-- dump date 20140619_125434 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_796453.1 116326530 4405781 complement(406..1776) 1 NC_008503.1 lactococcin A ABC transporter permease protein 1776 4405781 LACR_A01 Lactococcus lactis subsp. cremoris SK11 lactococcin A ABC transporter permease protein YP_796453.1 406 R 272622 CDS YP_796454.1 116326531 4405782 complement(1792..3942) 1 NC_008503.1 bacteriocin-processing peptidase 3942 4405782 LACR_A02 Lactococcus lactis subsp. cremoris SK11 bacteriocin-processing peptidase YP_796454.1 1792 R 272622 CDS YP_796455.1 116326532 4405783 4674..5354 1 NC_008503.1 transposase 5354 4405783 LACR_A03 Lactococcus lactis subsp. cremoris SK11 transposase YP_796455.1 4674 D 272622 CDS YP_796456.1 116326533 4405785 complement(5960..6496) 1 NC_008503.1 hypothetical protein 6496 4405785 LACR_A05 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796456.1 5960 R 272622 CDS YP_796457.1 116326534 4405786 complement(6489..7649) 1 NC_008503.1 replication initiator protein 7649 4405786 LACR_A06 Lactococcus lactis subsp. cremoris SK11 replication initiator protein YP_796457.1 6489 R 272622 CDS YP_796458.1 116326535 4405787 8401..9081 1 NC_008503.1 transposase 9081 4405787 LACR_A07 Lactococcus lactis subsp. cremoris SK11 transposase YP_796458.1 8401 D 272622 CDS YP_796459.1 116326536 4405777 9729..10040 1 NC_008503.1 nucleoid DNA-binding protein 10040 4405777 LACR_A08 Lactococcus lactis subsp. cremoris SK11 nucleoid DNA-binding protein YP_796459.1 9729 D 272622 CDS YP_796460.1 116326537 4405778 complement(10270..10512) 1 NC_008503.1 hypothetical protein 10512 4405778 LACR_A09 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796460.1 10270 R 272622 CDS YP_796461.1 116326538 4405779 complement(10600..11490) 1 NC_008503.1 replication initiator protein 11490 4405779 LACR_A10 Lactococcus lactis subsp. cremoris SK11 replication initiator protein YP_796461.1 10600 R 272622 CDS YP_796462.1 116326539 4405780 complement(12694..13662) 1 NC_008503.1 relaxase/mobilization nuclease domain-containing protein 13662 4405780 LACR_A11 Lactococcus lactis subsp. cremoris SK11 relaxase/mobilization nuclease domain-containing protein YP_796462.1 12694 R 272622 CDS YP_796463.1 116326541 4405788 complement(28..717) 1 NC_008504.1 diadenosine tetraphosphatase-like protein 717 4405788 LACR_B1 Lactococcus lactis subsp. cremoris SK11 diadenosine tetraphosphatase-like protein YP_796463.1 28 R 272622 CDS YP_796464.1 116326542 4405789 846..1106 1 NC_008504.1 transposase 1106 4405789 LACR_B2 Lactococcus lactis subsp. cremoris SK11 transposase YP_796464.1 846 D 272622 CDS YP_796465.1 116326543 4405791 4328..4765 1 NC_008504.1 response regulator 4765 4405791 LACR_B4 Lactococcus lactis subsp. cremoris SK11 response regulator YP_796465.1 4328 D 272622 CDS YP_796466.1 116326544 4405793 7100..8257 1 NC_008504.1 replication initiator protein 8257 4405793 LACR_B6 Lactococcus lactis subsp. cremoris SK11 replication initiator protein YP_796466.1 7100 D 272622 CDS YP_796467.1 116326545 4405794 8271..8798 1 NC_008504.1 hypothetical protein 8798 4405794 LACR_B7 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796467.1 8271 D 272622 CDS YP_796468.1 116326546 4405795 8795..9439 1 NC_008504.1 hypothetical protein 9439 4405795 LACR_B8 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796468.1 8795 D 272622 CDS YP_796469.1 116326548 4405854 254..1645 1 NC_008505.1 putative multicopper oxidase 1645 4405854 LACR_C01 Lactococcus lactis subsp. cremoris SK11 putative multicopper oxidase YP_796469.1 254 D 272622 CDS YP_796470.1 116326549 4405855 complement(1917..2621) 1 NC_008505.1 transposase 2621 4405855 LACR_C02 Lactococcus lactis subsp. cremoris SK11 transposase YP_796470.1 1917 R 272622 CDS YP_796471.1 116326550 4405856 complement(2783..3058) 1 NC_008505.1 transposase 3058 4405856 LACR_C03 Lactococcus lactis subsp. cremoris SK11 transposase YP_796471.1 2783 R 272622 CDS YP_796472.1 116326551 4405857 3229..4266 1 NC_008505.1 hypothetical protein 4266 4405857 LACR_C04 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796472.1 3229 D 272622 CDS YP_796473.1 116326552 4405858 4785..5675 1 NC_008505.1 transposase 5675 4405858 LACR_C05 Lactococcus lactis subsp. cremoris SK11 transposase YP_796473.1 4785 D 272622 CDS YP_796474.1 116326553 4405859 6029..6610 1 NC_008505.1 aminodeoxychorismate synthase, glutamine amidotransferase subunit 6610 4405859 LACR_C06 Lactococcus lactis subsp. cremoris SK11 aminodeoxychorismate synthase, glutamine amidotransferase subunit YP_796474.1 6029 D 272622 CDS YP_796475.1 116326554 4405860 6615..8540 1 NC_008505.1 anthranilate/para-aminobenzoate synthase component I 8540 4405860 LACR_C07 Lactococcus lactis subsp. cremoris SK11 anthranilate/para-aminobenzoate synthase component I YP_796475.1 6615 D 272622 CDS YP_796476.1 116326555 4405796 complement(8636..9133) 1 NC_008505.1 acetyltransferase 9133 4405796 LACR_C08 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_796476.1 8636 R 272622 CDS YP_796477.1 116326556 4405797 complement(9313..9777) 1 NC_008505.1 transcription activator effector binding domain-containing protein 9777 4405797 LACR_C09 Lactococcus lactis subsp. cremoris SK11 transcription activator effector binding domain-containing protein YP_796477.1 9313 R 272622 CDS YP_796478.1 116326557 4405798 10270..11511 1 NC_008505.1 major facilitator superfamily permease 11511 4405798 LACR_C10 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_796478.1 10270 D 272622 CDS YP_796479.1 116326558 4405799 complement(11776..12351) 1 NC_008505.1 glycopeptide antibiotics resistance protein 12351 4405799 LACR_C11 Lactococcus lactis subsp. cremoris SK11 glycopeptide antibiotics resistance protein YP_796479.1 11776 R 272622 CDS YP_796480.1 116326559 4405800 complement(12446..13126) 1 NC_008505.1 transposase 13126 4405800 LACR_C12 Lactococcus lactis subsp. cremoris SK11 transposase YP_796480.1 12446 R 272622 CDS YP_796481.1 116326560 4405801 13286..14416 1 NC_008505.1 cell surface protein 14416 4405801 LACR_C13 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_796481.1 13286 D 272622 CDS YP_796482.1 116326561 4405802 14652..15368 1 NC_008505.1 cell surface protein 15368 4405802 LACR_C14 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_796482.1 14652 D 272622 CDS YP_796483.1 116326562 4405803 15458..18214 1 NC_008505.1 hypothetical protein 18214 4405803 LACR_C15 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796483.1 15458 D 272622 CDS YP_796484.1 116326563 4405804 19197..20363 1 NC_008505.1 replication initiator protein 20363 4405804 LACR_C16 Lactococcus lactis subsp. cremoris SK11 replication initiator protein YP_796484.1 19197 D 272622 CDS YP_796485.1 116326564 4405805 20356..20880 1 NC_008505.1 RepB family protein 20880 4405805 LACR_C17 Lactococcus lactis subsp. cremoris SK11 RepB family protein YP_796485.1 20356 D 272622 CDS YP_796486.1 116326565 4405806 complement(21461..22165) 1 NC_008505.1 relaxase/mobilization nuclease domain-containing protein 22165 4405806 LACR_C18 Lactococcus lactis subsp. cremoris SK11 relaxase/mobilization nuclease domain-containing protein YP_796486.1 21461 R 272622 CDS YP_796487.1 116326566 4405807 complement(22727..24526) 1 NC_008505.1 maturase MatR 24526 4405807 LACR_C19 Lactococcus lactis subsp. cremoris SK11 maturase MatR YP_796487.1 22727 R 272622 CDS YP_796488.1 116326567 4405808 complement(25064..25471) 1 NC_008505.1 relaxase/mobilization nuclease domain-containing protein 25471 4405808 LACR_C20 Lactococcus lactis subsp. cremoris SK11 relaxase/mobilization nuclease domain-containing protein YP_796488.1 25064 R 272622 CDS YP_796489.1 116326568 4405809 complement(25476..25844) 1 NC_008505.1 MobC, mobilisation protein (MobC) 25844 4405809 LACR_C21 Lactococcus lactis subsp. cremoris SK11 MobC, mobilisation protein (MobC) YP_796489.1 25476 R 272622 CDS YP_796490.1 116326569 4405810 complement(26139..26405) 1 NC_008505.1 hypothetical protein 26405 4405810 LACR_C22 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796490.1 26139 R 272622 CDS YP_796491.1 116326570 4405811 complement(26424..26675) 1 NC_008505.1 hypothetical protein 26675 4405811 LACR_C23 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796491.1 26424 R 272622 CDS YP_796492.1 116326571 4405812 complement(27663..28298) 1 NC_008505.1 exopolysaccharide biosynthesis protein 28298 4405812 LACR_C24 Lactococcus lactis subsp. cremoris SK11 exopolysaccharide biosynthesis protein YP_796492.1 27663 R 272622 CDS YP_796493.1 116326572 4405814 complement(30431..30727) 1 NC_008505.1 hypothetical protein 30727 4405814 LACR_C26 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796493.1 30431 R 272622 CDS YP_796494.1 116326573 4405815 complement(31440..32087) 1 NC_008505.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 32087 4405815 LACR_C27 Lactococcus lactis subsp. cremoris SK11 pyrrolidone-carboxylate peptidase YP_796494.1 31440 R 272622 CDS YP_796495.1 116326574 4405816 complement(32461..33066) 1 NC_008505.1 dienelactone hydrolase family protein 33066 4405816 LACR_C28 Lactococcus lactis subsp. cremoris SK11 dienelactone hydrolase family protein YP_796495.1 32461 R 272622 CDS YP_796496.1 116326575 4405817 complement(33333..33677) 1 NC_008505.1 hypothetical protein 33677 4405817 LACR_C29 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796496.1 33333 R 272622 CDS YP_796497.1 116326576 4405818 complement(34197..35147) 1 NC_008505.1 Mg2+ and Co2+ transporter 35147 4405818 LACR_C30 Lactococcus lactis subsp. cremoris SK11 Mg2+ and Co2+ transporter YP_796497.1 34197 R 272622 CDS YP_796498.1 116326577 4405819 complement(35278..35436) 1 NC_008505.1 hypothetical protein 35436 4405819 LACR_C31 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796498.1 35278 R 272622 CDS YP_796499.1 116326578 4405820 complement(35678..36358) 1 NC_008505.1 transposase 36358 4405820 LACR_C32 Lactococcus lactis subsp. cremoris SK11 transposase YP_796499.1 35678 R 272622 CDS YP_796500.1 116326579 4405821 36638..38317 1 NC_008505.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 38317 4405821 LACR_C33 Lactococcus lactis subsp. cremoris SK11 D-lactate dehydrogenase YP_796500.1 36638 D 272622 CDS YP_796501.1 116326580 4405822 complement(38405..39301) 1 NC_008505.1 transposase 39301 4405822 LACR_C34 Lactococcus lactis subsp. cremoris SK11 transposase YP_796501.1 38405 R 272622 CDS YP_796502.1 116326581 4405823 complement(40077..41426) 1 NC_008505.1 acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase 41426 4405823 LACR_C35 Lactococcus lactis subsp. cremoris SK11 acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase YP_796502.1 40077 R 272622 CDS YP_796503.1 116326582 4405824 complement(41564..42187) 1 NC_008505.1 amidase 42187 4405824 LACR_C36 Lactococcus lactis subsp. cremoris SK11 amidase YP_796503.1 41564 R 272622 CDS YP_796504.1 116326583 4405825 complement(42453..43028) 1 NC_008505.1 transcriptional regulator 43028 4405825 LACR_C37 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_796504.1 42453 R 272622 CDS YP_796505.1 116326584 4405826 complement(43173..43442) 1 NC_008505.1 hypothetical protein 43442 4405826 LACR_C38 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796505.1 43173 R 272622 CDS YP_796506.1 116326585 4405827 complement(43629..43991) 1 NC_008505.1 hypothetical protein 43991 4405827 LACR_C39 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796506.1 43629 R 272622 CDS YP_796507.1 116326586 4405828 complement(44001..44231) 1 NC_008505.1 hypothetical protein 44231 4405828 LACR_C40 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796507.1 44001 R 272622 CDS YP_796508.1 116326587 4405829 44401..45081 1 NC_008505.1 transposase 45081 4405829 LACR_C41 Lactococcus lactis subsp. cremoris SK11 transposase YP_796508.1 44401 D 272622 CDS YP_796509.1 116326588 4405830 complement(45329..51217) 1 NC_008505.1 lactocepin I 51217 4405830 LACR_C42 Lactococcus lactis subsp. cremoris SK11 lactocepin I YP_796509.1 45329 R 272622 CDS YP_796510.1 116326589 4405838 51542..52441 1 NC_008505.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; peptidylprolyl isomerase 52441 prsA 4405838 prsA Lactococcus lactis subsp. cremoris SK11 peptidylprolyl isomerase YP_796510.1 51542 D 272622 CDS YP_796511.1 116326590 4405839 52591..53271 1 NC_008505.1 transposase 53271 4405839 LACR_C44 Lactococcus lactis subsp. cremoris SK11 transposase YP_796511.1 52591 D 272622 CDS YP_796512.1 116326591 4405840 54743..55633 1 NC_008505.1 transposase 55633 4405840 LACR_C45 Lactococcus lactis subsp. cremoris SK11 transposase YP_796512.1 54743 D 272622 CDS YP_796513.1 116326592 4405841 complement(55779..56075) 1 NC_008505.1 hypothetical protein 56075 4405841 LACR_C46 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796513.1 55779 R 272622 CDS YP_796514.1 116326593 4405842 complement(57994..58194) 1 NC_008505.1 cold-shock DNA-binding protein family protein 58194 4405842 LACR_C47 Lactococcus lactis subsp. cremoris SK11 cold-shock DNA-binding protein family protein YP_796514.1 57994 R 272622 CDS YP_796515.1 116326594 4405843 complement(58471..58671) 1 NC_008505.1 cold-shock DNA-binding protein family protein 58671 4405843 LACR_C48 Lactococcus lactis subsp. cremoris SK11 cold-shock DNA-binding protein family protein YP_796515.1 58471 R 272622 CDS YP_796516.1 116326595 4405844 complement(58802..59002) 1 NC_008505.1 hypothetical protein 59002 4405844 LACR_C49 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796516.1 58802 R 272622 CDS YP_796517.1 116326596 4405846 59980..60660 1 NC_008505.1 transposase 60660 4405846 LACR_C51 Lactococcus lactis subsp. cremoris SK11 transposase YP_796517.1 59980 D 272622 CDS YP_796518.1 116326597 4405849 63487..63837 1 NC_008505.1 hypothetical protein 63837 4405849 LACR_C54 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796518.1 63487 D 272622 CDS YP_796519.1 116326598 4405850 64050..64892 1 NC_008505.1 ATPase for chromosome partitioning 64892 4405850 LACR_C55 Lactococcus lactis subsp. cremoris SK11 ATPase for chromosome partitioning YP_796519.1 64050 D 272622 CDS YP_796520.1 116326599 4405851 64969..65172 1 NC_008505.1 hypothetical protein 65172 4405851 LACR_C56 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796520.1 64969 D 272622 CDS YP_796521.1 116326600 4405852 65569..66561 1 NC_008505.1 hypothetical protein 66561 4405852 LACR_C57 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796521.1 65569 D 272622 CDS YP_796522.1 116326601 4405853 67032..67265 1 NC_008505.1 transposase 67265 4405853 LACR_C58 Lactococcus lactis subsp. cremoris SK11 transposase YP_796522.1 67032 D 272622 CDS YP_796523.1 116326602 4405831 67432..68136 1 NC_008505.1 transposase 68136 4405831 LACR_C59 Lactococcus lactis subsp. cremoris SK11 transposase YP_796523.1 67432 D 272622 CDS YP_796524.1 116326603 4405832 complement(68247..69320) 1 NC_008505.1 transposase 69320 4405832 LACR_C60 Lactococcus lactis subsp. cremoris SK11 transposase YP_796524.1 68247 R 272622 CDS YP_796525.1 116326604 4405833 69850..70518 1 NC_008505.1 DNA-binding response regulator 70518 4405833 LACR_C61 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_796525.1 69850 D 272622 CDS YP_796526.1 116326605 4405834 70506..71900 1 NC_008505.1 Signal transduction histidine kinase 71900 4405834 LACR_C62 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_796526.1 70506 D 272622 CDS YP_796527.1 116326606 4405835 72084..72890 1 NC_008505.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 72890 4405835 LACR_C63 Lactococcus lactis subsp. cremoris SK11 prolipoprotein diacylglyceryl transferase YP_796527.1 72084 D 272622 CDS YP_796528.1 116326607 4405836 72895..73110 1 NC_008505.1 hypothetical protein 73110 4405836 LACR_C64 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796528.1 72895 D 272622 CDS YP_796529.1 116326608 4405837 73366..74670 1 NC_008505.1 surface antigen 74670 4405837 LACR_C65 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_796529.1 73366 D 272622 CDS YP_796530.1 116326610 4405893 complement(105..1811) 1 NC_008506.1 cellobiose-specific PTS system IIC component 1811 4405893 LACR_D01 Lactococcus lactis subsp. cremoris SK11 cellobiose-specific PTS system IIC component YP_796530.1 105 R 272622 CDS YP_796531.1 116326611 4405894 complement(1815..2132) 1 NC_008506.1 cellobiose-specific PTS system IIA component 2132 4405894 LACR_D02 Lactococcus lactis subsp. cremoris SK11 cellobiose-specific PTS system IIA component YP_796531.1 1815 R 272622 CDS YP_796532.1 116326612 4405895 complement(2160..3140) 1 NC_008506.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 3140 4405895 LACR_D03 Lactococcus lactis subsp. cremoris SK11 tagatose 1,6-diphosphate aldolase YP_796532.1 2160 R 272622 CDS YP_796533.1 116326613 4405896 complement(3143..4003) 1 NC_008506.1 tagatose-6-phosphate kinase 4003 4405896 LACR_D04 Lactococcus lactis subsp. cremoris SK11 tagatose-6-phosphate kinase YP_796533.1 3143 R 272622 CDS YP_796534.1 116326614 4405897 complement(4086..4601) 1 NC_008506.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 4601 4405897 LACR_D05 Lactococcus lactis subsp. cremoris SK11 galactose-6-phosphate isomerase subunit LacB YP_796534.1 4086 R 272622 CDS YP_796535.1 116326615 4405898 complement(4618..4992) 1 NC_008506.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 4992 4405898 LACR_D06 Lactococcus lactis subsp. cremoris SK11 galactose-6-phosphate isomerase subunit LacA YP_796535.1 4618 R 272622 CDS YP_796536.1 116326616 4405899 5532..6299 1 NC_008506.1 lactose transport regulator 6299 4405899 LACR_D07 Lactococcus lactis subsp. cremoris SK11 lactose transport regulator YP_796536.1 5532 D 272622 CDS YP_796537.1 116326617 4405861 complement(6798..7379) 1 NC_008506.1 site-specific recombinase, DNA invertase Pin related protein 7379 4405861 LACR_D08 Lactococcus lactis subsp. cremoris SK11 site-specific recombinase, DNA invertase Pin related protein YP_796537.1 6798 R 272622 CDS YP_796538.1 116326618 4405862 7472..7732 1 NC_008506.1 transposase 7732 4405862 LACR_D09 Lactococcus lactis subsp. cremoris SK11 transposase YP_796538.1 7472 D 272622 CDS YP_796539.1 116326619 4405865 complement(8113..9927) 1 NC_008506.1 oligopeptidase F 9927 4405865 LACR_D12 Lactococcus lactis subsp. cremoris SK11 oligopeptidase F YP_796539.1 8113 R 272622 CDS YP_796540.1 116326620 4405866 10533..11243 1 NC_008506.1 transposase 11243 4405866 LACR_D13 Lactococcus lactis subsp. cremoris SK11 transposase YP_796540.1 10533 D 272622 CDS YP_796541.1 116326621 4405867 11636..13990 1 NC_008506.1 carbon starvation protein, membrane protein 13990 4405867 LACR_D14 Lactococcus lactis subsp. cremoris SK11 carbon starvation protein, membrane protein YP_796541.1 11636 D 272622 CDS YP_796542.1 116326622 4405868 14556..15110 1 NC_008506.1 site-specific recombinase, DNA invertase Pin related protein 15110 4405868 LACR_D15 Lactococcus lactis subsp. cremoris SK11 site-specific recombinase, DNA invertase Pin related protein YP_796542.1 14556 D 272622 CDS YP_796543.1 116326623 4405869 complement(16259..18142) 1 NC_008506.1 oligopeptidase O1 18142 4405869 LACR_D16 Lactococcus lactis subsp. cremoris SK11 oligopeptidase O1 YP_796543.1 16259 R 272622 CDS YP_796544.1 116326624 4405870 complement(18267..20069) 1 NC_008506.1 ABC-type oligopeptide transport system, periplasmic component 20069 4405870 LACR_D17 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, periplasmic component YP_796544.1 18267 R 272622 CDS YP_796545.1 116326625 4405871 complement(20179..21063) 1 NC_008506.1 ABC-type dipeptide/oligopeptide/nickel transport system, permease component 21063 4405871 LACR_D18 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, permease component YP_796545.1 20179 R 272622 CDS YP_796546.1 116326626 4405872 complement(21073..22032) 1 NC_008506.1 ABC-type dipeptide/oligopeptide/nickel transport system, permease component 22032 4405872 LACR_D19 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, permease component YP_796546.1 21073 R 272622 CDS YP_796547.1 116326627 4405873 complement(22013..22972) 1 NC_008506.1 ABC-type oligopeptide transport system, ATPase component 22972 4405873 LACR_D20 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, ATPase component YP_796547.1 22013 R 272622 CDS YP_796548.1 116326628 4405874 complement(22969..23985) 1 NC_008506.1 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component 23985 4405874 LACR_D21 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_796548.1 22969 R 272622 CDS YP_796549.1 116326629 4405875 24263..25153 1 NC_008506.1 transposase 25153 4405875 LACR_D22 Lactococcus lactis subsp. cremoris SK11 transposase YP_796549.1 24263 D 272622 CDS YP_796550.1 116326630 4405876 25430..26584 1 NC_008506.1 replication initiator protein 26584 4405876 LACR_D23 Lactococcus lactis subsp. cremoris SK11 replication initiator protein YP_796550.1 25430 D 272622 CDS YP_796551.1 116326631 4405877 26730..27539 1 NC_008506.1 ATPase for chromosome partitioning 27539 4405877 LACR_D24 Lactococcus lactis subsp. cremoris SK11 ATPase for chromosome partitioning YP_796551.1 26730 D 272622 CDS YP_796552.1 116326632 4405879 complement(31189..31572) 1 NC_008506.1 hypothetical protein 31572 4405879 LACR_D26 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796552.1 31189 R 272622 CDS YP_796553.1 116326633 4405880 complement(31578..31859) 1 NC_008506.1 hypothetical protein 31859 4405880 LACR_D27 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796553.1 31578 R 272622 CDS YP_796554.1 116326634 4405881 32107..34128 1 NC_008506.1 hypothetical protein 34128 4405881 LACR_D28 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796554.1 32107 D 272622 CDS YP_796555.1 116326635 4405882 complement(34184..34864) 1 NC_008506.1 transposase 34864 4405882 LACR_D29 Lactococcus lactis subsp. cremoris SK11 transposase YP_796555.1 34184 R 272622 CDS YP_796556.1 116326636 4405883 35324..36901 1 NC_008506.1 manganese transporter NRAMP 36901 4405883 LACR_D30 Lactococcus lactis subsp. cremoris SK11 manganese transporter NRAMP YP_796556.1 35324 D 272622 CDS YP_796557.1 116326637 4405884 36910..37347 1 NC_008506.1 universal stress protein UspA-like nucleotide-binding protein 37347 4405884 LACR_D31 Lactococcus lactis subsp. cremoris SK11 universal stress protein UspA-like nucleotide-binding protein YP_796557.1 36910 D 272622 CDS YP_796558.1 116326638 4405885 complement(37460..38140) 1 NC_008506.1 transposase 38140 4405885 LACR_D32 Lactococcus lactis subsp. cremoris SK11 transposase YP_796558.1 37460 R 272622 CDS YP_796559.1 116326639 4405886 complement(38635..39465) 1 NC_008506.1 aminoglycoside N3'-acetyltransferase 39465 4405886 LACR_D33 Lactococcus lactis subsp. cremoris SK11 aminoglycoside N3'-acetyltransferase YP_796559.1 38635 R 272622 CDS YP_796560.1 116326640 4405887 complement(39548..40438) 1 NC_008506.1 transposase 40438 4405887 LACR_D34 Lactococcus lactis subsp. cremoris SK11 transposase YP_796560.1 39548 R 272622 CDS YP_796561.1 116326641 4405888 complement(40727..41698) 1 NC_008506.1 tellurite resistance protein related permease 41698 4405888 LACR_D35 Lactococcus lactis subsp. cremoris SK11 tellurite resistance protein related permease YP_796561.1 40727 R 272622 CDS YP_796562.1 116326642 4405889 complement(41817..42671) 1 NC_008506.1 transposase 42671 4405889 LACR_D36 Lactococcus lactis subsp. cremoris SK11 transposase YP_796562.1 41817 R 272622 CDS YP_796563.1 116326643 4405891 complement(44611..45516) 1 NC_008506.1 galactose mutarotase-like protein 45516 4405891 LACR_D38 Lactococcus lactis subsp. cremoris SK11 galactose mutarotase-like protein YP_796563.1 44611 R 272622 CDS YP_796564.1 116326644 4405892 complement(45802..47208) 1 NC_008506.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 47208 4405892 LACR_D39 Lactococcus lactis subsp. cremoris SK11 6-phospho-beta-galactosidase YP_796564.1 45802 R 272622 CDS YP_796565.1 116326646 4405901 complement(939..2015) 1 NC_008507.1 DNA segregation ATPase FtsK/SpoIIIE related protein 2015 4405901 LACR_E1 Lactococcus lactis subsp. cremoris SK11 DNA segregation ATPase FtsK/SpoIIIE related protein YP_796565.1 939 R 272622 CDS YP_796566.1 116326647 4405902 complement(2015..2335) 1 NC_008507.1 hypothetical protein 2335 4405902 LACR_E2 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796566.1 2015 R 272622 CDS YP_796567.1 116326648 4405903 complement(2464..2961) 1 NC_008507.1 hypothetical protein 2961 4405903 LACR_E3 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796567.1 2464 R 272622 CDS YP_796568.1 116326649 4405904 3297..4058 1 NC_008507.1 hypothetical protein 4058 4405904 LACR_E4 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796568.1 3297 D 272622 CDS YP_796569.1 116326650 4405905 complement(4299..5210) 1 NC_008507.1 hypothetical protein 5210 4405905 LACR_E5 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796569.1 4299 R 272622 CDS YP_796570.1 116326651 4405906 complement(5228..9910) 1 NC_008507.1 superfamily II DNA/RNA helicase 9910 4405906 LACR_E6 Lactococcus lactis subsp. cremoris SK11 superfamily II DNA/RNA helicase YP_796570.1 5228 R 272622 CDS YP_796571.1 116326652 4405907 complement(9907..10581) 1 NC_008507.1 hypothetical protein 10581 4405907 LACR_E7 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_796571.1 9907 R 272622 CDS YP_796572.1 116326653 4405900 complement(10574..11905) 1 NC_008507.1 replication initiator protein 11905 4405900 LACR_E8 Lactococcus lactis subsp. cremoris SK11 replication initiator protein YP_796572.1 10574 R 272622 CDS YP_808060.1 116510844 4433303 144..1508 1 NC_008527.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1508 dnaA 4433303 dnaA Lactococcus lactis subsp. cremoris SK11 chromosomal replication initiation protein YP_808060.1 144 D 272622 CDS YP_808061.1 116510845 4433304 1665..2807 1 NC_008527.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2807 4433304 LACR_0002 Lactococcus lactis subsp. cremoris SK11 DNA polymerase III subunit beta YP_808061.1 1665 D 272622 CDS YP_808062.1 116510846 4433305 2913..6212 1 NC_008527.1 DNA helicase/exodeoxyribonuclease V, subunit B 6212 4433305 LACR_0003 Lactococcus lactis subsp. cremoris SK11 DNA helicase/exodeoxyribonuclease V, subunit B YP_808062.1 2913 D 272622 CDS YP_808063.1 116510847 4432914 6205..9816 1 NC_008527.1 DNA helicase/exodeoxyribonuclease V, subunit A 9816 4432914 LACR_0004 Lactococcus lactis subsp. cremoris SK11 DNA helicase/exodeoxyribonuclease V, subunit A YP_808063.1 6205 D 272622 CDS YP_808064.1 116510848 4432915 9851..10051 1 NC_008527.1 hypothetical protein 10051 4432915 LACR_0005 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808064.1 9851 D 272622 CDS YP_808065.1 116510849 4432916 complement(10059..10616) 1 NC_008527.1 XRE family transcriptional regulator 10616 4432916 LACR_0006 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_808065.1 10059 R 272622 CDS YP_808066.1 116510850 4432917 10900..12015 1 NC_008527.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 12015 4432917 LACR_0007 Lactococcus lactis subsp. cremoris SK11 GTP-dependent nucleic acid-binding protein EngD YP_808066.1 10900 D 272622 CDS YP_808067.1 116510851 4432918 12127..12450 1 NC_008527.1 XRE family transcriptional regulator 12450 4432918 LACR_0008 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_808067.1 12127 D 272622 CDS YP_808068.1 116510852 4432919 12882..13856 1 NC_008527.1 hypothetical protein 13856 4432919 LACR_0009 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808068.1 12882 D 272622 CDS YP_808069.1 116510853 4432920 14033..14599 1 NC_008527.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 14599 4432920 LACR_0010 Lactococcus lactis subsp. cremoris SK11 peptidyl-tRNA hydrolase YP_808069.1 14033 D 272622 CDS YP_808070.1 116510854 4432921 14600..18088 1 NC_008527.1 transcription-repair coupling factor 18088 4432921 LACR_0011 Lactococcus lactis subsp. cremoris SK11 transcription-repair coupling factor YP_808070.1 14600 D 272622 CDS YP_808071.1 116510855 4432922 18405..18674 1 NC_008527.1 ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4-like protein 18674 4432922 LACR_0012 Lactococcus lactis subsp. cremoris SK11 ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4-like protein YP_808071.1 18405 D 272622 CDS YP_808072.1 116510856 4432923 18705..19079 1 NC_008527.1 hypothetical protein 19079 4432923 LACR_0013 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808072.1 18705 D 272622 CDS YP_808073.1 116510857 4432924 19079..19402 1 NC_008527.1 hypothetical protein 19402 4432924 LACR_0014 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808073.1 19079 D 272622 CDS YP_808074.1 116510858 4432925 19543..20880 1 NC_008527.1 Beta-lactamase class A 20880 4432925 LACR_0015 Lactococcus lactis subsp. cremoris SK11 Beta-lactamase class A YP_808074.1 19543 D 272622 CDS YP_808075.1 116510859 4432926 20877..22145 1 NC_008527.1 tRNA(Ile)-lysidine synthetase, MesJ 22145 4432926 LACR_0016 Lactococcus lactis subsp. cremoris SK11 tRNA(Ile)-lysidine synthetase, MesJ YP_808075.1 20877 D 272622 CDS YP_808076.1 116510860 4432927 22126..22677 1 NC_008527.1 hypoxanthine phosphoribosyltransferase 22677 4432927 LACR_0017 Lactococcus lactis subsp. cremoris SK11 hypoxanthine phosphoribosyltransferase YP_808076.1 22126 D 272622 CDS YP_808077.1 116510861 4432928 22883..24970 1 NC_008527.1 FtsH-2 peptidase 24970 4432928 LACR_0018 Lactococcus lactis subsp. cremoris SK11 FtsH-2 peptidase YP_808077.1 22883 D 272622 CDS YP_808078.1 116510862 4432875 26036..27859 1 NC_008527.1 phosphotransferase system, mannitol-specific IIBC component 27859 4432875 LACR_0027 Lactococcus lactis subsp. cremoris SK11 phosphotransferase system, mannitol-specific IIBC component YP_808078.1 26036 D 272622 CDS YP_808079.1 116510863 4432876 27919..29853 1 NC_008527.1 transcriptional antiterminator 29853 4432876 LACR_0028 Lactococcus lactis subsp. cremoris SK11 transcriptional antiterminator YP_808079.1 27919 D 272622 CDS YP_808080.1 116510864 4432877 29900..30331 1 NC_008527.1 mannitol/fructose-specific phosphotransferase system IIA protein 30331 4432877 LACR_0029 Lactococcus lactis subsp. cremoris SK11 mannitol/fructose-specific phosphotransferase system IIA protein YP_808080.1 29900 D 272622 CDS YP_808081.1 116510865 4433611 30480..31646 1 NC_008527.1 mannitol-1-phosphate 5-dehydrogenase 31646 4433611 LACR_0030 Lactococcus lactis subsp. cremoris SK11 mannitol-1-phosphate 5-dehydrogenase YP_808081.1 30480 D 272622 CDS YP_808082.1 116510866 4433612 31752..32015 1 NC_008527.1 hypothetical protein 32015 4433612 LACR_0031 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808082.1 31752 D 272622 CDS YP_808083.1 116510867 4433613 complement(32064..32333) 1 NC_008527.1 hypothetical protein 32333 4433613 LACR_0032 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808083.1 32064 R 272622 CDS YP_808084.1 116510868 4433614 complement(32305..33135) 1 NC_008527.1 alpha/beta hydrolase superfamily protein 33135 4433614 LACR_0033 Lactococcus lactis subsp. cremoris SK11 alpha/beta hydrolase superfamily protein YP_808084.1 32305 R 272622 CDS YP_808085.1 116510869 4433615 33891..34142 1 NC_008527.1 hypothetical protein 34142 4433615 LACR_0034 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808085.1 33891 D 272622 CDS YP_808086.1 116510870 4433616 34547..34849 1 NC_008527.1 hypothetical protein 34849 4433616 LACR_0035 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808086.1 34547 D 272622 CDS YP_808087.1 116510871 4433617 35076..35429 1 NC_008527.1 hypothetical protein 35429 4433617 LACR_0036 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808087.1 35076 D 272622 CDS YP_808088.1 116510872 4433618 35551..35709 1 NC_008527.1 hypothetical protein 35709 4433618 LACR_0037 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808088.1 35551 D 272622 CDS YP_808089.1 116510873 4433619 complement(35769..36623) 1 NC_008527.1 transposase 36623 4433619 LACR_0038 Lactococcus lactis subsp. cremoris SK11 transposase YP_808089.1 35769 R 272622 CDS YP_808090.1 116510874 4433620 complement(36620..36880) 1 NC_008527.1 transposase 36880 4433620 LACR_0039 Lactococcus lactis subsp. cremoris SK11 transposase YP_808090.1 36620 R 272622 CDS YP_808091.1 116510875 4433621 37363..37815 1 NC_008527.1 acetyltransferase 37815 4433621 LACR_0040 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808091.1 37363 D 272622 CDS YP_808092.1 116510876 4433622 37900..38142 1 NC_008527.1 hypothetical protein 38142 4433622 LACR_0041 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808092.1 37900 D 272622 CDS YP_808093.1 116510877 4433623 complement(38236..38847) 1 NC_008527.1 MFS superfamily sulfate permease 38847 4433623 LACR_0042 Lactococcus lactis subsp. cremoris SK11 MFS superfamily sulfate permease YP_808093.1 38236 R 272622 CDS YP_808094.1 116510878 4433624 complement(38844..39854) 1 NC_008527.1 MFS superfamily sulfate permease 39854 4433624 LACR_0043 Lactococcus lactis subsp. cremoris SK11 MFS superfamily sulfate permease YP_808094.1 38844 R 272622 CDS YP_808095.1 116510879 4433625 40064..40585 1 NC_008527.1 acetyltransferase 40585 4433625 LACR_0044 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808095.1 40064 D 272622 CDS YP_808096.1 116510880 4433627 41047..42222 1 NC_008527.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 42222 4433627 LACR_0046 Lactococcus lactis subsp. cremoris SK11 aromatic amino acid aminotransferase YP_808096.1 41047 D 272622 CDS YP_808097.1 116510881 4434634 42320..43075 1 NC_008527.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 43075 recO 4434634 recO Lactococcus lactis subsp. cremoris SK11 DNA repair protein RecO YP_808097.1 42320 D 272622 CDS YP_808098.1 116510882 4434635 complement(43227..44645) 1 NC_008527.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 44645 4434635 LACR_0048 Lactococcus lactis subsp. cremoris SK11 dihydrolipoamide dehydrogenase YP_808098.1 43227 R 272622 CDS YP_808099.1 116510883 4434636 complement(44864..46450) 1 NC_008527.1 acetoin/pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase 46450 4434636 LACR_0049 Lactococcus lactis subsp. cremoris SK11 acetoin/pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase YP_808099.1 44864 R 272622 CDS YP_808100.1 116510884 4434637 complement(46443..47423) 1 NC_008527.1 acetoin dehydrogenase complex, E1 component, beta subunit 47423 4434637 LACR_0050 Lactococcus lactis subsp. cremoris SK11 acetoin dehydrogenase complex, E1 component, beta subunit YP_808100.1 46443 R 272622 CDS YP_808101.1 116510885 4434638 complement(47426..48550) 1 NC_008527.1 acetoin dehydrogenase complex, E1 component, alpha subunit 48550 4434638 LACR_0051 Lactococcus lactis subsp. cremoris SK11 acetoin dehydrogenase complex, E1 component, alpha subunit YP_808101.1 47426 R 272622 CDS YP_808102.1 116510886 4434639 complement(48639..49640) 1 NC_008527.1 lipoate-protein ligase 49640 4434639 LACR_0052 Lactococcus lactis subsp. cremoris SK11 lipoate-protein ligase YP_808102.1 48639 R 272622 CDS YP_808103.1 116510887 4434640 complement(49833..50687) 1 NC_008527.1 glycerophosphoryl diester phosphodiesterase 50687 4434640 LACR_0053 Lactococcus lactis subsp. cremoris SK11 glycerophosphoryl diester phosphodiesterase YP_808103.1 49833 R 272622 CDS YP_808104.1 116510888 4434641 complement(50687..50785) 1 NC_008527.1 hypothetical protein 50785 4434641 LACR_0054 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808104.1 50687 R 272622 CDS YP_808105.1 116510889 4434643 complement(51467..51793) 1 NC_008527.1 hypothetical protein 51793 4434643 LACR_0056 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808105.1 51467 R 272622 CDS YP_808106.1 116510890 4434644 complement(51850..52740) 1 NC_008527.1 transposase 52740 4434644 LACR_0057 Lactococcus lactis subsp. cremoris SK11 transposase YP_808106.1 51850 R 272622 CDS YP_808107.1 116510891 4434645 complement(52893..53918) 1 NC_008527.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 53918 4434645 LACR_0058 Lactococcus lactis subsp. cremoris SK11 tryptophanyl-tRNA synthetase II YP_808107.1 52893 R 272622 CDS YP_808108.1 116510892 4434646 54417..54854 1 NC_008527.1 redox protein, regulator of disulfide bond formation 54854 4434646 LACR_0059 Lactococcus lactis subsp. cremoris SK11 redox protein, regulator of disulfide bond formation YP_808108.1 54417 D 272622 CDS YP_808109.1 116510893 4434647 55016..56329 1 NC_008527.1 amino acid transporter 56329 4434647 LACR_0060 Lactococcus lactis subsp. cremoris SK11 amino acid transporter YP_808109.1 55016 D 272622 CDS YP_808110.1 116510894 4434648 complement(56408..57403) 1 NC_008527.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 57403 4434648 LACR_0061 Lactococcus lactis subsp. cremoris SK11 putative glycerol-3-phosphate acyltransferase PlsX YP_808110.1 56408 R 272622 CDS YP_808111.1 116510895 4434649 complement(57506..58318) 1 NC_008527.1 HAD superfamily hydrolase 58318 4434649 LACR_0062 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_808111.1 57506 R 272622 CDS YP_808112.1 116510896 4434650 complement(58767..60404) 1 NC_008527.1 ABC transporter ATPase 60404 4434650 LACR_0063 Lactococcus lactis subsp. cremoris SK11 ABC transporter ATPase YP_808112.1 58767 R 272622 CDS YP_808113.1 116510897 4432966 60904..61158 1 NC_008527.1 hypothetical protein 61158 4432966 LACR_0064 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808113.1 60904 D 272622 CDS YP_808114.1 116510898 4432967 complement(61277..62101) 1 NC_008527.1 Short-chain dehydrogenase of various substrate specificities 62101 4432967 LACR_0065 Lactococcus lactis subsp. cremoris SK11 Short-chain dehydrogenase of various substrate specificities YP_808114.1 61277 R 272622 CDS YP_808115.1 116510899 4432968 complement(62261..62842) 1 NC_008527.1 transcriptional regulator 62842 4432968 LACR_0066 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808115.1 62261 R 272622 CDS YP_808116.1 116510900 4432969 complement(63030..63512) 1 NC_008527.1 hypothetical protein 63512 4432969 LACR_0067 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808116.1 63030 R 272622 CDS YP_808117.1 116510901 4432970 complement(63769..65049) 1 NC_008527.1 O-acetylhomoserine sulfhydrylase 65049 4432970 LACR_0068 Lactococcus lactis subsp. cremoris SK11 O-acetylhomoserine sulfhydrylase YP_808117.1 63769 R 272622 CDS YP_808118.1 116510902 4432971 complement(65315..66148) 1 NC_008527.1 Short-chain dehydrogenase of various substrate specificities 66148 4432971 LACR_0069 Lactococcus lactis subsp. cremoris SK11 Short-chain dehydrogenase of various substrate specificities YP_808118.1 65315 R 272622 CDS YP_808119.1 116510903 4432972 complement(66497..67387) 1 NC_008527.1 transposase 67387 4432972 LACR_0070 Lactococcus lactis subsp. cremoris SK11 transposase YP_808119.1 66497 R 272622 CDS YP_808120.1 116510904 4432973 67560..68027 1 NC_008527.1 universal stress protein UspA-like nucleotide-binding protein 68027 4432973 LACR_0071 Lactococcus lactis subsp. cremoris SK11 universal stress protein UspA-like nucleotide-binding protein YP_808120.1 67560 D 272622 CDS YP_808121.1 116510905 4432974 68154..68351 1 NC_008527.1 hypothetical protein 68351 4432974 LACR_0072 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808121.1 68154 D 272622 CDS YP_808122.1 116510906 4432975 68387..69007 1 NC_008527.1 esterase 69007 4432975 LACR_0073 Lactococcus lactis subsp. cremoris SK11 esterase YP_808122.1 68387 D 272622 CDS YP_808123.1 116510907 4432976 69075..70244 1 NC_008527.1 lactoylglutathione lyase related lyase 70244 4432976 LACR_0074 Lactococcus lactis subsp. cremoris SK11 lactoylglutathione lyase related lyase YP_808123.1 69075 D 272622 CDS YP_808124.1 116510908 4432977 70255..70845 1 NC_008527.1 hypothetical protein 70845 4432977 LACR_0075 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808124.1 70255 D 272622 CDS YP_808125.1 116510909 4432978 complement(70927..71076) 1 NC_008527.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 71076 rpmG 4432978 rpmG Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L33 YP_808125.1 70927 R 272622 CDS YP_808126.1 116510910 4432979 complement(71106..71279) 1 NC_008527.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 71279 rpmF 4432979 rpmF Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L32 YP_808126.1 71106 R 272622 CDS YP_808127.1 116510911 4432980 71641..73422 1 NC_008527.1 cation transport ATPase 73422 4432980 LACR_0078 Lactococcus lactis subsp. cremoris SK11 cation transport ATPase YP_808127.1 71641 D 272622 CDS YP_808128.1 116510912 4432981 73609..74088 1 NC_008527.1 hypothetical protein 74088 4432981 LACR_0079 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808128.1 73609 D 272622 CDS YP_808129.1 116510913 4432982 74088..74456 1 NC_008527.1 hypothetical protein 74456 4432982 LACR_0080 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808129.1 74088 D 272622 CDS YP_808130.1 116510914 4432983 complement(74466..75251) 1 NC_008527.1 chromosome segregation DNA-binding protein 75251 4432983 LACR_0081 Lactococcus lactis subsp. cremoris SK11 chromosome segregation DNA-binding protein YP_808130.1 74466 R 272622 CDS YP_808131.1 116510915 4433442 complement(75306..76565) 1 NC_008527.1 recombination factor protein RarA 76565 4433442 LACR_0082 Lactococcus lactis subsp. cremoris SK11 recombination factor protein RarA YP_808131.1 75306 R 272622 CDS YP_808132.1 116510916 4433443 complement(76609..77097) 1 NC_008527.1 acetyltransferase 77097 4433443 LACR_0083 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808132.1 76609 R 272622 CDS YP_808133.1 116510917 4433444 77270..77737 1 NC_008527.1 hypothetical protein 77737 4433444 LACR_0084 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808133.1 77270 D 272622 CDS YP_808134.1 116510918 4433445 77767..79320 1 NC_008527.1 ABC transporter ATPase 79320 4433445 LACR_0085 Lactococcus lactis subsp. cremoris SK11 ABC transporter ATPase YP_808134.1 77767 D 272622 CDS YP_808135.1 116510919 4433446 79395..79679 1 NC_008527.1 hypothetical protein 79679 4433446 LACR_0086 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808135.1 79395 D 272622 CDS YP_808136.1 116510920 4433447 79713..80453 1 NC_008527.1 SAM-dependent methyltransferase 80453 4433447 LACR_0087 Lactococcus lactis subsp. cremoris SK11 SAM-dependent methyltransferase YP_808136.1 79713 D 272622 CDS YP_808137.1 116510921 4433448 80440..80928 1 NC_008527.1 hypothetical protein 80928 4433448 LACR_0088 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808137.1 80440 D 272622 CDS YP_808138.1 116510922 4433449 80941..81894 1 NC_008527.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 81894 prmA 4433449 prmA Lactococcus lactis subsp. cremoris SK11 ribosomal protein L11 methyltransferase YP_808138.1 80941 D 272622 CDS YP_808139.1 116510923 4433450 82014..82766 1 NC_008527.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 82766 4433450 LACR_0090 Lactococcus lactis subsp. cremoris SK11 16S ribosomal RNA methyltransferase RsmE YP_808139.1 82014 D 272622 CDS YP_808140.1 116510924 4433451 82796..83752 1 NC_008527.1 xylanase/chitin deacetylase 83752 4433451 LACR_0091 Lactococcus lactis subsp. cremoris SK11 xylanase/chitin deacetylase YP_808140.1 82796 D 272622 CDS YP_808141.1 116510925 4433452 83953..86175 1 NC_008527.1 guanosine polyphosphate pyrophosphohydrolase/synthetase 86175 4433452 LACR_0092 Lactococcus lactis subsp. cremoris SK11 guanosine polyphosphate pyrophosphohydrolase/synthetase YP_808141.1 83953 D 272622 CDS YP_808142.1 116510926 4433454 87382..87837 1 NC_008527.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 87837 4433454 LACR_0094 Lactococcus lactis subsp. cremoris SK11 D-tyrosyl-tRNA(Tyr) deacylase YP_808142.1 87382 D 272622 CDS YP_808143.1 116510927 4433455 87830..88834 1 NC_008527.1 hypothetical protein 88834 4433455 LACR_0095 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808143.1 87830 D 272622 CDS YP_808144.1 116510928 4433456 88837..89460 1 NC_008527.1 HAD superfamily hydrolase 89460 4433456 LACR_0096 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_808144.1 88837 D 272622 CDS YP_808145.1 116510929 4433457 89594..90991 1 NC_008527.1 amino acid transporter 90991 4433457 LACR_0097 Lactococcus lactis subsp. cremoris SK11 amino acid transporter YP_808145.1 89594 D 272622 CDS YP_808146.1 116510930 4433458 91161..91802 1 NC_008527.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 91802 4433458 LACR_0098 Lactococcus lactis subsp. cremoris SK11 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_808146.1 91161 D 272622 CDS YP_808147.1 116510931 4432499 complement(91833..92342) 1 NC_008527.1 transcriptional regulator 92342 4432499 LACR_0099 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808147.1 91833 R 272622 CDS YP_808148.1 116510932 4432501 93327..95924 1 NC_008527.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 95924 secA 4432501 secA Lactococcus lactis subsp. cremoris SK11 preprotein translocase subunit SecA YP_808148.1 93327 D 272622 CDS YP_808149.1 116510933 4432502 96054..97091 1 NC_008527.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 97091 4432502 LACR_0102 Lactococcus lactis subsp. cremoris SK11 phospho-2-dehydro-3-deoxyheptonate aldolase YP_808149.1 96054 D 272622 CDS YP_808150.1 116510934 4432503 97340..97606 1 NC_008527.1 phosphocarrier protein HPr 97606 4432503 LACR_0103 Lactococcus lactis subsp. cremoris SK11 phosphocarrier protein HPr YP_808150.1 97340 D 272622 CDS YP_808151.1 116510935 4432504 97609..99336 1 NC_008527.1 phosphoenolpyruvate-protein phosphotransferase 99336 4432504 LACR_0104 Lactococcus lactis subsp. cremoris SK11 phosphoenolpyruvate-protein phosphotransferase YP_808151.1 97609 D 272622 CDS YP_808152.1 116510936 4432505 99511..99819 1 NC_008527.1 hypothetical protein 99819 4432505 LACR_0105 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808152.1 99511 D 272622 CDS YP_808153.1 116510937 4432506 complement(99909..100208) 1 NC_008527.1 hypothetical protein 100208 4432506 LACR_0106 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808153.1 99909 R 272622 CDS YP_808154.1 116510938 4432507 100313..100600 1 NC_008527.1 serine hydroxymethyltransferase/phosphoribosyl-dephospho-CoA transferase family protein 100600 4432507 LACR_0107 Lactococcus lactis subsp. cremoris SK11 serine hydroxymethyltransferase/phosphoribosyl-dephospho-CoA transferase family protein YP_808154.1 100313 D 272622 CDS YP_808155.1 116510939 4432509 complement(100880..101815) 1 NC_008527.1 alpha/beta fold family hydrolase 101815 4432509 LACR_0109 Lactococcus lactis subsp. cremoris SK11 alpha/beta fold family hydrolase YP_808155.1 100880 R 272622 CDS YP_808156.1 116510940 4432510 101956..102414 1 NC_008527.1 surface antigen 102414 4432510 LACR_0110 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_808156.1 101956 D 272622 CDS YP_808157.1 116510941 4432511 102583..103365 1 NC_008527.1 hypothetical protein 103365 4432511 LACR_0111 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808157.1 102583 D 272622 CDS YP_808158.1 116510942 4432512 103551..103871 1 NC_008527.1 membrane transporter 103871 4432512 LACR_0112 Lactococcus lactis subsp. cremoris SK11 membrane transporter YP_808158.1 103551 D 272622 CDS YP_808159.1 116510943 4432513 103994..105157 1 NC_008527.1 major facilitator superfamily permease 105157 4432513 LACR_0113 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808159.1 103994 D 272622 CDS YP_808160.1 116510944 4432514 105540..105800 1 NC_008527.1 transposase 105800 4432514 LACR_0114 Lactococcus lactis subsp. cremoris SK11 transposase YP_808160.1 105540 D 272622 CDS YP_808161.1 116510945 4432515 105797..106642 1 NC_008527.1 transposase 106642 4432515 LACR_0115 Lactococcus lactis subsp. cremoris SK11 transposase YP_808161.1 105797 D 272622 CDS YP_808162.1 116510946 4433393 106727..107902 1 NC_008527.1 transposase 107902 4433393 LACR_0116 Lactococcus lactis subsp. cremoris SK11 transposase YP_808162.1 106727 D 272622 CDS YP_808163.1 116510947 4433395 108942..110177 1 NC_008527.1 hypothetical protein 110177 4433395 LACR_0118 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808163.1 108942 D 272622 CDS YP_808164.1 116510948 4433396 110318..110500 1 NC_008527.1 hypothetical protein 110500 4433396 LACR_0119 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808164.1 110318 D 272622 CDS YP_808165.1 116510949 4433397 110576..110716 1 NC_008527.1 hypothetical protein 110716 4433397 LACR_0120 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808165.1 110576 D 272622 CDS YP_808166.1 116510950 4433398 complement(110768..111622) 1 NC_008527.1 transposase 111622 4433398 LACR_0121 Lactococcus lactis subsp. cremoris SK11 transposase YP_808166.1 110768 R 272622 CDS YP_808167.1 116510951 4433399 complement(111619..111879) 1 NC_008527.1 transposase 111879 4433399 LACR_0122 Lactococcus lactis subsp. cremoris SK11 transposase YP_808167.1 111619 R 272622 CDS YP_808168.1 116510952 4433402 114024..115217 1 NC_008527.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 115217 4433402 LACR_0125 Lactococcus lactis subsp. cremoris SK11 argininosuccinate synthase YP_808168.1 114024 D 272622 CDS YP_808169.1 116510953 4433403 115246..116625 1 NC_008527.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 116625 4433403 LACR_0126 Lactococcus lactis subsp. cremoris SK11 argininosuccinate lyase YP_808169.1 115246 D 272622 CDS YP_808170.1 116510954 4433404 complement(116642..117838) 1 NC_008527.1 major facilitator superfamily permease 117838 4433404 LACR_0127 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808170.1 116642 R 272622 CDS YP_808171.1 116510955 4433405 118032..118607 1 NC_008527.1 TetR family transcriptional regulator 118607 4433405 LACR_0128 Lactococcus lactis subsp. cremoris SK11 TetR family transcriptional regulator YP_808171.1 118032 D 272622 CDS YP_808172.1 116510956 4433406 118764..119117 1 NC_008527.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 119117 rnpA 4433406 rnpA Lactococcus lactis subsp. cremoris SK11 ribonuclease P YP_808172.1 118764 D 272622 CDS YP_808173.1 116510957 4433407 119114..119923 1 NC_008527.1 preprotein translocase subunit YidC 119923 4433407 LACR_0130 Lactococcus lactis subsp. cremoris SK11 preprotein translocase subunit YidC YP_808173.1 119114 D 272622 CDS YP_808174.1 116510958 4433408 120011..120925 1 NC_008527.1 hypothetical protein 120925 4433408 LACR_0131 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808174.1 120011 D 272622 CDS YP_808175.1 116510959 4432593 121057..121191 1 NC_008527.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 121191 rpmH 4432593 rpmH Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L34 YP_808175.1 121057 D 272622 CDS YP_808176.1 116510960 4432594 121369..122280 1 NC_008527.1 oxidoreductase 122280 4432594 LACR_0133 Lactococcus lactis subsp. cremoris SK11 oxidoreductase YP_808176.1 121369 D 272622 CDS YP_808177.1 116510961 4432595 122350..122664 1 NC_008527.1 XRE family transcriptional regulator 122664 4432595 LACR_0134 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_808177.1 122350 D 272622 CDS YP_808178.1 116510962 4432596 122841..122999 1 NC_008527.1 hypothetical protein 122999 4432596 LACR_0135 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808178.1 122841 D 272622 CDS YP_808179.1 116510963 4432597 123082..123762 1 NC_008527.1 hypothetical protein 123762 4432597 LACR_0136 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808179.1 123082 D 272622 CDS YP_808180.1 116510964 4432598 124057..124323 1 NC_008527.1 hypothetical protein 124323 4432598 LACR_0137 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808180.1 124057 D 272622 CDS YP_808181.1 116510965 4432599 124323..124754 1 NC_008527.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 124754 4432599 LACR_0138 Lactococcus lactis subsp. cremoris SK11 Holliday junction resolvase-like protein YP_808181.1 124323 D 272622 CDS YP_808182.1 116510966 4432600 124855..125178 1 NC_008527.1 hypothetical protein 125178 4432600 LACR_0139 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808182.1 124855 D 272622 CDS YP_808183.1 116510967 4432601 complement(125208..125726) 1 NC_008527.1 hypothetical protein 125726 4432601 LACR_0140 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808183.1 125208 R 272622 CDS YP_808184.1 116510968 4432602 complement(125723..126460) 1 NC_008527.1 carbonyl reductase 126460 4432602 LACR_0141 Lactococcus lactis subsp. cremoris SK11 carbonyl reductase YP_808184.1 125723 R 272622 CDS YP_808185.1 116510969 4432603 complement(126480..126791) 1 NC_008527.1 hypothetical protein 126791 4432603 LACR_0142 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808185.1 126480 R 272622 CDS YP_808186.1 116510970 4432604 complement(126801..127586) 1 NC_008527.1 Short-chain dehydrogenase (D-alanine transfer protein) 127586 4432604 LACR_0143 Lactococcus lactis subsp. cremoris SK11 Short-chain dehydrogenase (D-alanine transfer protein) YP_808186.1 126801 R 272622 CDS YP_808187.1 116510971 4432605 127705..128250 1 NC_008527.1 TetR family transcriptional regulator 128250 4432605 LACR_0144 Lactococcus lactis subsp. cremoris SK11 TetR family transcriptional regulator YP_808187.1 127705 D 272622 CDS YP_808188.1 116510972 4432606 complement(128316..130259) 1 NC_008527.1 1,4-alpha-glucan branching enzyme 130259 4432606 LACR_0145 Lactococcus lactis subsp. cremoris SK11 1,4-alpha-glucan branching enzyme YP_808188.1 128316 R 272622 CDS YP_808189.1 116510973 4432607 complement(130379..130699) 1 NC_008527.1 hypothetical protein 130699 4432607 LACR_0146 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808189.1 130379 R 272622 CDS YP_808190.1 116510974 4432609 131535..132074 1 NC_008527.1 transcriptional regulator 132074 4432609 LACR_0148 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808190.1 131535 D 272622 CDS YP_808191.1 116510975 4432610 132531..137945 1 NC_008527.1 outer membrane protein 137945 4432610 LACR_0149 Lactococcus lactis subsp. cremoris SK11 outer membrane protein YP_808191.1 132531 D 272622 CDS YP_808192.1 116510976 4432193 139022..139165 1 NC_008527.1 hypothetical protein 139165 4432193 LACR_0150 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808192.1 139022 D 272622 CDS YP_808193.1 116510977 4432194 139323..140453 1 NC_008527.1 cell surface protein 140453 4432194 LACR_0151 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_808193.1 139323 D 272622 CDS YP_808194.1 116510978 4432195 140493..140813 1 NC_008527.1 hypothetical protein 140813 4432195 LACR_0152 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808194.1 140493 D 272622 CDS YP_808195.1 116510979 4432196 complement(140860..140994) 1 NC_008527.1 hypothetical protein 140994 4432196 LACR_0153 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808195.1 140860 R 272622 CDS YP_808196.1 116510980 4432197 141098..141571 1 NC_008527.1 cell surface protein 141571 4432197 LACR_0154 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_808196.1 141098 D 272622 CDS YP_808197.1 116510981 4432198 141678..144425 1 NC_008527.1 hypothetical protein 144425 4432198 LACR_0155 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808197.1 141678 D 272622 CDS YP_808198.1 116510982 4432199 144437..144580 1 NC_008527.1 hypothetical protein 144580 4432199 LACR_0156 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808198.1 144437 D 272622 CDS YP_808199.1 116510983 4432200 144537..144851 1 NC_008527.1 XRE family transcriptional regulator 144851 4432200 LACR_0157 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_808199.1 144537 D 272622 CDS YP_808200.1 116510984 4432202 complement(145140..146288) 1 NC_008527.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 146288 tgt 4432202 tgt Lactococcus lactis subsp. cremoris SK11 queuine tRNA-ribosyltransferase YP_808200.1 145140 R 272622 CDS YP_808201.1 116510985 4432203 146489..147178 1 NC_008527.1 hypothetical protein 147178 4432203 LACR_0160 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808201.1 146489 D 272622 CDS YP_808202.1 116510986 4432204 complement(147233..148411) 1 NC_008527.1 major facilitator superfamily permease 148411 4432204 LACR_0161 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808202.1 147233 R 272622 CDS YP_808203.1 116510987 4432205 complement(148588..149025) 1 NC_008527.1 hypothetical protein 149025 4432205 LACR_0162 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808203.1 148588 R 272622 CDS YP_808204.1 116510988 4432206 149195..149947 1 NC_008527.1 DNA-entry nuclease 149947 4432206 LACR_0163 Lactococcus lactis subsp. cremoris SK11 DNA-entry nuclease YP_808204.1 149195 D 272622 CDS YP_808205.1 116510989 4432207 150126..150320 1 NC_008527.1 hypothetical protein 150320 4432207 LACR_0164 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808205.1 150126 D 272622 CDS YP_808206.1 116510990 4432208 150332..150571 1 NC_008527.1 hypothetical protein 150571 4432208 LACR_0165 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808206.1 150332 D 272622 CDS YP_808207.1 116510991 4434651 150769..152349 1 NC_008527.1 glycosyltransferase 152349 4434651 LACR_0166 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808207.1 150769 D 272622 CDS YP_808208.1 116510992 4434652 152479..153693 1 NC_008527.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 153693 4434652 LACR_0167 Lactococcus lactis subsp. cremoris SK11 aminotransferase AlaT YP_808208.1 152479 D 272622 CDS YP_808209.1 116510993 4434653 153846..154634 1 NC_008527.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 154634 4434653 LACR_0168 Lactococcus lactis subsp. cremoris SK11 transcriptional repressor CodY YP_808209.1 153846 D 272622 CDS YP_808210.1 116510994 4434654 154912..155217 1 NC_008527.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 155217 gatC 4434654 gatC Lactococcus lactis subsp. cremoris SK11 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_808210.1 154912 D 272622 CDS YP_808211.1 116510995 4434655 155217..156677 1 NC_008527.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 156677 gatA 4434655 gatA Lactococcus lactis subsp. cremoris SK11 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_808211.1 155217 D 272622 CDS YP_808212.1 116510996 4434656 156702..158135 1 NC_008527.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 158135 gatB 4434656 gatB Lactococcus lactis subsp. cremoris SK11 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_808212.1 156702 D 272622 CDS YP_808213.1 116510997 4434657 158259..159758 1 NC_008527.1 amidase 159758 4434657 LACR_0172 Lactococcus lactis subsp. cremoris SK11 amidase YP_808213.1 158259 D 272622 CDS YP_808214.1 116510998 4434658 complement(159824..161164) 1 NC_008527.1 Na+-driven multidrug efflux pump 161164 4434658 LACR_0173 Lactococcus lactis subsp. cremoris SK11 Na+-driven multidrug efflux pump YP_808214.1 159824 R 272622 CDS YP_808215.1 116510999 4434659 complement(161346..161543) 1 NC_008527.1 cold-shock DNA-binding protein family protein 161543 4434659 LACR_0174 Lactococcus lactis subsp. cremoris SK11 cold-shock DNA-binding protein family protein YP_808215.1 161346 R 272622 CDS YP_808216.1 116511000 4434661 162186..162878 1 NC_008527.1 membrane-associated serine protease 162878 4434661 LACR_0176 Lactococcus lactis subsp. cremoris SK11 membrane-associated serine protease YP_808216.1 162186 D 272622 CDS YP_808217.1 116511001 4434662 162977..163408 1 NC_008527.1 hypothetical protein 163408 4434662 LACR_0177 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808217.1 162977 D 272622 CDS YP_808218.1 116511002 4434663 163429..163809 1 NC_008527.1 lactoylglutathione lyase related lyase 163809 4434663 LACR_0178 Lactococcus lactis subsp. cremoris SK11 lactoylglutathione lyase related lyase YP_808218.1 163429 D 272622 CDS YP_808219.1 116511003 4434664 163920..164972 1 NC_008527.1 acetyltransferase 164972 4434664 LACR_0179 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808219.1 163920 D 272622 CDS YP_808220.1 116511004 4434665 165320..166411 1 NC_008527.1 hypothetical protein 166411 4434665 LACR_0180 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808220.1 165320 D 272622 CDS YP_808221.1 116511005 4434666 166511..167995 1 NC_008527.1 cellobiose-specific PTS system IIC component 167995 4434666 LACR_0181 Lactococcus lactis subsp. cremoris SK11 cellobiose-specific PTS system IIC component YP_808221.1 166511 D 272622 CDS YP_808222.1 116511006 4434667 168121..168327 1 NC_008527.1 hypothetical protein 168327 4434667 LACR_0182 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808222.1 168121 D 272622 CDS YP_808223.1 116511007 4434668 168324..168518 1 NC_008527.1 hypothetical protein 168518 4434668 LACR_0183 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808223.1 168324 D 272622 CDS YP_808224.1 116511008 4433874 168647..170083 1 NC_008527.1 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase 170083 4433874 LACR_0184 Lactococcus lactis subsp. cremoris SK11 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase YP_808224.1 168647 D 272622 CDS YP_808225.1 116511009 4433875 170149..170601 1 NC_008527.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 170601 dut 4433875 dut Lactococcus lactis subsp. cremoris SK11 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_808225.1 170149 D 272622 CDS YP_808226.1 116511010 4433876 170694..172034 1 NC_008527.1 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase 172034 4433876 LACR_0186 Lactococcus lactis subsp. cremoris SK11 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase YP_808226.1 170694 D 272622 CDS YP_808227.1 116511011 4433877 172049..172816 1 NC_008527.1 hypothetical protein 172816 4433877 LACR_0187 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808227.1 172049 D 272622 CDS YP_808228.1 116511012 4433878 173008..174105 1 NC_008527.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 174105 4433878 LACR_0188 Lactococcus lactis subsp. cremoris SK11 ribosomal RNA large subunit methyltransferase N YP_808228.1 173008 D 272622 CDS YP_808229.1 116511013 4433879 174353..174964 1 NC_008527.1 nitroreductase 174964 4433879 LACR_0189 Lactococcus lactis subsp. cremoris SK11 nitroreductase YP_808229.1 174353 D 272622 CDS YP_808230.1 116511014 4433880 175115..176095 1 NC_008527.1 prenyl transferase 176095 4433880 LACR_0190 Lactococcus lactis subsp. cremoris SK11 prenyl transferase YP_808230.1 175115 D 272622 CDS YP_808231.1 116511015 4433881 176291..177196 1 NC_008527.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 177196 4433881 LACR_0191 Lactococcus lactis subsp. cremoris SK11 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_808231.1 176291 D 272622 CDS YP_808232.1 116511016 4433882 complement(177257..177457) 1 NC_008527.1 hypothetical protein 177457 4433882 LACR_0192 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808232.1 177257 R 272622 CDS YP_808233.1 116511017 4433883 complement(177444..179519) 1 NC_008527.1 Fe2+ transport system protein B 179519 4433883 LACR_0193 Lactococcus lactis subsp. cremoris SK11 Fe2+ transport system protein B YP_808233.1 177444 R 272622 CDS YP_808234.1 116511018 4433884 complement(179622..180080) 1 NC_008527.1 Fe2+ transport system protein A 180080 4433884 LACR_0194 Lactococcus lactis subsp. cremoris SK11 Fe2+ transport system protein A YP_808234.1 179622 R 272622 CDS YP_808235.1 116511019 4433885 180411..180839 1 NC_008527.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 180839 4433885 LACR_0195 Lactococcus lactis subsp. cremoris SK11 methionine sulfoxide reductase B YP_808235.1 180411 D 272622 CDS YP_808236.1 116511020 4433886 complement(180967..182631) 1 NC_008527.1 dihydroxyacetone kinase-like protein 182631 4433886 LACR_0196 Lactococcus lactis subsp. cremoris SK11 dihydroxyacetone kinase-like protein YP_808236.1 180967 R 272622 CDS YP_808237.1 116511021 4433887 complement(182631..183065) 1 NC_008527.1 hypothetical protein 183065 4433887 LACR_0197 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808237.1 182631 R 272622 CDS YP_808238.1 116511022 4433888 complement(183272..183466) 1 NC_008527.1 required for 70S ribosome assembly; 50S ribosomal protein L28 183466 rpmB 4433888 rpmB Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L28 YP_808238.1 183272 R 272622 CDS YP_808239.1 116511023 4433889 183603..184262 1 NC_008527.1 hypothetical protein 184262 4433889 LACR_0199 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808239.1 183603 D 272622 CDS YP_808240.1 116511024 4433890 184457..185326 1 NC_008527.1 glucose-1-phosphate thymidylyltransferase 185326 4433890 LACR_0200 Lactococcus lactis subsp. cremoris SK11 glucose-1-phosphate thymidylyltransferase YP_808240.1 184457 D 272622 CDS YP_808241.1 116511025 4434528 185374..185496 1 NC_008527.1 hypothetical protein 185496 4434528 LACR_0201 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808241.1 185374 D 272622 CDS YP_808242.1 116511026 4434529 185725..186318 1 NC_008527.1 dTDP-4-keto-6-deoxyglucose-3,5-epimerase 186318 4434529 LACR_0202 Lactococcus lactis subsp. cremoris SK11 dTDP-4-keto-6-deoxyglucose-3,5-epimerase YP_808242.1 185725 D 272622 CDS YP_808243.1 116511027 4434530 186318..186572 1 NC_008527.1 hypothetical protein 186572 4434530 LACR_0203 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808243.1 186318 D 272622 CDS YP_808244.1 116511028 4434531 186614..187666 1 NC_008527.1 dTDP-glucose 4,6-dehydratase 187666 4434531 LACR_0204 Lactococcus lactis subsp. cremoris SK11 dTDP-glucose 4,6-dehydratase YP_808244.1 186614 D 272622 CDS YP_808245.1 116511029 4434532 187710..188651 1 NC_008527.1 dTDP-4-dehydrorhamnose reductase 188651 4434532 LACR_0205 Lactococcus lactis subsp. cremoris SK11 dTDP-4-dehydrorhamnose reductase YP_808245.1 187710 D 272622 CDS YP_808246.1 116511030 4434533 188785..189993 1 NC_008527.1 glycosyltransferase 189993 4434533 LACR_0206 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808246.1 188785 D 272622 CDS YP_808247.1 116511031 4434534 189983..190924 1 NC_008527.1 glycosyltransferase 190924 4434534 LACR_0207 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808247.1 189983 D 272622 CDS YP_808248.1 116511032 4434535 190921..191730 1 NC_008527.1 ABC-type polysaccharide/polyol phosphate export system, permease component 191730 4434535 LACR_0208 Lactococcus lactis subsp. cremoris SK11 ABC-type polysaccharide/polyol phosphate export system, permease component YP_808248.1 190921 D 272622 CDS YP_808249.1 116511033 4434536 191744..192937 1 NC_008527.1 ABC-type polysaccharide/polyol phosphate transport system, ATPase component 192937 4434536 LACR_0209 Lactococcus lactis subsp. cremoris SK11 ABC-type polysaccharide/polyol phosphate transport system, ATPase component YP_808249.1 191744 D 272622 CDS YP_808250.1 116511034 4434537 192930..194306 1 NC_008527.1 hypothetical protein 194306 4434537 LACR_0210 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808250.1 192930 D 272622 CDS YP_808251.1 116511035 4434538 194315..195280 1 NC_008527.1 glycosyltransferase 195280 4434538 LACR_0211 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808251.1 194315 D 272622 CDS YP_808252.1 116511036 4434539 195270..197036 1 NC_008527.1 lipopolysaccharide biosynthesis protein 197036 4434539 LACR_0212 Lactococcus lactis subsp. cremoris SK11 lipopolysaccharide biosynthesis protein YP_808252.1 195270 D 272622 CDS YP_808253.1 116511037 4434540 197113..197850 1 NC_008527.1 glycosyltransferase 197850 4434540 LACR_0213 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808253.1 197113 D 272622 CDS YP_808254.1 116511038 4434541 197850..198203 1 NC_008527.1 hypothetical protein 198203 4434541 LACR_0214 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808254.1 197850 D 272622 CDS YP_808255.1 116511039 4434542 198225..199364 1 NC_008527.1 glycosyltransferase 199364 4434542 LACR_0215 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808255.1 198225 D 272622 CDS YP_808256.1 116511040 4434543 199495..200487 1 NC_008527.1 glycosyltransferase 200487 4434543 LACR_0216 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808256.1 199495 D 272622 CDS YP_808257.1 116511041 4434544 200484..201581 1 NC_008527.1 glycosyltransferase 201581 4434544 LACR_0217 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808257.1 200484 D 272622 CDS YP_808258.1 116511042 4434545 201658..202695 1 NC_008527.1 hypothetical protein 202695 4434545 LACR_0218 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808258.1 201658 D 272622 CDS YP_808259.1 116511043 4434372 202688..203830 1 NC_008527.1 UDP-galactopyranose mutase 203830 4434372 LACR_0219 Lactococcus lactis subsp. cremoris SK11 UDP-galactopyranose mutase YP_808259.1 202688 D 272622 CDS YP_808260.1 116511044 4434373 203827..205245 1 NC_008527.1 PST family polysaccharide transporter 205245 4434373 LACR_0220 Lactococcus lactis subsp. cremoris SK11 PST family polysaccharide transporter YP_808260.1 203827 D 272622 CDS YP_808261.1 116511045 4434374 205274..207073 1 NC_008527.1 hypothetical protein 207073 4434374 LACR_0221 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808261.1 205274 D 272622 CDS YP_808262.1 116511046 4434375 207075..208496 1 NC_008527.1 hypothetical protein 208496 4434375 LACR_0222 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808262.1 207075 D 272622 CDS YP_808263.1 116511047 4434376 complement(208634..209257) 1 NC_008527.1 surface antigen 209257 4434376 LACR_0223 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_808263.1 208634 R 272622 CDS YP_808264.1 116511048 4434377 complement(209247..209966) 1 NC_008527.1 hypothetical protein 209966 4434377 LACR_0224 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808264.1 209247 R 272622 CDS YP_808265.1 116511049 4434378 210348..211829 1 NC_008527.