-- dump date   	20140619_125101
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
714313000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
714313000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
714313000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313000004	Walker A motif; other site
714313000005	ATP binding site [chemical binding]; other site
714313000006	Walker B motif; other site
714313000007	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
714313000008	arginine finger; other site
714313000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
714313000010	DnaA box-binding interface [nucleotide binding]; other site
714313000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
714313000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
714313000013	putative DNA binding surface [nucleotide binding]; other site
714313000014	dimer interface [polypeptide binding]; other site
714313000015	beta-clamp/clamp loader binding surface; other site
714313000016	beta-clamp/translesion DNA polymerase binding surface; other site
714313000017	S4 domain protein YaaA; Region: YaaA_near_RecF; TIGR02988
714313000018	recombination protein F; Reviewed; Region: recF; PRK00064
714313000019	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
714313000020	Walker A/P-loop; other site
714313000021	ATP binding site [chemical binding]; other site
714313000022	Q-loop/lid; other site
714313000023	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313000024	ABC transporter signature motif; other site
714313000025	Walker B; other site
714313000026	D-loop; other site
714313000027	H-loop/switch region; other site
714313000028	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
714313000029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
714313000030	Mg2+ binding site [ion binding]; other site
714313000031	G-X-G motif; other site
714313000032	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
714313000033	anchoring element; other site
714313000034	dimer interface [polypeptide binding]; other site
714313000035	ATP binding site [chemical binding]; other site
714313000036	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
714313000037	active site
714313000038	putative metal-binding site [ion binding]; other site
714313000039	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
714313000040	DNA gyrase subunit A; Validated; Region: PRK05560
714313000041	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
714313000042	CAP-like domain; other site
714313000043	active site
714313000044	primary dimer interface [polypeptide binding]; other site
714313000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
714313000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
714313000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
714313000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
714313000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
714313000050	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
714313000051	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
714313000052	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
714313000053	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
714313000054	dimer interface [polypeptide binding]; other site
714313000055	ssDNA binding site [nucleotide binding]; other site
714313000056	tetramer (dimer of dimers) interface [polypeptide binding]; other site
714313000057	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
714313000058	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
714313000059	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
714313000060	DHH family; Region: DHH; pfam01368
714313000061	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
714313000062	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
714313000063	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
714313000064	replicative DNA helicase; Region: DnaB; TIGR00665
714313000065	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
714313000066	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
714313000067	Walker A motif; other site
714313000068	ATP binding site [chemical binding]; other site
714313000069	Walker B motif; other site
714313000070	DNA binding loops [nucleotide binding]
714313000071	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
714313000072	EamA-like transporter family; Region: EamA; pfam00892
714313000073	EamA-like transporter family; Region: EamA; pfam00892
714313000074	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
714313000075	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
714313000076	active site
714313000077	phosphorylation site [posttranslational modification]
714313000078	intermolecular recognition site; other site
714313000079	dimerization interface [polypeptide binding]; other site
714313000080	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
714313000081	DNA binding site [nucleotide binding]
714313000082	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
714313000083	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
714313000084	dimerization interface [polypeptide binding]; other site
714313000085	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
714313000086	putative active site [active]
714313000087	heme pocket [chemical binding]; other site
714313000088	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
714313000089	dimer interface [polypeptide binding]; other site
714313000090	phosphorylation site [posttranslational modification]
714313000091	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
714313000092	ATP binding site [chemical binding]; other site
714313000093	Mg2+ binding site [ion binding]; other site
714313000094	G-X-G motif; other site
714313000095	YycH protein; Region: YycH; pfam07435
714313000096	YycH protein; Region: YycI; pfam09648
714313000097	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
714313000098	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
714313000099	YibE/F-like protein; Region: YibE_F; pfam07907
714313000100	YibE/F-like protein; Region: YibE_F; pfam07907
714313000101	hypothetical protein; Provisional; Region: PRK10621
714313000102	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
714313000103	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
714313000104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000105	Major Facilitator Superfamily; Region: MFS_1; pfam07690
714313000106	putative substrate translocation pore; other site
714313000107	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
714313000108	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
714313000109	Walker A/P-loop; other site
714313000110	ATP binding site [chemical binding]; other site
714313000111	Q-loop/lid; other site
714313000112	ABC transporter signature motif; other site
714313000113	Walker B; other site
714313000114	D-loop; other site
714313000115	H-loop/switch region; other site
714313000116	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
714313000117	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
714313000118	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
714313000119	Walker A/P-loop; other site
714313000120	ATP binding site [chemical binding]; other site
714313000121	Q-loop/lid; other site
714313000122	ABC transporter signature motif; other site
714313000123	Walker B; other site
714313000124	D-loop; other site
714313000125	H-loop/switch region; other site
714313000126	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
714313000127	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
714313000128	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313000129	dimer interface [polypeptide binding]; other site
714313000130	conserved gate region; other site
714313000131	putative PBP binding loops; other site
714313000132	ABC-ATPase subunit interface; other site
714313000133	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SapC; COG4171
714313000134	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313000135	putative PBP binding loops; other site
714313000136	ABC-ATPase subunit interface; other site
714313000137	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
714313000138	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
714313000139	peptide binding site [polypeptide binding]; other site
714313000140	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
714313000141	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
714313000142	Zn binding site [ion binding]; other site
714313000143	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
714313000144	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
714313000145	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
714313000146	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
714313000147	active site
714313000148	metal binding site [ion binding]; metal-binding site
714313000149	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
714313000150	benzoate transport; Region: 2A0115; TIGR00895
714313000151	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000152	putative substrate translocation pore; other site
714313000153	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
714313000154	hypothetical protein; Provisional; Region: PRK10621
714313000155	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
714313000156	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
714313000157	Predicted flavoprotein [General function prediction only]; Region: COG0431
714313000158	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
714313000159	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
714313000160	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
714313000161	aspartate kinase; Reviewed; Region: PRK09034
714313000162	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
714313000163	putative catalytic residues [active]
714313000164	putative nucleotide binding site [chemical binding]; other site
714313000165	putative aspartate binding site [chemical binding]; other site
714313000166	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
714313000167	allosteric regulatory residue; other site
714313000168	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
714313000169	diaminopimelate decarboxylase; Region: lysA; TIGR01048
714313000170	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
714313000171	active site
714313000172	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
714313000173	substrate binding site [chemical binding]; other site
714313000174	catalytic residues [active]
714313000175	dimer interface [polypeptide binding]; other site
714313000176	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
714313000177	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
714313000178	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
714313000179	active site
714313000180	trimer interface [polypeptide binding]; other site
714313000181	substrate binding site [chemical binding]; other site
714313000182	CoA binding site [chemical binding]; other site
714313000183	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
714313000184	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
714313000185	metal binding site [ion binding]; metal-binding site
714313000186	putative dimer interface [polypeptide binding]; other site
714313000187	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
714313000188	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
714313000189	dimer interface [polypeptide binding]; other site
714313000190	active site
714313000191	catalytic residue [active]
714313000192	dihydrodipicolinate reductase; Provisional; Region: PRK00048
714313000193	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
714313000194	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
714313000195	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
714313000196	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
714313000197	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
714313000198	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
714313000199	catalytic triad [active]
714313000200	catalytic triad [active]
714313000201	oxyanion hole [active]
714313000202	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
714313000203	amino acid transporter; Region: 2A0306; TIGR00909
714313000204	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
714313000205	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
714313000206	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
714313000207	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
714313000208	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
714313000209	Walker A/P-loop; other site
714313000210	ATP binding site [chemical binding]; other site
714313000211	Q-loop/lid; other site
714313000212	ABC transporter signature motif; other site
714313000213	Walker B; other site
714313000214	D-loop; other site
714313000215	H-loop/switch region; other site
714313000216	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
714313000217	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
714313000218	FtsX-like permease family; Region: FtsX; pfam02687
714313000219	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
714313000220	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
714313000221	catalytic triad [active]
714313000222	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
714313000223	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
714313000224	active site
714313000225	Int/Topo IB signature motif; other site
714313000226	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
714313000227	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
714313000228	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
714313000229	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
714313000230	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
714313000231	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
714313000232	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
714313000233	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
714313000234	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
714313000235	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
714313000236	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
714313000237	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
714313000238	TrkA-N domain; Region: TrkA_N; pfam02254
714313000239	TrkA-C domain; Region: TrkA_C; pfam02080
714313000240	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
714313000241	PemK-like protein; Region: PemK; pfam02452
714313000242	multicopper oxidase; Provisional; Region: PRK10965
714313000243	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
714313000244	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
714313000245	Predicted membrane protein [Function unknown]; Region: COG3601
714313000246	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
714313000247	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
714313000248	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
714313000249	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
714313000250	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
714313000251	DNA binding residues [nucleotide binding]
714313000252	putative dimer interface [polypeptide binding]; other site
714313000253	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
714313000254	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
714313000255	nudix motif; other site
714313000256	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
714313000257	D-lactate dehydrogenase; Validated; Region: PRK08605
714313000258	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
714313000259	homodimer interface [polypeptide binding]; other site
714313000260	ligand binding site [chemical binding]; other site
714313000261	NAD binding site [chemical binding]; other site
714313000262	catalytic site [active]
714313000263	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
714313000264	pyridoxal 5'-phosphate binding site [chemical binding]; other site
714313000265	homodimer interface [polypeptide binding]; other site
714313000266	catalytic residue [active]
714313000267	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
714313000268	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
714313000269	Coenzyme A binding pocket [chemical binding]; other site
714313000270	Transcriptional regulators [Transcription]; Region: MarR; COG1846
714313000271	MarR family; Region: MarR_2; pfam12802
714313000272	Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane]; Region: TnrB3; COG3559
714313000273	peptidase T; Region: peptidase-T; TIGR01882
714313000274	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
714313000275	metal binding site [ion binding]; metal-binding site
714313000276	dimer interface [polypeptide binding]; other site
714313000277	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
714313000278	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
714313000279	Domain of unknown function (DU1801); Region: DUF1801; cl17490
714313000280	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000281	Homeodomain-like domain; Region: HTH_23; cl17451
714313000282	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000283	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
714313000284	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
714313000285	Na binding site [ion binding]; other site
714313000286	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
714313000287	CAAX protease self-immunity; Region: Abi; pfam02517
714313000288	Protein of unknown function (DUF1516); Region: DUF1516; cl11654
714313000289	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
714313000290	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
714313000291	intersubunit interface [polypeptide binding]; other site
714313000292	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
714313000293	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
714313000294	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
714313000295	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
714313000296	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
714313000297	Walker A/P-loop; other site
714313000298	ATP binding site [chemical binding]; other site
714313000299	Q-loop/lid; other site
714313000300	ABC transporter signature motif; other site
714313000301	Walker B; other site
714313000302	D-loop; other site
714313000303	H-loop/switch region; other site
714313000304	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
714313000305	Walker A/P-loop; other site
714313000306	ATP binding site [chemical binding]; other site
714313000307	ABC transporter; Region: ABC_tran; pfam00005
714313000308	Q-loop/lid; other site
714313000309	ABC transporter signature motif; other site
714313000310	Walker B; other site
714313000311	D-loop; other site
714313000312	H-loop/switch region; other site
714313000313	Predicted transcriptional regulators [Transcription]; Region: COG1733
714313000314	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
714313000315	Predicted transcriptional regulators [Transcription]; Region: COG1733
714313000316	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313000317	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313000318	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313000319	Probable transposase; Region: OrfB_IS605; pfam01385
714313000320	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313000321	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
714313000322	putative substrate translocation pore; other site
714313000323	Predicted transcriptional regulators [Transcription]; Region: COG1733
714313000324	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
714313000325	recombinase A; Provisional; Region: recA; PRK09354
714313000326	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
714313000327	hexamer interface [polypeptide binding]; other site
714313000328	Walker A motif; other site
714313000329	ATP binding site [chemical binding]; other site
714313000330	Walker B motif; other site
714313000331	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
714313000332	Predicted membrane protein [Function unknown]; Region: COG4392
714313000333	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
714313000334	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
714313000335	Coenzyme A binding pocket [chemical binding]; other site
714313000336	putative acyltransferase; Provisional; Region: PRK05790
714313000337	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
714313000338	dimer interface [polypeptide binding]; other site
714313000339	active site
714313000340	potential frameshift: common BLAST hit: gi|254555475|ref|YP_003061892.1| transaminase
714313000341	transaminase; Reviewed; Region: PRK08068
714313000342	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
714313000343	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
714313000344	pyridoxal 5'-phosphate binding site [chemical binding]; other site
714313000345	homodimer interface [polypeptide binding]; other site
714313000346	catalytic residue [active]
714313000347	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
714313000348	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
714313000349	Walker A/P-loop; other site
714313000350	ATP binding site [chemical binding]; other site
714313000351	Q-loop/lid; other site
714313000352	ABC transporter signature motif; other site
714313000353	Walker B; other site
714313000354	D-loop; other site
714313000355	H-loop/switch region; other site
714313000356	NIL domain; Region: NIL; pfam09383
714313000357	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313000358	dimer interface [polypeptide binding]; other site
714313000359	conserved gate region; other site
714313000360	ABC-ATPase subunit interface; other site
714313000361	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000362	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000363	putative transposase OrfB; Reviewed; Region: PHA02517
714313000364	HTH-like domain; Region: HTH_21; pfam13276
714313000365	Integrase core domain; Region: rve; pfam00665
714313000366	Integrase core domain; Region: rve_2; pfam13333
714313000367	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Region: Tas; COG0667
714313000368	Protein of unknown function, DUF488; Region: DUF488; cl01246
714313000369	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313000370	ABC transporter signature motif; other site
714313000371	Walker B; other site
714313000372	D-loop; other site
714313000373	H-loop/switch region; other site
714313000374	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313000375	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313000376	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313000377	Probable transposase; Region: OrfB_IS605; pfam01385
714313000378	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313000379	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
714313000380	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
714313000381	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
714313000382	acetoin reductase; Validated; Region: PRK08643
714313000383	NAD(P) binding site [chemical binding]; other site
714313000384	active site
714313000385	amino acid transporter; Region: 2A0306; TIGR00909
714313000386	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
714313000387	4-aminobutyrate aminotransferase; Provisional; Region: PRK08593
714313000388	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
714313000389	inhibitor-cofactor binding pocket; inhibition site
714313000390	pyridoxal 5'-phosphate binding site [chemical binding]; other site
714313000391	catalytic residue [active]
714313000392	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000393	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
714313000394	putative substrate translocation pore; other site
714313000395	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000396	Major Facilitator Superfamily; Region: MFS_1; pfam07690
714313000397	putative substrate translocation pore; other site
714313000398	maltose phosphorylase; Provisional; Region: PRK13807
714313000399	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
714313000400	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
714313000401	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
714313000402	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
714313000403	active site
714313000404	catalytic residues [active]
714313000405	beta-phosphoglucomutase; Region: bPGM; TIGR01990
714313000406	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313000407	motif II; other site
714313000408	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000409	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000410	putative transposase OrfB; Reviewed; Region: PHA02517
714313000411	HTH-like domain; Region: HTH_21; pfam13276
714313000412	Integrase core domain; Region: rve; pfam00665
714313000413	Integrase core domain; Region: rve_2; pfam13333
714313000414	INT_SG3, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 3, catalytic domain. The CD contains various predicted bacterial and phage integrase/recombinase sequences for which not much experimental characterization is available; Region: INT_SG3_C; cd01186
714313000415	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
714313000416	Int/Topo IB signature motif; other site
714313000417	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000418	putative transposase OrfB; Reviewed; Region: PHA02517
714313000419	HTH-like domain; Region: HTH_21; pfam13276
714313000420	Integrase core domain; Region: rve; pfam00665
714313000421	Integrase core domain; Region: rve_2; pfam13333
714313000422	Bacterial sugar transferase; Region: Bac_transf; pfam02397
714313000423	Bacterial sugar transferase; Region: Bac_transf; cl00939
714313000424	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
714313000425	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
714313000426	Capsular polysaccharide synthesis protein; Region: Caps_synth; pfam05704
714313000427	Transposase, Mutator family; Region: Transposase_mut; pfam00872
714313000428	MULE transposase domain; Region: MULE; pfam10551
714313000429	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
714313000430	active site
714313000431	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
714313000432	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
714313000433	active site
714313000434	DDE domain; Region: DDE_Tnp_IS240; pfam13610
714313000435	Integrase core domain; Region: rve; pfam00665
714313000436	Integrase core domain; Region: rve_3; cl15866
714313000437	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000438	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000439	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000440	Integrase core domain; Region: rve; pfam00665
714313000441	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
714313000442	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
714313000443	Ca binding site [ion binding]; other site
714313000444	active site
714313000445	catalytic site [active]
714313000446	Major Facilitator Superfamily; Region: MFS_1; pfam07690
714313000447	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000448	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000449	Transposase; Region: HTH_Tnp_1; pfam01527
714313000450	GMP synthase; Reviewed; Region: guaA; PRK00074
714313000451	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
714313000452	AMP/PPi binding site [chemical binding]; other site
714313000453	candidate oxyanion hole; other site
714313000454	catalytic triad [active]
714313000455	potential glutamine specificity residues [chemical binding]; other site
714313000456	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
714313000457	ATP Binding subdomain [chemical binding]; other site
714313000458	Ligand Binding sites [chemical binding]; other site
714313000459	Dimerization subdomain; other site
714313000460	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK06843
714313000461	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
714313000462	active site
714313000463	histidyl-tRNA synthetase; Region: hisS; TIGR00442
714313000464	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
714313000465	dimer interface [polypeptide binding]; other site
714313000466	motif 1; other site
714313000467	active site
714313000468	motif 2; other site
714313000469	motif 3; other site
714313000470	HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for...; Region: HGTP_anticodon; cl00266
714313000471	anticodon binding site; other site
714313000472	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
714313000473	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313000474	dimer interface [polypeptide binding]; other site
714313000475	conserved gate region; other site
714313000476	putative PBP binding loops; other site
714313000477	ABC-ATPase subunit interface; other site
714313000478	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
714313000479	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313000480	Walker A/P-loop; other site
714313000481	ATP binding site [chemical binding]; other site
714313000482	Q-loop/lid; other site
714313000483	ABC transporter signature motif; other site
714313000484	Walker B; other site
714313000485	D-loop; other site
714313000486	H-loop/switch region; other site
714313000487	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
714313000488	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
714313000489	substrate binding pocket [chemical binding]; other site
714313000490	membrane-bound complex binding site; other site
714313000491	hinge residues; other site
714313000492	Homeodomain-like domain; Region: HTH_23; cl17451
714313000493	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000494	HTH-like domain; Region: HTH_21; pfam13276
714313000495	Integrase core domain; Region: rve; pfam00665
714313000496	Integrase core domain; Region: rve_2; pfam13333
714313000497	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
