766156 R 189518 CDS NP_712970.2 294828184 1152132 2767244..2768047 1 NC_004342.2 hypothetical protein 2768047 1152132 LA_2789 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712970.2 2767244 D 189518 CDS NP_712971.1 24215490 1152133 2768050..2768601 1 NC_004342.2 transcriptional regulator 2768601 1152133 LA_2790 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_712971.1 2768050 D 189518 CDS NP_712972.2 294828185 1152134 complement(2769472..2771463) 1 NC_004342.2 hypothetical protein 2771463 1152134 LA_2791 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712972.2 2769472 R 189518 CDS NP_712974.1 24215493 1152136 2772526..2773545 1 NC_004342.2 magnesium and cobalt transport protein CorA 2773545 corA 1152136 corA Leptospira interrogans serovar Lai str. 56601 magnesium and cobalt transport protein CorA NP_712974.1 2772526 D 189518 CDS NP_712977.2 294828186 1152139 2774723..2776177 1 NC_004342.2 hypothetical protein 2776177 1152139 LA_2796 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712977.2 2774723 D 189518 CDS NP_712978.1 24215497 1152140 2776192..2776920 1 NC_004342.2 hypothetical protein 2776920 1152140 LA_2797 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712978.1 2776192 D 189518 CDS NP_712979.1 24215498 1152141 2777678..2778118 1 NC_004342.2 hypothetical protein 2778118 1152141 LA_2798 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712979.1 2777678 D 189518 CDS NP_712981.2 294828187 1152143 complement(2778772..2779878) 1 NC_004342.2 hypothetical protein 2779878 1152143 LA_2800 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712981.2 2778772 R 189518 CDS NP_712982.1 24215501 1152144 2780261..2781826 1 NC_004342.2 hypothetical protein 2781826 1152144 LA_2801 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712982.1 2780261 D 189518 CDS NP_712984.1 24215503 1152146 complement(2781999..2782853) 1 NC_004342.2 TPR-repeat-containing protein 2782853 1152146 LA_2803 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_712984.1 2781999 R 189518 CDS NP_712986.1 24215505 1152148 complement(2783359..2786934) 1 NC_004342.2 histidine kinase sensor protein 2786934 1152148 LA_2805 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_712986.1 2783359 R 189518 CDS NP_712989.1 24215508 1152151 complement(2788935..2790350) 1 NC_004342.2 ABC transporter permease 2790350 sufB 1152151 sufB Leptospira interrogans serovar Lai str. 56601 ABC transporter permease NP_712989.1 2788935 R 189518 CDS NP_712990.1 24215509 1152152 complement(2790843..2791424) 1 NC_004342.2 peroxiredoxin 2791424 ahpC 1152152 ahpC Leptospira interrogans serovar Lai str. 56601 peroxiredoxin NP_712990.1 2790843 R 189518 CDS NP_712992.1 24215511 1152154 complement(2792388..2793356) 1 NC_004342.2 hypothetical protein 2793356 1152154 LA_2811 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712992.1 2792388 R 189518 CDS NP_712993.1 24215512 1152155 2793385..2793564 1 NC_004342.2 hypothetical protein 2793564 1152155 LA_2812 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712993.1 2793385 D 189518 CDS NP_712994.2 294828188 1152156 complement(2793605..2795278) 1 NC_004342.2 methyl-accepting chemotaxis protein 2795278 1152156 LA_2813 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_712994.2 2793605 R 189518 CDS NP_712996.1 24215515 1152158 complement(2797143..2797328) 1 NC_004342.2 hypothetical protein 2797328 1152158 LA_2816 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712996.1 2797143 R 189518 CDS NP_712997.1 24215516 1152159 2797301..2797726 1 NC_004342.2 hypothetical protein 2797726 1152159 LA_2815 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712997.1 2797301 D 189518 CDS NP_712998.2 294828189 1152160 2797723..2798295 1 NC_004342.2 hypothetical protein 2798295 1152160 LA_2817 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712998.2 2797723 D 189518 CDS NP_712999.1 24215518 1152161 2798292..2799356 1 NC_004342.2 hypothetical protein 2799356 1152161 LA_2818 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_712999.1 2798292 D 189518 CDS NP_713001.2 294828190 1152163 complement(2800489..2802498) 1 NC_004342.2 hypothetical protein 2802498 1152163 LA_2820 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713001.2 2800489 R 189518 CDS NP_713002.1 24215521 1152164 2802628..2803032 1 NC_004342.2 hypothetical protein 2803032 1152164 LA_2821 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713002.1 2802628 D 189518 CDS NP_713004.2 294828191 1152166 2805672..2806721 1 NC_004342.2 hypothetical protein 2806721 1152166 LA_2823 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713004.2 2805672 D 189518 CDS NP_713005.1 24215524 1152167 complement(2806955..2807353) 1 NC_004342.2 hypothetical protein 2807353 1152167 LA_2824 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713005.1 2806955 R 189518 CDS NP_713007.1 24215526 1152169 complement(2808140..2808907) 1 NC_004342.2 hypothetical protein 2808907 1152169 LA_2826 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713007.1 2808140 R 189518 CDS NP_713008.1 24215527 1152170 complement(2809791..2811005) 1 NC_004342.2 signal transduction protein 2811005 1152170 LA_2827 Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_713008.1 2809791 R 189518 CDS NP_713009.2 294828192 1152171 complement(2811017..2812501) 1 NC_004342.2 two component system sensor histidine kinase\response regulator 2812501 1152171 LA_2828 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase\response regulator NP_713009.2 2811017 R 189518 CDS NP_713010.1 24215529 1152172 complement(2812494..2812952) 1 NC_004342.2 two-component system signal receiver 2812952 1152172 LA_2829 Leptospira interrogans serovar Lai str. 56601 two-component system signal receiver NP_713010.1 2812494 R 189518 CDS NP_713011.1 24215530 1152173 complement(2812956..2814083) 1 NC_004342.2 histidine kinase sensor protein 2814083 1152173 LA_2830 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_713011.1 2812956 R 189518 CDS NP_713012.1 24215531 1152174 complement(2814214..2815629) 1 NC_004342.2 histidine kinase sensor protein 2815629 1152174 LA_2831 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_713012.1 2814214 R 189518 CDS NP_713013.1 24215532 1152175 complement(2815697..2817988) 1 NC_004342.2 alpha-beta hydrolase family esterase 2817988 rssA 1152175 rssA Leptospira interrogans serovar Lai str. 56601 alpha-beta hydrolase family esterase NP_713013.1 2815697 R 189518 CDS NP_713015.1 24215534 1152177 complement(2818475..2819746) 1 NC_004342.2 guanylate cyclase 2819746 cyaA 1152177 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_713015.1 2818475 R 189518 CDS NP_713016.1 24215535 1152178 complement(2819749..2820153) 1 NC_004342.2 hypothetical protein 2820153 1152178 LA_2835 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713016.1 2819749 R 189518 CDS NP_713017.1 24215536 1152179 complement(2820150..2820617) 1 NC_004342.2 hypothetical protein 2820617 1152179 LA_2836 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713017.1 2820150 R 189518 CDS NP_713021.1 24215540 1152183 2821421..2822356 1 NC_004342.2 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 2822356 argF 1152183 argF Leptospira interrogans serovar Lai str. 56601 ornithine carbamoyltransferase NP_713021.1 2821421 D 189518 CDS NP_713022.2 294828193 1152184 2822496..2823488 1 NC_004342.2 citrate lyase 2823488 citE 1152184 citE Leptospira interrogans serovar Lai str. 56601 citrate lyase NP_713022.2 2822496 D 189518 CDS NP_713024.1 24215543 1152186 complement(2824228..2824569) 1 NC_004342.2 PemK-like protein 2824569 1152186 LA_2843 Leptospira interrogans serovar Lai str. 56601 PemK-like protein NP_713024.1 2824228 R 189518 CDS NP_713025.1 24215544 1152187 complement(2824556..2824804) 1 NC_004342.2 transcriptional regulator 2824804 1152187 LA_2844 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_713025.1 2824556 R 189518 CDS NP_713026.1 24215545 1152188 complement(2825621..2825917) 1 NC_004342.2 transcriptional regulator 2825917 1152188 LA_2845 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_713026.1 2825621 R 189518 CDS YP_003573330.1 294828194 9006935 2826071..2826331 1 NC_004342.2 hypothetical protein 2826331 9006935 LA_2845a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573330.1 2826071 D 189518 CDS NP_713028.1 24215547 1152190 complement(2827172..2829154) 1 NC_004342.2 response regulator with HD-GYP domain 2829154 1152190 LA_2847 Leptospira interrogans serovar Lai str. 56601 response regulator with HD-GYP domain NP_713028.1 2827172 R 189518 CDS NP_713029.1 24215548 1152191 complement(2829389..2830783) 1 NC_004342.2 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 2830783 flgE 1152191 flgE Leptospira interrogans serovar Lai str. 56601 flagellar hook protein FlgE NP_713029.1 2829389 R 189518 CDS NP_713030.1 24215549 1152192 complement(2830811..2831605) 1 NC_004342.2 flagellar hook assembly scaffolding protein 2831605 1152192 LA_2849 Leptospira interrogans serovar Lai str. 56601 flagellar hook assembly scaffolding protein NP_713030.1 2830811 R 189518 CDS NP_713031.1 24215550 1152193 complement(2831620..2833185) 1 NC_004342.2 flagellar protein 2833185 1152193 LA_2850 Leptospira interrogans serovar Lai str. 56601 flagellar protein NP_713031.1 2831620 R 189518 CDS NP_713035.1 24215554 1152197 complement(2835726..2836325) 1 NC_004342.2 hypothetical protein 2836325 1152197 LA_2854 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713035.1 2835726 R 189518 CDS NP_713038.2 294828195 1152200 2837390..2838397 1 NC_004342.2 MhpC-like protein 2838397 1152200 LA_2857 Leptospira interrogans serovar Lai str. 56601 MhpC-like protein NP_713038.2 2837390 D 189518 CDS NP_713039.2 294828196 1152201 2839252..2840421 1 NC_004342.2 ISlin1 transposase 2840421 1152201 LA_2858 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713039.2 2839252 D 189518 CDS NP_713040.1 24215559 1152202 complement(2840541..2841062) 1 NC_004342.2 hypothetical protein 2841062 1152202 LA_2859 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713040.1 2840541 R 189518 CDS NP_713041.1 24215560 1152203 complement(2841114..2842250) 1 NC_004342.2 carbon-nitrogen hydrolase-like protein 2842250 1152203 LA_2860 Leptospira interrogans serovar Lai str. 56601 carbon-nitrogen hydrolase-like protein NP_713041.1 2841114 R 189518 CDS NP_713043.1 24215562 1152205 complement(2843142..2844008) 1 NC_004342.2 cytoplasmic membrane protein 2844008 1152205 LA_2862 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713043.1 2843142 R 189518 CDS NP_713044.1 24215563 1152206 complement(2844005..2844538) 1 NC_004342.2 rhodanese-like thiosulfate sulfurtransferase 2844538 1152206 LA_2863 Leptospira interrogans serovar Lai str. 56601 rhodanese-like thiosulfate sulfurtransferase NP_713044.1 2844005 R 189518 CDS NP_713046.2 294828197 1152208 2846154..2847017 1 NC_004342.2 hypothetical protein 2847017 1152208 LA_2865 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713046.2 2846154 D 189518 CDS NP_713047.1 24215566 1152209 complement(2847249..2847713) 1 NC_004342.2 hypothetical protein 2847713 1152209 LA_2866 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713047.1 2847249 R 189518 CDS NP_713048.1 24215567 1152210 complement(2847918..2848985) 1 NC_004342.2 cytoplasmic membrane protein 2848985 1152210 LA_2867 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713048.1 2847918 R 189518 CDS NP_713049.1 24215568 1152211 2849042..2850136 1 NC_004342.2 translation initiation factor 2B 2850136 1152211 LA_2868 Leptospira interrogans serovar Lai str. 56601 translation initiation factor 2B NP_713049.1 2849042 D 189518 CDS NP_713051.2 294828198 1152213 2850953..2851213 1 NC_004342.2 hypothetical protein 2851213 1152213 LA_2870 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713051.2 2850953 D 189518 CDS NP_713052.1 24215571 1152214 complement(2851295..2852794) 1 NC_004342.2 polymerase 2852794 1152214 LA_2871 Leptospira interrogans serovar Lai str. 56601 polymerase NP_713052.1 2851295 R 189518 CDS NP_713053.2 294828199 1152215 complement(2853088..2854134) 1 NC_004342.2 hypothetical protein 2854134 1152215 LA_2872 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713053.2 2853088 R 189518 CDS NP_713054.2 294828200 1152216 complement(2854235..2855368) 1 NC_004342.2 hypothetical protein 2855368 1152216 LA_2873 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713054.2 2854235 R 189518 CDS NP_713056.1 24215575 1152218 2856269..2856922 1 NC_004342.2 hypothetical protein 2856922 1152218 LA_2874 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713056.1 2856269 D 189518 CDS NP_713057.2 294828201 1152219 complement(2856995..2857501) 1 NC_004342.2 hypothetical protein 2857501 1152219 LA_2876 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713057.2 2856995 R 189518 CDS NP_713058.1 24215577 1152220 complement(2857498..2858652) 1 NC_004342.2 hypothetical protein 2858652 1152220 LA_2877 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713058.1 2857498 R 189518 CDS NP_713059.1 24215578 1152221 2858712..2859455 1 NC_004342.2 SAM-dependent methyltransferase 2859455 1152221 LA_2878 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_713059.1 2858712 D 189518 CDS NP_713060.2 294828202 1152222 2859561..2859869 1 NC_004342.2 nucleotidyltransferase 2859869 1152222 LA_2879 Leptospira interrogans serovar Lai str. 56601 nucleotidyltransferase NP_713060.2 2859561 D 189518 CDS NP_713061.1 24215580 1152223 2859859..2860248 1 NC_004342.2 HEPN domain-containing protein 2860248 1152223 LA_2880 Leptospira interrogans serovar Lai str. 56601 HEPN domain-containing protein NP_713061.1 2859859 D 189518 CDS NP_713062.1 24215581 1152224 complement(2860440..2861027) 1 NC_004342.2 hypothetical protein 2861027 1152224 LA_2881 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713062.1 2860440 R 189518 CDS NP_713063.2 294828203 1152225 complement(2861050..2861556) 1 NC_004342.2 hypothetical protein 2861556 1152225 LA_2882 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713063.2 2861050 R 189518 CDS NP_713064.1 24215583 1152226 complement(2861909..2862721) 1 NC_004342.2 phenazine biosynthesis-like protein 2862721 1152226 LA_2883 Leptospira interrogans serovar Lai str. 56601 phenazine biosynthesis-like protein NP_713064.1 2861909 R 189518 CDS NP_713065.2 294828204 1152227 complement(2863226..2863762) 1 NC_004342.2 hypothetical protein 2863762 1152227 LA_2884 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713065.2 2863226 R 189518 CDS NP_713067.2 294828205 1152229 2864188..2865606 1 NC_004342.2 dihydrolipoamide dehydrogenase 2865606 lpd 1152229 lpd Leptospira interrogans serovar Lai str. 56601 dihydrolipoamide dehydrogenase NP_713067.2 2864188 D 189518 CDS NP_713068.1 24215587 1152230 complement(2865603..2866040) 1 NC_004342.2 ferric uptake regulator 2866040 fur 1152230 fur Leptospira interrogans serovar Lai str. 56601 ferric uptake regulator NP_713068.1 2865603 R 189518 CDS NP_713072.2 294828206 1152234 2867393..2868850 1 NC_004342.2 Na+/H+ antiporter 2868850 1152234 LA_2891 Leptospira interrogans serovar Lai str. 56601 Na+/H+ antiporter NP_713072.2 2867393 D 189518 CDS NP_713073.1 24215592 1152235 complement(2869399..2870385) 1 NC_004342.2 hypothetical protein 2870385 1152235 LA_2892 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713073.1 2869399 R 189518 CDS NP_713075.1 24215594 1152237 complement(2870776..2871387) 1 NC_004342.2 transcriptional regulator 2871387 1152237 LA_2894 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_713075.1 2870776 R 189518 CDS NP_713077.1 24215596 1152239 2871988..2872866 1 NC_004342.2 ribosomal large subunit pseudouridine synthase 2872866 rluA 1152239 rluA Leptospira interrogans serovar Lai str. 56601 ribosomal large subunit pseudouridine synthase NP_713077.1 2871988 D 189518 CDS NP_713080.1 24215599 1152242 complement(2873669..2874394) 1 NC_004342.2 methyltransferase 2874394 1152242 LA_2899 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_713080.1 2873669 R 189518 CDS NP_713081.1 24215600 1152243 complement(2875003..2875815) 1 NC_004342.2 hypothetical protein 2875815 1152243 LA_2900 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713081.1 2875003 R 189518 CDS NP_713082.2 294828207 1152244 complement(2875816..2876604) 1 NC_004342.2 M23 family metalloendopeptidase 2876604 nlpD 1152244 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_713082.2 2875816 R 189518 CDS NP_713084.1 24215603 1152246 complement(2878142..2878780) 1 NC_004342.2 Holliday junction DNA helicase RuvA 2878780 ruvA 1152246 ruvA Leptospira interrogans serovar Lai str. 56601 Holliday junction DNA helicase RuvA NP_713084.1 2878142 R 189518 CDS NP_713086.1 24215605 1152248 complement(2879462..2879941) 1 NC_004342.2 flavin reductase-like protein 2879941 1152248 LA_2905 Leptospira interrogans serovar Lai str. 56601 flavin reductase-like protein NP_713086.1 2879462 R 189518 CDS NP_713088.1 24215607 1152250 complement(2880216..2881169) 1 NC_004342.2 transcriptional regulator 2881169 1152250 LA_2907 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_713088.1 2880216 R 189518 CDS NP_713089.1 24215608 1152251 2881688..2882086 1 NC_004342.2 short-chain dehydrogenase 2882086 1152251 LA_2908 Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_713089.1 2881688 D 189518 CDS NP_713090.1 24215609 1152252 2882050..2882490 1 NC_004342.2 short-chain dehydrogenase 2882490 1152252 LA_2909 Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_713090.1 2882050 D 189518 CDS NP_713091.1 24215610 1152253 2882958..2883347 1 NC_004342.2 hypothetical protein 2883347 1152253 LA_2910 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713091.1 2882958 D 189518 CDS NP_713094.2 294828208 1152256 2884033..2884878 1 NC_004342.2 ISlin1 transposase 2884878 1152256 LA_2914 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713094.2 2884033 D 189518 CDS YP_003573331.1 294828209 9006937 2884897..2885202 1 NC_004342.2 ISlin1 transposase 2885202 9006937 LA_2914a Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase YP_003573331.1 2884897 D 189518 CDS NP_713095.1 24215614 1152257 complement(2886000..2886590) 1 NC_004342.2 metal-dependent phosphohydrolase 2886590 1152257 LA_2915 Leptospira interrogans serovar Lai str. 56601 metal-dependent phosphohydrolase NP_713095.1 2886000 R 189518 CDS NP_713096.1 24215615 1152258 complement(2886963..2888342) 1 NC_004342.2 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 2888342 1152258 LA_2916 Leptospira interrogans serovar Lai str. 56601 DNA repair protein RadA NP_713096.1 2886963 R 189518 CDS NP_713097.1 24215616 1152259 complement(2888339..2888977) 1 NC_004342.2 ribonuclease D 2888977 rnd 1152259 rnd Leptospira interrogans serovar Lai str. 56601 ribonuclease D NP_713097.1 2888339 R 189518 CDS NP_713098.1 24215617 1152260 2889094..2891034 1 NC_004342.2 alpha-galactosidase 2891034 1152260 LA_2918 Leptospira interrogans serovar Lai str. 56601 alpha-galactosidase NP_713098.1 2889094 D 189518 CDS NP_713099.2 294828210 1152261 2891088..2891573 1 NC_004342.2 hypothetical protein 2891573 1152261 LA_2919 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713099.2 2891088 D 189518 CDS NP_713100.2 294828211 1152262 2891921..2893411 1 NC_004342.2 hypothetical protein 2893411 1152262 LA_2920 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713100.2 2891921 D 189518 CDS NP_713101.1 24215620 1152263 complement(2894117..2895226) 1 NC_004342.2 two-component response regulator 2895226 1152263 LA_2921 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_713101.1 2894117 R 189518 CDS NP_713102.1 24215621 1152264 complement(2895228..2896043) 1 NC_004342.2 hypothetical protein 2896043 1152264 LA_2922 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713102.1 2895228 R 189518 CDS NP_713103.1 24215622 1152265 complement(2896046..2896954) 1 NC_004342.2 histone deacetylase 2896954 acuC 1152265 acuC Leptospira interrogans serovar Lai str. 56601 histone deacetylase NP_713103.1 2896046 R 189518 CDS NP_713104.2 294828212 1152266 2897057..2898484 1 NC_004342.2 pyruvate kinase 2898484 pykF 1152266 pykF Leptospira interrogans serovar Lai str. 56601 pyruvate kinase NP_713104.2 2897057 D 189518 CDS NP_713106.2 294828213 1152268 2899919..2900860 1 NC_004342.2 GGDEF family protein 2900860 1152268 LA_2926 Leptospira interrogans serovar Lai str. 56601 GGDEF family protein NP_713106.2 2899919 D 189518 CDS NP_713108.1 24215627 1152270 2900981..2901928 1 NC_004342.2 GGDEF family protein 2901928 1152270 LA_2927 Leptospira interrogans serovar Lai str. 56601 GGDEF family protein NP_713108.1 2900981 D 189518 CDS NP_713109.1 24215628 1152271 2901948..2902901 1 NC_004342.2 GGDEF family protein 2902901 1152271 LA_2929 Leptospira interrogans serovar Lai str. 56601 GGDEF family protein NP_713109.1 2901948 D 189518 CDS NP_713110.1 24215629 1152272 2902925..2903851 1 NC_004342.2 GGDEF family protein 2903851 1152272 LA_2930 Leptospira interrogans serovar Lai str. 56601 GGDEF family protein NP_713110.1 2902925 D 189518 CDS NP_713111.1 24215630 1152273 2903938..2904879 1 NC_004342.2 GGDEF family protein 2904879 1152273 LA_2931 Leptospira interrogans serovar Lai str. 56601 GGDEF family protein NP_713111.1 2903938 D 189518 CDS NP_713112.2 294828214 1152274 2904968..2905888 1 NC_004342.2 GGDEF family protein 2905888 1152274 LA_2932 Leptospira interrogans serovar Lai str. 56601 GGDEF family protein NP_713112.2 2904968 D 189518 CDS NP_713113.1 24215632 1152275 2905995..2906957 1 NC_004342.2 GGDEF family protein 2906957 1152275 LA_2933 Leptospira interrogans serovar Lai str. 56601 GGDEF family protein NP_713113.1 2905995 D 189518 CDS NP_713114.1 24215633 1152276 complement(2907018..2908268) 1 NC_004342.2 chloride channel protein EriC 2908268 eriC 1152276 eriC Leptospira interrogans serovar Lai str. 56601 chloride channel protein EriC NP_713114.1 2907018 R 189518 CDS NP_713115.2 294828215 1152277 complement(2908279..2909391) 1 NC_004342.2 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2909391 purM 1152277 purM Leptospira interrogans serovar Lai str. 56601 phosphoribosylaminoimidazole synthetase NP_713115.2 2908279 R 189518 CDS NP_713116.2 294828216 1152278 complement(2909437..2910045) 1 NC_004342.2 hypothetical protein 2910045 1152278 LA_2936 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713116.2 2909437 R 189518 CDS NP_713120.1 24215639 1152282 complement(2911487..2912536) 1 NC_004342.2 hypothetical protein 2912536 1152282 LA_2940 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713120.1 2911487 R 189518 CDS NP_713121.1 24215640 1152283 complement(2912523..2912825) 1 NC_004342.2 hypothetical protein 2912825 1152283 LA_2941 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713121.1 2912523 R 189518 CDS NP_713122.2 294828217 1152284 2913448..2914650 1 NC_004342.2 hypothetical protein 2914650 1152284 LA_2942 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713122.2 2913448 D 189518 CDS NP_713123.1 24215642 1152285 complement(2914869..2915285) 1 NC_004342.2 hypothetical protein 2915285 1152285 LA_2943 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713123.1 2914869 R 189518 CDS NP_713124.1 24215643 1152286 complement(2915350..2917509) 1 NC_004342.2 alpha-glucosidase 2917509 1152286 LA_2944 Leptospira interrogans serovar Lai str. 56601 alpha-glucosidase NP_713124.1 2915350 R 189518 CDS NP_713126.1 24215645 1152288 complement(2917782..2918099) 1 NC_004342.2 hypothetical protein 2918099 1152288 LA_2946 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713126.1 2917782 R 189518 CDS NP_713127.2 294828218 1152289 complement(2918298..2919155) 1 NC_004342.2 thiosulfate sulfurtransferase 2919155 sseA 1152289 sseA Leptospira interrogans serovar Lai str. 56601 thiosulfate sulfurtransferase NP_713127.2 2918298 R 189518 CDS YP_003573332.1 294828219 9006938 complement(2919201..2919395) 1 NC_004342.2 hypothetical protein 2919395 9006938 LA_2947a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573332.1 2919201 R 189518 CDS NP_713128.1 24215647 1152290 2919441..2920232 1 NC_004342.2 hypothetical protein 2920232 1152290 LA_2948 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713128.1 2919441 D 189518 CDS NP_713129.1 24215648 1152291 2920225..2921679 1 NC_004342.2 serine protease 2921679 1152291 LA_2949 Leptospira interrogans serovar Lai str. 56601 serine protease NP_713129.1 2920225 D 189518 CDS NP_713130.1 24215649 1152292 2921676..2923013 1 NC_004342.2 hypothetical protein 2923013 1152292 LA_2950 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713130.1 2921676 D 189518 CDS NP_713131.1 24215650 1152293 2923050..2923964 1 NC_004342.2 two-component hybrid sensor and regulator 2923964 1152293 LA_2951 Leptospira interrogans serovar Lai str. 56601 two-component hybrid sensor and regulator NP_713131.1 2923050 D 189518 CDS NP_713132.1 24215651 1152294 complement(2923944..2925656) 1 NC_004342.2 hypothetical protein 2925656 1152294 LA_2952 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713132.1 2923944 R 189518 CDS NP_713133.1 24215652 1152295 complement(2925653..2926939) 1 NC_004342.2 polysaccharide biosynthesis protein 2926939 1152295 LA_2953 Leptospira interrogans serovar Lai str. 56601 polysaccharide biosynthesis protein NP_713133.1 2925653 R 189518 CDS NP_713134.1 24215653 1152296 complement(2926941..2927906) 1 NC_004342.2 membrane associated acid phosphatase 2927906 1152296 LA_2954 Leptospira interrogans serovar Lai str. 56601 membrane associated acid phosphatase NP_713134.1 2926941 R 189518 CDS NP_713135.1 24215654 1152297 2928143..2928940 1 NC_004342.2 acyltransferase 2928940 plsC 1152297 plsC Leptospira interrogans serovar Lai str. 56601 acyltransferase NP_713135.1 2928143 D 189518 CDS NP_713136.1 24215655 1152298 2928977..2932354 1 NC_004342.2 methylmalonyl-CoA mutase 2932354 1152298 LA_2956 Leptospira interrogans serovar Lai str. 56601 methylmalonyl-CoA mutase NP_713136.1 2928977 D 189518 CDS NP_713137.1 24215656 1152299 2932635..2933306 1 NC_004342.2 aminopeptidase 2933306 1152299 LA_2957 Leptospira interrogans serovar Lai str. 56601 aminopeptidase NP_713137.1 2932635 D 189518 CDS NP_713138.1 24215657 1152300 2934302..2935435 1 NC_004342.2 hypothetical protein 2935435 1152300 LA_2958 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713138.1 2934302 D 189518 CDS NP_713139.1 24215658 1152301 complement(2936729..2938411) 1 NC_004342.2 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 2938411 ilvD 1152301 ilvD Leptospira interrogans serovar Lai str. 56601 dihydroxy-acid dehydratase NP_713139.1 2936729 R 189518 CDS NP_713143.1 24215662 1152305 2939845..2940396 1 NC_004342.2 membrane-bound metal-dependent hydrolase 2940396 1152305 LA_2963 Leptospira interrogans serovar Lai str. 56601 membrane-bound metal-dependent hydrolase NP_713143.1 2939845 D 189518 CDS NP_713145.1 24215664 1152307 2940758..2942038 1 NC_004342.2 hypothetical protein 2942038 1152307 LA_2964 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713145.1 2940758 D 189518 CDS NP_713146.1 24215665 1152308 2942066..2943292 1 NC_004342.2 cytoplasmic membrane protein 2943292 1152308 LA_2966 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713146.1 2942066 D 189518 CDS NP_713147.1 24215666 1152309 2943289..2943603 1 NC_004342.2 hypothetical protein 2943603 1152309 LA_2967 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713147.1 2943289 D 189518 CDS NP_713148.1 24215667 1152310 complement(2943600..2944925) 1 NC_004342.2 guanylate cyclase 2944925 cyaA 1152310 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_713148.1 2943600 R 189518 CDS NP_713149.1 24215668 1152311 complement(2945729..2946622) 1 NC_004342.2 glycosyltransferase 2946622 1152311 LA_2969 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_713149.1 2945729 R 189518 CDS NP_713150.1 24215669 1152312 complement(2946996..2949056) 1 NC_004342.2 hypothetical protein 2949056 1152312 LA_2971 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713150.1 2946996 R 189518 CDS NP_713151.2 294828220 1152313 2949196..2949498 1 NC_004342.2 hypothetical protein 2949498 1152313 LA_2970 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713151.2 2949196 D 189518 CDS NP_713152.1 24215671 1152314 2949495..2949932 1 NC_004342.2 hypothetical protein 2949932 1152314 LA_2972 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713152.1 2949495 D 189518 CDS NP_713153.1 24215672 1152315 2950048..2950995 1 NC_004342.2 hypothetical protein 2950995 1152315 LA_2973 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713153.1 2950048 D 189518 CDS NP_713154.2 294828221 1152316 2951042..2952241 1 NC_004342.2 cytochrome c peroxidase 2952241 mauG 1152316 mauG Leptospira interrogans serovar Lai str. 56601 cytochrome c peroxidase NP_713154.2 2951042 D 189518 CDS NP_713155.1 24215674 1152317 2952213..2953091 1 NC_004342.2 hypothetical protein 2953091 1152317 LA_2975 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713155.1 2952213 D 189518 CDS NP_713156.1 24215675 1152318 2953091..2954077 1 NC_004342.2 hypothetical protein 2954077 1152318 LA_2976 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713156.1 2953091 D 189518 CDS NP_713157.1 24215676 1152319 2954259..2955623 1 NC_004342.2 tRNA (uracil-5-)-methyltransferase 2955623 trmA 1152319 trmA Leptospira interrogans serovar Lai str. 56601 tRNA (uracil-5-)-methyltransferase NP_713157.1 2954259 D 189518 CDS NP_713158.1 24215677 1152320 complement(2956213..2957358) 1 NC_004342.2 hypothetical protein 2957358 1152320 LA_2978 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713158.1 2956213 R 189518 CDS NP_713160.1 24215679 1152322 2957803..2958927 1 NC_004342.2 stage II sporulation protein 2958927 spoIID 1152322 spoIID Leptospira interrogans serovar Lai str. 56601 stage II sporulation protein NP_713160.1 2957803 D 189518 CDS NP_713162.2 294828222 1152324 2959648..2960343 1 NC_004342.2 antimicrobial peptide ABC transporter ATPase 2960343 salX 1152324 salX Leptospira interrogans serovar Lai str. 56601 antimicrobial peptide ABC transporter ATPase NP_713162.2 2959648 D 189518 CDS NP_713163.1 24215682 1152325 2960349..2962823 1 NC_004342.2 ABC transporter integral membrane protein 2962823 1152325 LA_2983 Leptospira interrogans serovar Lai str. 56601 ABC transporter integral membrane protein NP_713163.1 2960349 D 189518 CDS NP_713164.1 24215683 1152326 2962884..2963795 1 NC_004342.2 hypothetical protein 2963795 1152326 LA_2984 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713164.1 2962884 D 189518 CDS NP_713166.1 24215685 1152328 2964627..2965319 1 NC_004342.2 hypothetical protein 2965319 1152328 LA_2986 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713166.1 2964627 D 189518 CDS NP_713167.2 294828223 1152329 complement(2965367..2966089) 1 NC_004342.2 hypothetical protein 2966089 1152329 LA_2987 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713167.2 2965367 R 189518 CDS NP_713168.1 24215687 1152330 complement(2966067..2966651) 1 NC_004342.2 uridine 5-monophosphate synthase 2966651 pyrE 1152330 pyrE Leptospira interrogans serovar Lai str. 56601 uridine 5-monophosphate synthase NP_713168.1 2966067 R 189518 CDS NP_713170.1 24215689 1152332 2966747..2968675 1 NC_004342.2 NH(3)-dependent NAD(+) synthetase 2968675 nadE 1152332 nadE Leptospira interrogans serovar Lai str. 56601 NH(3)-dependent NAD(+) synthetase NP_713170.1 2966747 D 189518 CDS NP_713172.1 24215691 1152334 complement(2969599..2970297) 1 NC_004342.2 hypothetical protein 2970297 1152334 LA_2992 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713172.1 2969599 R 189518 CDS NP_713173.2 294828224 1152335 2970412..2971152 1 NC_004342.2 hypothetical protein 2971152 1152335 LA_2993 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713173.2 2970412 D 189518 CDS NP_713174.1 24215693 1152336 2971149..2971901 1 NC_004342.2 tetrapyrrole (corrin/porphyrin) methylase 2971901 1152336 LA_2994 Leptospira interrogans serovar Lai str. 56601 tetrapyrrole (corrin/porphyrin) methylase NP_713174.1 2971149 D 189518 CDS NP_713175.1 24215694 1152337 2971914..2972237 1 NC_004342.2 hypothetical protein 2972237 1152337 LA_2995 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713175.1 2971914 D 189518 CDS NP_713176.1 24215695 1152338 2972314..2973480 1 NC_004342.2 alcohol dehydrogenase 2973480 eutG 1152338 eutG Leptospira interrogans serovar Lai str. 56601 alcohol dehydrogenase NP_713176.1 2972314 D 189518 CDS NP_713177.2 294828225 1152339 2974495..2975217 1 NC_004342.2 lysozyme precursor 2975217 acm 1152339 acm Leptospira interrogans serovar Lai str. 56601 lysozyme precursor NP_713177.2 2974495 D 189518 CDS NP_713178.1 24215697 1152340 2975848..2976168 1 NC_004342.2 cell shape determination protein 2976168 1152340 LA_2998 Leptospira interrogans serovar Lai str. 56601 cell shape determination protein NP_713178.1 2975848 D 189518 CDS NP_713179.1 24215698 1152341 2976171..2978102 1 NC_004342.2 single-stranded DNA exonuclease 2978102 recJ 1152341 recJ Leptospira interrogans serovar Lai str. 56601 single-stranded DNA exonuclease NP_713179.1 2976171 D 189518 CDS NP_713182.1 24215701 1152344 complement(2978924..2980387) 1 NC_004342.2 tRNA nucleotidyltransferase/poly A polymerase 2980387 pcnB 1152344 pcnB Leptospira interrogans serovar Lai str. 56601 tRNA nucleotidyltransferase/poly A polymerase NP_713182.1 2978924 R 189518 CDS NP_713183.1 24215702 1152345 2980441..2981457 1 NC_004342.2 M23 family metalloendopeptidase 2981457 nlpD 1152345 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_713183.1 2980441 D 189518 CDS NP_713184.1 24215703 1152346 2981856..2982812 1 NC_004342.2 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 2982812 1152346 LA_3004 Leptospira interrogans serovar Lai str. 56601 prolipoprotein diacylglyceryl transferase NP_713184.1 2981856 D 189518 CDS NP_713185.1 24215704 1152347 complement(2983481..2984104) 1 NC_004342.2 methyltransferase 2984104 1152347 LA_3005 Leptospira interrogans serovar Lai str. 56601 methyltransferase NP_713185.1 2983481 R 189518 CDS NP_713191.1 24215710 1152353 complement(2985723..2988569) 1 NC_004342.2 cell division protein with ATPase domain 2988569 ftsK 1152353 ftsK Leptospira interrogans serovar Lai str. 56601 cell division protein with ATPase domain NP_713191.1 2985723 R 189518 CDS NP_713192.1 24215711 1152354 2988805..2990175 1 NC_004342.2 hypothetical protein 2990175 1152354 LA_3012 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713192.1 2988805 D 189518 CDS NP_713195.1 24215714 1152357 2991052..2991189 1 NC_004342.2 hypothetical protein 2991189 1152357 LA_3015 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713195.1 2991052 D 189518 CDS NP_713196.1 24215715 1152358 2991213..2991485 1 NC_004342.2 hypothetical protein 2991485 1152358 LA_3016 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713196.1 2991213 D 189518 CDS NP_713197.2 294828226 1152359 2991552..2992148 1 NC_004342.2 hypothetical protein 2992148 lemA 1152359 lemA Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713197.2 2991552 D 189518 CDS NP_713198.1 24215717 1152360 2992311..2993678 1 NC_004342.2 hypothetical protein 2993678 1152360 LA_3018 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713198.1 2992311 D 189518 CDS NP_713199.1 24215718 1152361 2993694..2994257 1 NC_004342.2 hypothetical protein 2994257 1152361 LA_3019 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713199.1 2993694 D 189518 CDS NP_713200.1 24215719 1152362 2994261..2994626 1 NC_004342.2 hypothetical protein 2994626 mmcQ 1152362 mmcQ Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713200.1 2994261 D 189518 CDS NP_713202.2 294828227 1152364 complement(2995371..2995769) 1 NC_004342.2 Fe-S metabolism protein 2995769 1152364 LA_3022 Leptospira interrogans serovar Lai str. 56601 Fe-S metabolism protein NP_713202.2 2995371 R 189518 CDS NP_713204.1 24215723 1152366 2996831..2997472 1 NC_004342.2 hypothetical protein 2997472 1152366 LA_3024 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713204.1 2996831 D 189518 CDS NP_713205.1 24215724 1152367 complement(2997528..2997773) 1 NC_004342.2 hypothetical protein 2997773 1152367 LA_3025 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713205.1 2997528 R 189518 CDS NP_713206.1 24215725 1152368 complement(2998478..2999575) 1 NC_004342.2 hypothetical protein 2999575 1152368 LA_3026 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713206.1 2998478 R 189518 CDS NP_713208.1 24215727 1152370 3000692..3002749 1 NC_004342.2 hypothetical protein 3002749 1152370 LA_3028 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713208.1 3000692 D 189518 CDS NP_713209.1 24215728 1152371 complement(3002918..3004333) 1 NC_004342.2 ankyrin G domain-containing protein 3004333 1152371 LA_3029 Leptospira interrogans serovar Lai str. 56601 ankyrin G domain-containing protein NP_713209.1 3002918 R 189518 CDS NP_713211.2 294828228 1152373 3004965..3005903 1 NC_004342.2 hypothetical protein 3005903 1152373 LA_3031 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713211.2 3004965 D 189518 CDS NP_713213.1 24215732 1152375 3006111..3006941 1 NC_004342.2 molybdate metabolism regulator 3006941 1152375 LA_3033 Leptospira interrogans serovar Lai str. 56601 molybdate metabolism regulator NP_713213.1 3006111 D 189518 CDS NP_713216.1 24215735 1152378 complement(3007604..3007930) 1 NC_004342.2 hypothetical protein 3007930 1152378 LA_3036 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713216.1 3007604 R 189518 CDS NP_713219.1 24215738 1152381 complement(3008382..3009554) 1 NC_004342.2 hypothetical protein 3009554 1152381 LA_3039 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713219.1 3008382 R 189518 CDS NP_713221.1 24215740 1152383 3010338..3011594 1 NC_004342.2 guanylate cyclase 3011594 cyaA 1152383 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_713221.1 3010338 D 189518 CDS NP_713222.2 294828229 1152384 3011835..3012314 1 NC_004342.2 hypothetical protein 3012314 1152384 LA_3042 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713222.2 3011835 D 189518 CDS NP_713225.1 24215744 1152387 3012889..3013104 1 NC_004342.2 hypothetical protein 3013104 1152387 LA_3044 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713225.1 3012889 D 189518 CDS NP_713227.2 294828230 1152389 3013317..3013862 1 NC_004342.2 hypothetical protein 3013862 1152389 LA_3047 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713227.2 3013317 D 189518 CDS NP_713229.1 24215748 1152391 3015310..3015732 1 NC_004342.2 hypothetical protein 3015732 1152391 LA_3049 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713229.1 3015310 D 189518 CDS NP_713230.1 24215749 1152392 complement(3015835..3016554) 1 NC_004342.2 hemolysin 3016554 1152392 LA_3050 Leptospira interrogans serovar Lai str. 56601 hemolysin NP_713230.1 3015835 R 189518 CDS NP_713231.1 24215750 1152393 complement(3016897..3017667) 1 NC_004342.2 glutamate racemase 3017667 murI 1152393 murI Leptospira interrogans serovar Lai str. 56601 glutamate