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 211829 4434378 LACR_0225 Lactococcus lactis subsp. cremoris SK11 inosine 5'-monophosphate dehydrogenase YP_808265.1 210348 D 272622 CDS YP_808266.1 116511050 4434379 211995..213200 1 NC_008527.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 213200 4434379 LACR_0226 Lactococcus lactis subsp. cremoris SK11 GTP-binding protein YqeH YP_808266.1 211995 D 272622 CDS YP_808267.1 116511051 4434380 213295..213798 1 NC_008527.1 hypothetical protein 213798 4434380 LACR_0227 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808267.1 213295 D 272622 CDS YP_808268.1 116511052 4434381 213881..215125 1 NC_008527.1 GTPase 215125 4434381 LACR_0228 Lactococcus lactis subsp. cremoris SK11 GTPase YP_808268.1 213881 D 272622 CDS YP_808269.1 116511053 4434382 complement(215254..215580) 1 NC_008527.1 hypothetical protein 215580 4434382 LACR_0229 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808269.1 215254 R 272622 CDS YP_808270.1 116511054 4434383 215749..216063 1 NC_008527.1 RNA-binding protein 216063 4434383 LACR_0230 Lactococcus lactis subsp. cremoris SK11 RNA-binding protein YP_808270.1 215749 D 272622 CDS YP_808271.1 116511055 4434384 216138..216737 1 NC_008527.1 nicotinic acid mononucleotide adenylyltransferase 216737 4434384 LACR_0231 Lactococcus lactis subsp. cremoris SK11 nicotinic acid mononucleotide adenylyltransferase YP_808271.1 216138 D 272622 CDS YP_808272.1 116511056 4434385 216730..217320 1 NC_008527.1 HD superfamily hydrolase 217320 4434385 LACR_0232 Lactococcus lactis subsp. cremoris SK11 HD superfamily hydrolase YP_808272.1 216730 D 272622 CDS YP_808273.1 116511057 4434386 217367..217798 1 NC_008527.1 acetyltransferase 217798 4434386 LACR_0233 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808273.1 217367 D 272622 CDS YP_808274.1 116511058 4434387 217965..218324 1 NC_008527.1 hypothetical protein 218324 4434387 LACR_0234 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808274.1 217965 D 272622 CDS YP_808275.1 116511059 4434388 218328..219158 1 NC_008527.1 hypothetical protein 219158 4434388 LACR_0235 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808275.1 218328 D 272622 CDS YP_808276.1 116511060 4433786 219208..220377 1 NC_008527.1 hypothetical protein 220377 4433786 LACR_0236 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808276.1 219208 D 272622 CDS YP_808277.1 116511061 4433787 220530..221246 1 NC_008527.1 hypothetical protein 221246 4433787 LACR_0237 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808277.1 220530 D 272622 CDS YP_808278.1 116511062 4433788 221311..221952 1 NC_008527.1 hypothetical protein 221952 4433788 LACR_0238 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808278.1 221311 D 272622 CDS YP_808279.1 116511063 4433789 221949..222608 1 NC_008527.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 222608 4433789 LACR_0239 Lactococcus lactis subsp. cremoris SK11 uracil-DNA glycosylase YP_808279.1 221949 D 272622 CDS YP_808280.1 116511064 4433790 complement(222746..223555) 1 NC_008527.1 NADPH:quinone reductase related Zn-dependent oxidoreductase 223555 4433790 LACR_0240 Lactococcus lactis subsp. cremoris SK11 NADPH:quinone reductase related Zn-dependent oxidoreductase YP_808280.1 222746 R 272622 CDS YP_808281.1 116511065 4433791 complement(223578..224456) 1 NC_008527.1 nucleoside-diphosphate sugar epimerase 224456 4433791 LACR_0241 Lactococcus lactis subsp. cremoris SK11 nucleoside-diphosphate sugar epimerase YP_808281.1 223578 R 272622 CDS YP_808282.1 116511066 4433792 complement(224478..225317) 1 NC_008527.1 saccharopine dehydrogenase related protein 225317 4433792 LACR_0242 Lactococcus lactis subsp. cremoris SK11 saccharopine dehydrogenase related protein YP_808282.1 224478 R 272622 CDS YP_808283.1 116511067 4433793 225521..226066 1 NC_008527.1 transcriptional regulator 226066 4433793 LACR_0243 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808283.1 225521 D 272622 CDS YP_808284.1 116511068 4433794 complement(226179..227600) 1 NC_008527.1 major facilitator superfamily permease 227600 4433794 LACR_0244 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808284.1 226179 R 272622 CDS YP_808285.1 116511069 4433795 227827..228198 1 NC_008527.1 transcriptional regulator 228198 4433795 LACR_0245 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808285.1 227827 D 272622 CDS YP_808286.1 116511070 4433796 228279..228455 1 NC_008527.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 228455 rpsU 4433796 rpsU Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S21 YP_808286.1 228279 D 272622 CDS YP_808287.1 116511071 4433797 228563..229375 1 NC_008527.1 HAD superfamily hydrolase 229375 4433797 LACR_0247 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_808287.1 228563 D 272622 CDS YP_808288.1 116511072 4433798 229577..230773 1 NC_008527.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 230773 pgk 4433798 pgk Lactococcus lactis subsp. cremoris SK11 phosphoglycerate kinase YP_808288.1 229577 D 272622 CDS YP_808289.1 116511073 4433799 230831..231505 1 NC_008527.1 HAD superfamily hydrolase 231505 4433799 LACR_0249 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_808289.1 230831 D 272622 CDS YP_808290.1 116511074 4433800 231625..232611 1 NC_008527.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; DhaKLM operon coactivator DhaQ 232611 4433800 LACR_0250 Lactococcus lactis subsp. cremoris SK11 DhaKLM operon coactivator DhaQ YP_808290.1 231625 D 272622 CDS YP_808291.1 116511075 4433287 234833..235204 1 NC_008527.1 hypothetical protein 235204 4433287 LACR_0254 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808291.1 234833 D 272622 CDS YP_808292.1 116511076 4433288 235214..235930 1 NC_008527.1 glycerol uptake facilitator related permease (major Intrinsic protein family) 235930 4433288 LACR_0255 Lactococcus lactis subsp. cremoris SK11 glycerol uptake facilitator related permease (major Intrinsic protein family) YP_808292.1 235214 D 272622 CDS YP_808293.1 116511077 4433290 237590..238336 1 NC_008527.1 ABC-type multidrug transport system, ATPase component 238336 4433290 LACR_0257 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase component YP_808293.1 237590 D 272622 CDS YP_808294.1 116511078 4433291 238333..239475 1 NC_008527.1 ABC transporter permease 239475 4433291 LACR_0258 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease YP_808294.1 238333 D 272622 CDS YP_808295.1 116511079 4433292 239598..240767 1 NC_008527.1 SAM-dependent methyltransferase 240767 4433292 LACR_0259 Lactococcus lactis subsp. cremoris SK11 SAM-dependent methyltransferase YP_808295.1 239598 D 272622 CDS YP_808296.1 116511080 4433295 complement(243086..244360) 1 NC_008527.1 flavoprotein 244360 4433295 LACR_0262 Lactococcus lactis subsp. cremoris SK11 flavoprotein YP_808296.1 243086 R 272622 CDS YP_808297.1 116511081 4433296 244398..245225 1 NC_008527.1 sugar kinase 245225 4433296 LACR_0263 Lactococcus lactis subsp. cremoris SK11 sugar kinase YP_808297.1 244398 D 272622 CDS YP_808298.1 116511082 4433297 245299..245712 1 NC_008527.1 hypothetical protein 245712 4433297 LACR_0264 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808298.1 245299 D 272622 CDS YP_808299.1 116511083 4433298 245964..247745 1 NC_008527.1 ABC transporter ATP-binding protein 247745 4433298 LACR_0265 Lactococcus lactis subsp. cremoris SK11 ABC transporter ATP-binding protein YP_808299.1 245964 D 272622 CDS YP_808300.1 116511084 4433299 247742..249640 1 NC_008527.1 ABC-type multidrug transport system, ATPase and permease component 249640 4433299 LACR_0266 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase and permease component YP_808300.1 247742 D 272622 CDS YP_808301.1 116511085 4433300 249731..250396 1 NC_008527.1 GTPase domain-containing protein 250396 4433300 LACR_0267 Lactococcus lactis subsp. cremoris SK11 GTPase domain-containing protein YP_808301.1 249731 D 272622 CDS YP_808302.1 116511086 4433301 complement(250442..251461) 1 NC_008527.1 dehydrogenase related protein 251461 4433301 LACR_0268 Lactococcus lactis subsp. cremoris SK11 dehydrogenase related protein YP_808302.1 250442 R 272622 CDS YP_808303.1 116511087 4433302 complement(251445..251612) 1 NC_008527.1 hypothetical protein 251612 4433302 LACR_0269 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808303.1 251445 R 272622 CDS YP_808304.1 116511088 4434424 complement(251811..252287) 1 NC_008527.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 252287 4434424 LACR_0270 Lactococcus lactis subsp. cremoris SK11 S-ribosylhomocysteinase YP_808304.1 251811 R 272622 CDS YP_808305.1 116511089 4434425 252504..252968 1 NC_008527.1 hypothetical protein 252968 4434425 LACR_0271 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808305.1 252504 D 272622 CDS YP_808306.1 116511090 4434426 253035..253880 1 NC_008527.1 aldo/keto reductase 253880 4434426 LACR_0272 Lactococcus lactis subsp. cremoris SK11 aldo/keto reductase YP_808306.1 253035 D 272622 CDS YP_808307.1 116511091 4434427 254120..254632 1 NC_008527.1 amidase 254632 4434427 LACR_0273 Lactococcus lactis subsp. cremoris SK11 amidase YP_808307.1 254120 D 272622 CDS YP_808308.1 116511092 4434428 254729..255295 1 NC_008527.1 hypothetical protein 255295 4434428 LACR_0274 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808308.1 254729 D 272622 CDS YP_808309.1 116511093 4434429 255292..255576 1 NC_008527.1 hypothetical protein 255576 4434429 LACR_0275 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808309.1 255292 D 272622 CDS YP_808310.1 116511094 4434431 257283..259526 1 NC_008527.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 259526 4434431 LACR_0277 Lactococcus lactis subsp. cremoris SK11 anaerobic ribonucleoside triphosphate reductase YP_808310.1 257283 D 272622 CDS YP_808311.1 116511095 4434432 259529..260182 1 NC_008527.1 anaerobic ribonucleoside-triphosphate reductase activating protein 260182 4434432 LACR_0278 Lactococcus lactis subsp. cremoris SK11 anaerobic ribonucleoside-triphosphate reductase activating protein YP_808311.1 259529 D 272622 CDS YP_808312.1 116511096 4434433 complement(260254..260763) 1 NC_008527.1 hypothetical protein 260763 4434433 LACR_0279 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808312.1 260254 R 272622 CDS YP_808313.1 116511097 4434434 260967..261365 1 NC_008527.1 hypothetical protein 261365 4434434 LACR_0280 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808313.1 260967 D 272622 CDS YP_808314.1 116511098 4434435 261334..261927 1 NC_008527.1 phage phi-C31 gp36 major capsid-like protein 261927 4434435 LACR_0281 Lactococcus lactis subsp. cremoris SK11 phage phi-C31 gp36 major capsid-like protein YP_808314.1 261334 D 272622 CDS YP_808315.1 116511099 4434436 262153..262347 1 NC_008527.1 hypothetical protein 262347 4434436 LACR_0282 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808315.1 262153 D 272622 CDS YP_808316.1 116511100 4434437 262560..263816 1 NC_008527.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 263816 eno 4434437 eno Lactococcus lactis subsp. cremoris SK11 phosphopyruvate hydratase YP_808316.1 262560 D 272622 CDS YP_808317.1 116511101 4434438 complement(263918..264961) 1 NC_008527.1 hypothetical protein 264961 4434438 LACR_0284 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808317.1 263918 R 272622 CDS YP_808318.1 116511102 4434439 complement(265280..265387) 1 NC_008527.1 hypothetical protein 265387 4434439 LACR_0285 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808318.1 265280 R 272622 CDS YP_808319.1 116511103 4434440 265994..266884 1 NC_008527.1 transposase 266884 4434440 LACR_0286 Lactococcus lactis subsp. cremoris SK11 transposase YP_808319.1 265994 D 272622 CDS YP_808320.1 116511104 4433225 267176..268009 1 NC_008527.1 with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 268009 cbiO 4433225 cbiO Lactococcus lactis subsp. cremoris SK11 cobalt transporter ATP-binding subunit YP_808320.1 267176 D 272622 CDS YP_808321.1 116511105 4433226 268281..269147 1 NC_008527.1 with CbiNQ forms the ABC transporter for cobalt import; Lactococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 269147 cbiO 4433226 cbiO Lactococcus lactis subsp. cremoris SK11 cobalt transporter ATP-binding subunit YP_808321.1 268281 D 272622 CDS YP_808322.1 116511106 4433227 269147..269947 1 NC_008527.1 ABC-type cobalt transport system, permease component CbiQ related transporter 269947 4433227 LACR_0290 Lactococcus lactis subsp. cremoris SK11 ABC-type cobalt transport system, permease component CbiQ related transporter YP_808322.1 269147 D 272622 CDS YP_808323.1 116511107 4433228 269970..270584 1 NC_008527.1 hypothetical protein 270584 4433228 LACR_0291 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808323.1 269970 D 272622 CDS YP_808324.1 116511108 4433229 270708..272012 1 NC_008527.1 hypothetical protein 272012 4433229 LACR_0292 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808324.1 270708 D 272622 CDS YP_808325.1 116511109 4433230 272069..272842 1 NC_008527.1 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 272842 4433230 LACR_0293 Lactococcus lactis subsp. cremoris SK11 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_808325.1 272069 D 272622 CDS YP_808326.1 116511110 4433231 272980..274110 1 NC_008527.1 metal-dependent amidase/aminoacylase/carboxypeptidase 274110 4433231 LACR_0294 Lactococcus lactis subsp. cremoris SK11 metal-dependent amidase/aminoacylase/carboxypeptidase YP_808326.1 272980 D 272622 CDS YP_808327.1 116511111 4433232 274267..275388 1 NC_008527.1 endo-1,4-beta-xylanase D 275388 4433232 LACR_0295 Lactococcus lactis subsp. cremoris SK11 endo-1,4-beta-xylanase D YP_808327.1 274267 D 272622 CDS YP_808328.1 116511112 4433235 275888..276010 1 NC_008527.1 hypothetical protein 276010 4433235 LACR_0298 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808328.1 275888 D 272622 CDS YP_808329.1 116511113 4433236 276137..277561 1 NC_008527.1 hypothetical protein 277561 4433236 LACR_0299 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808329.1 276137 D 272622 CDS YP_808330.1 116511114 4433237 277772..278383 1 NC_008527.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 278383 rpsD 4433237 rpsD Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S4 YP_808330.1 277772 D 272622 CDS YP_808331.1 116511115 4433238 complement(278489..279685) 1 NC_008527.1 integrase 279685 4433238 LACR_0301 Lactococcus lactis subsp. cremoris SK11 integrase YP_808331.1 278489 R 272622 CDS YP_808332.1 116511116 4434564 complement(279778..280455) 1 NC_008527.1 transcriptional regulator 280455 4434564 LACR_0302 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808332.1 279778 R 272622 CDS YP_808333.1 116511117 4434565 280611..280841 1 NC_008527.1 transcriptional regulator 280841 4434565 LACR_0303 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808333.1 280611 D 272622 CDS YP_808334.1 116511118 4434566 281058..281726 1 NC_008527.1 phage-encoded protein 281726 4434566 LACR_0304 Lactococcus lactis subsp. cremoris SK11 phage-encoded protein YP_808334.1 281058 D 272622 CDS YP_808335.1 116511119 4434567 281825..281995 1 NC_008527.1 hypothetical protein 281995 4434567 LACR_0305 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808335.1 281825 D 272622 CDS YP_808336.1 116511120 4434568 281997..282251 1 NC_008527.1 hypothetical protein 282251 4434568 LACR_0306 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808336.1 281997 D 272622 CDS YP_808337.1 116511121 4434569 282248..282400 1 NC_008527.1 hypothetical protein 282400 4434569 LACR_0307 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808337.1 282248 D 272622 CDS YP_808338.1 116511122 4434570 282397..282666 1 NC_008527.1 hypothetical protein 282666 4434570 LACR_0308 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808338.1 282397 D 272622 CDS YP_808339.1 116511123 4434571 282677..284374 1 NC_008527.1 hypothetical protein 284374 4434571 LACR_0309 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808339.1 282677 D 272622 CDS YP_808340.1 116511124 4434572 284736..284918 1 NC_008527.1 hypothetical protein 284918 4434572 LACR_0310 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808340.1 284736 D 272622 CDS YP_808341.1 116511125 4434573 284937..285143 1 NC_008527.1 hypothetical protein 285143 4434573 LACR_0311 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808341.1 284937 D 272622 CDS YP_808342.1 116511126 4434574 285305..285877 1 NC_008527.1 hypothetical protein 285877 4434574 LACR_0312 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808342.1 285305 D 272622 CDS YP_808343.1 116511127 4434575 285893..286255 1 NC_008527.1 hypothetical protein 286255 4434575 LACR_0313 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808343.1 285893 D 272622 CDS YP_808344.1 116511128 4434576 286437..286607 1 NC_008527.1 hypothetical protein 286607 4434576 LACR_0314 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808344.1 286437 D 272622 CDS YP_808345.1 116511129 4434577 286809..287039 1 NC_008527.1 hypothetical protein 287039 4434577 LACR_0315 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808345.1 286809 D 272622 CDS YP_808346.1 116511130 4434578 287199..288398 1 NC_008527.1 hypothetical protein 288398 4434578 LACR_0316 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808346.1 287199 D 272622 CDS YP_808347.1 116511131 4434579 288398..288913 1 NC_008527.1 hypothetical protein 288913 4434579 LACR_0317 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808347.1 288398 D 272622 CDS YP_808348.1 116511132 4434580 288996..289370 1 NC_008527.1 hypothetical protein 289370 4434580 LACR_0318 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808348.1 288996 D 272622 CDS YP_808349.1 116511133 4434581 289695..291836 1 NC_008527.1 transcriptional accessory protein 291836 4434581 LACR_0319 Lactococcus lactis subsp. cremoris SK11 transcriptional accessory protein YP_808349.1 289695 D 272622 CDS YP_808350.1 116511134 4434407 291969..292412 1 NC_008527.1 hypothetical protein 292412 4434407 LACR_0320 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808350.1 291969 D 272622 CDS YP_808351.1 116511135 4434408 292713..293747 1 NC_008527.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 293747 4434408 LACR_0321 Lactococcus lactis subsp. cremoris SK11 adenosine deaminase YP_808351.1 292713 D 272622 CDS YP_808352.1 116511136 4434409 complement(293811..294200) 1 NC_008527.1 hypothetical protein 294200 4434409 LACR_0322 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808352.1 293811 R 272622 CDS YP_808353.1 116511137 4434410 complement(294236..294589) 1 NC_008527.1 transcriptional regulator 294589 4434410 LACR_0323 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808353.1 294236 R 272622 CDS YP_808354.1 116511138 4434411 complement(294757..296442) 1 NC_008527.1 mRNA degradation ribonuclease J1/J2enzyme 296442 4434411 LACR_0324 Lactococcus lactis subsp. cremoris SK11 mRNA degradation ribonuclease J1/J2enzyme YP_808354.1 294757 R 272622 CDS YP_808355.2 229269518 4434412 complement(296636..296866) 1 NC_008527.1 hypothetical protein 296866 4434412 LACR_0325 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808355.2 296636 R 272622 CDS YP_808356.1 116511140 4434413 296971..297108 1 NC_008527.1 hypothetical protein 297108 4434413 LACR_0326 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808356.1 296971 D 272622 CDS YP_808357.1 116511141 4434414 297204..297929 1 NC_008527.1 metal-dependent protease related protein, putative molecular chaperone 297929 4434414 LACR_0327 Lactococcus lactis subsp. cremoris SK11 metal-dependent protease related protein, putative molecular chaperone YP_808357.1 297204 D 272622 CDS YP_808358.1 116511142 4434415 297883..298452 1 NC_008527.1 SSU ribosomal protein S18P alanine acetyltransferase 298452 4434415 LACR_0328 Lactococcus lactis subsp. cremoris SK11 SSU ribosomal protein S18P alanine acetyltransferase YP_808358.1 297883 D 272622 CDS YP_808359.1 116511143 4434416 298449..298919 1 NC_008527.1 acetyltransferase 298919 4434416 LACR_0329 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808359.1 298449 D 272622 CDS YP_808360.1 116511144 4434417 298922..299947 1 NC_008527.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 299947 4434417 LACR_0330 Lactococcus lactis subsp. cremoris SK11 putative DNA-binding/iron metalloprotein/AP endonuclease YP_808360.1 298922 D 272622 CDS YP_808361.1 116511145 4434418 299962..300162 1 NC_008527.1 hypothetical protein 300162 4434418 LACR_0331 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808361.1 299962 D 272622 CDS YP_808362.1 116511146 4434419 complement(300331..300492) 1 NC_008527.1 hypothetical protein 300492 4434419 LACR_0332 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808362.1 300331 R 272622 CDS YP_808363.1 116511147 4434420 complement(300596..301387) 1 NC_008527.1 hypothetical protein 301387 4434420 LACR_0333 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808363.1 300596 R 272622 CDS YP_808364.1 116511148 4434422 302851..303591 1 NC_008527.1 ABC-type phosphate/phosphonate transport system, ATPase component 303591 4434422 LACR_0335 Lactococcus lactis subsp. cremoris SK11 ABC-type phosphate/phosphonate transport system, ATPase component YP_808364.1 302851 D 272622 CDS YP_808365.1 116511149 4434423 303592..304404 1 NC_008527.1 ABC-type phosphate/phosphonate transport system, permease component 304404 4434423 LACR_0336 Lactococcus lactis subsp. cremoris SK11 ABC-type phosphate/phosphonate transport system, permease component YP_808365.1 303592 D 272622 CDS YP_808366.1 116511150 4434169 304424..305233 1 NC_008527.1 ABC-type phosphate/phosphonate transport system, permease component 305233 4434169 LACR_0337 Lactococcus lactis subsp. cremoris SK11 ABC-type phosphate/phosphonate transport system, permease component YP_808366.1 304424 D 272622 CDS YP_808367.1 116511151 4434170 305240..306799 1 NC_008527.1 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase 306799 4434170 LACR_0338 Lactococcus lactis subsp. cremoris SK11 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase YP_808367.1 305240 D 272622 CDS YP_808368.1 116511152 4434171 306943..307062 1 NC_008527.1 hypothetical protein 307062 4434171 LACR_0339 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808368.1 306943 D 272622 CDS YP_808369.1 116511153 4434172 307125..307607 1 NC_008527.1 thiol peroxidase 307607 4434172 LACR_0340 Lactococcus lactis subsp. cremoris SK11 thiol peroxidase YP_808369.1 307125 D 272622 CDS YP_808370.1 116511154 4434173 307776..310316 1 NC_008527.1 lysyl aminopeptidase 310316 4434173 LACR_0341 Lactococcus lactis subsp. cremoris SK11 lysyl aminopeptidase YP_808370.1 307776 D 272622 CDS YP_808371.1 116511155 4434174 complement(310364..311554) 1 NC_008527.1 major facilitator superfamily permease 311554 4434174 LACR_0342 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808371.1 310364 R 272622 CDS YP_808372.1 116511156 4434175 complement(312036..312509) 1 NC_008527.1 MarR family transcriptional regulator 312509 4434175 LACR_0343 Lactococcus lactis subsp. cremoris SK11 MarR family transcriptional regulator YP_808372.1 312036 R 272622 CDS YP_808373.1 116511157 4434176 complement(312506..313789) 1 NC_008527.1 cation transporter 313789 4434176 LACR_0344 Lactococcus lactis subsp. cremoris SK11 cation transporter YP_808373.1 312506 R 272622 CDS YP_808374.1 116511158 4434177 314065..314415 1 NC_008527.1 PadR family transcriptional regulator 314415 4434177 LACR_0345 Lactococcus lactis subsp. cremoris SK11 PadR family transcriptional regulator YP_808374.1 314065 D 272622 CDS YP_808375.1 116511159 4434178 314712..316451 1 NC_008527.1 ABC-type multidrug transport system, ATPase and permease component 316451 4434178 LACR_0346 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase and permease component YP_808375.1 314712 D 272622 CDS YP_808376.1 116511160 4434179 316455..318449 1 NC_008527.1 ABC-type multidrug transport system, ATPase and permease component 318449 4434179 LACR_0347 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase and permease component YP_808376.1 316455 D 272622 CDS YP_808377.1 116511161 4434180 318623..319888 1 NC_008527.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 319888 4434180 LACR_0348 Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_808377.1 318623 D 272622 CDS YP_808378.1 116511162 4434181 319934..320152 1 NC_008527.1 hypothetical protein 320152 4434181 LACR_0349 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808378.1 319934 D 272622 CDS YP_808379.1 116511163 4434182 complement(320411..321301) 1 NC_008527.1 transposase 321301 4434182 LACR_0350 Lactococcus lactis subsp. cremoris SK11 transposase YP_808379.1 320411 R 272622 CDS YP_808380.1 116511164 4434183 321413..321490 1 NC_008527.1 hypothetical protein 321490 4434183 LACR_0351 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808380.1 321413 D 272622 CDS YP_808381.1 116511165 4434184 321546..321806 1 NC_008527.1 transposase 321806 4434184 LACR_0352 Lactococcus lactis subsp. cremoris SK11 transposase YP_808381.1 321546 D 272622 CDS YP_808382.1 116511166 4434185 322237..322647 1 NC_008527.1 transposase 322647 4434185 LACR_0353 Lactococcus lactis subsp. cremoris SK11 transposase YP_808382.1 322237 D 272622 CDS YP_808383.1 116511167 4434186 322765..323718 1 NC_008527.1 molybdopterin/thiamine biosynthesis dinucleotide-utilizing protein 323718 4434186 LACR_0354 Lactococcus lactis subsp. cremoris SK11 molybdopterin/thiamine biosynthesis dinucleotide-utilizing protein YP_808383.1 322765 D 272622 CDS YP_808384.1 116511168 4434152 323774..325009 1 NC_008527.1 major facilitator superfamily permease 325009 4434152 LACR_0355 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808384.1 323774 D 272622 CDS YP_808385.1 116511169 4434153 complement(325240..325578) 1 NC_008527.1 hypothetical protein 325578 4434153 LACR_0356 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808385.1 325240 R 272622 CDS YP_808386.1 116511170 4434154 complement(325620..326168) 1 NC_008527.1 hypothetical protein 326168 4434154 LACR_0357 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808386.1 325620 R 272622 CDS YP_808387.1 116511171 4434155 complement(326280..326756) 1 NC_008527.1 transcriptional regulator 326756 4434155 LACR_0358 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808387.1 326280 R 272622 CDS YP_808388.1 116511172 4434156 complement(326819..327367) 1 NC_008527.1 hypothetical protein 327367 4434156 LACR_0359 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808388.1 326819 R 272622 CDS YP_808389.1 116511173 4434157 328059..328961 1 NC_008527.1 ABC-type metal ion transport system, periplasmic component/surface antigen 328961 4434157 LACR_0360 Lactococcus lactis subsp. cremoris SK11 ABC-type metal ion transport system, periplasmic component/surface antigen YP_808389.1 328059 D 272622 CDS YP_808390.1 116511174 4434158 329106..329966 1 NC_008527.1 ABC-type metal ion transport system, periplasmic component/surface antigen 329966 4434158 LACR_0361 Lactococcus lactis subsp. cremoris SK11 ABC-type metal ion transport system, periplasmic component/surface antigen YP_808390.1 329106 D 272622 CDS YP_808391.1 116511175 4434159 330112..330975 1 NC_008527.1 ABC-type metal ion transport system, periplasmic component/surface antigen 330975 4434159 LACR_0362 Lactococcus lactis subsp. cremoris SK11 ABC-type metal ion transport system, periplasmic component/surface antigen YP_808391.1 330112 D 272622 CDS YP_808392.1 116511176 4434160 331044..331742 1 NC_008527.1 acetoin reductase 331742 4434160 LACR_0363 Lactococcus lactis subsp. cremoris SK11 acetoin reductase YP_808392.1 331044 D 272622 CDS YP_808393.1 116511177 4434161 331830..332690 1 NC_008527.1 ABC-type metal ion transport system, periplasmic component/surface antigen 332690 4434161 LACR_0364 Lactococcus lactis subsp. cremoris SK11 ABC-type metal ion transport system, periplasmic component/surface antigen YP_808393.1 331830 D 272622 CDS YP_808394.1 116511178 4434162 332814..333920 1 NC_008527.1 amino acid ABC transporter ATP-binding protein 333920 4434162 LACR_0365 Lactococcus lactis subsp. cremoris SK11 amino acid ABC transporter ATP-binding protein YP_808394.1 332814 D 272622 CDS YP_808395.1 116511179 4434163 333920..334615 1 NC_008527.1 ABC-type metal ion transport system, permease component 334615 4434163 LACR_0366 Lactococcus lactis subsp. cremoris SK11 ABC-type metal ion transport system, permease component YP_808395.1 333920 D 272622 CDS YP_808396.1 116511180 4434164 334640..335206 1 NC_008527.1 hypothetical protein 335206 4434164 LACR_0367 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808396.1 334640 D 272622 CDS YP_808397.1 116511181 4434165 335325..336950 1 NC_008527.1 ABC-type cobalt transport system, ATPase component 336950 4434165 LACR_0368 Lactococcus lactis subsp. cremoris SK11 ABC-type cobalt transport system, ATPase component YP_808397.1 335325 D 272622 CDS YP_808398.1 116511182 4434166 336997..337818 1 NC_008527.1 ABC-type cobalt transport system, permease component CbiQ related transporter 337818 4434166 LACR_0369 Lactococcus lactis subsp. cremoris SK11 ABC-type cobalt transport system, permease component CbiQ related transporter YP_808398.1 336997 D 272622 CDS YP_808399.1 116511183 4434167 338130..338423 1 NC_008527.1 transcriptional regulator 338423 4434167 LACR_0370 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808399.1 338130 D 272622 CDS YP_808400.1 116511184 4434168 338398..339126 1 NC_008527.1 ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component 339126 4434168 LACR_0371 Lactococcus lactis subsp. cremoris SK11 ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component YP_808400.1 338398 D 272622 CDS YP_808401.1 116511185 4433804 339119..340069 1 NC_008527.1 ferrichrome ABC transporter permease 340069 4433804 LACR_0372 Lactococcus lactis subsp. cremoris SK11 ferrichrome ABC transporter permease YP_808401.1 339119 D 272622 CDS YP_808402.1 116511186 4433805 340070..341008 1 NC_008527.1 ferrichrome ABC transporter permease 341008 4433805 LACR_0373 Lactococcus lactis subsp. cremoris SK11 ferrichrome ABC transporter permease YP_808402.1 340070 D 272622 CDS YP_808403.1 116511187 4433806 341092..342033 1 NC_008527.1 ferrichrome ABC transporter substrate-binding protein 342033 4433806 LACR_0374 Lactococcus lactis subsp. cremoris SK11 ferrichrome ABC transporter substrate-binding protein YP_808403.1 341092 D 272622 CDS YP_808404.1 116511188 4433807 342095..343000 1 NC_008527.1 LysR family transcriptional regulator 343000 4433807 LACR_0375 Lactococcus lactis subsp. cremoris SK11 LysR family transcriptional regulator YP_808404.1 342095 D 272622 CDS YP_808405.1 116511189 4433808 complement(343072..343962) 1 NC_008527.1 transposase 343962 4433808 LACR_0376 Lactococcus lactis subsp. cremoris SK11 transposase YP_808405.1 343072 R 272622 CDS YP_808406.1 116511190 4433809 complement(344070..345245) 1 NC_008527.1 arabinose efflux permease 345245 4433809 LACR_0377 Lactococcus lactis subsp. cremoris SK11 arabinose efflux permease YP_808406.1 344070 R 272622 CDS YP_808407.1 116511191 4433810 complement(345258..346076) 1 NC_008527.1 aldo/keto reductase 346076 4433810 LACR_0378 Lactococcus lactis subsp. cremoris SK11 aldo/keto reductase YP_808407.1 345258 R 272622 CDS YP_808408.1 116511192 4433811 346218..346565 1 NC_008527.1 transcriptional regulator 346565 4433811 LACR_0379 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808408.1 346218 D 272622 CDS YP_808409.1 116511193 4433812 346609..347001 1 NC_008527.1 lactoylglutathione lyase related lyase 347001 4433812 LACR_0380 Lactococcus lactis subsp. cremoris SK11 lactoylglutathione lyase related lyase YP_808409.1 346609 D 272622 CDS YP_808410.1 116511194 4433813 346994..347065 1 NC_008527.1 hypothetical protein 347065 4433813 LACR_0381 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808410.1 346994 D 272622 CDS YP_808411.1 116511195 4433814 347180..347881 1 NC_008527.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 347881 gpmA 4433814 gpmA Lactococcus lactis subsp. cremoris SK11 phosphoglyceromutase YP_808411.1 347180 D 272622 CDS YP_808412.1 116511196 4433815 348059..348622 1 NC_008527.1 peroxiredoxin 348622 4433815 LACR_0383 Lactococcus lactis subsp. cremoris SK11 peroxiredoxin YP_808412.1 348059 D 272622 CDS YP_808413.1 116511197 4433816 348688..350214 1 NC_008527.1 Alkyl hydroperoxide reductase, large subunit 350214 4433816 LACR_0384 Lactococcus lactis subsp. cremoris SK11 Alkyl hydroperoxide reductase, large subunit YP_808413.1 348688 D 272622 CDS YP_808414.1 116511198 4433817 350409..352571 1 NC_008527.1 penicillin-binding protein 2B 352571 4433817 LACR_0385 Lactococcus lactis subsp. cremoris SK11 penicillin-binding protein 2B YP_808414.1 350409 D 272622 CDS YP_808415.1 116511199 4433818 352701..353297 1 NC_008527.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 353297 recR 4433818 recR Lactococcus lactis subsp. cremoris SK11 recombination protein RecR YP_808415.1 352701 D 272622 CDS YP_808416.1 116511200 4433819 353362..354465 1 NC_008527.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 354465 ddl 4433819 ddl Lactococcus lactis subsp. cremoris SK11 D-alanyl-alanine synthetase A YP_808416.1 353362 D 272622 CDS YP_808417.1 116511201 4433820 354729..356051 1 NC_008527.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 356051 4433820 LACR_0388 Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_808417.1 354729 D 272622 CDS YP_808418.1 116511202 4433821 356220..357872 1 NC_008527.1 ABC-type oligopeptide transport system, periplasmic component 357872 4433821 LACR_0389 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, periplasmic component YP_808418.1 356220 D 272622 CDS YP_808419.1 116511203 4433839 358182..359819 1 NC_008527.1 ABC-type oligopeptide transport system, periplasmic component 359819 4433839 LACR_0390 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, periplasmic component YP_808419.1 358182 D 272622 CDS YP_808420.1 116511204 4433840 359898..360809 1 NC_008527.1 ABC-type dipeptide/oligopeptide/nickel transport system, permease component 360809 4433840 LACR_0391 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, permease component YP_808420.1 359898 D 272622 CDS YP_808421.1 116511205 4433841 360825..361856 1 NC_008527.1 ABC-type dipeptide/oligopeptide/nickel transport system, permease component 361856 4433841 LACR_0392 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, permease component YP_808421.1 360825 D 272622 CDS YP_808422.1 116511206 4433842 361859..362908 1 NC_008527.1 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component 362908 4433842 LACR_0393 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_808422.1 361859 D 272622 CDS YP_808423.1 116511207 4433843 362908..363846 1 NC_008527.1 ABC-type oligopeptide transport system, ATPase component 363846 4433843 LACR_0394 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, ATPase component YP_808423.1 362908 D 272622 CDS YP_808424.1 116511208 4433844 364240..365811 1 NC_008527.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 365811 prfC 4433844 prfC Lactococcus lactis subsp. cremoris SK11 peptide chain release factor 3 YP_808424.1 364240 D 272622 CDS YP_808425.1 116511209 4433845 366134..367789 1 NC_008527.1 superfamily II DNA/RNA helicase 367789 4433845 LACR_0396 Lactococcus lactis subsp. cremoris SK11 superfamily II DNA/RNA helicase YP_808425.1 366134 D 272622 CDS YP_808426.1 116511210 4433846 368487..369398 1 NC_008527.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 369398 era 4433846 era Lactococcus lactis subsp. cremoris SK11 GTP-binding protein Era YP_808426.1 368487 D 272622 CDS YP_808427.1 116511211 4433847 369496..371088 1 NC_008527.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 371088 asnB 4433847 asnB Lactococcus lactis subsp. cremoris SK11 asparagine synthetase B YP_808427.1 369496 D 272622 CDS YP_808428.1 116511212 4433848 371279..372097 1 NC_008527.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 372097 4433848 LACR_0399 Lactococcus lactis subsp. cremoris SK11 formamidopyrimidine-DNA glycosylase YP_808428.1 371279 D 272622 CDS YP_808429.1 116511213 4433849 372250..373413 1 NC_008527.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 373413 recA 4433849 recA Lactococcus lactis subsp. cremoris SK11 recombinase A YP_808429.1 372250 D 272622 CDS YP_808430.1 116511214 4433850 complement(373428..374810) 1 NC_008527.1 gamma-aminobutyrate permease related permease 374810 4433850 LACR_0401 Lactococcus lactis subsp. cremoris SK11 gamma-aminobutyrate permease related permease YP_808430.1 373428 R 272622 CDS YP_808431.1 116511215 4433851 complement(374882..376261) 1 NC_008527.1 gamma-aminobutyrate permease related permease 376261 4433851 LACR_0402 Lactococcus lactis subsp. cremoris SK11 gamma-aminobutyrate permease related permease YP_808431.1 374882 R 272622 CDS YP_808432.1 116511216 4433852 376408..376788 1 NC_008527.1 hypothetical protein 376788 4433852 LACR_0403 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808432.1 376408 D 272622 CDS YP_808433.1 116511217 4433853 376775..377086 1 NC_008527.1 hypothetical protein 377086 4433853 LACR_0404 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808433.1 376775 D 272622 CDS YP_808434.1 116511218 4433854 377104..377829 1 NC_008527.1 hypothetical protein 377829 4433854 LACR_0405 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808434.1 377104 D 272622 CDS YP_808435.1 116511219 4433855 complement(377893..378450) 1 NC_008527.1 hypothetical protein 378450 4433855 LACR_0406 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808435.1 377893 R 272622 CDS YP_808436.1 116511220 4433342 378733..379512 1 NC_008527.1 hypothetical protein 379512 4433342 LACR_0407 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808436.1 378733 D 272622 CDS YP_808437.1 116511221 4433343 379679..380359 1 NC_008527.1 RelA_SpoT domain-containing protein 380359 4433343 LACR_0408 Lactococcus lactis subsp. cremoris SK11 RelA_SpoT domain-containing protein YP_808437.1 379679 D 272622 CDS YP_808438.1 116511222 4433344 380346..381158 1 NC_008527.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 381158 ppnK 4433344 ppnK Lactococcus lactis subsp. cremoris SK11 inorganic polyphosphate/ATP-NAD kinase YP_808438.1 380346 D 272622 CDS YP_808439.1 116511223 4433345 381158..382039 1 NC_008527.1 pseudouridylate synthase, 23S RNA-specific 382039 4433345 LACR_0410 Lactococcus lactis subsp. cremoris SK11 pseudouridylate synthase, 23S RNA-specific YP_808439.1 381158 D 272622 CDS YP_808440.1 116511224 4433346 complement(382083..382916) 1 NC_008527.1 peptidyl-prolyl cis-trans isomerase 382916 4433346 LACR_0411 Lactococcus lactis subsp. cremoris SK11 peptidyl-prolyl cis-trans isomerase YP_808440.1 382083 R 272622 CDS YP_808441.1 116511225 4433347 383226..384659 1 NC_008527.1 amino acid transporter 384659 4433347 LACR_0412 Lactococcus lactis subsp. cremoris SK11 amino acid transporter YP_808441.1 383226 D 272622 CDS YP_808442.1 116511226 4433348 384819..385622 1 NC_008527.1 hypothetical protein 385622 4433348 LACR_0413 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808442.1 384819 D 272622 CDS YP_808443.1 116511227 4433349 385619..386596 1 NC_008527.1 membrane-associated lipoprotein for thiamine biosynthesis 386596 4433349 LACR_0414 Lactococcus lactis subsp. cremoris SK11 membrane-associated lipoprotein for thiamine biosynthesis YP_808443.1 385619 D 272622 CDS YP_808444.1 116511228 4433350 386720..387277 1 NC_008527.1 transposase 387277 4433350 LACR_0415 Lactococcus lactis subsp. cremoris SK11 transposase YP_808444.1 386720 D 272622 CDS YP_808445.1 116511229 4433351 387274..388092 1 NC_008527.1 transposase 388092 4433351 LACR_0416 Lactococcus lactis subsp. cremoris SK11 transposase YP_808445.1 387274 D 272622 CDS YP_808446.1 116511230 4433352 complement(388168..389652) 1 NC_008527.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 389652 lysS 4433352 lysS Lactococcus lactis subsp. cremoris SK11 lysyl-tRNA synthetase YP_808446.1 388168 R 272622 CDS YP_808447.1 116511231 4433354 390788..391828 1 NC_008527.1 hypothetical protein 391828 4433354 LACR_0419 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808447.1 390788 D 272622 CDS YP_808448.1 116511232 4433355 complement(391936..392010) 1 NC_008527.1 hypothetical protein 392010 4433355 LACR_0420 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808448.1 391936 R 272622 CDS YP_808449.1 116511233 4433356 complement(392046..392990) 1 NC_008527.1 L-lactate dehydrogenase 392990 4433356 LACR_0421 Lactococcus lactis subsp. cremoris SK11 L-lactate dehydrogenase YP_808449.1 392046 R 272622 CDS YP_808450.1 116511234 4433357 complement(393305..394126) 1 NC_008527.1 transcriptional regulator 394126 4433357 LACR_0422 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808450.1 393305 R 272622 CDS YP_808451.1 116511235 4433358 complement(394236..395126) 1 NC_008527.1 transposase 395126 4433358 LACR_0423 Lactococcus lactis subsp. cremoris SK11 transposase YP_808451.1 394236 R 272622 CDS YP_808452.1 116511236 4433359 395420..396262 1 NC_008527.1 tellurite resistance protein related permease 396262 4433359 LACR_0424 Lactococcus lactis subsp. cremoris SK11 tellurite resistance protein related permease YP_808452.1 395420 D 272622 CDS YP_808453.1 116511237 4433091 399620..400225 1 NC_008527.1 Acyl carrier protein phosphodiesterase 400225 4433091 LACR_0427 Lactococcus lactis subsp. cremoris SK11 Acyl carrier protein phosphodiesterase YP_808453.1 399620 D 272622 CDS YP_808454.1 116511238 4433092 400323..400757 1 NC_008527.1 hypothetical protein 400757 4433092 LACR_0428 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808454.1 400323 D 272622 CDS YP_808455.1 116511239 4433093 complement(400813..402855) 1 NC_008527.1 Na+/H+ antiporter 402855 4433093 LACR_0429 Lactococcus lactis subsp. cremoris SK11 Na+/H+ antiporter YP_808455.1 400813 R 272622 CDS YP_808456.1 116511240 4433094 complement(402945..403415) 1 NC_008527.1 hypothetical protein 403415 4433094 LACR_0430 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808456.1 402945 R 272622 CDS YP_808457.1 116511241 4433095 complement(403540..404799) 1 NC_008527.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 404799 4433095 LACR_0431 Lactococcus lactis subsp. cremoris SK11 tyrosyl-tRNA synthetase YP_808457.1 403540 R 272622 CDS YP_808458.1 116511242 4433096 404944..407382 1 NC_008527.1 membrane carboxypeptidase (penicillin-binding protein) 407382 4433096 LACR_0432 Lactococcus lactis subsp. cremoris SK11 membrane carboxypeptidase (penicillin-binding protein) YP_808458.1 404944 D 272622 CDS YP_808459.1 116511243 4433097 complement(407421..408488) 1 NC_008527.1 glutamyl aminopeptidase 408488 4433097 LACR_0433 Lactococcus lactis subsp. cremoris SK11 glutamyl aminopeptidase YP_808459.1 407421 R 272622 CDS YP_808460.1 116511244 4433098 408591..408875 1 NC_008527.1 hypothetical protein 408875 4433098 LACR_0434 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808460.1 408591 D 272622 CDS YP_808461.1 116511245 4433099 408920..409237 1 NC_008527.1 Thiol-disulfide isomerase and thioredoxin 409237 4433099 LACR_0435 Lactococcus lactis subsp. cremoris SK11 Thiol-disulfide isomerase and thioredoxin YP_808461.1 408920 D 272622 CDS YP_808462.1 116511246 4433100 409343..409969 1 NC_008527.1 EMAP domain-containing protein 409969 4433100 LACR_0436 Lactococcus lactis subsp. cremoris SK11 EMAP domain-containing protein YP_808462.1 409343 D 272622 CDS YP_808463.1 116511247 4433101 410131..411471 1 NC_008527.1 NADH oxidase 411471 4433101 LACR_0437 Lactococcus lactis subsp. cremoris SK11 NADH oxidase YP_808463.1 410131 D 272622 CDS YP_808464.1 116511248 4433102 411562..411951 1 NC_008527.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 411951 4433102 LACR_0438 Lactococcus lactis subsp. cremoris SK11 single-stranded DNA-binding protein YP_808464.1 411562 D 272622 CDS YP_808465.1 116511249 4433103 412070..412354 1 NC_008527.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 412354 groES 4433103 groES Lactococcus lactis subsp. cremoris SK11 co-chaperonin GroES YP_808465.1 412070 D 272622 CDS YP_808466.1 116511250 4433104 412441..414069 1 NC_008527.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 414069 groEL 4433104 groEL Lactococcus lactis subsp. cremoris SK11 chaperonin GroEL YP_808466.1 412441 D 272622 CDS YP_808467.1 116511251 4433105 complement(414121..414933) 1 NC_008527.1 beta-lactamase superfamily hydrolase 414933 4433105 LACR_0441 Lactococcus lactis subsp. cremoris SK11 beta-lactamase superfamily hydrolase YP_808467.1 414121 R 272622 CDS YP_808468.1 116511252 4433036 414935..415111 1 NC_008527.1 hypothetical protein 415111 4433036 LACR_0442 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808468.1 414935 D 272622 CDS YP_808469.1 116511253 4433037 complement(415123..416550) 1 NC_008527.1 Signal transduction histidine kinase 416550 4433037 LACR_0443 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_808469.1 415123 R 272622 CDS YP_808470.1 116511254 4433038 complement(416543..417244) 1 NC_008527.1 DNA-binding response regulator 417244 4433038 LACR_0444 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_808470.1 416543 R 272622 CDS YP_808471.1 116511255 4433039 417422..418057 1 NC_008527.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 418057 tmk 4433039 tmk Lactococcus lactis subsp. cremoris SK11 thymidylate kinase YP_808471.1 417422 D 272622 CDS YP_808472.1 116511256 4433040 418190..419050 1 NC_008527.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 419050 4433040 LACR_0446 Lactococcus lactis subsp. cremoris SK11 DNA polymerase III subunit delta' YP_808472.1 418190 D 272622 CDS YP_808473.1 116511257 4433041 419100..419882 1 NC_008527.1 signaling phosphorelay regulator protein 419882 4433041 LACR_0447 Lactococcus lactis subsp. cremoris SK11 signaling phosphorelay regulator protein YP_808473.1 419100 D 272622 CDS YP_808474.1 116511258 4433042 419875..420201 1 NC_008527.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 420201 4433042 LACR_0448 Lactococcus lactis subsp. cremoris SK11 DNA replication intiation control protein YabA YP_808474.1 419875 D 272622 CDS YP_808475.1 116511259 4433043 420201..421076 1 NC_008527.1 hypothetical protein 421076 4433043 LACR_0449 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808475.1 420201 D 272622 CDS YP_808476.1 116511260 4433044 complement(421154..421345) 1 NC_008527.1 hypothetical protein 421345 4433044 LACR_0450 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808476.1 421154 R 272622 CDS YP_808477.1 116511261 4433045 complement(421420..422229) 1 NC_008527.1 ABC-type multidrug transport system, permease component 422229 4433045 LACR_0451 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, permease component YP_808477.1 421420 R 272622 CDS YP_808478.1 116511262 4433046 complement(422242..423171) 1 NC_008527.1 ABC-type multidrug transport system, ATPase component 423171 4433046 LACR_0452 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase component YP_808478.1 422242 R 272622 CDS YP_808479.1 116511263 4433047 423303..423803 1 NC_008527.1 transcriptional regulator 423803 4433047 LACR_0453 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808479.1 423303 D 272622 CDS YP_808480.1 116511264 4433048 complement(423934..424866) 1 NC_008527.1 mevalonate kinase 424866 4433048 LACR_0454 Lactococcus lactis subsp. cremoris SK11 mevalonate kinase YP_808480.1 423934 R 272622 CDS YP_808481.1 116511265 4433049 425176..426132 1 NC_008527.1 diphosphomevalonate decarboxylase 426132 4433049 LACR_0455 Lactococcus lactis subsp. cremoris SK11 diphosphomevalonate decarboxylase YP_808481.1 425176 D 272622 CDS YP_808482.1 116511266 4433050 426119..427108 1 NC_008527.1 phosphomevalonate kinase 427108 4433050 LACR_0456 Lactococcus lactis subsp. cremoris SK11 phosphomevalonate kinase YP_808482.1 426119 D 272622 CDS YP_808483.1 116511267 4433051 427231..428280 1 NC_008527.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 428280 4433051 LACR_0457 Lactococcus lactis subsp. cremoris SK11 isopentenyl pyrophosphate isomerase YP_808483.1 427231 D 272622 CDS YP_808484.1 116511268 4433052 428434..429054 1 NC_008527.1 superoxide dismutase 429054 4433052 LACR_0458 Lactococcus lactis subsp. cremoris SK11 superoxide dismutase YP_808484.1 428434 D 272622 CDS YP_808485.1 116511269 4433053 429305..431659 1 NC_008527.1 carbon starvation protein, membrane protein 431659 4433053 LACR_0459 Lactococcus lactis subsp. cremoris SK11 carbon starvation protein, membrane protein YP_808485.1 429305 D 272622 CDS YP_808486.1 116511270 4433002 complement(431840..432541) 1 NC_008527.1 Acyl carrier protein phosphodiesterase 432541 4433002 LACR_0460 Lactococcus lactis subsp. cremoris SK11 Acyl carrier protein phosphodiesterase YP_808486.1 431840 R 272622 CDS YP_808487.1 116511271 4433004 433672..435012 1 NC_008527.1 superfamily II DNA/RNA helicase 435012 4433004 LACR_0462 Lactococcus lactis subsp. cremoris SK11 superfamily II DNA/RNA helicase YP_808487.1 433672 D 272622 CDS YP_808488.1 116511272 4433005 435063..435599 1 NC_008527.1 hypothetical protein 435599 4433005 LACR_0463 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808488.1 435063 D 272622 CDS YP_808489.1 116511273 4433006 435715..436461 1 NC_008527.1 transcriptional regulator 436461 4433006 LACR_0464 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808489.1 435715 D 272622 CDS YP_808490.1 116511274 4433007 436704..437030 1 NC_008527.1 cellobiose-specific PTS system IIB component 437030 4433007 LACR_0465 Lactococcus lactis subsp. cremoris SK11 cellobiose-specific PTS system IIB component YP_808490.1 436704 D 272622 CDS YP_808491.1 116511275 4433008 437113..437463 1 NC_008527.1 cellobiose-specific PTS system IIA component 437463 4433008 LACR_0466 Lactococcus lactis subsp. cremoris SK11 cellobiose-specific PTS system IIA component YP_808491.1 437113 D 272622 CDS YP_808492.1 116511276 4433009 437557..438285 1 NC_008527.1 transcriptional regulator 438285 4433009 LACR_0467 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808492.1 437557 D 272622 CDS YP_808493.1 116511277 4433010 438578..439915 1 NC_008527.1 cellobiose-specific PTS system IIC component 439915 4433010 LACR_0468 Lactococcus lactis subsp. cremoris SK11 cellobiose-specific PTS system IIC component YP_808493.1 438578 D 272622 CDS YP_808494.1 116511278 4433011 440005..441441 1 NC_008527.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 441441 celA 4433011 celA Lactococcus lactis subsp. cremoris SK11 6-phospho-beta-glucosidase YP_808494.1 440005 D 272622 CDS YP_808495.1 116511279 4433014 442374..444434 1 NC_008527.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 444434 ligA 4433014 ligA Lactococcus lactis subsp. cremoris SK11 NAD-dependent DNA ligase LigA YP_808495.1 442374 D 272622 CDS YP_808496.2 161777614 4433015 444575..445603 1 NC_008527.1 similar to YegS from E. coli; putative lipid kinase 445603 4433015 LACR_0473 Lactococcus lactis subsp. cremoris SK11 putative lipid kinase YP_808496.2 444575 D 272622 CDS YP_808497.1 116511281 4433016 445826..446962 1 NC_008527.1 ABC-type sugar transport system, ATPase component 446962 4433016 LACR_0474 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, ATPase component YP_808497.1 445826 D 272622 CDS YP_808498.1 116511282 4433017 447269..450940 1 NC_008527.1 pyruvate:ferredoxin oxidoreductase, fusion of alpha, beta and gamma subunit 450940 4433017 LACR_0475 Lactococcus lactis subsp. cremoris SK11 pyruvate:ferredoxin oxidoreductase, fusion of alpha, beta and gamma subunit YP_808498.1 447269 D 272622 CDS YP_808499.1 116511283 4432379 complement(451031..451921) 1 NC_008527.1 transposase 451921 4432379 LACR_0476 Lactococcus lactis subsp. cremoris SK11 transposase YP_808499.1 451031 R 272622 CDS YP_808500.1 116511284 4432380 452121..452999 1 NC_008527.1 hypothetical protein 452999 4432380 LACR_0477 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808500.1 452121 D 272622 CDS YP_808501.1 116511285 4432381 452989..453948 1 NC_008527.1 hypothetical protein 453948 4432381 LACR_0478 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808501.1 452989 D 272622 CDS YP_808502.1 116511286 4432382 453993..455351 1 NC_008527.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 455351 glmM 4432382 glmM Lactococcus lactis subsp. cremoris SK11 phosphoglucosamine mutase YP_808502.1 453993 D 272622 CDS YP_808503.1 116511287 4432383 complement(455425..456126) 1 NC_008527.1 GntR family transcriptional regulator 456126 4432383 LACR_0480 Lactococcus lactis subsp. cremoris SK11 GntR family transcriptional regulator YP_808503.1 455425 R 272622 CDS YP_808504.1 116511288 4432384 456252..456737 1 NC_008527.1 phosphotransferase system IIA component 456737 4432384 LACR_0481 Lactococcus lactis subsp. cremoris SK11 phosphotransferase system IIA component YP_808504.1 456252 D 272622 CDS YP_808505.1 116511289 4432385 456883..458448 1 NC_008527.1 beta-glucoside-specific PTS system IIABC component 458448 4432385 LACR_0482 Lactococcus lactis subsp. cremoris SK11 beta-glucoside-specific PTS system IIABC component YP_808505.1 456883 D 272622 CDS YP_808506.1 116511290 4432386 458515..460824 1 NC_008527.1 trehalose and maltose hydrolase ( phosphorylase) 460824 4432386 LACR_0483 Lactococcus lactis subsp. cremoris SK11 trehalose and maltose hydrolase ( phosphorylase) YP_808506.1 458515 D 272622 CDS YP_808507.1 116511291 4432387 460977..461642 1 NC_008527.1 HAD family sugar phosphatase 461642 4432387 LACR_0484 Lactococcus lactis subsp. cremoris SK11 HAD family sugar phosphatase YP_808507.1 460977 D 272622 CDS YP_808508.1 116511292 4432388 complement(461700..462467) 1 NC_008527.1 esterase/lipase 462467 4432388 LACR_0485 Lactococcus lactis subsp. cremoris SK11 esterase/lipase YP_808508.1 461700 R 272622 CDS YP_808509.1 116511293 4432389 462579..463277 1 NC_008527.1 hypothetical protein 463277 4432389 LACR_0486 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808509.1 462579 D 272622 CDS YP_808510.1 116511294 4432390 463436..463882 1 NC_008527.1 hypothetical protein 463882 4432390 LACR_0487 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808510.1 463436 D 272622 CDS YP_808511.1 116511295 4432391 463879..464397 1 NC_008527.1 acetyltransferase 464397 4432391 LACR_0488 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808511.1 463879 D 272622 CDS YP_808512.1 116511296 4432392 464529..465881 1 NC_008527.1 transcription regulator 465881 4432392 LACR_0489 Lactococcus lactis subsp. cremoris SK11 transcription regulator YP_808512.1 464529 D 272622 CDS YP_808513.1 116511297 4432394 466282..467043 1 NC_008527.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 467043 truA 4432394 truA Lactococcus lactis subsp. cremoris SK11 tRNA pseudouridine synthase A YP_808513.1 466282 D 272622 CDS YP_808514.1 116511298 4432395 467077..467865 1 NC_008527.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 467865 4432395 LACR_0492 Lactococcus lactis subsp. cremoris SK11 phosphomethylpyrimidine kinase YP_808514.1 467077 D 272622 CDS YP_808515.1 116511299 4434251 467914..468405 1 NC_008527.1 hypothetical protein 468405 4434251 LACR_0493 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808515.1 467914 D 272622 CDS YP_808516.1 116511300 4434252 468386..468928 1 NC_008527.1 hypothetical protein 468928 4434252 LACR_0494 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808516.1 468386 D 272622 CDS YP_808517.1 116511301 4434254 469651..470064 1 NC_008527.1 Serine-pyruvate aminotransferase 470064 4434254 LACR_0496 Lactococcus lactis subsp. cremoris SK11 Serine-pyruvate aminotransferase YP_808517.1 469651 D 272622 CDS YP_808518.1 116511302 4434255 470341..471948 1 NC_008527.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 471948 pyrG 4434255 pyrG Lactococcus lactis subsp. cremoris SK11 CTP synthetase YP_808518.1 470341 D 272622 CDS YP_808519.1 116511303 4434256 472160..473017 1 NC_008527.1 hypothetical protein 473017 4434256 LACR_0498 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808519.1 472160 D 272622 CDS YP_808520.1 116511304 4434257 472998..473396 1 NC_008527.1 hypothetical protein 473396 4434257 LACR_0499 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808520.1 472998 D 272622 CDS YP_808521.1 116511305 4434258 473399..473887 1 NC_008527.1 hypothetical protein 473887 4434258 LACR_0500 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808521.1 473399 D 272622 CDS YP_808522.1 116511306 4434259 473884..474441 1 NC_008527.1 hypothetical protein 474441 4434259 LACR_0501 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808522.1 473884 D 272622 CDS YP_808523.1 116511307 4434260 474672..475559 1 NC_008527.1 hypothetical protein 475559 4434260 LACR_0502 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808523.1 474672 D 272622 CDS YP_808524.1 116511308 4434261 475556..476086 1 NC_008527.1 hypothetical protein 476086 4434261 LACR_0503 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808524.1 475556 D 272622 CDS YP_808525.1 116511309 4434262 476093..476665 1 NC_008527.1 hypothetical protein 476665 4434262 LACR_0504 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808525.1 476093 D 272622 CDS YP_808526.1 116511310 4434263 476676..477236 1 NC_008527.1 hypothetical protein 477236 4434263 LACR_0505 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808526.1 476676 D 272622 CDS YP_808527.1 116511311 4434264 477208..477699 1 NC_008527.1 hypothetical protein 477699 4434264 LACR_0506 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808527.1 477208 D 272622 CDS YP_808528.1 116511312 4434265 477755..477913 1 NC_008527.1 hypothetical protein 477913 4434265 LACR_0507 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808528.1 477755 D 272622 CDS YP_808529.1 116511313 4434266 477932..478189 1 NC_008527.1 hypothetical protein 478189 4434266 LACR_0508 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808529.1 477932 D 272622 CDS YP_808530.1 116511314 4434267 478193..478651 1 NC_008527.1 hypothetical protein 478651 4434267 LACR_0509 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808530.1 478193 D 272622 CDS YP_808531.1 116511315 4433697 478669..479583 1 NC_008527.1 malate dehydrogenase (NAD) 479583 4433697 LACR_0510 Lactococcus lactis subsp. cremoris SK11 malate dehydrogenase (NAD) YP_808531.1 478669 D 272622 CDS YP_808532.1 116511316 4433698 complement(479618..480499) 1 NC_008527.1 hypothetical protein 480499 4433698 LACR_0511 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808532.1 479618 R 272622 CDS YP_808533.1 116511317 4433699 complement(480856..481056) 1 NC_008527.1 hypothetical protein 481056 4433699 LACR_0512 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808533.1 480856 R 272622 CDS YP_808534.1 116511318 4433701 complement(481608..482162) 1 NC_008527.1 hypothetical protein 482162 4433701 LACR_0514 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808534.1 481608 R 272622 CDS YP_808535.1 116511319 4433702 complement(482162..482815) 1 NC_008527.1 deoxynucleoside kinase 482815 4433702 LACR_0515 Lactococcus lactis subsp. cremoris SK11 deoxynucleoside kinase YP_808535.1 482162 R 272622 CDS YP_808536.1 116511320 4433703 complement(483341..484516) 1 NC_008527.1 transposase 484516 4433703 LACR_0516 Lactococcus lactis subsp. cremoris SK11 transposase YP_808536.1 483341 R 272622 CDS YP_808537.1 116511321 4433705 485751..486884 1 NC_008527.1 hypothetical protein 486884 4433705 LACR_0518 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808537.1 485751 D 272622 CDS YP_808538.1 116511322 4433706 487112..490324 1 NC_008527.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 490324 dnaE 4433706 dnaE Lactococcus lactis subsp. cremoris SK11 DNA polymerase III DnaE YP_808538.1 487112 D 272622 CDS YP_808539.1 116511323 4433707 complement(490356..491009) 1 NC_008527.1 hemolysin like protein 491009 4433707 LACR_0520 Lactococcus lactis subsp. cremoris SK11 hemolysin like protein YP_808539.1 490356 R 272622 CDS YP_808540.1 116511324 4433708 491211..492047 1 NC_008527.1 hypothetical protein 492047 4433708 LACR_0521 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808540.1 491211 D 272622 CDS YP_808541.1 116511325 4433709 492102..492941 1 NC_008527.1 lysophospholipase L1 related esterase 492941 4433709 LACR_0522 Lactococcus lactis subsp. cremoris SK11 lysophospholipase L1 related esterase YP_808541.1 492102 D 272622 CDS YP_808542.1 116511326 4433710 492938..494149 1 NC_008527.1 Beta-glucosidase-related glycosidase 494149 4433710 LACR_0523 Lactococcus lactis subsp. cremoris SK11 Beta-glucosidase-related glycosidase YP_808542.1 492938 D 272622 CDS YP_808543.1 116511327 4433711 494158..494814 1 NC_008527.1 hypothetical protein 494814 4433711 LACR_0524 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808543.1 494158 D 272622 CDS YP_808544.1 116511328 4433712 494919..495194 1 NC_008527.1 nucleoid protein Hbs 495194 4433712 LACR_0525 Lactococcus lactis subsp. cremoris SK11 nucleoid protein Hbs YP_808544.1 494919 D 272622 CDS YP_808545.1 116511329 4433713 complement(495305..495802) 1 NC_008527.1 acetyltransferase 495802 4433713 LACR_0526 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808545.1 495305 R 272622 CDS YP_808546.1 116511330 4433648 498015..498824 1 NC_008527.1 ABC transporter ATP-binding protein 498824 4433648 LACR_0530 Lactococcus lactis subsp. cremoris SK11 ABC transporter ATP-binding protein YP_808546.1 498015 D 272622 CDS YP_808547.1 116511331 4433649 498821..499546 1 NC_008527.1 ABC transporter permease 499546 4433649 LACR_0531 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease YP_808547.1 498821 D 272622 CDS YP_808548.1 116511332 4433650 499656..500066 1 NC_008527.1 response regulator 500066 4433650 LACR_0532 Lactococcus lactis subsp. cremoris SK11 response regulator YP_808548.1 499656 D 272622 CDS YP_808549.1 116511333 4433651 500063..500440 1 NC_008527.1 hypothetical protein 500440 4433651 LACR_0533 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808549.1 500063 D 272622 CDS YP_808550.1 116511334 4433652 500549..501694 1 NC_008527.1 pyridoxal-phosphate dependent aminotransferase 501694 4433652 LACR_0534 Lactococcus lactis subsp. cremoris SK11 pyridoxal-phosphate dependent aminotransferase YP_808550.1 500549 D 272622 CDS YP_808551.1 116511335 4433653 501844..502722 1 NC_008527.1 YG repeat-containing cell wall-associated hydrolase 502722 4433653 LACR_0535 Lactococcus lactis subsp. cremoris SK11 YG repeat-containing cell wall-associated hydrolase YP_808551.1 501844 D 272622 CDS YP_808552.1 116511336 4433654 complement(502779..504428) 1 NC_008527.1 ABC-type oligopeptide transport system, periplasmic component 504428 4433654 LACR_0536 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, periplasmic component YP_808552.1 502779 R 272622 CDS YP_808553.1 116511337 4433655 complement(504620..505585) 1 NC_008527.1 cysteine synthase 505585 4433655 LACR_0537 Lactococcus lactis subsp. cremoris SK11 cysteine synthase YP_808553.1 504620 R 272622 CDS YP_808554.1 116511338 4433656 505771..506856 1 NC_008527.1 muramidase (flagellum-specific) 506856 4433656 LACR_0538 Lactococcus lactis subsp. cremoris SK11 muramidase (flagellum-specific) YP_808554.1 505771 D 272622 CDS YP_808555.1 116511339 4433657 complement(506891..507523) 1 NC_008527.1 Zn-dependent hydrolase, including glyoxylase 507523 4433657 LACR_0539 Lactococcus lactis subsp. cremoris SK11 Zn-dependent hydrolase, including glyoxylase YP_808555.1 506891 R 272622 CDS YP_808556.1 116511340 4433659 507837..508517 1 NC_008527.1 transposase 508517 4433659 LACR_0541 Lactococcus lactis subsp. cremoris SK11 transposase YP_808556.1 507837 D 272622 CDS YP_808557.1 116511341 4433660 complement(508551..510422) 1 NC_008527.1 membrane carboxypeptidase (penicillin-binding protein) 510422 4433660 LACR_0542 Lactococcus lactis subsp. cremoris SK11 membrane carboxypeptidase (penicillin-binding protein) YP_808557.1 508551 R 272622 CDS YP_808558.1 116511342 4433661 complement(510409..511050) 1 NC_008527.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 511050 recU 4433661 recU Lactococcus lactis subsp. cremoris SK11 Holliday junction-specific endonuclease YP_808558.1 510409 R 272622 CDS YP_808559.1 116511343 4433662 511131..511655 1 NC_008527.1 hypothetical protein 511655 4433662 LACR_0544 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808559.1 511131 D 272622 CDS YP_808560.1 116511344 4433546 511815..512201 1 NC_008527.1 arsenate reductase 512201 4433546 LACR_0545 Lactococcus lactis subsp. cremoris SK11 arsenate reductase YP_808560.1 511815 D 272622 CDS YP_808561.1 116511345 4433547 512422..512703 1 NC_008527.1 hypothetical protein 512703 4433547 LACR_0546 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808561.1 512422 D 272622 CDS YP_808562.1 116511346 4433548 512669..513448 1 NC_008527.1 fructose-1 6-bisphosphatase 513448 4433548 LACR_0547 Lactococcus lactis subsp. cremoris SK11 fructose-1 6-bisphosphatase YP_808562.1 512669 D 272622 CDS YP_808563.1 116511347 4433549 513543..514823 1 NC_008527.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 514823 4433549 LACR_0548 Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_808563.1 513543 D 272622 CDS YP_808564.1 116511348 4433550 514823..515014 1 NC_008527.1 hypothetical protein 515014 4433550 LACR_0549 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808564.1 514823 D 272622 CDS YP_808565.1 116511349 4433551 515190..516473 1 NC_008527.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 516473 tig 4433551 tig Lactococcus lactis subsp. cremoris SK11 trigger factor YP_808565.1 515190 D 272622 CDS YP_808566.1 116511350 4433552 516647..517822 1 NC_008527.1 transposase 517822 4433552 LACR_0551 Lactococcus lactis subsp. cremoris SK11 transposase YP_808566.1 516647 D 272622 CDS YP_808567.1 116511351 4433260 524653..526566 1 NC_008527.1 synthesizes RNA primers at the replication forks; DNA primase 526566 dnaG 4433260 dnaG Lactococcus lactis subsp. cremoris SK11 DNA primase YP_808567.1 524653 D 272622 CDS YP_808568.1 116511352 4433261 526643..527986 1 NC_008527.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 527986 4433261 LACR_0571 Lactococcus lactis subsp. cremoris SK11 RNA polymerase sigma factor RpoD YP_808568.1 526643 D 272622 CDS YP_808569.1 116511353 4433263 528994..530373 1 NC_008527.1 glycerol-3-phosphatase transporter 530373 4433263 LACR_0573 Lactococcus lactis subsp. cremoris SK11 glycerol-3-phosphatase transporter YP_808569.1 528994 D 272622 CDS YP_808570.1 116511354 4433264 530529..531398 1 NC_008527.1 hypothetical protein 531398 4433264 LACR_0574 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808570.1 530529 D 272622 CDS YP_808571.1 116511355 4433267 532901..533245 1 NC_008527.1 hypothetical protein 533245 4433267 LACR_0577 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808571.1 532901 D 272622 CDS YP_808572.1 116511356 4433268 533291..535537 1 NC_008527.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones 535537 4433268 LACR_0578 Lactococcus lactis subsp. cremoris SK11 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones YP_808572.1 533291 D 272622 CDS YP_808573.1 116511357 4433945 complement(535663..536133) 1 NC_008527.1 BadM/Rrf2 family transcriptional regulator 536133 4433945 LACR_0579 Lactococcus lactis subsp. cremoris SK11 BadM/Rrf2 family transcriptional regulator YP_808573.1 535663 R 272622 CDS YP_808574.1 116511358 4433946 536359..537372 1 NC_008527.1 glyceraldehyde 3-phosphate dehydrogenase 537372 4433946 LACR_0580 Lactococcus lactis subsp. cremoris SK11 glyceraldehyde 3-phosphate dehydrogenase YP_808574.1 536359 D 272622 CDS YP_808575.1 116511359 4433947 complement(537596..538231) 1 NC_008527.