-- dump date 20140619_120037 -- class Genbank::CDS -- table cds_note -- id note YP_004097290.1 COGs: COG0593 ATPase involved in DNA replication initiation; InterProIPR001957: IPR013317: IPR013159: IPR003593: IPR 018312: IPR020591; KEGG: kra:Krad_0001 chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: replication initiation factor DnaA; ATPase AAA; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA YP_004097291.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: kse:Ksed_00020 DNA polymerase III beta subunit; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: DNA polymerase III subunit beta; TIGRFAM: DNA polymerase III subunit beta; PFAM: DNA polymerase III subunit beta, C-terminal domain; DNA polymerase III subunit beta, N-terminal domain; DNA polymerase III subunit beta, central domain; TIGRFAM: DNA polymerase III subunit beta YP_004097292.1 COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR006115: IPR006114: IPR004849: IPR006183; KEGG: kse:Ksed_00030 6-phosphogluconate dehydrogenase (decarboxylating); PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain-containing protein; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; manually curated; PFAM: 6-phosphogluconate dehydrogenase, C-terminal domain; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating) YP_004097293.1 COGs: COG1195 recombinational DNA repair ATPase (RecF pathway); InterPro IPR003395: IPR001238: IPR018078; KEGG: kse:Ksed_00040 DNA replication and repair protein RecF; PFAM: SMC domain protein; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA replication and repair protein RecF; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein YP_004097294.1 COGs: COG5512 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives; InterPro IPR007922; KEGG: kra:Krad_0005 protein of unknown function DUF721; PFAM: protein of unknown function DUF721; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF721) YP_004097295.1 COGs: COG3227 Zinc metalloprotease (elastase); InterPro IPR013856: IPR001570; KEGG: cms:CMS_1343 metalloprotease; PFAM: peptidase M4 thermolysin; peptidase M4 thermolysin; SPTR: metalloprotease; PFAM: Thermolysin metallopeptidase, alpha-helical domain; Thermolysin metallopeptidase, catalytic domain YP_004097296.1 KEGG: ske:Sked_09010 hypothetical protein; SPTR: uncharacterized protein YP_004097297.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014325: IPR014284; KEGG: nca:Noca_3654 sigma-70, region 4 type 2; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: Sigma-70, region 4 type 2; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_004097298.1 COGs: COG0187 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR003594: IPR013506: IPR006171: IPR002288: IPR 011557: IPR001241: IPR018522: IPR000565; KEGG: kse:Ksed_00060 DNA gyrase subunit B; PFAM: DNA topoisomerase type IIsubunit alpha B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase B subunit; PFAM: Toprim domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase B subunit YP_004097299.1 COGs: COG0188 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) subunit alpha; InterPro IPR002205: IPR006691: IPR005743; KEGG: kse:Ksed_00070 DNA gyrase subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: DNA gyrase subunit A; TIGRFAM: DNA gyrase subunit alpha; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase subunit alpha YP_004097300.1 KEGG: kra:Krad_0008 hypothetical protein; SPTR: integral membrane protein; PFAM: transmembrane domain of unknown function (DUF3566) YP_004097301.1 KEGG: rsa:RSal33209_0010 hypothetical protein; SPTR: uncharacterized protein YP_004097302.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: fra:Francci3_4274 phage integrase; PFAM: integrase; SPTR: integrase; PFAM: Phage integrase family YP_004097303.1 InterPro IPR010093; KEGG: saq:Sare_1579 DNA binding domain-containing protein; SPTR: DNA binding domain, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family YP_004097304.1 KEGG: fre:Franean1_5522 replication initiator protein; SPTR: Replication initiator protein YP_004097305.1 InterPro IPR003482; KEGG: kra:Krad_4662 transcriptional regulatory protein WhiB-like WhiB2; PFAM: transcription factor WhiB; SPTR: Regulatory protein; PFAM: transcription factor WhiB YP_004097306.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543: IPR003593: IPR000408; KEGG: fra:Francci3_4272 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; SMART: ATPase AAA; SPTR: cell divisionFtsK/SpoIIIE; PFAM: FtsK/SpoIIIE family YP_004097307.1 SPTR: uncharacterized protein YP_004097308.1 KEGG: bta:508547 phosphodiesterase 4D interacting protein; SPTR: PDE4DIP protein YP_004097309.1 KEGG: mmi:MMAR_4843 hypothetical protein; SPTR: uncharacterized protein YP_004097310.1 KEGG: ank:AnaeK_1746 hypothetical protein; SPTR: uncharacterized protein YP_004097311.1 KEGG: tbr:Tb11.02.3740 receptor-type adenylate cyclase GRESAG 4; SPTR: Receptor-type adenylate cyclase GRESAG 4 YP_004097312.1 InterPro IPR011701; KEGG: sro:Sros_4222 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: antibiotic transporter; PFAM: Bacterial protein of unknown function (DUF894) YP_004097313.1 InterPro IPR007278; KEGG: tbi:Tbis_0235 hypothetical protein; PFAM: protein of unknown function DUF397; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF397) YP_004097314.1 InterPro IPR001387; KEGG: fre:Franean1_0907 helix-turn-helix domain-containing protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix YP_004097315.1 KEGG: sna:Snas_0838 hypothetical protein; SPTR: uncharacterized protein YP_004097316.1 COGs: COG0791 cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: sco:SCO3511 lipoprotein; PFAM: NLP/P60 protein; SPTR: NLP/P60 protein; PFAM: NlpC/P60 family YP_004097317.1 KEGG: amd:AMED_1188 hypothetical protein; SPTR: uncharacterized protein YP_004097318.1 KEGG: saq:Sare_4736 hypothetical protein; SPTR: uncharacterized protein YP_004097319.1 KEGG: sen:SACE_1595 hypothetical protein; SPTR: uncharacterized protein YP_004097320.1 KEGG: ami:Amir_0885 hypothetical protein; SPTR: uncharacterized protein YP_004097321.1 KEGG: ami:Amir_0884 hypothetical protein; SPTR: uncharacterized protein YP_004097322.1 InterPro IPR003346; KEGG: mgi:Mflv_1197 transposase, IS111A/IS1328/IS1533; PFAM: transposase IS116/IS110/IS902 family protein; SPTR: transposase, IS111A/IS1328/IS1533; PFAM: transposase IS116/IS110/IS902 family; transposase YP_004097323.1 KEGG: tgo:TGME49_020220 hypothetical protein; SPTR: uncharacterized protein YP_004097324.1 InterPro IPR002514: IPR001523: IPR001584; KEGG: nml:Namu_1602 integrase catalytic region; PFAM: Integrase catalytic region; transposase IS3/IS911 family protein; paired box domain protein; SPTR: Integrase catalytic region; manually curated; PFAM: Integrase core domain; transposase YP_004097325.1 COGs: COG4268 McrBC 5-methylcytosine restriction system component; InterPro IPR019292; KEGG: nth:Nther_0806 McrBC 5-methylcytosine restriction system component-like protein; PFAM: 5-methylcytosine restriction system component-like protein; SPTR: McrBC 5-methylcytosine restriction system component-like protein; PFAM: McrBC 5-methylcytosine restriction system component YP_004097326.1 COGs: COG1401 GTPase subunit of restriction endonuclease; InterPro IPR011704: IPR003593; KEGG: cfl:Cfla_3299 ATPase associated with various cellular activities AAA_5; PFAM: ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; SPTR: ATPase associated with various cellular activities AAA_5; manually curated; PFAM: AAA domain (dynein-related subfamily) YP_004097327.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941: IPR002052: IPR001091; KEGG: bph:Bphy_3423 DNA methylase N-4/N-6 domain-containing protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase YP_004097328.1 KEGG: bph:Bphy_3423 DNA methylase N-4/N-6 domain-containing protein; SPTR: DNA methylase N-4/N-6 domain protein YP_004097329.1 InterPro IPR004919; KEGG: ote:Oter_2248 hypothetical protein; PFAM: protein of unknown function DUF262; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF262 YP_004097330.1 KEGG: npu:Npun_R0144 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004097331.1 InterPro IPR001387; KEGG: rce:RC1_3111 DNA-binding protein, PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein, ; PFAM: Helix-turn-helix YP_004097332.1 COGs: COG3550 conserved hypothetical protein; InterPro IPR012894: IPR012893: IPR017508; KEGG: mva:Mvan_1137 HipA domain-containing protein; PFAM: HipA domain protein; SPTR: HipA domain protein; TIGRFAM: HipA N-terminal domain protein; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain; TIGRFAM: HipA N-terminal domain YP_004097333.1 COGs: COG0515 serine/threonine protein kinase; InterPro IPR017442: IPR002290: IPR000719; KEGG: kra:Krad_3232 protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; SPTR: Probable serine/threonine-protein kinase; PFAM: protein kinase domain YP_004097334.1 COGs: COG2259 membrane protein; InterPro IPR011637; KEGG: kfl:Kfla_3391 DoxX family protein; PFAM: DoxX family protein; SPTR: DoxX family protein; PFAM: DoxX YP_004097335.1 KEGG: nca:Noca_1866 hypothetical protein; SPTR: uncharacterized protein YP_004097336.1 InterPro IPR012312; KEGG: nca:Noca_3980 hemerythrin HHE cation binding domain-containing protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin HHE cation binding domain protein YP_004097337.1 COGs: COG3004 Na+/H+ antiporter; InterPro IPR004670: IPR001853: IPR017936; KEGG: nca:Noca_1867 Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter NhaA; DSBA oxidoreductase; SPTR: Na(+)/H(+) antiporter nhaA 2; TIGRFAM: Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter 1; DSBA-like thioredoxin domain; TIGRFAM: Na+/H+ antiporter NhaA; TC 2.A.33.1.1 YP_004097338.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR012257: IPR017900: IPR017896; KEGG: gob:Gobs_0251 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: uncharacterized protein; PFAM: Cysteine-rich domain YP_004097339.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: sen:SACE_4261 (S)-2-hydroxy-acid oxidase subunit D; PFAM: FAD linked oxidase; SPTR: (S)-2-hydroxy-acid oxidase subunit D; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase subunit GlcD YP_004097340.1 COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: nml:Namu_3729 L-lactate transport; PFAM: L-lactate permease; SPTR: L-lactate transport; TIGRFAM: L-lactate transport; PFAM: L-lactate permease; TIGRFAM: L-lactate transport YP_004097341.1 COGs: COG2186 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sen:SACE_3508 GntR family transcriptional regulator; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004097342.1 InterPro IPR011600: IPR018247; KEGG: amd:AMED_1757 caspase-related protein; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: uncharacterized protein; PFAM: Caspase domain YP_004097343.1 KEGG: amd:AMED_1504 hypothetical protein; SPTR: uncharacterized protein YP_004097344.1 InterPro IPR018247; KEGG: bcv:Bcav_0018 mucin-associated surface protein (MASP); SPTR: uncharacterized protein YP_004097345.1 KEGG: sgr:SGR_1730 hypothetical protein; SPTR: uncharacterized protein YP_004097346.1 COGs: COG0652 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR020892; KEGG: kse:Ksed_00140 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; PRIAM: peptidylprolyl isomerase; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004097347.1 COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: xce:Xcel_0012 rhomboid family protein; PFAM: rhomboid family protein; SPTR: rhomboid family protein; PFAM: Rhomboid family YP_004097348.1 InterPro IPR009619; KEGG: bcv:Bcav_0021 protein of unknown function UPF0233; PFAM: protein of unknown function UPF0233; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0233) YP_004097349.1 COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: kra:Krad_0026 protein of unknown function DUF881; PFAM: protein of unknown function DUF881; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF881) YP_004097350.1 COGs: COG0512 anthranilate/para-aminobenzoate synthase component II; InterProIPR000991: IPR006221: IPR006220: IPR011702: IPR 001317: IPR017926; KEGG: xce:Xcel_0017 glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; SPTR: Para-aminobenzoate synthase component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004097351.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR020635: IPR002290: IPR 017441: IPR008271: IPR000719; KEGG: kra:Krad_0072 protein kinase; PFAM: serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Tyrosine protein kinase:serine/threonine protein kinase:PASTA; PFAM: protein kinase domain; PASTA domain YP_004097352.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR017442: IPR020635: IPR002290: IPR008271: IPR 000719; KEGG: nca:Noca_0023 protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: protein kinase; PFAM: protein kinase domain YP_004097353.1 COGs: COG0768 cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: kse:Ksed_00200 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: PbpA; PFAM: Penicillin binding protein transpeptidase domain YP_004097354.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: kra:Krad_0074 cell cycle protein; PFAM: cell cycle protein; SPTR: FtsW/RodA/SpoVE family cell cycle protein; PFAM: cell cycle protein YP_004097355.1 COGs: COG0631 serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: kra:Krad_0075 protein phosphatase 2C-like; PFAM: protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: magnesium or manganese-dependent protein phosphatase; PFAM: protein phosphatase 2C YP_004097356.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: sco:SCO3844 secreted protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: membrane protein; PFAM: FHA domain YP_004097357.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: kra:Krad_0077 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2662); FHA domain YP_004097358.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: bfa:Bfae_03240 chromosome partitioning ATPase; SPTR: ATPase involved in chromosome partitioning; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004097359.1 COGs: COG2802 Uncharacterized protein similar to the N-terminal domain of Lon protease; InterPro IPR003111; KEGG: kra:Krad_3182 peptidase S16; PFAM: peptidase S16; SMART: peptidase S16; SPTR: peptidase S16; PFAM: ATP-dependent protease La (LON) domain YP_004097360.1 KEGG: bcv:Bcav_3859 hypothetical protein; SPTR: uncharacterized protein YP_004097361.1 COGs: COG2267 lysophospholipase; InterPro IPR000073; KEGG: chy:CHY_0890 alpha/beta fold family hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: lysophospholipase L2; PFAM: lysophospholipase YP_004097362.1 COGs: COG1609 transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: sro:Sros_7934 LacI-family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI-family transcriptional regulator; manually curated; PFAM: Bacterial regulatory proteins, lacI family; family YP_004097363.1 COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: pak:HMPREF0675_5030 bacterial extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004097364.1 COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: pac:PPA1965 binding-protein-dependent transport permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transport permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097365.1 COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: pak:HMPREF0675_5028 ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transport permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097366.1 KEGG: amd:AMED_3009 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF664) YP_004097367.1 InterPro IPR003675: IPR015837; KEGG: sna:Snas_2427 abortive infection protein; PFAM: hypothetical protein; SPTR: Abortive infection protein; PFAM: CAAX amino terminal protease family YP_004097368.1 KEGG: rop:ROP_36620 hypothetical protein; SPTR: uncharacterized protein YP_004097369.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: art:Arth_2897 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: carbohydrate kinase; PFAM: pfkB family carbohydrate kinase YP_004097370.1 COGs: COG2951 membrane-bound lytic murein transglycosylase B; KEGG: sgr:SGR_1028 hypothetical protein; SPTR: lytic transglycosylase catalytic YP_004097371.1 COGs: COG0155 Sulfite reductase subunit beta (hemoprotein); InterPro IPR005117: IPR006067: IPR006066; KEGG: xce:Xcel_0718 sulfite reductase (ferredoxin); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Sulfite reductase (ferredoxin); SPTR: Sulfite reductase (Ferredoxin); PFAM: nitrite and sulphite reductase 4Fe-4S domain; nitrite/Sulfite reductase ferredoxin-like half domain YP_004097372.1 COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500: IPR004511; KEGG: jde:Jden_0661 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: 3'-phosphoadenosine 5'-phosphosulfate reductase; TIGRFAM: phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase family; TIGRFAM: phosophoadenylyl-sulfate reductase (thioredoxin) YP_004097373.1 COGs: COG0007 uroporphyrinogen-III methylase; InterPro IPR000878: IPR006367: IPR006366; KEGG: aau:AAur_3076 uroporphyrin-III C-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase, N-terminal domain YP_004097374.1 COGs: COG0510 choline kinase involved in LPS biosynthesis; InterPro IPR002575; KEGG: scb:SCAB_38761 phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: phosphotransferase; PFAM: phosphotransferase enzyme family YP_004097375.1 InterPro IPR006311; KEGG: scb:SCAB_25881 integral membrane protein; SPTR: IucA/IucC family protein YP_004097376.1 KEGG: cai:Caci_5577 von Willebrand factor A; SPTR: Gp207 YP_004097377.1 KEGG: fre:Franean1_6437 hypothetical protein; SPTR: uncharacterized protein YP_004097378.1 InterPro IPR018764; KEGG: nca:Noca_4536 hypothetical protein; PFAM: anti-sigma K factor RskA; SPTR: uncharacterized protein; PFAM: anti-sigma-K factor rskA YP_004097379.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: nca:Noca_4535 RNA polymerase sigma factor SigK; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004097380.1 COGs: COG2335 Secreted and surface protein containing fasciclin-like repeats; InterPro IPR000782: IPR017909; KEGG: nca:Noca_4534 beta-Ig-H3/fasciclin; PFAM: beta-Ig-H3/fasciclin; SMART: beta-Ig-H3/fasciclin; SPTR: beta-Ig-H3/fasciclin; PFAM: Fasciclin domain YP_004097381.1 COGs: COG2041 Sulfite oxidase; InterPro IPR000572: IPR005066: IPR006311; KEGG: nca:Noca_4533 oxidoreductase, molybdopterin binding; PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; SPTR: oxidoreductase, molybdopterin binding; PFAM: Mo-co oxidoreductase dimerisation domain; oxidoreductase molybdopterin binding domain YP_004097382.1 KEGG: sco:SCO6177 hypothetical protein; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport YP_004097383.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073: IPR000639; KEGG: nml:Namu_1402 alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold YP_004097384.1 COGs: COG3795 conserved hypothetical protein; InterPro IPR005545; KEGG: amd:AMED_2012 hypothetical protein; PFAM: YCII-related; SPTR: YCII-related protein; PFAM: YCII-related domain YP_004097385.1 COGs: COG0439 Biotin carboxylase; InterPro IPR003135: IPR011761; KEGG: gau:GAU_1512 hypothetical protein; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; SPTR: uncharacterized protein; PFAM: carbamoyl-phosphate synthase L chain, ATP binding domain YP_004097386.1 KEGG: rle:pRL90043 transmembrane transporter; SPTR: transmembrane transporter; manually curated; PFAM: peptidase family S51 YP_004097387.1 COGs: COG2382 Enterochelin esterase; InterPro IPR000801; KEGG: ppd:Ppro_1478 esterase; PFAM: esterase; SPTR: esterase; PFAM: Domain of unknown function (DUF3327); esterase YP_004097388.1 COGs: COG4947 conserved hypothetical protein; KEGG: dfe:Dfer_4768 hypothetical protein; SPTR: uncharacterized protein YP_004097389.1 COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: sro:Sros_5772 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004097390.1 COGs: COG2068 Uncharacterized MobA-related protein; KEGG: nca:Noca_3976 hypothetical protein; SPTR: uncharacterized protein YP_004097391.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR003959: IPR003593; KEGG: nca:Noca_3975 ATPase; PFAM: ATPase AAA central domain protein; SMART: ATPase AAA; SPTR: ATPase; PFAM: ATPase family associated with various cellular activities (AAA) YP_004097392.1 COGs: COG3552 protein containing von Willebrand factor A (vWA) domain; InterPro IPR008912: IPR011195: IPR002035: IPR005829; KEGG: nca:Noca_3974 VWA containing CoxE family protein; PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor A; SPTR: VWA containing CoxE family protein; PFAM: VWA domain containing CoxE-like protein YP_004097393.1 COGs: COG1975 xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR003777; KEGG: nca:Noca_3973 hypothetical protein; PFAM: protein of unknown function DUF182; SPTR: uncharacterized protein; PFAM: XdhC and CoxI family YP_004097394.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; KEGG: cwo:Cwoe_4749 NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family YP_004097395.1 InterPro IPR003615; KEGG: art:Arth_1274 HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease YP_004097396.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: kfl:Kfla_0935 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family YP_004097397.1 InterPro IPR011701; KEGG: kfl:Kfla_6439 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Bacterial protein of unknown function (DUF894) YP_004097398.1 InterPro IPR001845; KEGG: aau:AAur_3335 hypothetical protein; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory protein, arsR family YP_004097399.1 COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041: IPR002888; KEGG: gob:Gobs_4925 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding domain-containing protein; ferredoxin; SPTR: Hypothetical dehydrogenase; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain YP_004097400.1 COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674: IPR008274; KEGG: nca:Noca_3969 xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: Nicotine dehydrogenase chain C; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: carbon-monoxide dehydrogenase, large subunit YP_004097401.1 COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346: IPR005107: IPR016166; KEGG: nca:Noca_3968 carbon monoxide dehydrogenase, medium subunit; PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; SPTR: Molybdopterin dehydrogenase; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain YP_004097402.1 COGs: COG3427 conserved hypothetical protein; InterPro IPR010419; KEGG: nca:Noca_3967 carbon monoxide dehydrogenase subunit G; PFAM: carbon monoxide dehydrogenase subunit G; SPTR: uncharacterized protein; PFAM: carbon monoxide dehydrogenase subunit G (CoxG) YP_004097403.1 COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: krh:KRH_11610 ornithine cyclodeaminase/mu-crystallin family protein; PFAM: ornithine cyclodeaminase/mu-crystallin; SPTR: ornithine cyclodeaminase/mu-crystallin family protein; PFAM: ornithine cyclodeaminase/mu-crystallin family YP_004097404.1 KEGG: nml:Namu_2334 cyclase/dehyrase; SPTR: cyclase/dehyrase YP_004097405.1 InterPro IPR005754; KEGG: nml:Namu_4659 peptidase C60 sortase A and B; PFAM: peptidase C60 sortase A and B; SPTR: peptidase C60 sortase A and B; PFAM: Sortase family YP_004097406.1 KEGG: btk:BT9727_0885 proline-threonine-rich repeat-containing protein; SPTR: uncharacterized protein YP_004097407.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701: IPR005829; KEGG: gob:Gobs_1377 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Sugar (and other) transporter YP_004097408.1 InterPro IPR012312; KEGG: nml:Namu_3671 hemerythrin HHE cation binding domain protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin HHE cation binding domain protein; PFAM: hemerythrin HHE cation binding domain YP_004097409.1 COGs: COG4309 conserved hypothetical protein; KEGG: pak:HMPREF0675_3286 hypothetical protein; SPTR: Conserved protein; PFAM: Uncharacterized conserved protein (DUF2249) YP_004097410.1 COGs: COG2345 transcriptional regulator protein; KEGG: mgi:Mflv_3487 transcriptional regulator; SPTR: transcriptional regulator YP_004097411.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110: IPR001453: IPR005111: IPR020817; KEGG: bcv:Bcav_1229 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain YP_004097412.1 InterPro IPR005545; KEGG: cfl:Cfla_1953 YCII-related protein; PFAM: YCII-related; SPTR: uncharacterized protein; PFAM: YCII-related domain YP_004097413.1 COGs: COG1526 Uncharacterized protein required for formate dehydrogenase activity; InterPro IPR003786; KEGG: msm:MSMEG_0165 formate dehydrogenase accessory protein; PFAM: formate dehydrogenase subunit FdhD; SPTR: formate dehydrogenase family accessory protein FdhD; PFAM: FdhD/NarQ family; TIGRFAM: formate dehydrogenase family accessory protein FdhD YP_004097414.1 COGs: COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: nml:Namu_2297 molybdopterin-guanine dinucleotide biosynthesis protein A; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein A YP_004097415.1 KEGG: kfl:Kfla_5608 hypothetical protein; SPTR: uncharacterized protein YP_004097416.1 COGs: COG0768 cell division protein FtsI/penicillin-binding protein 2; InterPro IPR007887: IPR001460: IPR002137; KEGG: nca:Noca_4600 penicillin-binding protein, transpeptidase; PFAM: penicillin-binding protein transpeptidase; NTF2 domain protein transpeptidase; SPTR: Penicillin-binding protein, transpeptidase; PFAM: Penicillin binding protein transpeptidase domain; NTF2-like N-terminal transpeptidase domain; Penicillin-binding protein dimerisation domain YP_004097417.1 COGs: COG4850 conserved hypothetical protein; InterPro IPR019236; KEGG: kfl:Kfla_5428 hypothetical protein; PFAM: protein of unknown function DUF2183; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2183) YP_004097418.1 COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterPro IPR012319: IPR015886: IPR000214; KEGG: sna:Snas_1400 DNA-formamidopyrimidine glycosylase; PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg) YP_004097419.1 COGs: COG2240 pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749: IPR004625; KEGG: nca:Noca_4006 pyridoxamine kinase; PFAM: phosphomethylpyrimidine kinase type-1; PRIAM: pyridoxal kinase; SPTR: pyridoxal kinase; TIGRFAM: pyridoxal kinase; PFAM: phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase YP_004097420.1 InterPro IPR005829: IPR009056; KEGG: kse:Ksed_01160 hypothetical protein; SPTR: uncharacterized protein YP_004097421.1 InterPro IPR001607; KEGG: rop:ROP_38800 hypothetical protein; SPTR: Zinc finger domain protein; PFAM: Zn-finger in ubiquitin-hydrolases and other protein YP_004097422.1 KEGG: bfa:Bfae_28560 hypothetical protein; SPTR: uncharacterized protein YP_004097423.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: ace:Acel_0379 ECF subfamily RNA polymerase sigma-24 factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004097424.1 KEGG: art:Arth_3793 protein tyrosine phosphatase, receptor type, F -like protein; SPTR: protein tyrosine phosphatase, receptor type, F (Predicted)-like protein YP_004097425.1 COGs: COG4770 acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 000022: IPR011761: IPR011764: IPR011763; KEGG: kfl:Kfla_3307 carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carboxyl transferase; SPTR: carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: carboxyl transferase domain; carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; acetyl-CoA carboxylase, central region; carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme YP_004097426.1 KEGG: pan:PODANSg8735 hypothetical protein; SPTR: Predicted CDS Pa_2_8850 YP_004097427.1 COGs: COG1522 transcriptional regulators; InterPro IPR019887: IPR019888: IPR000485; KEGG: nca:Noca_1625 AsnC family transcriptional regulator; PFAM: transcription regulator AsnC-type-like; SMART: transcription regulator AsnC-type; SPTR: transcriptional regulator, AsnC family; PFAM: AsnC family YP_004097428.1 COGs: COG4309 conserved hypothetical protein; KEGG: nca:Noca_2100 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2249) YP_004097429.1 COGs: COG3033 tryptophanase; InterPro IPR001597: IPR011166; KEGG: nca:Noca_1624 tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: tryptophanase; SPTR: tryptophanase; PFAM: beta-eliminating lyase YP_004097430.1 COGs: COG3033 tryptophanase; InterPro IPR001597: IPR011166: IPR013441; KEGG: sth:STH2842 tyrosine phenol-lyase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Tyrosine phenol-lyase; SPTR: Tyrosine phenol-lyase; TIGRFAM: tyrosine phenol-lyase; PFAM: beta-eliminating lyase; TIGRFAM: tyrosine phenol-lyase YP_004097431.1 COGs: COG3899 ATPase; InterPro IPR000792; KEGG: nca:Noca_4382 regulatory protein, LuxR; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: LuxR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family YP_004097432.1 KEGG: nve:NEMVE_v1g242007 hypothetical protein; SPTR: Predicted protein YP_004097433.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR009081; KEGG: saq:Sare_1889 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: phosphopantetheine attachment site; AMP-binding enzyme YP_004097434.1 COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR004307; KEGG: krh:KRH_21230 hypothetical protein; PFAM: TspO/MBR family protein; NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: TspO/MBR family; NmrA-like family YP_004097435.1 InterPro IPR003675; KEGG: kse:Ksed_01050 CAAX amino terminal protease family; PFAM: hypothetical protein; SPTR: Probable integral membrane protein; PFAM: CAAX amino terminal protease family YP_004097436.1 COGs: COG0415 deoxyribodipyrimidine photolyase; InterProIPR006050: IPR005101: IPR001969: IPR018394: IPR 002081; KEGG: kra:Krad_3554 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; PRIAM: deoxyribodipyrimidine photo-lyase; SPTR: Phr; PFAM: FAD binding domain of DNA photolyase; DNA photolyase YP_004097437.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198: IPR002347; KEGG: avi:Avi_0085 gluconate 5-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004097438.1 COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR003333; KEGG: sen:SACE_6753 cyclopropane-fatty-acyl-phospholipid synthase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; PRIAM: Cyclopropane-fatty-acyl-phospholipid synthase; SPTR: Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (Cyclopropane fatty acid synthase) (CFA synthase); PFAM: Cyclopropane-fatty-acyl-phospholipid synthase YP_004097439.1 COGs: COG3496 conserved hypothetical protein; InterPro IPR010775; KEGG: rer:RER_23220 hypothetical protein; PFAM: protein of unknown function DUF1365; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1365) YP_004097440.1 COGs: COG2907 NAD/FAD-binding protein; InterPro IPR002937; KEGG: sgr:SGR_5877 amine oxidoreductase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase YP_004097441.1 InterPro IPR019587; KEGG: art:Arth_3265 hypothetical protein; PFAM: polyketide cyclase/dehydrase; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport YP_004097442.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551: IPR006158; KEGG: msv:Mesil_1484 transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Probable transcriptional regulator; PFAM: MerR family regulatory protein; B12 binding domain YP_004097443.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: art:Arth_0341 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase; manually curated; PFAM: polysaccharide deacetylase YP_004097444.1 COGs: COG0659 sulfate permease and related transporter (MFS superfamily); InterPro IPR011547: IPR002645: IPR001902; KEGG: cef:CE1093 sulfate transporter; PFAM: sulfate transporter; sulfate transporter/antisigma-factor antagonist STAS; SPTR: sulfate transport protein; TIGRFAM: sulfate transporter; PFAM: sulfate transporter family; STAS domain; TIGRFAM: high affinity sulfate transporter 1 YP_004097445.1 COGs: COG1270 Cobalamin biosynthesis protein CobD/CbiB; InterPro IPR004485; KEGG: nml:Namu_0174 cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; SPTR: Cobalamin biosynthesis protein CobD; TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD YP_004097446.1 COGs: COG1806 conserved hypothetical protein; InterPro IPR005177; KEGG: gob:Gobs_2870 protein of unknown function DUF299; PFAM: protein of unknown function DUF299; SPTR: phosphotransferase JNB_14093; PFAM: Domain of unknown function (DUF299) YP_004097447.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR002192: IPR008279: IPR000121: IPR006319: IPR 018274; KEGG: gob:Gobs_2869 phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: pyruvate, water dikinase; SPTR: phosphoenolpyruvate synthase; TIGRFAM: phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: phosphoenolpyruvate synthase YP_004097448.1 InterPro IPR002941: IPR017985: IPR001091; KEGG: cur:cur_0372 hypothetical protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: uncharacterized protein; PFAM: DNA methylase YP_004097449.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: dds:Ddes_2090 rhodanese domain protein; PFAM: rhodanese; SMART: rhodanese; SPTR: thiosulfate sulfurtransferase; PFAM: Rhodanese-like domain YP_004097450.1 InterPro IPR006640; KEGG: nca:Noca_3805 protein of unknown function SprT; SMART: protein of unknown function SprT; SPTR: uncharacterized protein; PFAM: SprT-like family YP_004097451.1 COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000878: IPR000182; KEGG: tbi:Tbis_1840 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family; Tetrapyrrole (Corrin/Porphyrin) methylases YP_004097452.1 COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: cfl:Cfla_0709 sodium:neurotransmitter symporter; PFAM: sodium:neurotransmitter symporter; SPTR: transporter; PFAM: Sodium:neurotransmitter symporter family YP_004097453.1 KEGG: krh:KRH_05460 hypothetical protein; SPTR: uncharacterized protein YP_004097454.1 COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: nca:Noca_4612 PadR family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: PadR family transcriptional regulator; PFAM: transcriptional regulator PadR-like family YP_004097455.1 InterPro IPR003594; KEGG: tcu:Tcur_0095 anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: regulatory protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004097456.1 KEGG: kse:Ksed_01600 hypothetical protein; SPTR: uncharacterized protein YP_004097457.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: kra:Krad_0170 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase family 2; PFAM: glycosyl transferase family 2 YP_004097458.1 KEGG: tcu:Tcur_0118 hypothetical protein; SPTR: uncharacterized protein YP_004097459.1 KEGG: ace:Acel_2106 hypothetical protein; SPTR: uncharacterized protein YP_004097460.1 COGs: COG0077 prephenate dehydratase; InterPro IPR001086: IPR002912: IPR018528; KEGG: ach:Achl_0282 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; SPTR: prephenate dehydratase; PFAM: prephenate dehydratase YP_004097461.1 KEGG: ade:Adeh_4153 outer membrane efflux protein; SPTR: Outer membrane efflux protein YP_004097462.1 COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: mbt:JTY_0076 hypothetical protein; PFAM: amidohydrolase; SPTR: uncharacterized protein Mb0076; PFAM: Amidohydrolase family YP_004097463.1 COGs: COG0672 High-affinity Fe2+/Pb2+ permease; InterPro IPR004923; KEGG: amd:AMED_8204 high-affinity iron transporter; PFAM: iron permease FTR1; SPTR: membrane protein; PFAM: Iron permease FTR1 family; TIGRFAM: FTR1 family protein YP_004097464.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: xce:Xcel_3229 diacylglycerol kinase; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase; SPTR: uncharacterized protein; PFAM: diacylglycerol kinase catalytic domain YP_004097465.1 KEGG: xce:Xcel_3194 hypothetical protein; SPTR: uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain YP_004097466.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: cfl:Cfla_0574 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: oxidoreductase domain protein; PFAM: oxidoreductase family, NAD-binding Rossmann fold YP_004097467.1 COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646; KEGG: kfl:Kfla_5660 pentapeptide repeat protein; PFAM: pentapeptide repeat protein; SPTR: Pentapeptide repeat protein; PFAM: protein of unknown function (DUF664); Pentapeptide repeats (8 copies) YP_004097468.1 COGs: COG0364 glucose-6-phosphate 1-dehydrogenase; InterPro IPR001282: IPR019796; KEGG: mjl:Mjls_5357 glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase; PRIAM: glucose-6-phosphate dehydrogenase; SPTR: glucose-6-phosphate 1-dehydrogenase; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase, C-terminal domain; glucose-6-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase YP_004097469.1 InterPro IPR005135; KEGG: bcv:Bcav_1530 endonuclease/exonuclease/phosphatase; PFAM: endonuclease/exonuclease/phosphatase; SPTR: Phytase YP_004097470.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: nca:Noca_4497 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter YP_004097471.1 KEGG: xce:Xcel_0762 hypothetical protein; SPTR: uncharacterized protein YP_004097472.1 COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR003439: IPR005876: IPR003593: IPR017871; KEGG: sro:Sros_0995 cobalt ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: Cobalt ABC transporter ATPase; TIGRFAM: cobalt ABC transporter ATPase; PFAM: ABC transporter; TIGRFAM: cobalt transporter ATP-binding subunit YP_004097473.1 COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339: IPR012809; KEGG: nca:Noca_1329 cobalt ABC transporter inner membrane subunit CbiQ; PFAM: cobalt transporter; SPTR: Cobalt ABC transporter inner membrane subunit CbiQ; TIGRFAM: cobalt ABC transporter inner membrane subunit CbiQ; PFAM: Cobalt transporter; TIGRFAM: cobalt ABC transporter permease CbiQ YP_004097474.1 KEGG: ncr:NCU01878 hypothetical protein; SPTR: Predicted protein YP_004097475.1 COGs: COG0172 Seryl-tRNA synthetase; InterProIPR015866: IPR002314: IPR002317: IPR018156: IPR 006195; KEGG: kra:Krad_0249 seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like; PRIAM: serine--tRNA ligase; SPTR: Seryl-tRNA synthetase; TIGRFAM: seryl-tRNA synthetase; PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase YP_004097476.1 COGs: COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR001327: IPR004099: IPR013027: IPR000815; KEGG: sco:SCO3443 pyridine nucleotide-disulphide oxidoreductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004097477.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: kfl:Kfla_1685 myo-inosose-2 dehydratase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: myo-inosose-2 dehydratase; SPTR: myo-inositol catabolism protein; PFAM: Xylose isomerase-like TIM barrel YP_004097478.1 KEGG: ami:Amir_2064 superoxide dismutase; SPTR: superoxide dismutase; manually curated YP_004097479.1 KEGG: kfl:Kfla_6838 hypothetical protein; SPTR: uncharacterized protein YP_004097480.1 KEGG: det:DET0762 hypothetical protein; SPTR: uncharacterized protein YP_004097481.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200: IPR006379: IPR000150; KEGG: cfl:Cfla_3183 HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; SPTR: Hydrolase (HAD superfamily protein); TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004097482.1 COGs: COG3795 conserved hypothetical protein; InterPro IPR005545; KEGG: pfo:Pfl01_2519 DGPFAETKE; PFAM: YCII-related; SPTR: Conserved DGPFAETKE domain protein; PFAM: YCII-related domain YP_004097483.1 COGs: COG4941 RNA polymerase sigma factor containing a TPR repeat domain; InterPro IPR007627: IPR013249: IPR014284; KEGG: cwo:Cwoe_0348 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004097484.1 KEGG: bja:blr0248 hypothetical protein; SPTR: uncharacterized protein; PFAM: uracil DNA glycosylase superfamily YP_004097485.1 COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: bja:blr0249 hypothetical protein; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family YP_004097486.1 COGs: COG1335 amidase related to nicotinamidase; InterPro IPR000868; KEGG: sna:Snas_0489 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family YP_004097487.1 COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537; KEGG: kse:Ksed_01710 rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: rRNA methylase; PFAM: SpoU rRNA methylase family YP_004097488.1 KEGG: kse:Ksed_01720 hypothetical protein; SPTR: uncharacterized protein YP_004097489.1 COGs: COG2217 Cation transport ATPase; InterPro IPR005834; KEGG: mmi:MMAR_0231 cation transporter p-type ATPase CtpA_1; PFAM: haloacid dehalogenase; SPTR: Cation-transporting P-type ATPase; PFAM: haloacid dehalogenase-like hydrolase YP_004097490.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: kfl:Kfla_1527 protein of unknown function DUF156; PFAM: protein of unknown function DUF156; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1937 YP_004097491.1 InterPro IPR006121: IPR017969: IPR000428; KEGG: amd:AMED_3508 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: metal-binding protein; PFAM: Heavy-metal-associated domain YP_004097492.1 KEGG: sro:Sros_0019 hypothetical protein; SPTR: uncharacterized protein YP_004097493.1 COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR008250: IPR005834: IPR006403: IPR 006416: IPR001757: IPR018303: IPR017969: IPR000150: IPR000695; KEGG: rop:ROP_pROB01-02380 copper-transporting ATPase CopA; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: copper-transporting ATPase CopA; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase P; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; ATPase P; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004097494.1 COGs: COG0015 adenylosuccinate lyase; InterPro IPR000362: IPR013539: IPR004769: IPR020557; KEGG: kse:Ksed_01820 adenylosuccinate lyase; PFAM: adenylosuccinate lyase domain-containing protein; fumarate lyase; SPTR: adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase YP_004097495.1 COGs: COG3324 protein related to lactoylglutathione lyase; InterPro IPR004360: IPR013838; KEGG: amd:AMED_0924 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase/bleomycin resistance protein/dioxygenase YP_004097496.1 COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867: IPR000106; KEGG: sco:SCO3921 low molecular weight protein-tyrosine-phosphatase; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: protein tyrosine phosphatase; manually curated; PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_004097497.1 KEGG: mlo:mlr0593 hypothetical protein; SPTR: uncharacterized protein YP_004097498.1 InterPro IPR011701; KEGG: cmi:CMM_2049 MFS permease; PFAM: major facilitator superfamily MFS_1; SPTR: MFS permease; PFAM: Bacterial protein of unknown function (DUF894) YP_004097499.1 COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509: IPR005886; KEGG: gbr:Gbro_0593 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase YP_004097500.1 InterPro IPR001915; KEGG: msm:MSMEG_3631 integral membrane protein; PFAM: peptidase M48 Ste24p; SPTR: uncharacterized protein; PFAM: peptidase family M48 YP_004097501.1 COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: kse:Ksed_01860 predicted transcriptional regulator; PFAM: Penicillinase repressor; SPTR: transcriptional regulator-like protein; PFAM: Penicillinase repressor YP_004097502.1 COGs: COG4987 ABC-type transporter involved in cytochrome bd biosynthesis fused ATPase and permeases; InterPro IPR003439: IPR014223: IPR003593: IPR017940; KEGG: kse:Ksed_01870 cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydC; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; TIGRFAM: ABC transporter CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter; TIGRFAM: thiol reductant ABC exporter, CydC subunit YP_004097503.1 COGs: COG4988 ABC-type transporter involved in cytochrome bd biosynthesis ATPase and permeases; InterProIPR001140: IPR003439: IPR014216: IPR003593: IPR 017871: IPR017940; KEGG: kse:Ksed_01870 cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydC; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC transporter; TIGRFAM: ABC transporter CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; PFAM: ABC transporter transmembrane region; ABC transporter; TIGRFAM: thiol reductant ABC exporter, CydD subunit YP_004097504.1 COGs: COG1294 cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: nca:Noca_0943 cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; SPTR: cytochrome d ubiquinol oxidase subunit II; TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase subunit II (cydB) YP_004097505.1 COGs: COG1271 cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: nca:Noca_0942 cytochrome bd ubiquinol oxidase subunit I; PFAM: cytochrome bd ubiquinol oxidase subunit I; SPTR: cytochrome d ubiquinol oxidase subunit I; PFAM: Bacterial cytochrome Ubiquinol Oxidase YP_004097506.1 COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: nfa:nfa49100 transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family YP_004097507.1 COGs: COG0167 dihydroorotate dehydrogenase; InterPro IPR012135: IPR005719: IPR001295; KEGG: nml:Namu_4274 dihydroorotate dehydrogenase 2; PFAM: dihydroorotate oxidase; SPTR: dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2 YP_004097508.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873: IPR011880; KEGG: kfl:Kfla_6851 phenylacetate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate-CoA ligase; TIGRFAM: phenylacetate-CoA ligase; PFAM: AMP-binding enzyme; TIGRFAM: phenylacetate-CoA ligase YP_004097509.1 COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: sma:SAV_2984 arginine/ornithine transport ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: arginine/ornithine ABC transport ATP-binding protein; PFAM: ABC transporter YP_004097510.1 COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515: IPR010065: IPR018062; KEGG: pfr:PFREUD_22920 polar amino acid ABC transporter inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Polar amino acid ABC transporter inner membrane component; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family YP_004097511.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: kra:Krad_1224 extracellular solute-binding protein family 3; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: extracellular solute-binding protein family 3; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004097512.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR014021: IPR 014014; KEGG: nca:Noca_4567 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase; helicase; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004097513.1 COGs: COG1714 membrane protein/domain; InterPro IPR010432; KEGG: gbr:Gbro_4825 RDD domain containing protein; PFAM: RDD domain containing protein; SPTR: Possible conserved membrane protein; PFAM: RDD family YP_004097514.1 COGs: COG1300 membrane protein; InterPro IPR002798; KEGG: nca:Noca_3912 integral membrane protein; PFAM: protein of unknown function DUF95 transmembrane; SPTR: membrane protein; manually curated; PFAM: integral membrane protein DUF95 YP_004097515.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor A (vWA) domain); InterPro IPR002881; KEGG: nca:Noca_3911 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF58 YP_004097516.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR011703: IPR016366: IPR003593; KEGG: gbr:Gbro_4821 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: ATPase AAA; SPTR: regulatory protein; PFAM: ATPase family associated with various cellular activities (AAA) YP_004097517.1 KEGG: nca:Noca_3909 secreted protein; SPTR: Secreted protein YP_004097518.1 KEGG: amd:AMED_1140 hypothetical protein; SPTR: integral membrane protein YP_004097519.1 KEGG: mul:MUL_4272 hypothetical protein; SPTR: integral membrane protein; PFAM: membrane domain of glycerophosphoryl diester phosphodiesterase YP_004097520.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683: IPR003736: IPR011973; KEGG: kfl:Kfla_6849 phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; SPTR: Probable phenylacetic acid degradation protein; TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD YP_004097521.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR006108: IPR006180; KEGG: kse:Ksed_01910 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004097522.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR011975; KEGG: kse:Ksed_01930 phenylacetic acid degradation protein PaaN; PFAM: aldehyde dehydrogenase; SPTR: Phenylacetic acid degradation protein paaN; TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN YP_004097523.1 InterPro IPR011701; KEGG: nca:Noca_2339 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: transporter; PFAM: Major Facilitator Superfamily YP_004097524.1 InterPro IPR007253; KEGG: ace:Acel_1487 cell wall binding repeat 2-containing protein; PFAM: cell wall binding repeat 2-containing protein; SPTR: LytC; PFAM: cell wall binding repeat 2 YP_004097525.1 COGs: COG0419 ATPase involved in DNA repair; KEGG: cfl:Cfla_0124 exonuclease; SPTR: exonuclease; TIGRFAM: exonuclease SbcC YP_004097526.1 COGs: COG0420 DNA repair exonuclease; InterPro IPR004843: IPR004593; KEGG: cmi:CMM_0677 dsDNA exonuclease subunit; PFAM: metallophosphoesterase; SPTR: dsDNA exonuclease subunit; TIGRFAM: nuclease SbcCD, D subunit; manually curated; PFAM: Calcineurin-like phosphoesterase; type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD YP_004097527.1 KEGG: fre:Franean1_6978 hypothetical protein; SPTR: uncharacterized protein YP_004097528.1 KEGG: mav:MAV_2846 hypothetical protein; SPTR: uncharacterized protein; PFAM: TfoX N-terminal domain YP_004097529.1 InterPro IPR007165; KEGG: kse:Ksed_02330 predicted membrane protein; PFAM: membrane protein of unknown function; SPTR: Predicted membrane protein; PFAM: membrane protein of unknown function YP_004097530.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023: IPR012003: IPR012829: IPR015912; KEGG: tbi:Tbis_1326 phosphofructokinase; PFAM: phosphofructokinase; SPTR: phosphofructokinase; TIGRFAM: phosphofructokinase; PFAM: phosphofructokinase; TIGRFAM: phosphofructokinase YP_004097531.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001917; KEGG: sma:SAV_4261 aminotransferase; PFAM: aminotransferase class I and II; SPTR: histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_004097532.1 COGs: COG1071 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit alpha; InterPro IPR001017: IPR017596; KEGG: nca:Noca_4509 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: pyruvate dehydrogenase (acetyl-transferring); SPTR: pyruvate dehydrogenase (acetyl-transferring); TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, subunit alpha; PFAM: dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, subunit alpha YP_004097533.1 COGs: COG0022 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit beta; InterPro IPR005475: IPR005476; KEGG: cai:Caci_0092 transketolase; PFAM: transketolase; transketolase domain-containing protein; SPTR: branched-chain alpha keto acid dehydrogenase E1 subunit beta; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain YP_004097534.1 COGs: COG0508 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089: IPR004167: IPR001078; KEGG: kse:Ksed_02370 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme YP_004097535.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638: IPR005829: IPR001411; KEGG: bfa:Bfae_08840 drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter EmrB/QacA subfamily; TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter EmrB/QacA subfamily YP_004097536.1 InterPro IPR001647; KEGG: fra:Francci3_0716 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family YP_004097537.1 COGs: COG1734 DnaK suppressor protein; InterPro IPR000962; KEGG: bcv:Bcav_3682 TraR/DksA family transcriptional regulator; SPTR: TraR/DksA family transcriptional regulator; PFAM: Prokaryotic dksA/traR C4-type zinc finger YP_004097538.1 KEGG: gob:Gobs_1105 hypothetical protein; SPTR: uncharacterized protein YP_004097539.1 COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; InterPro IPR001046; KEGG: aau:AAur_pTC10168 H(+)-stimulated manganese uptake protein; PFAM: natural resistance-associated macrophage protein; SPTR: Mn2+/Fe2+ transporter NRAMP family; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters YP_004097540.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: mgi:Mflv_5166 Fis family transcriptional regulator; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Fis family transcriptional regulator; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004097541.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006090; KEGG: mgi:Mflv_5167 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain YP_004097542.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753: IPR018376; KEGG: gob:Gobs_3773 enoyl-CoA hydratase/isomerase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase/isomerase; PFAM: enoyl-CoA hydratase/isomerase family YP_004097543.1 InterPro IPR011701; KEGG: sma:SAV_2408 transmembrane efflux protein; PFAM: major facilitator superfamily MFS_1; SPTR: transmembrane efflux protein; PFAM: Major Facilitator Superfamily YP_004097544.1 InterPro IPR003018: IPR005561: IPR012074; KEGG: rop:ROP_10100 hypothetical protein; PFAM: ANTAR domain protein; GAF domain protein; SMART: GAF domain protein; SPTR: uncharacterized protein; PFAM: ANTAR domain YP_004097545.1 InterPro IPR017517; KEGG: tcu:Tcur_3849 hypothetical protein; SPTR: uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: uncharacterized Actinobacterial protein TIGR03083 YP_004097546.1 COGs: COG3336 membrane protein; InterPro IPR019108; KEGG: kse:Ksed_26540 predicted membrane protein; PFAM: cytochrome C oxidase caa3-type, assembly factor CtaG-related; SPTR: uncharacterized protein; PFAM: cytochrome C oxidase caa3 assembly factor (Caa3_CtaG); Copper resistance protein D YP_004097547.1 KEGG: pfr:PFREUD_12670 hypothetical protein; SPTR: uncharacterized protein YP_004097548.1 COGs: COG0388 amidohydrolase; InterPro IPR003010: IPR001110; KEGG: kse:Ksed_26530 predicted amidohydrolase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: hydrolase; PFAM: carbon-nitrogen hydrolase YP_004097549.1 InterPro IPR000866: IPR001258: IPR017936; KEGG: ach:Achl_3716 NHL repeat containing protein; PFAM: NHL repeat containing protein; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; SPTR: NHL repeat containing protein; PFAM: NHL repeat; AhpC/TSA family YP_004097550.1 KEGG: kfl:Kfla_2351 hypothetical protein; SPTR: uncharacterized protein YP_004097551.1 KEGG: sgr:SGR_4358 hypothetical protein; SPTR: uncharacterized protein YP_004097552.1 InterPro IPR000182; KEGG: sna:Snas_5102 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004097553.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006091: IPR006090; KEGG: kse:Ksed_26500 acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase N terminal; acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain YP_004097554.1 COGs: COG0400 esterase; InterPro IPR003140; KEGG: nca:Noca_2054 phospholipase/carboxylesterase; PFAM: phospholipase/carboxylesterase; SPTR: phospholipase/carboxylesterase; PFAM: phospholipase/carboxylesterase YP_004097555.1 COGs: COG2085 dinucleotide-binding protein; InterPro IPR004455; KEGG: rxy:Rxyl_1793 reduced coenzyme F420:NADP oxidoreductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; SPTR: reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent YP_004097556.1 COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: scb:SCAB_86641 MarR family regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: transcriptional regulator; PFAM: MarR family YP_004097557.1 KEGG: kfl:Kfla_0348 hypothetical protein; SPTR: uncharacterized protein YP_004097558.1 COGs: COG2247 cell wall-binding domain; InterPro IPR002502: IPR007253: IPR006619; KEGG: mcu:HMPREF0573_11044 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; cell wall binding repeat 2-containing protein; SMART: Animal peptidoglycan recognition protein PGRP; N-acetylmuramoyl-L-alanine amidase family 2; SPTR: LytC; PFAM: N-acetylmuramoyl-L-alanine amidase; cell wall binding repeat 2 YP_004097559.1 KEGG: fra:Francci3_2257 hypothetical protein; SPTR: uncharacterized protein YP_004097560.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: srm:SRM_00813 conserved hypothetical protein containing nucleotidyltransferase domain; PFAM: DNA polymerase beta domain protein region; SPTR: uncharacterized protein; manually curated; PFAM: nucleotidyltransferase domain YP_004097561.1 COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: afo:Afer_0034 protein of unknown function DUF86; PFAM: protein of unknown function DUF86; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF86 YP_004097562.1 KEGG: ecx:EcHS_A2423 hypothetical protein; SPTR: uncharacterized protein YP_004097563.1 COGs: COG0717 deoxycytidine deaminase; InterPro IPR011962: IPR008180; KEGG: kse:Ksed_26270 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; SPTR: deoxycytidine triphosphate deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase YP_004097564.1 InterPro IPR000073; KEGG: sco:SCO0635 hypothetical protein; PFAM: alpha/beta hydrolase fold; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold YP_004097565.1 COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR003439: IPR003593: IPR017871; KEGG: kse:Ksed_26260 glycine betaine/L-proline transport ATP binding subunit; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding subunit; PFAM: ABC transporter; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit YP_004097566.1 COGs: COG1174 ABC-type proline/glycine betaine transport systems permease; InterPro IPR000515; KEGG: nml:Namu_1405 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type glycine betaine transport, permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097567.1 COGs: COG1174 ABC-type proline/glycine betaine transport systems permease; InterPro IPR000515; KEGG: kse:Ksed_26240 ABC-type proline/glycine betaine transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC transporter-associated permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097568.1 COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transporter (osmoprotectant binding protein); InterPro IPR007210; KEGG: nml:Namu_1403 substrate-binding region of ABC-type glycine betaine transporter; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SPTR: ABC-type glycine betaine transport, substrate-binding protein; PFAM: substrate binding domain of ABC-type glycine betaine transporter YP_004097569.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: kse:Ksed_22440 predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold; SPTR: alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold YP_004097570.1 COGs: COG2124 cytochrome P450; InterPro IPR001128: IPR017972: IPR002397; KEGG: gob:Gobs_1911 cytochrome P450; PFAM: cytochrome P450; SPTR: cytochrome P450; PFAM: cytochrome P450 YP_004097571.1 KEGG: rrs:RoseRS_4025 NB-ARC domain-containing protein; SPTR: hypothetical protein YP_004097572.1 InterPro IPR019781: IPR001680: IPR019782; KEGG: gob:Gobs_1160 WD40 repeat, subgroup; PFAM: WD40 repeat, subgroup; SPTR: WD40 repeat, subgroup; PFAM: WD domain, G-beta repeat YP_004097574.1 KEGG: kfl:Kfla_3734 hypothetical protein; SPTR: uncharacterized protein YP_004097575.1 COGs: COG3284 transcriptional activator of acetoin/glycerol metabolism; InterPro IPR003018: IPR001867; KEGG: nca:Noca_2091 transcriptional regulator; PFAM: transcriptional regulator domain-containing protein; GAF domain protein; SPTR: transcriptional regulator; manually curated YP_004097576.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: nca:Noca_2092 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase (NAD(+)); PFAM: aldehyde dehydrogenase family YP_004097577.1 COGs: COG3564 conserved hypothetical protein; InterPro IPR008497; KEGG: sen:SACE_2914 hypothetical protein; PFAM: protein of unknown function DUF779; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF779) YP_004097578.1 COGs: COG0330 membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107: IPR001972; KEGG: pac:PPA1973 stomatin/prohibitin-like protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: uncharacterized protein; PFAM: SPFH domain / Band 7 family YP_004097579.1 KEGG: mpa:MAP3182 hypothetical protein; SPTR: uncharacterized protein YP_004097580.1 COGs: COG3256 nitric oxide reductase large subunit; InterPro IPR000883; KEGG: mjl:Mjls_1539 nitric-oxide reductase subunit B; PFAM: cytochrome C oxidase subunit I; SPTR: nitric oxide reductase; PFAM: cytochrome C and Quinol oxidase polypeptide I YP_004097581.1 KEGG: nca:Noca_3173 hypothetical protein; SPTR: uncharacterized protein YP_004097582.1 KEGG: nca:Noca_3174 hypothetical protein; SPTR: uncharacterized protein YP_004097583.1 KEGG: nca:Noca_3175 hypothetical protein; SPTR: uncharacterized protein YP_004097584.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR017900: IPR017896; KEGG: kse:Ksed_26190 Fe-S oxidoreductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: iron-sulphur-binding reductase; PFAM: Cysteine-rich domain YP_004097585.1 COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859: IPR001216; KEGG: bcv:Bcav_2609 cysteine synthase A; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases YP_004097586.1 COGs: COG1045 serine acetyltransferase; InterPro IPR001451: IPR005881: IPR018357; KEGG: bfa:Bfae_12330 serine O-acetyltransferase; SPTR: serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase YP_004097587.1 COGs: COG0294 dihydropteroate synthase; InterPro IPR000489: IPR006390; KEGG: pfr:PFREUD_02120 dihydropteroate synthase ((2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl- diphosphate:4-am inobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase); PFAM: dihydropteroate synthase DHPS; PRIAM: dihydropteroate synthase; SPTR: dihydropteroate synthase ((2-amino-4-hydroxy-7, 8-dihydropteridin-6-yl)methyl-diphosphate:4- aminobenzoate 2-amino-4-hydroxydihydropteridine-6- methenyltransferase); TIGRFAM: dihydropteroate synthase; manually curated; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_004097588.1 COGs: COG1278 Cold shock protein; InterPro IPR002059: IPR012156: IPR011129: IPR019844; KEGG: xce:Xcel_1267 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: Cold shock protein; PFAM: 'Cold-shock' DNA-binding domain YP_004097589.1 COGs: COG1316 transcriptional regulator; InterPro IPR004474; KEGG: kse:Ksed_26120 cell envelope-related function transcriptional attenuator common domain protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004097590.1 COGs: COG1316 transcriptional regulator; InterPro IPR004474; KEGG: kse:Ksed_26120 cell envelope-related function transcriptional attenuator common domain protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004097591.1 KEGG: sma:SAV_7098 hypothetical protein; SPTR: uncharacterized protein YP_004097592.1 COGs: COG1274 phosphoenolpyruvate carboxykinase (GTP); InterPro IPR008209: IPR022272: IPR018091; KEGG: gob:Gobs_4876 phosphoenolpyruvate carboxykinase (GTP); PFAM: phosphoenolpyruvate carboxykinase (GTP); PRIAM: phosphoenolpyruvate carboxykinase (GTP); SPTR: phosphoenolpyruvate carboxykinase [GTP]; PFAM: phosphoenolpyruvate carboxykinase YP_004097593.1 InterPro IPR010093; KEGG: sti:Sthe_2833 phage transcriptional regulator, AlpA; SPTR: Phage transcriptional regulator, AlpA; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family YP_004097594.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nml:Namu_0644 integrase; PFAM: integrase; SPTR: Integrase; PFAM: Phage integrase family YP_004097595.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: gbr:Gbro_4728 integrase; PFAM: integrase; integrase; SPTR: transposase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family YP_004097596.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: fal:FRAAL3336 hypothetical protein; SPTR: uncharacterized protein YP_004097597.1 KEGG: bsu:BSU34080 ABC transporter (permease); SPTR: uncharacterized protein yvfS YP_004097598.1 KEGG: ara:Arad_4550 hypothetical protein; SPTR: uncharacterized protein YP_004097599.1 KEGG: sro:Sros_2904 hypothetical protein; SPTR: uncharacterized protein YP_004097600.1 COGs: COG3422 conserved hypothetical protein; InterPro IPR010879; KEGG: kfl:Kfla_0634 protein of unknown function DUF1508; PFAM: protein of unknown function DUF1508; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1508) YP_004097601.1 KEGG: xce:Xcel_3445 hypothetical protein; SPTR: uncharacterized protein YP_004097602.1 KEGG: xce:Xcel_3427 hypothetical protein; SPTR: uncharacterized protein YP_004097603.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: rha:RHA1_ro00013 transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: transposase; PFAM: transposase YP_004097604.1 KEGG: mgi:Mflv_0689 transposase IS116/IS110/IS902 family protein; SPTR: IS110 family transposase; PFAM: transposase YP_004097605.1 COGs: COG2247 cell wall-binding domain; InterPro IPR018532: IPR007253; KEGG: sna:Snas_5967 hypothetical protein; PFAM: Domain of unknown function DUF1994; cell wall binding repeat 2-containing protein; SPTR: uncharacterized protein; PFAM: cell wall binding repeat 2; Domain of unknown function (DUF1994) YP_004097606.1 KEGG: oaa:100084570 similar to Astacin-like metallo-endopeptidase (M12 family) YP_004097607.1 COGs: COG4993 glucose dehydrogenase; InterPro IPR019551: IPR002372: IPR018391; KEGG: scl:sce5403 polyvinylalcohol dehydrogenase; PFAM: pyrrolo-quinoline quinone repeat-containing protein; PQQ-dependent enzyme-like; SMART: pyrrolo-quinoline quinone beta-propeller repeat; SPTR: polyvinylalcohol dehydrogenase; PFAM: pyrrolo-quinoline quinone coenzyme N-terminus; PQQ enzyme repeat YP_004097608.1 KEGG: dol:Dole_1753 FG-GAP repeat-containing protein; SPTR: Amyloid protein a variant 2 YP_004097609.1 InterPro IPR001304; KEGG: plt:Plut_0367 VCBS; PFAM: C-type lectin domain protein; SMART: C-type lectin domain protein; SPTR: uncharacterized protein; PFAM: Lectin C-type domain YP_004097610.1 COGs: COG3386 gluconolactonase; InterPro IPR013658: IPR005511; KEGG: rer:RER_51080 lactone hydrolase; PFAM: SMP-30/gluconolaconase/LRE-like region-containing protein; SPTR: SMP-30/gluconolaconase/LRE domain protein; PFAM: SMP-30/gluconolaconase/LRE-like region YP_004097611.1 InterPro IPR002934; KEGG: xce:Xcel_2886 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase beta domain protein region; PFAM: nucleotidyltransferase domain YP_004097612.1 InterPro IPR007842; KEGG: nca:Noca_3210 hypothetical protein; PFAM: HEPN domain protein; SPTR: uncharacterized protein; PFAM: HEPN domain YP_004097613.1 KEGG: kfl:Kfla_4023 RNA polymerase, sigma-24 subunit, ECF subfamily; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily YP_004097614.1 COGs: COG3284 transcriptional activator of acetoin/glycerol metabolism; InterPro IPR002078: IPR003018: IPR002197; KEGG: sma:SAV_1392 transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SPTR: transcriptional regulator; PFAM: Bacterial regulatory protein, Fis family YP_004097615.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: sma:SAV_1393 alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004097616.1 COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: sma:SAV_1394 ABC transporter solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: multiple sugar ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004097617.1 COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: sma:SAV_1395 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: multiple sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097618.1 COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: sma:SAV_1396 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: multiple sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097619.1 COGs: COG3839 ABC-type sugar transporters ATPase components; InterPro IPR003439: IPR013611: IPR003593: IPR017871; KEGG: sma:SAV_1397 sugar ABC transporter ATP-binding protein; PFAM: ABC transporter related; transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: multiple sugar ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004097620.1 COGs: COG3839 ABC-type sugar transporters ATPase components; InterPro IPR003439: IPR013611: IPR003593; KEGG: sma:SAV_1398 sugar ABC transporter ATP-binding protein; PFAM: ABC transporter; transport-associated OB domain-containing protein; SMART: ATPase AAA; SPTR: multiple sugar ABC transporter ATP-binding protein; PFAM: ABC transporter; TOBE domain YP_004097621.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: rop:ROP_pROB01-03010 methyltransferase; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004097622.1 KEGG: fre:Franean1_3436 hypothetical protein; SPTR: uncharacterized protein YP_004097623.1 KEGG: lbz:LbrM25_V2.0520 hypothetical protein YP_004097624.1 COGs: COG3666 transposase and inactivated derivatives; InterPro IPR002559; KEGG: cef:CE2290 hypothetical protein; PFAM: transposase IS4 family protein; SPTR: uncharacterized protein; PFAM: transposase DDE domain; transposase domain (DUF772) YP_004097625.1 KEGG: fre:Franean1_3436 hypothetical protein; SPTR: uncharacterized protein YP_004097626.1 COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR007712: IPR012753; KEGG: gob:Gobs_3715 addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; SPTR: Addiction module toxin, RelE/StbE family; TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family YP_004097627.1 InterPro IPR006442; KEGG: aau:AAur_0708 prevent-host-death protein; SPTR: Prevent-host-death protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004097628.1 COGs: COG3654 Prophage maintenance system killer protein; InterPro IPR003812: IPR006440; KEGG: kra:Krad_2677 death-on-curing family protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: Death-on-curing family protein; TIGRFAM: death-on-curing family protein; PFAM: Fic/DOC family; TIGRFAM: death-on-curing family protein YP_004097629.1 KEGG: kra:Krad_2676 CopG domain protein DNA-binding domain protein; SPTR: CopG domain protein DNA-binding domain protein; manually curated; PFAM: Ribbon-helix-helix protein, copG family YP_004097630.1 COGs: COG2188 transcriptional regulators; InterPro IPR011663; KEGG: nda:Ndas_2625 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; SPTR: GntR family transcriptional regulator; manually curated; PFAM: UTRA domain YP_004097631.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020904: IPR020845; KEGG: svi:Svir_34080 AMP-binding domain protein; PFAM: AMP-dependent synthetase and ligase; SPTR: acyl-CoA synthetase; PFAM: AMP-binding enzyme YP_004097632.1 KEGG: sen:SACE_6800 hypothetical protein; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2157) YP_004097633.1 KEGG: cre:CHLREDRAFT_6783 SNF2 superfamily protein; SPTR: uncharacterized protein YP_004097634.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: chl:Chy400_1182 coenzyme F390 synthetase-like protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Coenzyme F390 synthetase-like protein; PFAM: AMP-binding enzyme YP_004097635.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: chl:Chy400_1183 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004097636.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR000709; KEGG: rca:Rcas_0542 ABC-type branched-chain amino acid transporters periplasmic component-like protein; SPTR: ABC-type branched-chain amino acid transporters periplasmic component-like protein YP_004097637.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: chl:Chy400_1185 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004097638.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: chl:Chy400_1186 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004097639.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: rrs:RoseRS_0623 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme YP_004097640.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593; KEGG: rrs:RoseRS_0622 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004097641.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain YP_004097642.1 COGs: COG0365 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme YP_004097643.1 COGs: COG2132 multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase YP_004097644.1 COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148: IPR015945: IPR008909: IPR001278: IPR 001412; KEGG: tfu:Tfu_0269 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase YP_004097645.1 COGs: COG3710 DNA-binding winged-HTH domains; InterPro IPR001867: IPR000073; KEGG: msm:MSMEG_3856 transcriptional regulator, CadC; PFAM: transcriptional regulator domain-containing protein; alpha/beta hydrolase fold; SPTR: CadC family transcriptional regulator; PFAM: transcriptional regulatory protein, C terminal; alpha/beta hydrolase fold YP_004097646.1 COGs: COG0644 dehydrogenase (flavoprotein); InterPro IPR006076: IPR003042; KEGG: sen:SACE_3335 monooxygenase, FAD-binding; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase, FAD-binding; PFAM: FAD binding domain YP_004097647.1 COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: ade:Adeh_2254 OsmC-like protein; PFAM: OsmC family protein; SPTR: OsmC-like protein; PFAM: OsmC-like protein YP_004097648.1 KEGG: art:Arth_2347 hypothetical protein; SPTR: uncharacterized protein YP_004097649.1 COGs: COG3118 thioredoxin domain-containing protein; InterProIPR017936: IPR013766: IPR017937: IPR006662: IPR 005746; KEGG: nml:Namu_1297 thioredoxin; PFAM: thioredoxin domain-containing protein; SPTR: thioredoxin; TIGRFAM: thioredoxin; PFAM: thioredoxin; TIGRFAM: thioredoxin YP_004097650.1 COGs: COG3439 conserved hypothetical protein; InterPro IPR005180: IPR016796; KEGG: nml:Namu_0357 protein of unknown function DUF302; PFAM: protein of unknown function DUF302; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF302 YP_004097651.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: nca:Noca_4293 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004097652.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753: IPR018376; KEGG: nml:Namu_0873 enoyl-CoA hydratase/isomerase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase/isomerase; PFAM: enoyl-CoA hydratase/isomerase family YP_004097653.1 COGs: COG0183 acetyl-CoA acetyltransferase; InterProIPR020616: IPR020617: IPR002155: IPR020615: IPR 020610: IPR001412: IPR020613: IPR012793; KEGG: nml:Namu_0875 beta-ketoadipyl CoA thiolase; PFAM: thiolase-like; SPTR: beta-ketoadipyl CoA thiolase; TIGRFAM: beta-ketoadipyl CoA thiolase; acetyl-CoA acetyltransferase; PFAM: thiolase, C-terminal domain; thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; beta-ketoadipyl CoA thiolase YP_004097654.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: nca:Noca_4296 cyclohexanecarboxylate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; TIGRFAM: cyclohexanecarboxylate-CoA ligase YP_004097655.1 COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198: IPR020904: IPR002347; KEGG: nml:Namu_0877 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004097656.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: nca:Noca_4298 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain; TIGRFAM: cyclohexanecarboxyl-CoA dehydrogenase YP_004097657.1 COGs: COG0447 dihydroxynaphthoic acid synthase; InterPro IPR001753: IPR018376; KEGG: nca:Noca_4299 1,4-dihydroxy-2-naphthoate synthase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: 1,4-dihydroxy-2-naphthoate synthase; PFAM: enoyl-CoA hydratase/isomerase family; TIGRFAM: naphthoate synthase (dihydroxynaphthoic acid synthetase) YP_004097658.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647: IPR006665; KEGG: nml:Namu_0880 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family YP_004097659.1 COGs: COG2181 nitrate reductase subunit gamma; InterPro IPR003816; KEGG: nca:Noca_1349 respiratory nitrate reductase gamma subunit; PFAM: nitrate reductase subunit gamma; PRIAM: nitrate reductase; SPTR: Respiratory nitrate reductase subunit gamma; TIGRFAM: respiratory nitrate reductase, subunit gamma; PFAM: nitrate reductase subunit gamma; TIGRFAM: respiratory nitrate reductase, subunit gamma YP_004097660.1 COGs: COG2180 nitrate reductase subunit delta; InterPro IPR020945: IPR003765; KEGG: nca:Noca_1348 respiratory nitrate reductase chaperone NarJ; PFAM: TorD-like chaperone; SPTR: nitrate reductase subunit delta; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: nitrate reductase subunit delta; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone YP_004097661.1 COGs: COG1140 nitrate reductase subunit beta; InterPro IPR017896: IPR006547; KEGG: kfl:Kfla_4151 nitrate reductase, beta subunit; SPTR: nitrate reductase subunit beta; TIGRFAM: nitrate reductase, subunit beta; TIGRFAM: nitrate reductase subunit beta YP_004097662.1 COGs: COG5013 nitrate reductase subunit alpha; InterPro IPR006656: IPR006657: IPR006655: IPR006468; KEGG: nca:Noca_1346 respiratory nitrate reductase subunit alpha apoprotein; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; PRIAM: nitrate reductase; SPTR: Respiratory nitrate reductase subunit alpha apoprotein; TIGRFAM: nitrate reductase, subunit alpha; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: respiratory nitrate reductase, subunit alpha YP_004097663.1 COGs: COG2345 transcriptional regulator protein; KEGG: nca:Noca_2106 transcriptional regulator; SPTR: transcriptional regulator; PFAM: IclR helix-turn-helix domain YP_004097664.1 COGs: COG2223 nitrate/nitrite transporter; InterPro IPR011701: IPR001412; KEGG: stp:Strop_0176 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004097665.1 COGs: COG2223 nitrate/nitrite transporter; KEGG: saq:Sare_0190 nitrate/nitrite transporter-like protein; SPTR: nitrate/nitrite transporter-like protein; PFAM: Major Facilitator Superfamily YP_004097666.