-- dump date 20140619_130312 -- class Genbank::CDS -- table cds_note -- id note YP_122295.1 Similar to chromosome partitioning protein parA YP_122296.1 Some similarity with eukaryotic proteins YP_122297.1 similar to major facilitator superfamily (MFS) transporter YP_122301.1 similar to molybdopterin converting factor 2 (subunit 1) YP_122302.1 similar to thiamine biosynthesis protein YP_122303.1 Weakly similar to conserved hypothetical proteins YP_122304.1 Unknown YP_122305.1 Unknown YP_122306.1 Weakly similar to carbon storage regulator YP_122307.1 Similar to E.coli TraT complement resistance protein YP_122309.1 Similar to putative conjugative transfer protein TraL YP_122310.1 Similar to putative conjugative transfer protein TraE YP_122311.1 Similar to putative conjugative transfer protein TraK YP_122312.1 Similar to putative conjugative transfer protein TraB YP_122313.1 weakly similar to conjugative transfer protein TraC YP_122314.1 Weakly similar to TrbI protein YP_122315.1 similar to conjugative transfer protein TraW YP_122316.1 similar to conjugative transfer protein TraU YP_122317.1 similar to conjugative transfer protein TrbC YP_122318.1 Similar to putative conjugative transfer protein TraN YP_122319.1 type IV secretion system pilus assembly protein; similar to F plasmid TraF YP_122320.1 Weakly similar to putative conjugative transfer protein TrbB YP_122321.1 Similar to conjugative transfer protein TraH YP_122322.1 Similar to sex pilus assembly and mating pair protein TraG YP_122324.1 Similar to conjugative transfer protein TraD YP_122325.1 similar to conjugative transfer protein TraI YP_122326.1 Some similarity with eukaryotic proteins YP_122327.1 Similar to conserved hypothetical protein YP_122328.1 Similar to conserved hypothetical protein YP_122330.1 Similar to antirestriction protein YP_122333.1 Similar to hypothetical protein YP_122335.1 Similar to conserved hypothetical protein YP_122336.1 Similar to site-specific recombinases YP_122340.1 Similar to conserved hypothetical protein YP_122341.1 Similar to conserved hypothetical protein YP_122342.1 Similar to hypothetical protein YP_122343.1 Similar to conserved hypothetical protein YP_122344.1 Similar to helicases YP_122345.1 Similar to uncharacterized protein predicted to be involved in DNA repair YP_122346.1 Similar to transposase YP_122347.1 Simlar to hypothetical protein YP_122348.1 Similar to DNA repair UmuC YP_122349.1 Similar to SOS-response transcriptional repressors YP_122350.1 similar to hypothetical protein YP_125380.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_125384.1 similar to peptidylarginine deiminase and related enzymes YP_125385.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_125386.1 carbon-nitrogen hydrolase family protein YP_125388.1 Similar to host factor-1 protein YP_125389.1 Similar to GTP-binding protein HflX YP_125390.1 Similar to thioredoxin YP_125392.1 Similar to other protein YP_125393.1 Similar to conserved hypothetical protein YP_125394.1 Similar to multidrug resistance efflux pump YP_125397.1 similar to outer membrane efflux proteins YP_125399.1 Similar to Legionella zinc metalloproteinase precursor YP_125400.1 integral membrane protein YP_125401.1 similar to conserved hypothetical protein YP_125402.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_125403.1 membrane protein YP_125405.1 catalyzes the transfer of palmitate to lipid A YP_125406.1 similar to amino acid permease YP_125407.1 similar to low-affinity inorganic phosphate transporter YP_125408.1 similar to ubiquinone biosynthesis protein YP_125411.1 Similar to aminopeptidase YP_125415.1 Similar to conserved hypothetical protein YP_125416.1 Similar to arginine transport system periplasmic binding protein YP_125417.1 Ankyrin repeat protein YP_125418.1 Similar to hypothetical protein YP_125419.1 Similar to conserved hypothetical protein YP_125421.1 Similar to conserved hypothetical protein YP_125425.1 Similar to antibiotic acetyltransferase YP_125426.1 Similar to acetyltransferase YP_125427.1 similar to amino acid permease family proteins YP_125428.1 integral membrane protein YP_125430.1 Similar to unknown protein YP_125431.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_125432.1 Similar to hypothetical protein YP_125434.1 Similar to lysR family transcriptional regulator YP_125438.1 Similar to transcriptional regulator, MerR family YP_125439.1 Similar to glutaredoxin YP_125441.1 Some similarity with eukaryotic protein YP_125442.1 Similar to transposase YP_125443.1 Similar to phage-related integrase YP_125444.1 Similar to hypothetical protein YP_125445.1 Similar to hypothetical protein YP_125446.1 Similar to hypothetical protein YP_125448.1 Similar to conserved hypothetical protein YP_125449.1 Similar to plasmidic transfer origin protein TraK YP_125451.1 Similar to aspartate aminotransferase YP_125452.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_125453.1 regulatory protein (GGDEF and EAL domains) YP_125454.1 similar to other proteins YP_125455.1 Similar to conserved hypothetical protein YP_125456.1 Similar to conserved hypothetical protein YP_125457.1 similar to proline aminopeptidase P II YP_125458.1 similar to 2-octaprenyl-6-methoxyphenol hydroxylase YP_125459.1 similar to monooxygenase YP_125460.1 similar to unknown proteins YP_125461.1 similar to unknown proteins YP_125462.1 secreted protein YP_125463.1 membrane protein YP_125465.1 Similar to arginine-binding periplasmic protein YP_125466.1 conserved hypothetical protein YP_125469.1 Similar to exoribonuclease RNase R YP_125470.1 Similar to RNA methyltransferase YP_125471.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_125472.1 Similar to 5'-nucleotidase YP_125475.1 similar to unknown protein YP_125476.1 Weakly similar to response regulator YP_125478.1 similar to UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase YP_125480.1 3-oxoacyl-[acyl-carrier-protein] synthase YP_125481.1 similar to acetyltransferase YP_125482.1 similar to peptide methionine sulfoxide reductase msrA YP_125483.1 Similar to conserved hypothetical protein, predicted membrane protein YP_125484.1 similar to xanthine/uracil permeases YP_125485.1 Similar to conserved hypothetical protein YP_125488.1 Similar to farnesyl-diphosphate farnesyltransferase (Squalene synthetase) YP_125489.1 Ankyrin repeat protein YP_125490.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_125491.1 Similar to conserved hypothetical protein YP_125492.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_125493.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_125494.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_125496.1 Some similarity with L. pneumophila IcmL/DotI YP_125497.1 Similar to ABC transporter, permease protein YP_125498.1 Similar to ABC transporter, ATP-binding protein YP_125500.1 similar to cytochrome c4 YP_125501.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_125503.1 Highly similar to acetyl-CoA synthetase YP_125504.1 Similar to 3-hydroxyisobutyrate dehydrogenase YP_125505.1 Similar to C. burnetii methylmalonate-semialdehyde dehydrogenase MmsA YP_125506.1 Weakly similar to conserved hypothetical protein YP_125507.1 Some similarity with eukaryotic proteins, coiled-coil protein YP_125508.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_125509.1 hypothetical, similar to hypothetical proteins YP_125510.1 Similar to N-terminal part of ProQ, activator of ProP osmoprotectant transporter (truncated?) YP_125511.1 Similar to hypothetical protein YP_125513.1 Similar to pyruvate kinase II PykA, glucose stimulated YP_125514.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_125516.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_125520.1 Similar to hypothetical protein YP_125521.1 Similar to cytosine-specific DNA methylase YP_125522.1 Similar to DNA mismatch repair endonuclease YP_125523.1 Similar to phage repressor YP_125526.1 similar to carbon storage regulator gene csrA YP_125530.1 traC protein YP_125531.1 component of the type IV secretion system YP_125538.1 component of type IV secretion system YP_125541.1 Similar to transposase YP_125544.1 similar to fatty acid desaturase YP_125545.1 Highly similar to L.pneumophila TraA-like protein YP_125547.1 some similarity with TraD protein YP_125551.1 Similar to conserved hypothetical protein YP_125552.1 Similar to other proteins YP_125554.1 Similar to phage excisionase YP_125555.1 Similar to phage integrase YP_125556.1 Similar to predicted ATPase YP_125557.1 Similar to predicted Rossmann fold nucleotide-binding protein involved in DNA uptake YP_125559.1 Similar to hypothetical protein YP_125560.1 Similar to transposase YP_125561.1 Similar to transposase YP_125562.1 Similar to transposase YP_125563.1 Some similarity with SidC YP_125566.1 Similar to transposase YP_125567.1 Similar to virulence protein YP_125568.1 Similar to transposase YP_125569.1 Similar to transposase and inactivated derivatives YP_125570.1 Similar to transposase YP_125571.1 Similar to transposase YP_125572.1 Similar to hypothetical protein YP_125573.1 Similar to hypothetical protein YP_125575.1 Some similarity with nucleoside hydrolase YP_125576.1 Similar to conserved hypothetical protein YP_125577.1 Similar to hypothetical protein YP_125580.1 Similar to conserved hypothetical protein YP_125581.1 Similar to aminotransferase YP_125585.1 Similar to ABC-type antimicrobial peptide transport system, ATPase component YP_125586.1 Similar to ABC-type antimicrobial peptide transport system, permease component YP_125587.1 Similar to membrane protein YP_125588.1 regulatory protein (GGDEF domain) YP_125589.1 regulatory protein (EAL domain) YP_125590.1 Similar to type I methionine aminopeptidase proteins YP_125591.1 Similar to conserved hypothetical protein YP_125592.1 Predicted membrane protein YP_125594.1 Similar to conserved hypothetical protein YP_125595.1 Similar to outer membrane protein YP_125596.1 Similar to conserved hypothetical protein YP_125597.1 Similar to conserved hypothetical protein YP_125598.1 similar to conserved hypothetical protein YP_125599.1 similar to unknown proteins YP_125600.1 Similar to hypothetical protein YP_125601.1 Similar to C-terminal part of paraquat-inducible protein YP_125602.1 Similar to hypothetical ABC transporter (permease) YP_125603.1 Protein with a F-box domain YP_125604.1 Similar to transcriptional regulator (LysR family) YP_125605.1 Similar to pyoverdine biosynthesis protein PvcA YP_125606.1 Similar to pyoverdine biosynthesis protein PvcB YP_125607.1 similar to FAD monooxygenase, PheA/TfdB family YP_125608.1 some similarity with transporters YP_125609.1 Catalyzes the formation of malnoyl-CoA, which in turn controls the rate of fatty acid metabolism YP_125610.1 some similarity with methyltransferases (deletion of the N-terminal part, hypothetical start codon) YP_125611.1 Similar to protease heat shock protein YP_125614.1 Similar to conserved hypothetical protein YP_125615.1 Similar to predicted acyl-CoA transferases YP_125620.1 similar to conserved hypothetical protein YP_125621.1 similar to cytochrome d ubiquinol oxidase subunit I YP_125622.1 similar to cytochrome d ubiquinol oxidase subunit II YP_125623.1 similar to conserved hypothetical protein YP_125624.1 membrane protein YP_125625.1 Similar to hypothetical protein YP_125626.1 similar to oxydoreductase YP_125627.1 Similar to conserved hypothetical protein YP_125629.1 similar to serine/threonine-protein kinase (conserved domain) YP_125632.1 Similar to sensory protein (eukaryotic) YP_125633.1 similar to deoxyribodipyrimidine photolyase phrB YP_125634.1 similar to membrane protein LrgB YP_125635.1 Predicted membrane protein, similar to conserved hypothetical protein LrgA YP_125636.1 similar to transcriptional regulator, lysR family YP_125637.1 Similar to conserved hypothetical protein YP_125638.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_125640.1 similar to unknown protein YP_125641.1 similar to conserved hypothetical protein YP_125642.1 similar to unknown protein YP_125643.1 Similar to NADH-ubiquinone oxidoreductase chain 5 YP_125644.1 similar to transcriptional regulator, lysR family YP_125645.1 Similar to toxin secretion ABC transporter ATP-binding protein YP_125646.1 Similar to RND efflux membrane fusion proteins YP_125647.1 similar to outer membrane component of multidrug efflux pump YP_125650.1 regulatory protein (GGDEF domain) YP_125651.1 similar to cation transport ATPase YP_125652.1 Similar to Fe2+/Zn2+ uptake regulation proteins YP_125656.1 Similar to conserved hypothetical protein YP_125658.1 Similar to hydrolase YP_125659.1 similar to betaine aldehyde dehydrogenase BetB YP_125660.1 similar to 4-aminobutyrate aminotransferase YP_125662.1 similar to glutaminase YP_125663.1 Similar to D-3 phosphoglycerate dehydrogenase SerA YP_125664.1 Similar to dehydrogenase YP_125665.1 similar to oxydoreductase YP_125666.1 similar to C-terminal part of conserved hypothetical protein YP_125669.1 similar to arsenate reductase YP_125670.1 similar to fatty acid desaturase YP_125671.1 similar to ATP-dependent RNA helicase RhlE YP_125672.1 Similar to unknown protein; membrane protein YP_125673.1 similar to acetyltransferase YP_125675.1 similar to outer membrane protein YP_125676.1 N-terminal part similar to N-terminal part of conserved hypothetical protein YP_125677.1 similar to multidrug resistance proteins YP_125681.1 Similar to C-terminal part of DNA polymerase, bacteriophage-type YP_125682.1 Similar to transporter, MFS family YP_125683.1 weakly similar to amidase YP_125684.1 Similar to multicopper oxidase YP_125686.1 Similar to magnesium and cobalt transport proteins YP_125687.1 Similar to predicted hydrolase YP_125688.1 similar to conserved hypothetical protein YP_125689.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_125691.1 similar to conserved hypothetical protein YP_125692.1 Similar to transporter of the major facilitator superfamily (MFS) YP_125693.1 Similar to transcriptional regulators YP_125695.1 Unknown YP_125696.1 regulatory protein (GGDEF domain) YP_125697.1 Similar to two-component sensor histidine kinase YP_125698.1 Similar to conserved hypothetical protein YP_125699.1 similar to transcriptional regulator lysR family YP_125700.1 similar to amino acid transporter YP_125701.1 Some similarity with eukaryotic proteins YP_125702.1 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate YP_125705.1 similar to oxidoreductase, short chain dehydrogenase/reductase family YP_125706.1 signal peptide predicted YP_125707.