racemase NP_713231.1 3016897 R 189518 CDS NP_713232.1 24215751 1152394 complement(3017700..3019004) 1 NC_004342.2 aminotransferase 3019004 1152394 LA_3052 Leptospira interrogans serovar Lai str. 56601 aminotransferase NP_713232.1 3017700 R 189518 CDS NP_713233.2 294828231 1152395 complement(3019045..3020142) 1 NC_004342.2 trypsin-like serine protease 3020142 degQ 1152395 degQ Leptospira interrogans serovar Lai str. 56601 trypsin-like serine protease NP_713233.2 3019045 R 189518 CDS NP_713234.1 24215753 1152396 3020141..3021247 1 NC_004342.2 aminopeptidase 3021247 1152396 LA_3053 Leptospira interrogans serovar Lai str. 56601 aminopeptidase NP_713234.1 3020141 D 189518 CDS NP_713235.1 24215754 1152397 3021274..3021651 1 NC_004342.2 hypothetical protein 3021651 1152397 LA_3055 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713235.1 3021274 D 189518 CDS NP_713236.1 24215755 1152398 3021679..3022641 1 NC_004342.2 hypothetical protein 3022641 1152398 LA_3056 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713236.1 3021679 D 189518 CDS NP_713239.1 24215758 1152401 complement(3023439..3023798) 1 NC_004342.2 ISlin1 transposase 3023798 1152401 LA_3059 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713239.1 3023439 R 189518 CDS NP_713240.1 24215759 1152402 complement(3023791..3024138) 1 NC_004342.2 ISlin1 transposase 3024138 1152402 LA_3060 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713240.1 3023791 R 189518 CDS NP_713241.2 294828232 1152403 complement(3024254..3024382) 1 NC_004342.2 ISlin1 transposase 3024382 1152403 LA_3061 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713241.2 3024254 R 189518 CDS NP_713242.1 24215761 1152404 complement(3024585..3024746) 1 NC_004342.2 ISlin1 transposase 3024746 1152404 LA_3062 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713242.1 3024585 R 189518 CDS NP_713245.1 24215764 1152407 3025737..3026771 1 NC_004342.2 hypothetical protein 3026771 1152407 LA_3064 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713245.1 3025737 D 189518 CDS NP_713247.1 24215766 1152409 complement(3027844..3035610) 1 NC_004342.2 TolB-like protein 3035610 1152409 LA_3067 Leptospira interrogans serovar Lai str. 56601 TolB-like protein NP_713247.1 3027844 R 189518 CDS NP_713248.2 294828233 1152410 complement(3035614..3036210) 1 NC_004342.2 hypothetical protein 3036210 1152410 LA_3068 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713248.2 3035614 R 189518 CDS NP_713249.1 24215768 1152411 complement(3036224..3039232) 1 NC_004342.2 hypothetical protein 3039232 1152411 LA_3069 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713249.1 3036224 R 189518 CDS NP_713250.1 24215769 1152412 complement(3039256..3039597) 1 NC_004342.2 anti-sigma-factor antagonist 3039597 1152412 LA_3070 Leptospira interrogans serovar Lai str. 56601 anti-sigma-factor antagonist NP_713250.1 3039256 R 189518 CDS NP_713251.1 24215770 1152413 3039775..3040770 1 NC_004342.2 glycosyltransferase 3040770 1152413 LA_3071 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_713251.1 3039775 D 189518 CDS NP_713252.1 24215771 1152414 3040803..3042683 1 NC_004342.2 hypothetical protein 3042683 1152414 LA_3072 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713252.1 3040803 D 189518 CDS NP_713253.1 24215772 1152415 3042778..3042897 1 NC_004342.2 transposase 3042897 1152415 LA_3073 Leptospira interrogans serovar Lai str. 56601 transposase NP_713253.1 3042778 D 189518 CDS NP_713255.2 294828234 1152417 3044638..3050502 1 NC_004342.2 LigB-like protein 3050502 1152417 LA_3075 Leptospira interrogans serovar Lai str. 56601 LigB-like protein NP_713255.2 3044638 D 189518 CDS NP_713256.1 24215775 1152418 3050515..3050901 1 NC_004342.2 hypothetical protein 3050901 1152418 LA_3076 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713256.1 3050515 D 189518 CDS NP_713257.1 24215776 1152419 3050889..3051413 1 NC_004342.2 hypothetical protein 3051413 1152419 LA_3077 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713257.1 3050889 D 189518 CDS NP_713258.1 24215777 1152420 complement(3051451..3052269) 1 NC_004342.2 sterol desaturase 3052269 1152420 LA_3078 Leptospira interrogans serovar Lai str. 56601 sterol desaturase NP_713258.1 3051451 R 189518 CDS NP_713259.1 24215778 1152421 complement(3054457..3055239) 1 NC_004342.2 hypothetical protein 3055239 1152421 LA_3079 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713259.1 3054457 R 189518 CDS NP_713260.1 24215779 1152422 complement(3055240..3056541) 1 NC_004342.2 adenylosuccinate lyase 3056541 purB 1152422 purB Leptospira interrogans serovar Lai str. 56601 adenylosuccinate lyase NP_713260.1 3055240 R 189518 CDS NP_713263.1 24215782 1152425 complement(3057241..3058308) 1 NC_004342.2 hypothetical protein 3058308 1152425 LA_3083 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713263.1 3057241 R 189518 CDS NP_713264.2 294828235 1152426 complement(3058319..3060118) 1 NC_004342.2 nickel ABC transporter periplasmic protein OppA 3060118 1152426 LA_3084 Leptospira interrogans serovar Lai str. 56601 nickel ABC transporter periplasmic protein OppA NP_713264.2 3058319 R 189518 CDS NP_713265.2 294828236 1152427 complement(3060132..3062156) 1 NC_004342.2 guanosine polyphosphate pyrophosphohydrolase/synthetase 3062156 spoT 1152427 spoT Leptospira interrogans serovar Lai str. 56601 guanosine polyphosphate pyrophosphohydrolase/synthetase NP_713265.2 3060132 R 189518 CDS NP_713266.1 24215785 1152428 complement(3062161..3063075) 1 NC_004342.2 nicotinate-nucleotide pyrophosphorylase 3063075 nadC 1152428 nadC Leptospira interrogans serovar Lai str. 56601 nicotinate-nucleotide pyrophosphorylase NP_713266.1 3062161 R 189518 CDS NP_713271.2 294828237 1152433 3067623..3068360 1 NC_004342.2 hypothetical protein 3068360 1152433 LA_3091 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713271.2 3067623 D 189518 CDS NP_713272.2 294828238 1152434 complement(3069204..3070826) 1 NC_004342.2 hypothetical protein 3070826 1152434 LA_3093 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713272.2 3069204 R 189518 CDS YP_003573333.1 294828239 9006940 complement(3070834..3071031) 1 NC_004342.2 hypothetical protein 3071031 9006940 LA_3093a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573333.1 3070834 R 189518 CDS NP_713273.1 24215792 1152435 3071047..3071607 1 NC_004342.2 hypothetical protein 3071607 1152435 LA_3092 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713273.1 3071047 D 189518 CDS NP_713274.1 24215793 1152436 3071638..3072120 1 NC_004342.2 ferric uptake regulator 3072120 fur 1152436 fur Leptospira interrogans serovar Lai str. 56601 ferric uptake regulator NP_713274.1 3071638 D 189518 CDS NP_713275.1 24215794 1152437 3072117..3073241 1 NC_004342.2 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 3073241 tgt 1152437 tgt Leptospira interrogans serovar Lai str. 56601 queuine tRNA-ribosyltransferase NP_713275.1 3072117 D 189518 CDS NP_713276.1 24215795 1152438 3073312..3073647 1 NC_004342.2 anti-sigma factor antagonist 3073647 spoIIAA 1152438 spoIIAA Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_713276.1 3073312 D 189518 CDS NP_713277.1 24215796 1152439 3073695..3075362 1 NC_004342.2 hypothetical protein 3075362 lipL71 1152439 lipL71 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713277.1 3073695 D 189518 CDS YP_003573334.1 294828240 9006941 complement(3077066..3077362) 1 NC_004342.2 IS1533 transposase 3077362 9006941 LA_3097a Leptospira interrogans serovar Lai str. 56601 IS1533 transposase YP_003573334.1 3077066 R 189518 CDS NP_713279.1 24215798 1152441 complement(3077447..3077818) 1 NC_004342.2 IS1533 transposase 3077818 1152441 LA_3099 Leptospira interrogans serovar Lai str. 56601 IS1533 transposase NP_713279.1 3077447 R 189518 CDS NP_713280.2 294828241 1152442 complement(3078003..3078890) 1 NC_004342.2 short-chain dehydrogenase 3078890 1152442 LA_3100 Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_713280.2 3078003 R 189518 CDS NP_713281.2 294828242 1152443 3079383..3080330 1 NC_004342.2 SAM-dependent methyltransferase 3080330 1152443 LA_3101 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_713281.2 3079383 D 189518 CDS NP_713282.1 24215801 1152444 complement(3080421..3082700) 1 NC_004342.2 hypothetical protein 3082700 1152444 LA_3102 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713282.1 3080421 R 189518 CDS NP_713283.1 24215802 1152445 complement(3083319..3083717) 1 NC_004342.2 hypothetical protein 3083717 1152445 LA_3103 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713283.1 3083319 R 189518 CDS NP_713284.1 24215803 1152446 complement(3084144..3085037) 1 NC_004342.2 signal transduction protein 3085037 rtn 1152446 rtn Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_713284.1 3084144 R 189518 CDS NP_713285.1 24215804 1152447 3085038..3085253 1 NC_004342.2 hypothetical protein 3085253 1152447 LA_3105 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713285.1 3085038 D 189518 CDS NP_713288.1 24215807 1152450 complement(3087475..3088158) 1 NC_004342.2 response regulator containing a signal receiver domain and a DNA/RNA polymerase-binding domain 3088158 1152450 LA_3108 Leptospira interrogans serovar Lai str. 56601 response regulator containing a signal receiver domain and a DNA/RNA polymerase-binding domain NP_713288.1 3087475 R 189518 CDS NP_713289.1 24215808 1152451 complement(3088162..3090774) 1 NC_004342.2 histidine kinase sensor protein 3090774 kdpD 1152451 kdpD Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_713289.1 3088162 R 189518 CDS NP_713290.2 294828243 1152452 complement(3090771..3091343) 1 NC_004342.2 potassium-transporting ATPase subunit C 3091343 kdpC 1152452 kdpC Leptospira interrogans serovar Lai str. 56601 potassium-transporting ATPase subunit C NP_713290.2 3090771 R 189518 CDS NP_713291.2 294828244 1152453 complement(3091354..3093432) 1 NC_004342.2 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 3093432 kdpB 1152453 kdpB Leptospira interrogans serovar Lai str. 56601 potassium-transporting ATPase subunit B NP_713291.2 3091354 R 189518 CDS NP_713292.1 24215811 1152454 complement(3093443..3095116) 1 NC_004342.2 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 3095116 kdpA 1152454 kdpA Leptospira interrogans serovar Lai str. 56601 potassium-transporting ATPase subunit A NP_713292.1 3093443 R 189518 CDS NP_713293.1 24215812 1152455 complement(3095362..3100557) 1 NC_004342.2 serine/threonine kinase 3100557 1152455 LA_3113 Leptospira interrogans serovar Lai str. 56601 serine/threonine kinase NP_713293.1 3095362 R 189518 CDS NP_713294.1 24215813 1152456 complement(3100758..3102821) 1 NC_004342.2 cytoplasmic membrane protein 3102821 1152456 LA_3114 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713294.1 3100758 R 189518 CDS NP_713295.1 24215814 1152457 complement(3102918..3103841) 1 NC_004342.2 hypothetical protein 3103841 1152457 LA_3115 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713295.1 3102918 R 189518 CDS NP_713297.1 24215816 1152459 3105083..3105502 1 NC_004342.2 hypothetical protein 3105502 1152459 LA_3117 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713297.1 3105083 D 189518 CDS NP_713298.1 24215817 1152460 complement(3106282..3107343) 1 NC_004342.2 hypothetical protein 3107343 1152460 LA_3118 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713298.1 3106282 R 189518 CDS NP_713299.1 24215818 1152461 complement(3107345..3108313) 1 NC_004342.2 hypothetical protein 3108313 1152461 LA_3119 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713299.1 3107345 R 189518 CDS NP_713300.1 24215819 1152462 3108384..3109904 1 NC_004342.2 zinc-bindin carboxypeptidase 3109904 1152462 LA_3120 Leptospira interrogans serovar Lai str. 56601 zinc-bindin carboxypeptidase NP_713300.1 3108384 D 189518 CDS NP_713301.2 294828245 1152463 3109970..3110809 1 NC_004342.2 permease 3110809 1152463 LA_3121 Leptospira interrogans serovar Lai str. 56601 permease NP_713301.2 3109970 D 189518 CDS NP_713306.2 294828246 1152468 3112040..3113194 1 NC_004342.2 hypothetical protein 3113194 1152468 LA_3126 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713306.2 3112040 D 189518 CDS NP_713307.1 24215826 1152469 3113199..3114107 1 NC_004342.2 sodium bile acid symporter family protein 3114107 1152469 LA_3127 Leptospira interrogans serovar Lai str. 56601 sodium bile acid symporter family protein NP_713307.1 3113199 D 189518 CDS NP_713308.1 24215827 1152470 complement(3114091..3115194) 1 NC_004342.2 hypothetical protein 3115194 1152470 LA_3128 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713308.1 3114091 R 189518 CDS NP_713313.1 24215832 1152475 3117417..3118598 1 NC_004342.2 transcriptional regulator 3118598 1152475 LA_3133 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_713313.1 3117417 D 189518 CDS NP_713315.1 24215834 1152477 3119822..3121033 1 NC_004342.2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3121033 paaJ 1152477 paaJ Leptospira interrogans serovar Lai str. 56601 acetyl-CoA acetyltransferase NP_713315.1 3119822 D 189518 CDS NP_713317.1 24215836 1152479 complement(3122031..3122429) 1 NC_004342.2 hypothetical protein 3122429 1152479 LA_3137 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713317.1 3122031 R 189518 CDS NP_713318.2 294828247 1152480 3122661..3123623 1 NC_004342.2 OmpL1 3123623 1152480 LA_3138 Leptospira interrogans serovar Lai str. 56601 OmpL1 NP_713318.2 3122661 D 189518 CDS NP_713319.2 294828248 1152481 complement(3123727..3124677) 1 NC_004342.2 cytochrome c peroxidase 3124677 mauG 1152481 mauG Leptospira interrogans serovar Lai str. 56601 cytochrome c peroxidase NP_713319.2 3123727 R 189518 CDS NP_713323.1 24215842 1152485 complement(3126103..3127359) 1 NC_004342.2 acyl-CoA dehydrogenase 3127359 caiA 1152485 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_713323.1 3126103 R 189518 CDS NP_713324.1 24215843 1152486 complement(3127541..3128713) 1 NC_004342.2 acyl-CoA transferase 3128713 caiB 1152486 caiB Leptospira interrogans serovar Lai str. 56601 acyl-CoA transferase NP_713324.1 3127541 R 189518 CDS NP_713325.1 24215844 1152487 3129148..3130224 1 NC_004342.2 hypothetical protein 3130224 1152487 LA_3145 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713325.1 3129148 D 189518 CDS NP_713326.1 24215845 1152488 complement(3130739..3131125) 1 NC_004342.2 cation transporter protein 3131125 1152488 LA_3146 Leptospira interrogans serovar Lai str. 56601 cation transporter protein NP_713326.1 3130739 R 189518 CDS NP_713327.2 294828249 1152489 3131203..3132036 1 NC_004342.2 alpha/beta hydrolase 3132036 1152489 LA_3147 Leptospira interrogans serovar Lai str. 56601 alpha/beta hydrolase NP_713327.2 3131203 D 189518 CDS NP_713328.2 294828250 1152490 3132552..3132845 1 NC_004342.2 hypothetical protein 3132845 1152490 LA_3148 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713328.2 3132552 D 189518 CDS NP_713329.1 24215848 1152491 3132891..3135224 1 NC_004342.2 TonB-dependent outer membrane hemin receptor 3135224 1152491 LA_3149 Leptospira interrogans serovar Lai str. 56601 TonB-dependent outer membrane hemin receptor NP_713329.1 3132891 D 189518 CDS NP_713330.1 24215849 1152492 3135235..3135609 1 NC_004342.2 hypothetical protein 3135609 1152492 LA_3150 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713330.1 3135235 D 189518 CDS NP_713332.2 294828251 1152494 complement(3136153..3136689) 1 NC_004342.2 CopG-like transcriptional regulator 3136689 1152494 LA_3152 Leptospira interrogans serovar Lai str. 56601 CopG-like transcriptional regulator NP_713332.2 3136153 R 189518 CDS NP_713335.1 24215854 1152497 3138456..3139115 1 NC_004342.2 transposase 3139115 1152497 LA_3155 Leptospira interrogans serovar Lai str. 56601 transposase NP_713335.1 3138456 D 189518 CDS NP_713336.2 294828252 1152498 3139468..3140835 1 NC_004342.2 flavin-binding monooxygenase-like protein 3140835 1152498 LA_3156 Leptospira interrogans serovar Lai str. 56601 flavin-binding monooxygenase-like protein NP_713336.2 3139468 D 189518 CDS NP_713338.1 24215857 1152500 complement(3141260..3142273) 1 NC_004342.2 Zn-dependent alcohol dehydrogenase 3142273 adhP 1152500 adhP Leptospira interrogans serovar Lai str. 56601 Zn-dependent alcohol dehydrogenase NP_713338.1 3141260 R 189518 CDS YP_003573335.1 294828253 9006943 complement(3142488..3142721) 1 NC_004342.2 hypothetical protein 3142721 9006943 LA_3158a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573335.1 3142488 R 189518 CDS NP_713340.1 24215859 1152502 3143060..3145051 1 NC_004342.2 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase 3145051 gcpE 1152502 gcpE Leptospira interrogans serovar Lai str. 56601 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase NP_713340.1 3143060 D 189518 CDS NP_713342.1 24215861 1152504 3145143..3145295 1 NC_004342.2 hypothetical protein 3145295 1152504 LA_3161 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713342.1 3145143 D 189518 CDS NP_713341.2 294828254 1152503 complement(3145267..3145491) 1 NC_004342.2 hypothetical protein 3145491 1152503 LA_3162 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713341.2 3145267 R 189518 CDS NP_713344.2 294828255 1152506 complement(3146622..3147287) 1 NC_004342.2 hypothetical protein 3147287 1152506 LA_3165 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713344.2 3146622 R 189518 CDS NP_713346.1 24215865 1152508 complement(3147588..3148430) 1 NC_004342.2 metallophosphoesterase 3148430 1152508 LA_3166 Leptospira interrogans serovar Lai str. 56601 metallophosphoesterase NP_713346.1 3147588 R 189518 CDS NP_713347.2 294828256 1152509 complement(3148487..3149656) 1 NC_004342.2 ISlin1 transposase 3149656 1152509 LA_3167 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713347.2 3148487 R 189518 CDS NP_713348.2 294828257 1152510 complement(3149804..3150007) 1 NC_004342.2 cytoplasmic membrane protein 3150007 1152510 LA_3168 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713348.2 3149804 R 189518 CDS NP_713350.2 294828258 1152512 3150303..3152069 1 NC_004342.2 serine/threonine phosphatase 3152069 1152512 LA_3170 Leptospira interrogans serovar Lai str. 56601 serine/threonine phosphatase NP_713350.2 3150303 D 189518 CDS NP_713352.1 24215871 1152514 3153296..3154132 1 NC_004342.2 aldo/keto reductase 3154132 ara1 1152514 ara1 Leptospira interrogans serovar Lai str. 56601 aldo/keto reductase NP_713352.1 3153296 D 189518 CDS NP_713353.1 24215872 1152515 3154498..3155994 1 NC_004342.2 ABC transporter ATPase 3155994 uup 1152515 uup Leptospira interrogans serovar Lai str. 56601 ABC transporter ATPase NP_713353.1 3154498 D 189518 CDS NP_713355.1 24215874 1152517 3156933..3157484 1 NC_004342.2 hypothetical protein 3157484 1152517 LA_3175 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713355.1 3156933 D 189518 CDS NP_713357.1 24215876 1152519 3157827..3158213 1 NC_004342.2 hypothetical protein 3158213 1152519 LA_3176 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713357.1 3157827 D 189518 CDS NP_713359.1 24215878 1152521 3158871..3159746 1 NC_004342.2 hypothetical protein 3159746 1152521 LA_3179 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713359.1 3158871 D 189518 CDS NP_713360.2 294828259 1152522 3159898..3160194 1 NC_004342.2 hypothetical protein 3160194 1152522 LA_3180 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713360.2 3159898 D 189518 CDS NP_713361.2 294828260 1152523 3160979..3162604 1 NC_004342.2 hypothetical protein 3162604 1152523 LA_3181 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713361.2 3160979 D 189518 CDS NP_713362.1 24215881 1152524 3162604..3162888 1 NC_004342.2 CRISPR-associated protein Cas2 3162888 1152524 LA_3182 Leptospira interrogans serovar Lai str. 56601 CRISPR-associated protein Cas2 NP_713362.1 3162604 D 189518 CDS NP_713366.1 24215885 1152528 complement(3164497..3164874) 1 NC_004342.2 hypothetical protein 3164874 1152528 LA_3186 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713366.1 3164497 R 189518 CDS NP_713367.2 294828261 1152529 complement(3165489..3165713) 1 NC_004342.2 hypothetical protein 3165713 1152529 LA_3187 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713367.2 3165489 R 189518 CDS NP_713369.1 24215888 1152531 3166681..3167313 1 NC_004342.2 hypothetical protein 3167313 1152531 LA_3189 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713369.1 3166681 D 189518 CDS NP_713370.1 24215889 1152532 3167310..3169568 1 NC_004342.2 ATP-dependent RNA helicase 3169568 1152532 LA_3190 Leptospira interrogans serovar Lai str. 56601 ATP-dependent RNA helicase NP_713370.1 3167310 D 189518 CDS NP_713371.1 24215890 1152533 3169570..3171453 1 NC_004342.2 hypothetical protein 3171453 1152533 LA_3191 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713371.1 3169570 D 189518 CDS NP_713372.1 24215891 1152534 3171518..3172357 1 NC_004342.2 fruiting body developmental protein R 3172357 1152534 LA_3192 Leptospira interrogans serovar Lai str. 56601 fruiting body developmental protein R NP_713372.1 3171518 D 189518 CDS NP_713373.1 24215892 1152535 3172378..3173001 1 NC_004342.2 fruiting body developmental protein S 3173001 1152535 LA_3193 Leptospira interrogans serovar Lai str. 56601 fruiting body developmental protein S NP_713373.1 3172378 D 189518 CDS YP_003573336.1 294828262 9006944 complement(3173426..3173647) 1 NC_004342.2 hypothetical protein 3173647 9006944 LA_3193a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573336.1 3173426 R 189518 CDS NP_713375.2 294828263 1152537 3174108..3175277 1 NC_004342.2 ISlin1 transposase 3175277 1152537 LA_3195 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713375.2 3174108 D 189518 CDS NP_713376.1 24215895 1152538 3175489..3176007 1 NC_004342.2 hypothetical protein 3176007 1152538 LA_3196 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713376.1 3175489 D 189518 CDS NP_713377.1 24215896 1152539 3176357..3177898 1 NC_004342.2 type I restriction enzyme 3177898 hsdM 1152539 hsdM Leptospira interrogans serovar Lai str. 56601 type I restriction enzyme NP_713377.1 3176357 D 189518 CDS NP_713378.1 24215897 1152540 3177895..3179130 1 NC_004342.2 type I restriction enzyme EcoprrI specificity protein 3179130 hsdS 1152540 hsdS Leptospira interrogans serovar Lai str. 56601 type I restriction enzyme EcoprrI specificity protein NP_713378.1 3177895 D 189518 CDS NP_713379.1 24215898 1152541 3179127..3179684 1 NC_004342.2 anticodon nuclease 3179684 prrC 1152541 prrC Leptospira interrogans serovar Lai str. 56601 anticodon nuclease NP_713379.1 3179127 D 189518 CDS NP_713380.2 294828264 1152542 3179692..3180600 1 NC_004342.2 type I restriction enzyme 3180600 hsdR 1152542 hsdR Leptospira interrogans serovar Lai str. 56601 type I restriction enzyme NP_713380.2 3179692 D 189518 CDS YP_003573337.1 294828265 9006946 3185635..3187128 1 NC_004342.2 hypothetical protein 3187128 9006946 LA_3200b Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573337.1 3185635 D 189518 CDS NP_713381.2 294828266 1152543 3187456..3188208 1 NC_004342.2 hypothetical protein 3188208 1152543 LA_3201 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713381.2 3187456 D 189518 CDS NP_713383.1 24215902 1152545 3188348..3188539 1 NC_004342.2 hypothetical protein 3188539 1152545 LA_3203 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713383.1 3188348 D 189518 CDS NP_713384.1 24215903 1152546 complement(3188632..3189654) 1 NC_004342.2 Zn-dependent hydrolase 3189654 1152546 LA_3205 Leptospira interrogans serovar Lai str. 56601 Zn-dependent hydrolase NP_713384.1 3188632 R 189518 CDS NP_713386.2 294828267 1152548 complement(3189918..3190325) 1 NC_004342.2 two-component response regulator receiver protein 3190325 1152548 LA_3206 Leptospira interrogans serovar Lai str. 56601 two-component response regulator receiver protein NP_713386.2 3189918 R 189518 CDS NP_713387.1 24215906 1152549 complement(3190322..3193819) 1 NC_004342.2 histidine kinase sensor protein 3193819 1152549 LA_3207 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_713387.1 3190322 R 189518 CDS NP_713389.1 24215908 1152551 3194849..3195118 1 NC_004342.2 hypothetical protein 3195118 1152551 LA_3209 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713389.1 3194849 D 189518 CDS NP_713390.1 24215909 1152552 3195160..3195915 1 NC_004342.2 hypothetical protein 3195915 1152552 LA_3210 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713390.1 3195160 D 189518 CDS NP_713393.1 24215912 1152555 complement(3196358..3197032) 1 NC_004342.2 hypothetical protein 3197032 1152555 LA_3213 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713393.1 3196358 R 189518 CDS NP_713394.1 24215913 1152556 complement(3197074..3197577) 1 NC_004342.2 hypothetical protein 3197577 1152556 LA_3214 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713394.1 3197074 R 189518 CDS NP_713395.1 24215914 1152557 3198196..3198384 1 NC_004342.2 hypothetical protein 3198384 1152557 LA_3215 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713395.1 3198196 D 189518 CDS NP_713396.1 24215915 1152558 complement(3198793..3199752) 1 NC_004342.2 geranylgeranyl pyrophosphate synthase 3199752 ispA 1152558 ispA Leptospira interrogans serovar Lai str. 56601 geranylgeranyl pyrophosphate synthase NP_713396.1 3198793 R 189518 CDS NP_713397.2 294828268 1152559 complement(3199804..3200691) 1 NC_004342.2 hypothetical protein 3200691 1152559 LA_3217 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713397.2 3199804 R 189518 CDS NP_713399.2 294828269 1152561 complement(3201849..3202673) 1 NC_004342.2 hypothetical protein 3202673 1152561 LA_3219 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713399.2 3201849 R 189518 CDS NP_713400.2 294828270 1152562 complement(3202736..3202969) 1 NC_004342.2 hypothetical protein 3202969 1152562 LA_3220 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713400.2 3202736 R 189518 CDS NP_713404.2 294828271 1152566 3205819..3206217 1 NC_004342.2 hypothetical protein 3206217 1152566 LA_3224 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713404.2 3205819 D 189518 CDS NP_713407.2 294828272 1152569 complement(3206982..3207290) 1 NC_004342.2 hypothetical protein 3207290 1152569 LA_3227 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713407.2 3206982 R 189518 CDS NP_713410.2 294828273 1152572 complement(3207501..3208283) 1 NC_004342.2 hypothetical protein 3208283 1152572 LA_3230 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713410.2 3207501 R 189518 CDS NP_713411.1 24215930 1152573 3208959..3209363 1 NC_004342.2 hypothetical protein 3209363 1152573 LA_3231 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713411.1 3208959 D 189518 CDS NP_713413.1 24215932 1152575 complement(3210833..3211951) 1 NC_004342.2 hypothetical protein 3211951 1152575 LA_3233 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713413.1 3210833 R 189518 CDS NP_713414.1 24215933 1152576 complement(3211957..3213267) 1 NC_004342.2 guanylate cyclase 3213267 cyaA 1152576 cyaA Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_713414.1 3211957 R 189518 CDS NP_713415.1 24215934 1152577 complement(3213246..3213755) 1 NC_004342.2 guanylate cyclase 3213755 1152577 LA_3235 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_713415.1 3213246 R 189518 CDS NP_713419.1 24215938 1152581 3215136..3215450 1 NC_004342.2 hypothetical protein 3215450 1152581 LA_3239 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713419.1 3215136 D 189518 CDS NP_713420.2 294828274 1152582 3215607..3216992 1 NC_004342.2 hypothetical protein 3216992 lipL48 1152582 lipL48 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713420.2 3215607 D 189518 CDS NP_713421.1 24215940 1152583 3217066..3217809 1 NC_004342.2 hypothetical protein 3217809 1152583 LA_3241 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713421.1 3217066 D 189518 CDS NP_713422.2 294828275 1152584 3217806..3220766 1 NC_004342.2 TonB-dependent outer membrane receptor 3220766 1152584 LA_3242 Leptospira interrogans serovar Lai str. 56601 TonB-dependent outer membrane receptor NP_713422.2 3217806 D 189518 CDS NP_713423.1 24215942 1152585 3221984..3222520 1 NC_004342.2 hypothetical protein 3222520 1152585 LA_3243 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713423.1 3221984 D 189518 CDS NP_713424.1 24215943 1152586 3222884..3223696 1 NC_004342.2 biopolymer transport protein TolQ 3223696 tolQ 1152586 tolQ Leptospira interrogans serovar Lai str. 56601 biopolymer transport protein TolQ NP_713424.1 3222884 D 189518 CDS NP_713425.2 294828276 1152587 3223723..3224142 1 NC_004342.2 ExbD-like biopolymer transport protein 3224142 1152587 LA_3245 Leptospira interrogans serovar Lai str. 56601 ExbD-like biopolymer transport protein NP_713425.2 3223723 D 189518 CDS NP_713426.1 24215945 1152588 3224145..3224555 1 NC_004342.2 ExbD-like biopolymer transport protein 3224555 exbD 1152588 exbD Leptospira interrogans serovar Lai str. 56601 ExbD-like biopolymer transport protein NP_713426.1 3224145 D 189518 CDS NP_713427.1 24215946 1152589 3224559..3225149 1 NC_004342.2 TonB 3225149 1152589 LA_3247 Leptospira interrogans serovar Lai str. 56601 TonB NP_713427.1 3224559 D 189518 CDS NP_713429.1 24215948 1152591 3225815..3226561 1 NC_004342.2 ISlin1 transposase 3226561 1152591 LA_3249 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713429.1 3225815 D 189518 CDS NP_713430.2 294828277 1152592 3226567..3226926 1 NC_004342.2 ISlin1 transposase 3226926 1152592 LA_3250 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713430.2 3226567 D 189518 CDS NP_713432.1 24215951 1152594 complement(3227559..3228041) 1 NC_004342.2 ISlin1 transposase 3228041 1152594 LA_3252 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713432.1 3227559 R 189518 CDS NP_713433.2 294828278 1152595 complement(3228010..3228342) 1 NC_004342.2 ISlin1 transposase 3228342 1152595 LA_3253 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713433.2 3228010 R 189518 CDS NP_713435.1 24215954 1152597 complement(3229156..3229770) 1 NC_004342.2 hypothetical protein 3229770 1152597 LA_3255 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713435.1 3229156 R 189518 CDS NP_713438.1 24215957 1152600 complement(3231436..3234261) 1 NC_004342.2 TonB dependent receptor 3234261 1152600 LA_3258 Leptospira interrogans serovar Lai str. 56601 TonB dependent receptor NP_713438.1 3231436 R 189518 CDS NP_713440.1 24215959 1152602 complement(3235016..3235483) 1 NC_004342.2 hypothetical protein 3235483 1152602 LA_3260 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713440.1 3235016 R 189518 CDS NP_713442.1 24215961 1152604 complement(3235643..3236122) 1 NC_004342.2 hypothetical protein 3236122 1152604 LA_3262 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713442.1 3235643 R 189518 CDS NP_713443.1 24215962 1152605 complement(3236134..3237357) 1 NC_004342.2 hypothetical protein 3237357 1152605 LA_3263 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713443.1 3236134 R 189518 CDS NP_713444.1 24215963 1152606 complement(3237363..3237944) 1 NC_004342.2 hypothetical protein 3237944 1152606 LA_3264 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713444.1 3237363 R 189518 CDS NP_713445.1 24215964 1152607 complement(3237959..3238510) 1 NC_004342.2 hypothetical protein 3238510 1152607 LA_3265 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713445.1 3237959 R 189518 CDS NP_713446.2 294828279 1152608 complement(3238510..3239877) 1 NC_004342.2 Fe-S-cluster-containing hydrogenase 3239877 1152608 LA_3266 Leptospira interrogans serovar Lai str. 56601 Fe-S-cluster-containing hydrogenase NP_713446.2 3238510 R 189518 CDS NP_713447.1 24215966 1152609 complement(3239903..3243010) 1 NC_004342.2 molybdopterin oxidoreductase iron-sulfur binding subunit 3243010 1152609 LA_3267 Leptospira interrogans serovar Lai str. 56601 molybdopterin oxidoreductase iron-sulfur binding subunit NP_713447.1 3239903 R 189518 CDS NP_713448.1 24215967 1152610 complement(3243030..3243536) 1 NC_004342.2 hypothetical protein 3243536 1152610 LA_3268 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713448.1 3243030 R 189518 CDS NP_713450.1 24215969 1152612 3244035..3244643 1 NC_004342.2 hypothetical protein 3244643 1152612 LA_3270 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713450.1 3244035 D 189518 CDS NP_713451.1 24215970 1152613 3246739..3248649 1 NC_004342.2 hypothetical protein 3248649 1152613 LA_3271 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713451.1 3246739 D 189518 CDS NP_713457.2 294828280 1152619 complement(3250257..3251063) 1 NC_004342.2 hypothetical protein 3251063 1152619 LA_3277 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713457.2 3250257 R 189518 CDS NP_713456.2 294828281 1152618 complement(3251293..3252561) 1 NC_004342.2 hypothetical protein 3252561 1152618 LA_3276 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713456.2 3251293 R 189518 CDS NP_713455.1 24215974 1152617 3253222..3253440 1 NC_004342.2 hypothetical protein 3253440 1152617 LA_3275 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713455.1 3253222 D 189518 CDS NP_713454.1 24215973 1152616 3253430..3253873 1 NC_004342.2 hypothetical protein 3253873 1152616 LA_3274 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713454.1 3253430 D 189518 CDS NP_713453.2 294828282 1152615 complement(3254298..3255110) 1 NC_004342.2 hypothetical protein 3255110 1152615 LA_3273 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713453.2 3254298 R 189518 CDS NP_713461.2 294828283 1152623 complement(3255915..3256274) 1 NC_004342.2 ISlin1 transposase 3256274 1152623 LA_3281 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713461.2 3255915 R 189518 CDS NP_713462.2 294828284 1152624 complement(3256280..3256897) 1 NC_004342.2 ISlin1 transposase 3256897 1152624 LA_3282 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713462.2 3256280 R 189518 CDS NP_713464.1 24215983 1152626 complement(3257615..3258091) 1 NC_004342.2 TPR-repeat-containing protein 3258091 1152626 LA_3284 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_713464.1 3257615 R 189518 CDS NP_713465.1 24215984 1152627 complement(3258125..3260029) 1 NC_004342.2 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3260029 dxs 1152627 dxs Leptospira interrogans serovar Lai str. 56601 1-deoxy-D-xylulose-5-phosphate synthase NP_713465.1 3258125 R 189518 CDS NP_713466.1 24215985 1152628 complement(3260062..3262374) 1 NC_004342.2 adenylate cyclase 3262374 1152628 LA_3286 Leptospira interrogans serovar Lai str. 56601 adenylate cyclase NP_713466.1 3260062 R 189518 CDS NP_713467.1 24215986 1152629 3262443..3263003 1 NC_004342.2 hypothetical protein 3263003 1152629 LA_3287 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713467.1 3262443 D 189518 CDS NP_713468.1 24215987 1152630 complement(3263038..3263832) 1 NC_004342.2 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 3263832 trpA 1152630 trpA Leptospira interrogans serovar Lai str. 56601 tryptophan synthase subunit alpha NP_713468.1 3263038 R 189518 CDS NP_713469.1 24215988 1152631 complement(3263829..3265022) 1 NC_004342.2 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 3265022 trpB 1152631 trpB Leptospira interrogans serovar Lai str. 56601 tryptophan synthase subunit beta NP_713469.1 3263829 R 189518 CDS NP_713470.1 24215989 1152632 complement(3265025..3266755) 1 NC_004342.2 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 3266755 proS 1152632 proS Leptospira interrogans serovar Lai str. 56601 prolyl-tRNA synthetase NP_713470.1 3265025 R 189518 CDS NP_713471.1 24215990 1152633 complement(3266761..3268488) 1 NC_004342.2 zinc metalloprotease 3268488 1152633 LA_3291 Leptospira interrogans serovar Lai str. 56601 zinc metalloprotease NP_713471.1 3266761 R 189518 CDS NP_713472.2 294828285 1152634 complement(3268482..3269651) 1 NC_004342.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3269651 dxr 1152634 dxr Leptospira interrogans serovar Lai str. 56601 1-deoxy-D-xylulose 5-phosphate reductoisomerase NP_713472.2 3268482 R 189518 CDS NP_713473.1 24215992 1152635 complement(3269658..3270566) 1 NC_004342.2 CDP-diglyceride synthetase 3270566 cdsA 1152635 cdsA Leptospira interrogans serovar Lai str. 56601 CDP-diglyceride synthetase NP_713473.1 3269658 R 189518 CDS NP_713474.1 24215993 1152636 complement(3270559..3271284) 1 NC_004342.2 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 3271284 uppS 1152636 uppS Leptospira interrogans serovar Lai str. 56601 undecaprenyl pyrophosphate synthase NP_713474.1 3270559 R 189518 CDS NP_713475.1 24215994 1152637 complement(3271286..3271840) 1 NC_004342.2 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 3271840 frr 1152637 frr Leptospira interrogans serovar Lai str. 56601 ribosome recycling factor NP_713475.1 3271286 R 189518 CDS NP_713476.1 24215995 1152638 complement(3271830..3272576) 1 NC_004342.2 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 3272576 pyrH 1152638 pyrH Leptospira interrogans serovar Lai str. 56601 uridylate kinase NP_713476.1 3271830 R 189518 CDS NP_713477.1 24215996 1152639 complement(3272580..3273179) 1 NC_004342.2 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 3273179 tsf 1152639 tsf Leptospira interrogans serovar Lai str. 56601 elongation factor Ts NP_713477.1 3272580 R 189518 CDS NP_713478.2 294828286 1152640 complement(3273191..3274060) 1 NC_004342.