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753: IPR018376; KEGG: cur:cur_1929 enoyl-CoA hydratase/isomerase family protein; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase family YP_004097667.1 COGs: COG3288 NAD/NADP transhydrogenase alpha subunit; InterPro IPR007886: IPR007698: IPR008143: IPR004571; KEGG: mva:Mvan_0120 NAD(P) transhydrogenase subunit alpha; PFAM: alanine dehydrogenase/PNT domain protein; SPTR: NAD(P) transhydrogenase, alpha subunit; TIGRFAM: NAD(P) transhydrogenase, subunit alpha; PFAM: alanine dehydrogenase/PNT, C-terminal domain; alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: NAD(P) transhydrogenase, subunit alpha YP_004097668.1 COGs: COG1282 NAD/NADP transhydrogenase beta subunit; InterPro IPR004003: IPR012136; KEGG: cfl:Cfla_0904 NAD(P)(+) transhydrogenase (AB-specific); PFAM: NAD(P) transhydrogenase beta subunit; PRIAM: NAD(P)(+) transhydrogenase (AB-specific); SPTR: NAD(P) transhydrogenase subunit beta; PFAM: NAD(P) transhydrogenase subunit beta YP_004097669.1 InterPro IPR001387; KEGG: bcv:Bcav_3642 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; manually curated; PFAM: Helix-turn-helix YP_004097670.1 KEGG: cfl:Cfla_0847 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial membrane flanked domain YP_004097671.1 KEGG: cfl:Cfla_0846 hypothetical protein; SPTR: uncharacterized protein YP_004097672.1 COGs: COG5459 rRNA methylase; InterPro IPR015324; KEGG: kfl:Kfla_2484 ribosomal small subunit Rsm22; PFAM: ribosomal small subunit Rsm22; SPTR: ribosomal small subunit Rsm22; PFAM: Mitochondrial small ribosomal subunit Rsm22 YP_004097673.1 COGs: COG0035 uracil phosphoribosyltransferase; InterPro IPR000836: IPR005765; KEGG: nca:Noca_0275 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: uracil phosphoribosyltransferase; TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase YP_004097674.1 COGs: COG0590 cytosine/adenosine deaminase; InterPro IPR002125; KEGG: cfl:Cfla_0483 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: CMP/dCMP deaminase zinc-binding protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004097675.1 COGs: COG1893 Ketopantoate reductase; InterPro IPR013332: IPR013752; KEGG: gob:Gobs_3881 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase; SPTR: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase YP_004097676.1 KEGG: rca:Rcas_3148 hydrogenase (NiFe) small subunit HydA YP_004097677.1 InterPro IPR013216; KEGG: afw:Anae109_4039 methyltransferase type 12; PFAM: methyltransferase type 11; SPTR: methyltransferase type 12; PFAM: methyltransferase domain YP_004097678.1 COGs: COG0404 glycine cleavage system protein T (aminomethyltransferase); InterPro IPR006076: IPR006222: IPR013977; KEGG: nca:Noca_3838 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; SPTR: FAD dependent oxidoreductase; PFAM: Aminomethyltransferase folate-binding domain; glycine cleavage T-protein C-terminal barrel domain; FAD dependent oxidoreductase; TIGRFAM: glycine cleavage system T protein YP_004097679.1 KEGG: dze:Dd1591_1431 major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1 YP_004097680.1 KEGG: cai:Caci_6370 short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR YP_004097681.1 COGs: COG3899 ATPase; InterPro IPR000792; KEGG: sen:SACE_5520 LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family YP_004097682.1 KEGG: pol:Bpro_2435 hypothetical protein; SPTR: uncharacterized protein YP_004097683.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: cwo:Cwoe_0591 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004097684.1 InterPro IPR016047; KEGG: pfr:PFREUD_17710 peptidase; PFAM: peptidase M23; SPTR: peptidase; PFAM: peptidase family M23 YP_004097685.1 KEGG: sna:Snas_3206 hypothetical protein; SPTR: uncharacterized protein YP_004097686.1 COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: gme:Gmet_1711 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; SPTR: L-carnitine dehydratase/bile acid-inducible protein F; PFAM: CoA-transferase family III YP_004097687.1 COGs: COG0433 ATPase; InterPro IPR008571; KEGG: krh:KRH_08710 hypothetical protein; PFAM: protein of unknown function DUF853 NPT hydrolase; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF853) YP_004097688.1 InterPro IPR014447; KEGG: xce:Xcel_0235 hypothetical protein; SPTR: uncharacterized protein YP_004097689.1 KEGG: kse:Ksed_25980 hypothetical protein; SPTR: membrane protein YP_004097690.1 COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: kfl:Kfla_5624 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Probable ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097691.1 COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: kfl:Kfla_5625 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component YP_004097692.1 COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: kfl:Kfla_5626 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004097693.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: art:Arth_2897 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: carbohydrate kinase; PFAM: pfkB family carbohydrate kinase YP_004097694.1 COGs: COG1486 alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088: IPR019802; KEGG: sgr:SGR_1058 6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: 6-phospho-beta-glucosidase; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004097695.1 COGs: COG4409 Neuraminidase (sialidase); InterPro IPR000421: IPR017909: IPR012680; KEGG: sgr:SGR_6429 neuramidase; PFAM: coagulation factor 5/8 type domain protein; Laminin G sub domain 2; SPTR: Sialidase; PFAM: F5/8 type C domain; BNR/Asp-box repeat; NPCBM-associated, NEW3 domain of alpha-galactosidase YP_004097696.1 COGs: COG0078 ornithine carbamoyltransferase; InterPro IPR006132: IPR006131: IPR002292: IPR006130; KEGG: sma:SAV_2319 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; SPTR: ornithine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_004097697.1 InterPro IPR011701: IPR001958; KEGG: nca:Noca_3966 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004097698.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: sen:SACE_4438 DeoR-type transcriptional regulator; PFAM: major facilitator superfamily MFS_1; SPTR: integral membrane protein; PFAM: Major Facilitator Superfamily YP_004097699.1 COGs: COG4552 acetyltransferase involved in intracellular survival and related acetyltransferase; InterPro IPR000182; KEGG: kfl:Kfla_4406 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004097700.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR014021: IPR001650: IPR011545: IPR014001: IPR 018329; KEGG: sro:Sros_5632 ATP-dependent DNA helicase RecQ; PFAM: helicase; DEAD/DEAH box helicase; SMART: helicase; DEAD-like helicase; SPTR: ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family YP_004097701.1 KEGG: sgr:SGR_6360 hypothetical protein; SPTR: uncharacterized protein YP_004097702.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR003593; KEGG: cms:CMS_2559 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ATP-binding protein of sugar ABC transporter; PFAM: ABC transporter YP_004097703.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003959: IPR003593: IPR012763; KEGG: rsa:RSal33209_3356 DNA polymerase III subunits gamma and tau; PFAM: ATPase AAA central domain protein; SMART: ATPase AAA; SPTR: DNA polymerase III subunits gamma and tau; TIGRFAM: DNA polymerase III subunits gamma and tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III subunit gamma and tau YP_004097704.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: nca:Noca_2043 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase, S-adenosyl-L-methionine (SAM)-MTase protein; PFAM: methyltransferase domain YP_004097705.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123: IPR000276; KEGG: nca:Noca_1494 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acylglycerol-3-phosphate O-acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004097706.1 COGs: COG0353 recombinational DNA repair protein (RecF pathway); InterPro IPR015967: IPR006171: IPR000093: IPR006154; KEGG: bcv:Bcav_0549 recombination protein RecR; PFAM: TOPRIM domain-containing protein; Zinc finger C4-type, RecR; SMART: Toprim sub domain-containing protein; SPTR: recombination protein RecR; TIGRFAM: recombination protein RecR; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_004097707.1 KEGG: kra:Krad_0464 hypothetical protein; SPTR: uncharacterized protein YP_004097708.1 InterPro IPR001387; KEGG: bcv:Bcav_3642 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004097709.1 COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR018042: IPR005260: IPR 001341; KEGG: tcu:Tcur_4886 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase YP_004097710.1 KEGG: hsa:90378 sterile alpha motif domain containing 1; SPTR: Atherin YP_004097711.1 KEGG: sro:Sros_2455 hypothetical protein; SPTR: uncharacterized protein YP_004097712.1 KEGG: amd:AMED_6555 hypothetical protein; SPTR: uncharacterized protein YP_004097713.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; ANTAR domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004097714.1 KEGG: fre:Franean1_3999 hemerythrin HHE cation binding domain-containing protein; SPTR: hemerythrin HHE cation binding region YP_004097715.1 COGs: COG3569 Topoisomerase IB; InterPro IPR001631; KEGG: amd:AMED_4291 DNA topoisomerase IB; SPTR: uncharacterized protein; PFAM: Eukaryotic DNA topoisomerase I, catalytic core YP_004097716.1 COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR002937: IPR006076; KEGG: nml:Namu_3691 FAD dependent oxidoreductase; PFAM: amine oxidase; FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase YP_004097717.1 KEGG: nml:Namu_2441 hypothetical protein; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport YP_004097718.1 InterPro IPR012312; KEGG: nda:Ndas_5558 hemerythrin HHE cation binding domain protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin HHE cation binding domain protein; PFAM: hemerythrin HHE cation binding domain YP_004097719.1 KEGG: bcv:Bcav_3839 hypothetical protein; SPTR: uncharacterized protein YP_004097721.1 KEGG: nca:Noca_1877 hypothetical protein; SPTR: uncharacterized protein YP_004097722.1 COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; KEGG: nca:Noca_1876 natural resistance-associated macrophage protein; SPTR: Natural resistance-associated macrophage protein; PFAM: Natural resistance-associated macrophage protein YP_004097723.1 KEGG: amd:AMED_3278 hypothetical protein; SPTR: uncharacterized protein YP_004097724.1 COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR017941: IPR006076; KEGG: nda:Ndas_1353 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; SPTR: FAD dependent oxidoreductase; PFAM: Rieske [2Fe-2S] domain; FAD dependent oxidoreductase YP_004097725.1 COGs: COG0366 glycosidase; InterPro IPR006047: IPR006589; KEGG: mrd:Mrad2831_0315 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: alpha amylase catalytic region; PFAM: alpha amylase, catalytic domain; TIGRFAM: trehalose synthase YP_004097726.1 COGs: COG1501 alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: bcv:Bcav_3837 alpha-glucosidase; PFAM: glycoside hydrolase family 31; PRIAM: alpha-glucosidase; SPTR: alpha-glucosidase; PFAM: glycosyl hydrolases family 31 YP_004097727.1 KEGG: nfa:nfa23340 hypothetical protein; SPTR: uncharacterized protein YP_004097728.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterPro IPR003439: IPR017940: IPR003593; KEGG: nca:Noca_2806 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter YP_004097729.1 COGs: COG0366 glycosidase; InterPro IPR006047: IPR006589; KEGG: mgi:Mflv_3723 alpha amylase, catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: alpha amylase, catalytic region; PFAM: alpha amylase, catalytic domain; TIGRFAM: trehalose synthase YP_004097730.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019945; KEGG: mgi:Mflv_3722 dehydrogenase protein; SPTR: dehydrogenase protein; TIGRFAM: F420-dependent oxidoreductase, G6PDH family; PFAM: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase, G6PDH family YP_004097731.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR020904: IPR002347; KEGG: krh:KRH_14530 oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: oxidoreductase; PFAM: short chain dehydrogenase YP_004097732.1 COGs: COG2170 conserved hypothetical protein; InterPro IPR006336: IPR011793; KEGG: sgr:SGR_459 carboxylate-amine ligase; PFAM: glutamate--cysteine ligase; SPTR: carboxylate-amine ligase SACT1DRAFT_0179; PFAM: glutamate-cysteine ligase family 2(GCS2); TIGRFAM: uncharacterized enzyme YP_004097733.1 KEGG: der:Dere_GG19401 GG19401 gene product from transcript GG19401-RA; SPTR: uncharacterized protein YP_004097734.1 KEGG: mva:Mvan_4746 hypothetical protein; SPTR: uncharacterized protein YP_004097735.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR007627: IPR007624: IPR007630: IPR000943: IPR 014322: IPR014284; KEGG: nca:Noca_1393 sigma-70 region 4 domain-containing protein; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: Sigma-70 region 4 domain protein; TIGRFAM: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily YP_004097736.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: mkm:Mkms_4430 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004097737.1 InterPro IPR015018; KEGG: bcv:Bcav_4116 hypothetical protein; PFAM: Domain of unknown function DUF1905; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1905) YP_004097738.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: cmi:CMM_0741 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: integral membrane protein; PFAM: Domain of unknown function DUF20 YP_004097739.1 COGs: COG1502 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: amd:AMED_4111 hypothetical protein; PFAM: phospholipase D/transphosphatidylase; SPTR: phospholipase D; PFAM: phospholipase D Active site motif YP_004097740.1 KEGG: nca:Noca_2801 hypothetical protein; SPTR: uncharacterized protein YP_004097741.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: kse:Ksed_25470 predicted phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Predicted phosphohydrolase; PFAM: Calcineurin-like phosphoesterase YP_004097742.1 COGs: COG1610 conserved hypothetical protein; InterPro IPR019004; KEGG: ami:Amir_0234 GatB/YqeY domain protein; SPTR: uncharacterized protein; PFAM: Yqey-like protein YP_004097743.1 COGs: COG0744 membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kse:Ksed_25450 membrane carboxypeptidase (penicillin-binding protein); PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: transpeptidase; PFAM: Penicillin binding protein transpeptidase domain; transglycosylase YP_004097744.1 InterPro IPR003482; KEGG: ace:Acel_2003 transcription factor WhiB; PFAM: transcription factor WhiB; SPTR: transcription factor WhiB; PFAM: transcription factor WhiB YP_004097745.1 COGs: COG0003 ATPase involved in chromosome partitioning; KEGG: tbi:Tbis_0197 anion-transporting ATPase; SPTR: ion-transporting ATPase; PFAM: Anion-transporting ATPase; TC 3.A.4.1.1 YP_004097746.1 COGs: COG0003 ATPase involved in chromosome partitioning; KEGG: kfl:Kfla_0448 anion-transporting ATPase; SPTR: uncharacterized protein; PFAM: Anion-transporting ATPase; TC 3.A.4.1.1 YP_004097747.1 KEGG: nca:Noca_0019 hypothetical protein; SPTR: uncharacterized protein YP_004097748.1 KEGG: mxa:MXAN_0913 hypothetical protein; SPTR: uncharacterized protein; PFAM: prolyl oligopeptidase family YP_004097749.1 KEGG: fre:Franean1_0333 hypothetical protein; SPTR: uncharacterized protein YP_004097750.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006175; KEGG: lxx:Lxx03610 translation initiation inhibitor; PFAM: endoribonuclease L-PSP; SPTR: translation initiation inhibitor; PFAM: endoribonuclease L-PSP YP_004097751.1 InterPro IPR000086; KEGG: kse:Ksed_25420 NUDIX family protein; PFAM: NUDIX hydrolase; SPTR: NUDIX family protein; PFAM: NUDIX domain YP_004097752.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: kse:Ksed_25410 Zn-dependent hydrolase, glyoxylase; SPTR: hydrolase; PFAM: metallo-beta-lactamase superfamily YP_004097753.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR012318: IPR001808: IPR002373; KEGG: nca:Noca_0339 cyclic nucleotide-binding; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: transcriptional regulator with cyclic nucleotide-binding domain protein; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_004097754.1 COGs: COG0177 endoIII-related endonuclease; InterProIPR003265: IPR003651: IPR004035: IPR004036: IPR 005759; KEGG: kfl:Kfla_0455 endonuclease III; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; iron-sulfur cluster loop; SPTR: endonuclease III; TIGRFAM: endonuclease III; manually curated; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif; TIGRFAM: endonuclease III YP_004097755.1 InterPro IPR000086; KEGG: sgr:SGR_3331 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004097756.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR003825: IPR001254: IPR001940; KEGG: kra:Krad_0420 peptidase S1 and S6 chymotrypsin/Hap; PFAM: colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; SPTR: peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; colicin V production protein YP_004097757.1 InterPro IPR006016: IPR006015; KEGG: aau:AAur_0701 universal stress family domain-containing protein; PFAM: UspA domain-containing protein; SPTR: uncharacterized protein; PFAM: Universal stress protein family YP_004097758.1 COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: ach:Achl_0594 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: integral membrane protein; PFAM: tripartite tricarboxylate transporter TctA family YP_004097759.1 KEGG: mjl:Mjls_3247 integral membrane protein; SPTR: integral membrane protein; PFAM: tripartite tricarboxylate transporter TctB family YP_004097760.1 COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: art:Arth_1395 hypothetical protein; SPTR: secreted protein; PFAM: tripartite tricarboxylate transporter family receptor YP_004097761.1 COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; InterPro IPR005467: IPR013767: IPR003594: IPR004358; KEGG: sco:SCO1137 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: two component system histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004097762.1 COGs: COG4565 Response regulator of citrate/malate metabolism; InterPro IPR001789; KEGG: sco:SCO1136 two component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: two component system response regulator; PFAM: IclR helix-turn-helix domain; Response regulator receiver domain YP_004097763.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR010259: IPR000209; KEGG: sro:Sros_3301 serine protease; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; SPTR: serine protease; PFAM: peptidase inhibitor I9; Subtilase family YP_004097764.1 KEGG: lxx:Lxx01020 beta-lactamase related protein; SPTR: beta-lactamase related protein YP_004097765.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073: IPR000639; KEGG: tbi:Tbis_0209 alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: Hydrolase; PFAM: alpha/beta hydrolase fold YP_004097766.1 KEGG: nml:Namu_0724 protein of unknown function DUF1469; SPTR: uncharacterized protein; manually curated; PFAM: protein of unknown function (DUF1469) YP_004097767.1 COGs: COG1881 phospholipid-binding protein; InterPro IPR008914: IPR005247; KEGG: drt:Dret_1202 PEBP family protein; PFAM: PEBP family protein; SPTR: PEBP family protein; PFAM: phosphatidylethanolamine-binding protein; TIGRFAM: Raf kinase inhibitor-like protein, YbhB/YbcL family YP_004097768.1 COGs: COG0110 acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: bcv:Bcav_1182 acetyltransferase, SPTR: acetyltransferase YP_004097769.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653: IPR012749; KEGG: rer:RER_24530 TDP-4-oxo-6-deoxy-D-glucose transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: aminotransferase; TIGRFAM: TDP-4-keto-6-deoxy-D-glucose transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: TDP-4-keto-6-deoxy-D-glucose transaminase YP_004097770.1 InterPro IPR007267; KEGG: kfl:Kfla_0511 GtrA family protein; PFAM: GtrA family protein; SPTR: GtrA family protein; PFAM: GtrA-like protein YP_004097771.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: kfl:Kfla_0510 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase family 2; PFAM: glycosyl transferase family 2 YP_004097772.1 COGs: COG3004 Na+/H+ antiporter; InterPro IPR004670; KEGG: gob:Gobs_2920 Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter NhaA; SPTR: sodium/proton antiporter; TIGRFAM: Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter 1; TIGRFAM: Na+/H+ antiporter NhaA; TC 2.A.33.1.1 YP_004097773.1 InterPro IPR007047; KEGG: art:Arth_2928 Flp/Fap pilin component; PFAM: Flp/Fap pilin component; SPTR: Flp/Fap pilin component; PFAM: Flp/Fap pilin component YP_004097774.1 KEGG: ach:Achl_4441 hypothetical protein; SPTR: uncharacterized protein YP_004097775.1 InterPro IPR000169; KEGG: tcu:Tcur_1854 Flp pilus assembly protein CpaB; SPTR: uncharacterized protein; TIGRFAM: Flp pilus assembly protein CpaB YP_004097776.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: ace:Acel_0975 cobyrinic acid a,c-diamide synthase; SPTR: Probable chromosome partitioning ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004097777.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482: IPR017975; KEGG: tcu:Tcur_1852 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: Flp pilus assembly protein TadA; PFAM: type II/IV secretion system protein YP_004097778.1 COGs: COG4965 Flp pilus assembly protein TadB; InterPro IPR002035: IPR018076; KEGG: tcu:Tcur_1851 type II secretion system protein; PFAM: type II secretion system F domain; von Willebrand factor A; SMART: von Willebrand factor A; SPTR: membrane protein; PFAM: von Willebrand factor A domain; Bacterial type II secretion system protein F domain YP_004097779.1 COGs: COG2064 Flp pilus assembly protein TadC; InterPro IPR018076; KEGG: tcu:Tcur_1850 type II secretion system protein; PFAM: type II secretion system F domain; SPTR: Probable secretion system protein TadC; PFAM: Bacterial type II secretion system protein F domain YP_004097780.1 InterPro IPR003347; KEGG: gob:Gobs_3279 cupin 4 family protein; SPTR: cupin; PFAM: Cupin superfamily protein YP_004097781.1 KEGG: nml:Namu_3067 hypothetical protein; SPTR: uncharacterized protein YP_004097782.1 KEGG: cfl:Cfla_1495 aldehyde dehydrogenase; SPTR: cell division protein ftsZ YP_004097783.1 COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: bfa:Bfae_17270 predicted flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: uncharacterized protein; PFAM: NADPH-dependent FMN reductase YP_004097784.1 KEGG: nml:Namu_5325 hypothetical protein; SPTR: uncharacterized protein YP_004097785.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550: IPR005170; KEGG: ami:Amir_4979 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SPTR: uncharacterized protein; PFAM: CBS domain; Domain of unknown function DUF21; transporter associated domain YP_004097786.1 COGs: COG3187 heat shock protein; InterPro IPR005184; KEGG: rer:RER_23460 hypothetical protein; PFAM: protein of unknown function DUF306 Meta and HslJ; SPTR: uncharacterized protein; PFAM: META domain YP_004097787.1 InterPro IPR003615; KEGG: kse:Ksed_09510 HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; PFAM: HNH endonuclease; Domain of unknown function DUF222 YP_004097788.1 COGs: COG0365 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873: IPR020845: IPR011904; KEGG: bcv:Bcav_0611 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: acetate/CoA ligase; TIGRFAM: acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase YP_004097789.1 KEGG: kse:Ksed_25360 hypothetical protein; SPTR: uncharacterized protein YP_004097790.1 InterPro IPR019825; KEGG: bcv:Bcav_0618 hypothetical protein; SPTR: uncharacterized protein YP_004097791.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482: IPR017975; KEGG: kse:Ksed_25300 Flp pilus assembly protein, ATPase CpaF; PFAM: type II secretion system protein E; SPTR: Flp pilus assembly protein, ATPase CpaF; PFAM: type II/IV secretion system protein; TIGRFAM: helicase/secretion neighborhood ATPase YP_004097792.1 InterPro IPR018076; KEGG: kse:Ksed_25290 Flp pilus assembly protein TadB; PFAM: type II secretion system F domain; SPTR: Flp pilus assembly protein TadB YP_004097793.1 InterPro IPR018076; KEGG: kse:Ksed_25280 Flp pilus assembly protein TadC; PFAM: type II secretion system F domain; SPTR: uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain YP_004097794.1 KEGG: jde:Jden_2222 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004097795.1 KEGG: ske:Sked_33320 hypothetical protein; SPTR: membrane protein YP_004097796.1 KEGG: mab:MAB_0475 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: helicase/secretion neighborhood TadE-like protein YP_004097797.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cai:Caci_3768 Rrf2 family/BadM/Rrf2 family transcriptional regulator/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: uncharacterized protein; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: transcriptional regulator; TIGRFAM: rrf2 family protein ( transcriptional regulator) YP_004097798.1 COGs: COG1118 ABC-type sulfate/molybdate transport systems ATPase component; InterProIPR003439: IPR014769: IPR005116: IPR003593: IPR 017871: IPR005666; KEGG: rha:RHA1_ro01270 ABC sulfate/thiosulfate porter, ATP-binding component; PFAM: ABC transporter; TOBE domain-containing protein; SMART: ATPase AAA; SPTR: sulfate ABC transporter ATP-binding protein; TIGRFAM: sulfate ABC transporter ATPase; PFAM: ABC transporter; TOBE domain; TIGRFAM: sulfate ABC transporter ATP-binding protein YP_004097799.1 COGs: COG4208 ABC-type sulfate transporter permease component; InterPro IPR000515: IPR005667: IPR011866; KEGG: rer:RER_37540 sulfate ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: sulfate ABC transporter permease; TIGRFAM: sulfate ABC transporter inner membrane subunit CysW; sulfate ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: sulfate ABC transporter permease CysW; sulfate ABC transporter permease YP_004097800.1 COGs: COG0555 ABC-type sulfate transporter permease component; InterPro IPR000515: IPR005667: IPR011865; KEGG: rha:RHA1_ro01272 ABC sulfate/thiosulfate porter, permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: sulfate/thiosulfate ABC superfamily ATP binding cassette transporter membrane protein; TIGRFAM: sulfate ABC transporter inner membrane subunit CysT; sulfate ABC transporter inner membrane subunit; manually curated; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: sulfate ABC transporter permease; sulfate ABC transporter permease CysT YP_004097801.1 COGs: COG1613 ABC-type sulfate transporter periplasmic component; InterPro IPR006059: IPR005669; KEGG: rop:ROP_09930 sulfate ABC transporter sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: sulfate ABC transporter sulfate-binding protein; TIGRFAM: sulfate ABC transporter periplasmic sulfate-binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: sulfate/thiosulfate-binding protein YP_004097802.1 KEGG: bfa:Bfae_28470 DNA polymerase III subunit gamma/tau; SPTR: DNA polymerase III subunit gamma/tau YP_004097803.1 InterPro IPR010259: IPR000209: IPR003137: IPR007280; KEGG: kfl:Kfla_2384 protease-associated PA domain protein; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; protease-associated PA domain protein; peptidase domain protein; SPTR: Protease-associated PA domain protein; PFAM: PA domain; peptidase inhibitor I9; Subtilase family YP_004097804.1 COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR014021: IPR001650: IPR011545: IPR014001; KEGG: nca:Noca_0370 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004097805.1 COGs: COG1366 anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645: IPR003658; KEGG: kfl:Kfla_0571 anti-sigma-factor antagonist; PFAM: sulfate transporter/antisigma-factor antagonist STAS; SPTR: anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist YP_004097806.1 COGs: COG2890 methylase of polypeptide chain release factors; InterPro IPR007848: IPR002052; KEGG: kse:Ksed_25140 methyltransferase family protein; PFAM: methyltransferase small; SPTR: transferase; PFAM: methyltransferase small domain; TIGRFAM: HemK family methylases YP_004097807.1 InterPro IPR001647; KEGG: tpr:Tpau_2624 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family YP_004097808.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003439: IPR017940: IPR001140: IPR003593: IPR 017871; KEGG: kfl:Kfla_3612 ABC transporter; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter YP_004097809.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003439: IPR017940: IPR001140: IPR003593: IPR 017871; KEGG: kfl:Kfla_3611 ABC transporter transmembrane region; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter YP_004097810.1 COGs: COG0751 glycyl-tRNA synthetase beta subunit; InterPro IPR006194: IPR002310: IPR002311: IPR015944; KEGG: kfl:Kfla_5824 glycyl-tRNA synthetase subunit beta; PFAM: glycyl-tRNA synthetase subunit alpha; glycyl-tRNA synthetase subunit beta; PRIAM: glycine--tRNA ligase; SPTR: glycyl-tRNA synthetase subunit beta; TIGRFAM: glycyl-tRNA synthetase subunit beta; glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase subunit beta; glycyl-tRNA synthetase subunit alpha; TIGRFAM: glycyl-tRNA synthetase, tetrameric type subunit beta; glycyl-tRNA synthetase, tetrameric type, subunit alpha YP_004097811.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523; KEGG: rxy:Rxyl_0057 magnesium and cobalt transporter CorA; PFAM: Mg2 transporter protein CorA family protein; SPTR: Magnesium and cobalt transporter CorA; PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transporter (corA) YP_004097812.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551: IPR015358: IPR010211; KEGG: tcu:Tcur_2818 transcriptional regulator, MerR family; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR; SPTR: transcriptional regulator, MerR family; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: MerR family regulatory protein; MerR, DNA binding; TIGRFAM: redox-sensitive transcriptional activator SoxR YP_004097813.1 KEGG: aoe:Clos_0772 phosphotransferase (aminonucleoside antibiotic resistance); SPTR: phosphotransferase (Aminonucleoside antibiotic resistance); PFAM: chloramphenicol phosphotransferase-like protein YP_004097814.1 InterPro IPR000253; KEGG: kfl:Kfla_5978 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: FHA domain containing protein; PFAM: FHA domain YP_004097815.1 InterPro IPR002035; KEGG: kfl:Kfla_5977 von Willebrand factor A; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: uncharacterized protein; PFAM: von Willebrand factor A domain YP_004097816.1 COGs: COG0631 serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: kfl:Kfla_5976 protein serine/threonine phosphatase; PFAM: protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: protein serine/threonine phosphatase; PFAM: protein phosphatase 2C YP_004097817.1 COGs: COG0515 serine/threonine protein kinase; InterPro IPR000719: IPR017442: IPR020635: IPR002290; KEGG: kfl:Kfla_5975 serine/threonine protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: serine/threonine protein kinase; PFAM: protein kinase domain YP_004097818.1 KEGG: kfl:Kfla_5974 hypothetical protein; SPTR: uncharacterized protein YP_004097819.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR017909: IPR001638: IPR018313; KEGG: cfl:Cfla_3062 extracellular solute-binding protein family 3; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: extracellular solute-binding protein family 3; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004097820.1 KEGG: kfl:Kfla_5972 hypothetical protein; SPTR: uncharacterized protein YP_004097821.1 COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959: IPR003593: IPR000641; KEGG: kfl:Kfla_5971 ATPase AAA central domain protein; PFAM: ATPase AAA; SMART: ATPase AAA; SPTR: ATPase AAA central domain protein; PFAM: ATPase family associated with various cellular activities (AAA) YP_004097822.1 KEGG: kfl:Kfla_5970 hypothetical protein; SPTR: uncharacterized protein YP_004097823.1 COGs: COG3853 Uncharacterized protein involved in tellurite resistance; InterPro IPR008863; KEGG: kfl:Kfla_5969 toxic anion resistance family protein; PFAM: toxic anion resistance family protein; SPTR: Toxic anion resistance family protein; PFAM: Toxic anion resistance protein (TelA) YP_004097824.1 COGs: COG3384 conserved hypothetical protein; InterPro IPR004183: IPR014436; KEGG: art:Arth_0218 extradiol ring-cleavage dioxygenase III subunit B; PFAM: extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: uncharacterized protein; PFAM: Catalytic LigB subunit of aromatic ring-opening dioxygenase YP_004097825.1 COGs: COG0550 Topoisomerase IA; InterProIPR006171: IPR013497: IPR006154: IPR003601: IPR 003602: IPR000380: IPR005733; KEGG: kse:Ksed_25040 DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_004097826.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: kse:Ksed_25150 uncharacterized LmbE-like protein; PFAM: LmbE family protein; SPTR: Uncharacterized LmbE-like protein; PFAM: GlcNAc-PI de-N-acetylase YP_004097827.1 InterPro IPR003033; KEGG: saq:Sare_0143 sterol-binding domain-containing protein; PFAM: sterol-binding domain protein; SPTR: sterol-binding domain-containing protein; PFAM: SCP-2 sterol transfer family YP_004097828.1 COGs: COG2838 Monomeric isocitrate dehydrogenase; InterPro IPR004436; KEGG: sgr:SGR_1224 isocitrate dehydrogenase; PFAM: isocitrate dehydrogenase NADP-dependent monomeric type; PRIAM: isocitrate dehydrogenase (NADP(+)); SPTR: isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type YP_004097829.1 COGs: COG1680 beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: kra:Krad_3287 beta-lactamase; PFAM: beta-lactamase; SPTR: beta-lactamase; PFAM: beta-lactamase YP_004097830.1 COGs: COG2909 ATP-dependent transcriptional regulator protein; InterPro IPR000792; KEGG: pna:Pnap_3341 response regulator receiver protein; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: LuxR family transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family YP_004097831.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: mlu:Mlut_14300 transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: transposase; PFAM: transposase YP_004097833.1 COGs: COG1834 N-dimethylarginine dimethylaminohydrolase; InterPro IPR003198; KEGG: kfl:Kfla_3423 dimethylargininase; PFAM: amidinotransferase; PRIAM: dimethylargininase; SPTR: dimethylarginine dimethylaminohydrolase; PFAM: Amidinotransferase YP_004097834.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sro:Sros_3515 LysR family regulatory protein; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: LysR family regulatory protein; manually curated; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_004097835.1 COGs: COG3227 Zinc metalloprotease (elastase); InterPro IPR011096: IPR013856: IPR001570: IPR007484; KEGG: sro:Sros_3786 zinc metalloprotease (elastase)-like protein; PFAM: peptidase M28; peptidase M4 thermolysin; propeptide peptidase M4 and M36; peptidase M4 thermolysin; SPTR: Zinc metalloprotease (Elastase)-like protein; manually curated; PFAM: Fungalysin/Thermolysin propeptide Motif; Thermolysin metallopeptidase, alpha-helical domain; peptidase family M28; peptidase propeptide and YPEB domain; Thermolysin metallopeptidase, catalytic domain YP_004097836.1 KEGG: cfl:Cfla_0472 hypothetical protein; SPTR: uncharacterized protein; PFAM: anti-sigma-K factor rskA YP_004097837.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR000838: IPR014284; KEGG: kfl:Kfla_4447 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004097838.1 InterPro IPR005754; KEGG: kfl:Kfla_4448 peptidase C60 sortase A and B; PFAM: peptidase C60 sortase A and B; SPTR: peptidase C60 sortase A and B; PFAM: Sortase family; TIGRFAM: LPXTG-site transpeptidase (sortase) family protein YP_004097839.1 KEGG: kfl:Kfla_4449 hypothetical protein; SPTR: uncharacterized protein YP_004097840.1 COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR002937; KEGG: kfl:Kfla_2764 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase YP_004097841.1 COGs: COG1926 phosphoribosyltransferase; InterPro IPR000836; KEGG: art:Arth_3462 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; Dienelactone hydrolase family YP_004097842.1 COGs: COG0136 aspartate-semialdehyde dehydrogenase; InterProIPR000534: IPR012280: IPR012080: IPR000319: IPR 005986; KEGG: kfl:Kfla_2399 aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; PRIAM: aspartate-semialdehyde dehydrogenase; SPTR: aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase, dimerisation domain; semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) YP_004097843.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593; KEGG: kse:Ksed_24860 DNA polymerase III gamma/tau subunit; SMART: ATPase AAA; SPTR: ATPase; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III delta' subunit YP_004097844.1 COGs: COG0125 Thymidylate kinase; InterPro IPR000062: IPR018094: IPR018095; KEGG: kse:Ksed_24870 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_004097845.1 InterPro IPR000073: IPR013595; KEGG: kse:Ksed_24850 alpha/beta hydrolase family protein; PFAM: TAP domain protein; alpha/beta hydrolase fold; SPTR: proteinase ( secreted protein); PFAM: TAP-like protein YP_004097846.1 InterPro IPR000073: IPR013595; KEGG: kse:Ksed_24850 alpha/beta hydrolase family protein; PFAM: TAP domain protein; alpha/beta hydrolase fold; SPTR: alpha/beta hydrolase family protein; PFAM: TAP-like protein YP_004097847.1 InterPro IPR000073: IPR013595; KEGG: sro:Sros_9211 hypothetical protein; PFAM: TAP domain protein; alpha/beta hydrolase fold; SPTR: uncharacterized protein; PFAM: TAP-like protein; alpha/beta hydrolase fold YP_004097848.1 InterPro IPR013538; KEGG: mjl:Mjls_3529 hypothetical protein; PFAM: activator of Hsp90 ATPase 1 family protein; SPTR: activator of Hsp90 ATPase 1 family protein; PFAM: activator of Hsp90 ATPase homolog 1-like protein YP_004097849.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: mjl:Mjls_3530 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family YP_004097850.1 COGs: COG0168 Trk-type K+ transporters membrane components; InterPro IPR003445; KEGG: tcu:Tcur_1710 H(+)-transporting two-sector ATPase; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: H(+)-transporting two-sector ATPase; PFAM: Cation transporter; TIGRFAM: potassium uptake protein, TrkH family YP_004097851.1 COGs: COG0569 K+ transporters NAD-binding component; InterPro IPR003148: IPR006037; KEGG: sen:SACE_2151 potassium uptake protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain YP_004097852.1 COGs: COG0376 catalase (peroxidase I); InterPro IPR002016: IPR000763: IPR019793: IPR019794; KEGG: rha:RHA1_ro05275 catalase; PFAM: Haem peroxidase; SPTR: catalase-peroxidase; TIGRFAM: catalase/peroxidase HPI; manually curated; PFAM: Peroxidase; TIGRFAM: catalase/peroxidase HPI YP_004097853.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753: IPR018376; KEGG: tfu:Tfu_1259 enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase family YP_004097854.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: svi:Svir_08640 acyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme YP_004097855.1 InterPro IPR011701; KEGG: pak:HMPREF0675_5035 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein YP_004097856.1 COGs: COG0474 Cation transport ATPase; InterProIPR008250: IPR005834: IPR018303: IPR001757: IPR 000695; KEGG: nml:Namu_2937 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: ATPase P; TIGRFAM: ATPase P; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004097857.1 COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302: IPR001891; KEGG: nca:Noca_0113 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: malate dehydrogenase (Oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_004097858.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: kfl:Kfla_6862 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: transmembrane transporter; PFAM: Major Facilitator Superfamily YP_004097859.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048: IPR019952; KEGG: rha:RHA1_ro04019 alkanesulfonate monooxygenase; PFAM: Luciferase-like, subgroup; SPTR: uncharacterized protein; TIGRFAM: F420-dependent oxidoreductase; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable F420-dependent oxidoreductase, Rv1855c family YP_004097860.1 COGs: COG1741 Pirin-related protein; InterPro IPR003829: IPR008778: IPR012093; KEGG: sna:Snas_2745 pirin domain-containing protein; PFAM: pirin; SPTR: pirin; PFAM: Pirin C-terminal cupin domain; Pirin YP_004097861.1 COGs: COG2388 acetyltransferase; KEGG: sco:SCO7730 hypothetical protein; SPTR: uncharacterized protein YP_004097862.1 COGs: COG2149 membrane protein; InterPro IPR003807; KEGG: kra:Krad_3719 protein of unknown function DUF202; PFAM: protein of unknown function DUF202; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF YP_004097863.1 InterPro IPR003807: IPR020264; KEGG: sen:SACE_6376 hypothetical protein; PFAM: protein of unknown function DUF202; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF YP_004097864.1 COGs: COG3808 inorganic pyrophosphatase; InterPro IPR004131: IPR000215; KEGG: nml:Namu_0736 membrane-bound proton-translocating pyrophosphatase; PFAM: inorganic H pyrophosphatase; PRIAM: inorganic diphosphatase; SPTR: V-type H(+)-translocating pyrophosphatase; TIGRFAM: V-type H(+)-translocating pyrophosphatase; PFAM: inorganic H+ pyrophosphatase; TIGRFAM: vacuolar-type H(+)-translocating pyrophosphatase YP_004097865.1 COGs: COG0221 inorganic pyrophosphatase; InterPro IPR008162; KEGG: mbt:JTY_3687 inorganic pyrophosphatase; PFAM: inorganic pyrophosphatase; PRIAM: inorganic diphosphatase; SPTR: inorganic pyrophosphatase; PFAM: inorganic pyrophosphatase YP_004097866.1 COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: kra:Krad_0527 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; SPTR: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family YP_004097867.1 KEGG: afw:Anae109_3519 hypothetical protein; SPTR: uncharacterized protein YP_004097868.1 COGs: COG5282 conserved hypothetical protein; InterPro IPR018766; KEGG: kra:Krad_0528 hypothetical protein; PFAM: protein of unknown function DUF2342; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterised conserved protein (DUF2342); TIGRFAM: hydrolase; uncharacterized protein, coenzyme F420 biosynthesis associated YP_004097869.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063: IPR012795; KEGG: tcu:Tcur_4507 tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; SPTR: tRNA(Ile)-lysidine synthetase; TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, N-terminal domain YP_004097870.1 COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836: IPR005904; KEGG: kse:Ksed_24790 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; manually curated; PFAM: phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_004097871.1 COGs: COG3342 conserved hypothetical protein; InterPro IPR010430: IPR014927; KEGG: kse:Ksed_04410 hypothetical protein; PFAM: protein of unknown function DUF1028; peptidoglycan binding; SPTR: Uncharacterized conserved protein; PFAM: peptidoglycan binding domain; Family of unknown function (DUF1028) YP_004097872.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR003959: IPR000642: IPR003593: IPR003960: IPR 005936; KEGG: kra:Krad_0538 ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: microtubule-severing ATPase; SMART: AAA ATPase; SPTR: cell division protein FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004097873.1 COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602: IPR001474: IPR018234; KEGG: ske:Sked_32080 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_004097874.1 COGs: COG0294 dihydropteroate synthase; InterPro IPR000489: IPR006390; KEGG: tbi:Tbis_3445 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: dihydropteroate synthase; SPTR: dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_004097875.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR006157: IPR000550: IPR006156; KEGG: kse:Ksed_24750 dihydroneopterin aldolase/2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; dihydroneopterin aldolase; SPTR: SulD; TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: dihydroneopterin aldolase; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; FolB domain YP_004097876.1 KEGG: ske:Sked_32050 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3180) YP_004097877.1 KEGG: stp:Strop_0985 hypothetical protein; SPTR: uncharacterized protein YP_004097878.1 KEGG: mul:MUL_0582 hypothetical protein; SPTR: Conserved protein YP_004097879.1 COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; InterPro IPR001135: IPR014029; KEGG: sro:Sros_9168 NADH dehydrogenase (quinone); PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase I chain D; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit YP_004097880.1 COGs: COG2372 conserved hypothetical protein homolog of Cu resistance protein CopC; InterPro IPR007348; KEGG: aau:AAur_0407 copper resistance protein CopC; PFAM: copper resistance protein CopC; SPTR: copper resistance protein, CopC family; PFAM: Copper resistance protein CopC YP_004097881.1 COGs: COG1565 conserved hypothetical protein; InterPro IPR003788; KEGG: sgr:SGR_4103 hypothetical protein; PFAM: protein of unknown function DUF185; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1565 YP_004097882.1 COGs: COG5495 conserved hypothetical protein; InterPro IPR019665: IPR018931; KEGG: tcu:Tcur_4488 NADP oxidoreductase coenzyme F420-dependent; PFAM: oxidoreductase/dehydrogenase, Rossmann-like domain; Domain of unknown function DUF2520; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF2520); Rossmann-like domain YP_004097883.1 COGs: COG0414 Panthothenate synthetase; InterPro IPR003721; KEGG: kra:Krad_0575 pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantothenate synthetase; TIGRFAM: pantoate/beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase YP_004097884.1 COGs: COG0853 aspartate 1-decarboxylase; InterPro IPR003190; KEGG: jde:Jden_2095 aspartate 1-decarboxylase; PFAM: aspartate decarboxylase; PRIAM: aspartate 1-decarboxylase; SPTR: aspartate 1-decarboxylase; TIGRFAM: aspartate 1-decarboxylase; PFAM: aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_004097885.1 KEGG: rba:RB9482 hypothetical protein; SPTR: uncharacterized protein YP_004097886.1 COGs: COG0029 aspartate oxidase; InterPro IPR003953: IPR004112: IPR005288; KEGG: tbi:Tbis_3424 L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: domain; FAD binding domain; TIGRFAM: L-aspartate oxidase YP_004097887.1 COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638: IPR004393; KEGG: stp:Strop_4279 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide pyrophophorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase YP_004097888.1 InterPro IPR013216; KEGG: tcu:Tcur_4465 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004097889.1 KEGG: kra:Krad_0608 hypothetical protein; SPTR: uncharacterized protein YP_004097890.1 KEGG: rer:RER_17720 hypothetical protein; SPTR: Hypothetical membrane protein; PFAM: SPW repeat YP_004097891.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593: IPR003439; KEGG: kse:Ksed_22040 ABC-type multidrug transporter ATPase component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter ATPase component; PFAM: ABC transporter YP_004097892.1 COGs: COG0842 ABC-type multidrug transporter permease; InterPro IPR000412: IPR013525; KEGG: nca:Noca_0479 ABC-2 type transporter; PFAM: ABC transporter; SPTR: ABC transporter permease; PFAM: ABC transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_004097893.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: tcu:Tcur_2012 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: DNA-binding protein; PFAM: Ppx/GppA phosphatase family YP_004097894.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: fre:Franean1_6143 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel YP_004097895.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198: IPR020904; KEGG: cmi:CMM_2090 short chain dehydrogenase/oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: short chain dehydrogenase/oxidoreductase; PFAM: short chain dehydrogenase YP_004097896.1 COGs: COG0427 acetyl-CoA hydrolase; KEGG: nca:Noca_1803 acetyl-CoA hydrolase/transferase; SPTR: acetyl-CoA hydrolase/transferase YP_004097897.1 COGs: COG1273 conserved hypothetical protein; InterPro IPR006164: IPR009187; KEGG: nca:Noca_1234 DNA end-binding protein Ku; PFAM: Ku domain protein; SMART: Ku domain protein; SPTR: uncharacterized protein; TIGRFAM: Ku protein; PFAM: Ku70/Ku80 beta-barrel domain; TIGRFAM: Ku protein, prokaryotic YP_004097898.1 COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR014146: IPR016059; KEGG: cfl:Cfla_1903 DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain YP_004097899.1 COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755: IPR014145; KEGG: nca:Noca_1237 ATP dependent DNA ligase; PFAM: DNA primase small subunit; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain protein; TIGRFAM: DNA polymerase LigD, polymerase domain YP_004097900.1 KEGG: bcv:Bcav_0722 hypothetical protein; SPTR: uncharacterized protein; PFAM: Lsr2 YP_004097901.1 KEGG: kse:Ksed_24650 hypothetical protein; SPTR: uncharacterized protein YP_004097902.1 COGs: COG1066 ATP-dependent serine protease; InterPro IPR003593: IPR004504; KEGG: kra:Krad_0603 DNA repair protein RadA; SMART: AAA ATPase; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; PFAM: KaiC; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: DNA repair protein RadA YP_004097903.1 COGs: COG1623 nucleic-acid-binding protein (contains the HHH domain); InterPro IPR003390: IPR018906: IPR000445; KEGG: kra:Krad_0602 DNA integrity scanning protein DisA; PFAM: protein of unknown function DUF147; DNA integrity scanning, DisA, linker region; helix-hairpin-helix motif; SPTR: DNA-binding protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding; DisA bacterial checkpoint controller linker region YP_004097904.1 COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265: IPR003651: IPR004036; KEGG: tcu:Tcur_4471 HhH-GPD family protein; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; SMART: HhH-GPD family protein; iron-sulfur cluster loop; SPTR: adenine glycosylase; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: A/G-specific adenine glycosylase YP_004097905.1 KEGG: gau:GAU_3657 hypothetical protein; SPTR: uncharacterized protein YP_004097906.1 COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: lxx:Lxx21330 N-acetylglutamate synthase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004097907.1 COGs: COG1316 transcriptional regulator; InterPro IPR004474; KEGG: kra:Krad_3901 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004097908.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593: IPR001943: IPR001270: IPR004176: IPR 003959: IPR013093: IPR019489: IPR018368; KEGG: sma:SAV_4697 ATP-dependent Clp protease; PFAM: ATPase AAA; Clp domain protein; ATPase AAA central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: ATPase AAA; SPTR: ATP-dependent Clp protease; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif YP_004097909.1 KEGG: nml:Namu_3541 hypothetical protein; SPTR: uncharacterized protein YP_004097910.1 COGs: COG0590 cytosine/adenosine deaminase; InterPro IPR002125; KEGG: tfu:Tfu_1723 hypothetical protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: cytosine/adenine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004097911.1 COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR013216; KEGG: sma:SAV_3886 hypothetical protein; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase YP_004097912.1 InterPro IPR010872: IPR017517; KEGG: nca:Noca_0119 hypothetical protein; PFAM: protein of unknown function DUF1503; SPTR: uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: uncharacterized Actinobacterial protein TIGR03083 YP_004097913.1 COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: ami:Amir_1081 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; PFAM: Proline dehydrogenase YP_004097914.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455: IPR000304; KEGG: kfl:Kfla_6400 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_004097915.1 InterPro IPR000182; KEGG: bfa:Bfae_14360 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004097916.1 InterPro IPR000182; KEGG: kse:Ksed_24450 acetyltransferase (GNAT) family protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family YP_004097917.1 COGs: COG0569 K+ transporters NAD-binding component; InterPro IPR003148: IPR006037; KEGG: bfa:Bfae_24350 K+ transport system, NAD-binding component; PFAM: TrkA-N domain protein; SPTR: Potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain YP_004097918.1 COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: kra:Krad_0611 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: histone deacetylase; SPTR: acetoin utilization protein; PFAM: histone deacetylase domain YP_004097919.1 COGs: COG0017 aspartyl/asparaginyl-tRNA synthetase; InterPro IPR006195: IPR002312: IPR004365: IPR004364; KEGG: kfl:Kfla_5221 tRNA synthetase class II (D K and N); PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: aspartate--tRNA ligase; SPTR: tRNA synthetase class II (D K and N); PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain YP_004097920.1 InterPro IPR010093; KEGG: kra:Krad_0612 phage transcriptional regulator, AlpA; SPTR: Phage transcriptional regulator, AlpA; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family YP_004097921.1 InterPro IPR013177; KEGG: mcu:HMPREF0573_10552 hypothetical protein; PFAM: protein of unknown function DUF1713; SPTR: uncharacterized protein; PFAM: Mitochondrial domain of unknown function (DUF1713) YP_004097922.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: nca:Noca_0486 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: epimerase; PFAM: NAD dependent epimerase/dehydratase family YP_004097923.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: fre:Franean1_6136 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: uncharacterized protein; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004097924.1 KEGG: kfl:Kfla_6382 hypothetical protein; SPTR: uncharacterized protein YP_004097925.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR007630: IPR014284; KEGG: sma:SAV_4735 ECF subfamily RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, TIGR02952 family YP_004097926.1 KEGG: kfl:Kfla_5632 hypothetical protein; SPTR: uncharacterized protein YP_004097927.1 KEGG: kra:Krad_0034 hypothetical protein; SPTR: uncharacterized protein YP_004097928.1 InterPro IPR008554; KEGG: nca:Noca_0492 glutaredoxin 2; PFAM: glutaredoxin 2; SPTR: glutaredoxin 2; PFAM: glutaredoxin-like domain (DUF836) YP_004097929.1 COGs: COG2344 AT-rich DNA-binding protein; InterPro IPR009718: IPR003781; KEGG: sco:SCO3320 redox-sensing transcriptional repressor REX; PFAM: CoA-binding protein; Rex DNA-binding domain protein; SPTR: Redox-sensing transcriptional repressor Rex; PFAM: CoA binding domain; DNA-binding protein N-terminus YP_004097930.1 COGs: COG0373 glutamyl-tRNA reductase; InterPro IPR000343: IPR015895: IPR006151: IPR015896; KEGG: kse:Ksed_24410 glutamyl-tRNA reductase; PFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase-like; shikimate/quinate 5-dehydrogenase; PRIAM: glutamyl-tRNA reductase; SPTR: glutamyl-tRNA reductase; TIGRFAM: glutamyl-tRNA reductase; PFAM: shikimate / quinate 5-dehydrogenase; glutamyl-tRNAGlu reductase, N-terminal domain; glutamyl-tRNAGlu reductase, dimerisation domain; TIGRFAM: glutamyl-tRNA reductase YP_004097931.1 COGs: COG0181 porphobilinogen deaminase; InterPro IPR000860; KEGG: kfl:Kfla_6375 porphobilinogen deaminase; PFAM: porphobilinogen deaminase; SPTR: porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: porphobilinogen deaminase, C-terminal domain; porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase YP_004097932.1 COGs: COG1587 uroporphyrinogen-III synthase; InterPro IPR000878: IPR003754: IPR003043; KEGG: kra:Krad_0619 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrinogen III synthase HEM4; SPTR: uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; uroporphyrinogen-III synthase HemD YP_004097933.1 COGs: COG0113 delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: mpa:MAP4005 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: porphobilinogen synthase; SPTR: delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase YP_004097934.1 InterPro IPR000835; KEGG: tcu:Tcur_0136 transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: transcriptional regulator; PFAM: MarR family YP_004097935.1 COGs: COG0001 glutamate-1-semialdehyde aminotransferase; InterPro IPR005814: IPR004639; KEGG: kra:Krad_0626 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: glutamate-1-semialdehyde aminotransferase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase YP_004097936.1 COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: tpr:Tpau_0688 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase; PFAM: phosphoglycerate mutase family YP_004097937.1 InterPro IPR017909: IPR017936: IPR013740; KEGG: kse:Ksed_24350 thiol-disulfide isomerase-like thioredoxin; PFAM: Redoxin domain protein; SPTR: uncharacterized protein; PFAM: Redoxin YP_004097938.1 COGs: COG0785 cytochrome C biogenesis protein; InterPro IPR003834; KEGG: kse:Ksed_24340 cytochrome C biogenesis protein; PFAM: cytochrome C biogenesis protein transmembrane region; SPTR: cytochrome biogenesis related protein; PFAM: cytochrome C biogenesis protein transmembrane region YP_004097939.1 COGs: COG1333 ResB protein required for cytochrome C biosynthesis; KEGG: kra:Krad_0630 ResB family protein; SPTR: Conserved protein, c-type cytochrome biogenesis protein; PFAM: ResB-like family YP_004097940.1 COGs: COG0755 ABC-type transporter involved in cytochrome C biogenesis permease; InterPro IPR002541: IPR017562; KEGG: kra:Krad_0631 cytochrome C assembly protein; PFAM: cytochrome C assembly protein; SPTR: cytochrome C assembly protein; TIGRFAM: cytochrome C biogenesis protein CcsB; PFAM: cytochrome C assembly protein; TIGRFAM: cytochrome C biogenesis protein CcsB YP_004097941.1 KEGG: kra:Krad_0632 hypothetical protein; SPTR: uncharacterized protein YP_004097942.1 COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537: IPR004657; KEGG: xce:Xcel_0450 1,4-dihydroxy-2-naphthoateoctaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR:1,4-dihydroxy-2-naphthoateoctaprenyltransferas e; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_004097943.1 KEGG: rmu:RMDY18_03610 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; SPTR:phosphatidylserine/ phosphatidylglycerophosphate/ cardiolipin synthase YP_004097944.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: sen:SACE_6916 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: MenE; PFAM: AMP-binding enzyme YP_004097945.1 InterPro IPR011701; KEGG: kfl:Kfla_5920 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: integral membrane protein; PFAM: Major Facilitator Superfamily YP_004097946.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: cfl:Cfla_0652 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004097947.1 InterPro IPR019825; KEGG: xce:Xcel_2744 hypothetical protein; SPTR: uncharacterized protein YP_004097948.1 COGs: COG0447 dihydroxynaphthoic acid synthase; InterPro IPR001753: IPR010198: IPR018376; KEGG: cef:CE0475 naphthoate synthase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: naphthoate synthase; TIGRFAM: naphthoate synthase; PFAM: enoyl-CoA hydratase/isomerase family; TIGRFAM: naphthoate synthase (dihydroxynaphthoic acid synthetase) YP_004097949.1 InterPro IPR000086; KEGG: cfl:Cfla_2802 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004097950.1 KEGG: nca:Noca_0375 hypothetical protein; SPTR: uncharacterized protein YP_004097951.1 COGs: COG2038 NaMN:DMB phosphoribosyltransferase; InterPro IPR017846: IPR003200; KEGG: nml:Namu_0165 nicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; PRIAM: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; SPTR: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM:nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_004097952.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013342; KEGG: aau:AAur_3115 O-succinylbenzoic acid (OSB) synthetase; PFAM: mandelate racemase/muconate lactonizing protein; SPTR: O-succinylbenzoate-CoA synthase; PFAM: mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoic acid (OSB) synthetase YP_004097953.1 COGs: COG3246 conserved hypothetical protein; InterPro IPR008567; KEGG: sen:SACE_3693 hypothetical protein; PFAM: protein of unknown function DUF849; SPTR: uncharacterized protein; PFAM: Prokaryotic protein of unknown function (DUF849) YP_004097954.1 COGs: COG1165 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase; InterPro IPR004433: IPR012001; KEGG: nca:Noca_0510 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohex ene-1-carboxylic-acidsynthase; SPTR:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexe ne-1-carboxylatesynthase; TIGRFAM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; PFAM: thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase YP_004097955.1 COGs: COG1169 Isochorismate synthase; InterPro IPR015890: IPR004561; KEGG: kfl:Kfla_6301 isochorismate synthase; PFAM: chorismate binding-like; SPTR: Isochorismate synthase; TIGRFAM: isochorismate synthase; PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases YP_004097956.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR004033; KEGG: cfl:Cfla_2718 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; SPTR: Menaquinone biosynthesis methyltransferase ubiE; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: ubiE/COQ5 methyltransferase family; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases YP_004097957.1 COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); InterPro IPR000440; KEGG: tcu:Tcur_4418 NADH-ubiquinone/plastoquinone oxidoreductase chain 3; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; SPTR: NADH-quinone oxidoreductase subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_004097958.1 COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; InterPro IPR006137: IPR006138; KEGG: cai:Caci_7690 NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase subunit beta; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit YP_004097959.1 COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268: IPR010218; KEGG: cfl:Cfla_2714 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH dehydrogenase subunit C; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C YP_004097960.1 COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; InterPro IPR001135: IPR010219: IPR014029; KEGG: sma:SAV_4840 NADH dehydrogenase subunit D; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase delta subunit; TIGRFAM: NADH dehydrogenase I, D subunit; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; TIGRFAM: NADH dehydrogenase I, D subunit YP_004097961.1 COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: jde:Jden_0543 NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: ATP synthase subunit E; TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit YP_004097962.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538: IPR019554: IPR019575: IPR011537: IPR 001949; KEGG: cfl:Cfla_2711 NADH-quinone oxidoreductase, F subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, F subunit; TIGRFAM: NADH-quinone oxidoreductase, F subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; TIGRFAM: NADH-quinone oxidoreductase, F subunit YP_004097963.1 COGs: COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); InterProIPR001041: IPR019574: IPR006963: IPR006656: IPR 006657: IPR010228: IPR000283; KEGG: tcu:Tcur_4412 NADH-quinone oxidoreductase, chain G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: NADH-quinone oxidoreductase; TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: NADH-quinone oxidoreductase, chain G YP_004097964.1 COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR001694: IPR018086; KEGG: cfl:Cfla_2709 NADH dehydrogenase (quinone); PFAM: respiratory-chain NADH dehydrogenase subunit 1; SPTR: NADH dehydrogenase subunit H; PFAM: NADH dehydrogenase YP_004097965.1 COGs: COG1143 formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017896: IPR010226: IPR017900; KEGG: bcv:Bcav_3221 NADH-quinone oxidoreductase, chain I; SPTR: NuoI, NADH dehydrogenase subunit; TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S binding domain; TIGRFAM: NADH-quinone oxidoreductase, chain I YP_004097966.1 COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: cfl:Cfla_2707 NADH-ubiquinone/plastoquinone oxidoreductase chain 6; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; SPTR: NADH dehydrogenase subunit J; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YP_004097967.1 COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); InterPro IPR001133; KEGG: ace:Acel_0277 NADH dehydrogenase subunit K; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: NADH dehydrogenase kappa subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_004097968.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter Mnhsubunit alpha; InterProIPR003916: IPR018393: IPR001516: IPR001750: IPR 003945; KEGG: bcv:Bcav_3218 NADH dehydrogenase subunit L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: NADH dehydrogenase subunit L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L YP_004097969.1 COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR001750: IPR010227; KEGG: cfl:Cfla_2704 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH dehydrogenase subunit M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M YP_004097970.1 COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); InterPro IPR001750: IPR010096; KEGG: mjl:Mjls_1534 NADH dehydrogenase subunit N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH dehydrogenase subunit N; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N YP_004097971.1 COGs: COG0142 geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: kse:Ksed_21410 geranylgeranyl pyrophosphate synthase; PFAM: polyprenyl synthetase; SPTR: polyprenyl diphosphate synthase; PFAM: polyprenyl synthetase YP_004097972.1 COGs: COG3616 amino acid aldolase or racemase; InterPro IPR001608; KEGG: sen:SACE_0064 amino acid aldolase or racemase-like; PFAM: alanine racemase domain protein; SPTR: Amino acid aldolase or racemase family protein; PFAM: alanine racemase, N-terminal domain YP_004097973.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR007173: IPR010032; KEGG: kfl:Kfla_1866 FAD-linked oxidoreductase; PFAM: D-arabinono-14-lactone oxidase; FAD linked oxidase domain protein; SPTR: FAD-linked oxidoreductase; TIGRFAM: FAD-linked oxidoreductase; PFAM: D-arabinono-1,4-lactone oxidase; FAD binding domain; TIGRFAM: FAD-linked oxidoreductase YP_004097974.1 COGs: COG0114 Fumarase; InterPro IPR000362: IPR018951: IPR020557; KEGG: kfl:Kfla_5598 fumarate lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: fumarate lyase; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: fumarate hydratase, class II YP_004097975.1 COGs: COG0282 acetate kinase; InterPro IPR000890: IPR004372; KEGG: kfl:Kfla_4452 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: acetate kinase; TIGRFAM: acetate kinase; PFAM: acetokinase family; TIGRFAM: acetate kinase YP_004097976.1 COGs: COG0280 phosphotransacetylase; InterPro IPR010766: IPR002505: IPR016475: IPR004614; KEGG: kfl:Kfla_4453 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; DRTGG domain protein; PRIAM: phosphate acetyltransferase; SPTR: phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: DRTGG domain; phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase YP_004097977.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter EmrB/QacA subfamily; TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter EmrB/QacA subfamily YP_004097978.1 COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein YP_004097979.1 COGs: COG1013 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit beta; InterPro IPR011766; KEGG: sen:SACE_3926 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Ferrodoxin oxidoreductase beta subunit; PFAM: thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004097980.1 COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit alpha; InterPro IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: oxidoreductase; PFAM: domain; pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, subunit alpha YP_004097981.1 COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); InterPro IPR000440; KEGG: tbi:Tbis_0315 NADH-ubiquinone/plastoquinone oxidoreductase subunit 3; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; SPTR: NADH-quinone oxidoreductase subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_004097982.1 COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; InterPro IPR006137: IPR006138; KEGG: sgr:SGR_2924 NADH dehydrogenase chain B; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase I chain B; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit YP_004097983.1 COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: tcu:Tcur_4386 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH dehydrogenase; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit YP_004097984.1 COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR001694; KEGG: kfl:Kfla_6242 NADH dehydrogenase (quinone); PFAM: respiratory-chain NADH dehydrogenase subunit 1; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase I chain H; PFAM: NADH dehydrogenase YP_004097985.1 COGs: COG1143 formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017896: IPR010226: IPR017900; KEGG: cai:Caci_0849 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: NADH dehydrogenase subunit; PFAM: 4Fe-4S binding domain YP_004097986.1 COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: sro:Sros_0670 NADH-ubiquinone oxidoreductase protein, chain J; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; SPTR: uncharacterized protein; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YP_004097987.1 COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); InterPro IPR001133; KEGG: kfl:Kfla_6230 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_004097988.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter Mnhsubunit alpha; InterPro IPR003916: IPR001750; KEGG: tcu:Tcur_4380 proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH dehydrogenase subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus YP_004097989.1 COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR001750: IPR010227; KEGG: sgr:SGR_2917 NADH dehydrogenase chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH dehydrogenase I chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M YP_004097990.1 COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); InterPro IPR001750; KEGG: tcu:Tcur_4378 proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: uncharacterized protein; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N YP_004097991.1 COGs: COG2382 Enterochelin esterase; InterPro IPR000801; KEGG: amd:AMED_4204 enterochelin esterase and related enzyme; PFAM: esterase; SPTR: esterase; PFAM: esterase YP_004097992.1 KEGG: nca:Noca_3649 hypothetical protein; SPTR: uncharacterized protein YP_004097993.1 COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: ach:Achl_2779 heat shock protein HtpX; PFAM: peptidase M48 Ste24p; SPTR: heat shock protein HtpX; PFAM: peptidase family M48 YP_004097994.1 COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR012778; KEGG: kse:Ksed_21360 aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; SPTR: aminopeptidase; TIGRFAM: aminopeptidase N; PFAM: peptidase family M1; Domain of unknown function (DUF3358); TIGRFAM: aminopeptidase N, Streptomyces lividans type YP_004097995.1 InterPro IPR004360; KEGG: rop:ROP_60000 hypothetical protein; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004097996.1 KEGG: xce:Xcel_1055 oxidoreductase; SPTR: oxidoreductase; PFAM: short chain dehydrogenase YP_004097997.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940: IPR001254; KEGG: bcv:Bcav_3234 2-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Trypsin-like serine protease; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF) YP_004097998.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: kse:Ksed_21630 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: two-component system sensor kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004097999.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867: IPR005829; KEGG: kra:Krad_3620 transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator of two-component system; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004098000.1 KEGG: rhi:NGR_c22260 hypothetical protein; SPTR: uncharacterized protein YP_004098001.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: stp:Strop_0454 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter YP_004098002.1 KEGG: ace:Acel_1415 hypothetical protein; SPTR: uncharacterized protein YP_004098003.1 KEGG: ajs:Ajs_1031 PepSY-associated TM helix domain-containing protein; SPTR: Major facilitator superfamily MFS_1 YP_004098004.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001: IPR001650: IPR014021: IPR006935; KEGG: ske:Sked_31430 DNA/RNA helicase, superfamily II; PFAM: helicase; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; type III restriction enzyme, res subunit YP_004098005.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: kse:Ksed_21580 hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; SPTR: hydroxymethylglutaryl-CoA lyase; PFAM: HMGL-like YP_004098006.1 KEGG: kra:Krad_3610 hypothetical protein; SPTR: uncharacterized protein YP_004098007.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: fal:FRAAL2426 aldose-1-epimerase; PFAM: aldose 1-epimerase; SPTR: galactose mutarotase; PFAM: aldose 1-epimerase YP_004098008.1 COGs: COG1278 Cold shock protein; InterPro IPR011129: IPR002059; KEGG: kse:Ksed_24110 cold-shock DNA-binding protein family; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: Cold shock protein; PFAM: 'Cold-shock' DNA-binding domain YP_004098009.1 KEGG: ske:Sked_31380 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3027) YP_004098010.1 KEGG: tcu:Tcur_0821 hypothetical protein; SPTR: uncharacterized protein YP_004098011.1 COGs: COG2252 Permease; InterPro IPR006043; KEGG: kfl:Kfla_5917 xanthine/uracil/vitamin C permease; PFAM: xanthine/uracil/vitamin C permease; SPTR: xanthine/uracil/vitamin C permease; PFAM: Permease family YP_004098012.1 InterPro IPR000835; KEGG: cms:CMS_0691 MarR-family protein; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR family transcriptional regulator; PFAM: MarR family YP_004098013.1 InterPro IPR011701; KEGG: kfl:Kfla_5912 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: integral membrane efflux protein; PFAM: Bacterial protein of unknown function (DUF894) YP_004098014.1 PFAM: protein of unknown function (DUF2964) YP_004098015.1 KEGG: rme:Rmet_1008 hypothetical protein; SPTR: uncharacterized protein YP_004098016.1 COGs: COG2951 membrane-bound lytic murein transglycosylase B; KEGG: nca:Noca_0498 secreted protein; SPTR: secreted protein YP_004098017.1 COGs: COG1932 phosphoserine aminotransferase; InterPro IPR000192: IPR006272; KEGG: kfl:Kfla_5896 phosphoserine aminotransferase; PFAM: aminotransferase class V; SPTR: phosphoserine aminotransferase; TIGRFAM: phosphoserine aminotransferase; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase, Methanosarcina type; phosphoserine aminotransferase YP_004098018.1 KEGG: gob:Gobs_0955 hypothetical protein; SPTR: uncharacterized protein YP_004098019.1 COGs: COG0372 citrate synthase; InterPro IPR002020: IPR019810; KEGG: sma:SAV_3859 citrate synthase 2; PFAM: citrate synthase; PRIAM: citrate (Si)-synthase; SPTR: citrate (Si)-synthase; PFAM: citrate synthase YP_004098020.1 InterPro IPR001646; KEGG: ske:Sked_35000 uncharacterized low-complexity protein; PFAM: pentapeptide repeat protein; SPTR: Uncharacterized low-complexity protein YP_004098021.1 KEGG: ajs:Ajs_3323 hypothetical protein; SPTR: uncharacterized protein YP_004098022.1 KEGG: kfl:Kfla_4576 hypothetical protein; SPTR: uncharacterized protein YP_004098023.1 COGs: COG0259 pyridoxamine-phosphate oxidase; InterPro IPR011576: IPR019576: IPR019740; KEGG: kse:Ksed_24050 pyridoxamine-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; pyridoxine 5'-phosphate oxidase dimerisation-like; PRIAM: pyridoxal 5'-phosphate synthase; SPTR: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase; pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; TIGRFAM: pyridoxamine-phosphate oxidase YP_004098024.1 KEGG: scl:sce1155 hypothetical protein; SPTR: membrane protein YP_004098025.