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_125708.1 similar to conserved hypothetical protein YP_125709.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_125710.1 Similar to conserved hypothetical protein YP_125711.1 Weakly similar to chromate transport protein YP_125713.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_125715.1 similar to nucleotidyltransferase family protein YP_125716.1 Similar to conserved hypothetical protein YP_125717.1 Similar to organic solvent tolerance protein YP_125718.1 Similar to peptidyl-prolyl cis-trans isomerase SurA YP_125721.1 similar to eukaryotic proteins YP_125722.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_125723.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_125725.1 binds directly to 23S ribosomal RNA YP_125726.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_125727.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_125728.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_125729.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_125730.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_125731.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_125732.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_125733.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_125734.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_125735.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_125736.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_125737.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_125738.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_125739.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_125740.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_125741.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_125742.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_125743.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_125744.1 one of the stabilizing components for the large ribosomal subunit YP_125745.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_125746.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_125747.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_125748.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_125749.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the Legionella proteins appear to contain the zinc-binding motif YP_125750.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_125751.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_125752.1 binds 5S rRNA along with protein L5 and L25 YP_125753.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_125754.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_125755.1 late assembly protein YP_125756.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_125757.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_125758.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_125759.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_125760.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_125761.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_125762.1 is a component of the macrolide binding site in the peptidyl transferase center YP_125764.1 Similar to major facilitator superfamily (MFS)transporter YP_125765.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_125766.1 similar to acyl carrier proteins YP_125767.1 similar to hydroxymyristoyl-(acyl carrier protein) dehydratase YP_125768.1 similar to 3-oxoacyl-[acyl-carrier-protein]synthase II YP_125769.1 similar to 3-oxoacyl-[acyl-carrier-protein] synthase beta chain YP_125770.1 similar to lipid A biosynthesis acyltransferase YP_125773.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_125774.1 lipopeptide YP_125775.1 Unknown YP_125776.1 similar to phospholipase/carboxylesterase YP_125777.1 similar to conserved hypothetical proteins YP_125778.1 similar to conserved hypothetical proteins YP_125779.1 similar to other protein YP_125781.1 similar to choline dehydrogenase (N-terminal part) YP_125782.1 regulatory protein (GGDEF domain) YP_125786.1 similar to conserved hypothetical proteins YP_125787.1 similar to conserved hypothetical proteins YP_125788.1 similar to hypothetical protein modification enzyme YP_125790.1 similar to hypothetical proteins YP_125791.1 Similar to hyperosmotically inducible periplasmic proteins YP_125794.1 similar to LemA from Coxiella burnetii YP_125795.1 metalloprotease YP_125796.1 Highly similar to ABC-type multidrug transport system, permease component YP_125797.1 Highly similar to ATP-binding component of ABC transporter YP_125800.1 similar to prolyl/lysyl hydroxylase YP_125801.1 Weakly similar to Zinc metalloprotease YP_125804.1 similar to methylated-DNA-protein-cysteine S-methyltransferase YP_125805.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_125806.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_125807.1 similar to 16S rRNA processing protein RimM YP_125808.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_125809.1 similar to signal recognition particle protein Ffh YP_125811.1 Ankyrin repeat protein YP_125812.1 similar to amino acid antiporter YP_125814.1 similar to conserved hypothetical proteins YP_125816.1 Predicted membrane protein, similar to hypothetical proteins YP_125817.1 similar to transmembrane proteins YP_125818.1 similar to conserved hypothetical proteins YP_125819.1 similar to hypothetical proteins YP_125820.1 similar to conserved hypothetical proteins, hypothetical cytochrome oxidase assembly protein YP_125821.1 converts protoheme IX and farnesyl diphosphate to heme O YP_125822.1 similar to hypothetical proteins YP_125823.1 similar to ribosomal protein S6 modification enzyme YP_125824.1 similar to hypothetical proteins YP_125825.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_125826.1 similar to 6-phosphogluconolactonase YP_125827.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_125828.1 similar to glucokinase YP_125829.1 similar to 2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase YP_125830.1 similar to sugar transport protein YP_125831.1 similar to eukaryotic glucoamylase precursor (Glucan 1,4-alpha-glucosidase) YP_125832.1 similar to transcriptional regulator (XRE-family) YP_125833.1 similar to hypothetical proteins YP_125834.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_125836.1 similar to N-terminus of Diadenosine tetraphosphate (Ap4A) hydrolase YP_125837.1 similar to hypothetical proteins YP_125838.1 similar to outer membrane proteins YP_125839.1 similar to Multidrug resistance efflux pump YP_125840.1 Unknown YP_125841.1 similar to hypothetical proteins YP_125842.1 transcriptional regulator YP_125843.1 Unknown YP_125844.1 similar to hypothetical protein YP_125845.1 ankyrin repeat protein YP_125868.1 involved in de novo purine biosynthesis YP_125869.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_125872.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_125873.1 catalyzes the formation of oxaloacetate from pyruvate YP_125875.1 lipase LipA (L.pneumophila) YP_125876.1 similar to conserved hypothetical proteins YP_125877.1 Similar to fructose-bisphosphate aldolase YP_125878.1 Similar to ferredoxin--NADP reductase YP_125880.1 conserved hypothetical protein YP_125881.1 similar to CDP-diacylglycerol-serine O-phosphatidyltransferase (Phosphatidylserine synthase) YP_125882.1 similar to sugar transport PTS phosphocarrier protein Hpr YP_125883.1 similar to sigma-54 modulation protein YP_125884.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_125885.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_125886.1 required for 70S ribosome assembly YP_125887.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_125888.1 similar to endo-1,4-beta-glucanase (hypothetical) YP_125889.1 Protein with ankyrin domain YP_125892.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_125893.1 similar to hypothetial proteins YP_125894.1 similar to transcriptional regulator of arginine metabolism YP_125895.1 similar to glutamine-binding periplasmic protein precursor YP_125896.1 similar to amino acid ABC transporter permease YP_125897.1 similar to amino acid (glutamine) ABC transporter (ATP-binding protein) YP_125898.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_125899.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_125901.1 similar to adenosine deaminase YP_125902.1 similar to ABC-type branched-chain amino acid transport systems, periplasmic component YP_125903.1 similar to carboxy-terminal protease family protein YP_125904.1 similar to membrane-bound metallopeptidase YP_125905.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_125907.1 phospholipase C YP_125908.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_125910.1 similar to membrane-associated Zn-dependent protease EcfE YP_125911.1 similar to protective surface antigen YP_125912.1 similar to outer membrane proteins YP_125914.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_125915.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_125916.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_125917.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_125920.1 Weakly similar to eukaryotic phytanoyl coA dioxygenase YP_125922.1 similar to oxidoreductase,aldo/keto reductase family,related to diketogulonate reductase YP_125924.1 similar to methyltransferase YP_125925.1 Similar to adenosine phosphosulfate (APS) kinase YP_125926.1 similar to acetyltransferase, GNAT family YP_125927.1 similar to unknown protein YP_125928.1 Similar to transposase YP_125929.1 Similar to transposase, truncated YP_125930.1 similar to cation transport ATPase YP_125931.1 conserved hypothetical protein, some similarity with stress proteins YP_125932.1 Similar to potassium efflux transporter YP_125933.1 Similar to transposase YP_125934.1 Similar to transposase YP_125935.1 Unknown virulence protein YP_125937.1 similar to conserved hypothetical protein YP_125941.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_125942.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_125944.1 catalyzes the interconversion of succinyl-CoA and succinate YP_125946.1 Similar to pyridoxine 5'-phosphate oxidase YP_125949.1 similar to major facilitator superfamily (MFS) transport proteins YP_125950.1 C-terminal part similar to unknown virulence protein YP_125951.1 similar to DNA-binding proteins Fis YP_125953.1 similar to outer membrane lipoproteins YP_125954.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_125955.1 Similar to gamma-glutamyltranspeptidase YP_125957.1 similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_125958.1 similar to suppressor of groEL YP_125959.1 Similar to aminoglycoside phosphotransferase YP_125960.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_125961.1 similar to hypothetical proteins YP_125962.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_125964.1 similar to fatty acid desaturase YP_125966.1 similar to acetoacetyl-CoA reductase YP_125967.1 similar to acetoacetyl-CoA reductase YP_125968.1 similar to hypothetical proteins YP_125970.1 similar to hypothetical proteins YP_125971.1 similar to Bacillus subtilis spore maturation protein B YP_125972.1 similar to uncharacterized membrane protein, similar to Bacillus subtilis spore maturation protein B YP_125973.1 similar to membrane proteins related to metalloendopeptidases YP_125974.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_125975.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_125976.1 Similar to conserved hypothetical protein YP_125977.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_125978.1 catalyzes the formation of inosine from adenosine YP_125980.1 Similar to phosphate permease YP_125981.1 Similar to conserved hypothetical protein YP_125982.1 Similar to hypothetical protein YP_125983.1 Similar to conserved hypothetical protein YP_125984.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_125985.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_125987.1 Similar to competence protein comM YP_125988.1 Similar to conserved hypothetical protein YP_125990.1 similar to 5-formyltetrahydrofolate cyclo-ligase YP_125991.1 similar to unknown protein YP_125992.1 similar to aminodeoxychorismate lyase (PabC) YP_125993.1 Similar to conserved hypothetical protein. Predicted membrane protein. YP_125994.1 Similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_125995.1 similar to unknown protein YP_125997.1 similar to poly-beta-hydroxybutyrate synthase YP_125998.1 Similar to conserved hypothetical protein YP_125999.1 with SufCD activates cysteine desulfurase SufS YP_126000.1 Similar to ABC transporter ATP-binding protein YP_126001.1 Similar ABC transporter, permease component YP_126002.1 similar to cysteine desulfurase and to selenocysteine lyase YP_126003.1 NifU protein family, possibly involved in the formation or repair of [Fe-S] clusters YP_126004.1 Similar to conserved hypothetical protein YP_126005.1 similar to lysyl-tRNA synthetase YP_126006.1 Similar to methyltransferase YP_126007.1 similar to a domain of alanyl-tRNA synthetase YP_126008.1 Similar to major facilitator family transporter YP_126009.1 similar to unknown protein YP_126010.1 similar to alcohol dehydrogenase YP_126012.1 similar to hypothetical protein YP_126013.1 Similar to Na+/H+ antiporters YP_126014.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_126015.1 similar to unknown protein YP_126016.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_126017.1 Similar to L.pneumophila major outer membrane protein YP_126018.1 Similar to 3-methyladenine-DNA glycosylase I YP_126021.1 similar to probable transmembrane protein YP_126022.1 Similar to hypothetical protein, predicted membrane protein YP_126024.1 Similar to unknown eukaryotic proteins YP_126025.1 weakly similar with DNA uptake/competence proteins YP_126026.1 competence and adherence associated protein -CAP- YP_126027.1 weakly similar to type 4 fimbrial biogenesis protein PilY1 YP_126028.1 Similar to Tfp pilus assembly protein PilX YP_126029.1 Similar to Tfp pilus assembly protein PilW YP_126030.1 weakly similar with pre-pilin leader sequence YP_126031.1 similar to type-4 fimbrial pilin related protein YP_126032.1 Similar to peptidoglycan GlcNAc deacetylase proteins YP_126034.1 similar to hypothetical proteins YP_126035.