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 538231 def 4433947 def Lactococcus lactis subsp. cremoris SK11 peptide deformylase YP_808575.1 537596 R 272622 CDS YP_808576.1 116511360 4433948 538386..538790 1 NC_008527.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 538790 4433948 LACR_0582 Lactococcus lactis subsp. cremoris SK11 dinucleoside polyphosphate hydrolase YP_808576.1 538386 D 272622 CDS YP_808577.1 116511361 4433949 538852..540930 1 NC_008527.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 540930 4433949 LACR_0583 Lactococcus lactis subsp. cremoris SK11 excinuclease ABC subunit B YP_808577.1 538852 D 272622 CDS YP_808578.1 116511362 4433950 541112..541933 1 NC_008527.1 amino acid ABC transporter periplasmic protein 541933 4433950 LACR_0584 Lactococcus lactis subsp. cremoris SK11 amino acid ABC transporter periplasmic protein YP_808578.1 541112 D 272622 CDS YP_808579.1 116511363 4433952 complement(543118..543573) 1 NC_008527.1 (3R)-hydroxymyristoyl-ACP dehydratase 543573 4433952 LACR_0586 Lactococcus lactis subsp. cremoris SK11 (3R)-hydroxymyristoyl-ACP dehydratase YP_808579.1 543118 R 272622 CDS YP_808580.1 116511364 4433953 543849..544601 1 NC_008527.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 544601 4433953 LACR_0587 Lactococcus lactis subsp. cremoris SK11 enoyl-(acyl carrier protein) reductase YP_808580.1 543849 D 272622 CDS YP_808581.1 116511365 4433954 complement(544787..545749) 1 NC_008527.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 545749 4433954 LACR_0588 Lactococcus lactis subsp. cremoris SK11 OxaA-like protein precursor YP_808581.1 544787 R 272622 CDS YP_808582.1 116511366 4433955 complement(545924..546682) 1 NC_008527.1 HAD superfamily hydrolase 546682 4433955 LACR_0589 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_808582.1 545924 R 272622 CDS YP_808583.1 116511367 4433956 complement(546777..547367) 1 NC_008527.1 hypothetical protein 547367 4433956 LACR_0590 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808583.1 546777 R 272622 CDS YP_808584.1 116511368 4433958 complement(547913..548608) 1 NC_008527.1 phosphopantothenate--cysteine ligase 548608 4433958 LACR_0592 Lactococcus lactis subsp. cremoris SK11 phosphopantothenate--cysteine ligase YP_808584.1 547913 R 272622 CDS YP_808585.1 116511369 4433959 complement(548754..548939) 1 NC_008527.1 4-oxalocrotonate tautomerase 548939 4433959 LACR_0593 Lactococcus lactis subsp. cremoris SK11 4-oxalocrotonate tautomerase YP_808585.1 548754 R 272622 CDS YP_808586.1 116511370 4433960 549125..551452 1 NC_008527.1 cation transport ATPase 551452 4433960 LACR_0594 Lactococcus lactis subsp. cremoris SK11 cation transport ATPase YP_808586.1 549125 D 272622 CDS YP_808587.1 116511371 4433961 551485..551928 1 NC_008527.1 acetyltransferase 551928 4433961 LACR_0595 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808587.1 551485 D 272622 CDS YP_808588.1 116511372 4433716 complement(552375..553229) 1 NC_008527.1 transposase 553229 4433716 LACR_0597 Lactococcus lactis subsp. cremoris SK11 transposase YP_808588.1 552375 R 272622 CDS YP_808589.1 116511373 4433717 complement(553226..553486) 1 NC_008527.1 transposase 553486 4433717 LACR_0598 Lactococcus lactis subsp. cremoris SK11 transposase YP_808589.1 553226 R 272622 CDS YP_808590.1 116511374 4433718 553558..553674 1 NC_008527.1 hypothetical protein 553674 4433718 LACR_0599 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808590.1 553558 D 272622 CDS YP_808591.1 116511375 4433719 553704..554534 1 NC_008527.1 hypothetical protein 554534 4433719 LACR_0600 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808591.1 553704 D 272622 CDS YP_808592.1 116511376 4433720 554461..554586 1 NC_008527.1 hypothetical protein 554586 4433720 LACR_0601 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808592.1 554461 D 272622 CDS YP_808593.1 116511377 4433721 554741..555058 1 NC_008527.1 hypothetical protein 555058 4433721 LACR_0602 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808593.1 554741 D 272622 CDS YP_808594.1 116511378 4433723 556131..556745 1 NC_008527.1 hypothetical protein 556745 4433723 LACR_0604 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808594.1 556131 D 272622 CDS YP_808595.1 116511379 4433724 556763..557806 1 NC_008527.1 hypothetical protein 557806 4433724 LACR_0605 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808595.1 556763 D 272622 CDS YP_808596.1 116511380 4433725 557806..558021 1 NC_008527.1 hypothetical protein 558021 4433725 LACR_0606 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808596.1 557806 D 272622 CDS YP_808597.1 116511381 4433726 558081..559205 1 NC_008527.1 integrase 559205 4433726 LACR_0607 Lactococcus lactis subsp. cremoris SK11 integrase YP_808597.1 558081 D 272622 CDS YP_808598.1 116511382 4433727 559375..559944 1 NC_008527.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 559944 4433727 LACR_0608 Lactococcus lactis subsp. cremoris SK11 thymidine kinase YP_808598.1 559375 D 272622 CDS YP_808599.1 116511383 4433728 559955..560398 1 NC_008527.1 hypothetical protein 560398 4433728 LACR_0609 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808599.1 559955 D 272622 CDS YP_808600.1 116511384 4433729 560416..561489 1 NC_008527.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 561489 prfA 4433729 prfA Lactococcus lactis subsp. cremoris SK11 peptide chain release factor 1 YP_808600.1 560416 D 272622 CDS YP_808601.1 116511385 4433730 561489..562016 1 NC_008527.1 hypothetical protein 562016 4433730 LACR_0611 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808601.1 561489 D 272622 CDS YP_808602.1 116511386 4433731 561977..562093 1 NC_008527.1 hypothetical protein 562093 4433731 LACR_0612 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808602.1 561977 D 272622 CDS YP_808603.1 116511387 4433732 562086..562841 1 NC_008527.1 NADPH-flavin oxidoreductase 562841 4433732 LACR_0613 Lactococcus lactis subsp. cremoris SK11 NADPH-flavin oxidoreductase YP_808603.1 562086 D 272622 CDS YP_808604.1 116511388 4434086 562946..563761 1 NC_008527.1 methylase of polypeptide chain release factor 563761 4434086 LACR_0614 Lactococcus lactis subsp. cremoris SK11 methylase of polypeptide chain release factor YP_808604.1 562946 D 272622 CDS YP_808605.1 116511389 4434087 563792..564256 1 NC_008527.1 acetyltransferase 564256 4434087 LACR_0615 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808605.1 563792 D 272622 CDS YP_808606.1 116511390 4434088 564253..565173 1 NC_008527.1 translation factor SUA5 565173 4434088 LACR_0616 Lactococcus lactis subsp. cremoris SK11 translation factor SUA5 YP_808606.1 564253 D 272622 CDS YP_808607.1 116511391 4434089 565406..566653 1 NC_008527.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 566653 glyA 4434089 glyA Lactococcus lactis subsp. cremoris SK11 serine hydroxymethyltransferase YP_808607.1 565406 D 272622 CDS YP_808608.1 116511392 4434090 566834..567436 1 NC_008527.1 soluble lytic murein transglycosylase related regulatory protein 567436 4434090 LACR_0618 Lactococcus lactis subsp. cremoris SK11 soluble lytic murein transglycosylase related regulatory protein YP_808608.1 566834 D 272622 CDS YP_808609.1 116511393 4434091 567563..568660 1 NC_008527.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 568660 4434091 LACR_0619 Lactococcus lactis subsp. cremoris SK11 phosphoserine aminotransferase YP_808609.1 567563 D 272622 CDS YP_808610.1 116511394 4434092 568657..569853 1 NC_008527.1 D-3-phosphoglycerate dehydrogenase 569853 4434092 LACR_0620 Lactococcus lactis subsp. cremoris SK11 D-3-phosphoglycerate dehydrogenase YP_808610.1 568657 D 272622 CDS YP_808611.1 116511395 4434093 569899..570561 1 NC_008527.1 phosphoserine phosphatase 570561 4434093 LACR_0621 Lactococcus lactis subsp. cremoris SK11 phosphoserine phosphatase YP_808611.1 569899 D 272622 CDS YP_808612.1 116511396 4434094 complement(570598..570891) 1 NC_008527.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 570891 4434094 LACR_0622 Lactococcus lactis subsp. cremoris SK11 acylphosphatase YP_808612.1 570598 R 272622 CDS YP_808613.1 116511397 4434095 571003..571761 1 NC_008527.1 rRNA methylase 571761 4434095 LACR_0623 Lactococcus lactis subsp. cremoris SK11 rRNA methylase YP_808613.1 571003 D 272622 CDS YP_808614.1 116511398 4434096 complement(571973..572362) 1 NC_008527.1 hypothetical protein 572362 4434096 LACR_0624 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808614.1 571973 R 272622 CDS YP_808615.1 116511399 4434097 complement(572362..572589) 1 NC_008527.1 hypothetical protein 572589 4434097 LACR_0625 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808615.1 572362 R 272622 CDS YP_808616.1 116511400 4434098 572668..573015 1 NC_008527.1 transcriptional regulator 573015 4434098 LACR_0626 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808616.1 572668 D 272622 CDS YP_808617.1 116511401 4434099 573029..573355 1 NC_008527.1 inorganic pyrophosphatase 573355 4434099 LACR_0627 Lactococcus lactis subsp. cremoris SK11 inorganic pyrophosphatase YP_808617.1 573029 D 272622 CDS YP_808618.1 116511402 4434100 complement(573531..573974) 1 NC_008527.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 573974 4434100 LACR_0628 Lactococcus lactis subsp. cremoris SK11 flavodoxin YP_808618.1 573531 R 272622 CDS YP_808619.1 116511403 4434101 complement(574234..575544) 1 NC_008527.1 major facilitator superfamily permease 575544 4434101 LACR_0629 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808619.1 574234 R 272622 CDS YP_808620.1 116511404 4434102 575799..576428 1 NC_008527.1 transcriptional regulator 576428 4434102 LACR_0630 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808620.1 575799 D 272622 CDS YP_808621.1 116511405 4433324 576708..577562 1 NC_008527.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 577562 4433324 LACR_0631 Lactococcus lactis subsp. cremoris SK11 methionine aminopeptidase YP_808621.1 576708 D 272622 CDS YP_808622.1 116511406 4433325 577585..578490 1 NC_008527.1 ribonuclease BN-like family protein 578490 4433325 LACR_0632 Lactococcus lactis subsp. cremoris SK11 ribonuclease BN-like family protein YP_808622.1 577585 D 272622 CDS YP_808623.1 116511407 4433326 complement(578593..579039) 1 NC_008527.1 GtcA family membrane protein 579039 4433326 LACR_0633 Lactococcus lactis subsp. cremoris SK11 GtcA family membrane protein YP_808623.1 578593 R 272622 CDS YP_808624.1 116511408 4433328 579440..579916 1 NC_008527.1 hypothetical protein 579916 4433328 LACR_0635 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808624.1 579440 D 272622 CDS YP_808625.1 116511409 4433329 579948..580223 1 NC_008527.1 hypothetical protein 580223 4433329 LACR_0636 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808625.1 579948 D 272622 CDS YP_808626.1 116511410 4433330 580326..580502 1 NC_008527.1 hypothetical protein 580502 4433330 LACR_0637 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808626.1 580326 D 272622 CDS YP_808627.1 116511411 4433331 580635..581567 1 NC_008527.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 581567 4433331 LACR_0638 Lactococcus lactis subsp. cremoris SK11 HPr kinase/phosphorylase YP_808627.1 580635 D 272622 CDS YP_808628.1 116511412 4433332 581629..582414 1 NC_008527.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 582414 4433332 LACR_0639 Lactococcus lactis subsp. cremoris SK11 prolipoprotein diacylglyceryl transferase YP_808628.1 581629 D 272622 CDS YP_808629.1 116511413 4433333 582581..583000 1 NC_008527.1 methyl-accepting chemotaxis-like protein 583000 4433333 LACR_0640 Lactococcus lactis subsp. cremoris SK11 methyl-accepting chemotaxis-like protein YP_808629.1 582581 D 272622 CDS YP_808630.1 116511414 4433334 583030..583590 1 NC_008527.1 hypothetical protein 583590 4433334 LACR_0641 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808630.1 583030 D 272622 CDS YP_808631.1 116511415 4433335 583724..585142 1 NC_008527.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 585142 4433335 LACR_0642 Lactococcus lactis subsp. cremoris SK11 6-phosphogluconate dehydrogenase YP_808631.1 583724 D 272622 CDS YP_808632.1 116511416 4433336 585324..587345 1 NC_008527.1 K+ transporter 587345 4433336 LACR_0643 Lactococcus lactis subsp. cremoris SK11 K+ transporter YP_808632.1 585324 D 272622 CDS YP_808633.1 116511417 4433337 587560..589575 1 NC_008527.1 K+ transporter 589575 4433337 LACR_0644 Lactococcus lactis subsp. cremoris SK11 K+ transporter YP_808633.1 587560 D 272622 CDS YP_808634.1 116511418 4433338 complement(589628..589798) 1 NC_008527.1 hypothetical protein 589798 4433338 LACR_0645 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808634.1 589628 R 272622 CDS YP_808635.1 116511419 4433339 589993..590658 1 NC_008527.1 hypothetical protein 590658 4433339 LACR_0646 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808635.1 589993 D 272622 CDS YP_808636.1 116511420 4433340 590790..591674 1 NC_008527.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 591674 miaA 4433340 miaA Lactococcus lactis subsp. cremoris SK11 tRNA delta(2)-isopentenylpyrophosphate transferase YP_808636.1 590790 D 272622 CDS YP_808637.1 116511421 4433341 591820..592488 1 NC_008527.1 hypothetical protein 592488 4433341 LACR_0648 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808637.1 591820 D 272622 CDS YP_808638.1 116511422 4433193 592653..593555 1 NC_008527.1 membrane protease family stomatin/prohibitin-like protein 593555 4433193 LACR_0649 Lactococcus lactis subsp. cremoris SK11 membrane protease family stomatin/prohibitin-like protein YP_808638.1 592653 D 272622 CDS YP_808639.1 116511423 4433195 complement(593804..594502) 1 NC_008527.1 surface antigen 594502 4433195 LACR_0651 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_808639.1 593804 R 272622 CDS YP_808640.1 116511424 4433196 complement(594929..595276) 1 NC_008527.1 XRE family transcriptional regulator 595276 4433196 LACR_0652 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_808640.1 594929 R 272622 CDS YP_808641.1 116511425 4433198 596041..596964 1 NC_008527.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 596964 4433198 LACR_0654 Lactococcus lactis subsp. cremoris SK11 ribonuclease Z YP_808641.1 596041 D 272622 CDS YP_808642.1 116511426 4433199 596957..597658 1 NC_008527.1 Short-chain dehydrogenase of various substrate specificities 597658 4433199 LACR_0655 Lactococcus lactis subsp. cremoris SK11 Short-chain dehydrogenase of various substrate specificities YP_808642.1 596957 D 272622 CDS YP_808643.1 116511427 4433200 597831..600059 1 NC_008527.1 exonuclease RecJ 600059 4433200 LACR_0656 Lactococcus lactis subsp. cremoris SK11 exonuclease RecJ YP_808643.1 597831 D 272622 CDS YP_808644.1 116511428 4433201 600183..600695 1 NC_008527.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 600695 4433201 LACR_0657 Lactococcus lactis subsp. cremoris SK11 adenine phosphoribosyltransferase YP_808644.1 600183 D 272622 CDS YP_808645.1 116511429 4433202 600886..601449 1 NC_008527.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 601449 4433202 LACR_0658 Lactococcus lactis subsp. cremoris SK11 DNA-directed RNA polymerase subunit delta YP_808645.1 600886 D 272622 CDS YP_808646.1 116511430 4433203 601585..603225 1 NC_008527.1 aminodeoxychorismate lyase 603225 4433203 LACR_0659 Lactococcus lactis subsp. cremoris SK11 aminodeoxychorismate lyase YP_808646.1 601585 D 272622 CDS YP_808647.1 116511431 4433204 603286..603756 1 NC_008527.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 603756 greA 4433204 greA Lactococcus lactis subsp. cremoris SK11 transcription elongation factor GreA YP_808647.1 603286 D 272622 CDS YP_808648.1 116511432 4433205 603848..604405 1 NC_008527.1 transposase 604405 4433205 LACR_0661 Lactococcus lactis subsp. cremoris SK11 transposase YP_808648.1 603848 D 272622 CDS YP_808649.1 116511433 4433206 604402..605223 1 NC_008527.1 transposase 605223 4433206 LACR_0662 Lactococcus lactis subsp. cremoris SK11 transposase YP_808649.1 604402 D 272622 CDS YP_808650.1 116511434 4433207 complement(605278..606117) 1 NC_008527.1 transposase 606117 4433207 LACR_0663 Lactococcus lactis subsp. cremoris SK11 transposase YP_808650.1 605278 R 272622 CDS YP_808651.1 116511435 4433054 complement(606135..606425) 1 NC_008527.1 transposase 606425 4433054 LACR_0664 Lactococcus lactis subsp. cremoris SK11 transposase YP_808651.1 606135 R 272622 CDS YP_808652.1 116511436 4433055 606672..607127 1 NC_008527.1 transcriptional repressor of class III stress genes 607127 4433055 LACR_0665 Lactococcus lactis subsp. cremoris SK11 transcriptional repressor of class III stress genes YP_808652.1 606672 D 272622 CDS YP_808653.1 116511437 4433056 607117..609567 1 NC_008527.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones 609567 4433056 LACR_0666 Lactococcus lactis subsp. cremoris SK11 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones YP_808653.1 607117 D 272622 CDS YP_808654.1 116511438 4433057 609702..610259 1 NC_008527.1 sigma 54 modulation protein / SSU ribosomal protein S30P 610259 4433057 LACR_0667 Lactococcus lactis subsp. cremoris SK11 sigma 54 modulation protein / SSU ribosomal protein S30P YP_808654.1 609702 D 272622 CDS YP_808655.1 116511439 4433058 610447..611748 1 NC_008527.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 611748 eno 4433058 eno Lactococcus lactis subsp. cremoris SK11 phosphopyruvate hydratase YP_808655.1 610447 D 272622 CDS YP_808656.1 116511440 4433059 611836..612771 1 NC_008527.1 integrase-recombinase 612771 4433059 LACR_0669 Lactococcus lactis subsp. cremoris SK11 integrase-recombinase YP_808656.1 611836 D 272622 CDS YP_808657.1 116511441 4433060 612898..613023 1 NC_008527.1 hypothetical protein 613023 4433060 LACR_0670 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808657.1 612898 D 272622 CDS YP_808658.1 116511442 4433061 613044..613811 1 NC_008527.1 hypothetical protein 613811 4433061 LACR_0671 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808658.1 613044 D 272622 CDS YP_808659.1 116511443 4433062 613924..614121 1 NC_008527.1 hypothetical protein 614121 4433062 LACR_0672 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808659.1 613924 D 272622 CDS YP_808660.1 116511444 4433063 complement(614118..615293) 1 NC_008527.1 transposase 615293 4433063 LACR_0673 Lactococcus lactis subsp. cremoris SK11 transposase YP_808660.1 614118 R 272622 CDS YP_808661.1 116511445 4433064 615915..616064 1 NC_008527.1 hypothetical protein 616064 4433064 LACR_0674 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808661.1 615915 D 272622 CDS YP_808662.1 116511446 4433065 complement(616065..616955) 1 NC_008527.1 transposase 616955 4433065 LACR_0675 Lactococcus lactis subsp. cremoris SK11 transposase YP_808662.1 616065 R 272622 CDS YP_808663.1 116511447 4433066 617497..617673 1 NC_008527.1 hypothetical protein 617673 4433066 LACR_0676 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808663.1 617497 D 272622 CDS YP_808664.1 116511448 4433067 617711..618979 1 NC_008527.1 hypothetical protein 618979 4433067 LACR_0677 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808664.1 617711 D 272622 CDS YP_808665.1 116511449 4433068 619016..619141 1 NC_008527.1 hypothetical protein 619141 4433068 LACR_0678 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808665.1 619016 D 272622 CDS YP_808666.1 116511450 4433069 619712..620602 1 NC_008527.1 transposase 620602 4433069 LACR_0679 Lactococcus lactis subsp. cremoris SK11 transposase YP_808666.1 619712 D 272622 CDS YP_808667.1 116511451 4433070 621066..621326 1 NC_008527.1 transposase 621326 4433070 LACR_0680 Lactococcus lactis subsp. cremoris SK11 transposase YP_808667.1 621066 D 272622 CDS YP_808668.1 116511452 4433071 621323..622177 1 NC_008527.1 transposase 622177 4433071 LACR_0681 Lactococcus lactis subsp. cremoris SK11 transposase YP_808668.1 621323 D 272622 CDS YP_808669.1 116511453 4433594 622234..622959 1 NC_008527.1 hypothetical protein 622959 4433594 LACR_0682 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808669.1 622234 D 272622 CDS YP_808670.1 116511454 4433595 623588..624586 1 NC_008527.1 hypothetical protein 624586 4433595 LACR_0683 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808670.1 623588 D 272622 CDS YP_808671.1 116511455 4433596 complement(624829..625683) 1 NC_008527.1 transposase 625683 4433596 LACR_0684 Lactococcus lactis subsp. cremoris SK11 transposase YP_808671.1 624829 R 272622 CDS YP_808672.1 116511456 4433597 complement(625680..625940) 1 NC_008527.1 transposase 625940 4433597 LACR_0685 Lactococcus lactis subsp. cremoris SK11 transposase YP_808672.1 625680 R 272622 CDS YP_808673.1 116511457 4433598 complement(626273..626944) 1 NC_008527.1 peptide ABC transporter ATPase 626944 4433598 LACR_0686 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter ATPase YP_808673.1 626273 R 272622 CDS YP_808674.1 116511458 4433599 complement(626946..628019) 1 NC_008527.1 peptide ABC transporter permease 628019 4433599 LACR_0687 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter permease YP_808674.1 626946 R 272622 CDS YP_808675.1 116511459 4433600 complement(628031..628600) 1 NC_008527.1 transcriptional regulator 628600 4433600 LACR_0688 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808675.1 628031 R 272622 CDS YP_808676.1 116511460 4433601 complement(628787..630310) 1 NC_008527.1 long-chain acyl-CoA synthetase 630310 4433601 LACR_0689 Lactococcus lactis subsp. cremoris SK11 long-chain acyl-CoA synthetase YP_808676.1 628787 R 272622 CDS YP_808677.1 116511461 4433602 630539..631420 1 NC_008527.1 divalent cation transport-related protein 631420 4433602 LACR_0690 Lactococcus lactis subsp. cremoris SK11 divalent cation transport-related protein YP_808677.1 630539 D 272622 CDS YP_808678.1 116511462 4433603 631681..634044 1 NC_008527.1 pyruvate-formate lyase 634044 4433603 LACR_0691 Lactococcus lactis subsp. cremoris SK11 pyruvate-formate lyase YP_808678.1 631681 D 272622 CDS YP_808679.1 116511463 4433604 634275..634934 1 NC_008527.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 634934 coaE 4433604 coaE Lactococcus lactis subsp. cremoris SK11 dephospho-CoA kinase YP_808679.1 634275 D 272622 CDS YP_808680.1 116511464 4433605 634937..636154 1 NC_008527.1 major facilitator superfamily permease 636154 4433605 LACR_0693 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_808680.1 634937 D 272622 CDS YP_808681.1 116511465 4433606 636151..636297 1 NC_008527.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 636297 rpmG 4433606 rpmG Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L33 YP_808681.1 636151 D 272622 CDS YP_808682.1 116511466 4433607 636675..637937 1 NC_008527.1 cell division membrane protein 637937 4433607 LACR_0695 Lactococcus lactis subsp. cremoris SK11 cell division membrane protein YP_808682.1 636675 D 272622 CDS YP_808683.1 116511467 4433608 638042..641455 1 NC_008527.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 641455 4433608 LACR_0696 Lactococcus lactis subsp. cremoris SK11 pyruvate carboxylase YP_808683.1 638042 D 272622 CDS YP_808684.1 116511468 4432930 645468..646706 1 NC_008527.1 isocitrate dehydrogenase 646706 4432930 LACR_0699 Lactococcus lactis subsp. cremoris SK11 isocitrate dehydrogenase YP_808684.1 645468 D 272622 CDS YP_808685.1 116511469 4432931 complement(646746..647345) 1 NC_008527.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 647345 clpP 4432931 clpP Lactococcus lactis subsp. cremoris SK11 ATP-dependent Clp protease proteolytic subunit YP_808685.1 646746 R 272622 CDS YP_808686.1 116511470 4432932 647542..648072 1 NC_008527.1 hypothetical protein 648072 4432932 LACR_0701 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808686.1 647542 D 272622 CDS YP_808687.1 116511471 4432933 648242..648640 1 NC_008527.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 648640 spxA 4432933 spxA Lactococcus lactis subsp. cremoris SK11 transcriptional regulator Spx YP_808687.1 648242 D 272622 CDS YP_808689.1 116511473 4432935 complement(648941..650104) 1 NC_008527.1 hypothetical protein 650104 4432935 LACR_0704 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808689.1 648941 R 272622 CDS YP_808690.1 116511474 4432936 complement(650161..651336) 1 NC_008527.1 transposase 651336 4432936 LACR_0705 Lactococcus lactis subsp. cremoris SK11 transposase YP_808690.1 650161 R 272622 CDS YP_808691.1 116511475 4432938 654490..654750 1 NC_008527.1 transposase 654750 4432938 LACR_0707 Lactococcus lactis subsp. cremoris SK11 transposase YP_808691.1 654490 D 272622 CDS YP_808692.1 116511476 4432939 654747..655601 1 NC_008527.1 transposase 655601 4432939 LACR_0708 Lactococcus lactis subsp. cremoris SK11 transposase YP_808692.1 654747 D 272622 CDS YP_808693.1 116511477 4432940 655769..655915 1 NC_008527.1 hypothetical protein 655915 4432940 LACR_0709 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808693.1 655769 D 272622 CDS YP_808694.1 116511478 4432941 656022..656912 1 NC_008527.1 transposase 656912 4432941 LACR_0710 Lactococcus lactis subsp. cremoris SK11 transposase YP_808694.1 656022 D 272622 CDS YP_808695.1 116511479 4432942 657127..658074 1 NC_008527.1 xylanase/chitin deacetylase 658074 4432942 LACR_0711 Lactococcus lactis subsp. cremoris SK11 xylanase/chitin deacetylase YP_808695.1 657127 D 272622 CDS YP_808696.1 116511480 4432943 complement(658161..659510) 1 NC_008527.1 branched-chain amino acid permease 659510 4432943 LACR_0712 Lactococcus lactis subsp. cremoris SK11 branched-chain amino acid permease YP_808696.1 658161 R 272622 CDS YP_808697.1 116511481 4432944 complement(659727..659999) 1 NC_008527.1 acetyltransferase 659999 4432944 LACR_0713 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808697.1 659727 R 272622 CDS YP_808698.1 116511482 4432945 complement(660003..660272) 1 NC_008527.1 hypothetical protein 660272 4432945 LACR_0714 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808698.1 660003 R 272622 CDS YP_808699.1 116511483 4432946 660726..661502 1 NC_008527.1 Mg-dependent DNase 661502 4432946 LACR_0715 Lactococcus lactis subsp. cremoris SK11 Mg-dependent DNase YP_808699.1 660726 D 272622 CDS YP_808700.1 116511484 4432947 661536..662069 1 NC_008527.1 adenylate kinase-like kinase 662069 4432947 LACR_0716 Lactococcus lactis subsp. cremoris SK11 adenylate kinase-like kinase YP_808700.1 661536 D 272622 CDS YP_808701.1 116511485 4432798 662047..662607 1 NC_008527.1 hypothetical protein 662607 4432798 LACR_0717 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808701.1 662047 D 272622 CDS YP_808702.1 116511486 4432799 662737..663621 1 NC_008527.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 663621 ksgA 4432799 ksgA Lactococcus lactis subsp. cremoris SK11 dimethyladenosine transferase YP_808702.1 662737 D 272622 CDS YP_808703.1 116511487 4432800 663729..664787 1 NC_008527.1 aminopeptidase P 664787 4432800 LACR_0719 Lactococcus lactis subsp. cremoris SK11 aminopeptidase P YP_808703.1 663729 D 272622 CDS YP_808704.1 116511488 4432801 664919..665476 1 NC_008527.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 665476 4432801 LACR_0720 Lactococcus lactis subsp. cremoris SK11 elongation factor P YP_808704.1 664919 D 272622 CDS YP_808705.1 116511489 4432802 665623..666024 1 NC_008527.1 hypothetical protein 666024 4432802 LACR_0721 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808705.1 665623 D 272622 CDS YP_808706.1 116511490 4432803 666017..666994 1 NC_008527.1 transcription termination factor 666994 4432803 LACR_0722 Lactococcus lactis subsp. cremoris SK11 transcription termination factor YP_808706.1 666017 D 272622 CDS YP_808707.1 116511491 4432804 667218..669221 1 NC_008527.1 4-alpha-glucanotransferase 669221 4432804 LACR_0723 Lactococcus lactis subsp. cremoris SK11 4-alpha-glucanotransferase YP_808707.1 667218 D 272622 CDS YP_808708.1 116511492 4432805 669321..670463 1 NC_008527.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 670463 glgC 4432805 glgC Lactococcus lactis subsp. cremoris SK11 glucose-1-phosphate adenylyltransferase YP_808708.1 669321 D 272622 CDS YP_808709.1 116511493 4432807 671646..673124 1 NC_008527.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 673124 glgA 4432807 glgA Lactococcus lactis subsp. cremoris SK11 glycogen synthase YP_808709.1 671646 D 272622 CDS YP_808710.1 116511494 4432808 673208..675610 1 NC_008527.1 glycogen phosphorylase 675610 4432808 LACR_0727 Lactococcus lactis subsp. cremoris SK11 glycogen phosphorylase YP_808710.1 673208 D 272622 CDS YP_808711.1 116511495 4432809 complement(675615..676505) 1 NC_008527.1 transposase 676505 4432809 LACR_0728 Lactococcus lactis subsp. cremoris SK11 transposase YP_808711.1 675615 R 272622 CDS YP_808712.1 116511496 4432810 676847..678649 1 NC_008527.1 amylopullulanase 678649 4432810 LACR_0729 Lactococcus lactis subsp. cremoris SK11 amylopullulanase YP_808712.1 676847 D 272622 CDS YP_808713.1 116511497 4432811 678725..678982 1 NC_008527.1 XRE family transcriptional regulator 678982 4432811 LACR_0730 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_808713.1 678725 D 272622 CDS YP_808714.1 116511498 4432812 679082..679231 1 NC_008527.1 hypothetical protein 679231 4432812 LACR_0731 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808714.1 679082 D 272622 CDS YP_808715.1 116511499 4432813 679251..679949 1 NC_008527.1 metal-dependent membrane protease 679949 4432813 LACR_0732 Lactococcus lactis subsp. cremoris SK11 metal-dependent membrane protease YP_808715.1 679251 D 272622 CDS YP_808716.1 116511500 4432814 complement(680140..680994) 1 NC_008527.1 transposase 680994 4432814 LACR_0733 Lactococcus lactis subsp. cremoris SK11 transposase YP_808716.1 680140 R 272622 CDS YP_808717.1 116511501 4432209 681110..682603 1 NC_008527.1 di-/tripeptide transporter 682603 4432209 LACR_0734 Lactococcus lactis subsp. cremoris SK11 di-/tripeptide transporter YP_808717.1 681110 D 272622 CDS YP_808718.1 116511502 4432210 682755..683012 1 NC_008527.1 hypothetical protein 683012 4432210 LACR_0735 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808718.1 682755 D 272622 CDS YP_808719.1 116511503 4432211 683009..683152 1 NC_008527.1 hypothetical protein 683152 4432211 LACR_0736 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808719.1 683009 D 272622 CDS YP_808720.1 116511504 4432212 683324..684799 1 NC_008527.1 cytochrome bd-type quinol oxidase, subunit 1 684799 4432212 LACR_0737 Lactococcus lactis subsp. cremoris SK11 cytochrome bd-type quinol oxidase, subunit 1 YP_808720.1 683324 D 272622 CDS YP_808721.1 116511505 4432213 684799..685794 1 NC_008527.1 cytochrome bd-type quinol oxidase, subunit 2 685794 4432213 LACR_0738 Lactococcus lactis subsp. cremoris SK11 cytochrome bd-type quinol oxidase, subunit 2 YP_808721.1 684799 D 272622 CDS YP_808722.1 116511506 4432214 686059..687768 1 NC_008527.1 cytochrome D ABC transporter ATP binding and permease protein 687768 4432214 LACR_0739 Lactococcus lactis subsp. cremoris SK11 cytochrome D ABC transporter ATP binding and permease protein YP_808722.1 686059 D 272622 CDS YP_808723.1 116511507 4432215 687768..689489 1 NC_008527.1 cytochrome D ABC transporter ATP binding and permease protein 689489 4432215 LACR_0740 Lactococcus lactis subsp. cremoris SK11 cytochrome D ABC transporter ATP binding and permease protein YP_808723.1 687768 D 272622 CDS YP_808724.1 116511508 4432216 689692..689805 1 NC_008527.1 hypothetical protein 689805 4432216 LACR_0741 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808724.1 689692 D 272622 CDS YP_808725.1 116511509 4432217 689823..690701 1 NC_008527.1 transcriptional regulator 690701 4432217 LACR_0742 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808725.1 689823 D 272622 CDS YP_808726.1 116511510 4432218 690728..691216 1 NC_008527.1 flavodoxin 691216 4432218 LACR_0743 Lactococcus lactis subsp. cremoris SK11 flavodoxin YP_808726.1 690728 D 272622 CDS YP_808727.1 116511511 4432219 691364..691906 1 NC_008527.1 lysophospholipase L1 related esterase 691906 4432219 LACR_0744 Lactococcus lactis subsp. cremoris SK11 lysophospholipase L1 related esterase YP_808727.1 691364 D 272622 CDS YP_808728.1 116511512 4432221 complement(693744..694400) 1 NC_008527.1 hypothetical protein 694400 4432221 LACR_0746 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808728.1 693744 R 272622 CDS YP_808729.1 116511513 4432222 complement(694474..695118) 1 NC_008527.1 alkaline phosphatase 695118 4432222 LACR_0747 Lactococcus lactis subsp. cremoris SK11 alkaline phosphatase YP_808729.1 694474 R 272622 CDS YP_808730.1 116511514 4432223 complement(695393..697387) 1 NC_008527.1 ABC transporter permease/ATP-binding protein 697387 4432223 LACR_0748 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease/ATP-binding protein YP_808730.1 695393 R 272622 CDS YP_808731.1 116511515 4432224 complement(697493..697711) 1 NC_008527.1 nucleic acid-binding protein 697711 4432224 LACR_0749 Lactococcus lactis subsp. cremoris SK11 nucleic acid-binding protein YP_808731.1 697493 R 272622 CDS YP_808732.1 116511516 4432225 697922..698584 1 NC_008527.1 hypothetical protein 698584 4432225 LACR_0750 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808732.1 697922 D 272622 CDS YP_808733.1 116511517 4432226 complement(698613..699599) 1 NC_008527.1 quinone oxidoreductase 699599 4432226 LACR_0751 Lactococcus lactis subsp. cremoris SK11 quinone oxidoreductase YP_808733.1 698613 R 272622 CDS YP_808734.1 116511518 4434120 699767..700876 1 NC_008527.1 hypothetical protein 700876 4434120 LACR_0752 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808734.1 699767 D 272622 CDS YP_808735.1 116511519 4434122 701216..701416 1 NC_008527.1 hypothetical protein 701416 4434122 LACR_0754 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808735.1 701216 D 272622 CDS YP_808736.1 116511520 4434123 701539..701739 1 NC_008527.1 cold-shock DNA-binding protein family protein 701739 4434123 LACR_0755 Lactococcus lactis subsp. cremoris SK11 cold-shock DNA-binding protein family protein YP_808736.1 701539 D 272622 CDS YP_808737.1 116511521 4434124 702007..702207 1 NC_008527.1 cold-shock DNA-binding protein family protein 702207 4434124 LACR_0756 Lactococcus lactis subsp. cremoris SK11 cold-shock DNA-binding protein family protein YP_808737.1 702007 D 272622 CDS YP_808738.1 116511522 4434125 702533..703285 1 NC_008527.1 beta-lactamase superfamily hydrolase 703285 4434125 LACR_0757 Lactococcus lactis subsp. cremoris SK11 beta-lactamase superfamily hydrolase YP_808738.1 702533 D 272622 CDS YP_808739.1 116511523 4434126 703273..703821 1 NC_008527.1 hypothetical protein 703821 4434126 LACR_0758 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808739.1 703273 D 272622 CDS YP_808740.1 116511524 4434128 704123..704590 1 NC_008527.1 hypothetical protein 704590 4434128 LACR_0760 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808740.1 704123 D 272622 CDS YP_808741.1 116511525 4434129 705513..706463 1 NC_008527.1 ABC-type polysaccharide transport system, permease component 706463 4434129 LACR_0761 Lactococcus lactis subsp. cremoris SK11 ABC-type polysaccharide transport system, permease component YP_808741.1 705513 D 272622 CDS YP_808742.1 116511526 4434130 706475..707377 1 NC_008527.1 ABC-type sugar transport system, permease component 707377 4434130 LACR_0762 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, permease component YP_808742.1 706475 D 272622 CDS YP_808743.1 116511527 4434131 707440..709002 1 NC_008527.1 ABC-type sugar transport system, periplasmic component 709002 4434131 LACR_0763 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, periplasmic component YP_808743.1 707440 D 272622 CDS YP_808744.1 116511528 4434132 709089..709721 1 NC_008527.1 integral membrane protein 709721 4434132 LACR_0764 Lactococcus lactis subsp. cremoris SK11 integral membrane protein YP_808744.1 709089 D 272622 CDS YP_808745.1 116511529 4434133 709748..711967 1 NC_008527.1 alpha-glucosidase 711967 4434133 LACR_0765 Lactococcus lactis subsp. cremoris SK11 alpha-glucosidase YP_808745.1 709748 D 272622 CDS YP_808746.1 116511530 4434134 712036..713043 1 NC_008527.1 LacI family transcription regulator 713043 4434134 LACR_0766 Lactococcus lactis subsp. cremoris SK11 LacI family transcription regulator YP_808746.1 712036 D 272622 CDS YP_808747.1 116511531 4434135 complement(713051..713461) 1 NC_008527.1 hypothetical protein 713461 4434135 LACR_0767 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808747.1 713051 R 272622 CDS YP_808748.1 116511532 4432878 complement(713683..713850) 1 NC_008527.1 hypothetical protein 713850 4432878 LACR_0768 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808748.1 713683 R 272622 CDS YP_808749.1 116511533 4432879 complement(713847..714959) 1 NC_008527.1 O-succinylbenzoate synthase 714959 4432879 LACR_0769 Lactococcus lactis subsp. cremoris SK11 O-succinylbenzoate synthase YP_808749.1 713847 R 272622 CDS YP_808750.1 116511534 4432880 complement(714956..716311) 1 NC_008527.1 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II 716311 4432880 LACR_0770 Lactococcus lactis subsp. cremoris SK11 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II YP_808750.1 714956 R 272622 CDS YP_808751.1 116511535 4432881 complement(716469..717311) 1 NC_008527.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 717311 4432881 LACR_0771 Lactococcus lactis subsp. cremoris SK11 naphthoate synthase YP_808751.1 716469 R 272622 CDS YP_808752.1 116511536 4432882 complement(717824..718639) 1 NC_008527.1 alpha/beta fold family hydrolase 718639 4432882 LACR_0772 Lactococcus lactis subsp. cremoris SK11 alpha/beta fold family hydrolase YP_808752.1 717824 R 272622 CDS YP_808753.1 116511537 4432883 complement(718629..720293) 1 NC_008527.1 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase 720293 4432883 LACR_0773 Lactococcus lactis subsp. cremoris SK11 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase YP_808753.1 718629 R 272622 CDS YP_808754.1 116511538 4432884 complement(720335..721474) 1 NC_008527.1 menaquinone-specific isochorismate synthase 721474 4432884 LACR_0774 Lactococcus lactis subsp. cremoris SK11 menaquinone-specific isochorismate synthase YP_808754.1 720335 R 272622 CDS YP_808755.1 116511539 4432885 721739..722299 1 NC_008527.1 SSU ribosomal protein S5P alanine acetyltransferase 722299 4432885 LACR_0775 Lactococcus lactis subsp. cremoris SK11 SSU ribosomal protein S5P alanine acetyltransferase YP_808755.1 721739 D 272622 CDS YP_808756.1 116511540 4432886 722306..723565 1 NC_008527.1 transcription regulator 723565 4432886 LACR_0776 Lactococcus lactis subsp. cremoris SK11 transcription regulator YP_808756.1 722306 D 272622 CDS YP_808757.1 116511541 4432887 723680..724603 1 NC_008527.1 hypothetical protein 724603 4432887 LACR_0777 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808757.1 723680 D 272622 CDS YP_808758.1 116511542 4432888 complement(724617..725009) 1 NC_008527.1 hypothetical protein 725009 4432888 LACR_0778 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808758.1 724617 R 272622 CDS YP_808759.1 116511543 4432889 complement(725050..726018) 1 NC_008527.1 L-asparaginase 726018 4432889 LACR_0779 Lactococcus lactis subsp. cremoris SK11 L-asparaginase YP_808759.1 725050 R 272622 CDS YP_808760.1 116511544 4432890 726213..727601 1 NC_008527.1 hypothetical protein 727601 4432890 LACR_0780 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808760.1 726213 D 272622 CDS YP_808761.1 116511545 4432891 727688..728032 1 NC_008527.1 hypothetical protein 728032 4432891 LACR_0781 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808761.1 727688 D 272622 CDS YP_808762.1 116511546 4432892 728093..729604 1 NC_008527.1 membrane protease family stomatin/prohibitin-like protein 729604 4432892 LACR_0782 Lactococcus lactis subsp. cremoris SK11 membrane protease family stomatin/prohibitin-like protein YP_808762.1 728093 D 272622 CDS YP_808763.1 116511547 4432893 complement(729641..730993) 1 NC_008527.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 730993 4432893 LACR_0783 Lactococcus lactis subsp. cremoris SK11 aspartate kinase YP_808763.1 729641 R 272622 CDS YP_808764.1 116511548 4432895 complement(731639..732076) 1 NC_008527.1 alpha-beta hydrolase family esterase 732076 4432895 LACR_0785 Lactococcus lactis subsp. cremoris SK11 alpha-beta hydrolase family esterase YP_808764.1 731639 R 272622 CDS YP_808765.1 116511549 4432345 complement(732073..732540) 1 NC_008527.1 MarR family transcriptional regulator 732540 4432345 LACR_0786 Lactococcus lactis subsp. cremoris SK11 MarR family transcriptional regulator YP_808765.1 732073 R 272622 CDS YP_808766.1 116511550 4432346 732633..733337 1 NC_008527.1 HAD family sugar phosphatase 733337 4432346 LACR_0787 Lactococcus lactis subsp. cremoris SK11 HAD family sugar phosphatase YP_808766.1 732633 D 272622 CDS YP_808767.1 116511551 4432347 733430..735394 1 NC_008527.1 signal protein 735394 4432347 LACR_0788 Lactococcus lactis subsp. cremoris SK11 signal protein YP_808767.1 733430 D 272622 CDS YP_808768.1 116511552 4432348 735391..735843 1 NC_008527.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 735843 rplI 4432348 rplI Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L9 YP_808768.1 735391 D 272622 CDS YP_808769.1 116511553 4432349 735849..737216 1 NC_008527.1 primary replicative DNA helicase 737216 4432349 LACR_0790 Lactococcus lactis subsp. cremoris SK11 primary replicative DNA helicase YP_808769.1 735849 D 272622 CDS YP_808770.1 116511554 4432350 737440..737697 1 NC_008527.1 hypothetical protein 737697 4432350 LACR_0791 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808770.1 737440 D 272622 CDS YP_808771.1 116511555 4432351 737766..738539 1 NC_008527.1 choline kinase 738539 4432351 LACR_0792 Lactococcus lactis subsp. cremoris SK11 choline kinase YP_808771.1 737766 D 272622 CDS YP_808772.1 116511556 4432352 738665..739318 1 NC_008527.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 739318 trmB 4432352 trmB Lactococcus lactis subsp. cremoris SK11 tRNA (guanine-N(7)-)-methyltransferase YP_808772.1 738665 D 272622 CDS YP_808773.1 116511557 4432353 739507..739953 1 NC_008527.1 transcriptional regulator NrdR 739953 nrdR 4432353 nrdR Lactococcus lactis subsp. cremoris SK11 transcriptional regulator NrdR YP_808773.1 739507 D 272622 CDS YP_808774.1 116511558 4432354 740060..741211 1 NC_008527.1 replicative DNA helicase loader DnaB 741211 4432354 LACR_0795 Lactococcus lactis subsp. cremoris SK11 replicative DNA helicase loader DnaB YP_808774.1 740060 D 272622 CDS YP_808775.1 116511559 4432355 741211..742092 1 NC_008527.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 742092 4432355 LACR_0796 Lactococcus lactis subsp. cremoris SK11 primosomal protein DnaI YP_808775.1 741211 D 272622 CDS YP_808776.1 116511560 4432356 742085..742807 1 NC_008527.1 nitroreductase 742807 4432356 LACR_0797 Lactococcus lactis subsp. cremoris SK11 nitroreductase YP_808776.1 742085 D 272622 CDS YP_808777.1 116511561 4432357 742914..743429 1 NC_008527.1 hypothetical protein 743429 4432357 LACR_0798 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808777.1 742914 D 272622 CDS YP_808778.1 116511562 4432358 743541..744851 1 NC_008527.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 744851 engA 4432358 engA Lactococcus lactis subsp. cremoris SK11 GTP-binding protein EngA YP_808778.1 743541 D 272622 CDS YP_808779.1 116511563 4432359 744959..745504 1 NC_008527.1 XRE family transcriptional regulator 745504 4432359 LACR_0800 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_808779.1 744959 D 272622 CDS YP_808780.1 116511564 4432360 745561..746451 1 NC_008527.1 transposase 746451 4432360 LACR_0801 Lactococcus lactis subsp. cremoris SK11 transposase YP_808780.1 745561 D 272622 CDS YP_808781.1 116511565 4433106 747244..748650 1 NC_008527.1 hypothetical protein 748650 4433106 LACR_0803 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808781.1 747244 D 272622 CDS YP_808782.1 116511566 4433107 748771..750648 1 NC_008527.1 hypothetical protein 750648 4433107 LACR_0804 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808782.1 748771 D 272622 CDS YP_808783.1 116511567 4433108 750760..752583 1 NC_008527.1 hypothetical protein 752583 4433108 LACR_0805 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808783.1 750760 D 272622 CDS YP_808784.1 116511568 4433110 752967..753716 1 NC_008527.1 sortase (surface protein transpeptidase) 753716 4433110 LACR_0807 Lactococcus lactis subsp. cremoris SK11 sortase (surface protein transpeptidase) YP_808784.1 752967 D 272622 CDS YP_808785.1 116511569 4433112 753917..754315 1 NC_008527.1 hypothetical protein 754315 4433112 LACR_0809 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808785.1 753917 D 272622 CDS YP_808786.1 116511570 4433114 complement(754724..755422) 1 NC_008527.1 putative effector of murein hydrolase 755422 4433114 LACR_0811 Lactococcus lactis subsp. cremoris SK11 putative effector of murein hydrolase YP_808786.1 754724 R 272622 CDS YP_808787.1 116511571 4433115 complement(755441..755845) 1 NC_008527.1 putative effector of murein hydrolase LrgA 755845 4433115 LACR_0812 Lactococcus lactis subsp. cremoris SK11 putative effector of murein hydrolase LrgA YP_808787.1 755441 R 272622 CDS YP_808788.1 116511572 4433116 756119..756592 1 NC_008527.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 756592 4433116 LACR_0813 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808788.1 756119 D 272622 CDS YP_808789.1 116511573 4433117 756760..757908 1 NC_008527.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 757908 nusA 4433117 nusA Lactococcus lactis subsp. cremoris SK11 transcription elongation factor NusA YP_808789.1 756760 D 272622 CDS YP_808790.1 116511574 4433118 758073..758399 1 NC_008527.1 hypothetical protein 758399 4433118 LACR_0815 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808790.1 758073 D 272622 CDS YP_808791.1 116511575 4433119 758402..758707 1 NC_008527.1 hypothetical protein 758707 4433119 LACR_0816 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808791.1 758402 D 272622 CDS YP_808792.1 116511576 4433120 758728..761580 1 NC_008527.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 761580 infB 4433120 infB Lactococcus lactis subsp. cremoris SK11 translation initiation factor IF-2 YP_808792.1 758728 D 272622 CDS YP_808793.1 116511577 4433121 761825..762184 1 NC_008527.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 762184 rbfA 4433121 rbfA Lactococcus lactis subsp. cremoris SK11 ribosome-binding factor A YP_808793.1 761825 D 272622 CDS YP_808794.1 116511578 4433122 762359..763306 1 NC_008527.1 mannose-6-phosphate isomerase 763306 4433122 LACR_0819 Lactococcus lactis subsp. cremoris SK11 mannose-6-phosphate isomerase YP_808794.1 762359 D 272622 CDS YP_808795.1 116511579 4433123 763684..764124 1 NC_008527.1 MarR family transcriptional regulator 764124 4433123 LACR_0820 Lactococcus lactis subsp. cremoris SK11 MarR family transcriptional regulator YP_808795.1 763684 D 272622 CDS YP_808796.1 116511580 4432362 764124..765101 1 NC_008527.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 765101 4432362 LACR_0821 Lactococcus lactis subsp. cremoris SK11 3-oxoacyl-ACP synthase YP_808796.1 764124 D 272622 CDS YP_808797.1 116511581 4432363 765283..765504 1 NC_008527.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 765504 acpP 4432363 acpP Lactococcus lactis subsp. cremoris SK11 acyl carrier protein YP_808797.1 765283 D 272622 CDS YP_808798.1 116511582 4432364 765790..766710 1 NC_008527.1 ACP S-malonyltransferase 766710 4432364 LACR_0823 Lactococcus lactis subsp. cremoris SK11 ACP S-malonyltransferase YP_808798.1 765790 D 272622 CDS YP_808799.1 116511583 4432365 766848..767579 1 NC_008527.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 767579 fabG 4432365 fabG Lactococcus lactis subsp. cremoris SK11 3-ketoacyl-ACP reductase YP_808799.1 766848 D 272622 CDS YP_808800.1 116511584 4432366 767621..768856 1 NC_008527.1 3-oxoacyl-ACP synthase 768856 4432366 LACR_0825 Lactococcus lactis subsp. cremoris SK11 3-oxoacyl-ACP synthase YP_808800.1 767621 D 272622 CDS YP_808801.1 116511585 4432367 768918..769385 1 NC_008527.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 769385 4432367 LACR_0826 Lactococcus lactis subsp. cremoris SK11 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_808801.1 768918 D 272622 CDS YP_808802.1 116511586 4432368 769506..769940 1 NC_008527.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 769940 fabZ 4432368 fabZ Lactococcus lactis subsp. cremoris SK11 (3R)-hydroxymyristoyl-ACP dehydratase YP_808802.1 769506 D 272622 CDS YP_808803.1 116511587 4432369 770149..771516 1 NC_008527.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 771516 4432369 LACR_0828 Lactococcus lactis subsp. cremoris SK11 acetyl-CoA carboxylase biotin carboxylase subunit YP_808803.1 770149 D 272622 CDS YP_808804.1 116511588 4432370 771591..772457 1 NC_008527.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 772457 4432370 LACR_0829 Lactococcus lactis subsp. cremoris SK11 acetyl-CoA carboxylase subunit beta YP_808804.1 771591 D 272622 CDS YP_808805.1 116511589 4432371 772450..773244 1 NC_008527.1 acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha 773244 4432371 LACR_0830 Lactococcus lactis subsp. cremoris SK11 acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha YP_808805.1 772450 D 272622 CDS YP_808806.1 116511590 4432372 773421..774563 1 NC_008527.1 catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase 774563 4432372 LACR_0831 Lactococcus lactis subsp. cremoris SK11 cystathionine gamma-synthase YP_808806.1 773421 D 272622 CDS YP_808807.1 116511591 4432373 774756..775676 1 NC_008527.1 cystathionine beta-synthase (acetylserine-dependent) 775676 4432373 LACR_0832 Lactococcus lactis subsp. cremoris SK11 cystathionine beta-synthase (acetylserine-dependent) YP_808807.1 774756 D 272622 CDS YP_808808.1 116511592 4432374 775907..776146 1 NC_008527.1 hypothetical protein 776146 4432374 LACR_0833 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808808.1 775907 D 272622 CDS YP_808809.1 116511593 4432375 776293..776586 1 NC_008527.1 rhodanese-related sulfurtransferase 776586 4432375 LACR_0834 Lactococcus lactis subsp. cremoris SK11 rhodanese-related sulfurtransferase YP_808809.1 776293 D 272622 CDS YP_808810.1 116511594 4432377 776922..778565 1 NC_008527.1 fused NAD(FAD)-dependent dehydrogenase/rhodanese domain-containing protein 778565 4432377 LACR_0836 Lactococcus lactis subsp. cremoris SK11 fused NAD(FAD)-dependent dehydrogenase/rhodanese domain-containing protein YP_808810.1 776922 D 272622 CDS YP_808811.1 116511595 4432378 778583..778837 1 NC_008527.1 hypothetical protein 778837 4432378 LACR_0837 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808811.1 778583 D 272622 CDS YP_808812.1 116511596 4434268 778966..779316 1 NC_008527.1 arsenate reductase 779316 4434268 LACR_0838 Lactococcus lactis subsp. cremoris SK11 arsenate reductase YP_808812.1 778966 D 272622 CDS YP_808813.1 116511597 4434269 complement(779479..780225) 1 NC_008527.1 sugar metabolism transcriptional regulator 780225 4434269 LACR_0839 Lactococcus lactis subsp. cremoris SK11 sugar metabolism transcriptional regulator YP_808813.1 779479 R 272622 CDS YP_808814.1 116511598 4434270 complement(780319..780876) 1 NC_008527.1 acetyltransferase 780876 4434270 LACR_0840 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808814.1 780319 R 272622 CDS YP_808815.1 116511599 4434271 complement(780966..781823) 1 NC_008527.1 exonuclease III 781823 4434271 LACR_0841 Lactococcus lactis subsp. cremoris SK11 exonuclease III YP_808815.1 780966 R 272622 CDS YP_808816.1 116511600 4434272 782625..784625 1 NC_008527.1 methionyl-tRNA synthetase 784625 4434272 LACR_0842 Lactococcus lactis subsp. cremoris SK11 methionyl-tRNA synthetase YP_808816.1 782625 D 272622 CDS YP_808817.1 116511601 4434273 784834..784962 1 NC_008527.1 hypothetical protein 784962 4434273 LACR_0843 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808817.1 784834 D 272622 CDS YP_808818.1 116511602 4434274 785202..785441 1 NC_008527.1 hypothetical protein 785441 4434274 LACR_0844 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808818.1 785202 D 272622 CDS YP_808819.1 116511603 4434275 785463..786194 1 NC_008527.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 786194 fabG 4434275 fabG Lactococcus lactis subsp. cremoris SK11 3-ketoacyl-ACP reductase YP_808819.1 785463 D 272622 CDS YP_808820.1 116511604 4434276 complement(786187..786366) 1 NC_008527.1 hypothetical protein 786366 4434276 LACR_0846 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808820.1 786187 R 272622 CDS YP_808821.1 116511605 4434277 786599..787108 1 NC_008527.1 hypothetical protein 787108 4434277 LACR_0847 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808821.1 786599 D 272622 CDS YP_808822.1 116511606 4434278 787211..787792 1 NC_008527.1 putative NADH-flavin reductase 787792 4434278 LACR_0848 Lactococcus lactis subsp. cremoris SK11 putative NADH-flavin reductase YP_808822.1 787211 D 272622 CDS YP_808823.1 116511607 4434279 787998..788288 1 NC_008527.1 transposase 788288 4434279 LACR_0849 Lactococcus lactis subsp. cremoris SK11 transposase YP_808823.1 787998 D 272622 CDS YP_808824.1 116511608 4434280 788306..789145 1 NC_008527.1 transposase 789145 4434280 LACR_0850 Lactococcus lactis subsp. cremoris SK11 transposase YP_808824.1 788306 D 272622 CDS YP_808825.1 116511609 4434282 complement(789402..789947) 1 NC_008527.1 transposase 789947 4434282 LACR_0852 Lactococcus lactis subsp. cremoris SK11 transposase YP_808825.1 789402 R 272622 CDS YP_808826.1 116511610 4434283 complement(790019..790600) 1 NC_008527.1 transposase 790600 4434283 LACR_0853 Lactococcus lactis subsp. cremoris SK11 transposase YP_808826.1 790019 R 272622 CDS YP_808827.1 116511611 4434284 complement(790654..791493) 1 NC_008527.1 transposase 791493 4434284 LACR_0854 Lactococcus lactis subsp. cremoris SK11 transposase YP_808827.1 790654 R 272622 CDS YP_808828.1 116511612 4434285 complement(791511..791801) 1 NC_008527.1 transposase 791801 4434285 LACR_0855 Lactococcus lactis subsp. cremoris SK11 transposase YP_808828.1 791511 R 272622 CDS YP_808829.1 116511613 4433124 792015..793037 1 NC_008527.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 793037 argC 4433124 argC Lactococcus lactis subsp. cremoris SK11 N-acetyl-gamma-glutamyl-phosphate reductase YP_808829.1 792015 D 272622 CDS YP_808830.1 116511614 4433125 793049..794236 1 NC_008527.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 794236 argJ 4433125 argJ Lactococcus lactis subsp. cremoris SK11 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_808830.1 793049 D 272622 CDS YP_808831.1 116511615 4433126 794254..795387 1 NC_008527.1 acetylornithine aminotransferase 795387 argD 4433126 argD Lactococcus lactis subsp. cremoris SK11 acetylornithine aminotransferase YP_808831.1 794254 D 272622 CDS YP_808832.1 116511616 4433127 795384..796235 1 NC_008527.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 796235 4433127 LACR_0859 Lactococcus lactis subsp. cremoris SK11 acetylglutamate kinase YP_808832.1 795384 D 272622 CDS YP_808833.1 116511617 4433128 796274..797275 1 NC_008527.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 797275 4433128 LACR_0860 Lactococcus lactis subsp. cremoris SK11 ornithine carbamoyltransferase YP_808833.1 796274 D 272622 CDS YP_808834.1 116511618 4433129 797299..797871 1 NC_008527.1 hypothetical protein 797871 4433129 LACR_0861 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808834.1 797299 D 272622 CDS YP_808835.1 116511619 4433130 798050..798745 1 NC_008527.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 798745 rnc 4433130 rnc Lactococcus lactis subsp. cremoris SK11 ribonuclease III YP_808835.1 798050 D 272622 CDS YP_808836.1 116511620 4433131 798735..802259 1 NC_008527.1 condensin subunit Smc 802259 4433131 LACR_0863 Lactococcus lactis subsp. cremoris SK11 condensin subunit Smc YP_808836.1 798735 D 272622 CDS YP_808837.1 116511621 4433132 802501..804669 1 NC_008527.1 phosphoglycerol transferase/alkaline phosphatase superfamily protein 804669 4433132 LACR_0864 Lactococcus lactis subsp. cremoris SK11 phosphoglycerol transferase/alkaline phosphatase superfamily protein YP_808837.1 802501 D 272622 CDS YP_808838.1 116511622 4433133 804764..805174 1 NC_008527.1 hypothetical protein 805174 4433133 LACR_0865 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808838.1 804764 D 272622 CDS YP_808839.1 116511623 4433134 805267..806385 1 NC_008527.1 hypothetical protein 806385 4433134 LACR_0866 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808839.1 805267 D 272622 CDS YP_808840.1 116511624 4433135 806382..807143 1 NC_008527.1 hypothetical protein 807143 4433135 LACR_0867 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808840.1 806382 D 272622 CDS YP_808841.1 116511625 4433136 complement(807193..808533) 1 NC_008527.1 amino acid permease 808533 4433136 LACR_0868 Lactococcus lactis subsp. cremoris SK11 amino acid permease YP_808841.1 807193 R 272622 CDS YP_808842.1 116511626 4433137 complement(808693..808860) 1 NC_008527.1 hypothetical protein 808860 4433137 LACR_0869 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808842.1 808693 R 272622 CDS YP_808843.1 116511627 4433138 808863..809708 1 NC_008527.1 HAD superfamily hydrolase 809708 4433138 LACR_0870 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_808843.1 808863 D 272622 CDS YP_808844.1 116511628 4433139 809718..810269 1 NC_008527.1 hypothetical protein 810269 4433139 LACR_0871 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808844.1 809718 D 272622 CDS YP_808845.1 116511629 4433306 811907..812881 1 NC_008527.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 812881 4433306 LACR_0873 Lactococcus lactis subsp. cremoris SK11 ribose-phosphate pyrophosphokinase YP_808845.1 811907 D 272622 CDS YP_808846.1 116511630 4433307 813005..813676 1 NC_008527.1 regulator of polyketide synthase expression 813676 4433307 LACR_0874 Lactococcus lactis subsp. cremoris SK11 regulator of polyketide synthase expression YP_808846.1 813005 D 272622 CDS YP_808847.1 116511631 4433308 813747..816236 1 NC_008527.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 816236 leuS 4433308 leuS Lactococcus lactis subsp. cremoris SK11 leucyl-tRNA synthetase YP_808847.1 813747 D 272622 CDS YP_808848.1 116511632 4433309 816480..817235 1 NC_008527.1 transcriptional regulator 817235 4433309 LACR_0876 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808848.1 816480 D 272622 CDS YP_808849.1 116511633 4433311 819163..820527 1 NC_008527.1 beta-glucosidase 820527 4433311 LACR_0878 Lactococcus lactis subsp. cremoris SK11 beta-glucosidase YP_808849.1 819163 D 272622 CDS YP_808850.1 116511634 4433312 820674..821477 1 NC_008527.1 alpha/beta fold family hydrolase 821477 4433312 LACR_0879 Lactococcus lactis subsp. cremoris SK11 alpha/beta fold family hydrolase YP_808850.1 820674 D 272622 CDS YP_808851.1 116511635 4433313 821614..821976 1 NC_008527.1 hypothetical protein 821976 4433313 LACR_0880 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808851.1 821614 D 272622 CDS YP_808852.1 116511636 4433314 822048..822605 1 NC_008527.1 transposase 822605 4433314 LACR_0881 Lactococcus lactis subsp. cremoris SK11 transposase YP_808852.1 822048 D 272622 CDS YP_808853.1 116511637 4433315 822602..823420 1 NC_008527.1 transposase 823420 4433315 LACR_0882 Lactococcus lactis subsp. cremoris SK11 transposase YP_808853.1 822602 D 272622 CDS YP_808854.1 116511638 4433316 823494..823784 1 NC_008527.1 transposase 823784 4433316 LACR_0883 Lactococcus lactis subsp. cremoris SK11 transposase YP_808854.1 823494 D 272622 CDS YP_808855.1 116511639 4433317 823802..824641 1 NC_008527.1 transposase 824641 4433317 LACR_0884 Lactococcus lactis subsp. cremoris SK11 transposase YP_808855.1 823802 D 272622 CDS YP_808856.1 116511640 4433318 824830..826089 1 NC_008527.1 NADH dehydrogenase 826089 4433318 LACR_0885 Lactococcus lactis subsp. cremoris SK11 NADH dehydrogenase YP_808856.1 824830 D 272622 CDS YP_808857.1 116511641 4433319 826230..828236 1 NC_008527.1 NADH dehydrogenase 828236 4433319 LACR_0886 Lactococcus lactis subsp. cremoris SK11 NADH dehydrogenase YP_808857.1 826230 D 272622 CDS YP_808858.1 116511642 4433320 828349..829020 1 NC_008527.1 L-serine ammonia-lyase 829020 4433320 LACR_0887 Lactococcus lactis subsp. cremoris SK11 L-serine ammonia-lyase YP_808858.1 828349 D 272622 CDS YP_808859.1 116511643 4433321 829040..829903 1 NC_008527.1 L-serine ammonia-lyase / 2-hydroxymethylglutarate dehydratase 829903 4433321 LACR_0888 Lactococcus lactis subsp. cremoris SK11 L-serine ammonia-lyase / 2-hydroxymethylglutarate dehydratase YP_808859.1 829040 D 272622 CDS YP_808860.1 116511644 4433322 830024..830479 1 NC_008527.1 transcriptional regulator 830479 4433322 LACR_0889 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808860.1 830024 D 272622 CDS YP_808861.1 116511645 4433323 830498..830698 1 NC_008527.1 mercuric reductase 830698 4433323 LACR_0890 Lactococcus lactis subsp. cremoris SK11 mercuric reductase YP_808861.1 830498 D 272622 CDS YP_808862.1 116511646 4433559 830887..833049 1 NC_008527.1 copper/potassium-transporting ATPase 833049 4433559 LACR_0891 Lactococcus lactis subsp. cremoris SK11 copper/potassium-transporting ATPase YP_808862.1 830887 D 272622 CDS YP_808863.1 116511647 4433560 complement(833115..833261) 1 NC_008527.1 hypothetical protein 833261 4433560 LACR_0892 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808863.1 833115 R 272622 CDS YP_808864.1 116511648 4433561 complement(833251..835902) 1 NC_008527.1 hypothetical protein 835902 4433561 LACR_0893 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808864.1 833251 R 272622 CDS YP_808865.1 116511649 4433562 complement(835973..836758) 1 NC_008527.1 galactose-1-phosphate uridylyltransferase 836758 4433562 LACR_0894 Lactococcus lactis subsp. cremoris SK11 galactose-1-phosphate uridylyltransferase YP_808865.1 835973 R 272622 CDS YP_808866.1 116511650 4433563 837049..838203 1 NC_008527.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 838203 mnmA 4433563 mnmA Lactococcus lactis subsp. cremoris SK11 tRNA-specific 2-thiouridylase MnmA YP_808866.1 837049 D 272622 CDS YP_808867.1 116511651 4433564 838457..839683 1 NC_008527.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 839683 rpsA 4433564 rpsA Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S1 YP_808867.1 838457 D 272622 CDS YP_808868.1 116511652 4433565 839879..841330 1 NC_008527.1 hypothetical protein 841330 4433565 LACR_0897 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808868.1 839879 D 272622 CDS YP_808869.1 116511653 4433566 841413..842117 1 NC_008527.1 DNA-binding response regulator 842117 4433566 LACR_0898 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_808869.1 841413 D 272622 CDS YP_808870.1 116511654 4433567 842266..843414 1 NC_008527.1 Signal transduction histidine kinase 843414 4433567 LACR_0899 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_808870.1 842266 D 272622 CDS YP_808871.1 116511655 4433568 843553..844269 1 NC_008527.1 uridine phosphorylase 844269 4433568 LACR_0900 Lactococcus lactis subsp. cremoris SK11 uridine phosphorylase YP_808871.1 843553 D 272622 CDS YP_808872.1 116511656 4433569 844287..845000 1 NC_008527.1 nicotinamide mononucleotide transporter 845000 4433569 LACR_0901 Lactococcus lactis subsp. cremoris SK11 nicotinamide mononucleotide transporter YP_808872.1 844287 D 272622 CDS YP_808873.1 116511657 4433570 845129..847105 1 NC_008527.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 847105 uvrC 4433570 uvrC Lactococcus lactis subsp. cremoris SK11 excinuclease ABC subunit C YP_808873.1 845129 D 272622 CDS YP_808874.1 116511658 4433571 847203..848363 1 NC_008527.1 A/G-specific adenine glycosylase 848363 4433571 LACR_0903 Lactococcus lactis subsp. cremoris SK11 A/G-specific adenine glycosylase YP_808874.1 847203 D 272622 CDS YP_808875.1 116511659 4433572 849338..849673 1 NC_008527.1 transcriptional regulator 849673 4433572 LACR_0904 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808875.1 849338 D 272622 CDS YP_808876.1 116511660 4433574 850123..850977 1 NC_008527.1 transposase 850977 4433574 LACR_0906 Lactococcus lactis subsp. cremoris SK11 transposase YP_808876.1 850123 D 272622 CDS YP_808877.1 116511661 4433575 complement(851081..851911) 1 NC_008527.1 lipopolysaccharide biosynthesis glycosyltransferase 851911 4433575 LACR_0907 Lactococcus lactis subsp. cremoris SK11 lipopolysaccharide biosynthesis glycosyltransferase YP_808877.1 851081 R 272622 CDS YP_808878.1 116511662 4432071 852217..853635 1 NC_008527.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 853635 4432071 LACR_0908 Lactococcus lactis subsp. cremoris SK11 dipeptidase PepV YP_808878.1 852217 D 272622 CDS YP_808879.1 116511663 4432072 853764..854123 1 NC_008527.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 854123 acpS 4432072 acpS Lactococcus lactis subsp. cremoris SK11 4'-phosphopantetheinyl transferase YP_808879.1 853764 D 272622 CDS YP_808880.1 116511664 4432073 854167..855270 1 NC_008527.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 855270 alr 4432073 alr Lactococcus lactis subsp. cremoris SK11 alanine racemase YP_808880.1 854167 D 272622 CDS YP_808881.1 116511665 4432074 855431..855859 1 NC_008527.1 arsenate reductase 855859 4432074 LACR_0911 Lactococcus lactis subsp. cremoris SK11 arsenate reductase YP_808881.1 855431 D 272622 CDS YP_808882.1 116511666 4432075 855998..857305 1 NC_008527.1 glutathione reductase 857305 4432075 LACR_0912 Lactococcus lactis subsp. cremoris SK11 glutathione reductase YP_808882.1 855998 D 272622 CDS YP_808883.1 116511667 4432076 857434..858351 1 NC_008527.1 choline ABC transporter ATP binding protein 858351 4432076 LACR_0913 Lactococcus lactis subsp. cremoris SK11 choline ABC transporter ATP binding protein YP_808883.1 857434 D 272622 CDS YP_808884.1 116511668 4432077 858348..859850 1 NC_008527.1 choline ABC transporter permease and substrate binding protein 859850 4432077 LACR_0914 Lactococcus lactis subsp. cremoris SK11 choline ABC transporter permease and substrate binding protein YP_808884.1 858348 D 272622 CDS YP_808885.1 116511669 4432078 860112..862538 1 NC_008527.1 hypothetical protein 862538 4432078 LACR_0915 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808885.1 860112 D 272622 CDS YP_808886.1 116511670 4432079 862561..863064 1 NC_008527.1 hypothetical protein 863064 4432079 LACR_0916 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808886.1 862561 D 272622 CDS YP_808887.1 116511671 4432080 863074..863313 1 NC_008527.1 hypothetical protein 863313 4432080 LACR_0917 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808887.1 863074 D 272622 CDS YP_808888.1 116511672 4432081 863466..864044 1 NC_008527.1 hypothetical protein 864044 4432081 LACR_0918 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808888.1 863466 D 272622 CDS YP_808889.1 116511673 4432082 complement(864026..864916) 1 NC_008527.1 transposase 864916 4432082 LACR_0919 Lactococcus lactis subsp. cremoris SK11 transposase YP_808889.1 864026 R 272622 CDS YP_808890.1 116511674 4432083 complement(865105..867147) 1 NC_008527.1 copper-potassium transporting ATPase B 867147 4432083 LACR_0920 Lactococcus lactis subsp. cremoris SK11 copper-potassium transporting ATPase B YP_808890.1 865105 R 272622 CDS YP_808891.1 116511675 4432084 867306..868193 1 NC_008527.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 868193 4432084 LACR_0921 Lactococcus lactis subsp. cremoris SK11 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_808891.1 867306 D 272622 CDS YP_808892.1 116511676 4432085 868349..869617 1 NC_008527.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 869617 xseA 4432085 xseA Lactococcus lactis subsp. cremoris SK11 exodeoxyribonuclease VII large subunit YP_808892.1 868349 D 272622 CDS YP_808893.1 116511677 4432086 869620..869859 1 NC_008527.