714313000498	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
714313000499	FAD binding site [chemical binding]; other site
714313000500	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313000501	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313000502	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313000503	Probable transposase; Region: OrfB_IS605; pfam01385
714313000504	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313000505	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
714313000506	EDD domain protein, DegV family; Region: DegV; TIGR00762
714313000507	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
714313000508	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000509	Major Facilitator Superfamily; Region: MFS_1; pfam07690
714313000510	putative substrate translocation pore; other site
714313000511	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
714313000512	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
714313000513	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
714313000514	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
714313000515	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313000516	Walker A/P-loop; other site
714313000517	ATP binding site [chemical binding]; other site
714313000518	Q-loop/lid; other site
714313000519	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313000520	ABC transporter signature motif; other site
714313000521	Walker B; other site
714313000522	D-loop; other site
714313000523	H-loop/switch region; other site
714313000524	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313000525	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
714313000526	Walker A/P-loop; other site
714313000527	ATP binding site [chemical binding]; other site
714313000528	Q-loop/lid; other site
714313000529	ABC transporter signature motif; other site
714313000530	Walker B; other site
714313000531	D-loop; other site
714313000532	H-loop/switch region; other site
714313000533	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
714313000534	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
714313000535	substrate binding pocket [chemical binding]; other site
714313000536	membrane-bound complex binding site; other site
714313000537	hinge residues; other site
714313000538	NrdI Flavodoxin like; Region: Flavodoxin_NdrI; cl17293
714313000539	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
714313000540	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
714313000541	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
714313000542	Domain of unknown function DUF21; Region: DUF21; pfam01595
714313000543	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
714313000544	Transporter associated domain; Region: CorC_HlyC; smart01091
714313000545	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
714313000546	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
714313000547	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313000548	motif II; other site
714313000549	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313000550	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313000551	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313000552	Probable transposase; Region: OrfB_IS605; pfam01385
714313000553	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313000554	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
714313000555	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
714313000556	putative catalytic cysteine [active]
714313000557	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
714313000558	putative active site [active]
714313000559	metal binding site [ion binding]; metal-binding site
714313000560	Transcriptional regulator [Transcription]; Region: LysR; COG0583
714313000561	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
714313000562	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
714313000563	dimerization interface [polypeptide binding]; other site
714313000564	malate dehydrogenase; Provisional; Region: PRK13529
714313000565	Malic enzyme, N-terminal domain; Region: malic; pfam00390
714313000566	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
714313000567	NAD(P) binding site [chemical binding]; other site
714313000568	Membrane transport protein; Region: Mem_trans; cl09117
714313000569	DDE domain; Region: DDE_Tnp_IS240; pfam13610
714313000570	Integrase core domain; Region: rve; pfam00665
714313000571	Integrase core domain; Region: rve_3; pfam13683
714313000572	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000573	Transposase; Region: HTH_Tnp_1; pfam01527
714313000574	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
714313000575	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
714313000576	active site
714313000577	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
714313000578	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
714313000579	Resolvase, N terminal domain; Region: Resolvase; pfam00239
714313000580	Homeodomain-like domain; Region: HTH_23; pfam13384
714313000581	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
714313000582	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
714313000583	Zn2+ binding site [ion binding]; other site
714313000584	Mg2+ binding site [ion binding]; other site
714313000585	K+ potassium transporter; Region: K_trans; pfam02705
714313000586	Cadmium resistance transporter; Region: Cad; pfam03596
714313000587	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
714313000588	dimerization interface [polypeptide binding]; other site
714313000589	putative DNA binding site [nucleotide binding]; other site
714313000590	putative Zn2+ binding site [ion binding]; other site
714313000591	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
714313000592	putative deacylase active site [active]
714313000593	manganese transport protein MntH; Reviewed; Region: PRK00701
714313000594	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
714313000595	putative transposase OrfB; Reviewed; Region: PHA02517
714313000596	HTH-like domain; Region: HTH_21; pfam13276
714313000597	Integrase core domain; Region: rve; pfam00665
714313000598	Integrase core domain; Region: rve_2; pfam13333
714313000599	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
714313000600	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
714313000601	DNA-binding site [nucleotide binding]; DNA binding site
714313000602	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
714313000603	putative phosphoketolase; Provisional; Region: PRK05261
714313000604	XFP N-terminal domain; Region: XFP_N; pfam09364
714313000605	XFP C-terminal domain; Region: XFP_C; pfam09363
714313000606	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
714313000607	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
714313000608	active site
714313000609	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
714313000610	Ligand Binding Site [chemical binding]; other site
714313000611	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
714313000612	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
714313000613	pyridoxal 5'-phosphate binding site [chemical binding]; other site
714313000614	homodimer interface [polypeptide binding]; other site
714313000615	catalytic residue [active]
714313000616	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
714313000617	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
714313000618	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK14106
714313000619	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
714313000620	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
714313000621	non-specific DNA binding site [nucleotide binding]; other site
714313000622	salt bridge; other site
714313000623	sequence-specific DNA binding site [nucleotide binding]; other site
714313000624	phosphodiesterase; Provisional; Region: PRK12704
714313000625	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
714313000626	Zn2+ binding site [ion binding]; other site
714313000627	Mg2+ binding site [ion binding]; other site
714313000628	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
714313000629	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
714313000630	active site
714313000631	metal binding site [ion binding]; metal-binding site
714313000632	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
714313000633	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
714313000634	ArsC family; Region: ArsC; pfam03960
714313000635	putative catalytic residues [active]
714313000636	thiol/disulfide switch; other site
714313000637	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
714313000638	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313000639	active site
714313000640	motif I; other site
714313000641	motif II; other site
714313000642	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000643	Transposase; Region: HTH_Tnp_1; pfam01527
714313000644	NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These...; Region: nuc_hydro_CaPnhB; cd02650
714313000645	active site
714313000646	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
714313000647	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
714313000648	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
714313000649	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
714313000650	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
714313000651	Sulfatase; Region: Sulfatase; pfam00884
714313000652	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313000653	catalytic core [active]
714313000654	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313000655	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
714313000656	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
714313000657	DNA binding residues [nucleotide binding]
714313000658	putative dimer interface [polypeptide binding]; other site
714313000659	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
714313000660	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
714313000661	Cl binding site [ion binding]; other site
714313000662	oligomer interface [polypeptide binding]; other site
714313000663	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
714313000664	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
714313000665	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
714313000666	catalytic residues [active]
714313000667	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
714313000668	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
714313000669	putative transposase OrfB; Reviewed; Region: PHA02517
714313000670	HTH-like domain; Region: HTH_21; pfam13276
714313000671	Integrase core domain; Region: rve; pfam00665
714313000672	Integrase core domain; Region: rve_3; pfam13683
714313000673	Transposase; Region: HTH_Tnp_1; pfam01527
714313000674	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000675	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
714313000676	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
714313000677	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
714313000678	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
714313000679	active site
714313000680	HIGH motif; other site
714313000681	dimer interface [polypeptide binding]; other site
714313000682	KMSKS motif; other site
714313000683	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
714313000684	RNA binding surface [nucleotide binding]; other site
714313000685	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
714313000686	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
714313000687	glycerol kinase; Provisional; Region: glpK; PRK00047
714313000688	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
714313000689	N- and C-terminal domain interface [polypeptide binding]; other site
714313000690	active site
714313000691	MgATP binding site [chemical binding]; other site
714313000692	catalytic site [active]
714313000693	metal binding site [ion binding]; metal-binding site
714313000694	glycerol binding site [chemical binding]; other site
714313000695	homotetramer interface [polypeptide binding]; other site
714313000696	homodimer interface [polypeptide binding]; other site
714313000697	FBP binding site [chemical binding]; other site
714313000698	protein IIAGlc interface [polypeptide binding]; other site
714313000699	Sugar transport protein; Region: Sugar_transport; pfam06800
714313000700	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
714313000701	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
714313000702	TRAM domain; Region: TRAM; pfam01938
714313000703	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313000704	S-adenosylmethionine binding site [chemical binding]; other site
714313000705	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
714313000706	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
714313000707	Walker A/P-loop; other site
714313000708	ATP binding site [chemical binding]; other site
714313000709	Q-loop/lid; other site
714313000710	ABC transporter signature motif; other site
714313000711	Walker B; other site
714313000712	D-loop; other site
714313000713	H-loop/switch region; other site
714313000714	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
714313000715	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
714313000716	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
714313000717	putative NAD(P) binding site [chemical binding]; other site
714313000718	amino acid transporter; Region: 2A0306; TIGR00909
714313000719	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
714313000720	Predicted membrane protein [Function unknown]; Region: COG2364
714313000721	L-threonine dehydrogenase; Region: threonine_DH_like; cd08234
714313000722	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
714313000723	putative NAD(P) binding site [chemical binding]; other site
714313000724	catalytic Zn binding site [ion binding]; other site
714313000725	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
714313000726	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
714313000727	substrate binding site [chemical binding]; other site
714313000728	dimer interface [polypeptide binding]; other site
714313000729	ATP binding site [chemical binding]; other site
714313000730	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
714313000731	tetramer (dimer of dimers) interface [polypeptide binding]; other site
714313000732	active site
714313000733	dimer interface [polypeptide binding]; other site
714313000734	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
714313000735	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
714313000736	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
714313000737	Coenzyme A binding pocket [chemical binding]; other site
714313000738	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
714313000739	active site
714313000740	EDD domain protein, DegV family; Region: DegV; TIGR00762
714313000741	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
714313000742	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
714313000743	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
714313000744	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
714313000745	active site
714313000746	Zn binding site [ion binding]; other site
714313000747	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
714313000748	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
714313000749	Predicted membrane protein [Function unknown]; Region: COG2323
714313000750	Protein of unknown function (DUF3290); Region: DUF3290; pfam11694
714313000751	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
714313000752	metal binding site 2 [ion binding]; metal-binding site
714313000753	putative DNA binding helix; other site
714313000754	metal binding site 1 [ion binding]; metal-binding site
714313000755	dimer interface [polypeptide binding]; other site
714313000756	structural Zn2+ binding site [ion binding]; other site
714313000757	DEAD_2; Region: DEAD_2; pfam06733
714313000758	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
714313000759	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
714313000760	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
714313000761	active site
714313000762	homotetramer interface [polypeptide binding]; other site
714313000763	homodimer interface [polypeptide binding]; other site
714313000764	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
714313000765	Ligand Binding Site [chemical binding]; other site
714313000766	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
714313000767	substrate binding site [chemical binding]; other site
714313000768	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
714313000769	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
714313000770	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
714313000771	active site
714313000772	metal binding site [ion binding]; metal-binding site
714313000773	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
714313000774	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313000775	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313000776	ABC transporter; Region: ABC_tran_2; pfam12848
714313000777	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313000778	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
714313000779	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
714313000780	active site
714313000781	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
714313000782	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
714313000783	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
714313000784	Guanylate kinase; Region: Guanylate_kin; pfam00625
714313000785	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
714313000786	active site
714313000787	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
714313000788	Nitronate monooxygenase; Region: NMO; pfam03060
714313000789	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
714313000790	FMN binding site [chemical binding]; other site
714313000791	substrate binding site [chemical binding]; other site
714313000792	putative catalytic residue [active]
714313000793	L-type amino acid transporter; Region: 2A0308; TIGR00911
714313000794	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
714313000795	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
714313000796	HflX GTPase family; Region: HflX; cd01878
714313000797	G1 box; other site
714313000798	GTP/Mg2+ binding site [chemical binding]; other site
714313000799	Switch I region; other site
714313000800	G2 box; other site
714313000801	G3 box; other site
714313000802	Switch II region; other site
714313000803	G4 box; other site
714313000804	G5 box; other site
714313000805	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313000806	catalytic core [active]
714313000807	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313000808	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
714313000809	Part of AAA domain; Region: AAA_19; pfam13245
714313000810	Family description; Region: UvrD_C_2; pfam13538
714313000811	pantothenate kinase; Provisional; Region: PRK05439
714313000812	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
714313000813	ATP-binding site [chemical binding]; other site
714313000814	CoA-binding site [chemical binding]; other site
714313000815	Mg2+-binding site [ion binding]; other site
714313000816	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
714313000817	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
714313000818	Penicillinase repressor; Region: Pencillinase_R; pfam03965
714313000819	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
714313000820	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
714313000821	Soluble P-type ATPase [General function prediction only]; Region: COG4087
714313000822	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
714313000823	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
714313000824	active site
714313000825	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
714313000826	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
714313000827	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
714313000828	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
714313000829	putative transposase OrfB; Reviewed; Region: PHA02517
714313000830	HTH-like domain; Region: HTH_21; pfam13276
714313000831	Integrase core domain; Region: rve; pfam00665
714313000832	Integrase core domain; Region: rve_2; pfam13333
714313000833	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000834	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000835	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313000836	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313000837	Uncharacterized conserved protein [Function unknown]; Region: COG2966
714313000838	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
714313000839	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
714313000840	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
714313000841	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
714313000842	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
714313000843	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
714313000844	phosphate binding site [ion binding]; other site
714313000845	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
714313000846	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
714313000847	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
714313000848	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
714313000849	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
714313000850	active site
714313000851	DEAD-like helicases superfamily; Region: DEXDc; smart00487
714313000852	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
714313000853	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313000854	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313000855	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313000856	Probable transposase; Region: OrfB_IS605; pfam01385
714313000857	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313000858	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
714313000859	Integrase core domain; Region: rve_3; pfam13683
714313000860	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
714313000861	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
714313000862	Cl- selectivity filter; other site
714313000863	Cl- binding residues [ion binding]; other site
714313000864	pore gating glutamate residue; other site
714313000865	dimer interface [polypeptide binding]; other site
714313000866	H+/Cl- coupling transport residue; other site
714313000867	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
714313000868	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
714313000869	Nucleoside recognition; Region: Gate; pfam07670
714313000870	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
714313000871	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
714313000872	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
714313000873	active site
714313000874	tetramer interface [polypeptide binding]; other site
714313000875	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
714313000876	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313000877	S-adenosylmethionine binding site [chemical binding]; other site
714313000878	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
714313000879	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
714313000880	P-loop; other site
714313000881	Magnesium ion binding site [ion binding]; other site
714313000882	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
714313000883	Magnesium ion binding site [ion binding]; other site
714313000884	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
714313000885	ParB-like nuclease domain; Region: ParB; smart00470
714313000886	KorB domain; Region: KorB; pfam08535
714313000887	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
714313000888	GTP-binding protein YchF; Reviewed; Region: PRK09601
714313000889	YchF GTPase; Region: YchF; cd01900
714313000890	G1 box; other site
714313000891	GTP/Mg2+ binding site [chemical binding]; other site
714313000892	Switch I region; other site
714313000893	G2 box; other site
714313000894	Switch II region; other site
714313000895	G3 box; other site
714313000896	G4 box; other site
714313000897	G5 box; other site
714313000898	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
714313000899	Protein of unknown function (DUF1129); Region: DUF1129; cl11555
714313000900	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
714313000901	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
714313000902	active site
714313000903	phosphorylation site [posttranslational modification]
714313000904	intermolecular recognition site; other site
714313000905	dimerization interface [polypeptide binding]; other site
714313000906	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
714313000907	DNA binding site [nucleotide binding]
714313000908	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
714313000909	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
714313000910	dimer interface [polypeptide binding]; other site
714313000911	phosphorylation site [posttranslational modification]
714313000912	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
714313000913	ATP binding site [chemical binding]; other site
714313000914	Mg2+ binding site [ion binding]; other site
714313000915	G-X-G motif; other site
714313000916	AzlC protein; Region: AzlC; pfam03591
714313000917	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
714313000918	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
714313000919	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313000920	catalytic core [active]
714313000921	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313000922	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
714313000923	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000924	putative substrate translocation pore; other site
714313000925	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313000926	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
714313000927	active site
714313000928	catalytic residues [active]
714313000929	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
714313000930	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
714313000931	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
714313000932	Part of AAA domain; Region: AAA_19; pfam13245
714313000933	Family description; Region: UvrD_C_2; pfam13538
714313000934	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
714313000935	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
714313000936	active site
714313000937	HIGH motif; other site
714313000938	dimer interface [polypeptide binding]; other site
714313000939	KMSKS motif; other site
714313000940	exopolyphosphatase; Region: exo_poly_only; TIGR03706
714313000941	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
714313000942	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
714313000943	homodimer interface [polypeptide binding]; other site
714313000944	catalytic residues [active]
714313000945	NAD binding site [chemical binding]; other site
714313000946	substrate binding pocket [chemical binding]; other site
714313000947	flexible flap; other site
714313000948	NAD-dependent deacetylase; Provisional; Region: PRK00481
714313000949	SIR2H: Uncharacterized prokaryotic Sir2 homologs from several gram positive bacterial species and Fusobacteria; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone...; Region: SIR2H; cd01411
714313000950	NAD+ binding site [chemical binding]; other site
714313000951	substrate binding site [chemical binding]; other site
714313000952	putative Zn binding site [ion binding]; other site
714313000953	Protein of unknown function DUF72; Region: DUF72; pfam01904
714313000954	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
714313000955	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
714313000956	active site
714313000957	HIGH motif; other site
714313000958	KMSKS motif; other site
714313000959	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
714313000960	tRNA binding surface [nucleotide binding]; other site
714313000961	anticodon binding site; other site
714313000962	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
714313000963	dimer interface [polypeptide binding]; other site
714313000964	putative tRNA-binding site [nucleotide binding]; other site
714313000965	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
714313000966	active site
714313000967	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
714313000968	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
714313000969	putative active site [active]
714313000970	putative metal binding site [ion binding]; other site
714313000971	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
714313000972	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
714313000973	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313000974	S-adenosylmethionine binding site [chemical binding]; other site
714313000975	Protein of unknown function (DUF1021); Region: DUF1021; cl01852
714313000976	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
714313000977	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
714313000978	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
714313000979	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
714313000980	ABC-ATPase subunit  interface; other site
714313000981	dimer interface [polypeptide binding]; other site
714313000982	putative PBP binding regions; other site
714313000983	pur operon repressor; Provisional; Region: PRK09213
714313000984	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
714313000985	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313000986	active site
714313000987	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
714313000988	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
714313000989	Substrate binding site; other site
714313000990	Mg++ binding site; other site
714313000991	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
714313000992	active site