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 3274060 rpsB 1152640 rpsB Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S2 NP_713478.2 3273191 R 189518 CDS NP_713480.1 24215999 1152642 complement(3274362..3274739) 1 NC_004342.2 cell shape determination protein 3274739 1152642 LA_3300 Leptospira interrogans serovar Lai str. 56601 cell shape determination protein NP_713480.1 3274362 R 189518 CDS NP_713481.1 24216000 1152643 complement(3274748..3274969) 1 NC_004342.2 hypothetical protein 3274969 1152643 LA_3301 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713481.1 3274748 R 189518 CDS NP_713482.1 24216001 1152644 complement(3274973..3275353) 1 NC_004342.2 phosphopantetheinyl transferase 3275353 acpS 1152644 acpS Leptospira interrogans serovar Lai str. 56601 phosphopantetheinyl transferase NP_713482.1 3274973 R 189518 CDS NP_713483.1 24216002 1152645 complement(3275350..3276405) 1 NC_004342.2 hypothetical protein 3276405 1152645 LA_3303 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713483.1 3275350 R 189518 CDS NP_713484.2 294828287 1152646 complement(3276408..3277229) 1 NC_004342.2 hypothetical protein 3277229 1152646 LA_3304 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713484.2 3276408 R 189518 CDS NP_713485.1 24216004 1152647 complement(3277242..3278054) 1 NC_004342.2 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 3278054 dapB 1152647 dapB Leptospira interrogans serovar Lai str. 56601 dihydrodipicolinate reductase NP_713485.1 3277242 R 189518 CDS NP_713486.1 24216005 1152648 complement(3278058..3278981) 1 NC_004342.2 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3278981 dapA 1152648 dapA Leptospira interrogans serovar Lai str. 56601 dihydrodipicolinate synthase NP_713486.1 3278058 R 189518 CDS NP_713487.2 294828288 1152649 3279037..3280083 1 NC_004342.2 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 3280083 1152649 LA_3307 Leptospira interrogans serovar Lai str. 56601 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase NP_713487.2 3279037 D 189518 CDS NP_713492.1 24216011 1152654 complement(3281936..3282361) 1 NC_004342.2 glyoxalase 3282361 1152654 LA_3312 Leptospira interrogans serovar Lai str. 56601 glyoxalase NP_713492.1 3281936 R 189518 CDS NP_713494.1 24216013 1152656 complement(3283602..3284504) 1 NC_004342.2 cell division inhibitor 3284504 1152656 LA_3314 Leptospira interrogans serovar Lai str. 56601 cell division inhibitor NP_713494.1 3283602 R 189518 CDS NP_713495.1 24216014 1152657 complement(3284669..3285415) 1 NC_004342.2 acetyltransferase 3285415 rimL 1152657 rimL Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_713495.1 3284669 R 189518 CDS NP_713496.1 24216015 1152658 complement(3285533..3286420) 1 NC_004342.2 hypothetical protein 3286420 1152658 LA_3316 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713496.1 3285533 R 189518 CDS NP_713497.1 24216016 1152659 complement(3286492..3287085) 1 NC_004342.2 dihydrofolate reductase-like protein 3287085 folA 1152659 folA Leptospira interrogans serovar Lai str. 56601 dihydrofolate reductase-like protein NP_713497.1 3286492 R 189518 CDS NP_713499.2 294828289 1152661 complement(3287763..3288173) 1 NC_004342.2 hypothetical protein 3288173 1152661 LA_3319 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713499.2 3287763 R 189518 CDS NP_713500.1 24216019 1152662 3288902..3290035 1 NC_004342.2 hypothetical protein 3290035 1152662 LA_3320 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713500.1 3288902 D 189518 CDS NP_713501.1 24216020 1152663 3290238..3291596 1 NC_004342.2 hypothetical protein 3291596 1152663 LA_3321 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713501.1 3290238 D 189518 CDS NP_713502.1 24216021 1152664 3291644..3292498 1 NC_004342.2 hypothetical protein 3292498 1152664 LA_3322 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713502.1 3291644 D 189518 CDS NP_713503.1 24216022 1152665 3292702..3293637 1 NC_004342.2 hypothetical protein 3293637 1152665 LA_3323 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713503.1 3292702 D 189518 CDS NP_713504.1 24216023 1152666 3293837..3294826 1 NC_004342.2 hypothetical protein 3294826 1152666 LA_3324 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713504.1 3293837 D 189518 CDS NP_713505.1 24216024 1152667 complement(3294894..3295745) 1 NC_004342.2 hypothetical protein 3295745 1152667 LA_3325 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713505.1 3294894 R 189518 CDS NP_713507.1 24216026 1152669 complement(3296198..3296821) 1 NC_004342.2 hypothetical protein 3296821 1152669 LA_3327 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713507.1 3296198 R 189518 CDS NP_713508.2 294828290 1152670 3297078..3297236 1 NC_004342.2 transposase 3297236 1152670 LA_3328 Leptospira interrogans serovar Lai str. 56601 transposase NP_713508.2 3297078 D 189518 CDS NP_713509.2 294828291 1152671 3297242..3298084 1 NC_004342.2 transposase 3298084 tra5 1152671 tra5 Leptospira interrogans serovar Lai str. 56601 transposase NP_713509.2 3297242 D 189518 CDS NP_713510.1 24216029 1152672 complement(3298169..3298843) 1 NC_004342.2 hypothetical protein 3298843 1152672 LA_3330 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713510.1 3298169 R 189518 CDS NP_713511.2 294828292 1152673 complement(3299203..3299664) 1 NC_004342.2 hypothetical protein 3299664 1152673 LA_3331 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713511.2 3299203 R 189518 CDS NP_713512.2 294828293 1152674 complement(3299889..3300119) 1 NC_004342.2 hypothetical protein 3300119 1152674 LA_3332 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713512.2 3299889 R 189518 CDS NP_713513.1 24216032 1152675 complement(3300659..3307579) 1 NC_004342.2 cytoplasmic membrane protein 3307579 1152675 LA_3333 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713513.1 3300659 R 189518 CDS NP_713514.1 24216033 1152676 3308046..3308930 1 NC_004342.2 hypothetical protein 3308930 1152676 LA_3334 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713514.1 3308046 D 189518 CDS NP_713516.2 294828294 1152678 3309322..3310623 1 NC_004342.2 hypothetical protein 3310623 1152678 LA_3336 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713516.2 3309322 D 189518 CDS NP_713517.1 24216036 1152679 3310632..3311255 1 NC_004342.2 hypothetical protein 3311255 1152679 LA_3337 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713517.1 3310632 D 189518 CDS NP_713519.1 24216038 1152681 3312005..3312382 1 NC_004342.2 hypothetical protein 3312382 1152681 LA_3338 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713519.1 3312005 D 189518 CDS NP_713520.2 294828295 1152682 3312297..3313079 1 NC_004342.2 hypothetical protein 3313079 1152682 LA_3340 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713520.2 3312297 D 189518 CDS NP_713522.1 24216041 1152684 complement(3314998..3315648) 1 NC_004342.2 hypothetical protein 3315648 1152684 LA_3342 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713522.1 3314998 R 189518 CDS NP_713524.1 24216043 1152686 complement(3316368..3316652) 1 NC_004342.2 hypothetical protein 3316652 1152686 LA_3344 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713524.1 3316368 R 189518 CDS NP_713526.2 294828296 1152688 3317863..3318639 1 NC_004342.2 hypothetical protein 3318639 1152688 LA_3345 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713526.2 3317863 D 189518 CDS NP_713529.1 24216048 1152691 3318957..3319352 1 NC_004342.2 cytochrome c-type biogenesis protein 3319352 ccmE 1152691 ccmE Leptospira interrogans serovar Lai str. 56601 cytochrome c-type biogenesis protein NP_713529.1 3318957 D 189518 CDS NP_713530.1 24216049 1152692 3319379..3321568 1 NC_004342.2 cytochrome c biogenesis protein 3321568 ccmF 1152692 ccmF Leptospira interrogans serovar Lai str. 56601 cytochrome c biogenesis protein NP_713530.1 3319379 D 189518 CDS NP_713531.1 24216050 1152693 3321565..3322164 1 NC_004342.2 cytochrome c-type biogenesis precursor 3322164 1152693 LA_3351 Leptospira interrogans serovar Lai str. 56601 cytochrome c-type biogenesis precursor NP_713531.1 3321565 D 189518 CDS NP_713532.1 24216051 1152694 3322164..3322562 1 NC_004342.2 hypothetical protein 3322562 1152694 LA_3352 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713532.1 3322164 D 189518 CDS NP_713533.1 24216052 1152695 3322529..3323242 1 NC_004342.2 hypothetical protein 3323242 1152695 LA_3353 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713533.1 3322529 D 189518 CDS NP_713534.2 294828297 1152696 complement(3323558..3324589) 1 NC_004342.2 Zn-dependent alcohol dehydrogenase 3324589 adhP 1152696 adhP Leptospira interrogans serovar Lai str. 56601 Zn-dependent alcohol dehydrogenase NP_713534.2 3323558 R 189518 CDS NP_713535.1 24216054 1152697 3324877..3325452 1 NC_004342.2 hypothetical protein 3325452 1152697 LA_3355 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713535.1 3324877 D 189518 CDS NP_713536.1 24216055 1152698 3326251..3326925 1 NC_004342.2 glutathione transferase 3326925 gst 1152698 gst Leptospira interrogans serovar Lai str. 56601 glutathione transferase NP_713536.1 3326251 D 189518 CDS NP_713537.1 24216056 1152699 complement(3326929..3329067) 1 NC_004342.2 histidine kinase sensor protein 3329067 1152699 LA_3357 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_713537.1 3326929 R 189518 CDS NP_713538.1 24216057 1152700 complement(3329775..3330317) 1 NC_004342.2 CopG-like transcriptional regulator 3330317 1152700 LA_3358 Leptospira interrogans serovar Lai str. 56601 CopG-like transcriptional regulator NP_713538.1 3329775 R 189518 CDS NP_713540.1 24216059 1152702 complement(3330971..3331705) 1 NC_004342.2 phosphoglycerate mutase-like protein 3331705 1152702 LA_3360 Leptospira interrogans serovar Lai str. 56601 phosphoglycerate mutase-like protein NP_713540.1 3330971 R 189518 CDS NP_713541.1 24216060 1152703 complement(3331710..3332105) 1 NC_004342.2 hypothetical protein 3332105 1152703 LA_3361 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713541.1 3331710 R 189518 CDS NP_713542.1 24216061 1152704 complement(3332095..3333135) 1 NC_004342.2 aminoglycoside phosphotransferase 3333135 1152704 LA_3362 Leptospira interrogans serovar Lai str. 56601 aminoglycoside phosphotransferase NP_713542.1 3332095 R 189518 CDS NP_713543.1 24216062 1152705 complement(3333156..3334331) 1 NC_004342.2 acyl-CoA dehydrogenase 3334331 caiA 1152705 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_713543.1 3333156 R 189518 CDS NP_713545.1 24216064 1152707 3335547..3336344 1 NC_004342.2 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 3336344 thiM 1152707 thiM Leptospira interrogans serovar Lai str. 56601 hydroxyethylthiazole kinase NP_713545.1 3335547 D 189518 CDS NP_713546.2 294828298 1152708 3336709..3337440 1 NC_004342.2 enoyl-CoA hydratase 3337440 caiD 1152708 caiD Leptospira interrogans serovar Lai str. 56601 enoyl-CoA hydratase NP_713546.2 3336709 D 189518 CDS NP_713547.1 24216066 1152709 complement(3337537..3337968) 1 NC_004342.2 hypothetical protein 3337968 1152709 LA_3367 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713547.1 3337537 R 189518 CDS NP_713548.1 24216067 1152710 complement(3338034..3338258) 1 NC_004342.2 hypothetical protein 3338258 1152710 LA_3368 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713548.1 3338034 R 189518 CDS NP_713549.1 24216068 1152711 complement(3338260..3338523) 1 NC_004342.2 hypothetical protein 3338523 1152711 LA_3369 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713549.1 3338260 R 189518 CDS NP_713550.1 24216069 1152712 complement(3340068..3341438) 1 NC_004342.2 surface antigen OrfC lipoprotein 3341438 1152712 LA_3370 Leptospira interrogans serovar Lai str. 56601 surface antigen OrfC lipoprotein NP_713550.1 3340068 R 189518 CDS NP_713551.2 294828299 1152713 complement(3341449..3342525) 1 NC_004342.2 glucans biosynthesis protein 3342525 mdoC 1152713 mdoC Leptospira interrogans serovar Lai str. 56601 glucans biosynthesis protein NP_713551.2 3341449 R 189518 CDS NP_713552.1 24216071 1152714 complement(3342618..3343250) 1 NC_004342.2 cAMP-binding protein 3343250 crp 1152714 crp Leptospira interrogans serovar Lai str. 56601 cAMP-binding protein NP_713552.1 3342618 R 189518 CDS NP_713557.2 294828300 1152719 3345312..3345563 1 NC_004342.2 hypothetical protein 3345563 1152719 LA_3377 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713557.2 3345312 D 189518 CDS NP_713558.2 294828301 1152720 complement(3345715..3348495) 1 NC_004342.2 contains N-terminal domain of unknown function fused to transcription elongation factor; GreA is necessary for efficient RNA polymerization through arresting sites; cleaves the nascent transcript and allows resumption of transcription elongation; transcript cleavage factor/unknown domain fusion protein 3348495 1152720 LA_3378 Leptospira interrogans serovar Lai str. 56601 transcript cleavage factor/unknown domain fusion protein NP_713558.2 3345715 R 189518 CDS NP_713559.2 294828302 1152721 complement(3348692..3349639) 1 NC_004342.2 flagellar filament sheath protein 3349639 1152721 LA_3379 Leptospira interrogans serovar Lai str. 56601 flagellar filament sheath protein NP_713559.2 3348692 R 189518 CDS NP_713560.1 24216079 1152722 complement(3349663..3350382) 1 NC_004342.2 endoflagellar filament sheath protein 3350382 1152722 LA_3380 Leptospira interrogans serovar Lai str. 56601 endoflagellar filament sheath protein NP_713560.1 3349663 R 189518 CDS NP_713563.2 294828303 1152725 complement(3351379..3351522) 1 NC_004342.2 hypothetical protein 3351522 1152725 LA_3383 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713563.2 3351379 R 189518 CDS NP_713565.1 24216084 1152727 complement(3352108..3352521) 1 NC_004342.2 hypothetical protein 3352521 1152727 LA_3385 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713565.1 3352108 R 189518 CDS NP_713567.2 294828304 1152729 3354302..3354547 1 NC_004342.2 hypothetical protein 3354547 1152729 LA_3387 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713567.2 3354302 D 189518 CDS NP_713568.1 24216087 1152730 3354783..3356678 1 NC_004342.2 hypothetical protein 3356678 1152730 LA_3388 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713568.1 3354783 D 189518 CDS YP_003573340.1 294828305 9006951 complement(3356793..3356915) 1 NC_004342.2 hypothetical protein 3356915 9006951 LA_3388a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573340.1 3356793 R 189518 CDS NP_713570.1 24216089 1152732 complement(3358271..3359101) 1 NC_004342.2 hypothetical protein 3359101 1152732 LA_3390 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713570.1 3358271 R 189518 CDS NP_713571.2 294828306 1152733 complement(3359105..3360205) 1 NC_004342.2 hypothetical protein 3360205 1152733 LA_3392 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713571.2 3359105 R 189518 CDS NP_713574.2 294828307 1152736 3361783..3362850 1 NC_004342.2 hypothetical protein 3362850 1152736 LA_3394 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713574.2 3361783 D 189518 CDS NP_713576.2 294828308 1152738 complement(3363222..3364556) 1 NC_004342.2 hypothetical protein 3364556 1152738 LA_3396 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713576.2 3363222 R 189518 CDS NP_713577.2 294828309 1152739 complement(3364631..3365410) 1 NC_004342.2 hypothetical protein 3365410 1152739 LA_3397 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713577.2 3364631 R 189518 CDS NP_713578.1 24216097 1152740 complement(3365636..3366313) 1 NC_004342.2 O-methyltransferase 3366313 1152740 LA_3398 Leptospira interrogans serovar Lai str. 56601 O-methyltransferase NP_713578.1 3365636 R 189518 CDS NP_713579.1 24216098 1152741 complement(3366310..3367137) 1 NC_004342.2 metallo-beta-lactamase 3367137 1152741 LA_3399 Leptospira interrogans serovar Lai str. 56601 metallo-beta-lactamase NP_713579.1 3366310 R 189518 CDS NP_713580.1 24216099 1152742 complement(3367137..3368810) 1 NC_004342.2 Zn-dependent peptidase 3368810 1152742 LA_3400 Leptospira interrogans serovar Lai str. 56601 Zn-dependent peptidase NP_713580.1 3367137 R 189518 CDS NP_713581.1 24216100 1152743 complement(3368812..3370440) 1 NC_004342.2 Zn-dependent peptidase 3370440 pqqL 1152743 pqqL Leptospira interrogans serovar Lai str. 56601 Zn-dependent peptidase NP_713581.1 3368812 R 189518 CDS NP_713582.1 24216101 1152744 3370469..3371251 1 NC_004342.2 hypothetical protein 3371251 1152744 LA_3402 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713582.1 3370469 D 189518 CDS NP_713583.1 24216102 1152745 3371248..3371682 1 NC_004342.2 hypothetical protein 3371682 1152745 LA_3403 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713583.1 3371248 D 189518 CDS NP_713585.2 294828310 1152747 complement(3372645..3373034) 1 NC_004342.2 hypothetical protein 3373034 1152747 LA_3405 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713585.2 3372645 R 189518 CDS NP_713586.1 24216105 1152748 complement(3373325..3373816) 1 NC_004342.2 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 3373816 1152748 LA_3406 Leptospira interrogans serovar Lai str. 56601 nucleotide-binding protein NP_713586.1 3373325 R 189518 CDS NP_713587.1 24216106 1152749 complement(3373813..3376746) 1 NC_004342.2 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 3376746 alaS 1152749 alaS Leptospira interrogans serovar Lai str. 56601 alanyl-tRNA synthetase NP_713587.1 3373813 R 189518 CDS NP_713588.2 294828311 1152750 complement(3376830..3377228) 1 NC_004342.2 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3377228 rpsI 1152750 rpsI Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S9 NP_713588.2 3376830 R 189518 CDS NP_713589.1 24216108 1152751 complement(3377239..3377688) 1 NC_004342.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3377688 rplM 1152751 rplM Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L13 NP_713589.1 3377239 R 189518 CDS NP_713590.1 24216109 1152752 complement(3378675..3379304) 1 NC_004342.2 hypothetical protein 3379304 1152752 LA_3410 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713590.1 3378675 R 189518 CDS NP_713592.1 24216111 1152754 3379346..3380269 1 NC_004342.2 thiamine monophosphate kinase 3380269 thiL 1152754 thiL Leptospira interrogans serovar Lai str. 56601 thiamine monophosphate kinase NP_713592.1 3379346 D 189518 CDS NP_713594.1 24216113 1152756 3381170..3381352 1 NC_004342.2 hypothetical protein 3381352 1152756 LA_3414 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713594.1 3381170 D 189518 CDS NP_713595.2 294828312 1152757 3381788..3382012 1 NC_004342.2 hypothetical protein 3382012 1152757 LA_3415 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713595.2 3381788 D 189518 CDS NP_713596.1 24216115 1152758 complement(3382130..3382603) 1 NC_004342.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3382603 rpsG 1152758 rpsG Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S7 NP_713596.1 3382130 R 189518 CDS NP_713597.1 24216116 1152759 complement(3382621..3382995) 1 NC_004342.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3382995 rpsL 1152759 rpsL Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S12 NP_713597.1 3382621 R 189518 CDS NP_713599.1 24216118 1152761 complement(3383393..3387607) 1 NC_004342.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 3387607 rpoC 1152761 rpoC Leptospira interrogans serovar Lai str. 56601 DNA-directed RNA polymerase subunit beta' NP_713599.1 3383393 R 189518 CDS NP_713600.1 24216119 1152762 complement(3387611..3391291) 1 NC_004342.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 3391291 rpoB 1152762 rpoB Leptospira interrogans serovar Lai str. 56601 DNA-directed RNA polymerase subunit beta NP_713600.1 3387611 R 189518 CDS NP_713601.1 24216120 1152763 complement(3391514..3391897) 1 NC_004342.2 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 3391897 rplL 1152763 rplL Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L7/L12 NP_713601.1 3391514 R 189518 CDS NP_713602.1 24216121 1152764 complement(3391947..3392480) 1 NC_004342.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 3392480 rplJ 1152764 rplJ Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L10 NP_713602.1 3391947 R 189518 CDS NP_713603.1 24216122 1152765 complement(3392508..3393200) 1 NC_004342.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 3393200 rplA 1152765 rplA Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L1 NP_713603.1 3392508 R 189518 CDS NP_713604.1 24216123 1152766 complement(3393207..3393635) 1 NC_004342.2 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 3393635 rplK 1152766 rplK Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L11 NP_713604.1 3393207 R 189518 CDS NP_713605.1 24216124 1152767 complement(3393662..3394207) 1 NC_004342.2 transcription antiterminator 3394207 nusG 1152767 nusG Leptospira interrogans serovar Lai str. 56601 transcription antiterminator NP_713605.1 3393662 R 189518 CDS NP_713606.1 24216125 1152768 complement(3394235..3394423) 1 NC_004342.2 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 3394423 secE 1152768 secE Leptospira interrogans serovar Lai str. 56601 preprotein translocase subunit SecE NP_713606.1 3394235 R 189518 CDS YP_003573341.1 294828313 9006954 3394946..3395170 1 NC_004342.2 hypothetical protein 3395170 9006954 LA_3426a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573341.1 3394946 D 189518 CDS NP_713610.1 24216129 1152772 3395485..3395655 1 NC_004342.2 ISlin1 transposase 3395655 1152772 LA_3430 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713610.1 3395485 D 189518 CDS NP_713612.2 294828314 1152774 complement(3397879..3399456) 1 NC_004342.2 hypothetical protein 3399456 1152774 LA_3432 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713612.2 3397879 R 189518 CDS NP_713613.2 294828315 1152775 complement(3399500..3400285) 1 NC_004342.2 hypothetical protein 3400285 1152775 LA_3433 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713613.2 3399500 R 189518 CDS NP_713614.1 24216133 1152776 complement(3400266..3401357) 1 NC_004342.2 N-acetylmuramoyl-L-alanine amidase 3401357 amiC 1152776 amiC Leptospira interrogans serovar Lai str. 56601 N-acetylmuramoyl-L-alanine amidase NP_713614.1 3400266 R 189518 CDS NP_713615.1 24216134 1152777 complement(3401324..3402946) 1 NC_004342.2 DEAD/DEAH box helicase 3402946 srmB 1152777 srmB Leptospira interrogans serovar Lai str. 56601 DEAD/DEAH box helicase NP_713615.1 3401324 R 189518 CDS NP_713616.1 24216135 1152778 complement(3402943..3403746) 1 NC_004342.2 3-demethylubiquinone-9 3-methyltransferase 3403746 1152778 LA_3436 Leptospira interrogans serovar Lai str. 56601 3-demethylubiquinone-9 3-methyltransferase NP_713616.1 3402943 R 189518 CDS NP_713617.1 24216136 1152779 3403865..3404332 1 NC_004342.2 bifunctional translation initiation inhibitor/endoribonuclease L-PSP 3404332 tdcF 1152779 tdcF Leptospira interrogans serovar Lai str. 56601 bifunctional translation initiation inhibitor/endoribonuclease L-PSP NP_713617.1 3403865 D 189518 CDS NP_713618.2 294828316 1152780 3404322..3404828 1 NC_004342.2 hypothetical protein 3404828 1152780 LA_3438 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713618.2 3404322 D 189518 CDS NP_713620.1 24216139 1152782 complement(3405527..3406321) 1 NC_004342.2 hypothetical protein 3406321 1152782 LA_3440 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713620.1 3405527 R 189518 CDS NP_713621.1 24216140 1152783 complement(3407473..3408960) 1 NC_004342.2 leucyl aminopeptidase 3408960 pepA 1152783 pepA Leptospira interrogans serovar Lai str. 56601 leucyl aminopeptidase NP_713621.1 3407473 R 189518 CDS NP_713622.1 24216141 1152784 complement(3408957..3409436) 1 NC_004342.2 peroxiredoxin 3409436 bcp 1152784 bcp Leptospira interrogans serovar Lai str. 56601 peroxiredoxin NP_713622.1 3408957 R 189518 CDS NP_713624.1 24216143 1152786 complement(3410474..3411733) 1 NC_004342.2 penicillin binding protein 3411733 1152786 LA_3444 Leptospira interrogans serovar Lai str. 56601 penicillin binding protein NP_713624.1 3410474 R 189518 CDS NP_713627.2 294828317 1152789 3411871..3412350 1 NC_004342.2 hypothetical protein 3412350 1152789 LA_3446 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713627.2 3411871 D 189518 CDS NP_713628.2 294828318 1152790 complement(3413075..3413710) 1 NC_004342.2 hypothetical protein 3413710 1152790 LA_3448 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713628.2 3413075 R 189518 CDS NP_713629.2 294828319 1152791 3413742..3414698 1 NC_004342.2 riboflavin biosynthesis protein 3414698 ribF 1152791 ribF Leptospira interrogans serovar Lai str. 56601 riboflavin biosynthesis protein NP_713629.2 3413742 D 189518 CDS NP_713630.1 24216149 1152792 3414794..3416590 1 NC_004342.2 regulatory protein 3416590 1152792 LA_3450 Leptospira interrogans serovar Lai str. 56601 regulatory protein NP_713630.1 3414794 D 189518 CDS NP_713631.1 24216150 1152793 3416594..3418369 1 NC_004342.2 serine phosphatase RsbU 3418369 rsbU 1152793 rsbU Leptospira interrogans serovar Lai str. 56601 serine phosphatase RsbU NP_713631.1 3416594 D 189518 CDS NP_713633.1 24216152 1152795 complement(3419020..3419976) 1 NC_004342.2 hypothetical protein 3419976 1152795 LA_3453 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713633.1 3419020 R 189518 CDS NP_713634.1 24216153 1152796 complement(3419994..3421913) 1 NC_004342.2 involved in flagellin assembly; flagellar hook-associated protein FliD 3421913 fliD 1152796 fliD Leptospira interrogans serovar Lai str. 56601 flagellar hook-associated protein FliD NP_713634.1 3419994 R 189518 CDS NP_713635.1 24216154 1152797 3422490..3423206 1 NC_004342.2 glycerol uptake facilitator protein 3423206 glpF 1152797 glpF Leptospira interrogans serovar Lai str. 56601 glycerol uptake facilitator protein NP_713635.1 3422490 D 189518 CDS NP_713636.1 24216155 1152798 3424328..3425521 1 NC_004342.2 metalloendopeptidase 3425521 1152798 LA_3456 Leptospira interrogans serovar Lai str. 56601 metalloendopeptidase NP_713636.1 3424328 D 189518 CDS NP_713638.1 24216157 1152800 complement(3426339..3426581) 1 NC_004342.2 hypothetical protein 3426581 1152800 LA_3458 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713638.1 3426339 R 189518 CDS NP_713640.1 24216159 1152802 3426835..3428973 1 NC_004342.2 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3428973 ppk 1152802 ppk Leptospira interrogans serovar Lai str. 56601 polyphosphate kinase NP_713640.1 3426835 D 189518 CDS NP_713641.2 294828320 1152803 3428984..3430408 1 NC_004342.2 FAD/FMN-containing dehydrogenase 3430408 glcD 1152803 glcD Leptospira interrogans serovar Lai str. 56601 FAD/FMN-containing dehydrogenase NP_713641.2 3428984 D 189518 CDS NP_713642.1 24216161 1152804 3430408..3431991 1 NC_004342.2 carbon-nitrogen hydrolase 3431991 1152804 LA_3462 Leptospira interrogans serovar Lai str. 56601 carbon-nitrogen hydrolase NP_713642.1 3430408 D 189518 CDS NP_713643.1 24216162 1152805 3431973..3432320 1 NC_004342.2 hypothetical protein 3432320 1152805 LA_3463 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713643.1 3431973 D 189518 CDS NP_713646.1 24216165 1152808 complement(3433594..3435996) 1 NC_004342.2 thermolysin 3435996 1152808 LA_3466 Leptospira interrogans serovar Lai str. 56601 thermolysin NP_713646.1 3433594 R 189518 CDS NP_713648.1 24216167 1152810 3437409..3439886 1 NC_004342.2 outer membrane receptor for Fe3+-dicitrate/TonB-dependent receptor 3439886 1152810 LA_3468 Leptospira interrogans serovar Lai str. 56601 outer membrane receptor for Fe3+-dicitrate/TonB-dependent receptor NP_713648.1 3437409 D 189518 CDS YP_003573342.1 294828321 9006955 3439966..3440115 1 NC_004342.2 hypothetical protein 3440115 9006955 LA_3468a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573342.1 3439966 D 189518 CDS NP_713649.1 24216168 1152811 3440317..3441639 1 NC_004342.2 hypothetical protein 3441639 irpA 1152811 irpA Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713649.1 3440317 D 189518 CDS NP_713650.1 24216169 1152816 3441671..3443182 1 NC_004342.2 thiol oxidoreductase 3443182 1152816 LA_3470 Leptospira interrogans serovar Lai str. 56601 thiol oxidoreductase NP_713650.1 3441671 D 189518 CDS NP_713651.1 24216170 1152813 3443179..3444393 1 NC_004342.2 hypothetical protein 3444393 1152813 LA_3471 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713651.1 3443179 D 189518 CDS NP_713652.1 24216171 1152814 complement(3445042..3445404) 1 NC_004342.2 hypothetical protein 3445404 1152814 LA_3472 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713652.1 3445042 R 189518 CDS YP_003573343.1 294828322 9006956 complement(3446871..3447503) 1 NC_004342.2 hypothetical protein 3447503 9006956 LA_3472a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573343.1 3446871 R 189518 CDS NP_713653.2 294828323 1152815 complement(3447503..3448222) 1 NC_004342.2 hypothetical protein 3448222 1152815 LA_3473 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713653.2 3447503 R 189518 CDS NP_713654.1 24216173 9006957 complement(3448219..3449646) 1 NC_004342.2 hypothetical protein 3449646 9006957 LA_3474 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713654.1 3448219 R 189518 CDS NP_713655.1 24216174 1152817 complement(3449666..3450208) 1 NC_004342.2 hypothetical protein 3450208 1152817 LA_3475 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713655.1 3449666 R 189518 CDS NP_713656.1 24216175 1152818 complement(3450225..3450764) 1 NC_004342.2 hypothetical protein 3450764 1152818 LA_3476 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713656.1 3450225 R 189518 CDS NP_713657.1 24216176 1152819 complement(3450798..3451340) 1 NC_004342.2 hypothetical protein 3451340 1152819 LA_3477 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713657.1 3450798 R 189518 CDS NP_713658.2 294828324 1152820 complement(3451395..3452063) 1 NC_004342.2 hypothetical protein 3452063 1152820 LA_3478 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713658.2 3451395 R 189518 CDS NP_713659.1 24216178 1152821 complement(3452075..3452800) 1 NC_004342.2 hypothetical protein 3452800 1152821 LA_3479 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713659.1 3452075 R 189518 CDS NP_713660.1 24216179 1152822 complement(3452791..3453117) 1 NC_004342.2 hypothetical protein 3453117 1152822 LA_3480 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713660.1 3452791 R 189518 CDS NP_713661.2 294828325 1152823 3453973..3454188 1 NC_004342.2 IS1501 transposase 3454188 1152823 LA_3481 Leptospira interrogans serovar Lai str. 56601 IS1501 transposase NP_713661.2 3453973 D 189518 CDS NP_713662.2 294828326 1152824 3454309..3454698 1 NC_004342.2 IS1501 transposase 3454698 1152824 LA_3482 Leptospira interrogans serovar Lai str. 56601 IS1501 transposase NP_713662.2 3454309 D 189518 CDS NP_713663.1 24216182 1152825 3454695..3455108 1 NC_004342.2 IS1501 transposase 3455108 tra5 1152825 tra5 Leptospira interrogans serovar Lai str. 56601 IS1501 transposase NP_713663.1 3454695 D 189518 CDS NP_713664.2 294828327 1152826 complement(3455692..3456459) 1 NC_004342.2 short chain dehydrogenase 3456459 fabG 1152826 fabG Leptospira interrogans serovar Lai str. 56601 short chain dehydrogenase NP_713664.2 3455692 R 189518 CDS NP_713665.1 24216184 1152827 3456622..3457329 1 NC_004342.2 esterase 3457329 1152827 LA_3485 Leptospira interrogans serovar Lai str. 56601 esterase NP_713665.1 3456622 D 189518 CDS NP_713666.1 24216185 1152828 3457326..3458000 1 NC_004342.2 hypothetical protein 3458000 1152828 LA_3486 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713666.1 3457326 D 189518 CDS NP_713669.1 24216188 1152831 3459316..3460146 1 NC_004342.2 flagellar basal body rod protein FlgC 3460146 1152831 LA_3489 Leptospira interrogans serovar Lai str. 56601 flagellar basal body rod protein FlgC NP_713669.1 3459316 D 189518 CDS NP_713670.1 24216189 1152832 3460643..3462562 1 NC_004342.2 hypothetical protein 3462562 1152832 LA_3490 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713670.1 3460643 D 189518 CDS NP_713671.2 294828328 1152833 3462986..3463393 1 NC_004342.2 hypothetical protein 3463393 1152833 LA_3491 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713671.2 3462986 D 189518 CDS NP_713672.2 294828329 1152834 3464227..3465036 1 NC_004342.2 hypothetical protein 3465036 1152834 LA_3492 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713672.2 3464227 D 189518 CDS NP_713674.2 294828330 1152836 complement(3465981..3466445) 1 NC_004342.2 hypothetical protein 3466445 1152836 LA_3494 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713674.2 3465981 R 189518 CDS NP_713677.1 24216196 1152839 complement(3467202..3469424) 1 NC_004342.2 hypothetical protein 3469424 1152839 LA_3497 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713677.1 3467202 R 189518 CDS NP_713678.1 24216197 1152840 complement(3469566..3470282) 1 NC_004342.2 phosphate ABC transporter regulatory protein 3470282 1152840 LA_3498 Leptospira interrogans serovar Lai str. 56601 phosphate ABC transporter regulatory protein NP_713678.1 3469566 R 189518 CDS NP_713679.1 24216198 1152841 complement(3470913..3471341) 1 NC_004342.2 hypothetical protein 3471341 1152841 LA_3499 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713679.1 3470913 R 189518 CDS NP_713680.1 24216199 1152842 complement(3471735..3472313) 1 NC_004342.2 hypothetical protein 3472313 1152842 LA_3500 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713680.1 3471735 R 189518 CDS NP_713681.1 24216200 1152843 3472940..3474211 1 NC_004342.2 hypothetical protein 3474211 1152843 LA_3501 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713681.1 3472940 D 189518 CDS YP_003573344.1 294828331 9006958 3474869..3475222 1 NC_004342.2 hypothetical protein 3475222 9006958 LA_3501a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573344.1 3474869 D 189518 CDS YP_003573345.1 294828332 9006959 3475229..3475618 1 NC_004342.2 hypothetical protein 3475618 9006959 LA_3501b Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573345.1 3475229 D 189518 CDS NP_713684.2 294828333 1152846 3475615..3476016 1 NC_004342.2 hypothetical protein 3476016 1152846 LA_3504 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713684.2 3475615 D 189518 CDS NP_713685.1 24216204 1152847 3476023..3476832 1 NC_004342.2 hypothetical protein 3476832 1152847 LA_3505 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713685.1 3476023 D 189518 CDS NP_713686.2 294828334 1152848 complement(3477048..3478694) 1 NC_004342.2 methyl-accepting chemotaxis transducer transmembrane protein 3478694 1152848 LA_3506 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis transducer transmembrane protein NP_713686.2 3477048 R 189518 CDS NP_713687.1 24216206 1152849 complement(3478794..3479153) 1 NC_004342.2 cytochrome c 3479153 1152849 LA_3507 Leptospira interrogans serovar Lai str. 56601 cytochrome c NP_713687.1 3478794 R 189518 CDS NP_713688.1 24216207 1152850 complement(3479153..3479470) 1 NC_004342.2 methylamine utilization protein 3479470 petE 1152850 petE Leptospira interrogans serovar Lai str. 56601 methylamine utilization protein NP_713688.1 3479153 R 189518 CDS NP_713689.2 294828335 1152851 complement(3479503..3480522) 1 NC_004342.2 cytochrome c peroxidase 3480522 mauG 1152851 mauG Leptospira interrogans serovar Lai str. 56601 cytochrome c peroxidase NP_713689.2 3479503 R 189518 CDS NP_713691.1 24216210 1152853 complement(3481866..3482525) 1 NC_004342.2 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 3482525 purL 1152853 purL Leptospira interrogans serovar Lai str. 56601 phosphoribosylformylglycinamidine synthase I NP_713691.1 3481866 R 189518 CDS NP_713692.1 24216211 1152854 complement(3482522..3482770) 1 NC_004342.2 phosphoribosylformylglycinamidine synthase 3482770 purS 1152854 purS Leptospira interrogans serovar Lai str. 56601 phosphoribosylformylglycinamidine synthase NP_713692.1 3482522 R 189518 CDS NP_713693.1 24216212 1152855 complement(3482746..3483603) 1 NC_004342.2 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 3483603 purC 1152855 purC Leptospira interrogans serovar Lai str. 56601 phosphoribosylaminoimidazole-succinocarboxamide synthase NP_713693.1 3482746 R 189518 CDS NP_713694.1 24216213 1152856 complement(3483600..3484733) 1 NC_004342.2 serine/threonine phosphatase 3484733 1152856 LA_3514 Leptospira interrogans serovar Lai str. 56601 serine/threonine phosphatase NP_713694.1 3483600 R 189518 CDS NP_713695.2 294828336 1152857 complement(3484740..3485432) 1 NC_004342.2 heme exporter protein C 3485432 1152857 LA_3515 Leptospira interrogans serovar Lai str. 56601 heme exporter protein C NP_713695.2 3484740 R 189518 CDS NP_713696.1 24216215 1152858 complement(3485489..3486160) 1 NC_004342.2 heme exporter protein B 3486160 1152858 LA_3516 Leptospira interrogans serovar Lai str. 56601 heme exporter protein B NP_713696.1 3485489 R 189518 CDS NP_713697.1 24216216 1152859 complement(3486132..3486854) 1 NC_004342.2 ABC transporter ATP-binding protein 3486854 ccmA 1152859 ccmA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_713697.1 3486132 R 189518 CDS YP_003573346.1 294828337 9006960 3487041..3487613 1 NC_004342.2 hypothetical protein 3487613 9006960 LA_3517a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573346.1 3487041 D 189518 CDS NP_713701.1 24216220 1152863 3488007..3489143 1 NC_004342.2 TPR-repeat-containing protein 3489143 1152863 LA_3521 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_713701.1 3488007 D 189518 CDS NP_713702.1 24216221 1152864 3489140..3489829 1 NC_004342.2 hypothetical protein 3489829 1152864 LA_3522 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713702.1 3489140 D 189518 CDS NP_713703.1 24216222 1152865 complement(3489830..3490594) 1 NC_004342.2 ABC transporter ATP-binding protein 3490594 1152865 LA_3523 Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_713703.1 3489830 R 189518 CDS NP_713704.1 24216223 1152866 3491511..3492086 1 NC_004342.2 hypothetical protein 3492086 1152866 LA_3524 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713704.1 3491511 D 189518 CDS NP_713707.1 24216226 1152869 complement(3492766..3493053) 1 NC_004342.2 hypothetical protein 3493053 1152869 LA_3527 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713707.1 3492766 R 189518 CDS NP_713708.1 24216227 1152870 complement(3493059..3493964) 1 NC_004342.2 mrr restriction system protein 3493964 mrr 1152870 mrr Leptospira interrogans serovar Lai str. 56601 mrr restriction system protein NP_713708.1 3493059 R 189518 CDS NP_713709.2 294828338 1152871 complement(3494089..3494505) 1 NC_004342.2 thioesterase-like protein 3494505 1152871 LA_3529 Leptospira interrogans serovar Lai str. 56601 thioesterase-like protein NP_713709.2 3494089 R 189518 CDS NP_713711.1 24216230 1152873 3496098..3496478 1 NC_004342.2 transcriptional regulator 3496478 arsR 1152873 arsR Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_713711.1 3496098 D 189518 CDS NP_713712.1 24216231 1152874 3496459..3496851 1 NC_004342.2 hypothetical protein 3496851 1152874 LA_3532 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713712.1 3496459 D 189518 CDS NP_713713.1 24216232 1152875 3496943..3497431 1 NC_004342.2 hypothetical protein 3497431 1152875 LA_3533 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713713.1 3496943 D 189518 CDS NP_713714.2 294828339 1152876 3497714..3498190 1 NC_004342.2 hypothetical protein 3498190 1152876 LA_3534 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713714.2 3497714 D 189518 CDS NP_713715.1 24216234 1152877 3498212..3498760 1 NC_004342.2 hypothetical protein 3498760 1152877 LA_3535 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713715.1 3498212 D 189518 CDS NP_713716.2 294828340 1152878 3499030..3499491 1 NC_004342.2 activator of Hsp90 ATPase 1 family protein 3499491 1152878 LA_3536 Leptospira interrogans serovar Lai str. 56601 activator of Hsp90 ATPase 1 family protein NP_713716.2 3499030 D 189518 CDS NP_713717.2 294828341 1152879 3500166..3500795 1 NC_004342.2 hypothetical protein 3500795 1152879 LA_3537 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713717.2 3500166 D 189518 CDS NP_713718.1 24216237 1152880 3500808..3501356 1 NC_004342.2 hypothetical protein 3501356 1152880 LA_3538 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713718.1 3500808 D 189518 CDS NP_713719.1 24216238 1152881 3501368..3502891 1 NC_004342.2 proton antiporter efflux pump 3502891 1152881 LA_3539 Leptospira interrogans serovar Lai str. 56601 proton antiporter efflux pump NP_713719.1 3501368 D 189518 CDS NP_713720.2 294828342 1152882 