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 869859 4432086 LACR_0923 Lactococcus lactis subsp. cremoris SK11 exodeoxyribonuclease VII small subunit YP_808893.1 869620 D 272622 CDS YP_808894.1 116511678 4432087 870086..870976 1 NC_008527.1 transposase 870976 4432087 LACR_0924 Lactococcus lactis subsp. cremoris SK11 transposase YP_808894.1 870086 D 272622 CDS YP_808895.1 116511679 4432088 871035..872180 1 NC_008527.1 glycerate kinase 872180 4432088 LACR_0925 Lactococcus lactis subsp. cremoris SK11 glycerate kinase YP_808895.1 871035 D 272622 CDS YP_808896.1 116511680 4433417 872357..873262 1 NC_008527.1 farnesyl-diphosphate synthase 873262 4433417 LACR_0926 Lactococcus lactis subsp. cremoris SK11 farnesyl-diphosphate synthase YP_808896.1 872357 D 272622 CDS YP_808897.1 116511681 4433418 873263..873763 1 NC_008527.1 acetyltransferase 873763 4433418 LACR_0927 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808897.1 873263 D 272622 CDS YP_808898.1 116511682 4433419 873839..874645 1 NC_008527.1 hypothetical protein 874645 4433419 LACR_0928 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808898.1 873839 D 272622 CDS YP_808899.1 116511683 4433420 874642..875088 1 NC_008527.1 ArgR family transcriptional regulator 875088 4433420 LACR_0929 Lactococcus lactis subsp. cremoris SK11 ArgR family transcriptional regulator YP_808899.1 874642 D 272622 CDS YP_808900.1 116511684 4433421 875268..876935 1 NC_008527.1 ATPase for DNA repair 876935 4433421 LACR_0930 Lactococcus lactis subsp. cremoris SK11 ATPase for DNA repair YP_808900.1 875268 D 272622 CDS YP_808901.1 116511685 4433422 877420..877521 1 NC_008527.1 hypothetical protein 877521 4433422 LACR_0931 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808901.1 877420 D 272622 CDS YP_808902.1 116511686 4433423 877637..878203 1 NC_008527.1 hypothetical protein 878203 4433423 LACR_0932 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808902.1 877637 D 272622 CDS YP_808903.1 116511687 4433424 878298..878819 1 NC_008527.1 hypothetical protein 878819 4433424 LACR_0933 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808903.1 878298 D 272622 CDS YP_808904.1 116511688 4433425 878841..879767 1 NC_008527.1 hypothetical protein 879767 4433425 LACR_0934 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808904.1 878841 D 272622 CDS YP_808905.1 116511689 4433426 880056..880952 1 NC_008527.1 S-adenosyl-methyltransferase MraW 880952 mraW 4433426 mraW Lactococcus lactis subsp. cremoris SK11 S-adenosyl-methyltransferase MraW YP_808905.1 880056 D 272622 CDS YP_808906.1 116511690 4433427 881108..881488 1 NC_008527.1 cell division protein FtsL 881488 4433427 LACR_0936 Lactococcus lactis subsp. cremoris SK11 cell division protein FtsL YP_808906.1 881108 D 272622 CDS YP_808907.1 116511691 4433428 881485..883782 1 NC_008527.1 penicillin-binding protein 883782 4433428 LACR_0937 Lactococcus lactis subsp. cremoris SK11 penicillin-binding protein YP_808907.1 881485 D 272622 CDS YP_808908.1 116511692 4433429 883857..884846 1 NC_008527.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 884846 mraY 4433429 mraY Lactococcus lactis subsp. cremoris SK11 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_808908.1 883857 D 272622 CDS YP_808909.1 116511693 4433430 885045..885329 1 NC_008527.1 hypothetical protein 885329 4433430 LACR_0939 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808909.1 885045 D 272622 CDS YP_808910.1 116511694 4433431 885480..886997 1 NC_008527.1 ABC transporter permease 886997 4433431 LACR_0940 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease YP_808910.1 885480 D 272622 CDS YP_808911.1 116511695 4433432 887105..887767 1 NC_008527.1 peptide ABC transporter ATPase 887767 4433432 LACR_0941 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter ATPase YP_808911.1 887105 D 272622 CDS YP_808912.1 116511696 4433433 888127..889014 1 NC_008527.1 malolactic fermentation system transcription activator 889014 4433433 LACR_0942 Lactococcus lactis subsp. cremoris SK11 malolactic fermentation system transcription activator YP_808912.1 888127 D 272622 CDS YP_808913.1 116511697 4432984 889273..890163 1 NC_008527.1 transposase 890163 4432984 LACR_0943 Lactococcus lactis subsp. cremoris SK11 transposase YP_808913.1 889273 D 272622 CDS YP_808914.1 116511698 4432985 890250..890924 1 NC_008527.1 ppGpp synthetase/hydrolase catalytic subunit 890924 4432985 LACR_0944 Lactococcus lactis subsp. cremoris SK11 ppGpp synthetase/hydrolase catalytic subunit YP_808914.1 890250 D 272622 CDS YP_808915.1 116511699 4432986 891084..891428 1 NC_008527.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 891428 rplS 4432986 rplS Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L19 YP_808915.1 891084 D 272622 CDS YP_808916.1 116511700 4432987 complement(891604..892020) 1 NC_008527.1 ketosteroid isomerase related protein 892020 4432987 LACR_0946 Lactococcus lactis subsp. cremoris SK11 ketosteroid isomerase related protein YP_808916.1 891604 R 272622 CDS YP_808917.1 116511701 4432988 complement(892358..892819) 1 NC_008527.1 acetyltransferase 892819 4432988 LACR_0947 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_808917.1 892358 R 272622 CDS YP_808918.1 116511702 4432989 893025..893582 1 NC_008527.1 hypothetical protein 893582 4432989 LACR_0948 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808918.1 893025 D 272622 CDS YP_808919.1 116511703 4432990 893575..894903 1 NC_008527.1 glycosyltransferase 894903 4432990 LACR_0949 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_808919.1 893575 D 272622 CDS YP_808920.1 116511704 4432991 895134..895691 1 NC_008527.1 hypothetical protein 895691 4432991 LACR_0950 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808920.1 895134 D 272622 CDS YP_808921.1 116511705 4432992 complement(895754..895999) 1 NC_008527.1 hypothetical protein 895999 4432992 LACR_0951 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808921.1 895754 R 272622 CDS YP_808922.1 116511706 4432993 896271..896996 1 NC_008527.1 nicotinamide mononucleotide transporter 896996 4432993 LACR_0952 Lactococcus lactis subsp. cremoris SK11 nicotinamide mononucleotide transporter YP_808922.1 896271 D 272622 CDS YP_808923.1 116511707 4432994 complement(897139..897294) 1 NC_008527.1 hypothetical protein 897294 4432994 LACR_0953 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808923.1 897139 R 272622 CDS YP_808924.1 116511708 4432995 897549..897974 1 NC_008527.1 universal stress protein UspA-like nucleotide-binding protein 897974 4432995 LACR_0954 Lactococcus lactis subsp. cremoris SK11 universal stress protein UspA-like nucleotide-binding protein YP_808924.1 897549 D 272622 CDS YP_808925.1 116511709 4432996 898142..898504 1 NC_008527.1 HU-like DNA-binding protein 898504 4432996 LACR_0955 Lactococcus lactis subsp. cremoris SK11 HU-like DNA-binding protein YP_808925.1 898142 D 272622 CDS YP_808926.1 116511710 4432997 complement(898566..899099) 1 NC_008527.1 transcriptional regulator 899099 4432997 LACR_0956 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808926.1 898566 R 272622 CDS YP_808927.1 116511711 4432999 complement(899771..900661) 1 NC_008527.1 transposase 900661 4432999 LACR_0958 Lactococcus lactis subsp. cremoris SK11 transposase YP_808927.1 899771 R 272622 CDS YP_808928.1 116511712 4433000 900796..902667 1 NC_008527.1 hypothetical protein 902667 4433000 LACR_0959 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808928.1 900796 D 272622 CDS YP_808929.1 116511713 4433001 902856..903188 1 NC_008527.1 hypothetical protein 903188 4433001 LACR_0960 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808929.1 902856 D 272622 CDS YP_808930.1 116511714 4433769 904399..905079 1 NC_008527.1 transposase 905079 4433769 LACR_0961 Lactococcus lactis subsp. cremoris SK11 transposase YP_808930.1 904399 D 272622 CDS YP_808931.1 116511715 4433770 905456..905716 1 NC_008527.1 transposase 905716 4433770 LACR_0962 Lactococcus lactis subsp. cremoris SK11 transposase YP_808931.1 905456 D 272622 CDS YP_808932.1 116511716 4433771 905728..906567 1 NC_008527.1 transposase 906567 4433771 LACR_0963 Lactococcus lactis subsp. cremoris SK11 transposase YP_808932.1 905728 D 272622 CDS YP_808933.1 116511717 4433773 907715..908344 1 NC_008527.1 hypothetical protein 908344 4433773 LACR_0965 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808933.1 907715 D 272622 CDS YP_808934.1 116511718 4433774 908341..909339 1 NC_008527.1 Signal transduction histidine kinase 909339 4433774 LACR_0966 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_808934.1 908341 D 272622 CDS YP_808935.1 116511719 4433775 909367..909996 1 NC_008527.1 DNA-binding response regulator 909996 4433775 LACR_0967 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_808935.1 909367 D 272622 CDS YP_808936.1 116511720 4433776 910067..910873 1 NC_008527.1 HAD superfamily hydrolase 910873 4433776 LACR_0968 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_808936.1 910067 D 272622 CDS YP_808937.1 116511721 4433777 910972..911562 1 NC_008527.1 peptidyl-prolyl cis-trans isomerase 911562 4433777 LACR_0969 Lactococcus lactis subsp. cremoris SK11 peptidyl-prolyl cis-trans isomerase YP_808937.1 910972 D 272622 CDS YP_808938.1 116511722 4433778 911564..911995 1 NC_008527.1 RNA-binding protein 911995 4433778 LACR_0970 Lactococcus lactis subsp. cremoris SK11 RNA-binding protein YP_808938.1 911564 D 272622 CDS YP_808939.1 116511723 4433779 911992..912597 1 NC_008527.1 hypothetical protein 912597 4433779 LACR_0971 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808939.1 911992 D 272622 CDS YP_808940.1 116511724 4433780 912809..914053 1 NC_008527.1 cell division membrane protein 914053 4433780 LACR_0972 Lactococcus lactis subsp. cremoris SK11 cell division membrane protein YP_808940.1 912809 D 272622 CDS YP_808941.1 116511725 4433782 915385..916146 1 NC_008527.1 acetoin reductase 916146 4433782 LACR_0974 Lactococcus lactis subsp. cremoris SK11 acetoin reductase YP_808941.1 915385 D 272622 CDS YP_808942.1 116511726 4433783 916419..916580 1 NC_008527.1 hypothetical protein 916580 4433783 LACR_0975 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808942.1 916419 D 272622 CDS YP_808943.1 116511727 4433784 916691..918241 1 NC_008527.1 ABC transporter ATPase 918241 4433784 LACR_0976 Lactococcus lactis subsp. cremoris SK11 ABC transporter ATPase YP_808943.1 916691 D 272622 CDS YP_808944.1 116511728 4432516 920293..921450 1 NC_008527.1 malate transporter 921450 4432516 LACR_0978 Lactococcus lactis subsp. cremoris SK11 malate transporter YP_808944.1 920293 D 272622 CDS YP_808945.1 116511729 4432517 921756..922655 1 NC_008527.1 DMT family permease 922655 4432517 LACR_0979 Lactococcus lactis subsp. cremoris SK11 DMT family permease YP_808945.1 921756 D 272622 CDS YP_808946.1 116511730 4432519 923524..925104 1 NC_008527.1 ABC transporter, permease protein 925104 4432519 LACR_0981 Lactococcus lactis subsp. cremoris SK11 ABC transporter, permease protein YP_808946.1 923524 D 272622 CDS YP_808947.1 116511731 4432520 925376..926125 1 NC_008527.1 ring-cleavage extradiol dioxygenase 926125 4432520 LACR_0982 Lactococcus lactis subsp. cremoris SK11 ring-cleavage extradiol dioxygenase YP_808947.1 925376 D 272622 CDS YP_808948.1 116511732 4432521 926191..926838 1 NC_008527.1 P-Ser-HPr phosphatase 926838 4432521 LACR_0983 Lactococcus lactis subsp. cremoris SK11 P-Ser-HPr phosphatase YP_808948.1 926191 D 272622 CDS YP_808949.1 116511733 4432522 926992..928947 1 NC_008527.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 928947 gyrB 4432522 gyrB Lactococcus lactis subsp. cremoris SK11 DNA gyrase subunit B YP_808949.1 926992 D 272622 CDS YP_808950.1 116511734 4432523 929046..929231 1 NC_008527.1 hypothetical protein 929231 4432523 LACR_0985 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808950.1 929046 D 272622 CDS YP_808951.1 116511735 4432524 929537..930712 1 NC_008527.1 transposase 930712 4432524 LACR_0986 Lactococcus lactis subsp. cremoris SK11 transposase YP_808951.1 929537 D 272622 CDS YP_808952.1 116511736 4432526 931681..932013 1 NC_008527.1 hypothetical protein 932013 4432526 LACR_0988 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808952.1 931681 D 272622 CDS YP_808953.1 116511737 4432528 complement(932404..933294) 1 NC_008527.1 transposase 933294 4432528 LACR_0990 Lactococcus lactis subsp. cremoris SK11 transposase YP_808953.1 932404 R 272622 CDS YP_808954.1 116511738 4432529 933458..934366 1 NC_008527.1 exopolysaccharide biosynthesis protein 934366 4432529 LACR_0991 Lactococcus lactis subsp. cremoris SK11 exopolysaccharide biosynthesis protein YP_808954.1 933458 D 272622 CDS YP_808955.1 116511739 4432530 934769..935029 1 NC_008527.1 transposase 935029 4432530 LACR_0992 Lactococcus lactis subsp. cremoris SK11 transposase YP_808955.1 934769 D 272622 CDS YP_808956.1 116511740 4432531 935041..935880 1 NC_008527.1 transposase 935880 4432531 LACR_0993 Lactococcus lactis subsp. cremoris SK11 transposase YP_808956.1 935041 D 272622 CDS YP_808957.1 116511741 4432532 935965..938244 1 NC_008527.1 lipopolysaccharide biosynthesis glycosyltransferase 938244 4432532 LACR_0994 Lactococcus lactis subsp. cremoris SK11 lipopolysaccharide biosynthesis glycosyltransferase YP_808957.1 935965 D 272622 CDS YP_808958.1 116511742 4432533 938231..939076 1 NC_008527.1 lipopolysaccharide biosynthesis glycosyltransferase 939076 4432533 LACR_0995 Lactococcus lactis subsp. cremoris SK11 lipopolysaccharide biosynthesis glycosyltransferase YP_808958.1 938231 D 272622 CDS YP_808959.1 116511743 4432764 939177..940067 1 NC_008527.1 transposase 940067 4432764 LACR_0996 Lactococcus lactis subsp. cremoris SK11 transposase YP_808959.1 939177 D 272622 CDS YP_808960.1 116511744 4432766 940306..941421 1 NC_008527.1 teichoic acid biosynthesis protein B 941421 4432766 LACR_0998 Lactococcus lactis subsp. cremoris SK11 teichoic acid biosynthesis protein B YP_808960.1 940306 D 272622 CDS YP_808961.1 116511745 4432767 941432..942091 1 NC_008527.1 transcriptional regulator 942091 4432767 LACR_0999 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_808961.1 941432 D 272622 CDS YP_808962.1 116511746 4432769 942538..943773 1 NC_008527.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 943773 4432769 LACR_1001 Lactococcus lactis subsp. cremoris SK11 phosphopentomutase YP_808962.1 942538 D 272622 CDS YP_808963.1 116511747 4432770 943831..944100 1 NC_008527.1 hypothetical protein 944100 4432770 LACR_1002 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808963.1 943831 D 272622 CDS YP_808964.1 116511748 4432771 944171..944875 1 NC_008527.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 944875 deoD 4432771 deoD Lactococcus lactis subsp. cremoris SK11 purine nucleoside phosphorylase YP_808964.1 944171 D 272622 CDS YP_808965.1 116511749 4432773 946133..946579 1 NC_008527.1 hypothetical protein 946579 4432773 LACR_1005 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808965.1 946133 D 272622 CDS YP_808966.1 116511750 4432774 946663..946989 1 NC_008527.1 hypothetical protein 946989 4432774 LACR_1006 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808966.1 946663 D 272622 CDS YP_808967.1 116511751 4432775 947150..948817 1 NC_008527.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 948817 4432775 LACR_1007 Lactococcus lactis subsp. cremoris SK11 formate--tetrahydrofolate ligase YP_808967.1 947150 D 272622 CDS YP_808968.1 116511752 4432776 948926..949519 1 NC_008527.1 cell wall-associated hydrolase 949519 4432776 LACR_1008 Lactococcus lactis subsp. cremoris SK11 cell wall-associated hydrolase YP_808968.1 948926 D 272622 CDS YP_808969.1 116511753 4432777 949662..950510 1 NC_008527.1 amino acid ABC transporter periplasmic protein 950510 4432777 LACR_1009 Lactococcus lactis subsp. cremoris SK11 amino acid ABC transporter periplasmic protein YP_808969.1 949662 D 272622 CDS YP_808970.1 116511754 4432778 950779..951666 1 NC_008527.1 ABC-type amino acid transport system, permease component 951666 4432778 LACR_1010 Lactococcus lactis subsp. cremoris SK11 ABC-type amino acid transport system, permease component YP_808970.1 950779 D 272622 CDS YP_808971.1 116511755 4432779 951678..952430 1 NC_008527.1 ABC-type polar amino acid transport system, ATPase component 952430 4432779 LACR_1011 Lactococcus lactis subsp. cremoris SK11 ABC-type polar amino acid transport system, ATPase component YP_808971.1 951678 D 272622 CDS YP_808972.1 116511756 4432780 952432..952659 1 NC_008527.1 hypothetical protein 952659 4432780 LACR_1012 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808972.1 952432 D 272622 CDS YP_808973.1 116511757 4434015 952857..953783 1 NC_008527.1 thioredoxin reductase 953783 4434015 LACR_1013 Lactococcus lactis subsp. cremoris SK11 thioredoxin reductase YP_808973.1 952857 D 272622 CDS YP_808974.1 116511758 4434016 953924..954172 1 NC_008527.1 preprotein translocase subunit SecG 954172 secG 4434016 secG Lactococcus lactis subsp. cremoris SK11 preprotein translocase subunit SecG YP_808974.1 953924 D 272622 CDS YP_808975.1 116511759 4434017 954435..956867 1 NC_008527.1 exoribonuclease R 956867 4434017 LACR_1015 Lactococcus lactis subsp. cremoris SK11 exoribonuclease R YP_808975.1 954435 D 272622 CDS YP_808976.1 116511760 4434018 956871..957473 1 NC_008527.1 amidase 957473 4434018 LACR_1016 Lactococcus lactis subsp. cremoris SK11 amidase YP_808976.1 956871 D 272622 CDS YP_808977.1 116511761 4434019 957551..958609 1 NC_008527.1 metal-dependent hydrolase 958609 4434019 LACR_1017 Lactococcus lactis subsp. cremoris SK11 metal-dependent hydrolase YP_808977.1 957551 D 272622 CDS YP_808978.1 116511762 4434020 complement(958702..959574) 1 NC_008527.1 1,4-dihydroxy-2-naphthoate octaprenyltransferase 959574 4434020 LACR_1018 Lactococcus lactis subsp. cremoris SK11 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_808978.1 958702 R 272622 CDS YP_808979.1 116511763 4434021 959728..959991 1 NC_008527.1 ACT domain-containing protein; hypothetical protein 959991 4434021 LACR_1019 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808979.1 959728 D 272622 CDS YP_808980.1 116511764 4434022 960108..961445 1 NC_008527.1 hypothetical protein 961445 4434022 LACR_1020 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808980.1 960108 D 272622 CDS YP_808981.1 116511765 4434023 961541..962020 1 NC_008527.1 hypothetical protein 962020 4434023 LACR_1021 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808981.1 961541 D 272622 CDS YP_808982.1 116511766 4434024 962091..962786 1 NC_008527.1 phosphoglycerate mutase 962786 4434024 LACR_1022 Lactococcus lactis subsp. cremoris SK11 phosphoglycerate mutase YP_808982.1 962091 D 272622 CDS YP_808983.1 116511767 4434025 962783..963529 1 NC_008527.1 D-alanyl-D-alanine carboxypeptidase 963529 4434025 LACR_1023 Lactococcus lactis subsp. cremoris SK11 D-alanyl-D-alanine carboxypeptidase YP_808983.1 962783 D 272622 CDS YP_808984.1 116511768 4434026 963544..963948 1 NC_008527.1 hypothetical protein 963948 4434026 LACR_1024 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808984.1 963544 D 272622 CDS YP_808985.1 116511769 4434027 964096..965139 1 NC_008527.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 965139 hrcA 4434027 hrcA Lactococcus lactis subsp. cremoris SK11 heat-inducible transcription repressor YP_808985.1 964096 D 272622 CDS YP_808986.1 116511770 4434028 965136..965708 1 NC_008527.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 965708 4434028 LACR_1026 Lactococcus lactis subsp. cremoris SK11 heat shock protein GrpE YP_808986.1 965136 D 272622 CDS YP_808987.1 116511771 4434029 965780..967603 1 NC_008527.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 967603 dnaK 4434029 dnaK Lactococcus lactis subsp. cremoris SK11 molecular chaperone DnaK YP_808987.1 965780 D 272622 CDS YP_808988.1 116511772 4434030 967766..969610 1 NC_008527.1 hypothetical protein 969610 4434030 LACR_1028 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808988.1 967766 D 272622 CDS YP_808989.1 116511773 4434031 969780..971543 1 NC_008527.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 971543 4434031 LACR_1029 Lactococcus lactis subsp. cremoris SK11 myosin-cross-reactive antigen YP_808989.1 969780 D 272622 CDS YP_808990.1 116511774 4434032 971610..972749 1 NC_008527.1 metal-dependent amidase/aminoacylase/carboxypeptidase 972749 4434032 LACR_1030 Lactococcus lactis subsp. cremoris SK11 metal-dependent amidase/aminoacylase/carboxypeptidase YP_808990.1 971610 D 272622 CDS YP_808991.1 116511775 4434069 972871..973572 1 NC_008527.1 lactose transport regulator 973572 4434069 LACR_1031 Lactococcus lactis subsp. cremoris SK11 lactose transport regulator YP_808991.1 972871 D 272622 CDS YP_808992.1 116511776 4434070 973655..974572 1 NC_008527.1 tagatose-6-phosphate kinase 974572 4434070 LACR_1032 Lactococcus lactis subsp. cremoris SK11 tagatose-6-phosphate kinase YP_808992.1 973655 D 272622 CDS YP_808993.1 116511777 4434071 974572..976476 1 NC_008527.1 fusion of IIA, IIB and IIC component of mannitol/fructose-specific phosphotransferase system mannitol/fructose-specific 976476 4434071 LACR_1033 Lactococcus lactis subsp. cremoris SK11 fusion of IIA, IIB and IIC component of mannitol/fructose-specific phosphotransferase system mannitol/fructose-specific YP_808993.1 974572 D 272622 CDS YP_808994.1 116511778 4434072 976561..977118 1 NC_008527.1 transposase 977118 4434072 LACR_1034 Lactococcus lactis subsp. cremoris SK11 transposase YP_808994.1 976561 D 272622 CDS YP_808995.1 116511779 4434073 977115..977936 1 NC_008527.1 transposase 977936 4434073 LACR_1035 Lactococcus lactis subsp. cremoris SK11 transposase YP_808995.1 977115 D 272622 CDS YP_808996.1 116511780 4434074 complement(977992..978831) 1 NC_008527.1 transposase 978831 4434074 LACR_1036 Lactococcus lactis subsp. cremoris SK11 transposase YP_808996.1 977992 R 272622 CDS YP_808997.1 116511781 4434075 complement(978849..979139) 1 NC_008527.1 transposase 979139 4434075 LACR_1037 Lactococcus lactis subsp. cremoris SK11 transposase YP_808997.1 978849 R 272622 CDS YP_808998.1 116511782 4434076 979417..980742 1 NC_008527.1 hypothetical protein 980742 4434076 LACR_1038 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808998.1 979417 D 272622 CDS YP_808999.1 116511783 4434077 981206..981607 1 NC_008527.1 hypothetical protein 981607 4434077 LACR_1039 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_808999.1 981206 D 272622 CDS YP_809000.1 116511784 4434078 981739..982110 1 NC_008527.1 hypothetical protein 982110 4434078 LACR_1040 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809000.1 981739 D 272622 CDS YP_809001.1 116511785 4434080 983246..985108 1 NC_008527.1 cation transport ATPase 985108 4434080 LACR_1042 Lactococcus lactis subsp. cremoris SK11 cation transport ATPase YP_809001.1 983246 D 272622 CDS YP_809002.1 116511786 4434081 985178..985405 1 NC_008527.1 hypothetical protein 985405 4434081 LACR_1043 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809002.1 985178 D 272622 CDS YP_809003.1 116511787 4434082 985420..985959 1 NC_008527.1 DNA-binding ferritin-like protein (oxidative damage protectant) 985959 4434082 LACR_1044 Lactococcus lactis subsp. cremoris SK11 DNA-binding ferritin-like protein (oxidative damage protectant) YP_809003.1 985420 D 272622 CDS YP_809004.1 116511788 4434083 985949..986638 1 NC_008527.1 Crp-like transcriptional regulator 986638 4434083 LACR_1045 Lactococcus lactis subsp. cremoris SK11 Crp-like transcriptional regulator YP_809004.1 985949 D 272622 CDS YP_809005.1 116511789 4434084 986830..988275 1 NC_008527.1 cardiolipin synthetase 2 988275 4434084 LACR_1046 Lactococcus lactis subsp. cremoris SK11 cardiolipin synthetase 2 YP_809005.1 986830 D 272622 CDS YP_809006.1 116511790 4434085 988340..989227 1 NC_008527.1 hypothetical protein 989227 4434085 LACR_1047 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809006.1 988340 D 272622 CDS YP_809007.1 116511791 4432481 989224..990207 1 NC_008527.1 hypothetical protein 990207 4432481 LACR_1048 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809007.1 989224 D 272622 CDS YP_809008.1 116511792 4432482 990303..991220 1 NC_008527.1 hypothetical protein 991220 4432482 LACR_1049 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809008.1 990303 D 272622 CDS YP_809009.1 116511793 4432483 complement(991253..991810) 1 NC_008527.1 transcriptional regulator 991810 4432483 LACR_1050 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809009.1 991253 R 272622 CDS YP_809010.1 116511794 4432484 992099..993007 1 NC_008527.1 ABC-type multidrug transport system, ATPase component 993007 4432484 LACR_1051 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase component YP_809010.1 992099 D 272622 CDS YP_809011.1 116511795 4432485 993107..994609 1 NC_008527.1 putative exporter of polyketide antibiotics 994609 4432485 LACR_1052 Lactococcus lactis subsp. cremoris SK11 putative exporter of polyketide antibiotics YP_809011.1 993107 D 272622 CDS YP_809012.1 116511796 4432486 complement(994742..995917) 1 NC_008527.1 transposase 995917 4432486 LACR_1053 Lactococcus lactis subsp. cremoris SK11 transposase YP_809012.1 994742 R 272622 CDS YP_809013.1 116511797 4432487 996085..996888 1 NC_008527.1 formate/nitrate transporter 996888 4432487 LACR_1054 Lactococcus lactis subsp. cremoris SK11 formate/nitrate transporter YP_809013.1 996085 D 272622 CDS YP_809014.1 116511798 4432488 complement(996903..997433) 1 NC_008527.1 hypothetical protein 997433 4432488 LACR_1055 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809014.1 996903 R 272622 CDS YP_809015.1 116511799 4432489 complement(997597..998484) 1 NC_008527.1 phosphohydrolase 998484 4432489 LACR_1056 Lactococcus lactis subsp. cremoris SK11 phosphohydrolase YP_809015.1 997597 R 272622 CDS YP_809016.1 116511800 4432490 998640..999737 1 NC_008527.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 999737 prfB 4432490 prfB Lactococcus lactis subsp. cremoris SK11 peptide chain release factor 2 YP_809016.1 998640 D 272622 CDS YP_809017.1 116511801 4432491 1000067..1000759 1 NC_008527.1 cell division ATP-binding protein FtsE 1000759 4432491 LACR_1058 Lactococcus lactis subsp. cremoris SK11 cell division ATP-binding protein FtsE YP_809017.1 1000067 D 272622 CDS YP_809018.1 116511802 4432492 1000752..1001687 1 NC_008527.1 cell division protein FtsX 1001687 4432492 LACR_1059 Lactococcus lactis subsp. cremoris SK11 cell division protein FtsX YP_809018.1 1000752 D 272622 CDS YP_809019.1 116511803 4432493 complement(1001797..1002774) 1 NC_008527.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1002774 nrdF 4432493 nrdF Lactococcus lactis subsp. cremoris SK11 ribonucleotide-diphosphate reductase subunit beta YP_809019.1 1001797 R 272622 CDS YP_809020.1 116511804 4432494 complement(1003059..1005227) 1 NC_008527.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1005227 4432494 LACR_1061 Lactococcus lactis subsp. cremoris SK11 ribonucleotide-diphosphate reductase subunit alpha YP_809020.1 1003059 R 272622 CDS YP_809021.1 116511805 4432495 complement(1005364..1005786) 1 NC_008527.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 1005786 nrdI 4432495 nrdI Lactococcus lactis subsp. cremoris SK11 ribonucleotide reductase stimulatory protein YP_809021.1 1005364 R 272622 CDS YP_809022.1 116511806 4432496 complement(1005788..1006006) 1 NC_008527.1 ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit 1006006 4432496 LACR_1063 Lactococcus lactis subsp. cremoris SK11 ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit YP_809022.1 1005788 R 272622 CDS YP_809023.1 116511807 4432497 complement(1006180..1006821) 1 NC_008527.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 1006821 4432497 LACR_1064 Lactococcus lactis subsp. cremoris SK11 putative glycerol-3-phosphate acyltransferase PlsY YP_809023.1 1006180 R 272622 CDS YP_809024.1 116511808 4432498 1007100..1009034 1 NC_008527.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1009034 4432498 LACR_1065 Lactococcus lactis subsp. cremoris SK11 DNA topoisomerase IV subunit B YP_809024.1 1007100 D 272622 CDS YP_809025.1 116511809 4434286 1009291..1009494 1 NC_008527.1 amidase 1009494 4434286 LACR_1066 Lactococcus lactis subsp. cremoris SK11 amidase YP_809025.1 1009291 D 272622 CDS YP_809026.1 116511810 4434287 1009491..1009676 1 NC_008527.1 amidase 1009676 4434287 LACR_1067 Lactococcus lactis subsp. cremoris SK11 amidase YP_809026.1 1009491 D 272622 CDS YP_809027.1 116511811 4434288 1009669..1010502 1 NC_008527.1 DNA polymerase III, epsilon chain 1010502 4434288 LACR_1068 Lactococcus lactis subsp. cremoris SK11 DNA polymerase III, epsilon chain YP_809027.1 1009669 D 272622 CDS YP_809028.1 116511812 4434289 1010499..1010948 1 NC_008527.1 acetyltransferase 1010948 4434289 LACR_1069 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_809028.1 1010499 D 272622 CDS YP_809029.1 116511813 4434290 1011221..1013695 1 NC_008527.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1013695 4434290 LACR_1070 Lactococcus lactis subsp. cremoris SK11 DNA topoisomerase IV subunit A YP_809029.1 1011221 D 272622 CDS YP_809030.1 116511814 4434291 complement(1013721..1014626) 1 NC_008527.1 Mg2+ and Co2+ transporter 1014626 4434291 LACR_1071 Lactococcus lactis subsp. cremoris SK11 Mg2+ and Co2+ transporter YP_809030.1 1013721 R 272622 CDS YP_809031.1 116511815 4434293 1016205..1016852 1 NC_008527.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1016852 4434293 LACR_1073 Lactococcus lactis subsp. cremoris SK11 riboflavin synthase subunit alpha YP_809031.1 1016205 D 272622 CDS YP_809032.1 116511816 4434294 1016864..1018060 1 NC_008527.1 GTP cyclohydrolase II 1018060 4434294 LACR_1074 Lactococcus lactis subsp. cremoris SK11 GTP cyclohydrolase II YP_809032.1 1016864 D 272622 CDS YP_809033.1 116511817 4434295 1018075..1018551 1 NC_008527.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1018551 ribH 4434295 ribH Lactococcus lactis subsp. cremoris SK11 6,7-dimethyl-8-ribityllumazine synthase YP_809033.1 1018075 D 272622 CDS YP_809034.1 116511818 4434297 complement(1019891..1020088) 1 NC_008527.1 hypothetical protein 1020088 4434297 LACR_1077 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809034.1 1019891 R 272622 CDS YP_809035.1 116511819 4434298 complement(1020370..1020768) 1 NC_008527.1 transcriptional regulator 1020768 4434298 LACR_1078 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809035.1 1020370 R 272622 CDS YP_809036.1 116511820 4434299 1020835..1021188 1 NC_008527.1 hypothetical protein 1021188 4434299 LACR_1079 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809036.1 1020835 D 272622 CDS YP_809037.1 116511821 4434300 1021268..1022443 1 NC_008527.1 transposase 1022443 4434300 LACR_1080 Lactococcus lactis subsp. cremoris SK11 transposase YP_809037.1 1021268 D 272622 CDS YP_809038.1 116511822 4434301 1022825..1023277 1 NC_008527.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1023277 lspA 4434301 lspA Lactococcus lactis subsp. cremoris SK11 lipoprotein signal peptidase YP_809038.1 1022825 D 272622 CDS YP_809039.1 116511823 4434302 1023340..1024245 1 NC_008527.1 ribosomal large subunit pseudouridine synthase D 1024245 4434302 LACR_1082 Lactococcus lactis subsp. cremoris SK11 ribosomal large subunit pseudouridine synthase D YP_809039.1 1023340 D 272622 CDS YP_809040.1 116511824 4434033 1024403..1024846 1 NC_008527.1 hypothetical protein 1024846 4434033 LACR_1083 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809040.1 1024403 D 272622 CDS YP_809041.1 116511825 4434034 1025100..1025657 1 NC_008527.1 transposase 1025657 4434034 LACR_1084 Lactococcus lactis subsp. cremoris SK11 transposase YP_809041.1 1025100 D 272622 CDS YP_809042.1 116511826 4434035 1025654..1026475 1 NC_008527.1 transposase 1026475 4434035 LACR_1085 Lactococcus lactis subsp. cremoris SK11 transposase YP_809042.1 1025654 D 272622 CDS YP_809043.1 116511827 4434036 1026547..1026837 1 NC_008527.1 transposase 1026837 4434036 LACR_1086 Lactococcus lactis subsp. cremoris SK11 transposase YP_809043.1 1026547 D 272622 CDS YP_809044.1 116511828 4434037 1026855..1027694 1 NC_008527.1 transposase 1027694 4434037 LACR_1087 Lactococcus lactis subsp. cremoris SK11 transposase YP_809044.1 1026855 D 272622 CDS YP_809045.1 116511829 4434038 1027763..1029352 1 NC_008527.1 hypothetical protein 1029352 4434038 LACR_1088 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809045.1 1027763 D 272622 CDS YP_809046.1 116511830 4434039 1029355..1030311 1 NC_008527.1 glycosyltransferase 1030311 4434039 LACR_1089 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_809046.1 1029355 D 272622 CDS YP_809047.1 116511831 4434040 1030439..1031125 1 NC_008527.1 DNA-binding response regulator 1031125 4434040 LACR_1090 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_809047.1 1030439 D 272622 CDS YP_809048.1 116511832 4434041 1031146..1031661 1 NC_008527.1 hypothetical protein 1031661 4434041 LACR_1091 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809048.1 1031146 D 272622 CDS YP_809049.1 116511833 4434042 1031665..1032990 1 NC_008527.1 Signal transduction histidine kinase 1032990 4434042 LACR_1092 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_809049.1 1031665 D 272622 CDS YP_809050.1 116511834 4434043 1033000..1033656 1 NC_008527.1 membrane-associated phospholipid phosphatase 1033656 4434043 LACR_1093 Lactococcus lactis subsp. cremoris SK11 membrane-associated phospholipid phosphatase YP_809050.1 1033000 D 272622 CDS YP_809051.1 116511835 4434044 1033838..1035655 1 NC_008527.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1035655 4434044 LACR_1094 Lactococcus lactis subsp. cremoris SK11 glucosamine--fructose-6-phosphate aminotransferase YP_809051.1 1033838 D 272622 CDS YP_809052.1 116511836 4434045 1035804..1036457 1 NC_008527.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1036457 radC 4434045 radC Lactococcus lactis subsp. cremoris SK11 DNA repair protein RadC YP_809052.1 1035804 D 272622 CDS YP_809053.1 116511837 4434046 complement(1036757..1037881) 1 NC_008527.1 integrase 1037881 4434046 LACR_1096 Lactococcus lactis subsp. cremoris SK11 integrase YP_809053.1 1036757 R 272622 CDS YP_809054.1 116511838 4434047 complement(1038005..1038838) 1 NC_008527.1 hypothetical protein 1038838 4434047 LACR_1097 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809054.1 1038005 R 272622 CDS YP_809055.1 116511839 4434048 complement(1038857..1039423) 1 NC_008527.1 hypothetical protein 1039423 4434048 LACR_1098 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809055.1 1038857 R 272622 CDS YP_809056.1 116511840 4434049 complement(1039452..1039799) 1 NC_008527.1 XRE family transcriptional regulator 1039799 4434049 LACR_1099 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_809056.1 1039452 R 272622 CDS YP_809057.1 116511841 4434050 1040090..1040320 1 NC_008527.1 hypothetical protein 1040320 4434050 LACR_1100 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809057.1 1040090 D 272622 CDS YP_809058.1 116511842 4434321 1040335..1041057 1 NC_008527.1 Phage anti-repressor protein 1041057 4434321 LACR_1101 Lactococcus lactis subsp. cremoris SK11 Phage anti-repressor protein YP_809058.1 1040335 D 272622 CDS YP_809059.1 116511843 4434322 1041070..1041405 1 NC_008527.1 hypothetical protein 1041405 4434322 LACR_1102 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809059.1 1041070 D 272622 CDS YP_809060.1 116511844 4434323 1041402..1041530 1 NC_008527.1 hypothetical protein 1041530 4434323 LACR_1103 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809060.1 1041402 D 272622 CDS YP_809061.1 116511845 4434324 1041543..1041737 1 NC_008527.1 hypothetical protein 1041737 4434324 LACR_1104 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809061.1 1041543 D 272622 CDS YP_809062.1 116511846 4434325 complement(1041734..1042009) 1 NC_008527.1 hypothetical protein 1042009 4434325 LACR_1105 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809062.1 1041734 R 272622 CDS YP_809063.1 116511847 4434326 1042115..1042363 1 NC_008527.1 hypothetical protein 1042363 4434326 LACR_1106 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809063.1 1042115 D 272622 CDS YP_809064.1 116511848 4434327 1042466..1042855 1 NC_008527.1 hypothetical protein 1042855 4434327 LACR_1107 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809064.1 1042466 D 272622 CDS YP_809065.1 116511849 4434328 1042866..1043474 1 NC_008527.1 hypothetical protein 1043474 4434328 LACR_1108 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809065.1 1042866 D 272622 CDS YP_809066.1 116511850 4434329 1043474..1043824 1 NC_008527.1 RecG-like helicase 1043824 4434329 LACR_1109 Lactococcus lactis subsp. cremoris SK11 RecG-like helicase YP_809066.1 1043474 D 272622 CDS YP_809067.1 116511851 4434330 1043958..1044767 1 NC_008527.1 hypothetical protein 1044767 4434330 LACR_1110 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809067.1 1043958 D 272622 CDS YP_809068.1 116511852 4434331 1044748..1044969 1 NC_008527.1 hypothetical protein 1044969 4434331 LACR_1111 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809068.1 1044748 D 272622 CDS YP_809069.1 116511853 4434332 1044959..1045348 1 NC_008527.1 Holliday junction resolvase 1045348 4434332 LACR_1112 Lactococcus lactis subsp. cremoris SK11 Holliday junction resolvase YP_809069.1 1044959 D 272622 CDS YP_809070.1 116511854 4434333 1045352..1045591 1 NC_008527.1 hypothetical protein 1045591 4434333 LACR_1113 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809070.1 1045352 D 272622 CDS YP_809071.1 116511855 4434334 1045702..1045986 1 NC_008527.1 hypothetical protein 1045986 4434334 LACR_1114 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809071.1 1045702 D 272622 CDS YP_809072.1 116511856 4434335 1046008..1046187 1 NC_008527.1 hypothetical protein 1046187 4434335 LACR_1115 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809072.1 1046008 D 272622 CDS YP_809073.1 116511857 4434336 1046177..1046749 1 NC_008527.1 hypothetical protein 1046749 4434336 LACR_1116 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809073.1 1046177 D 272622 CDS YP_809074.1 116511858 4434337 1046764..1047096 1 NC_008527.1 hypothetical protein 1047096 4434337 LACR_1117 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809074.1 1046764 D 272622 CDS YP_809075.1 116511859 4434477 1047120..1047479 1 NC_008527.1 hypothetical protein 1047479 4434477 LACR_1118 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809075.1 1047120 D 272622 CDS YP_809076.1 116511860 4434478 1047472..1048137 1 NC_008527.1 hypothetical protein 1048137 4434478 LACR_1119 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809076.1 1047472 D 272622 CDS YP_809077.1 116511861 4434479 1048134..1048298 1 NC_008527.1 hypothetical protein 1048298 4434479 LACR_1120 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809077.1 1048134 D 272622 CDS YP_809078.1 116511862 4434480 1048295..1048423 1 NC_008527.1 hypothetical protein 1048423 4434480 LACR_1121 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809078.1 1048295 D 272622 CDS YP_809079.1 116511863 4434481 1048439..1048894 1 NC_008527.1 deoxyuridine 5'-triphosphate nucleotidohydrolase 1048894 4434481 LACR_1122 Lactococcus lactis subsp. cremoris SK11 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_809079.1 1048439 D 272622 CDS YP_809080.1 116511864 4434482 1048913..1049098 1 NC_008527.1 hypothetical protein 1049098 4434482 LACR_1123 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809080.1 1048913 D 272622 CDS YP_809081.1 116511865 4434483 1049095..1049238 1 NC_008527.1 hypothetical protein 1049238 4434483 LACR_1124 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809081.1 1049095 D 272622 CDS YP_809082.1 116511866 4434484 1049246..1049431 1 NC_008527.1 hypothetical protein 1049431 4434484 LACR_1125 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809082.1 1049246 D 272622 CDS YP_809083.1 116511867 4434485 1049428..1049646 1 NC_008527.1 hypothetical protein 1049646 4434485 LACR_1126 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809083.1 1049428 D 272622 CDS YP_809084.1 116511868 4434486 1049639..1049821 1 NC_008527.1 hypothetical protein 1049821 4434486 LACR_1127 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809084.1 1049639 D 272622 CDS YP_809085.1 116511869 4434487 1049818..1049955 1 NC_008527.1 hypothetical protein 1049955 4434487 LACR_1128 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809085.1 1049818 D 272622 CDS YP_809086.1 116511870 4434488 1050078..1050221 1 NC_008527.1 hypothetical protein 1050221 4434488 LACR_1129 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809086.1 1050078 D 272622 CDS YP_809087.1 116511871 4434489 1050298..1050720 1 NC_008527.1 hypothetical protein 1050720 4434489 LACR_1130 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809087.1 1050298 D 272622 CDS YP_809088.1 116511872 4434491 1051168..1051635 1 NC_008527.1 Phage terminase, small subunit 1051635 4434491 LACR_1132 Lactococcus lactis subsp. cremoris SK11 Phage terminase, small subunit YP_809088.1 1051168 D 272622 CDS YP_809089.1 116511873 4434492 1051628..1053016 1 NC_008527.1 Phage terminase, large subunit 1053016 4434492 LACR_1133 Lactococcus lactis subsp. cremoris SK11 Phage terminase, large subunit YP_809089.1 1051628 D 272622 CDS YP_809090.1 116511874 4434493 1053017..1054378 1 NC_008527.1 Phage portal protein, SPP1 Gp6-like 1054378 4434493 LACR_1134 Lactococcus lactis subsp. cremoris SK11 Phage portal protein, SPP1 Gp6-like YP_809090.1 1053017 D 272622 CDS YP_809091.1 116511875 4432680 1054382..1055425 1 NC_008527.1 Phage Mu protein F like protein 1055425 4432680 LACR_1135 Lactococcus lactis subsp. cremoris SK11 Phage Mu protein F like protein YP_809091.1 1054382 D 272622 CDS YP_809092.1 116511876 4432681 1055540..1056202 1 NC_008527.1 hypothetical protein 1056202 4432681 LACR_1136 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809092.1 1055540 D 272622 CDS YP_809093.1 116511877 4432682 1056204..1057022 1 NC_008527.1 hypothetical protein 1057022 4432682 LACR_1137 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809093.1 1056204 D 272622 CDS YP_809094.1 116511878 4432683 1057022..1057222 1 NC_008527.1 hypothetical protein 1057222 4432683 LACR_1138 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809094.1 1057022 D 272622 CDS YP_809095.1 116511879 4432684 1057206..1057538 1 NC_008527.1 hypothetical protein 1057538 4432684 LACR_1139 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809095.1 1057206 D 272622 CDS YP_809096.1 116511880 4432685 1057535..1057846 1 NC_008527.1 hypothetical protein 1057846 4432685 LACR_1140 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809096.1 1057535 D 272622 CDS YP_809097.1 116511881 4432686 1057843..1058169 1 NC_008527.1 hypothetical protein 1058169 4432686 LACR_1141 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809097.1 1057843 D 272622 CDS YP_809098.1 116511882 4432687 1058166..1058561 1 NC_008527.1 hypothetical protein 1058561 4432687 LACR_1142 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809098.1 1058166 D 272622 CDS YP_809099.1 116511883 4432688 1058572..1059081 1 NC_008527.1 hypothetical protein 1059081 4432688 LACR_1143 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809099.1 1058572 D 272622 CDS YP_809100.1 116511884 4432689 1059197..1059547 1 NC_008527.1 hypothetical protein 1059547 4432689 LACR_1144 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809100.1 1059197 D 272622 CDS YP_809101.1 116511885 4432690 1059631..1059900 1 NC_008527.1 hypothetical protein 1059900 4432690 LACR_1145 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809101.1 1059631 D 272622 CDS YP_809102.1 116511886 4432691 1059916..1062540 1 NC_008527.1 minor tail protein gp26-like protein 1062540 4432691 LACR_1146 Lactococcus lactis subsp. cremoris SK11 minor tail protein gp26-like protein YP_809102.1 1059916 D 272622 CDS YP_809103.1 116511887 4432692 1062550..1063311 1 NC_008527.1 hypothetical protein 1063311 4432692 LACR_1147 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809103.1 1062550 D 272622 CDS YP_809104.1 116511888 4432693 1063311..1066250 1 NC_008527.1 phage-associated peptidase 1066250 4432693 LACR_1148 Lactococcus lactis subsp. cremoris SK11 phage-associated peptidase YP_809104.1 1063311 D 272622 CDS YP_809105.1 116511889 4432694 1066268..1068712 1 NC_008527.1 hypothetical protein 1068712 4432694 LACR_1149 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809105.1 1066268 D 272622 CDS YP_809106.1 116511890 4432695 1068834..1068995 1 NC_008527.1 hypothetical protein 1068995 4432695 LACR_1150 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809106.1 1068834 D 272622 CDS YP_809107.1 116511891 4432696 1069110..1069412 1 NC_008527.1 hypothetical protein 1069412 4432696 LACR_1151 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809107.1 1069110 D 272622 CDS YP_809108.1 116511892 4433909 1069402..1069626 1 NC_008527.1 hypothetical protein 1069626 4433909 LACR_1152 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809108.1 1069402 D 272622 CDS YP_809109.1 116511893 4433910 1069623..1070912 1 NC_008527.1 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) 1070912 4433910 LACR_1153 Lactococcus lactis subsp. cremoris SK11 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) YP_809109.1 1069623 D 272622 CDS YP_809110.1 116511894 4433911 1071111..1071410 1 NC_008527.1 hypothetical protein 1071410 4433911 LACR_1154 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809110.1 1071111 D 272622 CDS YP_809111.1 116511895 4433912 1071424..1072335 1 NC_008527.1 phage-associated protein 1072335 4433912 LACR_1155 Lactococcus lactis subsp. cremoris SK11 phage-associated protein YP_809111.1 1071424 D 272622 CDS YP_809112.1 116511896 4433913 complement(1072691..1073341) 1 NC_008527.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1073341 4433913 LACR_1156 Lactococcus lactis subsp. cremoris SK11 redox-sensing transcriptional repressor Rex YP_809112.1 1072691 R 272622 CDS YP_809113.1 116511897 4433914 1073564..1073956 1 NC_008527.1 arsenate reductase 1073956 4433914 LACR_1157 Lactococcus lactis subsp. cremoris SK11 arsenate reductase YP_809113.1 1073564 D 272622 CDS YP_809114.1 116511898 4433915 1074129..1076036 1 NC_008527.1 ABC transporter ATPase 1076036 4433915 LACR_1158 Lactococcus lactis subsp. cremoris SK11 ABC transporter ATPase YP_809114.1 1074129 D 272622 CDS YP_809115.1 116511899 4433916 1076457..1077086 1 NC_008527.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1077086 pyrE 4433916 pyrE Lactococcus lactis subsp. cremoris SK11 orotate phosphoribosyltransferase YP_809115.1 1076457 D 272622 CDS YP_809116.1 116511900 4433917 1077239..1078510 1 NC_008527.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1078510 pyrC 4433917 pyrC Lactococcus lactis subsp. cremoris SK11 dihydroorotase YP_809116.1 1077239 D 272622 CDS YP_809117.1 116511901 4433918 1078917..1079834 1 NC_008527.1 TPR repeat-containing protein 1079834 4433918 LACR_1161 Lactococcus lactis subsp. cremoris SK11 TPR repeat-containing protein YP_809117.1 1078917 D 272622 CDS YP_809118.1 116511902 4433919 complement(1080025..1080864) 1 NC_008527.1 transposase 1080864 4433919 LACR_1162 Lactococcus lactis subsp. cremoris SK11 transposase YP_809118.1 1080025 R 272622 CDS YP_809119.1 116511903 4433920 complement(1081283..1082458) 1 NC_008527.1 transposase 1082458 4433920 LACR_1163 Lactococcus lactis subsp. cremoris SK11 transposase YP_809119.1 1081283 R 272622 CDS YP_809120.1 116511904 4433921 1082573..1083169 1 NC_008527.1 hypothetical protein 1083169 4433921 LACR_1164 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809120.1 1082573 D 272622 CDS YP_809121.1 116511905 4433922 1083166..1083345 1 NC_008527.1 hypothetical protein 1083345 4433922 LACR_1165 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809121.1 1083166 D 272622 CDS YP_809122.1 116511906 4433923 1083382..1083642 1 NC_008527.1 transposase 1083642 4433923 LACR_1166 Lactococcus lactis subsp. cremoris SK11 transposase YP_809122.1 1083382 D 272622 CDS YP_809123.1 116511907 4433924 1083639..1084493 1 NC_008527.1 transposase 1084493 4433924 LACR_1167 Lactococcus lactis subsp. cremoris SK11 transposase YP_809123.1 1083639 D 272622 CDS YP_809124.1 116511908 4433925 1084597..1084998 1 NC_008527.1 hypothetical protein 1084998 4433925 LACR_1168 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809124.1 1084597 D 272622 CDS YP_809125.1 116511909 4433926 complement(1085156..1085272) 1 NC_008527.1 hypothetical protein 1085272 4433926 LACR_1169 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809125.1 1085156 R 272622 CDS YP_809126.1 116511910 4432447 1085529..1087958 1 NC_008527.1 hypothetical protein 1087958 4432447 LACR_1170 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809126.1 1085529 D 272622 CDS YP_809127.1 116511911 4432448 1088223..1088891 1 NC_008527.1 DNA replication protein DnaD 1088891 4432448 LACR_1171 Lactococcus lactis subsp. cremoris SK11 DNA replication protein DnaD YP_809127.1 1088223 D 272622 CDS YP_809128.1 116511912 4432449 1088913..1089569 1 NC_008527.1 endonuclease III / DNA-(apurinic or apyrimidinic site) lyase 1089569 4432449 LACR_1172 Lactococcus lactis subsp. cremoris SK11 endonuclease III / DNA-(apurinic or apyrimidinic site) lyase YP_809128.1 1088913 D 272622 CDS YP_809129.1 116511913 4432450 1089562..1090251 1 NC_008527.1 SAM-dependent methyltransferase 1090251 4432450 LACR_1173 Lactococcus lactis subsp. cremoris SK11 SAM-dependent methyltransferase YP_809129.1 1089562 D 272622 CDS YP_809130.1 116511914 4432451 1090248..1091021 1 NC_008527.1 hypothetical protein 1091021 4432451 LACR_1174 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809130.1 1090248 D 272622 CDS YP_809131.1 116511915 4432452 complement(1091056..1091421) 1 NC_008527.1 hypothetical protein 1091421 4432452 LACR_1175 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809131.1 1091056 R 272622 CDS YP_809132.1 116511916 4432453 complement(1091560..1092375) 1 NC_008527.1 HAD superfamily hydrolase 1092375 4432453 LACR_1176 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_809132.1 1091560 R 272622 CDS YP_809133.1 116511917 4432454 complement(1092428..1093771) 1 NC_008527.1 HD superfamily phosphohydrolase 1093771 4432454 LACR_1177 Lactococcus lactis subsp. cremoris SK11 HD superfamily phosphohydrolase YP_809133.1 1092428 R 272622 CDS YP_809134.1 116511918 4432455 1093944..1094342 1 NC_008527.1 hypothetical protein 1094342 4432455 LACR_1178 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809134.1 1093944 D 272622 CDS YP_809135.1 116511919 4432456 1094335..1095510 1 NC_008527.1 hypothetical protein 1095510 4432456 LACR_1179 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809135.1 1094335 D 272622 CDS YP_809136.1 116511920 4432457 1095680..1095994 1 NC_008527.1 50S ribosomal protein L21 1095994 rplU 4432457 rplU Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L21 YP_809136.1 1095680 D 272622 CDS YP_809137.1 116511921 4432458 1095997..1096332 1 NC_008527.1 hypothetical protein 1096332 4432458 LACR_1181 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809137.1 1095997 D 272622 CDS YP_809138.1 116511922 4432459 1096334..1096618 1 NC_008527.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1096618 rpmA 4432459 rpmA Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L27 YP_809138.1 1096334 D 272622 CDS YP_809139.1 116511923 4432460 1096985..1098406 1 NC_008527.1 manganese transporter NRAMP 1098406 4432460 LACR_1183 Lactococcus lactis subsp. cremoris SK11 manganese transporter NRAMP YP_809139.1 1096985 D 272622 CDS YP_809140.1 116511924 4432461 1098489..1099448 1 NC_008527.1 phosphate starvation-inducible protein PhoH, ATPase 1099448 4432461 LACR_1184 Lactococcus lactis subsp. cremoris SK11 phosphate starvation-inducible protein PhoH, ATPase YP_809140.1 1098489 D 272622 CDS YP_809141.1 116511925 4432462 1099518..1100012 1 NC_008527.1 ADP-ribose pyrophosphatase 1100012 4432462 LACR_1185 Lactococcus lactis subsp. cremoris SK11 ADP-ribose pyrophosphatase YP_809141.1 1099518 D 272622 CDS YP_809142.1 116511926 4432463 1100103..1100591 1 NC_008527.1 putative metalloprotease 1100591 4432463 LACR_1186 Lactococcus lactis subsp. cremoris SK11 putative metalloprotease YP_809142.1 1100103 D 272622 CDS YP_809143.1 116511927 4432662 1100575..1101030 1 NC_008527.1 diacylglycerol kinase 1101030 4432662 LACR_1187 Lactococcus lactis subsp. cremoris SK11 diacylglycerol kinase YP_809143.1 1100575 D 272622 CDS YP_809144.1 116511928 4432663 1101047..1101625 1 NC_008527.1 hypothetical protein 1101625 4432663 LACR_1188 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809144.1 1101047 D 272622 CDS YP_809145.1 116511929 4432664 complement(1101683..1102333) 1 NC_008527.1 amidophosphoribosyltransferase 1102333 4432664 LACR_1189 Lactococcus lactis subsp. cremoris SK11 amidophosphoribosyltransferase YP_809145.1 1101683 R 272622 CDS YP_809146.1 116511930 4432666 1103684..1104319 1 NC_008527.1 hypothetical protein 1104319 4432666 LACR_1191 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809146.1 1103684 D 272622 CDS YP_809147.1 116511931 4432668 1104927..1105946 1 NC_008527.1 hypothetical protein 1105946 4432668 LACR_1193 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809147.1 1104927 D 272622 CDS YP_809148.1 116511932 4432669 1106055..1106822 1 NC_008527.1 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase 1106822 4432669 LACR_1194 Lactococcus lactis subsp. cremoris SK11 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase YP_809148.1 1106055 D 272622 CDS YP_809149.1 116511933 4432670 1107059..1107706 1 NC_008527.1 hypothetical protein 1107706 4432670 LACR_1195 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809149.1 1107059 D 272622 CDS YP_809150.1 116511934 4432671 1107706..1108659 1 NC_008527.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1108659 glyQ 4432671 glyQ Lactococcus lactis subsp. cremoris SK11 glycyl-tRNA synthetase subunit alpha YP_809150.1 1107706 D 272622 CDS YP_809151.1 116511935 4432672 1108659..1110680 1 NC_008527.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1110680 glyS 4432672 glyS Lactococcus lactis subsp. cremoris SK11 glycyl-tRNA synthetase subunit beta YP_809151.1 1108659 D 272622 CDS YP_809152.1 116511936 4432673 1110788..1111030 1 NC_008527.1 hypothetical protein 1111030 4432673 LACR_1198 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809152.1 1110788 D 272622 CDS YP_809153.1 116511937 4432674 1111434..1112645 1 NC_008527.1 chloride channel protein EriC 1112645 4432674 LACR_1199 Lactococcus lactis subsp. cremoris SK11 chloride channel protein EriC YP_809153.1 1111434 D 272622 CDS YP_809154.1 116511938 4432675 complement(1112660..1113253) 1 NC_008527.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1113253 nadD 4432675 nadD Lactococcus lactis subsp. cremoris SK11 nicotinic acid mononucleotide adenylyltransferase YP_809154.1 1112660 R 272622 CDS YP_809155.1 116511939 4432676 complement(1113405..1113590) 1 NC_008527.1 hypothetical protein 1113590 4432676 LACR_1201 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809155.1 1113405 R 272622 CDS YP_809156.1 116511940 4432677 1113836..1115308 1 NC_008527.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1115308 4432677 LACR_1202 Lactococcus lactis subsp. cremoris SK11 nicotinate phosphoribosyltransferase YP_809156.1 1113836 D 272622 CDS YP_809157.1 116511941 4432678 1115308..1115793 1 NC_008527.1 acetyltransferase 1115793 4432678 LACR_1203 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_809157.1 1115308 D 272622 CDS YP_809158.1 116511942 4432679 1115850..1116674 1 NC_008527.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1116674 nadE 4432679 nadE Lactococcus lactis subsp. cremoris SK11 NAD synthetase YP_809158.1 1115850 D 272622 CDS YP_809159.1 116511943 4433663 1116876..1117577 1 NC_008527.1 peptide ABC transporter ATPase 1117577 4433663 LACR_1205 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter ATPase YP_809159.1 1116876 D 272622 CDS YP_809160.1 116511944 4433664 1117581..1120187 1 NC_008527.1 peptide ABC transporter permease 1120187 4433664 LACR_1206 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter permease YP_809160.1 1117581 D 272622 CDS YP_809161.1 116511945 4433665 complement(1120261..1121049) 1 NC_008527.1 cobyric acid synthase 1121049 4433665 LACR_1207 Lactococcus lactis subsp. cremoris SK11 cobyric acid synthase YP_809161.1 1120261 R 272622 CDS YP_809162.1 116511946 4433666 complement(1121050..1122399) 1 NC_008527.1 UDP-N-acetylmuramyl tripeptide synthase 1122399 4433666 LACR_1208 Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylmuramyl tripeptide synthase YP_809162.1 1121050 R 272622 CDS YP_809163.1 116511947 4433667 1122498..1123163 1 NC_008527.1 Alpha-acetolactate decarboxylase 1123163 4433667 LACR_1209 Lactococcus lactis subsp. cremoris SK11 Alpha-acetolactate decarboxylase YP_809163.1 1122498 D 272622 CDS YP_809164.1 116511948 4433668 1123436..1125259 1 NC_008527.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1125259 4433668 LACR_1210 Lactococcus lactis subsp. cremoris SK11 GTP-binding protein LepA YP_809164.1 1123436 D 272622 CDS YP_809165.1 116511949 4433669 1125326..1125961 1 NC_008527.1 nucleoside-diphosphate-sugar epimerase 1125961 4433669 LACR_1211 Lactococcus lactis subsp. cremoris SK11 nucleoside-diphosphate-sugar epimerase YP_809165.1 1125326 D 272622 CDS YP_809166.1 116511950 4433671 1127056..1127316 1 NC_008527.1 transposase 1127316 4433671 LACR_1213 Lactococcus lactis subsp. cremoris SK11 transposase YP_809166.1 1127056 D 272622 CDS YP_809167.1 116511951 4433672 1127313..1128167 1 NC_008527.1 transposase 1128167 4433672 LACR_1214 Lactococcus lactis subsp. cremoris SK11 transposase YP_809167.1 1127313 D 272622 CDS YP_809168.1 116511952 4433673 1128225..1129613 1 NC_008527.1 Type I restriction-modification system methyltransferase subunit 1129613 4433673 LACR_1215 Lactococcus lactis subsp. cremoris SK11 Type I restriction-modification system methyltransferase subunit YP_809168.1 1128225 D 272622 CDS YP_809169.1 116511953 4433674 1129808..1132318 1 NC_008527.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1132318 4433674 LACR_1216 Lactococcus lactis subsp. cremoris SK11 DNA gyrase subunit A YP_809169.1 1129808 D 272622 CDS YP_809170.1 116511954 4433675 1132400..1133485 1 NC_008527.1 membrane-associated lipoprotein for thiamine biosynthesis 1133485 4433675 LACR_1217 Lactococcus lactis subsp. cremoris SK11 membrane-associated lipoprotein for thiamine biosynthesis YP_809170.1 1132400 D 272622 CDS YP_809171.1 116511955 4433676 1133608..1134360 1 NC_008527.1 sortase (surface protein transpeptidase) 1134360 4433676 LACR_1218 Lactococcus lactis subsp. cremoris SK11 sortase (surface protein transpeptidase) YP_809171.1 1133608 D 272622 CDS YP_809172.1 116511956 4433677 1134579..1137332 1 NC_008527.1 hypothetical protein 1137332 4433677 LACR_1219 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809172.1 1134579 D 272622 CDS YP_809173.1 116511957 4433678 1137319..1137948 1 NC_008527.1 hypothetical protein 1137948 4433678 LACR_1220 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809173.1 1137319 D 272622 CDS YP_809174.1 116511958 4433679 complement(1137893..1138669) 1 NC_008527.1 hypothetical protein 1138669 4433679 LACR_1221 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809174.1 1137893 R 272622 CDS YP_809175.1 116511959 4433628 1138820..1141096 1 NC_008527.1 ATP-dependent DNA helicase PcrA 1141096 4433628 LACR_1222 Lactococcus lactis subsp. cremoris SK11 ATP-dependent DNA helicase PcrA YP_809175.1 1138820 D 272622 CDS YP_809176.1 116511960 4433630 1141634..1142206 1 NC_008527.1 DNA-3-methyladenine glycosylase I 1142206 4433630 LACR_1224 Lactococcus lactis subsp. cremoris SK11 DNA-3-methyladenine glycosylase I YP_809176.1 1141634 D 272622 CDS YP_809177.1 116511961 4433631 1142287..1142736 1 NC_008527.1 hypothetical protein 1142736 4433631 LACR_1225 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809177.1 1142287 D 272622 CDS YP_809178.1 116511962 4433632 1142912..1144420 1 NC_008527.1 Reduces fumarate to succinate in anaerobic bacterial respiration; fumarate reductase flavoprotein subunit 1144420 4433632 LACR_1226 Lactococcus lactis subsp. cremoris SK11 fumarate reductase flavoprotein subunit YP_809178.1 1142912 D 272622 CDS YP_809179.1 116511963 4433633 complement(1144518..1145408) 1 NC_008527.1 transposase 1145408 4433633 LACR_1227 Lactococcus lactis subsp. cremoris SK11 transposase YP_809179.1 1144518 R 272622 CDS YP_809180.1 116511964 4433634 1145560..1146498 1 NC_008527.1 phosphotransferase family protein 1146498 4433634 LACR_1228 Lactococcus lactis subsp. cremoris SK11 phosphotransferase family protein YP_809180.1 1145560 D 272622 CDS YP_809181.1 116511965 4433635 complement(1146620..1147630) 1 NC_008527.1 cell surface protein 1147630 4433635 LACR_1229 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_809181.1 1146620 R 272622 CDS YP_809182.1 116511966 4433636 complement(1147692..1147892) 1 NC_008527.1 hypothetical protein 1147892 4433636 LACR_1230 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809182.1 1147692 R 272622 CDS YP_809183.1 116511967 4433637 1148413..1148658 1 NC_008527.1 hypothetical protein 1148658 4433637 LACR_1231 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809183.1 1148413 D 272622 CDS YP_809184.1 116511968 4433638 1148842..1149141 1 NC_008527.1 hypothetical protein 1149141 4433638 LACR_1232 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809184.1 1148842 D 272622 CDS YP_809185.1 116511969 4433639 1149210..1149890 1 NC_008527.1 hypothetical protein 1149890 4433639 LACR_1233 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809185.1 1149210 D 272622 CDS YP_809186.1 116511970 4433640 1149945..1150169 1 NC_008527.1 hypothetical protein 1150169 4433640 LACR_1234 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809186.1 1149945 D 272622 CDS YP_809187.1 116511971 4433641 1150162..1150740 1 NC_008527.1 hypothetical protein 1150740 4433641 LACR_1235 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809187.1 1150162 D 272622 CDS YP_809188.1 116511972 4433642 1151076..1151789 1 NC_008527.1 hypothetical protein 1151789 4433642 LACR_1236 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809188.1 1151076 D 272622 CDS YP_809189.1 116511973 4433643 1151929..1152921 1 NC_008527.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1152921 truB 4433643 truB Lactococcus lactis subsp. cremoris SK11 tRNA pseudouridine synthase B YP_809189.1 1151929 D 272622 CDS YP_809190.1 116511974 4433644 1152953..1153855 1 NC_008527.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1153855 4433644 LACR_1238 Lactococcus lactis subsp. cremoris SK11 bifunctional riboflavin kinase/FMN adenylyltransferase YP_809190.1 1152953 D 272622 CDS YP_809191.1 116511975 4433645 1153941..1154912 1 NC_008527.1 L-lactate dehydrogenase 1154912 4433645 LACR_1239 Lactococcus lactis subsp. cremoris SK11 L-lactate dehydrogenase YP_809191.1 1153941 D 272622 CDS YP_809192.1 116511976 4433239 1155062..1156123 1 NC_008527.1 hypothetical protein 1156123 4433239 LACR_1240 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809192.1 1155062 D 272622 CDS YP_809193.1 116511977 4433240 1156116..1157009 1 NC_008527.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 1157009 murQ 4433240 murQ Lactococcus lactis subsp. cremoris SK11 N-acetylmuramic acid-6-phosphate etherase YP_809193.1 1156116 D 272622 CDS YP_809194.1 116511978 4433241 1157045..1158982 1 NC_008527.1 sucrose-specific PTS system IIBC component 1158982 4433241 LACR_1242 Lactococcus lactis subsp. cremoris SK11 sucrose-specific PTS system IIBC component YP_809194.1 1157045 D 272622 CDS YP_809195.1 116511979 4433242 1159044..1159895 1 NC_008527.1 transcriptional regulator 1159895 4433242 LACR_1243 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809195.1 1159044 D 272622 CDS YP_809196.1 116511980 4433243 1160028..1160786 1 NC_008527.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1160786 tpiA 4433243 tpiA Lactococcus lactis subsp. cremoris SK11 triosephosphate isomerase YP_809196.1 1160028 D 272622 CDS YP_809197.1 116511981 4433245 1161915..1162502 1 NC_008527.1 hypothetical protein 1162502 4433245 LACR_1246 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809197.1 1161915 D 272622 CDS YP_809198.1 116511982 4433247 1164131..1164658 1 NC_008527.1 transcriptional regulator 1164658 4433247 LACR_1248 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809198.1 1164131 D 272622 CDS YP_809199.1 116511983 4433248 1164848..1165987 1 NC_008527.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1165987 4433248 LACR_1249 Lactococcus lactis subsp. cremoris SK11 coproporphyrinogen III oxidase YP_809199.1 1164848 D 272622 CDS YP_809200.1 116511984 4433249 1166046..1166849 1 NC_008527.1 hypothetical protein 1166849 4433249 LACR_1250 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809200.1 1166046 D 272622 CDS YP_809201.1 116511985 4433250 1166824..1166955 1 NC_008527.1 hypothetical protein 1166955 4433250 LACR_1251 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809201.1 1166824 D 272622 CDS YP_809202.1 116511986 4433251 1166952..1167392 1 NC_008527.1 deoxycytidylate deaminase 1167392 4433251 LACR_1252 Lactococcus lactis subsp. cremoris SK11 deoxycytidylate deaminase YP_809202.1 1166952 D 272622 CDS YP_809203.1 116511987 4433252 1167494..1168222 1 NC_008527.1 Acyl-ACP thioesterase 1168222 4433252 LACR_1253 Lactococcus lactis subsp. cremoris SK11 Acyl-ACP thioesterase YP_809203.1 1167494 D 272622 CDS YP_809204.1 116511988 4433253 1168274..1169047 1 NC_008527.1 HAD family sugar phosphatase 1169047 4433253 LACR_1254 Lactococcus lactis subsp. cremoris SK11 HAD family sugar phosphatase YP_809204.1 1168274 D 272622 CDS YP_809205.1 116511989 4433254 1169188..1169805 1 NC_008527.1 hypothetical protein 1169805 4433254 LACR_1255 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809205.1 1169188 D 272622 CDS YP_809206.1 116511990 4433255 1170069..1171058 1 NC_008527.1 guanosine 5'-monophosphate oxidoreductase 1171058 4433255 LACR_1256 Lactococcus lactis subsp. cremoris SK11 guanosine 5'-monophosphate oxidoreductase YP_809206.1 1170069 D 272622 CDS YP_809207.1 116511991 4432396 complement(1171231..1172181) 1 NC_008527.1 glycosyltransferase 1172181 4432396 LACR_1257 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_809207.1 1171231 R 272622 CDS YP_809208.1 116511992 4432397 complement(1172258..1172392) 1 NC_008527.1 hypothetical protein 1172392 4432397 LACR_1258 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809208.1 1172258 R 272622 CDS YP_809209.1 116511993 4432398 complement(1172477..1173688) 1 NC_008527.1 hypothetical protein 1173688 4432398 LACR_1259 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809209.1 1172477 R 272622 CDS YP_809210.1 116511994 4432399 complement(1173709..1174206) 1 NC_008527.1 hypothetical protein 1174206 4432399 LACR_1260 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809210.1 1173709 R 272622 CDS YP_809211.1 116511995 4432400 complement(1174231..1174458) 1 NC_008527.1 hypothetical protein 1174458 4432400 LACR_1261 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809211.1 1174231 R 272622 CDS YP_809212.1 116511996 4432401 1174461..1174838 1 NC_008527.1 hypothetical protein 1174838 4432401 LACR_1262 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809212.1 1174461 D 272622 CDS YP_809213.1 116511997 4432402 complement(1174961..1175155) 1 NC_008527.1 hypothetical protein 1175155 4432402 LACR_1263 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809213.1 1174961 R 272622 CDS YP_809214.1 116511998 4432403 1175455..1176072 1 NC_008527.1 hypothetical protein 1176072 4432403 LACR_1264 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809214.1 1175455 D 272622 CDS YP_809215.1 116511999 4432404 1176433..1177026 1 NC_008527.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1177026 4432404 LACR_1265 Lactococcus lactis subsp. cremoris SK11 xanthine phosphoribosyltransferase YP_809215.1 1176433 D 272622 CDS YP_809216.1 116512000 4432405 1177084..1178367 1 NC_008527.1 xanthine/uracil permease 1178367 4432405 LACR_1266 Lactococcus lactis subsp. cremoris SK11 xanthine/uracil permease YP_809216.1 1177084 D 272622 CDS YP_809217.1 116512001 4432406 complement(1178424..1178708) 1 NC_008527.1 hypothetical protein 1178708 4432406 LACR_1267 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809217.1 1178424 R 272622 CDS YP_809218.1 116512002 4432407 complement(1178989..1179498) 1 NC_008527.1 rRNA methylase (SpoU class) 1179498 4432407 LACR_1268 Lactococcus lactis subsp. cremoris SK11 rRNA methylase (SpoU class) YP_809218.1 1178989 R 272622 CDS YP_809219.1 116512003 4432408 1179745..1179837 1 NC_008527.1 hypothetical protein 1179837 4432408 LACR_1269 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809219.1 1179745 D 272622 CDS YP_809220.1 116512004 4432409 1179915..1180436 1 NC_008527.1 dihydrofolate reductase 1180436 4432409 LACR_1270 Lactococcus lactis subsp. cremoris SK11 dihydrofolate reductase YP_809220.1 1179915 D 272622 CDS YP_809221.1 116512005 4432410 1180433..1180603 1 NC_008527.1 hypothetical protein 1180603 4432410 LACR_1271 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809221.1 1180433 D 272622 CDS YP_809222.1 116512006 4432411 1180685..1181920 1 NC_008527.