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_126036.1 Similar to major facilitator family transporter YP_126037.1 Similar to major facilitator family transporter YP_126038.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_126039.1 heat shock protein involved in degradation of misfolded proteins YP_126040.1 heat shock protein involved in degradation of misfolded proteins YP_126042.1 similar to tRNA processing ribonuclease BN YP_126044.1 Similar to flavoprotein WrbA (Trp repressor binding protein) YP_126045.1 Similar to conserved hypothetical protein YP_126046.1 Similar to exodeoxyribonuclease YP_126047.1 Similar to exodeoxyribonuclease III XthA YP_126048.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_126049.1 Similar to NADP-dependent malic enzyme YP_126050.1 Similar to major facilitator family transporter YP_126051.1 Similar to major facilitator family transporter YP_126053.1 Similar to tyrosine-specific transport protein YP_126054.1 Similar to tyrosine-specific transport protein YP_126055.1 lipoprotein, similar to other proteins YP_126057.1 similar to membrane protein YP_126058.1 Similar to ABC-type multidrug transport, ATP-binding protein YP_126059.1 Similar to ABC transporter (permease) YP_126060.1 Similar to ABC transporter permease protein, hypothetical start codon YP_126061.1 similar to outer membrane efflux protein YP_126062.1 Similar to soluble lytic murein transglycosylase YP_126064.1 Predicted membrane protein YP_126065.1 Similar to conserved hypothetical protein YP_126066.1 Similar to conserved hypothetical protein YP_126067.1 Similar to hypothetical protein YP_126068.1 Similar to predicted esterae YP_126069.1 similar to NADH-ubiquinone oxidoreductase YP_126070.1 converts acetoacetate to acetone and carbon dioxide YP_126071.1 Similar to unknown protein YP_126072.1 similar to adenylate cyclase YP_126073.1 Similar to conserved hypothetical protein YP_126074.1 similar to conserved hypothetical protein YP_126076.1 similar to amino acid ABC transporter, periplasmic binding protein. YP_126077.1 similar to glutamine synthetase adenylyltransferase YP_126078.1 Similar to conserved hypothetical protein YP_126081.1 similar to ABC-type multidrug transport system, ATPase component YP_126082.1 similar to ABC transporter, permease component YP_126083.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_126084.1 Similar to thiol:disulfide interchange protein DsbD YP_126085.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_126086.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_126087.1 Weakly similar to DNA-binding ferritin-like protein (oxidative damage protectant) YP_126088.1 Similar to conserved hypothetical protein, predicted membrane protein YP_126089.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_126090.1 Similar to ABC transporter ATP-binding protein YP_126092.1 LigA protein(Legionella Infectivity Gene A) YP_126093.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_126094.1 Ankyrin repeat protein YP_126096.1 Similar to inorganic transporter and to carbonic anhydrase (bi-functional) YP_126097.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_126098.1 similar to outer membrane protein TolC YP_126099.1 Similar to L-isoaspartate carboxylmethyltransferase protein pcm YP_126100.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_126101.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_126102.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_126103.1 Similar to enhanced entry protein EnhA YP_126104.1 Similar to conserved hypothetical protein, predicted membrane protein YP_126105.1 Similar to conserved hypothetical protein, predicted membrane protein YP_126106.1 probable outer membrane protein YP_126107.1 weakly similar to L. pneumophila IcmL protein YP_126108.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_126109.1 Similar to oxidoreductase YP_126110.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_126111.1 Similar to conserved hypothetical protein YP_126112.1 Similar to transporters YP_126113.1 Similar to two-component sensor histidine kinase YP_126114.1 Similar to two component transcriptional regulator YP_126117.1 Similar to proton/sodium-glutamate symport protein YP_126118.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_126119.1 Highly similar to multidrug efflux transporter YP_126120.1 Similar to efflux transporter, RND family YP_126123.1 Similar to predicted periplasmic or secreted lipoprotein YP_126124.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_126125.1 similar to unknown proteins YP_126126.1 Similar to N utilization substance protein B homolog YP_126129.1 Similar to predicted permease YP_126130.1 Some similarity with outer surface protein YP_126131.1 weakly similar to outer membrane protein YP_126133.1 Similar to glutamine-dependent NAD(+) synthetase YP_126134.1 Similar to DNA/RNA helicases, superfamily II, SNF2 family YP_126135.1 Similar to conserved hypothetical protein YP_126137.1 similar to alanine racemase 1 YP_126138.1 similar to surface antigens (17 kDa) YP_126139.1 Similar to conserved hypothetical protein YP_126140.1 Similar to unknown proteins YP_126141.1 similar to unknown proteins YP_126142.1 regulatory protein (GGDEF domain) YP_126143.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_126144.1 similar to conserved hypothetical protein YP_126147.1 Similar to LPS biosynthesis protein YP_126148.1 Similar to imidazole glycerol phosphate synthase subunit HisF YP_126149.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_126153.1 Similar to acetyl transferase YP_126154.1 similar to polysaccharide biosynthesis protein YP_126160.1 similar to NAD dependent epimerase/dehydratase family protein YP_126162.1 Similar to transposase YP_126163.1 Similar to transposase YP_126164.1 Similar to hypothetical protein YP_126165.1 Similar to molybdopterin cofactor synthesis protein A YP_126168.1 Similar to sialic acid synthase YP_126170.1 Similar to hypothetical protein YP_126176.1 similar to glycosyltransferase YP_126177.1 similar to glycosyl transferase YP_126178.1 similar to glyoxalase II YP_126179.1 affects carbohydrate metabolism; has regulatory role in many processes YP_126180.1 Similar to O-antigen acetylase YP_126182.1 Similar to phosphopantetheinyl transferase YP_126183.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_126184.1 Similar to cell cycle protein MesJ YP_126186.1 Similar to alginate o-acetyltransferase AlgI YP_126187.1 Similar to L-serine dehydratase YP_126189.1 Similar to AmpG protein YP_126190.1 similar to unknown proteins YP_126191.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_126193.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_126194.1 Similar to sulfate transporter YP_126195.1 Similar to acyl-CoA dehydrogenase YP_126196.1 Similar to hydrolase YP_126197.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_126198.1 Similar to Na(+)/H(+) antiporter YP_126200.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_126201.1 Similar to succinyl-diaminopimelate desuccinylase YP_126202.1 Similar to other proteins YP_126203.1 functions in MreBCD complex in some organisms YP_126204.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_126206.1 Similar to ribosomal large subunit pseudouridine synthase (Pseudouridylate synthase) YP_126209.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_126211.1 Similar to lipopolysaccharide biosynthesis glycosyltransferase YP_126212.1 Similar to O-antigen biosynthesis protein YP_126214.1 Similar to uncharacterized membrane protein YP_126215.1 similar to peptidase proteins YP_126216.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_126217.1 similar to outer membrane protein YP_126218.1 similar to unknown proteins YP_126219.1 regulatory protein (GGDEF and EAL domains) YP_126221.1 Similar to flavin-containing monooxygenases YP_126222.1 similar to oxidoreductases, short-chain dehydrogenase/reductase family YP_126223.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_126224.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_126225.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_126226.1 Similar to ABC transporter, ATP-binding protein YP_126227.1 Similar to conserved hypothetical protein YP_126228.1 Similar to conserved hypothetical protein YP_126229.1 Similar to conserved hypothetical protein YP_126230.1 Similar to arabinose 5-phosphate isomerase YP_126231.1 Similar to ABC transporter, ATP-binding protein YP_126232.1 Similar to permease of ABC transporter YP_126233.1 similar to unknown protein YP_126234.1 similar to unknown protein YP_126235.1 weakly similar to anti-anti-sigma factor YP_126236.1 Similar to conserved hypothetical protein YP_126237.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_126238.1 Similar to conserved hypothetical protein YP_126239.1 Highly similar to ABC transporter, ATP-binding protein YP_126240.1 Similar to conserved hypothetical protein YP_126241.1 similar to membrane-fusion protein YP_126245.1 SohB; periplasmic protein; member of the peptidase S49 family YP_126246.1 ATP-binding protein; required for proper cytochrome c maturation YP_126250.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_126254.1 similar to cytochrome c-type biogenesis protein YP_126255.1 Similar to conserved hypothetical protein YP_126256.1 Similar to outer membrane lipoprotein YP_126257.1 Similar to 3-methyladenine DNA glycosylase YP_126258.1 similar to ATP-dependent DNA helicase RecQ YP_126259.1 similar to acyl-CoA dehydrogenase YP_126260.1 similar to enoyl-CoA hydratase/carnithine racemase YP_126261.1 similar to enoyl-CoA hydratase/isomerase family protein YP_126264.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_126269.1 Similar to uncharacterized proteins YP_126271.1 regulatory protein (GGDEF domain) YP_126273.1 predicted transmembrane protein YP_126275.1 similar to glycosyl hydrolase YP_126276.1 Similar to amino acid transporter YP_126277.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_126278.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_126279.1 Similar to acetyltransferase YP_126280.1 Similar to cystathionine beta-lyase YP_126281.1 regulatory protein (GGDEF and EAL domains) YP_126282.1 Similar to kynurenine 3-monooxygenase YP_126283.1 Similar to unknown proteins YP_126284.1 Similar to eukaryotic cytokinin oxidase YP_126287.1 Similar to sodium/calcium antiporter YP_126289.1 Similar to A/G-specific adenine glycosylase YP_126290.1 Similar to conserved hypothetical protein YP_126293.1 Similar to hypothetical protein YP_126294.1 Similar to protease YP_126295.1 Similar to hypothetical protein YP_126296.1 Similar to 3-hydroxyacyl-CoA dehydrogenase type II YP_126297.1 Similar to unknown proteins YP_126298.1 Similar to negative regulator of flagellin synthesis (Anti-sigma-28 factor) YP_126299.1 required for the assembly of the flagellar basal body P-ring YP_126300.1 similar to cytochrome c-type protein YP_126301.1 Similar to enhanced entry protein EnhA YP_126302.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_126303.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_126304.1 Similar to S-adenosyl-methyltransferase MraW YP_126305.1 similar to cell division protein FtsL YP_126307.1 Similar to UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase YP_126308.1 similar to erythronate-4-phosphate dehydrogenase YP_126310.1 similar to unknown protein YP_126314.1 Similar to alanine dehydrogenase YP_126315.1 Similar to peptidoglycan synthetase; penicillin-binding protein 1A YP_126322.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_126323.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_126324.1 similar to unknown protein YP_126325.1 Similar to universal stress protein A YP_126327.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_126328.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_126329.1 Similar to keto-hydroxyglutarate aldolase YP_126332.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_126334.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_126335.1 Similar to 2-oxoglutarate ferredoxin oxidoreductase alpha subunit YP_126336.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_126337.1 Predicted membrane protein, similar to transporter YP_126338.1 Similar to hydrolase YP_126340.1 Similar to conserved hypothetical protein YP_126341.1 Similar to long-chain-fatty-acid--CoA ligase YP_126343.1 Similar to conserved hypothetical protein YP_126345.1 Similar to hypothetical protein YP_126347.1 Similar to extracellular solute-binding protein YP_126348.1 Similar to ABC transporter, permease protein YP_126349.1 Similar to ABC transporter, permease protein YP_126352.