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: kfl:Kfla_6159 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Probable transporter; PFAM: Major Facilitator Superfamily YP_004098026.1 COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001808: IPR001367: IPR007167; KEGG: kse:Ksed_24030 Mn-dependent transcriptional regulator; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; regulatory protein Crp; SPTR: Iron-dependent repressor, DxtR metalloregulatory family protein; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_004098027.1 COGs: COG0791 cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: kra:Krad_4554 NLP/P60 protein; PFAM: NLP/P60 protein; SPTR: protein containing cell-wall hydrolase domain; PFAM: NlpC/P60 family YP_004098028.1 COGs: COG2761 dithiol-disulfide isomerase involved in polyketide biosynthesis; InterPro IPR001853; KEGG: tfu:Tfu_1267 FrnE protein; PFAM: DSBA oxidoreductase; SPTR: FrnE protein; PFAM: DSBA-like thioredoxin domain YP_004098029.1 InterPro IPR002645: IPR003658; KEGG: svi:Svir_34950 anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PFAM: sulfate transporter/antisigma-factor antagonist STAS; SPTR: anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor); TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_004098030.1 COGs: COG2208 serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR007895: IPR010822: IPR003594; KEGG: gob:Gobs_0116 multi-sensor signal transduction histidine kinase; PFAM: stage II sporulation protein E; MASE1 domain protein; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: stage II sporulation protein E (SpoIIE); MASE1 YP_004098031.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: mlu:Mlut_18370 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004098032.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: rha:RHA1_ro11203 response regulator, two-component system; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator, two-component system; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004098033.1 InterPro IPR018649; KEGG: rop:ROP_pROB01-02360 hypothetical membrane protein; PFAM: protein of unknown function DUF2078, membrane; SPTR: Hypothetical membrane protein; PFAM: Predicted membrane protein (DUF2078) YP_004098034.1 COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR001757: IPR008250: IPR005834: IPR 006403: IPR006416: IPR018303; KEGG: rha:RHA1_ro11210 copper-exporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: cation-transporting ATPase; TIGRFAM: ATPase P; copper-translocating P-type ATPase; ATPase P; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase P YP_004098035.1 InterPro IPR017871; KEGG: cfl:Cfla_2448 hypothetical protein; SPTR: uncharacterized protein YP_004098036.1 KEGG: ske:Sked_28360 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004098037.1 KEGG: sco:SCO7373 hypothetical protein; SPTR: uncharacterized protein SCO7373 YP_004098038.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006963: IPR006656: IPR006657: IPR006655; KEGG: art:Arth_4046 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain YP_004098039.1 COGs: COG5607 conserved hypothetical protein; InterPro IPR008172: IPR007899; KEGG: kfl:Kfla_0605 CHAD domain containing protein; PFAM: CHAD domain containing protein; adenylate cyclase; SPTR: CHAD domain containing protein; PFAM: CYTH domain; CHAD domain YP_004098040.1 KEGG: ahe:Arch_1155 hypothetical protein; SPTR: uncharacterized protein; PFAM: dinitrogenase iron-molybdenum cofactor YP_004098041.1 COGs: COG1010 precorrin-3B methylase; InterPro IPR000878: IPR006364: IPR006363; KEGG: nda:Ndas_1624 precorrin-3B C17-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase YP_004098042.1 COGs: COG2082 precorrin isomerase; InterPro IPR003722; KEGG: tfu:Tfu_0317 precorrin-8X methylmutase; PFAM: precorrin-8X methylmutase CbiC/CobH; PRIAM: precorrin-8X methylmutase; SPTR: precorrin-8X methylmutase; PFAM: precorrin-8X methylmutase YP_004098043.1 InterPro IPR011576: IPR019920; KEGG: nca:Noca_0878 pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; TIGRFAM: F420-dependent enzyme; PFAM: pyridoxamine 5'-phosphate oxidase; TIGRFAM: PPOX class probable F420-dependent enzyme YP_004098044.1 KEGG: amr:AM1_5947 plasmid maintenance system killer protein, SPTR: Plasmid maintenance system killer protein YP_004098045.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: sco:SCO3951 hypothetical protein; PFAM: Luciferase-like, subgroup; SPTR: Luciferase protein; PFAM: Luciferase-like monooxygenase YP_004098046.1 KEGG: lch:Lcho_0715 hypothetical protein; SPTR: integron gene cassette protein YP_004098047.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: rlg:Rleg_6246 methyltransferase type 12; PFAM: methyltransferase type 11; SPTR: methyltransferase type 12; PFAM: methyltransferase domain YP_004098048.1 KEGG: nca:Noca_2900 hypothetical protein; SPTR: uncharacterized protein YP_004098049.1 KEGG: nca:Noca_4727 hypothetical protein; SPTR: uncharacterized protein YP_004098050.1 KEGG: nca:Noca_4726 hypothetical protein; SPTR: uncharacterized protein YP_004098051.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nca:Noca_4725 phage integrase; PFAM: integrase; SPTR: Phage integrase; PFAM: Phage integrase family YP_004098052.1 COGs: COG3547 transposase and inactivated derivatives; InterPro IPR003346; KEGG: mgi:Mflv_0689 transposase IS116/IS110/IS902 family protein; PFAM: transposase IS116/IS110/IS902 family protein; SPTR: IS110 family transposase; PFAM: transposase IS116/IS110/IS902 family; transposase YP_004098053.1 KEGG: fra:Francci3_0166 hypothetical protein; SPTR: uncharacterized protein YP_004098054.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: mlu:Mlut_14300 transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: transposase; PFAM: transposase YP_004098055.1 InterPro IPR003346; KEGG: mva:Mvan_4882 transposase IS116/IS110/IS902 family protein; PFAM: transposase IS116/IS110/IS902 family protein; SPTR: transposase IS116/IS110/IS902 family protein; PFAM: transposase IS116/IS110/IS902 family; transposase YP_004098056.1 COGs: COG0155 Sulfite reductase subunit beta (hemoprotein); KEGG: kfl:Kfla_5082 precorrin-3B synthase; SPTR: precorrin-3B synthase YP_004098057.1 COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672: IPR011953; KEGG: nml:Namu_0145 cobaltochelatase subunit CobN; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: Cobaltochelatase; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/Magnesium Chelatase; TIGRFAM: cobaltochelatase, CobN subunit YP_004098058.1 COGs: COG2243 precorrin-2 methylase; InterPro IPR000878: IPR012797; KEGG: mex:Mext_3385 precorrin 6A synthase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: precorrin-6A synthase (deacetylating); SPTR: uncharacterized protein; TIGRFAM: precorrin-6A synthase (deacetylating); PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-6A synthase (deacetylating) YP_004098059.1 COGs: COG1492 Cobyric acid synthase; InterPro IPR017929: IPR004459: IPR011698; KEGG: nml:Namu_0138 cobyric acid synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: Cobyric acid synthase; TIGRFAM: cobyric acid synthase CobQ; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyric acid synthase CobQ YP_004098060.1 COGs: COG2099 precorrin-6x reductase; InterPro IPR003723; KEGG: svi:Svir_17710 precorrin-6A reductase; PFAM: precorrin-6x reductase CbiJ/CobK; PRIAM: precorrin-6A reductase; SPTR: precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase; PFAM: precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase YP_004098061.1 COGs: COG0007 uroporphyrinogen-III methylase; InterPro IPR000878: IPR006366; KEGG: nml:Namu_0162 uroporphyrin-III C-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: uroporphyrin-III C-methyltransferase YP_004098062.1 COGs: COG1797 cobyrinic acid a c-diamide synthase; InterProIPR017929: IPR004484: IPR011698: IPR004839: IPR 004838; KEGG: nml:Namu_0161 cobyrinic acid a,c-diamide synthase; PFAM: aminotransferase class I and II; CobB/CobQ domain protein glutamine amidotransferase; SPTR: cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; Aminotransferase class I and II; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; cobyrinic acid a,c-diamide synthase YP_004098063.1 COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: svi:Svir_17750 cob(I)yrinic acid a,c-diamide adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase YP_004098064.1 COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593: IPR002035: IPR011704; KEGG: nml:Namu_0159 magnesium chelatase; PFAM: von Willebrand factor A; ATPase associated with various cellular activities AAA_5; PRIAM: Magnesium chelatase; SMART: von Willebrand factor A; ATPase AAA; SPTR: Magnesium chelatase; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor A domain YP_004098065.1 COGs: COG2242 precorrin-6B methylase 2; InterPro IPR000878: IPR006365: IPR012818: IPR014008; KEGG: nml:Namu_0158 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; manually curated; PFAM: methyltransferase small domain; Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit YP_004098066.1 COGs: COG2875 precorrin-4 methylase; InterPro IPR000878: IPR003043; KEGG: tfu:Tfu_0315 precorrin-4 C11-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-4 C11-methyltransferase YP_004098067.1 COGs: COG0310 ABC-type Co2+ transporter permease component; InterPro IPR002751: IPR018024; KEGG: gob:Gobs_0543 cobalamin biosynthesis protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin biosynthesis protein CbiM; TIGRFAM: cobalamin biosynthesis protein CbiM; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM YP_004098068.1 COGs: COG1930 ABC-type cobalt transporter periplasmic component; InterPro IPR003705; KEGG: ami:Amir_3590 cobalt transporter CbiN; PFAM: Cobalt transporter CbiN; SPTR: Cobalt transporter CbiN; PFAM: Cobalt transporter component CbiN; TIGRFAM: cobalt transporter YP_004098069.1 COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339: IPR012809; KEGG: gob:Gobs_0541 cobalt ABC transporter inner membrane subunit CbiQ; PFAM: cobalt transporter; SPTR: Cobalt ABC transporter inner membrane subunit CbiQ; TIGRFAM: cobalt ABC transporter inner membrane subunit CbiQ; PFAM: Cobalt transporter; TIGRFAM: cobalt ABC transporter permease CbiQ YP_004098070.1 COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR003593: IPR003439: IPR005876: IPR017871; KEGG: gob:Gobs_0540 cobalt ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: Cobalt ABC transporter ATPase; TIGRFAM: cobalt ABC transporter ATPase; PFAM: ABC transporter; TIGRFAM: cobalt transporter ATP-binding subunit YP_004098071.1 COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: kse:Ksed_04090 hypothetical protein; PFAM: protein of unknown function DUF162; SPTR: Uncharacterized conserved protein; PFAM: Uncharacterised ACR, YkgG family COG1556 YP_004098072.1 COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741: IPR004452: IPR017900; KEGG: kse:Ksed_04080 (4Fe-4S) cluster-containing protein; PFAM: protein of unknown function DUF162; SPTR: iron-sulfur protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: Domain of unknown function (DUF3390); Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein YP_004098073.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR019758; KEGG: mva:Mvan_2709 hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: uncharacterized protein; PFAM: Cysteine-rich domain YP_004098074.1 COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: gbr:Gbro_2897 L-lactate transport; PFAM: L-lactate permease; SPTR: L-lactate transport; TIGRFAM: L-lactate transport; PFAM: L-lactate permease; TIGRFAM: L-lactate transport YP_004098075.1 COGs: COG2186 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sen:SACE_3508 GntR family transcriptional regulator; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004098076.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mva:Mvan_3225 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004098077.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550; KEGG: gob:Gobs_2950 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: uncharacterized protein; PFAM: CBS domain; Domain of unknown function DUF21 YP_004098078.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550: IPR005170; KEGG: ske:Sked_05880 CBS domain-containing protein; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SPTR: CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21; transporter associated domain YP_004098079.1 COGs: COG1540 conserved hypothetical protein; InterPro IPR005501; KEGG: gob:Gobs_2198 LamB/YcsF family protein; PFAM: LamB/YcsF family protein; SPTR: LamB/YcsF family protein; PFAM: LamB/YcsF family YP_004098080.1 COGs: COG2049 allophanate hydrolase subunit 1; InterPro IPR003833: IPR010016; KEGG: svi:Svir_06200 conserved hypothetical protein TIGR00370; PFAM: allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 1; SPTR: uncharacterized protein; PFAM: allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370 YP_004098081.1 COGs: COG1984 allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: kfl:Kfla_6553 urea amidolyase; PFAM: allophanate hydrolase subunit 2; SMART: allophanate hydrolase subunit 2; SPTR: urea amidolyase; TIGRFAM: urea amidolyase; PFAM: allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain YP_004098082.1 COGs: COG0372 citrate synthase; InterPro IPR002020: IPR010953: IPR019810; KEGG: nml:Namu_4703 citrate synthase I; PFAM: citrate synthase; PRIAM: citrate (Si)-synthase; SPTR: citrate synthase; TIGRFAM: citrate synthase I; PFAM: citrate synthase; TIGRFAM: citrate synthase I (hexameric type) YP_004098083.1 COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: nca:Noca_1837 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase YP_004098084.1 COGs: COG2225 malate synthase; InterPro IPR011076: IPR006252: IPR019830; KEGG: kfl:Kfla_0722 malate synthase A; PFAM: malate synthase family protein; PRIAM: malate synthase; SPTR: malate synthase; TIGRFAM: malate synthase A; PFAM: malate synthase; TIGRFAM: malate synthase A YP_004098085.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR004113; KEGG: sen:SACE_6366 glycolate oxidase subunit; PFAM: FAD linked oxidase; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: glycolate oxidase subunit; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase subunit GlcD YP_004098086.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR004113; KEGG: tcu:Tcur_3272 FAD linked oxidase domain protein; PFAM: FAD linked oxidase; SPTR: FAD linked oxidase; PFAM: FAD binding domain YP_004098087.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR017896: IPR004017: IPR012257: IPR017900; KEGG: sen:SACE_6364 glycolate oxidase iron-sulfur subunit; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: glycolate oxidase iron-sulfur subunit; PFAM: Cysteine-rich domain YP_004098088.1 COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: msm:MSMEG_6826 L-lactate permease; PFAM: L-lactate permease; SPTR: L-lactate permease; TIGRFAM: L-lactate transport; PFAM: L-lactate permease; TIGRFAM: L-lactate transport YP_004098089.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: tfu:Tfu_0849 regulatory proteins, IclR; PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Regulatory proteins, IclR; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004098090.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: stp:Strop_1595 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: ATP-binding region, ATPase domain protein domain protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004098091.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: stp:Strop_1594 response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004098092.1 KEGG: stp:Strop_1593 hypothetical protein; SPTR: uncharacterized protein YP_004098093.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: sro:Sros_3425 ABC transporter related protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004098094.1 InterPro IPR002052; KEGG: sna:Snas_4838 hypothetical protein; SPTR: uncharacterized protein YP_004098095.1 COGs: COG0392 integral membrane protein; InterPro IPR005829; KEGG: tbi:Tbis_3323 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein YP_004098096.1 InterPro IPR001647; KEGG: mjl:Mjls_5623 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family YP_004098097.1 COGs: COG2124 cytochrome P450; InterPro IPR002397: IPR017973: IPR001128: IPR017972; KEGG: ach:Achl_0767 cytochrome P450; PFAM: cytochrome P450; SPTR: cytochrome P450 hydroxylase; PFAM: cytochrome P450 YP_004098098.1 InterPro IPR017896; KEGG: ach:Achl_0766 hypothetical protein; SPTR: Predicted protein; PFAM: protein of unknown function (DUF1271) YP_004098099.1 COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027: IPR000103; KEGG: ach:Achl_0765 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Ferredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004098100.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: scl:sce0177 LysR family transcriptional regulator; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: HTH-type transcriptional regulator syrM; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_004098101.1 InterPro IPR001647; KEGG: ach:Achl_0764 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004098102.1 InterPro IPR011701; KEGG: ach:Achl_0768 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004098103.1 COGs: COG1735 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR001559; KEGG: ach:Achl_0769 aryldialkylphosphatase; PFAM: aryldialkylphosphatase; SPTR: Predicted protein; PFAM: phosphotriesterase family YP_004098104.1 COGs: COG1735 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR001559; KEGG: ach:Achl_0770 aryldialkylphosphatase; PFAM: aryldialkylphosphatase; SPTR: Parathion hydrolase; PFAM: phosphotriesterase family YP_004098105.1 COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR003042: IPR002938; KEGG: ach:Achl_0771 monooxygenase FAD-binding; PFAM: monooxygenase FAD-binding; SPTR: Predicted protein; PFAM: FAD binding domain YP_004098106.1 COGs: COG0657 esterase/lipase; InterPro IPR002168; KEGG: ach:Achl_0772 alpha/beta hydrolase; SPTR: esterase/lipase; PFAM: alpha/beta hydrolase fold YP_004098107.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: ach:Achl_0773 beta-lactamase; SPTR: Predicted protein; PFAM: metallo-beta-lactamase superfamily YP_004098108.1 COGs: COG2936 acyl esterase; InterPro IPR013736: IPR005674; KEGG: ach:Achl_0774 X-Pro dipeptidyl-peptidase domain protein; PFAM: X-Pro dipeptidyl-peptidase domain protein; SPTR: X-Pro dipeptidyl-peptidase domain protein; TIGRFAM: hydrolase CocE/NonD family protein; PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: hydrolase, CocE/NonD family YP_004098109.1 COGs: COG0183 acetyl-CoA acetyltransferase; InterPro IPR020616; KEGG: scb:SCAB_6631 acyl-CoA thiolase; PFAM: thiolase-like; SPTR: acyl-CoA thiolase; PFAM: thiolase, N-terminal domain YP_004098110.1 COGs: COG1788 acyl CoA:acetate/3-ketoacid CoA transferase subunit alpha; InterPro IPR004165: IPR012792: IPR004163; KEGG: scb:SCAB_6621 3-oxoadipate CoA-transferase subunit A; PFAM: coenzyme A transferase; PRIAM: 3-oxoadipate CoA-transferase; SPTR: 3-oxoadipate CoA-transferase subunit A; TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha YP_004098111.1 COGs: COG2057 acyl CoA:acetate/3-ketoacid CoA transferase subunit beta; InterPro IPR004165: IPR012791; KEGG: scb:SCAB_6611 3-oxoadipate CoA-transferase subunit; PFAM: coenzyme A transferase; PRIAM: 3-oxoadipate CoA-transferase; SPTR: Butyryl-CoA:acetate CoA transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit YP_004098112.1 COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: kse:Ksed_01340 toxin-antitoxin system, toxin component, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; SPTR: Toxin-antitoxin system, toxin component, Txe/YoeB family; TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family YP_004098113.1 InterPro IPR006442; KEGG: kse:Ksed_01350 prevent-host-death family protein; SPTR: uncharacterized protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004098114.1 KEGG: cci:CC1G_06373 AGC/YANK protein kinase; SPTR: Lct17 YP_004098115.1 COGs: COG0580 glycerol uptake facilitator and related permease (Major Intrinsic protein Family); InterPro IPR000425: IPR012269; KEGG: fpl:Ferp_1369 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel protein; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_004098116.1 COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR014184: IPR002328; KEGG: gob:Gobs_4986 formaldehyde dehydrogenase, glutathione-independent; PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; SPTR: Formaldehyde dehydrogenase, glutathione-independent; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent YP_004098117.1 COGs: COG4584 transposase and inactivated derivatives; InterPro IPR001584; KEGG: dap:Dacet_2820 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: transposase; PFAM: Integrase core domain YP_004098118.1 COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: rha:RHA1_ro06914 insertion sequence ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: ATPase AAA; SPTR: Probable insertion sequence ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004098119.1 InterPro IPR002934; KEGG: kfl:Kfla_0120 hypothetical protein; PFAM: DNA polymerase beta domain protein region; SPTR: uncharacterized protein; PFAM: nucleotidyltransferase domain YP_004098120.1 KEGG: xce:Xcel_2885 hypothetical protein; SPTR: uncharacterized protein YP_004098121.1 InterPro IPR001647; KEGG: scb:SCAB_42741 TetR family regulator; PFAM: regulatory protein TetR; SPTR: Probable transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004098122.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149; KEGG: scb:SCAB_77001 zinc-binding dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: Zinc-binding oxidoreductase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004098123.1 KEGG: art:Arth_0670 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004098124.1 KEGG: mbt:JTY_2670 hypothetical protein; SPTR: uncharacterized protein Mb2682 YP_004098125.1 KEGG: mbt:JTY_2669 hypothetical protein; SPTR: uncharacterized protein Mb2681; PFAM: protein of unknown function (DUF497) YP_004098126.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR002410: IPR000073: IPR005944; KEGG: kse:Ksed_01230 proline iminopeptidase; PFAM: alpha/beta hydrolase fold; PRIAM: prolyl aminopeptidase; SPTR: Proline iminopeptidase; TIGRFAM: proline iminopeptidase; manually curated; PFAM: alpha/beta hydrolase fold; TIGRFAM: proline iminopeptidase, Neisseria-type subfamily YP_004098127.1 KEGG: cai:Caci_8101 hypothetical protein; SPTR: uncharacterized protein YP_004098128.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: nca:Noca_0600 phage integrase; PFAM: integrase; integrase; SPTR: Phage integrase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family YP_004098129.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nca:Noca_0601 phage integrase; PFAM: integrase; SPTR: Phage integrase; PFAM: Phage integrase family YP_004098130.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nca:Noca_0602 phage integrase; PFAM: integrase; SPTR: Phage integrase; PFAM: Phage integrase family YP_004098131.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: mlu:Mlut_14300 transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: transposase; PFAM: transposase YP_004098132.1 COGs: COG3344 Retron-type reverse transcriptase; InterPro IPR000477: IPR013597; KEGG: rha:RHA1_ro10191 RNA-directed DNA polymerase; PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; PRIAM: RNA-directed DNA polymerase; SPTR: RNA-directed DNA polymerase; PFAM: Reverse transcriptase (RNA-dependent DNA polymerase); Group II intron, maturase-specific domain YP_004098133.1 COGs: COG1819 glycosyl transferase related to UDP-glucuronosyltransferase; InterPro IPR002213; KEGG: nml:Namu_2594 UDP-glucuronosyl/UDP-glucosyltransferase; PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; SPTR: UDP-glucuronosyl/UDP-glucosyltransferase; PFAM: UDP-glucoronosyl and UDP-glucosyl transferase; TIGRFAM: glycosyltransferase, MGT family YP_004098134.1 InterPro IPR001647; KEGG: aau:AAur_pTC20015 transcription regulator, TetR family; PFAM: regulatory protein TetR; SPTR: transcription regulator, TetR Family; PFAM: Bacterial regulatory proteins, tetR family YP_004098135.1 InterPro IPR000834; KEGG: stp:Strop_1703 peptidase M14, carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; SPTR: peptidase M14, carboxypeptidase A; PFAM: Zinc carboxypeptidase; Immune inhibitor A peptidase M6 YP_004098136.1 COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; KEGG: bcv:Bcav_0899 DNA helicase; SPTR: uncharacterized protein YP_004098137.1 KEGG: sna:Snas_3081 hypothetical protein; SPTR: uncharacterized protein YP_004098138.1 COGs: COG1970 Large-conductance mechanosensitive channel; InterPro IPR001185: IPR019823; KEGG: pfr:PFREUD_18050 large conductance mechanosensitive channel; PFAM: large-conductance mechanosensitive channel; SPTR: Large conductance mechanosensitive channel; TIGRFAM: large conductance mechanosensitive channel protein; PFAM: Large-conductance mechanosensitive channel, MscL; TIGRFAM: large conductance mechanosensitive channel protein YP_004098139.1 InterPro IPR013974; KEGG: kra:Krad_3695 SAF domain protein; PFAM: SAF domain protein; SPTR: SAF domain protein; PFAM: SAF domain YP_004098140.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845: IPR010044; KEGG: scb:SCAB_53071 methylthioadenosine phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: methylthioadenosine phosphorylase; TIGRFAM: methylthioadenosine phosphorylase; PFAM: phosphorylase superfamily; TIGRFAM: 5'-deoxy-5'-methylthioadenosine phosphorylase YP_004098141.1 COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: ske:Sked_30590 regulatory protein, FmdB family; PFAM: regulatory protein FmdB; SPTR: regulatory protein, FmdB family; TIGRFAM: regulatory protein, FmdB family; manually curated; PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family YP_004098142.1 COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006037: IPR006153; KEGG: kra:Krad_3692 potassium/proton antiporter; PFAM: sodium/hydrogen exchanger; TrkA-C domain protein; SPTR: cell volume regulation protein CvrA; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family; TC 2.A.36 YP_004098143.1 COGs: COG2366 protein related to penicillin acylase; InterPro IPR002692: IPR014395: IPR002034; KEGG: cfl:Cfla_0835 peptidase S45 penicillin amidase; PFAM: peptidase S45 penicillin amidase; SPTR: Penicillin amidase; PFAM: Penicillin amidase YP_004098144.1 COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: kse:Ksed_23890 5,10-methenyltetrahydrofolate synthetase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5,10-methenyltetrahydrofolate synthetase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_004098145.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterProIPR002618: IPR005110: IPR001453: IPR005111: IPR 020817; KEGG: kfl:Kfla_5768 UTP--glucose-1-phosphate uridylyltransferase; PFAM: UTP--glucose-1-phosphate uridylyltransferase; MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); UTP--glucose-1-phosphate uridylyltransferase; MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain YP_004098146.1 COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: gob:Gobs_4471 molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis protein MoaC; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC YP_004098147.1 COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR020817: IPR008284; KEGG: kfl:Kfla_5764 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: molybdopterin biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain YP_004098148.1 COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: sgr:SGR_4300 ribosomal-protein-alanine N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: ribosomal-protein-alanine N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004098149.1 KEGG: kse:Ksed_23860 hypothetical protein; SPTR: uncharacterized protein YP_004098150.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: kfl:Kfla_5640 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: integral membrane protein; PFAM: Domain of unknown function DUF20 YP_004098151.1 COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: rha:RHA1_ro02437 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF72 YP_004098152.1 KEGG: nca:Noca_2699 hypothetical protein; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004098153.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: mjl:Mjls_1690 alcohol dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: alcohol dehydrogenase, zinc-binding domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004098154.1 KEGG: tbi:Tbis_0638 hypothetical protein YP_004098155.1 InterPro IPR002781; KEGG: mpt:Mpe_A0917 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004098156.1 COGs: COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase; InterPro IPR003342; KEGG: kra:Krad_3667 glycosyl transferase family 39; PFAM: glycosyl transferase family 39; SPTR: integral membrane protein; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase YP_004098157.1 InterPro IPR003675; KEGG: pac:PPA0317 protease; PFAM: hypothetical protein; SPTR: Conserved protein, protease; PFAM: CAAX amino terminal protease family YP_004098158.1 KEGG: nca:Noca_2785 hypothetical protein; SPTR: uncharacterized protein; PFAM: Dienelactone hydrolase family YP_004098159.1 COGs: COG0313 methyltransferase; InterPro IPR000878: IPR008189; KEGG: sco:SCO3153 hypothetical protein; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: tetrapyrrole methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family YP_004098160.1 COGs: COG1764 redox protein regulator of disulfide bond formation; InterPro IPR003718: IPR019904; KEGG: nca:Noca_1377 OsmC family protein; PFAM: OsmC family protein; SPTR: ATP/GTP-binding protein; TIGRFAM: peroxiredoxin, OsmC subfamily; PFAM: OsmC-like protein; TIGRFAM: peroxiredoxin, OsmC subfamily YP_004098161.1 COGs: COG0143 Methionyl-tRNA synthetase; InterPro IPR014758: IPR015413: IPR002304; KEGG: nca:Noca_1386 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); SPTR: Methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; PFAM: tRNA synthetases class I (M); TIGRFAM: methionyl-tRNA synthetase YP_004098162.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130: IPR012278: IPR015991; KEGG: kse:Ksed_03330 hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; SPTR: uncharacterized protein; TIGRFAM: hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_004098163.1 COGs: COG3583 conserved hypothetical protein; InterPro IPR011098: IPR007137: IPR010618; KEGG: kfl:Kfla_5728 transglycosylase domain protein; PFAM: transglycosylase; G5 domain protein; protein of unknown function DUF348; SPTR: uncharacterized protein; PFAM: transglycosylase-like domain; Domain of unknown function (DUF348); G5 domain YP_004098164.1 COGs: COG0030 dimethyladenosine transferase (rRNA methylation); InterPro IPR020598: IPR011530: IPR001737: IPR020596; KEGG: kse:Ksed_03390 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: ribosomal RNA adenine methylase transferase-like; SPTR: ribosomal RNA small subunit methyltransferase A; TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_004098165.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; InterPro IPR004424: IPR006204: IPR013750; KEGG: mjl:Mjls_4641 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004098166.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439: IPR017871; KEGG: kse:Ksed_03410 ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding subunit; PFAM: ABC transporter YP_004098167.1 COGs: COG2132 multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR006311; KEGG: tbd:Tbd_1072 hypothetical protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; SPTR: uncharacterized protein; PFAM: Multicopper oxidase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004098168.1 InterPro IPR000421: IPR001842; KEGG: rxy:Rxyl_2538 coagulation factor 5/8 type-like protein; PFAM: peptidase M36 fungalysin; coagulation factor 5/8 type domain protein; SPTR: Coagulation factor 5/8 type-like protein; PFAM: F5/8 type C domain; Fungalysin/Thermolysin propeptide Motif; Fungalysin metallopeptidase (M36) YP_004098169.1 COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: scb:SCAB_54041 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR-family regulator; PFAM: MarR family YP_004098170.1 COGs: COG4106 trans-aconitate methyltransferase; InterPro IPR013216; KEGG: aau:AAur_2078 trans-aconitate 2-methyltransferase; PFAM: methyltransferase type 11; PRIAM: trans-aconitate 2-methyltransferase; SPTR: trans-aconitate methyltransferase; PFAM: methyltransferase domain YP_004098171.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: cai:Caci_6132 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004098172.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: kfl:Kfla_5712 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: TetR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004098173.1 InterPro IPR018114; KEGG: sro:Sros_2627 hypothetical protein; SPTR: uncharacterized protein YP_004098174.1 COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR005882: IPR001228: IPR001451; KEGG: kfl:Kfla_5708 UDP-N-acetylglucosamine pyrophosphorylase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; transferase hexapeptide repeat containing protein; SPTR: Bifunctional protein glmU; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_004098175.1 COGs: COG0462 phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946: IPR000842: IPR019793; KEGG: kfl:Kfla_5707 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: ribose-phosphate diphosphokinase; SPTR: ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004098176.1 InterPro IPR010852; KEGG: nml:Namu_5293 protein of unknown function DUF1470; PFAM: protein of unknown function DUF1470; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1470); CGNR zinc finger YP_004098177.1 InterPro IPR000620; KEGG: nml:Namu_5292 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004098178.1 COGs: COG1825 ribosomal protein L25 (general stress protein Ctc); InterPro IPR020055: IPR001021; KEGG: kfl:Kfla_5703 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: ribosomal protein L25-like; SPTR: 50S ribosomal protein L25; TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form YP_004098179.1 COGs: COG0193 peptidyl-tRNA hydrolase; InterPro IPR001328: IPR018171; KEGG: ach:Achl_1290 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_004098180.1 COGs: COG1197 transcription-repair coupling factor (superfamily II helicase); InterProIPR014001: IPR001650: IPR014021: IPR003711: IPR 011545: IPR005118: IPR004576; KEGG: kse:Ksed_07020 transcription-repair coupling factor Mfd; PFAM: transcription factor CarD; DEAD/DEAH box helicase domain protein; helicase; TRCF domain protein; SMART: DEAD-like helicase; helicase; SPTR: transcriptional-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd) YP_004098181.1 KEGG: bcv:Bcav_1015 hypothetical protein; SPTR: uncharacterized protein YP_004098182.1 COGs: COG3956 protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518: IPR011551; KEGG: kfl:Kfla_5699 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: uncharacterized protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_004098183.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362: IPR017475: IPR017871; KEGG: bfa:Bfae_02670 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; PRIAM: undecaprenyl-phosphate galactose phosphotransferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: undecaprenyl-phosphate galactose phosphotransferase, WbaP; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_004098184.1 COGs: COG0148 Enolase; InterPro IPR000941: IPR020811: IPR020810: IPR020809; KEGG: kse:Ksed_07040 enolase; PFAM: Enolase-like; PRIAM: phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: enolase; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004098185.1 InterPro IPR007060; KEGG: kra:Krad_1074 septum formation initiator; PFAM: septum formation initiator; SPTR: septum formation initiator; PFAM: septum formation initiator YP_004098186.1 COGs: COG1507 conserved hypothetical protein; InterPro IPR007511; KEGG: kse:Ksed_07060 hypothetical protein; PFAM: protein of unknown function DUF501; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF501) YP_004098187.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: ske:Sked_07880 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: exopolyphosphatase; PFAM: Ppx/GppA phosphatase family YP_004098188.1 COGs: COG4760 membrane protein; InterPro IPR019825; KEGG: kse:Ksed_07090 predicted membrane protein; SPTR: integral membrane protein YP_004098189.1 KEGG: stp:Strop_0907 hypothetical protein; SPTR: uncharacterized protein YP_004098190.1 COGs: COG0183 acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR020613: IPR002155; KEGG: kse:Ksed_07120 acetyl-CoA acetyltransferase; PFAM: thiolase-like; PRIAM: acetyl-CoA C-acyltransferase; SPTR: acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase, C-terminal domain; thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_004098191.1 KEGG: cwo:Cwoe_3353 hypothetical protein; SPTR: uncharacterized protein YP_004098192.1 InterPro IPR001087; KEGG: nca:Noca_0938 GDSL family lipase; PFAM: lipolytic protein G-D-S-L family; SPTR: secreted protein; PFAM: GDSL-like Lipase/acylhydrolase YP_004098193.1 COGs: COG0031 Cysteine synthase; InterProIPR001926: IPR000644: IPR005829: IPR001216: IPR 005857; KEGG: rha:RHA1_ro05843 cystathionine beta-synthase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: cystathionine beta-synthase; TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain; pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase YP_004098194.1 InterPro IPR000792; KEGG: kfl:Kfla_5405 transcriptional regulator, TrmB; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: transcriptional regulator, TrmB; PFAM: Sugar-specific transcriptional regulator TrmB; Bacterial regulatory proteins, luxR family YP_004098195.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR010259: IPR000209: IPR017909; KEGG: dge:Dgeo_0978 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; SPTR: Thermophilic protease; PFAM: peptidase inhibitor I9; Subtilase family YP_004098196.1 COGs: COG0449 glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: kra:Krad_0771 glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); PRIAM: glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: glutamine--fructose-6-phosphate transaminase (Isomerizing); PFAM: SIS domain YP_004098197.1 COGs: COG2186 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sro:Sros_2470 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: Regulatory protein GntR HTH; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004098198.1 COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR019546: IPR000914: IPR017909: IPR006311; KEGG: sgr:SGR_6426 ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 5; Twin-arginine translocation pathway, signal sequence, subgroup; SPTR: extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004098199.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: rer:RER_09420 ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004098200.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR000515: IPR003439: IPR013563: IPR017871: IPR 010066: IPR003593; KEGG: sma:SAV_5609 ABC transporter permease protein; PFAM: ABC transporter; binding-protein-dependent transporters inner membrane component; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; Binding-protein-dependent transporter inner membrane component; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004098201.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR003439: IPR013563: IPR017871: IPR010066: IPR 003593; KEGG: sma:SAV_5608 ABC transporter ATP-binding protein; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004098202.1 COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR020625; KEGG: sro:Sros_2475 dihydropicolinate synthase family protein; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase family YP_004098203.1 COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600: IPR002328; KEGG: bcv:Bcav_3770 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family YP_004098204.1 COGs: COG3010 N-acetylmannosamine-6-phosphate epimerase; InterPro IPR007260; KEGG: sro:Sros_2477 N-acylglucosamine-6-phosphate 2-epimerase; PFAM: N-acetylmannosamine-6-phosphate epimerase; PRIAM: N-acylglucosamine-6-phosphate 2-epimerase; SPTR: N-acetylmannosamine-6-phosphate 2-epimerase; PFAM: N-acetylmannosamine-6-phosphate epimerase YP_004098205.1 COGs: COG0657 esterase/lipase; InterPro IPR002168; KEGG: mkm:Mkms_0324 alpha/beta hydrolase; SPTR: alpha/beta hydrolase fold-3; PFAM: alpha/beta hydrolase fold YP_004098206.1 InterPro IPR003265: IPR017658; KEGG: sgr:SGR_3531 hypothetical protein; PFAM: HhH-GPD family protein; SPTR: HhH-GPD family protein; TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: uncharacterized HhH-GPD family protein YP_004098207.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR001498: IPR015269: IPR020569; KEGG: nca:Noca_0960 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; Uncharacterised protein family UPF0029, Impact, C-terminal; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family YP_004098208.1 COGs: COG0239 integral membrane protein possibly involved in chromosome condensation; InterPro IPR003691; KEGG: nfa:nfa44550 camphor resistance protein CrcB; PFAM: Camphor resistance CrcB protein; SPTR: Camphor resistance protein; TIGRFAM: CrcB protein; PFAM: CrcB-like protein; TIGRFAM: crcB protein YP_004098209.1 COGs: COG0239 integral membrane protein possibly involved in chromosome condensation; InterPro IPR003691; KEGG: fre:Franean1_1439 CrcB protein; PFAM: Camphor resistance CrcB protein; SPTR: CrcB-like protein; TIGRFAM: CrcB protein; PFAM: CrcB-like protein; TIGRFAM: crcB protein YP_004098210.1 COGs: COG2138 conserved hypothetical protein; InterPro IPR002762; KEGG: ske:Sked_00880 hypothetical protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; SPTR: Uncharacterized conserved protein; PFAM: CbiX YP_004098211.1 InterPro IPR019965; KEGG: rop:ROP_15660 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: F420-dependent enzyme; TIGRFAM: PPOX class probable F420-dependent enzyme, Rv2061 family YP_004098212.1 COGs: COG2114 adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000073: IPR001054; KEGG: mav:MAV_5228 hydrolase, alpha/beta hydrolase fold family protein; PFAM: alpha/beta hydrolase fold; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Hydrolase, alpha/beta hydrolase fold family protein; PFAM: adenylate and Guanylate cyclase catalytic domain; alpha/beta hydrolase fold YP_004098213.1 InterPro IPR012312; KEGG: ace:Acel_0494 hemerythrin HHE cation binding domain-containing protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin HHE cation binding domain protein; PFAM: hemerythrin HHE cation binding domain YP_004098214.1 InterPro IPR012544; KEGG: gob:Gobs_1634 protein of unknown function DUF1696; PFAM: protein of unknown function DUF1696; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1696) YP_004098215.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: kra:Krad_4263 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004098216.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712: IPR003594; KEGG: pak:HMPREF0675_3336 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: two-component sensor kinase; PFAM: histidine kinase YP_004098217.1 KEGG: ske:Sked_25600 hypothetical protein; SPTR: uncharacterized protein; PFAM: Telomeric repeat-binding factor 2 YP_004098218.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR005580: IPR000629: IPR 014021: IPR014014: IPR014001; KEGG: nca:Noca_4601 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase; helicase; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase; SPTR: DEAD/DEAH box helicase; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase YP_004098219.1 KEGG: saq:Sare_1132 hypothetical protein; SPTR: uncharacterized protein YP_004098220.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048: IPR019921; KEGG: tcu:Tcur_2334 luciferase-like monooxygenase; PFAM: Luciferase-like, subgroup; SPTR: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable F420-dependent oxidoreductase, Rv2161c family YP_004098221.1 COGs: COG1621 beta-fructosidase (levanase/invertase); InterPro IPR013148; KEGG: fre:Franean1_7054 glycosyl hydrolase family 32 protein; PFAM: glycosyl hydrolase family 32 domain protein; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 32 N-terminal domain YP_004098222.1 COGs: COG0702 nucleoside-diphosphate-sugar epimerase; KEGG: xcv:XCV0349 hypothetical protein; SPTR: uncharacterized protein; PFAM: NmrA-like family YP_004098223.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: nca:Noca_1790 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: esterase/lipase YbfF; PFAM: alpha/beta hydrolase fold YP_004098224.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: bcv:Bcav_3033 two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; SPTR: two-component system DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004098225.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR007168: IPR003594; KEGG: art:Arth_2999 signal transduction histidine kinase; PFAM: PspC domain protein; ATP-binding region ATPase domain protein; SPTR: signal transduction histidine kinase; PFAM: PspC domain YP_004098226.1 InterPro IPR007168; KEGG: art:Arth_3000 phage shock protein C, PspC; PFAM: PspC domain protein; SPTR: uncharacterized protein; PFAM: PspC domain YP_004098227.1 KEGG: ske:Sked_28350 hypothetical protein; SPTR: uncharacterized protein YP_004098228.1 COGs: COG3590 metalloendopeptidase; InterPro IPR008753: IPR018497; KEGG: cfl:Cfla_1374 neprilysin; PFAM: peptidase M13; peptidase M13, neprilysin-like; PRIAM: endothelin-converting enzyme 1; SPTR: peptidase; PFAM: peptidase family M13 YP_004098229.1 InterPro IPR000182; KEGG: sco:SCO3913 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004098230.1 InterPro IPR019587; KEGG: kse:Ksed_03110 polyketide cyclase / dehydrase and lipid transport; PFAM: polyketide cyclase/dehydrase; SPTR: polyketide cyclase / dehydrase and lipid transport; PFAM: polyketide cyclase / dehydrase and lipid transport YP_004098231.1 InterPro IPR001343: IPR018511: IPR003995; KEGG: kfl:Kfla_0735 RTX toxins and related Ca2+-binding protein-like protein; SPTR: RTX toxins and related Ca2+-binding protein-like protein YP_004098232.1 KEGG: scb:SCAB_82841 integral membrane transport protein; SPTR: uncharacterized protein YP_004098233.1 COGs: COG3899 ATPase; InterPro IPR000792; KEGG: tcu:Tcur_0848 LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family YP_004098234.1 COGs: COG0578 glycerol-3-phosphate dehydrogenase; InterPro IPR006076: IPR000447; KEGG: tpr:Tpau_1956 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; PRIAM: glycerol-3-phosphate dehydrogenase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase YP_004098235.1 KEGG: fal:FRAAL1574 TetR family transcriptional regulator; SPTR: TetR-family transcriptional regulator YP_004098236.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: cwo:Cwoe_5413 alkylglycerone-phosphate synthase; PFAM: FAD linked oxidase; PRIAM: Alkylglycerone-phosphate synthase; SPTR: Alkylglycerone-phosphate synthase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain YP_004098237.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206: IPR005218; KEGG: fra:Francci3_3822 hypothetical protein; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase; SPTR: uncharacterized protein; PFAM: diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family YP_004098238.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: gbr:Gbro_4403 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR-family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_004098239.1 KEGG: cak:Caul_4789 protein of unknown function DUF853 NPT hydrolase SPTR: Predicted ATPase YP_004098240.1 COGs: COG0225 peptide methionine sulfoxide reductase; InterPro IPR002569; KEGG: kra:Krad_1091 peptide methionine sulfoxide reductase; PFAM: methionine sulfoxide reductase A; PRIAM: peptide-methionine (S)-S-oxide reductase; SPTR: methionine sulfoxide reductase A; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase YP_004098241.1 COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_0976 cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004098242.1 InterPro IPR000560: IPR006230; KEGG: stp:Strop_2268 hypothetical protein; SPTR: glutamate mutase, mutL; TIGRFAM: conserved hypothetical protein YP_004098243.1 COGs: COG0782 transcription elongation factor; InterPro IPR001437: IPR018151: IPR006359; KEGG: kse:Ksed_07260 transcription elongation factor; PFAM: transcription elongation factor GreA/GreB domain-containing protein; SPTR: transcription elongation factor; TIGRFAM: transcription elongation factor GreA; PFAM: domain; transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA YP_004098244.1 KEGG: kse:Ksed_07270 hypothetical protein; SPTR: uncharacterized protein YP_004098245.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737: IPR017811; KEGG: kse:Ksed_07280 mycothiol conjugate amidase Mca; PFAM: LmbE family protein; SPTR: uncharacterized protein; TIGRFAM: mycothiol conjugate amidase Mca; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: mycothiol conjugate amidase Mca YP_004098246.1 KEGG: kse:Ksed_07290 hypothetical protein; SPTR: uncharacterized protein YP_004098247.1 COGs: COG1272 membrane protein hemolysin III homolog; InterPro IPR004254; KEGG: kra:Krad_1104 Hly-III family protein; PFAM: Hly-III family protein; SPTR: integral membrane protein; PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family YP_004098248.1 COGs: COG0020 undecaprenyl pyrophosphate synthase; InterPro IPR001441; KEGG: nca:Noca_1056 undecaprenyl pyrophosphate synthetase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Di-trans-poly-cis-decaprenylcistransferase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_004098249.1 COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR003714: IPR006596; KEGG: nca:Noca_1057 PhoH family protein; PFAM: PhoH family protein; SMART: nucleotide binding protein PINc; SPTR: ATP-binding protein; PFAM: PhoH-like protein YP_004098250.1 KEGG: kra:Krad_1108 secreted protein; SPTR: Secreted protein YP_004098251.1 COGs: COG1072 Panthothenate kinase; InterPro IPR004566; KEGG: kra:Krad_0723 pantothenate kinase; SPTR: Pantothenate kinase; TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase / Uridine kinase family; TIGRFAM: pantothenate kinase, bacterial type YP_004098252.1 COGs: COG0449 glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR000583: IPR001347: IPR005855: IPR017932; KEGG: kse:Ksed_07350 glucosamine--fructose-6-phosphate aminotransferase; PFAM: sugar isomerase (SIS); glutamine amidotransferase class-II; SPTR: D-fructose-6-phosphate amidotransferase; TIGRFAM: glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: SIS domain; glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing) YP_004098253.1 COGs: COG0736 phosphopantetheinyl transferase (holo-ACP synthase); InterPro IPR008278: IPR004568: IPR002582; KEGG: nca:Noca_0897 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: 4'-phosphopantetheinyl transferase; TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase YP_004098254.1 COGs: COG0063 sugar kinase; InterPro IPR004443: IPR000631: IPR017953; KEGG: cfl:Cfla_2602 carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain-containing protein; protein of unknown function UPF0031; SPTR: uncharacterized protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related YP_004098255.1 COGs: COG0787 alanine racemase; InterPro IPR001608: IPR011079: IPR020622: IPR000821; KEGG: fre:Franean1_6011 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: alanine racemase; SPTR: alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase, C-terminal domain; alanine racemase, N-terminal domain; TIGRFAM: alanine racemase YP_004098256.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073: IPR000639; KEGG: sma:SAV_4968 hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: hydrolase; PFAM: alpha/beta hydrolase fold YP_004098257.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: kra:Krad_0729 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family YP_004098258.1 KEGG: art:Arth_1264 hypothetical protein; SPTR: uncharacterized protein YP_004098259.1 COGs: COG1214 Inactive homolog of metal-dependent protease molecular chaperone; InterPro IPR000905; KEGG: sgr:SGR_2781 hypothetical protein; PFAM: peptidase M22 glycoprotease; SPTR: uncharacterized protein; PFAM: glycoprotease family; TIGRFAM: universal bacterial protein YeaZ YP_004098260.1 COGs: COG0456 acetyltransferase; InterPro IPR000182: IPR006464; KEGG: kse:Ksed_07490 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase YP_004098261.1 COGs: COG0533 metal-dependent protease with chaperone activity; InterPro IPR000905: IPR017860: IPR017861; KEGG: kse:Ksed_07500 DNA-binding/iron metalloprotein/AP endonuclease; PFAM: peptidase M22 glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: O-sialoglycoprotein endopeptidase; TIGRFAM: metalloendopeptidase, glycoprotease family; PFAM: glycoprotease family; TIGRFAM: glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family YP_004098262.1 COGs: COG1472 beta-glucosidase-related glycosidase; InterPro IPR001764: IPR019800; KEGG: kfl:Kfla_0946 glycoside hydrolase family 3 domain protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: beta-N-acetylhexosaminidase; PFAM: glycosyl hydrolase family 3 N terminal domain YP_004098263.1 COGs: COG1957 inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910: IPR022272; KEGG: kfl:Kfla_4700 inosine/uridine-preferring nucleoside hydrolase; PFAM: inosine/uridine-preferring nucleoside hydrolase; SPTR: inosine/uridine-preferring nucleoside hydrolase; PFAM: inosine-uridine preferring nucleoside hydrolase YP_004098264.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173: IPR002139; KEGG: cmi:CMM_0942 hypothetical protein; PFAM: PfkB domain protein; SPTR: ribokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase YP_004098265.1 KEGG: krh:KRH_06700 hypothetical protein; SPTR: uncharacterized protein YP_004098266.1 COGs: COG0234 Co-chaperonin GroES (HSP10); InterPro IPR020818: IPR018369: IPR001476; KEGG: sro:Sros_1154 co-chaperonin GroES; PFAM: chaperonin Cpn10; SPTR: 10 kDa chaperonin; PFAM: chaperonin 10 Kd subunit YP_004098267.1 COGs: COG0459 chaperonin GroEL (HSP60 family); InterPro IPR002423: IPR018370: IPR001844; KEGG: kra:Krad_0736 chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: chaperonin GroEL; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004098268.1 InterPro IPR003482; KEGG: kra:Krad_0737 transcription factor WhiB; PFAM: transcription factor WhiB; SPTR: transcription factor WhiB; PFAM: transcription factor WhiB YP_004098269.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004098270.1 KEGG: fre:Franean1_2214 hypothetical protein; SPTR: uncharacterized protein YP_004098271.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR001093: IPR000644: IPR015875: IPR005990: IPR 018529; KEGG: nca:Noca_3645 inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_004098272.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093: IPR005992; KEGG: kra:Krad_0743 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; SPTR: IMP dehydrogenase family protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein YP_004098273.1 COGs: COG2303 Choline dehydrogenase and related flavoprotein; InterPro IPR013027; KEGG: rer:RER_19350 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: cholesterol oxidase; PFAM: GMC oxidoreductase YP_004098274.1 KEGG: amd:AMED_2730 hypothetical protein; SPTR: uncharacterized protein YP_004098275.1 KEGG: nml:Namu_0314 CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase YP_004098276.1 InterPro IPR000462; KEGG: saq:Sare_2752 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_004098277.1 COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR006076; KEGG: nca:Noca_1679 dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: dehydrogenase; PFAM: FAD dependent oxidoreductase YP_004098278.1 COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; KEGG: tcu:Tcur_2746 hypothetical protein; SPTR: uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase YP_004098279.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: saq:Sare_2749 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004098280.1 KEGG: saq:Sare_2748 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104) YP_004098281.1 COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR002734; KEGG: nca:Noca_1683 deaminase-reductase domain-containing protein; PFAM: bifunctional deaminase-reductase domain protein; SPTR: Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain YP_004098282.1 COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: saq:Sare_2747 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II YP_004098283.1 COGs: COG3346 conserved hypothetical protein; InterPro IPR002994; KEGG: kse:Ksed_07660 hypothetical protein; SPTR: uncharacterized protein; PFAM: SURF1 family YP_004098284.1 KEGG: rop:ROP_11390 hypothetical membrane protein; SPTR: Hypothetical membrane protein YP_004098285.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR000991: IPR001674: IPR017926: IPR004739: IPR 011702: IPR006220: IPR001317; KEGG: kse:Ksed_07680 GMP synthase (glutamine-hydrolyzing); PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: Bifunctional GMP synthase/glutamine amidotransferase protein; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: glutamine amidotransferase class-I; GMP synthase C terminal domain; Asparagine synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or subunit alpha YP_004098286.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterProIPR000583: IPR001962: IPR002847: IPR017932: IPR 006426; KEGG: rsa:RSal33209_2004 asparagine synthetase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; protein of unknown function DUF129; SPTR: Asparagine synthetase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: F420-0:gamma-glutamyl ligase; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_004098287.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: cmi:CMM_1418 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme YP_004098288.1 COGs: COG0392 integral membrane protein; KEGG: nml:Namu_1430 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein YP_004098289.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: nml:Namu_1432 LmbE family protein; PFAM: LmbE family protein; SPTR: uncharacterized protein; PFAM: GlcNAc-PI de-N-acetylase YP_004098291.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR003593; KEGG: tws:TW106 ABC transport ATP-binding subunit; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transport ATP-binding subunit; PFAM: ABC transporter YP_004098293.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: msm:MSMEG_5398 ISMsm4, transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: ISMsm4, transposase; PFAM: transposase YP_004098294.1 InterPro IPR003004; KEGG: pak:HMPREF0675_4973 hypothetical protein; SPTR: uncharacterized protein YP_004098295.1 KEGG: pak:HMPREF0675_4975 hypothetical protein; SPTR: Hypothetical membrane protein YP_004098296.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: cfl:Cfla_2548 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004098297.1 InterPro IPR000086: IPR020084: IPR020476; KEGG: pak:HMPREF0675_3603 hydrolase, NUDIX family; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004098298.1 KEGG: rha:RHA1_ro05895 hypothetical protein; SPTR: uncharacterized protein YP_004098299.1 KEGG: aca:ACP_2010 hypothetical protein; SPTR: uncharacterized protein YP_004098300.1 COGs: COG2128 conserved hypothetical protein; InterPro IPR003779: IPR004675; KEGG: nca:Noca_0825 alkylhydroperoxidase; PFAM: carboxymuconolactone decarboxylase; SPTR: Alkylhydroperoxidase like protein, AhpD family; TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain YP_004098301.1 KEGG: nca:Noca_4159 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF559) YP_004098302.1 COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: sro:Sros_4594 secreted protein; PFAM: amidohydrolase; SPTR: secreted protein; PFAM: Amidohydrolase family YP_004098303.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149; KEGG: sen:SACE_2164 quinone oxidoreductase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: Quinone oxidoreductase, ; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004098304.1 InterPro IPR000182; KEGG: tfu:Tfu_0561 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004098305.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212: IPR014016: IPR014017: IPR005751; KEGG: kse:Ksed_07720 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase II; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA YP_004098306.1 COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sco:SCO4108 peptidase; PFAM: peptidase M23; SPTR: peptidase; PFAM: peptidase family M23 YP_004098307.1 COGs: COG1075 acetyltransferase and hydrolase with the alpha/beta hydrolase fold; InterPro IPR000073; KEGG: kfl:Kfla_1265 lipase class 2; PFAM: alpha/beta hydrolase fold; SPTR: secreted lipase; PFAM: serine esterase (DUF676) YP_004098308.1 COGs: COG2185 methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006158: IPR006159; KEGG: saq:Sare_4204 cobalamin B12-binding domain-containing protein; PFAM: cobalamin B12-binding domain protein; SPTR: Cobalamin B12-binding domain protein; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain YP_004098309.1 COGs: COG0785 cytochrome C biogenesis protein; InterPro IPR003834; KEGG: sco:SCO5994 integral membrane cytochrome biogenesis protein; PFAM: cytochrome C biogenesis protein transmembrane region; SPTR: integral membrane cytochrome biogenesis protein; PFAM: cytochrome C biogenesis protein transmembrane region YP_004098310.1 COGs: COG1651 protein-disulfide isomerase; InterPro IPR001853: IPR017936; KEGG: sen:SACE_0617 DsbA-like thioredoxin domain-containing protein; PFAM: DSBA oxidoreductase; SPTR: DSBA oxidoreductase; PFAM: DSBA-like thioredoxin domain YP_004098311.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001845: IPR001763: IPR001307; KEGG: sen:SACE_4409 ArsR family transcriptional regulator; PFAM: Rhodanese domain protein; regulatory protein ArsR; SMART: rhodanese; regulatory protein ArsR; SPTR: Possible transcriptional regulatory protein (Possibly ArsR-family); PFAM: Bacterial regulatory protein, arsR family; Rhodanese-like domain YP_004098312.1 COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650: IPR005811: IPR005809: IPR011761; KEGG: cfl:Cfla_2537 succinyl-CoA synthetase subunit beta; PFAM: ATP-grasp domain protein; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: succinate--CoA ligase (ADP-forming); SPTR: Succinyl-CoA ligase [ADP-forming] subunit beta; TIGRFAM: succinyl-CoA synthetase subunit beta; PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase subunit beta YP_004098313.1 COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR003781: IPR005811: IPR017440: IPR005810; KEGG: kse:Ksed_07740 succinyl-CoA synthetase subunit alpha; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; SPTR: Succinyl-CoA ligase [ADP-forming] subunit alpha; TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA binding domain; CoA-ligase; TIGRFAM: succinyl-CoA synthetase, subunit alpha YP_004098314.1 KEGG: bcv:Bcav_3015 hypothetical protein; SPTR: uncharacterized protein YP_004098315.1 KEGG: kse:Ksed_07770 hypothetical protein; SPTR: uncharacterized protein YP_004098316.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR002376: IPR004607; KEGG: ami:Amir_6504 phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; SPTR: phosphoribosylglycinamide formyltransferase; TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_004098317.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607: IPR013982: IPR002695; KEGG: cfl:Cfla_2532 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_004098318.1 InterPro IPR014086; KEGG: nca:Noca_1505 barbiturase; PFAM: Amidohydrolase ring-opening AtzD/TrzD; PRIAM: Barbiturase; SPTR: Cyanuric acid amidohydrolase; TIGRFAM: ring-opening amidohydrolase; PFAM: Amidohydrolase ring-opening protein (Amido_AtzD_TrzD); TIGRFAM: ring-opening amidohydrolases YP_004098319.1 COGs: COG0549 carbamate kinase; InterPro IPR001048: IPR003964; KEGG: cai:Caci_1878 carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: carbamate kinase; SPTR: carbamate kinase; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase YP_004098320.1 KEGG: ach:Achl_1570 cell division protein FtsW; SPTR: Amino acid permease-associated region YP_004098321.1 COGs: COG2409 drug exporter of the RND superfamily; InterPro IPR000731; KEGG: nca:Noca_0114 MmpL domain-containing protein; SPTR: uncharacterized protein; PFAM: MMPL family; TIGRFAM: transporter YP_004098322.1 InterPro IPR000835; KEGG: nca:Noca_0115 regulatory protein, MarR; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: uncharacterized protein; PFAM: MarR family YP_004098323.1 COGs: COG0146 N-methylhydantoinase B/acetone carboxylase subunit alpha; InterPro IPR003692; KEGG: cai:Caci_1877 hydantoinase B/oxoprolinase; PFAM: hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) B 2; PFAM: hydantoinase B/oxoprolinase YP_004098324.1 COGs: COG0145 N-methylhydantoinase A/acetone carboxylase subunit beta; InterPro IPR008040: IPR002821; KEGG: nca:Noca_1496 5-oxoprolinase (ATP-hydrolyzing); PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: N-methylhydantoinase (ATP-hydrolyzing) A 2; PFAM: hydantoinase/oxoprolinase; hydantoinase/oxoprolinase N-terminal region YP_004098325.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: nca:Noca_2939 response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004098326.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: nca:Noca_2938 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: ATP-binding region, ATPase domain protein domain protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004098327.1 COGs: COG4902 conserved hypothetical protein; InterPro IPR019243; KEGG: nml:Namu_2571 hypothetical protein; PFAM: protein of unknown function DUF2202; SPTR: uncharacterized protein; PFAM: Uncharacterized protein domain (DUF2202) YP_004098328.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: tfu:Tfu_3085 rhodanese-like protein; PFAM: rhodanese; SPTR: Rhodanese-like protein; PFAM: metallo-beta-lactamase superfamily; Rhodanese-like domain YP_004098329.1 COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: cai:Caci_1875 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: carbon-nitrogen hydrolase YP_004098330.1 COGs: COG3427 conserved hypothetical protein; InterPro IPR010419; KEGG: rop:ROP_32810 hypothetical protein; PFAM: carbon monoxide dehydrogenase subunit G; SPTR: uncharacterized protein; PFAM: carbon monoxide dehydrogenase subunit G (CoxG) YP_004098331.1 COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674: IPR008274; KEGG: svi:Svir_20920 xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: Probable dehydrogenase/oxidase; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain YP_004098332.1 COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterProIPR002346: IPR005107: IPR001041: IPR002888: IPR 006058: IPR016166; KEGG: tbi:Tbis_2230 molybdopterin dehydrogenase FAD-binding protein; PFAM: [2Fe-2S]-binding domain-containing protein; molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; ferredoxin; SPTR: carbon monoxide dehydrogenase, medium subunit, ; PFAM: 2Fe-2S iron-sulfur cluster binding domain; FAD binding domain in molybdopterin dehydrogenase; [2Fe-2S] binding domain; CO dehydrogenase flavoprotein C-terminal domain YP_004098333.1 COGs: COG2233 xanthine/uracil permease; InterPro IPR006043: IPR006042; KEGG: cai:Caci_1870 uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; SPTR: uracyl permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease YP_004098334.1 COGs: COG3835 Sugar diacid utilization regulator; KEGG: tcu:Tcur_2969 CdaR family transcriptional regulator; SPTR: transcriptional regulator YP_004098335.1 KEGG: tbi:Tbis_2233 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2877) YP_004098336.1 COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR009499; KEGG: nml:Namu_5358 protein of unknown function DUF1116; PFAM: protein of unknown function DUF1116; SPTR: uncharacterized protein; PFAM: CoA binding domain; CoA-ligase; protein of unknown function (DUF1116) YP_004098337.1 COGs: COG1278 Cold shock protein; InterPro IPR002059: IPR019844: IPR012156: IPR011129; KEGG: mva:Mvan_1040 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: Cold-shock DNA-binding protein family; PFAM: 'Cold-shock' DNA-binding domain YP_004098338.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: tcu:Tcur_0531 alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: 2-hydroxymuconic semialdehyde hydrolase; PFAM: alpha/beta hydrolase fold YP_004098339.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: tcu:Tcur_0539 betaine-aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: betaine-aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family YP_004098340.1 InterPro IPR004370: IPR018191; KEGG: nfa:nfa30440 isomerase; PFAM: 4-oxalocrotonate tautomerase; SPTR: isomerase; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme YP_004098341.1 COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mjl:Mjls_4208 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate hydrolase; PRIAM: 4-oxalocrotonate decarboxylase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family YP_004098342.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891: IPR012425: IPR017629; KEGG: tcu:Tcur_0536 4-hydroxy-2-oxovalerate aldolase; PFAM: pyruvate carboxyltransferase; DmpG communication domain protein; SPTR: 4-hydroxy-2-ketovalerate aldolase; TIGRFAM: 4-hydroxy-2-oxovalerate aldolase; PFAM: DmpG-like communication domain; HMGL-like; TIGRFAM: 4-hydroxy-2-oxovalerate aldolase YP_004098343.1 COGs: COG4569 acetaldehyde dehydrogenase (acetylating); InterPro IPR000534: IPR015426: IPR003361; KEGG: tcu:Tcur_0535 acetaldehyde dehydrogenase (acetylating); PFAM: acetaldehyde dehydrogenase; semialdehyde dehydrogenase NAD - binding; PRIAM: acetaldehyde dehydrogenase (acetylating); SPTR: acetaldehyde dehydrogenase (acetylating); TIGRFAM: acetaldehyde dehydrogenase (acetylating); PFAM: semialdehyde dehydrogenase, NAD binding domain; Prokaryotic acetaldehyde dehydrogenase, dimerisation; TIGRFAM: acetaldehyde dehydrogenase (acetylating) YP_004098344.1 COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: amd:AMED_8623 2-keto-4-pentenoate hydratase; PFAM: fumarylacetoacetate hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 2-oxopent-4-enoate hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase YP_004098345.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: tcu:Tcur_0533 IclR family transcriptional regulator; PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004098346.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: tcu:Tcur_0532 IclR family transcriptional regulator; PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004098347.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components; InterPro IPR001969; KEGG: dsh:Dshi_2543 binding protein; SPTR: ABC transporter periplasmic binding protein; PFAM: NMT1/THI5 like YP_004098348.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transporter permease; InterPro IPR000515; KEGG: sno:Snov_0215 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004098349.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transporter ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: sti:Sthe_1499 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004098350.1 COGs: COG3193 Uncharacterized protein possibly involved in utilization of glycolate and propanediol; InterPro IPR005624; KEGG: bts:Btus_0972 protein of unknown function DUF336; PFAM: protein of unknown function DUF336; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF336) YP_004098351.1 InterPro IPR004360: IPR000486; KEGG: tcu:Tcur_0529 catechol 2,3 dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Catechol 2,3 dioxygenase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: catechol 2,3 dioxygenase YP_004098352.1 InterPro IPR001041: IPR006058; KEGG: tcu:Tcur_0528 ferredoxin; PFAM: ferredoxin; SPTR: Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain YP_004098353.1 KEGG: bcv:Bcav_1237 hypothetical protein; SPTR: uncharacterized protein YP_004098354.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterPro IPR001140: IPR003439: IPR017940; KEGG: kfl:Kfla_5996 ABC transporter transmembrane region; PFAM: ABC transporter; ABC transporter transmembrane region; SPTR: ABC transporter transmembrane region; PFAM: ABC transporter transmembrane region; ABC transporter YP_004098355.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterPro IPR001140: IPR003439: IPR017940: IPR003593; KEGG: sro:Sros_8452 ABC-type multidrug transporter ATPase and permeases; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter, ATPase and permeases; PFAM: ABC transporter; ABC transporter transmembrane region YP_004098356.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027; KEGG: kfl:Kfla_2507 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004098357.1 InterPro IPR012312; KEGG: amd:AMED_4187 hemerythrin HHE cation binding protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin HHE cation binding domain protein; PFAM: hemerythrin HHE cation binding domain YP_004098358.1 COGs: COG0661 unusual protein kinase; InterPro IPR004147: IPR002575: IPR000719; KEGG: nca:Noca_4048 hypothetical protein; PFAM: ABC transporter; aminoglycoside phosphotransferase; SPTR: ABC transporter; PFAM: ABC1 family YP_004098359.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR020630: IPR020631: IPR000672; KEGG: nml:Namu_1278 methylenetetrahydrofolate dehydrogenase (NADP(+)); PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methenyltetrahydrofolate cyclohydrolase; SPTR: Bifunctional protein folD; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004098360.1 KEGG: kse:Ksed_07830 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3017) YP_004098361.1 InterPro IPR019606; KEGG: gob:Gobs_2813 lipoprotein LpqB, GerMN domain protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: Lipoprotein LpqB, GerMN domain protein; PFAM: sporulation and spore germination YP_004098362.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: kra:Krad_2109 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004098363.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: gob:Gobs_2815 transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: transcriptional regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004098364.1 InterPro IPR002645; KEGG: gob:Gobs_2816 anti-sigma-factor antagonist; SPTR: anti-sigma-factor antagonist YP_004098365.1 KEGG: svi:Svir_28050 ABC-type Fe3+-hydroxamate transport system, periplasmic component; SPTR: ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004098366.1 KEGG: kra:Krad_2107 anti-sigma-factor antagonist; SPTR: anti-sigma-factor antagonist YP_004098367.1 COGs: COG0039 malate/lactate dehydrogenase; InterPro IPR001236: IPR001252: IPR010945: IPR001557; KEGG: kfl:Kfla_1287 malate dehydrogenase; PFAM: lactate/malate dehydrogenase; SPTR: malate dehydrogenase; TIGRFAM: malate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase YP_004098368.1 COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: ach:Achl_0507 ketose-bisphosphate aldolase class-II; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Ketose-bisphosphate aldolase class-II; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004098369.1 COGs: COG2186 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: art:Arth_0271 GntR family transcriptional regulator; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004098370.1 COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: cdi:DIP2080 hypothetical protein; PFAM: type III effector Hrp-dependent outers; SPTR: YgbK domain protein; PFAM: protein of unknown function, DUF1537 YP_004098371.1 COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115: IPR002204; KEGG: art:Arth_0273 6-phosphogluconate dehydrogenase, NAD-binding; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; SPTR: 6-phosphogluconate dehydrogenase, NAD-binding; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase YP_004098372.1 COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: spe:Spro_1488 inner membrane permease YgbN; PFAM: gluconate transporter; SPTR: gluconate transporter; TIGRFAM: gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter YP_004098373.1 KEGG: gob:Gobs_2142 40-residue YVTN family beta-propeller repeat protein; SPTR: 40-residue YVTN family beta-propeller repeat protein YP_004098374.1 KEGG: mkm:Mkms_4774 hypothetical protein; SPTR: uncharacterized protein YP_004098375.1 InterPro IPR001434; KEGG: cbb:CLD_3502 hypothetical protein; PFAM: protein of unknown function DUF11; SPTR: membrane protein; TIGRFAM: conserved repeat domain protein; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain YP_004098376.1 KEGG: ach:Achl_3443 spore coat protein CotH; SPTR: Spore coat protein CotH YP_004098377.1 InterPro IPR013249; KEGG: mav:MAV_0606 hypothetical protein; PFAM: Sigma-70 region 4 type 2; SPTR: uncharacterized protein YP_004098378.1 KEGG: sro:Sros_3874 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF419) YP_004098379.1 COGs: COG0580 glycerol uptake facilitator and related permease (Major Intrinsic protein Family); InterPro IPR000425: IPR012269; KEGG: kse:Ksed_02220 MIP family channel protein; PFAM: major intrinsic protein; SPTR: Aquaporin Z; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_004098380.