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1181920 clpX 4432411 clpX Lactococcus lactis subsp. cremoris SK11 ATP-dependent protease ATP-binding subunit ClpX YP_809222.1 1180685 D 272622 CDS YP_809223.1 116512007 4432412 1181917..1182504 1 NC_008527.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1182504 engB 4432412 engB Lactococcus lactis subsp. cremoris SK11 ribosome biogenesis GTP-binding protein YsxC YP_809223.1 1181917 D 272622 CDS YP_809224.1 116512008 4432413 1182558..1182908 1 NC_008527.1 dihydroneopterin aldolase 1182908 4432413 LACR_1274 Lactococcus lactis subsp. cremoris SK11 dihydroneopterin aldolase YP_809224.1 1182558 D 272622 CDS YP_809225.1 116512009 4432311 1182988..1184037 1 NC_008527.1 GTP cyclohydrolase 1184037 4432311 LACR_1275 Lactococcus lactis subsp. cremoris SK11 GTP cyclohydrolase YP_809225.1 1182988 D 272622 CDS YP_809226.1 116512010 4432312 1184034..1185107 1 NC_008527.1 dihydropteroate synthase 1185107 4432312 LACR_1276 Lactococcus lactis subsp. cremoris SK11 dihydropteroate synthase YP_809226.1 1184034 D 272622 CDS YP_809227.1 116512011 4432313 1185110..1185610 1 NC_008527.1 hypothetical protein 1185610 4432313 LACR_1277 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809227.1 1185110 D 272622 CDS YP_809228.1 116512012 4432314 1185626..1186909 1 NC_008527.1 folylpolyglutamate synthase 1186909 4432314 LACR_1278 Lactococcus lactis subsp. cremoris SK11 folylpolyglutamate synthase YP_809228.1 1185626 D 272622 CDS YP_809229.1 116512013 4432315 1187038..1187676 1 NC_008527.1 deoxynucleoside kinase 1187676 4432315 LACR_1279 Lactococcus lactis subsp. cremoris SK11 deoxynucleoside kinase YP_809229.1 1187038 D 272622 CDS YP_809230.1 116512014 4432316 1187857..1189143 1 NC_008527.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1189143 4432316 LACR_1280 Lactococcus lactis subsp. cremoris SK11 homoserine dehydrogenase YP_809230.1 1187857 D 272622 CDS YP_809231.1 116512015 4432317 1189148..1190038 1 NC_008527.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1190038 4432317 LACR_1281 Lactococcus lactis subsp. cremoris SK11 homoserine kinase YP_809231.1 1189148 D 272622 CDS YP_809232.1 116512016 4432318 1190292..1190891 1 NC_008527.1 hypothetical protein 1190891 4432318 LACR_1282 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809232.1 1190292 D 272622 CDS YP_809233.1 116512017 4432319 1190934..1191833 1 NC_008527.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1191833 murB 4432319 murB Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylenolpyruvoylglucosamine reductase YP_809233.1 1190934 D 272622 CDS YP_809234.1 116512018 4432320 1192293..1193573 1 NC_008527.1 ABC-type spermidine/putrescine transport system, ATPase component 1193573 4432320 LACR_1284 Lactococcus lactis subsp. cremoris SK11 ABC-type spermidine/putrescine transport system, ATPase component YP_809234.1 1192293 D 272622 CDS YP_809235.1 116512019 4432321 1193570..1194358 1 NC_008527.1 spermidine/putrescine ABC transporter permease protein 1194358 4432321 LACR_1285 Lactococcus lactis subsp. cremoris SK11 spermidine/putrescine ABC transporter permease protein YP_809235.1 1193570 D 272622 CDS YP_809236.1 116512020 4432322 1194360..1195160 1 NC_008527.1 spermidine/putrescine ABC transporter permease protein 1195160 4432322 LACR_1286 Lactococcus lactis subsp. cremoris SK11 spermidine/putrescine ABC transporter permease protein YP_809236.1 1194360 D 272622 CDS YP_809237.1 116512021 4432323 1195208..1196275 1 NC_008527.1 spermidine/putrescine-binding periplasmic protein 1196275 4432323 LACR_1287 Lactococcus lactis subsp. cremoris SK11 spermidine/putrescine-binding periplasmic protein YP_809237.1 1195208 D 272622 CDS YP_809238.1 116512022 4432324 complement(1196585..1197484) 1 NC_008527.1 AraC family transcriptional regulator 1197484 4432324 LACR_1288 Lactococcus lactis subsp. cremoris SK11 AraC family transcriptional regulator YP_809238.1 1196585 R 272622 CDS YP_809239.1 116512023 4432325 complement(1197484..1198680) 1 NC_008527.1 major facilitator superfamily permease 1198680 4432325 LACR_1289 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_809239.1 1197484 R 272622 CDS YP_809240.1 116512024 4432326 1198977..1200158 1 NC_008527.1 endoglucanase 1200158 4432326 LACR_1290 Lactococcus lactis subsp. cremoris SK11 endoglucanase YP_809240.1 1198977 D 272622 CDS YP_809241.1 116512025 4432327 1200191..1201852 1 NC_008527.1 Beta-xylosidase 1201852 4432327 LACR_1291 Lactococcus lactis subsp. cremoris SK11 Beta-xylosidase YP_809241.1 1200191 D 272622 CDS YP_809242.1 116512026 4433927 complement(1202346..1203200) 1 NC_008527.1 transposase 1203200 4433927 LACR_1292 Lactococcus lactis subsp. cremoris SK11 transposase YP_809242.1 1202346 R 272622 CDS YP_809243.1 116512027 4433928 complement(1203197..1203457) 1 NC_008527.1 transposase 1203457 4433928 LACR_1293 Lactococcus lactis subsp. cremoris SK11 transposase YP_809243.1 1203197 R 272622 CDS YP_809244.1 116512028 4433929 1204169..1205236 1 NC_008527.1 hypothetical protein 1205236 4433929 LACR_1294 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809244.1 1204169 D 272622 CDS YP_809245.1 116512029 4433930 1205399..1205731 1 NC_008527.1 ArsR family transcriptional regulator 1205731 4433930 LACR_1295 Lactococcus lactis subsp. cremoris SK11 ArsR family transcriptional regulator YP_809245.1 1205399 D 272622 CDS YP_809246.1 116512030 4433931 1205731..1206258 1 NC_008527.1 putative intracellular protease/amidase 1206258 4433931 LACR_1296 Lactococcus lactis subsp. cremoris SK11 putative intracellular protease/amidase YP_809246.1 1205731 D 272622 CDS YP_809247.1 116512031 4433932 1206407..1207324 1 NC_008527.1 saccharopine dehydrogenase related protein 1207324 4433932 LACR_1297 Lactococcus lactis subsp. cremoris SK11 saccharopine dehydrogenase related protein YP_809247.1 1206407 D 272622 CDS YP_809248.1 116512032 4433935 1208494..1208724 1 NC_008527.1 hypothetical protein 1208724 4433935 LACR_1300 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809248.1 1208494 D 272622 CDS YP_809249.1 116512033 4433936 1208903..1209610 1 NC_008527.1 hypothetical protein 1209610 4433936 LACR_1301 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809249.1 1208903 D 272622 CDS YP_809250.1 116512034 4433937 1210214..1211284 1 NC_008527.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1211284 xerS 4433937 xerS Lactococcus lactis subsp. cremoris SK11 site-specific tyrosine recombinase XerS YP_809250.1 1210214 D 272622 CDS YP_809251.1 116512035 4433938 complement(1211334..1212680) 1 NC_008527.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 1212680 4433938 LACR_1303 Lactococcus lactis subsp. cremoris SK11 tRNA (uracil-5-)-methyltransferase Gid YP_809251.1 1211334 R 272622 CDS YP_809252.1 116512036 4433939 complement(1212752..1214878) 1 NC_008527.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1214878 4433939 LACR_1304 Lactococcus lactis subsp. cremoris SK11 DNA topoisomerase I YP_809252.1 1212752 R 272622 CDS YP_809253.1 116512037 4433940 complement(1215144..1215992) 1 NC_008527.1 Rossmann fold nucleotide-binding protein for DNA uptake 1215992 4433940 LACR_1305 Lactococcus lactis subsp. cremoris SK11 Rossmann fold nucleotide-binding protein for DNA uptake YP_809253.1 1215144 R 272622 CDS YP_809254.1 116512038 4433941 complement(1216141..1216521) 1 NC_008527.1 endoribonuclease L-PSP 1216521 4433941 LACR_1306 Lactococcus lactis subsp. cremoris SK11 endoribonuclease L-PSP YP_809254.1 1216141 R 272622 CDS YP_809255.1 116512039 4433942 complement(1216561..1217271) 1 NC_008527.1 Alpha-acetolactate decarboxylase 1217271 4433942 LACR_1307 Lactococcus lactis subsp. cremoris SK11 Alpha-acetolactate decarboxylase YP_809255.1 1216561 R 272622 CDS YP_809256.1 116512040 4433944 complement(1218714..1219736) 1 NC_008527.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1219736 4433944 LACR_1309 Lactococcus lactis subsp. cremoris SK11 ketol-acid reductoisomerase YP_809256.1 1218714 R 272622 CDS YP_809257.1 116512041 4432464 complement(1219782..1220258) 1 NC_008527.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1220258 ilvH 4432464 ilvH Lactococcus lactis subsp. cremoris SK11 acetolactate synthase 3 regulatory subunit YP_809257.1 1219782 R 272622 CDS YP_809258.1 116512042 4432465 complement(1220251..1221975) 1 NC_008527.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 1221975 4432465 LACR_1311 Lactococcus lactis subsp. cremoris SK11 acetolactate synthase catalytic subunit YP_809258.1 1220251 R 272622 CDS YP_809259.1 116512043 4432466 complement(1221986..1223698) 1 NC_008527.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1223698 4432466 LACR_1312 Lactococcus lactis subsp. cremoris SK11 dihydroxy-acid dehydratase YP_809259.1 1221986 R 272622 CDS YP_809260.1 116512044 4432467 complement(1223818..1224600) 1 NC_008527.1 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA 1224600 4432467 LACR_1313 Lactococcus lactis subsp. cremoris SK11 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA YP_809260.1 1223818 R 272622 CDS YP_809261.1 116512045 4432469 1225155..1226045 1 NC_008527.1 transposase 1226045 4432469 LACR_1315 Lactococcus lactis subsp. cremoris SK11 transposase YP_809261.1 1225155 D 272622 CDS YP_809262.1 116512046 4432470 complement(1226238..1226771) 1 NC_008527.1 hypothetical protein 1226771 4432470 LACR_1316 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809262.1 1226238 R 272622 CDS YP_809263.1 116512047 4432471 complement(1226771..1228147) 1 NC_008527.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1228147 4432471 LACR_1317 Lactococcus lactis subsp. cremoris SK11 isopropylmalate isomerase large subunit YP_809263.1 1226771 R 272622 CDS YP_809264.1 116512048 4432472 complement(1228204..1228656) 1 NC_008527.1 hypothetical protein 1228656 4432472 LACR_1318 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809264.1 1228204 R 272622 CDS YP_809265.1 116512049 4432473 complement(1228699..1229145) 1 NC_008527.1 ADP-ribose pyrophosphatase 1229145 4432473 LACR_1319 Lactococcus lactis subsp. cremoris SK11 ADP-ribose pyrophosphatase YP_809265.1 1228699 R 272622 CDS YP_809266.1 116512050 4432474 complement(1229147..1230178) 1 NC_008527.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1230178 4432474 LACR_1320 Lactococcus lactis subsp. cremoris SK11 3-isopropylmalate dehydrogenase YP_809266.1 1229147 R 272622 CDS YP_809267.1 116512051 4432475 complement(1230319..1231110) 1 NC_008527.1 hypothetical protein 1231110 4432475 LACR_1321 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809267.1 1230319 R 272622 CDS YP_809268.1 116512052 4432476 complement(1231137..1231622) 1 NC_008527.1 hypothetical protein 1231622 4432476 LACR_1322 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809268.1 1231137 R 272622 CDS YP_809269.1 116512053 4432477 complement(1231658..1233199) 1 NC_008527.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1233199 4432477 LACR_1323 Lactococcus lactis subsp. cremoris SK11 2-isopropylmalate synthase YP_809269.1 1231658 R 272622 CDS YP_809270.1 116512054 4432478 1233622..1234581 1 NC_008527.1 hypothetical protein 1234581 4432478 LACR_1324 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809270.1 1233622 D 272622 CDS YP_809271.1 116512055 4432479 complement(1234614..1235399) 1 NC_008527.1 histidinol-phosphate phosphatase 1235399 4432479 LACR_1325 Lactococcus lactis subsp. cremoris SK11 histidinol-phosphate phosphatase YP_809271.1 1234614 R 272622 CDS YP_809272.1 116512056 4432480 complement(1235400..1236038) 1 NC_008527.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 1236038 4432480 LACR_1326 Lactococcus lactis subsp. cremoris SK11 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein YP_809272.1 1235400 R 272622 CDS YP_809273.1 116512057 4433997 complement(1236035..1236814) 1 NC_008527.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1236814 4433997 LACR_1327 Lactococcus lactis subsp. cremoris SK11 imidazole glycerol phosphate synthase subunit HisF YP_809273.1 1236035 R 272622 CDS YP_809274.1 116512058 4433998 complement(1236783..1237523) 1 NC_008527.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1237523 4433998 LACR_1328 Lactococcus lactis subsp. cremoris SK11 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_809274.1 1236783 R 272622 CDS YP_809275.1 116512059 4433999 complement(1237523..1238131) 1 NC_008527.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1238131 hisH 4433999 hisH Lactococcus lactis subsp. cremoris SK11 imidazole glycerol phosphate synthase subunit HisH YP_809275.1 1237523 R 272622 CDS YP_809276.1 116512060 4434000 complement(1238176..1238856) 1 NC_008527.1 aminoglycoside phosphotransferase 1238856 4434000 LACR_1330 Lactococcus lactis subsp. cremoris SK11 aminoglycoside phosphotransferase YP_809276.1 1238176 R 272622 CDS YP_809277.1 116512061 4434001 complement(1238958..1239566) 1 NC_008527.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1239566 hisB 4434001 hisB Lactococcus lactis subsp. cremoris SK11 imidazoleglycerol-phosphate dehydratase YP_809277.1 1238958 R 272622 CDS YP_809278.1 116512062 4434002 complement(1239567..1240874) 1 NC_008527.1 histidinol dehydrogenase 1240874 4434002 LACR_1332 Lactococcus lactis subsp. cremoris SK11 histidinol dehydrogenase YP_809278.1 1239567 R 272622 CDS YP_809279.1 116512063 4434004 complement(1241481..1241699) 1 NC_008527.1 hypothetical protein 1241699 4434004 LACR_1334 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809279.1 1241481 R 272622 CDS YP_809280.1 116512064 4434005 complement(1241714..1242670) 1 NC_008527.1 ATP phosphoribosyltransferase regulatory subunit 1242670 4434005 LACR_1335 Lactococcus lactis subsp. cremoris SK11 ATP phosphoribosyltransferase regulatory subunit YP_809280.1 1241714 R 272622 CDS YP_809281.1 116512065 4434006 complement(1242670..1243740) 1 NC_008527.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1243740 4434006 LACR_1336 Lactococcus lactis subsp. cremoris SK11 histidinol-phosphate aminotransferase YP_809281.1 1242670 R 272622 CDS YP_809282.1 116512066 4434007 complement(1244270..1245061) 1 NC_008527.1 steroid 5-alpha reductase family protein 1245061 4434007 LACR_1337 Lactococcus lactis subsp. cremoris SK11 steroid 5-alpha reductase family protein YP_809282.1 1244270 R 272622 CDS YP_809283.1 116512067 4434009 complement(1246824..1247678) 1 NC_008527.1 transposase 1247678 4434009 LACR_1339 Lactococcus lactis subsp. cremoris SK11 transposase YP_809283.1 1246824 R 272622 CDS YP_809284.1 116512068 4434010 complement(1247906..1248268) 1 NC_008527.1 hypothetical protein 1248268 4434010 LACR_1340 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809284.1 1247906 R 272622 CDS YP_809285.1 116512069 4434011 complement(1248344..1248823) 1 NC_008527.1 tryptophan-rich sensory protein 1248823 4434011 LACR_1341 Lactococcus lactis subsp. cremoris SK11 tryptophan-rich sensory protein YP_809285.1 1248344 R 272622 CDS YP_809286.1 116512070 4434012 complement(1249142..1251145) 1 NC_008527.1 exoribonuclease R 1251145 4434012 LACR_1342 Lactococcus lactis subsp. cremoris SK11 exoribonuclease R YP_809286.1 1249142 R 272622 CDS YP_809287.1 116512071 4434013 complement(1251288..1252463) 1 NC_008527.1 transposase 1252463 4434013 LACR_1343 Lactococcus lactis subsp. cremoris SK11 transposase YP_809287.1 1251288 R 272622 CDS YP_809288.1 116512072 4434014 complement(1252672..1253004) 1 NC_008527.1 XRE family transcriptional regulator 1253004 4434014 LACR_1344 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_809288.1 1252672 R 272622 CDS YP_809289.1 116512073 4432090 1253585..1254475 1 NC_008527.1 transposase 1254475 4432090 LACR_1346 Lactococcus lactis subsp. cremoris SK11 transposase YP_809289.1 1253585 D 272622 CDS YP_809290.1 116512074 4432091 complement(1254791..1255189) 1 NC_008527.1 transcriptional regulator 1255189 4432091 LACR_1347 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809290.1 1254791 R 272622 CDS YP_809291.1 116512075 4432092 1255297..1256442 1 NC_008527.1 arabinose efflux permease 1256442 4432092 LACR_1348 Lactococcus lactis subsp. cremoris SK11 arabinose efflux permease YP_809291.1 1255297 D 272622 CDS YP_809292.1 116512076 4432093 complement(1256549..1258213) 1 NC_008527.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 1258213 4432093 LACR_1349 Lactococcus lactis subsp. cremoris SK11 acetolactate synthase YP_809292.1 1256549 R 272622 CDS YP_809293.1 116512077 4432094 complement(1258368..1259624) 1 NC_008527.1 TPR repeat-containing protein 1259624 4432094 LACR_1350 Lactococcus lactis subsp. cremoris SK11 TPR repeat-containing protein YP_809293.1 1258368 R 272622 CDS YP_809294.1 116512078 4432095 complement(1259652..1260824) 1 NC_008527.1 permease 1260824 4432095 LACR_1351 Lactococcus lactis subsp. cremoris SK11 permease YP_809294.1 1259652 R 272622 CDS YP_809295.1 116512079 4432096 complement(1260890..1261510) 1 NC_008527.1 hypothetical protein 1261510 4432096 LACR_1352 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809295.1 1260890 R 272622 CDS YP_809296.1 116512080 4432097 complement(1261512..1263119) 1 NC_008527.1 hypothetical protein 1263119 4432097 LACR_1353 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809296.1 1261512 R 272622 CDS YP_809297.1 116512081 4432098 complement(1263164..1264534) 1 NC_008527.1 tRNA (uracil-5-)-methyltransferase related enzyme 1264534 4432098 LACR_1354 Lactococcus lactis subsp. cremoris SK11 tRNA (uracil-5-)-methyltransferase related enzyme YP_809297.1 1263164 R 272622 CDS YP_809298.1 116512082 4432099 complement(1264597..1265418) 1 NC_008527.1 transcriptional regulator 1265418 4432099 LACR_1355 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809298.1 1264597 R 272622 CDS YP_809299.1 116512083 4432100 1265556..1266260 1 NC_008527.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1266260 4432100 LACR_1356 Lactococcus lactis subsp. cremoris SK11 N-acetylmannosamine-6-phosphate 2-epimerase YP_809299.1 1265556 D 272622 CDS YP_809300.1 116512084 4432101 complement(1266600..1267322) 1 NC_008527.1 transposase 1267322 4432101 LACR_1357 Lactococcus lactis subsp. cremoris SK11 transposase YP_809300.1 1266600 R 272622 CDS YP_809301.1 116512085 4432102 complement(1267441..1267701) 1 NC_008527.1 transposase 1267701 4432102 LACR_1358 Lactococcus lactis subsp. cremoris SK11 transposase YP_809301.1 1267441 R 272622 CDS YP_809302.1 116512086 4432103 complement(1267738..1270083) 1 NC_008527.1 cation transport ATPase 1270083 4432103 LACR_1359 Lactococcus lactis subsp. cremoris SK11 cation transport ATPase YP_809302.1 1267738 R 272622 CDS YP_809303.1 116512087 4432104 1270251..1271426 1 NC_008527.1 transposase 1271426 4432104 LACR_1360 Lactococcus lactis subsp. cremoris SK11 transposase YP_809303.1 1270251 D 272622 CDS YP_809304.1 116512088 4432105 complement(1271780..1272637) 1 NC_008527.1 aldo/keto reductase 1272637 4432105 LACR_1361 Lactococcus lactis subsp. cremoris SK11 aldo/keto reductase YP_809304.1 1271780 R 272622 CDS YP_809305.1 116512089 4432551 1272809..1273219 1 NC_008527.1 transcriptional regulator 1273219 4432551 LACR_1362 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809305.1 1272809 D 272622 CDS YP_809306.1 116512090 4432552 complement(1273584..1274000) 1 NC_008527.1 arsenate reductase 1274000 4432552 LACR_1363 Lactococcus lactis subsp. cremoris SK11 arsenate reductase YP_809306.1 1273584 R 272622 CDS YP_809307.1 116512091 4432553 1274299..1274559 1 NC_008527.1 transposase 1274559 4432553 LACR_1364 Lactococcus lactis subsp. cremoris SK11 transposase YP_809307.1 1274299 D 272622 CDS YP_809308.1 116512092 4432554 1274556..1275410 1 NC_008527.1 transposase 1275410 4432554 LACR_1365 Lactococcus lactis subsp. cremoris SK11 transposase YP_809308.1 1274556 D 272622 CDS YP_809309.1 116512093 4432555 complement(1275462..1275770) 1 NC_008527.1 hypothetical protein 1275770 4432555 LACR_1366 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809309.1 1275462 R 272622 CDS YP_809310.1 116512094 4432556 complement(1276315..1277172) 1 NC_008527.1 5,10-methylenetetrahydrofolate reductase 1277172 4432556 LACR_1367 Lactococcus lactis subsp. cremoris SK11 5,10-methylenetetrahydrofolate reductase YP_809310.1 1276315 R 272622 CDS YP_809311.1 116512095 4432557 complement(1277162..1279435) 1 NC_008527.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1279435 4432557 LACR_1368 Lactococcus lactis subsp. cremoris SK11 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_809311.1 1277162 R 272622 CDS YP_809312.1 116512096 4432558 complement(1279595..1280248) 1 NC_008527.1 Mn-dependent transcriptional regulator 1280248 4432558 LACR_1369 Lactococcus lactis subsp. cremoris SK11 Mn-dependent transcriptional regulator YP_809312.1 1279595 R 272622 CDS YP_809313.1 116512097 4432559 complement(1280341..1283073) 1 NC_008527.1 cation-transporting P-ATPase 1283073 4432559 LACR_1370 Lactococcus lactis subsp. cremoris SK11 cation-transporting P-ATPase YP_809313.1 1280341 R 272622 CDS YP_809314.1 116512098 4432560 complement(1283548..1284834) 1 NC_008527.1 D-alanyl transfer protein 1284834 4432560 LACR_1371 Lactococcus lactis subsp. cremoris SK11 D-alanyl transfer protein YP_809314.1 1283548 R 272622 CDS YP_809315.1 116512099 4432561 complement(1284824..1285063) 1 NC_008527.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 1285063 4432561 LACR_1372 Lactococcus lactis subsp. cremoris SK11 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_809315.1 1284824 R 272622 CDS YP_809316.1 116512100 4432562 complement(1285099..1286322) 1 NC_008527.1 D-alanyl transfer protein 1286322 4432562 LACR_1373 Lactococcus lactis subsp. cremoris SK11 D-alanyl transfer protein YP_809316.1 1285099 R 272622 CDS YP_809317.1 116512101 4432563 complement(1286322..1287821) 1 NC_008527.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 1287821 4432563 LACR_1374 Lactococcus lactis subsp. cremoris SK11 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_809317.1 1286322 R 272622 CDS YP_809318.1 116512102 4432564 complement(1288159..1288815) 1 NC_008527.1 thiamine monophosphate synthase 1288815 4432564 LACR_1375 Lactococcus lactis subsp. cremoris SK11 thiamine monophosphate synthase YP_809318.1 1288159 R 272622 CDS YP_809319.1 116512103 4432565 complement(1288808..1289608) 1 NC_008527.1 phosphomethylpyrimidine kinase 1289608 4432565 LACR_1376 Lactococcus lactis subsp. cremoris SK11 phosphomethylpyrimidine kinase YP_809319.1 1288808 R 272622 CDS YP_809320.1 116512104 4432566 complement(1289621..1290373) 1 NC_008527.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 1290373 4432566 LACR_1377 Lactococcus lactis subsp. cremoris SK11 hydroxyethylthiazole kinase YP_809320.1 1289621 R 272622 CDS YP_809321.1 116512105 4432568 complement(1291542..1291637) 1 NC_008527.1 hypothetical protein 1291637 4432568 LACR_1379 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809321.1 1291542 R 272622 CDS YP_809322.1 116512106 4433159 complement(1291713..1292603) 1 NC_008527.1 transposase 1292603 4433159 LACR_1380 Lactococcus lactis subsp. cremoris SK11 transposase YP_809322.1 1291713 R 272622 CDS YP_809323.1 116512107 4433161 complement(1293911..1294747) 1 NC_008527.1 hypothetical protein 1294747 4433161 LACR_1382 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809323.1 1293911 R 272622 CDS YP_809324.1 116512108 4433162 complement(1294744..1296303) 1 NC_008527.1 major facilitator superfamily permease 1296303 4433162 LACR_1383 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_809324.1 1294744 R 272622 CDS YP_809326.1 116512110 4433165 complement(1297117..1297482) 1 NC_008527.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1297482 rplL 4433165 rplL Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L7/L12 YP_809326.1 1297117 R 272622 CDS YP_809327.1 116512111 4433166 complement(1297552..1298067) 1 NC_008527.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1298067 rplJ 4433166 rplJ Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L10 YP_809327.1 1297552 R 272622 CDS YP_809328.1 116512112 4433167 complement(1298321..1298746) 1 NC_008527.1 hypothetical protein 1298746 4433167 LACR_1388 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809328.1 1298321 R 272622 CDS YP_809329.1 116512113 4433168 complement(1298994..1299182) 1 NC_008527.1 hypothetical protein 1299182 4433168 LACR_1389 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809329.1 1298994 R 272622 CDS YP_809330.1 116512114 4433169 complement(1299196..1299954) 1 NC_008527.1 transcriptional regulator 1299954 4433169 LACR_1390 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809330.1 1299196 R 272622 CDS YP_809331.1 116512115 4433170 complement(1300073..1301857) 1 NC_008527.1 ABC transporter permease 1301857 4433170 LACR_1391 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease YP_809331.1 1300073 R 272622 CDS YP_809332.1 116512116 4433172 complement(1303796..1305046) 1 NC_008527.1 hypothetical protein 1305046 4433172 LACR_1393 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809332.1 1303796 R 272622 CDS YP_809333.1 116512117 4433174 complement(1306612..1307232) 1 NC_008527.1 hypothetical protein 1307232 4433174 LACR_1395 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809333.1 1306612 R 272622 CDS YP_809334.1 116512118 4433175 complement(1307581..1308300) 1 NC_008527.1 ribosomal large subunit pseudouridine synthase B 1308300 4433175 LACR_1396 Lactococcus lactis subsp. cremoris SK11 ribosomal large subunit pseudouridine synthase B YP_809334.1 1307581 R 272622 CDS YP_809335.1 116512119 4434051 complement(1308287..1308853) 1 NC_008527.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1308853 scpB 4434051 scpB Lactococcus lactis subsp. cremoris SK11 segregation and condensation protein B YP_809335.1 1308287 R 272622 CDS YP_809336.1 116512120 4434052 complement(1308846..1309574) 1 NC_008527.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1309574 scpA 4434052 scpA Lactococcus lactis subsp. cremoris SK11 segregation and condensation protein A YP_809336.1 1308846 R 272622 CDS YP_809337.1 116512121 4434053 complement(1309605..1310351) 1 NC_008527.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein 1310351 xerD 4434053 xerD Lactococcus lactis subsp. cremoris SK11 site-specific tyrosine recombinase XerD-like protein YP_809337.1 1309605 R 272622 CDS YP_809338.1 116512122 4434054 complement(1310299..1310760) 1 NC_008527.1 hypothetical protein 1310760 4434054 LACR_1400 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809338.1 1310299 R 272622 CDS YP_809339.1 116512123 4434055 complement(1310791..1311294) 1 NC_008527.1 hypothetical protein 1311294 4434055 LACR_1401 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809339.1 1310791 R 272622 CDS YP_809340.1 116512124 4434056 complement(1311333..1311938) 1 NC_008527.1 hypothetical protein 1311938 4434056 LACR_1402 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809340.1 1311333 R 272622 CDS YP_809341.1 116512125 4434057 complement(1311939..1312754) 1 NC_008527.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1312754 4434057 LACR_1403 Lactococcus lactis subsp. cremoris SK11 glutamate racemase YP_809341.1 1311939 R 272622 CDS YP_809342.1 116512126 4434058 complement(1312930..1313169) 1 NC_008527.1 hypothetical protein 1313169 4434058 LACR_1404 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809342.1 1312930 R 272622 CDS YP_809343.1 116512127 4434059 complement(1313320..1314579) 1 NC_008527.1 diaminopimelate decarboxylase 1314579 4434059 LACR_1405 Lactococcus lactis subsp. cremoris SK11 diaminopimelate decarboxylase YP_809343.1 1313320 R 272622 CDS YP_809344.1 116512128 4434060 complement(1314694..1316133) 1 NC_008527.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 1316133 gltD 4434060 gltD Lactococcus lactis subsp. cremoris SK11 glutamate synthase subunit beta YP_809344.1 1314694 R 272622 CDS YP_809345.1 116512129 4434061 complement(1316133..1320602) 1 NC_008527.1 glutamate synthase (NADH) large subunit 1320602 4434061 LACR_1407 Lactococcus lactis subsp. cremoris SK11 glutamate synthase (NADH) large subunit YP_809345.1 1316133 R 272622 CDS YP_809346.1 116512130 4434062 1320771..1321382 1 NC_008527.1 acetyltransferase 1321382 4434062 LACR_1408 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_809346.1 1320771 D 272622 CDS YP_809347.1 116512131 4434063 complement(1321415..1322437) 1 NC_008527.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1322437 4434063 LACR_1409 Lactococcus lactis subsp. cremoris SK11 branched-chain amino acid aminotransferase YP_809347.1 1321415 R 272622 CDS YP_809348.1 116512132 4434064 1322597..1323352 1 NC_008527.1 hypothetical protein 1323352 4434064 LACR_1410 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809348.1 1322597 D 272622 CDS YP_809349.1 116512133 4434066 complement(1324838..1326349) 1 NC_008527.1 glutamate gamma-aminobutyrate antiporter 1326349 4434066 LACR_1412 Lactococcus lactis subsp. cremoris SK11 glutamate gamma-aminobutyrate antiporter YP_809349.1 1324838 R 272622 CDS YP_809350.1 116512134 4434067 complement(1326392..1327282) 1 NC_008527.1 transcriptional regulator 1327282 4434067 LACR_1413 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809350.1 1326392 R 272622 CDS YP_809351.1 116512135 4434068 complement(1327759..1328649) 1 NC_008527.1 transposase 1328649 4434068 LACR_1414 Lactococcus lactis subsp. cremoris SK11 transposase YP_809351.1 1327759 R 272622 CDS YP_809352.1 116512136 4434338 complement(1328883..1329659) 1 NC_008527.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1329659 rnhB 4434338 rnhB Lactococcus lactis subsp. cremoris SK11 ribonuclease HII YP_809352.1 1328883 R 272622 CDS YP_809353.1 116512137 4434339 complement(1329772..1330623) 1 NC_008527.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1330623 rbgA 4434339 rbgA Lactococcus lactis subsp. cremoris SK11 ribosomal biogenesis GTPase YP_809353.1 1329772 R 272622 CDS YP_809354.1 116512138 4434340 complement(1330717..1331964) 1 NC_008527.1 integrase 1331964 4434340 LACR_1417 Lactococcus lactis subsp. cremoris SK11 integrase YP_809354.1 1330717 R 272622 CDS YP_809355.1 116512139 4434341 complement(1332044..1332292) 1 NC_008527.1 hypothetical protein 1332292 4434341 LACR_1418 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809355.1 1332044 R 272622 CDS YP_809356.1 116512140 4434342 complement(1332347..1333201) 1 NC_008527.1 hypothetical protein 1333201 4434342 LACR_1419 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809356.1 1332347 R 272622 CDS YP_809357.1 116512141 4434343 complement(1333279..1334751) 1 NC_008527.1 DNA segregation ATPase FtsK/SpoIIIE related protein 1334751 4434343 LACR_1420 Lactococcus lactis subsp. cremoris SK11 DNA segregation ATPase FtsK/SpoIIIE related protein YP_809357.1 1333279 R 272622 CDS YP_809358.1 116512142 4434344 complement(1334748..1335023) 1 NC_008527.1 hypothetical protein 1335023 4434344 LACR_1421 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809358.1 1334748 R 272622 CDS YP_809359.1 116512143 4434345 complement(1334992..1335432) 1 NC_008527.1 hypothetical protein 1335432 4434345 LACR_1422 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809359.1 1334992 R 272622 CDS YP_809360.1 116512144 4434346 complement(1335588..1336400) 1 NC_008527.1 hypothetical protein 1336400 4434346 LACR_1423 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809360.1 1335588 R 272622 CDS YP_809361.1 116512145 4434347 complement(1336402..1339986) 1 NC_008527.1 Type I restriction-modification system methyltransferase subunit 1339986 4434347 LACR_1424 Lactococcus lactis subsp. cremoris SK11 Type I restriction-modification system methyltransferase subunit YP_809361.1 1336402 R 272622 CDS YP_809362.1 116512146 4434348 complement(1340654..1341172) 1 NC_008527.1 acetyltransferase 1341172 4434348 LACR_1425 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_809362.1 1340654 R 272622 CDS YP_809363.1 116512147 4434350 1342729..1343490 1 NC_008527.1 DeoR family transcriptional regulator 1343490 4434350 LACR_1427 Lactococcus lactis subsp. cremoris SK11 DeoR family transcriptional regulator YP_809363.1 1342729 D 272622 CDS YP_809364.1 116512148 4434351 1343483..1344868 1 NC_008527.1 hypothetical protein 1344868 4434351 LACR_1428 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809364.1 1343483 D 272622 CDS YP_809365.1 116512149 4434352 complement(1344937..1346664) 1 NC_008527.1 hypothetical protein 1346664 4434352 LACR_1429 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809365.1 1344937 R 272622 CDS YP_809366.1 116512150 4432729 complement(1349535..1350668) 1 NC_008527.1 endoglucanase Y 1350668 4432729 LACR_1432 Lactococcus lactis subsp. cremoris SK11 endoglucanase Y YP_809366.1 1349535 R 272622 CDS YP_809367.1 116512151 4432730 complement(1350670..1351524) 1 NC_008527.1 ABC-type maltose transport system, permease component 1351524 4432730 LACR_1433 Lactococcus lactis subsp. cremoris SK11 ABC-type maltose transport system, permease component YP_809367.1 1350670 R 272622 CDS YP_809368.1 116512152 4432732 complement(1352617..1353924) 1 NC_008527.1 ABC-type sugar transport system, periplasmic component 1353924 4432732 LACR_1435 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, periplasmic component YP_809368.1 1352617 R 272622 CDS YP_809369.1 116512153 4432733 complement(1353926..1354618) 1 NC_008527.1 hypothetical protein 1354618 4432733 LACR_1436 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809369.1 1353926 R 272622 CDS YP_809370.1 116512154 4432734 complement(1354656..1355546) 1 NC_008527.1 transposase 1355546 4432734 LACR_1437 Lactococcus lactis subsp. cremoris SK11 transposase YP_809370.1 1354656 R 272622 CDS YP_809371.1 116512155 4432736 complement(1356694..1357533) 1 NC_008527.1 ABC-type Mn2+/Zn2+ transport system, permease component 1357533 4432736 LACR_1439 Lactococcus lactis subsp. cremoris SK11 ABC-type Mn2+/Zn2+ transport system, permease component YP_809371.1 1356694 R 272622 CDS YP_809372.1 116512156 4432737 complement(1357540..1358253) 1 NC_008527.1 manganese ABC transporter ATP-binding protein 1358253 4432737 LACR_1440 Lactococcus lactis subsp. cremoris SK11 manganese ABC transporter ATP-binding protein YP_809372.1 1357540 R 272622 CDS YP_809373.1 116512157 4432738 1358543..1358956 1 NC_008527.1 hypothetical protein 1358956 4432738 LACR_1441 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809373.1 1358543 D 272622 CDS YP_809374.1 116512158 4432739 complement(1359035..1359265) 1 NC_008527.1 hypothetical protein 1359265 4432739 LACR_1442 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809374.1 1359035 R 272622 CDS YP_809375.1 116512159 4432740 complement(1359517..1362657) 1 NC_008527.1 ATPase for DNA repair 1362657 4432740 LACR_1443 Lactococcus lactis subsp. cremoris SK11 ATPase for DNA repair YP_809375.1 1359517 R 272622 CDS YP_809376.1 116512160 4432741 complement(1362660..1363832) 1 NC_008527.1 DNA repair exonuclease 1363832 4432741 LACR_1444 Lactococcus lactis subsp. cremoris SK11 DNA repair exonuclease YP_809376.1 1362660 R 272622 CDS YP_809377.1 116512161 4432742 complement(1363978..1364916) 1 NC_008527.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1364916 4432742 LACR_1445 Lactococcus lactis subsp. cremoris SK11 2-dehydropantoate 2-reductase YP_809377.1 1363978 R 272622 CDS YP_809378.1 116512162 4432743 complement(1365114..1365488) 1 NC_008527.1 arsenate reductase 1365488 4432743 LACR_1446 Lactococcus lactis subsp. cremoris SK11 arsenate reductase YP_809378.1 1365114 R 272622 CDS YP_809379.1 116512163 4432744 complement(1365710..1365859) 1 NC_008527.1 hypothetical protein 1365859 4432744 LACR_1447 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809379.1 1365710 R 272622 CDS YP_809380.1 116512164 4432745 complement(1366233..1369292) 1 NC_008527.1 hypothetical protein 1369292 4432745 LACR_1448 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809380.1 1366233 R 272622 CDS YP_809381.1 116512165 4432746 complement(1369635..1370078) 1 NC_008527.1 hypothetical protein 1370078 4432746 LACR_1449 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809381.1 1369635 R 272622 CDS YP_809382.1 116512166 4433208 1370383..1372005 1 NC_008527.1 fibronectin-binding protein 1372005 4433208 LACR_1450 Lactococcus lactis subsp. cremoris SK11 fibronectin-binding protein YP_809382.1 1370383 D 272622 CDS YP_809383.1 116512167 4433209 1372047..1372862 1 NC_008527.1 SAM-dependent methyltransferase 1372862 4433209 LACR_1451 Lactococcus lactis subsp. cremoris SK11 SAM-dependent methyltransferase YP_809383.1 1372047 D 272622 CDS YP_809384.1 116512168 4433210 1373044..1374564 1 NC_008527.1 ABC-type uncharacterized transport system, ATPase component 1374564 4433210 LACR_1452 Lactococcus lactis subsp. cremoris SK11 ABC-type uncharacterized transport system, ATPase component YP_809384.1 1373044 D 272622 CDS YP_809385.1 116512169 4433211 1374557..1375651 1 NC_008527.1 ABC-type uncharacterized transport system, permease component 1375651 4433211 LACR_1453 Lactococcus lactis subsp. cremoris SK11 ABC-type uncharacterized transport system, permease component YP_809385.1 1374557 D 272622 CDS YP_809386.1 116512170 4433212 1375648..1376601 1 NC_008527.1 ABC transporter permease 1376601 4433212 LACR_1454 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease YP_809386.1 1375648 D 272622 CDS YP_809387.1 116512171 4433213 complement(1376718..1377695) 1 NC_008527.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1377695 ldh 4433213 ldh Lactococcus lactis subsp. cremoris SK11 L-lactate dehydrogenase YP_809387.1 1376718 R 272622 CDS YP_809388.1 116512172 4433214 complement(1377813..1379321) 1 NC_008527.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1379321 4433214 LACR_1456 Lactococcus lactis subsp. cremoris SK11 pyruvate kinase YP_809388.1 1377813 R 272622 CDS YP_809389.1 116512173 4433215 complement(1379409..1380431) 1 NC_008527.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1380431 4433215 LACR_1457 Lactococcus lactis subsp. cremoris SK11 6-phosphofructokinase YP_809389.1 1379409 R 272622 CDS YP_809390.1 116512174 4433216 complement(1380819..1381967) 1 NC_008527.1 N-acetylglucosamine 6-phosphate deacetylase 1381967 4433216 LACR_1458 Lactococcus lactis subsp. cremoris SK11 N-acetylglucosamine 6-phosphate deacetylase YP_809390.1 1380819 R 272622 CDS YP_809391.1 116512175 4433217 complement(1382138..1383316) 1 NC_008527.1 hypothetical protein 1383316 4433217 LACR_1459 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809391.1 1382138 R 272622 CDS YP_809392.1 116512176 4433218 complement(1383458..1384084) 1 NC_008527.1 5-bromo-4-chloroindolyl phosphate hydrolysis protein 1384084 4433218 LACR_1460 Lactococcus lactis subsp. cremoris SK11 5-bromo-4-chloroindolyl phosphate hydrolysis protein YP_809392.1 1383458 R 272622 CDS YP_809393.1 116512177 4433219 1384275..1385303 1 NC_008527.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1385303 gpsA 4433219 gpsA Lactococcus lactis subsp. cremoris SK11 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_809393.1 1384275 D 272622 CDS YP_809394.1 116512178 4433220 1385345..1386286 1 NC_008527.1 UDP-glucose pyrophosphorylase 1386286 4433220 LACR_1462 Lactococcus lactis subsp. cremoris SK11 UDP-glucose pyrophosphorylase YP_809394.1 1385345 D 272622 CDS YP_809395.1 116512179 4433221 1386357..1386764 1 NC_008527.1 hypothetical protein 1386764 4433221 LACR_1463 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809395.1 1386357 D 272622 CDS YP_809396.1 116512180 4433222 1386761..1387291 1 NC_008527.1 hypothetical protein 1387291 4433222 LACR_1464 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809396.1 1386761 D 272622 CDS YP_809397.1 116512181 4433223 1387282..1388241 1 NC_008527.1 geranylgeranyl pyrophosphate synthase 1388241 4433223 LACR_1465 Lactococcus lactis subsp. cremoris SK11 geranylgeranyl pyrophosphate synthase YP_809397.1 1387282 D 272622 CDS YP_809398.1 116512182 4433224 1388238..1388954 1 NC_008527.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1388954 gidB 4433224 gidB Lactococcus lactis subsp. cremoris SK11 16S rRNA methyltransferase GidB YP_809398.1 1388238 D 272622 CDS YP_809399.1 116512183 4433576 complement(1389040..1389420) 1 NC_008527.1 hypothetical protein 1389420 4433576 LACR_1467 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809399.1 1389040 R 272622 CDS YP_809400.1 116512184 4433577 complement(1389422..1390135) 1 NC_008527.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1390135 4433577 LACR_1468 Lactococcus lactis subsp. cremoris SK11 orotidine 5'-phosphate decarboxylase YP_809400.1 1389422 R 272622 CDS YP_809401.1 116512185 4433578 complement(1390265..1391200) 1 NC_008527.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 1391200 4433578 LACR_1469 Lactococcus lactis subsp. cremoris SK11 dihydroorotate dehydrogenase 1B YP_809401.1 1390265 R 272622 CDS YP_809402.1 116512186 4433579 complement(1391431..1392219) 1 NC_008527.1 dihydroorotate oxidase B, electron transfer subunit 1392219 4433579 LACR_1470 Lactococcus lactis subsp. cremoris SK11 dihydroorotate oxidase B, electron transfer subunit YP_809402.1 1391431 R 272622 CDS YP_809403.1 116512187 4433580 complement(1392469..1393833) 1 NC_008527.1 major facilitator superfamily permease 1393833 4433580 LACR_1471 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_809403.1 1392469 R 272622 CDS YP_809404.1 116512188 4433581 complement(1394030..1394746) 1 NC_008527.1 GntR family transcriptional regulator 1394746 4433581 LACR_1472 Lactococcus lactis subsp. cremoris SK11 GntR family transcriptional regulator YP_809404.1 1394030 R 272622 CDS YP_809405.1 116512189 4433582 complement(1394817..1396244) 1 NC_008527.1 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase 1396244 4433582 LACR_1473 Lactococcus lactis subsp. cremoris SK11 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase YP_809405.1 1394817 R 272622 CDS YP_809406.1 116512190 4433583 complement(1396254..1396994) 1 NC_008527.1 3-oxoacyl-ACP reductase 1396994 4433583 LACR_1474 Lactococcus lactis subsp. cremoris SK11 3-oxoacyl-ACP reductase YP_809406.1 1396254 R 272622 CDS YP_809407.1 116512191 4433584 complement(1396995..1397540) 1 NC_008527.1 hypothetical protein 1397540 4433584 LACR_1475 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809407.1 1396995 R 272622 CDS YP_809408.1 116512192 4433585 complement(1397537..1398373) 1 NC_008527.1 ABC-type maltose transport system, permease component 1398373 4433585 LACR_1476 Lactococcus lactis subsp. cremoris SK11 ABC-type maltose transport system, permease component YP_809408.1 1397537 R 272622 CDS YP_809409.1 116512193 4433586 complement(1398373..1399326) 1 NC_008527.1 ABC-type sugar transport system, permease component 1399326 4433586 LACR_1477 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, permease component YP_809409.1 1398373 R 272622 CDS YP_809410.1 116512194 4433587 complement(1399364..1400683) 1 NC_008527.1 ABC-type sugar transport system, periplasmic component 1400683 4433587 LACR_1478 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, periplasmic component YP_809410.1 1399364 R 272622 CDS YP_809411.1 116512195 4433588 complement(1400796..1401725) 1 NC_008527.1 hypothetical protein 1401725 4433588 LACR_1479 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809411.1 1400796 R 272622 CDS YP_809412.1 116512196 4433590 1402929..1404140 1 NC_008527.1 hypothetical protein 1404140 4433590 LACR_1481 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809412.1 1402929 D 272622 CDS YP_809413.1 116512197 4433591 1404354..1405505 1 NC_008527.1 hypothetical protein 1405505 4433591 LACR_1482 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809413.1 1404354 D 272622 CDS YP_809414.1 116512198 4433592 1405502..1406287 1 NC_008527.1 beta-propeller domain-containing protein 1406287 4433592 LACR_1483 Lactococcus lactis subsp. cremoris SK11 beta-propeller domain-containing protein YP_809414.1 1405502 D 272622 CDS YP_809415.1 116512199 4433593 complement(1406322..1406855) 1 NC_008527.1 ribosomal large subunit pseudouridine synthase E 1406855 4433593 LACR_1484 Lactococcus lactis subsp. cremoris SK11 ribosomal large subunit pseudouridine synthase E YP_809415.1 1406322 R 272622 CDS YP_809416.1 116512200 4432611 1407155..1408672 1 NC_008527.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1408672 glpK 4432611 glpK Lactococcus lactis subsp. cremoris SK11 glycerol kinase YP_809416.1 1407155 D 272622 CDS YP_809417.1 116512201 4432612 1408725..1410302 1 NC_008527.1 glycerol-3-phosphate dehydrogenase 1410302 4432612 LACR_1486 Lactococcus lactis subsp. cremoris SK11 glycerol-3-phosphate dehydrogenase YP_809417.1 1408725 D 272622 CDS YP_809418.1 116512202 4432613 1410321..1411049 1 NC_008527.1 glycerol uptake facilitator 1411049 4432613 LACR_1487 Lactococcus lactis subsp. cremoris SK11 glycerol uptake facilitator YP_809418.1 1410321 D 272622 CDS YP_809419.1 116512203 4432614 complement(1411107..1411313) 1 NC_008527.1 hypothetical protein 1411313 4432614 LACR_1488 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809419.1 1411107 R 272622 CDS YP_809420.1 116512204 4432615 complement(1411310..1412269) 1 NC_008527.1 hypothetical protein 1412269 4432615 LACR_1489 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809420.1 1411310 R 272622 CDS YP_809421.1 116512205 4432616 complement(1412348..1413160) 1 NC_008527.1 hypothetical protein 1413160 4432616 LACR_1490 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809421.1 1412348 R 272622 CDS YP_809422.1 116512206 4432617 complement(1413141..1413476) 1 NC_008527.1 hypothetical protein 1413476 4432617 LACR_1491 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809422.1 1413141 R 272622 CDS YP_809423.1 116512207 4432618 complement(1413508..1413600) 1 NC_008527.1 hypothetical protein 1413600 4432618 LACR_1492 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809423.1 1413508 R 272622 CDS YP_809424.1 116512208 4432619 complement(1413792..1414382) 1 NC_008527.1 transposase 1414382 4432619 LACR_1493 Lactococcus lactis subsp. cremoris SK11 transposase YP_809424.1 1413792 R 272622 CDS YP_809425.1 116512209 4432620 complement(1414633..1414893) 1 NC_008527.1 transposase 1414893 4432620 LACR_1494 Lactococcus lactis subsp. cremoris SK11 transposase YP_809425.1 1414633 R 272622 CDS YP_809426.1 116512210 4432621 complement(1414914..1415573) 1 NC_008527.1 cell surface protein 1415573 4432621 LACR_1495 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_809426.1 1414914 R 272622 CDS YP_809427.1 116512211 4432622 complement(1415741..1417651) 1 NC_008527.1 hypothetical protein 1417651 4432622 LACR_1496 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809427.1 1415741 R 272622 CDS YP_809428.1 116512212 4432623 complement(1417727..1418308) 1 NC_008527.1 hypothetical protein 1418308 4432623 LACR_1497 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809428.1 1417727 R 272622 CDS YP_809429.1 116512213 4432624 complement(1418507..1421701) 1 NC_008527.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1421701 carB 4432624 carB Lactococcus lactis subsp. cremoris SK11 carbamoyl phosphate synthase large subunit YP_809429.1 1418507 R 272622 CDS YP_809430.1 116512214 4432625 complement(1422051..1422524) 1 NC_008527.1 glutathione peroxidase 1422524 4432625 LACR_1499 Lactococcus lactis subsp. cremoris SK11 glutathione peroxidase YP_809430.1 1422051 R 272622 CDS YP_809431.1 116512215 4432627 complement(1423423..1426056) 1 NC_008527.1 cation transport ATPase 1426056 4432627 LACR_1501 Lactococcus lactis subsp. cremoris SK11 cation transport ATPase YP_809431.1 1423423 R 272622 CDS YP_809432.1 116512216 4434233 complement(1426315..1427037) 1 NC_008527.1 hypothetical protein 1427037 4434233 LACR_1502 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809432.1 1426315 R 272622 CDS YP_809433.1 116512217 4434234 complement(1427260..1427691) 1 NC_008527.1 hypothetical protein 1427691 4434234 LACR_1503 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809433.1 1427260 R 272622 CDS YP_809434.1 116512218 4434235 complement(1427748..1428602) 1 NC_008527.1 transposase 1428602 4434235 LACR_1504 Lactococcus lactis subsp. cremoris SK11 transposase YP_809434.1 1427748 R 272622 CDS YP_809435.1 116512219 4434236 complement(1428599..1428859) 1 NC_008527.1 transposase 1428859 4434236 LACR_1505 Lactococcus lactis subsp. cremoris SK11 transposase YP_809435.1 1428599 R 272622 CDS YP_809436.1 116512220 4434237 1429287..1429868 1 NC_008527.1 hypothetical protein 1429868 4434237 LACR_1506 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809436.1 1429287 D 272622 CDS YP_809437.1 116512221 4434238 1430039..1430794 1 NC_008527.1 hypothetical protein 1430794 4434238 LACR_1507 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809437.1 1430039 D 272622 CDS YP_809438.1 116512222 4434239 complement(1430911..1431264) 1 NC_008527.1 hypothetical protein 1431264 4434239 LACR_1508 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809438.1 1430911 R 272622 CDS YP_809439.1 116512223 4434240 complement(1431415..1431843) 1 NC_008527.1 universal stress protein UspA-like nucleotide-binding protein 1431843 4434240 LACR_1509 Lactococcus lactis subsp. cremoris SK11 universal stress protein UspA-like nucleotide-binding protein YP_809439.1 1431415 R 272622 CDS YP_809440.1 116512224 4434241 1432090..1432374 1 NC_008527.1 hypothetical protein 1432374 4434241 LACR_1510 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809440.1 1432090 D 272622 CDS YP_809441.1 116512225 4434242 complement(1432573..1433121) 1 NC_008527.1 hypothetical protein 1433121 4434242 LACR_1511 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809441.1 1432573 R 272622 CDS YP_809442.1 116512226 4434243 complement(1433267..1433689) 1 NC_008527.1 lactoylglutathione lyase related lyase 1433689 4434243 LACR_1512 Lactococcus lactis subsp. cremoris SK11 lactoylglutathione lyase related lyase YP_809442.1 1433267 R 272622 CDS YP_809443.1 116512227 4434244 1434052..1434594 1 NC_008527.1 acetyltransferase 1434594 4434244 LACR_1513 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_809443.1 1434052 D 272622 CDS YP_809444.1 116512228 4434245 complement(1434687..1435466) 1 NC_008527.1 transposase 1435466 4434245 LACR_1514 Lactococcus lactis subsp. cremoris SK11 transposase YP_809444.1 1434687 R 272622 CDS YP_809445.1 116512229 4434246 complement(1435669..1436178) 1 NC_008527.1 hypothetical protein 1436178 4434246 LACR_1515 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809445.1 1435669 R 272622 CDS YP_809446.1 116512230 4434247 1436622..1437512 1 NC_008527.1 transposase 1437512 4434247 LACR_1516 Lactococcus lactis subsp. cremoris SK11 transposase YP_809446.1 1436622 D 272622 CDS YP_809447.1 116512231 4434248 1438103..1439011 1 NC_008527.1 hypothetical protein 1439011 4434248 LACR_1517 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809447.1 1438103 D 272622 CDS YP_809448.1 116512232 4434249 complement(1439201..1439995) 1 NC_008527.1 hypothetical protein 1439995 4434249 LACR_1518 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809448.1 1439201 R 272622 CDS YP_809449.1 116512233 4434250 complement(1440545..1441075) 1 NC_008527.1 hypothetical protein 1441075 4434250 LACR_1519 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809449.1 1440545 R 272622 CDS YP_809450.1 116512234 4434582 complement(1441135..1442025) 1 NC_008527.1 transposase 1442025 4434582 LACR_1520 Lactococcus lactis subsp. cremoris SK11 transposase YP_809450.1 1441135 R 272622 CDS YP_809451.1 116512235 4434584 complement(1442869..1443204) 1 NC_008527.1 putative DNA-binding protein 1443204 4434584 LACR_1522 Lactococcus lactis subsp. cremoris SK11 putative DNA-binding protein YP_809451.1 1442869 R 272622 CDS YP_809452.1 116512236 4434585 1443388..1444098 1 NC_008527.1 DNA-binding response regulator 1444098 4434585 LACR_1523 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_809452.1 1443388 D 272622 CDS YP_809453.1 116512237 4434586 1444088..1445641 1 NC_008527.1 Signal transduction histidine kinase 1445641 4434586 LACR_1524 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_809453.1 1444088 D 272622 CDS YP_809454.1 116512238 4434587 1445739..1446179 1 NC_008527.1 hypothetical protein 1446179 4434587 LACR_1525 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809454.1 1445739 D 272622 CDS YP_809455.1 116512239 4434588 complement(1446187..1446894) 1 NC_008527.1 GntR family transcriptional regulator 1446894 4434588 LACR_1526 Lactococcus lactis subsp. cremoris SK11 GntR family transcriptional regulator YP_809455.1 1446187 R 272622 CDS YP_809456.1 116512240 4434589 complement(1447081..1448136) 1 NC_008527.1 basic membrane protein A 1448136 4434589 LACR_1527 Lactococcus lactis subsp. cremoris SK11 basic membrane protein A YP_809456.1 1447081 R 272622 CDS YP_809457.1 116512241 4434590 complement(1448404..1448796) 1 NC_008527.1 cytidine deaminase 1448796 4434590 LACR_1528 Lactococcus lactis subsp. cremoris SK11 cytidine deaminase YP_809457.1 1448404 R 272622 CDS YP_809458.1 116512242 4434591 complement(1448783..1449445) 1 NC_008527.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1449445 4434591 LACR_1529 Lactococcus lactis subsp. cremoris SK11 deoxyribose-phosphate aldolase YP_809458.1 1448783 R 272622 CDS YP_809459.1 116512243 4434592 complement(1449458..1449646) 1 NC_008527.1 hypothetical protein 1449646 4434592 LACR_1530 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809459.1 1449458 R 272622 CDS YP_809460.1 116512244 4434593 complement(1449648..1450940) 1 NC_008527.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 1450940 4434593 LACR_1531 Lactococcus lactis subsp. cremoris SK11 pyrimidine-nucleoside phosphorylase YP_809460.1 1449648 R 272622 CDS YP_809461.1 116512245 4434594 complement(1450975..1451658) 1 NC_008527.1 16S RNA G1207 methylase RsmC 1451658 4434594 LACR_1532 Lactococcus lactis subsp. cremoris SK11 16S RNA G1207 methylase RsmC YP_809461.1 1450975 R 272622 CDS YP_809462.1 116512246 4434595 1451760..1452680 1 NC_008527.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1452680 4434595 LACR_1533 Lactococcus lactis subsp. cremoris SK11 pantothenate kinase YP_809462.1 1451760 D 272622 CDS YP_809463.1 116512247 4434596 complement(1452751..1453182) 1 NC_008527.1 phosphate-starvation-inducible protein PsiE 1453182 4434596 LACR_1534 Lactococcus lactis subsp. cremoris SK11 phosphate-starvation-inducible protein PsiE YP_809463.1 1452751 R 272622 CDS YP_809464.1 116512248 4434597 complement(1453236..1454180) 1 NC_008527.1 cation transporter 1454180 4434597 LACR_1535 Lactococcus lactis subsp. cremoris SK11 cation transporter YP_809464.1 1453236 R 272622 CDS YP_809465.1 116512249 4433528 complement(1454462..1454764) 1 NC_008527.1 XRE family transcriptional regulator 1454764 4433528 LACR_1536 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_809465.1 1454462 R 272622 CDS YP_809466.1 116512250 4433529 complement(1454794..1455336) 1 NC_008527.1 transcriptional regulator 1455336 4433529 LACR_1537 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809466.1 1454794 R 272622 CDS YP_809467.1 116512251 4433530 complement(1455318..1456640) 1 NC_008527.1 phosphoadenosine phosphosulfate sulfotransferase 1456640 4433530 LACR_1538 Lactococcus lactis subsp. cremoris SK11 phosphoadenosine phosphosulfate sulfotransferase YP_809467.1 1455318 R 272622 CDS YP_809468.1 116512252 4433531 1456906..1457256 1 NC_008527.1 transcription regulator 1457256 4433531 LACR_1539 Lactococcus lactis subsp. cremoris SK11 transcription regulator YP_809468.1 1456906 D 272622 CDS YP_809469.1 116512253 4433532 complement(1457537..1457707) 1 NC_008527.1 hypothetical protein 1457707 4433532 LACR_1540 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809469.1 1457537 R 272622 CDS YP_809470.1 116512254 4433533 complement(1457897..1459618) 1 NC_008527.1 ABC-type proline/glycine betaine transport system, permease component 1459618 4433533 LACR_1541 Lactococcus lactis subsp. cremoris SK11 ABC-type proline/glycine betaine transport system, permease component YP_809470.1 1457897 R 272622 CDS YP_809471.1 116512255 4433534 complement(1459611..1460834) 1 NC_008527.1 ABC-type proline/glycine betaine transport system, ATPase component 1460834 4433534 LACR_1542 Lactococcus lactis subsp. cremoris SK11 ABC-type proline/glycine betaine transport system, ATPase component YP_809471.1 1459611 R 272622 CDS YP_809472.1 116512256 4433535 complement(1461047..1461667) 1 NC_008527.1 GntR family transcriptional regulator 1461667 4433535 LACR_1543 Lactococcus lactis subsp. cremoris SK11 GntR family transcriptional regulator YP_809472.1 1461047 R 272622 CDS YP_809473.1 116512257 4433536 complement(1461833..1463269) 1 NC_008527.1 beta-glucosidase 1463269 4433536 LACR_1544 Lactococcus lactis subsp. cremoris SK11 beta-glucosidase YP_809473.1 1461833 R 272622 CDS YP_809474.1 116512258 4433538 complement(1465327..1466181) 1 NC_008527.1 beta-glucoside operon antiterminator 1466181 4433538 LACR_1546 Lactococcus lactis subsp. cremoris SK11 beta-glucoside operon antiterminator YP_809474.1 1465327 R 272622 CDS YP_809475.1 116512259 4433539 complement(1466272..1466382) 1 NC_008527.1 hypothetical protein 1466382 4433539 LACR_1547 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809475.1 1466272 R 272622 CDS YP_809476.1 116512260 4433540 complement(1466345..1467106) 1 NC_008527.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1467106 trpA 4433540 trpA Lactococcus lactis subsp. cremoris SK11 tryptophan synthase subunit alpha YP_809476.1 1466345 R 272622 CDS YP_809477.1 116512261 4433541 complement(1467106..1468311) 1 NC_008527.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1468311 4433541 LACR_1549 Lactococcus lactis subsp. cremoris SK11 tryptophan synthase subunit beta YP_809477.1 1467106 R 272622 CDS YP_809478.1 116512262 4433542 complement(1468410..1468928) 1 NC_008527.1 acetyltransferase 1468928 4433542 LACR_1550 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_809478.1 1468410 R 272622 CDS YP_809479.1 116512263 4433543 complement(1468918..1469976) 1 NC_008527.1 phosphoribosylanthranilate isomerase 1469976 4433543 LACR_1551 Lactococcus lactis subsp. cremoris SK11 phosphoribosylanthranilate isomerase YP_809479.1 1468918 R 272622 CDS YP_809480.1 116512264 4433544 complement(1469966..1470760) 1 NC_008527.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1470760 trpC 4433544 trpC Lactococcus lactis subsp. cremoris SK11 indole-3-glycerol-phosphate synthase YP_809480.1 1469966 R 272622 CDS YP_809481.1 116512265 4433545 complement(1470767..1471135) 1 NC_008527.1 lactoylglutathione lyase 1471135 4433545 LACR_1553 Lactococcus lactis subsp. cremoris SK11 lactoylglutathione lyase YP_809481.1 1470767 R 272622 CDS YP_809482.1 116512266 4434355 complement(1471373..1471579) 1 NC_008527.1 hypothetical protein 1471579 4434355 LACR_1554 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809482.1 1471373 R 272622 CDS YP_809483.1 116512267 4434356 complement(1471638..1471772) 1 NC_008527.1 hypothetical protein 1471772 4434356 LACR_1555 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809483.1 1471638 R 272622 CDS YP_809484.1 116512268 4434357 complement(1471744..1471998) 1 NC_008527.1 hypothetical protein 1471998 4434357 LACR_1556 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809484.1 1471744 R 272622 CDS YP_809485.1 116512269 4434358 complement(1472095..1472547) 1 NC_008527.1 hypothetical protein 1472547 4434358 LACR_1557 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809485.1 1472095 R 272622 CDS YP_809486.1 116512270 4434359 complement(1472745..1473752) 1 NC_008527.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1473752 trpD 4434359 trpD Lactococcus lactis subsp. cremoris SK11 anthranilate phosphoribosyltransferase YP_809486.1 1472745 R 272622 CDS YP_809487.1 116512271 4434360 complement(1473757..1474338) 1 NC_008527.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1474338 4434360 LACR_1559 Lactococcus lactis subsp. cremoris SK11 anthranilate synthase component II YP_809487.1 1473757 R 272622 CDS YP_809488.1 116512272 4434361 complement(1474390..1475760) 1 NC_008527.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1475760 4434361 LACR_1560 Lactococcus lactis subsp. cremoris SK11 anthranilate synthase component I YP_809488.1 1474390 R 272622 CDS YP_809489.1 116512273 4434362 complement(1476214..1476573) 1 NC_008527.1 hypothetical protein 1476573 4434362 LACR_1561 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809489.1 1476214 R 272622 CDS YP_809490.1 116512274 4434366 complement(1477740..1478483) 1 NC_008527.1 methylase for ubiquinone/menaquinone biosynthesis 1478483 4434366 LACR_1565 Lactococcus lactis subsp. cremoris SK11 methylase for ubiquinone/menaquinone biosynthesis YP_809490.1 1477740 R 272622 CDS YP_809491.1 116512275 4434367 complement(1478559..1479239) 1 NC_008527.1 hypothetical protein 1479239 4434367 LACR_1566 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809491.1 1478559 R 272622 CDS YP_809492.1 116512276 4434368 complement(1479239..1479928) 1 NC_008527.1 hypothetical protein 1479928 4434368 LACR_1567 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809492.1 1479239 R 272622 CDS YP_809493.1 116512277 4434369 1480055..1480441 1 NC_008527.1 Fe2+/Zn2+ uptake regulation protein 1480441 4434369 LACR_1568 Lactococcus lactis subsp. cremoris SK11 Fe2+/Zn2+ uptake regulation protein YP_809493.1 1480055 D 272622 CDS YP_809494.1 116512278 4434370 1480612..1481499 1 NC_008527.1 DMT family permease 1481499 4434370 LACR_1569 Lactococcus lactis subsp. cremoris SK11 DMT family permease YP_809494.1 1480612 D 272622 CDS YP_809495.1 116512279 4434371 complement(1481542..1481976) 1 NC_008527.1 transcriptional regulator 1481976 4434371 LACR_1570 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809495.1 1481542 R 272622 CDS YP_809496.1 116512280 4434598 1482053..1482784 1 NC_008527.1 Short-chain alcohol dehydrogenase of unknown specificity 1482784 4434598 LACR_1571 Lactococcus lactis subsp. cremoris SK11 Short-chain alcohol dehydrogenase of unknown specificity YP_809496.1 1482053 D 272622 CDS YP_809497.1 116512281 4434599 complement(1482894..1484693) 1 NC_008527.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1484693 4434599 LACR_1572 Lactococcus lactis subsp. cremoris SK11 1-deoxy-D-xylulose-5-phosphate synthase YP_809497.1 1482894 R 272622 CDS YP_809498.1 116512282 4434600 complement(1484956..1485375) 1 NC_008527.1 MarR family transcriptional regulator 1485375 4434600 LACR_1573 Lactococcus lactis subsp. cremoris SK11 MarR family transcriptional regulator YP_809498.1 1484956 R 272622 CDS YP_809499.1 116512283 4434601 1485552..1486376 1 NC_008527.1 cationic transporter 1486376 4434601 LACR_1574 Lactococcus lactis subsp. cremoris SK11 cationic transporter YP_809499.1 1485552 D 272622 CDS YP_809500.1 116512284 4434602 1486556..1487935 1 NC_008527.1 hypothetical protein 1487935 4434602 LACR_1575 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809500.1 1486556 D 272622 CDS YP_809501.1 116512285 4434603 complement(1487979..1488581) 1 NC_008527.1 hypothetical protein 1488581 4434603 LACR_1576 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809501.1 1487979 R 272622 CDS YP_809502.1 116512286 4434604 complement(1488587..1489510) 1 NC_008527.1 hypothetical protein 1489510 4434604 LACR_1577 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809502.1 1488587 R 272622 CDS YP_809503.1 116512287 4434605 complement(1489640..1490392) 1 NC_008527.1 hypothetical protein 1490392 4434605 LACR_1578 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809503.1 1489640 R 272622 CDS YP_809504.1 116512288 4434606 complement(1490415..1491113) 1 NC_008527.1 integral membrane protein 1491113 4434606 LACR_1579 Lactococcus lactis subsp. cremoris SK11 integral membrane protein YP_809504.1 1490415 R 272622 CDS YP_809505.1 116512289 4434607 complement(1491233..1492867) 1 NC_008527.1 ABC-type sugar transport system, periplasmic component 1492867 4434607 LACR_1580 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, periplasmic component YP_809505.1 1491233 R 272622 CDS YP_809506.1 116512290 4434608 complement(1492939..1493802) 1 NC_008527.1 ABC-type sugar transport system, permease component 1493802 4434608 LACR_1581 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, permease component YP_809506.1 1492939 R 272622 CDS YP_809507.1 116512291 4434610 complement(1495037..1496578) 1 NC_008527.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1496578 guaA 4434610 guaA Lactococcus lactis subsp. cremoris SK11 GMP synthase YP_809507.1 1495037 R 272622 CDS YP_809508.1 116512292 4434611 complement(1496788..1497663) 1 NC_008527.1 fructokinase 1497663 4434611 LACR_1584 Lactococcus lactis subsp. cremoris SK11 fructokinase YP_809508.1 1496788 R 272622 CDS YP_809509.1 116512293 4434612 complement(1497737..1498606) 1 NC_008527.1 transcriptional regulator/sugar kinase 1498606 4434612 LACR_1585 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator/sugar kinase YP_809509.1 1497737 R 272622 CDS YP_809510.1 116512294 4434613 complement(1498648..1500087) 1 NC_008527.1 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase 1500087 4434613 LACR_1586 Lactococcus lactis subsp. cremoris SK11 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase YP_809510.1 1498648 R 272622 CDS YP_809511.1 116512295 4434614 complement(1500121..1500729) 1 NC_008527.1 integral membrane protein 1500729 4434614 LACR_1587 Lactococcus lactis subsp. cremoris SK11 integral membrane protein YP_809511.1 1500121 R 272622 CDS YP_809512.1 116512296 4434615 complement(1500762..1500941) 1 NC_008527.1 hypothetical protein 1500941 4434615 LACR_1588 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809512.1 1500762 R 272622 CDS YP_809513.1 116512297 4434460 complement(1501032..1501727) 1 NC_008527.1 peptidase E 1501727 4434460 LACR_1589 Lactococcus lactis subsp. cremoris SK11 peptidase E YP_809513.1 1501032 R 272622 CDS YP_809514.1 116512298 4434461 complement(1501727..1501984) 1 NC_008527.1 phosphoribosylanthranilate isomerase 1501984 4434461 LACR_1590 Lactococcus lactis subsp. cremoris SK11 phosphoribosylanthranilate isomerase YP_809514.1 1501727 R 272622 CDS YP_809515.1 116512299 4434462 complement(1502170..1503024) 1 NC_008527.1 transposase 1503024 4434462 LACR_1591 Lactococcus lactis subsp. cremoris SK11 transposase YP_809515.1 1502170 R 272622 CDS YP_809516.1 116512300 4434463 complement(1503021..1503281) 1 NC_008527.1 transposase 1503281 4434463 LACR_1592 Lactococcus lactis subsp. cremoris SK11 transposase YP_809516.1 1503021 R 272622 CDS YP_809517.1 116512301 4434464 complement(1503412..1504461) 1 NC_008527.1 aldose 1-epimerase 1504461 4434464 LACR_1593 Lactococcus lactis subsp. cremoris SK11 aldose 1-epimerase YP_809517.1 1503412 R 272622 CDS YP_809518.1 116512302 4434466 complement(1506045..1506869) 1 NC_008527.1 xylanase 1506869 4434466 LACR_1595 Lactococcus lactis subsp. cremoris SK11 xylanase YP_809518.1 1506045 R 272622 CDS YP_809519.1 116512303 4434467 complement(1507014..1508183) 1 NC_008527.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1508183 4434467 LACR_1596 Lactococcus lactis subsp. cremoris SK11 xylose isomerase YP_809519.1 1507014 R 272622 CDS YP_809520.1 116512304 4434468 1508294..1509226 1 NC_008527.1 AraC family transcriptional regulator 1509226 4434468 LACR_1597 Lactococcus lactis subsp. cremoris SK11 AraC family transcriptional regulator YP_809520.1 1508294 D 272622 CDS YP_809521.1 116512305 4434469 complement(1509382..1510488) 1 NC_008527.