714313000993	substrate binding site [chemical binding]; other site
714313000994	CoA binding site [chemical binding]; other site
714313000995	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
714313000996	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
714313000997	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313000998	active site
714313000999	sugar phosphate phosphatase; Provisional; Region: PRK10513
714313001000	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313001001	active site
714313001002	motif I; other site
714313001003	motif II; other site
714313001004	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313001005	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
714313001006	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
714313001007	Zn2+ binding site [ion binding]; other site
714313001008	Mg2+ binding site [ion binding]; other site
714313001009	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
714313001010	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
714313001011	CTP synthetase; Validated; Region: pyrG; PRK05380
714313001012	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
714313001013	Catalytic site [active]
714313001014	active site
714313001015	UTP binding site [chemical binding]; other site
714313001016	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
714313001017	active site
714313001018	putative oxyanion hole; other site
714313001019	catalytic triad [active]
714313001020	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
714313001021	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
714313001022	hinge; other site
714313001023	active site
714313001024	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
714313001025	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
714313001026	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
714313001027	drug efflux system protein MdtG; Provisional; Region: PRK09874
714313001028	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313001029	putative substrate translocation pore; other site
714313001030	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
714313001031	Low molecular weight phosphatase family; Region: LMWPc; cd00115
714313001032	active site
714313001033	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313001034	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313001035	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313001036	Probable transposase; Region: OrfB_IS605; pfam01385
714313001037	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313001038	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
714313001039	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
714313001040	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
714313001041	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
714313001042	helicase 45; Provisional; Region: PTZ00424
714313001043	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
714313001044	ATP binding site [chemical binding]; other site
714313001045	Mg++ binding site [ion binding]; other site
714313001046	motif III; other site
714313001047	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313001048	nucleotide binding region [chemical binding]; other site
714313001049	ATP-binding site [chemical binding]; other site
714313001050	alanine racemase; Reviewed; Region: alr; PRK00053
714313001051	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
714313001052	active site
714313001053	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
714313001054	dimer interface [polypeptide binding]; other site
714313001055	substrate binding site [chemical binding]; other site
714313001056	catalytic residues [active]
714313001057	PemK-like protein; Region: PemK; pfam02452
714313001058	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
714313001059	putative active site [active]
714313001060	catalytic residue [active]
714313001061	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
714313001062	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
714313001063	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
714313001064	ATP binding site [chemical binding]; other site
714313001065	putative Mg++ binding site [ion binding]; other site
714313001066	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313001067	nucleotide binding region [chemical binding]; other site
714313001068	ATP-binding site [chemical binding]; other site
714313001069	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
714313001070	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
714313001071	RNA binding surface [nucleotide binding]; other site
714313001072	hypothetical protein; Provisional; Region: PRK08582
714313001073	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
714313001074	RNA binding site [nucleotide binding]; other site
714313001075	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
714313001076	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
714313001077	Ligand Binding Site [chemical binding]; other site
714313001078	TilS substrate C-terminal domain; Region: TilS_C; smart00977
714313001079	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313001080	active site
714313001081	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
714313001082	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313001083	Walker A motif; other site
714313001084	ATP binding site [chemical binding]; other site
714313001085	Walker B motif; other site
714313001086	arginine finger; other site
714313001087	Peptidase family M41; Region: Peptidase_M41; pfam01434
714313001088	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
714313001089	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
714313001090	dimerization interface [polypeptide binding]; other site
714313001091	domain crossover interface; other site
714313001092	redox-dependent activation switch; other site
714313001093	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
714313001094	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
714313001095	FMN binding site [chemical binding]; other site
714313001096	active site
714313001097	catalytic residues [active]
714313001098	substrate binding site [chemical binding]; other site
714313001099	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
714313001100	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
714313001101	dimer interface [polypeptide binding]; other site
714313001102	putative anticodon binding site; other site
714313001103	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
714313001104	motif 1; other site
714313001105	active site
714313001106	motif 2; other site
714313001107	motif 3; other site
714313001108	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
714313001109	DNA binding residues [nucleotide binding]
714313001110	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
714313001111	putative dimer interface [polypeptide binding]; other site
714313001112	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
714313001113	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
714313001114	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
714313001115	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
714313001116	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313001117	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313001118	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
714313001119	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
714313001120	DNA-binding site [nucleotide binding]; DNA binding site
714313001121	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
714313001122	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
714313001123	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
714313001124	active site
714313001125	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
714313001126	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
714313001127	homodimer interface [polypeptide binding]; other site
714313001128	NAD binding pocket [chemical binding]; other site
714313001129	ATP binding pocket [chemical binding]; other site
714313001130	Mg binding site [ion binding]; other site
714313001131	active-site loop [active]
714313001132	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
714313001133	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
714313001134	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
714313001135	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
714313001136	RNA binding site [nucleotide binding]; other site
714313001137	hypothetical protein; Provisional; Region: PRK04351
714313001138	SprT homologues; Region: SprT; cl01182
714313001139	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
714313001140	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313001141	catalytic core [active]
714313001142	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313001143	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
714313001144	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
714313001145	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
714313001146	trimer interface [polypeptide binding]; other site
714313001147	active site
714313001148	G bulge; other site
714313001149	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
714313001150	tetramer (dimer of dimers) interface [polypeptide binding]; other site
714313001151	active site
714313001152	dimer interface [polypeptide binding]; other site
714313001153	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
714313001154	trimer interface [polypeptide binding]; other site
714313001155	active site
714313001156	DNA repair protein RadA; Provisional; Region: PRK11823
714313001157	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
714313001158	Walker A motif/ATP binding site; other site
714313001159	ATP binding site [chemical binding]; other site
714313001160	Walker B motif; other site
714313001161	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
714313001162	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
714313001163	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
714313001164	active site
714313001165	HIGH motif; other site
714313001166	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
714313001167	active site
714313001168	KMSKS motif; other site
714313001169	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
714313001170	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
714313001171	active site
714313001172	HIGH motif; other site
714313001173	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
714313001174	KMSKS motif; other site
714313001175	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
714313001176	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
714313001177	active site
714313001178	metal binding site [ion binding]; metal-binding site
714313001179	dimerization interface [polypeptide binding]; other site
714313001180	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
714313001181	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
714313001182	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
714313001183	YacP-like NYN domain; Region: NYN_YacP; pfam05991
714313001184	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
714313001185	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
714313001186	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
714313001187	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
714313001188	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
714313001189	putative homodimer interface [polypeptide binding]; other site
714313001190	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
714313001191	heterodimer interface [polypeptide binding]; other site
714313001192	homodimer interface [polypeptide binding]; other site
714313001193	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
714313001194	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
714313001195	23S rRNA interface [nucleotide binding]; other site
714313001196	L7/L12 interface [polypeptide binding]; other site
714313001197	putative thiostrepton binding site; other site
714313001198	L25 interface [polypeptide binding]; other site
714313001199	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
714313001200	mRNA/rRNA interface [nucleotide binding]; other site
714313001201	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
714313001202	23S rRNA interface [nucleotide binding]; other site
714313001203	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
714313001204	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
714313001205	peripheral dimer interface [polypeptide binding]; other site
714313001206	core dimer interface [polypeptide binding]; other site
714313001207	L10 interface [polypeptide binding]; other site
714313001208	L11 interface [polypeptide binding]; other site
714313001209	putative EF-Tu interaction site [polypeptide binding]; other site
714313001210	putative EF-G interaction site [polypeptide binding]; other site
714313001211	Predicted integral membrane protein [Function unknown]; Region: COG0392
714313001212	Uncharacterized conserved protein [Function unknown]; Region: COG2898
714313001213	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
714313001214	S-methylmethionine transporter; Provisional; Region: PRK11387
714313001215	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
714313001216	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
714313001217	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
714313001218	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
714313001219	tetramer (dimer of dimers) interface [polypeptide binding]; other site
714313001220	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
714313001221	NAD binding site [chemical binding]; other site
714313001222	dimer interface [polypeptide binding]; other site
714313001223	substrate binding site [chemical binding]; other site
714313001224	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
714313001225	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
714313001226	dimer interface [polypeptide binding]; other site
714313001227	putative radical transfer pathway; other site
714313001228	diiron center [ion binding]; other site
714313001229	tyrosyl radical; other site
714313001230	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07306
714313001231	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
714313001232	Class I ribonucleotide reductase; Region: RNR_I; cd01679
714313001233	active site
714313001234	dimer interface [polypeptide binding]; other site
714313001235	catalytic residues [active]
714313001236	effector binding site; other site
714313001237	R2 peptide binding site; other site
714313001238	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
714313001239	catalytic residues [active]
714313001240	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
714313001241	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313001242	S-adenosylmethionine binding site [chemical binding]; other site
714313001243	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
714313001244	nucleoside/Zn binding site; other site
714313001245	dimer interface [polypeptide binding]; other site
714313001246	catalytic motif [active]
714313001247	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
714313001248	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313001249	Walker A motif; other site
714313001250	ATP binding site [chemical binding]; other site
714313001251	Walker B motif; other site
714313001252	arginine finger; other site
714313001253	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
714313001254	hypothetical protein; Validated; Region: PRK00153
714313001255	recombination protein RecR; Reviewed; Region: recR; PRK00076
714313001256	RecR protein; Region: RecR; pfam02132
714313001257	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
714313001258	putative active site [active]
714313001259	putative metal-binding site [ion binding]; other site
714313001260	tetramer interface [polypeptide binding]; other site
714313001261	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
714313001262	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
714313001263	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
714313001264	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
714313001265	Walker A/P-loop; other site
714313001266	ATP binding site [chemical binding]; other site
714313001267	Q-loop/lid; other site
714313001268	ABC transporter signature motif; other site
714313001269	Walker B; other site
714313001270	D-loop; other site
714313001271	H-loop/switch region; other site
714313001272	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
714313001273	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
714313001274	FtsX-like permease family; Region: FtsX; pfam02687
714313001275	thymidylate kinase; Validated; Region: tmk; PRK00698
714313001276	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
714313001277	TMP-binding site; other site
714313001278	ATP-binding site [chemical binding]; other site
714313001279	Protein of unknown function (DUF970); Region: DUF970; cl17525
714313001280	DNA polymerase III subunit delta'; Validated; Region: PRK08058
714313001281	DNA polymerase III subunit delta'; Validated; Region: PRK08485
714313001282	Protein of unknown function (DUF972); Region: DUF972; pfam06156
714313001283	Predicted methyltransferases [General function prediction only]; Region: COG0313
714313001284	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
714313001285	putative SAM binding site [chemical binding]; other site
714313001286	putative homodimer interface [polypeptide binding]; other site
714313001287	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
714313001288	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
714313001289	active site
714313001290	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
714313001291	active site
714313001292	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
714313001293	Glycoprotease family; Region: Peptidase_M22; pfam00814
714313001294	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
714313001295	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
714313001296	Coenzyme A binding pocket [chemical binding]; other site
714313001297	UGMP family protein; Validated; Region: PRK09604
714313001298	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
714313001299	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
714313001300	dimerization interface [polypeptide binding]; other site
714313001301	putative DNA binding site [nucleotide binding]; other site
714313001302	putative Zn2+ binding site [ion binding]; other site
714313001303	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
714313001304	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
714313001305	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313001306	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313001307	ABC transporter; Region: ABC_tran_2; pfam12848
714313001308	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313001309	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
714313001310	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
714313001311	CoA binding domain; Region: CoA_binding; pfam02629
714313001312	Repair protein; Region: Repair_PSII; pfam04536
714313001313	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
714313001314	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
714313001315	oligomerisation interface [polypeptide binding]; other site
714313001316	mobile loop; other site
714313001317	roof hairpin; other site
714313001318	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
714313001319	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
714313001320	ring oligomerisation interface [polypeptide binding]; other site
714313001321	ATP/Mg binding site [chemical binding]; other site
714313001322	stacking interactions; other site
714313001323	hinge regions; other site
714313001324	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
714313001325	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
714313001326	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
714313001327	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313001328	Walker A/P-loop; other site
714313001329	ATP binding site [chemical binding]; other site
714313001330	Q-loop/lid; other site
714313001331	ABC transporter signature motif; other site
714313001332	Walker B; other site
714313001333	D-loop; other site
714313001334	H-loop/switch region; other site
714313001335	Uncharacterized conserved protein [Function unknown]; Region: COG1739
714313001336	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
714313001337	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
714313001338	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
714313001339	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313001340	active site
714313001341	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
714313001342	30S subunit binding site; other site
714313001343	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12906
714313001344	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
714313001345	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313001346	nucleotide binding region [chemical binding]; other site
714313001347	ATP-binding site [chemical binding]; other site
714313001348	peptide chain release factor 2; Validated; Region: prfB; PRK00578
714313001349	This domain is found in peptide chain release factors; Region: PCRF; smart00937
714313001350	RF-1 domain; Region: RF-1; pfam00472
714313001351	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
714313001352	Membrane protein of unknown function; Region: DUF360; cl00850
714313001353	HPr kinase/phosphorylase; Provisional; Region: PRK05428
714313001354	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
714313001355	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
714313001356	Hpr binding site; other site
714313001357	active site
714313001358	homohexamer subunit interaction site [polypeptide binding]; other site
714313001359	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
714313001360	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
714313001361	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
714313001362	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
714313001363	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
714313001364	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
714313001365	active site
714313001366	tetramer interface; other site
714313001367	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
714313001368	dimer interface [polypeptide binding]; other site
714313001369	catalytic triad [active]
714313001370	peroxidatic and resolving cysteines [active]
714313001371	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
714313001372	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
714313001373	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
714313001374	excinuclease ABC subunit B; Provisional; Region: PRK05298
714313001375	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
714313001376	ATP binding site [chemical binding]; other site
714313001377	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313001378	nucleotide binding region [chemical binding]; other site
714313001379	ATP-binding site [chemical binding]; other site
714313001380	Ultra-violet resistance protein B; Region: UvrB; pfam12344
714313001381	UvrB/uvrC motif; Region: UVR; pfam02151
714313001382	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
714313001383	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
714313001384	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
714313001385	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
714313001386	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
714313001387	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
714313001388	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
714313001389	phosphate binding site [ion binding]; other site
714313001390	putative substrate binding pocket [chemical binding]; other site
714313001391	dimer interface [polypeptide binding]; other site
714313001392	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
714313001393	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
714313001394	Clp protease; Region: CLP_protease; pfam00574
714313001395	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
714313001396	oligomer interface [polypeptide binding]; other site
714313001397	active site residues [active]
714313001398	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
714313001399	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
714313001400	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
714313001401	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
714313001402	Phosphoglycerate kinase; Region: PGK; pfam00162
714313001403	substrate binding site [chemical binding]; other site
714313001404	hinge regions; other site
714313001405	ADP binding site [chemical binding]; other site
714313001406	catalytic site [active]
714313001407	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
714313001408	triosephosphate isomerase; Provisional; Region: PRK14567
714313001409	substrate binding site [chemical binding]; other site
714313001410	dimer interface [polypeptide binding]; other site
714313001411	catalytic triad [active]
714313001412	enolase; Provisional; Region: eno; PRK00077
714313001413	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
714313001414	dimer interface [polypeptide binding]; other site
714313001415	metal binding site [ion binding]; metal-binding site
714313001416	substrate binding pocket [chemical binding]; other site
714313001417	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
714313001418	ribonuclease R; Region: RNase_R; TIGR02063
714313001419	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
714313001420	RNB domain; Region: RNB; pfam00773
714313001421	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
714313001422	RNA binding site [nucleotide binding]; other site
714313001423	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
714313001424	SmpB-tmRNA interface; other site
714313001425	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313001426	Homeodomain-like domain; Region: HTH_23; cl17451
714313001427	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313001428	HTH-like domain; Region: HTH_21; pfam13276
714313001429	Integrase core domain; Region: rve; pfam00665
714313001430	Integrase core domain; Region: rve_2; pfam13333
714313001431	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
714313001432	ligand binding site [chemical binding]; other site
714313001433	active site
714313001434	UGI interface [polypeptide binding]; other site
714313001435	catalytic site [active]
714313001436	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
714313001437	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
714313001438	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
714313001439	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
714313001440	Coenzyme A binding pocket [chemical binding]; other site
714313001441	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
714313001442	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
714313001443	active site
714313001444	catalytic site [active]
714313001445	substrate binding site [chemical binding]; other site
714313001446	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
714313001447	active site
714313001448	putative catalytic site [active]
714313001449	DNA binding site [nucleotide binding]
714313001450	putative phosphate binding site [ion binding]; other site
714313001451	metal binding site A [ion binding]; metal-binding site
714313001452	AP binding site [nucleotide binding]; other site
714313001453	metal binding site B [ion binding]; metal-binding site
714313001454	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
714313001455	FAD binding domain; Region: FAD_binding_4; pfam01565
714313001456	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
714313001457	Protein of unknown function (DUF1361); Region: DUF1361; pfam07099
714313001458	Uncharacterized conserved protein [Function unknown]; Region: COG1624
714313001459	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
714313001460	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
714313001461	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
714313001462	active site
714313001463	substrate binding site [chemical binding]; other site
714313001464	metal binding site [ion binding]; metal-binding site
714313001465	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
714313001466	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
714313001467	glutaminase active site [active]
714313001468	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
714313001469	dimer interface [polypeptide binding]; other site
714313001470	active site
714313001471	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
714313001472	dimer interface [polypeptide binding]; other site
714313001473	active site
714313001474	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
714313001475	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
714313001476	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
714313001477	putative dimer interface [polypeptide binding]; other site
714313001478	putative anticodon binding site; other site
714313001479	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
714313001480	homodimer interface [polypeptide binding]; other site
714313001481	motif 1; other site
714313001482	motif 2; other site
714313001483	active site
714313001484	motif 3; other site
714313001485	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313001486	Major Facilitator Superfamily; Region: MFS_1; pfam07690
714313001487	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313001488	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
714313001489	active site
714313001490	catalytic site [active]
714313001491	hypothetical protein; Provisional; Region: PRK04435
714313001492	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