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: xce:Xcel_2582 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase family 2; PFAM: glycosyl transferase family 2 YP_004098381.1 KEGG: kse:Ksed_24700 GDSL-like lipase/acylhydrolase; SPTR: GDSL-like Lipase/acylhydrolase YP_004098382.1 COGs: COG4641 conserved hypothetical protein; InterPro IPR001173; KEGG: bfa:Bfae_27770 hypothetical protein; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase family 2 YP_004098383.1 KEGG: bvu:BVU_0885 glycosyl transferase family protein; SPTR: Nodulation protein Z (NodZ) YP_004098384.1 COGs: COG1484 DNA replication protein; InterPro IPR002611: IPR003593; KEGG: rha:RHA1_ro06914 insertion sequence ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: ATPase AAA; SPTR: Probable insertion sequence ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004098385.1 COGs: COG4584 transposase and inactivated derivatives; InterPro IPR001584; KEGG: dap:Dacet_2820 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: transposase; PFAM: Integrase core domain YP_004098386.1 KEGG: naz:Aazo_4909 group 1 glycosyl transferase; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004098387.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: slt:Slit_2887 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: glycosyltransferase; PFAM: glycosyl transferase family 2 YP_004098388.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: cgt:cgR_0436 hypothetical protein; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase, group 1 family; PFAM: glycosyl transferases group 1 YP_004098389.1 KEGG: bfa:Bfae_27760 hypothetical protein; SPTR: uncharacterized protein YP_004098390.1 InterPro IPR012480; KEGG: bcu:BCAH820_5363 hypothetical protein; PFAM: Heparinase II/III; SPTR: Conserved domain protein; manually curated; PFAM: Heparinase II/III-like protein YP_004098391.1 KEGG: psb:Psyr_0077 helix-turn-helix, fis-type; SPTR: Helix-turn-helix, Fis-type YP_004098392.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: msm:MSMEG_5398 ISMsm4, transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: ISMsm4, transposase; PFAM: transposase YP_004098393.1 KEGG: bfa:Bfae_27760 hypothetical protein; SPTR: uncharacterized protein YP_004098394.1 COGs: COG1134 ABC-type polysaccharide/polyol phosphate transporter ATPase component; InterPro IPR003439: IPR003593; KEGG: bfa:Bfae_27970 ABC-type polysaccharide/polyol phosphate transporter ATPase component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type polysaccharide/polyol phosphate transporter ATPase component; PFAM: ABC transporter YP_004098395.1 COGs: COG1682 ABC-type polysaccharide/polyol phosphate export systems permease; InterPro IPR013525; KEGG: bfa:Bfae_27980 ABC-type polysaccharide/polyol phosphate export systems, permease; PFAM: ABC transporter; SPTR: ABC transporter; PFAM: ABC transporter YP_004098396.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bfa:Bfae_27990 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004098397.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bfa:Bfae_28280 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004098398.1 COGs: COG1316 transcriptional regulator; InterPro IPR004474; KEGG: bfa:Bfae_09330 cell envelope-related function transcriptional attenuator common domain; PFAM: cell envelope-related transcriptional attenuator; SPTR: transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004098399.1 COGs: COG3835 Sugar diacid utilization regulator; KEGG: cai:Caci_0645 CdaR family transcriptional regulator; SPTR: CdaR family transcriptional regulator YP_004098400.1 COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: amd:AMED_2662 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: proline dehydrogenase; PFAM: Proline dehydrogenase YP_004098401.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR005931; KEGG: nca:Noca_1220 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: delta-1-pyrroline-5-carboxylate dehydrogenase 1; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 YP_004098402.1 KEGG: chl:Chy400_1862 cyclic nucleotide-binding protein; SPTR: Cyclic nucleotide-binding protein YP_004098403.1 KEGG: sna:Snas_2903 microbial collagenase; SPTR: Microbial collagenase YP_004098404.1 COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500: IPR011784; KEGG: kfl:Kfla_3324 sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: sulfate adenylyltransferase subunit 2; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, small subunit YP_004098405.1 COGs: COG2895 GTPase - sulfate adenylate transferase subunit 1; InterPro IPR000795: IPR004161: IPR011779; KEGG: xce:Xcel_0715 sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; PRIAM: sulfate adenylyltransferase; SPTR: sulfate adenylyltransferase subunit 1; TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: sulfate adenylyltransferase, large subunit; small GTP-binding protein domain; translation elongation factor TU YP_004098406.1 KEGG: bra:BRADO3423 hypothetical protein; SPTR: uncharacterized protein YP_004098407.1 COGs: COG4995 conserved hypothetical protein; KEGG: sro:Sros_3451 hypothetical protein; SPTR: uncharacterized protein YP_004098408.1 KEGG: hau:Haur_3056 PGAP1 family protein; SPTR: uncharacterized protein YP_004098409.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004098410.1 COGs: COG2313 Uncharacterized protein involved in pigment biosynthesis; InterPro IPR007342; KEGG: sen:SACE_1229 pigment biosynthetic protein; PFAM: indigoidine synthase A family protein; SPTR: Pseudouridine-5'-phosphate glycosidase; PFAM: indigoidine synthase A like protein YP_004098411.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sen:SACE_1230 sugar kinase, phosphofructokinase; PFAM: PfkB domain protein; SPTR: Sugar kinase, phosphofructokinase; PFAM: pfkB family carbohydrate kinase YP_004098412.1 COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: mab:MAB_2713 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004098413.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: cms:CMS_0628 dTDP-sugar reductase; PFAM: dTDP-4-dehydrorhamnose reductase; PRIAM: dTDP-4-dehydrorhamnose reductase; SPTR: DTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase YP_004098414.1 COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509: IPR005888; KEGG: xce:Xcel_2563 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase YP_004098415.1 KEGG: msm:MSMEG_4735 hypothetical protein; SPTR: uncharacterized protein YP_004098416.1 COGs: COG2244 membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: ara:Arad_3073 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein YP_004098417.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: kra:Krad_3678 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase family 2; PFAM: glycosyl transferase family 2 YP_004098418.1 COGs: COG5039 Exopolysaccharide biosynthesis protein; KEGG: fre:Franean1_0750 polysaccharide pyruvyl transferase; SPTR: polysaccharide pyruvyl transferase YP_004098419.1 COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835: IPR005907; KEGG: cfl:Cfla_2349 glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; SPTR: glucose-1-phosphate thymidylyltransferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form YP_004098420.1 COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888; KEGG: xce:Xcel_2560 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase YP_004098421.1 COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867: IPR000106; KEGG: aau:AAur_3227 low molecular weight phosphotyrosine protein phosphatase; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: Low molecular weight phosphotyrosine protein phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_004098422.1 KEGG: rmu:RMDY18_15760 methyl-accepting chemotaxis protein; SPTR: uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD) YP_004098423.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: rmu:RMDY18_15770 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: Group 1 glycosyl transferase; PFAM: glycosyl transferases group 1 YP_004098424.1 KEGG: aau:AAur_4128 hypothetical protein; SPTR: uncharacterized protein YP_004098425.1 KEGG: art:Arth_3222 hypothetical protein; SPTR: uncharacterized protein YP_004098426.1 KEGG: rmu:RMDY18_15750 dioxygenase related to 2-nitropropane dioxygenase; SPTR: uncharacterized protein YP_004098427.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856: IPR005702; KEGG: cmi:CMM_0908 tyrosine-protein kinase; PFAM: lipopolysaccharide biosynthesis protein; PRIAM: non-specific protein-tyrosine kinase; SPTR: tyrosine-protein kinase; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family YP_004098428.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296: IPR001173; KEGG: rrs:RoseRS_3120 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; glycosyl transferase family 2; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1; glycosyl transferase family 2 YP_004098429.1 KEGG: pfs:PFLU2073 hypothetical protein; SPTR: O-antigen polymerase; PFAM: O-antigen ligase YP_004098430.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: rxy:Rxyl_0689 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004098431.1 KEGG: hmo:HM1_1182 glycosyl transferase, group 1 family protein, SPTR: glycosyl transferase, group 1 family protein YP_004098432.1 KEGG: psl:Psta_1298 ExoV-like protein; SPTR: GumL protein; PFAM: polysaccharide pyruvyl transferase YP_004098433.1 KEGG: cmi:CMM_0909 hypothetical protein; SPTR: uncharacterized protein YP_004098434.1 COGs: COG1316 transcriptional regulator; InterPro IPR004474; KEGG: tcu:Tcur_4461 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004098435.1 KEGG: azc:AZC_4062 hypothetical protein; SPTR: uncharacterized protein YP_004098436.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: mjl:Mjls_1346 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004098437.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: afw:Anae109_1425 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase, group 1; PFAM: glycosyl transferases group 1 YP_004098438.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: rce:RC1_2536 glycosyl transferase, group 1 family protein; PFAM: glycosyl transferase group 1; SPTR: Possible mannosyltransferase II; PFAM: glycosyl transferases group 1 YP_004098439.1 InterPro IPR017909: IPR006311; KEGG: kse:Ksed_18940 hypothetical protein; SPTR: uncharacterized protein YP_004098440.1 KEGG: kse:Ksed_16960 hypothetical protein; SPTR: uncharacterized protein; PFAM: methylamine utilisation protein MauE YP_004098441.1 COGs: COG0708 exonuclease III; InterPro IPR005135: IPR004808; KEGG: cfl:Cfla_2498 exodeoxyribonuclease III Xth; PFAM: endonuclease/exonuclease/phosphatase; SPTR: exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; PFAM: endonuclease/exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_004098442.1 COGs: COG0180 tryptophanyl-tRNA synthetase; InterPro IPR002305: IPR001412: IPR002306; KEGG: cfl:Cfla_1010 tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: tryptophan--tRNA ligase; SPTR: tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_004098443.1 COGs: COG1514 2'-5' RNA ligase; InterPro IPR014051; KEGG: kfl:Kfla_1321 phosphoesterase HXTX; PFAM: phosphoesterase HXTX; SPTR: secreted protein; PFAM: 2',5' RNA ligase family YP_004098444.1 COGs: COG1295 membrane protein; InterPro IPR004664: IPR019825; KEGG: kra:Krad_3967 ribonuclease BN; PFAM: ribonuclease BN; SPTR: membrane protein ribonuclease BN-like family protein; PFAM: ribonuclease BN-like family; TIGRFAM: ribonuclease YP_004098445.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967: IPR003342: IPR018493: IPR018044; KEGG: tbi:Tbis_0672 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; glycosyl transferase family 39; SPTR: Probable penicillin-binding protein dacb1 (D-alanyl-d-alaninecarboxypeptidase) (Dd-peptidase) (Dd-carboxypeptidase); PFAM: D-alanyl-D-alanine carboxypeptidase; Dolichyl-phosphate-mannose-protein mannosyltransferase YP_004098446.1 COGs: COG0479 succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017900: IPR017896: IPR004489; KEGG: nca:Noca_3553 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; SPTR: succinate dehydrogenase; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_004098447.1 COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: nca:Noca_3552 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: succinate dehydrogenase; SPTR: succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup YP_004098448.1 InterPro IPR011138; KEGG: nca:Noca_3551 succinate dehydrogenase subunit C; SPTR: succinate dehydrogenase, cytochrome b558 subunit; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family YP_004098449.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: kse:Ksed_07870 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase; PFAM: glycosyl transferases group 1 YP_004098450.1 COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: xce:Xcel_2850 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004098451.1 COGs: COG0836 mannose-1-phosphate guanylyltransferase; InterPro IPR005835: IPR001538; KEGG: nca:Noca_1407 mannose-1-phosphate guanylyltransferase (GDP); PFAM: nucleotidyl transferase; mannose-6-phosphate isomerase type II; PRIAM: mannose-1-phosphate guanylyltransferase; SPTR: mannose-1-phosphate guanylyltransferase; PFAM: nucleotidyl transferase; mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_004098452.1 COGs: COG3559 exporter of polyketide antibiotics; KEGG: kfl:Kfla_5153 exporter of polyketide antibiotics-like protein; SPTR: ABC transporter YP_004098453.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: nca:Noca_2559 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter YP_004098454.1 COGs: COG1884 methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099: IPR006098; KEGG: cai:Caci_0774 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: methylmalonyl-CoA mutase; SPTR: methylmalonyl CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain YP_004098455.1 COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933: IPR011650: IPR010168: IPR017439; KEGG: nca:Noca_3542 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase YP_004098456.1 COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: sro:Sros_1269 ABC-type transporter substrate-binding protein; PFAM: basic membrane lipoprotein; SPTR: ABC-type transporter substrate-binding protein; PFAM: Basic membrane protein YP_004098457.1 COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR003439: IPR017871: IPR003593; KEGG: nca:Noca_3540 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004098458.1 COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: nca:Noca_3539 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component YP_004098459.1 COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: nca:Noca_3538 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component YP_004098460.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125: IPR016192: IPR006262; KEGG: gob:Gobs_4399 cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_004098461.1 COGs: COG0213 thymidine phosphorylase; InterProIPR017459: IPR000312: IPR013102: IPR017872: IPR 018090: IPR000053; KEGG: bcv:Bcav_2940 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: thymidine phosphorylase; SPTR: thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; glycosyl transferase family, a/b domain; glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase YP_004098462.1 KEGG: sro:Sros_1278 hypothetical protein; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004098463.1 COGs: COG1816 adenosine deaminase; InterPro IPR001365: IPR006330; KEGG: sro:Sros_1279 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: adenosine deaminase; SPTR: adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; TIGRFAM: adenosine deaminase YP_004098464.1 COGs: COG0572 Uridine kinase; KEGG: kse:Ksed_08140 uridine kinase; SPTR: Uridine kinase; PFAM: phosphoribulokinase / Uridine kinase family YP_004098465.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: bcv:Bcav_0211 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family YP_004098466.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: bcv:Bcav_0209 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family YP_004098467.1 COGs: COG0274 deoxyribose-phosphate aldolase; InterPro IPR002915: IPR011343; KEGG: gob:Gobs_4390 deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: deoxyribose-phosphate aldolase; SPTR: deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_004098468.1 KEGG: bcv:Bcav_1119 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2581) YP_004098469.1 COGs: COG1109 phosphomannomutase; InterProIPR005844: IPR005845: IPR005846: IPR005843: IPR 016066; KEGG: kse:Ksed_08160 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004098470.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845: IPR011268: IPR011269; KEGG: kse:Ksed_08170 purine nucleotide phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: Purine nucleoside phosphorylase; TIGRFAM: purine nucleotide phosphorylase; inosine guanosine and xanthosine phosphorylase family; PFAM: phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family; purine nucleotide phosphorylase YP_004098471.1 COGs: COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027: IPR004099: IPR000815; KEGG: nca:Noca_3517 flavoprotein disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004098472.1 KEGG: cfl:Cfla_0613 NLP/P60 protein; SPTR: uncharacterized protein YP_004098473.1 COGs: COG4770 acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, subunit alpha; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: acyl-CoA carboxylase, subunit alpha; PFAM: carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme YP_004098474.1 COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: tcu:Tcur_1587 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family YP_004098475.1 KEGG: mlu:Mlut_01340 hypothetical protein; SPTR: uncharacterized protein YP_004098476.1 COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: mlu:Mlut_10710 SufE protein probably involved in Fe-S center assembly; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated domain protein; PFAM: Fe-S metabolism associated domain YP_004098477.1 COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: ach:Achl_1659 rhodanese domain protein; PFAM: rhodanese; PRIAM: thiosulfate sulfurtransferase; SMART: rhodanese; SPTR: rhodanese; PFAM: Rhodanese-like domain YP_004098478.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551: IPR015358; KEGG: kfl:Kfla_1417 transcriptional regulator, MerR family; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR; SPTR: MerR-family transcriptional regulator; PFAM: MerR, DNA binding; MerR family regulatory protein YP_004098479.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: kse:Ksed_08210 butyryl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: FadE19; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004098480.1 COGs: COG4799 acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022: IPR011762: IPR011763; KEGG: kse:Ksed_08220 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); PFAM: carboxyl transferase; SPTR: YngE; PFAM: carboxyl transferase domain YP_004098481.1 KEGG: cfl:Cfla_1002 integral membrane protein; SPTR: integral membrane protein YP_004098482.1 COGs: COG0424 nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: ske:Sked_25490 MAF protein; PFAM: Maf family protein; SPTR: Maf-like protein Sked_25490; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein YP_004098483.1 COGs: COG4805 conserved hypothetical protein; InterPro IPR010281; KEGG: kse:Ksed_08300 hypothetical protein; PFAM: protein of unknown function DUF885; SPTR: Uncharacterized conserved protein; PFAM: Bacterial protein of unknown function (DUF885) YP_004098484.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR008271: IPR000719: IPR 020635: IPR002290; KEGG: bcv:Bcav_1908 serine/threonine protein kinase with PASTA sensor(s); PFAM: serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: serine/threonine protein kinase with PASTA sensor(S); PFAM: protein kinase domain YP_004098485.1 KEGG: car:cauri_0505 hypothetical protein; SPTR: transcriptional repressor protein YP_004098486.1 COGs: COG0370 Fe2+ transporter protein B; InterProIPR002917: IPR011619: IPR011642: IPR011640: IPR 003373: IPR006073; KEGG: cur:cur_1150 ferrous iron transporter; PFAM: GTP-binding protein HSR1-related; Ferrous iron transporter B domain-containing protein; nucleoside recognition domain protein; Ferrous iron transport B domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: ferrous iron transporter B; PFAM: Ferrous iron transporter B; Ferrous iron transporter B C terminus; nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain YP_004098487.1 KEGG: car:cauri_0507 hypothetical protein; SPTR: uncharacterized protein; PFAM: FeoA domain YP_004098488.1 KEGG: kra:Krad_3990 hypothetical protein; SPTR: uncharacterized protein YP_004098489.1 COGs: COG4799 acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022: IPR011762: IPR011763: IPR000438; KEGG: kfl:Kfla_1439 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Propionyl-CoA carboxylase complex B subunit; PFAM: carboxyl transferase domain YP_004098490.1 COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004408: IPR004143: IPR003142; KEGG: tfu:Tfu_2553 biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; SPTR: Biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region YP_004098491.1 COGs: COG2114 adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: art:Arth_1285 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; PRIAM: adenylate cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylyl cyclase class-3/4/guanylyl cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain YP_004098492.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR001753; KEGG: kse:Ksed_08370 short chain enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: Short chain enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase family YP_004098493.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: scb:SCAB_54821 two-component system reponse regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004098494.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR003661: IPR003594: IPR005467; KEGG: cfl:Cfla_2388 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: two-component system sensor kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004098495.1 InterPro IPR007267; KEGG: ckp:ckrop_0691 hypothetical protein; PFAM: GtrA family protein; SPTR: membrane protein; PFAM: GtrA-like protein YP_004098496.1 COGs: COG0026 phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); InterPro IPR005875: IPR003135: IPR011761; KEGG: sgr:SGR_4477 phosphoribosylaminoimidazole carboxylase ATPase; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; PRIAM: phosphoribosylaminoimidazole carboxylase; SPTR: phosphoribosylaminoimidazole carboxylase ATPase PurK; TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase; PFAM: ATP-grasp domain; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurK protein YP_004098497.1 COGs: COG0041 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: xce:Xcel_2596 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: phosphoribosylaminoimidazole carboxylase; SPTR: phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_004098498.1 COGs: COG1832 CoA-binding protein; KEGG: bcv:Bcav_1164 CoA-binding protein; SPTR: uncharacterized protein YP_004098499.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019952: IPR016048; KEGG: ske:Sked_29280 flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like, subgroup; SPTR: uncharacterized protein; TIGRFAM: F420-dependent oxidoreductase; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable F420-dependent oxidoreductase, Rv1855c family YP_004098500.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: nwi:Nwi_2393 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004098501.1 COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329; KEGG: tin:Tint_2653 N-acylneuraminate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; SPTR: acylneuraminate cytidylyltransferase; PFAM: Cytidylyltransferase YP_004098502.1 COGs: COG0673 dehydrogenase and related protein; KEGG: net:Neut_1547 oxidoreductase domain-containing protein; SPTR: oxidoreductase domain protein YP_004098503.1 InterPro IPR000812: IPR002797; KEGG: cwo:Cwoe_0093 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein YP_004098504.1 KEGG: tmt:Tmath_0720 capsule polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: capsule polysaccharide biosynthesis protein YP_004098505.1 COGs: COG1045 serine acetyltransferase; InterPro IPR018357: IPR001451; KEGG: gur:Gura_1700 serine acetyltransferase-like protein; PFAM: transferase; SPTR: Pilin glycosylation protein; TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family YP_004098506.1 COGs: COG2089 Sialic acid synthase; InterPro IPR013132: IPR013974; KEGG: mag:amb0080 sialic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: Sialic acid synthase; PFAM: SAF domain; NeuB family YP_004098507.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR020004: IPR003331; KEGG: hna:Hneap_0630 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; PFAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; TIGRFAM: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing YP_004098508.1 COGs: COG1208 nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/subunit epsilons (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR000644: IPR005835; KEGG: mag:amb0085 nucleoside-diphosphate-sugar pyrophosphorylase; PFAM: nucleotidyl transferase; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: nucleoside-diphosphate-sugar pyrophosphorylase; PFAM: nucleotidyl transferase; CBS domain YP_004098509.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: dra:DR_0711 UDP-glucose 4-epimerase, PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, ; PFAM: NAD dependent epimerase/dehydratase family YP_004098510.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: afw:Anae109_2633 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_004098511.1 COGs: COG0075 serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: bvi:Bcep1808_3397 aminotransferase, class V; PFAM: aminotransferase class V; SPTR: Aminotransferase, class V; PFAM: Aminotransferase class-V YP_004098512.1 KEGG: kse:Ksed_01640 hypothetical protein; SPTR: uncharacterized protein YP_004098513.1 KEGG: gob:Gobs_4383 hypothetical protein; SPTR: uncharacterized protein YP_004098514.1 COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: sgr:SGR_456 hypothetical protein; PFAM: peptidase U61 LD-carboxypeptidase A; SPTR: uncharacterized protein; PFAM: LD-carboxypeptidase YP_004098515.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235: IPR000277; KEGG: kfl:Kfla_1576 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_004098516.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006091: IPR006090; KEGG: tfu:Tfu_1647 acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004098517.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: kse:Ksed_08480 glycosyl transferase; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase; PFAM: glycosyl transferase family 2 YP_004098518.1 COGs: COG2057 acyl CoA:acetate/3-ketoacid CoA transferase subunit beta; InterPro IPR012791: IPR004164: IPR004165; KEGG: nca:Noca_0331 butyryl-CoA:acetate CoA transferase; PFAM: coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: Butyryl-CoA:acetate CoA transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit YP_004098519.1 COGs: COG1788 acyl CoA:acetate/3-ketoacid CoA transferase subunit alpha; InterPro IPR012792: IPR004163: IPR004165; KEGG: nca:Noca_0330 3-oxoacid CoA-transferase, subunit alpha; PFAM: coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: 3-oxoadipate CoA-transferase subunit A; TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha YP_004098520.1 InterPro IPR002477; KEGG: sna:Snas_2804 peptidoglycan-binding protein; PFAM: peptidoglycan-binding domain 1 protein; SPTR: uncharacterized protein; PFAM: peptidoglycan binding domain YP_004098521.1 InterPro IPR017523; KEGG: kse:Ksed_08510 conserved hypothetical protein TIGR03089; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR03089 YP_004098522.1 COGs: COG1316 transcriptional regulator; InterPro IPR004474; KEGG: kse:Ksed_08470 cell envelope-related function transcriptional attenuator common domain protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004098523.1 KEGG: kra:Krad_3898 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2304) YP_004098524.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfa:Bfae_20890 glycosyl transferase; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase; manually curated; PFAM: glycosyl transferase family 2 YP_004098525.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: kra:Krad_3865 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase; PFAM: glycosyl transferases group 1 YP_004098526.1 KEGG: tcu:Tcur_4083 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104) YP_004098527.1 InterPro IPR004378; KEGG: mav:MAV_0120 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: Domain of unknown function (DUF385); TIGRFAM: deazaflavin-dependent nitroreductase family protein YP_004098528.1 InterPro IPR006311; KEGG: nca:Noca_1408 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3105) YP_004098529.1 COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; KEGG: nca:Noca_2841 hypothetical protein; SPTR: uncharacterized protein YP_004098530.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR019793: IPR000253: IPR002543: IPR003593; KEGG: tcu:Tcur_4147 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; Forkhead-associated protein; SMART: Forkhead-associated protein; AAA ATPase; SPTR: cell divisionFtsK/SpoIIIE; PFAM: FtsK/SpoIIIE family; FHA domain YP_004098531.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: fre:Franean1_5826 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: type II/type IV pathway secretion protein; PFAM: type II/IV secretion system protein YP_004098532.1 COGs: COG4965 Flp pilus assembly protein TadB; InterPro IPR018076; KEGG: xce:Xcel_1032 type II secretion system protein; PFAM: type II secretion system F domain; SPTR: uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain YP_004098533.1 COGs: COG4965 Flp pilus assembly protein TadB; InterPro IPR018076; KEGG: kse:Ksed_10340 Flp pilus assembly protein TadB; PFAM: type II secretion system F domain; SPTR: uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain YP_004098534.1 KEGG: kse:Ksed_10350 hypothetical protein; SPTR: uncharacterized protein YP_004098535.1 KEGG: bcv:Bcav_2787 TadE family protein; SPTR: uncharacterized protein; PFAM: TadE-like protein YP_004098536.1 KEGG: kra:Krad_3785 TadE family protein; SPTR: uncharacterized protein YP_004098537.1 KEGG: kra:Krad_3784 hypothetical protein; SPTR: uncharacterized protein YP_004098538.1 KEGG: kfl:Kfla_4685 hypothetical protein; SPTR: uncharacterized protein YP_004098539.1 COGs: COG1186 protein chain release factor B; InterPro IPR004374: IPR020853: IPR000352: IPR005139; KEGG: kse:Ksed_10410 peptide chain release factor 2; PFAM: class I peptide chain release factor; PCRF domain protein; SPTR: peptide chain release factor 2; TIGRFAM: peptide chain release factor 2; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_004098540.1 COGs: COG2884 ATPase involved in cell division; InterPro IPR005286: IPR017871: IPR003439: IPR003593; KEGG: cai:Caci_1407 cell division ATP-binding protein FtsE; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ATPase; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE YP_004098541.1 COGs: COG2177 cell division protein; InterPro IPR003838; KEGG: aau:AAur_2655 cell division protein (FtsX); PFAM: protein of unknown function DUF214; SPTR: cell division protein; PFAM: Predicted permease YP_004098542.1 COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: cfl:Cfla_1246 peptidase M23; PFAM: peptidase M23; SPTR: uncharacterized protein; PFAM: peptidase family M23 YP_004098543.1 COGs: COG0691 tmRNA-binding protein; InterPro IPR000037: IPR020081; KEGG: kra:Krad_3779 SsrA-binding protein; PFAM: SmpB protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004098544.1 InterPro IPR018702; KEGG: bcv:Bcav_2765 hypothetical protein; PFAM: protein of unknown function DUF2207, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2207) YP_004098545.1 COGs: COG1038 pyruvate carboxylase; InterProIPR005930: IPR000634: IPR005479: IPR005481: IPR 005482: IPR000891: IPR003379: IPR000089: IPR011761: IPR011764; KEGG: gob:Gobs_1751 pyruvate carboxylase; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; pyruvate carboxyltransferase; Conserved carboxylase region; biotin/lipoyl attachment domain-containing protein; SPTR: pyruvate carboxylase; TIGRFAM: pyruvate carboxylase; tmRNA as predicted by Rfam (RF00023), score 168.01; PFAM: carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; HMGL-like; carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme; Conserved carboxylase domain; TIGRFAM: pyruvate carboxylase YP_004098546.1 KEGG: msv:Mesil_2867 serine/threonine protein kinase; SPTR: cytochrome C oxidase subunit 2 YP_004098547.1 COGs: COG3118 thioredoxin domain-containing protein; InterProIPR005746: IPR006662: IPR017937: IPR013766: IPR 017936; KEGG: ske:Sked_24970 thioredoxin; PFAM: thioredoxin domain-containing protein; SPTR: thioredoxin; TIGRFAM: thioredoxin; PFAM: thioredoxin; TIGRFAM: thioredoxin YP_004098548.1 COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: tpr:Tpau_2768 protein of unknown function DUF541; PFAM: protein of unknown function DUF541; SPTR: Outer membrane protein, 28kDa; PFAM: protein of unknown function (DUF541) YP_004098549.1 InterPro IPR006976; KEGG: mlu:Mlut_19790 hypothetical protein; PFAM: VanZ family protein; SPTR: uncharacterized protein; PFAM: VanZ like family YP_004098550.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR014021: IPR 014014; KEGG: kse:Ksed_10490 DNA/RNA helicase, superfamily II; PFAM: DEAD/DEAH box helicase domain protein; helicase; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase; manually curated; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004098551.1 COGs: COG1678 transcriptional regulator protein; InterPro IPR003774; KEGG: kra:Krad_3774 hypothetical protein; PFAM: protein of unknown function DUF179; SPTR: UPF0301 protein Krad_3774; PFAM: Uncharacterized ACR, COG1678 YP_004098552.1 COGs: COG0796 glutamate racemase; InterPro IPR018187: IPR015942; KEGG: scb:SCAB_83081 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: glutamate racemase; SPTR: glutamate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_004098553.1 KEGG: aau:AAur_2578 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3039) YP_004098554.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935: IPR014001: IPR014021; KEGG: kse:Ksed_10520 DNA/RNA helicase, superfamily II; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: uncharacterized protein; manually curated; PFAM: type III restriction enzyme, res subunit YP_004098555.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterProIPR006311: IPR006179: IPR022272: IPR004843: IPR 008334: IPR017909; KEGG: nca:Noca_1299 5'-nucleotidase domain-containing protein; PFAM: 5'-nucleotidase domain-containing protein; metallophosphoesterase; PRIAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; SPTR: 5'-nucleotidase domain protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain YP_004098556.1 COGs: COG1522 transcriptional regulators; InterPro IPR019887: IPR019888; KEGG: cai:Caci_1485 transcriptional regulator, AsnC family; PFAM: transcription regulator AsnC-type-like; SMART: transcription regulator AsnC-type; SPTR: asnC-family transcriptional regulator; PFAM: AsnC family YP_004098557.1 COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR005956: IPR004360; KEGG: rha:RHA1_ro03170 4-hydroxyphenylpyruvate dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase YP_004098558.1 InterPro IPR018929: IPR010432; KEGG: kra:Krad_3769 RDD domain containing protein; PFAM: RDD domain containing protein; protein of unknown function DUF2510; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2510); RDD family YP_004098559.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR004638: IPR001411: IPR011701; KEGG: stp:Strop_1086 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: transporter; TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter EmrB/QacA subfamily YP_004098560.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR005959: IPR015377: IPR002529; KEGG: kse:Ksed_10630 fumarylacetoacetate hydrolase; PFAM: Domain of unknown function DUF1969; fumarylacetoacetate hydrolase; PRIAM: Fumarylacetoacetase; SPTR: fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: Domain of unknown function (DUF1969); Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: fumarylacetoacetase YP_004098561.1 KEGG: kse:Ksed_10640 hypothetical protein; SPTR: uncharacterized protein YP_004098562.1 COGs: COG3508 Homogentisate 1 2-dioxygenase; InterPro IPR005708; KEGG: kse:Ksed_10650 homogentisate 1,2-dioxygenase; PFAM: homogentisate 12-dioxygenase; SPTR: dioxygenase; PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase YP_004098563.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: nca:Noca_1292 regulatory proteins, IclR; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain YP_004098564.1 COGs: COG1335 amidase related to nicotinamidase; InterPro IPR000868; KEGG: ami:Amir_1003 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family YP_004098565.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR006405: IPR007229: IPR015977; KEGG: nca:Noca_1307 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: nicotinate phosphoribosyltransferase YP_004098566.1 COGs: COG2127 conserved hypothetical protein; InterPro IPR003769; KEGG: sma:SAV_5159 ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS; SPTR: uncharacterized protein; PFAM: ATP-dependent Clp protease adaptor protein ClpS YP_004098567.1 InterPro IPR018561; KEGG: bcv:Bcav_2740 hypothetical protein; PFAM: Domain of unknown function DUF2017; SPTR: ATP-dependent Clp protease adaptor protein ClpS; PFAM: Domain of unknown function (DUF2017) YP_004098568.1 COGs: COG1234 metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: kse:Ksed_09930 metal-dependent hydrolase, beta-lactamase superfamily III; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily YP_004098569.1 COGs: COG0689 RNase PH; InterPro IPR002381: IPR018336: IPR001247: IPR015847; KEGG: kra:Krad_3763 ribonuclease PH; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: ribonuclease PH; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; TIGRFAM: ribonuclease PH YP_004098570.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR002637: IPR020922; KEGG: sgr:SGR_4640 deoxyribonucleotide triphosphate pyrophosphatase; PFAM: Ham1 family protein; SPTR: deoxyribonucleotide triphosphate pyrophosphatase; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_004098571.1 COGs: COG2041 Sulfite oxidase; InterPro IPR000572: IPR005066; KEGG: art:Arth_1443 oxidoreductase, molybdopterin binding; PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; SPTR: oxidoreductase, molybdopterin binding; PFAM: Mo-co oxidoreductase dimerisation domain; oxidoreductase molybdopterin binding domain YP_004098572.1 KEGG: kse:Ksed_00460 HNH endonuclease; SPTR: HNH endonuclease YP_004098573.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006175; KEGG: dra:DR_0033 hypothetical protein; PFAM: endoribonuclease L-PSP; SPTR: uncharacterized protein; PFAM: endoribonuclease L-PSP YP_004098574.1 COGs: COG1225 peroxiredoxin; InterPro IPR000866: IPR017936; KEGG: nca:Noca_1326 redoxin domain-containing protein; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; SPTR: redoxin; PFAM: AhpC/TSA family YP_004098575.1 KEGG: kra:Krad_3756 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3618) YP_004098576.1 COGs: COG0234 Co-chaperonin GroES (HSP10); InterPro IPR001476: IPR020818; KEGG: kfl:Kfla_1859 chaperonin Cpn10; PFAM: chaperonin Cpn10; SPTR: 10 kDa chaperonin; manually curated; PFAM: chaperonin 10 Kd subunit YP_004098577.1 KEGG: ses:SARI_04130 hypothetical protein; SPTR: uncharacterized protein YP_004098578.1 COGs: COG1949 oligoribonuclease (3'->5' exoribonuclease); InterPro IPR013520: IPR006055; KEGG: scb:SCAB_57821 oligoribonuclease; PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; SPTR: oligoribonuclease; PFAM: exonuclease YP_004098579.1 COGs: COG2339 membrane protein; KEGG: kse:Ksed_08850 predicted membrane protein; SPTR: membrane protein YP_004098580.1 KEGG: kse:Ksed_08870 hypothetical protein; SPTR: ABC transporter; PFAM: Dynamin family YP_004098581.1 KEGG: kse:Ksed_08880 predicted GTPase; SPTR: ABC transporter; PFAM: Dynamin family YP_004098582.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344: IPR000424; KEGG: fra:Francci3_1145 single-stranded DNA-binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004098583.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR017871: IPR003439: IPR003593; KEGG: cfl:Cfla_1352 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; TIGRFAM: ATP-binding cassette protein, ChvD family YP_004098584.1 COGs: COG2072 flavoprotein involved in K+ transport; InterPro IPR000103: IPR013027: IPR006076; KEGG: ach:Achl_2135 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004098585.1 COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524: IPR004839; KEGG: kfl:Kfla_5648 GntR family transcriptional regulator protein; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator protein; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II YP_004098586.1 COGs: COG2364 membrane protein; InterPro IPR003740; KEGG: bcv:Bcav_3925 protein of unknown function DUF161; PFAM: protein of unknown function DUF161; SPTR: integral membrane protein; PFAM: Uncharacterized BCR, YitT family COG1284 YP_004098587.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019952: IPR016048; KEGG: bcv:Bcav_4065 luciferase-like monooxygenase; PFAM: Luciferase-like, subgroup; SPTR: uncharacterized protein; TIGRFAM: F420-dependent oxidoreductase; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable F420-dependent oxidoreductase, Rv1855c family YP_004098588.1 KEGG: nca:Noca_3344 hypothetical protein; SPTR: uncharacterized protein YP_004098589.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: sma:SAV_6602 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004098590.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006091: IPR006090; KEGG: nca:Noca_0271 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004098591.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904; KEGG: amd:AMED_3126 3-oxoacyl-[acyl-carrier-protein] reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004098592.1 COGs: COG1523 type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR011837: IPR004193: IPR006047: IPR006589; KEGG: cfl:Cfla_1743 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: alpha amylase, catalytic domain; carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glycogen debranching enzyme GlgX YP_004098593.1 COGs: COG3280 Maltooligosyl trehalose synthase; InterPro IPR012767: IPR006047: IPR006589; KEGG: kra:Krad_3074 maltooligosyl trehalose synthase; PFAM: alpha amylase catalytic region; PRIAM: (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase; SMART: alpha amylase catalytic sub domain; SPTR: Malto-oligosyltrehalose synthase; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose synthase YP_004098594.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR012768: IPR004193: IPR006047: IPR006589; KEGG: kfl:Kfla_0738 malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: Malto-oligosyltrehalose trehalohydrolase; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose trehalohydrolase YP_004098595.1 COGs: COG1946 acyl-CoA thioesterase; InterPro IPR003703; KEGG: aau:AAur_2394 acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; PRIAM: Choloyl-CoA hydrolase; SPTR: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; TIGRFAM: acyl-CoA thioesterase II YP_004098596.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR018329: IPR002464: IPR011545: IPR001650: IPR 014001: IPR014021; KEGG: kse:Ksed_06850 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase; helicase; SMART: helicase; DEAD-like helicase; SPTR: ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family YP_004098597.1 COGs: COG0824 thioesterase; InterPro IPR006683; KEGG: kse:Ksed_08950 predicted thioesterase; PFAM: thioesterase superfamily protein; SPTR: uncharacterized protein; PFAM: thioesterase superfamily YP_004098598.1 KEGG: kse:Ksed_08960 hypothetical protein; SPTR: uncharacterized protein YP_004098599.1 COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: kfl:Kfla_3595 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase family YP_004098600.1 COGs: COG0366 glycosidase; InterPro IPR006047: IPR006589; KEGG: cfl:Cfla_2176 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: alpha-glucosidase; PFAM: alpha amylase, catalytic domain YP_004098601.1 KEGG: art:Arth_3707 hypothetical protein; SPTR: uncharacterized protein YP_004098602.1 COGs: COG2346 Truncated hemoglobins; InterPro IPR019795: IPR001486; KEGG: bcv:Bcav_2637 globin; PFAM: globin; SPTR: Globin; PFAM: Bacterial-like globin YP_004098603.1 COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: kra:Krad_3531 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: Small-conductance mechanosensitive channel; PFAM: Mechanosensitive ion channel YP_004098604.1 COGs: COG0308 Aminopeptidase N; InterPro IPR012778: IPR014782: IPR005829; KEGG: kse:Ksed_09020 aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; PRIAM: membrane alanyl aminopeptidase; SPTR: Aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Domain of unknown function (DUF3358); peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type YP_004098605.1 KEGG: jde:Jden_0944 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: DSBA-like thioredoxin domain YP_004098606.1 COGs: COG0698 ribose 5-phosphate isomerase RpiB; InterPro IPR011860: IPR003500; KEGG: kse:Ksed_09040 ribose 5-phosphate isomerase; PFAM: ribose/galactose isomerase; SPTR: ribose 5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004098607.1 COGs: COG2208 serine phosphatase RsbU regulator of sigma subunit; InterPro IPR018486: IPR010822: IPR001932; KEGG: nca:Noca_3481 stage II sporulation E family protein; PFAM: stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: integral membrane protein; PFAM: stage II sporulation protein E (SpoIIE) YP_004098608.1 COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; InterPro IPR003358; KEGG: sna:Snas_0303 tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; SPTR: Possible S-adenosylmethionine-dependent methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase YP_004098609.1 COGs: COG1071 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit alpha; InterPro IPR001017; KEGG: tbi:Tbis_1749 pyruvate dehydrogenase; PFAM: dehydrogenase E1 component; PRIAM: pyruvate dehydrogenase (acetyl-transferring); SPTR: pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component YP_004098610.1 COGs: COG0022 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit beta; InterPro IPR005475: IPR005476; KEGG: nca:Noca_3770 transketolase, central region; PFAM: transketolase; transketolase domain-containing protein; SPTR: transketolase, central region; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain YP_004098611.1 InterPro IPR003016: IPR000089; KEGG: tbi:Tbis_1751 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: Biotin/lipoyl attachment domain-containing protein; PFAM: Biotin-requiring enzyme YP_004098612.1 KEGG: kfl:Kfla_2978 hypothetical protein; SPTR: uncharacterized protein YP_004098613.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215: IPR008881: IPR001179: IPR008880; KEGG: ske:Sked_24390 trigger factor; PFAM: trigger factor domain-containing protein; peptidylprolyl isomerase FKBP-type; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor YP_004098614.1 KEGG: der:Dere_GG18701 GG18701 gene product from transcript GG18701-RA; SPTR: uncharacterized protein YP_004098615.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907: IPR018215; KEGG: kse:Ksed_09090 ATP-dependent Clp protease proteolytic subunit ClpP; PFAM: peptidase S14 ClpP; PRIAM: endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease proteolytic subunit ClpP YP_004098616.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907: IPR018215; KEGG: kra:Krad_3516 endopeptidase Clp; PFAM: peptidase S14 ClpP; PRIAM: endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease proteolytic subunit ClpP YP_004098617.1 COGs: COG4281 acyl-CoA-binding protein; InterPro IPR000582; KEGG: ddr:Deide_03020 acyl-CoA-binding protein 1, (ACBP-1), (diazepam-binding inhibitor, DBI); PFAM: acyl-coA-binding protein ACBP; SPTR: acyl-CoA-binding protein; PFAM: acyl CoA binding protein YP_004098618.1 InterPro IPR008265; KEGG: mlu:Mlut_20280 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF559) YP_004098619.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR004487: IPR010603: IPR013093: IPR019489: IPR 003593; KEGG: kra:Krad_3515 ATP-dependent protease ATP-binding subunit ClpX; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; SMART: ATPase AAA; SPTR: ATP-dependent Clp protease ATP-binding subunit clpX; TIGRFAM: ATP-dependent Clp protease ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004098620.1 KEGG: nca:Noca_3532 hypothetical protein; SPTR: uncharacterized protein YP_004098621.1 KEGG: nca:Noca_1480 hypothetical protein; SPTR: uncharacterized protein YP_004098622.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor A (vWA) domain); InterPro IPR002881; KEGG: kfl:Kfla_1428 protein of unknown function DUF58; PFAM: protein of unknown function DUF58; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF58 YP_004098623.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703; KEGG: nca:Noca_1478 ATPase; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: ATPase associated with various cellular activities, AAA_3; PFAM: ATPase family associated with various cellular activities (AAA) YP_004098624.1 KEGG: saq:Sare_0844 hypothetical protein; SPTR: uncharacterized protein YP_004098625.1 KEGG: nca:Noca_1476 hypothetical protein; SPTR: uncharacterized protein YP_004098626.1 COGs: COG0525 Valyl-tRNA synthetase; InterPro IPR019754: IPR001412: IPR002300: IPR013155; KEGG: kse:Ksed_09130 valyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; SPTR: Valyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); anticodon-binding domain YP_004098627.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR004552: IPR002123; KEGG: nfa:nfa1490 1-acylglycerol-3-phosphate O-acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acylglycerol-3-phosphate O-acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004098628.1 COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: sro:Sros_7273 hypothetical protein; PFAM: protein of unknown function DUF2344; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344) YP_004098629.1 COGs: COG1530 ribonuclease G and E; InterPro IPR004659: IPR017937: IPR019307: IPR003029; KEGG: sgr:SGR_4940 hypothetical protein; PFAM: RNA-binding protein AU-1/ribonuclease E/G; SPTR: uncharacterized protein; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family YP_004098630.1 COGs: COG0261 ribosomal protein L21; InterPro IPR001787: IPR018258; KEGG: kse:Ksed_11540 50S ribosomal protein L21P; PFAM: ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: ribosomal protein L21; manually curated; PFAM: ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_004098631.1 COGs: COG0211 ribosomal protein L27; InterPro IPR001684: IPR018261; KEGG: srt:Srot_1753 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_004098632.1 COGs: COG0536 GTPase; InterProIPR014100: IPR015349: IPR006073: IPR006074: IPR 006169: IPR002917; KEGG: kse:Ksed_11560 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; GTP1/OBG domain protein; SPTR: GTP-binding protein; TIGRFAM: GTP-binding protein Obg/CgtA; Obg family GTPase CgtA; PFAM: GTPase of unknown function; Domain of unknown function (DUF1967); GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; Obg family GTPase CgtA, C-terminal extension; small GTP-binding protein domain YP_004098633.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR010559: IPR003594; KEGG: nca:Noca_0358 histidine kinase internal region; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: histidine kinase internal region; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004098634.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: nca:Noca_0357 response regulator receiver; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004098635.1 KEGG: tbi:Tbis_2132 hypothetical protein; SPTR: uncharacterized protein YP_004098636.1 COGs: COG4147 symporter; InterPro IPR001734; KEGG: sro:Sros_6322 SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; SPTR: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family YP_004098637.1 COGs: COG3162 membrane protein; InterPro IPR007436; KEGG: ske:Sked_13330 predicted membrane protein; PFAM: protein of unknown function DUF485; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF485 YP_004098638.1 COGs: COG4147 symporter; InterPro IPR019900: IPR001734; KEGG: bcv:Bcav_3373 SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; SPTR: SSS sodium solute transporter superfamily; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: transporter SSS family YP_004098639.1 COGs: COG4898 conserved hypothetical protein; InterPro IPR014580; KEGG: nca:Noca_4461 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033199; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2200) YP_004098640.1 COGs: COG0263 glutamate 5-kinase; InterProIPR005715: IPR011529: IPR001057: IPR008162: IPR 019797: IPR001048: IPR002478; KEGG: sro:Sros_7268 glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; PRIAM: glutamate 5-kinase; SMART: PUA domain containing protein; SPTR: gamma-glutamyl kinase; TIGRFAM: glutamate 5-kinase; PFAM: PUA domain; Amino acid kinase family; TIGRFAM: glutamate 5-kinase YP_004098641.1 COGs: COG0422 thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: nca:Noca_3400 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC YP_004098642.1 COGs: COG0351 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399: IPR013749; KEGG: nca:Noca_3401 phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase type-1; PRIAM: phosphomethylpyrimidine kinase; SPTR: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_004098643.1 COGs: COG0352 thiamine monophosphate synthase; InterPro IPR003733; KEGG: nca:Noca_3402 thiamine monophosphate synthase; PFAM: thiamine monophosphate synthase; SPTR: thiamine monophosphate synthase; PFAM: thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004098644.1 COGs: COG2022 Uncharacterized protein of thiazole biosynthesis; InterPro IPR008867; KEGG: tfu:Tfu_1042 thiazole synthase; PFAM: thiazole biosynthesis protein; SPTR: Thiazole synthase; PFAM: Thiazole biosynthesis protein ThiG YP_004098645.1 InterPro IPR010035: IPR003749; KEGG: mmi:MMAR_0719 thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; SPTR: thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_004098646.1 COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR012727: IPR006076; KEGG: sro:Sros_2783 glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; SPTR: glycine oxidase ThiO; TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO YP_004098647.1 COGs: COG0352 thiamine monophosphate synthase; InterPro IPR003733; KEGG: sna:Snas_0911 thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004098648.1 COGs: COG0014 gamma-glutamyl phosphate reductase; InterPro IPR000965: IPR012134: IPR020593: IPR015590; KEGG: saq:Sare_0456 gamma-glutamyl phosphate reductase; PFAM: aldehyde dehydrogenase; PRIAM: glutamate-5-semialdehyde dehydrogenase; SPTR: gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase; PFAM: aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase YP_004098649.1 InterPro IPR013216; KEGG: kfl:Kfla_0490 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004098650.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: sco:SCO4658 glucosyltransferase; PFAM: glycosyl transferase family 2; SPTR: glucosyltransferase; PFAM: glycosyl transferase family 2 YP_004098651.1 KEGG: mlu:Mlut_10160 hypothetical protein; SPTR: uncharacterized protein YP_004098652.1 COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004821: IPR005248: IPR004820; KEGG: kse:Ksed_11580 nicotinate-nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Probable nicotinate-nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain YP_004098653.1 COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: nca:Noca_1821 iojap-like protein; PFAM: Iojap-related protein; SPTR: uncharacterized protein; TIGRFAM: iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein YP_004098654.1 COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: kra:Krad_3448 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase; manually curated; PFAM: phosphoglycerate mutase family YP_004098655.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: nml:Namu_4653 hypothetical protein; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004098656.1 COGs: COG0183 acetyl-CoA acetyltransferase; InterPro IPR002155: IPR020616: IPR020617; KEGG: pfr:PFREUD_02820 acetyl-CoA C-acetyltransferase; PFAM: thiolase-like; PRIAM: acetyl-CoA C-acetyltransferase; SPTR: acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase, C-terminal domain; thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_004098657.1 COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: gob:Gobs_1528 ABC transporter related protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type cobalt transporter ATPase component; PFAM: ABC transporter YP_004098658.1 COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339; KEGG: nml:Namu_4656 cobalt transporter; PFAM: cobalt transporter; SPTR: uncharacterized protein; PFAM: Cobalt transporter YP_004098659.1 COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: gob:Gobs_1529 BioY protein; PFAM: BioY protein; SPTR: Uncharacterized conserved protein-like protein; PFAM: BioY family YP_004098660.1 InterPro IPR011600; KEGG: npu:Npun_R3338 peptidase C14, caspase catalytic subunit P20; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: uncharacterized protein; PFAM: Caspase domain YP_004098661.1 KEGG: gob:Gobs_2142 40-residue YVTN family beta-propeller repeat protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1083) YP_004098662.1 InterPro IPR020137; KEGG: stp:Strop_1903 hypothetical protein; SPTR: uncharacterized protein YP_004098663.1 COGs: COG5496 thioesterase; KEGG: cai:Caci_7731 thioesterase superfamily protein; SPTR: thioesterase YP_004098664.1 COGs: COG0495 leucyl-tRNA synthetase; InterProIPR002302: IPR001412: IPR015413: IPR002300: IPR 013155; KEGG: bcv:Bcav_1730 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; tRNA synthetase class I (M); aminoacyl-tRNA synthetase class Ia; SPTR: leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); tRNA synthetases class I (M); anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family YP_004098665.1 COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: sco:SCO2569 hypothetical protein; PFAM: DegV family protein; SPTR: uncharacterized protein; TIGRFAM: degV family protein; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family YP_004098666.1 COGs: COG0344 membrane protein; InterPro IPR020788: IPR003811; KEGG: gme:Gmet_3020 membrane protein; PFAM: protein of unknown function DUF205; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase YP_004098667.1 COGs: COG0788 Formyltetrahydrofolate hydrolase; InterPro IPR004810: IPR002912: IPR002376; KEGG: scb:SCAB_51501 formyltetrahydrofolate deformylase; PFAM: formyl transferase; amino acid-binding ACT domain protein; SPTR: Formyltetrahydrofolate deformylase; TIGRFAM: formyltetrahydrofolate deformylase; PFAM: ACT domain; Formyl transferase; TIGRFAM: formyltetrahydrofolate deformylase YP_004098668.1 COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR004509: IPR019554; KEGG: kse:Ksed_17330 DNA uptake protein; PFAM: Soluble ligand binding domain; SPTR: DNA-binding protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein YP_004098669.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2 YP_004098670.1 COGs: COG0405 gamma-glutamyltransferase; InterPro IPR000101; KEGG: kfl:Kfla_5445 gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; PRIAM: gamma-glutamyltransferase; SPTR: gamma-glutamyltranspeptidase; PFAM: gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase YP_004098671.1 COGs: COG2128 conserved hypothetical protein; InterPro IPR010195: IPR004675: IPR003779; KEGG: dge:Dgeo_1446 hypothetical protein; PFAM: carboxymuconolactone decarboxylase; SPTR: Uncharacterised peroxidase-related; TIGRFAM: peroxidase; alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase family; TIGRFAM: peroxidase; alkylhydroperoxidase AhpD family core domain YP_004098672.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: kse:Ksed_17270 transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004098673.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: silent information regulator protein Sir2; SPTR: SIR2-like regulatory protein; PFAM: Sir2 family YP_004098674.1 InterPro IPR006311; KEGG: kse:Ksed_18040 hypothetical protein; SPTR: uncharacterized protein YP_004098675.1 COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: gbr:Gbro_4732 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004098676.1 InterPro IPR002514; KEGG: rop:ROP_pROB01-03840 transposase; PFAM: transposase IS3/IS911 family protein; SPTR: transposase YP_004098677.1 KEGG: msm:MSMEG_1644 hypothetical protein; SPTR: uncharacterized protein YP_004098678.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR006200: IPR006197: IPR006199: IPR019759; KEGG: cfl:Cfla_1566 transcriptional repressor, LexA family; PFAM: LexA DNA-binding domain protein; peptidase S24/S26A/S26B, conserved region; SPTR: LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA binding domain; peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_004098679.1 InterPro IPR018392; KEGG: kse:Ksed_17220 LysM domain-containing protein; PFAM: peptidoglycan-binding lysin domain; SPTR: uncharacterized protein; PFAM: LysM domain YP_004098680.1 KEGG: bcv:Bcav_3285 hypothetical protein; SPTR: uncharacterized protein YP_004098681.1 InterPro IPR010427; KEGG: bcv:Bcav_3284 protein of unknown function DUF1023; PFAM: protein of unknown function DUF1023; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase of unknown function (DUF1023) YP_004098682.1 KEGG: sen:SACE_5911 hypothetical protein; SPTR: hypothetical protein YP_004098683.1 COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; InterPro IPR003796: IPR005144; KEGG: aau:AAur_1725 transcriptional regulator NrdR; PFAM: ATP-cone domain protein; SPTR: transcriptional repressor nrdR; PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR YP_004098684.1 InterPro IPR013344: IPR000788: IPR013678; KEGG: kse:Ksed_17170 vitamin B12-dependent ribonucleotide reductase; PFAM: ribonucleotide reductase class II vitamin B12-dependent; ribonucleotide reductase large subunit; PRIAM: ribonucleoside-diphosphate reductase; SPTR: ribonucleotide-diphosphate reductase subunit alpha; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: class II vitamin B12-dependent ribonucleotide reductase; ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent YP_004098685.1 KEGG: mab:MAB_0397c hypothetical protein; SPTR: uncharacterized protein YP_004098686.1 InterPro IPR001387; KEGG: kfl:Kfla_0788 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004098687.1 COGs: COG3550 conserved hypothetical protein; InterPro IPR017508: IPR012894: IPR012893; KEGG: kfl:Kfla_0789 HipA N-terminal domain protein; PFAM: HipA domain protein; SPTR: HipA N-terminal domain protein; TIGRFAM: HipA N-terminal domain protein; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain; TIGRFAM: HipA N-terminal domain YP_004098688.1 COGs: COG2421 acetamidase/formamidase; InterPro IPR004304; KEGG: gob:Gobs_1964 acetamidase/formamidase; PFAM: acetamidase/Formamidase; SPTR: acetamidase/Formamidase; PFAM: acetamidase/Formamidase family YP_004098689.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR020904: IPR002198; KEGG: msm:MSMEG_4382 dehydrogenase/reductase SDR family protein member 10; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: dehydrogenase/reductase SDR family protein member 10; PFAM: short chain dehydrogenase YP_004098690.1 COGs: COG4291 membrane protein; InterPro IPR009781; KEGG: rer:RER_34620 hypothetical protein; PFAM: protein of unknown function DUF1345; SPTR: Conserved hypothetical membrane protein; PFAM: protein of unknown function (DUF1345) YP_004098691.1 InterPro IPR013493; KEGG: sma:SAV_7222 hypothetical protein; PFAM: Conserved hypothetical protein CHP02677; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2397); TIGRFAM: conserved hypothetical protein TIGR02677 YP_004098692.1 InterPro IPR013494; KEGG: sma:SAV_7223 hypothetical protein; PFAM: Conserved hypothetical protein CHP02678; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2398); TIGRFAM: conserved hypothetical protein TIGR02678 YP_004098693.1 COGs: COG1196 chromosome segregation ATPase; InterPro IPR013496; KEGG: sma:SAV_7224 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR02680 YP_004098694.1 KEGG: sma:SAV_7225 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function N-terminus (DUF3323); protein of unknown function C-terminus (DUF2399); TIGRFAM: conserved hypothetical protein TIGR02679 YP_004098695.1 KEGG: kfl:Kfla_4292 hypothetical protein; SPTR: uncharacterized protein YP_004098696.1 KEGG: azl:AZL_013690 SecG protein; SPTR: SecG protein YP_004098697.1 KEGG: sro:Sros_5498 hypothetical protein; SPTR: uncharacterized protein; PFAM: Rho termination factor, N-terminal domain; ChaB YP_004098698.1 InterPro IPR002711: IPR003615; KEGG: kse:Ksed_09510 HNH endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; PFAM: HNH endonuclease; Domain of unknown function DUF222 YP_004098699.1 COGs: COG0657 esterase/lipase; KEGG: nfa:nfa23150 hypothetical protein; SPTR: Hydrolase; PFAM: alpha/beta hydrolase fold YP_004098700.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: cmi:CMM_0858 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family YP_004098701.1 KEGG: sus:acid_3612 hypothetical protein; SPTR: uncharacterized protein YP_004098702.1 KEGG: nca:Noca_4891 gualylate cyclase protein; SPTR: gualylate cyclase protein YP_004098703.1 COGs: COG3899 ATPase; InterPro IPR000792: IPR019734; KEGG: sti:Sthe_2247 LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; hypothetical protein; SPTR: LuxR family transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family YP_004098704.1 KEGG: bcv:Bcav_0070 hypothetical protein; SPTR: uncharacterized protein YP_004098705.1 COGs: COG2072 flavoprotein involved in K+ transport; InterPro IPR013027: IPR001327; KEGG: rha:RHA1_ro04494 potassium uptake protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Possible potassium uptake protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004098706.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: mjl:Mjls_0414 LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family YP_004098707.1 InterPro IPR018357: IPR001451; KEGG: cfl:Cfla_0787 transferase; SPTR: transferase YP_004098708.1 COGs: COG1295 membrane protein; InterPro IPR017039: IPR004664; KEGG: rop:ROP_32170 ribonuclease; PFAM: ribonuclease BN; SPTR: ribonuclease; TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_004098709.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: ske:Sked_15540 predicted oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: aldo/keto reductase; SPTR: K+ channel subunit beta; PFAM: Aldo/keto reductase family YP_004098710.1 InterPro IPR006015: IPR006016; KEGG: sna:Snas_3659 UspA domain-containing protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family YP_004098711.1 InterPro IPR011528; KEGG: mgi:Mflv_5176 hypothetical protein; PFAM: NERD domain protein; SPTR: uncharacterized protein; PFAM: Nuclease-related domain; Uncharacterized conserved protein (DUF2075) YP_004098712.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015: IPR006016; KEGG: saq:Sare_1891 UspA domain-containing protein; PFAM: UspA domain-containing protein; SPTR: Usp family protein; PFAM: Universal stress protein family YP_004098713.1 KEGG: pfr:PFREUD_17160 hypothetical protein; SPTR: uncharacterized protein; PFAM: activator of Hsp90 ATPase homolog 1-like protein YP_004098714.1 COGs: COG2183 transcriptional accessory protein; InterPro IPR018974: IPR003029: IPR006641; KEGG: amd:AMED_1551 transcriptional accessory protein; PFAM: Tex-like protein-like; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: RNA binding S1 domain protein; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region YP_004098715.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120; KEGG: rsa:RSal33209_2315 amidase; PFAM: amidase; SPTR: amidase; PFAM: amidase YP_004098716.1 COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: kfl:Kfla_4659 extracellular solute-binding protein family 5; PFAM: extracellular solute-binding protein family 5; SPTR: extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004098717.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: kfl:Kfla_4658 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004098718.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: kfl:Kfla_4657 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004098719.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR010066: IPR017871: IPR003439: IPR013563: IPR 003593; KEGG: kfl:Kfla_4656 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004098720.1 COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterPro IPR017871: IPR003439: IPR013563: IPR003593; KEGG: kfl:Kfla_4655 ABC transporter protein; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region YP_004098721.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: kfl:Kfla_4654 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family YP_004098722.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904; KEGG: amd:AMED_0073 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004098723.1 COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: msv:Mesil_1795 guanine deaminase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; TIGRFAM: guanine deaminase YP_004098724.1 COGs: COG1975 xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR014308: IPR003777; KEGG: sco:SCO4973 hypothetical protein; PFAM: protein of unknown function DUF182; SPTR: uncharacterized protein; TIGRFAM: xanthine dehydrogenase accessory protein XdhC; PFAM: XdhC and CoxI family; TIGRFAM: xanthine dehydrogenase accessory protein XdhC YP_004098725.1 COGs: COG4631 xanthine dehydrogenase molybdopterin-binding subunit B; InterPro IPR014309: IPR000674: IPR008274; KEGG: nca:Noca_1637 xanthine oxidase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; PRIAM: xanthine oxidase; SPTR: xanthine oxidase; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit YP_004098726.1 COGs: COG4630 xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A; InterProIPR006058: IPR001041: IPR002888: IPR002346: IPR 005107: IPR016166; KEGG: nca:Noca_1636 molybdopterin dehydrogenase, FAD-binding; PFAM: molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain-containing protein; ferredoxin; CO dehydrogenase flavoprotein domain protein; SPTR: dehydrogenase; PFAM: 2Fe-2S iron-sulfur cluster binding domain; FAD binding domain in molybdopterin dehydrogenase; [2Fe-2S] binding domain; CO dehydrogenase flavoprotein C-terminal domain; TIGRFAM: xanthine dehydrogenase, small subunit YP_004098727.1 KEGG: kfl:Kfla_4292 hypothetical protein; SPTR: uncharacterized protein YP_004098728.1 KEGG: dwi:Dwil_GK12364 GK12364 gene product from transcript GK12364-RA; SPTR: GK12364 YP_004098729.1 COGs: COG1401 GTPase subunit of restriction endonuclease; InterPro IPR011704: IPR003593; KEGG: bfa:Bfae_05450 GTPase subunit of restriction endonuclease; PFAM: ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; SPTR: ATPase family associated with various cellular activities (AAA), ; PFAM: AAA domain (dynein-related subfamily) YP_004098730.1 COGs: COG4268 McrBC 5-methylcytosine restriction system component; InterPro IPR019292; KEGG: cai:Caci_6960 hypothetical protein; PFAM: 5-methylcytosine restriction system component-like protein; SPTR: uncharacterized protein; PFAM: McrBC 5-methylcytosine restriction system component YP_004098731.1 InterPro IPR011637; KEGG: bcv:Bcav_3582 DoxX family protein; PFAM: DoxX family protein; SPTR: DoxX family protein; PFAM: DoxX YP_004098732.1 COGs: COG2251 nuclease (RecB family); InterPro IPR019993; KEGG: gob:Gobs_3698 RecB family nuclease, SPTR: RecB family nuclease, ; TIGRFAM: RecB family nuclease, TIGRFAM: RecB family nuclease, , TM0106 family YP_004098733.1 COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502: IPR000387; KEGG: ske:Sked_03580 ADP-ribosylglycohydrolase; PFAM: ADP-ribosylation/crystallin J1; SPTR: ribosylglycohydrolase; PFAM: ADP-ribosylglycohydrolase YP_004098734.1 KEGG: tbi:Tbis_2449 hypothetical protein; SPTR: uncharacterized protein YP_004098735.1 KEGG: kfl:Kfla_6683 hypothetical protein; SPTR: integral membrane protein YP_004098736.1 COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: kfl:Kfla_7010 methicillin resistance protein; PFAM: methicillin resistance protein; SPTR: uncharacterized protein; PFAM: FemAB family YP_004098737.1 KEGG: rop:ROP_08780 dihydrolipoamide acetyltransferase; SPTR: dihydrolipoamide acyltransferase YP_004098738.1 COGs: COG1643 HrpA-like helicase; InterProIPR010222: IPR001650: IPR007502: IPR011709: IPR 014001: IPR003593: IPR014021; KEGG: stp:Strop_1712 ATP-dependent helicase HrpA; PFAM: protein of unknown function DUF1605; helicase-associated domain protein; helicase; SMART: DEAD-like helicase; ATPase AAA; helicase; SPTR: ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; manually curated; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF3418); Domain of unknown function (DUF1605); DEAD/DEAH box helicase; TIGRFAM: ATP-dependent helicase HrpA YP_004098739.1 InterPro IPR008492; KEGG: amd:AMED_7844 hypothetical protein; SPTR: uncharacterized protein; PFAM: PAC2 family YP_004098740.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterPro IPR002298: IPR001098; KEGG: fal:FRAAL3779 DNA polymerase I; PFAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase; SPTR: DNA polymerase I; PFAM: DNA polymerase family A YP_004098741.1 COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: mmi:MMAR_3453 aminotransferase; PFAM: aminotransferase class I and II; SPTR: transferase; PFAM: Aminotransferase class I and II YP_004098742.1 KEGG: kse:Ksed_16720 hypothetical protein; SPTR: uncharacterized protein YP_004098743.1 InterPro IPR010652; KEGG: tfu:Tfu_2752 hypothetical protein; PFAM: protein of unknown function DUF1232; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1232) YP_004098744.1 KEGG: cfl:Cfla_2059 hypothetical protein; SPTR: uncharacterized protein YP_004098745.1 COGs: COG2021 homoserine acetyltransferase; InterPro IPR006296: IPR008220: IPR000073; KEGG: amd:AMED_7928 homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; PRIAM: homoserine O-acetyltransferase; SPTR: homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase YP_004098746.1 InterPro IPR006015: IPR006016; KEGG: kfl:Kfla_3427 UspA domain protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family YP_004098747.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR012760: IPR000943: IPR005479: IPR 009042: IPR007627: IPR007624: IPR007630; KEGG: kse:Ksed_16690 RNA polymerase sigma factor RpoD, C-terminal domain/RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain YP_004098748.1 COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: nca:Noca_4205 adenylylsulfate kinase; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: Ptp; PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_004098749.1 COGs: COG1305 transglutaminase-like protein; InterPro IPR002931; KEGG: sgr:SGR_5409 hypothetical protein; PFAM: transglutaminase; SMART: transglutaminase; SPTR: membrane protein; PFAM: transglutaminase-like superfamily YP_004098750.