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1510488 4434469 LACR_1598 Lactococcus lactis subsp. cremoris SK11 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_809521.1 1509382 R 272622 CDS YP_809522.1 116512306 4434470 complement(1510544..1511029) 1 NC_008527.1 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase 1511029 4434470 LACR_1599 Lactococcus lactis subsp. cremoris SK11 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase YP_809522.1 1510544 R 272622 CDS YP_809523.1 116512307 4434471 complement(1511026..1511754) 1 NC_008527.1 HAD superfamily hydrolase 1511754 4434471 LACR_1600 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_809523.1 1511026 R 272622 CDS YP_809524.1 116512308 4434472 complement(1511826..1513067) 1 NC_008527.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1513067 4434472 LACR_1601 Lactococcus lactis subsp. cremoris SK11 phosphoribosylamine--glycine ligase YP_809524.1 1511826 R 272622 CDS YP_809525.1 116512309 4434473 1513461..1514087 1 NC_008527.1 transcriptional regulator 1514087 4434473 LACR_1602 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809525.1 1513461 D 272622 CDS YP_809526.1 116512310 4434474 1514191..1515588 1 NC_008527.1 major facilitator superfamily permease 1515588 4434474 LACR_1603 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_809526.1 1514191 D 272622 CDS YP_809527.1 116512311 4434475 complement(1515626..1516318) 1 NC_008527.1 HAD superfamily hydrolase 1516318 4434475 LACR_1604 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_809527.1 1515626 R 272622 CDS YP_809528.1 116512312 4434476 complement(1516438..1517994) 1 NC_008527.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1517994 purH 4434476 purH Lactococcus lactis subsp. cremoris SK11 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_809528.1 1516438 R 272622 CDS YP_809529.1 116512313 4432259 complement(1518171..1518713) 1 NC_008527.1 hypoxanthine phosphoribosyltransferase 1518713 4432259 LACR_1606 Lactococcus lactis subsp. cremoris SK11 hypoxanthine phosphoribosyltransferase YP_809529.1 1518171 R 272622 CDS YP_809530.1 116512314 4432261 1520002..1520532 1 NC_008527.1 transcriptional regulator 1520532 4432261 LACR_1608 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809530.1 1520002 D 272622 CDS YP_809531.1 116512315 4432262 complement(1520584..1522173) 1 NC_008527.1 ABC transporter permease/ATP-binding protein 1522173 4432262 LACR_1609 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease/ATP-binding protein YP_809531.1 1520584 R 272622 CDS YP_809532.1 116512316 4432263 complement(1522364..1522912) 1 NC_008527.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 1522912 purN 4432263 purN Lactococcus lactis subsp. cremoris SK11 phosphoribosylglycinamide formyltransferase YP_809532.1 1522364 R 272622 CDS YP_809533.1 116512317 4432264 complement(1522941..1523957) 1 NC_008527.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1523957 4432264 LACR_1611 Lactococcus lactis subsp. cremoris SK11 phosphoribosylaminoimidazole synthetase YP_809533.1 1522941 R 272622 CDS YP_809534.1 116512318 4432265 complement(1524147..1526750) 1 NC_008527.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones 1526750 4432265 LACR_1612 Lactococcus lactis subsp. cremoris SK11 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones YP_809534.1 1524147 R 272622 CDS YP_809535.1 116512319 4432266 complement(1526938..1527264) 1 NC_008527.1 hypothetical protein 1527264 4432266 LACR_1613 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809535.1 1526938 R 272622 CDS YP_809536.1 116512320 4432267 complement(1527312..1527746) 1 NC_008527.1 surface antigen 1527746 4432267 LACR_1614 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_809536.1 1527312 R 272622 CDS YP_809537.1 116512321 4432268 1527957..1528349 1 NC_008527.1 hypothetical protein 1528349 4432268 LACR_1615 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809537.1 1527957 D 272622 CDS YP_809538.1 116512322 4432271 complement(1530070..1531590) 1 NC_008527.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1531590 4432271 LACR_1618 Lactococcus lactis subsp. cremoris SK11 amidophosphoribosyltransferase YP_809538.1 1530070 R 272622 CDS YP_809539.1 116512323 4432272 complement(1531575..1533794) 1 NC_008527.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1533794 4432272 LACR_1619 Lactococcus lactis subsp. cremoris SK11 phosphoribosylformylglycinamidine synthase II YP_809539.1 1531575 R 272622 CDS YP_809540.1 116512324 4432273 complement(1534011..1534691) 1 NC_008527.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 1534691 4432273 LACR_1620 Lactococcus lactis subsp. cremoris SK11 phosphoribosylformylglycinamidine synthase I YP_809540.1 1534011 R 272622 CDS YP_809541.1 116512325 4432274 complement(1534688..1534954) 1 NC_008527.1 phosphoribosylformylglycinamidine (FGAM) synthase, PurS component 1534954 4432274 LACR_1621 Lactococcus lactis subsp. cremoris SK11 phosphoribosylformylglycinamidine (FGAM) synthase, PurS component YP_809541.1 1534688 R 272622 CDS YP_809542.1 116512326 4432275 complement(1535009..1535719) 1 NC_008527.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1535719 4432275 LACR_1622 Lactococcus lactis subsp. cremoris SK11 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_809542.1 1535009 R 272622 CDS YP_809543.1 116512327 4432276 complement(1535858..1536265) 1 NC_008527.1 hypothetical protein 1536265 4432276 LACR_1623 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809543.1 1535858 R 272622 CDS YP_809544.1 116512328 4434103 complement(1536281..1536574) 1 NC_008527.1 hypothetical protein 1536574 4434103 LACR_1624 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809544.1 1536281 R 272622 CDS YP_809545.1 116512329 4434104 complement(1536587..1536901) 1 NC_008527.1 gamma-carboxymuconolactone decarboxylase subunit-like protein 1536901 4434104 LACR_1625 Lactococcus lactis subsp. cremoris SK11 gamma-carboxymuconolactone decarboxylase subunit-like protein YP_809545.1 1536587 R 272622 CDS YP_809546.1 116512330 4434105 complement(1536936..1537304) 1 NC_008527.1 hypothetical protein 1537304 4434105 LACR_1626 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809546.1 1536936 R 272622 CDS YP_809547.1 116512331 4434106 complement(1537321..1538088) 1 NC_008527.1 oxidoreductase 1538088 4434106 LACR_1627 Lactococcus lactis subsp. cremoris SK11 oxidoreductase YP_809547.1 1537321 R 272622 CDS YP_809548.1 116512332 4434107 complement(1538294..1539667) 1 NC_008527.1 major facilitator superfamily permease 1539667 4434107 LACR_1628 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_809548.1 1538294 R 272622 CDS YP_809549.1 116512333 4434108 complement(1539664..1540110) 1 NC_008527.1 transcriptional regulator 1540110 4434108 LACR_1629 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_809549.1 1539664 R 272622 CDS YP_809550.1 116512334 4434109 complement(1540375..1541247) 1 NC_008527.1 surface antigen 1541247 4434109 LACR_1630 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_809550.1 1540375 R 272622 CDS YP_809551.1 116512335 4434110 complement(1541521..1542360) 1 NC_008527.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1542360 thyA 4434110 thyA Lactococcus lactis subsp. cremoris SK11 thymidylate synthase YP_809551.1 1541521 R 272622 CDS YP_809552.1 116512336 4434112 complement(1544085..1545245) 1 NC_008527.1 AraC family transcriptional regulator 1545245 4434112 LACR_1633 Lactococcus lactis subsp. cremoris SK11 AraC family transcriptional regulator YP_809552.1 1544085 R 272622 CDS YP_809553.1 116512337 4434113 1545375..1545635 1 NC_008527.1 transposase 1545635 4434113 LACR_1634 Lactococcus lactis subsp. cremoris SK11 transposase YP_809553.1 1545375 D 272622 CDS YP_809554.1 116512338 4434114 1545632..1546486 1 NC_008527.1 transposase 1546486 4434114 LACR_1635 Lactococcus lactis subsp. cremoris SK11 transposase YP_809554.1 1545632 D 272622 CDS YP_809555.1 116512339 4434115 1546581..1547483 1 NC_008527.1 transcriptional regulator/sugar kinase 1547483 4434115 LACR_1636 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator/sugar kinase YP_809555.1 1546581 D 272622 CDS YP_809556.1 116512340 4434116 complement(1547633..1548997) 1 NC_008527.1 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase 1548997 4434116 LACR_1637 Lactococcus lactis subsp. cremoris SK11 Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase YP_809556.1 1547633 R 272622 CDS YP_809557.1 116512341 4434117 complement(1549050..1549499) 1 NC_008527.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 1549499 4434117 LACR_1638 Lactococcus lactis subsp. cremoris SK11 ribose-5-phosphate isomerase B YP_809557.1 1549050 R 272622 CDS YP_809558.1 116512342 4434118 complement(1549515..1550165) 1 NC_008527.1 ribulose-5-phosphate 3-epimerase 1550165 4434118 LACR_1639 Lactococcus lactis subsp. cremoris SK11 ribulose-5-phosphate 3-epimerase YP_809558.1 1549515 R 272622 CDS YP_809559.1 116512343 4434119 1550359..1551357 1 NC_008527.1 LacI family transcription regulator 1551357 4434119 LACR_1640 Lactococcus lactis subsp. cremoris SK11 LacI family transcription regulator YP_809559.1 1550359 D 272622 CDS YP_809560.1 116512344 4434494 complement(1551516..1552496) 1 NC_008527.1 threonine dehydrogenase related Zn-dependent dehydrogenase 1552496 4434494 LACR_1641 Lactococcus lactis subsp. cremoris SK11 threonine dehydrogenase related Zn-dependent dehydrogenase YP_809560.1 1551516 R 272622 CDS YP_809561.1 116512345 4434495 complement(1552609..1552878) 1 NC_008527.1 hypothetical protein 1552878 4434495 LACR_1642 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809561.1 1552609 R 272622 CDS YP_809562.1 116512346 4434496 complement(1552938..1553645) 1 NC_008527.1 hypothetical protein 1553645 4434496 LACR_1643 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809562.1 1552938 R 272622 CDS YP_809563.1 116512347 4434497 complement(1553719..1554654) 1 NC_008527.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 1554654 4434497 LACR_1644 Lactococcus lactis subsp. cremoris SK11 dihydroorotate dehydrogenase 1A YP_809563.1 1553719 R 272622 CDS YP_809564.1 116512348 4434498 1554795..1555346 1 NC_008527.1 peptide methionine sulfoxide reductase 1555346 4434498 LACR_1645 Lactococcus lactis subsp. cremoris SK11 peptide methionine sulfoxide reductase YP_809564.1 1554795 D 272622 CDS YP_809565.1 116512349 4434499 complement(1555357..1556331) 1 NC_008527.1 dehydrogenase related protein 1556331 4434499 LACR_1646 Lactococcus lactis subsp. cremoris SK11 dehydrogenase related protein YP_809565.1 1555357 R 272622 CDS YP_809566.1 116512350 4434500 complement(1556355..1556537) 1 NC_008527.1 hypothetical protein 1556537 4434500 LACR_1647 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809566.1 1556355 R 272622 CDS YP_809567.1 116512351 4434501 complement(1556544..1558415) 1 NC_008527.1 ABC transporter ATPase 1558415 4434501 LACR_1648 Lactococcus lactis subsp. cremoris SK11 ABC transporter ATPase YP_809567.1 1556544 R 272622 CDS YP_809568.1 116512352 4434502 complement(1558563..1559516) 1 NC_008527.1 fhu operon transcription regulator 1559516 4434502 LACR_1649 Lactococcus lactis subsp. cremoris SK11 fhu operon transcription regulator YP_809568.1 1558563 R 272622 CDS YP_809569.1 116512353 4434503 complement(1559600..1560679) 1 NC_008527.1 glycerol dehydrogenase 1560679 4434503 LACR_1650 Lactococcus lactis subsp. cremoris SK11 glycerol dehydrogenase YP_809569.1 1559600 R 272622 CDS YP_809570.1 116512354 4434504 complement(1560785..1561195) 1 NC_008527.1 hypothetical protein 1561195 4434504 LACR_1651 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809570.1 1560785 R 272622 CDS YP_809571.1 116512355 4434505 complement(1561414..1562838) 1 NC_008527.1 dipeptidase A 1562838 4434505 LACR_1652 Lactococcus lactis subsp. cremoris SK11 dipeptidase A YP_809571.1 1561414 R 272622 CDS YP_809572.1 116512356 4434506 complement(1562961..1564169) 1 NC_008527.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1564169 4434506 LACR_1653 Lactococcus lactis subsp. cremoris SK11 tRNA CCA-pyrophosphorylase YP_809572.1 1562961 R 272622 CDS YP_809573.1 116512357 4434507 complement(1564370..1564912) 1 NC_008527.1 acetyltransferase 1564912 4434507 LACR_1654 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_809573.1 1564370 R 272622 CDS YP_809574.1 116512358 4434508 complement(1564978..1565760) 1 NC_008527.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1565760 4434508 LACR_1655 Lactococcus lactis subsp. cremoris SK11 dihydrodipicolinate reductase YP_809574.1 1564978 R 272622 CDS YP_809575.1 116512359 4434509 complement(1565890..1566735) 1 NC_008527.1 hypothetical protein 1566735 4434509 LACR_1656 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809575.1 1565890 R 272622 CDS YP_809576.1 116512360 4434510 complement(1566752..1567144) 1 NC_008527.1 hypothetical protein 1567144 4434510 LACR_1657 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809576.1 1566752 R 272622 CDS YP_809577.1 116512361 4434511 complement(1567270..1568025) 1 NC_008527.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1568025 trmD 4434511 trmD Lactococcus lactis subsp. cremoris SK11 tRNA (guanine-N(1)-)-methyltransferase YP_809577.1 1567270 R 272622 CDS YP_809578.1 116512362 4433176 complement(1568018..1568533) 1 NC_008527.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1568533 rimM 4433176 rimM Lactococcus lactis subsp. cremoris SK11 16S rRNA-processing protein RimM YP_809578.1 1568018 R 272622 CDS YP_809579.1 116512363 4433177 complement(1568718..1569563) 1 NC_008527.1 lysophospholipase 1569563 4433177 LACR_1660 Lactococcus lactis subsp. cremoris SK11 lysophospholipase YP_809579.1 1568718 R 272622 CDS YP_809580.1 116512364 4433178 complement(1569589..1570545) 1 NC_008527.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1570545 hemH 4433178 hemH Lactococcus lactis subsp. cremoris SK11 ferrochelatase YP_809580.1 1569589 R 272622 CDS YP_809581.1 116512365 4433179 complement(1570745..1570984) 1 NC_008527.1 RNA-binding protein 1570984 4433179 LACR_1662 Lactococcus lactis subsp. cremoris SK11 RNA-binding protein YP_809581.1 1570745 R 272622 CDS YP_809582.1 116512366 4433180 complement(1571080..1571352) 1 NC_008527.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1571352 rpsP 4433180 rpsP Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S16 YP_809582.1 1571080 R 272622 CDS YP_809583.1 116512367 4433181 complement(1571437..1572669) 1 NC_008527.1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1572669 4433181 LACR_1664 Lactococcus lactis subsp. cremoris SK11 3-hydroxy-3-methylglutaryl-coenzyme A reductase YP_809583.1 1571437 R 272622 CDS YP_809584.1 116512368 4433182 complement(1572717..1573856) 1 NC_008527.1 Acetyl-CoA acetyltransferase 1573856 4433182 LACR_1665 Lactococcus lactis subsp. cremoris SK11 Acetyl-CoA acetyltransferase YP_809584.1 1572717 R 272622 CDS YP_809585.1 116512369 4433183 1574161..1575315 1 NC_008527.1 hydroxymethylglutaryl-CoA synthase 1575315 4433183 LACR_1666 Lactococcus lactis subsp. cremoris SK11 hydroxymethylglutaryl-CoA synthase YP_809585.1 1574161 D 272622 CDS YP_809586.1 116512370 4433184 complement(1575376..1576083) 1 NC_008527.1 glucosamine-6-phosphate isomerase 1576083 4433184 LACR_1667 Lactococcus lactis subsp. cremoris SK11 glucosamine-6-phosphate isomerase YP_809586.1 1575376 R 272622 CDS YP_809587.1 116512371 4433185 complement(1576257..1577210) 1 NC_008527.1 alpha/beta fold family hydrolase 1577210 4433185 LACR_1668 Lactococcus lactis subsp. cremoris SK11 alpha/beta fold family hydrolase YP_809587.1 1576257 R 272622 CDS YP_809588.1 116512372 4433186 1577805..1578362 1 NC_008527.1 transposase 1578362 4433186 LACR_1669 Lactococcus lactis subsp. cremoris SK11 transposase YP_809588.1 1577805 D 272622 CDS YP_809589.1 116512373 4433187 1578448..1579179 1 NC_008527.1 transposase 1579179 4433187 LACR_1670 Lactococcus lactis subsp. cremoris SK11 transposase YP_809589.1 1578448 D 272622 CDS YP_809590.1 116512374 4433188 complement(1579236..1580075) 1 NC_008527.1 transposase 1580075 4433188 LACR_1671 Lactococcus lactis subsp. cremoris SK11 transposase YP_809590.1 1579236 R 272622 CDS YP_809591.1 116512375 4433189 complement(1580093..1580383) 1 NC_008527.1 transposase 1580383 4433189 LACR_1672 Lactococcus lactis subsp. cremoris SK11 transposase YP_809591.1 1580093 R 272622 CDS YP_809592.1 116512376 4433190 complement(1580618..1580914) 1 NC_008527.1 hypothetical protein 1580914 4433190 LACR_1673 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809592.1 1580618 R 272622 CDS YP_809593.1 116512377 4433191 complement(1581047..1581268) 1 NC_008527.1 hypothetical protein 1581268 4433191 LACR_1674 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809593.1 1581047 R 272622 CDS YP_809594.1 116512378 4433192 complement(1581361..1581657) 1 NC_008527.1 hypothetical protein 1581657 4433192 LACR_1675 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809594.1 1581361 R 272622 CDS YP_809595.1 116512379 4432106 1581715..1581975 1 NC_008527.1 transposase 1581975 4432106 LACR_1676 Lactococcus lactis subsp. cremoris SK11 transposase YP_809595.1 1581715 D 272622 CDS YP_809596.1 116512380 4432107 1581972..1582826 1 NC_008527.1 transposase 1582826 4432107 LACR_1677 Lactococcus lactis subsp. cremoris SK11 transposase YP_809596.1 1581972 D 272622 CDS YP_809597.1 116512381 4432108 1583032..1583979 1 NC_008527.1 hypothetical protein 1583979 4432108 LACR_1678 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809597.1 1583032 D 272622 CDS YP_809598.1 116512382 4432109 1584097..1585215 1 NC_008527.1 integrase 1585215 4432109 LACR_1679 Lactococcus lactis subsp. cremoris SK11 integrase YP_809598.1 1584097 D 272622 CDS YP_809599.1 116512383 4432110 1585351..1586397 1 NC_008527.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1586397 queA 4432110 queA Lactococcus lactis subsp. cremoris SK11 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_809599.1 1585351 D 272622 CDS YP_809600.1 116512384 4432112 complement(1587046..1588047) 1 NC_008527.1 cell surface protein 1588047 4432112 LACR_1682 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_809600.1 1587046 R 272622 CDS YP_809601.1 116512385 4432113 complement(1588169..1590232) 1 NC_008527.1 hypothetical protein 1590232 4432113 LACR_1683 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809601.1 1588169 R 272622 CDS YP_809602.1 116512386 4432114 1590297..1590389 1 NC_008527.1 hypothetical protein 1590389 4432114 LACR_1684 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809602.1 1590297 D 272622 CDS YP_809603.1 116512387 4432115 1590970..1592769 1 NC_008527.1 retron-type reverse transcriptase 1592769 4432115 LACR_1685 Lactococcus lactis subsp. cremoris SK11 retron-type reverse transcriptase YP_809603.1 1590970 D 272622 CDS YP_809604.1 116512388 4432116 complement(1592602..1595559) 1 NC_008527.1 hypothetical protein 1595559 4432116 LACR_1686 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809604.1 1592602 R 272622 CDS YP_809605.1 116512389 4432117 complement(1595596..1596351) 1 NC_008527.1 cell surface protein 1596351 4432117 LACR_1687 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_809605.1 1595596 R 272622 CDS YP_809606.1 116512390 4432118 complement(1596389..1597147) 1 NC_008527.1 cell surface protein 1597147 4432118 LACR_1688 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_809606.1 1596389 R 272622 CDS YP_809607.1 116512391 4432119 complement(1597185..1597976) 1 NC_008527.1 cell surface protein 1597976 4432119 LACR_1689 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_809607.1 1597185 R 272622 CDS YP_809608.1 116512392 4432120 complement(1598005..1598850) 1 NC_008527.1 cell surface protein 1598850 4432120 LACR_1690 Lactococcus lactis subsp. cremoris SK11 cell surface protein YP_809608.1 1598005 R 272622 CDS YP_809609.1 116512393 4432121 complement(1598909..1599208) 1 NC_008527.1 hypothetical protein 1599208 4432121 LACR_1691 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809609.1 1598909 R 272622 CDS YP_809610.1 116512394 4432122 1599576..1600178 1 NC_008527.1 hypothetical protein 1600178 4432122 LACR_1692 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809610.1 1599576 D 272622 CDS YP_809611.1 116512395 4432123 complement(1600227..1600397) 1 NC_008527.1 hypothetical protein 1600397 4432123 LACR_1693 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809611.1 1600227 R 272622 CDS YP_809612.1 116512396 4432534 complement(1600425..1601738) 1 NC_008527.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1601738 obgE 4432534 obgE Lactococcus lactis subsp. cremoris SK11 GTPase ObgE YP_809612.1 1600425 R 272622 CDS YP_809613.1 116512397 4432535 complement(1601888..1603054) 1 NC_008527.1 cell division protein FtsQ 1603054 4432535 LACR_1695 Lactococcus lactis subsp. cremoris SK11 cell division protein FtsQ YP_809613.1 1601888 R 272622 CDS YP_809614.1 116512398 4432536 complement(1603055..1604128) 1 NC_008527.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1604128 murG 4432536 murG Lactococcus lactis subsp. cremoris SK11 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_809614.1 1603055 R 272622 CDS YP_809615.1 116512399 4432537 complement(1604371..1605720) 1 NC_008527.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1605720 murD 4432537 murD Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_809615.1 1604371 R 272622 CDS YP_809616.1 116512400 4432538 complement(1605889..1606230) 1 NC_008527.1 nitrogen regulatory protein P-II 1606230 4432538 LACR_1698 Lactococcus lactis subsp. cremoris SK11 nitrogen regulatory protein P-II YP_809616.1 1605889 R 272622 CDS YP_809617.1 116512401 4432539 complement(1606312..1607553) 1 NC_008527.1 ammonia permease 1607553 4432539 LACR_1699 Lactococcus lactis subsp. cremoris SK11 ammonia permease YP_809617.1 1606312 R 272622 CDS YP_809618.1 116512402 4432540 complement(1607739..1609028) 1 NC_008527.1 Signal transduction histidine kinase 1609028 4432540 LACR_1700 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_809618.1 1607739 R 272622 CDS YP_809619.1 116512403 4432541 complement(1609217..1609909) 1 NC_008527.1 DNA-binding response regulator 1609909 4432541 LACR_1701 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_809619.1 1609217 R 272622 CDS YP_809620.1 116512404 4432542 complement(1610066..1610596) 1 NC_008527.1 hypothetical protein 1610596 4432542 LACR_1702 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809620.1 1610066 R 272622 CDS YP_809621.1 116512405 4432543 complement(1610729..1610974) 1 NC_008527.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1610974 rpmE2 4432543 rpmE2 Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L31 YP_809621.1 1610729 R 272622 CDS YP_809622.1 116512406 4432544 complement(1611298..1611660) 1 NC_008527.1 hypothetical protein 1611660 4432544 LACR_1704 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809622.1 1611298 R 272622 CDS YP_809623.1 116512407 4432545 complement(1611897..1612808) 1 NC_008527.1 surface antigen 1612808 4432545 LACR_1705 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_809623.1 1611897 R 272622 CDS YP_809624.1 116512408 4432546 complement(1612901..1613719) 1 NC_008527.1 phosphohydrolase 1613719 4432546 LACR_1706 Lactococcus lactis subsp. cremoris SK11 phosphohydrolase YP_809624.1 1612901 R 272622 CDS YP_809625.1 116512409 4432547 complement(1613849..1614253) 1 NC_008527.1 arsenate reductase 1614253 4432547 LACR_1707 Lactococcus lactis subsp. cremoris SK11 arsenate reductase YP_809625.1 1613849 R 272622 CDS YP_809626.1 116512410 4432548 1614690..1615460 1 NC_008527.1 surface antigen 1615460 4432548 LACR_1708 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_809626.1 1614690 D 272622 CDS YP_809627.1 116512411 4432549 complement(1615621..1616694) 1 NC_008527.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1616694 4432549 LACR_1709 Lactococcus lactis subsp. cremoris SK11 carbamoyl phosphate synthase small subunit YP_809627.1 1615621 R 272622 CDS YP_809628.1 116512412 4432550 complement(1616782..1617714) 1 NC_008527.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 1617714 pyrB 4432550 pyrB Lactococcus lactis subsp. cremoris SK11 aspartate carbamoyltransferase catalytic subunit YP_809628.1 1616782 R 272622 CDS YP_809629.1 116512413 4434616 complement(1617963..1619255) 1 NC_008527.1 xanthine/uracil permease 1619255 4434616 LACR_1711 Lactococcus lactis subsp. cremoris SK11 xanthine/uracil permease YP_809629.1 1617963 R 272622 CDS YP_809630.1 116512414 4434617 complement(1619355..1619876) 1 NC_008527.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 1619876 4434617 LACR_1712 Lactococcus lactis subsp. cremoris SK11 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_809630.1 1619355 R 272622 CDS YP_809631.1 116512415 4434618 complement(1620152..1620850) 1 NC_008527.1 hypothetical protein 1620850 4434618 LACR_1713 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809631.1 1620152 R 272622 CDS YP_809632.1 116512416 4434619 1620955..1621254 1 NC_008527.1 ArsR family transcriptional regulator 1621254 4434619 LACR_1714 Lactococcus lactis subsp. cremoris SK11 ArsR family transcriptional regulator YP_809632.1 1620955 D 272622 CDS YP_809633.1 116512417 4434620 1621244..1622161 1 NC_008527.1 cation transport protein 1622161 4434620 LACR_1715 Lactococcus lactis subsp. cremoris SK11 cation transport protein YP_809633.1 1621244 D 272622 CDS YP_809634.1 116512418 4434621 complement(1622399..1623640) 1 NC_008527.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1623640 proA 4434621 proA Lactococcus lactis subsp. cremoris SK11 gamma-glutamyl phosphate reductase YP_809634.1 1622399 R 272622 CDS YP_809635.1 116512419 4434622 complement(1623751..1624563) 1 NC_008527.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1624563 4434622 LACR_1717 Lactococcus lactis subsp. cremoris SK11 gamma-glutamyl kinase YP_809635.1 1623751 R 272622 CDS YP_809636.1 116512420 4434623 complement(1624718..1626175) 1 NC_008527.1 hypothetical protein 1626175 4434623 LACR_1718 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809636.1 1624718 R 272622 CDS YP_809637.1 116512421 4434624 complement(1626172..1626414) 1 NC_008527.1 hypothetical protein 1626414 4434624 LACR_1719 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809637.1 1626172 R 272622 CDS YP_809638.1 116512422 4434625 complement(1626530..1626856) 1 NC_008527.1 hypothetical protein 1626856 4434625 LACR_1720 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809638.1 1626530 R 272622 CDS YP_809639.1 116512423 4434626 complement(1626843..1627550) 1 NC_008527.1 branched-chain amino acid permease (azaleucine resistance) 1627550 4434626 LACR_1721 Lactococcus lactis subsp. cremoris SK11 branched-chain amino acid permease (azaleucine resistance) YP_809639.1 1626843 R 272622 CDS YP_809640.1 116512424 4434627 1627745..1628317 1 NC_008527.1 dinucleotide-binding protein 1628317 4434627 LACR_1722 Lactococcus lactis subsp. cremoris SK11 dinucleotide-binding protein YP_809640.1 1627745 D 272622 CDS YP_809641.1 116512425 4434628 1628465..1629355 1 NC_008527.1 transposase 1629355 4434628 LACR_1723 Lactococcus lactis subsp. cremoris SK11 transposase YP_809641.1 1628465 D 272622 CDS YP_809642.1 116512426 4434629 1629409..1630047 1 NC_008527.1 spermidine acetyltransferase 1630047 4434629 LACR_1724 Lactococcus lactis subsp. cremoris SK11 spermidine acetyltransferase YP_809642.1 1629409 D 272622 CDS YP_809643.1 116512427 4434630 complement(1629986..1631542) 1 NC_008527.1 signal recognition particle protein 1631542 4434630 LACR_1725 Lactococcus lactis subsp. cremoris SK11 signal recognition particle protein YP_809643.1 1629986 R 272622 CDS YP_809644.1 116512428 4434631 complement(1631621..1634674) 1 NC_008527.1 subtilisin-like serine protease 1634674 4434631 LACR_1726 Lactococcus lactis subsp. cremoris SK11 subtilisin-like serine protease YP_809644.1 1631621 R 272622 CDS YP_809645.1 116512429 4434632 complement(1634723..1636435) 1 NC_008527.1 metallo-beta-lactamase superfamily hydrolase 1636435 4434632 LACR_1727 Lactococcus lactis subsp. cremoris SK11 metallo-beta-lactamase superfamily hydrolase YP_809645.1 1634723 R 272622 CDS YP_809646.1 116512430 4434633 1636785..1637456 1 NC_008527.1 Mg2+ transporter 1637456 4434633 LACR_1728 Lactococcus lactis subsp. cremoris SK11 Mg2+ transporter YP_809646.1 1636785 D 272622 CDS YP_809647.1 116512431 4433511 complement(1637496..1638389) 1 NC_008527.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1638389 4433511 LACR_1729 Lactococcus lactis subsp. cremoris SK11 dihydrodipicolinate synthase YP_809647.1 1637496 R 272622 CDS YP_809650.1 116512432 4433512 complement(1638718..1639173) 1 NC_008527.1 ADP-ribose pyrophosphatase 1639173 4433512 LACR_1730 Lactococcus lactis subsp. cremoris SK11 ADP-ribose pyrophosphatase YP_809650.1 1638718 R 272622 CDS YP_809652.1 116512433 4433513 complement(1639183..1640259) 1 NC_008527.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1640259 4433513 LACR_1731 Lactococcus lactis subsp. cremoris SK11 aspartate-semialdehyde dehydrogenase YP_809652.1 1639183 R 272622 CDS YP_809654.1 116512434 4433514 complement(1640355..1641218) 1 NC_008527.1 glycerol uptake facilitator related permease (major Intrinsic protein family) 1641218 4433514 LACR_1732 Lactococcus lactis subsp. cremoris SK11 glycerol uptake facilitator related permease (major Intrinsic protein family) YP_809654.1 1640355 R 272622 CDS YP_809656.1 116512435 4433515 complement(1641567..1641818) 1 NC_008527.1 hypothetical protein 1641818 4433515 LACR_1733 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809656.1 1641567 R 272622 CDS YP_809659.1 116512436 4433516 complement(1641986..1643962) 1 NC_008527.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1643962 4433516 LACR_1734 Lactococcus lactis subsp. cremoris SK11 transketolase YP_809659.1 1641986 R 272622 CDS YP_809661.1 116512437 4433517 complement(1644130..1645530) 1 NC_008527.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1645530 ulaA 4433517 ulaA Lactococcus lactis subsp. cremoris SK11 PTS system ascorbate-specific transporter subunit IIC YP_809661.1 1644130 R 272622 CDS YP_809663.1 116512438 4433518 complement(1645583..1645882) 1 NC_008527.1 phosphotransferase system, galactitol-specific IIB component 1645882 4433518 LACR_1736 Lactococcus lactis subsp. cremoris SK11 phosphotransferase system, galactitol-specific IIB component YP_809663.1 1645583 R 272622 CDS YP_809665.1 116512439 4433519 complement(1645884..1646339) 1 NC_008527.1 phosphotransferase system mannitol/fructose-specific IIA domain-containing protein 1646339 4433519 LACR_1737 Lactococcus lactis subsp. cremoris SK11 phosphotransferase system mannitol/fructose-specific IIA domain-containing protein YP_809665.1 1645884 R 272622 CDS YP_809668.1 116512440 4433520 complement(1646471..1647361) 1 NC_008527.1 transposase 1647361 4433520 LACR_1738 Lactococcus lactis subsp. cremoris SK11 transposase YP_809668.1 1646471 R 272622 CDS YP_809670.1 116512441 4433521 complement(1647418..1648830) 1 NC_008527.1 transcriptional antiterminator 1648830 4433521 LACR_1739 Lactococcus lactis subsp. cremoris SK11 transcriptional antiterminator YP_809670.1 1647418 R 272622 CDS YP_809673.1 116512442 4433522 complement(1649005..1649646) 1 NC_008527.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1649646 4433522 LACR_1740 Lactococcus lactis subsp. cremoris SK11 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_809673.1 1649005 R 272622 CDS YP_809675.1 116512443 4433523 complement(1649659..1650471) 1 NC_008527.1 2-dehydro-3-deoxygluconokinase 1650471 4433523 LACR_1741 Lactococcus lactis subsp. cremoris SK11 2-dehydro-3-deoxygluconokinase YP_809675.1 1649659 R 272622 CDS YP_809678.1 116512444 4433524 complement(1650597..1652015) 1 NC_008527.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 1652015 4433524 LACR_1742 Lactococcus lactis subsp. cremoris SK11 glucuronate isomerase YP_809678.1 1650597 R 272622 CDS YP_809680.1 116512445 4433525 complement(1652028..1652909) 1 NC_008527.1 hypothetical protein 1652909 4433525 LACR_1743 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809680.1 1652028 R 272622 CDS YP_809682.1 116512446 4433526 complement(1652969..1654495) 1 NC_008527.1 Na-galactoside symporter 1654495 4433526 LACR_1744 Lactococcus lactis subsp. cremoris SK11 Na-galactoside symporter YP_809682.1 1652969 R 272622 CDS YP_809685.1 116512447 4433527 complement(1654681..1655745) 1 NC_008527.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 1655745 4433527 LACR_1745 Lactococcus lactis subsp. cremoris SK11 mannonate dehydratase YP_809685.1 1654681 R 272622 CDS YP_809688.1 116512448 4432645 complement(1655914..1657548) 1 NC_008527.1 fructuronate reductase 1657548 4432645 LACR_1746 Lactococcus lactis subsp. cremoris SK11 fructuronate reductase YP_809688.1 1655914 R 272622 CDS YP_809690.1 116512449 4432646 1657932..1658612 1 NC_008527.1 GntR family transcriptional regulator 1658612 4432646 LACR_1747 Lactococcus lactis subsp. cremoris SK11 GntR family transcriptional regulator YP_809690.1 1657932 D 272622 CDS YP_809692.1 116512450 4432647 complement(1658677..1660107) 1 NC_008527.1 major facilitator superfamily permease 1660107 4432647 LACR_1748 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_809692.1 1658677 R 272622 CDS YP_809695.1 116512451 4432648 complement(1660466..1660771) 1 NC_008527.1 hypothetical protein 1660771 4432648 LACR_1749 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809695.1 1660466 R 272622 CDS YP_809699.1 116512452 4432649 complement(1660776..1661000) 1 NC_008527.1 hypothetical protein 1661000 4432649 LACR_1750 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809699.1 1660776 R 272622 CDS YP_809702.1 116512453 4432650 1661215..1662093 1 NC_008527.1 transposase 1662093 4432650 LACR_1751 Lactococcus lactis subsp. cremoris SK11 transposase YP_809702.1 1661215 D 272622 CDS YP_809703.1 116512454 4432651 complement(1662075..1662275) 1 NC_008527.1 hypothetical protein 1662275 4432651 LACR_1752 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_809703.1 1662075 R 272622 CDS YP_811362.1 116512455 4432653 complement(1663287..1664633) 1 NC_008527.1 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) 1664633 4432653 LACR_1754 Lactococcus lactis subsp. cremoris SK11 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) YP_811362.1 1663287 R 272622 CDS YP_811363.1 116512456 4432654 complement(1664630..1664896) 1 NC_008527.1 hypothetical protein 1664896 4432654 LACR_1755 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811363.1 1664630 R 272622 CDS YP_811364.1 116512457 4432655 complement(1664921..1666972) 1 NC_008527.1 hypothetical protein 1666972 4432655 LACR_1756 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811364.1 1664921 R 272622 CDS YP_811365.1 116512458 4432656 complement(1666985..1667209) 1 NC_008527.1 hypothetical protein 1667209 4432656 LACR_1757 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811365.1 1666985 R 272622 CDS YP_811366.1 116512459 4432657 complement(1667222..1667737) 1 NC_008527.1 hypothetical protein 1667737 4432657 LACR_1758 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811366.1 1667222 R 272622 CDS YP_811367.1 116512460 4432658 complement(1667756..1669099) 1 NC_008527.1 hypothetical protein 1669099 4432658 LACR_1759 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811367.1 1667756 R 272622 CDS YP_811368.1 116512461 4432660 complement(1670082..1672871) 1 NC_008527.1 hypothetical protein 1672871 4432660 LACR_1761 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811368.1 1670082 R 272622 CDS YP_811369.1 116512462 4432661 complement(1672871..1673632) 1 NC_008527.1 hypothetical protein 1673632 4432661 LACR_1762 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811369.1 1672871 R 272622 CDS YP_811370.1 116512463 4433494 complement(1673646..1675859) 1 NC_008527.1 minor tail protein gp26-like protein 1675859 4433494 LACR_1763 Lactococcus lactis subsp. cremoris SK11 minor tail protein gp26-like protein YP_811370.1 1673646 R 272622 CDS YP_811371.1 116512464 4433495 complement(1675875..1676144) 1 NC_008527.1 hypothetical protein 1676144 4433495 LACR_1764 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811371.1 1675875 R 272622 CDS YP_811372.1 116512465 4433496 complement(1676228..1676578) 1 NC_008527.1 hypothetical protein 1676578 4433496 LACR_1765 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811372.1 1676228 R 272622 CDS YP_811373.1 116512466 4433497 complement(1676694..1677203) 1 NC_008527.1 hypothetical protein 1677203 4433497 LACR_1766 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811373.1 1676694 R 272622 CDS YP_811374.1 116512467 4433498 complement(1677214..1677603) 1 NC_008527.1 hypothetical protein 1677603 4433498 LACR_1767 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811374.1 1677214 R 272622 CDS YP_811375.1 116512468 4433499 complement(1677600..1677938) 1 NC_008527.1 hypothetical protein 1677938 4433499 LACR_1768 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811375.1 1677600 R 272622 CDS YP_811376.1 116512469 4433500 complement(1677935..1678246) 1 NC_008527.1 hypothetical protein 1678246 4433500 LACR_1769 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811376.1 1677935 R 272622 CDS YP_811377.1 116512470 4433501 complement(1678243..1678575) 1 NC_008527.1 hypothetical protein 1678575 4433501 LACR_1770 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811377.1 1678243 R 272622 CDS YP_811378.1 116512471 4433502 complement(1678559..1678759) 1 NC_008527.1 hypothetical protein 1678759 4433502 LACR_1771 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811378.1 1678559 R 272622 CDS YP_811379.1 116512472 4433503 complement(1678759..1679535) 1 NC_008527.1 hypothetical protein 1679535 4433503 LACR_1772 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811379.1 1678759 R 272622 CDS YP_811380.1 116512473 4433504 complement(1679581..1680249) 1 NC_008527.1 hypothetical protein 1680249 4433504 LACR_1773 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811380.1 1679581 R 272622 CDS YP_811381.1 116512474 4433505 1680434..1680781 1 NC_008527.1 hypothetical protein 1680781 4433505 LACR_1774 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811381.1 1680434 D 272622 CDS YP_811382.1 116512475 4433506 complement(1680741..1681082) 1 NC_008527.1 hypothetical protein 1681082 4433506 LACR_1775 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811382.1 1680741 R 272622 CDS YP_811383.1 116512476 4433507 complement(1681079..1682128) 1 NC_008527.1 Phage Mu protein F like protein 1682128 4433507 LACR_1776 Lactococcus lactis subsp. cremoris SK11 Phage Mu protein F like protein YP_811383.1 1681079 R 272622 CDS YP_811384.1 116512477 4433508 complement(1682132..1683508) 1 NC_008527.1 Phage portal protein, SPP1 Gp6-like 1683508 4433508 LACR_1777 Lactococcus lactis subsp. cremoris SK11 Phage portal protein, SPP1 Gp6-like YP_811384.1 1682132 R 272622 CDS YP_811385.1 116512478 4433509 complement(1683523..1684911) 1 NC_008527.1 hypothetical protein 1684911 4433509 LACR_1778 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811385.1 1683523 R 272622 CDS YP_811386.1 116512479 4433510 complement(1684904..1685314) 1 NC_008527.1 Phage terminase, small subunit 1685314 4433510 LACR_1779 Lactococcus lactis subsp. cremoris SK11 Phage terminase, small subunit YP_811386.1 1684904 R 272622 CDS YP_811387.1 116512480 4434303 complement(1685623..1686045) 1 NC_008527.1 hypothetical protein 1686045 4434303 LACR_1780 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811387.1 1685623 R 272622 CDS YP_811388.1 116512481 4434304 complement(1686123..1686329) 1 NC_008527.1 hypothetical protein 1686329 4434304 LACR_1781 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811388.1 1686123 R 272622 CDS YP_811389.1 116512482 4434305 complement(1686458..1686751) 1 NC_008527.1 hypothetical protein 1686751 4434305 LACR_1782 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811389.1 1686458 R 272622 CDS YP_811390.1 116512483 4434306 complement(1686882..1687085) 1 NC_008527.1 hypothetical protein 1687085 4434306 LACR_1783 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811390.1 1686882 R 272622 CDS YP_811391.1 116512484 4434307 complement(1687082..1687312) 1 NC_008527.1 hypothetical protein 1687312 4434307 LACR_1784 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811391.1 1687082 R 272622 CDS YP_811392.1 116512485 4434308 complement(1687365..1687784) 1 NC_008527.1 dUTPase 1687784 4434308 LACR_1785 Lactococcus lactis subsp. cremoris SK11 dUTPase YP_811392.1 1687365 R 272622 CDS YP_811393.1 116512486 4434309 complement(1687781..1688092) 1 NC_008527.1 hypothetical protein 1688092 4434309 LACR_1786 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811393.1 1687781 R 272622 CDS YP_811394.1 116512487 4434310 complement(1688089..1688703) 1 NC_008527.1 hypothetical protein 1688703 4434310 LACR_1787 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811394.1 1688089 R 272622 CDS YP_811395.1 116512488 4434311 complement(1688696..1688902) 1 NC_008527.1 hypothetical protein 1688902 4434311 LACR_1788 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811395.1 1688696 R 272622 CDS YP_811396.1 116512489 4434312 complement(1688903..1689163) 1 NC_008527.1 hypothetical protein 1689163 4434312 LACR_1789 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811396.1 1688903 R 272622 CDS YP_811397.1 116512490 4434313 complement(1689234..1689743) 1 NC_008527.1 hypothetical protein 1689743 4434313 LACR_1790 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811397.1 1689234 R 272622 CDS YP_811398.1 116512491 4434314 complement(1689733..1689912) 1 NC_008527.1 hypothetical protein 1689912 4434314 LACR_1791 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811398.1 1689733 R 272622 CDS YP_811399.1 116512492 4434315 complement(1690024..1690272) 1 NC_008527.1 hypothetical protein 1690272 4434315 LACR_1792 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811399.1 1690024 R 272622 CDS YP_811400.1 116512493 4434316 complement(1690276..1690665) 1 NC_008527.1 Holliday junction resolvase 1690665 4434316 LACR_1793 Lactococcus lactis subsp. cremoris SK11 Holliday junction resolvase YP_811400.1 1690276 R 272622 CDS YP_811401.1 116512494 4434317 complement(1690662..1691387) 1 NC_008527.1 hypothetical protein 1691387 4434317 LACR_1794 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811401.1 1690662 R 272622 CDS YP_811402.1 116512495 4434318 complement(1691387..1691602) 1 NC_008527.1 hypothetical protein 1691602 4434318 LACR_1795 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811402.1 1691387 R 272622 CDS YP_811403.1 116512496 4434319 1691808..1692068 1 NC_008527.1 transposase 1692068 4434319 LACR_1796 Lactococcus lactis subsp. cremoris SK11 transposase YP_811403.1 1691808 D 272622 CDS YP_811404.1 116512497 4434320 1692065..1692919 1 NC_008527.1 transposase 1692919 4434320 LACR_1797 Lactococcus lactis subsp. cremoris SK11 transposase YP_811404.1 1692065 D 272622 CDS YP_811405.1 116512498 4432431 complement(1693189..1694163) 1 NC_008527.1 ABC-type sugar transport system, periplasmic component 1694163 4432431 LACR_1798 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, periplasmic component YP_811405.1 1693189 R 272622 CDS YP_811406.1 116512499 4432433 complement(1695121..1696599) 1 NC_008527.1 ABC-type sugar transport system, ATPase component 1696599 4432433 LACR_1800 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, ATPase component YP_811406.1 1695121 R 272622 CDS YP_811407.1 116512500 4432434 complement(1696618..1697016) 1 NC_008527.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 1697016 4432434 LACR_1801 Lactococcus lactis subsp. cremoris SK11 D-ribose pyranase YP_811407.1 1696618 R 272622 CDS YP_811408.1 116512501 4432435 complement(1697021..1697941) 1 NC_008527.1 ribokinase family sugar kinase 1697941 4432435 LACR_1802 Lactococcus lactis subsp. cremoris SK11 ribokinase family sugar kinase YP_811408.1 1697021 R 272622 CDS YP_811409.1 116512502 4432436 complement(1697952..1698935) 1 NC_008527.1 LacI family transcription regulator 1698935 4432436 LACR_1803 Lactococcus lactis subsp. cremoris SK11 LacI family transcription regulator YP_811409.1 1697952 R 272622 CDS YP_811410.1 116512503 4432437 complement(1699070..1700365) 1 NC_008527.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1700365 4432437 LACR_1804 Lactococcus lactis subsp. cremoris SK11 adenylosuccinate lyase YP_811410.1 1699070 R 272622 CDS YP_811411.1 116512504 4432438 complement(1700580..1701269) 1 NC_008527.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1701269 aroD 4432438 aroD Lactococcus lactis subsp. cremoris SK11 3-dehydroquinate dehydratase YP_811411.1 1700580 R 272622 CDS YP_811412.1 116512505 4432440 complement(1701542..1701745) 1 NC_008527.1 hypothetical protein 1701745 4432440 LACR_1807 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811412.1 1701542 R 272622 CDS YP_811413.1 116512506 4432441 complement(1701987..1702301) 1 NC_008527.1 Thiol-disulfide isomerase or thioredoxin 1702301 4432441 LACR_1808 Lactococcus lactis subsp. cremoris SK11 Thiol-disulfide isomerase or thioredoxin YP_811413.1 1701987 R 272622 CDS YP_811414.1 116512507 4432442 complement(1702398..1704728) 1 NC_008527.1 MutS family DNA structure-specific ATPase 1704728 4432442 LACR_1809 Lactococcus lactis subsp. cremoris SK11 MutS family DNA structure-specific ATPase YP_811414.1 1702398 R 272622 CDS YP_811415.1 116512508 4432443 complement(1704772..1705332) 1 NC_008527.1 hypothetical protein 1705332 4432443 LACR_1810 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811415.1 1704772 R 272622 CDS YP_811416.1 116512509 4432444 complement(1705641..1706606) 1 NC_008527.1 thioredoxin reductase 1706606 4432444 LACR_1811 Lactococcus lactis subsp. cremoris SK11 thioredoxin reductase YP_811416.1 1705641 R 272622 CDS YP_811417.1 116512510 4432445 complement(1706740..1707735) 1 NC_008527.1 LacI family transcription regulator 1707735 4432445 LACR_1812 Lactococcus lactis subsp. cremoris SK11 LacI family transcription regulator YP_811417.1 1706740 R 272622 CDS YP_811418.1 116512511 4432446 1707949..1709037 1 NC_008527.1 proline dipeptidase 1709037 4432446 LACR_1813 Lactococcus lactis subsp. cremoris SK11 proline dipeptidase YP_811418.1 1707949 D 272622 CDS YP_811419.1 116512512 4434512 complement(1709026..1709148) 1 NC_008527.1 hypothetical protein 1709148 4434512 LACR_1814 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811419.1 1709026 R 272622 CDS YP_811420.1 116512513 4434513 complement(1709141..1711150) 1 NC_008527.1 hypothetical protein 1711150 4434513 LACR_1815 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811420.1 1709141 R 272622 CDS YP_811421.1 116512514 4434514 complement(1711332..1712486) 1 NC_008527.1 N6-adenine-specific DNA methylase 1712486 4434514 LACR_1816 Lactococcus lactis subsp. cremoris SK11 N6-adenine-specific DNA methylase YP_811421.1 1711332 R 272622 CDS YP_811422.1 116512515 4434516 complement(1713122..1713508) 1 NC_008527.1 cell division initiation protein 1713508 4434516 LACR_1818 Lactococcus lactis subsp. cremoris SK11 cell division initiation protein YP_811422.1 1713122 R 272622 CDS YP_811423.1 116512516 4434517 complement(1713562..1714566) 1 NC_008527.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1714566 holA 4434517 holA Lactococcus lactis subsp. cremoris SK11 DNA polymerase III subunit delta YP_811423.1 1713562 R 272622 CDS YP_811424.1 116512517 4434518 complement(1714568..1715146) 1 NC_008527.1 hypothetical protein 1715146 4434518 LACR_1820 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811424.1 1714568 R 272622 CDS YP_811425.1 116512518 4434519 complement(1715143..1717410) 1 NC_008527.1 DNA segregation ATPase FtsK/SpoIIIE related protein 1717410 4434519 LACR_1821 Lactococcus lactis subsp. cremoris SK11 DNA segregation ATPase FtsK/SpoIIIE related protein YP_811425.1 1715143 R 272622 CDS YP_811426.1 116512519 4434520 1717602..1718387 1 NC_008527.1 HAD superfamily hydrolase 1718387 4434520 LACR_1822 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_811426.1 1717602 D 272622 CDS YP_811427.1 116512520 4434521 complement(1718427..1718819) 1 NC_008527.1 hypothetical protein 1718819 4434521 LACR_1823 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811427.1 1718427 R 272622 CDS YP_811428.1 116512521 4434522 complement(1718957..1719937) 1 NC_008527.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1719937 eutD 4434522 eutD Lactococcus lactis subsp. cremoris SK11 phosphotransacetylase YP_811428.1 1718957 R 272622 CDS YP_811429.1 116512522 4434523 complement(1720153..1720773) 1 NC_008527.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1720773 4434523 LACR_1825 Lactococcus lactis subsp. cremoris SK11 uridine kinase YP_811429.1 1720153 R 272622 CDS YP_811430.1 116512523 4434524 1721070..1722050 1 NC_008527.1 dehydrogenase related protein 1722050 4434524 LACR_1826 Lactococcus lactis subsp. cremoris SK11 dehydrogenase related protein YP_811430.1 1721070 D 272622 CDS YP_811431.1 116512524 4434526 complement(1722316..1722915) 1 NC_008527.1 transglycosylase 1722915 4434526 LACR_1828 Lactococcus lactis subsp. cremoris SK11 transglycosylase YP_811431.1 1722316 R 272622 CDS YP_811432.1 116512525 4434527 1723585..1724544 1 NC_008527.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1724544 4434527 LACR_1829 Lactococcus lactis subsp. cremoris SK11 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_811432.1 1723585 D 272622 CDS YP_811433.1 116512526 4433459 complement(1724569..1726107) 1 NC_008527.1 chloride channel protein EriC 1726107 4433459 LACR_1830 Lactococcus lactis subsp. cremoris SK11 chloride channel protein EriC YP_811433.1 1724569 R 272622 CDS YP_811434.1 116512527 4433460 complement(1726275..1726508) 1 NC_008527.1 hypothetical protein 1726508 4433460 LACR_1831 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811434.1 1726275 R 272622 CDS YP_811435.1 116512528 4433461 complement(1726578..1726799) 1 NC_008527.1 hypothetical protein 1726799 4433461 LACR_1832 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811435.1 1726578 R 272622 CDS YP_811436.1 116512529 4433462 complement(1726880..1727194) 1 NC_008527.1 hypothetical protein 1727194 4433462 LACR_1833 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811436.1 1726880 R 272622 CDS YP_811437.1 116512530 4433463 complement(1727212..1727541) 1 NC_008527.1 hypothetical protein 1727541 4433463 LACR_1834 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811437.1 1727212 R 272622 CDS YP_811438.1 116512531 4433464 complement(1727728..1728561) 1 NC_008527.1 XRE family transcriptional regulator 1728561 4433464 LACR_1835 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_811438.1 1727728 R 272622 CDS YP_811439.1 116512532 4433465 complement(1728598..1729338) 1 NC_008527.1 demethylmenaquinone methyltransferase / 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase 1729338 4433465 LACR_1836 Lactococcus lactis subsp. cremoris SK11 demethylmenaquinone methyltransferase / 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase YP_811439.1 1728598 R 272622 CDS YP_811440.1 116512533 4433468 complement(1732279..1732407) 1 NC_008527.1 hypothetical protein 1732407 4433468 LACR_1839 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811440.1 1732279 R 272622 CDS YP_811441.1 116512534 4433470 complement(1732845..1733735) 1 NC_008527.1 transposase 1733735 4433470 LACR_1841 Lactococcus lactis subsp. cremoris SK11 transposase YP_811441.1 1732845 R 272622 CDS YP_811442.1 116512535 4433471 complement(1734963..1735235) 1 NC_008527.1 hypothetical protein 1735235 4433471 LACR_1842 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811442.1 1734963 R 272622 CDS YP_811443.1 116512536 4433472 complement(1735326..1737068) 1 NC_008527.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1737068 4433472 LACR_1843 Lactococcus lactis subsp. cremoris SK11 1-deoxy-D-xylulose-5-phosphate synthase YP_811443.1 1735326 R 272622 CDS YP_811444.1 116512537 4433473 complement(1737217..1738587) 1 NC_008527.1 Signal transduction histidine kinase 1738587 4433473 LACR_1844 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_811444.1 1737217 R 272622 CDS YP_811445.1 116512538 4433474 complement(1738803..1739480) 1 NC_008527.1 DNA-binding response regulator 1739480 4433474 LACR_1845 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_811445.1 1738803 R 272622 CDS YP_811446.1 116512539 4433475 complement(1739649..1740623) 1 NC_008527.1 LacI family transcription regulator 1740623 4433475 LACR_1846 Lactococcus lactis subsp. cremoris SK11 LacI family transcription regulator YP_811446.1 1739649 R 272622 CDS YP_811447.1 116512540 4433476 complement(1740775..1743030) 1 NC_008527.1 maltose phosphorylase 1743030 4433476 LACR_1847 Lactococcus lactis subsp. cremoris SK11 maltose phosphorylase YP_811447.1 1740775 R 272622 CDS YP_811448.1 116512541 4433477 complement(1743053..1744678) 1 NC_008527.1 alpha-glucosidase 1744678 4433477 LACR_1848 Lactococcus lactis subsp. cremoris SK11 alpha-glucosidase YP_811448.1 1743053 R 272622 CDS YP_811449.1 116512542 4433478 complement(1744721..1746295) 1 NC_008527.1 alpha-amylase 1746295 4433478 LACR_1849 Lactococcus lactis subsp. cremoris SK11 alpha-amylase YP_811449.1 1744721 R 272622 CDS YP_811450.1 116512543 4433479 complement(1746285..1746932) 1 NC_008527.1 maltose O-acetyltransferase 1746932 4433479 LACR_1850 Lactococcus lactis subsp. cremoris SK11 maltose O-acetyltransferase YP_811450.1 1746285 R 272622 CDS YP_811451.1 116512544 4433480 complement(1746917..1748512) 1 NC_008527.1 trehalose-6-phosphate hydrolase 1748512 4433480 LACR_1851 Lactococcus lactis subsp. cremoris SK11 trehalose-6-phosphate hydrolase YP_811451.1 1746917 R 272622 CDS YP_811452.1 116512545 4433481 complement(1748809..1750563) 1 NC_008527.1 neopullulanase 1750563 4433481 LACR_1852 Lactococcus lactis subsp. cremoris SK11 neopullulanase YP_811452.1 1748809 R 272622 CDS YP_811453.1 116512546 4433482 1750935..1752164 1 NC_008527.1 maltose ABC transporter substrate binding protein 1752164 4433482 LACR_1853 Lactococcus lactis subsp. cremoris SK11 maltose ABC transporter substrate binding protein YP_811453.1 1750935 D 272622 CDS YP_811454.1 116512547 4433483 1752236..1753594 1 NC_008527.1 ABC-type sugar transport system, permease component 1753594 4433483 LACR_1854 Lactococcus lactis subsp. cremoris SK11 ABC-type sugar transport system, permease component YP_811454.1 1752236 D 272622 CDS YP_811455.1 116512548 4433484 1753598..1754455 1 NC_008527.1 ABC-type maltose transport system, permease component 1754455 4433484 LACR_1855 Lactococcus lactis subsp. cremoris SK11 ABC-type maltose transport system, permease component YP_811455.1 1753598 D 272622 CDS YP_811456.1 116512549 4433485 1754628..1755518 1 NC_008527.1 hypothetical protein 1755518 4433485 LACR_1856 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811456.1 1754628 D 272622 CDS YP_811457.1 116512550 4433486 1755575..1756366 1 NC_008527.1 transposase 1756366 4433486 LACR_1857 Lactococcus lactis subsp. cremoris SK11 transposase YP_811457.1 1755575 D 272622 CDS YP_811458.1 116512551 4433487 complement(1756722..1757342) 1 NC_008527.1 amidase 1757342 4433487 LACR_1858 Lactococcus lactis subsp. cremoris SK11 amidase YP_811458.1 1756722 R 272622 CDS YP_811459.1 116512552 4433488 complement(1757582..1758973) 1 NC_008527.1 transcriptional regulator 1758973 4433488 LACR_1859 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811459.1 1757582 R 272622 CDS YP_811460.1 116512553 4433489 complement(1759053..1759715) 1 NC_008527.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1759715 cmk 4433489 cmk Lactococcus lactis subsp. cremoris SK11 cytidylate kinase YP_811460.1 1759053 R 272622 CDS YP_811461.1 116512554 4433490 complement(1759835..1760347) 1 NC_008527.1 LysM domain-containing protein 1760347 4433490 LACR_1861 Lactococcus lactis subsp. cremoris SK11 LysM domain-containing protein YP_811461.1 1759835 R 272622 CDS YP_811462.1 116512555 4433491 1760394..1760597 1 NC_008527.1 ferredoxin 1760597 4433491 LACR_1862 Lactococcus lactis subsp. cremoris SK11 ferredoxin YP_811462.1 1760394 D 272622 CDS YP_811463.1 116512556 4433492 1760867..1761856 1 NC_008527.1 phosphotransferase system, mannose/fructose-specific component IIA 1761856 4433492 LACR_1863 Lactococcus lactis subsp. cremoris SK11 phosphotransferase system, mannose/fructose-specific component IIA YP_811463.1 1760867 D 272622 CDS YP_811464.1 116512557 4433493 1761935..1762747 1 NC_008527.1 mannose-specific PTS system component IIC 1762747 4433493 LACR_1864 Lactococcus lactis subsp. cremoris SK11 mannose-specific PTS system component IIC YP_811464.1 1761935 D 272622 CDS YP_811465.1 116512558 4432277 1762766..1763689 1 NC_008527.1 mannose-specific PTS system component IID 1763689 4432277 LACR_1865 Lactococcus lactis subsp. cremoris SK11 mannose-specific PTS system component IID YP_811465.1 1762766 D 272622 CDS YP_811466.1 116512559 4432278 1763832..1764215 1 NC_008527.1 hypothetical protein 1764215 4432278 LACR_1866 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811466.1 1763832 D 272622 CDS YP_811467.1 116512560 4432280 complement(1764244..1764939) 1 NC_008527.1 hypothetical protein 1764939 4432280 LACR_1868 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811467.1 1764244 R 272622 CDS YP_811468.1 116512561 4432281 1765090..1765449 1 NC_008527.1 hypothetical protein 1765449 4432281 LACR_1869 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811468.1 1765090 D 272622 CDS YP_811469.1 116512562 4432282 1765848..1767119 1 NC_008527.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1767119 4432282 LACR_1870 Lactococcus lactis subsp. cremoris SK11 seryl-tRNA synthetase YP_811469.1 1765848 D 272622 CDS YP_811470.1 116512563 4432283 complement(1767394..1768248) 1 NC_008527.1 transposase 1768248 4432283 LACR_1871 Lactococcus lactis subsp. cremoris SK11 transposase YP_811470.1 1767394 R 272622 CDS YP_811471.1 116512564 4432284 complement(1768245..1768505) 1 NC_008527.1 transposase 1768505 4432284 LACR_1872 Lactococcus lactis subsp. cremoris SK11 transposase YP_811471.1 1768245 R 272622 CDS YP_811472.1 116512565 4432285 complement(1768697..1768846) 1 NC_008527.1 hypothetical protein 1768846 4432285 LACR_1873 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811472.1 1768697 R 272622 CDS YP_811473.1 116512566 4432286 1769309..1770283 1 NC_008527.1 microcin C7 resistance-like protein (MccF) 1770283 4432286 LACR_1874 Lactococcus lactis subsp. cremoris SK11 microcin C7 resistance-like protein (MccF) YP_811473.1 1769309 D 272622 CDS YP_811474.1 116512567 4432287 1770305..1770886 1 NC_008527.1 phosphoglycerate mutase 1770886 4432287 LACR_1875 Lactococcus lactis subsp. cremoris SK11 phosphoglycerate mutase YP_811474.1 1770305 D 272622 CDS YP_811475.1 116512568 4432288 complement(1770968..1771621) 1 NC_008527.1 phosphate uptake regulator, PhoU 1771621 4432288 LACR_1876 Lactococcus lactis subsp. cremoris SK11 phosphate uptake regulator, PhoU YP_811475.1 1770968 R 272622 CDS YP_811476.1 116512569 4432289 complement(1771864..1772625) 1 NC_008527.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1772625 4432289 LACR_1877 Lactococcus lactis subsp. cremoris SK11 phosphate transporter ATP-binding protein YP_811476.1 1771864 R 272622 CDS YP_811477.1 116512570 4432290 complement(1772833..1773642) 1 NC_008527.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1773642 4432290 LACR_1878 Lactococcus lactis subsp. cremoris SK11 phosphate transporter ATP-binding protein YP_811477.1 1772833 R 272622 CDS YP_811478.1 116512571 4432291 complement(1773675..1774568) 1 NC_008527.1 ABC-type phosphate transport system, permease component 1774568 4432291 LACR_1879 Lactococcus lactis subsp. cremoris SK11 ABC-type phosphate transport system, permease component YP_811478.1 1773675 R 272622 CDS YP_811479.1 116512572 4432292 complement(1774568..1775491) 1 NC_008527.1 ABC-type phosphate transport system, permease component 1775491 4432292 LACR_1880 Lactococcus lactis subsp. cremoris SK11 ABC-type phosphate transport system, permease component YP_811479.1 1774568 R 272622 CDS YP_811480.1 116512573 4432293 complement(1775632..1776483) 1 NC_008527.1 ABC-type phosphate transport system, periplasmic component 1776483 4432293 LACR_1881 Lactococcus lactis subsp. cremoris SK11 ABC-type phosphate transport system, periplasmic component YP_811480.1 1775632 R 272622 CDS YP_811481.1 116512574 4434546 complement(1776823..1777719) 1 NC_008527.1 ABC-type phosphate transport system, periplasmic component 1777719 4434546 LACR_1882 Lactococcus lactis subsp. cremoris SK11 ABC-type phosphate transport system, periplasmic component YP_811481.1 1776823 R 272622 CDS YP_811482.1 116512575 4434547 complement(1777931..1778398) 1 NC_008527.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1778398 smpB 4434547 smpB Lactococcus lactis subsp. cremoris SK11 SsrA-binding protein YP_811482.1 1777931 R 272622 CDS YP_811483.1 116512576 4434548 complement(1778463..1778765) 1 NC_008527.1 transcriptional regulator 1778765 4434548 LACR_1884 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811483.1 1778463 R 272622 CDS YP_811484.1 116512577 4434549 1778867..1779478 1 NC_008527.1 nitroreductase 1779478 4434549 LACR_1885 Lactococcus lactis subsp. cremoris SK11 nitroreductase YP_811484.1 1778867 D 272622 CDS YP_811485.1 116512578 4434550 complement(1779468..1780031) 1 NC_008527.1 lysophospholipase L1 related esterase 1780031 4434550 LACR_1886 Lactococcus lactis subsp. cremoris SK11 lysophospholipase L1 related esterase YP_811485.1 1779468 R 272622 CDS YP_811486.1 116512579 4434551 complement(1780128..1782746) 1 NC_008527.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1782746 alaS 4434551 alaS Lactococcus lactis subsp. cremoris SK11 alanyl-tRNA synthetase YP_811486.1 1780128 R 272622 CDS YP_811487.1 116512580 4434552 complement(1783008..1783934) 1 NC_008527.1 parvulin-like peptidyl-prolyl isomerase 1783934 4434552 LACR_1888 Lactococcus lactis subsp. cremoris SK11 parvulin-like peptidyl-prolyl isomerase YP_811487.1 1783008 R 272622 CDS YP_811488.1 116512581 4434553 complement(1784090..1784773) 1 NC_008527.1 O-methyltransferase 1784773 4434553 LACR_1889 Lactococcus lactis subsp. cremoris SK11 O-methyltransferase YP_811488.1 1784090 R 272622 CDS YP_811489.1 116512582 4434554 complement(1784776..1786581) 1 NC_008527.1 oligopeptidase F 1786581 4434554 LACR_1890 Lactococcus lactis subsp. cremoris SK11 oligopeptidase F YP_811489.1 1784776 R 272622 CDS YP_811490.1 116512583 4434555 complement(1786656..1787639) 1 NC_008527.1 competence protein 1787639 4434555 LACR_1891 Lactococcus lactis subsp. cremoris SK11 competence protein YP_811490.1 1786656 R 272622 CDS YP_811491.1 116512584 4434556 complement(1787714..1788799) 1 NC_008527.1 hypothetical protein 1788799 4434556 LACR_1892 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811491.1 1787714 R 272622 CDS YP_811492.1 116512585 4434558 complement(1790009..1791430) 1 NC_008527.1 xanthine/uracil/vitamin C permease 1791430 4434558 LACR_1894 Lactococcus lactis subsp. cremoris SK11 xanthine/uracil/vitamin C permease YP_811492.1 1790009 R 272622 CDS YP_811493.1 116512586 4434559 1791736..1792572 1 NC_008527.1 HAD superfamily hydrolase 1792572 4434559 LACR_1895 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_811493.1 1791736 D 272622 CDS YP_811494.1 116512587 4434560 1792753..1793523 1 NC_008527.1 Fe-S oxidoreductase 1793523 4434560 LACR_1896 Lactococcus lactis subsp. cremoris SK11 Fe-S oxidoreductase YP_811494.1 1792753 D 272622 CDS YP_811495.1 116512588 4434562 1795007..1795690 1 NC_008527.1 hypothetical protein 1795690 4434562 LACR_1898 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811495.1 1795007 D 272622 CDS YP_811496.1 116512589 4434563 complement(1795767..1796480) 1 NC_008527.1 integral membrane protein, interacts with FtsH 1796480 4434563 LACR_1899 Lactococcus lactis subsp. cremoris SK11 integral membrane protein, interacts with FtsH YP_811496.1 1795767 R 272622 CDS YP_811497.1 116512590 4432227 complement(1796594..1797508) 1 NC_008527.1 diacylglycerol kinase family lipid kinase 1797508 4432227 LACR_1900 Lactococcus lactis subsp. cremoris SK11 diacylglycerol kinase family lipid kinase YP_811497.1 1796594 R 272622 CDS YP_811498.1 116512591 4432228 complement(1797688..1798158) 1 NC_008527.1 HD superfamily hydrolase 1798158 4432228 LACR_1901 Lactococcus lactis subsp. cremoris SK11 HD superfamily hydrolase YP_811498.1 1797688 R 272622 CDS YP_811499.1 116512592 4432229 1798528..1798761 1 NC_008527.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1798761 rpsT 4432229 rpsT Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S20 YP_811499.1 1798528 D 272622 CDS YP_811500.1 116512593 4432230 complement(1798855..1801356) 1 NC_008527.1 ATP-dependent RecD/TraA family DNA helicase 1801356 4432230 LACR_1903 Lactococcus lactis subsp. cremoris SK11 ATP-dependent RecD/TraA family DNA helicase YP_811500.1 1798855 R 272622 CDS YP_811501.1 116512594 4432231 complement(1801353..1801946) 1 NC_008527.1 phosphoglycerate mutase 1801946 4432231 LACR_1904 Lactococcus lactis subsp. cremoris SK11 phosphoglycerate mutase YP_811501.1 1801353 R 272622 CDS YP_811502.1 116512595 4432232 complement(1801949..1802788) 1 NC_008527.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 1802788 4432232 LACR_1905 Lactococcus lactis subsp. cremoris SK11 prephenate dehydratase YP_811502.1 1801949 R 272622 CDS YP_811503.1 116512596 4432233 complement(1802790..1803278) 1 NC_008527.1 shikimate kinase 1803278 4432233 LACR_1906 Lactococcus lactis subsp. cremoris SK11 shikimate kinase YP_811503.1 1802790 R 272622 CDS YP_811504.1 116512597 4432234 complement(1803302..1804594) 1 NC_008527.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1804594 4432234 LACR_1907 Lactococcus lactis subsp. cremoris SK11 3-phosphoshikimate 1-carboxyvinyltransferase YP_811504.1 1803302 R 272622 CDS YP_811505.1 116512598 4432235 complement(1804715..1805779) 1 NC_008527.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1805779 4432235 LACR_1908 Lactococcus lactis subsp. cremoris SK11 prephenate dehydrogenase YP_811505.1 1804715 R 272622 CDS YP_811506.1 116512599 4432236 complement(1805783..1806658) 1 NC_008527.1 Signal transduction histidine kinase 1806658 4432236 LACR_1909 Lactococcus lactis subsp. cremoris SK11 Signal transduction histidine kinase YP_811506.1 1805783 R 272622 CDS YP_811507.1 116512600 4432237 complement(1806645..1807316) 1 NC_008527.1 DNA-binding response regulator 1807316 4432237 LACR_1910 Lactococcus lactis subsp. cremoris SK11 DNA-binding response regulator YP_811507.1 1806645 R 272622 CDS YP_811508.1 116512601 4432238 complement(1807319..1808383) 1 NC_008527.1 hypothetical protein 1808383 4432238 LACR_1911 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811508.1 1807319 R 272622 CDS YP_811509.1 116512602 4432239 complement(1808569..1810578) 1 NC_008527.1 peptide ABC transporter permease 1810578 4432239 LACR_1912 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter permease YP_811509.1 1808569 R 272622 CDS YP_811510.1 116512603 4432240 complement(1810571..1811350) 1 NC_008527.1 peptide ABC transporter ATPase 1811350 4432240 LACR_1913 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter ATPase YP_811510.1 1810571 R 272622 CDS YP_811511.1 116512604 4432241 complement(1811365..1811508) 1 NC_008527.1 hypothetical protein 1811508 4432241 LACR_1914 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811511.1 1811365 R 272622 CDS YP_811512.1 116512605 4432242 complement(1811545..1811901) 1 NC_008527.1 hypothetical protein 1811901 4432242 LACR_1915 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811512.1 1811545 R 272622 CDS YP_811513.1 116512606 4432243 complement(1812023..1813189) 1 NC_008527.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1813189 4432243 LACR_1916 Lactococcus lactis subsp. cremoris SK11 chorismate synthase YP_811513.1 1812023 R 272622 CDS YP_811514.1 116512607 4433891 complement(1813220..1813816) 1 NC_008527.1 phosphatase 1813816 4433891 LACR_1917 Lactococcus lactis subsp. cremoris SK11 phosphatase YP_811514.1 1813220 R 272622 CDS YP_811515.1 116512608 4433892 complement(1813821..1814420) 1 NC_008527.1 hypothetical protein 1814420 4433892 LACR_1918 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811515.1 1813821 R 272622 CDS YP_811516.1 116512609 4433893 complement(1814792..1815715) 1 NC_008527.1 hypothetical protein 1815715 4433893 LACR_1919 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811516.1 1814792 R 272622 CDS YP_811517.1 116512610 4433894 complement(1815829..1816899) 1 NC_008527.