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate YP_126353.1 Similar to LphB protein YP_126354.1 Similar to nucleoside-diphosphate sugar epimerases YP_126357.1 Similar to amino acid (lysine) permease YP_126358.1 Similar to eukaryotic ectonucleoside triphosphate diphosphohydrolase (apyrase) YP_126359.1 Similar to conserved hypothetical protein YP_126361.1 Similar to conserved hypothetical protein YP_126362.1 Similar to UmuD protein YP_126363.1 similar to DNA repair proteins UmuC YP_126364.1 hypothetical gene YP_126366.1 hypothetical gene YP_126367.1 Similar to antirestriction protein YP_126368.1 similar to single-stranded DNA-binding protein (ssb) YP_126371.1 Weakly similar to integrase YP_126373.1 Some similarity with RNA-directed DNA polymerase YP_126374.1 Similar to conserved hypothetical protein YP_126377.1 membrane protein similar to conserved hypothetical protein YP_126378.1 Similar to conserved hypothetical protein; signal peptide predicted YP_126379.1 Similar to conserved hypothetical protein YP_126380.1 similar to unknown proteins YP_126381.1 similar to unknown proteins YP_126382.1 Similar to conserved hypothetical protein YP_126383.1 Similar to conserved hypothetical protein YP_126384.1 Similar to conserved hypothetical protein YP_126389.1 C-terminal part similar to C-terminal part of conserved hypothetical protein YP_126390.1 Similar to conserved hypothetical protein YP_126391.1 similar to unknown protein YP_126393.1 Similar to PilL protein YP_126394.1 Similar to carbon storage regulator YP_126395.1 Similar to Legionella LvrB protein YP_126396.1 Similar to LvrA protein YP_126397.1 Similar to phage repressor YP_126398.1 Similar to lipoprotein YP_126399.1 Similar to conserved hypothetical protein YP_126400.1 Similar to cation efflux system protein CzcC YP_126401.1 Similar to cation efflux system protein CzcB YP_126404.1 Weakly similar to transcriptional regulator YP_126405.1 similar to cation transport ATPase YP_126408.1 Similar to transcriptional regulator, SinR family YP_126409.1 Similar to conserved hypothetical protein YP_126410.1 regulatory protein (GGDEF and EAL domains) YP_126411.1 Similar to acetoacetyl-CoA reductase YP_126412.1 Similar to cold shock protein YP_126413.1 Similar to EnhC protein, contains 7 sel-1 domains YP_126414.1 Similar to major facilitator family transporter YP_126415.1 Similar to peptide deformylase YP_126419.1 Similar to transcriptional regulator YP_126420.1 Similar to prophage integrase YP_126422.1 Some similarity with helicase proteins YP_126424.1 Weakly similar to chemotaxis motB protein YP_126427.1 Similar to conserved hypothetical protein YP_126430.1 Similar to hypothetical protein YP_126431.1 hypothetical gene YP_126432.1 Similar to transposase YP_126433.1 Similar to transposase YP_126437.1 Similar to conserved hypothetical protein YP_126438.1 Similar to DNA-damage-inducible protein J YP_126439.1 Similar to phage-related integrase proteins YP_126441.1 Similar to conserved hypothetical protein YP_126445.1 Weakly similar to DNA-binding protein YP_126446.1 Similar to plasmid maintenance system killer protein YP_126447.1 Similar to plasmid maintenance system antidote protein YP_126449.1 Similar to beta-phosphoglucomutase YP_126452.1 Similar to other protein YP_126456.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_126458.1 membrane protein YP_126459.1 membrane protein YP_126462.1 Similar to transposase YP_126463.1 Similar to transposase YP_126464.1 Some similarity with eukaryotic protein YP_126469.1 Similar to hypothetical protein YP_126470.1 regulatory protein (GGDEF and EAL domains) YP_126471.1 similar to other proteins YP_126472.1 similar to chitinase YP_126473.1 Similar to B. subtilis PaiA transcriptional repressor of sporulation YP_126474.1 similar to D-alanyl-D-alanine carboxypeptidase YP_126475.1 PilD-dependent secreted protein, tartrate-sensitive acid phosphatase YP_126478.1 similar to membrane-bound lytic murein transglycosylase YP_126479.1 Similar to amino acid ABC transporter (amino acid binding protein) YP_126481.1 Similar to amino acid ABC transporter YP_126482.1 Some similarity with eukarytic proteins YP_126483.1 Similar to glutathione-regulated potassium-efflux system protein kefC (K(+)/H(+) antiporter) YP_126484.1 Similar to long-chain acyl-CoA synthetase YP_126485.1 Similar to guanine deaminase YP_126488.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_126489.1 Similar to transposase, IS630 family YP_126491.1 Similar to 2-nitropropane dioxygenase YP_126492.1 Similar to transcriptional regulator, (TetR family?) YP_126493.1 Similar to hypothetical protein YP_126496.1 Similar to spermidine/putrescine-binding periplasmic protein precursor potD (SPBP) YP_126497.1 Similar to spermidine/putrescine transport system permease protein potC. integral membrane protein YP_126498.1 Similar to spermidine/putrescine transport system permease protein PotB YP_126499.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_126500.1 Similar to dehydrogenase YP_126503.1 Similar to thermostable carboxypeptidase 1 YP_126504.1 Similar to acetyltransferase YP_126507.1 similar to E. coli Ada protein (O6-methylguanine-DNA methyltransferase) YP_126509.1 Some similarity with eukaryotic proteins YP_126511.1 Similar to amine oxidase YP_126513.1 Similar to eukaryotic pyruvate decarboxylase YP_126514.1 Similar to aminopeptidase YP_126515.1 Similar to L.pneumophila lipase LipB YP_126518.1 similar to drug metabolite transport protein (DMT family) YP_126520.1 Similar to predicted phosphoribosyl transferase YP_126521.1 similar to other proteins YP_126522.1 Similar to permeases of the major facilitator superfamily (MFS) YP_126523.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_126524.1 Weakly similar to uridine kinase YP_126525.1 Some similarity with eukaryotic proteins YP_126526.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_126527.1 regulatory protein (GGDEF and EAL domains) YP_126528.1 Similar to unknown protein YP_126529.1 similar to Pyruvate formate-lyase activating enzyme YP_126531.1 Similar to conserved hypothetical protein, similar to C-terminal part of EnhC protein YP_126532.1 Similar to Pseudomonas sensor protein PilS (member of the 2 component response regulator PilS/PilR involved in the regulation of the expression of the type 4 fimbriae) YP_126533.1 Similar to type 4 fimbriae expression regulatory protein PilR (two-component response regulator) YP_126535.1 similar to hydrolase YP_126536.1 similar to protease YP_126538.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_126541.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_126542.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_126545.1 Similar to competence lipoprotein comL precursor YP_126546.1 Required for efficient pilin antigenic variation YP_126547.1 Similar to low affinity potassium transport system protein Kup YP_126549.1 Similar to unknown protein YP_126550.1 Similar to N-acetyl-beta-glucosaminidase YP_126551.1 similar to unknown proteins YP_126552.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_126553.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_126555.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_126556.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_126558.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_126559.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_126560.1 Weakly similar to E. coli Trp operon repressor YP_126563.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_126564.1 Similar to cold shock proteins YP_126565.1 similar to unknown protein YP_126566.1 Similar to conserved hypothetical protein YP_126567.1 Similar to transcriptional regulator, MarR family YP_126568.1 Similar to conserved hypothetical protein YP_126569.1 Similar to acetyltransferase YP_126570.1 similar to amino acid (threonine) efflux protein YP_126571.1 Similar to transcriptional regulator, MarR family YP_126572.1 Similar to conserved hypothetical protein YP_126573.1 similar to unknown protein YP_126574.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_126575.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_126576.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_126577.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_126578.1 the hook connects flagellar basal body to the flagellar filament YP_126579.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_126580.1 makes up the distal portion of the flagellar basal body rod YP_126581.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_126582.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_126583.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_126584.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_126585.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_126588.1 Similar to conserved hypothetical protein YP_126589.1 similar to transport protein YP_126590.1 Similar to electron transfer flavoprotein-ubiquinone oxidoreductase YP_126591.1 Similar to multidrug resistance ABC transporter ATP-binding protein YP_126592.1 Similar to conserved hypothetical protein YP_126594.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_126596.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_126599.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_126600.1 Similar to conserved hypothetical protein YP_126601.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_126602.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_126604.1 similar to sensor histidine kinase YP_126605.1 similar to two component response regulator YP_126606.1 Involved in cell division; probably involved in intracellular septation YP_126607.1 Similar to membrane bound lytic murein transglycosylase YP_126609.1 Similar to conserved hypothetical protein YP_126611.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_126613.1 Similar to conserved hypothetical protein YP_126614.1 Similar to conserved hypothetical protein YP_126615.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_126616.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_126617.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_126618.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_126619.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_126620.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_126621.1 Similar to hypothetical sulfatase YP_126625.1 Similar to oxydoreductase YP_126626.1 Similar to adenylate cyclase YP_126627.1 Similar to drug resistance transporter, MFS superfamily YP_126628.1 Similar to multidrug resistance efflux pump protein YP_126629.1 similar to FrgA (Iron- and Fur- regulated gene), iron repressed gene; promotes intracellular infection; similar to aerobactin synthetases YP_126630.1 similar to unknown protein YP_126632.1 Some similarities with eukaryotic protein YP_126635.1 Similar to conserved hypothetical protein YP_126637.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_126638.1 Similar to major facilitator superfamily (MFS) transporter YP_126639.1 Similar to enhanced entry protein EnhA YP_126640.1 Similar to flagellar protein FliS YP_126641.1 Similar to flagellar hook-associated protein 2 (flagellar capping protein) YP_126643.1 structural flagella protein YP_126644.1 Similar to acetyl-CoA carboxylase beta subunit YP_126645.1 Similar to dihydrofolate:folylpolyglutamate synthetase FolC YP_126646.1 Similar to conserved hypothetical protein YP_126647.1 Similar to colicin V production protein DedE YP_126648.1 Similar to nicotinate-nucleotide adenylyltransferase NadD YP_126649.1 Similar to DNA polymerase III, delta subunit HolA YP_126650.1 Similar to rare lipoprotein B RlpB YP_126651.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_126652.1 Similar to apolipoprotein N-acyltransferase (ALP N-acyltransferase) (copper homeostasis protein CutE) YP_126653.1 Similar to dehydrogenase YP_126654.1 Similar to aldehyde dehydrogenase YP_126655.1 Similar to 3-hydroxyacyl-CoA dehydrogenase YP_126656.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_126657.1 similar to unknown protein YP_126658.1 regulatory protein (GGDEF and EAL domains) YP_126666.1 Similar to conserved hypothetical protein YP_126667.1 Similar to conserved hypothetical protein YP_126668.1 Similar to 1-aminocyclopropane-1-carboxylate deaminase YP_126670.1 molecular chaperone YP_126671.1 Similar to DNA-binding protein Fis YP_126672.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_126673.1 Similar to oxidoreductase YP_126674.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_126677.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_126678.1 Similar to conserved hypothetical protein YP_126679.1 Similar to proton/peptide symporter family protein YP_126680.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_126681.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_126682.1 Similar to aldehyde dehydrogenase YP_126683.1 Similar to short chain dehydrogenase YP_126684.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_126685.1 Similar to DNA polymerase III, epsilon chain YP_126687.1 Some similarity with EnhA protein YP_126689.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_126690.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_126692.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_126693.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_126697.1 carries the fatty acid chain in fatty acid biosynthesis YP_126699.1 Similar to conserved hypothetical protein YP_126700.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_126701.1 Similar to DNA polymerase III, delta' subunit YP_126702.1 Similar to type 4 fimbrial biogenesis protein PilZ YP_126703.1 Similar to deoxyribonuclease belonging to the TatD DNAse family YP_126704.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_126705.1 Similar to major facilitator membrane proteins YP_126706.1 similar to multidrug translocase YP_126707.1 Similar to dolichol-phosphate mannosyltransferase YP_126708.1 similar to glycosyl transferase YP_126709.1 similar to choline kinase YP_126710.1 Similar to conserved hypothetical proteins YP_126711.1 similar to unknown protein YP_126712.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_126713.1 Similar to thioredoxin proteins YP_126714.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_126717.1 Similar to purine nucleoside phosphorylase proteins YP_126719.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_126720.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_126722.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_126723.1 Similar to conserved hypothetical protein YP_126724.1 similar to unknown protein YP_126725.1 similar to polysaccharide biosynthesis protein YP_126726.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_126728.1 Similar to short-chain dehydrogenase YP_126731.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_126732.1 similar to outer membrane proteins YP_126733.2 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_126735.1 similar to acylaminoacyl-peptidase proteins YP_126736.1 similar to conserved hypothetical proteins YP_126738.1 similar to permease of the major facilitator superfamily YP_126739.1 similar to unknown protein YP_126740.1 similar to acetyltransferase, GNAT family YP_126741.1 similar to hypothetical proteins YP_126743.1 Similar to unknown protein YP_126744.1 copper efflux ATPase YP_126746.1 similar to unknown protein YP_126747.1 similar to conserved hypothetical proteins YP_126750.1 Similar to transcriptional regulator (MarR family) YP_126751.1 similar to Cell division protein FtsI/penicillin-binding protein 2 YP_126752.1 Similar to class-D beta-lactamase YP_126753.1 Weakly similar to cytochrome C family proteins YP_126754.1 similar to ATPase components of ABC transporters with duplicated ATPase domains YP_126755.1 similar to multidrug resistance ABC transporter ATP-binding protein YP_126756.1 similar to hypothetical proteins YP_126757.1 Similar to acetyltransferase, GNAT family YP_126758.1 similar to transcription regulator (MerR family) YP_126759.1 Similar to transposase, IS630 family YP_126760.1 Similar to transcription regulators (MerR Family) YP_126761.