complement(3503233..3504810) 1 NC_004342.2 sphingomyelinase C precursor 3504810 1152882 LA_3540 Leptospira interrogans serovar Lai str. 56601 sphingomyelinase C precursor NP_713720.2 3503233 R 189518 CDS NP_713722.2 294828343 1152884 complement(3505825..3506994) 1 NC_004342.2 ISlin1 transposase 3506994 1152884 LA_3542 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713722.2 3505825 R 189518 CDS NP_713723.1 24216242 1152885 complement(3507992..3508441) 1 NC_004342.2 hypothetical protein 3508441 1152885 LA_3543 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713723.1 3507992 R 189518 CDS NP_713724.1 24216243 1152886 complement(3508790..3509176) 1 NC_004342.2 hypothetical protein 3509176 1152886 LA_3544 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713724.1 3508790 R 189518 CDS NP_713725.1 24216244 1152887 complement(3509183..3509371) 1 NC_004342.2 hypothetical protein 3509371 1152887 LA_3545 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713725.1 3509183 R 189518 CDS NP_713726.1 24216245 1152888 complement(3509850..3510542) 1 NC_004342.2 SAM-dependent methyltransferase 3510542 1152888 LA_3546 Leptospira interrogans serovar Lai str. 56601 SAM-dependent methyltransferase NP_713726.1 3509850 R 189518 CDS NP_713727.2 294828344 1152889 complement(3510726..3511703) 1 NC_004342.2 hypothetical protein 3511703 1152889 LA_3547 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713727.2 3510726 R 189518 CDS NP_713731.1 24216250 1152893 complement(3512657..3514600) 1 NC_004342.2 5-methylaminomethyl-2-thiouridine methyltransferase 3514600 1152893 LA_3551 Leptospira interrogans serovar Lai str. 56601 5-methylaminomethyl-2-thiouridine methyltransferase NP_713731.1 3512657 R 189518 CDS NP_713732.1 24216251 1152894 complement(3514600..3515616) 1 NC_004342.2 hypothetical protein 3515616 1152894 LA_3552 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713732.1 3514600 R 189518 CDS NP_713734.2 294828345 1152896 3515778..3516821 1 NC_004342.2 tRNA-dihydrouridine synthase A 3516821 1152896 LA_3553 Leptospira interrogans serovar Lai str. 56601 tRNA-dihydrouridine synthase A NP_713734.2 3515778 D 189518 CDS YP_003573347.1 294828346 9006961 3517907..3518350 1 NC_004342.2 hypothetical protein 3518350 9006961 LA_3553a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573347.1 3517907 D 189518 CDS NP_713737.1 24216256 1152899 complement(3518829..3519620) 1 NC_004342.2 ribosomal protein serine acetyltransferase 3519620 1152899 LA_3557 Leptospira interrogans serovar Lai str. 56601 ribosomal protein serine acetyltransferase NP_713737.1 3518829 R 189518 CDS NP_713738.1 24216257 1152900 complement(3520098..3520457) 1 NC_004342.2 metal-sulfur cluster biosynthetic enzyme 3520457 paaD 1152900 paaD Leptospira interrogans serovar Lai str. 56601 metal-sulfur cluster biosynthetic enzyme NP_713738.1 3520098 R 189518 CDS NP_713739.1 24216258 1152901 complement(3520749..3521183) 1 NC_004342.2 NifU-like protein 3521183 iscU 1152901 iscU Leptospira interrogans serovar Lai str. 56601 NifU-like protein NP_713739.1 3520749 R 189518 CDS NP_713740.2 294828347 1152902 complement(3521167..3522408) 1 NC_004342.2 selenocysteine lyase 3522408 csdB 1152902 csdB Leptospira interrogans serovar Lai str. 56601 selenocysteine lyase NP_713740.2 3521167 R 189518 CDS NP_713741.1 24216260 1152903 complement(3522414..3522725) 1 NC_004342.2 benzene 1,2-dioxygenase system ferredoxin component 3522725 nirD 1152903 nirD Leptospira interrogans serovar Lai str. 56601 benzene 1,2-dioxygenase system ferredoxin component NP_713741.1 3522414 R 189518 CDS NP_713742.2 294828348 1152904 complement(3522722..3523945) 1 NC_004342.2 Fe-S cluster assembly ABC transporter permease 3523945 1152904 LA_3562 Leptospira interrogans serovar Lai str. 56601 Fe-S cluster assembly ABC transporter permease NP_713742.2 3522722 R 189518 CDS NP_713743.1 24216262 1152905 complement(3523926..3524693) 1 NC_004342.2 ABC transporter ATP-binding protein 3524693 sufC 1152905 sufC Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_713743.1 3523926 R 189518 CDS NP_713744.1 24216263 1152906 3525398..3525838 1 NC_004342.2 protein required for attachment to host cells 3525838 1152906 LA_3564 Leptospira interrogans serovar Lai str. 56601 protein required for attachment to host cells NP_713744.1 3525398 D 189518 CDS NP_713745.1 24216264 1152907 3526798..3528345 1 NC_004342.2 glycerol kinase 3528345 glpK 1152907 glpK Leptospira interrogans serovar Lai str. 56601 glycerol kinase NP_713745.1 3526798 D 189518 CDS NP_713751.1 24216270 1152913 3529884..3530303 1 NC_004342.2 hypothetical protein 3530303 1152913 LA_3571 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713751.1 3529884 D 189518 CDS YP_003573348.1 294828349 9006962 3530394..3530609 1 NC_004342.2 hypothetical protein 3530609 9006962 LA_3571a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573348.1 3530394 D 189518 CDS NP_713752.1 24216271 1152914 3530658..3530996 1 NC_004342.2 anti-sigma factor antagonist 3530996 1152914 LA_3572 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_713752.1 3530658 D 189518 CDS NP_713753.2 294828350 1152915 complement(3531942..3532685) 1 NC_004342.2 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3532685 kdsB 1152915 kdsB Leptospira interrogans serovar Lai str. 56601 3-deoxy-manno-octulosonate cytidylyltransferase NP_713753.2 3531942 R 189518 CDS NP_713754.1 24216273 1152916 complement(3532685..3533203) 1 NC_004342.2 flagellar basal body protein FliL 3533203 fliL 1152916 fliL Leptospira interrogans serovar Lai str. 56601 flagellar basal body protein FliL NP_713754.1 3532685 R 189518 CDS NP_713755.1 24216274 1152917 complement(3533421..3533945) 1 NC_004342.2 flagellar basal body protein FliL 3533945 fliL 1152917 fliL Leptospira interrogans serovar Lai str. 56601 flagellar basal body protein FliL NP_713755.1 3533421 R 189518 CDS NP_713756.1 24216275 1152918 complement(3533986..3534813) 1 NC_004342.2 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 3534813 motB 1152918 motB Leptospira interrogans serovar Lai str. 56601 flagellar motor protein MotB NP_713756.1 3533986 R 189518 CDS NP_713757.1 24216276 1152919 complement(3534829..3535611) 1 NC_004342.2 endoflagellar motor protein A 3535611 motA 1152919 motA Leptospira interrogans serovar Lai str. 56601 endoflagellar motor protein A NP_713757.1 3534829 R 189518 CDS NP_713758.1 24216277 1152920 complement(3535617..3535841) 1 NC_004342.2 flagellar FlbD family protein 3535841 1152920 LA_3578 Leptospira interrogans serovar Lai str. 56601 flagellar FlbD family protein NP_713758.1 3535617 R 189518 CDS NP_713759.1 24216278 1152921 complement(3535846..3537030) 1 NC_004342.2 glycosyltransferase 3537030 1152921 LA_3579 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_713759.1 3535846 R 189518 CDS NP_713760.1 24216279 1152922 complement(3537112..3537630) 1 NC_004342.2 hypothetical protein 3537630 1152922 LA_3580 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713760.1 3537112 R 189518 CDS NP_713761.1 24216280 1152923 3538021..3538794 1 NC_004342.2 dioxygenase-like protein 3538794 1152923 LA_3581 Leptospira interrogans serovar Lai str. 56601 dioxygenase-like protein NP_713761.1 3538021 D 189518 CDS NP_713762.1 24216281 1152924 complement(3539110..3540621) 1 NC_004342.2 gamma-glutamyl carboxylase-like protein 3540621 1152924 LA_3582 Leptospira interrogans serovar Lai str. 56601 gamma-glutamyl carboxylase-like protein NP_713762.1 3539110 R 189518 CDS NP_713763.1 24216282 1152925 complement(3540578..3541561) 1 NC_004342.2 DNA processing protein A 3541561 smf 1152925 smf Leptospira interrogans serovar Lai str. 56601 DNA processing protein A NP_713763.1 3540578 R 189518 CDS NP_713764.2 294828351 1152926 complement(3541558..3542652) 1 NC_004342.2 hypothetical protein 3542652 1152926 LA_3584 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713764.2 3541558 R 189518 CDS NP_713766.1 24216285 1152928 complement(3544560..3544907) 1 NC_004342.2 hypothetical protein 3544907 1152928 LA_3586 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713766.1 3544560 R 189518 CDS NP_713767.1 24216286 1152929 3545046..3545495 1 NC_004342.2 acetyltransferase 3545495 rimI 1152929 rimI Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_713767.1 3545046 D 189518 CDS NP_713771.1 24216290 1152933 complement(3546930..3547415) 1 NC_004342.2 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3547415 ispF 1152933 ispF Leptospira interrogans serovar Lai str. 56601 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NP_713771.1 3546930 R 189518 CDS NP_713774.1 24216293 1152936 complement(3548044..3548325) 1 NC_004342.2 TPR-repeat-containing protein 3548325 1152936 LA_3594 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_713774.1 3548044 R 189518 CDS NP_713776.1 24216295 1152938 3549503..3552022 1 NC_004342.2 ATP-dependent Lon protease 3552022 lon 1152938 lon Leptospira interrogans serovar Lai str. 56601 ATP-dependent Lon protease NP_713776.1 3549503 D 189518 CDS NP_713777.1 24216296 1152939 3552067..3553191 1 NC_004342.2 pyridoxal phosphate-dependent aminotransferase 3553191 wecE 1152939 wecE Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate-dependent aminotransferase NP_713777.1 3552067 D 189518 CDS NP_713778.2 294828352 1152940 3553676..3554158 1 NC_004342.2 DNA-binding ferritin-like protein 3554158 dps 1152940 dps Leptospira interrogans serovar Lai str. 56601 DNA-binding ferritin-like protein NP_713778.2 3553676 D 189518 CDS NP_713780.1 24216299 1152942 complement(3554672..3555070) 1 NC_004342.2 hypothetical protein 3555070 1152942 LA_3600 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713780.1 3554672 R 189518 CDS NP_713782.1 24216301 1152944 complement(3555830..3556333) 1 NC_004342.2 hypothetical protein 3556333 1152944 LA_3602 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713782.1 3555830 R 189518 CDS NP_713783.2 294828353 1152945 complement(3557374..3559776) 1 NC_004342.2 sulfatase 3559776 1152945 LA_3603 Leptospira interrogans serovar Lai str. 56601 sulfatase NP_713783.2 3557374 R 189518 CDS NP_713785.2 294828354 1152947 3559836..3560780 1 NC_004342.2 lysophospholipase 3560780 pldB 1152947 pldB Leptospira interrogans serovar Lai str. 56601 lysophospholipase NP_713785.2 3559836 D 189518 CDS NP_713786.1 24216305 1152948 3560897..3561349 1 NC_004342.2 hypothetical protein 3561349 1152948 LA_3606 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713786.1 3560897 D 189518 CDS NP_713787.1 24216306 1152949 3561351..3561767 1 NC_004342.2 MaoC-like acyl dehydratase 3561767 maoC 1152949 maoC Leptospira interrogans serovar Lai str. 56601 MaoC-like acyl dehydratase NP_713787.1 3561351 D 189518 CDS NP_713788.2 294828355 1152950 3562238..3562882 1 NC_004342.2 hypothetical protein 3562882 1152950 LA_3608 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713788.2 3562238 D 189518 CDS NP_713789.2 294828356 1152951 complement(3562952..3565051) 1 NC_004342.2 serine phosphatase RsbU 3565051 1152951 LA_3610 Leptospira interrogans serovar Lai str. 56601 serine phosphatase RsbU NP_713789.2 3562952 R 189518 CDS NP_713790.2 294828357 1152952 3565039..3565308 1 NC_004342.2 hypothetical protein 3565308 1152952 LA_3609 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713790.2 3565039 D 189518 CDS NP_713791.1 24216310 1152953 3565952..3566755 1 NC_004342.2 hypothetical protein 3566755 1152953 LA_3611 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713791.1 3565952 D 189518 CDS NP_713792.1 24216311 1152954 3566780..3566977 1 NC_004342.2 hypothetical protein 3566977 1152954 LA_3612 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713792.1 3566780 D 189518 CDS NP_713793.1 24216312 1152955 complement(3567866..3568912) 1 NC_004342.2 catalyzes the formation of 2-dehydropantoate from (R)-pantoate; 2-dehydropantoate 2-reductase 3568912 apbA 1152955 apbA Leptospira interrogans serovar Lai str. 56601 2-dehydropantoate 2-reductase NP_713793.1 3567866 R 189518 CDS NP_713794.2 294828358 1152956 complement(3569017..3571614) 1 NC_004342.2 signal transduction protein 3571614 1152956 LA_3614 Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_713794.2 3569017 R 189518 CDS NP_713795.1 24216314 1152957 complement(3571831..3573258) 1 NC_004342.2 OmpA family protein 3573258 1152957 LA_3615 Leptospira interrogans serovar Lai str. 56601 OmpA family protein NP_713795.1 3571831 R 189518 CDS NP_713796.1 24216315 1152958 3573325..3573645 1 NC_004342.2 divalent ion tolerance protein 3573645 cutA 1152958 cutA Leptospira interrogans serovar Lai str. 56601 divalent ion tolerance protein NP_713796.1 3573325 D 189518 CDS NP_713797.2 294828359 1152959 3573670..3574182 1 NC_004342.2 esterase 3574182 1152959 LA_3617 Leptospira interrogans serovar Lai str. 56601 esterase NP_713797.2 3573670 D 189518 CDS NP_713798.1 24216317 1152960 complement(3574159..3574464) 1 NC_004342.2 ISlin1 transposase 3574464 1152960 LA_3618 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713798.1 3574159 R 189518 CDS NP_713799.2 294828360 1152961 complement(3574448..3575329) 1 NC_004342.2 ISlin1 transposase 3575329 1152961 LA_3619 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_713799.2 3574448 R 189518 CDS NP_713800.1 24216319 1152962 3575484..3575864 1 NC_004342.2 hypothetical protein 3575864 1152962 LA_3620 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713800.1 3575484 D 189518 CDS NP_713802.1 24216321 1152964 complement(3577147..3579492) 1 NC_004342.2 ammonium transporter 3579492 amtB 1152964 amtB Leptospira interrogans serovar Lai str. 56601 ammonium transporter NP_713802.1 3577147 R 189518 CDS NP_713803.1 24216322 1152965 complement(3580346..3581122) 1 NC_004342.2 glutamine amidotransferase 3581122 1152965 LA_3623 Leptospira interrogans serovar Lai str. 56601 glutamine amidotransferase NP_713803.1 3580346 R 189518 CDS NP_713804.1 24216323 1152966 3582027..3583133 1 NC_004342.2 glycosyltransferase 3583133 1152966 LA_3624 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_713804.1 3582027 D 189518 CDS NP_713805.1 24216324 1152967 3583130..3585883 1 NC_004342.2 DNA polymerase I 3585883 polA 1152967 polA Leptospira interrogans serovar Lai str. 56601 DNA polymerase I NP_713805.1 3583130 D 189518 CDS YP_003573349.1 294828361 9006963 complement(3586662..3586910) 1 NC_004342.2 hypothetical protein 3586910 9006963 LA_3625a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573349.1 3586662 R 189518 CDS NP_713807.1 24216326 1152969 3586928..3588241 1 NC_004342.2 acyl-CoA dehydrogenase 3588241 caiA 1152969 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_713807.1 3586928 D 189518 CDS NP_713808.1 24216327 1152970 3588328..3589749 1 NC_004342.2 anthranilate synthase component I 3589749 trpE 1152970 trpE Leptospira interrogans serovar Lai str. 56601 anthranilate synthase component I NP_713808.1 3588328 D 189518 CDS NP_713809.2 294828362 1152971 3589749..3590327 1 NC_004342.2 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 3590327 pabA 1152971 pabA Leptospira interrogans serovar Lai str. 56601 anthranilate synthase component II NP_713809.2 3589749 D 189518 CDS NP_713810.2 294828363 1152972 3590399..3592219 1 NC_004342.2 multidrug ABC transporter ATPase/permease 3592219 mdlB 1152972 mdlB Leptospira interrogans serovar Lai str. 56601 multidrug ABC transporter ATPase/permease NP_713810.2 3590399 D 189518 CDS NP_713811.1 24216330 1152973 3592216..3592629 1 NC_004342.2 receiver component of a two-component response regulator 3592629 1152973 LA_3631 Leptospira interrogans serovar Lai str. 56601 receiver component of a two-component response regulator NP_713811.1 3592216 D 189518 CDS NP_713812.1 24216331 1152974 complement(3592618..3594078) 1 NC_004342.2 FOG:HEAT repeat protein 3594078 1152974 LA_3632 Leptospira interrogans serovar Lai str. 56601 FOG:HEAT repeat protein NP_713812.1 3592618 R 189518 CDS NP_713814.1 24216333 1152976 3594439..3595995 1 NC_004342.2 GTP-binding protein 3595995 hflX 1152976 hflX Leptospira interrogans serovar Lai str. 56601 GTP-binding protein NP_713814.1 3594439 D 189518 CDS NP_713816.1 24216335 1152978 complement(3596775..3598049) 1 NC_004342.2 cyclic amidohydrolase 3598049 pyrC 1152978 pyrC Leptospira interrogans serovar Lai str. 56601 cyclic amidohydrolase NP_713816.1 3596775 R 189518 CDS YP_003573350.1 294828364 9006964 complement(3598046..3598177) 1 NC_004342.2 IS1533 transposase 3598177 9006964 LA_3636a Leptospira interrogans serovar Lai str. 56601 IS1533 transposase YP_003573350.1 3598046 R 189518 CDS NP_713817.1 24216336 1152979 complement(3599613..3600224) 1 NC_004342.2 hypothetical protein 3600224 1152979 LA_3637 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713817.1 3599613 R 189518 CDS NP_713818.1 24216337 1152980 3600366..3601655 1 NC_004342.2 homoserine dehydrogenase 3601655 thrA 1152980 thrA Leptospira interrogans serovar Lai str. 56601 homoserine dehydrogenase NP_713818.1 3600366 D 189518 CDS NP_713819.1 24216338 1152981 3601753..3602127 1 NC_004342.2 anti-Sigma factor antagonist 3602127 1152981 LA_3639 Leptospira interrogans serovar Lai str. 56601 anti-Sigma factor antagonist NP_713819.1 3601753 D 189518 CDS NP_713820.1 24216339 1152982 3602995..3603534 1 NC_004342.2 hypothetical protein 3603534 1152982 LA_3640 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713820.1 3602995 D 189518 CDS NP_713821.1 24216340 1152983 complement(3603600..3604343) 1 NC_004342.2 acetyltransferase 3604343 1152983 LA_3641 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_713821.1 3603600 R 189518 CDS NP_713822.1 24216341 1152984 complement(3604566..3604754) 1 NC_004342.2 hypothetical protein 3604754 1152984 LA_3642 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713822.1 3604566 R 189518 CDS NP_713824.1 24216343 1152986 complement(3605316..3606119) 1 NC_004342.2 enoyl-CoA hydratase 3606119 1152986 LA_3644 Leptospira interrogans serovar Lai str. 56601 enoyl-CoA hydratase NP_713824.1 3605316 R 189518 CDS NP_713825.1 24216344 1152987 complement(3606427..3606780) 1 NC_004342.2 single-stranded DNA-binding protein 3606780 ssb 1152987 ssb Leptospira interrogans serovar Lai str. 56601 single-stranded DNA-binding protein NP_713825.1 3606427 R 189518 CDS NP_713826.2 294828365 1152988 complement(3607447..3608184) 1 NC_004342.2 SCO2/SenC family protein 3608184 1152988 LA_3646 Leptospira interrogans serovar Lai str. 56601 SCO2/SenC family protein NP_713826.2 3607447 R 189518 CDS NP_713828.1 24216347 1152990 complement(3609225..3609782) 1 NC_004342.2 hypothetical protein 3609782 1152990 LA_3648 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713828.1 3609225 R 189518 CDS NP_713829.2 294828366 1152991 complement(3609769..3610659) 1 NC_004342.2 hypothetical protein 3610659 1152991 LA_3649 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713829.2 3609769 R 189518 CDS NP_713831.1 24216350 1152993 complement(3612075..3612338) 1 NC_004342.2 hypothetical protein 3612338 1152993 LA_3651 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713831.1 3612075 R 189518 CDS NP_713832.1 24216351 1152994 complement(3612328..3612873) 1 NC_004342.2 RNA polymerase ECF-type sigma factor 3612873 rpoE 1152994 rpoE Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_713832.1 3612328 R 189518 CDS NP_713833.2 294828367 1152995 complement(3612863..3613342) 1 NC_004342.2 hypothetical protein 3613342 1152995 LA_3653 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713833.2 3612863 R 189518 CDS NP_713837.1 24216356 1152999 complement(3614732..3615415) 1 NC_004342.2 two-component response regulator 3615415 1152999 LA_3657 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_713837.1 3614732 R 189518 CDS NP_713839.1 24216358 1153001 complement(3616910..3617650) 1 NC_004342.2 hypothetical protein 3617650 1153001 LA_3659 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713839.1 3616910 R 189518 CDS NP_713840.2 294828368 1153002 3617982..3618452 1 NC_004342.2 ketosteroid isomerase-like protein 3618452 1153002 LA_3660 Leptospira interrogans serovar Lai str. 56601 ketosteroid isomerase-like protein NP_713840.2 3617982 D 189518 CDS NP_713841.1 24216360 1153003 3618677..3619477 1 NC_004342.2 hydrolase 3619477 1153003 LA_3661 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_713841.1 3618677 D 189518 CDS NP_713842.1 24216361 1153004 3619478..3621568 1 NC_004342.2 two-component hybrid sensor and regulator 3621568 1153004 LA_3662 Leptospira interrogans serovar Lai str. 56601 two-component hybrid sensor and regulator NP_713842.1 3619478 D 189518 CDS NP_713843.2 294828369 1153005 complement(3622003..3623109) 1 NC_004342.2 hypothetical protein 3623109 1153005 LA_3664 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713843.2 3622003 R 189518 CDS NP_713845.2 294828370 1153007 3623886..3624224 1 NC_004342.2 anti-sigma factor antagonist 3624224 1153007 LA_3665 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_713845.2 3623886 D 189518 CDS NP_713846.1 24216365 1153008 3624221..3624814 1 NC_004342.2 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3624814 1153008 LA_3666 Leptospira interrogans serovar Lai str. 56601 deoxyribonucleotide triphosphate pyrophosphatase NP_713846.1 3624221 D 189518 CDS NP_713848.2 294828371 1153010 3626104..3626760 1 NC_004342.2 uracil-DNA glycosylase 3626760 1153010 LA_3668 Leptospira interrogans serovar Lai str. 56601 uracil-DNA glycosylase NP_713848.2 3626104 D 189518 CDS NP_713849.2 294828372 1153011 complement(3626726..3627769) 1 NC_004342.2 hypothetical protein 3627769 1153011 LA_3669 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713849.2 3626726 R 189518 CDS NP_713852.1 24216371 1153014 complement(3628157..3629230) 1 NC_004342.2 hydrolase/acyltransferase 3629230 1153014 LA_3672 Leptospira interrogans serovar Lai str. 56601 hydrolase/acyltransferase NP_713852.1 3628157 R 189518 CDS NP_713853.2 294828373 1153015 complement(3629457..3629984) 1 NC_004342.2 peptide methionine sulfoxide reductase 3629984 msrA 1153015 msrA Leptospira interrogans serovar Lai str. 56601 peptide methionine sulfoxide reductase NP_713853.2 3629457 R 189518 CDS NP_713855.2 294828374 1153017 complement(3630434..3631903) 1 NC_004342.2 hypothetical protein 3631903 1153017 LA_3675 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713855.2 3630434 R 189518 CDS NP_713856.1 24216375 1153018 3632406..3634121 1 NC_004342.2 acyl-CoA dehydrogenase 3634121 caiA 1153018 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_713856.1 3632406 D 189518 CDS NP_713857.1 24216376 1153019 3634123..3634248 1 NC_004342.2 hypothetical protein 3634248 1153019 LA_3677 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713857.1 3634123 D 189518 CDS NP_713859.1 24216378 1153021 3635726..3636382 1 NC_004342.2 acetyltransferase 3636382 wbbJ 1153021 wbbJ Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_713859.1 3635726 D 189518 CDS NP_713860.1 24216379 1153022 3637385..3637705 1 NC_004342.2 hypothetical protein 3637705 1153022 LA_3680 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713860.1 3637385 D 189518 CDS NP_713861.1 24216380 1153023 complement(3637687..3639024) 1 NC_004342.2 hypothetical protein 3639024 1153023 LA_3681 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713861.1 3637687 R 189518 CDS NP_713864.1 24216383 1153026 complement(3640325..3641959) 1 NC_004342.2 ABC transporter ATPase 3641959 uup 1153026 uup Leptospira interrogans serovar Lai str. 56601 ABC transporter ATPase NP_713864.1 3640325 R 189518 CDS NP_713865.1 24216384 1153027 3642060..3644042 1 NC_004342.2 OmpA family protein 3644042 1153027 LA_3685 Leptospira interrogans serovar Lai str. 56601 OmpA family protein NP_713865.1 3642060 D 189518 CDS NP_713868.1 24216387 1153030 3645606..3646406 1 NC_004342.2 hypothetical protein 3646406 1153030 LA_3688 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713868.1 3645606 D 189518 CDS NP_713870.1 24216389 1153032 3646780..3647583 1 NC_004342.2 hypothetical protein 3647583 1153032 LA_3690 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713870.1 3646780 D 189518 CDS NP_713872.1 24216391 1153034 3647921..3650347 1 NC_004342.2 membrane carboxypeptidase/penicillin-binding protein 3650347 mrcA 1153034 mrcA Leptospira interrogans serovar Lai str. 56601 membrane carboxypeptidase/penicillin-binding protein NP_713872.1 3647921 D 189518 CDS NP_713873.1 24216392 1153035 complement(3650325..3651884) 1 NC_004342.2 dipeptide ABC transporter periplasmic 3651884 1153035 LA_3693 Leptospira interrogans serovar Lai str. 56601 dipeptide ABC transporter periplasmic NP_713873.1 3650325 R 189518 CDS NP_713874.2 294828375 1153036 3651935..3653764 1 NC_004342.2 multidrug ABC transporter ATPase/permease 3653764 mdlB 1153036 mdlB Leptospira interrogans serovar Lai str. 56601 multidrug ABC transporter ATPase/permease NP_713874.2 3651935 D 189518 CDS NP_713875.1 24216394 1153037 3653788..3654831 1 NC_004342.2 tetraacyldisaccharide 4'-kinase 3654831 lpxK 1153037 lpxK Leptospira interrogans serovar Lai str. 56601 tetraacyldisaccharide 4'-kinase NP_713875.1 3653788 D 189518 CDS NP_713876.1 24216395 1153038 3655743..3656222 1 NC_004342.2 hypothetical protein 3656222 1153038 LA_3696 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713876.1 3655743 D 189518 CDS NP_713877.2 294828376 1153039 complement(3656686..3658710) 1 NC_004342.2 hypothetical protein 3658710 1153039 LA_3697 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713877.2 3656686 R 189518 CDS YP_003573351.1 294828377 9006965 3658694..3658825 1 NC_004342.2 hypothetical protein 3658825 9006965 LA_3697a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573351.1 3658694 D 189518 CDS NP_713878.1 24216397 1153040 complement(3658849..3660657) 1 NC_004342.2 transpeptidase/penicillin binding protein 3660657 ftsI 1153040 ftsI Leptospira interrogans serovar Lai str. 56601 transpeptidase/penicillin binding protein NP_713878.1 3658849 R 189518 CDS NP_713879.1 24216398 1153041 3661050..3661676 1 NC_004342.2 arsenate reductase 3661676 1153041 LA_3699 Leptospira interrogans serovar Lai str. 56601 arsenate reductase NP_713879.1 3661050 D 189518 CDS NP_713883.1 24216402 1153045 3662933..3663961 1 NC_004342.2 heat shock operon regulator HrcA 3663961 hrcA 1153045 hrcA Leptospira interrogans serovar Lai str. 56601 heat shock operon regulator HrcA NP_713883.1 3662933 D 189518 CDS NP_713884.1 24216403 1153046 3663975..3664613 1 NC_004342.2 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 3664613 grpE 1153046 grpE Leptospira interrogans serovar Lai str. 56601 heat shock protein GrpE NP_713884.1 3663975 D 189518 CDS NP_713885.1 24216404 1153047 3664648..3666588 1 NC_004342.2 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 3666588 dnaK 1153047 dnaK Leptospira interrogans serovar Lai str. 56601 molecular chaperone DnaK NP_713885.1 3664648 D 189518 CDS NP_713887.1 24216406 1153049 3666881..3667999 1 NC_004342.2 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 3667999 dnaJ 1153049 dnaJ Leptospira interrogans serovar Lai str. 56601 molecular chaperone DnaJ NP_713887.1 3666881 D 189518 CDS NP_713889.1 24216408 1153051 3668285..3669253 1 NC_004342.2 oxidoreductase 3669253 mviM 1153051 mviM Leptospira interrogans serovar Lai str. 56601 oxidoreductase NP_713889.1 3668285 D 189518 CDS NP_713890.1 24216409 1153052 3669277..3669825 1 NC_004342.2 transcriptional regulator 3669825 1153052 LA_3710 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_713890.1 3669277 D 189518 CDS NP_713891.1 24216410 1153053 3670387..3670671 1 NC_004342.2 hypothetical protein 3670671 1153053 LA_3711 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713891.1 3670387 D 189518 CDS NP_713892.1 24216411 1153054 complement(3670990..3673527) 1 NC_004342.2 lysophospholipase L1 biosynthesis ABC transporter permease 3673527 1153054 LA_3712 Leptospira interrogans serovar Lai str. 56601 lysophospholipase L1 biosynthesis ABC transporter permease NP_713892.1 3670990 R 189518 CDS NP_713893.2 294828378 1153055 complement(3673524..3674306) 1 NC_004342.2 antimicrobial peptide ABC transporter ATPase 3674306 salX 1153055 salX Leptospira interrogans serovar Lai str. 56601 antimicrobial peptide ABC transporter ATPase NP_713893.2 3673524 R 189518 CDS NP_713894.2 161484947 1153056 3674785..3677376 1 NC_004342.2 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 3677376 leuS 1153056 leuS Leptospira interrogans serovar Lai str. 56601 leucyl-tRNA synthetase NP_713894.2 3674785 D 189518 CDS NP_713896.2 294828379 1153058 complement(3679288..3679581) 1 NC_004342.2 hypothetical protein 3679581 1153058 LA_3716 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713896.2 3679288 R 189518 CDS NP_713898.1 24216417 1153060 3680306..3681256 1 NC_004342.2 transposase 3681256 1153060 LA_3718 Leptospira interrogans serovar Lai str. 56601 transposase NP_713898.1 3680306 D 189518 CDS NP_713899.1 24216418 1153061 complement(3681285..3681944) 1 NC_004342.2 hypothetical protein 3681944 1153061 LA_3719 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713899.1 3681285 R 189518 CDS NP_713900.1 24216419 1153062 complement(3682077..3683054) 1 NC_004342.2 nuclease-like protein 3683054 1153062 LA_3720 Leptospira interrogans serovar Lai str. 56601 nuclease-like protein NP_713900.1 3682077 R 189518 CDS NP_713902.1 24216421 1153064 complement(3683600..3684532) 1 NC_004342.2 hypothetical protein 3684532 1153064 LA_3722 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713902.1 3683600 R 189518 CDS NP_713903.2 294828380 1153065 complement(3684599..3684790) 1 NC_004342.2 hypothetical protein 3684790 1153065 LA_3723 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713903.2 3684599 R 189518 CDS NP_713904.2 294828381 1153066 complement(3685108..3685716) 1 NC_004342.2 hypothetical protein 3685716 1153066 LA_3724 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713904.2 3685108 R 189518 CDS NP_713905.1 24216424 1153067 complement(3685731..3694088) 1 NC_004342.2 cytoplasmic membrane protein 3694088 1153067 LA_3725 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713905.1 3685731 R 189518 CDS NP_713906.1 24216425 1153068 complement(3694229..3695761) 1 NC_004342.2 hypothetical protein 3695761 1153068 LA_3726 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713906.1 3694229 R 189518 CDS NP_713907.2 294828382 1153069 complement(3695979..3696404) 1 NC_004342.2 hypothetical protein 3696404 1153069 LA_3727 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713907.2 3695979 R 189518 CDS NP_713909.1 24216428 1153071 complement(3697024..3697563) 1 NC_004342.2 Fimh-like protein 3697563 1153071 LA_3729 Leptospira interrogans serovar Lai str. 56601 Fimh-like protein NP_713909.1 3697024 R 189518 CDS NP_713910.1 24216429 1153072 complement(3698105..3700972) 1 NC_004342.2 hypothetical protein 3700972 1153072 LA_3730 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713910.1 3698105 R 189518 CDS NP_713911.2 294828383 1153073 complement(3701541..3704720) 1 NC_004342.2 hypothetical protein 3704720 1153073 LA_3731 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713911.2 3701541 R 189518 CDS NP_713913.2 294828384 1153075 3705184..3706713 1 NC_004342.2 TolC-like outer membrane protein 3706713 1153075 LA_3733 Leptospira interrogans serovar Lai str. 56601 TolC-like outer membrane protein NP_713913.2 3705184 D 189518 CDS NP_713914.1 24216433 1153076 3706725..3708551 1 NC_004342.2 cytoplasmic membrane protein 3708551 1153076 LA_3734 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_713914.1 3706725 D 189518 CDS NP_713915.1 24216434 1153077 3708575..3709270 1 NC_004342.2 hypothetical protein 3709270 1153077 LA_3735 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713915.1 3708575 D 189518 CDS NP_713916.2 294828385 1153078 3709281..3709913 1 NC_004342.2 TPR-repeat-containing protein 3709913 1153078 LA_3736 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_713916.2 3709281 D 189518 CDS NP_713917.1 24216436 1153079 3710260..3711753 1 NC_004342.2 heavy metal efflux pump 3711753 acrA 1153079 acrA Leptospira interrogans serovar Lai str. 56601 heavy metal efflux pump NP_713917.1 3710260 D 189518 CDS NP_713918.1 24216437 1153080 3711750..3714830 1 NC_004342.2 acriflavine resistance protein 3714830 1153080 LA_3738 Leptospira interrogans serovar Lai str. 56601 acriflavine resistance protein NP_713918.1 3711750 D 189518 CDS NP_713919.2 294828386 1153081 3714926..3715792 1 NC_004342.2 acriflavine resistance protein 3715792 1153081 LA_3739 Leptospira interrogans serovar Lai str. 56601 acriflavine resistance protein NP_713919.2 3714926 D 189518 CDS NP_713920.1 24216439 1153082 3715779..3717728 1 NC_004342.2 acriflavine resistance protein 3717728 1153082 LA_3740 Leptospira interrogans serovar Lai str. 56601 acriflavine resistance protein NP_713920.1 3715779 D 189518 CDS NP_713921.2 294828387 1153083 3717715..3718428 1 NC_004342.2 hypothetical protein 3718428 1153083 LA_3741 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713921.2 3717715 D 189518 CDS NP_713922.1 24216441 1153084 3718425..3719120 1 NC_004342.2 hypothetical protein 3719120 1153084 LA_3742 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713922.1 3718425 D 189518 CDS NP_713924.1 24216443 1153086 complement(3720036..3721109) 1 NC_004342.2 hypothetical protein 3721109 1153086 LA_3744 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713924.1 3720036 R 189518 CDS NP_713925.1 24216444 1153087 complement(3721121..3721846) 1 NC_004342.2 hypothetical protein 3721846 1153087 LA_3745 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713925.1 3721121 R 189518 CDS NP_713927.1 24216446 1153089 complement(3722355..3723704) 1 NC_004342.2 threonine synthase 3723704 thrC 1153089 thrC Leptospira interrogans serovar Lai str. 56601 threonine synthase NP_713927.1 3722355 R 189518 CDS NP_713928.1 24216447 1153090 complement(3723708..3724700) 1 NC_004342.2 hypothetical protein 3724700 1153090 LA_3748 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713928.1 3723708 R 189518 CDS NP_713929.1 24216448 1153091 complement(3724791..3725372) 1 NC_004342.2 hypothetical protein 3725372 1153091 LA_3749 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713929.1 3724791 R 189518 CDS NP_713931.1 24216450 1153093 3725624..3727219 1 NC_004342.2 hypothetical protein 3727219 1153093 LA_3751 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713931.1 3725624 D 189518 CDS NP_713932.1 24216451 1153094 3727560..3729095 1 NC_004342.2 hypothetical protein 3729095 1153094 LA_3752 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713932.1 3727560 D 189518 CDS NP_713933.2 294828388 1153095 3730039..3731622 1 NC_004342.2 hypothetical protein 3731622 1153095 LA_3753 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713933.2 3730039 D 189518 CDS NP_713934.1 24216453 1153096 3731666..3732262 1 NC_004342.2 signal peptidase I 3732262 1153096 LA_3754 Leptospira interrogans serovar Lai str. 56601 signal peptidase I NP_713934.1 3731666 D 189518 CDS NP_713936.2 294828389 1153098 complement(3732847..3733413) 1 NC_004342.2 acetyltransferase 3733413 rimL 1153098 rimL Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_713936.2 3732847 R 189518 CDS NP_713938.1 24216457 1153100 3733777..3734037 1 NC_004342.2 RNA-binding protein 3734037 1153100 LA_3758 Leptospira interrogans serovar Lai str. 56601 RNA-binding protein NP_713938.1 3733777 D 189518 CDS NP_713942.1 24216461 1153104 3735205..3735633 1 NC_004342.2 hypothetical protein 3735633 1153104 LA_3762 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713942.1 3735205 D 189518 CDS NP_713943.2 161484946 1153105 3735812..3738460 1 NC_004342.2 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 3738460 valS 1153105 valS Leptospira interrogans serovar Lai str. 56601 valyl-tRNA synthetase NP_713943.2 3735812 D 189518 CDS NP_713944.2 294828390 1153106 3738462..3739730 1 NC_004342.2 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 3739730 purD 1153106 purD Leptospira interrogans serovar Lai str. 56601 phosphoribosylamine--glycine ligase NP_713944.2 3738462 D 189518 CDS NP_713945.1 24216464 1153107 3739732..3740577 1 NC_004342.2 hypothetical protein 3740577 1153107 LA_3765 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713945.1 3739732 D 189518 CDS NP_713947.1 24216466 1153109 3741459..3742562 1 NC_004342.2 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 3742562 prfB 1153109 prfB Leptospira interrogans serovar Lai str. 56601 peptide chain release factor 2 NP_713947.1 3741459 D 189518 CDS NP_713949.1 24216468 1153111 3742737..3743390 1 NC_004342.2 hypothetical protein 3743390 1153111 LA_3769 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713949.1 3742737 D 189518 CDS NP_713950.1 24216469 1153112 3743453..3744226 1 NC_004342.2 alpha/beta hydrolase 3744226 1153112 LA_3770 Leptospira interrogans serovar Lai str. 56601 alpha/beta hydrolase NP_713950.1 3743453 D 189518 CDS NP_713954.1 24216473 1153116 3745383..3745682 1 NC_004342.2 transposase 3745682 1153116 LA_3774 Leptospira interrogans serovar Lai str. 56601 transposase NP_713954.1 3745383 D 189518 CDS NP_713955.2 294828391 1153117 3745688..3746530 1 NC_004342.2 transposase 3746530 tra5 1153117 tra5 Leptospira interrogans serovar Lai str. 56601 transposase NP_713955.2 3745688 D 189518 CDS NP_713957.2 294828392 1153119 3747679..3747996 1 NC_004342.2 CrcB-like protein 3747996 crcB 1153119 crcB Leptospira interrogans serovar Lai str. 56601 CrcB-like protein NP_713957.2 3747679 D 189518 CDS NP_713958.2 294828393 1153120 3748446..3754115 1 NC_004342.2 LigB-like protein 3754115 1153120 LA_3778 Leptospira interrogans serovar Lai str. 56601 LigB-like protein NP_713958.2 3748446 D 189518 CDS NP_713959.2 294828394 1153121 3754159..3754596 1 NC_004342.2 hypothetical protein 3754596 1153121 LA_3779 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713959.2 3754159 D 189518 CDS NP_713960.2 294828395 1153122 3754613..3754951 1 NC_004342.2 hypothetical protein 3754951 1153122 LA_3780 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713960.2 3754613 D 189518 CDS NP_713961.1 24216480 1153123 3754961..3755299 1 NC_004342.2 hypothetical protein 3755299 1153123 LA_3781 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713961.1 3754961 D 189518 CDS NP_713962.1 24216481 1153124 complement(3755281..3755685) 1 NC_004342.2 glyoxalase/bleomycin resistance protein/dioxygenase 3755685 1153124 LA_3782 Leptospira interrogans serovar Lai str. 56601 glyoxalase/bleomycin resistance protein/dioxygenase NP_713962.1 3755281 R 189518 CDS NP_713963.1 24216482 1153125 complement(3755939..3757267) 1 NC_004342.2 adenosine deaminase 3757267 add 1153125 add Leptospira interrogans serovar Lai str. 56601 adenosine deaminase NP_713963.1 3755939 R 189518 CDS NP_713968.1 24216487 1153130 3758706..3759557 1 NC_004342.2 hydrolase 3759557 1153130 LA_3788 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_713968.1 3758706 D 189518 CDS NP_713969.1 24216488 1153131 3759918..3760712 1 NC_004342.2 hypothetical protein 3760712 1153131 LA_3789 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713969.1 3759918 D 189518 CDS NP_713970.2 294828396 1153132 3760793..3761239 1 NC_004342.2 hypothetical protein 3761239 1153132 LA_3790 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713970.2 3760793 D 189518 CDS NP_713973.1 24216492 1153135 3762196..3762975 1 NC_004342.2 hemolysin 3762975 1153135 LA_3793 Leptospira interrogans serovar Lai str. 56601 hemolysin NP_713973.1 3762196 D 189518 CDS NP_713974.1 24216493 1153136 3763058..3764149 1 NC_004342.2 hypothetical protein 3764149 1153136 LA_3794 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713974.1 3763058 D 189518 CDS NP_713975.1 24216494 1153137 complement(3765149..3765844) 1 NC_004342.2 glycosyltransferase 3765844 1153137 LA_3795 Leptospira interrogans serovar Lai str. 56601 glycosyltransferase NP_713975.1 3765149 R 189518 CDS NP_713976.1 24216495 1153138 complement(3765847..3766638) 1 NC_004342.2 hypothetical protein 3766638 1153138 LA_3796 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713976.1 3765847 R 189518 CDS NP_713977.2 294828397 1153139 complement(3766651..3767721) 1 NC_004342.2 hypothetical protein 3767721 1153139 LA_3797 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713977.2 3766651 R 189518 CDS NP_713978.2 294828398 1153140 complement(3767721..3768128) 1 NC_004342.2 hypothetical protein 3768128 1153140 LA_3798 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713978.2 3767721 R 189518 CDS NP_713979.1 24216498 1153141 3768881..3769147 1 NC_004342.