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor A (vWA) domain); InterPro IPR002881; KEGG: ace:Acel_0999 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: membrane protein; PFAM: protein of unknown function DUF58 YP_004098751.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703: IPR003593; KEGG: cai:Caci_1651 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: ATPase AAA; SPTR: regulatory protein; PFAM: ATPase family associated with various cellular activities (AAA) YP_004098752.1 COGs: COG2001 conserved hypothetical protein; InterPro IPR003444: IPR020603; KEGG: kse:Ksed_16650 MraZ protein; PFAM: MraZ domain; SPTR: protein mraZ; TIGRFAM: MraZ protein; PFAM: MraZ protein; TIGRFAM: mraZ protein YP_004098753.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: kse:Ksed_16640 S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; SPTR: ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW YP_004098754.1 KEGG: cai:Caci_1654 hypothetical protein; SPTR: uncharacterized protein YP_004098755.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR005761: IPR000713: IPR013221: IPR004101; KEGG: kra:Krad_3204 UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase YP_004098756.1 COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR005863: IPR000713: IPR013221: IPR004101; KEGG: scb:SCAB_67971 UDP-N-acetylmuramoyl-tripeptide--D-alan yl-D-alanineligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-d iaminopimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_004098757.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR003524: IPR018480: IPR018481; KEGG: ske:Sked_22830 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: glycosyl transferase, family 4, conserved region; phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR:phospho-N-acetylmuramoyl-pentapeptide-transfer ase; TIGRFAM:phospho-N-acetylmuramoyl-pentapeptide-trans ferase; PFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; glycosyl transferase family 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase YP_004098758.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR005762: IPR018109: IPR013221: IPR004101; KEGG: nca:Noca_3065 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: FAD binding domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004098759.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437: IPR018365: IPR001182; KEGG: kra:Krad_3200 cell division protein FtsW; PFAM: cell cycle protein; SPTR: cell division protein FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; TIGRFAM: cell division protein FtsW YP_004098760.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR006009: IPR004276: IPR007235; KEGG: kse:Ksed_16570 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: glycosyltransferase 28 domain; glycosyl transferase family 28; SPTR: N-acetylglucosaminyl transferase; TIGRFAM:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: glycosyltransferase family 28 N-terminal domain; glycosyltransferase family 28 C-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_004098761.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR005758: IPR000713: IPR013221: IPR004101; KEGG: gob:Gobs_3262 UDP-N-acetylmuramate/alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate/alanine ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase YP_004098762.1 COGs: COG1589 cell division septal protein; InterPro IPR013685; KEGG: kfl:Kfla_2888 polypeptide-transport-associated domain protein FtsQ-type; PFAM: polypeptide-transport-associated domain protein FtsQ-type; SPTR: cell division protein FtsQ; PFAM: POTRA domain, FtsQ-type YP_004098763.1 COGs: COG0206 cell division GTPase; InterPro IPR000158: IPR020805: IPR003008: IPR018316; KEGG: kra:Krad_3196 cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: cell division protein ftsZ; TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004098764.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: kra:Krad_3195 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family YP_004098765.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR011078: IPR001608; KEGG: tcu:Tcur_2922 alanine racemase domain protein; PFAM: alanine racemase domain protein; SPTR: uncharacterized protein; PFAM: alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_004098766.1 COGs: COG1799 conserved hypothetical protein; InterPro IPR007561; KEGG: cfl:Cfla_1600 protein of unknown function DUF552; PFAM: protein of unknown function DUF552; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF552) YP_004098767.1 InterPro IPR003425; KEGG: cfl:Cfla_1601 protein of unknown function YGGT; PFAM: protein of unknown function YGGT; SPTR: uncharacterized protein; PFAM: YGGT family YP_004098768.1 InterPro IPR019933: IPR007793; KEGG: cdi:DIP1590 antigen 84; PFAM: DivIVA family protein; SPTR: Wag31; TIGRFAM: DivIVA domain; TIGRFAM: DivIVA domain YP_004098769.1 COGs: COG1734 DnaK suppressor protein; InterPro IPR020458: IPR000962; KEGG: sma:SAV_6131 DNA-binding protein; SPTR: DNA-binding protein; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA YP_004098770.1 COGs: COG0597 Lipoprotein signal peptidase; InterPro IPR001872; KEGG: xce:Xcel_1293 lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: lipoprotein signal peptidase; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_004098771.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225: IPR002942: IPR006145; KEGG: cai:Caci_5735 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: ribosomal large subunit pseudouridine synthase; TIGRFAM: pseudouridine synthase; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase YP_004098772.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805: IPR004013: IPR011708: IPR004365: IPR 003141; KEGG: kse:Ksed_16450 DNA polymerase III subunit alpha; PFAM: DNA polymerase III subunit alpha; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III subunit alpha; TIGRFAM: DNA polymerase III, subunit alpha; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004098773.1 KEGG: sti:Sthe_2375 hypothetical protein; SPTR: uncharacterized protein YP_004098774.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006224: IPR006145; KEGG: sen:SACE_3351 ribosomal pseudouridine synthase; PFAM: pseudouridine synthase; SPTR: RNA pseudouridylate synthase; PFAM: RNA pseudouridylate synthase YP_004098775.1 COGs: COG2374 extracellular nuclease; InterPro IPR005135; KEGG: azo:azo1484 extracellular nuclease; PFAM: endonuclease/exonuclease/phosphatase; SPTR: extracellular nuclease; PFAM: endonuclease/exonuclease/phosphatase family YP_004098776.1 COGs: COG3265 gluconate kinase; InterPro IPR006001: IPR000623; KEGG: art:Arth_0505 gluconate kinase; PFAM: shikimate kinase; PRIAM: gluconokinase; SPTR: gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family YP_004098777.1 COGs: COG1770 Protease II; InterPro IPR002470: IPR004106; KEGG: kfl:Kfla_3414 oligopeptidase B; PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; PRIAM: oligopeptidase B; SPTR: Protease II; PFAM: prolyl oligopeptidase, N-terminal beta-propeller domain; prolyl oligopeptidase family YP_004098778.1 COGs: COG0141 Histidinol dehydrogenase; InterPro IPR012131: IPR001692; KEGG: tfu:Tfu_1150 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase YP_004098779.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR001917: IPR004839; KEGG: sna:Snas_3996 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_004098780.1 COGs: COG0131 imidazoleglycerol-phosphate dehydratase; InterPro IPR000807: IPR020565; KEGG: bcv:Bcav_2392 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: imidazoleglycerol-phosphate dehydratase; SPTR: imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase YP_004098781.1 COGs: COG0118 glutamine amidotransferase; InterPro IPR010139: IPR016226: IPR000991: IPR017926; KEGG: cai:Caci_5726 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; SPTR: Imidazole glycerol phosphate synthase subunit HisH; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_004098782.1 COGs: COG0106 phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR010188: IPR006062; KEGG: nda:Ndas_3187 bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein; PRIAM: phosphoribosylanthranilate isomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein; TIGRFAM: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase/N-(5'phosphoribosyl)anthranilate isomerase; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_004098783.1 KEGG: aau:AAur_1609 hypothetical protein; SPTR: uncharacterized protein YP_004098784.1 COGs: COG2733 membrane protein; InterPro IPR007383; KEGG: nca:Noca_1692 hypothetical protein; PFAM: protein of unknown function DUF445; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF445) YP_004098785.1 COGs: COG0480 translation elongation factors (GTPase); InterProIPR005225: IPR000795: IPR004161: IPR005517: IPR 000640; KEGG: nca:Noca_4599 elongation factor G; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: translation elongation factor EF-G; TIGRFAM: small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004098786.1 InterPro IPR011701; KEGG: rsa:RSal33209_0741 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Conserved membrane protein, permease; PFAM: Major Facilitator Superfamily YP_004098787.1 COGs: COG0290 translation initiation factor 3 (IF-3); InterPro IPR001288: IPR019814: IPR019815; KEGG: kra:Krad_3169 translation initiation factor IF-3; PFAM: translation initiation factor 3-like; SPTR: translation initiation factor IF-3; TIGRFAM: translation initiation factor IF-3; manually curated; PFAM: translation initiation factor IF-3, C-terminal domain; translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_004098788.1 InterPro IPR001706: IPR018265: IPR021137; KEGG: cfl:Cfla_1625 ribosomal protein L35; PFAM: ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_004098789.1 COGs: COG0292 ribosomal protein L20; InterPro IPR005813; KEGG: cfl:Cfla_1626 ribosomal protein L20; PFAM: ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: ribosomal protein L20; PFAM: ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_004098790.1 COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537; KEGG: xce:Xcel_1319 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: rRNA methyltransferase; PFAM: SpoU rRNA methylase family; RNA 2'-O ribose methyltransferase substrate binding YP_004098791.1 COGs: COG2205 osmosensitive K+ channel histidine kinase; InterProIPR000014: IPR003661: IPR003594: IPR005467: IPR 004358: IPR013656; KEGG: sco:SCO1596 two-component sensor; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Two-component sensor; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004098792.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR006195: IPR004188: IPR002319: IPR004529; KEGG: tcu:Tcur_2145 phenylalanyl-tRNA synthetase, subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: Phenylalanyl-tRNA synthetase subunit alpha; TIGRFAM: phenylalanyl-tRNA synthetase, subunit alpha; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, subunit alpha YP_004098793.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: kra:Krad_3163 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase subunit beta, non-spirochete bacterial YP_004098794.1 COGs: COG0002 acetylglutamate semialdehyde dehydrogenase; InterPro IPR000706: IPR000534: IPR012280; KEGG: kra:Krad_3161 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: semialdehyde dehydrogenase, dimerisation domain; semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form YP_004098795.1 COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); InterPro IPR002813; KEGG: rsa:RSal33209_0778 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; PFAM: arginine biosynthesis protein ArgJ; PRIAM: glutamate N-acetyltransferase; SPTR: Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; TIGRFAM: arginine biosynthesis bifunctional protein ArgJ; PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase YP_004098796.1 COGs: COG0548 acetylglutamate kinase; InterPro IPR001057: IPR011148: IPR001048: IPR004662; KEGG: cfl:Cfla_1643 acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: acetylglutamate kinase; TIGRFAM: acetylglutamate kinase; PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase YP_004098797.1 COGs: COG4992 ornithine/acetylornithine aminotransferase; InterPro IPR005814: IPR004636; KEGG: art:Arth_1499 acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases YP_004098798.1 COGs: COG1438 Arginine repressor; InterPro IPR001669: IPR020899; KEGG: aau:AAur_1636 arginine repressor; PFAM: Arginine repressor-like; SPTR: Arginine repressor; TIGRFAM: arginine repressor; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_004098799.1 COGs: COG0165 Argininosuccinate lyase; InterPro IPR003031: IPR000362: IPR020557: IPR009049; KEGG: ske:Sked_22260 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase YP_004098800.1 COGs: COG2094 3-methyladenine DNA glycosylase; InterPro IPR003180; KEGG: ace:Acel_1255 3-methyladenine DNA glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); SPTR: 3-methyladenine DNA glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); TIGRFAM: DNA-3-methyladenine glycosylase (3mg) YP_004098801.1 COGs: COG0162 Tyrosyl-tRNA synthetase; InterPro IPR002942: IPR002307: IPR002305; KEGG: nml:Namu_4122 tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; RNA-binding S4 domain protein; PRIAM: Tyrosine--tRNA ligase; SMART: RNA-binding S4 domain protein; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: S4 domain; tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_004098802.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: mlu:Mlut_14300 transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: transposase; PFAM: transposase YP_004098803.1 KEGG: sen:SACE_5253 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004098804.1 COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR005834: IPR006357; KEGG: sro:Sros_6062 sugar phosphatase of the HAD superfamily-like protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Sugar phosphatase of the HAD superfamily-like protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily class (subfamily) IIA YP_004098805.1 KEGG: mgi:Mflv_0916 hypothetical protein; SPTR: uncharacterized protein YP_004098806.1 COGs: COG1189 rRNA methylase; InterPro IPR002942: IPR002877: IPR004538; KEGG: mlu:Mlut_14230 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein YP_004098807.1 COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: nca:Noca_2481 inorganic polyphosphate/ATP-NAD kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: inorganic polyphosphate/ATP-NAD kinase; PFAM: ATP-NAD kinase YP_004098808.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003395: IPR004604; KEGG: sma:SAV_6499 DNA recombination and repair protein; PFAM: SMC domain protein; SPTR: DNA repair protein; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_004098809.1 COGs: COG4825 Uncharacterized membrane-anchored protein; InterPro IPR007371; KEGG: cfl:Cfla_1660 thiamin pyrophosphokinase catalytic region; PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; SPTR: uncharacterized protein; PFAM: thiamine pyrophosphokinase C terminal YP_004098810.1 KEGG: kra:Krad_3145 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3186) YP_004098811.1 KEGG: kfl:Kfla_5416 hypothetical protein; SPTR: uncharacterized protein YP_004098812.1 COGs: COG0728 membrane protein virulence factor; InterPro IPR004268; KEGG: gob:Gobs_3004 virulence factor MviN family protein; PFAM: virulence factor MVIN family protein; SPTR: Uncharacterized membrane protein virulence factor-like protein; PFAM: MviN-like protein YP_004098813.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: gob:Gobs_3003 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase; PFAM: glycosyl transferases group 1 YP_004098814.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR017926: IPR004468: IPR017456: IPR000991; KEGG: cfl:Cfla_1664 CTP synthase; PFAM: CTP synthase-like; glutamine amidotransferase class-I; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; manually curated; PFAM: glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase YP_004098815.1 InterPro IPR000086; KEGG: jde:Jden_1133 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004098816.1 COGs: COG3012 conserved hypothetical protein; KEGG: mva:Mvan_2354 SecC motif-containing protein; SPTR: SEC-C motif domain protein YP_004098817.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: art:Arth_3190 acyltransferase 3; PFAM: acyltransferase 3; SPTR: acyltransferase 3; PFAM: acyltransferase family YP_004098818.1 COGs: COG0173 aspartyl-tRNA synthetase; InterProIPR006195: IPR002312: IPR004365: IPR004364: IPR 004115: IPR004524; KEGG: kse:Ksed_12420 aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; GAD domain protein; SPTR: aspartyl-tRNA synthetase; TIGRFAM: aspartyl-tRNA synthetase; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type YP_004098819.1 InterPro IPR000182; KEGG: kse:Ksed_12430 acetyltransferase (GNAT) family protein; SPTR: uncharacterized protein; PFAM: FR47-like protein YP_004098820.1 COGs: COG2409 drug exporter of the RND superfamily; InterPro IPR000731; KEGG: nml:Namu_5174 drug exporter of the RND superfamily-like protein; SPTR: Drug exporter of the RND superfamily-like protein; PFAM: MMPL family YP_004098821.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593: IPR003959; KEGG: kra:Krad_3035 recombination factor protein RarA; PFAM: ATPase AAA central domain protein; SMART: ATPase AAA; SPTR: Conserved ATP/GTP binding protein; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA) YP_004098822.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: kfl:Kfla_2695 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004098823.1 COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: kse:Ksed_12470 ABC-type dipeptide transporter periplasmic component; PFAM: extracellular solute-binding protein family 5; SPTR: ABC-type dipeptide transporter periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004098824.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515: IPR018117; KEGG: kfl:Kfla_2697 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004098825.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR003593: IPR003439: IPR017871: IPR013563: IPR 010066; KEGG: kse:Ksed_12490 oligopeptide/dipeptide ABC transporter ATP-binding protein; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004098826.1 COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterProIPR003593: IPR003439: IPR017871: IPR013563: IPR 010066; KEGG: kse:Ksed_12500 oligopeptide/dipeptide ABC transporter ATP-binding protein; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004098827.1 COGs: COG0013 Alanyl-tRNA synthetase; InterProIPR018165: IPR018164: IPR012947: IPR003156: IPR 002318; KEGG: nca:Noca_2407 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc-like; threonyl/alanyl tRNA synthetase SAD; phosphoesterase DHHA1; SPTR: Alanyl-tRNA synthetase; TIGRFAM: alanyl-tRNA synthetase; PFAM: DHHA1 domain; threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase YP_004098828.1 COGs: COG0816 endonuclease involved in recombination ( Holliday junction resolvase in Mycoplasmas and B. subtilis); InterPro IPR006641: IPR005227; KEGG: tbi:Tbis_2046 Holliday junction resolvase YqgF; PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; SPTR: Holliday junction resolvase YqgF; PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: RNAse H-fold protein YqgF YP_004098829.1 COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: kra:Krad_3030 aminodeoxychorismate lyase; PFAM: aminodeoxychorismate lyase; SPTR: Aminodeoxychorismate lyase; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family YP_004098830.1 COGs: COG0169 shikimate 5-dehydrogenase; InterPro IPR013708; KEGG: gob:Gobs_3155 shikimate-5-dehydrogenase; PFAM: shikimate dehydrogenase substrate binding domain protein; SPTR: shikimate-5-dehydrogenase; PFAM: shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate-5-dehydrogenase, fungal AROM-type; shikimate 5-dehydrogenase YP_004098831.1 InterPro IPR000045; KEGG: kra:Krad_3020 peptidase A24A domain protein; PFAM: peptidase A24A prepilin type IV; SPTR: uncharacterized protein; PFAM: type IV leader peptidase family YP_004098832.1 COGs: COG0082 chorismate synthase; InterPro IPR020541: IPR000453; KEGG: xce:Xcel_1694 chorismate synthase; PFAM: chorismate synthase; PRIAM: chorismate synthase; SPTR: chorismate synthase; TIGRFAM: chorismate synthase; PFAM: chorismate synthase; TIGRFAM: chorismate synthase YP_004098833.1 COGs: COG0703 shikimate kinase; InterPro IPR000623; KEGG: bcv:Bcav_2020 shikimate kinase; PFAM: shikimate kinase; PRIAM: shikimate kinase; SPTR: shikimate kinase; PFAM: shikimate kinase YP_004098834.1 COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR016303: IPR016037: IPR002658; KEGG: kra:Krad_3013 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase YP_004098835.1 COGs: COG0757 3-dehydroquinate dehydratase II; InterPro IPR018509: IPR001874; KEGG: ace:Acel_1306 3-dehydroquinate dehydratase; PFAM: dehydroquinase class II; PRIAM: 3-dehydroquinate dehydratase; SPTR: 3-dehydroquinate dehydratase; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II YP_004098836.1 COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR000408; KEGG: kra:Krad_0164 ATP-dependent DNA helicase; SPTR: ATP-dependent DNA helicase YP_004098837.1 COGs: COG0231 translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); InterProIPR013852: IPR020599: IPR011768: IPR013185: IPR 001059: IPR015365; KEGG: cfl:Cfla_1838 translation elongation factor P; PFAM: Elongation factor KOW-like domain-containing protein; Elongation factor P/YeiP protein; Elongation factor P; SPTR: Elongation factor P; TIGRFAM: translation elongation factor P; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P YP_004098838.1 COGs: COG0781 transcription termination factor; InterPro IPR006027: IPR011605; KEGG: kse:Ksed_12640 NusB antitermination factor; PFAM: NusB/RsmB/TIM44; SPTR: NusB antitermination factor; TIGRFAM: transcription antitermination factor NusB; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_004098839.1 KEGG: mkm:Mkms_2155 hypothetical protein; SPTR: uncharacterized protein; PFAM: NADPH-dependent FMN reductase YP_004098840.1 COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: kra:Krad_3006 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: uracil phosphoribosyltransferase; SPTR: Pyrimidine regulatory protein PyrR; PFAM: phosphoribosyl transferase domain YP_004098841.1 COGs: COG0540 aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: kse:Ksed_12660 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_004098842.1 COGs: COG0044 dihydroorotase and related cyclic amidohydrolase; InterPro IPR002195: IPR006680: IPR004722; KEGG: kse:Ksed_12670 dihydroorotase; PFAM: amidohydrolase; SPTR: dihydroorotase; TIGRFAM: dihydroorotase; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase YP_004098843.1 COGs: COG0505 carbamoylphosphate synthase small subunit; InterProIPR017926: IPR001317: IPR011702: IPR006220: IPR 002474: IPR000991: IPR006274; KEGG: sma:SAV_6866 carbamoyl phosphate synthase small subunit; PFAM: carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; PRIAM: carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: carbamoyl-phosphate synthase small chain, CPSase domain; glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_004098844.1 COGs: COG0458 carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011761: IPR005483: IPR005479: IPR005481: IPR 005480: IPR011607: IPR006275; KEGG: kse:Ksed_12690 carbamoyl-phosphate synthase large subunit; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: carbamoylphosphate synthetase large chain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; carbamoyl-phosphate synthetase large chain, oligomerisation domain; carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004098845.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR017927: IPR006058: IPR019480; KEGG: ace:Acel_1297 dihydroorotate oxidase B, electron transfer subunit; PFAM: dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: dihydroorotate dehydrogenase electron transfer subunit; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B YP_004098846.1 COGs: COG0167 dihydroorotate dehydrogenase; InterPro IPR001295: IPR012135: IPR005720; KEGG: ace:Acel_1296 dihydroorotate oxidase B, catalytic subunit; PFAM: dihydroorotate oxidase; SPTR: dihydroorotate dehydrogenase 1; TIGRFAM: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein YP_004098847.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2 YP_004098848.1 KEGG: sro:Sros_2812 hypothetical protein; SPTR: uncharacterized protein YP_004098849.1 COGs: COG0194 Guanylate kinase; InterPro IPR008145: IPR008144: IPR020590: IPR017665; KEGG: cfl:Cfla_1850 guanylate kinase; PFAM: guanylate kinase; PRIAM: Guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; SPTR: Guanylate kinase; TIGRFAM: guanylate kinase; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_004098850.1 InterPro IPR003716: IPR006110; KEGG: kra:Krad_2991 DNA-directed RNA polymerase subunit omega; PFAM: RNA polymerase Rpb6; SPTR: DNA-directed RNA polymerase subunit omega; TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_004098851.1 COGs: COG0452 phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382: IPR007085: IPR005252; KEGG: kse:Ksed_12740 phosphopantothenate-cysteine ligase/phosphopantothenoylcysteine decarboxylase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; PRIAM: phosphopantothenate--cysteine ligase; SPTR: phosphopantothenoylcysteine synthase/decarboxylase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_004098852.1 COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: kra:Krad_2989 methionine adenosyltransferase; PFAM: S-adenosylmethionine synthetase; PRIAM: methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_004098853.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; KEGG: tcu:Tcur_3003 primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; SPTR: Primosome assembly protein PriA; TIGRFAM: primosomal protein N' YP_004098854.1 COGs: COG3268 conserved hypothetical protein; InterPro IPR005097; KEGG: gob:Gobs_2039 saccharopine dehydrogenase; PFAM: saccharopine dehydrogenase; PRIAM: saccharopine dehydrogenase (NAD(+), L-glutamate-forming); SPTR: uncharacterized protein; PFAM: saccharopine dehydrogenase YP_004098855.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: nca:Noca_2441 peptide deformylase; PFAM: formylmethionine deformylase; PRIAM: peptide deformylase; SPTR: peptide deformylase; TIGRFAM: peptide deformylase; PFAM: polypeptide deformylase; TIGRFAM: peptide deformylase YP_004098856.1 COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR005794: IPR002376: IPR005793; KEGG: sco:SCO1473 methionyl-tRNA formyltransferase; PFAM: formyl transferase; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: methionyl-tRNA formyltransferase; PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_004098857.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678; KEGG: cfl:Cfla_1856 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: RNA-binding Sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB YP_004098858.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: fre:Franean1_2500 enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase family YP_004098859.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: cai:Caci_3105 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: ribulose-phosphate 3-epimerase; SPTR: ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase YP_004098860.1 COGs: COG3201 Nicotinamide mononucleotide transporter; InterPro IPR006419; KEGG: cef:CE0081 hypothetical protein; PFAM: Nicotinamide mononucleotide transporter PnuC; SPTR: Mononucleotide transporter; TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter; TIGRFAM: nicotinamide mononucleotide transporter PnuC YP_004098861.1 COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR016192: IPR002125: IPR002734: IPR004794; KEGG: kfl:Kfla_5137 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; SPTR: riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD YP_004098862.1 COGs: COG0307 riboflavin synthase alpha chain; InterPro IPR001783; KEGG: sgr:SGR_6090 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: riboflavin synthase; SPTR: riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, subunit alpha; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, subunit alpha YP_004098863.1 COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; InterPro IPR016299: IPR000926: IPR000422; KEGG: cfl:Cfla_1860 GTP cyclohydrolase II; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; SPTR: 3,4-dihydroxy-2-butanone-4-phosphate synthase; GTP cyclohydrolase II; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004098864.1 COGs: COG0054 riboflavin synthase beta-chain; InterPro IPR002180; KEGG: xce:Xcel_1729 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_004098865.1 COGs: COG0140 phosphoribosyl-ATP pyrophosphohydrolase; InterPro IPR008179: IPR021130; KEGG: nda:Ndas_5379 phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase YP_004098866.1 COGs: COG0040 ATP phosphoribosyltransferase; InterPro IPR018198: IPR020621: IPR013820: IPR013115; KEGG: cfl:Cfla_1863 ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase catalytic region; histidine biosynthesis protein HisG domain; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase; PFAM: HisG, C-terminal domain; ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, C-terminal domain; ATP phosphoribosyltransferase YP_004098867.1 KEGG: cfl:Cfla_1864 protein of unknown function DUF2581; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2581) YP_004098868.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tcu:Tcur_3523 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: nitrilotriacetate monooxygenase component B; PFAM: Flavin reductase like domain YP_004098869.1 COGs: COG2807 Cyanate permease; InterPro IPR011701; KEGG: pae:PA1626 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Probable MFS transporter; PFAM: Major Facilitator Superfamily YP_004098870.1 KEGG: ach:Achl_3635 para-aminobenzoate synthase, subunit I; SPTR: Para-aminobenzoate synthase, subunit I YP_004098871.1 COGs: COG0107 imidazoleglycerol-phosphate synthase; InterPro IPR004651: IPR006062; KEGG: kra:Krad_2971 imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004098872.1 InterPro IPR017517: IPR017519; KEGG: saq:Sare_3408 hypothetical protein; SPTR: uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: conserved hypothetical protein TIGR03085; uncharacterized Actinobacterial protein TIGR03083 YP_004098873.1 COGs: COG3981 acetyltransferase; InterPro IPR000182; KEGG: kra:Krad_2568 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004098874.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593: IPR003439: IPR017940: IPR017871: IPR 001140; KEGG: tbi:Tbis_1444 ABC transporter-like protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter YP_004098875.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593: IPR003439: IPR017940: IPR017871: IPR 001140; KEGG: tfu:Tfu_1158 ABC-type multidrug transporter ATPase and permeases; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter ATPase and permeases; PFAM: ABC transporter transmembrane region; ABC transporter YP_004098876.1 COGs: COG0139 phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496; KEGG: ace:Acel_1070 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; PRIAM: phosphoribosyl-AMP cyclohydrolase; SPTR: phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase YP_004098877.1 COGs: COG0147 anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999: IPR006805: IPR015890: IPR005256; KEGG: cai:Caci_5714 anthranilate synthase component I; PFAM: chorismate binding-like; anthranilate synthase component I domain protein; PRIAM: anthranilate synthase; SPTR: anthranilate synthase component I; TIGRFAM: anthranilate synthase component I; PFAM: anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: phage transcriptional regulator, ArpU family; anthranilate synthase component I, non-proteobacterial lineages YP_004098878.1 InterPro IPR019051; KEGG: bcv:Bcav_2226 hypothetical protein; PFAM: Trp biosynthesis associated, transmembrane protein, Oprn/Chp; SPTR: uncharacterized protein; PFAM: tryptophan-associated transmembrane protein (Trp_oprn_chp) YP_004098879.1 KEGG: kfl:Kfla_3064 hypothetical protein; SPTR: anthranilate synthase component I YP_004098880.1 COGs: COG0134 indole-3-glycerol phosphate synthase; InterPro IPR001468: IPR013798; KEGG: xce:Xcel_1499 indole-3-glycerol-phosphate synthase; PFAM: indole-3-glycerol phosphate synthase; PRIAM: indole-3-glycerol-phosphate synthase; SPTR: indole-3-glycerol-phosphate synthase; PFAM: indole-3-glycerol phosphate synthase YP_004098881.1 COGs: COG0133 tryptophan synthase beta chain; InterPro IPR006653: IPR001926: IPR006654; KEGG: cfl:Cfla_1985 tryptophan synthase, beta subunit; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: tryptophan synthase subunit beta; TIGRFAM: tryptophan synthase, beta subunit; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase subunit beta YP_004098882.1 COGs: COG0159 tryptophan synthase alpha chain; InterPro IPR018204: IPR002028; KEGG: mmi:MMAR_2415 tryptophan synthase subunit alpha; PFAM: tryptophan synthase alpha chain; PRIAM: tryptophan synthase; SPTR: tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, subunit alpha YP_004098883.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: kse:Ksed_12920 prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004098884.1 COGs: COG0069 glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase subunit alpha domain protein; PRIAM: glutamate synthase (ferredoxin); SPTR: glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; glutamate synthase central domain; glutamine amidotransferases class-II YP_004098885.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR017896: IPR000759: IPR013027: IPR006005; KEGG: kfl:Kfla_3075 glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: glutamate synthase, NADH/NADPH, small subunit 1; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit YP_004098886.1 COGs: COG0469 pyruvate kinase; InterPro IPR015793: IPR018209: IPR015794: IPR001697; KEGG: cfl:Cfla_1980 pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PRIAM: pyruvate kinase; SPTR: pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase, barrel domain; pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase YP_004098887.1 COGs: COG3707 Response regulator with antiterminator output domain; InterPro IPR001789: IPR005561: IPR008327; KEGG: nca:Noca_3018 response regulator receiver; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain; ANTAR domain YP_004098888.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR001828; KEGG: kfl:Kfla_3081 extracellular ligand-binding receptor; PFAM: extracellular ligand-binding receptor; SPTR: branched-chain amino acid binding protein; PFAM: Receptor family ligand binding region YP_004098889.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: sco:SCO2009 branched-chain amino acid transport permease; PFAM: inner-membrane translocator; SPTR: branched-chain amino acid transport permease; PFAM: Branched-chain amino acid transporter / permease YP_004098890.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: kfl:Kfla_3083 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: branched-chain amino acid transport permease; PFAM: Branched-chain amino acid transporter / permease YP_004098891.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593: IPR003439: IPR018170; KEGG: kfl:Kfla_3084 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004098892.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: kfl:Kfla_3085 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: branched-chain amino acid transport ATP-binding protein; PFAM: ABC transporter YP_004098893.1 KEGG: kfl:Kfla_2533 hypothetical protein; SPTR: uncharacterized protein YP_004098894.1 InterPro IPR000182; KEGG: kra:Krad_2952 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family YP_004098895.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683: IPR003736; KEGG: scb:SCAB_68961 hypothetical protein; PFAM: thioesterase superfamily protein; SPTR: esterase YbdB; PFAM: thioesterase; TIGRFAM: uncharacterized domain 1 YP_004098896.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR002421: IPR008918: IPR002562: IPR001098: IPR 002298: IPR019760: IPR020046: IPR020047: IPR018320; KEGG: kra:Krad_2951 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase family A; TIGRFAM: DNA polymerase I YP_004098897.1 InterPro IPR002797; KEGG: tpr:Tpau_0415 xylose transporter; PFAM: polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis protein YP_004098898.1 InterPro IPR005829; KEGG: saq:Sare_0209 hypothetical protein; SPTR: uncharacterized protein YP_004098899.1 KEGG: ami:Amir_0041 copper resistance protein CopC; SPTR: Copper resistance protein CopC YP_004098900.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: nca:Noca_3000 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004098901.1 InterPro IPR013216; KEGG: amd:AMED_7530 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methylase involved in ubiquinone/menaquinone biosynthesis-like protein; PFAM: methyltransferase domain YP_004098902.1 InterPro IPR000421; KEGG: kfl:Kfla_3096 coagulation factor 5/8 type domain protein; PFAM: coagulation factor 5/8 type domain protein; SPTR: Coagulation factor 5/8 type domain protein; PFAM: Domain of unknown function (DUF3367) YP_004098903.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: kfl:Kfla_3097 acyltransferase 3; PFAM: acyltransferase 3; SPTR: acyltransferase 3; manually curated; PFAM: acyltransferase family YP_004098904.1 KEGG: amd:AMED_7538 hypothetical protein; SPTR: Conserved hypothetical membrane protein YP_004098905.1 KEGG: kfl:Kfla_3099 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3068) YP_004098906.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: kra:Krad_2949 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004098907.1 COGs: COG0539 ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: jde:Jden_1229 30S ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: 30S ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1 YP_004098908.1 COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: art:Arth_0950 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: glycerophosphodiester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase family YP_004098909.1 COGs: COG0237 Dephospho-CoA kinase; InterPro IPR001977: IPR007344; KEGG: art:Arth_2069 dephospho-CoA kinase/protein folding accessory domain-containing protein; PFAM: Dephospho-CoA kinase; protein of unknown function UPF0157; PRIAM: Dephospho-CoA kinase; SPTR: uncharacterized protein coaE; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; Uncharacterised protein family (UPF0157); TIGRFAM: dephospho-CoA kinase YP_004098910.1 COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143; KEGG: rer:RER_26830 lipoate-protein ligase; PFAM: biotin/lipoate A/B protein ligase; SPTR: lipoate-protein ligase; PFAM: Biotin/lipoate A/B protein ligase family YP_004098911.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; InterProIPR014001: IPR001650: IPR001943: IPR014021: IPR 004807: IPR006935; KEGG: kra:Krad_2942 excinuclease ABC subunit B; PFAM: helicase domain protein; type III restriction protein res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase; helicase; SPTR: UvrABC system protein B; TIGRFAM: excinuclease ABC subunit B; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC subunit B YP_004098912.1 COGs: COG0861 membrane protein TerC possibly involved in tellurium resistance; InterPro IPR005496: IPR003838; KEGG: kfl:Kfla_3114 integral membrane protein TerC; PFAM: integral membrane protein TerC; protein of unknown function DUF214; SPTR: transporter membrane protein; PFAM: integral membrane protein TerC family; TIGRFAM: integral membrane protein, TerC family YP_004098913.1 COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620; KEGG: kse:Ksed_13040 predicted permease, DMT superfamily; PFAM: protein of unknown function DUF6 transmembrane; SPTR: integral membrane protein; PFAM: EamA-like transporter family YP_004098914.1 KEGG: dgkA; diacylglycerol kinase; SPTR: diacylglycerol kinase YP_004098915.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: saq:Sare_3342 beta-lactamase domain-containing protein; SPTR: Zn-dependent hydrolase; PFAM: metallo-beta-lactamase superfamily YP_004098916.1 InterPro IPR017517; KEGG: cai:Caci_5617 mycothiol-dependent maleylpyruvate isomerase; SPTR: uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: uncharacterized Actinobacterial protein TIGR03083 YP_004098917.1 COGs: COG3387 glucoamylase and related glycosyl hydrolase; InterPro IPR011613; KEGG: nca:Noca_2323 glycoside hydrolase 15-related; PFAM: glycoside hydrolase 15-related; SPTR: glycoside hydrolase 15-related; PFAM: glycosyl hydrolases family 15 YP_004098918.1 COGs: COG0178 excinuclease ATPase; InterPro IPR003593: IPR003439: IPR017871: IPR004602; KEGG: cfl:Cfla_1949 excinuclease ABC, subunit alpha; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: excinuclease ABC subunit A; TIGRFAM: excinuclease ABC subunit A; PFAM: ABC transporter; TIGRFAM: excinuclease ABC subunit A YP_004098919.1 InterPro IPR017941: IPR006311; KEGG: sro:Sros_6043 ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase-like protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase-like protein; PFAM: Rieske [2Fe-2S] domain YP_004098920.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; InterProIPR000305: IPR003583: IPR001943: IPR001162: IPR 004791: IPR000445; KEGG: kra:Krad_2935 excinuclease ABC subunit C; PFAM: excinuclease ABC subunit C ; excinuclease ABC subunit C ; UvrB/UvrC protein; helix-hairpin-helix motif; SMART: excinuclease ABC subunit C ; DNA-binding protein; SPTR: UvrABC system protein C; TIGRFAM: excinuclease ABC, C subunit; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit YP_004098921.1 COGs: COG1660 P-loop-containing kinase; InterPro IPR005337; KEGG: sco:SCO1952 hypothetical protein; SPTR: UPF0042 nucleotide-binding protein JNB_03525; PFAM: P-loop ATPase protein family YP_004098922.1 COGs: COG0391 conserved hypothetical protein; InterPro IPR002882: IPR010119; KEGG: jde:Jden_1254 protein of unknown function UPF0052 and CofD; PFAM: protein of unknown function UPF0052 and CofD; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related YP_004098923.1 COGs: COG1481 conserved hypothetical protein; InterPro IPR018478: IPR003802; KEGG: sma:SAV_6294 sporulation regulatory protein; PFAM: protein of unknown function DUF199; sporulation regulator WhiA-like; SPTR: sporulation regulatory protein; PFAM: sporulation Regulator WhiA N terminal; sporulation Regulator WhiA C terminal domain; TIGRFAM: conserved hypothetical protein YP_004098924.1 COGs: COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020832: IPR020830: IPR020831: IPR020828: IPR 020829: IPR006424; KEGG: kfl:Kfla_3261 glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase YP_004098925.1 COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576: IPR015911; KEGG: kse:Ksed_13120 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: phosphoglycerate kinase; SPTR: phosphoglycerate kinase; PFAM: phosphoglycerate kinase YP_004098926.1 COGs: COG0149 triosephosphate isomerase; InterPro IPR000652: IPR020861; KEGG: aau:AAur_2090 triosephosphate isomerase; PFAM: triosephosphate isomerase; PRIAM: triose-phosphate isomerase; SPTR: triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_004098927.1 InterPro IPR004692; KEGG: aau:AAur_2091 preprotein translocase subunit SecG; PFAM: Preprotein translocase SecG subunit; SPTR: triosephosphate isomerase; TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_004098928.1 InterPro IPR018527; KEGG: kra:Krad_2927 electron transport protein; SPTR: electron transporter YP_004098929.1 COGs: COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase; InterPro IPR005900; KEGG: xce:Xcel_1553 6-phosphogluconolactonase; PRIAM: 6-phosphogluconolactonase; SPTR: 6-phosphogluconolactonase; TIGRFAM: 6-phosphogluconolactonase; TIGRFAM: 6-phosphogluconolactonase YP_004098930.1 COGs: COG3429 glucose-6-P dehydrogenase subunit; InterPro IPR019297; KEGG: kra:Krad_2925 OpcA protein; PFAM: glucose-6-phosphate dehydrogenase subunit; SPTR: OpcA protein; PFAM: glucose-6-phosphate dehydrogenase subunit; TIGRFAM: opcA protein YP_004098931.1 COGs: COG0364 glucose-6-phosphate 1-dehydrogenase; InterPro IPR001282: IPR019796; KEGG: kra:Krad_2924 glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase; PRIAM: glucose-6-phosphate dehydrogenase; SPTR: glucose-6-phosphate 1-dehydrogenase; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase, C-terminal domain; glucose-6-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase YP_004098932.1 COGs: COG0166 glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: ach:Achl_1836 phosphoglucose isomerase (PGI); PFAM: phosphoglucose isomerase (PGI); SPTR: glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase YP_004098933.1 COGs: COG0176 transaldolase; InterPro IPR018225: IPR014634: IPR001585: IPR004732; KEGG: ach:Achl_1837 transaldolase; PFAM: transaldolase; SPTR: transaldolase; TIGRFAM: transaldolase; PFAM: transaldolase; TIGRFAM: transaldolase, mycobacterial type YP_004098934.1 COGs: COG0021 transketolase; InterProIPR005474: IPR020826: IPR005475: IPR005476: IPR 005478; KEGG: sgr:SGR_4907 transketolase; PFAM: transketolase domain-containing protein; transketolase; SPTR: transketolase; TIGRFAM: transketolase; PFAM: transketolase, thiamine diphosphate binding domain; transketolase, C-terminal domain; transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast YP_004098935.1 COGs: COG0109 polyprenyltransferase (cytochrome oxidase assembly factor); InterPro IPR000537: IPR006369; KEGG: kse:Ksed_13220 protoheme IX farnesyltransferase; PFAM: UbiA prenyltransferase; SPTR: Protoheme IX farnesyltransferase; TIGRFAM: protoheme IX farnesyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: protoheme IX farnesyltransferase YP_004098936.1 COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182: IPR020476: IPR020084: IPR000086; KEGG: kfl:Kfla_4957 NUDIX hydrolase; PFAM: NUDIX hydrolase; GCN5-related N-acetyltransferase; SPTR: NUDIX hydrolase; PFAM: acetyltransferase (GNAT) family; NUDIX domain YP_004098937.1 COGs: COG1612 Uncharacterized protein required for cytochrome oxidase assembly; InterPro IPR003780; KEGG: kse:Ksed_13300 uncharacterized protein required for cytochrome oxidase assembly; PFAM: cytochrome oxidase assembly; SPTR: cytochrome C oxidase subunit XV assembly protein; PFAM: cytochrome oxidase assembly protein YP_004098938.1 KEGG: sro:Sros_6098 hypothetical protein; SPTR: uncharacterized protein YP_004098939.1 InterPro IPR013525; KEGG: kse:Ksed_13310 ABC-type multidrug transporter permease; PFAM: ABC transporter; SPTR: ABC-type multidrug transporter permease; PFAM: ABC transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_004098940.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: kra:Krad_2919 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter ATPase componen; PFAM: ABC transporter YP_004098941.1 COGs: COG0688 phosphatidylserine decarboxylase; InterPro IPR004428: IPR003817; KEGG: gob:Gobs_4178 phosphatidylserine decarboxylase related protein; PFAM: phosphatidylserine decarboxylase-related; PRIAM: phosphatidylserine decarboxylase; SPTR: phosphatidylserine decarboxylase proenzyme; PFAM: phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein YP_004098942.1 COGs: COG1183 phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4179 CDP-diacylglycerol/serine O-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase YP_004098943.1 COGs: COG2345 transcriptional regulator protein; KEGG: kse:Ksed_13330 predicted transcriptional regulator; SPTR: DNA-binding protein; PFAM: HTH domain YP_004098944.1 COGs: COG0719 ABC-type transporter involved in Fe-S cluster assembly permease; InterPro IPR000825: IPR010231; KEGG: kra:Krad_2917 FeS assembly protein SufB; PFAM: SufBD protein; SPTR: uncharacterized protein; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB YP_004098945.1 COGs: COG0719 ABC-type transporter involved in Fe-S cluster assembly permease; InterPro IPR000825: IPR011542; KEGG: kse:Ksed_13350 iron-regulated ABC transporter permease SufD; PFAM: SufBD protein; SPTR: iron-regulated ABC-type transporter; TIGRFAM: FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1 YP_004098946.1 COGs: COG0396 ABC-type transporter involved in Fe-S cluster assembly ATPase component; InterPro IPR003593: IPR003439: IPR010230; KEGG: bcv:Bcav_2337 FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_004098947.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: nda:Ndas_2959 cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; SPTR: Cysteine desulphurases, SufS; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily YP_004098948.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871: IPR011341; KEGG: srt:Srot_2325 NifU family SUF system FeS assembly protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: uncharacterized protein; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family YP_004098949.1 COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: bcv:Bcav_2334 protein of unknown function DUF59; PFAM: protein of unknown function DUF59; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF59 YP_004098950.1 KEGG: kfl:Kfla_3285 hypothetical protein; SPTR: uncharacterized protein YP_004098951.1 COGs: COG2321 metalloprotease; InterPro IPR007343; KEGG: aau:AAur_2109 zinc metallopeptidase; PFAM: protein of unknown function zinc metallopeptidase; SPTR: metalloprotease; PFAM: neutral zinc metallopeptidase YP_004098952.1 InterPro IPR000408: IPR001608; KEGG: nca:Noca_4674 alanine racemase domain-containing protein; PFAM: alanine racemase domain protein; SPTR: alanine racemase domain protein; PFAM: alanine racemase, N-terminal domain YP_004098953.1 COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: kfl:Kfla_7010 methicillin resistance protein; PFAM: methicillin resistance protein; SPTR: methicillin resistance protein; PFAM: FemAB family YP_004098954.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439: IPR017871; KEGG: kse:Ksed_13460 ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP binding protein; PFAM: ABC transporter YP_004098955.1 KEGG: ami:Amir_1238 hypothetical protein; SPTR: uncharacterized protein YP_004098956.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593: IPR003439: IPR017940: IPR017871: IPR 001140; KEGG: kfl:Kfla_3305 ABC transporter; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter ATPase and permease; PFAM: ABC transporter transmembrane region; ABC transporter YP_004098957.1 KEGG: sna:Snas_5699 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF664) YP_004098958.1 COGs: COG3346 conserved hypothetical protein; InterPro IPR002994; KEGG: kse:Ksed_13470 hypothetical protein; SPTR: uncharacterized protein; PFAM: SURF1 family YP_004098959.1 COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterProIPR006638: IPR018062: IPR000385: IPR007197: IPR 010505: IPR013483; KEGG: cai:Caci_2295 molybdenum cofactor biosynthesis protein A; PFAM: molybdenum cofactor synthesis protein; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial YP_004098960.1 KEGG: tcu:Tcur_2268 hypothetical protein; SPTR: uncharacterized protein YP_004098961.1 KEGG: bcv:Bcav_2323 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3099) YP_004098962.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR011284; KEGG: mlu:Mlut_11580 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-[acyl-carrier protein] reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_004098963.1 COGs: COG0623 enoyl-(acyl-carrier-protein); InterPro IPR002198; KEGG: cfl:Cfla_1687 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: enoyl-(acyl carrier protein) reductase; PFAM: short chain dehydrogenase YP_004098964.1 COGs: COG0560 phosphoserine phosphatase; InterProIPR002912: IPR005834: IPR004469: IPR006383: IPR 006385; KEGG: kfl:Kfla_3704 phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein; PRIAM: phosphoserine phosphatase; SPTR: phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; manually curated; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB YP_004098965.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; KEGG: kfl:Kfla_3670 coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein; SPTR: uncharacterized protein; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable F420-dependent oxidoreductase, MSMEG_2906 family YP_004098966.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005836: IPR005835: IPR011831; KEGG: kra:Krad_2901 glucose-1-phosphate adenylyltransferase; PFAM: nucleotidyl transferase; SPTR: glucose-1-phosphate adenylyltransferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; PFAM: nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase YP_004098967.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296: IPR011875; KEGG: kra:Krad_2900 glycogen synthase; PFAM: glycosyl transferase group 1; SPTR: Possible glycosyltransferase; TIGRFAM: glycogen synthase; PFAM: glycosyl transferases group 1; TIGRFAM: glycogen synthase, Corynebacterium family YP_004098968.1 KEGG: cfl:Cfla_1719 hypothetical protein; SPTR: uncharacterized protein YP_004098969.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: nml:Namu_4797 LmbE family protein; PFAM: LmbE family protein; SPTR: uncharacterized protein; PFAM: GlcNAc-PI de-N-acetylase YP_004098970.1 KEGG: kse:Ksed_13550 hypothetical protein; SPTR: uncharacterized protein YP_004098971.1 COGs: COG1119 ABC-type molybdenum transporter ATPase component/photorepair protein PhrA; InterPro IPR003593: IPR003439; KEGG: kse:Ksed_13560 ABC-type molybdenum transporter ATPase component/photorepair protein PhrA; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type molybdenum transporter ATPase component/photorepair protein PhrA; PFAM: ABC transporter YP_004098972.1 COGs: COG1585 membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: kra:Krad_3088 protein of unknown function DUF107; PFAM: protein of unknown function DUF107; SPTR: integral membrane protein; PFAM: NfeD-like YP_004098973.1 COGs: COG0330 membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107: IPR001972: IPR018080; KEGG: bcv:Bcav_2313 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: secreted protein; PFAM: SPFH domain / Band 7 family YP_004098974.1 InterPro IPR002781; KEGG: nfa:nfa3090 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004098975.1 InterPro IPR002781; KEGG: tfu:Tfu_1919 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004098976.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: kse:Ksed_13580 rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: RRNA methyltransferase; PFAM: SpoU rRNA methylase family YP_004098977.1 KEGG: nca:Noca_2347 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3037) YP_004098978.1 KEGG: kse:Ksed_13600 hypothetical protein; SPTR: uncharacterized protein YP_004098979.1 InterPro IPR011701; KEGG: kfl:Kfla_7034 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004098980.1 COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: kra:Krad_3699 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase; PFAM: phosphoglycerate mutase family YP_004098981.1 COGs: COG0063 sugar kinase; InterPro IPR000631; KEGG: kra:Krad_3700 carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; SPTR: carbohydrate kinase, YjeF related protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: carbohydrate kinase; TIGRFAM: yjeF C-terminal region, hydroxyethylthiazole kinase-related YP_004098982.1 COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR002933: IPR011650; KEGG: bcv:Bcav_2253 hypothetical protein; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: uncharacterized protein; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain YP_004098983.1 KEGG: kra:Krad_1816 hypothetical protein; SPTR: uncharacterized protein YP_004098984.1 KEGG: ske:Sked_04540 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1396) YP_004098985.1 KEGG: bfa:Bfae_16260 hypothetical protein; SPTR: uncharacterized protein YP_004098986.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471: IPR018170: IPR001395; KEGG: nca:Noca_2622 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; manually curated; PFAM: Aldo/keto reductase family YP_004098987.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048: IPR019951; KEGG: saq:Sare_2317 luciferase family protein; PFAM: Luciferase-like, subgroup; SPTR: FMN-dependent monooxygenase; TIGRFAM: F420-dependent oxidoreductase; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable F420-dependent oxidoreductase, Rv3520c family YP_004098988.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; InterPro IPR003824; KEGG: sna:Snas_4503 undecaprenol kinase; PFAM: bacitracin resistance protein BacA; SPTR: undecaprenyl pyrophosphate phosphatase; TIGRFAM: undecaprenol kinase; PFAM: bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP YP_004098989.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523: IPR004488; KEGG: sgr:SGR_5836 ion transporter; PFAM: Mg2 transporter protein CorA family protein; SPTR: transporter; TIGRFAM: magnesium and cobalt transporter CorA; PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transporter (corA) YP_004098990.1 COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: kra:Krad_1833 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase; PFAM: phosphoglycerate mutase family; TIGRFAM: probable phosphomutase, MSMEG_4193 family YP_004098991.1 KEGG: kra:Krad_1834 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3090); TIGRFAM: conserved hypothetical protein YP_004098992.1 KEGG: sen:SACE_2204 phosphatidylinositol 3-and 4-kinase, catalytic; SPTR: phosphatidylinositol 3-and 4-kinase, catalytic; PFAM: phosphatidylinositol 3- and 4-kinase; TIGRFAM: conserved hypothetical protein YP_004098993.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803: IPR017812; KEGG: ske:Sked_20970 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; manually curated; PFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase; cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase YP_004098994.1 InterPro IPR008492; KEGG: sco:SCO1662 hypothetical protein; SPTR: uncharacterized protein; PFAM: PAC2 family YP_004098995.1 COGs: COG1410 methionine synthase I cobalamin-binding domain; InterProIPR003726: IPR000489: IPR004223: IPR006158: IPR 003759: IPR011822; KEGG: nca:Noca_2631 B12-dependent methionine synthase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; Vitamin B12 dependent methionine synthase activation region; SPTR: methionine synthase (B12-dependent); TIGRFAM: methionine synthase; PFAM: Pterin binding enzyme; Vitamin B12 dependent methionine synthase, activation domain; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase YP_004098996.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834: IPR006402; KEGG: bcv:Bcav_2245 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; SPTR: Hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004098997.1 COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524: IPR004839; KEGG: msm:MSMEG_2104 GntR-family protein transcriptional regulator; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; SPTR: GntR-family protein transcriptional regulator; PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family YP_004098998.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590: IPR010061; KEGG: msv:Mesil_1872 methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase YP_004098999.1 COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: fal:FRAAL1423 hypothetical protein; PFAM: aminotransferase class-III; SPTR: Aminotransferase class-III; PFAM: Aminotransferase class-III YP_004099000.1 COGs: COG2887 RecB family exonuclease; KEGG: kfl:Kfla_3207 RecB family exonuclease-like protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2800) YP_004099001.1 COGs: COG1994 Zn-dependent protease; InterPro IPR000644: IPR008915; KEGG: xce:Xcel_1483 peptidase M50; PFAM: peptidase M50; SPTR: peptidase; PFAM: peptidase family M50 YP_004099002.1 InterPro IPR000424; KEGG: nca:Noca_2477 single-strand binding protein/primosomal replication protein N; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: uncharacterized protein; PFAM: Single-strand binding protein family YP_004099003.1 COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: cfl:Cfla_2005 tRNA (adenine-N(1)-)-methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: uncharacterized protein; PFAM: tRNA methyltransferase complex GCD14 subunit YP_004099004.1 COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003593: IPR001984: IPR003960: IPR003959; KEGG: nca:Noca_2639 vesicle-fusing ATPase; PFAM: ATPase AAA central domain protein; SMART: ATPase AAA; SPTR: Proteasome-associated ATPase; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: proteasome ATPase YP_004099005.1 KEGG: lxx:Lxx17840 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3054) YP_004099006.1 COGs: COG0462 phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: kfl:Kfla_2836 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: ribose-phosphate diphosphokinase; SPTR: ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004099007.1 InterPro IPR004347; KEGG: kra:Krad_1871 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; SPTR: uncharacterized protein; PFAM: Pup-ligase protein; TIGRFAM: proteasome accessory factor PafA2 YP_004099008.1 InterPro IPR008515; KEGG: ach:Achl_1918 protein of unknown function DUF797; PFAM: protein of unknown function DUF797; SPTR: uncharacterized protein; TIGRFAM: protein of unknown function DUF797; PFAM: Pup-like protein; TIGRFAM: ubiquitin-like protein Pup YP_004099009.1 COGs: COG0638 20S proteasome alpha and beta subunits; InterPro IPR001353; KEGG: cfl:Cfla_2001 20S proteasome A and B subunits; PFAM: 20S proteasome A and B subunits; SPTR: 20S proteasome beta-subunit; PFAM: Proteasome subunit; TIGRFAM: proteasome subunit beta, bacterial type YP_004099010.1 COGs: COG0638 20S proteasome alpha and beta subunits; InterPro IPR001353; KEGG: ske:Sked_20860 20S proteasome subunit (alpha or beta); PFAM: 20S proteasome A and B subunits; SPTR: 20S proteasome alpha-subunit; PFAM: Proteasome subunit; TIGRFAM: proteasome, subunit alpha, bacterial type YP_004099011.1 KEGG: cai:Caci_1250 cellulose-binding protein; SPTR: cellulose-binding protein YP_004099012.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sma:SAV_726 oxidoreductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: oxidoreductase; PFAM: NAD dependent epimerase/dehydratase family YP_004099013.1 InterPro IPR004347; KEGG: cai:Caci_2428 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; SPTR: uncharacterized protein; PFAM: Pup-ligase protein; TIGRFAM: proteasome accessory factor PafA YP_004099014.1 COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: kse:Ksed_13970 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004099015.1 COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: kse:Ksed_13980 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: peptidylprolyl isomerase FKBP-type; PRIAM: peptidylprolyl isomerase; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004099016.1 KEGG: kra:Krad_1878 hypothetical protein; SPTR: uncharacterized protein YP_004099017.1 COGs: COG2378 transcriptional regulator protein; KEGG: kra:Krad_1879 transcriptional regulator-like; SPTR: transcriptional regulator-like protein YP_004099018.1 COGs: COG2378 transcriptional regulator protein; KEGG: kra:Krad_1880 hypothetical protein; SPTR: uncharacterized protein YP_004099019.1 InterPro IPR006312: IPR003369; KEGG: ckp:ckrop_0908 sec-independent protein translocase protein; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: Sec-independent protein translocase protein; TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004099020.1 COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033: IPR019822; KEGG: ske:Sked_18520 twin arginine targeting protein translocase subunit TatC; PFAM: Sec-independent periplasmic protein translocase; SPTR: Sec-independent protein translocase protein TatC; TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_004099021.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206: IPR005218; KEGG: sro:Sros_5857 hypothetical protein; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase; SPTR: uncharacterized protein; PFAM: diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family YP_004099022.1 COGs: COG4581 Superfamily II RNA helicase; InterProIPR014001: IPR001650: IPR014021: IPR011545: IPR 012961; KEGG: sgr:SGR_5873 ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase; DSH domain protein; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DSHCT (NUC185) domain; DEAD/DEAH box helicase YP_004099023.1 COGs: COG0258 5'-3' exonuclease (including N-terminal domain of PolI); InterPro IPR002421: IPR008918: IPR020046: IPR020047; KEGG: cfl:Cfla_0590 5'-3' exonuclease, N-terminal resolvase-like domain protein; PFAM: 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; SPTR: 5'-3' exonuclease; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain YP_004099024.1 COGs: COG1522 transcriptional regulators; InterPro IPR019888: IPR000485: IPR019885: IPR019887; KEGG: scb:SCAB_75801 AsnC family transcriptional regulator; PFAM: transcription regulator AsnC-type-like; SMART: transcription regulator AsnC-type; SPTR: AsnC-family transcriptional regulator; PFAM: IclR helix-turn-helix domain; AsnC family YP_004099025.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004812; KEGG: xal:XALc_0877 Probable major facilitator superfamily. transmembrane protein; PFAM: major facilitator superfamily MFS_1; SPTR: Probable major facilitator superfamily. transmembrane protein; TIGRFAM: drug resistance transporter Bcr/CflA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter Bcr/CflA subfamily YP_004099026.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214: IPR004369; KEGG: sco:SCO2058 transcriptional regulatory protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: transcriptional regulator; TIGRFAM: ybaK/ebsC protein; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein YP_004099027.1 InterPro IPR001647; KEGG: sen:SACE_6360 TetR/AcrR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator (TetR/AcrR family); manually curated; PFAM: Bacterial regulatory proteins, tetR family YP_004099028.1 COGs: COG1509 lysine 2 3-aminomutase; InterPro IPR007197; KEGG: kfl:Kfla_3605 lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM protein; PRIAM: lysine 2,3-aminomutase; SPTR: L-lysine 2,3-aminomutase; TIGRFAM: KamA family protein YP_004099029.1 KEGG: kfl:Kfla_3604 L-erythro-3,5-diaminohexanoate dehydrogenase; SPTR: Zn-dependent alcohol dehydrogenase and related dehydrogenase protein; PFAM: Zinc-binding dehydrogenase YP_004099030.1 InterPro IPR015130; KEGG: kfl:Kfla_3602 D-lysine 56-aminomutase subunit alpha; PFAM: D-lysine 56-aminomutase alpha subunit; SPTR: lysine 5,6-aminomutase subunit alpha; PFAM: D-lysine 5,6-aminomutase subunit alpha YP_004099031.1 InterPro IPR006158; KEGG: nca:Noca_2664 beta-lysine 5,6-aminomutase subunit beta / D-lysine 5,6-aminomutase subunit beta; PFAM: cobalamin B12-binding domain protein; SPTR: beta-lysine 5,6-aminomutase beta subunit / D-lysine 5,6-aminomutase subunit beta; PFAM: B12 binding domain YP_004099032.1 InterPro IPR006683; KEGG: sna:Snas_3948 3-aminobutyryl-CoA ammonia-lyase; PFAM: thioesterase superfamily protein; SPTR: uncharacterized protein; PFAM: thioesterase YP_004099033.1 COGs: COG0815 Apolipoprotein N-acyltransferase; InterPro IPR003010: IPR004563; KEGG: gob:Gobs_2703 apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: polyprenol phosphate mannosyl transferase 2; TIGRFAM: apolipoprotein N-acyltransferase; PFAM: carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase YP_004099034.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: kse:Ksed_14090 glycosyl transferase; PFAM: glycosyl transferase family 2; PRIAM: Dolichyl-phosphate beta-D-mannosyltransferase; SPTR: glycosyl transferase; PFAM: glycosyl transferase family 2 YP_004099035.1 COGs: COG3030 protein affecting phage T7 exclusion by the F plasmid; InterPro IPR007313; KEGG: kfl:Kfla_3598 FxsA cytoplasmic membrane protein; PFAM: FxsA cytoplasmic membrane protein; SPTR: FxsA cytoplasmic membrane protein; PFAM: FxsA cytoplasmic membrane protein YP_004099036.1 KEGG: kse:Ksed_14110 hypothetical protein; SPTR: uncharacterized protein YP_004099037.1 COGs: COG2270 Permease of the major facilitator superfamily; InterPro IPR011701; KEGG: kse:Ksed_14630 major facilitator superfamily permease; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily permease; PFAM: Vacuole effluxer Atg22 like YP_004099038.1 KEGG: ahe:Arch_0138 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004099039.1 COGs: COG3559 exporter of polyketide antibiotics; KEGG: tbi:Tbis_3202 hypothetical protein; SPTR: uncharacterized protein YP_004099040.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: tbi:Tbis_3201 ABC transporter-like protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004099041.1 KEGG: cwo:Cwoe_5391 hypothetical protein; SPTR: transcriptional regulator YP_004099042.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: ach:Achl_1142 23S rRNA methyluridine methyltransferase; PFAM: (uracil-5)-methyltransferase; SPTR: 23S rRNA (uracil-5-)-methyltransferase RumB; PFAM: tRNA (uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumB YP_004099043.1 COGs: COG4427 conserved hypothetical protein; InterPro IPR000276: IPR011200; KEGG: amd:AMED_1098 hypothetical protein; PFAM: protein of unknown function UCP012608; SPTR: Uncharacterized conserved protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2332) YP_004099044.1 COGs: COG0366 glycosidase; InterPro IPR006589: IPR006047; KEGG: nca:Noca_1267 alpha amylase, catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: alpha amylase, catalytic region; PFAM: alpha amylase, catalytic domain YP_004099045.1 COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: ske:Sked_33230 hypothetical protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: Filamentation induced by cAMP protein Fic; PFAM: Fic/DOC family YP_004099046.1 COGs: COG0009 translation factor (SUA5); InterPro IPR006070: IPR004388; KEGG: ami:Amir_4990 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: uncharacterized protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004099047.1 KEGG: nca:Noca_0955 hypothetical protein; SPTR: uncharacterized protein YP_004099048.1 COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: gob:Gobs_2153 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; TIGRFAM: FMN reductase, MsuE subfamily YP_004099049.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: ske:Sked_18700 flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like, subgroup; SPTR: Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like monooxygenase YP_004099050.1 COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: ami:Amir_6302 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, , group 3 YP_004099051.1 COGs: COG0384 epimerase PhzC/PhzF homolog; InterPro IPR001412: IPR003719; KEGG: bpt:Bpet1856 hypothetical protein; PFAM: Phenazine biosynthesis PhzC/PhzF protein; SPTR: Conserved hypotheticals protein; TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis-like protein; TIGRFAM: phenazine biosynthesis protein PhzF family YP_004099052.1 COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: gob:Gobs_1372 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase family protein; PFAM: phosphoglycerate mutase family YP_004099053.1 InterPro IPR016602; KEGG: nml:Namu_1357 hypothetical protein; SPTR: uncharacterized protein YP_004099054.1 COGs: COG1003 glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR003437: IPR020580; KEGG: kse:Ksed_14930 glycine dehydrogenase; PFAM: glycine cleavage system P-protein-like; SPTR: glycine dehydrogenase [decarboxylating]; TIGRFAM: glycine dehydrogenase; PFAM: glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating) YP_004099055.1 InterPro IPR000551; KEGG: aau:AAur_1684 hypothetical protein; SMART: regulatory protein MerR; SPTR: uncharacterized protein YP_004099056.1 COGs: COG1259 conserved hypothetical protein; InterPro IPR003729; KEGG: nca:Noca_2711 hypothetical protein; PFAM: protein of unknown function DUF151; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, COG1259 YP_004099057.1 InterPro IPR000551; KEGG: nca:Noca_2712 regulatory protein, MerR; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: uncharacterized protein; manually curated; PFAM: MerR family regulatory protein YP_004099058.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: kfl:Kfla_3173 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: uncharacterized protein; manually curated; PFAM: FHA domain YP_004099059.1 COGs: COG0509 glycine cleavage system protein H (lipoate-binding); InterPro IPR003016: IPR002930: IPR017453; KEGG: kse:Ksed_14980 glycine cleavage system protein H; PFAM: glycine cleavage H-protein; SPTR: glycine cleavage system protein H; TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein YP_004099060.1 COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: xce:Xcel_1737 protein of unknown function DUF881; PFAM: protein of unknown function DUF881; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF881) YP_004099061.1 COGs: COG3856 conserved hypothetical protein (small basic protein); InterPro IPR009709; KEGG: ske:Sked_18240 uncharacterized conserved protein (small basic protein); PFAM: protein of unknown function DUF1290; SPTR: membrane protein; PFAM: protein of unknown function (DUF1290) YP_004099062.1 COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: sco:SCO1387 membrane associated protein; PFAM: protein of unknown function DUF881; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF881) YP_004099063.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR000462: IPR004570; KEGG: sma:SAV_6976 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: phosphatidylglycerophosphate synthase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004099064.1 COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: nca:Noca_4623 YibE/F family protein; PFAM: YibE/F family protein; SPTR: YibE/F family protein; PFAM: YibE/F-like protein YP_004099065.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: rxy:Rxyl_2414 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004099066.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: fre:Franean1_3719 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: pyruvate carboxyltransferase; PFAM: HMGL-like YP_004099067.1 COGs: COG1335 amidase related to nicotinamidase; InterPro IPR003881: IPR000868; KEGG: sro:Sros_6622 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family YP_004099068.1 COGs: COG0146 N-methylhydantoinase B/acetone carboxylase subunit alpha; InterPro IPR003692; KEGG: gbr:Gbro_2859 5-oxoprolinase (ATP-hydrolyzing); PFAM: hydantoinase B/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: 5-oxoprolinase (ATP-hydrolyzing); PFAM: hydantoinase B/oxoprolinase YP_004099069.1 COGs: COG0145 N-methylhydantoinase A/acetone carboxylase subunit beta; InterPro IPR008040: IPR002821; KEGG: gbr:Gbro_2860 5-oxoprolinase (ATP-hydrolyzing); PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: 5-oxoprolinase (ATP-hydrolyzing); PFAM: hydantoinase/oxoprolinase; hydantoinase/oxoprolinase N-terminal region YP_004099070.1 COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: sro:Sros_6621 formyl-CoA transferase; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; PRIAM: Formyl-CoA transferase; SPTR: Formyl-CoA transferase; PFAM: CoA-transferase family III YP_004099071.1 COGs: COG1802 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: pzu:PHZ_c2130 transcriptional regulator, GntR family; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004099072.1 COGs: COG1160 GTPase; InterProIPR003593: IPR006073: IPR016484: IPR002917: IPR 005225; KEGG: kra:Krad_3115 GTP-binding protein EngA; PFAM: GTP-binding protein HSR1-related; SMART: ATPase AAA; SPTR: GTP-binding protein EngA; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain YP_004099073.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: aau:AAur_1675 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acylglycerol-3-phosphate O-acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004099074.1 COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: ske:Sked_19860 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase YP_004099075.1 COGs: COG0287 prephenate dehydrogenase; InterPro IPR003099: IPR002912; KEGG: kra:Krad_3118 prephenate dehydrogenase; PFAM: prephenate dehydrogenase; amino acid-binding ACT domain protein; SPTR: prephenate dehydrogenase; PFAM: prephenate dehydrogenase; ACT domain YP_004099076.