714313001493	Protein of unknown function (DUF805); Region: DUF805; pfam05656
714313001494	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
714313001495	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
714313001496	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
714313001497	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
714313001498	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
714313001499	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
714313001500	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
714313001501	active site
714313001502	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
714313001503	Predicted membrane protein [Function unknown]; Region: COG4684
714313001504	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
714313001505	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
714313001506	Walker A/P-loop; other site
714313001507	ATP binding site [chemical binding]; other site
714313001508	Q-loop/lid; other site
714313001509	ABC transporter signature motif; other site
714313001510	Walker B; other site
714313001511	D-loop; other site
714313001512	H-loop/switch region; other site
714313001513	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
714313001514	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
714313001515	Walker A/P-loop; other site
714313001516	ATP binding site [chemical binding]; other site
714313001517	Q-loop/lid; other site
714313001518	ABC transporter signature motif; other site
714313001519	Walker B; other site
714313001520	D-loop; other site
714313001521	H-loop/switch region; other site
714313001522	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
714313001523	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
714313001524	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
714313001525	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
714313001526	Potassium binding sites [ion binding]; other site
714313001527	Cesium cation binding sites [ion binding]; other site
714313001528	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
714313001529	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
714313001530	tetramer interface [polypeptide binding]; other site
714313001531	active site
714313001532	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
714313001533	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
714313001534	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313001535	active site
714313001536	motif I; other site
714313001537	motif II; other site
714313001538	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
714313001539	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
714313001540	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
714313001541	putative RNA binding site [nucleotide binding]; other site
714313001542	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
714313001543	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
714313001544	nucleotide binding site [chemical binding]; other site
714313001545	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
714313001546	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
714313001547	active site
714313001548	dimer interface [polypeptide binding]; other site
714313001549	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
714313001550	dimer interface [polypeptide binding]; other site
714313001551	active site
714313001552	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
714313001553	active site
714313001554	catalytic site [active]
714313001555	recombination factor protein RarA; Reviewed; Region: PRK13342
714313001556	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313001557	Walker A motif; other site
714313001558	ATP binding site [chemical binding]; other site
714313001559	Walker B motif; other site
714313001560	arginine finger; other site
714313001561	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
714313001562	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
714313001563	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
714313001564	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
714313001565	active site
714313001566	FMN binding site [chemical binding]; other site
714313001567	substrate binding site [chemical binding]; other site
714313001568	catalytic residues [active]
714313001569	homodimer interface [polypeptide binding]; other site
714313001570	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
714313001571	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
714313001572	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
714313001573	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
714313001574	Predicted membrane protein [Function unknown]; Region: COG4325
714313001575	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
714313001576	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
714313001577	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
714313001578	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
714313001579	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
714313001580	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
714313001581	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
714313001582	active site
714313001583	HIGH motif; other site
714313001584	KMSK motif region; other site
714313001585	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
714313001586	tRNA binding surface [nucleotide binding]; other site
714313001587	anticodon binding site; other site
714313001588	Transglycosylase; Region: Transgly; pfam00912
714313001589	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
714313001590	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
714313001591	Protein of unknown function (DUF964); Region: DUF964; cl01483
714313001592	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
714313001593	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
714313001594	active site
714313001595	metal binding site [ion binding]; metal-binding site
714313001596	DNA binding site [nucleotide binding]
714313001597	AAA domain; Region: AAA_23; pfam13476
714313001598	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
714313001599	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
714313001600	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
714313001601	HIT family signature motif; other site
714313001602	catalytic residue [active]
714313001603	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
714313001604	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
714313001605	Walker A/P-loop; other site
714313001606	ATP binding site [chemical binding]; other site
714313001607	Q-loop/lid; other site
714313001608	ABC transporter signature motif; other site
714313001609	Walker B; other site
714313001610	D-loop; other site
714313001611	H-loop/switch region; other site
714313001612	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
714313001613	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313001614	S-adenosylmethionine binding site [chemical binding]; other site
714313001615	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
714313001616	catalytic residues [active]
714313001617	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
714313001618	putative tRNA-binding site [nucleotide binding]; other site
714313001619	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
714313001620	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
714313001621	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
714313001622	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
714313001623	DNA polymerase I; Provisional; Region: PRK05755
714313001624	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
714313001625	active site
714313001626	metal binding site 1 [ion binding]; metal-binding site
714313001627	putative 5' ssDNA interaction site; other site
714313001628	metal binding site 3; metal-binding site
714313001629	metal binding site 2 [ion binding]; metal-binding site
714313001630	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
714313001631	putative DNA binding site [nucleotide binding]; other site
714313001632	putative metal binding site [ion binding]; other site
714313001633	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
714313001634	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
714313001635	active site
714313001636	DNA binding site [nucleotide binding]
714313001637	catalytic site [active]
714313001638	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
714313001639	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
714313001640	DNA binding site [nucleotide binding]
714313001641	catalytic residue [active]
714313001642	H2TH interface [polypeptide binding]; other site
714313001643	putative catalytic residues [active]
714313001644	turnover-facilitating residue; other site
714313001645	intercalation triad [nucleotide binding]; other site
714313001646	8OG recognition residue [nucleotide binding]; other site
714313001647	putative reading head residues; other site
714313001648	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
714313001649	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
714313001650	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
714313001651	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
714313001652	CoA-binding site [chemical binding]; other site
714313001653	ATP-binding [chemical binding]; other site
714313001654	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
714313001655	ATP cone domain; Region: ATP-cone; pfam03477
714313001656	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
714313001657	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
714313001658	primosomal protein DnaI; Reviewed; Region: PRK08939
714313001659	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
714313001660	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
714313001661	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313001662	Walker A motif; other site
714313001663	ATP binding site [chemical binding]; other site
714313001664	Walker B motif; other site
714313001665	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
714313001666	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
714313001667	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
714313001668	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
714313001669	active site
714313001670	dimer interface [polypeptide binding]; other site
714313001671	motif 1; other site
714313001672	motif 2; other site
714313001673	motif 3; other site
714313001674	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
714313001675	anticodon binding site; other site
714313001676	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
714313001677	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
714313001678	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
714313001679	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
714313001680	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
714313001681	23S rRNA binding site [nucleotide binding]; other site
714313001682	L21 binding site [polypeptide binding]; other site
714313001683	L13 binding site [polypeptide binding]; other site
714313001684	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
714313001685	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
714313001686	GTPase YqeH; Provisional; Region: PRK13796
714313001687	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
714313001688	GTP/Mg2+ binding site [chemical binding]; other site
714313001689	G4 box; other site
714313001690	G5 box; other site
714313001691	G1 box; other site
714313001692	Switch I region; other site
714313001693	G2 box; other site
714313001694	G3 box; other site
714313001695	Switch II region; other site
714313001696	Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly; Region: CRS1_YhbY; smart01103
714313001697	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
714313001698	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
714313001699	active site
714313001700	(T/H)XGH motif; other site
714313001701	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
714313001702	Zn2+ binding site [ion binding]; other site
714313001703	Mg2+ binding site [ion binding]; other site
714313001704	Oligomerisation domain; Region: Oligomerisation; pfam02410
714313001705	Methyltransferase domain; Region: Methyltransf_23; pfam13489
714313001706	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313001707	S-adenosylmethionine binding site [chemical binding]; other site
714313001708	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
714313001709	hypothetical protein; Provisional; Region: PRK13670
714313001710	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
714313001711	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
714313001712	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
714313001713	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
714313001714	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
714313001715	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
714313001716	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
714313001717	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
714313001718	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
714313001719	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
714313001720	Predicted transcriptional regulators [Transcription]; Region: COG1733
714313001721	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
714313001722	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
714313001723	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
714313001724	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
714313001725	dimer interface [polypeptide binding]; other site
714313001726	motif 1; other site
714313001727	active site
714313001728	motif 2; other site
714313001729	motif 3; other site
714313001730	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
714313001731	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
714313001732	putative tRNA-binding site [nucleotide binding]; other site
714313001733	B3/4 domain; Region: B3_4; pfam03483
714313001734	tRNA synthetase B5 domain; Region: B5; smart00874
714313001735	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
714313001736	dimer interface [polypeptide binding]; other site
714313001737	motif 1; other site
714313001738	motif 3; other site
714313001739	motif 2; other site
714313001740	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
714313001741	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
714313001742	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
714313001743	Sugar specificity; other site
714313001744	Pyrimidine base specificity; other site
714313001745	ATP-binding site [chemical binding]; other site
714313001746	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
714313001747	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
714313001748	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
714313001749	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
714313001750	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
714313001751	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
714313001752	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
714313001753	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
714313001754	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
714313001755	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
714313001756	Rhomboid family; Region: Rhomboid; pfam01694
714313001757	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
714313001758	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
714313001759	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
714313001760	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
714313001761	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
714313001762	active site residue [active]
714313001763	Protein of unknown function (DUF3042); Region: DUF3042; pfam11240
714313001764	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
714313001765	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
714313001766	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
714313001767	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
714313001768	Protein of unknown function (DUF464); Region: DUF464; pfam04327
714313001769	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
714313001770	elongation factor P; Validated; Region: PRK00529
714313001771	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
714313001772	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
714313001773	RNA binding site [nucleotide binding]; other site
714313001774	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
714313001775	RNA binding site [nucleotide binding]; other site
714313001776	Asp23 family; Region: Asp23; pfam03780
714313001777	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
714313001778	putative RNA binding site [nucleotide binding]; other site
714313001779	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
714313001780	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
714313001781	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
714313001782	homodimer interface [polypeptide binding]; other site
714313001783	NADP binding site [chemical binding]; other site
714313001784	substrate binding site [chemical binding]; other site
714313001785	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
714313001786	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
714313001787	generic binding surface II; other site
714313001788	generic binding surface I; other site
714313001789	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
714313001790	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
714313001791	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
714313001792	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
714313001793	substrate binding pocket [chemical binding]; other site
714313001794	chain length determination region; other site
714313001795	substrate-Mg2+ binding site; other site
714313001796	catalytic residues [active]
714313001797	aspartate-rich region 1; other site
714313001798	active site lid residues [active]
714313001799	aspartate-rich region 2; other site
714313001800	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
714313001801	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
714313001802	RNA binding surface [nucleotide binding]; other site
714313001803	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
714313001804	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
714313001805	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
714313001806	Walker A/P-loop; other site
714313001807	ATP binding site [chemical binding]; other site
714313001808	Q-loop/lid; other site
714313001809	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
714313001810	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
714313001811	ABC transporter signature motif; other site
714313001812	Walker B; other site
714313001813	D-loop; other site
714313001814	H-loop/switch region; other site
714313001815	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
714313001816	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
714313001817	catalytic site [active]
714313001818	G-X2-G-X-G-K; other site
714313001819	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
714313001820	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
714313001821	Flavoprotein; Region: Flavoprotein; pfam02441
714313001822	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
714313001823	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
714313001824	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
714313001825	ATP binding site [chemical binding]; other site
714313001826	putative Mg++ binding site [ion binding]; other site
714313001827	helicase superfamily c-terminal domain; Region: HELICc; smart00490
714313001828	nucleotide binding region [chemical binding]; other site
714313001829	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
714313001830	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
714313001831	putative active site [active]
714313001832	substrate binding site [chemical binding]; other site
714313001833	putative cosubstrate binding site; other site
714313001834	catalytic site [active]
714313001835	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
714313001836	substrate binding site [chemical binding]; other site
714313001837	16S rRNA methyltransferase B; Provisional; Region: PRK14902
714313001838	NusB family; Region: NusB; pfam01029
714313001839	putative RNA binding site [nucleotide binding]; other site
714313001840	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313001841	S-adenosylmethionine binding site [chemical binding]; other site
714313001842	GTPase RsgA; Reviewed; Region: PRK00098
714313001843	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
714313001844	RNA binding site [nucleotide binding]; other site
714313001845	homodimer interface [polypeptide binding]; other site
714313001846	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
714313001847	GTPase/Zn-binding domain interface [polypeptide binding]; other site
714313001848	GTP/Mg2+ binding site [chemical binding]; other site
714313001849	G4 box; other site
714313001850	G5 box; other site
714313001851	G1 box; other site
714313001852	Switch I region; other site
714313001853	G2 box; other site
714313001854	G3 box; other site
714313001855	Switch II region; other site
714313001856	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
714313001857	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
714313001858	substrate binding site [chemical binding]; other site
714313001859	hexamer interface [polypeptide binding]; other site
714313001860	metal binding site [ion binding]; metal-binding site
714313001861	Thiamine pyrophosphokinase; Region: TPK; cd07995
714313001862	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
714313001863	active site
714313001864	dimerization interface [polypeptide binding]; other site
714313001865	thiamine binding site [chemical binding]; other site
714313001866	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
714313001867	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
714313001868	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
714313001869	DAK2 domain; Region: Dak2; pfam02734
714313001870	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
714313001871	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
714313001872	generic binding surface II; other site
714313001873	ssDNA binding site; other site
714313001874	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
714313001875	ATP binding site [chemical binding]; other site
714313001876	putative Mg++ binding site [ion binding]; other site
714313001877	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313001878	nucleotide binding region [chemical binding]; other site
714313001879	ATP-binding site [chemical binding]; other site
714313001880	putative phosphate acyltransferase; Provisional; Region: PRK05331
714313001881	ribonuclease III; Reviewed; Region: rnc; PRK00102
714313001882	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
714313001883	dimerization interface [polypeptide binding]; other site
714313001884	active site
714313001885	metal binding site [ion binding]; metal-binding site
714313001886	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
714313001887	dsRNA binding site [nucleotide binding]; other site
714313001888	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
714313001889	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
714313001890	Walker A/P-loop; other site
714313001891	ATP binding site [chemical binding]; other site
714313001892	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
714313001893	variable surface protein Vir23; Provisional; Region: PTZ00250
714313001894	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
714313001895	ABC transporter signature motif; other site
714313001896	Walker B; other site
714313001897	D-loop; other site
714313001898	H-loop/switch region; other site
714313001899	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
714313001900	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
714313001901	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
714313001902	P loop; other site
714313001903	GTP binding site [chemical binding]; other site
714313001904	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
714313001905	putative DNA-binding protein; Validated; Region: PRK00118
714313001906	signal recognition particle protein; Provisional; Region: PRK10867
714313001907	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
714313001908	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
714313001909	P loop; other site
714313001910	GTP binding site [chemical binding]; other site
714313001911	Signal peptide binding domain; Region: SRP_SPB; pfam02978
714313001912	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
714313001913	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
714313001914	KH domain; Region: KH_4; pfam13083
714313001915	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
714313001916	RimM N-terminal domain; Region: RimM; pfam01782
714313001917	PRC-barrel domain; Region: PRC; pfam05239
714313001918	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
714313001919	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
714313001920	inner membrane transporter YjeM; Provisional; Region: PRK15238
714313001921	Peptidase family C69; Region: Peptidase_C69; pfam03577
714313001922	glycerol kinase; Provisional; Region: glpK; PRK00047
714313001923	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
714313001924	N- and C-terminal domain interface [polypeptide binding]; other site
714313001925	active site
714313001926	MgATP binding site [chemical binding]; other site
714313001927	catalytic site [active]
714313001928	metal binding site [ion binding]; metal-binding site
714313001929	glycerol binding site [chemical binding]; other site
714313001930	homotetramer interface [polypeptide binding]; other site
714313001931	homodimer interface [polypeptide binding]; other site
714313001932	FBP binding site [chemical binding]; other site
714313001933	protein IIAGlc interface [polypeptide binding]; other site
714313001934	Methyltransferase domain; Region: Methyltransf_31; pfam13847
714313001935	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313001936	S-adenosylmethionine binding site [chemical binding]; other site
714313001937	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
714313001938	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
714313001939	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
714313001940	homotetramer interface [polypeptide binding]; other site
714313001941	FMN binding site [chemical binding]; other site
714313001942	homodimer contacts [polypeptide binding]; other site
714313001943	putative active site [active]
714313001944	putative substrate binding site [chemical binding]; other site
714313001945	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
714313001946	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
714313001947	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
714313001948	diphosphomevalonate decarboxylase; Region: PLN02407
714313001949	mevalonate kinase; Region: mevalon_kin; TIGR00549
714313001950	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
714313001951	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
714313001952	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
714313001953	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
714313001954	active site
714313001955	catalytic site [active]
714313001956	substrate binding site [chemical binding]; other site
714313001957	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
714313001958	ATP binding site [chemical binding]; other site
714313001959	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
714313001960	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
714313001961	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
714313001962	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
714313001963	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
714313001964	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
714313001965	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
714313001966	substrate binding pocket [chemical binding]; other site
714313001967	chain length determination region; other site
714313001968	substrate-Mg2+ binding site; other site
714313001969	catalytic residues [active]
714313001970	aspartate-rich region 1; other site
714313001971	active site lid residues [active]
714313001972	aspartate-rich region 2; other site
714313001973	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
714313001974	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
714313001975	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313001976	Walker A/P-loop; other site
714313001977	ATP binding site [chemical binding]; other site
714313001978	Q-loop/lid; other site
714313001979	ABC transporter signature motif; other site
714313001980	Walker B; other site
714313001981	D-loop; other site
714313001982	H-loop/switch region; other site
714313001983	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
714313001984	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
714313001985	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313001986	Walker A/P-loop; other site
714313001987	ATP binding site [chemical binding]; other site
714313001988	Q-loop/lid; other site
714313001989	ABC transporter signature motif; other site
714313001990	Walker B; other site
714313001991	D-loop; other site
714313001992	H-loop/switch region; other site
714313001993	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
714313001994	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
714313001995	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
714313001996	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
714313001997	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
714313001998	Winged helix-turn helix; Region: HTH_29; pfam13551
714313001999	HTH-like domain; Region: HTH_21; pfam13276