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 3769147 rpsT 1153141 rpsT Leptospira interrogans serovar Lai str. 56601 30S ribosomal protein S20 NP_713979.1 3768881 D 189518 CDS NP_713980.1 24216499 1153142 3769267..3770649 1 NC_004342.2 phosphomannomutase 3770649 manB 1153142 manB Leptospira interrogans serovar Lai str. 56601 phosphomannomutase NP_713980.1 3769267 D 189518 CDS NP_713981.1 24216500 1153143 3770652..3772484 1 NC_004342.2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 3772484 glmS 1153143 glmS Leptospira interrogans serovar Lai str. 56601 glucosamine--fructose-6-phosphate aminotransferase NP_713981.1 3770652 D 189518 CDS NP_713982.1 24216501 1153144 3772490..3773536 1 NC_004342.2 glucose-1-phosphate thymidylyltransferase 3773536 1153144 LA_3802 Leptospira interrogans serovar Lai str. 56601 glucose-1-phosphate thymidylyltransferase NP_713982.1 3772490 D 189518 CDS NP_713983.1 24216502 1153145 3773553..3775163 1 NC_004342.2 acetyl-CoA carboxylase carboxyltransferase component 3775163 1153145 LA_3803 Leptospira interrogans serovar Lai str. 56601 acetyl-CoA carboxylase carboxyltransferase component NP_713983.1 3773553 D 189518 CDS NP_713985.1 24216504 1153147 3776302..3776508 1 NC_004342.2 hypothetical protein 3776508 1153147 LA_3805 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713985.1 3776302 D 189518 CDS NP_713986.2 294828399 1153148 3776603..3777850 1 NC_004342.2 ammonium transporter 3777850 amtB 1153148 amtB Leptospira interrogans serovar Lai str. 56601 ammonium transporter NP_713986.2 3776603 D 189518 CDS NP_713987.1 24216506 1153149 3777889..3778233 1 NC_004342.2 nitrogen regulatory protein P-II 3778233 glnK 1153149 glnK Leptospira interrogans serovar Lai str. 56601 nitrogen regulatory protein P-II NP_713987.1 3777889 D 189518 CDS NP_713989.1 24216508 1153151 3778766..3780799 1 NC_004342.2 hypothetical protein 3780799 1153151 LA_3809 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713989.1 3778766 D 189518 CDS NP_713991.2 294828400 1153153 3781693..3783054 1 NC_004342.2 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 3783054 1153153 LA_3811 Leptospira interrogans serovar Lai str. 56601 spermidine synthase NP_713991.2 3781693 D 189518 CDS NP_713992.1 24216511 1153154 complement(3783091..3783309) 1 NC_004342.2 hypothetical protein 3783309 1153154 LA_3812 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713992.1 3783091 R 189518 CDS NP_713994.2 294828401 1153156 complement(3783800..3784279) 1 NC_004342.2 hypothetical protein 3784279 1153156 LA_3814 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713994.2 3783800 R 189518 CDS NP_713996.1 24216515 1153158 3784853..3785242 1 NC_004342.2 hypothetical protein 3785242 1153158 LA_3816 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713996.1 3784853 D 189518 CDS NP_713998.1 24216517 1153160 complement(3786026..3786496) 1 NC_004342.2 hypothetical protein 3786496 1153160 LA_3818 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_713998.1 3786026 R 189518 CDS NP_713999.1 24216518 1153161 complement(3786493..3788460) 1 NC_004342.2 ATP-dependent Zn protease 3788460 hflB 1153161 hflB Leptospira interrogans serovar Lai str. 56601 ATP-dependent Zn protease NP_713999.1 3786493 R 189518 CDS NP_714000.1 24216519 1153162 complement(3788620..3789183) 1 NC_004342.2 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 3789183 pth 1153162 pth Leptospira interrogans serovar Lai str. 56601 peptidyl-tRNA hydrolase NP_714000.1 3788620 R 189518 CDS NP_714001.1 24216520 1153163 complement(3789230..3789868) 1 NC_004342.2 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 3789868 rplY 1153163 rplY Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L25 NP_714001.1 3789230 R 189518 CDS NP_714002.1 24216521 1153164 complement(3789886..3790824) 1 NC_004342.2 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 3790824 prsA 1153164 prsA Leptospira interrogans serovar Lai str. 56601 ribose-phosphate pyrophosphokinase NP_714002.1 3789886 R 189518 CDS NP_714003.1 24216522 1153165 complement(3790821..3791579) 1 NC_004342.2 UDP-N-acetylglucosamine diphosphorylase 3791579 glmU 1153165 glmU Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylglucosamine diphosphorylase NP_714003.1 3790821 R 189518 CDS NP_714004.1 24216523 1153166 complement(3791685..3792578) 1 NC_004342.2 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 3792578 ispE 1153166 ispE Leptospira interrogans serovar Lai str. 56601 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_714004.1 3791685 R 189518 CDS NP_714005.2 294828402 1153167 complement(3793081..3793992) 1 NC_004342.2 transcriptional regulator 3793992 1153167 LA_3825 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_714005.2 3793081 R 189518 CDS YP_003573352.1 294828403 9006968 3795369..3796814 1 NC_004342.2 hypothetical protein 3796814 9006968 LA_2825a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573352.1 3795369 D 189518 CDS NP_714007.1 24216526 1153169 3796884..3797438 1 NC_004342.2 hypothetical protein 3797438 1153169 LA_3827 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714007.1 3796884 D 189518 CDS NP_714008.2 294828404 1153170 3797995..3798192 1 NC_004342.2 hypothetical protein 3798192 1153170 LA_3828 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714008.2 3797995 D 189518 CDS NP_714009.1 24216528 1153171 complement(3798546..3798881) 1 NC_004342.2 hypothetical protein 3798881 1153171 LA_3829 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714009.1 3798546 R 189518 CDS NP_714010.2 294828405 1153172 3800522..3801691 1 NC_004342.2 ISlin1 transposase 3801691 1153172 LA_3830 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714010.2 3800522 D 189518 CDS NP_714012.2 294828406 1153174 complement(3802179..3802760) 1 NC_004342.2 3-methyl-adenine DNA glycosylase I 3802760 tag 1153174 tag Leptospira interrogans serovar Lai str. 56601 3-methyl-adenine DNA glycosylase I NP_714012.2 3802179 R 189518 CDS NP_714013.1 24216532 1153175 complement(3803346..3804359) 1 NC_004342.2 hypothetical protein 3804359 1153175 LA_3833 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714013.1 3803346 R 189518 CDS NP_714014.1 24216533 1153176 3804754..3806181 1 NC_004342.2 hypothetical protein 3806181 1153176 LA_3834 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714014.1 3804754 D 189518 CDS YP_003573353.1 294828407 9006969 3806524..3806805 1 NC_004342.2 hypothetical protein 3806805 9006969 LA_3834a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573353.1 3806524 D 189518 CDS NP_714018.1 24216537 1153180 complement(3808009..3809349) 1 NC_004342.2 hypothetical protein 3809349 1153180 LA_3838 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714018.1 3808009 R 189518 CDS NP_714019.1 24216538 1153181 complement(3810185..3810730) 1 NC_004342.2 phospholipid binding protein 3810730 1153181 LA_3839 Leptospira interrogans serovar Lai str. 56601 phospholipid binding protein NP_714019.1 3810185 R 189518 CDS NP_714023.2 294828408 1153185 3812531..3814576 1 NC_004342.2 guanylate cyclase 3814576 1153185 LA_3843 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_714023.2 3812531 D 189518 CDS NP_714025.2 294828409 1153187 complement(3815129..3815755) 1 NC_004342.2 AcrR family transcriptional regulator 3815755 acrR 1153187 acrR Leptospira interrogans serovar Lai str. 56601 AcrR family transcriptional regulator NP_714025.2 3815129 R 189518 CDS NP_714026.1 24216545 1153188 complement(3815868..3819119) 1 NC_004342.2 cation/multidrug efflux pump 3819119 acrB 1153188 acrB Leptospira interrogans serovar Lai str. 56601 cation/multidrug efflux pump NP_714026.1 3815868 R 189518 CDS NP_714028.1 24216547 1153190 complement(3820815..3821531) 1 NC_004342.2 hypothetical protein 3821531 1153190 LA_3848 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714028.1 3820815 R 189518 CDS NP_714029.1 24216548 1153191 complement(3821541..3822275) 1 NC_004342.2 hypothetical protein 3822275 1153191 LA_3849 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714029.1 3821541 R 189518 CDS NP_714031.2 294828410 1153193 3822713..3823705 1 NC_004342.2 hydrolase 3823705 1153193 LA_3851 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_714031.2 3822713 D 189518 CDS NP_714033.1 24216552 1153195 3823893..3824762 1 NC_004342.2 hypothetical protein 3824762 1153195 LA_3853 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714033.1 3823893 D 189518 CDS NP_714034.1 24216553 1153196 complement(3825702..3826121) 1 NC_004342.2 hypothetical protein 3826121 1153196 LA_3854 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714034.1 3825702 R 189518 CDS NP_714035.2 294828411 1153197 complement(3826194..3827078) 1 NC_004342.2 pirin 3827078 1153197 LA_3855 Leptospira interrogans serovar Lai str. 56601 pirin NP_714035.2 3826194 R 189518 CDS NP_714036.1 24216555 1153198 3827150..3827623 1 NC_004342.2 hypothetical protein 3827623 1153198 LA_3856 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714036.1 3827150 D 189518 CDS NP_714041.1 24216560 1153203 complement(3830051..3830698) 1 NC_004342.2 hypothetical protein 3830698 1153203 LA_3861 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714041.1 3830051 R 189518 CDS NP_714042.1 24216561 1153204 complement(3830752..3831495) 1 NC_004342.2 hypothetical protein 3831495 1153204 LA_3862 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714042.1 3830752 R 189518 CDS NP_714043.2 294828413 1153205 complement(3831492..3832115) 1 NC_004342.2 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 3832115 coaE 1153205 coaE Leptospira interrogans serovar Lai str. 56601 dephospho-CoA kinase NP_714043.2 3831492 R 189518 CDS NP_714047.2 294828414 1153209 3833697..3834986 1 NC_004342.2 hypothetical protein 3834986 1153209 LA_3867 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714047.2 3833697 D 189518 CDS NP_714048.1 24216567 1153210 3835069..3836130 1 NC_004342.2 histidine kinase sensor protein 3836130 1153210 LA_3868 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_714048.1 3835069 D 189518 CDS NP_714049.1 24216568 1153211 3836127..3836798 1 NC_004342.2 response regulator containing a signal receiver domain and a DNA-binding domain 3836798 citB 1153211 citB Leptospira interrogans serovar Lai str. 56601 response regulator containing a signal receiver domain and a DNA-binding domain NP_714049.1 3836127 D 189518 CDS NP_714050.1 24216569 1153212 3837724..3839388 1 NC_004342.2 hypothetical protein 3839388 1153212 LA_3870 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714050.1 3837724 D 189518 CDS NP_714051.2 294828415 1153213 complement(3839998..3843111) 1 NC_004342.2 acriflavine resistance protein 3843111 1153213 LA_3871 Leptospira interrogans serovar Lai str. 56601 acriflavine resistance protein NP_714051.2 3839998 R 189518 CDS YP_003573354.1 294828416 9006970 complement(3843683..3843880) 1 NC_004342.2 hypothetical protein 3843880 9006970 LA_3871a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573354.1 3843683 R 189518 CDS NP_714052.1 24216571 1153214 3843765..3844718 1 NC_004342.2 periplasmic serine protease 3844718 sppA 1153214 sppA Leptospira interrogans serovar Lai str. 56601 periplasmic serine protease NP_714052.1 3843765 D 189518 CDS NP_714053.1 24216572 1153215 3844725..3845324 1 NC_004342.2 hypothetical protein 3845324 1153215 LA_3873 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714053.1 3844725 D 189518 CDS NP_714054.1 24216573 1153216 3845321..3846073 1 NC_004342.2 acid phosphatase 3846073 surE 1153216 surE Leptospira interrogans serovar Lai str. 56601 acid phosphatase NP_714054.1 3845321 D 189518 CDS NP_714056.1 24216575 1153218 3847014..3847721 1 NC_004342.2 TPR-repeat-containing protein 3847721 1153218 LA_3876 Leptospira interrogans serovar Lai str. 56601 TPR-repeat-containing protein NP_714056.1 3847014 D 189518 CDS NP_714057.2 294828417 1153219 complement(3848491..3849093) 1 NC_004342.2 hypothetical protein 3849093 1153219 LA_3877 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714057.2 3848491 R 189518 CDS NP_714059.1 24216578 1153221 3849182..3850096 1 NC_004342.2 nucleoside-diphosphate sugar epimerase 3850096 1153221 LA_3879 Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate sugar epimerase NP_714059.1 3849182 D 189518 CDS NP_714061.1 24216580 1153223 complement(3850597..3854202) 1 NC_004342.2 hypothetical protein 3854202 1153223 LA_3881 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714061.1 3850597 R 189518 CDS NP_714062.2 294828418 1153224 3855685..3856854 1 NC_004342.2 ISlin1 transposase 3856854 1153224 LA_3882 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714062.2 3855685 D 189518 CDS NP_714063.1 24216582 1153225 complement(3857069..3857686) 1 NC_004342.2 uracil-DNA glycosylase 3857686 1153225 LA_3883 Leptospira interrogans serovar Lai str. 56601 uracil-DNA glycosylase NP_714063.1 3857069 R 189518 CDS NP_714064.1 24216583 1153226 complement(3857700..3858143) 1 NC_004342.2 anti-sigma factor antagonist 3858143 1153226 LA_3884 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_714064.1 3857700 R 189518 CDS NP_714065.2 294828419 1153227 complement(3858140..3859291) 1 NC_004342.2 galactokinase 3859291 galK 1153227 galK Leptospira interrogans serovar Lai str. 56601 galactokinase NP_714065.2 3858140 R 189518 CDS NP_714068.1 24216587 1153230 3860707..3862044 1 NC_004342.2 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 3862044 pgi 1153230 pgi Leptospira interrogans serovar Lai str. 56601 glucose-6-phosphate isomerase NP_714068.1 3860707 D 189518 CDS NP_714070.1 24216589 1153232 3863586..3864464 1 NC_004342.2 hypothetical protein 3864464 1153232 LA_3890 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714070.1 3863586 D 189518 CDS NP_714072.1 24216591 1153234 complement(3864880..3865608) 1 NC_004342.2 nucleoside-diphosphate-sugar pyrophosphorylase 3865608 1153234 LA_3892 Leptospira interrogans serovar Lai str. 56601 nucleoside-diphosphate-sugar pyrophosphorylase NP_714072.1 3864880 R 189518 CDS NP_714073.1 24216592 1153235 complement(3865605..3866600) 1 NC_004342.2 Ser/Thr protein kinase-like phosphotransferase 3866600 1153235 LA_3893 Leptospira interrogans serovar Lai str. 56601 Ser/Thr protein kinase-like phosphotransferase NP_714073.1 3865605 R 189518 CDS NP_714074.1 24216593 1153236 complement(3866605..3868128) 1 NC_004342.2 histidine kinase/response regulator hybrid protein 3868128 1153236 LA_3894 Leptospira interrogans serovar Lai str. 56601 histidine kinase/response regulator hybrid protein NP_714074.1 3866605 R 189518 CDS NP_714075.1 24216594 1153237 complement(3868157..3870481) 1 NC_004342.2 histidine kinase sensor protein 3870481 1153237 LA_3895 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_714075.1 3868157 R 189518 CDS NP_714077.1 24216596 1153239 3871317..3872222 1 NC_004342.2 acyltransferase 3872222 1153239 LA_3897 Leptospira interrogans serovar Lai str. 56601 acyltransferase NP_714077.1 3871317 D 189518 CDS NP_714078.2 294828420 1153240 complement(3872919..3874088) 1 NC_004342.2 ISlin1 transposase 3874088 1153240 LA_3898 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714078.2 3872919 R 189518 CDS NP_714079.1 24216598 1153241 complement(3875180..3875563) 1 NC_004342.2 ISlin1 transposase 3875563 1153241 LA_3899 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714079.1 3875180 R 189518 CDS NP_714080.2 294828421 1153242 complement(3875532..3875864) 1 NC_004342.2 ISlin1 transposase 3875864 1153242 LA_3900 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714080.2 3875532 R 189518 CDS NP_714083.1 24216602 1153245 complement(3877015..3877881) 1 NC_004342.2 metallo-beta-lactamase superfamily hydrolase 3877881 1153245 LA_3903 Leptospira interrogans serovar Lai str. 56601 metallo-beta-lactamase superfamily hydrolase NP_714083.1 3877015 R 189518 CDS NP_714085.1 24216604 1153247 3878888..3880096 1 NC_004342.2 pyridoxal phosphate-dependent aminotransferase 3880096 wecE 1153247 wecE Leptospira interrogans serovar Lai str. 56601 pyridoxal phosphate-dependent aminotransferase NP_714085.1 3878888 D 189518 CDS NP_714087.1 24216606 1153249 complement(3881354..3881755) 1 NC_004342.2 hypothetical protein 3881755 1153249 LA_3907 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714087.1 3881354 R 189518 CDS NP_714089.1 24216608 1153251 3882411..3883925 1 NC_004342.2 signal transduction protein 3883925 1153251 LA_3909 Leptospira interrogans serovar Lai str. 56601 signal transduction protein NP_714089.1 3882411 D 189518 CDS NP_714090.1 24216609 1153252 complement(3884521..3885393) 1 NC_004342.2 hypothetical protein 3885393 1153252 LA_3910 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714090.1 3884521 R 189518 CDS NP_714091.2 294828422 1153253 3885470..3886030 1 NC_004342.2 hypothetical protein 3886030 1153253 LA_3911 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714091.2 3885470 D 189518 CDS NP_714092.1 24216611 1153254 3886081..3886956 1 NC_004342.2 hypothetical protein 3886956 1153254 LA_3912 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714092.1 3886081 D 189518 CDS NP_714093.1 24216612 1153255 complement(3887604..3888170) 1 NC_004342.2 hypothetical protein 3888170 1153255 LA_3913 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714093.1 3887604 R 189518 CDS NP_714095.2 294828423 1153257 3889582..3890736 1 NC_004342.2 transcriptional regulator 3890736 1153257 LA_3914 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_714095.2 3889582 D 189518 CDS NP_714096.2 294828424 1153258 complement(3892271..3893077) 1 NC_004342.2 hypothetical protein 3893077 1153258 LA_3916 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714096.2 3892271 R 189518 CDS NP_714097.1 24216616 1153259 complement(3893350..3893859) 1 NC_004342.2 hypothetical protein 3893859 1153259 LA_3917 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714097.1 3893350 R 189518 CDS NP_714098.1 24216617 1153260 3893970..3896117 1 NC_004342.2 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 3896117 metG 1153260 metG Leptospira interrogans serovar Lai str. 56601 methionyl-tRNA synthetase NP_714098.1 3893970 D 189518 CDS NP_714101.1 24216620 1153263 3897083..3899713 1 NC_004342.2 UTP:GlnB (protein PII) uridylyltransferase 3899713 glnD 1153263 glnD Leptospira interrogans serovar Lai str. 56601 UTP:GlnB (protein PII) uridylyltransferase NP_714101.1 3897083 D 189518 CDS NP_714102.1 24216621 1153264 complement(3899757..3900302) 1 NC_004342.2 hypothetical protein 3900302 1153264 LA_3922 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714102.1 3899757 R 189518 CDS NP_714103.1 24216622 1153265 complement(3900318..3901052) 1 NC_004342.2 hypothetical protein 3901052 1153265 LA_3923 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714103.1 3900318 R 189518 CDS NP_714104.1 24216623 1153266 complement(3901525..3902490) 1 NC_004342.2 NAD(P)H steroid dehydrogenase 3902490 1153266 LA_3924 Leptospira interrogans serovar Lai str. 56601 NAD(P)H steroid dehydrogenase NP_714104.1 3901525 R 189518 CDS NP_714106.1 24216625 1153268 3903454..3906621 1 NC_004342.2 cation/multidrug efflux pump 3906621 acrB 1153268 acrB Leptospira interrogans serovar Lai str. 56601 cation/multidrug efflux pump NP_714106.1 3903454 D 189518 CDS NP_714107.2 294828425 1153269 3907408..3909279 1 NC_004342.2 TolC family protein 3909279 1153269 LA_3927 Leptospira interrogans serovar Lai str. 56601 TolC family protein NP_714107.2 3907408 D 189518 CDS NP_714108.2 294828426 1153270 3909349..3911109 1 NC_004342.2 acyl-CoA dehydrogenase 3911109 caiA 1153270 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_714108.2 3909349 D 189518 CDS NP_714109.1 24216628 1153271 3911970..3912953 1 NC_004342.2 response regulator with GGDEF domain 3912953 1153271 LA_3929 Leptospira interrogans serovar Lai str. 56601 response regulator with GGDEF domain NP_714109.1 3911970 D 189518 CDS NP_714110.1 24216629 1153272 complement(3913172..3914164) 1 NC_004342.2 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 3914164 murB 1153272 murB Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylenolpyruvoylglucosamine reductase NP_714110.1 3913172 R 189518 CDS NP_714113.1 24216632 1153275 complement(3914856..3915056) 1 NC_004342.2 hypothetical protein 3915056 1153275 LA_3933 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714113.1 3914856 R 189518 CDS NP_714114.1 24216633 1153276 3915137..3915394 1 NC_004342.2 hypothetical protein 3915394 1153276 LA_3934 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714114.1 3915137 D 189518 CDS NP_714115.1 24216634 1153282 complement(3915530..3916216) 1 NC_004342.2 DNA/pantothenate metabolism flavoprotein 3916216 dfp 1153282 dfp Leptospira interrogans serovar Lai str. 56601 DNA/pantothenate metabolism flavoprotein NP_714115.1 3915530 R 189518 CDS NP_714116.1 24216635 1153278 complement(3916233..3916775) 1 NC_004342.2 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 3916775 1153278 LA_3936 Leptospira interrogans serovar Lai str. 56601 phosphopantothenoylcysteine decarboxylase NP_714116.1 3916233 R 189518 CDS NP_714117.1 24216636 1153279 complement(3916791..3918125) 1 NC_004342.2 hemolysin-like protein 3918125 tlyC 1153279 tlyC Leptospira interrogans serovar Lai str. 56601 hemolysin-like protein NP_714117.1 3916791 R 189518 CDS NP_714118.1 24216637 1153280 complement(3918345..3920930) 1 NC_004342.2 hypothetical protein 3920930 1153280 LA_3938 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714118.1 3918345 R 189518 CDS NP_714119.1 24216638 1153281 complement(3920936..3921943) 1 NC_004342.2 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3921943 gpsA 1153281 gpsA Leptospira interrogans serovar Lai str. 56601 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase NP_714119.1 3920936 R 189518 CDS NP_714120.1 24216639 9006975 3922072..3922758 1 NC_004342.2 hypothetical protein 3922758 9006975 LA_3940 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714120.1 3922072 D 189518 CDS NP_714122.2 294828427 1153284 3922870..3923871 1 NC_004342.2 phosphoesterase 3923871 1153284 LA_3941 Leptospira interrogans serovar Lai str. 56601 phosphoesterase NP_714122.2 3922870 D 189518 CDS NP_714123.1 24216642 1153285 3923874..3924551 1 NC_004342.2 hypothetical protein 3924551 1153285 LA_3943 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714123.1 3923874 D 189518 CDS NP_714124.1 24216643 1153286 3924548..3924967 1 NC_004342.2 hypothetical protein 3924967 1153286 LA_3944 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714124.1 3924548 D 189518 CDS NP_714125.1 24216644 1153287 3924948..3927122 1 NC_004342.2 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3927122 recG 1153287 recG Leptospira interrogans serovar Lai str. 56601 ATP-dependent DNA helicase RecG NP_714125.1 3924948 D 189518 CDS NP_714126.1 24216645 1153288 complement(3928609..3928956) 1 NC_004342.2 hypothetical protein 3928956 1153288 LA_3946 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714126.1 3928609 R 189518 CDS NP_714127.1 24216646 1153289 3929157..3929891 1 NC_004342.2 D-alanyl-D-alanine carboxypeptidase 3929891 1153289 LA_3947 Leptospira interrogans serovar Lai str. 56601 D-alanyl-D-alanine carboxypeptidase NP_714127.1 3929157 D 189518 CDS NP_714128.1 24216647 1153290 complement(3929892..3930863) 1 NC_004342.2 UDP-glucose 4-epimerase 3930863 galE 1153290 galE Leptospira interrogans serovar Lai str. 56601 UDP-glucose 4-epimerase NP_714128.1 3929892 R 189518 CDS NP_714129.1 24216648 1153291 complement(3930860..3931639) 1 NC_004342.2 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 3931639 lpxA 1153291 lpxA Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylglucosamine acyltransferase NP_714129.1 3930860 R 189518 CDS NP_714130.1 24216649 1153292 3931786..3932133 1 NC_004342.2 hypothetical protein 3932133 1153292 LA_3950 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714130.1 3931786 D 189518 CDS NP_714132.1 24216651 1153294 3932503..3933435 1 NC_004342.2 Fic family protein 3933435 1153294 LA_3952 Leptospira interrogans serovar Lai str. 56601 Fic family protein NP_714132.1 3932503 D 189518 CDS YP_003573355.1 294828428 9006976 3934493..3934705 1 NC_004342.2 ISlin1 transposase 3934705 9006976 LA_3952a Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase YP_003573355.1 3934493 D 189518 CDS NP_714134.2 294828429 1153296 3934702..3935307 1 NC_004342.2 ISlin1 transposase 3935307 1153296 LA_3954 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714134.2 3934702 D 189518 CDS NP_714135.2 294828430 1153297 3935313..3935672 1 NC_004342.2 ISlin1 transposase 3935672 1153297 LA_3955 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714135.2 3935313 D 189518 CDS NP_714136.2 294828431 1153298 3935901..3937070 1 NC_004342.2 ISlin1 transposase 3937070 1153298 LA_3956 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714136.2 3935901 D 189518 CDS NP_714137.1 24216656 1153299 complement(3937527..3938648) 1 NC_004342.2 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase 3938648 1153299 LA_3957 Leptospira interrogans serovar Lai str. 56601 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase NP_714137.1 3937527 R 189518 CDS NP_714138.1 24216657 1153300 complement(3938723..3939520) 1 NC_004342.2 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 3939520 panB 1153300 panB Leptospira interrogans serovar Lai str. 56601 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_714138.1 3938723 R 189518 CDS NP_714139.1 24216658 1153301 complement(3939504..3939953) 1 NC_004342.2 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 3939953 folK 1153301 folK Leptospira interrogans serovar Lai str. 56601 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase NP_714139.1 3939504 R 189518 CDS NP_714140.1 24216659 1153302 complement(3939950..3940807) 1 NC_004342.2 DNA replication protein DnaC 3940807 dnaC 1153302 dnaC Leptospira interrogans serovar Lai str. 56601 DNA replication protein DnaC NP_714140.1 3939950 R 189518 CDS NP_714141.2 294828432 1153303 3941503..3942414 1 NC_004342.2 hypothetical protein 3942414 1153303 LA_3961 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714141.2 3941503 D 189518 CDS NP_714142.1 24216661 1153304 3943268..3943666 1 NC_004342.2 hypothetical protein 3943666 1153304 LA_3962 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714142.1 3943268 D 189518 CDS NP_714144.1 24216663 1153306 complement(3944361..3945383) 1 NC_004342.2 GDP-mannose 4,6-dehydratase 3945383 gmd 1153306 gmd Leptospira interrogans serovar Lai str. 56601 GDP-mannose 4,6-dehydratase NP_714144.1 3944361 R 189518 CDS NP_714145.1 24216664 1153307 complement(3945427..3946848) 1 NC_004342.2 Na+-driven multidrug efflux pump 3946848 norM 1153307 norM Leptospira interrogans serovar Lai str. 56601 Na+-driven multidrug efflux pump NP_714145.1 3945427 R 189518 CDS NP_714146.1 24216665 1153308 complement(3947287..3947814) 1 NC_004342.2 hypothetical protein 3947814 1153308 LA_3966 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714146.1 3947287 R 189518 CDS NP_714149.1 24216668 1153311 3948586..3949911 1 NC_004342.2 adenosine/AMP deaminase 3949911 1153311 LA_3969 Leptospira interrogans serovar Lai str. 56601 adenosine/AMP deaminase NP_714149.1 3948586 D 189518 CDS NP_714150.1 24216669 1153312 3950077..3950994 1 NC_004342.2 hypothetical protein 3950994 1153312 LA_3970 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714150.1 3950077 D 189518 CDS NP_714151.1 24216670 1153313 3950994..3952793 1 NC_004342.2 potassium uptake transporter 3952793 trkG 1153313 trkG Leptospira interrogans serovar Lai str. 56601 potassium uptake transporter NP_714151.1 3950994 D 189518 CDS NP_714152.1 24216671 1153314 3952806..3953516 1 NC_004342.2 potassium uptake system, NAD-binding component 3953516 1153314 LA_3972 Leptospira interrogans serovar Lai str. 56601 potassium uptake system, NAD-binding component NP_714152.1 3952806 D 189518 CDS NP_714153.2 294828433 1153315 complement(3953501..3954562) 1 NC_004342.2 aldo/keto reductase 3954562 tas 1153315 tas Leptospira interrogans serovar Lai str. 56601 aldo/keto reductase NP_714153.2 3953501 R 189518 CDS NP_714154.1 24216673 1153316 3955050..3956252 1 NC_004342.2 exonuclease 3956252 1153316 LA_3974 Leptospira interrogans serovar Lai str. 56601 exonuclease NP_714154.1 3955050 D 189518 CDS NP_714155.1 24216674 1153317 complement(3956278..3956565) 1 NC_004342.2 acylphosphatase 3956565 acyP 1153317 acyP Leptospira interrogans serovar Lai str. 56601 acylphosphatase NP_714155.1 3956278 R 189518 CDS NP_714156.1 24216675 1153318 complement(3956555..3956992) 1 NC_004342.2 bacterial globin-like protein 3956992 1153318 LA_3976 Leptospira interrogans serovar Lai str. 56601 bacterial globin-like protein NP_714156.1 3956555 R 189518 CDS NP_714157.1 24216676 1153319 complement(3956992..3957480) 1 NC_004342.2 NTP pyrophosphohydrolase 3957480 1153319 LA_3977 Leptospira interrogans serovar Lai str. 56601 NTP pyrophosphohydrolase NP_714157.1 3956992 R 189518 CDS NP_714158.1 24216677 1153320 3958026..3958457 1 NC_004342.2 lysine methyltransferase 3958457 1153320 LA_3978 Leptospira interrogans serovar Lai str. 56601 lysine methyltransferase NP_714158.1 3958026 D 189518 CDS NP_714160.1 24216679 1153322 complement(3958880..3959668) 1 NC_004342.2 glycerophosphodiester phosphodiesterase 3959668 ugpQ 1153322 ugpQ Leptospira interrogans serovar Lai str. 56601 glycerophosphodiester phosphodiesterase NP_714160.1 3958880 R 189518 CDS NP_714162.1 24216681 1153324 complement(3959803..3960186) 1 NC_004342.2 hypothetical protein 3960186 1153324 LA_3982 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714162.1 3959803 R 189518 CDS NP_714163.2 294828434 1153325 3960961..3962130 1 NC_004342.2 ISlin1 transposase 3962130 1153325 LA_3983 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714163.2 3960961 D 189518 CDS NP_714165.1 24216684 1153327 complement(3962559..3963659) 1 NC_004342.2 membrane-bound lytic murein transglycosylase 3963659 1153327 LA_3985 Leptospira interrogans serovar Lai str. 56601 membrane-bound lytic murein transglycosylase NP_714165.1 3962559 R 189518 CDS NP_714166.1 24216685 1153328 complement(3963762..3965366) 1 NC_004342.2 transcriptional regulator 3965366 1153328 LA_3986 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_714166.1 3963762 R 189518 CDS NP_714167.2 294828435 1153329 complement(3965948..3966433) 1 NC_004342.2 hypothetical protein 3966433 1153329 LA_3987 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714167.2 3965948 R 189518 CDS NP_714168.2 294828436 1153330 complement(3967392..3968765) 1 NC_004342.2 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 3968765 1153330 LA_3988 Leptospira interrogans serovar Lai str. 56601 potassium/proton antiporter NP_714168.2 3967392 R 189518 CDS NP_714170.1 24216689 1153332 complement(3969338..3969553) 1 NC_004342.2 hypothetical protein 3969553 1153332 LA_3990 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714170.1 3969338 R 189518 CDS NP_714171.2 294828437 1153333 complement(3969575..3970015) 1 NC_004342.2 acetyltransferase 3970015 1153333 LA_3991 Leptospira interrogans serovar Lai str. 56601 acetyltransferase NP_714171.2 3969575 R 189518 CDS NP_714173.1 24216692 1153335 complement(3970700..3971986) 1 NC_004342.2 hypothetical protein 3971986 1153335 LA_3993 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714173.1 3970700 R 189518 CDS NP_714174.1 24216693 1153336 3972094..3973791 1 NC_004342.2 Fe-S oxidoreductase 3973791 1153336 LA_3994 Leptospira interrogans serovar Lai str. 56601 Fe-S oxidoreductase NP_714174.1 3972094 D 189518 CDS NP_714175.2 294828438 1153337 complement(3973917..3976331) 1 NC_004342.2 histidine kinase/response regulator hybrid protein 3976331 1153337 LA_3996 Leptospira interrogans serovar Lai str. 56601 histidine kinase/response regulator hybrid protein NP_714175.2 3973917 R 189518 CDS NP_714177.1 24216696 1153339 complement(3976739..3977818) 1 NC_004342.2 GTPase 3977818 1153339 LA_3997 Leptospira interrogans serovar Lai str. 56601 GTPase NP_714177.1 3976739 R 189518 CDS NP_714178.1 24216697 1153340 3978784..3982191 1 NC_004342.2 cholesterol oxidase 3982191 1153340 LA_3998 Leptospira interrogans serovar Lai str. 56601 cholesterol oxidase NP_714178.1 3978784 D 189518 CDS NP_714179.1 24216698 1153341 3982238..3983806 1 NC_004342.2 choline dehydrogenase 3983806 1153341 LA_3999 Leptospira interrogans serovar Lai str. 56601 choline dehydrogenase NP_714179.1 3982238 D 189518 CDS NP_714180.2 294828439 1153342 3984127..3984837 1 NC_004342.2 hypothetical protein 3984837 1153342 LA_4000 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714180.2 3984127 D 189518 CDS NP_714183.1 24216702 1153345 complement(3985775..3986284) 1 NC_004342.2 hypothetical protein 3986284 1153345 LA_4003 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714183.1 3985775 R 189518 CDS NP_714184.2 294828440 1153346 3986892..3988424 1 NC_004342.2 sphingomyelinase C precursor 3988424 1153346 LA_4004 Leptospira interrogans serovar Lai str. 56601 sphingomyelinase C precursor NP_714184.2 3986892 D 189518 CDS NP_714186.1 24216705 1153348 3988785..3989435 1 NC_004342.2 hypothetical protein 3989435 1153348 LA_4005 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714186.1 3988785 D 189518 CDS YP_003573356.1 294828441 9006977 3989493..3989906 1 NC_004342.2 hypothetical protein 3989906 9006977 LA_4005a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573356.1 3989493 D 189518 CDS NP_714188.1 24216707 1153350 complement(3990765..3994955) 1 NC_004342.2 guanylate cyclase 3994955 1153350 LA_4008 Leptospira interrogans serovar Lai str. 56601 guanylate cyclase NP_714188.1 3990765 R 189518 CDS NP_714189.1 24216708 1153351 complement(3995263..3996987) 1 NC_004342.2 cholesterol oxidase precursor 3996987 1153351 LA_4009 Leptospira interrogans serovar Lai str. 56601 cholesterol oxidase precursor NP_714189.1 3995263 R 189518 CDS NP_714190.1 24216709 1153352 complement(3997016..3997462) 1 NC_004342.2 hypothetical protein 3997462 1153352 LA_4010 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714190.1 3997016 R 189518 CDS NP_714191.2 294828442 1153353 complement(3997447..3998460) 1 NC_004342.2 hypothetical protein 3998460 1153353 LA_4011 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714191.2 3997447 R 189518 CDS NP_714193.1 24216712 1153355 3999659..4000585 1 NC_004342.2 Co/Zn/Cd efflux pump 4000585 czcD 1153355 czcD Leptospira interrogans serovar Lai str. 56601 Co/Zn/Cd efflux pump NP_714193.1 3999659 D 189518 CDS NP_714195.2 294828443 1153357 complement(4001072..4001578) 1 NC_004342.2 PaaI thioesterase-like protein 4001578 paaI 1153357 paaI Leptospira interrogans serovar Lai str. 56601 PaaI thioesterase-like protein NP_714195.2 4001072 R 189518 CDS NP_714197.1 24216716 1153359 complement(4002111..4002743) 1 NC_004342.2 penicillin-binding protein 4002743 1153359 LA_4017 Leptospira interrogans serovar Lai str. 56601 penicillin-binding protein NP_714197.1 4002111 R 189518 CDS NP_714199.1 24216718 1153361 complement(4003191..4003859) 1 NC_004342.2 riboflavin-specific deaminase/reductase 4003859 ribD 1153361 ribD Leptospira interrogans serovar Lai str. 56601 riboflavin-specific deaminase/reductase NP_714199.1 4003191 R 189518 CDS NP_714200.2 294828444 1153362 complement(4003856..4004041) 1 NC_004342.2 bacterioferritin-associated ferredoxin 4004041 1153362 LA_4021 Leptospira interrogans serovar Lai str. 56601 bacterioferritin-associated ferredoxin NP_714200.2 4003856 R 189518 CDS NP_714202.2 294828445 1153364 4004353..4005165 1 NC_004342.2 MFS transporter permease 4005165 1153364 LA_4022 Leptospira interrogans serovar Lai str. 56601 MFS transporter permease NP_714202.2 4004353 D 189518 CDS NP_714203.1 24216722 1153365 4005687..4005896 1 NC_004342.2 hypothetical protein 4005896 1153365 LA_4023 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714203.1 4005687 D 189518 CDS NP_714205.2 294828446 1153367 complement(4006643..4007437) 1 NC_004342.2 hypothetical protein 4007437 1153367 LA_4025 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714205.2 4006643 R 189518 CDS NP_714206.1 24216725 1153368 4007482..4008750 1 NC_004342.2 hypothetical protein 4008750 1153368 LA_4026 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714206.1 4007482 D 189518 CDS NP_714207.1 24216726 1153369 4008824..4009408 1 NC_004342.2 hypothetical protein 4009408 1153369 LA_4027 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714207.1 4008824 D 189518 CDS NP_714210.1 24216729 1153372 4010435..4011118 1 NC_004342.2 hypothetical protein 4011118 1153372 LA_4030 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714210.1 4010435 D 189518 CDS NP_714212.2 294828447 1153374 4011968..4012525 1 NC_004342.2 hypothetical protein 4012525 1153374 LA_4032 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714212.2 4011968 D 189518 CDS NP_714214.1 24216733 1153376 complement(4013491..4014060) 1 NC_004342.2 carbonic anhydrase/acetyltransferase 4014060 paaY 1153376 paaY Leptospira interrogans serovar Lai str. 56601 carbonic anhydrase/acetyltransferase NP_714214.1 4013491 R 189518 CDS NP_714215.1 24216734 1153377 complement(4014614..4017040) 1 NC_004342.