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942: IPR018496: IPR006145: IPR000748; KEGG: kra:Krad_3120 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase YP_004099077.1 COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: tbi:Tbis_1492 chromosome segregation and condensation protein, ScpB; PFAM: chromosome segregation and condensation protein ScpB; SPTR: uncharacterized protein; TIGRFAM: segregation and condensation protein B; PFAM: transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B YP_004099078.1 COGs: COG1354 conserved hypothetical protein; InterPro IPR003768; KEGG: kfl:Kfla_5114 chromosome segregation and condensation protein ScpA; PFAM: chromosome segregation and condensation protein ScpA; SPTR: uncharacterized protein; PFAM: ScpA/B protein YP_004099079.1 COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: kra:Krad_3138 cobyrinic acid ac-diamide synthase; SPTR: partitioning or sporulation protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004099080.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104: IPR011932; KEGG: nca:Noca_2489 tyrosine recombinase XerD; PFAM: integrase; integrase domain protein SAM domain protein; SPTR: Tyrosine recombinase; TIGRFAM: tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: tyrosine recombinase XerD YP_004099081.1 COGs: COG0686 alanine dehydrogenase; InterPro IPR007886: IPR007698: IPR008141; KEGG: kfl:Kfla_5119 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; PRIAM: alanine dehydrogenase; SPTR: alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT, C-terminal domain; alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase YP_004099082.1 KEGG: amd:AMED_8598 hypothetical protein; SPTR: Inner-membrane translocator YP_004099083.1 KEGG: cfl:Cfla_0488 hypothetical protein; SPTR: Possible conserved transmembrane protein YP_004099084.1 COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR006195: IPR004516: IPR002314: IPR004154: IPR 015807; KEGG: kfl:Kfla_4391 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); anticodon-binding domain protein; PRIAM: histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_004099085.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: kse:Ksed_15250 Zn-dependent hydrolase, glyoxylase; SPTR: Possible hydrolase; PFAM: metallo-beta-lactamase superfamily YP_004099086.1 COGs: COG0652 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: cfl:Cfla_1804 peptidyl-prolyl cis-trans isomerase cyclophilin type; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; SPTR: peptidyl-prolyl cis-trans isomerase B; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004099087.1 KEGG: lbc:LACBIDRAFT_319933 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004099088.1 InterPro IPR007139; KEGG: kra:Krad_3046 protein of unknown function DUF349; PFAM: protein of unknown function DUF349; SPTR: uncharacterized protein; manually curated; PFAM: Domain of Unknown Function (DUF349) YP_004099089.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR003607: IPR006674: IPR007685: IPR004095: IPR 002912: IPR004811; KEGG: cfl:Cfla_1801 (p)ppGpp synthetase I, SpoT/RelA; PFAM: RelA/SpoT domain protein; metal-dependent phosphohydrolase HD sub domain; TGS domain-containing protein; amino acid-binding ACT domain protein; PRIAM: GTP diphosphokinase; SMART: metal-dependent phosphohydrolase HD region; SPTR: ppGpp synthetase; TIGRFAM: RelA/SpoT family protein; PFAM: HD domain; ACT domain; TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004099090.1 COGs: COG0503 adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR000836: IPR005764; KEGG: kse:Ksed_15290 adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: adenine phosphoribosyltransferase; TIGRFAM: adenine phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase YP_004099091.1 COGs: COG0341 Preprotein translocase subunit SecF; InterPro IPR003335: IPR005665; KEGG: kse:Ksed_15300 protein translocase subunit SecF; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: protein export protein SecF; TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family; PFAM: protein export membrane protein; TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF YP_004099092.1 COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR005791: IPR003335; KEGG: kse:Ksed_15310 protein-export membrane protein SecD; SPTR: SecD; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; PFAM: protein export membrane protein; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family YP_004099093.1 COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: nca:Noca_2388 protein translocase subunit YajC; PFAM: YajC family protein; SPTR: protein export protein SecD; TIGRFAM: preprotein translocase subunit YajC; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase subunit YajC YP_004099094.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; InterProIPR008824: IPR003959: IPR008823: IPR003593: IPR 004605; KEGG: kse:Ksed_15320 Holliday junction DNA helicase subunit RuvB; PFAM: ATPase AAA central domain protein; Holliday junction DNA helicase RuvB domain; SMART: AAA ATPase; SPTR: Holliday junction DNA helicase RuvB; TIGRFAM: Holliday junction DNA helicase RuvB; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_004099095.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterPro IPR013849: IPR011114: IPR003583: IPR000085; KEGG: tcu:Tcur_2110 Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; RuvA domain protein; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, Ruvsubunit alpha YP_004099096.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176: IPR020563; KEGG: sro:Sros_6113 crossover junction endodeoxyribonuclease; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_004099097.1 COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: sna:Snas_2629 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein JNB_02440; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family YP_004099098.1 COGs: COG0311 glutamine amidotransferase involved in pyridoxine biosynthesis; InterPro IPR002161: IPR021196; KEGG: nca:Noca_2382 SNO glutamine amidotransferase; PFAM: SNO glutamine amidotransferase; SPTR: glutamine amidotransferase subunit pdxT; TIGRFAM: SNO glutamine amidotransferase; PFAM: SNO glutamine amidotransferase family; TIGRFAM: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 YP_004099099.1 KEGG: afw:Anae109_2849 hypothetical protein; SPTR: uncharacterized protein YP_004099100.1 COGs: COG0214 pyridoxine biosynthesis enzyme; InterPro IPR001852; KEGG: kfl:Kfla_4427 pyridoxine biosynthesis protein; PFAM: Vitamin B6 biosynthesis protein; SPTR: pyridoxal biosynthesis lyase pdxS; TIGRFAM: pyridoxine biosynthesis protein; PFAM: SOR/SNZ family; TIGRFAM: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 YP_004099101.1 InterPro IPR016160; KEGG: kra:Krad_3061 hypothetical protein; SPTR: secreted protein YP_004099102.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: xce:Xcel_1660 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; PRIAM: phosphatidylinositol alpha-mannosyltransferase; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004099103.1 COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: kra:Krad_3063 lipid A biosynthesis lauroyl acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: lipid A biosynthesis lauroyl acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase YP_004099104.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: kfl:Kfla_3366 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_004099105.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: kra:Krad_3065 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: HIT family protein; PFAM: HIT domain YP_004099106.1 COGs: COG3303 formate-dependent nitrite reductase periplasmic cytochrome C552 subunit; InterPro IPR003321: IPR011031; KEGG: ahe:Arch_1474 nitrite reductase (cytochrome; ammonia-forming); PFAM: cytochrome C552; PRIAM: nitrite reductase (cytochrome; ammonia-forming); SPTR: nitrite reductase (cytochrome; ammonia-forming); PFAM: cytochrome C552 YP_004099107.1 COGs: COG3005 nitrate/TMAO reductase membrane-bound tetraheme cytochrome C subunit; InterPro IPR017571: IPR011031; KEGG: ahe:Arch_1475 cytochrome C nitrate reductase, small subunit; SPTR: cytochrome c nitrate reductase, small subunit; TIGRFAM: cytochrome C nitrate reductase, small subunit; PFAM: NapC/NirT cytochrome C family, N-terminal region; TIGRFAM: cytochrome C nitrate reductase, small subunit YP_004099108.1 InterPro IPR000551; KEGG: tro:trd_1180 transcriptional regulator, MerR family protein; PFAM: regulatory protein MerR; SPTR: MerR family transcriptional regulator protein; PFAM: MerR family regulatory protein; TIGRFAM: DNA binding domain, excisionase family YP_004099109.1 InterPro IPR005126: IPR011031; KEGG: gem:GM21_1063 hypothetical protein; PFAM: NapC/NirT cytochrome C domain protein; SPTR: uncharacterized protein; PFAM: NapC/NirT cytochrome C family, N-terminal region YP_004099110.1 COGs: COG1225 peroxiredoxin; InterPro IPR000866: IPR017936; KEGG: ahe:Arch_1469 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family YP_004099111.1 COGs: COG0755 ABC-type transporter involved in cytochrome C biogenesis permease; InterPro IPR002541: IPR017562; KEGG: ahe:Arch_1470 cytochrome C biogenesis protein CcsB; PFAM: cytochrome C assembly protein; SPTR: cytochrome C biogenesis protein CcsB; TIGRFAM: cytochrome C biogenesis protein CcsB; PFAM: cytochrome C assembly protein; TIGRFAM: cytochrome C biogenesis protein CcsB YP_004099112.1 COGs: COG1333 ResB protein required for cytochrome C biosynthesis; KEGG: ahe:Arch_1471 ResB family protein; SPTR: ResB family protein; PFAM: ResB-like family YP_004099113.1 COGs: COG0785 cytochrome C biogenesis protein; InterPro IPR003834; KEGG: ahe:Arch_1472 cytochrome C biogenesis protein transmembrane region; PFAM: cytochrome C biogenesis protein transmembrane region; SPTR: cytochrome C biogenesis protein transmembrane region; PFAM: cytochrome C biogenesis protein transmembrane region YP_004099114.1 InterPro IPR019734: IPR013026; KEGG: ahe:Arch_1473 tetratricopeptide TPR_2 repeat protein; SMART: hypothetical protein; SPTR: hypothetical protein YP_004099115.1 InterPro IPR010177: IPR011031; KEGG: rfr:Rfer_0259 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: cytochrome C family protein; PFAM: Doubled CXXCH motif (Paired_CXXCH_1); TIGRFAM: doubled CXXCH domain YP_004099116.1 InterPro IPR010177: IPR011031; KEGG: tjr:TherJR_1122 cytochrome C family protein; SPTR: cytochrome C family protein; TIGRFAM: cytochrome C family protein; PFAM: Doubled CXXCH motif (Paired_CXXCH_1); TIGRFAM: doubled CXXCH domain YP_004099117.1 COGs: COG3391 conserved hypothetical protein; InterPro IPR001258: IPR013017; KEGG: chy:CHY_0222 NHL repeat-containing protein; PFAM: NHL repeat containing protein; SPTR: NHL repeat protein; PFAM: NHL repeat YP_004099118.1 InterPro IPR001440: IPR019734: IPR013026; KEGG: cyp:PCC8801_1300 hypothetical protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: hypothetical protein; SPTR: TPR repeat-containing protein; PFAM: hypothetical protein YP_004099119.1 COGs: COG3850 Signal transduction histidine kinase nitrate/nitrite-specific; InterPro IPR011712: IPR003594: IPR005467; KEGG: ttr:Tter_2549 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004099120.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: tbi:Tbis_0775 LuxR family two component transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004099121.1 InterPro IPR001261; KEGG: psl:Psta_4748 two component LuxR family transcriptional regulator; SPTR: Two-component system regulatory protein YP_004099122.1 KEGG: cmi:CMM_1972 hypothetical protein; SPTR: Hypothetical membrane protein YP_004099123.1 COGs: COG0441 threonyl-tRNA synthetase; InterProIPR018158: IPR012947: IPR002314: IPR004154: IPR 002320: IPR006195; KEGG: kse:Ksed_15440 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); threonyl/alanyl tRNA synthetase SAD; anticodon-binding domain protein; SPTR: threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: anticodon binding domain; threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase YP_004099124.1 InterPro IPR000182; KEGG: kfl:Kfla_3200 GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase YP_004099125.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR014187; KEGG: sro:Sros_4103 alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase; TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: alcohol dehydrogenase GroES-like domain; TIGRFAM: zinc-binding alcohol dehydrogenase family protein YP_004099126.1 InterPro IPR002539; KEGG: gob:Gobs_0308 MaoC domain protein dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: dehydratase; PFAM: MaoC like domain YP_004099127.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904; KEGG: gob:Gobs_0307 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004099128.1 COGs: COG0183 acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155; KEGG: cwo:Cwoe_0195 acetyl-CoA acetyltransferase; PFAM: thiolase-like; PRIAM: acetyl-CoA C-acyltransferase; SPTR: acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase, C-terminal domain; thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_004099129.1 InterPro IPR001647; KEGG: kra:Krad_4029 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: TetR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004099130.1 InterPro IPR002563; KEGG: nca:Noca_3103 flavin reductase domain-containing protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavin reductase domain protein, FMN-binding; PFAM: Flavin reductase like domain YP_004099131.1 InterPro IPR010916; KEGG: gob:Gobs_3189 MOSC domain protein beta barrel domain protein; SPTR: MOSC domain protein beta barrel domain protein YP_004099132.1 InterPro IPR013434; KEGG: kfl:Kfla_3574 hypothetical protein; SPTR: uncharacterized protein; PFAM: transmembrane protein (PGPGW); TIGRFAM: conserved hypothetical protein TIGR02611 YP_004099133.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544: IPR018300; KEGG: sma:SAV_6804 D-alanine aminotransferase; PFAM: aminotransferase class IV; SPTR: D-alanine aminotransferase; PFAM: Aminotransferase class IV YP_004099134.1 COGs: COG0147 anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999: IPR015890; KEGG: sco:SCO1547 anthranilate synthase; PFAM: chorismate binding-like; SPTR: Aminodeoxychorismate synthase; PFAM: chorismate binding enzyme YP_004099135.1 COGs: COG0386 glutathione peroxidase; InterPro IPR000889; KEGG: kse:Ksed_02770 glutathione peroxidase; PFAM: glutathione peroxidase; PRIAM: peroxiredoxin; SPTR: glutathione peroxidase; PFAM: glutathione peroxidase YP_004099136.1 COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755: IPR014145; KEGG: amd:AMED_4612 ATP-dependent DNA ligase; PFAM: DNA primase small subunit; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: Eukaryotic and archaeal DNA primase small subunit; TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain YP_004099137.1 KEGG: mmu:232714 maltase-glucoamylase; SPTR: membrane-bound maltase-glucoamylase YP_004099138.1 COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: kfl:Kfla_3332 ribonuclease BN; PFAM: ribonuclease BN; SPTR: integral membrane protein; PFAM: ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_004099139.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006091: IPR006090: IPR006089; KEGG: sma:SAV_2123 acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain YP_004099140.1 COGs: COG2326 conserved hypothetical protein; InterPro IPR005660: IPR016898; KEGG: kse:Ksed_15560 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Uncharacterized conserved protein; PFAM: polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:nucleotide phosphotransferase, PPK2 family YP_004099141.1 COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR002734; KEGG: nca:Noca_4154 hypothetical protein; PFAM: bifunctional deaminase-reductase domain protein; SPTR: Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain YP_004099142.1 KEGG: kra:Krad_1592 secreted protein; SPTR: Secreted protein YP_004099143.1 COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: kfl:Kfla_3725 methionine-R-sulfoxide reductase; PFAM: methionine sulfoxide reductase B; PRIAM: peptide-methionine (R)-S-oxide reductase; SPTR: methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase YP_004099144.1 COGs: COG3253 conserved hypothetical protein; InterPro IPR010644; KEGG: kfl:Kfla_3727 chlorite dismutase; PFAM: chlorite dismutase; SPTR: uncharacterized protein; PFAM: chlorite dismutase YP_004099145.1 COGs: COG1232 protoporphyrinogen oxidase; InterPro IPR002937: IPR004572; KEGG: cai:Caci_6784 protoporphyrinogen oxidase; PFAM: amine oxidase; PRIAM: protoporphyrinogen oxidase; SPTR: protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: protoporphyrinogen oxidase YP_004099146.1 KEGG: sgr:SGR_1471 hypothetical protein; SPTR: lipoprotein YP_004099147.1 COGs: COG0728 membrane protein virulence factor; InterPro IPR004268; KEGG: kse:Ksed_26920 integral membrane protein MviN; PFAM: virulence factor MVIN family protein; SPTR: integral membrane protein MviN; TIGRFAM: integral membrane protein MviN; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN YP_004099148.1 COGs: COG0407 uroporphyrinogen-III decarboxylase; InterPro IPR000257: IPR006361; KEGG: stp:Strop_1532 uroporphyrinogen decarboxylase; PFAM: uroporphyrinogen decarboxylase (URO-D); PRIAM: uroporphyrinogen decarboxylase; SPTR: uroporphyrinogen decarboxylase; TIGRFAM: uroporphyrinogen decarboxylase; manually curated; PFAM: uroporphyrinogen decarboxylase (URO-D); TIGRFAM: uroporphyrinogen decarboxylase YP_004099149.1 KEGG: bcv:Bcav_1965 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3000) YP_004099150.1 COGs: COG0349 ribonuclease D; InterPro IPR002562: IPR002121: IPR018312; KEGG: sma:SAV_2231 ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein; SPTR: ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain; TIGRFAM: ribonuclease D YP_004099151.1 COGs: COG0183 acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155: IPR020613; KEGG: cai:Caci_6777 acetyl-CoA acetyltransferase; PFAM: thiolase-like; PRIAM: acetyl-CoA C-acyltransferase; SPTR: acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase, C-terminal domain; thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_004099152.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753: IPR006176: IPR006108; KEGG: tcu:Tcur_1759 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004099153.1 COGs: COG0702 nucleoside-diphosphate-sugar epimerase; KEGG: rha:RHA1_ro08384 nucleoside diphosphate sugar epimerase; SPTR: Possible nucleoside diphosphate sugar epimerase; PFAM: NmrA-like family YP_004099154.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR001387: IPR001986; KEGG: scb:SCAB_21131 UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Helix-turn-helix; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004099155.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR011294: IPR020904; KEGG: kfl:Kfla_5322 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-hydroxybutyrate dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short chain dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase YP_004099156.1 COGs: COG2508 Regulator of polyketide synthase expression; InterPro IPR003018; KEGG: kfl:Kfla_5320 phytochrome sensor protein; PFAM: GAF domain protein; SMART: GAF domain protein; SPTR: GAF domain protein; PFAM: GAF domain YP_004099157.1 InterPro IPR000073; KEGG: gob:Gobs_4995 alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: alpha/beta hydrolase superfamily protein-like; PFAM: alpha/beta hydrolase fold YP_004099158.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: nml:Namu_3914 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004099159.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: nml:Namu_3913 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004099160.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: nml:Namu_3912 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004099161.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: nml:Namu_3911 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004099162.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR000709: IPR001828; KEGG: cai:Caci_7912 extracellular ligand-binding receptor; PFAM: extracellular ligand-binding receptor; SPTR: extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004099163.1 COGs: COG1154 deoxyxylulose-5-phosphate synthase; InterProIPR005475: IPR005476: IPR005477: IPR005474: IPR 020826; KEGG: cfl:Cfla_1720 deoxyxylulose-5-phosphate synthase; PFAM: transketolase central region; transketolase domain-containing protein; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004099164.1 KEGG: kse:Ksed_15730 hypothetical protein; SPTR: uncharacterized protein YP_004099165.1 COGs: COG1048 Aconitase A; InterPro IPR001030: IPR000573: IPR006249: IPR018136; KEGG: xce:Xcel_1909 aconitate hydratase 1; PFAM: aconitate hydratase domain-containing protein; SPTR: Aconitate hydratase; TIGRFAM: aconitate hydratase 1; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1 YP_004099166.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792; KEGG: kra:Krad_1564 deoxyribonuclease/rho motif-related TRAM; PFAM: deoxyribonuclease/rho motif-related TRAM; SPTR: RNA methyltransferase; PFAM: tRNA (uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA YP_004099167.1 COGs: COG0531 Amino acid transporter; KEGG: cfl:Cfla_1709 hypothetical protein; SPTR: Probable membrane protein; TC 2.A.3 YP_004099168.1 COGs: COG0569 K+ transporters NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: kfl:Kfla_3761 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein; manually curated; PFAM: TrkA-N domain; TrkA-C domain YP_004099169.1 COGs: COG0569 K+ transporters NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: ske:Sked_16160 K+ transporter NAD-binding component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain YP_004099170.1 KEGG: kse:Ksed_15770 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3159) YP_004099171.1 KEGG: tcu:Tcur_1708 nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Nucleic acid binding OB-fold tRNA/helicase-type YP_004099172.1 KEGG: kra:Krad_1558 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3710) YP_004099173.1 COGs: COG0756 dUTPase; InterPro IPR008180: IPR008181; KEGG: ace:Acel_1402 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; PRIAM: dUTP diphosphatase; SPTR: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) YP_004099174.1 KEGG: bcv:Bcav_1935 hypothetical protein; SPTR: uncharacterized protein YP_004099175.1 KEGG: tbi:Tbis_2706 hypothetical protein; SPTR: uncharacterized protein YP_004099176.1 COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760: IPR020583: IPR020550; KEGG: cfl:Cfla_1700 inositol monophosphatase; PFAM: inositol monophosphatase; SPTR: myo-inositol 1-monophosphatase; PFAM: inositol monophosphatase family YP_004099177.1 COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015; KEGG: kse:Ksed_15820 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase YP_004099178.1 COGs: COG2860 membrane protein; InterPro IPR005115; KEGG: kse:Ksed_15830 predicted membrane protein; PFAM: Uncharacterised protein family UPF0126; SPTR: Predicted membrane protein; PFAM: UPF0126 domain YP_004099179.1 KEGG: kra:Krad_1551 DNA-binding protein; SPTR: DNA-binding protein; PFAM: protein of unknown function (DUF3071) YP_004099180.1 COGs: COG1435 thymidine kinase; InterPro IPR001267: IPR020634; KEGG: kse:Ksed_15850 thymidine kinase; PFAM: thymidine kinase; PRIAM: thymidine kinase; SPTR: thymidine kinase; PFAM: thymidine kinase YP_004099181.1 COGs: COG1524 Uncharacterized protein of the AP superfamily; InterPro IPR002591; KEGG: kra:Krad_1550 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: uncharacterized protein; PFAM: type I phosphodiesterase / nucleotide pyrophosphatase YP_004099182.1 KEGG: kse:Ksed_15870 hypothetical protein; SPTR: uncharacterized protein YP_004099183.1 COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR000182: IPR003781; KEGG: kra:Krad_1548 CoA-binding protein; PFAM: CoA-binding protein; GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: CoA binding domain; acetyltransferase (GNAT) family YP_004099184.1 COGs: COG0778 nitroreductase; InterPro IPR000415; KEGG: gob:Gobs_3234 nitroreductase; PFAM: nitroreductase; SPTR: nitroreductase; PFAM: nitroreductase family YP_004099185.1 COGs: COG0188 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) subunit alpha; InterPro IPR002205: IPR006691; KEGG: kfl:Kfla_3453 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: DNA gyrase subunit A; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller YP_004099186.1 COGs: COG4759 Uncharacterized protein containing thioredoxin-like domain; InterPro IPR009737; KEGG: sen:SACE_1358 hypothetical protein; PFAM: Sucraseferredoxin family protein; SPTR: uncharacterized protein; PFAM: Sucrase/ferredoxin-like YP_004099187.1 COGs: COG0187 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR001241: IPR000565: IPR003594: IPR013506: IPR 006171: IPR002288: IPR018522; KEGG: ach:Achl_1613 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIsubunit alpha B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: DNA gyrase subunit B; PFAM: Toprim domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus YP_004099188.1 KEGG: sro:Sros_7085 hypothetical protein; SPTR: uncharacterized protein YP_004099189.1 InterPro IPR007403; KEGG: mjl:Mjls_0085 hypothetical protein; PFAM: protein of unknown function DUF456; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF456) YP_004099190.1 KEGG: kra:Krad_3212 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3040) YP_004099191.1 COGs: COG0389 nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR001126: IPR017963; KEGG: kra:Krad_3213 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: DNA-directed DNA polymerase; PFAM: impB/mucB/samB family C-terminal; impB/mucB/samB family; IMS family HHH motif YP_004099192.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013217; KEGG: tcu:Tcur_2941 methyltransferase type 11; PFAM: methyltransferase type 12; SPTR: methyltransferase; PFAM: methyltransferase domain YP_004099193.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013: IPR011708: IPR004365: IPR003141: IPR 004805; KEGG: kra:Krad_3215 DNA polymerase III subunit alpha; PFAM: DNA polymerase III subunit alpha; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III subunit alpha; TIGRFAM: DNA polymerase III subunit alpha; PFAM: PHP domain; Bacterial DNA polymerase III subunit alpha; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004099194.1 KEGG: kse:Ksed_16050 hypothetical protein; SPTR: uncharacterized protein YP_004099195.1 KEGG: kra:Krad_3217 hypothetical protein; SPTR: uncharacterized protein YP_004099196.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: tcu:Tcur_3021 YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK / prolyl-tRNA synthetases associated domain YP_004099197.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171: IPR004620; KEGG: kfl:Kfla_2858 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; PRIAM: methylenetetrahydrofolate reductase (NAD(P)H); SPTR: methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form YP_004099198.1 COGs: COG0142 geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: kra:Krad_3227 polyprenyl synthetase; PFAM: polyprenyl synthetase; SPTR: polyprenyl synthase / dimethylallyltranstransferase; PFAM: polyprenyl synthetase YP_004099199.1 KEGG: kra:Krad_3230 hypothetical protein; SPTR: transcriptional regulatory protein; TIGRFAM: DNA binding domain, excisionase family YP_004099200.1 InterPro IPR018392: IPR008258: IPR002482; KEGG: ach:Achl_1556 lytic transglycosylase catalytic; PFAM: lytic transglycosylase catalytic; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: lytic transglycosylase catalytic; PFAM: transglycosylase SLT domain; LysM domain YP_004099201.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR020635: IPR002290: IPR 008271: IPR000719; KEGG: nca:Noca_3086 protein kinase; PFAM: serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: serine/threonine kinase; PFAM: protein kinase domain; PASTA domain YP_004099202.1 COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620; KEGG: nca:Noca_3091 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004099203.1 COGs: COG2008 threonine aldolase; InterPro IPR001597; KEGG: nca:Noca_3094 L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: threonine aldolase; SPTR: L-allo-threonine aldolase; PFAM: beta-eliminating lyase YP_004099204.1 COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: kra:Krad_3233 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II YP_004099205.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sgr:SGR_5383 two-component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004099206.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: cai:Caci_6058 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004099207.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: fre:Franean1_1829 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: uncharacterized protein; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004099208.1 InterPro IPR002202; KEGG: scb:SCAB_67571 hypothetical protein; SPTR: uncharacterized protein YP_004099209.1 COGs: COG3568 metal-dependent hydrolase; InterPro IPR005135; KEGG: tfu:Tfu_1034 hypothetical protein; PFAM: endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: endonuclease/exonuclease/phosphatase family YP_004099210.1 COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600: IPR004654; KEGG: sco:SCO6260 sugar kinase; PFAM: ROK family protein; SPTR: sugar kinase; TIGRFAM: glucokinase, ROK family; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004099211.1 KEGG: gob:Gobs_3327 hypothetical protein; SPTR: uncharacterized protein YP_004099212.1 InterPro IPR005031; KEGG: amd:AMED_2448 cyclase/dehydrase; PFAM: cyclase/dehydrase; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport YP_004099213.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: bcv:Bcav_1901 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: long chain fatty acid CoA ligase; PFAM: AMP-binding enzyme YP_004099214.1 KEGG: kfl:Kfla_2801 hypothetical protein; SPTR: uncharacterized protein YP_004099215.1 KEGG: fre:Franean1_1818 hypothetical protein; SPTR: uncharacterized protein YP_004099216.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; InterPro IPR013520: IPR000305: IPR006055: IPR006054; KEGG: kra:Krad_3247 hypothetical protein; PFAM: exonuclease RNase T and DNA polymerase III; excinuclease ABC subunit C PRIAM: DNA-directed DNA polymerase; SMART: exonuclease; excinuclease ABC subunit C SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III subunit epsilon; PFAM: exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III subunit epsilon family YP_004099217.1 InterPro IPR019887; KEGG: bcv:Bcav_1895 transcriptional regulator, AsnC family; PFAM: transcription regulator AsnC-type-like; SPTR: transcriptional regulator; PFAM: AsnC family YP_004099218.1 COGs: COG0547 anthranilate phosphoribosyltransferase; InterPro IPR017459: IPR000312: IPR005940; KEGG: nca:Noca_3131 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; glycosyl transferase, family 3-like; PRIAM: anthranilate phosphoribosyltransferase; SPTR: anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family, a/b domain; glycosyl transferase family, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_004099219.1 InterPro IPR001789; KEGG: bcv:Bcav_1893 response regulator receiver protein; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain YP_004099220.1 COGs: COG1845 Heme/copper-type cytochrome/quinol oxidase subunit 3; InterPro IPR000298; KEGG: kse:Ksed_16180 heme/copper-type cytochrome/quinol oxidase subunit 3; PFAM: cytochrome C oxidase subunit III; PRIAM: cytochrome-c oxidase; SPTR: Heme/copper-type cytochrome/quinol oxidase subunit 3; manually curated; PFAM: cytochrome C oxidase subunit III YP_004099221.1 InterPro IPR003088: IPR009152: IPR009056; KEGG: kse:Ksed_16190 cytochrome C, mono- and diheme variants family; PFAM: cytochrome C class I; SPTR: cytochrome C heme-binding subunit; PFAM: cytochrome C YP_004099222.1 COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941; KEGG: kse:Ksed_16200 Rieske Fe-S protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske iron-sulphur component of ubiQ-cytB reductase; PFAM: Rieske [2Fe-2S] domain YP_004099223.1 COGs: COG1290 cytochrome b subunit of the bc complex; InterPro IPR005797; KEGG: kse:Ksed_16210 cytochrome b subunit of the bc complex; PFAM: cytochrome b/b6 domain; SPTR: cytochrome B subunit; PFAM: cytochrome b(N-terminal)/b6/petB YP_004099224.1 COGs: COG3824 conserved hypothetical protein; InterPro IPR010428; KEGG: bcv:Bcav_3505 protein of unknown function DUF1025; PFAM: protein of unknown function DUF1025; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1025) YP_004099225.1 KEGG: kse:Ksed_16230 hypothetical protein; SPTR: uncharacterized protein; PFAM: cytochrome C oxidase subunit IV YP_004099226.1 COGs: COG0843 Heme/copper-type cytochrome/quinol oxidase subunit 1; InterPro IPR000883: IPR014241; KEGG: xce:Xcel_2015 cytochrome C oxidase subunit I; PFAM: cytochrome C oxidase subunit I; SPTR: cytochrome C oxidase subunit I; TIGRFAM: cytochrome C oxidase subunit I; PFAM: cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome C oxidase subunit I YP_004099227.1 COGs: COG1622 Heme/copper-type cytochrome/quinol oxidase subunit 2; InterPro IPR002429: IPR014222: IPR001505; KEGG: cfl:Cfla_2082 cytochrome C oxidase subunit II; PFAM: cytochrome C oxidase subunit II; SPTR: cytochrome C oxidase subunit 2; TIGRFAM: cytochrome C oxidase subunit II; PFAM: cytochrome C oxidase subunit II, periplasmic domain; TIGRFAM: cytochrome C oxidase subunit II YP_004099228.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: stp:Strop_3301 aminotransferase, class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: aminotransferase; PFAM: Aminotransferase class-V YP_004099229.1 InterPro IPR001455; KEGG: scb:SCAB_67281 pyridoxalphosphate dependent protein; PFAM: SirA-like domain-containing protein; SPTR: SirA family protein; PFAM: SirA-like protein YP_004099230.1 COGs: COG2360 Leu/Phe-tRNA-protein transferase; InterPro IPR004616; KEGG: kra:Krad_3260 leucyl/phenylalanyl-tRNA--protein transferase; PFAM: leucyl/phenylalanyl-tRNA--protein transferase; PRIAM: leucyltransferase; SPTR: leucyl/phenylalanyl-tRNA--protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA/protein transferase; PFAM: leucyl/phenylalanyl-tRNA protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA--protein transferase YP_004099231.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: tbi:Tbis_1286 PfkB domain-containing protein; PFAM: PfkB domain protein; SPTR: carbohydrate kinase; PFAM: pfkB family carbohydrate kinase YP_004099232.1 COGs: COG2345 transcriptional regulator protein; KEGG: nca:Noca_4305 transcriptional regulator; SPTR: transcriptional regulator YP_004099233.1 KEGG: nca:Noca_4304 hypothetical protein; SPTR: uncharacterized protein; PFAM: DSBA-like thioredoxin domain YP_004099234.1 InterPro IPR000813: IPR017900: IPR017896; KEGG: msm:MSMEG_1124 ferredoxin FdxA; SPTR: ferredoxin FdxA; PFAM: 4Fe-4S binding domain YP_004099235.1 KEGG: nda:Ndas_0039 ABC transporter; SPTR: ABC transporter YP_004099236.1 COGs: COG0316 conserved hypothetical protein; InterPro IPR000361: IPR016092: IPR017870; KEGG: kra:Krad_3261 iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: uncharacterized protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein YP_004099237.1 COGs: COG1929 glycerate kinase; InterPro IPR004381; KEGG: tfu:Tfu_1010 glycerate kinase; PFAM: glycerate kinase; PRIAM: glycerate kinase; SPTR: glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase family; TIGRFAM: glycerate kinase YP_004099238.1 COGs: COG0379 Quinolinate synthase; InterPro IPR003473; KEGG: nca:Noca_3149 quinolinate synthetase; PFAM: Quinolinate synthetase A; PRIAM: Quinolinate synthase; SPTR: Quinolinate synthetase; TIGRFAM: quinolinate synthetase complex, subunit alpha; PFAM: Quinolinate synthetase A protein; TIGRFAM: quinolinate synthetase complex, subunit alpha YP_004099239.1 InterPro IPR011152; KEGG: cfl:Cfla_2021 metallophosphoesterase; SPTR: metallophosphoesterase YP_004099240.1 COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933: IPR011650; KEGG: kse:Ksed_16280 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: uncharacterized protein; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain YP_004099241.1 COGs: COG2518 protein-L-isoaspartate carboxylmethyltransferase; InterPro IPR000682; KEGG: nca:Noca_4541 protein-L-isoaspartate(D-aspartate) O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; PRIAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; SPTR: protein-L-isoaspartate(D-aspartate) O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_004099242.1 KEGG: bcv:Bcav_1880 integral membrane protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3043) YP_004099243.1 COGs: COG1680 beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: kfl:Kfla_6857 beta-lactamase; PFAM: beta-lactamase; SPTR: beta-lactamase; PFAM: beta-lactamase YP_004099244.1 KEGG: ace:Acel_0947 hypothetical protein; SPTR: uncharacterized protein YP_004099245.1 KEGG: kfl:Kfla_2711 hypothetical protein; SPTR: uncharacterized protein YP_004099246.1 InterPro IPR003339; KEGG: sco:SCO2323 integral membrane protein; PFAM: cobalt transporter; SPTR: Cobalt transporter; PFAM: Cobalt transporter YP_004099247.1 COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterPro IPR003439: IPR003593: IPR017871; KEGG: kfl:Kfla_2709 ABC transporter; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004099248.1 InterPro IPR017196; KEGG: stp:Strop_4401 hypothetical protein; SPTR: integral membrane protein; PFAM: protein of unknown function (DUF1393) YP_004099249.1 COGs: COG2087 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: amd:AMED_7046 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; SPTR: adenosylcobinamide kinase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase YP_004099250.1 COGs: COG0368 Cobalamin-5-phosphate synthase; InterPro IPR003805; KEGG: nml:Namu_0166 cobalamin-5-phosphate synthase CobS; PFAM: cobalamin-5-phosphate synthase CobS; SPTR: Cobalamin-5-phosphate synthase cobS; PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase YP_004099251.1 COGs: COG0404 glycine cleavage system protein T (aminomethyltransferase); InterPro IPR006222: IPR013977: IPR006223; KEGG: fra:Francci3_3132 glycine cleavage system aminomethyltransferase T; PFAM: glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; SPTR: Aminomethyltransferase; TIGRFAM: glycine cleavage system T protein; PFAM: Aminomethyltransferase folate-binding domain; glycine cleavage T-protein C-terminal barrel domain; TIGRFAM: glycine cleavage system T protein YP_004099252.1 COGs: COG0260 leucyl aminopeptidase; InterPro IPR000819: IPR008283; KEGG: ske:Sked_15490 leucyl aminopeptidase; PFAM: peptidase M17 leucyl aminopeptidase domain protein; SPTR: leucyl aminopeptidase; PFAM: Cytosol aminopeptidase family, catalytic domain; Cytosol aminopeptidase family, N-terminal domain YP_004099253.1 KEGG: amd:AMED_6959 hypothetical protein; SPTR: uncharacterized protein YP_004099254.1 KEGG: cfl:Cfla_2099 hypothetical protein; SPTR: uncharacterized protein YP_004099255.1 COGs: COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR000815: IPR004099: IPR006258: IPR 012999; KEGG: kra:Krad_3278 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase YP_004099256.1 COGs: COG0508 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR000089: IPR004167: IPR001078: IPR014276: IPR 003016; KEGG: bcv:Bcav_1862 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase YP_004099257.1 COGs: COG1090 nucleoside-diphosphate sugar epimerase; InterPro IPR001509: IPR013549: IPR010099; KEGG: bcv:Bcav_1861 domain of unknown function DUF1731; PFAM: hypothetical protein; NAD-dependent epimerase/dehydratase; SPTR: NAD dependent epimerase/dehydratase family protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777 YP_004099258.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR017442: IPR020635: IPR002290: IPR017441: IPR 020929: IPR000719; KEGG: gob:Gobs_3363 serine/threonine protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Probable serine/threonine-protein kinase transcriptional regulatoryprotein pknk (protein kinase k) (Stpk k); PFAM: protein kinase domain YP_004099259.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: ske:Sked_15440 predicted dehydrogenase; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: oxidoreductase; PFAM: oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase family, C-terminal alpha/beta domain YP_004099260.1 COGs: COG0321 Lipoate-protein ligase B; InterPro IPR004143: IPR000544: IPR020605; KEGG: sro:Sros_2641 lipoyl(octanoyl) transferase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Lipoyl(octanoyl) transferase; SPTR: Octanoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B YP_004099261.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: kfl:Kfla_1062 ABC transporter related protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004099262.1 KEGG: ske:Sked_02620 hypothetical protein; SPTR: uncharacterized protein YP_004099263.1 COGs: COG0320 Lipoate synthase; InterPro IPR007197: IPR006638: IPR003698; KEGG: kse:Ksed_16380 lipoyl synthase; PFAM: radical SAM domain protein; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoyl synthase; TIGRFAM: lipoic acid synthetase; PFAM: radical SAM superfamily; TIGRFAM: lipoate synthase YP_004099264.1 KEGG: kra:Krad_3289 integral membrane protein; SPTR: integral membrane protein YP_004099265.1 InterPro IPR010432: IPR016795; KEGG: aau:AAur_1745 transRDD family protein; PFAM: RDD domain containing protein; SPTR: transmembrane protein, RDD family domain; PFAM: RDD family YP_004099266.1 COGs: COG0174 glutamine synthetase; InterPro IPR008147: IPR008146: IPR004809; KEGG: kra:Krad_3291 glutamine synthetase; PFAM: glutamine synthetase; glutamine synthetase beta-Grasp; SPTR: glutamine synthetase; TIGRFAM: glutamine synthetase; PFAM: glutamine synthetase, catalytic domain; glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase YP_004099267.1 InterPro IPR002362; KEGG: kfl:Kfla_6334 hypothetical protein; SPTR: uncharacterized protein YP_004099268.1 InterPro IPR011701; KEGG: gob:Gobs_1534 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004099269.1 COGs: COG1391 glutamine synthetase adenylyltransferase; InterPro IPR005190: IPR013546; KEGG: kra:Krad_3295 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; PFAM: glutamate-ammonia ligase adenylyltransferase; GlnD PII-uridylyltransferase; PRIAM: [glutamate--ammonia-ligase] adenylyltransferase; SPTR: glutamate-ammonia-ligase adenylyltransferase; PFAM: GlnD PII-uridylyltransferase; glutamate-ammonia ligase adenylyltransferase YP_004099270.1 COGs: COG0174 glutamine synthetase; InterPro IPR008147: IPR008146; KEGG: tbi:Tbis_1258 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; PRIAM: glutamate--ammonia ligase; SPTR: glutamine synthetase type I; PFAM: glutamine synthetase, catalytic domain; glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase YP_004099271.1 COGs: COG4412 conserved hypothetical protein; InterPro IPR008757: IPR012300: IPR017683; KEGG: rxy:Rxyl_1277 peptidase M6, immune inhibitor A; PFAM: peptidase M6 immune inhibitor A; SPTR: secreted protease; TIGRFAM: M6 family metalloprotease domain protein; PFAM: Immune inhibitor A peptidase M6; TIGRFAM: M6 family metalloprotease domain YP_004099272.1 COGs: COG0413 Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: amd:AMED_1209 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_004099273.1 KEGG: kse:Ksed_12170 hypothetical protein; SPTR: methionine aminopeptidase YP_004099274.1 COGs: COG0024 methionine aminopeptidase; InterPro IPR001714: IPR000994: IPR002467; KEGG: kse:Ksed_12160 methionine aminopeptidase, type I; PFAM: peptidase M24; SPTR: methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; manually curated; PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_004099275.1 COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: kse:Ksed_12150 polyphosphate glucokinase; PFAM: ROK family protein; SPTR: polyphosphate glucokinase/transcriptional regulator; PFAM: ROK family YP_004099276.1 KEGG: xce:Xcel_0944 hypothetical protein; SPTR: uncharacterized protein YP_004099277.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR003593; KEGG: cfl:Cfla_0974 ABC transporter related protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004099278.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: kra:Krad_4081 Zn-dependent hydrolase; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily YP_004099279.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR001958: IPR011701: IPR005829: IPR000740; KEGG: kse:Ksed_04650 arabinose efflux permease family protein; PFAM: major facilitator superfamily MFS_1; SPTR: multidrug resistance protein; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily YP_004099280.1 COGs: COG3573 oxidoreductase; InterPro IPR003953: IPR014614; KEGG: rce:RC1_0236 hypothetical protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: uncharacterized protein; PFAM: FAD binding domain YP_004099281.1 COGs: COG0028 thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR011766; KEGG: maq:Maqu_2345 hypothetical protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: thiamine pyrophosphate protein domain protein TPP-binding; PFAM: thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004099282.1 KEGG: amd:AMED_8580 hypothetical protein; SPTR: uncharacterized protein YP_004099283.1 COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: kse:Ksed_12120 exoribonuclease R; PFAM: ribonuclease II; SPTR: ribonuclease R; PFAM: RNB domain YP_004099284.1 COGs: COG3022 conserved hypothetical protein; InterPro IPR005583; KEGG: kfl:Kfla_3501 protein of unknown function DUF328; PFAM: protein of unknown function DUF328; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF328) YP_004099285.1 COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277: IPR006234; KEGG: nfa:nfa53590 O-succinylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: cystathionine gamma-synthase; SPTR: O-succinylhomoserine sulfhydrylase; TIGRFAM: O-succinylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine sulfhydrylase YP_004099286.1 InterPro IPR001763; KEGG: cfl:Cfla_2946 rhodanese domain protein; SMART: rhodanese; SPTR: uncharacterized protein; PFAM: Rhodanese-like domain YP_004099287.1 COGs: COG0328 ribonuclease HI; InterPro IPR002156; KEGG: gob:Gobs_3460 phosphoglycerate mutase; PFAM: ribonuclease H; SPTR: Bifunctional RNase H/acid phosphatase; PFAM: RNase H YP_004099288.1 COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: tcu:Tcur_1674 protein of unknown function DUF164; PFAM: protein of unknown function DUF164; SPTR: Zn-ribbon protein-like protein; manually curated; PFAM: zinc ribbon domain YP_004099289.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: xce:Xcel_2085 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family YP_004099290.1 COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262: IPR012133: IPR008259; KEGG: sen:SACE_5887 L-lactate dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; PRIAM: (S)-2-hydroxy-acid oxidase; SPTR: L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase YP_004099291.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR000709: IPR001828; KEGG: gob:Gobs_1651 extracellular ligand-binding receptor; PFAM: extracellular ligand-binding receptor; SPTR: extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004099292.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: gob:Gobs_1652 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004099293.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR001851: IPR003439: IPR003593: IPR017871; KEGG: gob:Gobs_1653 ABC transporter; PFAM: ABC transporter; inner-membrane translocator; SMART: ATPase AAA; SPTR: ABC transporter protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; Branched-chain amino acid transporter / permease YP_004099294.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: gob:Gobs_1654 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004099295.1 COGs: COG1225 peroxiredoxin; InterPro IPR000866: IPR017936; KEGG: sen:SACE_1534 AhpC/TSA family protein; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; SPTR: thiol-specific antioxidant protein; PFAM: AhpC/TSA family YP_004099296.1 KEGG: kra:Krad_3338 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3052) YP_004099297.1 COGs: COG2609 pyruvate dehydrogenase complex dehydrogenase (E1) component; InterPro IPR004660; KEGG: kra:Krad_3340 pyruvate dehydrogenase subunit E1; SPTR: pyruvate dehydrogenase E1 component; TIGRFAM: 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; PFAM: transketolase, thiamine diphosphate binding domain; TIGRFAM: pyruvate dehydrogenase E1 component, homodimeric type YP_004099298.1 COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518: IPR018223; KEGG: nca:Noca_2474 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; manually curated; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase YP_004099299.1 COGs: COG2508 Regulator of polyketide synthase expression; KEGG: sco:SCO2386 hypothetical protein; SPTR: uncharacterized protein YP_004099300.1 COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043; KEGG: ach:Achl_2205 (acyl-carrier-protein) S-malonyltransferase; PFAM: acyl transferase; PRIAM: [acyl-carrier-protein] S-malonyltransferase; SPTR: acyl-carrier-protein S-malonyltransferase; PFAM: acyl transferase domain YP_004099301.1 COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR013751: IPR013747: IPR004655; KEGG: art:Arth_2467 3-oxoacyl-(acyl carrier protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; PRIAM: beta-ketoacyl-acyl-carrier-protein synthase III; SPTR: 3-oxoacyl-(acyl carrier protein) synthase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III YP_004099302.1 InterPro IPR006163: IPR003231: IPR009081; KEGG: aau:AAur_2437 acyl carrier protein; PFAM: phosphopantetheine-binding; SPTR: acyl carrier protein; PFAM: phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_004099303.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030: IPR014031: IPR017568; KEGG: ske:Sked_14080 3-oxoacyl-(acyl-carrier-protein) synthase II; PFAM: beta-ketoacyl synthase; SPTR: 3-oxoacyl-ACP synthase II; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: beta-ketoacyl synthase, N-terminal domain; beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004099304.1 COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: pfr:PFREUD_23600 hypothetical protein; PFAM: protein of unknown function UPF0027; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0027 YP_004099305.1 InterPro IPR003482; KEGG: cai:Caci_7795 transcription factor WhiB; PFAM: transcription factor WhiB; SPTR: transcription factor WhiB; PFAM: transcription factor WhiB YP_004099306.1 COGs: COG1403 Restriction endonuclease; InterPro IPR002711: IPR003615; KEGG: kfl:Kfla_6715 HNH endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; PFAM: HNH endonuclease YP_004099307.1 KEGG: aau:AAur_2439 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3145) YP_004099308.1 COGs: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase; InterPro IPR017941; KEGG: mlu:Mlut_20070 nitrite reductase (NAD(P)H), small subunit; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] domain YP_004099309.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001845: IPR001763; KEGG: rha:RHA1_ro11220 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; Rhodanese domain protein; SMART: regulatory protein ArsR; rhodanese; SPTR: Possible ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family; Rhodanese-like domain YP_004099310.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR005829; KEGG: mva:Mvan_5862 major facilitator superfamily transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004099311.1 KEGG: dal:Dalk_1377 protein of unknown function DUF81; SPTR: Histidinol-phosphate aminotransferase YP_004099312.1 InterPro IPR007712; KEGG: rop:ROP_29420 hypothetical protein; PFAM: plasmid stabilization system; SPTR: uncharacterized protein; PFAM: Plasmid stabilisation system protein YP_004099313.1 InterPro IPR006442; KEGG: rop:ROP_29430 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004099314.1 KEGG: sen:SACE_7264 hypothetical protein; SPTR: Prevent-host-death family protein YP_004099315.1 KEGG: cfl:Cfla_0603 hypothetical protein; SPTR: uncharacterized protein YP_004099316.1 KEGG: bcv:Bcav_2606 hypothetical protein; SPTR: uncharacterized protein YP_004099317.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: fal:FRAAL3368 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004099318.1 COGs: COG0798 Arsenite efflux pump ACR3 and related permease; InterPro IPR002657: IPR004706; KEGG: nfa:pnf2250 arsenic resistance transporter; PFAM: sodium symporter; SPTR: arsenic resistance transporter; TIGRFAM: arsenic resistance protein; PFAM: Sodium Bile acid symporter family; TIGRFAM: arsenic resistance protein YP_004099319.1 InterPro IPR010712; KEGG: mva:Mvan_5095 arsenite-activated ATPase ArsA; PFAM: Arsenical resistance operon trans-acting repressor ArsD; SPTR: Arsenite-activated ATPase ArsA; PFAM: Arsenical resistance operon trans-acting repressor ArsD YP_004099320.1 COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003593: IPR016300: IPR003348; KEGG: rop:ROP_00210 arsenite-transporting ATPase; PRIAM: Arsenite-transporting ATPase; SMART: AAA ATPase; SPTR: Arsenite-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA); TC 3.A.4.1.1 YP_004099321.1 COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: art:Arth_0213 protein tyrosine phosphatase; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: arsenate reductase; PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_004099322.1 InterPro IPR002126: IPR006626; KEGG: mlo:mll4444 hypothetical protein; PFAM: cadherin; SMART: cadherin; Parallel beta-helix repeat; SPTR: Mll4444 protein YP_004099323.1 COGs: COG4675 Microcystin-dependent protein; InterPro IPR011083; KEGG: mlo:mll4443 microcystin dependent protein MdpB; PFAM: Tail Collar domain protein; SPTR: Tail Collar domain protein; PFAM: Phage Tail Collar Domain YP_004099324.1 COGs: COG4675 Microcystin-dependent protein; InterPro IPR011083; KEGG: mlo:mll4442 microcystin dependent protein MdpB; PFAM: Tail Collar domain protein; SPTR: Microcystin dependent protein; MdpB; PFAM: Phage Tail Collar Domain YP_004099325.1 COGs: COG4675 Microcystin-dependent protein; InterPro IPR011083; KEGG: mlo:mll4441 microcystin dependent protein MdpB; PFAM: Tail Collar domain protein; SPTR: Microcystin dependent protein; MdpB; PFAM: Phage Tail Collar Domain YP_004099326.1 InterPro IPR000182; KEGG: mxa:MXAN_0328 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase, GNAT family; PFAM: acetyltransferase (GNAT) family YP_004099327.1 InterPro IPR006311: IPR017909; KEGG: sro:Sros_8988 twin-arginine translocation pathway signal; SPTR: Twin-arginine translocation pathway signal YP_004099328.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterProIPR018484: IPR018485: IPR006000: IPR019825: IPR 018483; KEGG: svi:Svir_04580 D-xylulose kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase YP_004099329.1 COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669: IPR013131: IPR013118; KEGG: kfl:Kfla_1360 mannitol dehydrogenase domain protein; PFAM: mannitol dehydrogenase; Mannitol dehydrogenase rossman domain; SPTR: mannitol dehydrogenase protein; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain YP_004099330.1 COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002347: IPR002198; KEGG: rxy:Rxyl_3000 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004099331.1 COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: mjl:Mjls_4735 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099332.1 COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: nda:Ndas_4000 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099333.1 COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059: IPR017909; KEGG: rop:ROP_25030 ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004099334.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060: IPR018062; KEGG: ach:Achl_1710 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004099335.1 InterPro IPR018649; KEGG: tbd:Tbd_2741 hypothetical protein; PFAM: protein of unknown function DUF2078, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2078) YP_004099336.1 COGs: COG2132 multicopper oxidase; InterProIPR011707: IPR001117: IPR011706: IPR006311: IPR 002355: IPR017909; KEGG: art:Arth_0198 multicopper oxidase type 3; PFAM: multicopper oxidase type 3; multicopper oxidase type 1; multicopper oxidase type 2; SPTR: Multicopper oxidase type 3; PFAM: Multicopper oxidase YP_004099337.1 KEGG: scb:SCAB_1751 hypothetical protein; SPTR: secreted protein YP_004099338.1 KEGG: aau:AAur_pTC10136 hypothetical protein; SPTR: uncharacterized protein YP_004099339.1 COGs: COG0348 polyferredoxin; InterPro IPR017900: IPR017896; KEGG: cfl:Cfla_3683 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004099340.1 KEGG: pin:Ping_1371 hypothetical protein; SPTR: uncharacterized protein YP_004099341.1 COGs: COG0121 glutamine amidotransferase; InterPro IPR000583: IPR017932; KEGG: rha:RHA1_ro04807 hypothetical protein; PFAM: glutamine amidotransferase class-II; SPTR: uncharacterized protein; PFAM: glutamine amidotransferases class-II YP_004099342.1 COGs: COG0178 excinuclease ATPase; InterPro IPR003439; KEGG: rha:RHA1_ro03835 UvrABC system protein A; PFAM: ABC transporter related; SPTR: UvrABC system protein A; PFAM: ABC transporter; TIGRFAM: excinuclease ABC subunit A YP_004099343.1 COGs: COG3213 Uncharacterized protein involved in response to NO; InterPro IPR010266; KEGG: pde:Pden_4044 NnrS family protein; PFAM: NnrS family protein; SPTR: NnrS family protein; PFAM: NnrS protein YP_004099344.1 COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: ach:Achl_0696 peptidase M23; PFAM: peptidase M23; SPTR: peptidase M23; PFAM: peptidase family M23 YP_004099345.1 COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: kra:Krad_1498 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: glutamate uptake system ATP-binding protein; PFAM: ABC transporter YP_004099346.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638: IPR018313; KEGG: jde:Jden_1593 extracellular solute-binding protein family 3; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: glutamate-binding protein of ABC transporter system; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004099347.1 COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515: IPR010065; KEGG: bfa:Bfae_22720 amino acid ABC transporter membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Amino acid ABC transporter membrane protein; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family YP_004099348.1 COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515: IPR010065; KEGG: mgi:Mflv_3971 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: glutamate transporter permease; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family YP_004099349.1 KEGG: ske:Sked_14030 hypothetical protein; SPTR: DNA primase YP_004099350.1 COGs: COG0358 DNA primase; InterProIPR002694: IPR013264: IPR006171: IPR019475: IPR 006154: IPR006295; KEGG: kse:Ksed_11920 DNA primase; PFAM: DNA primase catalytic core domain; TOPRIM domain-containing protein; DNA primase, DnaB-helicase binding domain; SMART: Toprim sub domain-containing protein; SPTR: DNA primase; TIGRFAM: DNA primase; PFAM: Toprim domain; CHC2 zinc finger; DNA primase catalytic core, N-terminal domain; DnaB-helicase binding domain of primase; TIGRFAM: DNA primase, catalytic core YP_004099351.1 COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR006674: IPR003607: IPR006261; KEGG: kse:Ksed_11910 deoxyguanosinetriphosphate triphosphohydrolase, PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: deoxyguanosinetriphosphate triphosphohydrolase-like protein; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, ; uncharacterized domain HDIG YP_004099352.1 KEGG: mgi:Mflv_5225 hypothetical protein; SPTR: uncharacterized protein YP_004099353.1 KEGG: bcv:Bcav_0104 hypothetical protein; SPTR: uncharacterized protein YP_004099354.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269: IPR004652: IPR018517; KEGG: kse:Ksed_11870 TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase; SPTR: transcriptional regulator, NifR3/Smm1 family protein; TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase (Dus); TIGRFAM: hypothetical protein YP_004099355.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: nda:Ndas_2192 alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: Predicted protein; PFAM: alpha/beta hydrolase fold YP_004099356.1 COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: kfl:Kfla_3476 rhodanese domain protein; PFAM: rhodanese; SMART: rhodanese; SPTR: rhodanese; PFAM: Rhodanese-like domain YP_004099357.1 KEGG: sro:Sros_2344 hypothetical protein; SPTR: uncharacterized protein YP_004099358.1 COGs: COG0803 ABC-type metal ion transporter periplasmic component/surface adhesin; InterPro IPR006129: IPR006128: IPR006127; KEGG: gob:Gobs_1602 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: ABC-transporter metal-binding lipoprotein; PFAM: Periplasmic solute binding protein family YP_004099359.1 COGs: COG1121 ABC-type Mn/Zn transporters ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: gob:Gobs_1601 ABC transporter related protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type Mn/Zn transporters ATPase component; PFAM: ABC transporter YP_004099360.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transporters permeases; InterPro IPR001626; KEGG: gob:Gobs_1600 ABC transporter; PFAM: ABC transporter; SPTR: metal transport ABC transporter; PFAM: ABC 3 transport family YP_004099361.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: mmi:MMAR_3669 zinc uptake regulation protein Zur; PFAM: ferric-uptake regulator; SPTR: Zinc uptake regulation protein Zur; PFAM: ferric uptake regulator family YP_004099362.1 COGs: COG0020 undecaprenyl pyrophosphate synthase; InterPro IPR001441: IPR018520; KEGG: kra:Krad_3373 undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Di-trans-poly-cis-decaprenylcistransferase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_004099363.1 COGs: COG1381 recombinational DNA repair protein (RecF pathway); InterPro IPR003717; KEGG: bcv:Bcav_1766 DNA repair protein RecO; PFAM: recombination protein O RecO; SPTR: DNA repair protein RecO; TIGRFAM: DNA repair protein RecO; PFAM: recombination protein O C terminal; recombination protein O N terminal; TIGRFAM: DNA repair protein RecO YP_004099364.1 COGs: COG3145 Alkylated DNA repair protein; KEGG: sma:SAV_1131 alkylated DNA repair protein; SPTR: alkylated DNA repair protein; manually curated YP_004099365.1 InterPro IPR010872: IPR017517; KEGG: nca:Noca_2467 hypothetical protein; PFAM: protein of unknown function DUF1503; SPTR: uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: uncharacterized Actinobacterial protein TIGR03083 YP_004099366.1 COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: cgt:cgR_1102 hypothetical protein; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase YP_004099367.1 KEGG: lme:LEUM_0908 hypothetical protein; SPTR: uncharacterized protein YP_004099368.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891: IPR013709: IPR005668: IPR002034; KEGG: kra:Krad_3377 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase, yeast type YP_004099369.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: nca:Noca_0392 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004099370.1 COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620: IPR006311: IPR018073; KEGG: tcu:Tcur_4232 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; manually curated; PFAM: EamA-like transporter family YP_004099371.1 COGs: COG1159 GTPase; InterPro IPR002917: IPR004044: IPR005662: IPR005225; KEGG: kse:Ksed_11760 GTP-binding protein Era; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; SPTR: GTP-binding protein era homolog; TIGRFAM: GTP-binding protein Era; small GTP-binding protein; PFAM: KH domain; GTPase of unknown function; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain YP_004099372.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550: IPR000644: IPR005170; KEGG: kse:Ksed_11750 CBS domain-containing protein; PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; SMART: CBS domain containing protein; SPTR: membrane protein; PFAM: CBS domain; Domain of unknown function DUF21; transporter associated domain YP_004099373.1 COGs: COG0319 metal-dependent hydrolase; InterPro IPR002036: IPR020549; KEGG: bcv:Bcav_1751 protein of unknown function UPF0054; PFAM: protein of unknown function UPF0054; SPTR: metalloprotease JNB_04990; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family YP_004099374.1 COGs: COG1702 phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714: IPR008162; KEGG: kra:Krad_3387 PhoH family protein; PFAM: PhoH family protein; SPTR: PhoH-like protein; PFAM: PhoH-like protein YP_004099375.1 COGs: COG2939 carboxypeptidase C (cathepsin A); InterPro IPR001563; KEGG: svi:Svir_32200 carboxypeptidase C (cathepsin A); PFAM: peptidase S10 serine carboxypeptidase; SPTR: carboxypeptidase C (Cathepsin A); PFAM: serine carboxypeptidase YP_004099376.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: nda:Ndas_0706 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: histidine triad (HIT) protein; PFAM: HIT domain YP_004099377.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014325: IPR014284; KEGG: ace:Acel_0787 ECF subfamily RNA polymerase sigma-24 factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_004099378.1 InterPro IPR019606: IPR018911; KEGG: kra:Krad_3401 hypothetical protein; PFAM: Lipoprotein LpqB, GerMN domain; Spore germination protein-like Gmad2, bacteria; SPTR: uncharacterized protein; PFAM: sporulation and spore germination; Immunoglobulin-like domain of bacterial spore germination YP_004099379.1 COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: cfl:Cfla_2208 protein of unknown function DUF558; PFAM: protein of unknown function DUF558; SPTR: uncharacterized protein; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family YP_004099380.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR003095: IPR001623: IPR001305: IPR002939: IPR 012724: IPR018253; KEGG: scb:SCAB_61561 chaperone protein DnaJ2; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: DnaJ protein; PFAM: DnaJ central domain (4 repeats); DnaJ C terminal region; DnaJ domain; TIGRFAM: chaperone protein DnaJ YP_004099381.1 COGs: COG1420 transcriptional regulator of heat shock gene; InterPro IPR001034: IPR021153: IPR002571; KEGG: sro:Sros_2289 heat-inducible transcription repressor HrcA; PFAM: Winged helix-turn-helix transcription repressor, HrcA-like; regulatory protein DeoR; SPTR: heat-inducible transcription repressor hrcA; TIGRFAM: heat-inducible transcription repressor HrcA; PFAM: DeoR-like helix-turn-helix domain; HrcA protein C terminal domain; TIGRFAM: heat shock gene repressor HrcA YP_004099382.1 KEGG: kse:Ksed_11680 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: protein of unknown function (DUF3097) YP_004099383.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR012394: IPR016160; KEGG: nda:Ndas_1930 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family YP_004099384.1 COGs: COG0635 coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197: IPR010723: IPR006638: IPR004559; KEGG: kra:Krad_3411 coproporphyrinogen III oxidase; PFAM: HemN domain protein; radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase YP_004099385.1 InterPro IPR014922; KEGG: scb:SCAB_7521 hypothetical protein; PFAM: Domain of unknown function DUF1801; SPTR: Conserved hypthetical protein; PFAM: Domain of unknown function (DU1801) YP_004099386.1 COGs: COG2365 protein tyrosine/serine phosphatase; InterPro IPR016130: IPR000387; KEGG: tcu:Tcur_2401 protein tyrosine/serine phosphatase; SPTR: protein tyrosine/serine phosphatase-like protein YP_004099387.1 COGs: COG0481 membrane GTPase LepA; InterProIPR000795: IPR004161: IPR000640: IPR013842: IPR 006297: IPR005225; KEGG: kra:Krad_3418 GTP-binding protein LepA; PFAM: GTP-binding protein LepA domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; GTP-binding protein LepA C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004099388.1 InterPro IPR013096; KEGG: kfl:Kfla_5681 cupin 2 conserved barrel domain protein; PFAM: cupin; SPTR: cupin; PFAM: Cupin domain YP_004099389.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439: IPR013611: IPR003593: IPR017871; KEGG: sro:Sros_8128 ABC Fe+3 transporter ATPase; PFAM: ABC transporter related; transport-associated OB domain-containing protein; SMART: ATPase AAA; SPTR: ABC Fe+3 transporter ATPase; PFAM: ABC transporter; TOBE domain YP_004099390.1 COGs: COG1178 ABC-type Fe3+ transporter permease component; InterPro IPR000515; KEGG: sro:Sros_8129 iron ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Iron ABC transporter permease; manually curated; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099391.1 COGs: COG1840 ABC-type Fe3+ transporter periplasmic component; InterPro IPR006059; KEGG: mgi:Mflv_3363 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein, family 1; PFAM: Bacterial extracellular solute-binding protein YP_004099392.1 KEGG: xce:Xcel_2206 hypothetical protein; SPTR: uncharacterized protein; PFAM: PemK-like protein YP_004099393.1 InterPro IPR002583; KEGG: kse:Ksed_17380 30S ribosomal protein S20P; PFAM: ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: ribosomal protein S20; PFAM: ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_004099394.1 COGs: COG1466 DNA polymerase III subunit delta; InterPro IPR005790: IPR010372; KEGG: bcv:Bcav_1739 DNA polymerase III delta subunit; PFAM: DNA polymerase III delta; SPTR: DNA-binding protein; TIGRFAM: DNA polymerase III subunit delta; PFAM: DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III subunit delta YP_004099395.1 COGs: COG1199 Rad3-related DNA helicase; InterPro IPR014001: IPR006555: IPR014013; KEGG: kse:Ksed_17400 DNA helicase, Rad3; SMART: helicase c2; DEAD-like helicase; SPTR: ATP-dependent helicase; PFAM: DEAD/DEAH box helicase YP_004099396.1 COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR000559: IPR000276: IPR020628; KEGG: sen:SACE_5619 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: formate--tetrahydrofolate ligase; SPTR: formate--tetrahydrofolate ligase; PFAM: formate--tetrahydrofolate ligase YP_004099397.1 COGs: COG2262 GTPase; InterPro IPR016496: IPR005225: IPR002917: IPR006073; KEGG: kse:Ksed_17490 GTP-binding protein HflX; PFAM: GTP-binding protein HSR1-related; SPTR: ATP/GTP-binding protein; TIGRFAM: GTP-binding proten HflX; small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX; small GTP-binding protein domain YP_004099398.1 COGs: COG2813 16S RNA G1207 methylase RsmC; InterPro IPR007848; KEGG: rsa:RSal33209_0730 16S rRNA m2G1207 methyltransferase; PFAM: methyltransferase small; SPTR: 16S rRNA m2G1207 methyltransferase; PFAM: methyltransferase small domain YP_004099399.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR011340: IPR000192; KEGG: gob:Gobs_4945 cysteine desulfurase family protein; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: aminotransferase; TIGRFAM: cysteine desulfurase family protein; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein, VC1184 subfamily YP_004099400.1 COGs: COG0253 diaminopimelate epimerase; InterPro IPR001653: IPR018510; KEGG: xce:Xcel_1253 diaminopimelate epimerase; PFAM: diaminopimelate epimerase; SPTR: diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; PFAM: diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase YP_004099401.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022: IPR002627; KEGG: kse:Ksed_17540 tRNA isopentenyltransferase MiaA; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA) YP_004099402.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: rsa:RSal33209_3308 peptide deformylase; PFAM: formylmethionine deformylase; SPTR: peptide deformylase; TIGRFAM: peptide deformylase; PFAM: polypeptide deformylase; TIGRFAM: peptide deformylase YP_004099403.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839: IPR006463: IPR006638: IPR020612: IPR 002792: IPR013848: IPR007197; KEGG: kse:Ksed_17650 tRNA-i(6)A37 thiotransferase enzyme MiaB; PFAM: protein of unknown function UPF0004; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: RNA modification enzyme, MiaB family; tRNA-i(6)A37 thiotransferase enzyme MiaB; PFAM: radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family YP_004099404.1 COGs: COG2353 conserved hypothetical protein; InterPro IPR007372; KEGG: nca:Noca_4605 YceI family protein; PFAM: YceI family protein; SPTR: uncharacterized protein; PFAM: YceI-like domain YP_004099405.1 COGs: COG2137 conserved hypothetical protein; InterPro IPR003783; KEGG: kse:Ksed_17680 hypothetical protein; PFAM: regulatory protein RecX; SPTR: Uncharacterized conserved protein; manually curated; PFAM: RecX family YP_004099406.1 COGs: COG0468 RecA/RadA recombinase; InterProIPR013765: IPR003593: IPR020584: IPR020588: IPR 020587: IPR001553; KEGG: kra:Krad_1492 RecA protein; PFAM: RecA domain protein; SMART: ATPase AAA; SPTR: protein recA; TIGRFAM: recA protein; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_004099407.1 COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: vap:Vapar_1354 Appr-1-p processing domain protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: Appr-1-p processing domain protein; PFAM: Macro domain YP_004099408.1 KEGG: art:Arth_1459 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3046) YP_004099409.1 InterPro IPR001387; KEGG: kra:Krad_1487 helix-turn-helix domain protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Helix-turn-helix domain protein; PFAM: Helix-turn-helix YP_004099410.1 COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: sgr:SGR_1767 competence-damage inducible protein; PFAM: damage inducible protein CinA; SPTR: Competence-damage inducible protein; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain YP_004099411.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR004570: IPR000462; KEGG: gob:Gobs_3938 CDP-diacylglycerol/glycerol-3-phosphate3-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004099412.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839: IPR005840: IPR006638: IPR020612: IPR 002792: IPR013848: IPR007197; KEGG: kra:Krad_1484 MiaB-like tRNA modifying enzyme YliG; PFAM: protein of unknown function UPF0004; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme YliG, TIGR01125; RNA modification enzyme, MiaB family YP_004099413.1 COGs: COG2355 Zn-dependent dipeptidase microsomal dipeptidase homolog; InterPro IPR008257; KEGG: gob:Gobs_2447 membrane dipeptidase; PFAM: peptidase M19 renal dipeptidase; PRIAM: membrane dipeptidase; SPTR: dipeptidase; PFAM: membrane dipeptidase (peptidase family M19) YP_004099414.1 KEGG: kse:Ksed_18070 ion channel; SPTR: ion channel YP_004099415.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593: IPR002543: IPR018541; KEGG: kse:Ksed_18080 DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: ATPase AAA; SPTR: DNA translocase FtsK; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family YP_004099416.