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_126762.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_126763.1 Similar to major facilitator family (MFS) transporter YP_126764.1 Similar to conserved hypothetical protein YP_126765.1 similar to phosphoenolpyruvate carboxylase YP_126766.1 similar to methyltransferase YP_126767.1 Similar to hypothetical proteins YP_126768.1 similar to hypothetical proteins YP_126770.1 Some similarity with eukaryotic proteins YP_126771.1 Similar to transposase YP_126774.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_126775.1 similar to alpha subunit of fatty-acid oxidation complex, 3-hydroxyacyl-CoA dehydrogenase YP_126776.1 similar to unknown protein, possibly truncated YP_126778.1 similar to carbon storage regulator YP_126779.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_126780.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_126781.1 similar to unknown protein YP_126782.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_126783.1 some similarity with Legionella 33 kDa polypeptide YP_126784.1 similar to unknown protein YP_126787.1 similar to phosphatidylcholine synthase YP_126788.1 similar to aldehyde dehydrogenase YP_126789.1 similar to unknown proteins YP_126790.1 weakly similar to NADP-specific glutamate dehydrogenase YP_126791.1 some similarities to cytochrome B561 YP_126792.1 some similarities to aminomethyltransferases YP_126793.1 Conserved hypothetical protein YP_126795.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_126797.1 Similar to TolQ, involved in the tonB-independent uptake of proteins YP_126798.1 Similar to TolR proteins YP_126799.1 weakly similar to TolA protein YP_126801.1 some similarities to 3'-nucleotidase/nuclease YP_126802.1 similar to molybdopterin biosynthesis protein YP_126803.1 similar to phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase YP_126804.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_126805.1 Similar to thiamine biosynthesis protein ThiS YP_126806.1 similar to C.burnetii thiamine biosynthesis oxidoreductase ThiO YP_126807.1 similar to eukaryotic thiamine biosynthesis protein NMT-1 YP_126810.1 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component YP_126811.1 transmembrane protein YP_126812.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA YP_126813.1 similar to pyruvate dehydrogenase E1 (beta subunit) YP_126814.1 similar to pyruvate dehydrogenase, (E1 alpha subunit) YP_126815.1 similar to para-aminobenzoate synthase, component I YP_126816.1 similar to unknown protein YP_126817.1 Similar to arginine 3rd transport system periplasmic binding protein YP_126818.1 Highly similar to acyl-CoA synthetase, long-chain-fatty-acid--CoA ligase YP_126819.1 similar to cell division inhibitor MinC (septum placement) YP_126820.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_126822.1 conserved hypothetical protein YP_126824.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_126825.1 similar to conserved hypothetical protein YP_126826.1 similar to fimbrial biogenesis and twitching motility protein (type 4) YP_126828.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_126829.1 similar to conserved hypothetical protein YP_126830.1 Conserved hypothetical protein YP_126831.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_126832.1 similar to universal stress protein A UspA YP_126833.1 Similar to 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_126835.1 similar to transport proteins YP_126836.1 similar to conserved hypothetical protein YP_126837.1 Similar to rubredoxin protein YP_126838.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_126839.1 similar to peptide transport proteins YP_126840.1 Similar to unknown protein YP_126841.1 similar to unknown protein YP_126843.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_126844.1 similar to conserved hypothetical protein YP_126847.1 cAMP/cGMP binding protein YP_126851.1 Similar to conserved hypothetical protein YP_126852.1 Similar to hypothetical protein YP_126853.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_126854.1 regulatory protein (GGDEF and EAL domains) YP_126855.1 member of a type I secretion system YP_126856.1 member of a type I secretion system YP_126857.1 member of a type I secretion system YP_126858.1 member of a type I secretion system YP_126859.1 member of a type I secretion system YP_126860.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism YP_126861.1 Similar to conserved hypothetical protein YP_126862.1 Similar to D-alanine aminotransferase YP_126863.1 Similar to penicillin-binding protein precursor (D-alanyl-D-alaninecarboxypeptidase fraction C) YP_126864.1 Similar to rare lipoprotein A RlpA YP_126865.1 Similar to sodium/hydrogen antiporter family protein YP_126866.1 membrane protein YP_126867.1 Cystein rich protein YP_126868.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_126871.1 Similar to acetyltransferase YP_126872.1 Similar to oxidoreductase YP_126875.1 Similar to aminopeptidase N YP_126876.1 Some similarities with sidE protein YP_126880.1 Similar to hypothetical protein YP_126883.1 Weakly similar to mitomycin resistance protein YP_126884.1 similar to adenylate cyclase, family 3 YP_126887.1 Similar to acetyltransferase, GNAT family YP_126888.1 Similar to transcriptional regulator (Lrp family) YP_126889.1 similar to unknown protein YP_126890.1 weak similarity to myosin YP_126891.1 similar to eukaryotic serine threonin protein kinase YP_126894.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_126895.1 Similar to potassium efflux system kefA YP_126896.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_126897.1 Similar to conserved hypothetical protein YP_126898.1 Similar to conserved hypothetical protein YP_126904.1 similar to serine-type D-Ala-D-Ala carboxypeptidase YP_126905.1 regulatory protein (EAL domain) YP_126907.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_126908.1 similar to conserved hypothetical protein YP_126911.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_126912.1 Similar to tRNA-dihydrouridine synthase A DusA YP_126914.1 similar to unknown protein YP_126915.1 Similar to aminotransferase YP_126916.1 Similar to conserved hypothetical protein YP_126918.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_126919.1 Similar to Legionella pneumophila phospholipase C YP_126921.1 Similar to transposase YP_126922.1 Similar to transposase YP_126923.1 Similar to other proteins YP_126925.1 Similar to tranposase YP_126927.1 Similar to hypothetical protein YP_126928.1 Weakly similar to stability protein StbE YP_126929.1 Similar to probable multidrug efflux protein YP_126931.1 Similar to hydrolases YP_126932.1 similar to unknown protein YP_126933.1 Similar to ribosomal large subunit pseudouridine synthase B (Pseudouridylate synthase) YP_126934.1 similar to segregation and condensation protein B YP_126935.1 similar to segregation and condensation protein A YP_126936.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_126937.1 Similar to translation factor YP_126938.1 similar to TrpH protein YP_126939.1 similar to phosphate starvation-inducible protein PhoH YP_126940.1 similar to conserved hypothetical protein YP_126941.1 Similar to magnesium and cobalt efflux protein CorC YP_126945.1 Similar to cytidine/deoxycytidine deaminase Cdd YP_126946.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_126947.1 Similar to 2-deoxyribose-5-phosphate aldolase YP_126948.1 Similar to oxidase YP_126950.1 similar to conserved hypothetical proteins YP_126951.1 similar to Cytochrome B561 YP_126952.1 similar to conserved hypothetical proteins YP_126953.1 secreted protein YP_126954.1 similar to myo-inositol catabolism protein iolE YP_126955.1 similar to malonic semialdehyde oxidative decarboxylase YP_126956.1 Bifuncional protein similar to IolC (sugar kinase) and IolB YP_126957.1 similar to myo-inositol 2-dehydrogenase YP_126958.1 similar to sugar-proton symporter YP_126959.1 similar to metalloprotease YP_126960.1 similar to hyothetical proteins YP_126961.1 similar to dimethylarginine dimethylaminohydrolase YP_126962.1 similar to amino acid transporter YP_126963.1 similar to hypothetical proteins YP_126965.1 similar to conserved hypothetical proteins YP_126966.1 Similar to transport proteins, MFS family YP_126969.1 similar to membrane proteins YP_126978.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_126979.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_126981.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_126983.1 similar to hypothetical proteins YP_126985.1 similar to thiol:disulfide interchange protein YP_126987.1 similar to oxidoreductase, short-chain dehydrogenase/reductase family YP_126990.1 some similarity with flagellar hook-length control protein FliK YP_126992.1 Catalyzes the conversion of citrate to isocitrate YP_126993.1 similar to amino acid antiporter YP_126994.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_126995.1 conserved hypothetical protein YP_126996.1 similar to activator of osmoprotectant transporter ProP (N-terminal part) YP_126997.1 Involved in ubiquinone biosynthesis YP_126998.1 similar to Uracil-DNA glycosylase YP_127001.1 similar to error-prone repair protein YP_127002.1 similar to error-prone repair: SOS-response transcriptional repressors (LexA homologs, RecA-mediated autopeptidases) YP_127003.1 similar to carboxypeptidase G2 and to acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase YP_127005.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_127006.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_127007.1 similar to unknown proteins YP_127008.1 Weakly similar to cytochrome c5 YP_127009.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_127010.1 Catalyzes the phosphorylation of UMP to UDP YP_127011.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_127012.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_127013.1 16 kD immunogenic protein YP_127020.1 Ankyrin repeat protein YP_127021.1 ankyrin repeat protein YP_127022.1 similar to methionine aminopeptidase, type I YP_127023.1 similar to PII uridylyl-transferase YP_127024.1 similar to hypothetical proteins YP_127025.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_127026.1 similar to IMP dehydrogenase/GMP reductase YP_127028.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_127029.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_127030.1 similar to hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_127031.1 similar to hypothetical proteins YP_127032.1 similar to sn-glycerol-3-phosphate transport ATP-binding protein YP_127033.1 similar to glycerol-3-phosphate ABC transporter, permease component YP_127034.1 similar to glycerol-3-phosphate ABC transporter, permease components YP_127035.1 similar to quinone oxidoreductase (NADPH:quinone reductase) YP_127036.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_127037.1 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II YP_127039.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_127040.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_127042.1 similar to Adenylate cyclase 1(ATP pyrophosphate-lyase 1; Adenylylcyclase 1) YP_127045.1 similar to DNA-binding protein fis YP_127046.1 similar to HesB/YadR/YfhF family proteins YP_127047.1 similar to iron-sulpher cluster proteins NifU YP_127048.1 similar cysteine desulfurase YP_127049.1 similar to tRNA/rRNA methyltransferase YP_127050.1 similar to inositol-1-monophosphatase YP_127051.1 similar to signal peptide peptidases YP_127055.1 similar to UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase YP_127056.1 hypothetical gene YP_127057.1 similar to unknown protein YP_127062.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_127064.1 similar to two-component response regulator YP_127065.1 similar to sensor histidine kinase YP_127066.1 conserved hypothetical protein YP_127067.1 similar to periplasmic chaperone LolA YP_127068.1 similar to cell division protein FtsK YP_127070.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_127071.1 similar to rhodanese domain protein YP_127072.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_127074.1 Similar to conserved hypothetical protein YP_127076.1 Catalyzes the rate-limiting step in dNTP synthesis YP_127077.1 Catalyzes the rate-limiting step in dNTP synthesis YP_127079.1 Highly similar to lysyl-tRNA synthetase YP_127080.1 Highly similar to peptide chain release factor 2 YP_127081.1 similar to hypothetical poteins YP_127082.1 Homologous to MotB. These organism have both MotB and MotD. With MotC (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. Either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility YP_127083.1 homologous to MotA; this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; these organisms have both MotA and MotC YP_127084.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_127085.1 similar to flagellar synthesis regulator YP_127086.1 positive regulator of class III flagellar genes YP_127087.1 membrane protein involved in the flagellar export apparatus YP_127088.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_127091.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_127096.1 similar to oxidoreductase YP_127097.1 similar to hypothetical oxidoreductase YP_127098.1 similar to transcriptional regulator (LysR family) YP_127101.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_127102.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_127103.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_127105.1 similar to hypothetical proteins YP_127106.1 Unknown YP_127107.1 This protein performs the mismatch recognition step during the DNA repair process YP_127108.1 similar to hypothetical proteins YP_127109.1 similar to hypothetical proteins YP_127110.