714313002000	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
714313002001	Integrase core domain; Region: rve; pfam00665
714313002002	Integrase core domain; Region: rve_3; cl15866
714313002003	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
714313002004	UbiA prenyltransferase family; Region: UbiA; pfam01040
714313002005	Transglycosylase; Region: Transgly; pfam00912
714313002006	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
714313002007	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
714313002008	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
714313002009	hypothetical protein; Provisional; Region: PRK13660
714313002010	cell division protein GpsB; Provisional; Region: PRK14127
714313002011	DivIVA domain; Region: DivI1A_domain; TIGR03544
714313002012	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
714313002013	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
714313002014	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
714313002015	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
714313002016	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
714313002017	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
714313002018	RNA/DNA hybrid binding site [nucleotide binding]; other site
714313002019	active site
714313002020	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
714313002021	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
714313002022	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
714313002023	RNA binding surface [nucleotide binding]; other site
714313002024	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
714313002025	active site
714313002026	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
714313002027	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313002028	active site
714313002029	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12838
714313002030	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
714313002031	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
714313002032	conserved cys residue [active]
714313002033	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
714313002034	ATP-grasp domain; Region: ATP-grasp_4; cl17255
714313002035	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
714313002036	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
714313002037	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
714313002038	Domain of unknown function (DUF814); Region: DUF814; pfam05670
714313002039	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
714313002040	MarR family; Region: MarR_2; pfam12802
714313002041	EDD domain protein, DegV family; Region: DegV; TIGR00762
714313002042	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
714313002043	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
714313002044	methionine sulfoxide reductase A; Provisional; Region: PRK14054
714313002045	methionine sulfoxide reductase B; Provisional; Region: PRK00222
714313002046	SelR domain; Region: SelR; pfam01641
714313002047	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
714313002048	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
714313002049	DHHA2 domain; Region: DHHA2; pfam02833
714313002050	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
714313002051	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
714313002052	CAP-like domain; other site
714313002053	active site
714313002054	primary dimer interface [polypeptide binding]; other site
714313002055	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
714313002056	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
714313002057	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
714313002058	Mg2+ binding site [ion binding]; other site
714313002059	G-X-G motif; other site
714313002060	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
714313002061	anchoring element; other site
714313002062	dimer interface [polypeptide binding]; other site
714313002063	ATP binding site [chemical binding]; other site
714313002064	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
714313002065	active site
714313002066	putative metal-binding site [ion binding]; other site
714313002067	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
714313002068	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
714313002069	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
714313002070	active site
714313002071	catalytic residues [active]
714313002072	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
714313002073	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
714313002074	active site
714313002075	DNA binding site [nucleotide binding]
714313002076	Int/Topo IB signature motif; other site
714313002077	DNA topoisomerase I; Validated; Region: PRK05582
714313002078	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
714313002079	active site
714313002080	interdomain interaction site; other site
714313002081	putative metal-binding site [ion binding]; other site
714313002082	nucleotide binding site [chemical binding]; other site
714313002083	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
714313002084	domain I; other site
714313002085	DNA binding groove [nucleotide binding]
714313002086	phosphate binding site [ion binding]; other site
714313002087	domain II; other site
714313002088	domain III; other site
714313002089	nucleotide binding site [chemical binding]; other site
714313002090	catalytic site [active]
714313002091	domain IV; other site
714313002092	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
714313002093	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
714313002094	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
714313002095	RNA/DNA hybrid binding site [nucleotide binding]; other site
714313002096	active site
714313002097	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
714313002098	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
714313002099	GTP/Mg2+ binding site [chemical binding]; other site
714313002100	G4 box; other site
714313002101	G5 box; other site
714313002102	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
714313002103	G1 box; other site
714313002104	G1 box; other site
714313002105	GTP/Mg2+ binding site [chemical binding]; other site
714313002106	Switch I region; other site
714313002107	G2 box; other site
714313002108	G2 box; other site
714313002109	Switch I region; other site
714313002110	G3 box; other site
714313002111	G3 box; other site
714313002112	Switch II region; other site
714313002113	Switch II region; other site
714313002114	hypothetical protein; Provisional; Region: PRK13672
714313002115	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
714313002116	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
714313002117	folate binding site [chemical binding]; other site
714313002118	NADP+ binding site [chemical binding]; other site
714313002119	thymidylate synthase; Region: thym_sym; TIGR03284
714313002120	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
714313002121	dimerization interface [polypeptide binding]; other site
714313002122	active site
714313002123	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
714313002124	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313002125	Walker A/P-loop; other site
714313002126	ATP binding site [chemical binding]; other site
714313002127	Q-loop/lid; other site
714313002128	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313002129	ABC transporter signature motif; other site
714313002130	Walker B; other site
714313002131	D-loop; other site
714313002132	ABC transporter; Region: ABC_tran_2; pfam12848
714313002133	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
714313002134	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
714313002135	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
714313002136	active site
714313002137	NTP binding site [chemical binding]; other site
714313002138	metal binding triad [ion binding]; metal-binding site
714313002139	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
714313002140	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
714313002141	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
714313002142	binding surface
714313002143	TPR motif; other site
714313002144	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
714313002145	TPR motif; other site
714313002146	Tetratricopeptide repeat; Region: TPR_16; pfam13432
714313002147	binding surface
714313002148	Tetratricopeptide repeat; Region: TPR_12; pfam13424
714313002149	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
714313002150	binding surface
714313002151	TPR motif; other site
714313002152	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
714313002153	binding surface
714313002154	TPR motif; other site
714313002155	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
714313002156	IHF dimer interface [polypeptide binding]; other site
714313002157	IHF - DNA interface [nucleotide binding]; other site
714313002158	GTP-binding protein Der; Reviewed; Region: PRK00093
714313002159	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
714313002160	G1 box; other site
714313002161	GTP/Mg2+ binding site [chemical binding]; other site
714313002162	Switch I region; other site
714313002163	G2 box; other site
714313002164	Switch II region; other site
714313002165	G3 box; other site
714313002166	G4 box; other site
714313002167	G5 box; other site
714313002168	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
714313002169	G1 box; other site
714313002170	GTP/Mg2+ binding site [chemical binding]; other site
714313002171	Switch I region; other site
714313002172	G2 box; other site
714313002173	G3 box; other site
714313002174	Switch II region; other site
714313002175	G4 box; other site
714313002176	G5 box; other site
714313002177	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
714313002178	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
714313002179	RNA binding site [nucleotide binding]; other site
714313002180	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
714313002181	RNA binding site [nucleotide binding]; other site
714313002182	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
714313002183	RNA binding site [nucleotide binding]; other site
714313002184	cytidylate kinase; Provisional; Region: cmk; PRK00023
714313002185	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
714313002186	CMP-binding site; other site
714313002187	The sites determining sugar specificity; other site
714313002188	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
714313002189	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
714313002190	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
714313002191	ATP binding site [chemical binding]; other site
714313002192	putative Mg++ binding site [ion binding]; other site
714313002193	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313002194	nucleotide binding region [chemical binding]; other site
714313002195	ATP-binding site [chemical binding]; other site
714313002196	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
714313002197	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
714313002198	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
714313002199	RNA binding surface [nucleotide binding]; other site
714313002200	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
714313002201	active site
714313002202	Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612
714313002203	ScpA/B protein; Region: ScpA_ScpB; cl00598
714313002204	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
714313002205	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
714313002206	active site
714313002207	Int/Topo IB signature motif; other site
714313002208	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
714313002209	S1 domain; Region: S1_2; pfam13509
714313002210	pyruvate kinase; Provisional; Region: PRK06354
714313002211	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
714313002212	domain interfaces; other site
714313002213	active site
714313002214	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
714313002215	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
714313002216	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
714313002217	active site
714313002218	PHP Thumb interface [polypeptide binding]; other site
714313002219	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
714313002220	generic binding surface I; other site
714313002221	generic binding surface II; other site
714313002222	Uncharacterized conserved protein [Function unknown]; Region: COG0327
714313002223	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
714313002224	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
714313002225	Family of unknown function (DUF633); Region: DUF633; pfam04816
714313002226	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
714313002227	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
714313002228	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
714313002229	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
714313002230	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
714313002231	DNA binding residues [nucleotide binding]
714313002232	DNA primase; Validated; Region: dnaG; PRK05667
714313002233	CHC2 zinc finger; Region: zf-CHC2; pfam01807
714313002234	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
714313002235	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
714313002236	active site
714313002237	metal binding site [ion binding]; metal-binding site
714313002238	interdomain interaction site; other site
714313002239	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
714313002240	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
714313002241	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
714313002242	dimer interface [polypeptide binding]; other site
714313002243	motif 1; other site
714313002244	active site
714313002245	motif 2; other site
714313002246	motif 3; other site
714313002247	Recombination protein O N terminal; Region: RecO_N; pfam11967
714313002248	DNA repair protein RecO; Region: reco; TIGR00613
714313002249	Recombination protein O C terminal; Region: RecO_C; pfam02565
714313002250	GTPase Era; Reviewed; Region: era; PRK00089
714313002251	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
714313002252	G1 box; other site
714313002253	GTP/Mg2+ binding site [chemical binding]; other site
714313002254	Switch I region; other site
714313002255	G2 box; other site
714313002256	Switch II region; other site
714313002257	G3 box; other site
714313002258	G4 box; other site
714313002259	G5 box; other site
714313002260	KH domain; Region: KH_2; pfam07650
714313002261	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
714313002262	metal-binding heat shock protein; Provisional; Region: PRK00016
714313002263	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
714313002264	PhoH-like protein; Region: PhoH; pfam02562
714313002265	Yqey-like protein; Region: YqeY; pfam09424
714313002266	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
714313002267	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
714313002268	endonuclease IV; Provisional; Region: PRK01060
714313002269	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
714313002270	AP (apurinic/apyrimidinic) site pocket; other site
714313002271	DNA interaction; other site
714313002272	Metal-binding active site; metal-binding site
714313002273	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
714313002274	Uncharacterized conserved protein [Function unknown]; Region: COG1284
714313002275	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
714313002276	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
714313002277	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
714313002278	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
714313002279	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
714313002280	dimer interface [polypeptide binding]; other site
714313002281	anticodon binding site; other site
714313002282	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
714313002283	homodimer interface [polypeptide binding]; other site
714313002284	motif 1; other site
714313002285	active site
714313002286	motif 2; other site
714313002287	GAD domain; Region: GAD; pfam02938
714313002288	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
714313002289	active site
714313002290	motif 3; other site
714313002291	Bacterial SH3 domain; Region: SH3_3; pfam08239
714313002292	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
714313002293	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
714313002294	active site
714313002295	metal binding site [ion binding]; metal-binding site
714313002296	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
714313002297	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313002298	motif II; other site
714313002299	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
714313002300	putative active site [active]
714313002301	dimerization interface [polypeptide binding]; other site
714313002302	putative tRNAtyr binding site [nucleotide binding]; other site
714313002303	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
714313002304	HD domain; Region: HD_4; pfam13328
714313002305	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
714313002306	synthetase active site [active]
714313002307	NTP binding site [chemical binding]; other site
714313002308	metal binding site [ion binding]; metal-binding site
714313002309	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
714313002310	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
714313002311	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
714313002312	RNA methyltransferase, RsmE family; Region: TIGR00046
714313002313	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
714313002314	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313002315	S-adenosylmethionine binding site [chemical binding]; other site
714313002316	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
714313002317	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
714313002318	active site
714313002319	metal binding site [ion binding]; metal-binding site
714313002320	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
714313002321	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
714313002322	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
714313002323	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
714313002324	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
714313002325	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
714313002326	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
714313002327	GTP-binding protein LepA; Provisional; Region: PRK05433
714313002328	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
714313002329	G1 box; other site
714313002330	putative GEF interaction site [polypeptide binding]; other site
714313002331	GTP/Mg2+ binding site [chemical binding]; other site
714313002332	Switch I region; other site
714313002333	G2 box; other site
714313002334	G3 box; other site
714313002335	Switch II region; other site
714313002336	G4 box; other site
714313002337	G5 box; other site
714313002338	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
714313002339	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
714313002340	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
714313002341	chaperone protein DnaJ; Provisional; Region: PRK14276
714313002342	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
714313002343	HSP70 interaction site [polypeptide binding]; other site
714313002344	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
714313002345	substrate binding site [polypeptide binding]; other site
714313002346	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
714313002347	Zn binding sites [ion binding]; other site
714313002348	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
714313002349	dimer interface [polypeptide binding]; other site
714313002350	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
714313002351	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
714313002352	nucleotide binding site [chemical binding]; other site
714313002353	NEF interaction site [polypeptide binding]; other site
714313002354	SBD interface [polypeptide binding]; other site
714313002355	GrpE; Region: GrpE; pfam01025
714313002356	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
714313002357	dimer interface [polypeptide binding]; other site
714313002358	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
714313002359	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
714313002360	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
714313002361	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
714313002362	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
714313002363	active site
714313002364	Riboflavin kinase; Region: Flavokinase; smart00904
714313002365	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01550
714313002366	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
714313002367	RNA binding site [nucleotide binding]; other site
714313002368	active site
714313002369	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
714313002370	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
714313002371	translation initiation factor IF-2; Region: IF-2; TIGR00487
714313002372	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
714313002373	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
714313002374	G1 box; other site
714313002375	putative GEF interaction site [polypeptide binding]; other site
714313002376	GTP/Mg2+ binding site [chemical binding]; other site
714313002377	Switch I region; other site
714313002378	G2 box; other site
714313002379	G3 box; other site
714313002380	Switch II region; other site
714313002381	G4 box; other site
714313002382	G5 box; other site
714313002383	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
714313002384	Translation-initiation factor 2; Region: IF-2; pfam11987
714313002385	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
714313002386	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
714313002387	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
714313002388	putative RNA binding cleft [nucleotide binding]; other site
714313002389	Sm and related proteins; Region: Sm_like; cl00259
714313002390	ribosome maturation protein RimP; Reviewed; Region: PRK00092
714313002391	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
714313002392	putative oligomer interface [polypeptide binding]; other site
714313002393	putative RNA binding site [nucleotide binding]; other site
714313002394	DNA polymerase III PolC; Validated; Region: polC; PRK00448
714313002395	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
714313002396	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
714313002397	generic binding surface II; other site
714313002398	generic binding surface I; other site
714313002399	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
714313002400	active site
714313002401	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
714313002402	active site
714313002403	catalytic site [active]
714313002404	substrate binding site [chemical binding]; other site
714313002405	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
714313002406	prolyl-tRNA synthetase; Provisional; Region: PRK09194
714313002407	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
714313002408	motif 1; other site
714313002409	dimer interface [polypeptide binding]; other site
714313002410	active site
714313002411	motif 2; other site
714313002412	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
714313002413	putative deacylase active site [active]
714313002414	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
714313002415	active site
714313002416	motif 3; other site
714313002417	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
714313002418	anticodon binding site; other site
714313002419	RIP metalloprotease RseP; Region: TIGR00054
714313002420	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
714313002421	active site
714313002422	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
714313002423	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
714313002424	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
714313002425	putative substrate binding region [chemical binding]; other site
714313002426	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
714313002427	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
714313002428	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14830
714313002429	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
714313002430	catalytic residue [active]
714313002431	putative FPP diphosphate  binding site; other site
714313002432	putative FPP binding hydrophobic cleft; other site
714313002433	dimer interface [polypeptide binding]; other site
714313002434	putative IPP diphosphate binding site; other site
714313002435	ribosome recycling factor; Reviewed; Region: frr; PRK00083
714313002436	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
714313002437	hinge region; other site
714313002438	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
714313002439	putative nucleotide binding site [chemical binding]; other site
714313002440	uridine monophosphate binding site [chemical binding]; other site
714313002441	homohexameric interface [polypeptide binding]; other site
714313002442	elongation factor Ts; Provisional; Region: tsf; PRK09377
714313002443	UBA/TS-N domain; Region: UBA; pfam00627
714313002444	Elongation factor TS; Region: EF_TS; pfam00889
714313002445	Elongation factor TS; Region: EF_TS; pfam00889
714313002446	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
714313002447	rRNA interaction site [nucleotide binding]; other site
714313002448	S8 interaction site; other site
714313002449	putative laminin-1 binding site; other site
714313002450	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
714313002451	GIY-YIG motif/motif A; other site
714313002452	putative active site [active]
714313002453	putative metal binding site [ion binding]; other site
714313002454	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
714313002455	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313002456	S-adenosylmethionine binding site [chemical binding]; other site
714313002457	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
714313002458	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
714313002459	putative acyl-acceptor binding pocket; other site
714313002460	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
714313002461	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
714313002462	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
714313002463	putative DNA binding site [nucleotide binding]; other site
714313002464	LexA repressor; Validated; Region: PRK00215
714313002465	putative Zn2+ binding site [ion binding]; other site
714313002466	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
714313002467	Catalytic site [active]
714313002468	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
714313002469	tetramer interfaces [polypeptide binding]; other site
714313002470	binuclear metal-binding site [ion binding]; other site
714313002471	CAAX protease self-immunity; Region: Abi; pfam02517
714313002472	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
714313002473	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
714313002474	Substrate-binding site [chemical binding]; other site
714313002475	Substrate specificity [chemical binding]; other site
714313002476	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
714313002477	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
714313002478	metal binding site [ion binding]; metal-binding site
714313002479	dimer interface [polypeptide binding]; other site
714313002480	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
714313002481	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
714313002482	dipeptidase PepV; Reviewed; Region: PRK07318
714313002483	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
714313002484	active site
714313002485	metal binding site [ion binding]; metal-binding site
714313002486	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
714313002487	putative substrate binding site [chemical binding]; other site
714313002488	putative ATP binding site [chemical binding]; other site
714313002489	stage V sporulation protein B; Region: spore_V_B; TIGR02900
714313002490	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
714313002491	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
714313002492	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
714313002493	HIGH motif; other site
714313002494	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
714313002495	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
714313002496	active site
714313002497	KMSKS motif; other site
714313002498	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
714313002499	tRNA binding surface [nucleotide binding]; other site
714313002500	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
714313002501	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
714313002502	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313002503	Major Facilitator Superfamily; Region: MFS_1; pfam07690
714313002504	putative substrate translocation pore; other site
714313002505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313002506	S-adenosylmethionine synthetase; Validated; Region: PRK05250
714313002507	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
714313002508	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
714313002509	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
714313002510	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
714313002511	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313002512	Walker A/P-loop; other site
714313002513	ATP binding site [chemical binding]; other site
714313002514	Q-loop/lid; other site
714313002515	ABC transporter signature motif; other site
714313002516	Walker B; other site
714313002517	D-loop; other site
714313002518	H-loop/switch region; other site