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR020578: IPR000192; KEGG: kfl:Kfla_2985 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V YP_004099417.1 COGs: COG3021 conserved hypothetical protein; InterPro IPR005135; KEGG: sen:SACE_0425 endonuclease/exonuclease/phosphatase; PFAM: endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: endonuclease/exonuclease/phosphatase family YP_004099418.1 COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR020578: IPR011108; KEGG: xce:Xcel_1230 beta-lactamase domain protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_004099419.1 COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR005263: IPR020624: IPR020625: IPR002220; KEGG: sma:SAV_2516 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; manually curated; PFAM: dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase YP_004099420.1 COGs: COG0262 dihydrofolate reductase; InterPro IPR001796: IPR012259; KEGG: kfl:Kfla_5968 dihydrofolate reductase; PFAM: dihydrofolate reductase region; PRIAM: dihydrofolate reductase; SPTR: Probable dihydrofolate reductase oxidoreductase protein; PFAM: dihydrofolate reductase YP_004099421.1 COGs: COG0207 Thymidylate synthase; InterPro IPR000398: IPR020940; KEGG: nca:Noca_2311 thymidylate synthase; PFAM: thymidylate synthase; PRIAM: Thymidylate synthase; SPTR: Thymidylate synthase; TIGRFAM: thymidylate synthase; PFAM: Thymidylate synthase; TIGRFAM: thymidylate synthase YP_004099422.1 KEGG: avn:Avin_08770 hypothetical protein; SPTR: uncharacterized protein YP_004099423.1 COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR011884: IPR006058: IPR001041: IPR017927: IPR 008333: IPR001433: IPR001709: IPR001221; KEGG: kse:Ksed_09330 phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; SPTR: Phenylacetate-CoA oxygenase/reductase, PaaK subunit; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; oxidoreductase FAD-binding domain; oxidoreductase NAD-binding domain; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit YP_004099424.1 COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR011883: IPR002744; KEGG: kse:Ksed_09320 phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; SPTR: Phenylacetate-CoA oxygenase, PaaJ subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; manually curated; PFAM: Domain of unknown function DUF59; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit YP_004099425.1 COGs: COG3396 conserved hypothetical protein; InterPro IPR011882: IPR007814; KEGG: kse:Ksed_09310 phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaI subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit YP_004099426.1 COGs: COG3460 Uncharacterized protein of phenylacetate metabolism; InterPro IPR009359; KEGG: kse:Ksed_09300 phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; SPTR: Phenylacetate-CoA oxygenase, PaaH subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: Phenylacetic acid degradation B; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit YP_004099427.1 COGs: COG3396 conserved hypothetical protein; InterPro IPR011881: IPR007814; KEGG: kse:Ksed_09290 phenylacetate-CoA oxygenase subunit PaaA; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaG subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit YP_004099428.1 InterPro IPR000182; KEGG: kfl:Kfla_2969 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family YP_004099429.1 COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: kra:Krad_0206 AzlC family protein; PFAM: AzlC family protein; SPTR: membrane protein; PFAM: AzlC protein YP_004099430.1 InterPro IPR008407; KEGG: kra:Krad_0205 branched-chain amino acid transport; PFAM: branched-chain amino acid transport; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter (AzlD) YP_004099431.1 COGs: COG0289 dihydrodipicolinate reductase; InterPro IPR011770: IPR000846: IPR000182; KEGG: kfl:Kfla_2962 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; GCN5-related N-acetyltransferase; SPTR: dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase, N-terminus; dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_004099432.1 COGs: COG1185 polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); InterProIPR014069: IPR012162: IPR004087: IPR004088: IPR 003029: IPR001247: IPR015847: IPR015848: IPR018111; KEGG: kra:Krad_1466 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; polynucleotide phosphorylase, phosphorolytic RNA-binding; K Homology, type 1, subgroup; RNA binding S1 domain protein; PRIAM: polyribonucleotide nucleotidyltransferase; SMART: KH domain protein; SPTR: polyribonucleotide nucleotidyltransferase; TIGRFAM: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase; polyribonucleotide nucleotidyltransferase; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 1; polyribonucleotide nucleotidyltransferase, RNA binding domain; 3' exoribonuclease family, domain 2; TIGRFAM: polyribonucleotide nucleotidyltransferase; guanosine pentaphosphate synthetase I/polynucleotide phosphorylase YP_004099433.1 COGs: COG0184 ribosomal protein S15P/S13E; InterPro IPR005290: IPR000589; KEGG: kse:Ksed_09240 30S ribosomal protein S15P; PFAM: ribosomal protein S15; SPTR: 30S ribosomal protein S15P; TIGRFAM: ribosomal protein S15; PFAM: ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_004099434.1 KEGG: rha:RHA1_ro02113 hypothetical protein; SPTR: uncharacterized protein YP_004099435.1 COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; KEGG: msm:MSMEG_0159 formate dehydrogenase, subunit gamma; SPTR: formate dehydrogenase; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit YP_004099436.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR001949: IPR011538: IPR019554: IPR019575; KEGG: msm:MSMEG_0160 formate dehydrogenase subunit beta; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH oxidoreductase (Quinone), F subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004099437.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR006478: IPR017900: IPR006655: IPR001041: IPR 017896: IPR019574: IPR006963: IPR006656: IPR006657; KEGG: msm:MSMEG_0161 formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molydopterin dinucleotide-binding region; SPTR: formate dehydrogenase, subunit alpha; TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; 4Fe-4S binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, subunit alpha, archaeal-type YP_004099438.1 KEGG: mno:Mnod_0253 hypothetical protein; SPTR: uncharacterized protein; PFAM: NADH-dependant formate dehydrogenase delta subunit FdsD YP_004099439.1 COGs: COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR006258: IPR012999: IPR013027: IPR004099: IPR 000815; KEGG: nca:Noca_3518 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase YP_004099440.1 COGs: COG4129 membrane protein; InterPro IPR000843; KEGG: nca:Noca_3704 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF939) YP_004099441.1 COGs: COG0768 cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460; KEGG: tbi:Tbis_1685 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: peptidoglycan glycosyltransferase; SPTR: penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding protein dimerisation domain; TIGRFAM: penicillin-binding protein 2 YP_004099442.1 KEGG: kse:Ksed_09220 rod shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD YP_004099443.1 COGs: COG1792 cell shape-determining protein; InterPro IPR007221; KEGG: tcu:Tcur_1540 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: rod shape-determining protein; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC YP_004099444.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: fal:FRAAL1916 rod shape-determining protein MreB; PFAM: cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004099445.1 COGs: COG0105 nucleoside diphosphate kinase; InterPro IPR001564; KEGG: kse:Ksed_09190 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase YP_004099446.1 KEGG: kse:Ksed_09170 hypothetical protein; SPTR: uncharacterized protein YP_004099447.1 KEGG: nda:Ndas_1774 hypothetical protein; SPTR: uncharacterized protein YP_004099448.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645: IPR018109: IPR013221: IPR004101; KEGG: kse:Ksed_09160 folylpolyglutamate synthase/dihydrofolate synthase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: folylpolyglutamate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004099449.1 InterPro IPR000182; KEGG: cfl:Cfla_2792 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004099450.1 COGs: COG0060 isoleucyl-tRNA synthetase; InterProIPR002301: IPR001412: IPR002300: IPR013155: IPR 015905; KEGG: nca:Noca_1198 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: isoleucyl-tRNA synthetase; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); anticodon-binding domain; TIGRFAM: isoleucyl-tRNA synthetase YP_004099451.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR004113; KEGG: gob:Gobs_0127 FAD linked oxidase domain protein; PFAM: FAD linked oxidase; SPTR: FAD linked oxidase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase subunit GlcD YP_004099452.1 InterPro IPR000086; KEGG: sro:Sros_4212 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein YP_004099453.1 InterPro IPR017909: IPR008454; KEGG: mes:Meso_0048 hypothetical protein; PFAM: Cna B domain protein; SPTR: Conserved repeat domain; PFAM: Cna protein B-type domain YP_004099454.1 KEGG: pol:Bpro_2435 hypothetical protein; SPTR: uncharacterized protein YP_004099455.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638: IPR007197; KEGG: cai:Caci_7280 radical SAM protein; PFAM: radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: radical SAM superfamily YP_004099456.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845: IPR018294: IPR000873; KEGG: kfl:Kfla_2400 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: long-chain fatty-acid CoA ligase; PFAM: AMP-binding enzyme YP_004099457.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR018365: IPR001182; KEGG: fal:FRAAL1920 rod shape-determining membrane protein; cell elongation; PFAM: cell cycle protein; SPTR: Sfr protein; PFAM: cell cycle protein; TIGRFAM: rod shape-determining protein RodA YP_004099458.1 COGs: COG0196 FAD synthase; InterPro IPR004821: IPR002606: IPR015864: IPR015865; KEGG: ske:Sked_23420 FMN adenylyltransferase/riboflavin kinase; PFAM: FAD synthetase; riboflavin kinase; SPTR: riboflavin kinase/ FMN adenyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; manually curated; PFAM: riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain YP_004099459.1 COGs: COG0130 Pseudouridine synthase; InterPro IPR014780: IPR002501: IPR015225; KEGG: ach:Achl_1432 tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; tRNA pseudouridine synthase II; SPTR: TRNA pseudouridine synthase B; TIGRFAM: tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); tRNA Pseudouridine synthase II, C terminal; TIGRFAM: tRNA pseudouridine 55 synthase YP_004099460.1 COGs: COG0858 ribosome-binding factor A; InterPro IPR000238: IPR020053; KEGG: bfa:Bfae_10330 ribosome-binding factor A; PFAM: ribosome-binding factor A; SPTR: ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; PFAM: ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_004099461.1 COGs: COG0532 translation initiation factor 2 (IF-2; GTPase); InterProIPR000178: IPR005225: IPR006847: IPR000795: IPR 004161; KEGG: cfl:Cfla_1510 translation initiation factor IF-2; PFAM: protein synthesis factor GTP-binding; translation initiation factor IF-2 domain-containing protein; elongation factor Tu domain 2 protein; SPTR: translation initiation factor IF-2; TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; manually curated; PFAM: Elongation factor Tu domain 2; translation-initiation factor 2; translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_004099462.1 COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: nfa:nfa40675 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: uncharacterized protein; manually curated; PFAM: protein of unknown function (DUF448) YP_004099463.1 COGs: COG0195 transcription elongation factor; InterPro IPR010213: IPR004088: IPR003029: IPR013735; KEGG: cfl:Cfla_1508 transcription termination factor NusA; PFAM: NusA domain-containing protein; SPTR: transcription elongation factor NusA; TIGRFAM: transcription termination factor NusA; PFAM: NusA N-terminal domain; TIGRFAM: transcription termination factor NusA YP_004099464.1 InterPro IPR020790: IPR003728; KEGG: tcu:Tcur_3333 protein of unknown function DUF150; PFAM: protein of unknown function DUF150; SPTR: ribosome maturation factor rimP; PFAM: Uncharacterised BCR, YhbC family COG0779 YP_004099465.1 KEGG: nml:Namu_5076 serine/threonine protein kinase; SPTR: uncharacterized protein YP_004099466.1 COGs: COG3570 Streptomycin 6-kinase; InterPro IPR006748; KEGG: kfl:Kfla_2389 antimicrobial 6-kinase; PFAM: aminoglycoside/hydroxyurea antibiotic resistance kinase; PRIAM: Streptomycin 6-kinase; SPTR: antimicrobial 6-kinase; PFAM: Aminoglycoside/hydroxyurea antibiotic resistance kinase YP_004099467.1 COGs: COG1331 Highly conserved protein containing a thioredoxin domain; KEGG: gob:Gobs_0945 protein of unknown function DUF255; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF255 YP_004099468.1 COGs: COG1477 membrane-associated lipoprotein involved in thiamine biosynthesis; InterPro IPR003374; KEGG: sma:SAV_6768 thiamine biosynthesis lipoprotein precursor; PFAM: ApbE family lipoprotein; SPTR: thiamine biosynthesis lipoprotein; PFAM: ApbE family YP_004099469.1 InterPro IPR007329; KEGG: sma:SAV_6771 hypothetical protein; PFAM: FMN-binding domain protein; SPTR: uncharacterized protein; PFAM: FMN-binding domain YP_004099470.1 COGs: COG4097 ferric reductase; InterProIPR017927: IPR013130: IPR008333: IPR001433: IPR 001221; KEGG: amd:AMED_3689 oxidoreductase; PFAM: ferric reductase domain protein transmembrane component domain; oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: oxidoreductase; PFAM: ferric reductase like transmembrane component; oxidoreductase NAD-binding domain YP_004099471.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: nca:Noca_0959 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004099472.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834: IPR005833; KEGG: nca:Noca_3196 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Hydrolase; PFAM: haloacid dehalogenase-like hydrolase YP_004099473.1 COGs: COG0442 prolyl-tRNA synthetase; InterProIPR004500: IPR006195: IPR002314: IPR007214: IPR 004154: IPR002316; KEGG: nca:Noca_3197 prolyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); YbaK/prolyl-tRNA synthetase associated region; anticodon-binding domain protein; SPTR: prolyl-tRNA synthetase; TIGRFAM: prolyl-tRNA synthetase; PFAM: anticodon binding domain; YbaK / prolyl-tRNA synthetases associated domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II YP_004099474.1 COGs: COG3393 acetyltransferase; InterPro IPR000182; KEGG: nca:Noca_3472 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: FR47-like protein YP_004099475.1 COGs: COG4270 membrane protein; InterPro IPR006311; KEGG: kfl:Kfla_3028 membrane protein-like protein; SPTR: uncharacterized protein YP_004099476.1 COGs: COG3393 acetyltransferase; InterPro IPR016794: IPR000182; KEGG: kse:Ksed_11380 predicted acyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004099477.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; InterPro IPR004588: IPR016425: IPR000425; KEGG: nca:Noca_3202 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PFAM: IspG family protein; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004099478.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR001478: IPR008915; KEGG: kse:Ksed_11310 predicted membrane-associated Zn-dependent protease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease; PFAM: peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP YP_004099479.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR003821: IPR013512: IPR013644; KEGG: kse:Ksed_11300 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004099480.1 InterPro IPR011576; KEGG: kfl:Kfla_2374 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: pyridoxamine 5'-phosphate oxidase YP_004099481.1 COGs: COG4290 Guanyl-specific ribonuclease Sa; InterPro IPR000026; KEGG: ach:Achl_0858 guanine-specific ribonuclease N1 and T1; PFAM: guanine-specific ribonuclease N1 and T1; SPTR: Guanyl-specific ribonuclease SA; PFAM: ribonuclease YP_004099482.1 InterPro IPR000468; KEGG: xac:XAC2388 hypothetical protein; PFAM: Barstar (barnase inhibitor); SPTR: uncharacterized protein; PFAM: Barstar (barnase inhibitor) YP_004099483.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR007694; KEGG: ttr:Tter_1028 DnaB domain protein helicase domain protein; PFAM: DnaB domain protein helicase; SPTR: DnaB domain protein helicase; PFAM: DnaB-like helicase C terminal domain YP_004099484.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: svi:Svir_30180 succinate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: succinate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase YP_004099485.1 COGs: COG1748 saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: mkm:Mkms_5034 saccharopine dehydrogenase; PFAM: saccharopine dehydrogenase; SPTR: ATP binding protein; PFAM: saccharopine dehydrogenase YP_004099486.1 COGs: COG1177 ABC-type spermidine/putrescine transport system permease II; InterPro IPR000515; KEGG: scb:SCAB_25731 polyamine transporter; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: polyamine ABC transporter integral membrane protein; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099487.1 COGs: COG1176 ABC-type spermidine/putrescine transport system permease I; InterPro IPR000515; KEGG: sco:SCO5669 polyamine ABC-transporter integral memb rane protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: polyamine ABC-transporter integral membrane protein; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099488.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterProIPR005893: IPR003593: IPR017871: IPR003439: IPR 013611; KEGG: nca:Noca_3228 spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter; transport-associated OB domain-containing protein; SMART: ATPase AAA; SPTR: Spermidine/putrescine ABC transporter ATPase; TIGRFAM: spermidine/putrescine ABC transporter ATPase; PFAM: ABC transporter; TOBE domain; TIGRFAM: spermidine/putrescine ABC transporter ATP-binding subunit YP_004099489.1 COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR017909: IPR006059: IPR001188; KEGG: sgr:SGR_1837 polyamine ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004099490.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: kra:Krad_0841 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family; TIGRFAM: 1-pyrroline dehydrogenase YP_004099491.1 COGs: COG1522 transcriptional regulators; InterPro IPR019888: IPR000485: IPR019887; KEGG: scb:SCAB_25851 transcriptional regulator; PFAM: transcription regulator AsnC-type-like; SMART: transcription regulator AsnC-type; SPTR: AsnC-family transcriptional regulator; PFAM: HTH domain; AsnC family YP_004099492.1 COGs: COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814; KEGG: mgi:Mflv_4862 hypothetical protein; PFAM: aminotransferase class-III; SPTR: uncharacterized protein; PFAM: Aminotransferase class-III YP_004099493.1 KEGG: cmi:CMM_1413 hypothetical protein; SPTR: uncharacterized protein YP_004099494.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: kse:Ksed_17720 predicted permease; PFAM: Auxin Efflux Carrier; SPTR: transport integral membrane protein; PFAM: membrane transporter YP_004099495.1 KEGG: kse:Ksed_11250 predicted Rossmann fold nucleotide-binding protein; SPTR: uncharacterized protein; PFAM: Possible lysine decarboxylase YP_004099496.1 COGs: COG1232 protoporphyrinogen oxidase; InterPro IPR004572: IPR002937; KEGG: nca:Noca_3672 protoporphyrinogen oxidase; PFAM: amine oxidase; SPTR: protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: protoporphyrinogen oxidase YP_004099497.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017200: IPR007197; KEGG: nca:Noca_4381 radical SAM domain-containing protein; PFAM: radical SAM protein; SPTR: radical SAM protein; PFAM: radical SAM superfamily YP_004099498.1 COGs: COG0365 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845: IPR000873; KEGG: sro:Sros_1890 propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: acetyl-CoA synthetase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme YP_004099499.1 COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383: IPR007197; KEGG: kse:Ksed_11240 ribosomal RNA large subunit methyltransferase N; PFAM: radical SAM protein; SPTR: ribosomal RNA large subunit methyltransferase N; TIGRFAM:radical SAM protein; PFAM: radical SAM superfamily; TIGRFAM:radical SAM protein YP_004099500.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904: IPR002198: IPR002347; KEGG: mkm:Mkms_1869 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004099501.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: gob:Gobs_3987 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family YP_004099502.1 COGs: COG0233 ribosome recycling factor; InterPro IPR002661: IPR015998; KEGG: xce:Xcel_1183 ribosome recycling factor; PFAM: ribosome recycling factor; SPTR: ribosome-recycling factor; TIGRFAM: ribosome recycling factor; PFAM: ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_004099503.1 COGs: COG0528 Uridylate kinase; InterPro IPR015963: IPR011817: IPR001048; KEGG: nca:Noca_3241 uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: UMP kinase; SPTR: Uridylate kinase; TIGRFAM: uridylate kinase; PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase YP_004099504.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sna:Snas_2195 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V YP_004099505.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 001099: IPR004358; KEGG: sna:Snas_5524 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; chalcone and stilbene synthase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: two-component system sensor kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004099506.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: sgr:SGR_2224 two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004099507.1 COGs: COG2210 conserved hypothetical protein; KEGG: nml:Namu_0352 hypothetical protein; SPTR: uncharacterized protein YP_004099508.1 COGs: COG2920 Dissimilatory sulfite reductase (desulfoviridin) subunit gamma; InterPro IPR007453; KEGG: nml:Namu_2561 sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; SPTR: Sulfur relay protein, TusE/DsrC/DsvC family; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC like protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family YP_004099509.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027; KEGG: nml:Namu_0350 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004099510.1 COGs: COG0264 translation elongation factor Ts; InterPro IPR001816: IPR018101: IPR000449: IPR014039; KEGG: kse:Ksed_11200 translation elongation factor Ts (EF-Ts); PFAM: translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; SPTR: Elongation factor Ts; TIGRFAM: translation elongation factor Ts; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts YP_004099511.1 COGs: COG0052 ribosomal protein S2; InterPro IPR005706: IPR018130: IPR001865; KEGG: xce:Xcel_1180 ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_004099512.1 KEGG: art:Arth_2689 hypothetical protein; SPTR: uncharacterized protein YP_004099513.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176; KEGG: stp:Strop_3861 aminotransferase; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II YP_004099514.1 InterPro IPR016047; KEGG: rer:RER_25410 hypothetical protein; PFAM: peptidase M23; SPTR: M23 peptidase domain protein; PFAM: peptidase family M23 YP_004099515.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: aau:AAur_2440 tyrosine recombinase XerC; PFAM: integrase; integrase; SPTR: Tyrosine recombinase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: tyrosine recombinase XerC YP_004099516.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: aau:AAur_pTC10235 integral membrane protein; PFAM: protein of unknown function DUF81; SPTR: integral membrane protein; PFAM: Sulfite exporter TauE/SafE YP_004099517.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: kra:Krad_1409 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_004099518.1 COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482: IPR003593: IPR013032: IPR000523; KEGG: kra:Krad_1408 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: ATPase AAA; SPTR: uncharacterized protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein YP_004099519.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: nca:Noca_3248 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein Noca_3248; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252 YP_004099520.1 InterPro IPR019592; KEGG: sen:SACE_6046 hypothetical protein; PFAM: protein of unknown function DUF2469; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2469) YP_004099521.1 COGs: COG0164 ribonuclease HII; InterPro IPR001352; KEGG: kra:Krad_1405 ribonuclease H; PFAM: ribonuclease HII/HIII; PRIAM: ribonuclease H; SPTR: ribonuclease; PFAM: ribonuclease HII YP_004099522.1 InterPro IPR000223: IPR019758: IPR019759; KEGG: kra:Krad_1404 signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; SPTR: signal peptidase; TIGRFAM: signal peptidase I; PFAM: peptidase S26; peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004099523.1 InterPro IPR000223: IPR019758: IPR019759; KEGG: kra:Krad_1403 signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; manually curated; PFAM: peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004099524.1 COGs: COG0335 ribosomal protein L19; InterPro IPR001857: IPR018257; KEGG: gob:Gobs_4003 ribosomal protein L19; PFAM: ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: ribosomal protein L19; PFAM: ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_004099525.1 COGs: COG0390 ABC-type uncharacterized transporter permease; KEGG: pfr:PFREUD_09290 ABC-type transporter permease component; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0014); TIGRFAM: conserved hypothetical protein TIGR00245 YP_004099526.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; InterPro IPR002649: IPR000182: IPR016009; KEGG: nca:Noca_3256 tRNA (guanine37-N1) methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; GCN5-related N-acetyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: TRNA-(Guanine-N1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (Guanine-1)-methyltransferase; acetyltransferase (GNAT) family; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_004099527.1 COGs: COG0806 RimM protein required for 16S rRNA processing; InterPro IPR011961: IPR002676: IPR007903; KEGG: nca:Noca_3257 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; SPTR: ribosome maturation factor rimM; TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_004099528.1 COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR020627: IPR004088; KEGG: jde:Jden_0986 KH domain protein; SPTR: uncharacterized protein YP_004099529.1 COGs: COG0228 ribosomal protein S16; InterPro IPR000307: IPR020592; KEGG: kse:Ksed_11040 30S ribosomal protein S16P; PFAM: ribosomal protein S16; SPTR: 30s ribosomal protein s16; TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_004099530.1 COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; KEGG: kse:Ksed_11030 acetyltransferase, ribosomal protein N-acetylase; SPTR: acetyltransferase, ribosomal protein N-acetylase YP_004099531.1 COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: sma:SAV_6403 hypothetical protein; PFAM: amidohydrolase; SPTR: uncharacterized protein; PFAM: Amidohydrolase family YP_004099532.1 COGs: COG0541 Signal recognition particle GTPase; InterProIPR004780: IPR003593: IPR000897: IPR013822: IPR 004125; KEGG: kse:Ksed_10980 signal recognition particle subunit FFH/SRP54 (SRP54); PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; Signal peptide binding (SRP54) M- domain protein; SMART: ATPase AAA; SPTR: Signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein YP_004099533.1 COGs: COG2844 UTP:GlnB (protein PII) uridylyltransferase; InterProIPR010043: IPR003607: IPR013546: IPR006674: IPR 002912; KEGG: kra:Krad_1395 PII uridylyl-transferase; PFAM: GlnD PII-uridylyltransferase; metal-dependent phosphohydrolase HD sub domain; amino acid-binding ACT domain protein; PRIAM: [protein-PII] uridylyltransferase; SMART: metal-dependent phosphohydrolase HD region; SPTR: PII uridylyl-transferase; TIGRFAM: protein-P-II uridylyltransferase; PFAM: GlnD PII-uridylyltransferase; HD domain; TIGRFAM: [protein-PII] uridylyltransferase YP_004099534.1 COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR002332: IPR002187; KEGG: ace:Acel_1565 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II YP_004099535.1 COGs: COG0004 Ammonia permease; InterPro IPR001905: IPR018047; KEGG: msm:MSMEG_2425 ammonium transporter; PFAM: ammonium transporter; SPTR: Low affinity ammonium uptake protein; TIGRFAM: ammonium transporter; PFAM: Ammonium transporter Family; TIGRFAM: ammonium transporter; TC 1.A.11 YP_004099536.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR004390: IPR003593: IPR000897: IPR013822; KEGG: kse:Ksed_10960 signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; SPTR: prokaryotic docking protein; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_004099537.1 COGs: COG1196 chromosome segregation ATPase; InterPro IPR011890: IPR017871: IPR003395: IPR010935; KEGG: cfl:Cfla_1462 chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain-containing protein; SPTR: chromosome associated protein; TIGRFAM: chromosome segregation protein SMC; PFAM: RecF/RecN/SMC N terminal domain; SMC proteins Flexible Hinge Domain; TIGRFAM: chromosome segregation protein SMC, common bacterial type YP_004099538.1 KEGG: fre:Franean1_3436 hypothetical protein; SPTR: uncharacterized protein YP_004099539.1 KEGG: ddr:Deide_15770 hypothetical protein; SPTR: uncharacterized protein YP_004099540.1 COGs: COG3576 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; InterPro IPR011576; KEGG: azl:AZL_002750 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: pyridoxamine 5'-phosphate oxidase YP_004099541.1 COGs: COG1605 chorismate mutase; InterPro IPR010951: IPR002701: IPR020822; KEGG: sgr:SGR_5509 chorismate mutase; PFAM: chorismate mutase, type II; SPTR: chorismate mutase; TIGRFAM: chorismate mutase; PFAM: chorismate mutase type II; TIGRFAM: monofunctional chorismate mutase, alpha proteobacterial type YP_004099542.1 COGs: COG1254 acylphosphatase; InterPro IPR017968: IPR001792: IPR020456; KEGG: kse:Ksed_10920 acylphosphatase; PFAM: acylphosphatase; SPTR: acylphosphatase; PFAM: acylphosphatase YP_004099543.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: bcv:Bcav_3022 acyltransferase 3; PFAM: acyltransferase 3; SPTR: Lipopolysaccharide modification acyltransferase; PFAM: acyltransferase family YP_004099544.1 COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: nca:Noca_4613 thimet oligopeptidase; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; PRIAM: Thimet oligopeptidase; SPTR: Thimet oligopeptidase; PFAM: peptidase family M3 YP_004099545.1 COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: tbi:Tbis_2163 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase YP_004099546.1 COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterProIPR000191: IPR020629: IPR000214: IPR012319: IPR 015886: IPR010663; KEGG: sen:SACE_6099 formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase catalytic domain protein; DNA glycosylase/AP lyase, H2TH DNA-binding; PRIAM: DNA-formamidopyrimidine glycosylase; SPTR: Formamidopyrimidine-DNA glycosylase; TIGRFAM: formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; Zinc finger found in FPG and IleRS; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg) YP_004099547.1 COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR011907: IPR000999: IPR001159; KEGG: nda:Ndas_0212 ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; PRIAM: ribonuclease III; SMART: ribonuclease III; double-stranded RNA binding domain protein; SPTR: ribonuclease III; TIGRFAM: ribonuclease III; PFAM: Double-stranded RNA binding motif; RNase3 domain; TIGRFAM: ribonuclease III, bacterial YP_004099548.1 InterPro IPR002677; KEGG: cfl:Cfla_2294 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein family; TIGRFAM: ribosomal protein L32 YP_004099549.1 COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: cfl:Cfla_2295 protein of unknown function DUF177; PFAM: protein of unknown function DUF177; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1399 YP_004099550.1 COGs: COG0669 phosphopantetheine adenylyltransferase; InterPro IPR004821: IPR001980: IPR018062: IPR004820; KEGG: svi:Svir_09450 phosphopantetheine adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: phosphopantetheine adenylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_004099551.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398: IPR002052; KEGG: nda:Ndas_0208 methyltransferase; PFAM: Conserved hypothetical protein CHP00095; SPTR: methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family YP_004099552.1 COGs: COG1200 RecG-like helicase; InterProIPR014001: IPR001650: IPR014021: IPR004365: IPR 011545; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase; nucleic acid binding OB-fold tRNA/helicase-type; helicase; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG YP_004099553.1 COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR019986: IPR004007; KEGG: sgr:SGR_1915 dihydroxyacetone kinase; PFAM: Dak phosphatase; SPTR: dihydroxyacetone kinase; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: DAK2 domain; TIGRFAM: DAK2 domain fusion protein YloV YP_004099554.1 COGs: COG3001 conserved hypothetical protein; InterPro IPR016477: IPR002575; KEGG: cmi:CMM_1084 sugar kinase; PFAM: aminoglycoside phosphotransferase; SPTR: uncharacterized protein; PFAM: fructosamine kinase YP_004099555.1 COGs: COG0227 ribosomal protein L28; InterPro IPR001383; KEGG: scb:SCAB_26481 50S ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_004099556.1 COGs: COG0611 thiamine monophosphate kinase; InterPro IPR006283: IPR000728: IPR010918; KEGG: kse:Ksed_10790 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: thiamine-phosphate kinase; SPTR: thiamine monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase YP_004099557.1 InterPro IPR019887; KEGG: kfl:Kfla_4827 transcriptional regulator, AsnC family; PFAM: transcription regulator AsnC-type-like; SPTR: uncharacterized protein; PFAM: AsnC family YP_004099558.1 KEGG: kse:Ksed_10780 hypothetical protein; SPTR: Secreted protein; PFAM: protein of unknown function (DUF3515) YP_004099559.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterProIPR005905: IPR000291: IPR011761: IPR011127: IPR 011095; KEGG: ske:Sked_11160 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-ala D-ala ligase N-terminus; D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_004099560.1 COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_3292 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: L,L-cystathionine gamma-Lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004099561.1 COGs: COG0240 glycerol-3-phosphate dehydrogenase; InterPro IPR006168: IPR011128: IPR006109; KEGG: kse:Ksed_10760 glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YP_004099562.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: cfl:Cfla_2313 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004099563.1 COGs: COG1920 conserved hypothetical protein; InterPro IPR002835; KEGG: tbi:Tbis_2795 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: 2-phospho-L-lactate guanylyltransferase CofC; PFAM: Uncharacterized protein conserved in bacteria (DUF2064); TIGRFAM: 2-phospho-L-lactate guanylyltransferase CofC YP_004099564.1 KEGG: cai:Caci_8046 hypothetical protein; SPTR: uncharacterized protein YP_004099565.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119: IPR020816; KEGG: sma:SAV_2684 histone-like DNA-binding protein; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: histone-like bacterial DNA-binding protein; PFAM: Bacterial DNA-binding protein YP_004099566.1 COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR004431: IPR000573; KEGG: art:Arth_2518 isopropylmalate isomerase small subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: 3-isopropylmalate dehydratase small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_004099567.1 COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR004430: IPR018136: IPR001030; KEGG: ami:Amir_6006 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: 3-isopropylmalate dehydratase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit YP_004099568.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: ske:Sked_11090 IclR family transcriptional regulator; PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: IclR-family transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004099569.1 KEGG: lel:LELG_03951 hypothetical protein; SPTR: Predicted protein YP_004099570.1 InterPro IPR002477: IPR005490; KEGG: nca:Noca_0518 peptidoglycan binding domain-containing protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; peptidoglycan-binding protein; SPTR: Lipoprotein; PFAM: peptidoglycan binding domain; L,D-transpeptidase catalytic domain YP_004099571.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019944: IPR019945: IPR020003: IPR016048; KEGG: nfa:nfa53550 F420-dependent glucose-6-phosphate dehydrogenase; PFAM: Luciferase-like, subgroup; SPTR: F420-dependent glucose-6-phosphate dehydrogenase; TIGRFAM: glucose-6-phosphate dehydrogenase, F420-dependent; F420-dependent oxidoreductase, G6PDH family; PFAM: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase, G6PDH family; glucose-6-phosphate dehydrogenase, F420-dependent YP_004099572.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402: IPR005834: IPR005833; KEGG: tpr:Tpau_2297 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004099573.1 COGs: COG0008 glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR004527: IPR001412: IPR020058: IPR020060; KEGG: ace:Acel_0714 glutamyl-tRNA synthetase; PFAM: glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: glutamyl-tRNA synthetase; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004099574.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: ske:Sked_10990 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family YP_004099575.1 InterPro IPR017909; KEGG: spu:585658 hypothetical LOC585658; SPTR: uncharacterized protein YP_004099576.1 KEGG: cfl:Cfla_1195 hypothetical protein; SPTR: uncharacterized protein YP_004099577.1 InterPro IPR001647: IPR003012; KEGG: cmi:CMM_1624 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004099578.1 COGs: COG0502 Biotin synthase; InterPro IPR002684: IPR006638: IPR007197: IPR010722; KEGG: sen:SACE_4683 biotin synthase; PFAM: biotin and thiamin synthesis associated; radical SAM protein; PRIAM: Biotin synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase; TIGRFAM: biotin synthase; PFAM: radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: biotin synthetase YP_004099579.1 COGs: COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005815: IPR005814; KEGG: rsa:RSal33209_0558 sdenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; SPTR: Sdenosylmethionine-8-amino-7-oxononanoate aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase YP_004099580.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004472: IPR001917: IPR004839; KEGG: krh:KRH_02460 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; SPTR: 8-amino-7-oxononanoate synthase; TIGRFAM: dethiobiotin synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; dethiobiotin synthase YP_004099581.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR005675: IPR002034: IPR000891: IPR013709; KEGG: nca:Noca_3364 alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain-containing protein; pyruvate carboxyltransferase; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein YP_004099582.1 COGs: COG2071 glutamine amidotransferase; InterPro IPR017926: IPR011697; KEGG: ace:Acel_1848 peptidase C26; PFAM: peptidase C26; SPTR: uncharacterized protein; PFAM: peptidase C26 YP_004099583.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR002347; KEGG: nca:Noca_2585 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short chain dehydrogenase; PFAM: short chain dehydrogenase YP_004099584.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: amd:AMED_1809 phenylacetaldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: Probable aldehyde dehydrogenase AldC; PFAM: aldehyde dehydrogenase family YP_004099585.1 COGs: COG0174 glutamine synthetase; InterPro IPR008146; KEGG: ace:Acel_1851 L-glutamine synthetase; PFAM: glutamine synthetase catalytic region; PRIAM: glutamate--ammonia ligase; SPTR: glutamine synthetase; PFAM: glutamine synthetase, catalytic domain YP_004099586.1 COGs: COG2186 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: ace:Acel_1852 GntR family transcriptional regulator; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004099587.1 COGs: COG0531 Amino acid transporter; InterPro IPR002293: IPR004841; KEGG: ace:Acel_1853 amino acid permease-associated region; PFAM: amino acid permease-associated region; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease; TIGRFAM: amino acid permease (GABA permease); TC 2.A.3 YP_004099588.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150: IPR006379: IPR013200; KEGG: ske:Sked_07610 HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; SPTR: HAD-superfamily hydrolase, subfamily IIB; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004099589.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786: IPR018300: IPR001544; KEGG: nca:Noca_3367 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II YP_004099590.1 COGs: COG0473 isocitrate/isopropylmalate dehydrogenase; InterPro IPR019818: IPR001804; KEGG: bcv:Bcav_1417 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase YP_004099591.1 COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236: IPR006140: IPR006139: IPR002912; KEGG: cai:Caci_7791 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: phosphoglycerate dehydrogenase; SPTR: Probable D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase YP_004099592.1 COGs: COG2837 iron-dependent peroxidase; InterPro IPR006314: IPR017909; KEGG: svi:Svir_39250 Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; SPTR: Dyp-type peroxidase family; TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase family; TIGRFAM: Tat-translocated enzyme; Dyp-type peroxidase family YP_004099593.1 COGs: COG2847 conserved hypothetical protein; InterPro IPR007410; KEGG: bfa:Bfae_31000 hypothetical protein; PFAM: protein of unknown function DUF461; SPTR: Uncharacterized conserved protein; PFAM: protein of unknown function (DUF461) YP_004099594.1 KEGG: sro:Sros_3434 major facilitator transporter; SPTR: Major facilitator transporter YP_004099595.1 COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013023: IPR013116: IPR000506; KEGG: jde:Jden_1708 ketol-acid reductoisomerase; PFAM: acetohydroxy acid isomeroreductase catalytic domain-containing protein; acetohydroxy acid isomeroreductase; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: ketol-acid reductoisomerase; PFAM: acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase YP_004099596.1 COGs: COG0440 acetolactate synthase small (regulatory) subunit; InterPro IPR004789: IPR002912: IPR019455; KEGG: tcu:Tcur_3553 acetolactate synthase, small subunit; PFAM: acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit YP_004099597.1 COGs: COG0028 thiamine pyrophosphate-requiring protein; InterProIPR012846: IPR000399: IPR012001: IPR012000: IPR 011766; KEGG: tbi:Tbis_2821 acetolactate synthase large subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: acetolactate synthase; TIGRFAM: acetolactate synthase large subunit; PFAM: thiamine pyrophosphate enzyme, central domain; thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase large subunit YP_004099598.1 InterPro IPR000182; KEGG: nca:Noca_4606 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004099599.1 COGs: COG0129 dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR004404: IPR020558: IPR000581; KEGG: nfa:nfa11740 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: dihydroxy-acid dehydratase; SPTR: dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase YP_004099600.1 COGs: COG2062 phosphohistidine phosphatase SixA; InterPro IPR013078; KEGG: nca:Noca_2573 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: phosphohistidine phosphatase SixA, ; PFAM: phosphoglycerate mutase family YP_004099601.1 InterPro IPR003749; KEGG: aau:AAur_4051 ThiS family protein; PFAM: thiamineS protein; SPTR: ThiS family protein; PFAM: ThiS family YP_004099602.1 KEGG: aau:AAur_4052 hypothetical protein; SPTR: uncharacterized protein; PFAM: BNR/Asp-box repeat YP_004099603.1 COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140; KEGG: cai:Caci_6823 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; SPTR: dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_004099604.1 COGs: COG2258 conserved hypothetical protein; InterPro IPR005302; KEGG: mkm:Mkms_4238 MOSC domain-containing protein; PFAM: MOSC domain containing protein; SPTR: MOSC domain containing protein; PFAM: MOSC domain YP_004099605.1 COGs: COG2133 glucose/sorbosone dehydrogenase; KEGG: sco:SCO5508 oxidoreductase; SPTR: oxidoreductase; PFAM: glucose / Sorbosone dehydrogenase YP_004099606.1 KEGG: art:Arth_1429 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF937) YP_004099607.1 COGs: COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006424: IPR020830: IPR020828: IPR020829: IPR 020832; KEGG: aau:AAur_2411 glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; PRIAM: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase YP_004099608.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); InterPro IPR004413: IPR017958: IPR006075: IPR018027; KEGG: kse:Ksed_09830 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; PFAM: GatB region; Asn/Gln amidotransferase; SPTR: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit YP_004099609.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR004412: IPR020556: IPR000120; KEGG: nca:Noca_3436 aspartyl/glutamyl-tRNA amidotransferase subunit A; PFAM: amidase; PRIAM: amidase; SPTR: glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, subunit alpha; PFAM: amidase; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, subunit alpha YP_004099610.1 COGs: COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; InterPro IPR003837; KEGG: kra:Krad_1317 glutamyl-tRNA(Gln) amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase C subunit; SPTR: glutamyl-tRNA amidotransferase subunit C; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase subunit C YP_004099611.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: saq:Sare_1795 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: branched-chain amino acid transport permease; PFAM: Branched-chain amino acid transporter / permease YP_004099612.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: stp:Strop_1804 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: branched-chain amino acid transport permease; PFAM: Branched-chain amino acid transporter / permease YP_004099613.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR001828; KEGG: saq:Sare_1793 hypothetical protein; PFAM: extracellular ligand-binding receptor; SPTR: Predicted LivK, ABC-type branched-chain amino acid transporters, periplasmic component YP_004099614.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593: IPR017871: IPR003439; KEGG: saq:Sare_1792 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004099615.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593: IPR017871: IPR003439; KEGG: saq:Sare_1791 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC branched-chain amino acid family transporter ATPase; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004099616.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR001679: IPR013840: IPR001357: IPR018239: IPR 013839: IPR004150: IPR004149: IPR000445; KEGG: kse:Ksed_09780 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; helix-hairpin-helix motif; BRCT domain protein; SMART: NAD-dependent DNA ligase; BRCT domain protein; SPTR: DNA ligase; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; BRCA1 C Terminus (BRCT) domain; NAD-dependent DNA ligase C4 zinc finger domain; TIGRFAM: DNA ligase, NAD-dependent YP_004099617.1 InterPro IPR003961: IPR005490; KEGG: nca:Noca_3138 ErfK/YbiS/YcfS/YnhG family protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; SPTR: ErfK/YbiS/YcfS/YnhG family protein; PFAM: L,D-transpeptidase catalytic domain YP_004099618.1 COGs: COG0697 Permease of the drug/metabolite transporter (DMT) superfamily; InterPro IPR000620; KEGG: fal:FRAAL1392 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: integral membrane protein; PFAM: EamA-like transporter family YP_004099619.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006091: IPR006090; KEGG: svi:Svir_30280 acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Probable acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004099620.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006090; KEGG: nca:Noca_2603 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004099621.1 InterPro IPR002629; KEGG: tcu:Tcur_3565 methionine synthase vitamin-B12 independent; PFAM: methionine synthase vitamin-B12 independent; SPTR: uncharacterized protein; PFAM: Cobalamin-independent synthase, Catalytic domain YP_004099622.1 InterPro IPR000182; KEGG: kfl:Kfla_6415 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004099623.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: kse:Ksed_09760 tRNA-specific 2-thiouridylase MnmA; SPTR: tRNA-specific 2-thiouridylase mnmA; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004099624.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: cai:Caci_1302 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: uncharacterized protein; PFAM: Aminotransferase class-V YP_004099625.1 KEGG: bur:Bcep18194_B1582 ATPase AAA, Clp; SPTR: AAA ATPase, Clp YP_004099626.1 COGs: COG2025 electron transfer flavoprotein alpha subunit; InterPro IPR001308: IPR018206: IPR014730: IPR014731; KEGG: kse:Ksed_09610 electron transfer flavoprotein, subunit alpha; PFAM: electron transfer flavoprotein subunit alpha; electron transfer flavoprotein alpha/beta-subunit; SPTR: electron transfer flavoprotein, subunit alpha; PFAM: electron transfer flavoprotein domain; electron transfer flavoprotein FAD-binding domain YP_004099627.1 COGs: COG2086 electron transfer flavoprotein beta subunit; InterPro IPR012255: IPR014730; KEGG: kfl:Kfla_4923 electron transfer flavoprotein alpha/beta-subunit; PFAM: electron transfer flavoprotein alpha/beta-subunit; SPTR: electron transfer flavoprotein subunit beta; PFAM: electron transfer flavoprotein domain YP_004099628.1 COGs: COG3323 conserved hypothetical protein; KEGG: bcv:Bcav_1828 protein of unknown function DUF34; SPTR: uncharacterized protein YP_004099629.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR001753; KEGG: nca:Noca_1813 short chain enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: Short chain enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase family YP_004099630.1 InterPro IPR010916; KEGG: kse:Ksed_09580 hypothetical protein; SPTR: uncharacterized protein YP_004099631.1 COGs: COG1523 type II secretory pathway pullulanase PulA and related glycosidase; InterProIPR011837: IPR006589: IPR001412: IPR004193: IPR 006047; KEGG: cfl:Cfla_1101 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: glycosyl hydrolase ( secreted protein); TIGRFAM: glycogen debranching enzyme GlgX; PFAM: carbohydrate-binding module 48 (Isoamylase N-terminal domain); alpha amylase, catalytic domain; TIGRFAM: glycogen debranching enzyme GlgX YP_004099632.1 COGs: COG0058 glucan phosphorylase; InterPro IPR011834: IPR000811; KEGG: kra:Krad_1298 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: phosphorylase; SPTR: phosphorylase; TIGRFAM: alpha-glucan phosphorylase; manually curated; PFAM: carbohydrate phosphorylase; protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases YP_004099633.1 COGs: COG0366 glycosidase; InterPro IPR006589: IPR001589: IPR022272: IPR006047; KEGG: nml:Namu_3176 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: alpha amylase, catalytic subdomain; PFAM: alpha amylase, catalytic domain; Domain of unknown function (DUF3416) YP_004099634.1 COGs: COG0366 glycosidase; InterPro IPR012810: IPR006589: IPR006047; KEGG: kse:Ksed_09530 trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Trehalose synthase; TIGRFAM: trehalose synthase; PFAM: alpha amylase, catalytic domain; TIGRFAM: trehalose synthase YP_004099635.1 COGs: COG3281 Uncharacterized protein probably involved in trehalose biosynthesis; InterPro IPR002575; KEGG: bcv:Bcav_1335 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: uncharacterized protein YP_004099636.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterProIPR006407: IPR006589: IPR004193: IPR006047: IPR 006048; KEGG: tcu:Tcur_3603 1,4-alpha-glucan branching enzyme; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; SPTR: 1,4-alpha-glucan-branching enzyme; TIGRFAM: 1,4-alpha-glucan branching enzyme; PFAM: alpha amylase, C-terminal all-beta domain; carbohydrate-binding module 48 (Isoamylase N-terminal domain); alpha amylase, catalytic domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase YP_004099637.1 COGs: COG0033 phosphoglucomutase; InterProIPR005852: IPR016066: IPR005844: IPR005845: IPR 005846: IPR005843; KEGG: nca:Noca_4438 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: phosphoglucomutase; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific YP_004099638.1 KEGG: cai:Caci_1075 phosphotransferase (aminonucleoside antibiotic resistance); SPTR: phosphotransferase (Aminonucleoside antibiotic resistance) YP_004099639.1 InterPro IPR000209; KEGG: kfl:Kfla_5233 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: subtilisin-like protease; PFAM: Subtilase family YP_004099640.1 COGs: COG3118 thioredoxin domain-containing protein; InterPro IPR017936; KEGG: bcv:Bcav_1333 thioredoxin; SPTR: thioredoxin; PFAM: thioredoxin YP_004099641.1 KEGG: art:Arth_2595 hypothetical protein; SPTR: uncharacterized protein YP_004099642.1 COGs: COG0011 conserved hypothetical protein; InterPro IPR002767; KEGG: nml:Namu_4567 protein of unknown function DUF77; PFAM: protein of unknown function DUF77; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF77; TIGRFAM: uncharacterized protein, MTH1187 family YP_004099643.1 COGs: COG1703 periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: nca:Noca_1798 LAO/AO transporter ATPase; PFAM: ArgK protein; SPTR: LAO/AO transporter ATPase; TIGRFAM: LAO/AO transporter ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transporter ATPase YP_004099644.1 COGs: COG0183 acetyl-CoA acetyltransferase; InterProIPR002155: IPR020615: IPR020610: IPR020613: IPR 020616: IPR020617; KEGG: rer:RER_38940 acetyl-CoA acetyltransferase; PFAM: thiolase-like; PRIAM: acetyl-CoA C-acetyltransferase; SPTR: acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase, C-terminal domain; thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_004099645.1 InterPro IPR017515: IPR004360; KEGG: gob:Gobs_4113 methylmalonyl-CoA epimerase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase YP_004099646.1 COGs: COG3387 glucoamylase and related glycosyl hydrolase; InterPro IPR011613; KEGG: kra:Krad_0219 glycoside hydrolase 15-related; PFAM: glycoside hydrolase 15-related; SPTR: glycoside hydrolase 15-related YP_004099647.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR017909: IPR002509; KEGG: afl:Aflv_1209 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase; PFAM: polysaccharide deacetylase YP_004099648.1 InterPro IPR005149; KEGG: tcu:Tcur_3551 PadR family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: transcriptional regulator; PFAM: transcriptional regulator PadR-like family; virulence activator alpha C-term YP_004099649.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593: IPR017871: IPR003439; KEGG: xce:Xcel_0700 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004099650.1 COGs: COG3127 ABC-type transporter involved in lysophospholipase L1 biosynthesis permease; InterPro IPR003838; KEGG: tcu:Tcur_3549 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004099652.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR010085: IPR013154: IPR013149; KEGG: scb:SCAB_17621 crotonyl CoA reductase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: Crotonyl CoA reductase; TIGRFAM: crotonyl-CoA reductase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: crotonyl-CoA reductase YP_004099653.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: kse:Ksed_09400 predicted permease; PFAM: protein of unknown function UPF0118; SPTR: membrane protein; PFAM: Domain of unknown function DUF20 YP_004099654.1 KEGG: bcv:Bcav_1315 hypothetical protein; SPTR: ATP/GTP-binding protein YP_004099655.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR006108; KEGG: kfl:Kfla_5009 3-hydroxyacyl-CoA dehydrogenase., 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; PRIAM: 3-hydroxybutyryl-CoA dehydrogenase., 3-hydroxybutyryl-CoA epimerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004099656.1 COGs: COG1637 nuclease of the RecB family; InterPro IPR002793; KEGG: cmi:CMM_2865 hypothetical protein; PFAM: protein of unknown function DUF91; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF91 YP_004099657.1 COGs: COG1811 Uncharacterized membrane protein Na+ channel or pump; InterPro IPR007563; KEGG: nca:Noca_3009 hypothetical protein; PFAM: protein of unknown function DUF554; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF554) YP_004099658.1 KEGG: kfl:Kfla_5010 hypothetical protein; SPTR: uncharacterized protein YP_004099659.1 COGs: COG1884 methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098: IPR006159: IPR006158: IPR006099; KEGG: gob:Gobs_4128 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: methylmalonyl-CoA mutase; SPTR: Coenzyme B12-dependent mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain YP_004099660.1 InterPro IPR002645; KEGG: kra:Krad_1274 anti-sigma-factor antagonist; PFAM: sulfate transporter/antisigma-factor antagonist STAS; SPTR: uncharacterized protein; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_004099661.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR005750: IPR001986; KEGG: kfl:Kfla_5039 UDP-N-acetylglucosamine1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR:UDP-N-acetylglucosamine1-carboxyvinyltransfera se; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004099662.1 COGs: COG2096 conserved hypothetical protein; InterPro IPR017858: IPR002779; KEGG: kse:Ksed_18150 ATP:cob(I)alamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: uncharacterized protein; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase YP_004099663.1 InterPro IPR019675; KEGG: kra:Krad_1272 hypothetical protein; PFAM: protein of unknown function DUF2550; SPTR: secreted protein; PFAM: protein of unknown function (DUF2550) YP_004099664.1 COGs: COG0355 F0F1-type ATP synthase subunit epsilon (mitochondrial subunit delta); InterPro IPR001469: IPR020546; KEGG: kse:Ksed_18170 F0F1-type ATP synthase, subunit epsilon; PFAM: ATPase, F1 complex, delta/subunit epsilon-like; SPTR: ATP synthase, epsilon chain; PFAM: ATP synthase, delta/Epsilon chain, beta-sandwich domain; TIGRFAM: ATP synthase, F1 subunit epsilon (delta in mitochondria) YP_004099665.1 KEGG: tpr:Tpau_4053 hypothetical protein; SPTR: uncharacterized protein YP_004099666.1 COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: fal:FRAAL1622 NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004099667.1 COGs: COG0055 F0F1-type ATP synthase beta subunit; InterProIPR005722: IPR003593: IPR020003: IPR004100: IPR 000194: IPR000793; KEGG: kse:Ksed_18200 F0F1 ATP synthase subunit beta; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPase alpha/subunit beta domain protein; SMART: AAA ATPase; SPTR: ATP synthase subunit B; TIGRFAM: ATP synthase F1 beta subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATP synthase, F1 subunit beta YP_004099668.1 COGs: COG0224 F0F1-type ATP synthase gamma subunit; InterPro IPR000131; KEGG: kra:Krad_1269 F0F1 ATP synthase subunit gamma; PFAM: H+transporting two-sector ATPase gamma; SPTR: ATP synthase gamma chain; TIGRFAM: ATP synthase F1 subunit gamma; PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 subunit gamma YP_004099669.1 COGs: COG0056 F0F1-type ATP synthase alpha subunit; InterProIPR005294: IPR020003: IPR004100: IPR000194: IPR 000793; KEGG: kse:Ksed_18220 F0F1 ATP synthase subunit alpha; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPase alpha/subunit beta domain protein; SPTR: ATP synthase subunit alpha; TIGRFAM: ATP synthase F1 subunit alpha; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: proton translocating ATP synthase, F1 subunit alpha YP_004099670.1 COGs: COG0712 F0F1-type ATP synthase subunit delta (mitochondrial oligomycin sensitivity protein); InterPro IPR000711: IPR020781; KEGG: kse:Ksed_18230 ATP synthase, F1 subunit delta; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; SPTR: ATP synthase delta chain; TIGRFAM: ATP synthase F1 subunit delta; PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 subunit delta YP_004099671.1 COGs: COG0711 F0F1-type ATP synthase subunit b; InterPro IPR005864: IPR002146; KEGG: kfl:Kfla_5050 ATP synthase F0 B subunit; PFAM: H+transporting two-sector ATPase B/B' subunit; SPTR: ATP synthase subunit b; TIGRFAM: ATP synthase F0 B subunit; PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_004099672.1 InterPro IPR000454: IPR020537: IPR002379; KEGG: kse:Ksed_18250 ATP synthase F0 C subunit; PFAM: H+transporting two-sector ATPase C subunit; SPTR: ATP synthase subunit c; PFAM: ATP synthase subunit C YP_004099673.1 COGs: COG0356 F0F1-type ATP synthase subunit a; InterPro IPR000568; KEGG: kse:Ksed_18260 ATP synthase F0 subunit alpha; PFAM: H+transporting two-sector ATPase alpha; SPTR: ATP synthase subunit a; TIGRFAM: ATP synthase F0 subunit alpha; PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_004099674.1 KEGG: tcu:Tcur_3923 hypothetical protein; SPTR: uncharacterized protein YP_004099675.1 KEGG: ach:Achl_2346 hypothetical protein; SPTR: ATP synthase protein I YP_004099676.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480: IPR018481; KEGG: kse:Ksed_18290 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: glycosyl transferase, family 4, conserved region; SPTR: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: glycosyl transferase family 4 YP_004099677.1 COGs: COG0112 glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: kse:Ksed_18300 serine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: glycine hydroxymethyltransferase; SPTR: glycine hydroxymethyltransferase; PFAM: serine hydroxymethyltransferase YP_004099678.1 COGs: COG0009 translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004099679.1 COGs: COG2358 TRAP-type uncharacterized transporter periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family YP_004099680.1 COGs: COG4666 TRAP-type uncharacterized transporter fused permeases; InterPro IPR011853: IPR010656; KEGG: ami:Amir_6905 TRAP transporter 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: TRAP transporter 4TM/12TM fusion protein; TIGRFAM: TRAP transporter 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter 4TM/12TM fusion protein YP_004099681.1 COGs: COG2890 methylase of polypeptide chain release factors; InterPro IPR004556: IPR019874: IPR007848; KEGG: kra:Krad_1259 modification methylase, HemK family; PFAM: methyltransferase small; SPTR: methylase; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; modification methylase, HemK family; PFAM: methyltransferase small domain; TIGRFAM: HemK family methylases; protein-(glutamine-N5) methyltransferase, release factor-specific YP_004099682.1 COGs: COG0216 protein chain release factor A; InterPro IPR004373: IPR000352: IPR005139; KEGG: kra:Krad_1257 peptide chain release factor 1; PFAM: class I peptide chain release factor; PCRF domain protein; SPTR: peptide chain release factor 1; TIGRFAM: peptide chain release factor 1; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1 YP_004099683.1 COGs: COG0254 ribosomal protein L31; InterPro IPR002150; KEGG: nca:Noca_1750 50S ribosomal protein L31; PFAM: ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_004099684.1 COGs: COG1158 transcription termination factor; InterProIPR004665: IPR011129: IPR003593: IPR011112: IPR 011113: IPR000194; KEGG: sma:SAV_2915 transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; Rho termination factor domain protein; Rho termination factor RNA-binding; SMART: ATPase AAA; Cold shock protein; SPTR: transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: Rho termination factor, N-terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; Rho termination factor, RNA-binding domain; TIGRFAM: transcription termination factor Rho YP_004099685.1 COGs: COG0083 homoserine kinase; InterPro IPR000870: IPR006203: IPR006204: IPR013750; KEGG: cfl:Cfla_1057 homoserine kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: homoserine kinase; TIGRFAM: homoserine kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: homoserine kinase YP_004099686.1 COGs: COG0498 threonine synthase; InterPro IPR004450: IPR000634: IPR001926; KEGG: cfl:Cfla_1056 threonine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: threonine synthase; TIGRFAM: threonine synthase; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_004099687.1 COGs: COG0460 homoserine dehydrogenase; InterProIPR016204: IPR019811: IPR005106: IPR001342: IPR 002912; KEGG: kra:Krad_1252 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD binding domain; ACT domain YP_004099688.1 COGs: COG0019 diaminopimelate decarboxylase; InterPro IPR002986: IPR000183; KEGG: kfl:Kfla_5067 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: diaminopimelate decarboxylase; TIGRFAM: diaminopimelate decarboxylase; PFAM: pyridoxal-dependent decarboxylase, C-terminal sheet domain; pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_004099689.1 InterPro IPR008909; KEGG: mmi:MMAR_4105 arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain protein; SPTR: Arginyl tRNA synthetase; PFAM: DALR anticodon binding domain YP_004099690.1 KEGG: xce:Xcel_0926 hypothetical protein; SPTR: uncharacterized protein YP_004099691.1 KEGG: swi:Swit_4862 response regulator receiver protein; SPTR: Response regulator receiver protein YP_004099692.1 COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR004682: IPR018389; KEGG: cgt:cgR_2222 hypothetical protein; PFAM: extracellular solute-binding protein, family 7; SPTR: C4-dicarboxylate transporter C4-dicarboxylate-binding protein; TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family YP_004099693.1 COGs: COG3090 TRAP-type C4-dicarboxylate transporter small permease; InterPro IPR007387; KEGG: cef:CE2240 C4-dicarboxylate permease small protein; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; SPTR: C4-dicarboxylate permease small protein; PFAM: tripartite ATP-independent periplasmic transporters, DctQ component YP_004099694.1 COGs: COG1593 TRAP-type C4-dicarboxylate transporter large permease; InterPro IPR004681: IPR010656; KEGG: cef:CE2239 C4-dicarboxylate permease large protein; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: 2,3-diketo-l-gulonate trap transporter large permease yian; TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter DctM subunit YP_004099695.1 COGs: COG3004 Na+/H+ antiporter; InterPro IPR004670; KEGG: bcv:Bcav_1238 Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter NhaA; SPTR: Na+/H+ antiporter NhaA; TIGRFAM: Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter 1; TIGRFAM: Na+/H+ antiporter NhaA; TC 2.A.33.1.1 YP_004099696.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485: IPR018483; KEGG: kse:Ksed_11390 pentulose/hexulose kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: Pentulose/hexulose kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: gluconate kinase, FGGY type YP_004099697.1 COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669: IPR013131: IPR013118; KEGG: fre:Franean1_3198 mannitol dehydrogenase domain-containing protein; PFAM: mannitol dehydrogenase; Mannitol dehydrogenase rossman domain; SPTR: mannitol dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain YP_004099698.1 COGs: COG1904 glucuronate isomerase; InterPro IPR003766; KEGG: fre:Franean1_3197 glucuronate isomerase; PFAM: glucuronate isomerase; PRIAM: glucuronate isomerase; SPTR: glucuronate isomerase; PFAM: glucuronate isomerase YP_004099699.1 COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: fre:Franean1_3196 hypothetical protein; PFAM: protein of unknown function DUF2088; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088) YP_004099700.1 COGs: COG1609 transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: fre:Franean1_3256 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004099701.1 COGs: COG1609 transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: fre:Franean1_3256 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004099702.1 COGs: COG1472 beta-glucosidase-related glycosidase; InterPro IPR017909: IPR001764: IPR002772; KEGG: mmw:Mmwyl1_3059 xylan 1,4-beta-xylosidase; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Xylan 1,4-beta-xylosidase; PFAM: glycosyl hydrolase family 3 C terminal domain; glycosyl hydrolase family 3 N terminal domain YP_004099703.1 COGs: COG0362 6-phosphogluconate dehydrogenase; InterProIPR006113: IPR006183: IPR006115: IPR006114: IPR 006184; KEGG: sro:Sros_3959 6-phosphogluconate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase domain-containing protein; 6-phosphogluconate dehydrogenase NAD-binding; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating YP_004099704.1 COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232; KEGG: gob:Gobs_1558 hypothetical protein; SPTR: uncharacterized protein; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268 YP_004099705.1 COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: cef:CE2360 carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: phosphoribosylaminoimidazole carboxylase catalytic subunit; PFAM: AIR carboxylase YP_004099706.1 COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: gob:Gobs_1561 protein of unknown function DUF111; PFAM: protein of unknown function DUF111; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF111; TIGRFAM: conserved hypothetical protein TIGR00299 YP_004099707.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550; KEGG: kra:Krad_1235 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Hemolysin containing CBS domains protein; PFAM: CBS domain; Domain of unknown function DUF21 YP_004099708.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550: IPR005170; KEGG: kra:Krad_1234 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SPTR: Hemolysin containing CBS domains protein; PFAM: CBS domain; Domain of unknown function DUF21; transporter associated domain YP_004099709.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR003593; KEGG: kse:Ksed_18430 ABC-type multidrug transporter ATPase component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter ATPase component; PFAM: ABC transporter YP_004099710.1 KEGG: jde:Jden_1805 hypothetical protein; SPTR: ABC transporter membrane protein YP_004099711.1 COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterProIPR011603: IPR001078: IPR001017: IPR005475: IPR 000897; KEGG: kra:Krad_1228 alpha-ketoglutarate decarboxylase; PFAM: transketolase; dehydrogenase E1 component; catalytic domain-containing protein of components of various dehydrogenase complexes; SPTR: alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); dehydrogenase E1 component; transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component YP_004099712.1 KEGG: tbi:Tbis_2891 hypothetical protein; SPTR: uncharacterized protein YP_004099713.1 InterPro IPR001087; KEGG: kse:Ksed_18470 hypothetical protein; PFAM: lipolytic protein G-D-S-L family; SPTR: uncharacterized protein; PFAM: GDSL-like Lipase/acylhydrolase YP_004099714.1 KEGG: sco:SCO5242 integral membrane protein; SPTR: integral membrane protein YP_004099715.1 InterPro IPR003482; KEGG: ske:Sked_08450 transcription factor WhiB; PFAM: transcription factor WhiB; SPTR: uncharacterized protein; PFAM: transcription factor WhiB YP_004099716.1 COGs: COG3920 Signal transduction histidine kinase; InterProIPR005467: IPR003594: IPR004358: IPR013656: IPR 011495; KEGG: kra:Krad_3796 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; hypothetical protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: two-component system sensor kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase; PAS fold YP_004099717.1 COGs: COG2902 NAD-specific glutamate dehydrogenase; InterPro IPR007780; KEGG: bcv:Bcav_1575 NAD-glutamate dehydrogenase; PFAM: NAD-glutamate dehydrogenase; SPTR: uncharacterized protein; PFAM: Bacterial NAD-glutamate dehydrogenase YP_004099718.1 KEGG: mbr:MONBRDRAFT_12828 hypothetical protein; SPTR: uncharacterized protein YP_004099719.1 InterPro IPR019639; KEGG: kse:Ksed_08750 protein of unknown function (DUF2505); PFAM: protein of unknown function DUF2505; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2505) YP_004099720.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005931: IPR015590: IPR016160; KEGG: kse:Ksed_08740 delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; PFAM: aldehyde dehydrogenase; SPTR: delta-1-pyrroline-5-carboxylate dehydrogenase 1; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 YP_004099721.1 COGs: COG3296 conserved hypothetical protein; KEGG: mcu:HMPREF0573_11485 hypothetical protein; SPTR: uncharacterized protein YP_004099722.1 COGs: COG2755 lysophospholipase L1 and related esterase; InterPro IPR001087; KEGG: rer:RER_09500 hypothetical protein; PFAM: lipolytic protein G-D-S-L family; SPTR: Lipase/acylhydrolase family protein; PFAM: GDSL-like Lipase/acylhydrolase YP_004099723.1 InterPro IPR001647; KEGG: nca:Noca_1231 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family YP_004099724.1 KEGG: cfl:Cfla_2318 hypothetical protein; SPTR: uncharacterized protein YP_004099725.1 InterPro IPR014292: IPR004255; KEGG: sen:SACE_6439 hypothetical protein; PFAM: protein of unknown function UPF0089; SPTR: uncharacterized protein; TIGRFAM: acyltransferase, WS/DGAT/MGAT; PFAM: protein of unknown function (DUF1298); Uncharacterised protein family (UPF0089); TIGRFAM: acyltransferase, WS/DGAT/MGAT YP_004099726.1 KEGG: sro:Sros_2595 hypothetical protein; SPTR: uncharacterized protein YP_004099727.1 KEGG: kfl:Kfla_1655 hypothetical protein; SPTR: uncharacterized protein YP_004099728.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: gob:Gobs_4271 hypothetical protein; SPTR: regulator; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004099729.1 InterPro IPR013974; KEGG: cfl:Cfla_2320 hypothetical protein; PFAM: SAF domain protein; SPTR: uncharacterized protein YP_004099730.1 InterPro IPR010093; KEGG: kfl:Kfla_1648 DNA binding domain protein, excisionase family; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family YP_004099731.1 KEGG: gob:Gobs_4274 hypothetical protein; SPTR: uncharacterized protein YP_004099732.1 InterPro IPR018392; KEGG: cfl:Cfla_2323 peptidoglycan-binding lysin domain protein; PFAM: peptidoglycan-binding lysin domain; SPTR: uncharacterized protein; PFAM: LysM domain YP_004099733.1 KEGG: kse:Ksed_08670 hypothetical protein; SPTR: uncharacterized protein YP_004099734.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); InterProIPR014018: IPR000185: IPR011115: IPR011130: IPR 011116: IPR020937; KEGG: cfl:Cfla_2325 preprotein translocase, Secsubunit alpha; PFAM: SecA DEAD domain protein; SecA preprotein cross-linking region; SecA Wing and Scaffold; SPTR: translocase; TIGRFAM: preprotein translocase, SecA subunit; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, Secsubunit alpha YP_004099735.1 COGs: COG3214 conserved hypothetical protein; InterPro IPR009351; KEGG: kse:Ksed_08640 hypothetical protein; PFAM: protein of unknown function DUF1006; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1006) YP_004099736.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sro:Sros_1417 response regulator receiver protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004099737.1 COGs: COG1544 ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: kra:Krad_3811 sigma 54 modulation protein/ribosomal protein S30EA; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; SPTR: uncharacterized protein; TIGRFAM: ribosomal subunit interface protein; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_004099738.1 COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: gob:Gobs_4282 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: phosphoribosyltransferase; manually curated; PFAM: phosphoribosyl transferase domain YP_004099739.1 InterPro IPR019606: IPR018910; KEGG: kse:Ksed_08610 lipoprotein LpqB family protein/sporulation and spore germination protein; PFAM: Lipoprotein LpqB, GerMN domain; Lipoprotein LpqB, beta-propeller domain-like; SPTR: Lipoprotein LpqB family protein/sporulation and spore germination protein; PFAM: Lipoprotein LpqB beta-propeller domain; sporulation and spore germination YP_004099740.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR003660: IPR003661: IPR003594: IPR 004358; KEGG: kra:Krad_3814 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: two-component system histidine kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004099741.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867: IPR005829; KEGG: scb:SCAB_55281 two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004099742.1 KEGG: cag:Cagg_0021 WD40 domain protein beta propeller; SPTR: uncharacterized protein YP_004099743.1 COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR015878: IPR020082; KEGG: aau:AAur_1316 S-adenosyl-L-homocysteine hydrolase; PFAM: S-adenosyl-L-homocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase, NAD binding; PRIAM: adenosylhomocysteinase; SPTR: adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase YP_004099744.1 COGs: COG2354 conserved hypothetical protein; InterPro IPR008526; KEGG: cfl:Cfla_2445 protein of unknown function DUF808; PFAM: protein of unknown function DUF808; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF808) YP_004099745.1 InterPro IPR019490: IPR006162; KEGG: kra:Krad_3839 RpiR family transcriptional regulator; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; SPTR: uncharacterized protein; PFAM: Bacterial phospho-glucose isomerase C-terminal region YP_004099746.1 InterPro IPR005651; KEGG: ske:Sked_09130 hypothetical protein; PFAM: protein of unknown function DUF343; SPTR: uncharacterized protein; PFAM: Trm112p-like protein YP_004099747.1 COGs: COG1109 phosphomannomutase; InterProIPR005841: IPR005844: IPR005845: IPR005846: IPR 005843; KEGG: kra:Krad_3841 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004099748.1 KEGG: sen:SACE_6461 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3499) YP_004099749.1 KEGG: kra:Krad_3844 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: Domain of unknown function (DUF1025) YP_004099750.1 KEGG: bcv:Bcav_1208 hypothetical protein; SPTR: secreted protein YP_004099751.