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 4017040 pheT 1153377 pheT Leptospira interrogans serovar Lai str. 56601 phenylalanyl-tRNA synthetase subunit beta NP_714215.1 4014614 R 189518 CDS NP_714216.1 24216735 1153378 complement(4017119..4019965) 1 NC_004342.2 ATP-dependent RNA helicase 4019965 1153378 LA_4036 Leptospira interrogans serovar Lai str. 56601 ATP-dependent RNA helicase NP_714216.1 4017119 R 189518 CDS NP_714217.2 294828448 1153379 complement(4019966..4020679) 1 NC_004342.2 organic radical activating enzyme 4020679 1153379 LA_4037 Leptospira interrogans serovar Lai str. 56601 organic radical activating enzyme NP_714217.2 4019966 R 189518 CDS NP_714219.2 294828449 1153381 4021174..4022076 1 NC_004342.2 lauroyl/myristoyl acyltransferase 4022076 htrB 1153381 htrB Leptospira interrogans serovar Lai str. 56601 lauroyl/myristoyl acyltransferase NP_714219.2 4021174 D 189518 CDS NP_714220.1 24216739 1153382 complement(4022952..4023488) 1 NC_004342.2 inorganic pyrophosphatase 4023488 ppa 1153382 ppa Leptospira interrogans serovar Lai str. 56601 inorganic pyrophosphatase NP_714220.1 4022952 R 189518 CDS NP_714221.1 24216740 1153383 complement(4023546..4024877) 1 NC_004342.2 glycerol-3-phosphate antiporter 4024877 uhpC 1153383 uhpC Leptospira interrogans serovar Lai str. 56601 glycerol-3-phosphate antiporter NP_714221.1 4023546 R 189518 CDS NP_714222.2 294828450 1153384 complement(4024972..4025163) 1 NC_004342.2 hypothetical protein 4025163 1153384 LA_4042 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714222.2 4024972 R 189518 CDS NP_714224.2 294828451 1153386 4025874..4026530 1 NC_004342.2 hypothetical protein 4026530 1153386 LA_4044 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714224.2 4025874 D 189518 CDS NP_714226.1 24216745 1153388 4028727..4030535 1 NC_004342.2 hypothetical protein 4030535 1153388 LA_4046 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714226.1 4028727 D 189518 CDS NP_714230.2 294828452 1153392 4031153..4032703 1 NC_004342.2 DEAD/DEAH box helicase 4032703 srmB 1153392 srmB Leptospira interrogans serovar Lai str. 56601 DEAD/DEAH box helicase NP_714230.2 4031153 D 189518 CDS NP_714231.1 24216750 1153393 4032830..4034143 1 NC_004342.2 hypothetical protein 4034143 1153393 LA_4051 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714231.1 4032830 D 189518 CDS NP_714232.1 24216751 1153394 complement(4035131..4035931) 1 NC_004342.2 short-chain dehydrogenase 4035931 dltE 1153394 dltE Leptospira interrogans serovar Lai str. 56601 short-chain dehydrogenase NP_714232.1 4035131 R 189518 CDS NP_714233.1 24216752 1153395 4036082..4036573 1 NC_004342.2 hypothetical protein 4036573 1153395 LA_4053 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714233.1 4036082 D 189518 CDS NP_714235.2 294828453 1153397 4036972..4037883 1 NC_004342.2 malate permease 4037883 1153397 LA_4055 Leptospira interrogans serovar Lai str. 56601 malate permease NP_714235.2 4036972 D 189518 CDS NP_714236.2 294828454 1153398 4037967..4038983 1 NC_004342.2 ankyrin repeat-containing protein 4038983 arp 1153398 arp Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_714236.2 4037967 D 189518 CDS NP_714238.1 24216757 1153400 complement(4040014..4040571) 1 NC_004342.2 lysine decarboxylase-like protein 4040571 1153400 LA_4058 Leptospira interrogans serovar Lai str. 56601 lysine decarboxylase-like protein NP_714238.1 4040014 R 189518 CDS NP_714239.2 294828455 1153401 4040726..4041994 1 NC_004342.2 hypothetical protein 4041994 1153401 LA_4059 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714239.2 4040726 D 189518 CDS NP_714242.1 24216761 1153404 complement(4042707..4043228) 1 NC_004342.2 hypothetical protein 4043228 1153404 LA_4062 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714242.1 4042707 R 189518 CDS NP_714243.3 294828456 1153405 4043300..4044196 1 NC_004342.2 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 4044196 mazG 1153405 mazG Leptospira interrogans serovar Lai str. 56601 nucleoside triphosphate pyrophosphohydrolase NP_714243.3 4043300 D 189518 CDS NP_714244.2 294828457 1153406 4044193..4044573 1 NC_004342.2 hypothetical protein 4044573 1153406 LA_4064 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714244.2 4044193 D 189518 CDS NP_714245.1 24216764 1153407 4044570..4045340 1 NC_004342.2 two-component response regulator 4045340 1153407 LA_4065 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_714245.1 4044570 D 189518 CDS NP_714246.1 24216765 1153408 complement(4045337..4046011) 1 NC_004342.2 hypothetical protein 4046011 1153408 LA_4066 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714246.1 4045337 R 189518 CDS NP_714247.1 24216766 1153409 complement(4046106..4047302) 1 NC_004342.2 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 4047302 icd 1153409 icd Leptospira interrogans serovar Lai str. 56601 isocitrate dehydrogenase NP_714247.1 4046106 R 189518 CDS NP_714248.1 24216767 1153410 complement(4047371..4048024) 1 NC_004342.2 hypothetical protein 4048024 1153410 LA_4068 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714248.1 4047371 R 189518 CDS NP_714249.1 24216768 1153411 4048208..4048654 1 NC_004342.2 hypothetical protein 4048654 1153411 LA_4069 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714249.1 4048208 D 189518 CDS NP_714250.1 24216769 1153412 4048686..4049801 1 NC_004342.2 hypothetical protein 4049801 1153412 LA_4070 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714250.1 4048686 D 189518 CDS NP_714251.2 294828458 1153413 4050162..4051331 1 NC_004342.2 ISlin1 transposase 4051331 1153413 LA_4071 Leptospira interrogans serovar Lai str. 56601 ISlin1 transposase NP_714251.2 4050162 D 189518 CDS NP_714253.2 294828459 1153415 complement(4051919..4053307) 1 NC_004342.2 hypothetical protein 4053307 1153415 LA_4073 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714253.2 4051919 R 189518 CDS NP_714256.1 24216775 1153418 complement(4054406..4054894) 1 NC_004342.2 hypothetical protein 4054894 1153418 LA_4076 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714256.1 4054406 R 189518 CDS NP_714258.2 294828460 1153420 complement(4055043..4056872) 1 NC_004342.2 apolipoprotein n-acyltransferase 4056872 1153420 LA_4078 Leptospira interrogans serovar Lai str. 56601 apolipoprotein n-acyltransferase NP_714258.2 4055043 R 189518 CDS NP_714259.1 24216778 1153421 4057081..4058379 1 NC_004342.2 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4058379 murA 1153421 murA Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_714259.1 4057081 D 189518 CDS NP_714260.1 24216779 1153422 4058376..4059032 1 NC_004342.2 methylamine utilization ferredoxin-type protein 4059032 hycB 1153422 hycB Leptospira interrogans serovar Lai str. 56601 methylamine utilization ferredoxin-type protein NP_714260.1 4058376 D 189518 CDS NP_714261.1 24216780 1153423 4059074..4059445 1 NC_004342.2 hypothetical protein 4059445 1153423 LA_4081 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714261.1 4059074 D 189518 CDS NP_714262.1 24216781 1153424 complement(4060653..4061141) 1 NC_004342.2 hypothetical protein 4061141 1153424 LA_4082 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714262.1 4060653 R 189518 CDS NP_714263.1 24216782 1153425 complement(4061151..4061486) 1 NC_004342.2 hypothetical protein 4061486 1153425 LA_4083 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714263.1 4061151 R 189518 CDS NP_714264.2 294828461 1153426 complement(4061953..4062504) 1 NC_004342.2 hypothetical protein 4062504 1153426 LA_4084 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714264.2 4061953 R 189518 CDS NP_714265.1 24216784 1153427 complement(4062509..4063531) 1 NC_004342.2 Zn-dependent alcohol dehydrogenase 4063531 adhP 1153427 adhP Leptospira interrogans serovar Lai str. 56601 Zn-dependent alcohol dehydrogenase NP_714265.1 4062509 R 189518 CDS NP_714266.1 24216785 1153428 complement(4063528..4063854) 1 NC_004342.2 ferredoxin 4063854 1153428 LA_4086 Leptospira interrogans serovar Lai str. 56601 ferredoxin NP_714266.1 4063528 R 189518 CDS NP_714267.1 24216786 1153429 4064248..4064742 1 NC_004342.2 hypothetical protein 4064742 1153429 LA_4087 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714267.1 4064248 D 189518 CDS NP_714268.1 24216787 1153430 4064721..4065710 1 NC_004342.2 hypothetical protein 4065710 1153430 LA_4088 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714268.1 4064721 D 189518 CDS NP_714269.2 294828462 1153431 complement(4065719..4066489) 1 NC_004342.2 phenazine biosynthesis protein 4066489 1153431 LA_4089 Leptospira interrogans serovar Lai str. 56601 phenazine biosynthesis protein NP_714269.2 4065719 R 189518 CDS NP_714271.2 294828463 1153433 complement(4067555..4068895) 1 NC_004342.2 amidophosphoribosyltransferase 4068895 purF 1153433 purF Leptospira interrogans serovar Lai str. 56601 amidophosphoribosyltransferase NP_714271.2 4067555 R 189518 CDS NP_714272.2 294828464 1153434 4069069..4070235 1 NC_004342.2 ribonuclease D 4070235 rnd 1153434 rnd Leptospira interrogans serovar Lai str. 56601 ribonuclease D NP_714272.2 4069069 D 189518 CDS NP_714273.1 24216792 1153435 4070267..4070938 1 NC_004342.2 MutT/nudix family protein 4070938 1153435 LA_4093 Leptospira interrogans serovar Lai str. 56601 MutT/nudix family protein NP_714273.1 4070267 D 189518 CDS NP_714276.1 24216795 1153438 4072667..4072840 1 NC_004342.2 hypothetical protein 4072840 1153438 LA_4096 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714276.1 4072667 D 189518 CDS NP_714277.1 24216796 1153439 4072837..4073232 1 NC_004342.2 hypothetical protein 4073232 1153439 LA_4097 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714277.1 4072837 D 189518 CDS NP_714278.1 24216797 1153440 4073232..4073810 1 NC_004342.2 RNA polymerase ECF-type sigma factor 4073810 rpoE 1153440 rpoE Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_714278.1 4073232 D 189518 CDS NP_714279.1 24216798 1153441 4073794..4074165 1 NC_004342.2 hypothetical protein 4074165 1153441 LA_4099 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714279.1 4073794 D 189518 CDS NP_714280.1 24216799 1153442 4074162..4074608 1 NC_004342.2 hypothetical protein 4074608 1153442 LA_4100 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714280.1 4074162 D 189518 CDS NP_714283.1 24216802 1153445 4075917..4076618 1 NC_004342.2 response regulator 4076618 vicR 1153445 vicR Leptospira interrogans serovar Lai str. 56601 response regulator NP_714283.1 4075917 D 189518 CDS NP_714284.1 24216803 1153446 4076608..4077999 1 NC_004342.2 two-component sensor histidine kinase VicK 4077999 vicK 1153446 vicK Leptospira interrogans serovar Lai str. 56601 two-component sensor histidine kinase VicK NP_714284.1 4076608 D 189518 CDS NP_714285.2 294828465 1153447 4078074..4079225 1 NC_004342.2 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 4079225 argJ 1153447 argJ Leptospira interrogans serovar Lai str. 56601 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein NP_714285.2 4078074 D 189518 CDS NP_714286.1 24216805 1153448 4079206..4080510 1 NC_004342.2 hypothetical protein 4080510 1153448 LA_4106 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714286.1 4079206 D 189518 CDS NP_714287.1 24216806 1153449 4080507..4082885 1 NC_004342.2 serine phosphatase RsbU 4082885 1153449 LA_4107 Leptospira interrogans serovar Lai str. 56601 serine phosphatase RsbU NP_714287.1 4080507 D 189518 CDS NP_714288.1 24216807 1153450 complement(4083239..4083925) 1 NC_004342.2 hypothetical protein 4083925 1153450 LA_4108 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714288.1 4083239 R 189518 CDS NP_714289.1 24216808 1153451 complement(4084130..4085254) 1 NC_004342.2 hypothetical protein 4085254 1153451 LA_4109 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714289.1 4084130 R 189518 CDS NP_714290.1 24216809 1153452 complement(4085251..4085505) 1 NC_004342.2 hypothetical protein 4085505 1153452 LA_4110 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714290.1 4085251 R 189518 CDS YP_003573357.1 294828466 9006979 complement(4086535..4086762) 1 NC_004342.2 hypothetical protein 4086762 9006979 LA_4110a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573357.1 4086535 R 189518 CDS NP_714293.2 294828467 1153455 complement(4086841..4087143) 1 NC_004342.2 hypothetical protein 4087143 1153455 LA_4113 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714293.2 4086841 R 189518 CDS NP_714294.1 24216813 1153456 complement(4087217..4088740) 1 NC_004342.2 acetyl-CoA acetyltransferase 4088740 1153456 LA_4114 Leptospira interrogans serovar Lai str. 56601 acetyl-CoA acetyltransferase NP_714294.1 4087217 R 189518 CDS NP_714295.1 24216814 1153457 complement(4089017..4089466) 1 NC_004342.2 MaoC-like acyl dehydratase 4089466 maoC 1153457 maoC Leptospira interrogans serovar Lai str. 56601 MaoC-like acyl dehydratase NP_714295.1 4089017 R 189518 CDS NP_714297.1 24216816 1153459 complement(4090296..4091900) 1 NC_004342.2 acyl-CoA dehydrogenase 4091900 caiA 1153459 caiA Leptospira interrogans serovar Lai str. 56601 acyl-CoA dehydrogenase NP_714297.1 4090296 R 189518 CDS NP_714299.1 24216818 1153461 complement(4092929..4094974) 1 NC_004342.2 NAD dependent DNA ligase 4094974 lig 1153461 lig Leptospira interrogans serovar Lai str. 56601 NAD dependent DNA ligase NP_714299.1 4092929 R 189518 CDS NP_714300.1 24216819 1153462 complement(4094993..4095964) 1 NC_004342.2 M23 family metalloendopeptidase 4095964 nlpD 1153462 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_714300.1 4094993 R 189518 CDS NP_714301.1 24216820 1153463 complement(4096245..4096604) 1 NC_004342.2 hypothetical protein 4096604 1153463 LA_4121 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714301.1 4096245 R 189518 CDS NP_714302.1 24216821 1153464 complement(4096622..4097131) 1 NC_004342.2 RNA polymerase ECF-type sigma factor 4097131 rpoE 1153464 rpoE Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_714302.1 4096622 R 189518 CDS NP_714303.2 294828468 1153465 complement(4097139..4097684) 1 NC_004342.2 hypothetical protein 4097684 1153465 LA_4123 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714303.2 4097139 R 189518 CDS NP_714304.1 24216823 1153466 4097853..4098545 1 NC_004342.2 SanA-like protein 4098545 sanA 1153466 sanA Leptospira interrogans serovar Lai str. 56601 SanA-like protein NP_714304.1 4097853 D 189518 CDS NP_714306.2 294828469 1153468 complement(4099840..4100871) 1 NC_004342.2 two component system sensor histidine kinase 4100871 1153468 LA_4126 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase NP_714306.2 4099840 R 189518 CDS NP_714307.1 24216826 1153469 complement(4101178..4102308) 1 NC_004342.2 two component system sensor histidine kinase 4102308 1153469 LA_4127 Leptospira interrogans serovar Lai str. 56601 two component system sensor histidine kinase NP_714307.1 4101178 R 189518 CDS NP_714308.1 24216827 1153470 complement(4102704..4103048) 1 NC_004342.2 hypothetical protein 4103048 1153470 LA_4128 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714308.1 4102704 R 189518 CDS NP_714309.1 24216828 1153471 complement(4103045..4103557) 1 NC_004342.2 ankyrin repeat-containing protein 4103557 arp 1153471 arp Leptospira interrogans serovar Lai str. 56601 ankyrin repeat-containing protein NP_714309.1 4103045 R 189518 CDS NP_714310.1 24216829 1153472 4104096..4104623 1 NC_004342.2 transcriptional regulator 4104623 1153472 LA_4130 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_714310.1 4104096 D 189518 CDS NP_714311.1 24216830 1153473 4105182..4107161 1 NC_004342.2 peptidase-like protein 4107161 1153473 LA_4131 Leptospira interrogans serovar Lai str. 56601 peptidase-like protein NP_714311.1 4105182 D 189518 CDS NP_714313.1 24216832 1153475 4108134..4108661 1 NC_004342.2 Macro domain-containing protein 4108661 1153475 LA_4133 Leptospira interrogans serovar Lai str. 56601 Macro domain-containing protein NP_714313.1 4108134 D 189518 CDS NP_714315.2 294828470 1153477 complement(4109379..4111907) 1 NC_004342.2 hypothetical protein 4111907 1153477 LA_4135 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714315.2 4109379 R 189518 CDS NP_714317.1 24216836 1153479 complement(4114037..4114576) 1 NC_004342.2 NADPH-dependent FMN reductase 4114576 1153479 LA_4137 Leptospira interrogans serovar Lai str. 56601 NADPH-dependent FMN reductase NP_714317.1 4114037 R 189518 CDS NP_714318.1 24216837 1153480 4114883..4116193 1 NC_004342.2 3-hydroxyacyl-CoA dehydrogenase 4116193 fadB 1153480 fadB Leptospira interrogans serovar Lai str. 56601 3-hydroxyacyl-CoA dehydrogenase NP_714318.1 4114883 D 189518 CDS NP_714319.1 24216838 1153481 4116209..4117474 1 NC_004342.2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 4117474 1153481 LA_4139 Leptospira interrogans serovar Lai str. 56601 acetyl-CoA acetyltransferase NP_714319.1 4116209 D 189518 CDS NP_714320.1 24216839 1153482 4117477..4117914 1 NC_004342.2 hypothetical protein 4117914 1153482 LA_4140 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714320.1 4117477 D 189518 CDS NP_714322.1 24216841 1153484 complement(4118645..4119607) 1 NC_004342.2 hypothetical protein 4119607 1153484 LA_4142 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714322.1 4118645 R 189518 CDS YP_003573358.1 294828471 9006980 complement(4119890..4120090) 1 NC_004342.2 hypothetical protein 4120090 9006980 LA_4142a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573358.1 4119890 R 189518 CDS NP_714323.1 24216842 1153485 4120137..4121012 1 NC_004342.2 hypothetical protein 4121012 1153485 LA_4143 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714323.1 4120137 D 189518 CDS NP_714324.2 294828472 1153486 complement(4121079..4121450) 1 NC_004342.2 hypothetical protein 4121450 1153486 LA_4144 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714324.2 4121079 R 189518 CDS NP_714325.1 24216844 1153487 complement(4121404..4121622) 1 NC_004342.2 hypothetical protein 4121622 1153487 LA_4145 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714325.1 4121404 R 189518 CDS NP_714326.2 294828473 1153488 4122632..4123480 1 NC_004342.2 internalin G related protein 4123480 1153488 LA_4146 Leptospira interrogans serovar Lai str. 56601 internalin G related protein NP_714326.2 4122632 D 189518 CDS NP_714328.1 24216847 1153490 4124079..4124285 1 NC_004342.2 hypothetical protein 4124285 1153490 LA_4148 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714328.1 4124079 D 189518 CDS NP_714329.2 294828474 1153491 complement(4124837..4125214) 1 NC_004342.2 thioesterase 4125214 1153491 LA_4149 Leptospira interrogans serovar Lai str. 56601 thioesterase NP_714329.2 4124837 R 189518 CDS NP_714330.1 24216849 1153492 complement(4125252..4126277) 1 NC_004342.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 4126277 pheS 1153492 pheS Leptospira interrogans serovar Lai str. 56601 phenylalanyl-tRNA synthetase subunit alpha NP_714330.1 4125252 R 189518 CDS NP_714331.1 24216850 1153493 complement(4126274..4127671) 1 NC_004342.2 UDP-N-acetylmuramate--L-alanine ligase 4127671 murC 1153493 murC Leptospira interrogans serovar Lai str. 56601 UDP-N-acetylmuramate--L-alanine ligase NP_714331.1 4126274 R 189518 CDS NP_714332.1 24216851 1153494 complement(4127668..4128285) 1 NC_004342.2 hypothetical protein 4128285 1153494 LA_4152 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714332.1 4127668 R 189518 CDS NP_714333.1 24216852 1153495 complement(4128272..4129375) 1 NC_004342.2 hypothetical protein 4129375 1153495 LA_4153 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714333.1 4128272 R 189518 CDS NP_714334.2 294828475 1153496 complement(4129372..4131390) 1 NC_004342.2 hypothetical protein 4131390 1153496 LA_4154 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714334.2 4129372 R 189518 CDS NP_714335.1 24216854 1153497 complement(4131387..4132115) 1 NC_004342.2 ABC transporter permease 4132115 1153497 LA_4155 Leptospira interrogans serovar Lai str. 56601 ABC transporter permease NP_714335.1 4131387 R 189518 CDS NP_714336.1 24216855 1153498 complement(4132120..4133049) 1 NC_004342.2 ABC transporter ATP-binding protein 4133049 ccmA 1153498 ccmA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_714336.1 4132120 R 189518 CDS NP_714339.1 24216858 1153501 4134365..4135522 1 NC_004342.2 fatty acid synthase subunit beta 4135522 1153501 LA_4159 Leptospira interrogans serovar Lai str. 56601 fatty acid synthase subunit beta NP_714339.1 4134365 D 189518 CDS NP_714340.1 24216859 1153502 4135861..4137084 1 NC_004342.2 hypothetical protein 4137084 1153502 LA_4160 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714340.1 4135861 D 189518 CDS NP_714341.2 294828478 1153503 complement(4137413..4139788) 1 NC_004342.2 thermolysin 4139788 1153503 LA_4161 Leptospira interrogans serovar Lai str. 56601 thermolysin NP_714341.2 4137413 R 189518 CDS NP_714344.2 294828479 1153506 complement(4140827..4143088) 1 NC_004342.2 thermolysin 4143088 1153506 LA_4164 Leptospira interrogans serovar Lai str. 56601 thermolysin NP_714344.2 4140827 R 189518 CDS NP_714346.1 24216865 1153508 4144069..4145280 1 NC_004342.2 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 4145280 argG 1153508 argG Leptospira interrogans serovar Lai str. 56601 argininosuccinate synthase NP_714346.1 4144069 D 189518 CDS NP_714347.1 24216866 1153509 4145277..4145759 1 NC_004342.2 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4145759 coaD 1153509 coaD Leptospira interrogans serovar Lai str. 56601 phosphopantetheine adenylyltransferase NP_714347.1 4145277 D 189518 CDS NP_714348.1 24216867 1153510 4145769..4146182 1 NC_004342.2 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 4146182 ndk 1153510 ndk Leptospira interrogans serovar Lai str. 56601 nucleoside diphosphate kinase NP_714348.1 4145769 D 189518 CDS NP_714350.2 294828480 1153512 4146657..4146839 1 NC_004342.2 hypothetical protein 4146839 1153512 LA_4170 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714350.2 4146657 D 189518 CDS NP_714351.1 24216870 1153513 4147754..4149220 1 NC_004342.2 catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 4149220 leuB 1153513 leuB Leptospira interrogans serovar Lai str. 56601 isocitrate dehydrogenase NP_714351.1 4147754 D 189518 CDS NP_714352.2 294828481 1153514 4149496..4149864 1 NC_004342.2 hypothetical protein 4149864 1153514 LA_4172 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714352.2 4149496 D 189518 CDS NP_714353.2 294828482 1153515 complement(4150393..4150782) 1 NC_004342.2 receiver protein of a two-component response regulator 4150782 1153515 LA_4173 Leptospira interrogans serovar Lai str. 56601 receiver protein of a two-component response regulator NP_714353.2 4150393 R 189518 CDS NP_714354.2 294828483 1153516 complement(4150787..4152322) 1 NC_004342.2 histidine kinase sensor protein 4152322 1153516 LA_4174 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_714354.2 4150787 R 189518 CDS NP_714356.2 294828484 1153518 complement(4152842..4153075) 1 NC_004342.2 hypothetical protein 4153075 1153518 LA_4176 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714356.2 4152842 R 189518 CDS NP_714357.1 24216876 1153519 4153165..4153731 1 NC_004342.2 hypothetical protein 4153731 1153519 LA_4177 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714357.1 4153165 D 189518 CDS NP_714358.1 24216877 1153520 4153728..4155284 1 NC_004342.2 GMC oxidoreductase 4155284 1153520 LA_4178 Leptospira interrogans serovar Lai str. 56601 GMC oxidoreductase NP_714358.1 4153728 D 189518 CDS NP_714359.1 24216878 1153521 4155936..4156175 1 NC_004342.2 hypothetical protein 4156175 1153521 LA_4179 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714359.1 4155936 D 189518 CDS NP_714360.1 24216879 1153522 4156172..4157350 1 NC_004342.2 aminotransferase 4157350 1153522 LA_4180 Leptospira interrogans serovar Lai str. 56601 aminotransferase NP_714360.1 4156172 D 189518 CDS NP_714361.2 294828485 1153523 complement(4158364..4159350) 1 NC_004342.2 carboxypeptidase 4159350 1153523 LA_4181 Leptospira interrogans serovar Lai str. 56601 carboxypeptidase NP_714361.2 4158364 R 189518 CDS NP_714362.1 24216881 1153524 complement(4159365..4159778) 1 NC_004342.2 hypothetical protein 4159778 1153524 LA_4182 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714362.1 4159365 R 189518 CDS NP_714363.2 294828486 1153525 complement(4159790..4160440) 1 NC_004342.2 endoflagellar motor protein 4160440 1153525 LA_4183 Leptospira interrogans serovar Lai str. 56601 endoflagellar motor protein NP_714363.2 4159790 R 189518 CDS NP_714364.1 24216883 1153526 complement(4160515..4161165) 1 NC_004342.2 hypothetical protein 4161165 1153526 LA_4184 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714364.1 4160515 R 189518 CDS NP_714365.2 294828487 1153527 complement(4161162..4162259) 1 NC_004342.2 hypothetical protein 4162259 1153527 LA_4185 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714365.2 4161162 R 189518 CDS NP_714367.1 24216886 1153529 complement(4162681..4163208) 1 NC_004342.2 hypothetical protein 4163208 1153529 LA_4187 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714367.1 4162681 R 189518 CDS NP_714368.1 24216887 1153530 complement(4163345..4164205) 1 NC_004342.2 hypothetical protein 4164205 1153530 LA_4188 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714368.1 4163345 R 189518 CDS NP_714369.1 24216888 1153531 complement(4164207..4164794) 1 NC_004342.2 anti-sigma regulatory factor 4164794 1153531 LA_4189 Leptospira interrogans serovar Lai str. 56601 anti-sigma regulatory factor NP_714369.1 4164207 R 189518 CDS NP_714370.1 24216889 1153532 complement(4164867..4166432) 1 NC_004342.2 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 4166432 gltX 1153532 gltX Leptospira interrogans serovar Lai str. 56601 glutamyl-tRNA synthetase NP_714370.1 4164867 R 189518 CDS NP_714371.2 294828488 1153533 complement(4166429..4167235) 1 NC_004342.2 hypothetical protein 4167235 1153533 LA_4191 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714371.2 4166429 R 189518 CDS NP_714373.1 24216892 1153535 4167547..4168935 1 NC_004342.2 DNA gyrase subunit A 4168935 gyrA 1153535 gyrA Leptospira interrogans serovar Lai str. 56601 DNA gyrase subunit A NP_714373.1 4167547 D 189518 CDS NP_714374.1 24216893 1153536 4168932..4171067 1 NC_004342.2 DNA gyrase subunit B 4171067 1153536 LA_4194 Leptospira interrogans serovar Lai str. 56601 DNA gyrase subunit B NP_714374.1 4168932 D 189518 CDS NP_714375.1 24216894 1153537 4171128..4171601 1 NC_004342.2 hypothetical protein 4171601 1153537 LA_4195 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714375.1 4171128 D 189518 CDS NP_714376.1 24216895 1153538 4171885..4172736 1 NC_004342.2 hypothetical protein 4172736 1153538 LA_4196 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714376.1 4171885 D 189518 CDS NP_714378.2 294828489 1153540 complement(4172886..4173788) 1 NC_004342.2 hypothetical protein 4173788 1153540 LA_4198 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714378.2 4172886 R 189518 CDS NP_714379.1 24216898 1153541 4174173..4174376 1 NC_004342.2 hypothetical protein 4174376 1153541 LA_4199 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714379.1 4174173 D 189518 CDS NP_714380.1 24216899 1153542 complement(4174668..4176011) 1 NC_004342.2 L-amino acid oxidase 4176011 1153542 LA_4200 Leptospira interrogans serovar Lai str. 56601 L-amino acid oxidase NP_714380.1 4174668 R 189518 CDS NP_714382.1 24216901 1153544 4176775..4177344 1 NC_004342.2 hypothetical protein 4177344 1153544 LA_4202 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714382.1 4176775 D 189518 CDS NP_714383.1 24216902 1153545 4177489..4178328 1 NC_004342.2 hypothetical protein 4178328 1153545 LA_4203 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714383.1 4177489 D 189518 CDS NP_714384.1 24216903 1153546 4178489..4179523 1 NC_004342.2 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 4179523 cobT 1153546 cobT Leptospira interrogans serovar Lai str. 56601 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase NP_714384.1 4178489 D 189518 CDS NP_714385.1 24216904 1153547 4179520..4180317 1 NC_004342.2 cobalamin synthase 4180317 cobS 1153547 cobS Leptospira interrogans serovar Lai str. 56601 cobalamin synthase NP_714385.1 4179520 D 189518 CDS NP_714386.1 24216905 1153548 4180302..4180886 1 NC_004342.2 phosphoglycerate mutase 4180886 gpmB 1153548 gpmB Leptospira interrogans serovar Lai str. 56601 phosphoglycerate mutase NP_714386.1 4180302 D 189518 CDS NP_714387.2 294828490 1153549 4181485..4182519 1 NC_004342.2 hypothetical protein 4182519 1153549 LA_4207 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714387.2 4181485 D 189518 CDS NP_714388.1 24216907 1153550 complement(4182523..4184358) 1 NC_004342.2 hypothetical protein 4184358 1153550 LA_4208 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714388.1 4182523 R 189518 CDS NP_714389.1 24216908 1153551 complement(4184360..4186447) 1 NC_004342.2 hypothetical protein 4186447 1153551 LA_4209 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714389.1 4184360 R 189518 CDS NP_714390.1 24216909 1153552 complement(4187423..4189270) 1 NC_004342.2 chloride channel protein EriC 4189270 eriC 1153552 eriC Leptospira interrogans serovar Lai str. 56601 chloride channel protein EriC NP_714390.1 4187423 R 189518 CDS NP_714392.2 294828491 1153554 complement(4190091..4190819) 1 NC_004342.2 hypothetical protein 4190819 1153554 LA_4212 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714392.2 4190091 R 189518 CDS NP_714393.1 24216912 1153555 complement(4190864..4191775) 1 NC_004342.2 amino terminal protease 4191775 1153555 LA_4214 Leptospira interrogans serovar Lai str. 56601 amino terminal protease NP_714393.1 4190864 R 189518 CDS NP_714394.2 294828492 1153556 4191838..4192758 1 NC_004342.2 M23 family metalloendopeptidase 4192758 nlpD 1153556 nlpD Leptospira interrogans serovar Lai str. 56601 M23 family metalloendopeptidase NP_714394.2 4191838 D 189518 CDS NP_714395.1 24216914 1153557 4192751..4193827 1 NC_004342.2 strictosidine synthase 4193827 1153557 LA_4215 Leptospira interrogans serovar Lai str. 56601 strictosidine synthase NP_714395.1 4192751 D 189518 CDS NP_714396.2 294828493 1153558 complement(4193837..4195522) 1 NC_004342.2 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 4195522 cysI 1153558 cysI Leptospira interrogans serovar Lai str. 56601 sulfite reductase subunit beta NP_714396.2 4193837 R 189518 CDS NP_714397.1 24216916 1153559 complement(4195559..4196167) 1 NC_004342.2 siroheme synthase 4196167 cysG 1153559 cysG Leptospira interrogans serovar Lai str. 56601 siroheme synthase NP_714397.1 4195559 R 189518 CDS NP_714398.1 24216917 1153560 complement(4196157..4196996) 1 NC_004342.2 uroporphyrin-III C-methyltransferase 4196996 1153560 LA_4218 Leptospira interrogans serovar Lai str. 56601 uroporphyrin-III C-methyltransferase NP_714398.1 4196157 R 189518 CDS NP_714399.1 24216918 1153561 complement(4197000..4198250) 1 NC_004342.2 sulfate adenylyltransferase subunit 1 4198250 cysN 1153561 cysN Leptospira interrogans serovar Lai str. 56601 sulfate adenylyltransferase subunit 1 NP_714399.1 4197000 R 189518 CDS NP_714400.1 24216919 1153562 complement(4198250..4199167) 1 NC_004342.2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 4199167 cysD 1153562 cysD Leptospira interrogans serovar Lai str. 56601 sulfate adenylyltransferase subunit 2 NP_714400.1 4198250 R 189518 CDS NP_714401.1 24216920 1153563 complement(4199164..4199904) 1 NC_004342.2 phosphoadenosine phosphosulfate reductase 4199904 cysH 1153563 cysH Leptospira interrogans serovar Lai str. 56601 phosphoadenosine phosphosulfate reductase NP_714401.1 4199164 R 189518 CDS NP_714404.2 294828494 1153566 4201574..4202890 1 NC_004342.2 oxidoreductase 4202890 1153566 LA_4224 Leptospira interrogans serovar Lai str. 56601 oxidoreductase NP_714404.2 4201574 D 189518 CDS NP_714406.1 24216925 1153568 4204270..4205181 1 NC_004342.2 hypothetical protein 4205181 1153568 LA_4226 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714406.1 4204270 D 189518 CDS YP_003573359.1 294828495 9006981 4205666..4205884 1 NC_004342.2 hypothetical protein 4205884 9006981 LA_4226a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573359.1 4205666 D 189518 CDS NP_714407.1 24216926 1153569 4206146..4207267 1 NC_004342.2 hydrolase 4207267 1153569 LA_4227 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_714407.1 4206146 D 189518 CDS NP_714408.1 24216927 1153570 4207369..4208379 1 NC_004342.2 ABC transporter permease 4208379 1153570 LA_4228 Leptospira interrogans serovar Lai str. 56601 ABC transporter permease NP_714408.1 4207369 D 189518 CDS NP_714409.2 294828496 1153571 4208376..4209419 1 NC_004342.2 dipeptide ABC transporter permease 4209419 1153571 LA_4229 Leptospira interrogans serovar Lai str. 56601 dipeptide ABC transporter permease NP_714409.2 4208376 D 189518 CDS NP_714410.1 24216929 1153572 4209416..4210417 1 NC_004342.2 ABC transporter ATP-binding protein 4210417 dppD 1153572 dppD Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_714410.1 4209416 D 189518 CDS NP_714411.1 24216930 1153573 4210414..4211367 1 NC_004342.2 ABC transporter ATP-binding protein 4211367 dppD 1153573 dppD Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_714411.1 4210414 D 189518 CDS NP_714412.1 24216931 1153574 4211346..4213427 1 NC_004342.2 hypothetical protein 4213427 1153574 LA_4232 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714412.1 4211346 D 189518 CDS NP_714413.1 24216932 1153575 4213451..4213873 1 NC_004342.2 hypothetical protein 4213873 1153575 LA_4233 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714413.1 4213451 D 189518 CDS NP_714415.1 24216934 1153577 4214254..4214784 1 NC_004342.2 hypothetical protein 4214784 1153577 LA_4235 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714415.1 4214254 D 189518 CDS NP_714416.1 24216935 1153578 complement(4214873..4216705) 1 NC_004342.2 DNA mismatch repair protein ATPase component 4216705 1153578 LA_4236 Leptospira interrogans serovar Lai str. 56601 DNA mismatch repair protein ATPase component NP_714416.1 4214873 R 189518 CDS NP_714417.1 24216936 1153579 complement(4216702..4216938) 1 NC_004342.2 hypothetical protein 4216938 1153579 LA_4237 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714417.1 4216702 R 189518 CDS YP_003573360.1 294828497 9006982 4217117..4217323 1 NC_004342.2 hypothetical protein 4217323 9006982 LA_4237a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573360.1 4217117 D 189518 CDS NP_714419.1 24216938 1153581 complement(4217532..4219154) 1 NC_004342.2 polysaccharide deacetylase 4219154 1153581 LA_4240 Leptospira interrogans serovar Lai str. 56601 polysaccharide deacetylase NP_714419.1 4217532 R 189518 CDS NP_714422.2 294828498 1153584 complement(4219737..4220738) 1 NC_004342.2 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4220738 ilvC 1153584 ilvC Leptospira interrogans serovar Lai str. 56601 ketol-acid reductoisomerase NP_714422.2 4219737 R 189518 CDS NP_714423.1 24216942 1153585 complement(4221751..4223343) 1 NC_004342.2 methyl-accepting chemotaxis protein 4223343 1153585 LA_4243 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_714423.1 4221751 R 189518 CDS NP_714424.2 294828499 1153586 4224043..4224492 1 NC_004342.2 redox protein OsmC 4224492 osmC 1153586 osmC Leptospira interrogans serovar Lai str. 56601 redox protein OsmC NP_714424.2 4224043 D 189518 CDS NP_714425.1 24216944 1153587 4224860..4226293 1 NC_004342.2 flavin-binding monooxygenase-like protein 4226293 1153587 LA_4245 Leptospira interrogans serovar Lai str. 56601 flavin-binding monooxygenase-like protein NP_714425.1 4224860 D 189518 CDS NP_714426.1 24216945 1153588 4226401..4227732 1 NC_004342.2 alkaline phosphatase 4227732 1153588 LA_4246 Leptospira interrogans serovar Lai str. 56601 alkaline phosphatase NP_714426.1 4226401 D 189518 CDS NP_714427.2 294828500 1153589 4227751..4228560 1 NC_004342.2 hydrolase 4228560 1153589 LA_4247 Leptospira interrogans serovar Lai str. 56601 hydrolase NP_714427.2 4227751 D 189518 CDS NP_714428.1 24216947 1153590 complement(4229212..4230075) 1 NC_004342.2 purine nucleoside phosphorylase 4230075 1153590 LA_4248 Leptospira interrogans serovar Lai str. 56601 purine nucleoside phosphorylase NP_714428.1 4229212 R 189518 CDS NP_714429.1 24216948 1153591 complement(4230716..4232284) 1 NC_004342.2 methyl-accepting chemotaxis protein 4232284 1153591 LA_4249 Leptospira interrogans serovar Lai str. 56601 methyl-accepting chemotaxis protein NP_714429.1 4230716 R 189518 CDS NP_714431.1 24216950 1153593 complement(4232860..4233690) 1 NC_004342.2 methylated-DNA--[protein]-cysteine S- methyltransferase 4233690 ada 1153593 ada Leptospira interrogans serovar Lai str. 56601 methylated-DNA--[protein]-cysteine S- methyltransferase NP_714431.1 4232860 R 189518 CDS NP_714432.1 24216951 1153594 4234203..4234913 1 NC_004342.2 hypothetical protein 4234913 1153594 LA_4252 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714432.1 4234203 D 189518 CDS NP_714433.1 24216952 1153595 complement(4235472..4236245) 1 NC_004342.2 ABC transporter substrate-binding protein 4236245 fepB 1153595 fepB Leptospira interrogans serovar Lai str. 56601 ABC transporter substrate-binding protein NP_714433.1 4235472 R 189518 CDS NP_714434.1 24216953 1153596 complement(4236267..4238252) 1 NC_004342.2 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4238252 acs 1153596 acs Leptospira interrogans serovar Lai str. 56601 acetyl-CoA synthetase NP_714434.1 4236267 R 189518 CDS NP_714435.1 24216954 1153597 complement(4238331..4238882) 1 NC_004342.2 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 4238882 folE 1153597 folE Leptospira interrogans serovar Lai str. 56601 GTP cyclohydrolase I NP_714435.1 4238331 R 189518 CDS NP_714437.1 24216956 1153599 4239276..4240487 1 NC_004342.2 mannosyltransferase 4240487 1153599 LA_4256 Leptospira interrogans serovar Lai str. 56601 mannosyltransferase NP_714437.1 4239276 D 189518 CDS NP_714438.1 24216957 1153600 complement(4241001..4241489) 1 NC_004342.2 hypothetical protein 4241489 1153600 LA_4258 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714438.1 4241001 R 189518 CDS NP_714439.2 294828501 1153601 complement(4241470..4241583) 1 NC_004342.2 transcriptional regulator 4241583 1153601 LA_4259 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_714439.2 4241470 R 189518 CDS NP_714441.1 24216960 1153603 complement(4243097..4244056) 1 NC_004342.2 dTDP-4-dehydrorhamnose 3,5-epimerase 4244056 1153603 LA_4261 Leptospira interrogans serovar Lai str. 56601 dTDP-4-dehydrorhamnose 3,5-epimerase NP_714441.1 4243097 R 189518 CDS NP_714442.1 24216961 1153604 4244152..4244556 1 NC_004342.2 hypothetical protein 4244556 1153604 LA_4262 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714442.1 4244152 D 189518 CDS NP_714443.1 24216962 1153605 complement(4244935..4245723) 1 NC_004342.2 hypothetical protein 4245723 1153605 LA_4263 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714443.1 4244935 R 189518 CDS NP_714444.1 24216963 1153606 4245829..4248258 1 