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_127112.1 Similar to long-chain fatty acid transport protein YP_127113.1 catalyzes the 4-phospho-L-aspartate from L-aspartate and the formation of lysine from meso-2,6-diaminoheptanedioate YP_127114.1 Similar to UvrD/REP helicase family protein YP_127115.1 similar to unknown protein YP_127116.1 Similar to conserved hypothetical protein YP_127118.1 Similar to major facilitator family transporter YP_127120.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_127123.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_127124.1 Predicted transmembrane protein YP_127125.1 Similar to conserved hypothetical protein YP_127126.1 Similar to acyl-CoA dehydrogenase YP_127127.1 Similar to acetyl-CoA acetyltransferase YP_127128.1 hypothetical gene YP_127129.1 similar to Acetyl/propionyl-CoA carboxylase, beta subunit YP_127130.1 similar to enoyl-CoA hydratase/isomerase YP_127131.1 similar to Acetyl/propionyl-CoA carboxylase, alpha subunit YP_127132.1 Similar to hydroxymethylglutaryl-CoA lyase YP_127133.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase YP_127134.1 similar to unknown proteins YP_127135.1 part of the metNIQ transport system for methionine YP_127136.1 Similar to ABC transporter permease protein YP_127137.1 29 kDa immunogenic protein YP_127138.1 Some similarity with eukaryotic protein YP_127140.1 Similar to conserved hypothetical protein YP_127141.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_127143.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_127144.1 Similar to outer membrane protein YP_127145.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_127146.1 similar to proline iminopeptidase YP_127147.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_127148.1 conserved lipoprotein YP_127149.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_127150.1 similar to unknown proteins YP_127151.1 hypothetical gene YP_127152.1 membrane protein, similar to permease of the drug/metabolite transporter (DMT) superfamily YP_127154.1 hypothetical protein (rhodanese domain) YP_127156.1 similar to alkaline phosphatase YP_127157.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_127158.1 similar to Enoyl-[acyl-carrier-protein] reductase YP_127159.1 similar to peptidyl-prolyl cis-trans isomerase D YP_127160.1 similar to DNA-binding protein HU-beta YP_127161.1 similar to ATP-dependent protease La YP_127162.1 binds and unfolds substrates as part of the ClpXP protease YP_127163.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_127164.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_127166.1 Unknown YP_127167.1 Similar to site specific recombinase, phage integrase family YP_127168.1 Similar to ABC transporter, ATP-binding protein YP_127169.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_127170.1 similar to unknown protein YP_127172.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_127173.1 similar to membrane-bound lytic murein transglycosylase B precursor YP_127174.1 similar to general secretion pathway protein L YP_127175.1 Similar to general secretion pathway protein YP_127176.1 similar to unknown protein YP_127177.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_127178.1 some similarity with eukaryotic proteins YP_127179.1 Similar to alpha,alpha-trehalase YP_127181.1 Similar to lactoylglutathione lyase YP_127182.1 membrane protein YP_127183.1 Some similarity with eukaryotic proteins YP_127186.1 catalyzes the hydrolysis of acylphosphate YP_127187.1 Q-rich protein YP_127189.1 Similar to esterase/lipase YP_127191.1 Similar to hypothetical protein YP_127192.1 signal peptide predicted YP_127193.1 Similar to major facilitator family transporter (MFS) YP_127194.1 similar to chloride channel protein YP_127196.1 Similar to hypothetical protein YP_127198.1 Similar to hypothetical protein YP_127199.1 Similar to glutathione-regulated potassium-efflux system protein KefC (K(+)/H(+)antiporter) YP_127200.1 Similar to MoxR-like ATPases, regulator YP_127201.1 Similar to conserved hypothetical protein YP_127202.1 Similar to unknown protein YP_127203.1 similar to conserved hypothetical protein YP_127205.1 similar to hypothetical protein YP_127206.1 similar to hypothetical transporter YP_127207.1 similar to eukaryotic ectonucleoside triphosphate diphosphohydrolase (apyrase) YP_127208.1 Similar to conserved hypothetical protein YP_127212.1 Similar to D-alanyl-D-alanine carboxypeptidase YP_127213.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_127215.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_127216.1 similar to type IV pilin PilA YP_127217.1 similar to type IV pilin PilA YP_127218.1 Similar to BolA protein YP_127219.1 Similar to amino acid antiporter YP_127220.1 weakly similar to endoglucanase YP_127221.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_127222.1 Similar to hypothetical protein YP_127223.1 Similar to conserved hypothetical protein YP_127224.1 Similar to ATP-dependent DNA helicase YP_127225.1 Similar to ferredoxin YP_127228.1 Similar to conserved hypothetical protein YP_127229.1 Similar to conserved hypothetical protein YP_127230.1 Similar to conserved hypothetical protein YP_127231.1 Similar to transposase YP_127232.1 carbonic anhydrase YP_127236.1 Some similarity with hypothetical protein YP_127242.1 similar to transcription regulators YP_127243.1 similar to methyl transferase YP_127244.1 Similar to conserved hypothetical protein YP_127245.1 Similar to capsular polysaccharide biosynthesis protein YP_127246.1 Similar to N-terminal part of polyketide synthase YP_127247.1 similar to peptide antibiotic synthetase YP_127248.1 similar to acyl-coA dehydrogenase YP_127249.1 similar to 3-hydroxybutyryl-CoA dehydrogenase YP_127250.1 Similar to hypothetical protein YP_127251.1 Similar to conserved hypothetical protein YP_127252.1 Some similarity with eukaryotic proteins YP_127253.1 similar to 3',5'-cyclic-nucleotide phosphodiesterase precursor (CpdP) YP_127256.1 Weakly similar to sphingosine kinase YP_127257.1 Similar to predicted phosphohydrolases YP_127260.1 similar to other protein YP_127261.1 similar to chloromuconate cycloisomerase YP_127262.1 Weakly similar to transcriptional regulator YP_127267.1 Some similarity with eukaryotic proteins YP_127269.1 Similar to transposase YP_127272.1 similar to peptidyl-prolyl cis-trans isomerase proteins YP_127274.1 Similar to transcriptional regulator, TetR family YP_127276.1 hypothetical gene YP_127278.1 Similar to major outer membrane protein momp YP_127279.1 Similar to capsular polysaccharide biosynthesis protein YP_127280.1 Similar to transcriptional regulator YP_127281.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_127282.1 Similar to siderophore biosynthesis protein IucD YP_127283.1 Some similarity with hypothetical protein YP_127284.1 Similar to glutathione S-transferase YP_127285.1 Similar to organic hydroperoxide resistance protein YP_127289.1 Some similarity with eukaryotic proteins. Pattern of chromosome condensation regulator conserved. YP_127290.1 Similar to intracellular protease/amidase YP_127293.1 Some similarity with eukaryotic proteins YP_127295.1 Similar to hydantoin-racemase YP_127296.1 Similar to guanine deaminase YP_127298.1 Similar to phosphohistidine phosphatase SixA YP_127299.1 Similar to conserved hypothetical protein YP_127300.1 membrane protein YP_127301.1 Similar to transposase, IS630 family YP_127302.1 Some similarity with eukaryotic proteins YP_127303.1 predicted membrane protein YP_127305.1 Similar to polysaccharide deacetylase-related protein YP_127306.1 Similar to membrane-bound lytic murein transglycosylase YP_127310.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_127311.1 similar to pterin-4-alpha-carbinolamine dehydratase phhB YP_127312.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_127313.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_127314.1 Similar to preprotein translocase YP_127316.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_127317.1 membrane protein YP_127318.1 similar to ABC transporter ATP-binding protein YP_127319.1 Similar to conserved hypothetical protein YP_127320.1 Similar to endoribonuclease L-PSP YP_127323.1 Essential for recycling GMP and indirectly, cGMP YP_127324.1 Similar to conserved hypothetical protein YP_127325.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_127326.1 Similar to twitching motility protein PilT YP_127327.1 Similar to conserved hypothetical protein YP_127328.1 similar to pyrroline-5-carboxylate reductase YP_127329.1 Predicted integral membrane protein YP_127331.1 Similar to conserved hypothetical protein YP_127332.1 Similar to serine protease YP_127333.1 Similar to transcriptional regulator, AraC family YP_127334.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_127335.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_127336.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_127337.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_127338.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_127339.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_127340.1 Similar to 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase YP_127341.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_127342.1 Similar to dihydroneopterin aldolase YP_127343.1 Similar to cell division protein YP_127344.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_127345.1 Similar to transport protein YP_127346.1 catalyzes branch migration in Holliday junction intermediates YP_127348.1 Similar to cation-efflux family protein YP_127349.1 Similar to transporters YP_127350.1 Similar to septum formation protein Maf YP_127351.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_127352.1 Similar to cell division protein ftsB homolog YP_127353.1 Similar to mevalonate kinase YP_127354.1 Similar to diphosphomevalonate decarboxylase YP_127355.1 Similar to organic radical activating enzymes YP_127356.1 Similar to conserved hypothetical protein YP_127358.1 Similar to conserved hypothetical protein YP_127359.1 Similar to ABC-type transport system involved in resistance to organic solvents YP_127360.1 Similar to ABC transporter ATP-binding protein YP_127361.1 Similar to ABC transporter permease protein YP_127365.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_127366.1 Similar to 3-hydroxy-3-methylglutaryl-coenzyme A reductase YP_127367.1 Weakly similar to mevalonate kinase YP_127368.1 Similar to transposase YP_127369.1 Similar to transposase YP_127370.1 Similar to threonine dehydrogenase YP_127371.1 Similar to conserved hypothetical protein YP_127372.1 Similar to DNA-3-methyladenine glycosylase II YP_127375.1 Similar to cold shock protein YP_127376.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_127377.1 Similar to cation efflux protein YP_127384.1 Ankyrin repeat protein YP_127386.1 Similar to transcriptional regulator, LysR family YP_127387.1 Ankyrin repeat protein YP_127389.1 cAMP/cGMP binding protein YP_127390.1 Similar to potassium uptake protein YP_127391.1 ankyrin repeat protein YP_127393.1 Similar to conserved hypothetical proteins YP_127394.1 ankyrin repeat protein YP_127396.1 Some similarities with eukaryotic proteins YP_127397.1 regulatory protein (GGDEF domain) YP_127402.1 Similar to protein kinase YP_127403.1 Similar to transcriptional regulator, LysR family YP_127404.1 similar to pyridoxamine 5'-phosphate oxidase YP_127405.1 similar to unknown proteins YP_127406.1 Similar to 3-oxoacyl-[acyl-carrier protein] reductase YP_127408.1 Protein with ankyrin repeat and a F-box domain YP_127409.1 Similar to two-component response regulator YP_127414.1 Similar to aminoglycoside 6-adenylyltransferase YP_127415.1 Similar to multidrug resistance ABC transporter ATP-binding protein YP_127417.1 similar to L. pneumophila SdeA protein YP_127421.1 Similar to methyltransferase YP_127422.1 similar to (hydroxyindole) O-methyltransferase YP_127424.1 similar to conserved hypothetical protein YP_127429.1 similar to transcriptional regulator, deoR family YP_127430.1 Similar to acetyltransferases YP_127431.1 similar to conserved hypothetical protein YP_127432.1 predicted membrane protein YP_127433.1 Weakly similar to transcriptional regulator, LuxR family YP_127436.1 Similar to hypothetical hydrolase proteins YP_127437.1 Similar to eukaryotic sphingosine-1-phosphate lyase 1 YP_127438.1 Similar to multidrug efflux RND membrane fusion protein MexE YP_127439.1 Similar to RND multidrug efflux transporter YP_127440.1 contains an HPT Histidine-containing phosphotransfer (HPt) domain YP_127441.1 Similar to polyketide synthase of type I YP_127442.1 Similar to two component sensor histidine kinase YP_127443.1 Similar to response regulator YP_127444.1 Similar to eukaryotic SAM dependent methyltransferase YP_127445.1 Similar to conserved hypothetical protein YP_127446.1 similar to polyketide synthase of type I YP_127448.1 Similar to transport proteins YP_127449.1 Some similarity with eukaryotic proteins YP_127450.1 Present a domain similar to IcmL prtein YP_127452.1 Similar to sulfate transporters YP_127453.1 Similar to carbonic anhydrase proteins YP_127454.1 hypothetical gene YP_127455.1 similar to ornithine cyclodeaminase YP_127456.1 Similar to ketosteroid isomerase homolog YP_127457.1 Similar to transporters YP_127460.1 similar to unknown proteins YP_127461.1 similar to unknown protein YP_127462.1 Similar to conserved hypothetical protein YP_127463.1 Periplamic protein weakly similar to AlgJ YP_127464.1 Similar to alginate o-acetyltransferase AlgI YP_127465.1 Predicted integral membrane protein YP_127467.1 similar to unknown protein YP_127468.1 Similar to oxidoreductase YP_127469.1 similar to conserved hypothetical protein YP_127471.1 similar to conserved hypothetical protein YP_127473.1 Similar to hemin binding protein Hbp YP_127474.1 Similar to hypothetical sugar nucleotide epimerase YP_127476.1 Some similarity with eukaryotic protein YP_127477.1 similar to chitinase YP_127478.1 Similar to choline monooxygenase YP_127479.1 similar to unknown proteins YP_127482.1 similar to unknown protein YP_127483.1 Similar to major outer membrane protein YP_127485.1 similar to other proteins YP_127486.1 similar to acyl-CoA dehydrogenase YP_127487.1 similar to propionyl-CoA carboxylase beta chain YP_127488.1 Similar to 3-oxoacyl-[acyl-carrier-protein] synthase III YP_127489.1 Similar to acyl-CoA synthetase YP_127490.1 Similar to acyl-CoA synthetase YP_127491.1 similar to acyl carrier protein (ACP) YP_127492.1 Similar to 3-oxoacyl-[acyl-carrier protein] reductase YP_127493.1 Similar to 3-oxoacyl-(acyl-carrier-protein) synthase III YP_127494.1 Similar to acyl-carrier protein YP_127495.1 Similar to multidrug resistance protein YP_127496.1 similar to sterol desaturase-related protein YP_127497.1 similar to nitric oxide reductase YP_127498.1 similar to multidrug resistance ABC transporter ATP-binding protein YP_127499.1 membrane protein YP_127500.1 Similar to conserved hypothetical protein YP_127501.1 catalyzes the formation of formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine from GTP YP_127502.1 similar to hypothetical protein YP_127503.