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1816899 aroB 4433894 aroB Lactococcus lactis subsp. cremoris SK11 3-dehydroquinate synthase YP_811517.1 1815829 R 272622 CDS YP_811518.1 116512611 4433895 complement(1816896..1817756) 1 NC_008527.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1817756 aroE 4433895 aroE Lactococcus lactis subsp. cremoris SK11 shikimate 5-dehydrogenase YP_811518.1 1816896 R 272622 CDS YP_811519.1 116512612 4433896 complement(1817934..1818590) 1 NC_008527.1 hypothetical protein 1818590 4433896 LACR_1922 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811519.1 1817934 R 272622 CDS YP_811520.1 116512613 4433897 1818958..1821102 1 NC_008527.1 amino acid ABC transporter permease/periplasmic protein 1821102 4433897 LACR_1923 Lactococcus lactis subsp. cremoris SK11 amino acid ABC transporter permease/periplasmic protein YP_811520.1 1818958 D 272622 CDS YP_811521.1 116512614 4433898 1821125..1821868 1 NC_008527.1 glutamine ABC transporter ATP-binding protein 1821868 4433898 LACR_1924 Lactococcus lactis subsp. cremoris SK11 glutamine ABC transporter ATP-binding protein YP_811521.1 1821125 D 272622 CDS YP_811522.1 116512615 4433899 complement(1821925..1822068) 1 NC_008527.1 hypothetical protein 1822068 4433899 LACR_1925 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811522.1 1821925 R 272622 CDS YP_811523.1 116512616 4433900 complement(1822146..1822472) 1 NC_008527.1 hypothetical protein 1822472 4433900 LACR_1926 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811523.1 1822146 R 272622 CDS YP_811524.1 116512617 4433901 complement(1822580..1822828) 1 NC_008527.1 hypothetical protein 1822828 4433901 LACR_1927 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811524.1 1822580 R 272622 CDS YP_811525.1 116512618 4433902 complement(1822885..1823739) 1 NC_008527.1 transposase 1823739 4433902 LACR_1928 Lactococcus lactis subsp. cremoris SK11 transposase YP_811525.1 1822885 R 272622 CDS YP_811526.1 116512619 4433903 complement(1823736..1823996) 1 NC_008527.1 transposase 1823996 4433903 LACR_1929 Lactococcus lactis subsp. cremoris SK11 transposase YP_811526.1 1823736 R 272622 CDS YP_811527.1 116512620 4433904 complement(1824017..1824757) 1 NC_008527.1 hypothetical protein 1824757 4433904 LACR_1930 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811527.1 1824017 R 272622 CDS YP_811528.1 116512621 4433905 complement(1824758..1825264) 1 NC_008527.1 hypothetical protein 1825264 4433905 LACR_1931 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811528.1 1824758 R 272622 CDS YP_811529.1 116512622 4433906 complement(1825520..1825945) 1 NC_008527.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1825945 atpC 4433906 atpC Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit epsilon YP_811529.1 1825520 R 272622 CDS YP_811530.1 116512623 4433907 complement(1826130..1827539) 1 NC_008527.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1827539 4433907 LACR_1933 Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit beta YP_811530.1 1826130 R 272622 CDS YP_811531.1 116512624 4433908 complement(1827711..1828580) 1 NC_008527.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1828580 4433908 LACR_1934 Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit gamma YP_811531.1 1827711 R 272622 CDS YP_811532.1 116512625 4432141 complement(1828596..1830098) 1 NC_008527.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1830098 4432141 LACR_1935 Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit alpha YP_811532.1 1828596 R 272622 CDS YP_811533.1 116512626 4432142 complement(1830286..1830813) 1 NC_008527.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1830813 4432142 LACR_1936 Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit delta YP_811533.1 1830286 R 272622 CDS YP_811534.1 116512627 4432143 complement(1830815..1831321) 1 NC_008527.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1831321 4432143 LACR_1937 Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit B YP_811534.1 1830815 R 272622 CDS YP_811535.1 116512628 4432144 complement(1831336..1832049) 1 NC_008527.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1832049 4432144 LACR_1938 Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit A YP_811535.1 1831336 R 272622 CDS YP_811536.1 116512629 4432145 complement(1832096..1832311) 1 NC_008527.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1832311 4432145 LACR_1939 Lactococcus lactis subsp. cremoris SK11 F0F1 ATP synthase subunit C YP_811536.1 1832096 R 272622 CDS YP_811537.1 116512630 4432146 complement(1832494..1833270) 1 NC_008527.1 esterase 1833270 4432146 LACR_1940 Lactococcus lactis subsp. cremoris SK11 esterase YP_811537.1 1832494 R 272622 CDS YP_811538.1 116512631 4432147 complement(1833377..1833493) 1 NC_008527.1 hypothetical protein 1833493 4432147 LACR_1941 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811538.1 1833377 R 272622 CDS YP_811539.1 116512632 4432149 complement(1833880..1834770) 1 NC_008527.1 transposase 1834770 4432149 LACR_1943 Lactococcus lactis subsp. cremoris SK11 transposase YP_811539.1 1833880 R 272622 CDS YP_811540.1 116512633 4432150 complement(1836752..1837354) 1 NC_008527.1 DNA uptake protein related DNA-binding protein 1837354 4432150 LACR_1944 Lactococcus lactis subsp. cremoris SK11 DNA uptake protein related DNA-binding protein YP_811540.1 1836752 R 272622 CDS YP_811541.1 116512634 4432151 complement(1837464..1838825) 1 NC_008527.1 ABC-type Na+ efflux pump, permease component 1838825 4432151 LACR_1945 Lactococcus lactis subsp. cremoris SK11 ABC-type Na+ efflux pump, permease component YP_811541.1 1837464 R 272622 CDS YP_811542.1 116512635 4432152 complement(1838822..1839751) 1 NC_008527.1 ABC-type uncharacterized transport system, ATPase component 1839751 4432152 LACR_1946 Lactococcus lactis subsp. cremoris SK11 ABC-type uncharacterized transport system, ATPase component YP_811542.1 1838822 R 272622 CDS YP_811543.1 116512636 4432153 complement(1839857..1840255) 1 NC_008527.1 hypothetical protein 1840255 4432153 LACR_1947 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811543.1 1839857 R 272622 CDS YP_811544.1 116512637 4432154 complement(1840372..1840932) 1 NC_008527.1 sortase related acyltransferase 1840932 4432154 LACR_1948 Lactococcus lactis subsp. cremoris SK11 sortase related acyltransferase YP_811544.1 1840372 R 272622 CDS YP_811545.1 116512638 4432155 complement(1841105..1842283) 1 NC_008527.1 di- or tricarboxylate transporter 1842283 4432155 LACR_1949 Lactococcus lactis subsp. cremoris SK11 di- or tricarboxylate transporter YP_811545.1 1841105 R 272622 CDS YP_811546.1 116512639 4432156 complement(1842671..1843327) 1 NC_008527.1 transcriptional regulator 1843327 4432156 LACR_1950 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811546.1 1842671 R 272622 CDS YP_811547.1 116512640 4432157 complement(1843546..1843848) 1 NC_008527.1 hypothetical protein 1843848 4432157 LACR_1951 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811547.1 1843546 R 272622 CDS YP_811548.1 116512641 4432948 complement(1843869..1844840) 1 NC_008527.1 biotin operon repressor 1844840 4432948 LACR_1952 Lactococcus lactis subsp. cremoris SK11 biotin operon repressor YP_811548.1 1843869 R 272622 CDS YP_811549.1 116512642 4432949 complement(1844846..1845415) 1 NC_008527.1 hypothetical protein 1845415 4432949 LACR_1953 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811549.1 1844846 R 272622 CDS YP_811550.1 116512643 4432950 1845616..1846506 1 NC_008527.1 transposase 1846506 4432950 LACR_1954 Lactococcus lactis subsp. cremoris SK11 transposase YP_811550.1 1845616 D 272622 CDS YP_811551.1 116512644 4432951 1846559..1847803 1 NC_008527.1 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II 1847803 4432951 LACR_1955 Lactococcus lactis subsp. cremoris SK11 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II YP_811551.1 1846559 D 272622 CDS YP_811552.1 116512645 4432952 1847793..1848941 1 NC_008527.1 Acetyl-CoA acetyltransferase 1848941 4432952 LACR_1956 Lactococcus lactis subsp. cremoris SK11 Acetyl-CoA acetyltransferase YP_811552.1 1847793 D 272622 CDS YP_811553.1 116512646 4432953 1849103..1849315 1 NC_008527.1 hypothetical protein 1849315 4432953 LACR_1957 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811553.1 1849103 D 272622 CDS YP_811554.1 116512647 4432954 1849290..1849583 1 NC_008527.1 hypothetical protein 1849583 4432954 LACR_1958 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811554.1 1849290 D 272622 CDS YP_811555.1 116512648 4432956 1849876..1850325 1 NC_008527.1 3-oxoacyl-ACP reductase 1850325 4432956 LACR_1960 Lactococcus lactis subsp. cremoris SK11 3-oxoacyl-ACP reductase YP_811555.1 1849876 D 272622 CDS YP_811556.1 116512649 4432957 1850342..1851187 1 NC_008527.1 dioxygenase 1851187 4432957 LACR_1961 Lactococcus lactis subsp. cremoris SK11 dioxygenase YP_811556.1 1850342 D 272622 CDS YP_811557.1 116512650 4432958 complement(1851334..1854144) 1 NC_008527.1 hypothetical protein 1854144 4432958 LACR_1962 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811557.1 1851334 R 272622 CDS YP_811558.1 116512651 4432959 complement(1854207..1854644) 1 NC_008527.1 hypothetical protein 1854644 4432959 LACR_1963 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811558.1 1854207 R 272622 CDS YP_811559.1 116512652 4432960 complement(1854673..1855335) 1 NC_008527.1 hypothetical protein 1855335 4432960 LACR_1964 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811559.1 1854673 R 272622 CDS YP_811560.1 116512653 4432961 1855542..1855802 1 NC_008527.1 transposase 1855802 4432961 LACR_1965 Lactococcus lactis subsp. cremoris SK11 transposase YP_811560.1 1855542 D 272622 CDS YP_811561.1 116512654 4432962 1855799..1856653 1 NC_008527.1 transposase 1856653 4432962 LACR_1966 Lactococcus lactis subsp. cremoris SK11 transposase YP_811561.1 1855799 D 272622 CDS YP_811562.1 116512655 4432963 complement(1856686..1857099) 1 NC_008527.1 hypothetical protein 1857099 4432963 LACR_1967 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811562.1 1856686 R 272622 CDS YP_811563.1 116512656 4432964 complement(1857207..1857497) 1 NC_008527.1 hypothetical protein 1857497 4432964 LACR_1968 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811563.1 1857207 R 272622 CDS YP_811564.1 116512657 4432965 complement(1857869..1859281) 1 NC_008527.1 hypothetical protein 1859281 4432965 LACR_1969 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811564.1 1857869 R 272622 CDS YP_811565.1 116512658 4432628 complement(1859377..1859835) 1 NC_008527.1 NifU-like protein for Fe-S cluster formation 1859835 4432628 LACR_1970 Lactococcus lactis subsp. cremoris SK11 NifU-like protein for Fe-S cluster formation YP_811565.1 1859377 R 272622 CDS YP_811566.1 116512659 4432629 complement(1859969..1860460) 1 NC_008527.1 hypothetical protein 1860460 4432629 LACR_1971 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811566.1 1859969 R 272622 CDS YP_811567.1 116512660 4432630 complement(1860453..1861670) 1 NC_008527.1 hypothetical protein 1861670 4432630 LACR_1972 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811567.1 1860453 R 272622 CDS YP_811568.1 116512661 4432631 complement(1861670..1862926) 1 NC_008527.1 hypothetical protein 1862926 4432631 LACR_1973 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811568.1 1861670 R 272622 CDS YP_811569.1 116512662 4432632 complement(1863066..1863836) 1 NC_008527.1 ABC-type transport system for Fe-S cluster assembly, ATPase component 1863836 4432632 LACR_1974 Lactococcus lactis subsp. cremoris SK11 ABC-type transport system for Fe-S cluster assembly, ATPase component YP_811569.1 1863066 R 272622 CDS YP_811570.1 116512663 4432633 complement(1864012..1865337) 1 NC_008527.1 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase 1865337 4432633 LACR_1975 Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase YP_811570.1 1864012 R 272622 CDS YP_811571.1 116512664 4432634 complement(1865340..1866041) 1 NC_008527.1 negative regulator of genetic competence, sporulation and motility 1866041 4432634 LACR_1976 Lactococcus lactis subsp. cremoris SK11 negative regulator of genetic competence, sporulation and motility YP_811571.1 1865340 R 272622 CDS YP_811572.1 116512665 4432635 complement(1866169..1866903) 1 NC_008527.1 glutamate ABC transporter ATP-binding protein 1866903 4432635 LACR_1977 Lactococcus lactis subsp. cremoris SK11 glutamate ABC transporter ATP-binding protein YP_811572.1 1866169 R 272622 CDS YP_811573.1 116512666 4432636 complement(1866903..1867589) 1 NC_008527.1 glutamate ABC transporter permease protein 1867589 4432636 LACR_1978 Lactococcus lactis subsp. cremoris SK11 glutamate ABC transporter permease protein YP_811573.1 1866903 R 272622 CDS YP_811574.1 116512667 4432637 complement(1867735..1868643) 1 NC_008527.1 diacylglycerol kinase family protein 1868643 4432637 LACR_1979 Lactococcus lactis subsp. cremoris SK11 diacylglycerol kinase family protein YP_811574.1 1867735 R 272622 CDS YP_811575.1 116512668 4432638 complement(1868767..1872390) 1 NC_008527.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1872390 4432638 LACR_1980 Lactococcus lactis subsp. cremoris SK11 DNA-directed RNA polymerase subunit beta' YP_811575.1 1868767 R 272622 CDS YP_811576.1 116512669 4432639 complement(1872498..1876088) 1 NC_008527.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1876088 rpoB 4432639 rpoB Lactococcus lactis subsp. cremoris SK11 DNA-directed RNA polymerase subunit beta YP_811576.1 1872498 R 272622 CDS YP_811577.1 116512670 4432640 complement(1876357..1876956) 1 NC_008527.1 pleiotropic transcriptional repressor 1876956 4432640 LACR_1982 Lactococcus lactis subsp. cremoris SK11 pleiotropic transcriptional repressor YP_811577.1 1876357 R 272622 CDS YP_811578.1 116512671 4432641 1877192..1877866 1 NC_008527.1 XRE family transcriptional regulator 1877866 4432641 LACR_1983 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_811578.1 1877192 D 272622 CDS YP_811579.1 116512672 4432642 1877981..1879864 1 NC_008527.1 oligopeptidase O1 1879864 4432642 LACR_1984 Lactococcus lactis subsp. cremoris SK11 oligopeptidase O1 YP_811579.1 1877981 D 272622 CDS YP_811580.1 116512673 4432643 complement(1879913..1880218) 1 NC_008527.1 hypothetical protein 1880218 4432643 LACR_1985 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811580.1 1879913 R 272622 CDS YP_811581.1 116512674 4432644 complement(1880288..1881961) 1 NC_008527.1 hypothetical protein 1881961 4432644 LACR_1986 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811581.1 1880288 R 272622 CDS YP_811582.1 116512675 4432850 1882172..1883623 1 NC_008527.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1883623 murE 4432850 murE Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_811582.1 1882172 D 272622 CDS YP_811583.1 116512676 4432851 complement(1883705..1883965) 1 NC_008527.1 hypothetical protein 1883965 4432851 LACR_1988 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811583.1 1883705 R 272622 CDS YP_811584.1 116512677 4432852 1884083..1884973 1 NC_008527.1 transposase 1884973 4432852 LACR_1989 Lactococcus lactis subsp. cremoris SK11 transposase YP_811584.1 1884083 D 272622 CDS YP_811585.1 116512678 4432853 complement(1884993..1886015) 1 NC_008527.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1886015 4432853 LACR_1990 Lactococcus lactis subsp. cremoris SK11 alcohol dehydrogenase YP_811585.1 1884993 R 272622 CDS YP_811586.1 116512679 4432854 1886235..1888016 1 NC_008527.1 ATP-dependent DNA helicase RecQ 1888016 4432854 LACR_1991 Lactococcus lactis subsp. cremoris SK11 ATP-dependent DNA helicase RecQ YP_811586.1 1886235 D 272622 CDS YP_811587.1 116512680 4432855 complement(1888396..1888578) 1 NC_008527.1 hypothetical protein 1888578 4432855 LACR_1992 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811587.1 1888396 R 272622 CDS YP_811588.1 116512681 4432856 complement(1888785..1889639) 1 NC_008527.1 transposase 1889639 4432856 LACR_1993 Lactococcus lactis subsp. cremoris SK11 transposase YP_811588.1 1888785 R 272622 CDS YP_811589.1 116512682 4432857 complement(1889636..1889896) 1 NC_008527.1 transposase 1889896 4432857 LACR_1994 Lactococcus lactis subsp. cremoris SK11 transposase YP_811589.1 1889636 R 272622 CDS YP_811590.1 116512683 4432858 complement(1890157..1891680) 1 NC_008527.1 amino acid transporter 1891680 4432858 LACR_1995 Lactococcus lactis subsp. cremoris SK11 amino acid transporter YP_811590.1 1890157 R 272622 CDS YP_811591.1 116512684 4432859 complement(1891963..1893204) 1 NC_008527.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1893204 4432859 LACR_1996 Lactococcus lactis subsp. cremoris SK11 peptidase T YP_811591.1 1891963 R 272622 CDS YP_811592.1 116512685 4432860 complement(1893233..1894030) 1 NC_008527.1 hypothetical protein 1894030 4432860 LACR_1997 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811592.1 1893233 R 272622 CDS YP_811593.1 116512686 4432861 complement(1894030..1894974) 1 NC_008527.1 catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase 1894974 4432861 LACR_1998 Lactococcus lactis subsp. cremoris SK11 putative manganese-dependent inorganic pyrophosphatase YP_811593.1 1894030 R 272622 CDS YP_811594.1 116512687 4432862 complement(1895175..1895966) 1 NC_008527.1 pyruvate-formate lyase activating enzyme 1895966 4432862 LACR_1999 Lactococcus lactis subsp. cremoris SK11 pyruvate-formate lyase activating enzyme YP_811594.1 1895175 R 272622 CDS YP_811595.1 116512688 4432863 complement(1896185..1897522) 1 NC_008527.1 hemolysin-like protein 1897522 4432863 LACR_2000 Lactococcus lactis subsp. cremoris SK11 hemolysin-like protein YP_811595.1 1896185 R 272622 CDS YP_811596.1 116512689 4432864 complement(1897642..1898757) 1 NC_008527.1 permease 1898757 4432864 LACR_2001 Lactococcus lactis subsp. cremoris SK11 permease YP_811596.1 1897642 R 272622 CDS YP_811597.1 116512690 4432865 complement(1899061..1899525) 1 NC_008527.1 BadM/Rrf2 family transcriptional regulator 1899525 4432865 LACR_2002 Lactococcus lactis subsp. cremoris SK11 BadM/Rrf2 family transcriptional regulator YP_811597.1 1899061 R 272622 CDS YP_811598.1 116512691 4432867 1900338..1900790 1 NC_008527.1 acetyltransferase 1900790 4432867 LACR_2004 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_811598.1 1900338 D 272622 CDS YP_811599.1 116512692 4432833 complement(1900847..1901260) 1 NC_008527.1 cell wall-associated hydrolase 1901260 4432833 LACR_2005 Lactococcus lactis subsp. cremoris SK11 cell wall-associated hydrolase YP_811599.1 1900847 R 272622 CDS YP_811600.1 116512693 4432834 1901334..1901792 1 NC_008527.1 hypothetical protein 1901792 4432834 LACR_2006 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811600.1 1901334 D 272622 CDS YP_811601.1 116512694 4432835 complement(1901793..1902683) 1 NC_008527.1 transposase 1902683 4432835 LACR_2007 Lactococcus lactis subsp. cremoris SK11 transposase YP_811601.1 1901793 R 272622 CDS YP_811602.1 116512695 4432836 complement(1902993..1903574) 1 NC_008527.1 hypothetical protein 1903574 4432836 LACR_2008 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811602.1 1902993 R 272622 CDS YP_811603.1 116512696 4432837 complement(1903656..1906487) 1 NC_008527.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1906487 uvrA 4432837 uvrA Lactococcus lactis subsp. cremoris SK11 excinuclease ABC subunit A YP_811603.1 1903656 R 272622 CDS YP_811604.1 116512697 4432838 complement(1906632..1907270) 1 NC_008527.1 hypothetical protein 1907270 4432838 LACR_2010 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811604.1 1906632 R 272622 CDS YP_811605.1 116512698 4432839 1907377..1907673 1 NC_008527.1 endonuclease 1907673 4432839 LACR_2011 Lactococcus lactis subsp. cremoris SK11 endonuclease YP_811605.1 1907377 D 272622 CDS YP_811606.1 116512699 4432840 complement(1907706..1909055) 1 NC_008527.1 gamma-aminobutyrate permease related permease 1909055 4432840 LACR_2012 Lactococcus lactis subsp. cremoris SK11 gamma-aminobutyrate permease related permease YP_811606.1 1907706 R 272622 CDS YP_811607.1 116512700 4432841 complement(1909456..1910373) 1 NC_008527.1 dehydrogenase related protein 1910373 4432841 LACR_2013 Lactococcus lactis subsp. cremoris SK11 dehydrogenase related protein YP_811607.1 1909456 R 272622 CDS YP_811608.1 116512701 4432842 complement(1910404..1911039) 1 NC_008527.1 thiamine pyrophosphokinase 1911039 4432842 LACR_2014 Lactococcus lactis subsp. cremoris SK11 thiamine pyrophosphokinase YP_811608.1 1910404 R 272622 CDS YP_811609.1 116512702 4432843 complement(1911036..1911383) 1 NC_008527.1 hypothetical protein 1911383 4432843 LACR_2015 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811609.1 1911036 R 272622 CDS YP_811610.1 116512703 4432844 complement(1911415..1911810) 1 NC_008527.1 hypothetical protein 1911810 4432844 LACR_2016 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811610.1 1911415 R 272622 CDS YP_811611.1 116512704 4432845 1912059..1912379 1 NC_008527.1 hypothetical protein 1912379 4432845 LACR_2017 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811611.1 1912059 D 272622 CDS YP_811612.1 116512705 4432846 1912452..1913342 1 NC_008527.1 transposase 1913342 4432846 LACR_2018 Lactococcus lactis subsp. cremoris SK11 transposase YP_811612.1 1912452 D 272622 CDS YP_811613.1 116512706 4432847 1913411..1913584 1 NC_008527.1 hypothetical protein 1913584 4432847 LACR_2019 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811613.1 1913411 D 272622 CDS YP_811614.1 116512707 4432848 complement(1913625..1914968) 1 NC_008527.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1914968 asnC 4432848 asnC Lactococcus lactis subsp. cremoris SK11 asparaginyl-tRNA synthetase YP_811614.1 1913625 R 272622 CDS YP_811615.1 116512708 4432849 complement(1915016..1915327) 1 NC_008527.1 hypothetical protein 1915327 4432849 LACR_2021 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811615.1 1915016 R 272622 CDS YP_811616.1 116512709 4433751 complement(1915320..1916501) 1 NC_008527.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1916501 4433751 LACR_2022 Lactococcus lactis subsp. cremoris SK11 aspartate aminotransferase YP_811616.1 1915320 R 272622 CDS YP_811617.1 116512710 4433752 complement(1916498..1916941) 1 NC_008527.1 hypothetical protein 1916941 4433752 LACR_2023 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811617.1 1916498 R 272622 CDS YP_811618.1 116512711 4433753 complement(1917077..1919452) 1 NC_008527.1 Rad3-related DNA helicase 1919452 4433753 LACR_2024 Lactococcus lactis subsp. cremoris SK11 Rad3-related DNA helicase YP_811618.1 1917077 R 272622 CDS YP_811619.1 116512712 4433754 1919700..1920137 1 NC_008527.1 universal stress protein UspA-like nucleotide-binding protein 1920137 4433754 LACR_2025 Lactococcus lactis subsp. cremoris SK11 universal stress protein UspA-like nucleotide-binding protein YP_811619.1 1919700 D 272622 CDS YP_811620.1 116512713 4433755 complement(1920309..1922111) 1 NC_008527.1 ABC-type oligopeptide transport system, periplasmic component 1922111 4433755 LACR_2026 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, periplasmic component YP_811620.1 1920309 R 272622 CDS YP_811621.1 116512714 4433756 complement(1922224..1923108) 1 NC_008527.1 ABC-type dipeptide/oligopeptide/nickel transport system, permease component 1923108 4433756 LACR_2027 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, permease component YP_811621.1 1922224 R 272622 CDS YP_811622.1 116512715 4433757 complement(1923118..1924077) 1 NC_008527.1 ABC-type dipeptide/oligopeptide/nickel transport system, permease component 1924077 4433757 LACR_2028 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, permease component YP_811622.1 1923118 R 272622 CDS YP_811623.1 116512716 4433758 complement(1924058..1925017) 1 NC_008527.1 ABC-type oligopeptide transport system, ATPase component 1925017 4433758 LACR_2029 Lactococcus lactis subsp. cremoris SK11 ABC-type oligopeptide transport system, ATPase component YP_811623.1 1924058 R 272622 CDS YP_811624.1 116512717 4433759 complement(1925014..1926030) 1 NC_008527.1 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component 1926030 4433759 LACR_2030 Lactococcus lactis subsp. cremoris SK11 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_811624.1 1925014 R 272622 CDS YP_811625.1 116512718 4433760 complement(1926300..1926605) 1 NC_008527.1 50S ribosomal protein L20 1926605 4433760 LACR_2031 Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L20 YP_811625.1 1926300 R 272622 CDS YP_811626.1 116512719 4433761 complement(1926795..1926995) 1 NC_008527.1 50S ribosomal protein L35 1926995 rpmI 4433761 rpmI Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L35 YP_811626.1 1926795 R 272622 CDS YP_811627.1 116512720 4433762 complement(1927123..1927773) 1 NC_008527.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1927773 infC 4433762 infC Lactococcus lactis subsp. cremoris SK11 translation initiation factor IF-3 YP_811627.1 1927123 R 272622 CDS YP_811628.1 116512721 4433763 1928080..1928208 1 NC_008527.1 hypothetical protein 1928208 4433763 LACR_2034 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811628.1 1928080 D 272622 CDS YP_811629.1 116512722 4433764 complement(1928241..1929131) 1 NC_008527.1 transposase 1929131 4433764 LACR_2035 Lactococcus lactis subsp. cremoris SK11 transposase YP_811629.1 1928241 R 272622 CDS YP_811630.1 116512723 4433765 1929247..1929339 1 NC_008527.1 hypothetical protein 1929339 4433765 LACR_2036 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811630.1 1929247 D 272622 CDS YP_811631.1 116512724 4433767 complement(1929823..1930509) 1 NC_008527.1 HAD superfamily hydrolase 1930509 4433767 LACR_2038 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_811631.1 1929823 R 272622 CDS YP_811632.1 116512725 4433768 complement(1930694..1932571) 1 NC_008527.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1932571 4433768 LACR_2039 Lactococcus lactis subsp. cremoris SK11 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_811632.1 1930694 R 272622 CDS YP_811633.1 116512726 4432414 complement(1932955..1933518) 1 NC_008527.1 hypothetical protein 1933518 4432414 LACR_2040 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811633.1 1932955 R 272622 CDS YP_811634.1 116512727 4432415 complement(1933651..1934001) 1 NC_008527.1 hypothetical protein 1934001 4432415 LACR_2041 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811634.1 1933651 R 272622 CDS YP_811635.1 116512728 4432416 complement(1934134..1934535) 1 NC_008527.1 ribonuclease III family protein 1934535 4432416 LACR_2042 Lactococcus lactis subsp. cremoris SK11 ribonuclease III family protein YP_811635.1 1934134 R 272622 CDS YP_811636.1 116512729 4432417 complement(1934528..1935874) 1 NC_008527.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1935874 cysS 4432417 cysS Lactococcus lactis subsp. cremoris SK11 cysteinyl-tRNA synthetase YP_811636.1 1934528 R 272622 CDS YP_811637.1 116512730 4432418 complement(1935887..1936480) 1 NC_008527.1 hypothetical protein 1936480 4432418 LACR_2044 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811637.1 1935887 R 272622 CDS YP_811638.1 116512731 4432419 complement(1936494..1937093) 1 NC_008527.1 serine O-acetyltransferase 1937093 4432419 LACR_2045 Lactococcus lactis subsp. cremoris SK11 serine O-acetyltransferase YP_811638.1 1936494 R 272622 CDS YP_811639.1 116512732 4432420 complement(1937199..1937969) 1 NC_008527.1 hypothetical protein 1937969 4432420 LACR_2046 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811639.1 1937199 R 272622 CDS YP_811640.1 116512733 4432421 complement(1938238..1940547) 1 NC_008527.1 polynucleotide phosphorylase/polyadenylase 1940547 4432421 LACR_2047 Lactococcus lactis subsp. cremoris SK11 polynucleotide phosphorylase/polyadenylase YP_811640.1 1938238 R 272622 CDS YP_811641.1 116512734 4432422 complement(1940828..1942012) 1 NC_008527.1 hypothetical protein 1942012 4432422 LACR_2048 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811641.1 1940828 R 272622 CDS YP_811642.1 116512735 4432423 1942338..1943303 1 NC_008527.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1943303 4432423 LACR_2049 Lactococcus lactis subsp. cremoris SK11 ribose-phosphate pyrophosphokinase YP_811642.1 1942338 D 272622 CDS YP_811643.1 116512736 4432424 complement(1943408..1943839) 1 NC_008527.1 universal stress protein UspA-like nucleotide-binding protein 1943839 4432424 LACR_2050 Lactococcus lactis subsp. cremoris SK11 universal stress protein UspA-like nucleotide-binding protein YP_811643.1 1943408 R 272622 CDS YP_811644.1 116512737 4432425 complement(1944027..1944245) 1 NC_008527.1 hypothetical protein 1944245 4432425 LACR_2051 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811644.1 1944027 R 272622 CDS YP_811645.1 116512738 4432427 1945289..1945627 1 NC_008527.1 hypothetical protein 1945627 4432427 LACR_2053 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811645.1 1945289 D 272622 CDS YP_811646.1 116512739 4432428 complement(1945722..1946909) 1 NC_008527.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1946909 4432428 LACR_2054 Lactococcus lactis subsp. cremoris SK11 elongation factor Tu YP_811646.1 1945722 R 272622 CDS YP_811647.1 116512740 4432429 1947153..1947335 1 NC_008527.1 hypothetical protein 1947335 4432429 LACR_2055 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811647.1 1947153 D 272622 CDS YP_811648.1 116512741 4432430 complement(1947570..1950368) 1 NC_008527.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1950368 ileS 4432430 ileS Lactococcus lactis subsp. cremoris SK11 isoleucyl-tRNA synthetase YP_811648.1 1947570 R 272622 CDS YP_811649.1 116512742 4432815 complement(1950818..1951753) 1 NC_008527.1 cell division initiation protein 1951753 4432815 LACR_2057 Lactococcus lactis subsp. cremoris SK11 cell division initiation protein YP_811649.1 1950818 R 272622 CDS YP_811650.1 116512743 4432816 complement(1951810..1952601) 1 NC_008527.1 cell division protein 1952601 4432816 LACR_2058 Lactococcus lactis subsp. cremoris SK11 cell division protein YP_811650.1 1951810 R 272622 CDS YP_811651.1 116512744 4432817 complement(1952598..1952873) 1 NC_008527.1 hypothetical protein 1952873 4432817 LACR_2059 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811651.1 1952598 R 272622 CDS YP_811652.1 116512745 4432818 complement(1952873..1953463) 1 NC_008527.1 cell division protein 1953463 4432818 LACR_2060 Lactococcus lactis subsp. cremoris SK11 cell division protein YP_811652.1 1952873 R 272622 CDS YP_811653.1 116512746 4432819 complement(1953497..1954174) 1 NC_008527.1 TIM-barrel fold family protein 1954174 4432819 LACR_2061 Lactococcus lactis subsp. cremoris SK11 TIM-barrel fold family protein YP_811653.1 1953497 R 272622 CDS YP_811654.1 116512747 4432820 complement(1954178..1955431) 1 NC_008527.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1955431 4432820 LACR_2062 Lactococcus lactis subsp. cremoris SK11 cell division protein FtsZ YP_811654.1 1954178 R 272622 CDS YP_811655.1 116512748 4432821 complement(1955461..1956831) 1 NC_008527.1 cell division protein FtsA 1956831 4432821 LACR_2063 Lactococcus lactis subsp. cremoris SK11 cell division protein FtsA YP_811655.1 1955461 R 272622 CDS YP_811656.1 116512749 4432822 complement(1956994..1957863) 1 NC_008527.1 hypothetical protein 1957863 4432822 LACR_2064 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811656.1 1956994 R 272622 CDS YP_811657.1 116512750 4432823 complement(1957980..1958708) 1 NC_008527.1 rRNA methylase 1958708 4432823 LACR_2065 Lactococcus lactis subsp. cremoris SK11 rRNA methylase YP_811657.1 1957980 R 272622 CDS YP_811658.1 116512751 4432824 complement(1958901..1959791) 1 NC_008527.1 transposase 1959791 4432824 LACR_2066 Lactococcus lactis subsp. cremoris SK11 transposase YP_811658.1 1958901 R 272622 CDS YP_811659.1 116512752 4432825 complement(1959868..1960980) 1 NC_008527.1 glycine/D-amino acid oxidase (deaminating) 1960980 4432825 LACR_2067 Lactococcus lactis subsp. cremoris SK11 glycine/D-amino acid oxidase (deaminating) YP_811659.1 1959868 R 272622 CDS YP_811660.1 116512753 4432826 complement(1961118..1961912) 1 NC_008527.1 aldo/keto reductase 1961912 4432826 LACR_2068 Lactococcus lactis subsp. cremoris SK11 aldo/keto reductase YP_811660.1 1961118 R 272622 CDS YP_811661.1 116512754 4432827 complement(1961975..1963297) 1 NC_008527.1 major facilitator superfamily permease 1963297 4432827 LACR_2069 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_811661.1 1961975 R 272622 CDS YP_811662.1 116512755 4432830 complement(1964470..1964709) 1 NC_008527.1 transcriptional regulator 1964709 4432830 LACR_2072 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811662.1 1964470 R 272622 CDS YP_811663.1 116512756 4432831 complement(1964789..1966099) 1 NC_008527.1 aminopeptidase C 1966099 4432831 LACR_2073 Lactococcus lactis subsp. cremoris SK11 aminopeptidase C YP_811663.1 1964789 R 272622 CDS YP_811664.1 116512757 4432832 complement(1966228..1966902) 1 NC_008527.1 HD superfamily hydrolase 1966902 4432832 LACR_2074 Lactococcus lactis subsp. cremoris SK11 HD superfamily hydrolase YP_811664.1 1966228 R 272622 CDS YP_811665.1 116512758 4433680 complement(1966920..1967423) 1 NC_008527.1 hypothetical protein 1967423 4433680 LACR_2075 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811665.1 1966920 R 272622 CDS YP_811666.1 116512759 4433681 complement(1967560..1968240) 1 NC_008527.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1968240 4433681 LACR_2076 Lactococcus lactis subsp. cremoris SK11 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_811666.1 1967560 R 272622 CDS YP_811667.1 116512760 4433682 complement(1968268..1968546) 1 NC_008527.1 hypothetical protein 1968546 4433682 LACR_2077 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811667.1 1968268 R 272622 CDS YP_811668.1 116512761 4433683 complement(1968539..1969123) 1 NC_008527.1 NUDIX family hydrolase 1969123 4433683 LACR_2078 Lactococcus lactis subsp. cremoris SK11 NUDIX family hydrolase YP_811668.1 1968539 R 272622 CDS YP_811669.1 116512762 4433684 complement(1969225..1970601) 1 NC_008527.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 1970601 glmU 4433684 glmU Lactococcus lactis subsp. cremoris SK11 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_811669.1 1969225 R 272622 CDS YP_811670.1 116512763 4433685 1970824..1971615 1 NC_008527.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1971615 4433685 LACR_2080 Lactococcus lactis subsp. cremoris SK11 pyrroline-5-carboxylate reductase YP_811670.1 1970824 D 272622 CDS YP_811671.1 116512764 4433686 complement(1971699..1971968) 1 NC_008527.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1971968 rpsO 4433686 rpsO Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S15 YP_811671.1 1971699 R 272622 CDS YP_811672.1 116512765 4433687 complement(1972139..1974016) 1 NC_008527.1 serine/threonine protein kinase 1974016 4433687 LACR_2082 Lactococcus lactis subsp. cremoris SK11 serine/threonine protein kinase YP_811672.1 1972139 R 272622 CDS YP_811673.1 116512766 4433688 complement(1974016..1974792) 1 NC_008527.1 Serine/threonine protein phosphatase 1974792 4433688 LACR_2083 Lactococcus lactis subsp. cremoris SK11 Serine/threonine protein phosphatase YP_811673.1 1974016 R 272622 CDS YP_811674.1 116512767 4433689 complement(1974915..1976189) 1 NC_008527.1 tRNA and rRNA cytosine-C5-methylase 1976189 4433689 LACR_2084 Lactococcus lactis subsp. cremoris SK11 tRNA and rRNA cytosine-C5-methylase YP_811674.1 1974915 R 272622 CDS YP_811675.1 116512768 4433690 complement(1976477..1977103) 1 NC_008527.1 hypothetical protein 1977103 4433690 LACR_2085 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811675.1 1976477 R 272622 CDS YP_811676.1 116512769 4433691 complement(1977214..1978146) 1 NC_008527.1 glycosyltransferase 1978146 4433691 LACR_2086 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_811676.1 1977214 R 272622 CDS YP_811677.1 116512770 4433692 complement(1978070..1979671) 1 NC_008527.1 hypothetical protein 1979671 4433692 LACR_2087 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811677.1 1978070 R 272622 CDS YP_811678.1 116512771 4433693 complement(1979811..1980878) 1 NC_008527.1 cell wall-associated hydrolase 1980878 4433693 LACR_2088 Lactococcus lactis subsp. cremoris SK11 cell wall-associated hydrolase YP_811678.1 1979811 R 272622 CDS YP_811679.1 116512772 4433694 complement(1980891..1981262) 1 NC_008527.1 hypothetical protein 1981262 4433694 LACR_2089 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811679.1 1980891 R 272622 CDS YP_811680.1 116512773 4433696 complement(1982737..1982874) 1 NC_008527.1 hypothetical protein 1982874 4433696 LACR_2091 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811680.1 1982737 R 272622 CDS YP_811681.1 116512774 4433142 complement(1985384..1985749) 1 NC_008527.1 hypothetical protein 1985749 4433142 LACR_2093 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811681.1 1985384 R 272622 CDS YP_811682.1 116512775 4433143 complement(1985761..1990461) 1 NC_008527.1 SLT domain-containing protein 1990461 4433143 LACR_2094 Lactococcus lactis subsp. cremoris SK11 SLT domain-containing protein YP_811682.1 1985761 R 272622 CDS YP_811683.1 116512776 4433144 complement(1990493..1990864) 1 NC_008527.1 hypothetical protein 1990864 4433144 LACR_2095 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811683.1 1990493 R 272622 CDS YP_811684.1 116512777 4433145 complement(1990888..1991298) 1 NC_008527.1 hypothetical protein 1991298 4433145 LACR_2096 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811684.1 1990888 R 272622 CDS YP_811685.1 116512778 4433146 complement(1991372..1991785) 1 NC_008527.1 hypothetical protein 1991785 4433146 LACR_2097 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811685.1 1991372 R 272622 CDS YP_811686.1 116512779 4433147 complement(1991798..1992160) 1 NC_008527.1 hypothetical protein 1992160 4433147 LACR_2098 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811686.1 1991798 R 272622 CDS YP_811687.1 116512780 4433148 complement(1992160..1992708) 1 NC_008527.1 hypothetical protein 1992708 4433148 LACR_2099 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811687.1 1992160 R 272622 CDS YP_811688.1 116512781 4433149 complement(1992692..1993009) 1 NC_008527.1 hypothetical protein 1993009 4433149 LACR_2100 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811688.1 1992692 R 272622 CDS YP_811689.1 116512782 4433150 complement(1993026..1993352) 1 NC_008527.1 hypothetical protein 1993352 4433150 LACR_2101 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811689.1 1993026 R 272622 CDS YP_811690.1 116512783 4433151 complement(1993373..1994491) 1 NC_008527.1 Ig-like domain-containing protein 1994491 4433151 LACR_2102 Lactococcus lactis subsp. cremoris SK11 Ig-like domain-containing protein YP_811690.1 1993373 R 272622 CDS YP_811691.1 116512784 4433152 complement(1994503..1995240) 1 NC_008527.1 hypothetical protein 1995240 4433152 LACR_2103 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811691.1 1994503 R 272622 CDS YP_811692.1 116512785 4433153 complement(1995324..1996430) 1 NC_008527.1 NAD+--asparagine ADP-ribosyltransferase 1996430 4433153 LACR_2104 Lactococcus lactis subsp. cremoris SK11 NAD+--asparagine ADP-ribosyltransferase YP_811692.1 1995324 R 272622 CDS YP_811693.1 116512786 4433154 complement(1996436..1996723) 1 NC_008527.1 hypothetical protein 1996723 4433154 LACR_2105 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811693.1 1996436 R 272622 CDS YP_811694.1 116512787 4433155 complement(1996720..1996962) 1 NC_008527.1 hypothetical protein 1996962 4433155 LACR_2106 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811694.1 1996720 R 272622 CDS YP_811695.1 116512788 4433156 complement(1996992..1997156) 1 NC_008527.1 hypothetical protein 1997156 4433156 LACR_2107 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811695.1 1996992 R 272622 CDS YP_811696.1 116512789 4433157 complement(1997113..1998621) 1 NC_008527.1 hypothetical protein 1998621 4433157 LACR_2108 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811696.1 1997113 R 272622 CDS YP_811697.1 116512790 4433158 complement(1998630..1999865) 1 NC_008527.1 Phage terminase large subunit 1999865 4433158 LACR_2109 Lactococcus lactis subsp. cremoris SK11 Phage terminase large subunit YP_811697.1 1998630 R 272622 CDS YP_811698.1 116512791 4433072 complement(1999855..2000367) 1 NC_008527.1 Phage terminase, small subunit 2000367 4433072 LACR_2110 Lactococcus lactis subsp. cremoris SK11 Phage terminase, small subunit YP_811698.1 1999855 R 272622 CDS YP_811699.1 116512792 4433073 complement(2000663..2001088) 1 NC_008527.1 hypothetical protein 2001088 4433073 LACR_2111 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811699.1 2000663 R 272622 CDS YP_811700.1 116512793 4433074 complement(2001165..2001473) 1 NC_008527.1 hypothetical protein 2001473 4433074 LACR_2112 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811700.1 2001165 R 272622 CDS YP_811701.1 116512794 4433075 complement(2001806..2001991) 1 NC_008527.1 hypothetical protein 2001991 4433075 LACR_2113 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811701.1 2001806 R 272622 CDS YP_811702.1 116512795 4433076 complement(2001999..2002193) 1 NC_008527.1 hypothetical protein 2002193 4433076 LACR_2114 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811702.1 2001999 R 272622 CDS YP_811703.1 116512796 4433077 complement(2002190..2002432) 1 NC_008527.1 hypothetical protein 2002432 4433077 LACR_2115 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811703.1 2002190 R 272622 CDS YP_811704.1 116512797 4433078 complement(2002483..2003169) 1 NC_008527.1 hypothetical protein 2003169 4433078 LACR_2116 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811704.1 2002483 R 272622 CDS YP_811705.1 116512798 4433079 complement(2003156..2003467) 1 NC_008527.1 hypothetical protein 2003467 4433079 LACR_2117 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811705.1 2003156 R 272622 CDS YP_811706.1 116512799 4433080 complement(2003467..2003886) 1 NC_008527.1 deoxyuridine 5'-triphosphate nucleotidohydrolase 2003886 4433080 LACR_2118 Lactococcus lactis subsp. cremoris SK11 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_811706.1 2003467 R 272622 CDS YP_811707.1 116512800 4433081 complement(2003883..2004239) 1 NC_008527.1 hypothetical protein 2004239 4433081 LACR_2119 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811707.1 2003883 R 272622 CDS YP_811708.1 116512801 4433082 complement(2004236..2004757) 1 NC_008527.1 hypothetical protein 2004757 4433082 LACR_2120 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811708.1 2004236 R 272622 CDS YP_811709.1 116512802 4433083 complement(2004750..2004956) 1 NC_008527.1 hypothetical protein 2004956 4433083 LACR_2121 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811709.1 2004750 R 272622 CDS YP_811710.1 116512803 4433084 complement(2004970..2005494) 1 NC_008527.1 hypothetical protein 2005494 4433084 LACR_2122 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811710.1 2004970 R 272622 CDS YP_811711.1 116512804 4433085 complement(2005601..2005840) 1 NC_008527.1 hypothetical protein 2005840 4433085 LACR_2123 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811711.1 2005601 R 272622 CDS YP_811712.1 116512805 4433087 complement(2006007..2006261) 1 NC_008527.1 hypothetical protein 2006261 4433087 LACR_2125 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811712.1 2006007 R 272622 CDS YP_811713.1 116512806 4433088 complement(2006251..2006472) 1 NC_008527.1 hypothetical protein 2006472 4433088 LACR_2126 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811713.1 2006251 R 272622 CDS YP_811714.1 116512807 4434389 complement(2006665..2007255) 1 NC_008527.1 hypothetical protein 2007255 4434389 LACR_2127 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811714.1 2006665 R 272622 CDS YP_811715.1 116512808 4434390 complement(2007398..2007823) 1 NC_008527.1 single-stranded DNA-binding protein 2007823 4434390 LACR_2128 Lactococcus lactis subsp. cremoris SK11 single-stranded DNA-binding protein YP_811715.1 2007398 R 272622 CDS YP_811716.1 116512809 4434391 complement(2007816..2008574) 1 NC_008527.1 hypothetical protein 2008574 4434391 LACR_2129 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811716.1 2007816 R 272622 CDS YP_811717.1 116512810 4434392 complement(2008583..2008978) 1 NC_008527.1 hypothetical protein 2008978 4434392 LACR_2130 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811717.1 2008583 R 272622 CDS YP_811718.1 116512811 4434393 complement(2009077..2009313) 1 NC_008527.1 hypothetical protein 2009313 4434393 LACR_2131 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811718.1 2009077 R 272622 CDS YP_811719.1 116512812 4434394 2009419..2009775 1 NC_008527.1 hypothetical protein 2009775 4434394 LACR_2132 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811719.1 2009419 D 272622 CDS YP_811720.1 116512813 4434395 complement(2009763..2010197) 1 NC_008527.1 hypothetical protein 2010197 4434395 LACR_2133 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811720.1 2009763 R 272622 CDS YP_811721.1 116512814 4434396 complement(2010291..2010560) 1 NC_008527.1 hypothetical protein 2010560 4434396 LACR_2134 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811721.1 2010291 R 272622 CDS YP_811722.1 116512815 4434397 complement(2010573..2011355) 1 NC_008527.1 phage-encoded protein 2011355 4434397 LACR_2135 Lactococcus lactis subsp. cremoris SK11 phage-encoded protein YP_811722.1 2010573 R 272622 CDS YP_811723.1 116512816 4434398 complement(2011368..2011607) 1 NC_008527.1 hypothetical protein 2011607 4434398 LACR_2136 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811723.1 2011368 R 272622 CDS YP_811724.1 116512817 4434399 2011705..2012214 1 NC_008527.1 hypothetical protein 2012214 4434399 LACR_2137 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811724.1 2011705 D 272622 CDS YP_811725.1 116512818 4434400 complement(2012200..2012472) 1 NC_008527.1 hypothetical protein 2012472 4434400 LACR_2138 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811725.1 2012200 R 272622 CDS YP_811726.1 116512819 4434401 2012539..2012649 1 NC_008527.1 hypothetical protein 2012649 4434401 LACR_2139 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811726.1 2012539 D 272622 CDS YP_811727.1 116512820 4434402 complement(2012627..2012821) 1 NC_008527.1 hypothetical protein 2012821 4434402 LACR_2140 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811727.1 2012627 R 272622 CDS YP_811728.1 116512821 4434403 complement(2012832..2013026) 1 NC_008527.1 hypothetical protein 2013026 4434403 LACR_2141 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811728.1 2012832 R 272622 CDS YP_811729.1 116512822 4434404 2013289..2013816 1 NC_008527.1 XRE family transcriptional regulator 2013816 4434404 LACR_2142 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_811729.1 2013289 D 272622 CDS YP_811730.1 116512823 4434405 2013822..2014256 1 NC_008527.1 Zn peptidase 2014256 4434405 LACR_2143 Lactococcus lactis subsp. cremoris SK11 Zn peptidase YP_811730.1 2013822 D 272622 CDS YP_811731.1 116512824 4434406 2014270..2014605 1 NC_008527.1 hypothetical protein 2014605 4434406 LACR_2144 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811731.1 2014270 D 272622 CDS YP_811732.1 116512825 4433980 2014672..2015853 1 NC_008527.1 integrase 2015853 4433980 LACR_2145 Lactococcus lactis subsp. cremoris SK11 integrase YP_811732.1 2014672 D 272622 CDS YP_811733.1 116512826 4433981 complement(2016148..2016654) 1 NC_008527.1 hypothetical protein 2016654 4433981 LACR_2146 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811733.1 2016148 R 272622 CDS YP_811734.1 116512827 4433982 complement(2016664..2016852) 1 NC_008527.1 hypothetical protein 2016852 4433982 LACR_2147 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811734.1 2016664 R 272622 CDS YP_811735.1 116512828 4433983 complement(2016863..2017423) 1 NC_008527.1 hypothetical protein 2017423 4433983 LACR_2148 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811735.1 2016863 R 272622 CDS YP_811736.1 116512829 4433984 complement(2017451..2017693) 1 NC_008527.1 hypothetical protein 2017693 4433984 LACR_2149 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811736.1 2017451 R 272622 CDS YP_811737.1 116512830 4433985 complement(2017929..2018900) 1 NC_008527.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 2018900 fmt 4433985 fmt Lactococcus lactis subsp. cremoris SK11 methionyl-tRNA formyltransferase YP_811737.1 2017929 R 272622 CDS YP_811738.1 116512831 4433986 complement(2018897..2019217) 1 NC_008527.1 hypothetical protein 2019217 4433986 LACR_2151 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811738.1 2018897 R 272622 CDS YP_811739.1 116512832 4433988 complement(2019326..2019847) 1 NC_008527.1 NUDIX family hydrolase 2019847 4433988 LACR_2153 Lactococcus lactis subsp. cremoris SK11 NUDIX family hydrolase YP_811739.1 2019326 R 272622 CDS YP_811740.1 116512833 4433989 complement(2019861..2020235) 1 NC_008527.1 hypothetical protein 2020235 4433989 LACR_2154 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811740.1 2019861 R 272622 CDS YP_811741.1 116512834 4433990 complement(2020357..2021472) 1 NC_008527.1 hypothetical protein 2021472 4433990 LACR_2155 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811741.1 2020357 R 272622 CDS YP_811742.1 116512835 4433991 complement(2021496..2023841) 1 NC_008527.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 2023841 4433991 LACR_2156 Lactococcus lactis subsp. cremoris SK11 primosome assembly protein PriA YP_811742.1 2021496 R 272622 CDS YP_811743.1 116512836 4433992 complement(2024018..2024371) 1 NC_008527.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2024371 4433992 LACR_2157 Lactococcus lactis subsp. cremoris SK11 DNA-directed RNA polymerase subunit omega YP_811743.1 2024018 R 272622 CDS YP_811744.1 116512837 4433993 complement(2024440..2025057) 1 NC_008527.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2025057 gmk 4433993 gmk Lactococcus lactis subsp. cremoris SK11 guanylate kinase YP_811744.1 2024440 R 272622 CDS YP_811745.1 116512838 4433994 complement(2025206..2026801) 1 NC_008527.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 2026801 4433994 LACR_2159 Lactococcus lactis subsp. cremoris SK11 phosphodiesterase YP_811745.1 2025206 R 272622 CDS YP_811746.1 116512839 4433995 complement(2027035..2027748) 1 NC_008527.1 putative 6-phosphogluconolactonase 2027748 4433995 LACR_2160 Lactococcus lactis subsp. cremoris SK11 putative 6-phosphogluconolactonase YP_811746.1 2027035 R 272622 CDS YP_811747.1 116512840 4433996 complement(2027852..2029051) 1 NC_008527.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2029051 4433996 LACR_2161 Lactococcus lactis subsp. cremoris SK11 S-adenosylmethionine synthetase YP_811747.1 2027852 R 272622 CDS YP_811748.1 116512841 4434205 complement(2029544..2030737) 1 NC_008527.1 cyclopropane-fatty-acyl-phospholipid synthase 2030737 4434205 LACR_2162 Lactococcus lactis subsp. cremoris SK11 cyclopropane-fatty-acyl-phospholipid synthase YP_811748.1 2029544 R 272622 CDS YP_811749.1 116512842 4434207 complement(2031773..2032237) 1 NC_008527.1 hypothetical protein 2032237 4434207 LACR_2164 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811749.1 2031773 R 272622 CDS YP_811750.1 116512843 4434209 complement(2032573..2033685) 1 NC_008527.1 hypothetical protein 2033685 4434209 LACR_2166 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811750.1 2032573 R 272622 CDS YP_811751.1 116512844 4434210 complement(2033896..2035620) 1 NC_008527.1 N-acetylmuramoyl-L-alanine amidase 2035620 4434210 LACR_2167 Lactococcus lactis subsp. cremoris SK11 N-acetylmuramoyl-L-alanine amidase YP_811751.1 2033896 R 272622 CDS YP_811752.1 116512845 4434211 complement(2035977..2036873) 1 NC_008527.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 2036873 4434211 LACR_2168 Lactococcus lactis subsp. cremoris SK11 fructose-bisphosphate aldolase YP_811752.1 2035977 R 272622 CDS YP_811753.1 116512846 4432065 complement(2042907..2043566) 1 NC_008527.1 hypothetical protein 2043566 4432065 LACR_2180 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811753.1 2042907 R 272622 CDS YP_811754.1 116512847 4432066 complement(2043672..2045612) 1 NC_008527.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2045612 thrS 4432066 thrS Lactococcus lactis subsp. cremoris SK11 threonyl-tRNA synthetase YP_811754.1 2043672 R 272622 CDS YP_811755.1 116512848 4432067 complement(2046305..2046622) 1 NC_008527.1 ATP-cone domain-containing protein 2046622 4432067 LACR_2182 Lactococcus lactis subsp. cremoris SK11 ATP-cone domain-containing protein YP_811755.1 2046305 R 272622 CDS YP_811756.1 116512849 4432068 complement(2046962..2047942) 1 NC_008527.1 manganese transporter NRAMP 2047942 4432068 LACR_2183 Lactococcus lactis subsp. cremoris SK11 manganese transporter NRAMP YP_811756.1 2046962 R 272622 CDS YP_811757.1 116512850 4432069 complement(2048048..2048656) 1 NC_008527.1 oxidoreductase 2048656 4432069 LACR_2184 Lactococcus lactis subsp. cremoris SK11 oxidoreductase YP_811757.1 2048048 R 272622 CDS YP_811758.1 116512851 4432070 complement(2048797..2049432) 1 NC_008527.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2049432 upp 4432070 upp Lactococcus lactis subsp. cremoris SK11 uracil phosphoribosyltransferase YP_811758.1 2048797 R 272622 CDS YP_811759.1 116512852 4432176 complement(2049634..2050773) 1 NC_008527.1 Na+/H+ antiporter 2050773 4432176 LACR_2186 Lactococcus lactis subsp. cremoris SK11 Na+/H+ antiporter YP_811759.1 2049634 R 272622 CDS YP_811760.1 116512853 4432177 complement(2051044..2052207) 1 NC_008527.1 bifunctional beta-cystathionase/maltose regulon repressor 2052207 4432177 LACR_2187 Lactococcus lactis subsp. cremoris SK11 bifunctional beta-cystathionase/maltose regulon repressor YP_811760.1 2051044 R 272622 CDS YP_811761.1 116512854 4432180 complement(2054699..2055256) 1 NC_008527.1 hypothetical protein 2055256 4432180 LACR_2190 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811761.1 2054699 R 272622 CDS YP_811762.1 116512855 4432181 complement(2055265..2056173) 1 NC_008527.1 hypothetical protein 2056173 4432181 LACR_2191 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811762.1 2055265 R 272622 CDS YP_811763.1 116512856 4432182 complement(2056308..2057177) 1 NC_008527.1 galactose mutarotase-like protein 2057177 4432182 LACR_2192 Lactococcus lactis subsp. cremoris SK11 galactose mutarotase-like protein YP_811763.1 2056308 R 272622 CDS YP_811764.1 116512857 4432183 complement(2057268..2058212) 1 NC_008527.1 HD-superfamily hydrolase 2058212 4432183 LACR_2193 Lactococcus lactis subsp. cremoris SK11 HD-superfamily hydrolase YP_811764.1 2057268 R 272622 CDS YP_811765.1 116512858 4432184 complement(2058285..2059583) 1 NC_008527.1 hypothetical protein 2059583 4432184 LACR_2194 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811765.1 2058285 R 272622 CDS YP_811766.1 116512859 4432185 complement(2059673..2060323) 1 NC_008527.1 ribulose-phosphate 3-epimerase 2060323 4432185 LACR_2195 Lactococcus lactis subsp. cremoris SK11 ribulose-phosphate 3-epimerase YP_811766.1 2059673 R 272622 CDS YP_811767.1 116512860 4432186 complement(2060398..2060655) 1 NC_008527.1 hypothetical protein 2060655 4432186 LACR_2196 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811767.1 2060398 R 272622 CDS YP_811768.1 116512861 4432187 complement(2060652..2060906) 1 NC_008527.1 hypothetical protein 2060906 4432187 LACR_2197 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811768.1 2060652 R 272622 CDS YP_811769.1 116512862 4432188 complement(2060878..2061801) 1 NC_008527.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 2061801 4432188 LACR_2198 Lactococcus lactis subsp. cremoris SK11 ribosome-associated GTPase YP_811769.1 2060878 R 272622 CDS YP_811770.1 116512863 4432189 complement(2061862..2062995) 1 NC_008527.1 aspartate protease family protein 2062995 4432189 LACR_2199 Lactococcus lactis subsp. cremoris SK11 aspartate protease family protein YP_811770.1 2061862 R 272622 CDS YP_811771.1 116512864 4432190 complement(2063236..2065629) 1 NC_008527.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2065629 pheT 4432190 pheT Lactococcus lactis subsp. cremoris SK11 phenylalanyl-tRNA synthetase subunit beta YP_811771.1 2063236 R 272622 CDS YP_811772.1 116512865 4432191 complement(2065740..2066777) 1 NC_008527.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2066777 pheS 4432191 pheS Lactococcus lactis subsp. cremoris SK11 phenylalanyl-tRNA synthetase subunit alpha YP_811772.1 2065740 R 272622 CDS YP_811773.1 116512866 4434187 complement(2067900..2068790) 1 NC_008527.1 transposase 2068790 4434187 LACR_2203 Lactococcus lactis subsp. cremoris SK11 transposase YP_811773.1 2067900 R 272622 CDS YP_811774.1 116512867 4434188 2069038..2069577 1 NC_008527.1 PadR family transcriptional regulator 2069577 4434188 LACR_2204 Lactococcus lactis subsp. cremoris SK11 PadR family transcriptional regulator YP_811774.1 2069038 D 272622 CDS YP_811775.1 116512868 4434189 2069745..2071223 1 NC_008527.1 glycosyl hydrolase family chitinase 2071223 4434189 LACR_2205 Lactococcus lactis subsp. cremoris SK11 glycosyl hydrolase family chitinase YP_811775.1 2069745 D 272622 CDS YP_811776.1 116512869 4434190 2071244..2071906 1 NC_008527.1 hypothetical protein 2071906 4434190 LACR_2206 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811776.1 2071244 D 272622 CDS YP_811777.1 116512870 4434191 complement(2071949..2073241) 1 NC_008527.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 2073241 4434191 LACR_2207 Lactococcus lactis subsp. cremoris SK11 adenylosuccinate synthetase YP_811777.1 2071949 R 272622 CDS YP_811778.1 116512871 4434192 complement(2073607..2074218) 1 NC_008527.1 permease, cadmium resistance protein 2074218 4434192 LACR_2208 Lactococcus lactis subsp. cremoris SK11 permease, cadmium resistance protein YP_811778.1 2073607 R 272622 CDS YP_811779.1 116512872 4434193 2074383..2075249 1 NC_008527.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2075249 hslO 4434193 hslO Lactococcus lactis subsp. cremoris SK11 Hsp33-like chaperonin YP_811779.1 2074383 D 272622 CDS YP_811780.1 116512873 4434195 2075904..2076758 1 NC_008527.1 transposase 2076758 4434195 LACR_2211 Lactococcus lactis subsp. cremoris SK11 transposase YP_811780.1 2075904 D 272622 CDS YP_811781.1 116512874 4434196 2077052..2077603 1 NC_008527.1 hypothetical protein 2077603 4434196 LACR_2212 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811781.1 2077052 D 272622 CDS YP_811782.1 116512875 4434197 2077549..2077800 1 NC_008527.1 hypothetical protein 2077800 4434197 LACR_2213 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811782.1 2077549 D 272622 CDS YP_811783.1 116512876 4434198 2077787..2078431 1 NC_008527.1 hypothetical protein 2078431 4434198 LACR_2214 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811783.1 2077787 D 272622 CDS YP_811784.1 116512877 4434199 2078428..2078544 1 NC_008527.1 hypothetical protein 2078544 4434199 LACR_2215 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811784.1 2078428 D 272622 CDS YP_811785.1 116512878 4434200 2078547..2078948 1 NC_008527.1 hypothetical protein 2078948 4434200 LACR_2216 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811785.1 2078547 D 272622 CDS YP_811786.1 116512879 4434201 2079226..2079402 1 NC_008527.1 hypothetical protein 2079402 4434201 LACR_2217 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811786.1 2079226 D 272622 CDS YP_811787.1 116512880 4434202 2079417..2079605 1 NC_008527.1 hypothetical protein 2079605 4434202 LACR_2218 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811787.1 2079417 D 272622 CDS YP_811788.1 116512881 4434203 2079796..2080281 1 NC_008527.1 hypothetical protein 2080281 4434203 LACR_2219 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811788.1 2079796 D 272622 CDS YP_811789.1 116512882 4434204 2080324..2080716 1 NC_008527.1 hypothetical protein 2080716 4434204 LACR_2220 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811789.1 2080324 D 272622 CDS YP_811790.1 116512883 4432712 2080828..2081832 1 NC_008527.1 tRNA-dihydrouridine synthase 2081832 4432712 LACR_2221 Lactococcus lactis subsp. cremoris SK11 tRNA-dihydrouridine synthase YP_811790.1 2080828 D 272622 CDS YP_811791.1 116512884 4432713 2082148..2082378 1 NC_008527.1 hypothetical protein 2082378 4432713 LACR_2222 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811791.1 2082148 D 272622 CDS YP_811792.1 116512885 4432714 complement(2082418..2083302) 1 NC_008527.1 hypothetical protein 2083302 4432714 LACR_2223 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811792.1 2082418 R 272622 CDS YP_811793.1 116512886 4432715 complement(2083452..2084327) 1 NC_008527.1 hypothetical protein 2084327 4432715 LACR_2224 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811793.1 2083452 R 272622 CDS YP_811794.1 116512887 4432716 complement(2084431..2085360) 1 NC_008527.1 hypothetical protein 2085360 4432716 LACR_2225 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811794.1 2084431 R 272622 CDS YP_811795.1 116512888 4432717 complement(2085341..2087113) 1 NC_008527.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2087113 aspS 4432717 aspS Lactococcus lactis subsp. cremoris SK11 aspartyl-tRNA synthetase YP_811795.1 2085341 R 272622 CDS YP_811796.1 116512889 4432718 complement(2087177..2087545) 1 NC_008527.1 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 2087545 4432718 LACR_2227 Lactococcus lactis subsp. cremoris SK11 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases YP_811796.1 2087177 R 272622 CDS YP_811797.1 116512890 4432719 complement(2087571..2088863) 1 NC_008527.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2088863 hisS 4432719 hisS Lactococcus lactis subsp. cremoris SK11 histidyl-tRNA synthetase YP_811797.1 2087571 R 272622 CDS YP_811798.1 116512891 4432720 complement(2089188..2090249) 1 NC_008527.1 hypothetical protein 2090249 4432720 LACR_2229 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811798.1 2089188 R 272622 CDS YP_811799.1 116512892 4432721 complement(2090580..2090903) 1 NC_008527.1 hypothetical protein 2090903 4432721 LACR_2230 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811799.1 2090580 R 272622 CDS YP_811800.1 116512893 4432722 complement(2091613..2091936) 1 NC_008527.1 hypothetical protein 2091936 4432722 LACR_2231 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811800.1 2091613 R 272622 CDS YP_811801.1 116512894 4432723 complement(2092098..2092799) 1 NC_008527.1 hypothetical protein 2092799 4432723 LACR_2232 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811801.1 2092098 R 272622 CDS YP_811802.1 116512895 4432724 complement(2093038..2093610) 1 NC_008527.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2093610 4432724 LACR_2233 Lactococcus lactis subsp. cremoris SK11 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_811802.1 2093038 R 272622 CDS YP_811803.1 116512896 4432725 complement(2093652..2094548) 1 NC_008527.1 XRE-family DNA-binding domain-containing protein 2094548 4432725 LACR_2234 Lactococcus lactis subsp. cremoris SK11 XRE-family DNA-binding domain-containing protein YP_811803.1 2093652 R 272622 CDS YP_811804.1 116512897 4432726 complement(2094761..2096044) 1 NC_008527.1 Zn-dependent peptidase 2096044 4432726 LACR_2235 Lactococcus lactis subsp. cremoris SK11 Zn-dependent peptidase YP_811804.1 2094761 R 272622 CDS YP_811805.1 116512898 4432727 complement(2096034..2097320) 1 NC_008527.1 Zn-dependent peptidase 2097320 4432727 LACR_2236 Lactococcus lactis subsp. cremoris SK11 Zn-dependent peptidase YP_811805.1 2096034 R 272622 CDS YP_811806.1 116512899 4432728 2097518..2097880 1 NC_008527.1 hypothetical protein 2097880 4432728 LACR_2237 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811806.1 2097518 D 272622 CDS YP_811807.1 116512900 4433856 2097880..2098959 1 NC_008527.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2098959 recF 4433856 recF Lactococcus lactis subsp. cremoris SK11 recombination protein F YP_811807.1 2097880 D 272622 CDS YP_811808.1 116512901 4433857 complement(2099064..2099432) 1 NC_008527.1 gamma-carboxymuconolactone decarboxylase 2099432 4433857 LACR_2239 Lactococcus lactis subsp. cremoris SK11 gamma-carboxymuconolactone decarboxylase YP_811808.1 2099064 R 272622 CDS YP_811809.1 116512902 4433858 2099509..2099886 1 NC_008527.1 transcriptional regulator 2099886 4433858 LACR_2240 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811809.1 2099509 D 272622 CDS YP_811810.1 116512903 4433859 complement(2099903..2100859) 1 NC_008527.1 alpha/beta hydrolase superfamily protein 2100859 4433859 LACR_2241 Lactococcus lactis subsp. cremoris SK11 alpha/beta hydrolase superfamily protein YP_811810.1 2099903 R 272622 CDS YP_811811.1 116512904 4433860 complement(2100980..2101960) 1 NC_008527.1 UDP-galactose 4-epimerase 2101960 4433860 LACR_2242 Lactococcus lactis subsp. cremoris SK11 UDP-galactose 4-epimerase YP_811811.1 2100980 R 272622 CDS YP_811812.1 116512905 4433861 complement(2102077..2103558) 1 NC_008527.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 2103558 4433861 LACR_2243 Lactococcus lactis subsp. cremoris SK11 galactose-1-phosphate uridylyltransferase YP_811812.1 2102077 R 272622 CDS YP_811813.1 116512906 4433862 complement(2103731..2104930) 1 NC_008527.