NC_004342.2 glycerol-3-phosphate dehydrogenase 4248258 gpsA 1153606 gpsA Leptospira interrogans serovar Lai str. 56601 glycerol-3-phosphate dehydrogenase NP_714444.1 4245829 D 189518 CDS NP_714446.1 24216965 1153608 complement(4249297..4250460) 1 NC_004342.2 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 4250460 purT 1153608 purT Leptospira interrogans serovar Lai str. 56601 phosphoribosylglycinamide formyltransferase 2 NP_714446.1 4249297 R 189518 CDS NP_714447.1 24216966 1153609 complement(4250617..4251774) 1 NC_004342.2 hypothetical protein 4251774 1153609 LA_4267 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714447.1 4250617 R 189518 CDS NP_714448.1 24216967 1153610 complement(4252000..4253631) 1 NC_004342.2 transcriptional regulator 4253631 1153610 LA_4269 Leptospira interrogans serovar Lai str. 56601 transcriptional regulator NP_714448.1 4252000 R 189518 CDS NP_714450.2 294828502 1153612 4254128..4255096 1 NC_004342.2 permease-like protein 4255096 1153612 LA_4270 Leptospira interrogans serovar Lai str. 56601 permease-like protein NP_714450.2 4254128 D 189518 CDS NP_714452.1 24216971 1153614 4255451..4257403 1 NC_004342.2 hypothetical protein 4257403 1153614 LA_4272 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714452.1 4255451 D 189518 CDS NP_714453.1 24216972 1153615 4257422..4259143 1 NC_004342.2 formate hydrogenase subunit B 4259143 1153615 LA_4273 Leptospira interrogans serovar Lai str. 56601 formate hydrogenase subunit B NP_714453.1 4257422 D 189518 CDS NP_714454.1 24216973 1153616 4259110..4259997 1 NC_004342.2 formate hydrogenase subunit C 4259997 1153616 LA_4274 Leptospira interrogans serovar Lai str. 56601 formate hydrogenase subunit C NP_714454.1 4259110 D 189518 CDS NP_714455.1 24216974 1153617 4260016..4260636 1 NC_004342.2 formate hydrogenase subunit E 4260636 1153617 LA_4275 Leptospira interrogans serovar Lai str. 56601 formate hydrogenase subunit E NP_714455.1 4260016 D 189518 CDS NP_714456.1 24216975 1153618 4260633..4261841 1 NC_004342.2 formate hydrogenase subunit F 4261841 1153618 LA_4276 Leptospira interrogans serovar Lai str. 56601 formate hydrogenase subunit F NP_714456.1 4260633 D 189518 CDS NP_714457.1 24216976 1153619 4261842..4263242 1 NC_004342.2 metal (Ni/Fe) hydrogenase large subunit 4263242 hycE 1153619 hycE Leptospira interrogans serovar Lai str. 56601 metal (Ni/Fe) hydrogenase large subunit NP_714457.1 4261842 D 189518 CDS NP_714458.1 24216977 1153620 4263239..4264060 1 NC_004342.2 metal (Ni/Fe) hydrogenase small subunit 4264060 1153620 LA_4278 Leptospira interrogans serovar Lai str. 56601 metal (Ni/Fe) hydrogenase small subunit NP_714458.1 4263239 D 189518 CDS NP_714459.2 294828503 1153621 4264241..4265026 1 NC_004342.2 hypothetical protein 4265026 1153621 LA_4279 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714459.2 4264241 D 189518 CDS NP_714460.1 24216979 1153622 4265023..4265568 1 NC_004342.2 hypothetical protein 4265568 1153622 LA_4280 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714460.1 4265023 D 189518 CDS NP_714462.1 24216981 1153624 complement(4266052..4267467) 1 NC_004342.2 hypothetical protein 4267467 1153624 LA_4282 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714462.1 4266052 R 189518 CDS NP_714465.1 24216984 1153627 complement(4268641..4269570) 1 NC_004342.2 glycosyl hydrolase 4269570 1153627 LA_4285 Leptospira interrogans serovar Lai str. 56601 glycosyl hydrolase NP_714465.1 4268641 R 189518 CDS NP_714466.1 24216985 1153628 4269684..4270574 1 NC_004342.2 hypothetical protein 4270574 1153628 LA_4286 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714466.1 4269684 D 189518 CDS NP_714467.1 24216986 1153629 4270887..4271267 1 NC_004342.2 ABC transporter ATP-binding protein 4271267 1153629 LA_4287 Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_714467.1 4270887 D 189518 CDS NP_714468.1 24216987 1153630 4271268..4271834 1 NC_004342.2 ABC transporter ATP-binding protein 4271834 ccmA 1153630 ccmA Leptospira interrogans serovar Lai str. 56601 ABC transporter ATP-binding protein NP_714468.1 4271268 D 189518 CDS NP_714469.1 24216988 1153631 4271831..4272913 1 NC_004342.2 multidrug ABC transporter permease 4272913 1153631 LA_4289 Leptospira interrogans serovar Lai str. 56601 multidrug ABC transporter permease NP_714469.1 4271831 D 189518 CDS NP_714470.2 294828504 1153632 4272940..4274058 1 NC_004342.2 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 4274058 pyrD 1153632 pyrD Leptospira interrogans serovar Lai str. 56601 dihydroorotate dehydrogenase 2 NP_714470.2 4272940 D 189518 CDS NP_714471.1 24216990 1153633 4274162..4275604 1 NC_004342.2 hypothetical protein 4275604 1153633 LA_4291 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714471.1 4274162 D 189518 CDS NP_714472.2 294828505 1153634 4275627..4276199 1 NC_004342.2 hypothetical protein 4276199 1153634 LA_4292 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714472.2 4275627 D 189518 CDS NP_714473.1 24216992 1153635 complement(4276678..4277352) 1 NC_004342.2 hypothetical protein 4277352 1153635 LA_4293 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714473.1 4276678 R 189518 CDS NP_714474.2 294828506 1153636 4277400..4277942 1 NC_004342.2 phosphohistidine phosphatase SixA 4277942 sixA 1153636 sixA Leptospira interrogans serovar Lai str. 56601 phosphohistidine phosphatase SixA NP_714474.2 4277400 D 189518 CDS NP_714475.1 24216994 1153637 4277942..4278493 1 NC_004342.2 hypoxanthine phosphoribosyltransferase 4278493 hpt 1153637 hpt Leptospira interrogans serovar Lai str. 56601 hypoxanthine phosphoribosyltransferase NP_714475.1 4277942 D 189518 CDS NP_714476.1 24216995 1153638 4278785..4280557 1 NC_004342.2 sodium/hydrogen antiporter 4280557 kefB 1153638 kefB Leptospira interrogans serovar Lai str. 56601 sodium/hydrogen antiporter NP_714476.1 4278785 D 189518 CDS NP_714477.1 24216996 1153639 4280563..4280748 1 NC_004342.2 Fe-S protein 4280748 1153639 LA_4297 Leptospira interrogans serovar Lai str. 56601 Fe-S protein NP_714477.1 4280563 D 189518 CDS NP_714478.1 24216997 1153640 complement(4281276..4281722) 1 NC_004342.2 MarR family transcriptional regulator 4281722 marR 1153640 marR Leptospira interrogans serovar Lai str. 56601 MarR family transcriptional regulator NP_714478.1 4281276 R 189518 CDS NP_714479.1 24216998 1153641 complement(4281746..4282243) 1 NC_004342.2 glutathione peroxidase 4282243 btuE 1153641 btuE Leptospira interrogans serovar Lai str. 56601 glutathione peroxidase NP_714479.1 4281746 R 189518 CDS NP_714480.1 24216999 1153642 4282895..4283659 1 NC_004342.2 Hsp31/PfpI family protein 4283659 1153642 LA_4300 Leptospira interrogans serovar Lai str. 56601 Hsp31/PfpI family protein NP_714480.1 4282895 D 189518 CDS NP_714481.1 24217000 1153643 4283670..4285466 1 NC_004342.2 sodium/hydrogen antiporter 4285466 kefB 1153643 kefB Leptospira interrogans serovar Lai str. 56601 sodium/hydrogen antiporter NP_714481.1 4283670 D 189518 CDS NP_714484.1 24217003 1153646 4286461..4286967 1 NC_004342.2 hypothetical protein 4286967 1153646 LA_4304 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714484.1 4286461 D 189518 CDS NP_714485.2 294828507 1153647 complement(4287258..4288070) 1 NC_004342.2 hypothetical protein 4288070 1153647 LA_4305 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714485.2 4287258 R 189518 CDS NP_714486.1 24217005 1153648 complement(4288300..4288554) 1 NC_004342.2 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 4288554 csrA 1153648 csrA Leptospira interrogans serovar Lai str. 56601 carbon storage regulator NP_714486.1 4288300 R 189518 CDS NP_714487.1 24217006 1153649 complement(4288554..4289006) 1 NC_004342.2 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 4289006 1153649 LA_4307 Leptospira interrogans serovar Lai str. 56601 flagellar assembly protein FliW NP_714487.1 4288554 R 189518 CDS NP_714488.2 294828508 1153650 complement(4289048..4290313) 1 NC_004342.2 With FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL 4290313 1153650 LA_4308 Leptospira interrogans serovar Lai str. 56601 flagellar hook-associated protein FlgL NP_714488.2 4289048 R 189518 CDS NP_714489.1 24217008 1153651 complement(4290354..4292264) 1 NC_004342.2 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 4292264 flgK 1153651 flgK Leptospira interrogans serovar Lai str. 56601 flagellar hook-associated protein FlgK NP_714489.1 4290354 R 189518 CDS NP_714490.1 24217009 1153652 complement(4292297..4292824) 1 NC_004342.2 hypothetical protein 4292824 1153652 LA_4310 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714490.1 4292297 R 189518 CDS NP_714491.2 294828509 1153653 4294012..4295088 1 NC_004342.2 cytoplasmic membrane protein 4295088 1153653 LA_4311 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_714491.2 4294012 D 189518 CDS NP_714492.1 24217011 1153654 complement(4295673..4295975) 1 NC_004342.2 hypothetical protein 4295975 1153654 LA_4312 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714492.1 4295673 R 189518 CDS NP_714494.1 24217013 1153656 complement(4296764..4297861) 1 NC_004342.2 hypothetical protein 4297861 1153656 LA_4315 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714494.1 4296764 R 189518 CDS NP_714495.2 294828510 1153657 4297860..4298456 1 NC_004342.2 hypothetical protein 4298456 1153657 LA_4314 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714495.2 4297860 D 189518 CDS YP_003573361.1 294828511 9006983 complement(4299029..4299358) 1 NC_004342.2 hypothetical protein 4299358 9006983 LA_4314a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003573361.1 4299029 R 189518 CDS NP_714498.2 294828512 1153660 4299702..4300070 1 NC_004342.2 hypothetical protein 4300070 1153660 LA_4318 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714498.2 4299702 D 189518 CDS NP_714499.1 24217018 1153661 4300079..4300666 1 NC_004342.2 hypothetical protein 4300666 1153661 LA_4319 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714499.1 4300079 D 189518 CDS NP_714500.1 24217019 1153662 4300685..4301071 1 NC_004342.2 hypothetical protein 4301071 1153662 LA_4320 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714500.1 4300685 D 189518 CDS NP_714501.1 24217020 1153663 complement(4301068..4301433) 1 NC_004342.2 hypothetical protein 4301433 1153663 LA_4321 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714501.1 4301068 R 189518 CDS NP_714502.2 294828513 1153664 complement(4301399..4302943) 1 NC_004342.2 carboxypeptidase I 4302943 1153664 LA_4322 Leptospira interrogans serovar Lai str. 56601 carboxypeptidase I NP_714502.2 4301399 R 189518 CDS NP_714504.1 24217023 1153666 4305139..4306557 1 NC_004342.2 hypothetical protein 4306557 1153666 LA_4324 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714504.1 4305139 D 189518 CDS NP_714505.1 24217024 1153667 complement(4306640..4306837) 1 NC_004342.2 hypothetical protein 4306837 1153667 LA_4325 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714505.1 4306640 R 189518 CDS NP_714506.1 24217025 1153668 complement(4306898..4308013) 1 NC_004342.2 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 4308013 lpxD 1153668 lpxD Leptospira interrogans serovar Lai str. 56601 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_714506.1 4306898 R 189518 CDS NP_714507.2 294828514 1153669 4308172..4309104 1 NC_004342.2 ferredoxin-NADP reductase 4309104 1153669 LA_4327 Leptospira interrogans serovar Lai str. 56601 ferredoxin-NADP reductase NP_714507.2 4308172 D 189518 CDS NP_714509.1 24217028 1153671 4309723..4309938 1 NC_004342.2 transcriptional coactivator-like protein 4309938 1153671 LA_4329 Leptospira interrogans serovar Lai str. 56601 transcriptional coactivator-like protein NP_714509.1 4309723 D 189518 CDS NP_714510.1 24217029 1153672 4310455..4311060 1 NC_004342.2 cytidine deaminase 4311060 cumB 1153672 cumB Leptospira interrogans serovar Lai str. 56601 cytidine deaminase NP_714510.1 4310455 D 189518 CDS NP_714511.2 294828515 1153673 4311190..4312629 1 NC_004342.2 DNA polymerase III subunit gamma 4312629 dnaX 1153673 dnaX Leptospira interrogans serovar Lai str. 56601 DNA polymerase III subunit gamma NP_714511.2 4311190 D 189518 CDS NP_714512.1 24217031 1153674 4312634..4312981 1 NC_004342.2 hypothetical protein 4312981 1153674 LA_4332 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714512.1 4312634 D 189518 CDS NP_714513.1 24217032 1153675 4312962..4313567 1 NC_004342.2 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 4313567 recR 1153675 recR Leptospira interrogans serovar Lai str. 56601 recombination protein RecR NP_714513.1 4312962 D 189518 CDS NP_714515.1 24217034 1153677 complement(4313957..4315531) 1 NC_004342.2 hypothetical protein 4315531 1153677 LA_4335 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714515.1 4313957 R 189518 CDS NP_714516.1 24217035 1153678 complement(4315535..4316383) 1 NC_004342.2 peptide ABC transporter periplasmic 4316383 1153678 LA_4336 Leptospira interrogans serovar Lai str. 56601 peptide ABC transporter periplasmic NP_714516.1 4315535 R 189518 CDS NP_714517.1 24217036 1153679 complement(4316447..4317733) 1 NC_004342.2 OmpA family protein 4317733 1153679 LA_4337 Leptospira interrogans serovar Lai str. 56601 OmpA family protein NP_714517.1 4316447 R 189518 CDS NP_714519.1 24217038 1153681 complement(4318836..4320089) 1 NC_004342.2 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 4320089 serS 1153681 serS Leptospira interrogans serovar Lai str. 56601 seryl-tRNA synthetase NP_714519.1 4318836 R 189518 CDS NP_714520.1 24217039 1153682 complement(4320082..4320891) 1 NC_004342.2 Mg-dependent DNase 4320891 tatD 1153682 tatD Leptospira interrogans serovar Lai str. 56601 Mg-dependent DNase NP_714520.1 4320082 R 189518 CDS NP_714521.1 24217040 1153683 4321012..4322031 1 NC_004342.2 metalloendopeptidase 4322031 1153683 LA_4341 Leptospira interrogans serovar Lai str. 56601 metalloendopeptidase NP_714521.1 4321012 D 189518 CDS NP_714522.1 24217041 1153684 4322031..4322378 1 NC_004342.2 cell shape determination protein 4322378 1153684 LA_4342 Leptospira interrogans serovar Lai str. 56601 cell shape determination protein NP_714522.1 4322031 D 189518 CDS NP_714523.1 24217042 1153685 4322375..4322872 1 NC_004342.2 hypothetical protein 4322872 1153685 LA_4343 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714523.1 4322375 D 189518 CDS NP_714525.1 24217044 1153687 complement(4323829..4324650) 1 NC_004342.2 cytoplasmic membrane protein 4324650 1153687 LA_4345 Leptospira interrogans serovar Lai str. 56601 cytoplasmic membrane protein NP_714525.1 4323829 R 189518 CDS NP_714526.1 24217045 1153688 complement(4324712..4325587) 1 NC_004342.2 ParB-like protein 4325587 parB 1153688 parB Leptospira interrogans serovar Lai str. 56601 ParB-like protein NP_714526.1 4324712 R 189518 CDS NP_714527.2 294828516 1153689 complement(4325590..4326351) 1 NC_004342.2 ParA 4326351 parA 1153689 parA Leptospira interrogans serovar Lai str. 56601 ParA NP_714527.2 4325590 R 189518 CDS NP_714528.1 24217047 1153690 complement(4326329..4327093) 1 NC_004342.2 glucose-inhibited division protein B 4327093 1153690 LA_4348 Leptospira interrogans serovar Lai str. 56601 glucose-inhibited division protein B NP_714528.1 4326329 R 189518 CDS NP_714529.1 24217048 1153691 complement(4328128..4329576) 1 NC_004342.2 metallopeptidase 4329576 1153691 LA_4349 Leptospira interrogans serovar Lai str. 56601 metallopeptidase NP_714529.1 4328128 R 189518 CDS NP_714533.2 294828517 1153695 complement(4331202..4331360) 1 NC_004342.2 transposase 4331360 1153695 LA_4353 Leptospira interrogans serovar Lai str. 56601 transposase NP_714533.2 4331202 R 189518 CDS NP_714535.1 24217054 1153697 4332296..4333126 1 NC_004342.2 hypothetical protein 4333126 1153697 LA_4355 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714535.1 4332296 D 189518 CDS NP_714539.1 24217058 1153701 complement(4334619..4336526) 1 NC_004342.2 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4336526 gidA 1153701 gidA Leptospira interrogans serovar Lai str. 56601 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NP_714539.1 4334619 R 189518 CDS NP_714540.2 294828518 1153702 4336670..4337593 1 NC_004342.2 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4337593 ilvE 1153702 ilvE Leptospira interrogans serovar Lai str. 56601 branched-chain amino acid aminotransferase NP_714540.2 4336670 D 189518 CDS NP_714541.1 24217060 1153703 4337600..4338532 1 NC_004342.2 DNA polymerase III gamma and tau subunits 4338532 1153703 LA_4361 Leptospira interrogans serovar Lai str. 56601 DNA polymerase III gamma and tau subunits NP_714541.1 4337600 D 189518 CDS NP_714545.1 24217062 1153927 15..2531 1 NC_004343.2 hypothetical protein 2531 1153927 LB_001 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714545.1 15 D 189518 CDS NP_714546.2 294653594 1153928 2542..3423 1 NC_004343.2 5,10-methylenetetrahydrofolate reductase 3423 metF 1153928 metF Leptospira interrogans serovar Lai str. 56601 5,10-methylenetetrahydrofolate reductase NP_714546.2 2542 D 189518 CDS NP_714549.1 24217066 1153931 complement(4066..4890) 1 NC_004343.2 hypothetical protein 4890 1153931 LB_005 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714549.1 4066 R 189518 CDS NP_714552.2 294653593 1153934 5251..6111 1 NC_004343.2 hypothetical protein 6111 1153934 LB_008 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714552.2 5251 D 189518 CDS NP_714554.1 24217071 1153936 6409..7278 1 NC_004343.2 glutamyl-tRNA reductase 7278 hemA 1153936 hemA Leptospira interrogans serovar Lai str. 56601 glutamyl-tRNA reductase NP_714554.1 6409 D 189518 CDS NP_714555.2 294653592 1153937 7263..8891 1 NC_004343.2 confirmed by proteomics; porphobilinogen deaminase 8891 hemC 1153937 hemC Leptospira interrogans serovar Lai str. 56601 porphobilinogen deaminase NP_714555.2 7263 D 189518 CDS NP_714556.1 24217073 1153938 8860..9813 1 NC_004343.2 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 9813 hemB 1153938 hemB Leptospira interrogans serovar Lai str. 56601 delta-aminolevulinic acid dehydratase NP_714556.1 8860 D 189518 CDS NP_714557.1 24217074 1153939 9810..11141 1 NC_004343.2 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 11141 hemL 1153939 hemL Leptospira interrogans serovar Lai str. 56601 glutamate-1-semialdehyde aminotransferase NP_714557.1 9810 D 189518 CDS NP_714558.1 24217075 1153940 11141..12058 1 NC_004343.2 two-component hybrid sensor and regulator 12058 1153940 LB_014 Leptospira interrogans serovar Lai str. 56601 two-component hybrid sensor and regulator NP_714558.1 11141 D 189518 CDS NP_714559.1 24217076 1153941 12055..12747 1 NC_004343.2 two-component response regulator 12747 1153941 LB_015 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_714559.1 12055 D 189518 CDS NP_714560.2 294653591 1153942 12737..13759 1 NC_004343.2 uroporphyrinogen decarboxylase 13759 hemE 1153942 hemE Leptospira interrogans serovar Lai str. 56601 uroporphyrinogen decarboxylase NP_714560.2 12737 D 189518 CDS NP_714561.1 24217078 1153943 13666..15105 1 NC_004343.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 15105 hemF 1153943 hemF Leptospira interrogans serovar Lai str. 56601 coproporphyrinogen III oxidase NP_714561.1 13666 D 189518 CDS NP_714562.1 24217079 1153944 15185..16168 1 NC_004343.2 hypothetical protein 16168 1153944 LB_018 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714562.1 15185 D 189518 CDS NP_714564.1 24217081 1153946 16380..17663 1 NC_004343.2 protoporphyrinogen oxidase 17663 hemG 1153946 hemG Leptospira interrogans serovar Lai str. 56601 protoporphyrinogen oxidase NP_714564.1 16380 D 189518 CDS NP_714566.2 294653590 1153948 18298..19467 1 NC_004343.2 transposase 19467 1153948 LB_022 Leptospira interrogans serovar Lai str. 56601 transposase NP_714566.2 18298 D 189518 CDS NP_714567.1 24217084 1153949 complement(19838..20134) 1 NC_004343.2 ferrochelatase 20134 1153949 LB_023 Leptospira interrogans serovar Lai str. 56601 ferrochelatase NP_714567.1 19838 R 189518 CDS NP_714568.1 24217085 1153950 complement(20175..20747) 1 NC_004343.2 ferrochelatase 20747 1153950 LB_024 Leptospira interrogans serovar Lai str. 56601 ferrochelatase NP_714568.1 20175 R 189518 CDS NP_714569.1 24217086 1153951 complement(21007..22149) 1 NC_004343.2 hypothetical protein 22149 1153951 LB_025 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714569.1 21007 R 189518 CDS NP_714570.1 24217087 1153952 22311..23228 1 NC_004343.2 ParA protein 23228 parA3 1153952 parA3 Leptospira interrogans serovar Lai str. 56601 ParA protein NP_714570.1 22311 D 189518 CDS NP_714571.1 24217088 1153953 23221..23928 1 NC_004343.2 ParB protein 23928 parB3 1153953 parB3 Leptospira interrogans serovar Lai str. 56601 ParB protein NP_714571.1 23221 D 189518 CDS NP_714572.1 24217089 1153954 24028..24630 1 NC_004343.2 reductase 24630 1153954 LB_028 Leptospira interrogans serovar Lai str. 56601 reductase NP_714572.1 24028 D 189518 CDS NP_714574.1 24217091 1153956 complement(25232..26395) 1 NC_004343.2 intercellular adhesion protein C 26395 1153956 LB_030 Leptospira interrogans serovar Lai str. 56601 intercellular adhesion protein C NP_714574.1 25232 R 189518 CDS NP_714576.2 294653589 1153958 26500..26850 1 NC_004343.2 cyclic nucleotide dependent protein kinase 26850 1153958 LB_031 Leptospira interrogans serovar Lai str. 56601 cyclic nucleotide dependent protein kinase NP_714576.2 26500 D 189518 CDS NP_714578.1 24217095 1153960 27246..28001 1 NC_004343.2 3-oxoacyl-ACP reductase 28001 1153960 LB_034 Leptospira interrogans serovar Lai str. 56601 3-oxoacyl-ACP reductase NP_714578.1 27246 D 189518 CDS NP_714579.1 24217096 1153961 27977..28528 1 NC_004343.2 low molecular weight phosphotyrosine protein phosphatase 28528 amsI 1153961 amsI Leptospira interrogans serovar Lai str. 56601 low molecular weight phosphotyrosine protein phosphatase NP_714579.1 27977 D 189518 CDS NP_714580.1 24217097 1153962 28558..29826 1 NC_004343.2 NADH dehydrogenase 29826 ndh 1153962 ndh Leptospira interrogans serovar Lai str. 56601 NADH dehydrogenase NP_714580.1 28558 D 189518 CDS NP_714581.2 294653588 1153963 29829..30281 1 NC_004343.2 sucrose/H+ symporter 30281 1153963 LB_037 Leptospira interrogans serovar Lai str. 56601 sucrose/H+ symporter NP_714581.2 29829 D 189518 CDS NP_714583.1 24217100 1153965 complement(30706..31314) 1 NC_004343.2 hypothetical protein 31314 1153965 LB_039 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714583.1 30706 R 189518 CDS NP_714584.2 294653587 1153966 complement(31360..31728) 1 NC_004343.2 hypothetical protein 31728 1153966 LB_040 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714584.2 31360 R 189518 CDS NP_714585.2 294653586 1153967 31703..32506 1 NC_004343.2 3-oxoacyl-ACP reductase 32506 1153967 LB_041 Leptospira interrogans serovar Lai str. 56601 3-oxoacyl-ACP reductase NP_714585.2 31703 D 189518 CDS NP_714586.1 24217103 1153968 32516..32938 1 NC_004343.2 hypothetical protein 32938 1153968 LB_042 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714586.1 32516 D 189518 CDS NP_714587.1 24217104 1153969 33000..33371 1 NC_004343.2 confirmed by proteomics; hypothetical protein 33371 1153969 LB_043 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714587.1 33000 D 189518 CDS NP_714588.1 24217105 1153970 33697..34767 1 NC_004343.2 hypothetical protein 34767 1153970 LB_044 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714588.1 33697 D 189518 CDS NP_714589.2 294653585 1153971 complement(35199..35381) 1 NC_004343.2 hypothetical protein 35381 1153971 LB_045 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714589.2 35199 R 189518 CDS NP_714591.2 294653584 1153973 36007..37326 1 NC_004343.2 hypothetical protein 37326 1153973 LB_047 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714591.2 36007 D 189518 CDS NP_714592.2 294653583 1153974 37820..38989 1 NC_004343.2 transposase 38989 1153974 LB_048 Leptospira interrogans serovar Lai str. 56601 transposase NP_714592.2 37820 D 189518 CDS NP_714594.1 24217111 1153976 40098..40712 1 NC_004343.2 hypothetical protein 40712 1153976 LB_050 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714594.1 40098 D 189518 CDS NP_714595.2 294653582 1153977 40863..41846 1 NC_004343.2 magnesium chelatase, putative 41846 1153977 LB_051 Leptospira interrogans serovar Lai str. 56601 magnesium chelatase, putative NP_714595.2 40863 D 189518 CDS NP_714596.1 24217113 1153978 41853..42683 1 NC_004343.2 hypothetical protein 42683 1153978 LB_052 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714596.1 41853 D 189518 CDS NP_714597.1 24217114 1153979 42680..43549 1 NC_004343.2 hypothetical protein 43549 1153979 LB_053 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714597.1 42680 D 189518 CDS NP_714598.2 294653581 1153980 43546..44484 1 NC_004343.2 von Willebrand factor type A domain-containing protein 44484 vwa1 1153980 vwa1 Leptospira interrogans serovar Lai str. 56601 von Willebrand factor type A domain-containing protein NP_714598.2 43546 D 189518 CDS NP_714599.2 294653580 1153981 44568..45524 1 NC_004343.2 von Willebrand factor type A domain-containing protein 45524 vwa2 1153981 vwa2 Leptospira interrogans serovar Lai str. 56601 von Willebrand factor type A domain-containing protein NP_714599.2 44568 D 189518 CDS NP_714600.2 294653579 1153982 45521..46210 1 NC_004343.2 hypothetical protein 46210 1153982 LB_056 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714600.2 45521 D 189518 CDS NP_714601.1 24217118 1153983 46207..47850 1 NC_004343.2 BatD protein 47850 batD 1153983 batD Leptospira interrogans serovar Lai str. 56601 BatD protein NP_714601.1 46207 D 189518 CDS NP_714602.1 24217119 1153984 47847..49670 1 NC_004343.2 molecular chaperone; heat shock protein 90 49670 htpG2 1153984 htpG2 Leptospira interrogans serovar Lai str. 56601 heat shock protein 90 NP_714602.1 47847 D 189518 CDS NP_714603.1 24217120 1153985 49688..50257 1 NC_004343.2 hypothetical protein 50257 1153985 LB_059 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714603.1 49688 D 189518 CDS NP_714604.1 24217121 1153986 complement(50238..50729) 1 NC_004343.2 hypothetical protein 50729 1153986 LB_060 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714604.1 50238 R 189518 CDS NP_714605.1 24217122 1153987 50959..52557 1 NC_004343.2 hypothetical protein 52557 1153987 LB_061 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714605.1 50959 D 189518 CDS NP_714606.1 24217123 1153988 complement(52565..52909) 1 NC_004343.2 anti-anti-sigma factor 52909 1153988 LB_062 Leptospira interrogans serovar Lai str. 56601 anti-anti-sigma factor NP_714606.1 52565 R 189518 CDS NP_714607.2 294653578 1153989 complement(52906..53898) 1 NC_004343.2 hypothetical protein 53898 1153989 LB_063 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714607.2 52906 R 189518 CDS NP_714609.2 294653577 1153991 53998..54918 1 NC_004343.2 hypothetical protein 54918 1153991 LB_065 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714609.2 53998 D 189518 CDS NP_714610.1 24217127 1153992 54915..55394 1 NC_004343.2 hypothetical protein 55394 1153992 LB_066 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714610.1 54915 D 189518 CDS NP_714612.1 24217129 1153994 55772..56593 1 NC_004343.2 stearoyl-CoA desaturase; fatty acid desaturase 56593 1153994 LB_068 Leptospira interrogans serovar Lai str. 56601 fatty acid desaturase NP_714612.1 55772 D 189518 CDS NP_714613.1 24217130 1153995 57309..57893 1 NC_004343.2 hypothetical protein 57893 1153995 LB_069 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714613.1 57309 D 189518 CDS NP_714614.1 24217131 1153996 59172..59822 1 NC_004343.2 hypothetical protein 59822 1153996 LB_070 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714614.1 59172 D 189518 CDS NP_714615.2 294653576 1153997 60402..60638 1 NC_004343.2 hypothetical protein 60638 1153997 LB_071 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714615.2 60402 D 189518 CDS NP_714616.2 294653575 1153998 61315..61851 1 NC_004343.2 hypothetical protein 61851 1153998 LB_072 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714616.2 61315 D 189518 CDS NP_714617.2 294653574 1153999 complement(61981..62931) 1 NC_004343.2 ArgK family; lysine arginine ornithine transport system kinase 62931 1153999 LB_073 Leptospira interrogans serovar Lai str. 56601 lysine arginine ornithine transport system kinase NP_714617.2 61981 R 189518 CDS NP_714618.1 24217135 1154000 complement(62957..64969) 1 NC_004343.2 methylmalonyl-CoA mutase 64969 mcm2 1154000 mcm2 Leptospira interrogans serovar Lai str. 56601 methylmalonyl-CoA mutase NP_714618.1 62957 R 189518 CDS NP_714620.1 24217137 1154002 65076..66413 1 NC_004343.2 hypothetical protein 66413 1154002 LB_075 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714620.1 65076 D 189518 CDS NP_714621.1 24217138 1154003 67553..68245 1 NC_004343.2 hypothetical protein 68245 1154003 LB_077 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714621.1 67553 D 189518 CDS NP_714622.1 24217139 1154004 complement(68865..69938) 1 NC_004343.2 hypothetical protein 69938 1154004 LB_078 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714622.1 68865 R 189518 CDS NP_714623.1 24217140 1154005 70067..70345 1 NC_004343.2 phosphoribosyl-ATP pyrophosphohydrolase 70345 hisE 1154005 hisE Leptospira interrogans serovar Lai str. 56601 phosphoribosyl-ATP pyrophosphohydrolase NP_714623.1 70067 D 189518 CDS NP_714624.2 294653573 1154006 70454..72280 1 NC_004343.2 hypothetical protein 72280 1154006 LB_080 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714624.2 70454 D 189518 CDS NP_714626.1 24217143 1154008 72749..73513 1 NC_004343.2 3-ketoacyl-ACP reductase 73513 1154008 LB_082 Leptospira interrogans serovar Lai str. 56601 3-ketoacyl-ACP reductase NP_714626.1 72749 D 189518 CDS NP_714627.1 24217144 1154009 74006..74239 1 NC_004343.2 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 74239 acpP 1154009 acpP Leptospira interrogans serovar Lai str. 56601 acyl carrier protein NP_714627.1 74006 D 189518 CDS NP_714628.1 24217145 1154010 74293..75036 1 NC_004343.2 ribonuclease III 75036 1154010 LB_084 Leptospira interrogans serovar Lai str. 56601 ribonuclease III NP_714628.1 74293 D 189518 CDS NP_714629.1 24217146 1154011 75411..75998 1 NC_004343.2 MutT/nudix family protein 75998 1154011 LB_085 Leptospira interrogans serovar Lai str. 56601 MutT/nudix family protein NP_714629.1 75411 D 189518 CDS NP_714630.1 24217147 1154012 75995..77080 1 NC_004343.2 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 77080 aroB 1154012 aroB Leptospira interrogans serovar Lai str. 56601 3-dehydroquinate synthase NP_714630.1 75995 D 189518 CDS NP_714631.1 24217148 1154013 77080..77961 1 NC_004343.2 hypothetical protein 77961 1154013 LB_087 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714631.1 77080 D 189518 CDS NP_714632.1 24217149 1154014 78288..78662 1 NC_004343.2 hypothetical protein 78662 1154014 LB_088 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714632.1 78288 D 189518 CDS NP_714633.1 24217150 1154015 79179..80735 1 NC_004343.2 confirmed by proteomics; hypothetical protein 80735 1154015 LB_089 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714633.1 79179 D 189518 CDS NP_714634.1 24217151 1154016 80785..81324 1 NC_004343.2 hypothetical protein 81324 1154016 LB_090 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714634.1 80785 D 189518 CDS NP_714635.1 24217152 1154017 complement(81632..81871) 1 NC_004343.2 hypothetical protein 81871 1154017 LB_091 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714635.1 81632 R 189518 CDS NP_714636.1 24217153 1154018 complement(81925..82335) 1 NC_004343.2 hypothetical protein 82335 1154018 LB_092 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714636.1 81925 R 189518 CDS NP_714637.1 24217154 1154019 complement(82392..84329) 1 NC_004343.2 long-chain-fatty-acid--CoA ligase 84329 fadD 1154019 fadD Leptospira interrogans serovar Lai str. 56601 long-chain-fatty-acid--CoA ligase NP_714637.1 82392 R 189518 CDS NP_714638.1 24217155 1154020 84491..87430 1 NC_004343.2 confirmed by proteomics; adenylate cyclase 87430 cyaA17 1154020 cyaA17 Leptospira interrogans serovar Lai str. 56601 adenylate cyclase NP_714638.1 84491 D 189518 CDS NP_714640.1 24217157 1154022 complement(87988..88740) 1 NC_004343.2 hypothetical protein 88740 1154022 LB_096 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714640.1 87988 R 189518 CDS NP_714641.2 294653572 1154023 complement(88780..90093) 1 NC_004343.2 xylanase/chitin deacetilase 90093 1154023 LB_098 Leptospira interrogans serovar Lai str. 56601 xylanase/chitin deacetilase NP_714641.2 88780 R 189518 CDS NP_714643.1 24217160 1154025 complement(90403..90918) 1 NC_004343.2 hypothetical protein 90918 1154025 LB_099 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714643.1 90403 R 189518 CDS NP_714646.1 24217163 1154028 91672..92481 1 NC_004343.2 phospholysine phosphohistidine inorganic pyrophosphate phosphatase 92481 1154028 LB_102 Leptospira interrogans serovar Lai str. 56601 phospholysine phosphohistidine inorganic pyrophosphate phosphatase NP_714646.1 91672 D 189518 CDS NP_714647.1 24217164 1154029 complement(92488..92916) 1 NC_004343.2 hypothetical protein 92916 1154029 LB_103 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714647.1 92488 R 189518 CDS NP_714648.1 24217165 1154030 complement(93181..93759) 1 NC_004343.2 TetR family transcriptional regulator 93759 1154030 LB_104 Leptospira interrogans serovar Lai str. 56601 TetR family transcriptional regulator NP_714648.1 93181 R 189518 CDS NP_714649.2 294653571 1154031 94627..95610 1 NC_004343.2 arsR family transcriptional regulator 95610 1154031 LB_105 Leptospira interrogans serovar Lai str. 56601 arsR family transcriptional regulator NP_714649.2 94627 D 189518 CDS NP_714650.1 24217167 1154032 95612..96922 1 NC_004343.2 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 96922 1154032 LB_106 Leptospira interrogans serovar Lai str. 56601 S-adenosyl-L-homocysteine hydrolase NP_714650.1 95612 D 189518 CDS NP_714651.1 24217168 1154033 96995..97294 1 NC_004343.2 ferredoxin 97294 1154033 LB_107 Leptospira interrogans serovar Lai str. 56601 ferredoxin NP_714651.1 96995 D 189518 CDS NP_714652.1 24217169 1154034 97341..101084 1 NC_004343.2 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 101084 metH 1154034 metH Leptospira interrogans serovar Lai str. 56601 B12-dependent methionine synthase NP_714652.1 97341 D 189518 CDS NP_714653.1 24217170 1154035 101193..101531 1 NC_004343.2 hypothetical protein 101531 1154035 LB_109 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714653.1 101193 D 189518 CDS NP_714654.1 24217171 1154036 complement(101979..102911) 1 NC_004343.2 outermembrane protein 102911 1154036 LB_110 Leptospira interrogans serovar Lai str. 56601 outermembrane protein NP_714654.1 101979 R 189518 CDS NP_714655.1 24217172 1154037 103023..104318 1 NC_004343.2 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate; diphosphate--fructose-6-phosphate 1-phosphotransferase 104318 1154037 LB_111 Leptospira interrogans serovar Lai str. 56601 diphosphate--fructose-6-phosphate 1-phosphotransferase NP_714655.1 103023 D 189518 CDS NP_714656.1 24217173 1154038 complement(104517..106262) 1 NC_004343.2 regulatory protein 106262 1154038 LB_112 Leptospira interrogans serovar Lai str. 56601 regulatory protein NP_714656.1 104517 R 189518 CDS NP_714657.1 24217174 1154039 complement(106440..107324) 1 NC_004343.2 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 107324 argB 1154039 argB Leptospira interrogans serovar Lai str. 56601 acetylglutamate kinase NP_714657.1 106440 R 189518 CDS NP_714658.2 294653570 1154040 107314..108132 1 NC_004343.2 confirmed by proteomics; 3-oxoacyl-ACP reductase 108132 1154040 LB_113 Leptospira interrogans serovar Lai str. 56601 3-oxoacyl-ACP reductase NP_714658.2 107314 D 189518 CDS NP_714660.1 24217177 1154042 complement(109072..110814) 1 NC_004343.2 hypothetical protein 110814 1154042 LB_116 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714660.1 109072 R 189518 CDS NP_714661.2 294653569 1154043 complement(110807..111283) 1 NC_004343.2 confirmed by proteomics; bacterioferritin comigratory protein 111283 1154043 LB_117 Leptospira interrogans serovar Lai str. 56601 bacterioferritin comigratory protein NP_714661.2 110807 R 189518 CDS NP_714662.1 24217179 1154044 111451..113616 1 NC_004343.2 adenylate cyclase 113616 cyaA18 1154044 cyaA18 Leptospira interrogans serovar Lai str. 56601 adenylate cyclase NP_714662.1 111451 D 189518 CDS NP_714663.2 294653568 1154045 114780..115148 1 NC_004343.2 hypothetical protein 115148 1154045 LB_119 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714663.2 114780 D 189518 CDS NP_714664.1 24217181 1154046 115195..116292 1 NC_004343.2 hypothetical protein 116292 1154046 LB_120 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714664.1 115195 D 189518 CDS NP_714665.1 24217182 1154047 116309..117121 1 NC_004343.2 3-oxoacyl-ACP reductase 117121 1154047 LB_121 Leptospira interrogans serovar Lai str. 56601 3-oxoacyl-ACP reductase NP_714665.1 116309 D 189518 CDS NP_714666.1 24217183 1154048 complement(117170..118069) 1 NC_004343.2 site-specific integrase/recombinase XerD-like protein 118069 1154048 LB_122 Leptospira interrogans serovar Lai str. 56601 site-specific integrase/recombinase XerD-like protein NP_714666.1 117170 R 189518 CDS NP_714667.1 24217184 1154049 complement(118185..118724) 1 NC_004343.2 confirmed by proteomics; shikimic acid kinase I 118724 aroK 1154049 aroK Leptospira interrogans serovar Lai str. 56601 shikimic acid kinase I NP_714667.1 118185 R 189518 CDS NP_714668.1 24217185 1154050 complement(118721..119572) 1 NC_004343.2 HD-GYP domain-containing protein 119572 1154050 LB_124 Leptospira interrogans serovar Lai str. 56601 HD-GYP domain-containing protein NP_714668.1 118721 R 189518 CDS NP_714669.2 294653567 1154051 complement(119578..120084) 1 NC_004343.2 chemotaxis protein 120084 cheD2 1154051 cheD2 Leptospira interrogans serovar Lai str. 56601 chemotaxis protein NP_714669.2 119578 R 189518 CDS NP_714670.1 24217187 1154052 120256..121482 1 NC_004343.2 pheromone shutdown protein 121482 traB 1154052 traB Leptospira interrogans serovar Lai str. 56601 pheromone shutdown protein NP_714670.1 120256 D 189518 CDS NP_714671.1 24217188 1154053 121806..122369 1 NC_004343.2 hypothetical protein 122369 1154053 LB_127 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714671.1 121806 D 189518 CDS NP_714674.1 24217191 1154056 complement(123147..124292) 1 NC_004343.2 araC family transcriptional regulator 124292 1154056 LB_130 Leptospira interrogans serovar Lai str. 56601 araC family transcriptional regulator NP_714674.1 123147 R 189518 CDS NP_714675.1 24217192 1154057 complement(124577..125686) 1 NC_004343.2 araC family transcriptional regulator 125686 1154057 LB_131 Leptospira interrogans serovar Lai str. 56601 araC family transcriptional