714313002519	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313002520	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
714313002521	dimer interface [polypeptide binding]; other site
714313002522	conserved gate region; other site
714313002523	putative PBP binding loops; other site
714313002524	ABC-ATPase subunit interface; other site
714313002525	uracil transporter; Provisional; Region: PRK10720
714313002526	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
714313002527	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
714313002528	dimer interface [polypeptide binding]; other site
714313002529	active site
714313002530	aromatic amino acid aminotransferase; Validated; Region: PRK07309
714313002531	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
714313002532	pyridoxal 5'-phosphate binding site [chemical binding]; other site
714313002533	homodimer interface [polypeptide binding]; other site
714313002534	catalytic residue [active]
714313002535	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
714313002536	CRISPR/Cas system-associated protein Csn2; Region: Csn2; cd12218
714313002537	CRISPR type II-A/NMEMI-associated protein Csn2; Region: cas_Csn2; TIGR01866
714313002538	tetramer interface [polypeptide binding]; other site
714313002539	putative DNA binding site [nucleotide binding]; other site
714313002540	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09638
714313002541	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
714313002542	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
714313002543	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
714313002544	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
714313002545	Beta-lactamase; Region: Beta-lactamase; pfam00144
714313002546	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
714313002547	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
714313002548	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
714313002549	Protein of unknown function (DUF1461); Region: DUF1461; cl01862
714313002550	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
714313002551	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313002552	active site
714313002553	motif I; other site
714313002554	motif II; other site
714313002555	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
714313002556	Protein of unknown function (DUF1027); Region: DUF1027; cl09961
714313002557	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
714313002558	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
714313002559	active site
714313002560	metal binding site [ion binding]; metal-binding site
714313002561	Phosphotransferase enzyme family; Region: APH; pfam01636
714313002562	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
714313002563	active site
714313002564	ATP binding site [chemical binding]; other site
714313002565	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
714313002566	substrate binding site [chemical binding]; other site
714313002567	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
714313002568	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
714313002569	propionate/acetate kinase; Provisional; Region: PRK12379
714313002570	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
714313002571	Methyltransferase domain; Region: Methyltransf_26; pfam13659
714313002572	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
714313002573	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
714313002574	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
714313002575	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
714313002576	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
714313002577	Type II/IV secretion system protein; Region: T2SE; pfam00437
714313002578	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
714313002579	Walker A motif; other site
714313002580	ATP binding site [chemical binding]; other site
714313002581	Walker B motif; other site
714313002582	hypothetical protein; Validated; Region: PRK00110
714313002583	catabolite control protein A; Region: ccpA; TIGR01481
714313002584	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
714313002585	DNA binding site [nucleotide binding]
714313002586	domain linker motif; other site
714313002587	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
714313002588	dimerization interface [polypeptide binding]; other site
714313002589	effector binding site; other site
714313002590	Bacterial protein of unknown function (DUF948); Region: DUF948; cl01972
714313002591	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
714313002592	Mechanosensitive ion channel; Region: MS_channel; pfam00924
714313002593	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
714313002594	active site
714313002595	dimerization interface [polypeptide binding]; other site
714313002596	glutamate racemase; Provisional; Region: PRK00865
714313002597	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
714313002598	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
714313002599	catalytic residues [active]
714313002600	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
714313002601	MutS domain III; Region: MutS_III; pfam05192
714313002602	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
714313002603	Walker A/P-loop; other site
714313002604	ATP binding site [chemical binding]; other site
714313002605	Q-loop/lid; other site
714313002606	ABC transporter signature motif; other site
714313002607	Walker B; other site
714313002608	D-loop; other site
714313002609	H-loop/switch region; other site
714313002610	Smr domain; Region: Smr; pfam01713
714313002611	Colicin V production protein; Region: Colicin_V; pfam02674
714313002612	Cell division protein ZapA; Region: ZapA; pfam05164
714313002613	hypothetical protein; Provisional; Region: PRK13678
714313002614	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
714313002615	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
714313002616	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
714313002617	motif 1; other site
714313002618	active site
714313002619	motif 2; other site
714313002620	motif 3; other site
714313002621	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
714313002622	DHHA1 domain; Region: DHHA1; pfam02272
714313002623	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
714313002624	DEAD-like helicases superfamily; Region: DEXDc; smart00487
714313002625	ATP binding site [chemical binding]; other site
714313002626	Mg++ binding site [ion binding]; other site
714313002627	motif III; other site
714313002628	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313002629	nucleotide binding region [chemical binding]; other site
714313002630	ATP-binding site [chemical binding]; other site
714313002631	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
714313002632	DHH family; Region: DHH; pfam01368
714313002633	DHHA1 domain; Region: DHHA1; pfam02272
714313002634	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
714313002635	active site
714313002636	DNA polymerase IV; Validated; Region: PRK02406
714313002637	DNA binding site [nucleotide binding]
714313002638	Preprotein translocase subunit; Region: YajC; pfam02699
714313002639	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
714313002640	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313002641	Walker A motif; other site
714313002642	ATP binding site [chemical binding]; other site
714313002643	Walker B motif; other site
714313002644	arginine finger; other site
714313002645	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
714313002646	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
714313002647	RuvA N terminal domain; Region: RuvA_N; pfam01330
714313002648	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
714313002649	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
714313002650	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
714313002651	ATP binding site [chemical binding]; other site
714313002652	Mg2+ binding site [ion binding]; other site
714313002653	G-X-G motif; other site
714313002654	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
714313002655	ATP binding site [chemical binding]; other site
714313002656	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
714313002657	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
714313002658	MutS domain I; Region: MutS_I; pfam01624
714313002659	MutS domain II; Region: MutS_II; pfam05188
714313002660	MutS domain III; Region: MutS_III; pfam05192
714313002661	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
714313002662	Walker A/P-loop; other site
714313002663	ATP binding site [chemical binding]; other site
714313002664	Q-loop/lid; other site
714313002665	ABC transporter signature motif; other site
714313002666	Walker B; other site
714313002667	D-loop; other site
714313002668	H-loop/switch region; other site
714313002669	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
714313002670	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
714313002671	putative active site [active]
714313002672	metal binding site [ion binding]; metal-binding site
714313002673	homodimer binding site [polypeptide binding]; other site
714313002674	phosphodiesterase; Provisional; Region: PRK12704
714313002675	uncharacterized domain HDIG; Region: HDIG; TIGR00277
714313002676	competence damage-inducible protein A; Provisional; Region: PRK00549
714313002677	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
714313002678	putative MPT binding site; other site
714313002679	Competence-damaged protein; Region: CinA; pfam02464
714313002680	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
714313002681	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
714313002682	non-specific DNA binding site [nucleotide binding]; other site
714313002683	salt bridge; other site
714313002684	sequence-specific DNA binding site [nucleotide binding]; other site
714313002685	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
714313002686	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
714313002687	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
714313002688	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
714313002689	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
714313002690	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
714313002691	Switch I; other site
714313002692	Switch II; other site
714313002693	Septum formation inhibitor [Cell division and chromosome partitioning]; Region: MinC; COG0850
714313002694	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
714313002695	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
714313002696	rod shape-determining protein MreC; Provisional; Region: PRK13922
714313002697	rod shape-determining protein MreC; Region: MreC; pfam04085
714313002698	rod shape-determining protein MreB; Provisional; Region: PRK13927
714313002699	MreB and similar proteins; Region: MreB_like; cd10225
714313002700	nucleotide binding site [chemical binding]; other site
714313002701	Mg binding site [ion binding]; other site
714313002702	putative protofilament interaction site [polypeptide binding]; other site
714313002703	RodZ interaction site [polypeptide binding]; other site
714313002704	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
714313002705	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
714313002706	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
714313002707	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
714313002708	active site
714313002709	HIGH motif; other site
714313002710	nucleotide binding site [chemical binding]; other site
714313002711	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
714313002712	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
714313002713	active site
714313002714	KMSKS motif; other site
714313002715	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
714313002716	tRNA binding surface [nucleotide binding]; other site
714313002717	anticodon binding site; other site
714313002718	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
714313002719	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
714313002720	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
714313002721	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
714313002722	Ligand Binding Site [chemical binding]; other site
714313002723	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
714313002724	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
714313002725	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
714313002726	catalytic residue [active]
714313002727	Septation ring formation regulator, EzrA; Region: EzrA; pfam06160
714313002728	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
714313002729	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
714313002730	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
714313002731	RNA binding surface [nucleotide binding]; other site
714313002732	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
714313002733	recombination factor protein RarA; Reviewed; Region: PRK13342
714313002734	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313002735	Walker A motif; other site
714313002736	ATP binding site [chemical binding]; other site
714313002737	Walker B motif; other site
714313002738	arginine finger; other site
714313002739	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
714313002740	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
714313002741	Ligand Binding Site [chemical binding]; other site
714313002742	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
714313002743	non-specific DNA binding site [nucleotide binding]; other site
714313002744	salt bridge; other site
714313002745	sequence-specific DNA binding site [nucleotide binding]; other site
714313002746	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
714313002747	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
714313002748	ATP-grasp domain; Region: ATP-grasp_4; cl17255
714313002749	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
714313002750	Uncharacterized conserved protein [Function unknown]; Region: COG0759
714313002751	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
714313002752	rod shape-determining protein MreB; Provisional; Region: PRK13930
714313002753	MreB and similar proteins; Region: MreB_like; cd10225
714313002754	nucleotide binding site [chemical binding]; other site
714313002755	Mg binding site [ion binding]; other site
714313002756	putative protofilament interaction site [polypeptide binding]; other site
714313002757	RodZ interaction site [polypeptide binding]; other site
714313002758	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
714313002759	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
714313002760	hinge; other site
714313002761	active site
714313002762	Protein of unknown function (DUF1146); Region: DUF1146; pfam06612
714313002763	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
714313002764	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
714313002765	gamma subunit interface [polypeptide binding]; other site
714313002766	epsilon subunit interface [polypeptide binding]; other site
714313002767	LBP interface [polypeptide binding]; other site
714313002768	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
714313002769	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
714313002770	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
714313002771	alpha subunit interaction interface [polypeptide binding]; other site
714313002772	Walker A motif; other site
714313002773	ATP binding site [chemical binding]; other site
714313002774	Walker B motif; other site
714313002775	inhibitor binding site; inhibition site
714313002776	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
714313002777	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
714313002778	core domain interface [polypeptide binding]; other site
714313002779	delta subunit interface [polypeptide binding]; other site
714313002780	epsilon subunit interface [polypeptide binding]; other site
714313002781	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
714313002782	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
714313002783	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
714313002784	beta subunit interaction interface [polypeptide binding]; other site
714313002785	Walker A motif; other site
714313002786	ATP binding site [chemical binding]; other site
714313002787	Walker B motif; other site
714313002788	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
714313002789	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
714313002790	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
714313002791	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
714313002792	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
714313002793	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
714313002794	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
714313002795	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
714313002796	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313002797	active site
714313002798	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
714313002799	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
714313002800	dimer interface [polypeptide binding]; other site
714313002801	active site
714313002802	glycine-pyridoxal phosphate binding site [chemical binding]; other site
714313002803	folate binding site [chemical binding]; other site
714313002804	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
714313002805	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
714313002806	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
714313002807	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313002808	S-adenosylmethionine binding site [chemical binding]; other site
714313002809	peptide chain release factor 1; Validated; Region: prfA; PRK00591
714313002810	This domain is found in peptide chain release factors; Region: PCRF; smart00937
714313002811	RF-1 domain; Region: RF-1; pfam00472
714313002812	thymidine kinase; Provisional; Region: PRK04296
714313002813	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
714313002814	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
714313002815	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
714313002816	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
714313002817	catalytic triad [active]
714313002818	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313002819	active site
714313002820	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
714313002821	DHH family; Region: DHH; pfam01368
714313002822	DHHA1 domain; Region: DHHA1; pfam02272
714313002823	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
714313002824	ribonuclease Z; Region: RNase_Z; TIGR02651
714313002825	GTPase CgtA; Reviewed; Region: obgE; PRK12297
714313002826	GTP1/OBG; Region: GTP1_OBG; pfam01018
714313002827	Obg GTPase; Region: Obg; cd01898
714313002828	G1 box; other site
714313002829	GTP/Mg2+ binding site [chemical binding]; other site
714313002830	Switch I region; other site
714313002831	G2 box; other site
714313002832	G3 box; other site
714313002833	Switch II region; other site
714313002834	G4 box; other site
714313002835	G5 box; other site
714313002836	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
714313002837	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
714313002838	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
714313002839	GIY-YIG motif/motif A; other site
714313002840	active site
714313002841	catalytic site [active]
714313002842	putative DNA binding site [nucleotide binding]; other site
714313002843	metal binding site [ion binding]; metal-binding site
714313002844	UvrB/uvrC motif; Region: UVR; pfam02151
714313002845	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
714313002846	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
714313002847	G1 box; other site
714313002848	GTP/Mg2+ binding site [chemical binding]; other site
714313002849	Switch I region; other site
714313002850	G2 box; other site
714313002851	G3 box; other site
714313002852	Switch II region; other site
714313002853	G4 box; other site
714313002854	G5 box; other site
714313002855	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
714313002856	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
714313002857	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313002858	Walker A motif; other site
714313002859	ATP binding site [chemical binding]; other site
714313002860	Walker B motif; other site
714313002861	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
714313002862	trigger factor; Provisional; Region: tig; PRK01490
714313002863	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
714313002864	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
714313002865	elongation factor Tu; Reviewed; Region: PRK00049
714313002866	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
714313002867	G1 box; other site
714313002868	GEF interaction site [polypeptide binding]; other site
714313002869	GTP/Mg2+ binding site [chemical binding]; other site
714313002870	Switch I region; other site
714313002871	G2 box; other site
714313002872	G3 box; other site
714313002873	Switch II region; other site
714313002874	G4 box; other site
714313002875	G5 box; other site
714313002876	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
714313002877	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
714313002878	Antibiotic Binding Site [chemical binding]; other site
714313002879	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
714313002880	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
714313002881	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
714313002882	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
714313002883	16S/18S rRNA binding site [nucleotide binding]; other site
714313002884	S13e-L30e interaction site [polypeptide binding]; other site
714313002885	25S rRNA binding site [nucleotide binding]; other site
714313002886	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
714313002887	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
714313002888	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
714313002889	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
714313002890	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
714313002891	Competence protein; Region: Competence; pfam03772
714313002892	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
714313002893	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
714313002894	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
714313002895	catalytic motif [active]
714313002896	Zn binding site [ion binding]; other site
714313002897	SLBB domain; Region: SLBB; pfam10531
714313002898	comEA protein; Region: comE; TIGR01259
714313002899	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
714313002900	Coenzyme A binding pocket [chemical binding]; other site
714313002901	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
714313002902	catalytic residues [active]
714313002903	dimer interface [polypeptide binding]; other site
714313002904	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
714313002905	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
714313002906	protein binding site [polypeptide binding]; other site
714313002907	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
714313002908	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
714313002909	active site
714313002910	(T/H)XGH motif; other site
714313002911	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
714313002912	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313002913	S-adenosylmethionine binding site [chemical binding]; other site
714313002914	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; pfam09902
714313002915	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
714313002916	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
714313002917	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
714313002918	G1 box; other site
714313002919	putative GEF interaction site [polypeptide binding]; other site
714313002920	GTP/Mg2+ binding site [chemical binding]; other site
714313002921	Switch I region; other site
714313002922	G2 box; other site
714313002923	G3 box; other site
714313002924	Switch II region; other site
714313002925	G4 box; other site
714313002926	G5 box; other site
714313002927	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
714313002928	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
714313002929	Uncharacterized protein family (UPF0223); Region: UPF0223; cl11484
714313002930	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
714313002931	substrate binding site [chemical binding]; other site
714313002932	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
714313002933	active site
714313002934	catalytic residues [active]
714313002935	metal binding site [ion binding]; metal-binding site
714313002936	hypothetical protein; Provisional; Region: PRK13667
714313002937	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
714313002938	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
714313002939	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
714313002940	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
714313002941	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
714313002942	active site
714313002943	catalytic tetrad [active]
714313002944	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
714313002945	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
714313002946	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313002947	active site
714313002948	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
714313002949	AAA domain; Region: AAA_30; pfam13604
714313002950	Family description; Region: UvrD_C_2; pfam13538
714313002951	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
714313002952	binding surface
714313002953	TPR motif; other site
714313002954	Tetratricopeptide repeat; Region: TPR_12; pfam13424
714313002955	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
714313002956	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
714313002957	binding surface
714313002958	TPR motif; other site
714313002959	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313002960	catalytic core [active]
714313002961	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
714313002962	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
714313002963	Putative amino acid metabolism; Region: DUF1831; pfam08866
714313002964	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
714313002965	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
714313002966	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
714313002967	catalytic residue [active]
714313002968	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
714313002969	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
714313002970	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
714313002971	dimer interface [polypeptide binding]; other site
714313002972	ADP-ribose binding site [chemical binding]; other site
714313002973	active site
714313002974	nudix motif; other site
714313002975	metal binding site [ion binding]; metal-binding site
714313002976	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
714313002977	DNA-binding site [nucleotide binding]; DNA binding site
714313002978	RNA-binding motif; other site
714313002979	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
714313002980	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
714313002981	active site
714313002982	HIGH motif; other site
714313002983	nucleotide binding site [chemical binding]; other site
714313002984	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
714313002985	active site
714313002986	KMSKS motif; other site
714313002987	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
714313002988	tRNA binding surface [nucleotide binding]; other site
714313002989	anticodon binding site; other site
714313002990	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
714313002991	DivIVA protein; Region: DivIVA; pfam05103
714313002992	DivIVA domain; Region: DivI1A_domain; TIGR03544
714313002993	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
714313002994	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
714313002995	RNA binding surface [nucleotide binding]; other site
714313002996	YGGT family; Region: YGGT; pfam02325
714313002997	Protein of unknown function (DUF552); Region: DUF552; pfam04472
714313002998	cell division protein FtsZ; Validated; Region: PRK09330
714313002999	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
714313003000	nucleotide binding site [chemical binding]; other site
714313003001	SulA interaction site; other site
714313003002	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
714313003003	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
714313003004	nucleotide binding site [chemical binding]; other site
714313003005	SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491
714313003006	Cell division protein FtsA; Region: FtsA; pfam14450
714313003007	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
714313003008	Cell division protein FtsQ; Region: FtsQ; pfam03799
714313003009	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
714313003010	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
714313003011	active site
714313003012	homodimer interface [polypeptide binding]; other site
714313003013	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
714313003014	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
714313003015	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
714313003016	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
714313003017	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
714313003018	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
714313003019	Mg++ binding site [ion binding]; other site
714313003020	putative catalytic motif [active]
714313003021	putative substrate binding site [chemical binding]; other site
714313003022	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
714313003023	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