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_127506.1 Similar to C4-dicarboxylate transport protein YP_127508.1 Similar to hypothetical protein DedA YP_127510.1 Similar to amidotransferase YP_127511.1 similar to alcohol dehydrogenase YP_127512.1 similar to aldehyde dehydrogenase YP_127513.1 Similar to glutamine synthase YP_127514.1 Similar to hypothetical protein YP_127515.1 similar to conserved hypothetical protein YP_127517.1 Similar to metallo-beta-lactamase superfamily proteins YP_127519.1 membrane protein YP_127521.1 Similar to poly(3-hydroxyalkanoate) synthetase YP_127522.1 Catalyses the synthesis of acetylphosphate from acetyl-CoA and inorganic phosphate YP_127524.1 Similar to curved DNA-binding protein (sequence similarity to chaperone protein dnaJ) YP_127525.1 similar to unknown protein YP_127526.1 Similar to acyltransferase YP_127527.1 Similar to conserved hypothetical protein YP_127528.1 Similar to imidazolonepropionase and related amidohydrolases YP_127529.1 membrane protein YP_127530.1 Similar to conserved hypothetical protein YP_127531.1 Similar to conserved hypothetical protein YP_127533.1 membrane protein YP_127534.1 Similar to glycerol-3-phosphate-binding periplasmic protein precursor YP_127535.1 Similar to glycerophosphodiester phosphodiesterase YP_127536.1 Similar to hypothetical protein YP_127537.1 Similar to leucine dehydrogenase YP_127538.1 Similar to O-methyltransferase YP_127540.1 similar to unknown protein YP_127541.1 Similar to glutathione S-transferase (maleylacetoacetate isomerase) YP_127543.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_127545.1 similar to ATP-binding component of ABC transporter YP_127546.1 Similar to ABC transporter, permease component YP_127547.1 Similar to CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_127548.1 Similar to phosphatase YP_127553.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_127554.1 similar to ankyrin repeat domain protein YP_127557.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_127558.1 involved in methylation of ribosomal protein L3 YP_127559.1 similar to conserved hypothetical protein YP_127560.1 similar to conserved hypothetical protein with rhodanese domain YP_127561.1 Similar to glutaredoxin Grx YP_127562.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_127563.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_127564.1 similar to glutamate racemase YP_127567.1 Similar to conserved hypothetical protein YP_127569.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_127571.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_127572.1 Similar to conserved hypothetical protein YP_127573.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_127574.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_127576.1 Similar to serine transporter YP_127577.1 ankyrin repeat protein YP_127578.1 similar to type II secretion system protein-like protein and twitching mobility protein YP_127580.1 Similar to hypothetical protein YP_127581.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_127583.1 Unknown, N-terminal similar to Legionella 33 kDa polypeptide YP_127584.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_127585.1 Similar to geranyltranstransferase; farnesyl-diphosphate synthase YP_127586.1 Similar to biotin synthesis protein YP_127587.1 Similar to competence protein ComF YP_127588.1 Similar to membrane-associated metalloprotease proteins YP_127591.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_127592.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_127593.1 Similar to methyltransferase hemK YP_127594.1 Similar to DnaK suppressor protein YP_127597.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_127602.1 Similar to ATP-dependent RNA helicase deaD (cold-shock DEAD-box protein A) YP_127603.1 Similar to conserved hypothetical protein YP_127604.1 Similar to 2,4-dienoyl-CoA reductase YP_127606.1 Similar to alkyl hydroperoxide reductase AhpD YP_127607.1 Similar to alkyl hydroperoxide reductase AhpC YP_127609.1 catalyzes the oxidation of malate to oxaloacetate YP_127610.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_127611.1 Similar to oxygen-independent coproporphyrinogen III oxidase YP_127612.1 Similar to amidase YP_127613.1 Predicted membrane protein YP_127614.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_127615.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_127616.1 Similar to conserved hypothetical protein YP_127620.1 Similar to hypothetical protein YP_127621.1 Similar to conserved hypothetical protein YP_127623.1 Similar to transcriptional regulator YP_127624.1 Similar to conserved hypothetical protein YP_127625.1 Similar to conserved hypothetical protein YP_127626.1 Similar to transposase YP_127627.1 Similar to predicted ATPase (AAA+ superfamily) YP_127628.1 Similar to restriction endonuclease YP_127630.1 Some similarity with eukaryotic proteins YP_127633.1 similar to transcriptional regulator, LysR family YP_127634.1 similar to potassium uptake protein Kup YP_127635.1 Some similarity with eukaryotic proteins YP_127636.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_127637.1 Similar to acetoacetyl-CoA reductase YP_127638.1 conserved hypothetical protein, some similarity with stress proteins YP_127639.1 similar to cation transport ATPase YP_127641.1 Similar to universal stress protein YP_127643.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_127644.1 Similar to amino acid transport protein YP_127646.1 Similar to major facilitator family transporter YP_127648.1 Some similarity with eukaryotic proteins YP_127649.1 Similar to bacterioferritin YP_127651.1 Similar to conserved hypothetical protein YP_127652.1 similar to hypothetical peptidases YP_127653.1 Similar to aminoglycoside 6'-N-acetyltransferase YP_127654.1 C-terminal part similar to Legionella unknown virulence protein YP_127655.1 Some similarity with eukaryotic proteins YP_127657.1 Similar to transcriptional regulator, LysR family YP_127658.1 similar to monooxygenase YP_127660.1 Similar to MutT/nudix family protein YP_127662.1 Some similarity with eukaryotic proteins YP_127665.1 regulatory protein (GGDEF domain) YP_127666.1 Similar to conserved hypothetical protein YP_127667.1 Unknown YP_127668.1 Similar to beta-lactamase precursor (Cephalosporinase) YP_127673.1 Similar to beta-lactamase precursor YP_127676.1 Ankyrin repeat protein YP_127677.1 Some similarity with eukaryotic proteins YP_127685.1 Similar to conserved hypothetical protein YP_127687.1 membrane protein YP_127689.1 Similar to florfenicol efflux pump-like protein YP_127690.1 similar to conserved hypothetical protein YP_127691.1 Similar to conserved hypothetical protein YP_127697.1 Similar to D-alanyl-D-alanine dipeptidase YP_127698.1 predicted integral membrane protein YP_127699.1 Similar to N-hydroxyarylamine O-acetyltransferase YP_127700.1 Ankyrin repeat protein YP_127703.1 Similar to unknown protein YP_127705.1 ankyrin repeat protein YP_127706.1 Similar to two-component response regulator YP_127707.1 Similar to two-component sensor histidine kinase YP_127708.1 Similar to guanylate cyclase-related protein YP_127711.1 Similar to hypothetical protein YP_127712.1 Similar to major facilitator family transporters YP_127713.1 Similar to aspartyl/asparaginyl beta-hydroxylase YP_127714.1 Some similarity with Legionella effector protein B YP_127715.1 Similar to SidD protein YP_127716.1 Similar to hydrogenase 1 maturation protease YP_127717.1 Similar to coenzyme F420-reducing hydrogenase, alpha subunit YP_127718.1 Similar to coenzyme F420-reducing hydrogenase, gamma subunit YP_127719.1 Similar to 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases YP_127720.1 Similar to hydrogenase subunit YP_127727.1 weakly similar to high-affinity nickel-transport protein NixA YP_127728.1 similar to glycosyl transferase YP_127729.1 Similar to hypothetical protein YP_127730.1 Similar to conserved hypothetical protein YP_127731.1 Integral membrane protein, similar to metabolite efflux pump YP_127733.1 Similar to hypothetical protein YP_127734.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_127735.1 Protein with TPR motifs (protein-protein interaction motif) YP_127737.1 catalyzes the formation of dUMP from dUTP YP_127738.1 similar to DNA/pantothenate metabolism flavoprotein YP_127740.1 hypothetical gene YP_127742.1 Similar to conserved hypothetical protein YP_127743.1 Similar to alcohol dehydrogenase YP_127744.1 Similar to small heat shock protein YP_127745.1 Similar to conserved hypothetical protein YP_127746.1 Similar to homospermidine synthase YP_127747.1 Similar to rRNA methylase YP_127748.1 Similar to thiamin pyrophosphokinase YP_127749.1 Similar to conserved hypothetical protein YP_127752.1 Similar to conserved hypothetical protein YP_127753.1 similar to carbonic anhydrase YP_127754.1 similar to multidrug resistance protein, MFS superfamily YP_127755.1 Similar to hypothetical protein YP_127758.1 similar to sensor histidine kinase/response regulator YP_127764.1 Similar to multidrug efflux pump YP_127765.1 Similar to efflux protein YP_127766.1 Similar to outer membrane efflux protein YP_127768.1 Major facilitator superfamily (MFS) transporter YP_127769.1 Similar to transcriptional regulator (Lrp family) YP_127774.1 similar to other protein YP_127775.1 Some similarity with transcriptional regulators YP_127778.1 weakly similar to alpha-glucosidase YP_127781.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_127782.1 similar to chorismate mutase (N-terminal part) YP_127783.1 similar to chorismate mutase (C-terminal part) YP_127784.1 Similar to aspartate aminotransferase YP_127785.1 with TehA confers resistance to tellurite YP_127786.1 similar to unknown protein YP_127787.1 similar to hemoglobin (protozoan/cyanobacterial globin family) YP_127788.1 similar to xylene monooxygenase YP_127791.1 Similar to large conductance mechanosensitive channel protein YP_127796.1 similar to membrane-bound lytic murein transglycosylase A YP_127798.1 similar to protein secretion chaperonin CsaA YP_127799.1 Predicted transmembrane protein YP_127800.1 Similar to trancriptional regulator, AraC family YP_127803.1 membrane protein YP_127804.1 Similar to hexose phosphate transport protein YP_127805.1 Similar to N-terminal part of rare lipoprotein A YP_127806.1 Similar to protein kinase YP_127807.1 Some similarity with eukaryotic proteins YP_127808.1 Similar to transposase YP_127810.1 similar to eukaryotic serine threonin protein kinase YP_127811.1 Similar to Legionella transcriptionnal regulator YP_127813.1 Similar to heat shock protein DnaJ YP_127815.1 Similar to phage-related integrase YP_127816.1 Similar to virulence proteins YP_127817.1 Similar to helicase YP_127818.1 Similar to conserved hypothetical protein YP_127819.1 Similar to conserved hypothetical protein YP_127821.1 Similar to Legionella LvrA protein YP_127822.1 Similar to conserved hypothetical protein YP_127823.1 Similar to other protein YP_127825.1 Similar to integrase YP_127826.1 Similar to hypothetical protein YP_127827.1 Similar to conserved hypothetical protein YP_127831.1 Similar to glutaryl-CoA dehydrogenase YP_127832.1 Similar to pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit YP_127833.1 Similar to hypothetical proteins YP_127834.1 similar to FlhB protein, part of export apparatus for flagellar proteins YP_127837.1 Similar to periplasmic dipeptidase for D-ala-D-ala dipeptidase YP_127838.1 weakly similar to cysteine protease YP_127839.1 similar to phospholipase/lecithinase/hemolysin YP_127840.1 similar to Sphingomyelin phosphodiesterase YP_127841.1 similar to D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_127842.1 similar to partition protein ParB YP_127844.1 Predicted integral membrane protein YP_127845.1 similar to rRNA methylase (sun protein) YP_127846.1 similar to methionyl-tRNA formyltransferase YP_127847.1 similar to polypeptide deformylase YP_127848.1 similar to unknown protein YP_127849.1 similar to E. coli Smf protein YP_127850.1 similar to unknown protein YP_127851.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity YP_127852.1 similar to membrane bound acyltransferase YP_127853.1 Similar to conserved hypothetical protein YP_127854.1 Similar to hypothetical protein YP_127856.1 Similar to unknown protein YP_127858.1 Similar to unknown protein YP_127859.1 Similar to peptidase YP_127860.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_127861.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_127864.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_127865.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_127866.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_127868.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_127869.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_127871.1 Similar to cell division protein YP_127872.1 similar to chromosome partition protein smc YP_127873.1 Similar to acid phosphatase, class B YP_127876.1 Weakly similar to cysteine protease YP_127877.1 Similar to hypothtical protein YP_127878.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_127881.1 Similar to conserved hypothetical protein YP_127882.1 Similar to hypothetical protein YP_127883.1 membrane protein YP_127884.1 Predicted membrane protein, similar to permease YP_127885.1 Similar to leucine aminopeptidase YP_127886.1 Similar to DNA polymerase III, chi subunit YP_127887.1 Similar to hypothetical protein YP_127888.1 Similar to aminopeptidase YP_127889.1 similar to integral membrane protein MviN YP_127890.