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 2104930 4433862 LACR_2244 Lactococcus lactis subsp. cremoris SK11 galactokinase YP_811813.1 2103731 R 272622 CDS YP_811814.1 116512907 4433863 complement(2104957..2105976) 1 NC_008527.1 aldose 1-epimerase 2105976 4433863 LACR_2245 Lactococcus lactis subsp. cremoris SK11 aldose 1-epimerase YP_811814.1 2104957 R 272622 CDS YP_811815.1 116512908 4433864 complement(2106182..2107570) 1 NC_008527.1 Na+/xyloside symporter related transporter 2107570 4433864 LACR_2246 Lactococcus lactis subsp. cremoris SK11 Na+/xyloside symporter related transporter YP_811815.1 2106182 R 272622 CDS YP_811816.1 116512909 4433865 complement(2107877..2108629) 1 NC_008527.1 transcriptional regulator 2108629 4433865 LACR_2247 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811816.1 2107877 R 272622 CDS YP_811817.1 116512910 4433866 2108764..2109768 1 NC_008527.1 aryl-alcohol dehydrogenase family oxidoreductase 2109768 4433866 LACR_2248 Lactococcus lactis subsp. cremoris SK11 aryl-alcohol dehydrogenase family oxidoreductase YP_811817.1 2108764 D 272622 CDS YP_811818.1 116512911 4433867 complement(2109836..2110975) 1 NC_008527.1 transcriptional regulator 2110975 4433867 LACR_2249 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811818.1 2109836 R 272622 CDS YP_811819.1 116512912 4433868 complement(2110962..2111939) 1 NC_008527.1 phosphoglycerate dehydrogenase-like protein 2111939 4433868 LACR_2250 Lactococcus lactis subsp. cremoris SK11 phosphoglycerate dehydrogenase-like protein YP_811819.1 2110962 R 272622 CDS YP_811820.1 116512913 4433869 complement(2112137..2113429) 1 NC_008527.1 collagenase-like protease 2113429 4433869 LACR_2251 Lactococcus lactis subsp. cremoris SK11 collagenase-like protease YP_811820.1 2112137 R 272622 CDS YP_811821.1 116512914 4433870 complement(2113714..2114679) 1 NC_008527.1 collagenase-like protease 2114679 4433870 LACR_2252 Lactococcus lactis subsp. cremoris SK11 collagenase-like protease YP_811821.1 2113714 R 272622 CDS YP_811822.1 116512915 4433871 2114857..2115138 1 NC_008527.1 hypothetical protein 2115138 4433871 LACR_2253 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811822.1 2114857 D 272622 CDS YP_811823.1 116512916 4433872 complement(2115168..2115989) 1 NC_008527.1 SAM-dependent methyltransferase 2115989 4433872 LACR_2254 Lactococcus lactis subsp. cremoris SK11 SAM-dependent methyltransferase YP_811823.1 2115168 R 272622 CDS YP_811824.1 116512917 4433873 complement(2116658..2117068) 1 NC_008527.1 hypothetical protein 2117068 4433873 LACR_2255 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811824.1 2116658 R 272622 CDS YP_811825.1 116512918 4432747 complement(2117065..2117508) 1 NC_008527.1 Phage terminase, small subunit 2117508 4432747 LACR_2256 Lactococcus lactis subsp. cremoris SK11 Phage terminase, small subunit YP_811825.1 2117065 R 272622 CDS YP_811826.1 116512919 4432748 complement(2117641..2118183) 1 NC_008527.1 hypothetical protein 2118183 4432748 LACR_2257 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811826.1 2117641 R 272622 CDS YP_811827.1 116512920 4432749 complement(2118400..2120028) 1 NC_008527.1 phage DNA polymerase 2120028 4432749 LACR_2258 Lactococcus lactis subsp. cremoris SK11 phage DNA polymerase YP_811827.1 2118400 R 272622 CDS YP_811828.1 116512921 4432750 complement(2120039..2120833) 1 NC_008527.1 hypothetical protein 2120833 4432750 LACR_2259 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811828.1 2120039 R 272622 CDS YP_811829.1 116512922 4432751 complement(2120830..2121165) 1 NC_008527.1 hypothetical protein 2121165 4432751 LACR_2260 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811829.1 2120830 R 272622 CDS YP_811830.1 116512923 4432752 complement(2121162..2121416) 1 NC_008527.1 hypothetical protein 2121416 4432752 LACR_2261 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811830.1 2121162 R 272622 CDS YP_811831.1 116512924 4432753 complement(2121413..2121652) 1 NC_008527.1 hypothetical protein 2121652 4432753 LACR_2262 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811831.1 2121413 R 272622 CDS YP_811832.1 116512925 4432754 complement(2121695..2121976) 1 NC_008527.1 hypothetical protein 2121976 4432754 LACR_2263 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811832.1 2121695 R 272622 CDS YP_811833.1 116512926 4432755 complement(2121973..2122224) 1 NC_008527.1 XRE family transcriptional regulator 2122224 4432755 LACR_2264 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_811833.1 2121973 R 272622 CDS YP_811834.1 116512927 4432756 complement(2122221..2122826) 1 NC_008527.1 hypothetical protein 2122826 4432756 LACR_2265 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811834.1 2122221 R 272622 CDS YP_811835.1 116512928 4432757 complement(2122831..2123025) 1 NC_008527.1 hypothetical protein 2123025 4432757 LACR_2266 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811835.1 2122831 R 272622 CDS YP_811836.1 116512929 4432758 complement(2123144..2123392) 1 NC_008527.1 Phage related anti-repressor protein 2123392 4432758 LACR_2267 Lactococcus lactis subsp. cremoris SK11 Phage related anti-repressor protein YP_811836.1 2123144 R 272622 CDS YP_811837.1 116512930 4432759 complement(2123396..2123593) 1 NC_008527.1 hypothetical protein 2123593 4432759 LACR_2268 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811837.1 2123396 R 272622 CDS YP_811838.1 116512931 4432760 2123852..2124235 1 NC_008527.1 XRE family transcriptional regulator 2124235 4432760 LACR_2269 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_811838.1 2123852 D 272622 CDS YP_811839.1 116512932 4432761 2124247..2124798 1 NC_008527.1 hypothetical protein 2124798 4432761 LACR_2270 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811839.1 2124247 D 272622 CDS YP_811840.1 116512933 4432762 2124812..2125006 1 NC_008527.1 hypothetical protein 2125006 4432762 LACR_2271 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811840.1 2124812 D 272622 CDS YP_811841.1 116512934 4432763 2125221..2125550 1 NC_008527.1 hypothetical protein 2125550 4432763 LACR_2272 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811841.1 2125221 D 272622 CDS YP_811842.1 116512935 4433269 2125666..2126976 1 NC_008527.1 hypothetical protein 2126976 4433269 LACR_2273 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811842.1 2125666 D 272622 CDS YP_811843.1 116512936 4433270 2127185..2127352 1 NC_008527.1 hypothetical protein 2127352 4433270 LACR_2274 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811843.1 2127185 D 272622 CDS YP_811844.1 116512937 4433271 2127625..2128806 1 NC_008527.1 integrase 2128806 4433271 LACR_2275 Lactococcus lactis subsp. cremoris SK11 integrase YP_811844.1 2127625 D 272622 CDS YP_811845.1 116512938 4433272 2129019..2129645 1 NC_008527.1 hypothetical protein 2129645 4433272 LACR_2276 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811845.1 2129019 D 272622 CDS YP_811846.1 116512939 4433273 complement(2129678..2130697) 1 NC_008527.1 ABC transporter permease 2130697 4433273 LACR_2277 Lactococcus lactis subsp. cremoris SK11 ABC transporter permease YP_811846.1 2129678 R 272622 CDS YP_811847.1 116512940 4433274 complement(2130690..2131460) 1 NC_008527.1 ABC-type multidrug transport system, ATPase component 2131460 4433274 LACR_2278 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase component YP_811847.1 2130690 R 272622 CDS YP_811848.1 116512941 4433275 complement(2131479..2133257) 1 NC_008527.1 glycerophosphoryl diester phosphodiesterase 2133257 4433275 LACR_2279 Lactococcus lactis subsp. cremoris SK11 glycerophosphoryl diester phosphodiesterase YP_811848.1 2131479 R 272622 CDS YP_811849.1 116512942 4433276 2133556..2133954 1 NC_008527.1 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 2133954 4433276 LACR_2280 Lactococcus lactis subsp. cremoris SK11 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases YP_811849.1 2133556 D 272622 CDS YP_811850.1 116512943 4433277 2133969..2134190 1 NC_008527.1 hypothetical protein 2134190 4433277 LACR_2281 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811850.1 2133969 D 272622 CDS YP_811851.1 116512944 4433278 complement(2134202..2134561) 1 NC_008527.1 hypothetical protein 2134561 4433278 LACR_2282 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811851.1 2134202 R 272622 CDS YP_811852.1 116512945 4433279 complement(2134624..2135313) 1 NC_008527.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 2135313 rplA 4433279 rplA Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L1 YP_811852.1 2134624 R 272622 CDS YP_811853.1 116512946 4433280 complement(2135700..2136125) 1 NC_008527.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 2136125 rplK 4433280 rplK Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L11 YP_811853.1 2135700 R 272622 CDS YP_811854.1 116512947 4433281 complement(2136261..2137025) 1 NC_008527.1 hypothetical protein 2137025 4433281 LACR_2285 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811854.1 2136261 R 272622 CDS YP_811855.1 116512948 4433282 complement(2137025..2137903) 1 NC_008527.1 ABC-type multidrug transport system, ATPase component 2137903 4433282 LACR_2286 Lactococcus lactis subsp. cremoris SK11 ABC-type multidrug transport system, ATPase component YP_811855.1 2137025 R 272622 CDS YP_811856.1 116512949 4433283 complement(2137970..2138179) 1 NC_008527.1 hypothetical protein 2138179 4433283 LACR_2287 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811856.1 2137970 R 272622 CDS YP_811857.1 116512950 4433284 complement(2138213..2138734) 1 NC_008527.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 2138734 4433284 LACR_2288 Lactococcus lactis subsp. cremoris SK11 methionine sulfoxide reductase A YP_811857.1 2138213 R 272622 CDS YP_811858.1 116512951 4433285 complement(2138909..2139766) 1 NC_008527.1 RNA-binding protein 2139766 4433285 LACR_2289 Lactococcus lactis subsp. cremoris SK11 RNA-binding protein YP_811858.1 2138909 R 272622 CDS YP_811859.1 116512952 4433286 complement(2139811..2140269) 1 NC_008527.1 acetyltransferase 2140269 4433286 LACR_2290 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_811859.1 2139811 R 272622 CDS YP_811860.1 116512953 4432328 complement(2140354..2140911) 1 NC_008527.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 2140911 frr 4432328 frr Lactococcus lactis subsp. cremoris SK11 ribosome recycling factor YP_811860.1 2140354 R 272622 CDS YP_811861.1 116512954 4432329 complement(2141067..2141783) 1 NC_008527.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 2141783 pyrH 4432329 pyrH Lactococcus lactis subsp. cremoris SK11 uridylate kinase YP_811861.1 2141067 R 272622 CDS YP_811862.1 116512955 4432330 complement(2141868..2142320) 1 NC_008527.1 hypothetical protein 2142320 4432330 LACR_2293 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811862.1 2141868 R 272622 CDS YP_811863.1 116512956 4432331 complement(2142450..2143637) 1 NC_008527.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2143637 4432331 LACR_2294 Lactococcus lactis subsp. cremoris SK11 acetate kinase YP_811863.1 2142450 R 272622 CDS YP_811864.1 116512957 4432332 complement(2143796..2144983) 1 NC_008527.1 acetate kinase 2144983 4432332 LACR_2295 Lactococcus lactis subsp. cremoris SK11 acetate kinase YP_811864.1 2143796 R 272622 CDS YP_811865.1 116512958 4432333 complement(2145175..2146113) 1 NC_008527.1 hypothetical protein 2146113 4432333 LACR_2296 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811865.1 2145175 R 272622 CDS YP_811866.1 116512959 4432334 complement(2146201..2146452) 1 NC_008527.1 hypothetical protein 2146452 4432334 LACR_2297 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811866.1 2146201 R 272622 CDS YP_811867.1 116512960 4432335 complement(2146553..2148394) 1 NC_008527.1 membrane GTPase for stress response 2148394 4432335 LACR_2298 Lactococcus lactis subsp. cremoris SK11 membrane GTPase for stress response YP_811867.1 2146553 R 272622 CDS YP_811868.1 116512961 4432336 complement(2148705..2149460) 1 NC_008527.1 transposase 2149460 4432336 LACR_2299 Lactococcus lactis subsp. cremoris SK11 transposase YP_811868.1 2148705 R 272622 CDS YP_811869.1 116512962 4432337 complement(2149457..2149717) 1 NC_008527.1 transposase 2149717 4432337 LACR_2300 Lactococcus lactis subsp. cremoris SK11 transposase YP_811869.1 2149457 R 272622 CDS YP_811870.1 116512963 4432338 complement(2149797..2150162) 1 NC_008527.1 hypothetical protein 2150162 4432338 LACR_2301 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811870.1 2149797 R 272622 CDS YP_811871.1 116512964 4432339 complement(2150191..2150496) 1 NC_008527.1 hypothetical protein 2150496 4432339 LACR_2302 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811871.1 2150191 R 272622 CDS YP_811872.1 116512965 4432340 2150663..2151553 1 NC_008527.1 transposase 2151553 4432340 LACR_2303 Lactococcus lactis subsp. cremoris SK11 transposase YP_811872.1 2150663 D 272622 CDS YP_811873.1 116512966 4432341 complement(2151614..2152072) 1 NC_008527.1 hypothetical protein 2152072 4432341 LACR_2304 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811873.1 2151614 R 272622 CDS YP_811874.1 116512967 4432342 complement(2152117..2152506) 1 NC_008527.1 hypothetical protein 2152506 4432342 LACR_2305 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811874.1 2152117 R 272622 CDS YP_811875.1 116512968 4432344 complement(2153042..2153770) 1 NC_008527.1 hypothetical protein 2153770 4432344 LACR_2307 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811875.1 2153042 R 272622 CDS YP_811876.1 116512969 4434442 2153963..2154184 1 NC_008527.1 hypothetical protein 2154184 4434442 LACR_2308 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811876.1 2153963 D 272622 CDS YP_811877.1 116512970 4434443 2154218..2155189 1 NC_008527.1 glucokinase 2155189 4434443 LACR_2309 Lactococcus lactis subsp. cremoris SK11 glucokinase YP_811877.1 2154218 D 272622 CDS YP_811878.1 116512971 4434444 2155192..2155578 1 NC_008527.1 hypothetical protein 2155578 4434444 LACR_2310 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811878.1 2155192 D 272622 CDS YP_811879.1 116512972 4434445 complement(2155694..2156140) 1 NC_008527.1 non-heme iron-binding ferritin 2156140 4434445 LACR_2311 Lactococcus lactis subsp. cremoris SK11 non-heme iron-binding ferritin YP_811879.1 2155694 R 272622 CDS YP_811880.1 116512973 4434446 2156277..2156864 1 NC_008527.1 type 4 prepilin-like protein specific leader peptidase 2156864 4434446 LACR_2312 Lactococcus lactis subsp. cremoris SK11 type 4 prepilin-like protein specific leader peptidase YP_811880.1 2156277 D 272622 CDS YP_811881.1 116512974 4434447 2156941..2157831 1 NC_008527.1 transposase 2157831 4434447 LACR_2313 Lactococcus lactis subsp. cremoris SK11 transposase YP_811881.1 2156941 D 272622 CDS YP_811882.1 116512975 4434448 complement(2157901..2158995) 1 NC_008527.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2158995 4434448 LACR_2314 Lactococcus lactis subsp. cremoris SK11 DNA polymerase IV YP_811882.1 2157901 R 272622 CDS YP_811883.1 116512976 4434449 complement(2159070..2159561) 1 NC_008527.1 hypothetical protein 2159561 4434449 LACR_2315 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811883.1 2159070 R 272622 CDS YP_811884.1 116512977 4434450 complement(2159636..2161129) 1 NC_008527.1 amino acid transporter 2161129 4434450 LACR_2316 Lactococcus lactis subsp. cremoris SK11 amino acid transporter YP_811884.1 2159636 R 272622 CDS YP_811885.1 116512978 4434451 complement(2161319..2162449) 1 NC_008527.1 associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 2162449 4434451 LACR_2317 Lactococcus lactis subsp. cremoris SK11 transaminase YP_811885.1 2161319 R 272622 CDS YP_811886.1 116512979 4434452 complement(2162713..2163657) 1 NC_008527.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2163657 4434452 LACR_2318 Lactococcus lactis subsp. cremoris SK11 carbamate kinase YP_811886.1 2162713 R 272622 CDS YP_811887.1 116512980 4434453 complement(2163690..2164634) 1 NC_008527.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2164634 4434453 LACR_2319 Lactococcus lactis subsp. cremoris SK11 carbamate kinase YP_811887.1 2163690 R 272622 CDS YP_811888.1 116512981 4434454 complement(2164652..2166232) 1 NC_008527.1 amino acid transporter 2166232 4434454 LACR_2320 Lactococcus lactis subsp. cremoris SK11 amino acid transporter YP_811888.1 2164652 R 272622 CDS YP_811889.1 116512982 4434455 complement(2166363..2167427) 1 NC_008527.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2167427 4434455 LACR_2321 Lactococcus lactis subsp. cremoris SK11 ornithine carbamoyltransferase YP_811889.1 2166363 R 272622 CDS YP_811890.1 116512983 4434457 complement(2169125..2170819) 1 NC_008527.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2170819 argS 4434457 argS Lactococcus lactis subsp. cremoris SK11 arginyl-tRNA synthetase YP_811890.1 2169125 R 272622 CDS YP_811891.1 116512984 4434458 2170887..2171345 1 NC_008527.1 ArgR family transcriptional regulator 2171345 4434458 LACR_2324 Lactococcus lactis subsp. cremoris SK11 ArgR family transcriptional regulator YP_811891.1 2170887 D 272622 CDS YP_811892.1 116512985 4434459 complement(2171462..2171557) 1 NC_008527.1 hypothetical protein 2171557 4434459 LACR_2325 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811892.1 2171462 R 272622 CDS YP_811893.1 116512986 4432781 complement(2171505..2172836) 1 NC_008527.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2172836 murC 4432781 murC Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylmuramate--L-alanine ligase YP_811893.1 2171505 R 272622 CDS YP_811894.1 116512987 4432782 complement(2173037..2173636) 1 NC_008527.1 hypothetical protein 2173636 4432782 LACR_2327 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811894.1 2173037 R 272622 CDS YP_811895.1 116512988 4432783 complement(2173800..2176904) 1 NC_008527.1 SNF2 family DNA/RNA helicase 2176904 4432783 LACR_2328 Lactococcus lactis subsp. cremoris SK11 SNF2 family DNA/RNA helicase YP_811895.1 2173800 R 272622 CDS YP_811896.1 116512989 4432784 2177242..2177502 1 NC_008527.1 transposase 2177502 4432784 LACR_2329 Lactococcus lactis subsp. cremoris SK11 transposase YP_811896.1 2177242 D 272622 CDS YP_811897.1 116512990 4432785 2177499..2178254 1 NC_008527.1 transposase 2178254 4432785 LACR_2330 Lactococcus lactis subsp. cremoris SK11 transposase YP_811897.1 2177499 D 272622 CDS YP_811898.1 116512991 4432787 complement(2178395..2178601) 1 NC_008527.1 hypothetical protein 2178601 4432787 LACR_2332 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811898.1 2178395 R 272622 CDS YP_811899.1 116512992 4432789 complement(2180724..2181680) 1 NC_008527.1 hypothetical protein 2181680 4432789 LACR_2334 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811899.1 2180724 R 272622 CDS YP_811900.1 116512993 4432790 complement(2181753..2182532) 1 NC_008527.1 hypothetical protein 2182532 4432790 LACR_2335 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811900.1 2181753 R 272622 CDS YP_811901.1 116512994 4432791 complement(2182761..2182922) 1 NC_008527.1 hypothetical protein 2182922 4432791 LACR_2336 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811901.1 2182761 R 272622 CDS YP_811902.1 116512995 4432792 complement(2182982..2184157) 1 NC_008527.1 transposase 2184157 4432792 LACR_2337 Lactococcus lactis subsp. cremoris SK11 transposase YP_811902.1 2182982 R 272622 CDS YP_811903.1 116512996 4432793 complement(2184315..2184644) 1 NC_008527.1 hypothetical protein 2184644 4432793 LACR_2338 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811903.1 2184315 R 272622 CDS YP_811904.1 116512997 4432794 complement(2184679..2185185) 1 NC_008527.1 hypothetical protein 2185185 4432794 LACR_2339 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811904.1 2184679 R 272622 CDS YP_811905.1 116512998 4432795 2185554..2186336 1 NC_008527.1 hypothetical protein 2186336 4432795 LACR_2340 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811905.1 2185554 D 272622 CDS YP_811906.1 116512999 4432796 complement(2186372..2187241) 1 NC_008527.1 glycerol uptake facilitator related permease (major Intrinsic protein family) 2187241 4432796 LACR_2341 Lactococcus lactis subsp. cremoris SK11 glycerol uptake facilitator related permease (major Intrinsic protein family) YP_811906.1 2186372 R 272622 CDS YP_811907.1 116513000 4432797 2187413..2189704 1 NC_008527.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 2189704 4432797 LACR_2342 Lactococcus lactis subsp. cremoris SK11 x-prolyl-dipeptidyl aminopeptidase YP_811907.1 2187413 D 272622 CDS YP_811908.1 116513001 4433963 2190567..2191409 1 NC_008527.1 amino acid ABC transporter periplasmic protein 2191409 4433963 LACR_2344 Lactococcus lactis subsp. cremoris SK11 amino acid ABC transporter periplasmic protein YP_811908.1 2190567 D 272622 CDS YP_811909.1 116513002 4433965 complement(2192930..2194381) 1 NC_008527.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2194381 gltX 4433965 gltX Lactococcus lactis subsp. cremoris SK11 glutamyl-tRNA synthetase YP_811909.1 2192930 R 272622 CDS YP_811910.1 116513003 4433966 complement(2194523..2195017) 1 NC_008527.1 amidase 2195017 4433966 LACR_2347 Lactococcus lactis subsp. cremoris SK11 amidase YP_811910.1 2194523 R 272622 CDS YP_811911.1 116513004 4433967 complement(2195021..2195563) 1 NC_008527.1 amidase 2195563 4433967 LACR_2348 Lactococcus lactis subsp. cremoris SK11 amidase YP_811911.1 2195021 R 272622 CDS YP_811912.1 116513005 4433968 2195672..2196127 1 NC_008527.1 fhu operon transcription regulator 2196127 4433968 LACR_2349 Lactococcus lactis subsp. cremoris SK11 fhu operon transcription regulator YP_811912.1 2195672 D 272622 CDS YP_811913.1 116513006 4433969 2196184..2197074 1 NC_008527.1 transposase 2197074 4433969 LACR_2350 Lactococcus lactis subsp. cremoris SK11 transposase YP_811913.1 2196184 D 272622 CDS YP_811914.1 116513007 4433970 2197144..2197563 1 NC_008527.1 hypothetical protein 2197563 4433970 LACR_2351 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811914.1 2197144 D 272622 CDS YP_811915.1 116513008 4433972 2198659..2199210 1 NC_008527.1 acetyltransferase 2199210 4433972 LACR_2353 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_811915.1 2198659 D 272622 CDS YP_811916.1 116513009 4433973 complement(2199301..2199624) 1 NC_008527.1 hypothetical protein 2199624 4433973 LACR_2354 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811916.1 2199301 R 272622 CDS YP_811917.1 116513010 4433974 complement(2199621..2199959) 1 NC_008527.1 hypothetical protein 2199959 4433974 LACR_2355 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811917.1 2199621 R 272622 CDS YP_811918.1 116513011 4433975 complement(2199952..2200308) 1 NC_008527.1 PadR family transcriptional regulator 2200308 4433975 LACR_2356 Lactococcus lactis subsp. cremoris SK11 PadR family transcriptional regulator YP_811918.1 2199952 R 272622 CDS YP_811919.1 116513012 4433976 complement(2200430..2201059) 1 NC_008527.1 hypothetical protein 2201059 4433976 LACR_2357 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811919.1 2200430 R 272622 CDS YP_811920.1 116513013 4433977 complement(2201117..2202202) 1 NC_008527.1 integral membrane protein 2202202 4433977 LACR_2358 Lactococcus lactis subsp. cremoris SK11 integral membrane protein YP_811920.1 2201117 R 272622 CDS YP_811921.1 116513014 4433978 2202469..2203152 1 NC_008527.1 hypothetical protein 2203152 4433978 LACR_2359 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811921.1 2202469 D 272622 CDS YP_811922.1 116513015 4433979 2203209..2204099 1 NC_008527.1 transposase 2204099 4433979 LACR_2360 Lactococcus lactis subsp. cremoris SK11 transposase YP_811922.1 2203209 D 272622 CDS YP_811923.1 116513016 4434217 complement(2204200..2205561) 1 NC_008527.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 2205561 4434217 LACR_2361 Lactococcus lactis subsp. cremoris SK11 DNA repair protein RadA YP_811923.1 2204200 R 272622 CDS YP_811924.1 116513017 4434218 2205792..2205878 1 NC_008527.1 hypothetical protein 2205878 4434218 LACR_2362 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811924.1 2205792 D 272622 CDS YP_811925.1 116513018 4434219 complement(2205837..2206742) 1 NC_008527.1 glycosyltransferase 2206742 4434219 LACR_2363 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_811925.1 2205837 R 272622 CDS YP_811926.1 116513019 4434220 complement(2206724..2207269) 1 NC_008527.1 D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase 2207269 4434220 LACR_2364 Lactococcus lactis subsp. cremoris SK11 D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase YP_811926.1 2206724 R 272622 CDS YP_811927.1 116513020 4434221 complement(2207266..2207841) 1 NC_008527.1 phosphoheptose isomerase 2207841 4434221 LACR_2365 Lactococcus lactis subsp. cremoris SK11 phosphoheptose isomerase YP_811927.1 2207266 R 272622 CDS YP_811928.1 116513021 4434223 complement(2208906..2210429) 1 NC_008527.1 membrane protein for polysaccharide transport 2210429 4434223 LACR_2367 Lactococcus lactis subsp. cremoris SK11 membrane protein for polysaccharide transport YP_811928.1 2208906 R 272622 CDS YP_811929.1 116513022 4434225 complement(2210689..2211414) 1 NC_008527.1 glycosyl transferase family protein 2211414 4434225 LACR_2369 Lactococcus lactis subsp. cremoris SK11 glycosyl transferase family protein YP_811929.1 2210689 R 272622 CDS YP_811930.1 116513023 4434226 complement(2211423..2212382) 1 NC_008527.1 glycosyltransferase 2212382 4434226 LACR_2370 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_811930.1 2211423 R 272622 CDS YP_811931.1 116513024 4434227 complement(2212401..2213381) 1 NC_008527.1 glycosyltransferase 2213381 4434227 LACR_2371 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_811931.1 2212401 R 272622 CDS YP_811932.1 116513025 4434228 complement(2213388..2214578) 1 NC_008527.1 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase 2214578 4434228 LACR_2372 Lactococcus lactis subsp. cremoris SK11 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase YP_811932.1 2213388 R 272622 CDS YP_811933.1 116513026 4434230 complement(2215290..2215670) 1 NC_008527.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2215670 rplQ 4434230 rplQ Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L17 YP_811933.1 2215290 R 272622 CDS YP_811934.1 116513027 4434231 complement(2215689..2216627) 1 NC_008527.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2216627 4434231 LACR_2375 Lactococcus lactis subsp. cremoris SK11 DNA-directed RNA polymerase subunit alpha YP_811934.1 2215689 R 272622 CDS YP_811935.1 116513028 4434232 complement(2216676..2217059) 1 NC_008527.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2217059 4434232 LACR_2376 Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S11 YP_811935.1 2216676 R 272622 CDS YP_811936.1 116513029 4433733 complement(2217080..2217445) 1 NC_008527.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2217445 rpsM 4433733 rpsM Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S13 YP_811936.1 2217080 R 272622 CDS YP_811937.1 116513030 4433734 complement(2217463..2217579) 1 NC_008527.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2217579 rpmJ 4433734 rpmJ Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L36 YP_811937.1 2217463 R 272622 CDS YP_811938.1 116513031 4433735 complement(2217633..2217851) 1 NC_008527.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2217851 infA 4433735 infA Lactococcus lactis subsp. cremoris SK11 translation initiation factor IF-1 YP_811938.1 2217633 R 272622 CDS YP_811939.1 116513032 4433736 complement(2218154..2218801) 1 NC_008527.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 2218801 adk 4433736 adk Lactococcus lactis subsp. cremoris SK11 adenylate kinase YP_811939.1 2218154 R 272622 CDS YP_811940.1 116513033 4433737 complement(2218941..2220260) 1 NC_008527.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2220260 secY 4433737 secY Lactococcus lactis subsp. cremoris SK11 preprotein translocase subunit SecY YP_811940.1 2218941 R 272622 CDS YP_811941.1 116513034 4433738 complement(2220338..2220781) 1 NC_008527.1 late assembly protein; 50S ribosomal protein L15 2220781 rplO 4433738 rplO Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L15 YP_811941.1 2220338 R 272622 CDS YP_811942.1 116513035 4433739 complement(2221074..2221253) 1 NC_008527.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2221253 rpmD 4433739 rpmD Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L30 YP_811942.1 2221074 R 272622 CDS YP_811943.1 116513036 4433740 complement(2221264..2221770) 1 NC_008527.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2221770 rpsE 4433740 rpsE Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S5 YP_811943.1 2221264 R 272622 CDS YP_811944.1 116513037 4433741 complement(2221789..2222136) 1 NC_008527.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2222136 rplR 4433741 rplR Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L18 YP_811944.1 2221789 R 272622 CDS YP_811945.1 116513038 4433742 complement(2222405..2222941) 1 NC_008527.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2222941 rplF 4433742 rplF Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L6 YP_811945.1 2222405 R 272622 CDS YP_811946.1 116513039 4433743 complement(2223158..2223556) 1 NC_008527.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2223556 rpsH 4433743 rpsH Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S8 YP_811946.1 2223158 R 272622 CDS YP_811947.1 116513040 4433744 complement(2223761..2224360) 1 NC_008527.1 hypothetical protein 2224360 4433744 LACR_2388 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811947.1 2223761 R 272622 CDS YP_811948.1 116513041 4433745 complement(2224511..2224696) 1 NC_008527.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 2224696 rpsN 4433745 rpsN Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S14 YP_811948.1 2224511 R 272622 CDS YP_811949.1 116513042 4433746 complement(2224715..2225257) 1 NC_008527.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2225257 rplE 4433746 rplE Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L5 YP_811949.1 2224715 R 272622 CDS YP_811950.1 116513043 4433747 complement(2225277..2225582) 1 NC_008527.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2225582 rplX 4433747 rplX Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L24 YP_811950.1 2225277 R 272622 CDS YP_811951.1 116513044 4433748 complement(2225716..2226084) 1 NC_008527.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2226084 rplN 4433748 rplN Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L14 YP_811951.1 2225716 R 272622 CDS YP_811952.1 116513045 4433749 complement(2226107..2226367) 1 NC_008527.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2226367 rpsQ 4433749 rpsQ Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S17 YP_811952.1 2226107 R 272622 CDS YP_811953.1 116513046 4433750 complement(2226388..2226597) 1 NC_008527.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 2226597 4433750 LACR_2394 Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L29 YP_811953.1 2226388 R 272622 CDS YP_811954.1 116513047 4433822 complement(2226597..2227010) 1 NC_008527.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2227010 rplP 4433822 rplP Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L16 YP_811954.1 2226597 R 272622 CDS YP_811955.1 116513048 4433823 complement(2227014..2227667) 1 NC_008527.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2227667 rpsC 4433823 rpsC Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S3 YP_811955.1 2227014 R 272622 CDS YP_811956.1 116513049 4433824 complement(2227680..2228027) 1 NC_008527.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2228027 rplV 4433824 rplV Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L22 YP_811956.1 2227680 R 272622 CDS YP_811957.1 116513050 4433825 complement(2228043..2228321) 1 NC_008527.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2228321 rpsS 4433825 rpsS Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S19 YP_811957.1 2228043 R 272622 CDS YP_811958.1 116513051 4433826 complement(2228481..2229311) 1 NC_008527.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2229311 rplB 4433826 rplB Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L2 YP_811958.1 2228481 R 272622 CDS YP_811959.1 116513052 4433827 complement(2229327..2229620) 1 NC_008527.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2229620 rplW 4433827 rplW Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L23 YP_811959.1 2229327 R 272622 CDS YP_811960.1 116513053 4433828 complement(2229620..2230246) 1 NC_008527.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2230246 rplD 4433828 rplD Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L4 YP_811960.1 2229620 R 272622 CDS YP_811961.1 116513054 4433829 complement(2230915..2231223) 1 NC_008527.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2231223 rpsJ 4433829 rpsJ Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S10 YP_811961.1 2230915 R 272622 CDS YP_811962.1 116513055 4433830 2231557..2231922 1 NC_008527.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 2231922 mscL 4433830 mscL Lactococcus lactis subsp. cremoris SK11 large-conductance mechanosensitive channel YP_811962.1 2231557 D 272622 CDS YP_811963.1 116513056 4433831 complement(2231961..2233250) 1 NC_008527.1 hypothetical protein 2233250 4433831 LACR_2404 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811963.1 2231961 R 272622 CDS YP_811964.1 116513057 4433832 complement(2233247..2234737) 1 NC_008527.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 2234737 4433832 LACR_2405 Lactococcus lactis subsp. cremoris SK11 threonine synthase YP_811964.1 2233247 R 272622 CDS YP_811965.1 116513058 4433833 complement(2234836..2235393) 1 NC_008527.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 2235393 nusG 4433833 nusG Lactococcus lactis subsp. cremoris SK11 transcription antitermination protein NusG YP_811965.1 2234836 R 272622 CDS YP_811966.1 116513059 4433834 complement(2235600..2235794) 1 NC_008527.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 2235794 secE 4433834 secE Lactococcus lactis subsp. cremoris SK11 preprotein translocase subunit SecE YP_811966.1 2235600 R 272622 CDS YP_811967.1 116513060 4433835 complement(2235906..2236055) 1 NC_008527.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 2236055 rpmG 4433835 rpmG Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L33 YP_811967.1 2235906 R 272622 CDS YP_811968.1 116513061 4433836 complement(2236096..2237913) 1 NC_008527.1 hypothetical protein 2237913 4433836 LACR_2409 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811968.1 2236096 R 272622 CDS YP_811969.1 116513062 4433837 complement(2238015..2240246) 1 NC_008527.1 membrane carboxypeptidase (penicillin-binding protein) 2240246 4433837 LACR_2410 Lactococcus lactis subsp. cremoris SK11 membrane carboxypeptidase (penicillin-binding protein) YP_811969.1 2238015 R 272622 CDS YP_811970.1 116513063 4433838 complement(2240632..2241267) 1 NC_008527.1 hypothetical protein 2241267 4433838 LACR_2411 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811970.1 2240632 R 272622 CDS YP_811971.1 116513064 4433018 complement(2241285..2241716) 1 NC_008527.1 hypothetical protein 2241716 4433018 LACR_2412 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811971.1 2241285 R 272622 CDS YP_811972.1 116513065 4433019 complement(2241831..2242073) 1 NC_008527.1 FMN-binding protein 2242073 4433019 LACR_2413 Lactococcus lactis subsp. cremoris SK11 FMN-binding protein YP_811972.1 2241831 R 272622 CDS YP_811973.1 116513066 4433020 2242402..2243274 1 NC_008527.1 pseudouridylate synthase, 23S RNA-specific 2243274 4433020 LACR_2414 Lactococcus lactis subsp. cremoris SK11 pseudouridylate synthase, 23S RNA-specific YP_811973.1 2242402 D 272622 CDS YP_811974.1 116513067 4433021 complement(2243338..2244201) 1 NC_008527.1 transposase 2244201 4433021 LACR_2415 Lactococcus lactis subsp. cremoris SK11 transposase YP_811974.1 2243338 R 272622 CDS YP_811975.1 116513068 4433022 complement(2244150..2244731) 1 NC_008527.1 transposase 2244731 4433022 LACR_2416 Lactococcus lactis subsp. cremoris SK11 transposase YP_811975.1 2244150 R 272622 CDS YP_811976.1 116513069 4433023 complement(2244804..2245613) 1 NC_008527.1 zinc ABC transporter permease 2245613 4433023 LACR_2417 Lactococcus lactis subsp. cremoris SK11 zinc ABC transporter permease YP_811976.1 2244804 R 272622 CDS YP_811977.1 116513070 4433024 complement(2245606..2246343) 1 NC_008527.1 zinc ABC transporter ATP-binding protein 2246343 4433024 LACR_2418 Lactococcus lactis subsp. cremoris SK11 zinc ABC transporter ATP-binding protein YP_811977.1 2245606 R 272622 CDS YP_811978.1 116513071 4433025 complement(2246522..2247364) 1 NC_008527.1 zinc ABC transporter substrate-binding protein 2247364 4433025 LACR_2419 Lactococcus lactis subsp. cremoris SK11 zinc ABC transporter substrate-binding protein YP_811978.1 2246522 R 272622 CDS YP_811979.1 116513072 4433026 complement(2247361..2247798) 1 NC_008527.1 transcriptional regulator 2247798 4433026 LACR_2420 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_811979.1 2247361 R 272622 CDS YP_811980.1 116513073 4433027 complement(2247878..2248177) 1 NC_008527.1 hypothetical protein 2248177 4433027 LACR_2421 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811980.1 2247878 R 272622 CDS YP_811981.1 116513074 4433028 complement(2248201..2248626) 1 NC_008527.1 hypothetical protein 2248626 4433028 LACR_2422 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811981.1 2248201 R 272622 CDS YP_811982.1 116513075 4433029 complement(2248610..2248906) 1 NC_008527.1 hypothetical protein 2248906 4433029 LACR_2423 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811982.1 2248610 R 272622 CDS YP_811983.1 116513076 4433031 complement(2249268..2249645) 1 NC_008527.1 competence protein ComGC 2249645 4433031 LACR_2425 Lactococcus lactis subsp. cremoris SK11 competence protein ComGC YP_811983.1 2249268 R 272622 CDS YP_811984.1 116513077 4433034 2251513..2252403 1 NC_008527.1 transposase 2252403 4433034 LACR_2428 Lactococcus lactis subsp. cremoris SK11 transposase YP_811984.1 2251513 D 272622 CDS YP_811985.1 116513078 4433035 complement(2252691..2257598) 1 NC_008527.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 2257598 polC 4433035 polC Lactococcus lactis subsp. cremoris SK11 DNA polymerase III PolC YP_811985.1 2252691 R 272622 CDS YP_811986.1 116513079 4432294 complement(2257772..2258074) 1 NC_008527.1 hypothetical protein 2258074 4432294 LACR_2430 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811986.1 2257772 R 272622 CDS YP_811987.1 116513080 4432295 complement(2258233..2259564) 1 NC_008527.1 NAD(FAD)-dependent dehydrogenase 2259564 4432295 LACR_2431 Lactococcus lactis subsp. cremoris SK11 NAD(FAD)-dependent dehydrogenase YP_811987.1 2258233 R 272622 CDS YP_811988.1 116513081 4432296 complement(2259580..2261430) 1 NC_008527.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 2261430 4432296 LACR_2432 Lactococcus lactis subsp. cremoris SK11 prolyl-tRNA synthetase YP_811988.1 2259580 R 272622 CDS YP_811989.1 116513082 4432297 complement(2261500..2262786) 1 NC_008527.1 membrane-associated Zn-dependent protease 1 2262786 4432297 LACR_2433 Lactococcus lactis subsp. cremoris SK11 membrane-associated Zn-dependent protease 1 YP_811989.1 2261500 R 272622 CDS YP_811990.1 116513083 4432298 complement(2262805..2263608) 1 NC_008527.1 phosphatidate cytidylyltransferase 2263608 4432298 LACR_2434 Lactococcus lactis subsp. cremoris SK11 phosphatidate cytidylyltransferase YP_811990.1 2262805 R 272622 CDS YP_811991.1 116513084 4432299 complement(2263608..2264342) 1 NC_008527.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 2264342 4432299 LACR_2435 Lactococcus lactis subsp. cremoris SK11 undecaprenyl pyrophosphate synthase YP_811991.1 2263608 R 272622 CDS YP_811992.1 116513085 4432300 complement(2264692..2265024) 1 NC_008527.1 hypothetical protein 2265024 4432300 LACR_2436 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811992.1 2264692 R 272622 CDS YP_811993.1 116513086 4432301 complement(2265185..2265817) 1 NC_008527.1 DNA-7-methylguanine glycosylase 2265817 4432301 LACR_2437 Lactococcus lactis subsp. cremoris SK11 DNA-7-methylguanine glycosylase YP_811993.1 2265185 R 272622 CDS YP_811994.1 116513087 4432302 complement(2265835..2266314) 1 NC_008527.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2266314 4432302 LACR_2438 Lactococcus lactis subsp. cremoris SK11 rRNA large subunit methyltransferase YP_811994.1 2265835 R 272622 CDS YP_811995.1 116513088 4432303 2266690..2267913 1 NC_008527.1 trypsin-like serine protease 2267913 4432303 LACR_2439 Lactococcus lactis subsp. cremoris SK11 trypsin-like serine protease YP_811995.1 2266690 D 272622 CDS YP_811996.1 116513089 4432304 2268035..2269033 1 NC_008527.1 glycosyltransferase 2269033 4432304 LACR_2440 Lactococcus lactis subsp. cremoris SK11 glycosyltransferase YP_811996.1 2268035 D 272622 CDS YP_811997.1 116513090 4432305 2269171..2270511 1 NC_008527.1 1,2-diacylglycerol 3-glucosyltransferase 2270511 4432305 LACR_2441 Lactococcus lactis subsp. cremoris SK11 1,2-diacylglycerol 3-glucosyltransferase YP_811997.1 2269171 D 272622 CDS YP_811998.1 116513091 4432306 2270619..2270843 1 NC_008527.1 hypothetical protein 2270843 4432306 LACR_2442 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811998.1 2270619 D 272622 CDS YP_811999.1 116513092 4432307 2270982..2271986 1 NC_008527.1 hypothetical protein 2271986 4432307 LACR_2443 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_811999.1 2270982 D 272622 CDS YP_812000.1 116513093 4432308 complement(2272043..2272774) 1 NC_008527.1 hypothetical protein 2272774 4432308 LACR_2444 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812000.1 2272043 R 272622 CDS YP_812001.1 116513094 4432309 complement(2273003..2275636) 1 NC_008527.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 2275636 4432309 LACR_2445 Lactococcus lactis subsp. cremoris SK11 DNA polymerase I YP_812001.1 2273003 R 272622 CDS YP_812002.1 116513095 4432310 2275898..2276707 1 NC_008527.1 HAD superfamily hydrolase 2276707 4432310 LACR_2446 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_812002.1 2275898 D 272622 CDS YP_812003.1 116513096 4432579 2276707..2277312 1 NC_008527.1 LacI family transcription regulator 2277312 4432579 LACR_2447 Lactococcus lactis subsp. cremoris SK11 LacI family transcription regulator YP_812003.1 2276707 D 272622 CDS YP_812004.1 116513097 4432584 complement(2283148..2283498) 1 NC_008527.1 ComX 2283498 4432584 LACR_2452 Lactococcus lactis subsp. cremoris SK11 ComX YP_812004.1 2283148 R 272622 CDS YP_812005.1 116513098 4432585 complement(2283762..2285492) 1 NC_008527.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 2285492 4432585 LACR_2453 Lactococcus lactis subsp. cremoris SK11 septation ring formation regulator EzrA YP_812005.1 2283762 R 272622 CDS YP_812006.1 116513099 4432586 complement(2285697..2286725) 1 NC_008527.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2286725 tsf 4432586 tsf Lactococcus lactis subsp. cremoris SK11 elongation factor Ts YP_812006.1 2285697 R 272622 CDS YP_812007.1 116513100 4432587 complement(2286847..2287614) 1 NC_008527.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2287614 rpsB 4432587 rpsB Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S2 YP_812007.1 2286847 R 272622 CDS YP_812008.1 116513101 4432588 2288009..2289034 1 NC_008527.1 hypothetical protein 2289034 4432588 LACR_2456 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812008.1 2288009 D 272622 CDS YP_812009.1 116513102 4432589 2289290..2292001 1 NC_008527.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2292001 4432589 LACR_2457 Lactococcus lactis subsp. cremoris SK11 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_812009.1 2289290 D 272622 CDS YP_812010.1 116513103 4432590 complement(2292276..2292383) 1 NC_008527.1 hypothetical protein 2292383 4432590 LACR_2458 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812010.1 2292276 R 272622 CDS YP_812011.1 116513104 4432591 complement(2292465..2292962) 1 NC_008527.1 hypothetical protein 2292962 4432591 LACR_2459 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812011.1 2292465 R 272622 CDS YP_812012.1 116513105 4432592 complement(2292949..2293158) 1 NC_008527.1 hypothetical protein 2293158 4432592 LACR_2460 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812012.1 2292949 R 272622 CDS YP_812013.1 116513106 4432897 2293446..2294336 1 NC_008527.1 transposase 2294336 4432897 LACR_2462 Lactococcus lactis subsp. cremoris SK11 transposase YP_812013.1 2293446 D 272622 CDS YP_812014.1 116513107 4432898 complement(2296262..2297293) 1 NC_008527.1 protease 2297293 4432898 LACR_2463 Lactococcus lactis subsp. cremoris SK11 protease YP_812014.1 2296262 R 272622 CDS YP_812015.1 116513108 4432899 complement(2297277..2297777) 1 NC_008527.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 2297777 coaD 4432899 coaD Lactococcus lactis subsp. cremoris SK11 phosphopantetheine adenylyltransferase YP_812015.1 2297277 R 272622 CDS YP_812016.1 116513109 4432900 complement(2297825..2298391) 1 NC_008527.1 hypothetical protein 2298391 4432900 LACR_2465 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812016.1 2297825 R 272622 CDS YP_812017.1 116513110 4432901 complement(2298535..2299755) 1 NC_008527.1 major facilitator superfamily permease 2299755 4432901 LACR_2466 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_812017.1 2298535 R 272622 CDS YP_812018.1 116513111 4432903 2301256..2301747 1 NC_008527.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24-like protein 2301747 4432903 LACR_2468 Lactococcus lactis subsp. cremoris SK11 DNA-directed RNA polymerase specialized sigma subunit, sigma24-like protein YP_812018.1 2301256 D 272622 CDS YP_812019.1 116513112 4432904 2301771..2302877 1 NC_008527.1 hypothetical protein 2302877 4432904 LACR_2469 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812019.1 2301771 D 272622 CDS YP_812020.1 116513113 4432905 complement(2302972..2304318) 1 NC_008527.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 2304318 pgi 4432905 pgi Lactococcus lactis subsp. cremoris SK11 glucose-6-phosphate isomerase YP_812020.1 2302972 R 272622 CDS YP_812021.1 116513114 4432906 complement(2304417..2304548) 1 NC_008527.1 hypothetical protein 2304548 4432906 LACR_2471 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812021.1 2304417 R 272622 CDS YP_812022.1 116513115 4432907 2304665..2305168 1 NC_008527.1 hypothetical protein 2305168 4432907 LACR_2472 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812022.1 2304665 D 272622 CDS YP_812023.1 116513116 4432908 complement(2305202..2305942) 1 NC_008527.1 Short-chain alcohol dehydrogenase 2305942 4432908 LACR_2473 Lactococcus lactis subsp. cremoris SK11 Short-chain alcohol dehydrogenase YP_812023.1 2305202 R 272622 CDS YP_812024.1 116513117 4432909 complement(2305988..2306791) 1 NC_008527.1 XRE family transcriptional regulator 2306791 4432909 LACR_2474 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_812024.1 2305988 R 272622 CDS YP_812025.1 116513118 4432910 complement(2306861..2307706) 1 NC_008527.1 hypothetical protein 2307706 4432910 LACR_2475 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812025.1 2306861 R 272622 CDS YP_812026.1 116513119 4432911 2307954..2308217 1 NC_008527.1 transcriptional regulator 2308217 4432911 LACR_2476 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_812026.1 2307954 D 272622 CDS YP_812027.1 116513120 4432912 2308423..2309598 1 NC_008527.1 transposase 2309598 4432912 LACR_2477 Lactococcus lactis subsp. cremoris SK11 transposase YP_812027.1 2308423 D 272622 CDS YP_812028.1 116513121 4432913 2309652..2309984 1 NC_008527.1 hypothetical protein 2309984 4432913 LACR_2478 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812028.1 2309652 D 272622 CDS YP_812029.1 116513122 4432697 complement(2310028..2312670) 1 NC_008527.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 2312670 valS 4432697 valS Lactococcus lactis subsp. cremoris SK11 valyl-tRNA synthetase YP_812029.1 2310028 R 272622 CDS YP_812030.1 116513123 4432698 complement(2312706..2313200) 1 NC_008527.1 hypothetical protein 2313200 4432698 LACR_2480 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812030.1 2312706 R 272622 CDS YP_812032.1 116513125 4432701 complement(2314648..2314896) 1 NC_008527.1 hypothetical protein 2314896 4432701 LACR_2483 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812032.1 2314648 R 272622 CDS YP_812033.1 116513126 4432702 complement(2314969..2315313) 1 NC_008527.1 hypothetical protein 2315313 4432702 LACR_2484 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812033.1 2314969 R 272622 CDS YP_812034.1 116513127 4432703 complement(2315306..2315818) 1 NC_008527.1 acetyltransferase 2315818 4432703 LACR_2485 Lactococcus lactis subsp. cremoris SK11 acetyltransferase YP_812034.1 2315306 R 272622 CDS YP_812035.1 116513128 4432704 complement(2316028..2316747) 1 NC_008527.1 Solo B3/4 domain-containing protein 2316747 4432704 LACR_2486 Lactococcus lactis subsp. cremoris SK11 Solo B3/4 domain-containing protein YP_812035.1 2316028 R 272622 CDS YP_812036.1 116513129 4432705 complement(2316828..2318369) 1 NC_008527.1 tRNA (uracil-5-)-methyltransferase related enzyme 2318369 4432705 LACR_2487 Lactococcus lactis subsp. cremoris SK11 tRNA (uracil-5-)-methyltransferase related enzyme YP_812036.1 2316828 R 272622 CDS YP_812037.1 116513130 4432707 complement(2320855..2321373) 1 NC_008527.1 hypothetical protein 2321373 4432707 LACR_2489 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812037.1 2320855 R 272622 CDS YP_812038.1 116513131 4432708 2321730..2322539 1 NC_008527.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2322539 recX 4432708 recX Lactococcus lactis subsp. cremoris SK11 recombination regulator RecX YP_812038.1 2321730 D 272622 CDS YP_812039.1 116513132 4434138 complement(2329434..2330933) 1 NC_008527.1 gluconate kinase 2330933 4434138 LACR_2496 Lactococcus lactis subsp. cremoris SK11 gluconate kinase YP_812039.1 2329434 R 272622 CDS YP_812040.1 116513133 4434139 complement(2331200..2332105) 1 NC_008527.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase-like protein 2332105 4434139 LACR_2497 Lactococcus lactis subsp. cremoris SK11 6-phosphogluconate dehydrogenase-like protein YP_812040.1 2331200 R 272622 CDS YP_812041.1 116513134 4434140 2332474..2333322 1 NC_008527.1 transcriptional regulator 2333322 4434140 LACR_2498 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_812041.1 2332474 D 272622 CDS YP_812042.1 116513135 4434141 2333361..2333669 1 NC_008527.1 hypothetical protein 2333669 4434141 LACR_2499 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812042.1 2333361 D 272622 CDS YP_812043.1 116513136 4434142 complement(2333742..2334497) 1 NC_008527.1 hypothetical protein 2334497 4434142 LACR_2500 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812043.1 2333742 R 272622 CDS YP_812044.1 116513137 4434143 complement(2334658..2334903) 1 NC_008527.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 2334903 rpsR 4434143 rpsR Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S18 YP_812044.1 2334658 R 272622 CDS YP_812045.1 116513138 4434144 complement(2335075..2335575) 1 NC_008527.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 2335575 4434144 LACR_2502 Lactococcus lactis subsp. cremoris SK11 single-stranded DNA-binding protein YP_812045.1 2335075 R 272622 CDS YP_812046.1 116513139 4434145 complement(2335605..2335898) 1 NC_008527.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 2335898 rpsF 4434145 rpsF Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S6 YP_812046.1 2335605 R 272622 CDS YP_812047.1 116513140 4434146 complement(2336092..2336946) 1 NC_008527.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 2336946 4434146 LACR_2504 Lactococcus lactis subsp. cremoris SK11 undecaprenyl pyrophosphate phosphatase YP_812047.1 2336092 R 272622 CDS YP_812048.1 116513141 4434147 2337468..2338934 1 NC_008527.1 amino acid transporter 2338934 4434147 LACR_2505 Lactococcus lactis subsp. cremoris SK11 amino acid transporter YP_812048.1 2337468 D 272622 CDS YP_812049.1 116513142 4434148 complement(2338968..2340629) 1 NC_008527.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 2340629 4434148 LACR_2506 Lactococcus lactis subsp. cremoris SK11 DNA polymerase III subunits gamma and tau YP_812049.1 2338968 R 272622 CDS YP_812050.1 116513143 4434149 complement(2340675..2341316) 1 NC_008527.1 hypothetical protein 2341316 4434149 LACR_2507 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812050.1 2340675 R 272622 CDS YP_812051.1 116513144 4434150 complement(2341348..2341836) 1 NC_008527.1 GAF domain-containing protein 2341836 4434150 LACR_2508 Lactococcus lactis subsp. cremoris SK11 GAF domain-containing protein YP_812051.1 2341348 R 272622 CDS YP_812052.1 116513145 4434151 2341920..2342192 1 NC_008527.1 hypothetical protein 2342192 4434151 LACR_2509 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812052.1 2341920 D 272622 CDS YP_812053.1 116513146 4433377 complement(2342226..2342675) 1 NC_008527.1 hypothetical protein 2342675 4433377 LACR_2510 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812053.1 2342226 R 272622 CDS YP_812054.1 116513147 4433378 2342893..2343093 1 NC_008527.1 hypothetical protein 2343093 4433378 LACR_2511 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812054.1 2342893 D 272622 CDS YP_812055.1 116513148 4433379 complement(2343154..2344494) 1 NC_008527.1 L-glutamine synthetase 2344494 4433379 LACR_2512 Lactococcus lactis subsp. cremoris SK11 L-glutamine synthetase YP_812055.1 2343154 R 272622 CDS YP_812056.1 116513149 4433380 complement(2344556..2344924) 1 NC_008527.1 glutamine synthetase 2344924 4433380 LACR_2513 Lactococcus lactis subsp. cremoris SK11 glutamine synthetase YP_812056.1 2344556 R 272622 CDS YP_812057.1 116513150 4433381 complement(2345022..2345459) 1 NC_008527.1 protein tyrosine phosphatase 2345459 4433381 LACR_2514 Lactococcus lactis subsp. cremoris SK11 protein tyrosine phosphatase YP_812057.1 2345022 R 272622 CDS YP_812058.1 116513151 4433382 complement(2345604..2346605) 1 NC_008527.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2346605 ruvB 4433382 ruvB Lactococcus lactis subsp. cremoris SK11 Holliday junction DNA helicase RuvB YP_812058.1 2345604 R 272622 CDS YP_812059.1 116513152 4433383 complement(2346753..2347346) 1 NC_008527.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2347346 ruvA 4433383 ruvA Lactococcus lactis subsp. cremoris SK11 Holliday junction DNA helicase RuvA YP_812059.1 2346753 R 272622 CDS YP_812060.1 116513153 4433384 complement(2347398..2349368) 1 NC_008527.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 2349368 mutL 4433384 mutL Lactococcus lactis subsp. cremoris SK11 DNA mismatch repair protein YP_812060.1 2347398 R 272622 CDS YP_812061.1 116513154 4433385 complement(2349498..2350193) 1 NC_008527.1 hypothetical protein 2350193 4433385 LACR_2518 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812061.1 2349498 R 272622 CDS YP_812062.1 116513155 4433386 complement(2350303..2352825) 1 NC_008527.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2352825 4433386 LACR_2519 Lactococcus lactis subsp. cremoris SK11 DNA mismatch repair protein MutS YP_812062.1 2350303 R 272622 CDS YP_812063.1 116513156 4433387 complement(2352940..2353287) 1 NC_008527.1 hypothetical protein 2353287 4433387 LACR_2520 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812063.1 2352940 R 272622 CDS YP_812064.1 116513157 4433389 complement(2354375..2354581) 1 NC_008527.1 hypothetical protein 2354581 4433389 LACR_2522 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812064.1 2354375 R 272622 CDS YP_812065.1 116513158 4433391 complement(2354926..2355303) 1 NC_008527.1 hypothetical protein 2355303 4433391 LACR_2524 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812065.1 2354926 R 272622 CDS YP_812066.1 116513159 4433392 complement(2355303..2356154) 1 NC_008527.1 permease 2356154 4433392 LACR_2525 Lactococcus lactis subsp. cremoris SK11 permease YP_812066.1 2355303 R 272622 CDS YP_812067.1 116513160 4432158 2356338..2356517 1 NC_008527.1 hypothetical protein 2356517 4432158 LACR_2526 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812067.1 2356338 D 272622 CDS YP_812068.1 116513161 4432159 2356637..2358148 1 NC_008527.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2358148 4432159 LACR_2527 Lactococcus lactis subsp. cremoris SK11 glucose-6-phosphate 1-dehydrogenase YP_812068.1 2356637 D 272622 CDS YP_812069.1 116513162 4432160 complement(2358344..2358871) 1 NC_008527.1 HAD superfamily hydrolase 2358871 4432160 LACR_2528 Lactococcus lactis subsp. cremoris SK11 HAD superfamily hydrolase YP_812069.1 2358344 R 272622 CDS YP_812070.1 116513163 4432161 complement(2359001..2360140) 1 NC_008527.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 2360140 4432161 LACR_2529 Lactococcus lactis subsp. cremoris SK11 chaperone protein DnaJ YP_812070.1 2359001 R 272622 CDS YP_812071.1 116513164 4432162 complement(2360251..2360997) 1 NC_008527.1 hypothetical protein 2360997 4432162 LACR_2530 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812071.1 2360251 R 272622 CDS YP_812072.1 116513165 4432163 complement(2360987..2361709) 1 NC_008527.1 aspartate racemase 2361709 4432163 LACR_2531 Lactococcus lactis subsp. cremoris SK11 aspartate racemase YP_812072.1 2360987 R 272622 CDS YP_812073.1 116513166 4432164 complement(2361741..2362967) 1 NC_008527.1 hypothetical protein 2362967 4432164 LACR_2532 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812073.1 2361741 R 272622 CDS YP_812074.1 116513167 4432165 complement(2362979..2364856) 1 NC_008527.1 asparagine synthase (glutamine-hydrolyzing) 2364856 4432165 LACR_2533 Lactococcus lactis subsp. cremoris SK11 asparagine synthase (glutamine-hydrolyzing) YP_812074.1 2362979 R 272622 CDS YP_812075.1 116513168 4432166 complement(2364978..2366318) 1 NC_008527.1 surface antigen 2366318 4432166 LACR_2534 Lactococcus lactis subsp. cremoris SK11 surface antigen YP_812075.1 2364978 R 272622 CDS YP_812076.1 116513169 4432167 complement(2366422..2366949) 1 NC_008527.1 rod shape-determining protein MreD 2366949 4432167 LACR_2535 Lactococcus lactis subsp. cremoris SK11 rod shape-determining protein MreD YP_812076.1 2366422 R 272622 CDS YP_812077.1 116513170 4432168 complement(2367028..2367903) 1 NC_008527.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2367903 4432168 LACR_2536 Lactococcus lactis subsp. cremoris SK11 rod shape-determining protein MreC YP_812077.1 2367028 R 272622 CDS YP_812078.1 116513171 4432169 2368195..2368635 1 NC_008527.1 NUDIX family hydrolase 2368635 4432169 LACR_2537 Lactococcus lactis subsp. cremoris SK11 NUDIX family hydrolase YP_812078.1 2368195 D 272622 CDS YP_812079.1 116513172 4432170 complement(2368660..2369334) 1 NC_008527.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2369334 4432170 LACR_2538 Lactococcus lactis subsp. cremoris SK11 ribose-5-phosphate isomerase A YP_812079.1 2368660 R 272622 CDS YP_812080.1 116513173 4432171 complement(2369418..2370089) 1 NC_008527.1 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase 2370089 4432171 LACR_2539 Lactococcus lactis subsp. cremoris SK11 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase YP_812080.1 2369418 R 272622 CDS YP_812081.1 116513174 4432172 complement(2370203..2371420) 1 NC_008527.1 major facilitator superfamily permease 2371420 4432172 LACR_2540 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_812081.1 2370203 R 272622 CDS YP_812082.1 116513175 4432173 complement(2371471..2371908) 1 NC_008527.1 universal stress protein UspA-like nucleotide-binding protein 2371908 4432173 LACR_2541 Lactococcus lactis subsp. cremoris SK11 universal stress protein UspA-like nucleotide-binding protein YP_812082.1 2371471 R 272622 CDS YP_812083.1 116513176 4432174 complement(2371928..2372131) 1 NC_008527.1 hypothetical protein 2372131 4432174 LACR_2542 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812083.1 2371928 R 272622 CDS YP_812084.1 116513177 4432175 complement(2372357..2376667) 1 NC_008527.1 2-hydroxyglutaryl-CoA dehydratase activator 2376667 4432175 LACR_2543 Lactococcus lactis subsp. cremoris SK11 2-hydroxyglutaryl-CoA dehydratase activator YP_812084.1 2372357 R 272622 CDS YP_812085.1 116513178 4432124 2377069..2377692 1 NC_008527.1 TetR family transcriptional regulator 2377692 4432124 LACR_2544 Lactococcus lactis subsp. cremoris SK11 TetR family transcriptional regulator YP_812085.1 2377069 D 272622 CDS YP_812086.1 116513179 4432125 complement(2377776..2378504) 1 NC_008527.1 ribosomal small subunit pseudouridine synthase A 2378504 4432125 LACR_2545 Lactococcus lactis subsp. cremoris SK11 ribosomal small subunit pseudouridine synthase A YP_812086.1 2377776 R 272622 CDS YP_812087.1 116513180 4432126 complement(2378735..2379370) 1 NC_008527.1 hypothetical protein 2379370 4432126 LACR_2546 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812087.1 2378735 R 272622 CDS YP_812088.1 116513181 4432127 2379669..2381036 1 NC_008527.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2381036 trmE 4432127 trmE Lactococcus lactis subsp. cremoris SK11 tRNA modification GTPase TrmE YP_812088.1 2379669 D 272622 CDS YP_812089.1 116513182 4432128 complement(2381061..2382281) 1 NC_008527.1 major facilitator superfamily permease 2382281 4432128 LACR_2548 Lactococcus lactis subsp. cremoris SK11 major facilitator superfamily permease YP_812089.1 2381061 R 272622 CDS YP_812090.1 116513183 4432129 complement(2382278..2384122) 1 NC_008527.1 Serine/threonine protein kinase 2384122 4432129 LACR_2549 Lactococcus lactis subsp. cremoris SK11 Serine/threonine protein kinase YP_812090.1 2382278 R 272622 CDS YP_812091.1 116513184 4432130 complement(2384174..2384272) 1 NC_008527.1 hypothetical protein 2384272 4432130 LACR_2550 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812091.1 2384174 R 272622 CDS YP_812092.1 116513185 4432131 complement(2384356..2385195) 1 NC_008527.1 XRE family transcriptional regulator 2385195 4432131 LACR_2551 Lactococcus lactis subsp. cremoris SK11 XRE family transcriptional regulator YP_812092.1 2384356 R 272622 CDS YP_812093.1 116513186 4432132 complement(2385274..2386011) 1 NC_008527.1 hypothetical protein 2386011 4432132 LACR_2552 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812093.1 2385274 R 272622 CDS YP_812094.1 116513187 4432133 complement(2386011..2388056) 1 NC_008527.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 2388056 4432133 LACR_2553 Lactococcus lactis subsp. cremoris SK11 ATP-dependent DNA helicase RecG YP_812094.1 2386011 R 272622 CDS YP_812095.1 116513188 4432134 complement(2388150..2388494) 1 NC_008527.1 hypothetical protein 2388494 4432134 LACR_2554 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812095.1 2388150 R 272622 CDS YP_812096.1 116513189 4432135 complement(2388562..2389572) 1 NC_008527.1 glyceraldehyde 3-phosphate dehydrogenase 2389572 4432135 LACR_2555 Lactococcus lactis subsp. cremoris SK11 glyceraldehyde 3-phosphate dehydrogenase YP_812096.1 2388562 R 272622 CDS YP_812097.1 116513190 4432136 complement(2389849..2390361) 1 NC_008527.1 hypothetical protein 2390361 4432136 LACR_2556 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812097.1 2389849 R 272622 CDS YP_812098.1 116513191 4432137 2390499..2393192 1 NC_008527.1 cation transport ATPase 2393192 4432137 LACR_2557 Lactococcus lactis subsp. cremoris SK11 cation transport ATPase YP_812098.1 2390499 D 272622 CDS YP_812099.1 116513192 4432138 complement(2393234..2393761) 1 NC_008527.1 transcriptional regulator 2393761 4432138 LACR_2558 Lactococcus lactis subsp. cremoris SK11 transcriptional regulator YP_812099.1 2393234 R 272622 CDS YP_812100.1 116513193 4432139 2393886..2394905 1 NC_008527.1 Short-chain alcohol dehydrogenase 2394905 4432139 LACR_2559 Lactococcus lactis subsp. cremoris SK11 Short-chain alcohol dehydrogenase YP_812100.1 2393886 D 272622 CDS YP_812101.1 116513194 4432140 2395124..2395210 1 NC_008527.1 hypothetical protein 2395210 4432140 LACR_2560 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812101.1 2395124 D 272622 CDS YP_812102.1 116513195 4432569 2395207..2395911 1 NC_008527.1 metal-dependent membrane protease 2395911 4432569 LACR_2561 Lactococcus lactis subsp. cremoris SK11 metal-dependent membrane protease YP_812102.1 2395207 D 272622 CDS YP_812103.1 116513196 4432570 2395935..2396390 1 NC_008527.1 hypothetical protein 2396390 4432570 LACR_2562 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812103.1 2395935 D 272622 CDS YP_812104.1 116513197 4432246 complement(2402572..2405292) 1 NC_008527.1 hypothetical protein 2405292 4432246 LACR_2573 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812104.1 2402572 R 272622 CDS YP_812105.1 116513198 4432247 complement(2405296..2407374) 1 NC_008527.1 adenine specific DNA methylase Mod 2407374 4432247 LACR_2574 Lactococcus lactis subsp. cremoris SK11 adenine specific DNA methylase Mod YP_812105.1 2405296 R 272622 CDS YP_812106.1 116513199 4432248 complement(2407475..2407954) 1 NC_008527.1 hypothetical protein 2407954 4432248 LACR_2575 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812106.1 2407475 R 272622 CDS YP_812107.1 116513200 4432249 complement(2408065..2409291) 1 NC_008527.1 hypothetical protein 2409291 4432249 LACR_2576 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812107.1 2408065 R 272622 CDS YP_812108.1 116513201 4432250 2409461..2409742 1 NC_008527.1 hypothetical protein 2409742 4432250 LACR_2577 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812108.1 2409461 D 272622 CDS YP_812109.1 116513202 4432251 2409765..2410106 1 NC_008527.1 hypothetical protein 2410106 4432251 LACR_2578 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812109.1 2409765 D 272622 CDS YP_812110.1 116513203 4432252 2410099..2411451 1 NC_008527.1 DNA segregation ATPase FtsK/SpoIIIE related protein 2411451 4432252 LACR_2579 Lactococcus lactis subsp. cremoris SK11 DNA segregation ATPase FtsK/SpoIIIE related protein YP_812110.1 2410099 D 272622 CDS YP_812111.1 116513204 4432253 2411729..2413219 1 NC_008527.1 plasmid replication protein Rep and AAA-class ATPase domain 2413219 4432253 LACR_2580 Lactococcus lactis subsp. cremoris SK11 plasmid replication protein Rep and AAA-class ATPase domain YP_812111.1 2411729 D 272622 CDS YP_812112.1 116513205 4432254 2413453..2413644 1 NC_008527.1 hypothetical protein 2413644 4432254 LACR_2581 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812112.1 2413453 D 272622 CDS YP_812113.1 116513206 4432255 2413736..2414785 1 NC_008527.1 integrase 2414785 4432255 LACR_2582 Lactococcus lactis subsp. cremoris SK11 integrase YP_812113.1 2413736 D 272622 CDS YP_812114.1 116513207 4432256 complement(2414848..2415240) 1 NC_008527.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 2415240 rpsI 4432256 rpsI Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S9 YP_812114.1 2414848 R 272622 CDS YP_812115.1 116513208 4432257 complement(2415260..2415706) 1 NC_008527.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 2415706 rplM 4432257 rplM Lactococcus lactis subsp. cremoris SK11 50S ribosomal protein L13 YP_812115.1 2415260 R 272622 CDS YP_812116.1 116513209 4432258 2416105..2417175 1 NC_008527.1 hypothetical protein 2417175 4432258 LACR_2585 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812116.1 2416105 D 272622 CDS YP_812117.1 116513210 4433360 2417191..2417862 1 NC_008527.1 peptide ABC transporter ATPase 2417862 4433360 LACR_2586 Lactococcus lactis subsp. cremoris SK11 peptide ABC transporter ATPase YP_812117.1 2417191 D 272622 CDS YP_812118.1 116513211 4433361 2418009..2418887 1 NC_008527.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 2418887 4433361 LACR_2587 Lactococcus lactis subsp. cremoris SK11 ribonuclease HIII YP_812118.1 2418009 D 272622 CDS YP_812119.1 116513212 4433362 2418899..2419525 1 NC_008527.1 signal peptidase 2419525 4433362 LACR_2588 Lactococcus lactis subsp. cremoris SK11 signal peptidase YP_812119.1 2418899 D 272622 CDS YP_812120.1 116513213 4433363 complement(2419503..2419583) 1 NC_008527.1 hypothetical protein 2419583 4433363 LACR_2589 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812120.1 2419503 R 272622 CDS YP_812121.1 116513214 4433364 complement(2419573..2420388) 1 NC_008527.1 pur operon repressor 2420388 4433364 LACR_2590 Lactococcus lactis subsp. cremoris SK11 pur operon repressor YP_812121.1 2419573 R 272622 CDS YP_812122.1 116513215 4433365 complement(2420676..2420963) 1 NC_008527.1 hypothetical protein 2420963 4433365 LACR_2591 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812122.1 2420676 R 272622 CDS YP_812123.1 116513216 4433366 complement(2420909..2421643) 1 NC_008527.1 hypothetical protein 2421643 4433366 LACR_2592 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812123.1 2420909 R 272622 CDS YP_812124.1 116513217 4433367 complement(2421646..2423073) 1 NC_008527.1 hypothetical protein 2423073 4433367 LACR_2593 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812124.1 2421646 R 272622 CDS YP_812125.1 116513218 4433368 complement(2423073..2423336) 1 NC_008527.1 prenylated Rab acceptor 1 related protein 2423336 4433368 LACR_2594 Lactococcus lactis subsp. cremoris SK11 prenylated Rab acceptor 1 related protein YP_812125.1 2423073 R 272622 CDS YP_812126.1 116513219 4433370 complement(2426084..2426551) 1 NC_008527.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 2426551 4433370 LACR_2596 Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S7 YP_812126.1 2426084 R 272622 CDS YP_812127.1 116513220 4433371 complement(2426570..2426983) 1 NC_008527.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 2426983 rpsL 4433371 rpsL Lactococcus lactis subsp. cremoris SK11 30S ribosomal protein S12 YP_812127.1 2426570 R 272622 CDS YP_812128.1 116513221 4433372 complement(2427379..2427540) 1 NC_008527.1 hypothetical protein 2427540 4433372 LACR_2598 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812128.1 2427379 R 272622 CDS YP_812129.1 116513222 4433373 complement(2427897..2428148) 1 NC_008527.1 hypothetical protein 2428148 4433373 LACR_2599 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812129.1 2427897 R 272622 CDS YP_812130.1 116513223 4433374 2428576..2429880 1 NC_008527.1 D,D-carboxypeptidase PBP3 2429880 4433374 LACR_2600 Lactococcus lactis subsp. cremoris SK11 D,D-carboxypeptidase PBP3 YP_812130.1 2428576 D 272622 CDS YP_812131.1 116513224 4433375 complement(2429955..2430740) 1 NC_008527.1 putative glucose uptake permease 2430740 4433375 LACR_2601 Lactococcus lactis subsp. cremoris SK11 putative glucose uptake permease YP_812131.1 2429955 R 272622 CDS YP_812132.1 116513225 4433376 complement(2430967..2431602) 1 NC_008527.1 hypothetical protein 2431602 4433376 LACR_2602 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812132.1 2430967 R 272622 CDS YP_812133.1 116513226 4433434 complement(2431746..2432687) 1 NC_008527.1 radical SAM protein 2432687 4433434 LACR_2603 Lactococcus lactis subsp. cremoris SK11 radical SAM protein YP_812133.1 2431746 R 272622 CDS YP_812134.1 116513227 4433441 complement(2438470..2438565) 1 NC_008527.1 hypothetical protein 2438565 4433441 LACR_2610 Lactococcus lactis subsp. cremoris SK11 hypothetical protein YP_812134.1 2438470 R 272622 CDS