714313003024	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
714313003025	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
714313003026	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
714313003027	MraW methylase family; Region: Methyltransf_5; pfam01795
714313003028	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
714313003029	cell division protein MraZ; Reviewed; Region: PRK00326
714313003030	MraZ protein; Region: MraZ; pfam02381
714313003031	MraZ protein; Region: MraZ; pfam02381
714313003032	Protein of unknown function (DUF4044); Region: DUF4044; pfam13253
714313003033	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313003034	putative substrate translocation pore; other site
714313003035	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
714313003036	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
714313003037	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
714313003038	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
714313003039	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
714313003040	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
714313003041	active site
714313003042	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
714313003043	ATP-NAD kinase; Region: NAD_kinase; pfam01513
714313003044	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
714313003045	synthetase active site [active]
714313003046	NTP binding site [chemical binding]; other site
714313003047	metal binding site [ion binding]; metal-binding site
714313003048	Thioredoxin; Region: Thioredoxin_5; pfam13743
714313003049	oligoendopeptidase F; Region: pepF; TIGR00181
714313003050	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
714313003051	active site
714313003052	Zn binding site [ion binding]; other site
714313003053	Competence protein CoiA-like family; Region: CoiA; cl11541
714313003054	Negative regulator of genetic competence (MecA); Region: MecA; cl02022
714313003055	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
714313003056	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
714313003057	HTH-like domain; Region: HTH_21; pfam13276
714313003058	Integrase core domain; Region: rve; pfam00665
714313003059	Integrase core domain; Region: rve_2; pfam13333
714313003060	Homeodomain-like domain; Region: HTH_23; cl17451
714313003061	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003062	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
714313003063	Sulfatase; Region: Sulfatase; pfam00884
714313003064	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
714313003065	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
714313003066	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
714313003067	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
714313003068	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
714313003069	putative ADP-binding pocket [chemical binding]; other site
714313003070	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
714313003071	dimerization domain swap beta strand [polypeptide binding]; other site
714313003072	regulatory protein interface [polypeptide binding]; other site
714313003073	active site
714313003074	regulatory phosphorylation site [posttranslational modification]; other site
714313003075	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313003076	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
714313003077	Walker A motif; other site
714313003078	ATP binding site [chemical binding]; other site
714313003079	Walker B motif; other site
714313003080	arginine finger; other site
714313003081	UvrB/uvrC motif; Region: UVR; pfam02151
714313003082	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313003083	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
714313003084	Walker A motif; other site
714313003085	ATP binding site [chemical binding]; other site
714313003086	Walker B motif; other site
714313003087	arginine finger; other site
714313003088	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
714313003089	HTH-like domain; Region: HTH_21; pfam13276
714313003090	Integrase core domain; Region: rve; pfam00665
714313003091	Integrase core domain; Region: rve_2; pfam13333
714313003092	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003093	Homeodomain-like domain; Region: HTH_23; cl17451
714313003094	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003095	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
714313003096	argininosuccinate synthase; Provisional; Region: PRK13820
714313003097	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
714313003098	ANP binding site [chemical binding]; other site
714313003099	Substrate Binding Site II [chemical binding]; other site
714313003100	Substrate Binding Site I [chemical binding]; other site
714313003101	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
714313003102	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
714313003103	Walker A/P-loop; other site
714313003104	ATP binding site [chemical binding]; other site
714313003105	Q-loop/lid; other site
714313003106	ABC transporter signature motif; other site
714313003107	Walker B; other site
714313003108	D-loop; other site
714313003109	H-loop/switch region; other site
714313003110	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
714313003111	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
714313003112	substrate binding pocket [chemical binding]; other site
714313003113	membrane-bound complex binding site; other site
714313003114	hinge residues; other site
714313003115	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313003116	dimer interface [polypeptide binding]; other site
714313003117	conserved gate region; other site
714313003118	ABC-ATPase subunit interface; other site
714313003119	BioY family; Region: BioY; pfam02632
714313003120	Peptidase family C69; Region: Peptidase_C69; pfam03577
714313003121	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
714313003122	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
714313003123	G1 box; other site
714313003124	putative GEF interaction site [polypeptide binding]; other site
714313003125	GTP/Mg2+ binding site [chemical binding]; other site
714313003126	Switch I region; other site
714313003127	G2 box; other site
714313003128	G3 box; other site
714313003129	Switch II region; other site
714313003130	G4 box; other site
714313003131	G5 box; other site
714313003132	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
714313003133	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
714313003134	Domain of unknown function DUF20; Region: UPF0118; pfam01594
714313003135	RecX family; Region: RecX; cl00936
714313003136	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
714313003137	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
714313003138	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
714313003139	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
714313003140	Ligand binding site; other site
714313003141	Putative Catalytic site; other site
714313003142	DXD motif; other site
714313003143	Predicted membrane protein [Function unknown]; Region: COG2246
714313003144	GtrA-like protein; Region: GtrA; pfam04138
714313003145	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003146	Homeodomain-like domain; Region: HTH_23; cl17451
714313003147	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003148	HTH-like domain; Region: HTH_21; pfam13276
714313003149	Integrase core domain; Region: rve; pfam00665
714313003150	Integrase core domain; Region: rve_2; pfam13333
714313003151	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
714313003152	DEAD-like helicases superfamily; Region: DEXDc; smart00487
714313003153	ATP binding site [chemical binding]; other site
714313003154	putative Mg++ binding site [ion binding]; other site
714313003155	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
714313003156	nucleotide binding region [chemical binding]; other site
714313003157	ATP-binding site [chemical binding]; other site
714313003158	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
714313003159	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
714313003160	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
714313003161	active site
714313003162	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
714313003163	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
714313003164	N- and C-terminal domain interface [polypeptide binding]; other site
714313003165	active site
714313003166	catalytic site [active]
714313003167	metal binding site [ion binding]; metal-binding site
714313003168	carbohydrate binding site [chemical binding]; other site
714313003169	ATP binding site [chemical binding]; other site
714313003170	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
714313003171	non-specific DNA binding site [nucleotide binding]; other site
714313003172	salt bridge; other site
714313003173	sequence-specific DNA binding site [nucleotide binding]; other site
714313003174	hypothetical protein; Provisional; Region: PRK04435
714313003175	C-terminal ACT domain of a small (; 147 a.a.) putative phenylalanine biosynthetic pathway protein described in Bacillus subtilis (BS) PheB (PheB-BS) and related domains; Region: ACT_PheB-BS; cd04888
714313003176	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
714313003177	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
714313003178	metal binding site [ion binding]; metal-binding site
714313003179	dimer interface [polypeptide binding]; other site
714313003180	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
714313003181	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
714313003182	Coenzyme A binding pocket [chemical binding]; other site
714313003183	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
714313003184	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003185	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003186	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003187	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003188	putative transposase OrfB; Reviewed; Region: PHA02517
714313003189	HTH-like domain; Region: HTH_21; pfam13276
714313003190	Integrase core domain; Region: rve; pfam00665
714313003191	Integrase core domain; Region: rve_2; pfam13333
714313003192	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
714313003193	Integrase core domain; Region: rve; pfam00665
714313003194	Mrr N-terminal domain; Region: Mrr_N; pfam14338
714313003195	Restriction endonuclease; Region: Mrr_cat; pfam04471
714313003196	TRAM domain; Region: TRAM; pfam01938
714313003197	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
714313003198	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
714313003199	S-adenosylmethionine binding site [chemical binding]; other site
714313003200	putative lipid kinase; Reviewed; Region: PRK13055
714313003201	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
714313003202	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
714313003203	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
714313003204	GatB domain; Region: GatB_Yqey; smart00845
714313003205	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
714313003206	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
714313003207	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
714313003208	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
714313003209	putative dimer interface [polypeptide binding]; other site
714313003210	CamS sex pheromone cAM373 precursor; Region: CamS; pfam07537
714313003211	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
714313003212	putative dimer interface [polypeptide binding]; other site
714313003213	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
714313003214	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
714313003215	nucleotide binding pocket [chemical binding]; other site
714313003216	K-X-D-G motif; other site
714313003217	catalytic site [active]
714313003218	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
714313003219	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
714313003220	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
714313003221	Dimer interface [polypeptide binding]; other site
714313003222	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
714313003223	Part of AAA domain; Region: AAA_19; pfam13245
714313003224	Family description; Region: UvrD_C_2; pfam13538
714313003225	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
714313003226	ATP-grasp domain; Region: ATP-grasp_4; cl17255
714313003227	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
714313003228	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
714313003229	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
714313003230	putative metal binding site [ion binding]; other site
714313003231	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
714313003232	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
714313003233	D-lactate dehydrogenase; Provisional; Region: PRK11183
714313003234	FAD binding domain; Region: FAD_binding_4; pfam01565
714313003235	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
714313003236	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
714313003237	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
714313003238	23S rRNA interface [nucleotide binding]; other site
714313003239	L3 interface [polypeptide binding]; other site
714313003240	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
714313003241	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
714313003242	dimerization interface 3.5A [polypeptide binding]; other site
714313003243	active site
714313003244	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
714313003245	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13649
714313003246	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
714313003247	Walker A/P-loop; other site
714313003248	ATP binding site [chemical binding]; other site
714313003249	Q-loop/lid; other site
714313003250	ABC transporter signature motif; other site
714313003251	Walker B; other site
714313003252	D-loop; other site
714313003253	H-loop/switch region; other site
714313003254	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
714313003255	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
714313003256	Walker A/P-loop; other site
714313003257	ATP binding site [chemical binding]; other site
714313003258	Q-loop/lid; other site
714313003259	ABC transporter signature motif; other site
714313003260	Walker B; other site
714313003261	D-loop; other site
714313003262	H-loop/switch region; other site
714313003263	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
714313003264	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
714313003265	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
714313003266	alphaNTD homodimer interface [polypeptide binding]; other site
714313003267	alphaNTD - beta interaction site [polypeptide binding]; other site
714313003268	alphaNTD - beta' interaction site [polypeptide binding]; other site
714313003269	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
714313003270	30S ribosomal protein S11; Validated; Region: PRK05309
714313003271	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
714313003272	30S ribosomal protein S13; Region: bact_S13; TIGR03631
714313003273	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
714313003274	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
714313003275	rRNA binding site [nucleotide binding]; other site
714313003276	predicted 30S ribosome binding site; other site
714313003277	adenylate kinase; Reviewed; Region: adk; PRK00279
714313003278	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
714313003279	AMP-binding site [chemical binding]; other site
714313003280	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
714313003281	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
714313003282	SecY translocase; Region: SecY; pfam00344
714313003283	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
714313003284	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
714313003285	23S rRNA binding site [nucleotide binding]; other site
714313003286	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
714313003287	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
714313003288	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
714313003289	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
714313003290	5S rRNA interface [nucleotide binding]; other site
714313003291	L27 interface [polypeptide binding]; other site
714313003292	23S rRNA interface [nucleotide binding]; other site
714313003293	L5 interface [polypeptide binding]; other site
714313003294	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
714313003295	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
714313003296	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
714313003297	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
714313003298	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
714313003299	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
714313003300	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
714313003301	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
714313003302	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
714313003303	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
714313003304	RNA binding site [nucleotide binding]; other site
714313003305	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
714313003306	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
714313003307	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
714313003308	23S rRNA interface [nucleotide binding]; other site
714313003309	putative translocon interaction site; other site
714313003310	signal recognition particle (SRP54) interaction site; other site
714313003311	L23 interface [polypeptide binding]; other site
714313003312	trigger factor interaction site; other site
714313003313	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
714313003314	23S rRNA interface [nucleotide binding]; other site
714313003315	5S rRNA interface [nucleotide binding]; other site
714313003316	putative antibiotic binding site [chemical binding]; other site
714313003317	L25 interface [polypeptide binding]; other site
714313003318	L27 interface [polypeptide binding]; other site
714313003319	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
714313003320	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
714313003321	G-X-X-G motif; other site
714313003322	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
714313003323	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
714313003324	putative translocon binding site; other site
714313003325	protein-rRNA interface [nucleotide binding]; other site
714313003326	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
714313003327	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
714313003328	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
714313003329	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
714313003330	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
714313003331	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
714313003332	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
714313003333	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
714313003334	elongation factor G; Reviewed; Region: PRK12739
714313003335	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
714313003336	G1 box; other site
714313003337	putative GEF interaction site [polypeptide binding]; other site
714313003338	GTP/Mg2+ binding site [chemical binding]; other site
714313003339	Switch I region; other site
714313003340	G2 box; other site
714313003341	G3 box; other site
714313003342	Switch II region; other site
714313003343	G4 box; other site
714313003344	G5 box; other site
714313003345	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
714313003346	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
714313003347	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
714313003348	30S ribosomal protein S7; Validated; Region: PRK05302
714313003349	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
714313003350	S17 interaction site [polypeptide binding]; other site
714313003351	S8 interaction site; other site
714313003352	16S rRNA interaction site [nucleotide binding]; other site
714313003353	streptomycin interaction site [chemical binding]; other site
714313003354	23S rRNA interaction site [nucleotide binding]; other site
714313003355	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
714313003356	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
714313003357	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
714313003358	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313003359	active site
714313003360	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
714313003361	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
714313003362	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
714313003363	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
714313003364	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
714313003365	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
714313003366	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
714313003367	DNA binding site [nucleotide binding]
714313003368	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
714313003369	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
714313003370	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
714313003371	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
714313003372	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
714313003373	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
714313003374	RPB1 interaction site [polypeptide binding]; other site
714313003375	RPB11 interaction site [polypeptide binding]; other site
714313003376	RPB12 interaction site [polypeptide binding]; other site
714313003377	RPB10 interaction site [polypeptide binding]; other site
714313003378	RPB11 interaction site [polypeptide binding]; other site
714313003379	RPB3 interaction site [polypeptide binding]; other site
714313003380	RPB12 interaction site [polypeptide binding]; other site
714313003381	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
714313003382	Clp amino terminal domain; Region: Clp_N; pfam02861
714313003383	Clp amino terminal domain; Region: Clp_N; pfam02861
714313003384	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313003385	Walker A motif; other site
714313003386	ATP binding site [chemical binding]; other site
714313003387	Walker B motif; other site
714313003388	arginine finger; other site
714313003389	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313003390	Walker A motif; other site
714313003391	ATP binding site [chemical binding]; other site
714313003392	Walker B motif; other site
714313003393	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
714313003394	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
714313003395	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
714313003396	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
714313003397	tetramer (dimer of dimers) interface [polypeptide binding]; other site
714313003398	NAD binding site [chemical binding]; other site
714313003399	dimer interface [polypeptide binding]; other site
714313003400	substrate binding site [chemical binding]; other site
714313003401	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
714313003402	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; cl07696
714313003403	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
714313003404	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
714313003405	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313003406	dimer interface [polypeptide binding]; other site
714313003407	conserved gate region; other site
714313003408	putative PBP binding loops; other site
714313003409	ABC-ATPase subunit interface; other site
714313003410	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
714313003411	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313003412	dimer interface [polypeptide binding]; other site
714313003413	conserved gate region; other site
714313003414	ABC-ATPase subunit interface; other site
714313003415	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
714313003416	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
714313003417	Walker A/P-loop; other site
714313003418	ATP binding site [chemical binding]; other site
714313003419	Q-loop/lid; other site
714313003420	ABC transporter signature motif; other site
714313003421	Walker B; other site
714313003422	D-loop; other site
714313003423	H-loop/switch region; other site
714313003424	seryl-tRNA synthetase; Provisional; Region: PRK05431
714313003425	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
714313003426	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
714313003427	dimer interface [polypeptide binding]; other site
714313003428	active site
714313003429	motif 1; other site
714313003430	motif 2; other site
714313003431	motif 3; other site
714313003432	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
714313003433	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
714313003434	Substrate-binding site [chemical binding]; other site
714313003435	Substrate specificity [chemical binding]; other site
714313003436	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
714313003437	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
714313003438	SEC10/PgrA surface exclusion domain; Region: Surf_Exclu_PgrA; TIGR04320
714313003439	SEC10/PgrA surface exclusion domain; Region: Surf_Exclu_PgrA; TIGR04320
714313003440	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
714313003441	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
714313003442	active site
714313003443	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
714313003444	Protein of unknown function (DUF1634); Region: DUF1634; pfam07843
714313003445	HTH-like domain; Region: HTH_21; pfam13276
714313003446	Integrase core domain; Region: rve; pfam00665
714313003447	Integrase core domain; Region: rve_2; pfam13333
714313003448	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003449	Homeodomain-like domain; Region: HTH_23; cl17451
714313003450	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003451	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
714313003452	metal binding site [ion binding]; metal-binding site
714313003453	dimer interface [polypeptide binding]; other site
714313003454	amidophosphoribosyltransferase; Region: PLN02440
714313003455	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
714313003456	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
714313003457	active site
714313003458	DNA binding site [nucleotide binding]
714313003459	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
714313003460	Ligand Binding Site [chemical binding]; other site
714313003461	BCCT family transporter; Region: BCCT; pfam02028
714313003462	maltose O-acetyltransferase; Provisional; Region: PRK10092
714313003463	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
714313003464	active site
714313003465	substrate binding site [chemical binding]; other site
714313003466	trimer interface [polypeptide binding]; other site
714313003467	CoA binding site [chemical binding]; other site
714313003468	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
714313003469	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
714313003470	RNA/DNA hybrid binding site [nucleotide binding]; other site
714313003471	active site
714313003472	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
714313003473	dimer interface [polypeptide binding]; other site
714313003474	substrate binding site [chemical binding]; other site
714313003475	ATP binding site [chemical binding]; other site
714313003476	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
714313003477	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
714313003478	DNA-binding site [nucleotide binding]; DNA binding site
714313003479	RNA-binding motif; other site
714313003480	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
714313003481	DNA-binding site [nucleotide binding]; DNA binding site
714313003482	RNA-binding motif; other site
714313003483	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
714313003484	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
714313003485	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
714313003486	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
714313003487	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06079
714313003488	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
714313003489	NAD binding site [chemical binding]; other site
714313003490	homotetramer interface [polypeptide binding]; other site
714313003491	homodimer interface [polypeptide binding]; other site
714313003492	substrate binding site [chemical binding]; other site
714313003493	active site
714313003494	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
714313003495	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
714313003496	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
714313003497	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
714313003498	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
714313003499	ATP-grasp domain; Region: ATP-grasp_4; cl17255
714313003500	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
714313003501	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
714313003502	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
714313003503	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
714313003504	carboxyltransferase (CT) interaction site; other site
714313003505	biotinylation site [posttranslational modification]; other site
714313003506	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
714313003507	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
714313003508	dimer interface [polypeptide binding]; other site
714313003509	active site
714313003510	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
714313003511	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