regulator NP_714675.1 124577 R 189518 CDS NP_714677.2 294653566 1154059 127052..128533 1 NC_004343.2 EAL domain-containing protein 128533 1154059 LB_133 Leptospira interrogans serovar Lai str. 56601 EAL domain-containing protein NP_714677.2 127052 D 189518 CDS NP_714678.2 294653565 1154060 129449..129829 1 NC_004343.2 hypothetical protein 129829 1154060 LB_134 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714678.2 129449 D 189518 CDS NP_714680.1 24217197 1154062 complement(130769..131167) 1 NC_004343.2 anti-sigma factor antagonist 131167 1154062 LB_136 Leptospira interrogans serovar Lai str. 56601 anti-sigma factor antagonist NP_714680.1 130769 R 189518 CDS NP_714681.1 24217198 1154063 complement(131178..132176) 1 NC_004343.2 hypothetical protein 132176 1154063 LB_137 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714681.1 131178 R 189518 CDS NP_714682.1 24217199 1154064 complement(132173..133630) 1 NC_004343.2 hypothetical protein 133630 1154064 LB_138 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714682.1 132173 R 189518 CDS NP_714683.2 294653564 1154065 complement(133633..135120) 1 NC_004343.2 serine phosphatase RsbU 135120 1154065 LB_139 Leptospira interrogans serovar Lai str. 56601 serine phosphatase RsbU NP_714683.2 133633 R 189518 CDS NP_714685.1 24217202 1154067 complement(136740..137447) 1 NC_004343.2 lipoprotein qlp42 137447 1154067 LB_141 Leptospira interrogans serovar Lai str. 56601 lipoprotein qlp42 NP_714685.1 136740 R 189518 CDS NP_714686.1 24217203 1154068 complement(137700..138251) 1 NC_004343.2 hypothetical protein 138251 1154068 LB_142 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714686.1 137700 R 189518 CDS NP_714687.1 24217204 1154069 complement(138315..139406) 1 NC_004343.2 lipoprotein qlp42 139406 1154069 LB_143 Leptospira interrogans serovar Lai str. 56601 lipoprotein qlp42 NP_714687.1 138315 R 189518 CDS NP_714688.1 24217205 1154070 complement(139427..139948) 1 NC_004343.2 RNA polymerase ECF-type sigma factor 139948 1154070 LB_144 Leptospira interrogans serovar Lai str. 56601 RNA polymerase ECF-type sigma factor NP_714688.1 139427 R 189518 CDS NP_714690.1 24217207 1153705 141065..141712 1 NC_004343.2 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 141712 1153705 LB_146 Leptospira interrogans serovar Lai str. 56601 peptidoglycan peptidase NP_714690.1 141065 D 189518 CDS NP_714691.1 24217208 1153706 141832..142479 1 NC_004343.2 hypothetical protein 142479 1153706 LB_147 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714691.1 141832 D 189518 CDS NP_714692.1 24217209 1153707 complement(142976..143317) 1 NC_004343.2 hypothetical protein 143317 1153707 LB_148 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714692.1 142976 R 189518 CDS NP_714693.1 24217210 1153708 complement(143871..144494) 1 NC_004343.2 phosphoglycerate mutase 144494 pmgA 1153708 pmgA Leptospira interrogans serovar Lai str. 56601 phosphoglycerate mutase NP_714693.1 143871 R 189518 CDS NP_714694.1 24217211 1153709 complement(144511..145458) 1 NC_004343.2 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 145458 cobD 1153709 cobD Leptospira interrogans serovar Lai str. 56601 cobalamin biosynthesis protein NP_714694.1 144511 R 189518 CDS NP_714695.2 294653563 1153710 complement(145462..148053) 1 NC_004343.2 bifunctional histidinol-phosphate aminotransferase/cobyric acid synthase 148053 cbiP 1153710 cbiP Leptospira interrogans serovar Lai str. 56601 bifunctional histidinol-phosphate aminotransferase/cobyric acid synthase NP_714695.2 145462 R 189518 CDS NP_714696.2 294653562 1153711 complement(148053..148637) 1 NC_004343.2 cobinamide kinase 148637 cobP 1153711 cobP Leptospira interrogans serovar Lai str. 56601 cobinamide kinase NP_714696.2 148053 R 189518 CDS NP_714697.2 294653561 1153712 complement(148613..149296) 1 NC_004343.2 adenosylcobinamide amidohydrolase 149296 1153712 LB_153 Leptospira interrogans serovar Lai str. 56601 adenosylcobinamide amidohydrolase NP_714697.2 148613 R 189518 CDS NP_714698.1 24217215 1153713 complement(149293..150657) 1 NC_004343.2 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 150657 cbiA 1153713 cbiA Leptospira interrogans serovar Lai str. 56601 cobyrinic acid a,c-diamide synthase NP_714698.1 149293 R 189518 CDS NP_714699.1 24217216 1153714 complement(150657..151193) 1 NC_004343.2 cob(I)alamin adenosyltransferase 151193 cobA 1153714 cobA Leptospira interrogans serovar Lai str. 56601 cob(I)alamin adenosyltransferase NP_714699.1 150657 R 189518 CDS NP_714700.1 24217217 1153715 complement(151190..151954) 1 NC_004343.2 precorrin-3 methylase 151954 cbiF 1153715 cbiF Leptospira interrogans serovar Lai str. 56601 precorrin-3 methylase NP_714700.1 151190 R 189518 CDS NP_714701.1 24217218 1153716 complement(151968..153461) 1 NC_004343.2 precorrin methylase 153461 cbiH 1153716 cbiH Leptospira interrogans serovar Lai str. 56601 precorrin methylase NP_714701.1 151968 R 189518 CDS NP_714702.1 24217219 1153717 complement(153458..154615) 1 NC_004343.2 cobalamin biosynthesis protein 154615 cbiG 1153717 cbiG Leptospira interrogans serovar Lai str. 56601 cobalamin biosynthesis protein NP_714702.1 153458 R 189518 CDS NP_714703.2 294653560 1153718 complement(154602..155360) 1 NC_004343.2 precorrin-2 methyltransferase 155360 cobI 1153718 cobI Leptospira interrogans serovar Lai str. 56601 precorrin-2 methyltransferase NP_714703.2 154602 R 189518 CDS NP_714704.1 24217221 1153719 complement(155363..156598) 1 NC_004343.2 precorrin-6Y methylase 156598 cbiE 1153719 cbiE Leptospira interrogans serovar Lai str. 56601 precorrin-6Y methylase NP_714704.1 155363 R 189518 CDS NP_714705.2 294653559 1153720 complement(156595..157257) 1 NC_004343.2 cobalamin biosynthesis precorrin isomerase 157257 cbiC 1153720 cbiC Leptospira interrogans serovar Lai str. 56601 cobalamin biosynthesis precorrin isomerase NP_714705.2 156595 R 189518 CDS NP_714706.1 24217223 1153721 complement(157263..158366) 1 NC_004343.2 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 158366 cbiD 1153721 cbiD Leptospira interrogans serovar Lai str. 56601 cobalt-precorrin-6A synthase NP_714706.1 157263 R 189518 CDS NP_714707.1 24217224 1153722 complement(158370..159119) 1 NC_004343.2 oxidoreductase FAD-binding family protein 159119 1153722 LB_163 Leptospira interrogans serovar Lai str. 56601 oxidoreductase FAD-binding family protein NP_714707.1 158370 R 189518 CDS NP_714708.2 294653558 1153723 complement(159125..159472) 1 NC_004343.2 confirmed by proteomics; hypothetical protein 159472 1153723 LB_164 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714708.2 159125 R 189518 CDS NP_714709.1 24217226 1153724 complement(159517..160686) 1 NC_004343.2 cbiX protein 160686 cbiX 1153724 cbiX Leptospira interrogans serovar Lai str. 56601 cbiX protein NP_714709.1 159517 R 189518 CDS NP_714712.1 24217229 1153727 163043..165166 1 NC_004343.2 hypothetical protein 165166 1153727 LB_167 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714712.1 163043 D 189518 CDS NP_714713.1 24217230 1153728 complement(165172..165744) 1 NC_004343.2 hypothetical protein 165744 1153728 LB_169 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714713.1 165172 R 189518 CDS NP_714714.1 24217231 1153729 165786..167675 1 NC_004343.2 capsular polysaccharide biosynthesis protein 167675 1153729 LB_170 Leptospira interrogans serovar Lai str. 56601 capsular polysaccharide biosynthesis protein NP_714714.1 165786 D 189518 CDS NP_714715.1 24217232 1153730 167668..168138 1 NC_004343.2 hypothetical protein 168138 1153730 LB_171 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714715.1 167668 D 189518 CDS NP_714716.2 294653557 1153731 168162..169745 1 NC_004343.2 hypothetical protein 169745 1153731 LB_172 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714716.2 168162 D 189518 CDS NP_714718.1 24217235 1153733 170187..171074 1 NC_004343.2 putative metalloprotease; heat shock protein HtpX 171074 htpX 1153733 htpX Leptospira interrogans serovar Lai str. 56601 heat shock protein HtpX NP_714718.1 170187 D 189518 CDS NP_714720.1 24217237 1153735 171596..172129 1 NC_004343.2 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 172129 1153735 LB_176 Leptospira interrogans serovar Lai str. 56601 adenine phosphoribosyltransferase NP_714720.1 171596 D 189518 CDS NP_714721.1 24217238 1153736 172167..173681 1 NC_004343.2 serine protease 173681 1153736 LB_177 Leptospira interrogans serovar Lai str. 56601 serine protease NP_714721.1 172167 D 189518 CDS NP_714722.1 24217239 1153737 173696..175279 1 NC_004343.2 serine protease 175279 1153737 LB_178 Leptospira interrogans serovar Lai str. 56601 serine protease NP_714722.1 173696 D 189518 CDS NP_714725.1 24217242 1153740 complement(176651..177883) 1 NC_004343.2 hypothetical protein 177883 1153740 LB_181 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714725.1 176651 R 189518 CDS NP_714726.1 24217243 1153741 complement(177880..179457) 1 NC_004343.2 hypothetical protein 179457 1153741 LB_182 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714726.1 177880 R 189518 CDS NP_714727.1 24217244 1153742 complement(179454..179846) 1 NC_004343.2 FUR family transcriptional regulator 179846 1153742 LB_183 Leptospira interrogans serovar Lai str. 56601 FUR family transcriptional regulator NP_714727.1 179454 R 189518 CDS NP_714730.1 24217247 1153745 181531..182208 1 NC_004343.2 heme oxygenase 182208 1153745 LB_186 Leptospira interrogans serovar Lai str. 56601 heme oxygenase NP_714730.1 181531 D 189518 CDS NP_714731.1 24217248 1153746 182183..183391 1 NC_004343.2 hypothetical protein 183391 1153746 LB_187 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714731.1 182183 D 189518 CDS NP_714733.1 24217250 1153748 complement(183576..184106) 1 NC_004343.2 hypothetical protein 184106 1153748 LB_190 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714733.1 183576 R 189518 CDS NP_714735.1 24217252 1153750 complement(184997..187129) 1 NC_004343.2 confirmed by proteomics; TonB-dependent hemin-binding protein 187129 1153750 LB_191 Leptospira interrogans serovar Lai str. 56601 TonB-dependent hemin-binding protein NP_714735.1 184997 R 189518 CDS NP_714736.2 294653556 1153751 complement(187108..187809) 1 NC_004343.2 hypothetical protein 187809 1153751 LB_192 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714736.2 187108 R 189518 CDS NP_714738.1 24217255 1153753 complement(187834..188412) 1 NC_004343.2 confirmed by proteomics; hypothetical protein 188412 1153753 LB_194 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714738.1 187834 R 189518 CDS NP_714740.2 294653555 1153755 188884..189609 1 NC_004343.2 lipoprotein 189609 1153755 LB_196 Leptospira interrogans serovar Lai str. 56601 lipoprotein NP_714740.2 188884 D 189518 CDS NP_714741.1 24217258 1153756 complement(189622..190395) 1 NC_004343.2 hypothetical protein 190395 1153756 LB_197 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714741.1 189622 R 189518 CDS NP_714742.2 294653554 1153757 complement(190813..191064) 1 NC_004343.2 hypothetical protein 191064 1153757 LB_198 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714742.2 190813 R 189518 CDS NP_714743.1 24217260 1153758 complement(191223..192578) 1 NC_004343.2 outermembrane protein 192578 1153758 LB_199 Leptospira interrogans serovar Lai str. 56601 outermembrane protein NP_714743.1 191223 R 189518 CDS NP_714745.1 24217262 1153760 complement(192836..194458) 1 NC_004343.2 ATP-dependent protease LA 194458 lonA 1153760 lonA Leptospira interrogans serovar Lai str. 56601 ATP-dependent protease LA NP_714745.1 192836 R 189518 CDS NP_714746.1 24217263 1153761 complement(194484..195542) 1 NC_004343.2 queuosine biosynthesis protein 195542 1153761 LB_202 Leptospira interrogans serovar Lai str. 56601 queuosine biosynthesis protein NP_714746.1 194484 R 189518 CDS NP_714747.1 24217264 1153762 195738..197183 1 NC_004343.2 hypothetical protein 197183 1153762 LB_203 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714747.1 195738 D 189518 CDS NP_714748.1 24217265 1153763 197203..198345 1 NC_004343.2 mannosyltransferase A 198345 mtfA 1153763 mtfA Leptospira interrogans serovar Lai str. 56601 mannosyltransferase A NP_714748.1 197203 D 189518 CDS NP_714749.2 294653553 1153764 198350..198922 1 NC_004343.2 hypothetical protein 198922 1153764 LB_205 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714749.2 198350 D 189518 CDS NP_714751.2 294653552 1153766 199355..200740 1 NC_004343.2 hypothetical protein 200740 1153766 LB_207 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714751.2 199355 D 189518 CDS NP_714752.1 24217269 1153767 200812..202224 1 NC_004343.2 alginate o-acetyltransferase 202224 1153767 LB_208 Leptospira interrogans serovar Lai str. 56601 alginate o-acetyltransferase NP_714752.1 200812 D 189518 CDS NP_714753.1 24217270 1153768 202239..203399 1 NC_004343.2 hypothetical protein 203399 1153768 LB_209 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714753.1 202239 D 189518 CDS NP_714754.1 24217271 1153769 203396..204793 1 NC_004343.2 alginate o-acetyltransferase 204793 1153769 LB_210 Leptospira interrogans serovar Lai str. 56601 alginate o-acetyltransferase NP_714754.1 203396 D 189518 CDS NP_714755.1 24217272 1153770 204800..205870 1 NC_004343.2 hypothetical protein 205870 1153770 LB_211 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714755.1 204800 D 189518 CDS NP_714756.1 24217273 1153771 205867..206211 1 NC_004343.2 hypothetical protein 206211 1153771 LB_212 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714756.1 205867 D 189518 CDS NP_714757.1 24217274 1153772 complement(206967..207380) 1 NC_004343.2 biopolymer transport protein 207380 exbD2 1153772 exbD2 Leptospira interrogans serovar Lai str. 56601 biopolymer transport protein NP_714757.1 206967 R 189518 CDS NP_714758.1 24217275 1153773 complement(207377..207904) 1 NC_004343.2 MotA/ExbB proton channel family protein 207904 1153773 LB_214 Leptospira interrogans serovar Lai str. 56601 MotA/ExbB proton channel family protein NP_714758.1 207377 R 189518 CDS NP_714759.1 24217276 1153774 208519..209268 1 NC_004343.2 ubiquinone/menaquinone biosynthesis methlytransferase 209268 ubiE 1153774 ubiE Leptospira interrogans serovar Lai str. 56601 ubiquinone/menaquinone biosynthesis methlytransferase NP_714759.1 208519 D 189518 CDS NP_714761.2 294653551 1153776 209408..211504 1 NC_004343.2 hypothetical protein 211504 1153776 LB_217 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714761.2 209408 D 189518 CDS NP_714762.1 24217279 1153777 211549..212940 1 NC_004343.2 hypothetical protein 212940 1153777 LB_218 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714762.1 211549 D 189518 CDS NP_714763.2 294653550 1153778 complement(212923..215022) 1 NC_004343.2 hypothetical protein 215022 1153778 LB_219 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714763.2 212923 R 189518 CDS NP_714766.1 24217283 1153781 complement(216334..216786) 1 NC_004343.2 hypothetical protein 216786 1153781 LB_222 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714766.1 216334 R 189518 CDS YP_003580117.1 294653597 8998021 complement(216804..216968) 1 NC_004343.2 50S ribosomal protein L33 216968 8998021 LB_222a Leptospira interrogans serovar Lai str. 56601 50S ribosomal protein L33 YP_003580117.1 216804 R 189518 CDS NP_714767.2 294653549 1153782 complement(217223..218071) 1 NC_004343.2 transposase 218071 1153782 LB_223 Leptospira interrogans serovar Lai str. 56601 transposase NP_714767.2 217223 R 189518 CDS NP_714768.2 294653548 1153783 complement(218071..218370) 1 NC_004343.2 transposase 218370 1153783 LB_224 Leptospira interrogans serovar Lai str. 56601 transposase NP_714768.2 218071 R 189518 CDS NP_714769.1 24217286 1153784 219781..222363 1 NC_004343.2 hypothetical protein 222363 1153784 LB_225 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714769.1 219781 D 189518 CDS NP_714770.2 294653547 1153785 222470..222997 1 NC_004343.2 Fimh-like protein 222997 1153785 LB_226 Leptospira interrogans serovar Lai str. 56601 Fimh-like protein NP_714770.2 222470 D 189518 CDS NP_714772.2 294653546 1153787 224115..225338 1 NC_004343.2 DNA-binding protein 225338 1153787 LB_228 Leptospira interrogans serovar Lai str. 56601 DNA-binding protein NP_714772.2 224115 D 189518 CDS NP_714774.1 24217291 1153789 226287..226586 1 NC_004343.2 transposase 226586 1153789 LB_230 Leptospira interrogans serovar Lai str. 56601 transposase NP_714774.1 226287 D 189518 CDS NP_714775.2 294653545 1153790 226628..227428 1 NC_004343.2 transposase 227428 1153790 LB_231 Leptospira interrogans serovar Lai str. 56601 transposase NP_714775.2 226628 D 189518 CDS NP_714776.1 24217293 1153791 complement(228473..228892) 1 NC_004343.2 hypothetical protein 228892 1153791 LB_232 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714776.1 228473 R 189518 CDS NP_714779.1 24217296 1153794 complement(230362..232080) 1 NC_004343.2 EAL family signaling protein 232080 1153794 LB_235 Leptospira interrogans serovar Lai str. 56601 EAL family signaling protein NP_714779.1 230362 R 189518 CDS NP_714781.2 294653544 1153796 complement(232546..233064) 1 NC_004343.2 diguanylate cyclase 233064 1153796 LB_237 Leptospira interrogans serovar Lai str. 56601 diguanylate cyclase NP_714781.2 232546 R 189518 CDS NP_714782.2 294653543 1153797 complement(233176..234147) 1 NC_004343.2 Cache family protein 234147 1153797 LB_238 Leptospira interrogans serovar Lai str. 56601 Cache family protein NP_714782.2 233176 R 189518 CDS NP_714784.2 294653542 1153799 complement(234525..236048) 1 NC_004343.2 diguanylate cyclase 236048 1153799 LB_240 Leptospira interrogans serovar Lai str. 56601 diguanylate cyclase NP_714784.2 234525 R 189518 CDS NP_714785.2 294653541 1153800 236631..239156 1 NC_004343.2 confirmed by proteomics; histidine kinase sensor protein 239156 1153800 LB_241 Leptospira interrogans serovar Lai str. 56601 histidine kinase sensor protein NP_714785.2 236631 D 189518 CDS NP_714786.1 24217303 1153801 complement(239631..240332) 1 NC_004343.2 hypothetical protein 240332 1153801 LB_242 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714786.1 239631 R 189518 CDS NP_714787.1 24217304 1153802 complement(240375..240782) 1 NC_004343.2 hypothetical protein 240782 1153802 LB_243 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714787.1 240375 R 189518 CDS NP_714788.1 24217305 1153803 complement(241065..242069) 1 NC_004343.2 hypothetical protein 242069 1153803 LB_244 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714788.1 241065 R 189518 CDS NP_714789.1 24217306 1153804 complement(242938..244326) 1 NC_004343.2 sodium:solute symporter 244326 1153804 LB_245 Leptospira interrogans serovar Lai str. 56601 sodium:solute symporter NP_714789.1 242938 R 189518 CDS YP_003580118.1 294653595 8998022 244734..245105 1 NC_004343.2 hypothetical protein 245105 8998022 LB_245a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003580118.1 244734 D 189518 CDS NP_714792.1 24217309 1153807 245369..246826 1 NC_004343.2 hypothetical protein 246826 1153807 LB_248 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714792.1 245369 D 189518 CDS NP_714794.1 24217311 1153809 complement(247076..247357) 1 NC_004343.2 hypothetical protein 247357 1153809 LB_250 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714794.1 247076 R 189518 CDS NP_714795.1 24217312 1153810 complement(247354..249318) 1 NC_004343.2 hypothetical protein 249318 1153810 LB_251 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714795.1 247354 R 189518 CDS NP_714796.1 24217313 1153811 complement(249446..250324) 1 NC_004343.2 hypothetical protein 250324 1153811 LB_252 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714796.1 249446 R 189518 CDS NP_714798.1 24217315 1153813 complement(250915..252129) 1 NC_004343.2 sugar transport protein 252129 1153813 LB_254 Leptospira interrogans serovar Lai str. 56601 sugar transport protein NP_714798.1 250915 R 189518 CDS NP_714799.1 24217316 1153814 252642..253931 1 NC_004343.2 4-hydroxybutyrate CoA-transferase 253931 1153814 LB_255 Leptospira interrogans serovar Lai str. 56601 4-hydroxybutyrate CoA-transferase NP_714799.1 252642 D 189518 CDS NP_714801.2 294653540 1153816 254260..254718 1 NC_004343.2 hypothetical protein 254718 1153816 LB_257 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714801.2 254260 D 189518 CDS NP_714802.1 24217319 1153817 254731..257130 1 NC_004343.2 cysteine protease 257130 1153817 LB_258 Leptospira interrogans serovar Lai str. 56601 cysteine protease NP_714802.1 254731 D 189518 CDS NP_714805.1 24217322 1153820 complement(257791..259143) 1 NC_004343.2 hypothetical protein 259143 1153820 LB_261 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714805.1 257791 R 189518 CDS NP_714806.2 294653539 1153821 complement(259249..260622) 1 NC_004343.2 UDP-glucose pyrophosphorylase 260622 galF 1153821 galF Leptospira interrogans serovar Lai str. 56601 UDP-glucose pyrophosphorylase NP_714806.2 259249 R 189518 CDS NP_714807.2 294653538 1153822 complement(260655..261062) 1 NC_004343.2 hypothetical protein 261062 1153822 LB_263 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714807.2 260655 R 189518 CDS NP_714808.1 24217325 1153823 261114..262031 1 NC_004343.2 hypothetical protein 262031 1153823 LB_264 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714808.1 261114 D 189518 CDS NP_714809.2 294653537 1153824 262961..263932 1 NC_004343.2 hypothetical protein 263932 1153824 LB_265 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714809.2 262961 D 189518 CDS NP_714810.1 24217327 1153825 complement(264499..265449) 1 NC_004343.2 hypothetical protein 265449 1153825 LB_266 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714810.1 264499 R 189518 CDS NP_714811.1 24217328 1153826 complement(266341..267492) 1 NC_004343.2 confirmed by proteomics; aminotransferase 267492 1153826 LB_267 Leptospira interrogans serovar Lai str. 56601 aminotransferase NP_714811.1 266341 R 189518 CDS NP_714812.1 24217329 1153827 complement(267503..268372) 1 NC_004343.2 confirmed by proteomics; hypothetical protein 268372 1153827 LB_268 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714812.1 267503 R 189518 CDS NP_714813.1 24217330 1153828 complement(268435..269061) 1 NC_004343.2 hypothetical protein 269061 1153828 LB_269 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714813.1 268435 R 189518 CDS NP_714815.2 294653536 1153830 269149..269511 1 NC_004343.2 permease 269511 1153830 LB_271 Leptospira interrogans serovar Lai str. 56601 permease NP_714815.2 269149 D 189518 CDS NP_714816.1 24217333 1153831 269490..270128 1 NC_004343.2 hypothetical protein 270128 1153831 LB_272 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714816.1 269490 D 189518 CDS NP_714817.1 24217334 1153832 270220..272100 1 NC_004343.2 methylmalonyl-CoA mutase 272100 mcm2 1153832 mcm2 Leptospira interrogans serovar Lai str. 56601 methylmalonyl-CoA mutase NP_714817.1 270220 D 189518 CDS NP_714818.1 24217335 1153833 272097..274295 1 NC_004343.2 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 274295 mcm3 1153833 mcm3 Leptospira interrogans serovar Lai str. 56601 methylmalonyl-CoA mutase NP_714818.1 272097 D 189518 CDS NP_714819.1 24217336 1153834 274308..275363 1 NC_004343.2 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 275363 argK 1153834 argK Leptospira interrogans serovar Lai str. 56601 arginine/ornithine transport system ATPase NP_714819.1 274308 D 189518 CDS NP_714820.1 24217337 1153835 276454..276831 1 NC_004343.2 hypothetical protein 276831 1153835 LB_276 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714820.1 276454 D 189518 CDS NP_714821.1 24217338 1153836 276988..277677 1 NC_004343.2 hypothetical protein 277677 1153836 LB_277 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714821.1 276988 D 189518 CDS NP_714822.1 24217339 1153837 277679..278128 1 NC_004343.2 hypothetical protein 278128 1153837 LB_278 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714822.1 277679 D 189518 CDS NP_714823.2 294653535 1153838 278158..280797 1 NC_004343.2 hypothetical protein 280797 1153838 LB_279 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714823.2 278158 D 189518 CDS NP_714824.2 294653534 1153839 280797..281312 1 NC_004343.2 hypothetical protein 281312 1153839 LB_280 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714824.2 280797 D 189518 CDS NP_714825.1 24217342 1153840 281391..282005 1 NC_004343.2 transport protein ExbB 282005 exbB 1153840 exbB Leptospira interrogans serovar Lai str. 56601 transport protein ExbB NP_714825.1 281391 D 189518 CDS NP_714826.1 24217343 1153841 282095..282499 1 NC_004343.2 transport protein ExbD 282499 exbD3 1153841 exbD3 Leptospira interrogans serovar Lai str. 56601 transport protein ExbD NP_714826.1 282095 D 189518 CDS NP_714827.1 24217344 1153842 282509..283159 1 NC_004343.2 TonB protein 283159 1153842 LB_283 Leptospira interrogans serovar Lai str. 56601 TonB protein NP_714827.1 282509 D 189518 CDS NP_714829.1 24217346 1153844 284342..285136 1 NC_004343.2 hypothetical protein 285136 1153844 LB_285 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714829.1 284342 D 189518 CDS NP_714830.2 294653533 1153845 285199..286800 1 NC_004343.2 confirmed by proteomics; glutamate synthase 286800 gltB2 1153845 gltB2 Leptospira interrogans serovar Lai str. 56601 glutamate synthase NP_714830.2 285199 D 189518 CDS NP_714831.1 24217348 1153846 287136..287864 1 NC_004343.2 hypothetical protein 287864 1153846 LB_287 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714831.1 287136 D 189518 CDS NP_714832.2 294653532 1153847 287870..288301 1 NC_004343.2 hypothetical protein 288301 1153847 LB_288 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714832.2 287870 D 189518 CDS NP_714833.1 24217350 1153848 288435..288866 1 NC_004343.2 hypothetical protein 288866 1153848 LB_289 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714833.1 288435 D 189518 CDS NP_714834.1 24217351 1153849 289094..291637 1 NC_004343.2 two-component hybrid sensor and regulator 291637 1153849 LB_290 Leptospira interrogans serovar Lai str. 56601 two-component hybrid sensor and regulator NP_714834.1 289094 D 189518 CDS NP_714835.1 24217352 1153850 complement(291641..292339) 1 NC_004343.2 3-ketoacyl-acyl carrier protein reductase; 3-oxoacyl-ACP reductase 292339 1153850 LB_291 Leptospira interrogans serovar Lai str. 56601 3-oxoacyl-ACP reductase NP_714835.1 291641 R 189518 CDS NP_714836.1 24217353 1153851 complement(292352..293101) 1 NC_004343.2 sugar aldolase 293101 1153851 LB_292 Leptospira interrogans serovar Lai str. 56601 sugar aldolase NP_714836.1 292352 R 189518 CDS NP_714837.1 24217354 1153852 complement(293103..293636) 1 NC_004343.2 confirmed by proteomics; methionine salvage pathway protein 293636 1153852 LB_293 Leptospira interrogans serovar Lai str. 56601 methionine salvage pathway protein NP_714837.1 293103 R 189518 CDS NP_714838.1 24217355 1153853 complement(293659..294375) 1 NC_004343.2 elongation factor P 294375 1153853 LB_294 Leptospira interrogans serovar Lai str. 56601 elongation factor P NP_714838.1 293659 R 189518 CDS NP_714839.2 294653531 1153854 294465..295634 1 NC_004343.2 transposase 295634 1153854 LB_295 Leptospira interrogans serovar Lai str. 56601 transposase NP_714839.2 294465 D 189518 CDS NP_714841.1 24217358 1153856 297448..298347 1 NC_004343.2 phosphate-binding protein PstS 298347 pstS 1153856 pstS Leptospira interrogans serovar Lai str. 56601 phosphate-binding protein PstS NP_714841.1 297448 D 189518 CDS NP_714842.1 24217359 1153857 298422..299519 1 NC_004343.2 L-lysine 2,3-aminomutase 299519 1153857 LB_298 Leptospira interrogans serovar Lai str. 56601 L-lysine 2,3-aminomutase NP_714842.1 298422 D 189518 CDS NP_714843.2 294653530 1153858 299629..300132 1 NC_004343.2 hypothetical protein 300132 1153858 LB_299 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714843.2 299629 D 189518 CDS NP_714844.2 294653529 1153859 300187..300393 1 NC_004343.2 hypothetical protein 300393 1153859 LB_300 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714844.2 300187 D 189518 CDS NP_714845.2 294653528 1153860 300404..301159 1 NC_004343.2 hypothetical protein 301159 1153860 LB_301 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714845.2 300404 D 189518 CDS NP_714847.2 294653527 1153862 complement(301794..302594) 1 NC_004343.2 transposase 302594 1153862 LB_303 Leptospira interrogans serovar Lai str. 56601 transposase NP_714847.2 301794 R 189518 CDS NP_714848.2 294653526 1153863 complement(302636..302935) 1 NC_004343.2 transposase 302935 1153863 LB_304 Leptospira interrogans serovar Lai str. 56601 transposase NP_714848.2 302636 R 189518 CDS NP_714849.1 24217366 1153864 complement(303423..303917) 1 NC_004343.2 hypothetical protein 303917 1153864 LB_305 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714849.1 303423 R 189518 CDS NP_714851.1 24217368 1153866 complement(304364..304822) 1 NC_004343.2 hypothetical protein 304822 1153866 LB_307 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714851.1 304364 R 189518 CDS NP_714853.2 294653525 1153868 305564..306766 1 NC_004343.2 FimH-like protein 306766 1153868 LB_309 Leptospira interrogans serovar Lai str. 56601 FimH-like protein NP_714853.2 305564 D 189518 CDS NP_714854.1 24217371 1153869 complement(306999..307826) 1 NC_004343.2 orotidine-5'-monophosphate decarboxylase 307826 pyrF 1153869 pyrF Leptospira interrogans serovar Lai str. 56601 orotidine-5'-monophosphate decarboxylase NP_714854.1 306999 R 189518 CDS NP_714855.2 294653524 1153870 complement(307838..308680) 1 NC_004343.2 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 308680 speE2 1153870 speE2 Leptospira interrogans serovar Lai str. 56601 spermidine synthase NP_714855.2 307838 R 189518 CDS NP_714856.1 24217373 1153871 complement(308690..309556) 1 NC_004343.2 hypothetical protein 309556 1153871 LB_312 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714856.1 308690 R 189518 CDS YP_003580119.1 294653596 8998023 complement(309656..310033) 1 NC_004343.2 S-adenosylmethionine decarboxylase 310033 speD 8998023 speD Leptospira interrogans serovar Lai str. 56601 S-adenosylmethionine decarboxylase YP_003580119.1 309656 R 189518 CDS NP_714860.2 294653523 1153875 complement(310509..310997) 1 NC_004343.2 confirmed by proteomics; hypothetical protein 310997 1153875 LB_316 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714860.2 310509 R 189518 CDS NP_714861.1 24217378 1153876 311081..312250 1 NC_004343.2 alanine racemase 312250 1153876 LB_317 Leptospira interrogans serovar Lai str. 56601 alanine racemase NP_714861.1 311081 D 189518 CDS NP_714862.1 24217379 1153877 312301..313446 1 NC_004343.2 hypothetical protein 313446 1153877 LB_318 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714862.1 312301 D 189518 CDS NP_714863.1 24217380 1153878 313467..314378 1 NC_004343.2 hypothetical protein 314378 1153878 LB_319 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714863.1 313467 D 189518 CDS NP_714864.1 24217381 1153879 314375..315166 1 NC_004343.2 hypothetical protein 315166 1153879 LB_320 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714864.1 314375 D 189518 CDS NP_714865.2 294653522 1153880 complement(316122..316721) 1 NC_004343.2 hypothetical protein 316721 1153880 LB_321 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714865.2 316122 R 189518 CDS NP_714866.1 24217383 1153881 complement(316782..319097) 1 NC_004343.2 two-component hybrid sensor and regulator 319097 1153881 LB_322 Leptospira interrogans serovar Lai str. 56601 two-component hybrid sensor and regulator NP_714866.1 316782 R 189518 CDS NP_714867.1 24217384 1153882 319153..319770 1 NC_004343.2 lytic transglycosylase 319770 1153882 LB_323 Leptospira interrogans serovar Lai str. 56601 lytic transglycosylase NP_714867.1 319153 D 189518 CDS NP_714869.1 24217386 1153884 320149..320877 1 NC_004343.2 TetR family transcriptional regulator 320877 1153884 LB_325 Leptospira interrogans serovar Lai str. 56601 TetR family transcriptional regulator NP_714869.1 320149 D 189518 CDS NP_714871.1 24217388 1153886 complement(321522..323795) 1 NC_004343.2 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 323795 acn 1153886 acn Leptospira interrogans serovar Lai str. 56601 aconitate hydratase NP_714871.1 321522 R 189518 CDS NP_714872.1 24217389 1153887 complement(324064..325215) 1 NC_004343.2 outer membrane protein OmpA 325215 ompA 1153887 ompA Leptospira interrogans serovar Lai str. 56601 outer membrane protein OmpA NP_714872.1 324064 R 189518 CDS NP_714873.1 24217390 1153888 complement(325391..326407) 1 NC_004343.2 similar to lysine-tRNA ligase genX - Escherichia coli; lysyl-tRNA synthetase 326407 lysS2 1153888 lysS2 Leptospira interrogans serovar Lai str. 56601 lysyl-tRNA synthetase NP_714873.1 325391 R 189518 CDS NP_714875.1 24217392 1153890 326611..326940 1 NC_004343.2 hypothetical protein 326940 1153890 LB_330 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714875.1 326611 D 189518 CDS NP_714876.2 294653521 1153891 complement(327260..327655) 1 NC_004343.2 hypothetical protein 327655 1153891 LB_332 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714876.2 327260 R 189518 CDS NP_714877.2 294653520 1153892 327884..328609 1 NC_004343.2 two-component response regulator 328609 1153892 LB_333 Leptospira interrogans serovar Lai str. 56601 two-component response regulator NP_714877.2 327884 D 189518 CDS NP_714878.1 24217395 1153893 complement(329177..329836) 1 NC_004343.2 hypothetical protein 329836 1153893 LB_334 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714878.1 329177 R 189518 CDS NP_714879.2 294653519 1153894 complement(329839..330132) 1 NC_004343.2 pterin-4-alpha-carbinolamine dehydratase 330132 phhB 1153894 phhB Leptospira interrogans serovar Lai str. 56601 pterin-4-alpha-carbinolamine dehydratase NP_714879.2 329839 R 189518 CDS NP_714881.1 24217398 1153896 330569..331384 1 NC_004343.2 hypothetical protein 331384 1153896 LB_337 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714881.1 330569 D 189518 CDS NP_714883.1 24217400 1153898 331514..331696 1 NC_004343.2 hypothetical protein 331696 1153898 LB_339 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714883.1 331514 D 189518 CDS NP_714884.2 294653518 1153899 complement(332603..333016) 1 NC_004343.2 hypothetical protein 333016 1153899 LB_340 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714884.2 332603 R 189518 CDS YP_003580120.1 294653598 8998024 333256..333534 1 NC_004343.2 hypothetical protein 333534 8998024 LB_340a Leptospira interrogans serovar Lai str. 56601 hypothetical protein YP_003580120.1 333256 D 189518 CDS NP_714885.1 24217402 1153900 333551..333934 1 NC_004343.2 hypothetical protein 333934 1153900 LB_341 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714885.1 333551 D 189518 CDS NP_714886.1 24217403 1153901 333931..334200 1 NC_004343.2 hypothetical protein 334200 1153901 LB_342 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714886.1 333931 D 189518 CDS NP_714887.1 24217404 1153902 334305..334772 1 NC_004343.2 cytochrome-c oxidase chain III 334772 1153902 LB_343 Leptospira interrogans serovar Lai str. 56601 cytochrome-c oxidase chain III NP_714887.1 334305 D 189518 CDS NP_714889.2 294653517 1153904 complement(335323..336492) 1 NC_004343.2 transposase 336492 1153904 LB_345 Leptospira interrogans serovar Lai str. 56601 transposase NP_714889.2 335323 R 189518 CDS NP_714890.2 294653516 1153905 336845..337144 1 NC_004343.2 transposase 337144 1153905 LB_346 Leptospira interrogans serovar Lai str. 56601 transposase NP_714890.2 336845 D 189518 CDS NP_714892.1 24217409 1153907 337944..338384 1 NC_004343.2 hypothetical protein 338384 1153907 LB_348 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714892.1 337944 D 189518 CDS NP_714894.1 24217411 1153909 complement(339628..340038) 1 NC_004343.2 hypothetical protein 340038 1153909 LB_350 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714894.1 339628 R 189518 CDS NP_714895.1 24217412 1153910 complement(340240..340617) 1 NC_004343.2 outermembrane protein 340617 1153910 LB_351 Leptospira interrogans serovar Lai str. 56601 outermembrane protein NP_714895.1 340240 R 189518 CDS NP_714897.1 24217414 1153912 complement(340871..342331) 1 NC_004343.2 pyruvate kinase 342331 pyk2 1153912 pyk2 Leptospira interrogans serovar Lai str. 56601 pyruvate kinase NP_714897.1 340871 R 189518 CDS NP_714898.1 24217415 1153913 complement(342370..344331) 1 NC_004343.2 hypothetical protein 344331 1153913 LB_354 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714898.1 342370 R 189518 CDS NP_714899.1 24217416 1153914 complement(344344..345393) 1 NC_004343.2 catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; aspartate-semialdehyde dehydrogenase 345393 asd 1153914 asd Leptospira interrogans serovar Lai str. 56601 aspartate-semialdehyde dehydrogenase NP_714899.1 344344 R 189518 CDS NP_714900.1 24217417 1153915 complement(345445..347037) 1 NC_004343.2 hypothetical protein 347037 1153915 LB_356 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714900.1 345445 R 189518 CDS NP_714902.1 24217419 1153917 347587..349152 1 NC_004343.2 hypothetical protein 349152 1153917 LB_358 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714902.1 347587 D 189518 CDS NP_714903.1 24217420 1153918 complement(349123..350586) 1 NC_004343.2 alginate O-acetylation protein 350586 1153918 LB_359 Leptospira interrogans serovar Lai str. 56601 alginate O-acetylation protein NP_714903.1 349123 R 189518 CDS NP_714905.2 294653515 1153920 complement(352294..352674) 1 NC_004343.2 hypothetical protein 352674 1153920 LB_361 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714905.2 352294 R 189518 CDS NP_714906.1 24217423 1153921 complement(352723..353697) 1 NC_004343.2 hypothetical protein 353697 1153921 LB_362 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714906.1 352723 R 189518 CDS NP_714907.2 294653514 1153922 complement(353780..354790) 1 NC_004343.2 hypothetical protein 354790 1153922 LB_363 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714907.2 353780 R 189518 CDS NP_714908.1 24217425 1153923 complement(354792..356162) 1 NC_004343.2 FIS family transcriptional regulator 356162 1153923 LB_364 Leptospira interrogans serovar Lai str. 56601 FIS family transcriptional regulator NP_714908.1 354792 R 189518 CDS NP_714909.1 24217426 1153924 356407..357159 1 NC_004343.2 ParA protein 357159 parA4 1153924 parA4 Leptospira interrogans serovar Lai str. 56601 ParA protein NP_714909.1 356407 D 189518 CDS NP_714910.1 24217427 1153925 357143..357988 1 NC_004343.2 ParB family protein 357988 parB4 1153925 parB4 Leptospira interrogans serovar Lai str. 56601 ParB family protein NP_714910.1 357143 D 189518 CDS NP_714911.1 24217428 1153926 358422..359360 1 NC_004343.2 hypothetical protein 359360 1153926 LB_367 Leptospira interrogans serovar Lai str. 56601 hypothetical protein NP_714911.1 358422 D 189518 CDS