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_127897.1 similar to protein from Stx2 converting bacteriophage I YP_127898.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_127900.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_127901.1 belong to the CinA protein family YP_127902.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_127903.1 involved in the peptidyltransferase reaction during translation YP_127905.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_127906.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_127907.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_127909.1 regulatory protein (GGDEF domain) YP_127910.1 similar to octaprenyl-diphosphate synthase YP_127911.1 hypothetical gene YP_127914.1 similar to predicted ATPase YP_127915.1 similar to unknown protein YP_127916.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_127917.1 similar to pantothenate synthetases YP_127918.1 Similar to conserved hypothetical proteins YP_127919.1 biotin carboxylase; with subunit B, the carboxyltansferase/biotincarboxyl carrier subunit catalyzes the formation of oxaloacetate from pyruvate YP_127920.1 Similar to dienelactone hydrolase family protein YP_127921.1 similar to unknown protein YP_127922.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_127923.1 Similar to cell division ABC transporter, permease protein FtsX YP_127924.1 Highly similar to cell division ABC transporter, ATP-binding protein FtsE YP_127925.1 Similar to C-terminal part of signal recognition particle GTPase, FtsY YP_127926.1 Similar to zinc protease YP_127927.1 Similar to zinc protease YP_127928.1 Similar to methyltransferase proteins YP_127932.1 Similar to 5'-nucleotidase, catalytic domain YP_127933.1 Similar to unknown proteins YP_127934.1 similar to oxidoreductase YP_127935.1 similar to D-alanine-D-alanine ligase (N-terminal part) YP_127936.1 similar to aldolase YP_127937.1 Similar to hypothetical protein YP_127939.1 similar to hypothetical protein YP_127940.1 Similar to small basic protein SbpA YP_127946.1 similar to cation transport ATPase YP_127948.1 Similar to SAM dependent methyltransferase YP_127949.1 Similar to eukaryotic phytanoyl-CoA dioxygenase YP_127950.1 similar to glycosyltransferase YP_127951.1 similar to unknown proteins YP_127952.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_127954.1 similar to N-acetylmuramoyl-L-alanine amidase YP_127955.1 similar to conserved hypothetical protein YP_127956.1 similar to conserved hypothetical protein YP_127957.1 similar to stringent starvation protein B YP_127958.1 similar to stringent starvation protein A YP_127959.1 similar to ubiquinol-cytochrome c oxydoreductase, cytochrome c1 YP_127960.1 Similar to ubiquinol--cytochrome c reductase, cytochrome b YP_127961.1 Similar to ubiquinol--cytochrome c reductase, iron-sulfur subunit YP_127962.1 forms a direct contact with the tRNA during translation YP_127963.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_127964.1 similar to ferredoxin 2fe-2s protein YP_127965.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_127966.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_127967.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_127968.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_127970.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_127971.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_127972.1 Similar to conserved hypothetical protein YP_127975.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_127976.1 cAMP/cGMP binding protein YP_127977.1 Similar to unknown protein YP_127978.1 Some simillarity with eukaryotic proteins YP_127979.1 similar to membrane protein YP_127981.1 Similar to queuine tRNA-ribosyltransferase YP_127982.1 Similar to disulfide bond formation protein DsbB YP_127983.1 Similar to cytochrome c5 YP_127984.1 similar to 2-amino-3-ketobutyrate coenzyme A ligase YP_127985.1 response regulator YP_127986.1 membrane protein YP_127987.1 Similar to signal transduction histidine kinase YP_127988.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_127990.1 Similar to uroporphyrinogen III methylase HemX YP_127992.1 Similar to cation-efflux system membrane protein YP_127993.1 Similar to conserved hypothetical protein YP_127994.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_127995.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_127996.1 Similar to GTPase YP_128000.1 Similar to hypothetical protein YP_128001.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_128002.1 Similar to hypothetical protein YP_128003.1 Similar to unknown protein YP_128005.1 Similar to response regulator YP_128008.1 similar to unknown protein YP_128010.1 Similar to HIT( Histidine triad nucleotide-binding protein) family protein YP_128012.1 Similar to L-sorbosone dehydrogenase YP_128014.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_128015.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_128016.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_128017.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_128018.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_128019.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_128020.1 Catalyzes the transfer of electrons from NADH to quinone YP_128025.1 Catalyzes the transfer of electrons from NADH to quinone YP_128027.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_128030.1 Catalyzes the transfer of electrons from NADH to quinone YP_128032.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_128035.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_128037.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_128041.1 Similar to predicted RNA-binding protein YP_128042.1 Similar to O-acetyltransferase YP_128044.1 Similar to phosphatidylglycerophosphate synthase YP_128045.1 Similar to DnaA, ATPase involved in DNA replication initiation YP_128046.1 Similar to coproporphyrinogen oxidase A YP_128048.1 Predicted membrane protein, similar to transporters YP_128050.1 Similar to conserved hypothetical protein YP_128051.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_128053.1 Similar to conserved hypothetical protein YP_128054.1 Similar to conserved hypothetical protein YP_128055.1 similar to unknown protein YP_128057.1 Similar to aminopeptidase YP_128058.1 membrane protein YP_128060.1 hypothetical gene YP_128061.1 Similar to disulfide bond chaperones of the HSP33 family YP_128062.1 Similar to hypothetical protein YP_128063.1 Similar to conserved hypothetical protein YP_128064.1 Similar to GTP-binding protein TypA/BipA YP_128065.1 catalyzes the phosphorylation of NAD to NADP YP_128067.1 Similar to cold shock protein CspC YP_128069.1 Similar to conserved hypothetical protein YP_128072.1 Similar to acyl-CoA hydrolase YP_128073.1 Similar to transcriptional accessory protein YP_128074.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_128075.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_128076.1 Similar to lysophospholipase A YP_128077.1 Similar to unknown protein YP_128078.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_128079.1 Highly similar to bacterioferritin comigratory protein YP_128080.1 similar to efflux protein YP_128081.1 similar to PhoH protein YP_128082.1 similar to guanosine monophosphate reductase GuaC YP_128083.1 protein with repetitions YP_128084.1 similar to esterase YP_128087.1 Similar to ribonuclease YP_128088.1 similar to unknown proteins YP_128089.1 Similar to cold shock protein YP_128091.1 similar to amidase YP_128092.1 similar to unknown protein YP_128093.1 hypothetical tetratricopeptide repeat protein YP_128094.1 similar to unknown proteins YP_128095.1 similar to unknow protein YP_128096.1 Similar to hypothetical protein YP_128097.1 similar to unknown protein YP_128098.1 Similar to MoxR-like ATPases, regulator YP_128100.1 Similar to tRNA-dihydrouridine synthase B YP_128102.1 Involved in pteridine salvage and antifolate resistance YP_128103.1 Similar to conserved hypothetical protein YP_128104.1 Similar to unknown protein YP_128106.1 similar to unknown protein YP_128108.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_128109.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_128110.1 similar to predicted permeases YP_128112.1 hydrolyzes diadenosine polyphosphate YP_128113.1 Similar to L-asparaginase I YP_128121.1 Similar to electron transport complex protein rnfB YP_128122.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_128123.1 Belongs to the polyprenyl P-hydroxybenzoate / phenylacrylic acid decarboxylases family. YP_128125.1 secreted protein YP_128126.1 Highly similar to transcriptional regulator ExsB YP_128127.1 Highly similar to mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_128129.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_128130.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_128131.1 Highly similar to chromosome partitioning protein ParA family YP_128132.1 similar to chromosome partitioning protein parB YP_128136.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_128139.1 similar to cytochrome c YP_128141.1 similar to ferredoxin component of dioxygenase YP_128142.1 similar to glycosyltransferases YP_128143.1 Similar to transporter, LysE family YP_128144.1 Similar to conserved hypothetical protein YP_128146.1 similar to conserved hypothetical protein YP_128147.1 similar to P.aeruginosa probable ubiquinone biosynthesis protein ubiB YP_128152.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_128153.1 Similar to regulatory protein (GGDEF domains) YP_128155.1 hypothetical gene YP_128158.1 Hypothetical gene YP_128159.1 Similar to transcriptional regulator YP_128160.1 Similar to hypothetical protein YP_128161.1 transposase YP_128162.1 Similar to unknown protein YP_128163.1 Similar to predicted helicase YP_128164.1 Similar to conserved hypothetical protein YP_128165.1 Similar to conserved hypothetical protein YP_128166.1 Similar to conserved hypothetical protein YP_128167.1 Similar to conserved hypothetical protein YP_128168.1 Similar to transposase YP_128170.1 Similar to conserved hypothetical protein YP_128171.1 Highly similar to lytic murein transglycosylase YP_128172.1 Similar to conserved hypothetical protein YP_128173.1 Similar to hypothetical protein YP_128174.1 similar to ABC transporter permease protein YP_128175.1 similar to ATP-binding protein of ABC transporter YP_128176.1 conserved lipoprotein YP_128177.1 Similar to outer membrane efflux protein YP_128178.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_128179.1 similar to unknown protein YP_128180.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_128181.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_128183.1 Similar to Sec-independent protein translocase TatC YP_128184.1 similar to conserved hypothetical protein YP_128186.1 Similar to C-terminal part of NAD(P)H-flavin reductase YP_128187.1 Highly similar to 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases YP_128188.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_128189.1 Highly similar to thioredoxin YP_128190.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_128191.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_128192.1 Similar to hypothetical protein YP_128193.1 Similar to transposase YP_128194.1 Similar to transposase, IS630 family YP_128195.1 similar to lipid A biosynthesis lauroyl acyltransferase YP_128196.1 similar to acyl transferase YP_128197.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_128198.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_128199.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_128201.1 Similar to ADP-heptose:LPS heptosyltransferase II YP_128204.1 Similar to O-acyltransferase YP_128205.1 Highly similar to cystathionine beta-synthase YP_128208.1 Some similarity with eukaryotic proteins YP_128209.1 Highly similar to integration host factor, beta subunit YP_128210.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_128211.1 Similar to protease YP_128212.1 transmembrane protein, similar to hypothetical membrane-bound serine protease YP_128213.1 Conserved hypothetical protein YP_128214.1 Similar to major outer membrane protein precursor YP_128217.1 Similar to sodium-type flagellar protein MotY YP_128218.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_128219.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_128223.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_128224.1 Similar to conserved hypothetical protein YP_128225.1 Similar to glycerophosphoryl diester phosphodiesterase (ATA start codon) YP_128226.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_128227.1 Similar to translation initiation protein YP_128228.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_128231.1 similar to protease YP_128233.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_128234.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_128235.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_128236.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_128237.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_128238.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_128239.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_128240.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_128241.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_128242.1 Similar to ATP synthase subunit i YP_128244.1 Similar to lipoproteins YP_128245.1 similar to lipoproteins YP_128246.1 similar to phosphoheptose isomerase YP_128247.1 conserved hypothetical protein, lipoprotein YP_128248.1 conserved hypothetical protein, methyltransferase YP_128249.1 similar to alkane monooxygenase YP_128250.1 Similar to sulfate permease and related transporters (MFS superfamily) with a C-terminal cAMP binding motif. YP_128251.1 Similar to eukaryotic zinc metalloproteinase YP_128253.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_128254.1 inner membrane protein YP_128255.1 Similar to conserved hypothetical protein YP_128256.1 similar to ribonuclease P protein component (RNase P) YP_128257.1 in Escherichia coli transcription of this gene is enhanced by polyamines