714313003512	NAD(P) binding site [chemical binding]; other site
714313003513	active site
714313003514	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
714313003515	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
714313003516	Phosphopantetheine attachment site; Region: PP-binding; cl09936
714313003517	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
714313003518	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
714313003519	dimer interface [polypeptide binding]; other site
714313003520	active site
714313003521	CoA binding pocket [chemical binding]; other site
714313003522	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
714313003523	Predicted membrane protein [Function unknown]; Region: COG2364
714313003524	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
714313003525	fumarate hydratase; Reviewed; Region: fumC; PRK00485
714313003526	Class II fumarases; Region: Fumarase_classII; cd01362
714313003527	active site
714313003528	tetramer interface [polypeptide binding]; other site
714313003529	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
714313003530	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
714313003531	GDP-binding site [chemical binding]; other site
714313003532	ACT binding site; other site
714313003533	IMP binding site; other site
714313003534	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
714313003535	acyl carrier protein; Provisional; Region: acpP; PRK00982
714313003536	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
714313003537	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
714313003538	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313003539	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313003540	Probable transposase; Region: OrfB_IS605; pfam01385
714313003541	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313003542	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313003543	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
714313003544	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
714313003545	active site
714313003546	catalytic tetrad [active]
714313003547	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003548	Homeodomain-like domain; Region: HTH_23; cl17451
714313003549	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003550	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
714313003551	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
714313003552	NAD binding site [chemical binding]; other site
714313003553	substrate binding site [chemical binding]; other site
714313003554	catalytic Zn binding site [ion binding]; other site
714313003555	tetramer interface [polypeptide binding]; other site
714313003556	structural Zn binding site [ion binding]; other site
714313003557	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
714313003558	active site
714313003559	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
714313003560	active site
714313003561	dimer interface [polypeptide binding]; other site
714313003562	benzoate transport; Region: 2A0115; TIGR00895
714313003563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313003564	putative substrate translocation pore; other site
714313003565	arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810
714313003566	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
714313003567	EamA-like transporter family; Region: EamA; cl17759
714313003568	EamA-like transporter family; Region: EamA; pfam00892
714313003569	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
714313003570	EamA-like transporter family; Region: EamA; pfam00892
714313003571	EamA-like transporter family; Region: EamA; pfam00892
714313003572	Transport protein; Region: actII; TIGR00833
714313003573	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
714313003574	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
714313003575	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
714313003576	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
714313003577	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
714313003578	NAD binding site [chemical binding]; other site
714313003579	homodimer interface [polypeptide binding]; other site
714313003580	active site
714313003581	substrate binding site [chemical binding]; other site
714313003582	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
714313003583	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
714313003584	active site
714313003585	substrate binding site [chemical binding]; other site
714313003586	metal binding site [ion binding]; metal-binding site
714313003587	stage V sporulation protein K; Region: spore_V_K; TIGR02881
714313003588	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313003589	Walker A motif; other site
714313003590	ATP binding site [chemical binding]; other site
714313003591	Walker B motif; other site
714313003592	arginine finger; other site
714313003593	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
714313003594	putative substrate translocation pore; other site
714313003595	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
714313003596	catalytic core [active]
714313003597	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
714313003598	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein; Region: PTPS_related; pfam10131
714313003599	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
714313003600	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
714313003601	NAD(P) binding site [chemical binding]; other site
714313003602	active site
714313003603	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003604	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003605	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003606	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003607	putative transposase OrfB; Reviewed; Region: PHA02517
714313003608	HTH-like domain; Region: HTH_21; pfam13276
714313003609	Integrase core domain; Region: rve; pfam00665
714313003610	Integrase core domain; Region: rve_2; pfam13333
714313003611	inner membrane transporter YjeM; Provisional; Region: PRK15238
714313003612	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
714313003613	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
714313003614	DNA binding site [nucleotide binding]
714313003615	active site
714313003616	Predicted membrane protein (DUF2157); Region: DUF2157; cl10480
714313003617	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
714313003618	dimer interface [polypeptide binding]; other site
714313003619	FMN binding site [chemical binding]; other site
714313003620	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
714313003621	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
714313003622	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
714313003623	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
714313003624	NAD binding site [chemical binding]; other site
714313003625	Bacterial sugar transferase; Region: Bac_transf; pfam02397
714313003626	Core-2/I-Branching enzyme; Region: Branch; pfam02485
714313003627	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
714313003628	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
714313003629	UDP-galactopyranose mutase; Region: GLF; pfam03275
714313003630	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
714313003631	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
714313003632	putative ADP-binding pocket [chemical binding]; other site
714313003633	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
714313003634	active site
714313003635	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003636	Homeodomain-like domain; Region: HTH_23; cl17451
714313003637	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003638	HTH-like domain; Region: HTH_21; pfam13276
714313003639	Integrase core domain; Region: rve; pfam00665
714313003640	Integrase core domain; Region: rve_2; pfam13333
714313003641	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
714313003642	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
714313003643	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
714313003644	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
714313003645	UDP-galactopyranose mutase; Region: GLF; pfam03275
714313003646	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
714313003647	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_b; cd04185
714313003648	Probable Catalytic site; other site
714313003649	Domain of unknown function (DUF4422); Region: DUF4422; pfam14393
714313003650	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
714313003651	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313003652	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
714313003653	Walker A motif; other site
714313003654	ATP binding site [chemical binding]; other site
714313003655	Walker B motif; other site
714313003656	arginine finger; other site
714313003657	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
714313003658	Walker A motif; other site
714313003659	ATP binding site [chemical binding]; other site
714313003660	Walker B motif; other site
714313003661	arginine finger; other site
714313003662	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
714313003663	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
714313003664	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
714313003665	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
714313003666	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
714313003667	Chain length determinant protein; Region: Wzz; cl15801
714313003668	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
714313003669	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
714313003670	active site
714313003671	tetramer interface; other site
714313003672	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
714313003673	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
714313003674	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
714313003675	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313003676	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313003677	Probable transposase; Region: OrfB_IS605; pfam01385
714313003678	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313003679	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313003680	Cadmium resistance transporter; Region: Cad; pfam03596
714313003681	Winged helix-turn helix; Region: HTH_29; pfam13551
714313003682	HTH-like domain; Region: HTH_21; pfam13276
714313003683	Integrase core domain; Region: rve; pfam00665
714313003684	DDE domain; Region: DDE_Tnp_IS240; pfam13610
714313003685	Integrase core domain; Region: rve_2; pfam13333
714313003686	Predicted transcriptional regulators [Transcription]; Region: COG1733
714313003687	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
714313003688	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
714313003689	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
714313003690	active site
714313003691	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
714313003692	glycerate kinase; Region: TIGR00045
714313003693	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
714313003694	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
714313003695	CoenzymeA binding site [chemical binding]; other site
714313003696	subunit interaction site [polypeptide binding]; other site
714313003697	PHB binding site; other site
714313003698	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
714313003699	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
714313003700	substrate binding site [chemical binding]; other site
714313003701	oxyanion hole (OAH) forming residues; other site
714313003702	trimer interface [polypeptide binding]; other site
714313003703	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
714313003704	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
714313003705	acyl-activating enzyme (AAE) consensus motif; other site
714313003706	putative AMP binding site [chemical binding]; other site
714313003707	putative active site [active]
714313003708	putative CoA binding site [chemical binding]; other site
714313003709	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
714313003710	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
714313003711	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
714313003712	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
714313003713	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
714313003714	citrate lyase subunit gamma; Provisional; Region: PRK13253
714313003715	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
714313003716	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
714313003717	active site
714313003718	nucleotide binding site [chemical binding]; other site
714313003719	HIGH motif; other site
714313003720	KMSKS motif; other site
714313003721	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
714313003722	Malic enzyme, N-terminal domain; Region: malic; pfam00390
714313003723	Malic enzyme, NAD binding domain; Region: Malic_M; smart00919
714313003724	NAD(P) binding pocket [chemical binding]; other site
714313003725	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
714313003726	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
714313003727	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
714313003728	NAD binding site [chemical binding]; other site
714313003729	dimer interface [polypeptide binding]; other site
714313003730	tetramer (dimer of dimers) interface [polypeptide binding]; other site
714313003731	substrate binding site [chemical binding]; other site
714313003732	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
714313003733	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
714313003734	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
714313003735	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
714313003736	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
714313003737	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
714313003738	Walker A/P-loop; other site
714313003739	ATP binding site [chemical binding]; other site
714313003740	Q-loop/lid; other site
714313003741	ABC transporter signature motif; other site
714313003742	Walker B; other site
714313003743	D-loop; other site
714313003744	H-loop/switch region; other site
714313003745	xanthine permease; Region: pbuX; TIGR03173
714313003746	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003747	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003748	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003749	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003750	Haemolysin-III related; Region: HlyIII; cl03831
714313003751	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
714313003752	LytTr DNA-binding domain; Region: LytTR; smart00850
714313003753	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
714313003754	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
714313003755	Transferrin; Region: Transferrin; cl02460
714313003756	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
714313003757	membrane-bound complex binding site; other site
714313003758	Predicted membrane protein [Function unknown]; Region: COG2855
714313003759	Transcriptional regulator [Transcription]; Region: LysR; COG0583
714313003760	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
714313003761	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
714313003762	dimerization interface [polypeptide binding]; other site
714313003763	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
714313003764	Part of AAA domain; Region: AAA_19; pfam13245
714313003765	Family description; Region: UvrD_C_2; pfam13538
714313003766	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
714313003767	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
714313003768	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
714313003769	NADH(P)-binding; Region: NAD_binding_10; pfam13460
714313003770	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
714313003771	NAD(P) binding site [chemical binding]; other site
714313003772	active site
714313003773	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
714313003774	HTH-like domain; Region: HTH_21; pfam13276
714313003775	Integrase core domain; Region: rve; pfam00665
714313003776	Integrase core domain; Region: rve_2; pfam13333
714313003777	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003778	Homeodomain-like domain; Region: HTH_23; cl17451
714313003779	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003780	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
714313003781	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313003782	dimer interface [polypeptide binding]; other site
714313003783	conserved gate region; other site
714313003784	putative PBP binding loops; other site
714313003785	ABC-ATPase subunit interface; other site
714313003786	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
714313003787	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
714313003788	dimer interface [polypeptide binding]; other site
714313003789	conserved gate region; other site
714313003790	putative PBP binding loops; other site
714313003791	ABC-ATPase subunit interface; other site
714313003792	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
714313003793	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
714313003794	substrate binding pocket [chemical binding]; other site
714313003795	membrane-bound complex binding site; other site
714313003796	hinge residues; other site
714313003797	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
714313003798	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
714313003799	Walker A/P-loop; other site
714313003800	ATP binding site [chemical binding]; other site
714313003801	Q-loop/lid; other site
714313003802	ABC transporter signature motif; other site
714313003803	Walker B; other site
714313003804	D-loop; other site
714313003805	H-loop/switch region; other site
714313003806	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
714313003807	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
714313003808	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
714313003809	putative active site [active]
714313003810	catalytic site [active]
714313003811	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
714313003812	putative active site [active]
714313003813	catalytic site [active]
714313003814	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
714313003815	trimer interface [polypeptide binding]; other site
714313003816	active site
714313003817	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
714313003818	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
714313003819	Catalytic site [active]
714313003820	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
714313003821	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
714313003822	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
714313003823	substrate binding pocket [chemical binding]; other site
714313003824	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
714313003825	EamA-like transporter family; Region: EamA; pfam00892
714313003826	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
714313003827	Transcriptional regulator [Transcription]; Region: LysR; COG0583
714313003828	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
714313003829	dimerization interface [polypeptide binding]; other site
714313003830	PemK-like protein; Region: PemK; cl00995
714313003831	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
714313003832	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
714313003833	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
714313003834	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
714313003835	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
714313003836	trmE is a tRNA modification GTPase; Region: trmE; cd04164
714313003837	G1 box; other site
714313003838	GTP/Mg2+ binding site [chemical binding]; other site
714313003839	Switch I region; other site
714313003840	G2 box; other site
714313003841	Switch II region; other site
714313003842	G3 box; other site
714313003843	G4 box; other site
714313003844	G5 box; other site
714313003845	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
714313003846	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
714313003847	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
714313003848	G-X-X-G motif; other site
714313003849	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
714313003850	RxxxH motif; other site
714313003851	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
714313003852	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
714313003853	ribonuclease P; Reviewed; Region: rnpA; PRK00499
714313003854	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
714313003855	Primase C terminal 1 (PriCT-1); Region: PriCT_1; pfam08708
714313003856	Alba; Region: Alba; cl00682
714313003857	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
714313003858	Transposase IS200 like; Region: Y1_Tnp; pfam01797
714313003859	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
714313003860	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
714313003861	Probable transposase; Region: OrfB_IS605; pfam01385
714313003862	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313003863	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
714313003864	CrcB-like protein; Region: CRCB; pfam02537
714313003865	CrcB-like protein; Region: CRCB; cl09114
714313003866	Integrase core domain; Region: rve; pfam00665
714313003867	Integrase core domain; Region: rve_3; pfam13683
714313003868	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
714313003869	multiple promoter invertase; Provisional; Region: mpi; PRK13413
714313003870	catalytic residues [active]
714313003871	catalytic nucleophile [active]
714313003872	Presynaptic Site I dimer interface [polypeptide binding]; other site
714313003873	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
714313003874	Synaptic Flat tetramer interface [polypeptide binding]; other site
714313003875	Synaptic Site I dimer interface [polypeptide binding]; other site
714313003876	DNA binding site [nucleotide binding]
714313003877	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
714313003878	DNA-binding interface [nucleotide binding]; DNA binding site
714313003879	Isochorismatase family; Region: Isochorismatase; pfam00857
714313003880	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
714313003881	catalytic triad [active]
714313003882	conserved cis-peptide bond; other site
714313003883	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
714313003884	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
714313003885	active site
714313003886	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
714313003887	nudix motif; other site
714313003888	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
714313003889	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
714313003890	Helix-turn-helix domain; Region: HTH_38; pfam13936
714313003891	Integrase core domain; Region: rve; pfam00665
714313003892	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
714313003893	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
714313003894	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
714313003895	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
714313003896	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
714313003897	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
714313003898	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
714313003899	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09729
714313003900	CRISPR-associated protein Cse2 (CRISPR_cse2); Region: CRISPR_Cse2; pfam09485
714313003901	CT1975-like protein; Region: Cas_CT1975; pfam09344
714313003902	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
714313003903	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09756
714313003904	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
714313003905	Probable transposase; Region: OrfB_IS605; pfam01385
714313003906	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
714313003907	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
714313003908	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003909	Transposase; Region: HTH_Tnp_1; pfam01527
714313003910	putative transposase OrfB; Reviewed; Region: PHA02517
714313003911	HTH-like domain; Region: HTH_21; pfam13276
714313003912	Integrase core domain; Region: rve; pfam00665
714313003913	Integrase core domain; Region: rve_3; pfam13683
714313003914	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
714313003915	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
714313003916	putative NAD(P) binding site [chemical binding]; other site
714313003917	Initiator Replication protein; Region: Rep_3; pfam01051
714313003918	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
714313003919	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
714313003920	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
714313003921	HNH endonuclease; Region: HNH_2; pfam13391
714313003922	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
714313003923	GIY-YIG motif/motif A; other site
714313003924	active site
714313003925	catalytic site [active]
714313003926	metal binding site [ion binding]; metal-binding site
714313003927	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
714313003928	Uncharacterized conserved protein [Function unknown]; Region: COG3410
714313003929	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
714313003930	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
714313003931	Na binding site [ion binding]; other site
714313003932	cytosine deaminase; Provisional; Region: PRK09230
714313003933	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
714313003934	active site
714313003935	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
714313003936	IHF - DNA interface [nucleotide binding]; other site
714313003937	IHF dimer interface [polypeptide binding]; other site
714313003938	potential frameshift: common BLAST hit: gi|330818953|ref|YP_004385932.1| transposase mutator type
714313003939	Transposase, Mutator family; Region: Transposase_mut; pfam00872
714313003940	Transposase, Mutator family; Region: Transposase_mut; pfam00872
714313003941	MULE transposase domain; Region: MULE; pfam10551
714313003942	Protein of unknown function (DUF436); Region: DUF436; pfam04260
714313003943	putative transposase OrfB; Reviewed; Region: PHA02517
714313003944	HTH-like domain; Region: HTH_21; pfam13276
714313003945	Integrase core domain; Region: rve_3; pfam13683
714313003946	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003947	Transposase; Region: HTH_Tnp_1; pfam01527
714313003948	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
714313003949	multiple promoter invertase; Provisional; Region: mpi; PRK13413
714313003950	catalytic residues [active]
714313003951	catalytic nucleophile [active]
714313003952	Presynaptic Site I dimer interface [polypeptide binding]; other site
714313003953	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
714313003954	Synaptic Flat tetramer interface [polypeptide binding]; other site
714313003955	Synaptic Site I dimer interface [polypeptide binding]; other site
714313003956	DNA binding site [nucleotide binding]
714313003957	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003958	Transposase; Region: HTH_Tnp_1; pfam01527
714313003959	HTH-like domain; Region: HTH_21; pfam13276
714313003960	Integrase core domain; Region: rve; pfam00665
714313003961	DDE domain; Region: DDE_Tnp_IS240; pfam13610
714313003962	Integrase core domain; Region: rve_2; pfam13333
714313003963	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
714313003964	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
714313003965	P-loop; other site
714313003966	Magnesium ion binding site [ion binding]; other site
714313003967	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
714313003968	Magnesium ion binding site [ion binding]; other site
714313003969	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
714313003970	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
714313003971	Magnesium ion binding site [ion binding]; other site
714313003972	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
714313003973	HTH-like domain; Region: HTH_21; pfam13276
714313003974	Integrase core domain; Region: rve; pfam00665
714313003975	Integrase core domain; Region: rve_3; cl15866
714313003976	Transposase; Region: HTH_Tnp_1; pfam01527
714313003977	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
714313003978	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
714313003979	active site
714313003980	purine riboside binding site [chemical binding]; other site
714313003981	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
714313003982	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
714313003983	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
714313003984	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
714313003985	active site
714313003986	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
714313003987	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
714313003988	active site
714313003989	DNA binding site [nucleotide binding]
714313003990	Int/Topo IB signature motif; other site
714313003991	HTH-like domain; Region: HTH_21; pfam13276
714313003992	Integrase core domain; Region: rve; pfam00665
714313003993	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
714313003994	Helix-turn-helix domain; Region: HTH_28; pfam13518
714313003995	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
714313003996	non-specific DNA binding site [nucleotide binding]; other site
714313003997	salt bridge; other site
714313003998	sequence-specific DNA binding site [nucleotide binding]; other site
714313003999	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
714313004000	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
714313004001	cofactor binding site; other site
714313004002	DNA binding site [nucleotide binding]
714313004003	substrate interaction site [chemical binding]; other site
714313004004	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737