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: rsa:RSal33209_3016 glycosyltransferase; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase family 2 YP_004099752.1 InterPro IPR003482; KEGG: kfl:Kfla_1589 transcription factor WhiB; PFAM: transcription factor WhiB; SPTR: WhiB-family transcriptional regulator, WhiB protein; PFAM: transcription factor WhiB YP_004099753.1 COGs: COG0391 conserved hypothetical protein; InterPro IPR010115: IPR002882; KEGG: kra:Krad_3851 LPPG:FO 2-phospho-L-lactate transferase; PFAM: protein of unknown function UPF0052 and CofD; SPTR: LPPG:Fo 2-phospho-L-lactate transferase; TIGRFAM: LPPG domain protein containing protein; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: LPPG:FO 2-phospho-L-lactate transferase YP_004099754.1 COGs: COG1478 conserved hypothetical protein; InterPro IPR008225: IPR002847; KEGG: kra:Krad_3852 F420-dependent oxidoreductase, PFAM: protein of unknown function DUF129; SPTR: uncharacterized protein; TIGRFAM: F420-dependent oxidoreductase; PFAM: F420-0:gamma-glutamyl ligase; TIGRFAM: F420-0:gamma-glutamyl ligase YP_004099755.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149; KEGG: kfl:Kfla_5193 alcohol dehydrogenase zinc-binding domain protein; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004099756.1 COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302: IPR005829: IPR015884; KEGG: fre:Franean1_0980 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: malate oxidoreductase; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_004099757.1 COGs: COG2206 HD-GYP domain; InterPro IPR003607; KEGG: tfu:Tfu_0551 lipoprotein; SMART: metal-dependent phosphohydrolase HD region; SPTR: lipoprotein YP_004099758.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006674; KEGG: tbi:Tbis_2919 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: HDIG domain protein; PFAM: HD domain YP_004099760.1 InterPro IPR014295; KEGG: ace:Acel_0539 anti-sigma factor; SPTR: anti-sigma factor; TIGRFAM: anti-sigma factor; TIGRFAM: anti-sigma factor, TIGR02949 family YP_004099761.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014293: IPR014284: IPR007627: IPR013249; KEGG: art:Arth_2651 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, TIGR02947 family YP_004099762.1 COGs: COG3571 hydrolase of the alpha/beta-hydrolase fold; KEGG: gob:Gobs_4921 hypothetical protein; SPTR: uncharacterized protein YP_004099763.1 COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: kse:Ksed_14680 hypothetical protein; PFAM: protein of unknown function DUF159; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, COG2135 YP_004099764.1 InterPro IPR011637; KEGG: rha:RHA1_ro00971 hypothetical protein; PFAM: DoxX family protein; SPTR: uncharacterized protein; PFAM: DoxX YP_004099765.1 COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; InterPro IPR006264: IPR016228: IPR001986; KEGG: kra:Krad_1209 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); PRIAM: 3-phosphoshikimate 1-carboxyvinyltransferase; SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; manually curated; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase YP_004099766.1 COGs: COG1162 GTPase; InterPro IPR010914: IPR004881; KEGG: bcv:Bcav_1262 GTPase EngC; PFAM: GTPase EngC; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A YP_004099767.1 InterPro IPR000361; KEGG: xce:Xcel_0286 HesB/YadR/YfhF-family protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: HesB/YadR/YfhF-family protein; PFAM: Iron-sulphur cluster biosynthesis YP_004099768.1 COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR011809: IPR000760: IPR020583; KEGG: aau:AAur_2645 histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; SPTR: inositol monophosphatase; TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase family; TIGRFAM: histidinol-phosphate phosphatase HisN, inositol monophosphatase family YP_004099769.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863; KEGG: kse:Ksed_19020 predicted Zn-dependent peptidase; PFAM: peptidase M16 domain protein; SPTR: protease; PFAM: peptidase M16 inactive domain; Insulinase (peptidase family M16) YP_004099770.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863; KEGG: kfl:Kfla_5236 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: Zinc protease; PFAM: peptidase M16 inactive domain; Insulinase (peptidase family M16) YP_004099771.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: tpr:Tpau_3637 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V YP_004099772.1 COGs: COG1615 conserved hypothetical protein; InterPro IPR005372; KEGG: cfl:Cfla_2461 protein of unknown function UPF0182; PFAM: protein of unknown function UPF0182; SPTR: UPF0182 protein JNB_07314; PFAM: Uncharacterised protein family (UPF0182) YP_004099773.1 KEGG: cfl:Cfla_2462 hypothetical protein; SPTR: uncharacterized protein YP_004099774.1 COGs: COG3480 secreted protein containing a PDZ domain; InterPro IPR001478; KEGG: sro:Sros_8344 hypothetical protein; SPTR: secreted protein; PFAM: Lon protease (S16) C-terminal proteolytic domain YP_004099775.1 COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: scb:SCAB_30561 MoaE-like protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin biosynthesis protein E; PFAM: MoaE protein YP_004099776.1 COGs: COG5282 conserved hypothetical protein; InterPro IPR018766; KEGG: kse:Ksed_19090 hypothetical protein; PFAM: protein of unknown function DUF2342; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterised conserved protein (DUF2342); TIGRFAM: hydrolase YP_004099777.1 InterPro IPR000086; KEGG: nca:Noca_1524 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004099778.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: bcv:Bcav_2891 protein of unknown function DUF45; PFAM: protein of unknown function DUF45; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF45 YP_004099779.1 KEGG: pfr:PFREUD_09900 hypothetical protein; SPTR: uncharacterized protein YP_004099780.1 KEGG: cms:CMS_1890 hypothetical protein; SPTR: uncharacterized protein YP_004099781.1 COGs: COG0661 unusual protein kinase; InterPro IPR000719: IPR004147: IPR002575; KEGG: kfl:Kfla_5331 ABC transporter; PFAM: ABC transporter; aminoglycoside phosphotransferase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC1 family YP_004099782.1 KEGG: kfl:Kfla_5332 hypothetical protein; SPTR: uncharacterized protein YP_004099784.1 InterPro IPR003482: IPR017956: IPR000637; KEGG: kra:Krad_1181 transcription factor WhiB; PFAM: transcription factor WhiB; AT hook, DNA-binding motif; SPTR: WhiB-family transcriptional regulator; PFAM: transcription factor WhiB; AT hook motif YP_004099785.1 KEGG: krh:KRH_14310 acetate--CoA ligase; SPTR: GfdT protein YP_004099786.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121: IPR014016: IPR014017: IPR000212; KEGG: kra:Krad_1179 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: ATP-dependent DNA helicase; manually curated; PFAM: HRDC domain; UvrD/REP helicase YP_004099787.1 COGs: COG0695 glutaredoxin and related protein; InterPro IPR002109: IPR011915: IPR017937; KEGG: bcv:Bcav_2898 glutaredoxin-like protein; PFAM: glutaredoxin; SPTR: glutaredoxin-like protein; TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; TIGRFAM: glutaredoxin-like protein YP_004099788.1 COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375: IPR015376: IPR000086: IPR020084; KEGG: tbi:Tbis_2968 NAD(+) diphosphatase; PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; PRIAM: NAD(+) diphosphatase; SPTR: NADH pyrophosphatase; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NADH pyrophosphatase-like rudimentary NUDIX domain YP_004099789.1 COGs: COG3173 aminoglycoside phosphotransferase; InterPro IPR002575; KEGG: kra:Krad_1175 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: Macrolide 2'-phosphotransferase; PFAM: phosphotransferase enzyme family YP_004099790.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212; KEGG: kra:Krad_1172 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: DNA helicase; PFAM: UvrD/REP helicase YP_004099791.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212; KEGG: kra:Krad_1171 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase; PFAM: UvrD/REP helicase YP_004099792.1 COGs: COG3695 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048: IPR004360; KEGG: cfl:Cfla_0254 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain YP_004099793.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR000594: IPR007901; KEGG: ace:Acel_1777 molybdopterin biosynthesis-like protein MoeZ; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; rhodanese; SMART: rhodanese; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family YP_004099794.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: sgr:SGR_2355 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: tetR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004099795.1 KEGG: ske:Sked_27680 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3107) YP_004099796.1 KEGG: tbi:Tbis_1729 hypothetical protein; SPTR: uncharacterized protein YP_004099797.1 KEGG: kfl:Kfla_5362 hypothetical protein; SPTR: uncharacterized protein YP_004099798.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021: IPR001650: IPR014014: IPR014001: IPR 011545: IPR000629; KEGG: ske:Sked_27750 DNA/RNA helicase, superfamily II; PFAM: DEAD/DEAH box helicase; helicase; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004099799.1 COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: nca:Noca_1467 cobyrinic acid a,c-diamide synthase; SPTR: Possible soj/para-related protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004099800.1 KEGG: sna:Snas_3837 hypothetical protein; SPTR: uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain YP_004099801.1 InterPro IPR000276; KEGG: fal:FRAAL6067 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2800) YP_004099802.1 KEGG: bcv:Bcav_2908 multiple antibiotic resistance (MarC)-related protein protein; SPTR: MarC family multiple antibiotic resistance transporter YP_004099803.1 COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR003141: IPR004013; KEGG: xce:Xcel_0771 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: uncharacterized protein; PFAM: PHP domain YP_004099804.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014325: IPR014284: IPR007627: IPR013249; KEGG: cfl:Cfla_2179 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_004099805.1 KEGG: azl:AZL_e00660 filamentous haemagglutinin outer membrane protein; SPTR: uncharacterized protein YP_004099806.1 KEGG: rha:RHA1_ro05202 hypothetical protein; SPTR: uncharacterized protein YP_004099807.1 COGs: COG2030 acyl dehydratase; InterPro IPR002539; KEGG: nca:Noca_1459 dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: MaoC domain protein dehydratase; PFAM: MaoC like domain YP_004099808.1 COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: kse:Ksed_19250 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: Uncharacterized conserved protein; PFAM: protein of unknown function (DUF1212) YP_004099809.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR007865: IPR000994: IPR001131; KEGG: saq:Sare_0543 peptidase M24; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: Aminopeptidase P; PFAM: Aminopeptidase P, N-terminal domain; metallopeptidase family M24 YP_004099810.1 KEGG: nca:Noca_4334 hypothetical protein; SPTR: uncharacterized protein YP_004099811.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: kfl:Kfla_5397 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004099812.1 KEGG: tpr:Tpau_4160 pentapeptide repeat-containing protein; SPTR: Pentapeptide repeat-containing protein; PFAM: protein of unknown function (DUF664) YP_004099813.1 InterPro IPR003477; KEGG: kfl:Kfla_2916 transcriptional modulator of MazE/toxin, MazF; PFAM: PemK family protein; SPTR: transcriptional modulator of MazE/toxin, MazF; PFAM: PemK-like protein YP_004099814.1 InterPro IPR011600; KEGG: art:Arth_2725 peptidase C14, caspase catalytic subunit P20; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: peptidase C14, caspase catalytic subunit p20; PFAM: Caspase domain YP_004099815.1 KEGG: scb:SCAB_33261 hypothetical protein; SPTR: uncharacterized protein YP_004099816.1 InterPro IPR006311; KEGG: sru:SRU_2417 hypothetical protein; SPTR: uncharacterized protein; PFAM: Extensin-like protein C-terminus YP_004099817.1 COGs: COG0686 alanine dehydrogenase; InterPro IPR007698; KEGG: cai:Caci_7427 alanine dehydrogenase/PNT domain protein; PFAM: alanine dehydrogenase/PNT domain protein; SPTR: alanine dehydrogenase/PNT domain protein; PFAM: alanine dehydrogenase/PNT, C-terminal domain; alanine dehydrogenase/PNT, N-terminal domain YP_004099818.1 COGs: COG2301 citrate lyase subunit beta; InterPro IPR011206: IPR005000; KEGG: amd:AMED_0078 citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase; PRIAM: Citryl-CoA lyase; SPTR: citrate lyase beta chain; PFAM: HpcH/HpaI aldolase/citrate lyase family YP_004099819.1 COGs: COG2301 citrate lyase subunit beta; InterPro IPR011206: IPR005000; KEGG: amd:AMED_0079 citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase; SPTR: citrate lyase subunit beta, ; PFAM: HpcH/HpaI aldolase/citrate lyase family YP_004099820.1 KEGG: tcu:Tcur_1191 hypothetical protein; SPTR: uncharacterized protein YP_004099821.1 COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR000644: IPR006668; KEGG: xce:Xcel_0766 MgtE intracellular region; PFAM: MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: magnesium (Mg2+) transporter; PFAM: MgtE intracellular N domain; CBS domain; PRC-barrel domain YP_004099822.1 COGs: COG4420 membrane protein; InterPro IPR010406; KEGG: sma:SAV_3111 hypothetical protein; PFAM: protein of unknown function DUF1003; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1003) YP_004099823.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR002744: IPR019591: IPR000808; KEGG: kse:Ksed_19390 chromosome partitioning ATPase; PFAM: ATPase-like, ParA/MinD; protein of unknown function DUF59; SPTR: ATP-binding protein; PFAM: ParA/MinD ATPase like; Domain of unknown function DUF59; ATPase MipZ YP_004099824.1 InterPro IPR018448: IPR003998; KEGG: rsa:RSal33209_1193 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase TatB YP_004099825.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940: IPR001254; KEGG: bcv:Bcav_2919 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; SPTR: protease; PFAM: Trypsin YP_004099826.1 KEGG: ssl:SS1G_03268 hypothetical protein; SPTR: Predicted protein YP_004099827.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: tbi:Tbis_3014 ECF subfamily RNA polymerase sigma-24; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004099828.1 COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: cfl:Cfla_1005 O-methyltransferase family 3; PFAM: O-methyltransferase family 3; SPTR: Probable methyltransferase; PFAM: O-methyltransferase YP_004099829.1 KEGG: mav:MAV_1356 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3117) YP_004099830.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753: IPR018376; KEGG: kfl:Kfla_5504 enoyl-CoA hydratase/isomerase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase/isomerase; manually curated; PFAM: enoyl-CoA hydratase/isomerase family YP_004099831.1 KEGG: kra:Krad_1147 integral membrane protein; SPTR: integral membrane protein YP_004099832.1 InterPro IPR019933; KEGG: kra:Krad_1145 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DivIVA domain; TIGRFAM: DivIVA domain YP_004099833.1 COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: kfl:Kfla_5508 hypothetical protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: uncharacterized protein; PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 1; conserved hypothetical protein, DprA/Smf-related, family 2 YP_004099834.1 COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010174: IPR002933: IPR011650; KEGG: kra:Krad_1143 succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Succinyl-diaminopimelate desuccinylase; TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: succinyl-diaminopimelate desuccinylase YP_004099835.1 COGs: COG2171 Tetrahydrodipicolinate N-succinyltransferase; InterPro IPR019875; KEGG: kfl:Kfla_5521 2,3,4, 5-tetrahydropyridine-2-carboxylate N-succinyltransferase; SPTR: Probable transferase; TIGRFAM:2,3,4,5-tetrahydropyridine-2,6-dicarboxylat eN-succinyltransferase; TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_004099836.1 KEGG: art:Arth_2807 hypothetical protein; SPTR: Conserved protein, lipoprotein YP_004099837.1 KEGG: kfl:Kfla_1437 hypothetical protein; SPTR: uncharacterized protein YP_004099838.1 COGs: COG0372 citrate synthase; InterPro IPR010953: IPR002020: IPR019810; KEGG: rsa:RSal33209_1176 citrate synthase; PFAM: citrate synthase; PRIAM: citrate (Si)-synthase; SPTR: citrate synthase; TIGRFAM: citrate synthase I; PFAM: citrate synthase; TIGRFAM: citrate synthase I (hexameric type) YP_004099839.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR019880: IPR004839: IPR004838; KEGG: tcu:Tcur_1150 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; TIGRFAM: succinyldiaminopimelate transaminase; PFAM: Aminotransferase class I and II; TIGRFAM: succinyldiaminopimelate transaminase YP_004099840.1 InterPro IPR017896: IPR000813: IPR017900; KEGG: xce:Xcel_0970 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain YP_004099841.1 InterPro IPR000182; KEGG: kra:Krad_1137 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004099842.1 COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: nca:Noca_1161 von Willebrand factor A; PFAM: von Willebrand factor A; SPTR: uncharacterized protein; PFAM: peptidoglycan binding domain; VanW like protein YP_004099843.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR017810: IPR003737; KEGG: sma:SAV_3138 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; PFAM: LmbE family protein; SPTR: N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; TIGRFAM:1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D -glucopyranosidedeacetylase; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase YP_004099844.1 COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: nca:Noca_2400 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004099845.1 COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225: IPR006298: IPR000795: IPR004161: IPR 000640; KEGG: sro:Sros_7974 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Small GTP-binding protein domain:GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_004099846.1 InterPro IPR020476: IPR000086: IPR020084; KEGG: xce:Xcel_0048 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: mutT-like protein; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein YP_004099847.1 COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: kse:Ksed_19540 ABC-type dipeptide transporter periplasmic component; PFAM: extracellular solute-binding protein family 5; SPTR: oligopeptide/dipeptide ABC transporter peptide-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004099848.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: kse:Ksed_19550 ABC-type dipeptide/oligopeptide/nickel transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Dipeptide transporter permease dppB; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099849.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: ami:Amir_0208 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Probable ABC-transporter inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099850.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR003439: IPR003593: IPR010066: IPR013563: IPR 017871; KEGG: ami:Amir_0209 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004099851.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR003439: IPR003593: IPR010066: IPR013563: IPR 017871; KEGG: ami:Amir_0210 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004099852.1 InterPro IPR017909: IPR006311; KEGG: kse:Ksed_18940 hypothetical protein; SPTR: uncharacterized protein YP_004099853.1 KEGG: gem:GM21_0462 tetratricopeptide TPR_2 repeat protein; SPTR: uncharacterized protein YP_004099854.1 KEGG: rmu:RMDY18_15750 dioxygenase related to 2-nitropropane dioxygenase; SPTR: uncharacterized protein YP_004099855.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR020904; KEGG: cef:CE0380 GDP-D-mannose dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: GDP-D-mannose dehydratase; PFAM: NAD dependent epimerase/dehydratase family YP_004099856.1 InterPro IPR007016; KEGG: scb:SCAB_83101 hypothetical protein; PFAM: O-antigen polymerase; SPTR: uncharacterized protein; PFAM: O-antigen ligase YP_004099857.1 InterPro IPR000182; KEGG: gfo:GFO_2001 hypothetical protein; SPTR: uncharacterized protein YP_004099858.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: tma:TM0622 lipopolysaccharide biosynthesis protein, PFAM: glycosyl transferase group 1; SPTR: Lipopolysaccharide biosynthesis protein; PFAM: glycosyl transferases group 1 YP_004099859.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: hau:Haur_1595 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase family protein; PFAM: polysaccharide deacetylase YP_004099860.1 KEGG: avn:Avin_30030 hypothetical protein; SPTR: uncharacterized protein YP_004099861.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR003856; KEGG: cfl:Cfla_0897 capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family YP_004099862.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: rca:Rcas_1346 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: galactosyltransferase; PFAM: glycosyl transferases group 1 YP_004099863.1 COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterPro IPR003439: IPR017940: IPR003593: IPR017871; KEGG: mrd:Mrad2831_5367 lipid ABC transporter ATPase/inner membrane protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding/permease; PFAM: ABC transporter YP_004099864.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: rme:Rmet_2719 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase, group 1 (Probably involved in lipopolysaccharide biosynthesis); PFAM: glycosyl transferases group 1 YP_004099865.1 KEGG: amd:AMED_8614 beta-glucosidase; SPTR: uncharacterized protein YP_004099866.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: prw:PsycPRwf_0244 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase, group 1 family; manually curated; PFAM: glycosyl transferases group 1 YP_004099867.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: amr:AM1_1023 glycosyl transferase, group 2 family protein; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase family 2; PFAM: glycosyl transferase family 2 YP_004099868.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: svi:Svir_01560 predicted PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Predicted PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_004099869.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025: IPR003869; KEGG: kfl:Kfla_0497 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD; SPTR: polysaccharide biosynthesis protein CapD; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; PFAM: polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase YP_004099870.1 COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: sro:Sros_1198 acylneuraminate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; SPTR: acylneuraminate cytidylyltransferase; PFAM: Cytidylyltransferase YP_004099871.1 COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR000182; KEGG: kfl:Kfla_0500 spore coat polysaccharide biosynthesis protein predicted glycosyltransferase-like protein; SPTR: Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase-like protein YP_004099872.1 COGs: COG2089 Sialic acid synthase; InterPro IPR006190: IPR020030: IPR013132: IPR013974; KEGG: sro:Sros_1204 N-acylneuraminate-9-phosphate synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: N-acylneuraminate-9-phosphate synthase; TIGRFAM: pseudaminic acid synthase; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase YP_004099873.1 InterPro IPR001584; KEGG: cjk:jk1356 transposase for IS3514b; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004099874.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: cgb:cg0419 glycosyltransferase; PFAM: sugar transferase; SPTR: glycosyltransferase; PFAM: Bacterial sugar transferase YP_004099875.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: cgb:cg0418 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_004099876.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: bbr:BB0876 polysaccharide biosynthesis protein; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: lipopolysaccharide biosynthesis protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004099877.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: rhi:NGR_c19670 probable lipopolysaccharide modification acyltransferase; PFAM: acyltransferase 3; SPTR: Probable lipopolysaccharide modification acyltransferase; manually curated; PFAM: acyltransferase family YP_004099878.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: rsa:RSal33209_1438 UDP-D-quinovosamine 4-dehydrogenase; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Probable dtdp-glucose 4,6-dehydratase transmembrane protein; PFAM: polysaccharide biosynthesis protein YP_004099879.1 KEGG: scl:sce6047 protein kinase YP_004099880.1 COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: nfa:nfa24980 transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: transcriptional regulator; PFAM: HxlR-like helix-turn-helix YP_004099881.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: rha:RHA1_ro02392 methyltransferase; PFAM: methyltransferase type 11; SPTR: methyltransferase; PFAM: methyltransferase domain YP_004099882.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: nml:Namu_1402 alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold YP_004099883.1 InterPro IPR009959; KEGG: cyc:PCC7424_4712 protein of unknown function DUF1486; PFAM: protein of unknown function DUF1486; SPTR: uncharacterized protein; PFAM: SnoaL-like polyketide cyclase; TIGRFAM: conserved hypothetical protein, steroid delta-isomerase-related YP_004099884.1 KEGG: nca:Noca_2868 hypothetical protein; SPTR: uncharacterized protein YP_004099885.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR000719: IPR020635: IPR002290: IPR017442: IPR 017441: IPR008271; KEGG: nfa:nfa31920 serine/threonine protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: serine/threonine protein kinase; PFAM: protein kinase domain YP_004099886.1 InterPro IPR001845; KEGG: cfl:Cfla_0422 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004099887.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mjl:Mjls_3905 hypothetical protein; PFAM: cation efflux protein; SPTR: integral membrane protein; PFAM: Cation efflux family YP_004099888.1 COGs: COG1230 Co/Zn/Cd efflux system component; InterPro IPR002524; KEGG: sro:Sros_4981 CDF family cobalt/cadmium/zinc transporter; PFAM: cation efflux protein; SPTR: CDF family cobalt/cadmium/zinc transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004099889.1 InterPro IPR000601; KEGG: rba:RB10423 cycloinulo-oligosaccharide fructanotransferase; PFAM: PKD domain containing protein; SPTR: Probable cycloinulo-oligosaccharide fructanotransferase YP_004099890.1 KEGG: nca:Noca_4524 hypothetical protein; SPTR: uncharacterized protein; PFAM: BNR/Asp-box repeat YP_004099891.1 COGs: COG3211 phosphatase; InterPro IPR008557; KEGG: tbd:Tbd_1423 phosphatase; PFAM: protein of unknown function DUF839; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF839) YP_004099892.1 KEGG: nca:Noca_1110 hypothetical protein; SPTR: uncharacterized protein YP_004099893.1 KEGG: bph:Bphy_5182 hypothetical protein; SPTR: uncharacterized protein YP_004099894.1 COGs: COG3899 ATPase; InterPro IPR000792; KEGG: vap:Vapar_3549 LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: uncharacterized protein; PFAM: Archaeal ATPase; Bacterial regulatory proteins, luxR family YP_004099895.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR012951: IPR006093; KEGG: gob:Gobs_3657 FAD linked oxidase domain protein; PFAM: FAD linked oxidase; Berberine/berberine domain protein; SPTR: FAD linked oxidase; PFAM: Berberine and berberine like; FAD binding domain YP_004099896.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: art:Arth_4530 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter YP_004099897.1 InterPro IPR006162; KEGG: art:Arth_4529 hypothetical protein; SPTR: uncharacterized protein YP_004099898.1 KEGG: art:Arth_4528 ABC-type transporter involved in multi-copper enzyme maturation permease-like protein; SPTR: uncharacterized protein YP_004099899.1 KEGG: art:Arth_4527 hypothetical protein; SPTR: uncharacterized protein YP_004099900.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: mta:Moth_1478 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: transcriptional regulator protein; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004099901.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: sti:Sthe_0750 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Two-component sensor histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004099902.1 KEGG: bfu:BC1G_03511 hypothetical protein; SPTR: Amino acid adenylation domain protein YP_004099903.1 KEGG: mbo:Mb1610c phiRv1 phage protein; SPTR: uncharacterized protein YP_004099904.1 KEGG: vvi:100260681 hypothetical protein LOC100260681; SPTR: Ubiquitin carboxyl-terminal hydrolase YP_004099905.1 KEGG: rsq:Rsph17025_0443 hypothetical protein; SPTR: uncharacterized protein YP_004099906.1 COGs: COG3378 ATPase; InterPro IPR014015: IPR006500: IPR014818; KEGG: mra:MRA_1593 phiRv1 phage protein; PFAM: primase P4; SPTR: Probable phiRv1 phage protein; TIGRFAM: phage/plasmid primase, P4 family; PFAM: Poxvirus D5 protein-like; D5 N terminal like; TIGRFAM: phage/plasmid primase, P4 family, C-terminal domain YP_004099907.1 InterPro IPR003482; KEGG: gbr:Gbro_3493 transcription factor WhiB; PFAM: transcription factor WhiB; SPTR: transcription factor WhiB; PFAM: transcription factor WhiB YP_004099908.1 KEGG: bhy:BHWA1_00392 outer membrane receptor; SPTR: outer membrane receptor YP_004099909.1 KEGG: ele:Elen_1336 protein of unknown function DUF512; SPTR: uncharacterized protein YP_004099910.1 KEGG: sjp:SJA_C1-15750 metallophosphoesterase; SPTR: metallophosphoesterase YP_004099911.1 COGs: COG4653 phage phi-C31 gp36 major capsid-like protein; KEGG: scb:SCAB_48241 phage capsid protein; SPTR: Gp7; PFAM: Phage capsid family YP_004099912.1 SPTR: uncharacterized protein YP_004099913.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR004396: IPR006073: IPR002917: IPR013029; KEGG: kse:Ksed_20210 GTP-dependent nucleic acid-binding protein EngD; PFAM: protein of unknown function DUF933; GTP-binding protein HSR1-related; SPTR: GTP-binding protein; TIGRFAM: GTP-binding protein YchF; PFAM: GTPase of unknown function; protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF YP_004099914.1 COGs: COG1946 acyl-CoA thioesterase; KEGG: sgr:SGR_2035 hypothetical protein; SPTR: uncharacterized protein YP_004099915.1 COGs: COG1322 conserved hypothetical protein; InterPro IPR003798; KEGG: kse:Ksed_20260 hypothetical protein; PFAM: protein of unknown function DUF195; SPTR: DNA recombination protein RmuC-like; PFAM: RmuC family YP_004099916.1 InterPro IPR002035; KEGG: amd:AMED_7539 hypothetical protein; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: von Willebrand factor A YP_004099917.1 InterPro IPR002035; KEGG: kfl:Kfla_1855 von Willebrand factor A; SPTR: von Willebrand factor A YP_004099918.1 COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: kfl:Kfla_5577 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) YP_004099919.1 COGs: COG1570 exonuclease VII large subunit; InterPro IPR003753: IPR004365: IPR020579; KEGG: ske:Sked_26430 exodeoxyribonuclease VII large subunit; PFAM: exonuclease VII, large subunit-like; nucleic acid binding OB-fold tRNA/helicase-type; SPTR: exodeoxyribonuclease 7 large subunit; TIGRFAM: exodeoxyribonuclease VII large subunit; PFAM: exonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII large subunit YP_004099920.1 InterPro IPR003761; KEGG: kse:Ksed_20420 exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; SPTR: exodeoxyribonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII small subunit YP_004099921.1 KEGG: kra:Krad_1120 hypothetical protein; SPTR: secreted protein YP_004099922.1 COGs: COG1494 fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: kfl:Kfla_5587 fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; PRIAM: fructose-bisphosphatase; SPTR: fructose-1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II YP_004099923.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: tpr:Tpau_0525 PfkB domain protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004099924.1 InterPro IPR002035; KEGG: kfl:Kfla_1855 von Willebrand factor A; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: von Willebrand factor A; PFAM: von Willebrand factor A domain YP_004099925.1 COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: bfa:Bfae_26130 ABC-type sugar transport system, periplasmic component; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transporter periplasmic component; PFAM: Bacterial extracellular solute-binding protein YP_004099926.1 COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: bfa:Bfae_26140 permease of ABC-type sugar transporter; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Permease component of ABC-type sugar transporter; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099927.1 COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: bfa:Bfae_26150 ABC-type sugar transport system, permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type sugar transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004099928.1 COGs: COG1951 Tartrate dehydratase subunit alpha/fumarate hydratase class I N-terminal domain; InterPro IPR011167: IPR004647: IPR004646: IPR020557; KEGG: rop:ROP_59610 fumarate hydratase class I; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; Fe-S type hydro-lyase tartrate/fumarate alpha region; SPTR: fumarate hydratase class I; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta; PFAM: Fumarase C-terminus; fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region YP_004099929.1 COGs: COG0288 carbonic anhydrase; InterPro IPR001765; KEGG: nca:Noca_2952 carbonic anhydrase; PFAM: carbonic anhydrase; SPTR: carbonic anhydrase, ; PFAM: carbonic anhydrase YP_004099930.1 COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: cms:CMS_1502 oligopeptidase; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; PRIAM: peptidyl-dipeptidase Dcp; SPTR: peptidyl-dipeptidase; PFAM: peptidase family M3 YP_004099931.1 KEGG: sen:SACE_4488 hypothetical protein; SPTR: uncharacterized protein; PFAM: DNA/RNA tunnel of bacterial DNA dependent RNA polymerase YP_004099932.1 InterPro IPR009324; KEGG: nca:Noca_0876 hypothetical protein; PFAM: protein of unknown function DUF981; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF981) YP_004099933.1 InterPro IPR005500; KEGG: tbi:Tbis_0208 hypothetical protein; PFAM: protein of unknown function DUF309; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF309) YP_004099934.1 COGs: COG1109 phosphomannomutase; InterProIPR006352: IPR005841: IPR005844: IPR005845: IPR 005846: IPR005843; KEGG: sgr:SGR_2800 phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: phosphoglucosamine mutase; TIGRFAM: phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase YP_004099935.1 COGs: COG0103 ribosomal protein S9; InterPro IPR000754: IPR020574; KEGG: krh:KRH_06470 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: ribosomal protein S9/S16 YP_004099936.1 COGs: COG0102 ribosomal protein L13; InterPro IPR005822: IPR005823; KEGG: krh:KRH_06460 50S ribosomal protein L13; PFAM: ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: ribosomal protein L13; manually curated; PFAM: ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type YP_004099937.1 InterPro IPR001845; KEGG: xce:Xcel_0321 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: ArsR-family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004099938.1 InterPro IPR011701: IPR005829; KEGG: xce:Xcel_0322 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004099939.1 InterPro IPR022272; KEGG: hoh:Hoch_2240 hypothetical protein; SPTR: uncharacterized protein YP_004099940.1 KEGG: rer:pREL1_0231 hypothetical protein; SPTR: Conserved hypothetical membrane protein YP_004099941.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: kfl:Kfla_3500 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family YP_004099942.1 COGs: COG1523 type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR006589: IPR011839: IPR006047: IPR004193; KEGG: kfl:Kfla_2775 alpha-1,6-glucosidase, pullulanase-type; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: alpha-1,6-glucosidase, pullulanase-type; TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: Domain of unknown function (DUF3372); alpha amylase, catalytic domain; carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: alpha-1,6-glucosidases, pullulanase-type YP_004099943.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: kse:Ksed_02710 hypothetical protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: Uncharacterized conserved protein; PFAM: YbaK / prolyl-tRNA synthetases associated domain YP_004099944.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136: IPR001295; KEGG: rha:RHA1_ro00808 2-nitropropane dioxygenase; PFAM: 2-nitropropane dioxygenase NPD; PRIAM: 2-nitropropane dioxygenase; SPTR: Probable 2-nitropropane dioxygenase; PFAM: 2-nitropropane dioxygenase YP_004099945.1 COGs: COG2385 sporulation protein and related protein; InterPro IPR013486: IPR013693: IPR007253; KEGG: bcv:Bcav_1179 SpoIID/LytB domain protein; PFAM: stage II sporulation protein D; cell wall binding repeat 2-containing protein; SPTR: LytC; TIGRFAM: SpoIID/LytB domain protein; manually curated; PFAM: cell wall binding repeat 2; stage II sporulation protein; TIGRFAM: SpoIID/LytB domain YP_004099946.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439: IPR003593; KEGG: bcv:Bcav_1325 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004099947.1 KEGG: scb:SCAB_68591 hypothetical protein; SPTR: uncharacterized protein YP_004099948.1 KEGG: jde:Jden_0674 glycogen/starch/alpha-glucan phosphorylase; SPTR: uncharacterized protein YP_004099949.1 COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406: IPR020097; KEGG: bcv:Bcav_3109 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; PRIAM: tRNA-pseudouridine synthase I; SPTR: tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_004099950.1 InterPro IPR001460; KEGG: sma:SAV_1039 hypothetical protein; PFAM: penicillin-binding protein transpeptidase; SPTR: uncharacterized protein YP_004099951.1 COGs: COG0203 ribosomal protein L17; InterPro IPR000456; KEGG: kse:Ksed_20580 50S ribosomal protein L17P; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_004099952.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterProIPR011263: IPR011260: IPR011773: IPR011261: IPR 011262; KEGG: scb:SCAB_36671 DNA-directed RNA polymerase subunit alpha; PFAM: RNA polymerase insert; RNA polymerase dimerisation; RNA polymerase alpha subunit domain protein; SMART: RNA polymerase RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, subunit alpha; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type YP_004099953.1 COGs: COG0522 ribosomal protein S4 and related protein; InterPro IPR002942: IPR005709: IPR001912: IPR018079; KEGG: nml:Namu_1171 30S ribosomal protein S4; PFAM: ribosomal protein S4; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4; PFAM: ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type YP_004099954.1 COGs: COG0100 ribosomal protein S11; InterPro IPR001971: IPR019981: IPR018102; KEGG: kra:Krad_0714 30S ribosomal protein S11; PFAM: ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; PFAM: ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11 YP_004099955.1 COGs: COG0099 ribosomal protein S13; InterPro IPR001892: IPR019980: IPR018269; KEGG: ske:Sked_29480 30S ribosomal protein S13P; PFAM: ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: 30S ribosomal protein S13; PFAM: ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13 YP_004099956.1 InterPro IPR000473; KEGG: kse:Ksed_20630 50S ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_004099957.1 COGs: COG0361 translation initiation factor 1 (IF-1); InterPro IPR006196: IPR004368; KEGG: jde:Jden_0609 translation initiation factor IF-1; PFAM: S1 IF1 family protein; SPTR: translation initiation factor; TIGRFAM: translation initiation factor IF-1; PFAM: translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_004099958.1 COGs: COG5646 conserved hypothetical protein; InterPro IPR014922; KEGG: ach:Achl_1025 hypothetical protein; PFAM: Domain of unknown function DUF1801; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DU1801) YP_004099959.1 KEGG: sma:SAV_48 hypothetical protein; SPTR: uncharacterized protein YP_004099960.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR004638: IPR001411: IPR011701; KEGG: nca:Noca_4349 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Albicidin efflux pump; TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter EmrB/QacA subfamily YP_004099961.1 COGs: COG0334 glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362: IPR006095: IPR006097: IPR006096; KEGG: nfa:nfa45920 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: glutamate dehydrogenase (NADP(+)); SPTR: glutamate dehydrogenase; PFAM: glutamate/Leucine/phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004099962.1 COGs: COG0024 methionine aminopeptidase; InterPro IPR002467: IPR001714: IPR000994; KEGG: kse:Ksed_20650 methionine aminopeptidase, type I; PFAM: peptidase M24; PRIAM: Methionyl aminopeptidase; SPTR: methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_004099963.1 COGs: COG0563 adenylate kinase and related kinase; InterPro IPR000850: IPR006259; KEGG: kse:Ksed_20660 adenylate kinase; PFAM: adenylate kinase; SPTR: adenylate kinase; TIGRFAM: adenylate kinase; PFAM: adenylate kinase; TIGRFAM: adenylate kinases YP_004099964.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208; KEGG: kra:Krad_0708 preprotein translocase, SecY subunit; PFAM: SecY protein; SPTR: Preprotein translocase SecY; TIGRFAM: preprotein translocase, SecY subunit; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit YP_004099965.1 COGs: COG0200 ribosomal protein L15; InterPro IPR005749: IPR001196; KEGG: cfl:Cfla_2640 ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: ribosomal protein L15; PFAM: ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_004099966.1 COGs: COG1841 ribosomal protein L30/L7E; InterPro IPR005996: IPR000517; KEGG: sro:Sros_1104 ribosomal protein L30p/L7e; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_004099967.1 COGs: COG0098 ribosomal protein S5; InterPro IPR013810: IPR005712: IPR005324: IPR018192; KEGG: kra:Krad_0705 ribosomal protein S5; PFAM: ribosomal protein S5; ribosomal protein S5 domain protein; SPTR: 30S ribosomal protein S5; TIGRFAM: ribosomal protein S5; PFAM: ribosomal protein S5, C-terminal domain; ribosomal protein S5, N-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_004099968.1 COGs: COG0256 ribosomal protein L18; InterPro IPR004389: IPR005484; KEGG: ach:Achl_2672 ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; SPTR: 50S ribosomal protein L18; TIGRFAM: ribosomal protein L18; PFAM: ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_004099969.1 COGs: COG0097 ribosomal protein L6P/L9E; InterPro IPR000702: IPR019906: IPR020040: IPR002358; KEGG: kse:Ksed_20720 50S ribosomal protein L6P; PFAM: ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: ribosomal protein L6; PFAM: ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type YP_004099970.1 COGs: COG0096 ribosomal protein S8; InterPro IPR000630; KEGG: rsa:RSal33209_2150 30S ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: 30S ribosomal protein S8; PFAM: ribosomal protein S8 YP_004099971.1 COGs: COG0199 ribosomal protein S14; InterPro IPR001209: IPR018271; KEGG: cfl:Cfla_2646 ribosomal protein S14; PFAM: ribosomal protein S14; SPTR: 30S ribosomal protein S14; PFAM: ribosomal protein S14p/S29e YP_004099972.1 COGs: COG0094 ribosomal protein L5; InterPro IPR002132: IPR020929; KEGG: kra:Krad_0700 ribosomal protein L5; SPTR: 50S ribosomal protein L5; PFAM: ribosomal L5P family C-terminus; ribosomal protein L5 YP_004099973.1 COGs: COG0198 ribosomal protein L24; InterPro IPR003256: IPR005824; KEGG: kse:Ksed_20760 50S ribosomal protein L24P; PFAM: KOW domain protein; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; TIGRFAM: ribosomal protein L24, bacterial/organelle YP_004099974.1 COGs: COG0093 ribosomal protein L14; InterPro IPR005745: IPR000218: IPR019972; KEGG: sma:SAV_4936 50S ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: ribosomal protein L14; PFAM: ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_004099975.1 COGs: COG0186 ribosomal protein S17; InterPro IPR000266: IPR019984: IPR019979; KEGG: nca:Noca_3896 30S ribosomal protein S17P; PFAM: ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17; PFAM: ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17 YP_004099976.1 InterPro IPR001854: IPR018254; KEGG: rsa:RSal33209_2157 50S ribosomal protein L29P; PFAM: ribosomal protein L29; SPTR: 50S ribosomal protein L29P; TIGRFAM: ribosomal protein L29; PFAM: ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_004099977.1 COGs: COG0197 ribosomal protein L16/L10E; InterPro IPR000114: IPR016180: IPR020798; KEGG: kse:Ksed_20800 50S ribosomal protein L16P; PFAM: ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: ribosomal protein L16; PFAM: ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_004099978.1 COGs: COG0092 ribosomal protein S3; InterProIPR004044: IPR004087: IPR005704: IPR008282: IPR 001351: IPR018280; KEGG: ach:Achl_2681 ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; ribosomal protein S3 domain; KH type 2 domain protein; SMART: KH domain protein; SPTR: 30S ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: KH domain; ribosomal protein S3, C-terminal domain; ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type YP_004099979.1 COGs: COG0091 ribosomal protein L22; InterPro IPR005727: IPR001063: IPR018054: IPR018260; KEGG: ske:Sked_29690 50S ribosomal protein L22P; PFAM: ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: ribosomal protein L22; PFAM: ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_004099980.1 COGs: COG0185 ribosomal protein S19; InterPro IPR002222: IPR005732: IPR020934; KEGG: jde:Jden_0591 30S ribosomal protein S19; PFAM: ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: ribosomal protein S19; PFAM: ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_004099981.1 COGs: COG0090 ribosomal protein L2; InterPro IPR002171: IPR005880; KEGG: kra:Krad_0691 50S ribosomal protein L2; PFAM: ribosomal protein L2; SPTR: 50S ribosomal protein L2; TIGRFAM: ribosomal protein L2; PFAM: ribosomal proteins L2, RNA binding domain; ribosomal proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar YP_004099982.1 COGs: COG0089 ribosomal protein L23; InterPro IPR013025; KEGG: kse:Ksed_20850 50S ribosomal protein L23P; PFAM: ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23P; PFAM: ribosomal protein L23 YP_004099983.1 COGs: COG0088 ribosomal protein L4; InterPro IPR002136; KEGG: kse:Ksed_20860 50S ribosomal protein L4P; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: ribosomal protein L4/L1 family YP_004099984.1 COGs: COG0087 ribosomal protein L3; InterPro IPR019927: IPR000597: IPR019926; KEGG: kse:Ksed_20870 50S ribosomal protein L3P; PFAM: ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3; PFAM: ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial YP_004099985.1 COGs: COG0051 ribosomal protein S10; InterPro IPR018268: IPR001848: IPR005731; KEGG: xce:Xcel_0626 ribosomal protein S10; PFAM: ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: ribosomal protein S10; PFAM: ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle YP_004099986.1 COGs: COG1362 aspartyl aminopeptidase; InterPro IPR001948; KEGG: nml:Namu_4174 aminopeptidase 2; PFAM: peptidase M18 aminopeptidase I; PRIAM: aspartyl aminopeptidase; SPTR: M18 family aminopeptidase; PFAM: Aminopeptidase I zinc metalloprotease (M18) YP_004099987.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR004541: IPR005225: IPR000795: IPR004161: IPR 004160; KEGG: sma:SAV_4920 elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain-containing protein; PRIAM: sulfate adenylyltransferase; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu C-terminal domain; Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004099988.1 COGs: COG0480 translation elongation factors (GTPase); InterProIPR004540: IPR005225: IPR000795: IPR004161: IPR 005517: IPR000640; KEGG: rsa:RSal33209_2172 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Elongation factor G; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004099989.1 COGs: COG0049 ribosomal protein S7; InterPro IPR005717: IPR000235: IPR020606; KEGG: kra:Krad_0683 30S ribosomal protein S7; PFAM: ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: ribosomal protein S7; PFAM: ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle YP_004099990.1 COGs: COG0048 ribosomal protein S12; InterPro IPR005679: IPR006032; KEGG: nca:Noca_3925 30S ribosomal protein S12; PFAM: ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: ribosomal protein S12; PFAM: ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle YP_004099991.1 KEGG: bcv:Bcav_1967 hypothetical protein; SPTR: uncharacterized protein YP_004099992.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; InterProIPR006592: IPR012754: IPR007080: IPR000722: IPR 007066: IPR007083: IPR007081; KEGG: kse:Ksed_20940 DNA-directed RNA polymerase subunit beta'; PFAM: RNA polymerase Rpb1 domain 1; RNA polymerase subunit alpha; RNA polymerase Rpb1 domain 3; RNA polymerase Rpb1 domain 4; RNA polymerase Rpb1 domain 5; SMART: RNA polymerase I subunit A domain protein; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 3; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form YP_004099994.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterProIPR010243: IPR007644: IPR007642: IPR007645: IPR 019462: IPR007120: IPR007641: IPR007121; KEGG: kra:Krad_0680 DNA-directed RNA polymerase subunit beta; PFAM: RNA polymerase Rpb2 domain 6; RNA polymerase Rpb2 domain 3; RNA polymerase subunit beta; RNA polymerase Rpb2 domain 2; DNA-directed RNA polymerase subunit beta, external 1 domain; RNA polymerase Rpb2 domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase subunit beta; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase subunit beta external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase subunit beta; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase subunit beta YP_004099995.1 COGs: COG2957 peptidylarginine deiminase; InterPro IPR007466; KEGG: aau:AAur_0974 peptidylarginine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; PRIAM: Agmatine deiminase; SPTR: peptidylarginine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase YP_004099996.1 COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: mab:MAB_2545c nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Hypothetical nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; manually curated; PFAM: carbon-nitrogen hydrolase YP_004099997.1 KEGG: kfl:Kfla_6144 hypothetical protein; SPTR: uncharacterized protein YP_004099998.1 KEGG: sma:SAV_5893 hypothetical protein; SPTR: uncharacterized protein YP_004099999.1 COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR003399: IPR005693; KEGG: sma:SAV_5894 mce-related protein; PFAM: Mammalian cell entry related domain protein; SPTR: mce-related protein; TIGRFAM: virulence factor Mce family protein; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_004100000.1 COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR003399: IPR005693; KEGG: sma:SAV_5895 mce-related protein; PFAM: Mammalian cell entry related domain protein; SPTR: mce-related protein; TIGRFAM: virulence factor Mce family protein; PFAM: protein of unknown function (DUF3407); mce related protein; TIGRFAM: virulence factor Mce family protein YP_004100001.1 COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR003399: IPR005693; KEGG: sma:SAV_5896 mce-related protein; PFAM: Mammalian cell entry related domain protein; SPTR: mce-related protein; TIGRFAM: virulence factor Mce family protein; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_004100002.1 COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR008360: IPR003399: IPR005693; KEGG: sma:SAV_5897 mce-related protein; PFAM: Mammalian cell entry related domain protein; SPTR: mce-related protein; TIGRFAM: virulence factor Mce family protein; PFAM: protein of unknown function (DUF3407); mce related protein; TIGRFAM: virulence factor Mce family protein YP_004100003.1 COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR003399: IPR005693; KEGG: sma:SAV_5898 mce-related protein; PFAM: Mammalian cell entry related domain protein; SPTR: mce-related protein; TIGRFAM: virulence factor Mce family protein; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_004100004.1 COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR003399: IPR005693; KEGG: sma:SAV_5899 mce-related protein; PFAM: Mammalian cell entry related domain protein; SPTR: mce-related protein; TIGRFAM: virulence factor Mce family protein; PFAM: protein of unknown function (DUF3407); mce related protein; TIGRFAM: virulence factor Mce family protein YP_004100005.1 COGs: COG0767 ABC-type transporter involved in resistance to organic solvents permease; InterPro IPR003453; KEGG: kfl:Kfla_6152 protein of unknown function DUF140; PFAM: protein of unknown function DUF140; SPTR: ABC transporter integral membrane protein; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004100006.1 COGs: COG0767 ABC-type transporter involved in resistance to organic solvents permease; InterPro IPR003453; KEGG: sma:SAV_5901 ABC transporter integral membrane protein; PFAM: protein of unknown function DUF140; SPTR: ABC transporter integral membrane protein; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004100007.1 COGs: COG1127 ABC-type transporter involved in resistance to organic solvents ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: nca:Noca_0700 ABC transporter; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004100008.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR017685; KEGG: xce:Xcel_2242 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; SPTR: transcriptional regulator, LysR family; TIGRFAM: transcriptional regulator, ArgP family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; TIGRFAM: transcriptional regulator, ArgP family YP_004100009.1 COGs: COG1279 lysine efflux permease; InterPro IPR001123; KEGG: rha:RHA1_ro03597 lysine exporter protein; PFAM: lysine exporter protein (LYSE/YGGA); SPTR: lysine exporter; PFAM: LysE type translocator; TIGRFAM: L-lysine exporter YP_004100010.1 KEGG: srt:Srot_1031 hypothetical protein; SPTR: uncharacterized protein YP_004100011.1 COGs: COG0222 ribosomal protein L7/L12; InterPro IPR013823: IPR000206: IPR010916; KEGG: gob:Gobs_4520 ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12; SPTR: ribosomal protein L7/L12; TIGRFAM: ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_004100012.1 COGs: COG0244 ribosomal protein L10; InterPro IPR001790; KEGG: fal:FRAAL1068 50S ribosomal protein L10; PFAM: ribosomal protein L10; SPTR: 50S ribosomal protein L10; PFAM: ribosomal protein L10 YP_004100013.1 KEGG: gob:Gobs_4249 hypothetical protein; SPTR: lipoprotein; PFAM: protein of unknown function (DUF3152) YP_004100014.1 COGs: COG0081 ribosomal protein L1; InterPro IPR002143: IPR005878; KEGG: nca:Noca_0697 50S ribosomal protein L1P; PFAM: ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: ribosomal protein L1; PFAM: ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast YP_004100015.1 COGs: COG0080 ribosomal protein L11; InterPro IPR000911: IPR020784: IPR020783: IPR006519; KEGG: sco:SCO4648 50S ribosomal protein L11; PFAM: ribosomal protein L11-like; SMART: ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: ribosomal protein L11, RNA binding domain; ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_004100016.1 COGs: COG0250 transcription antiterminator; InterProIPR006645: IPR001062: IPR005824: IPR018208: IPR 015869; KEGG: ske:Sked_29880 transcription antitermination protein NusG; PFAM: NGN domain-containing protein; KOW domain protein; SMART: NGN domain-containing protein; SPTR: transcription antitermination protein nusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription termination factor nusG; TIGRFAM: transcription termination/antitermination factor NusG YP_004100017.1 InterPro IPR001901: IPR005807; KEGG: kse:Ksed_21040 preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; SPTR: Preprotein translocase SecE subunit; TIGRFAM: preprotein translocase, SecE subunit; PFAM: SecE/Sec61-subunit gammas of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_004100018.1 COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: nca:Noca_0675 aminotransferase, class I and II; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II YP_004100019.1 KEGG: rop:ROP_18570 hypothetical protein; SPTR: uncharacterized protein YP_004100020.1 COGs: COG1816 adenosine deaminase; InterPro IPR006330: IPR001365: IPR006650; KEGG: kse:Ksed_21160 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: adenosine deaminase; SPTR: adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; TIGRFAM: adenosine deaminase YP_004100021.1 KEGG: ypy:YPK_4162 integrase; SPTR: integrase YP_004100022.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR016166: IPR003170: IPR006094: IPR011601; KEGG: kse:Ksed_21170 UDP-N-acetylmuramate dehydrogenase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain-containing protein; FAD linked oxidase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004100023.1 COGs: COG2030 acyl dehydratase; InterPro IPR002539; KEGG: sco:SCO4637 hypothetical protein; PFAM: MaoC domain protein dehydratase; SPTR: uncharacterized protein; PFAM: MaoC like domain YP_004100024.1 InterPro IPR016709; KEGG: aau:AAur_3002 hypothetical protein; SPTR: uncharacterized protein; PFAM: MaoC like domain YP_004100025.1 COGs: COG0267 ribosomal protein L33; InterPro IPR001705: IPR018264; KEGG: fal:FRAAL1059 50S ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004100026.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: xce:Xcel_0209 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF20 YP_004100027.1 KEGG: gob:Gobs_3869 hypothetical protein; SPTR: uncharacterized protein YP_004100028.1 InterPro IPR000182; KEGG: cmi:CMM_0281 acetyltransferase; SPTR: acetyltransferase YP_004100029.1 KEGG: kfl:Kfla_1341 hypothetical protein; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily YP_004100030.1 COGs: COG2409 drug exporter of the RND superfamily; InterPro IPR000731; KEGG: nfa:nfa25730 hypothetical protein; SPTR: membrane protein; PFAM: MMPL family YP_004100031.1 InterPro IPR007253; KEGG: ace:Acel_1679 protease-like; PFAM: cell wall binding repeat 2-containing protein; SPTR: Protease-like; PFAM: cell wall binding repeat 2 YP_004100032.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: tfu:Tfu_2810 hypothetical protein; PFAM: periplasmic binding protein; SPTR: uncharacterized protein; manually curated YP_004100033.1 COGs: COG1884 methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006158: IPR005129: IPR006099: IPR006098; KEGG: scb:SCAB_6731 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; ArgK protein; PRIAM: methylmalonyl-CoA mutase; SPTR: methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: ArgK protein; methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain YP_004100034.1 COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: rop:ROP_12400 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: transcriptional regulator; PFAM: MarR family YP_004100035.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000595: IPR003594: IPR005467: IPR004358; KEGG: rha:RHA1_ro04003 sensor kinase, two-component system; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SPTR: histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004100036.1 COGs: COG0492 thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain YP_004100037.1 COGs: COG0153 Galactokinase; InterProIPR006206: IPR000705: IPR019539: IPR006204: IPR 013750: IPR019741: IPR006203; KEGG: cfl:Cfla_2490 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase YP_004100038.1 COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR001937: IPR005849: IPR005850: IPR019779; KEGG: kra:Krad_3972 galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: Galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1 YP_004100039.1 InterPro IPR013216: IPR018486; KEGG: mgi:Mflv_3460 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004100040.1 KEGG: kra:Krad_1973 hypothetical protein; SPTR: uncharacterized protein YP_004100041.1 COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027; KEGG: mab:MAB_4368c rubredoxin/ferredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: CinA4; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004100042.1 KEGG: nml:Namu_4248 histidine kinase; SPTR: Signal sequence receptor subunit alpha YP_004100043.1 KEGG: kfl:Kfla_2258 hypothetical protein; SPTR: uncharacterized protein YP_004100044.1 COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: kfl:Kfla_2257 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: transcriptional regulator, MarR family; PFAM: MarR family YP_004100045.1 KEGG: nml:Namu_3920 hypothetical protein; SPTR: uncharacterized protein YP_004100046.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR002744: IPR019591: IPR000808; KEGG: rha:RHA1_ro11224 ATPase; PFAM: ATPase-like, ParA/MinD; protein of unknown function DUF59; SPTR: Possible ATPase; PFAM: ParA/MinD ATPase like; Domain of unknown function DUF59; Anion-transporting ATPase YP_004100047.1 COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963: IPR006656: IPR006657; KEGG: nca:Noca_2934 formate dehydrogenase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; PRIAM: nitrate reductase; SPTR: formate dehydrogenase; manually curated; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain YP_004100048.1 COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896: IPR005614: IPR017900; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: polysulphide reductase NrfD; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; polysulphide reductase, NrfD YP_004100049.1 InterPro IPR001455; KEGG: nca:Noca_2932 SirA family protein; PFAM: SirA-like domain-containing protein; SPTR: uncharacterized protein; PFAM: SirA-like protein YP_004100050.1 COGs: COG2210 conserved hypothetical protein; KEGG: rha:RHA1_ro11228 NADH dehydrogenase; SPTR: Possible NADH dehydrogenase YP_004100051.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: rha:RHA1_ro11229 hydroxyacylglutathione hydrolase; SMART: rhodanese; SPTR: Possible hydroxyacylglutathione hydrolase; PFAM: metallo-beta-lactamase superfamily; Rhodanese-like domain YP_004100052.1 InterPro IPR001845; KEGG: rha:RHA1_ro11232 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Probable ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004100053.1 COGs: COG1957 inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: nca:Noca_0542 inosine/uridine-preferring nucleoside hydrolase; PFAM: inosine/uridine-preferring nucleoside hydrolase; SPTR: inosine/uridine-preferring nucleoside hydrolase; PFAM: inosine-uridine preferring nucleoside hydrolase YP_004100054.1 InterPro IPR001647; KEGG: nda:Ndas_1121 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family YP_004100055.1 COGs: COG2409 drug exporter of the RND superfamily; InterPro IPR000731; KEGG: ske:Sked_37220 predicted RND superfamily drug exporter; SPTR: Predicted RND superfamily drug exporter; PFAM: MMPL family YP_004100056.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120: IPR020556; KEGG: rop:ROP_37880 amidase; PFAM: amidase; SPTR: amidase; PFAM: amidase YP_004100057.1 COGs: COG3568 metal-dependent hydrolase; InterPro IPR005135; KEGG: gob:Gobs_0808 endonuclease/exonuclease/phosphatase; PFAM: endonuclease/exonuclease/phosphatase; SPTR: endonuclease/exonuclease/phosphatase; PFAM: endonuclease/exonuclease/phosphatase family YP_004100058.1 KEGG: gob:Gobs_0809 hypothetical protein; SPTR: uncharacterized protein YP_004100059.1 COGs: COG3191 L-aminopeptidase/D-esterase; InterPro IPR005321: IPR002202; KEGG: sro:Sros_2464 aminopeptidase; PFAM: peptidase S58 DmpA; SPTR: Aminopeptidase; PFAM: peptidase family S58 YP_004100060.1 COGs: COG2205 osmosensitive K+ channel histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: cfl:Cfla_3552 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004100061.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: sco:SCO5872 turgor pressure regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Turgor pressure regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004100062.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638: IPR017200: IPR007197; KEGG: nca:Noca_1430 radical SAM domain-containing protein; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: radical SAM superfamily YP_004100063.1 KEGG: bcv:Bcav_1591 glycoside hydrolase family 2 sugar binding; SPTR: glycoside hydrolase family 2 sugar binding; PFAM: protein of unknown function (DUF2804) YP_004100064.1 InterPro IPR013096; KEGG: pfr:PFREUD_02140 hypothetical protein; PFAM: cupin; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004100065.1 COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524: IPR004839; KEGG: art:Arth_2457 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II YP_004100066.1 InterPro IPR000620; KEGG: aau:AAur_0278 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: integral membrane protein DUF6; manually curated; PFAM: EamA-like transporter family YP_004100067.1 KEGG: nml:Namu_5329 hypothetical protein; SPTR: uncharacterized protein YP_004100068.1 InterPro IPR012933; KEGG: sjp:SJA_C1-10090 YcfA-like protein; PFAM: YcfA family protein; SPTR: uncharacterized protein; PFAM: YcfA-like protein YP_004100069.1 KEGG: pak:HMPREF0675_3721 hypothetical protein; SPTR: uncharacterized protein YP_004100070.1 KEGG: rca:Rcas_1179 radical SAM domain-containing protein; SPTR: radical SAM protein YP_004100071.1 KEGG: rha:RHA1_ro11254 hypothetical protein; SPTR: uncharacterized protein YP_004100072.1 KEGG: fra:Francci3_0808 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1814) YP_004100073.1 InterPro IPR001387; KEGG: fra:Francci3_0807 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004100074.1 InterPro IPR004155; KEGG: xac:XAC1869 hypothetical protein; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: PBS lyase HEAT domain protein repeat-containing protein YP_004100075.1 InterPro IPR003587: IPR006141: IPR006530; KEGG: stp:Strop_1054 hypothetical protein; SMART: Hedgehog/intein hint domain protein; SPTR: hypothetical protein; TIGRFAM: hypothetical protein; PFAM: protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain YP_004100076.1 COGs: COG0580 glycerol uptake facilitator and related permease (Major Intrinsic protein Family); InterPro IPR000425: IPR012269; KEGG: mtp:Mthe_1139 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel proteins; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_004100077.1 COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR014184: IPR002328; KEGG: gob:Gobs_4986 formaldehyde dehydrogenase, glutathione-independent; PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; SPTR: Formaldehyde dehydrogenase, glutathione-independent; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent YP_004100078.1 InterPro IPR010093; KEGG: mbt:JTY_0764 transcriptional regulatory protein; SPTR: POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN; TIGRFAM: DNA binding domain protein, excisionase family; manually curated; TIGRFAM: DNA binding domain, excisionase family YP_004100079.1 COGs: COG1666 conserved hypothetical protein; InterPro IPR007551; KEGG: sma:SAV_4896 nucleotide-binding protein; PFAM: protein of unknown function DUF520; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF520) YP_004100080.1 COGs: COG0281 Malic enzyme; InterPro IPR001891: IPR002912: IPR012301: IPR012302; KEGG: nca:Noca_2034 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; SPTR: malate dehydrogenase (Oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_004100081.1 InterPro IPR000086; KEGG: kse:Ksed_21710 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004100082.1 KEGG: cms:CMS_2757 hypothetical protein; SPTR: uncharacterized protein; PFAM: proteins of 100 residues with WXG YP_004100083.1 COGs: COG0459 chaperonin GroEL (HSP60 family); InterPro IPR001844: IPR002423: IPR018370; KEGG: kra:Krad_3636 chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: chaperonin GroEL; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004100084.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310: IPR019808; KEGG: nca:Noca_1284 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: histidine triad (HIT) protein; PFAM: HIT domain YP_004100085.1 KEGG: kfl:Kfla_4775 membrane-bound lytic murein transglycosylase B-like protein; SPTR: membrane-bound lytic murein transglycosylase B-like protein YP_004100086.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: kfl:Kfla_2411 beta-lactamase; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily YP_004100087.1 COGs: COG3191 L-aminopeptidase/D-esterase; InterPro IPR005321; KEGG: sco:SCO3193 hypothetical protein; PFAM: peptidase S58 DmpA; SPTR: uncharacterized protein; PFAM: peptidase family S58 YP_004100088.1 InterPro IPR000182; KEGG: cwo:Cwoe_4235 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family YP_004100089.1 KEGG: cfl:Cfla_0686 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3263) YP_004100090.1 COGs: COG0076 glutamate decarboxylase and related PLP-dependent protein; InterPro IPR010977: IPR002129: IPR021115; KEGG: fra:Francci3_0279 pyridoxal-dependent decarboxylase; PFAM: pyridoxal-dependent decarboxylase; SPTR: pyridoxal-dependent decarboxylase; PFAM: pyridoxal-dependent decarboxylase conserved domain YP_004100091.1 COGs: COG0546 phosphatase; InterPro IPR005834: IPR006402: IPR006439; KEGG: sth:STH3141 phosphoglycolate phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; HAD-superfamily hydrolase, subfamily IIIA YP_004100092.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680: IPR003764; KEGG: tfu:Tfu_2473 N-acetylglucosamine 6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_004100093.1 COGs: COG0692 uracil DNA glycosylase; InterPro IPR002043: IPR005122: IPR018085; KEGG: svi:Svir_09210 uracil-DNA glycosylase; PFAM: uracil-DNA glycosylase; SPTR: uracil-DNA glycosylase; PFAM: uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase YP_004100094.1 InterPro IPR001087; KEGG: kse:Ksed_21860 GDSL-like lipase/acylhydrolase; PFAM: lipolytic protein G-D-S-L family; SPTR: uncharacterized protein; PFAM: GDSL-like Lipase/acylhydrolase YP_004100095.1 KEGG: nca:Noca_4159 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF559) YP_004100096.1 COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814: IPR004632; KEGG: nml:Namu_4960 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; SPTR: 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type YP_004100097.1 COGs: COG3832 conserved hypothetical protein; InterPro IPR013538; KEGG: nml:Namu_5220 activator of HSP90 ATPase 1 family protein; PFAM: activator of Hsp90 ATPase 1 family protein; SPTR: activator of Hsp90 ATPase 1 family protein; PFAM: activator of Hsp90 ATPase homolog 1-like protein YP_004100098.1 InterPro IPR001845; KEGG: nml:Namu_5219 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004100099.1 InterPro IPR000551: IPR005116: IPR004606; KEGG: ami:Amir_1951 DNA binding domain protein, excisionase family; PFAM: TOBE domain-containing protein; regulatory protein MerR; SPTR: DNA binding domain protein, excisionase family; PFAM: TOBE domain; TIGRFAM: molybdenum-pterin binding domain; DNA binding domain, excisionase family YP_004100100.1 COGs: COG0725 ABC-type molybdate transporter periplasmic component; InterPro IPR006059: IPR005950: IPR010916; KEGG: kfl:Kfla_6495 molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Molybdenum ABC transporter periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein YP_004100101.1 COGs: COG0555 ABC-type sulfate transporter permease component; InterPro IPR000515: IPR006469: IPR011867; KEGG: nfa:nfa43290 transporter; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: transporter; TIGRFAM: molybdate ABC transporter inner membrane subunit; NifC-like ABC-type porter; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: molybdate ABC transporter permease; NifC-like ABC-type porter YP_004100102.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593: IPR003439: IPR005116: IPR017871; KEGG: sma:SAV_1721 ABC transporter ATP-binding protein; PFAM: ABC transporter related; TOBE domain-containing protein; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; TOBE domain YP_004100103.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: kse:Ksed_21870 acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004100104.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904; KEGG: kfl:Kfla_1044 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004100105.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014325: IPR014284; KEGG: nca:Noca_3654 sigma-70, region 4 type 2; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: Sigma-70, region 4 type 2; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_004100106.1 InterPro IPR019775; KEGG: bxe:Bxe_A3682 hypothetical protein; SPTR: uncharacterized protein YP_004100107.1 InterPro IPR004843; KEGG: sus:acid_0081 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004100108.1 InterPro IPR011701; KEGG: ade:Adeh_0552 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1 transporter; PFAM: Major Facilitator Superfamily YP_004100109.1 COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR017439: IPR002933: IPR011650: IPR010168; KEGG: mcu:HMPREF0573_11409 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase YP_004100110.1 COGs: COG1522 transcriptional regulators; InterPro IPR019888: IPR019887; KEGG: rer:RER_25740 AsnC family transcriptional regulator; PFAM: transcription regulator AsnC-type-like; SMART: transcription regulator AsnC-type; SPTR: AsnC family transcriptional regulator; PFAM: AsnC family YP_004100111.1 KEGG: dwi:Dwil_GK12364 GK12364 gene product from transcript GK12364-RA; SPTR: uncharacterized protein YP_004100112.1 COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: amd:AMED_3739 N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) YP_004100113.1 InterPro IPR004360; KEGG: rha:RHA1_ro03837 hypothetical protein; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein YP_004100114.1 COGs: COG2409 drug exporter of the RND superfamily; KEGG: gob:Gobs_2362 MmpL domain protein; SPTR: MMPL domain protein; PFAM: MMPL family YP_004100115.1 InterPro IPR000540; KEGG: sgr:SGR_466 hypothetical protein; SPTR: uncharacterized protein YP_004100116.1 COGs: COG1278 Cold shock protein; InterPro IPR011129: IPR002059: IPR012156: IPR019844; KEGG: sma:SAV_826 cold shock protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: cold shock protein; PFAM: 'Cold-shock' DNA-binding domain YP_004100117.1 KEGG: pjd:Pjdr2_2870 hypothetical protein; SPTR: uncharacterized protein YP_004100118.1 InterPro IPR000326; KEGG: nca:Noca_1553 undecaprenyl-diphosphatase; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: undecaprenyl-diphosphatase; PFAM: PAP2 superfamily YP_004100119.1 COGs: COG4331 membrane protein; InterPro IPR021125; KEGG: mlo:mll8055 hypothetical protein; PFAM: protein of unknown function DUF2127; SPTR: Mll8055 protein; PFAM: Predicted membrane protein (DUF2127) YP_004100120.1 InterPro IPR003018: IPR003594: IPR018247; KEGG: cai:Caci_4163 PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004100121.1 KEGG: ani:AN2962.2 similar to GABA permease; SPTR: uncharacterized protein YP_004100122.1 COGs: COG3093 Plasmid maintenance system antidote protein; InterPro IPR001387: IPR013430; KEGG: sen:SACE_0851 plasmid maintenance system antidote protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Plasmid maintenance system antidote protein; TIGRFAM: addiction module antidote protein, HigA family; PFAM: Helix-turn-helix; TIGRFAM: addiction module antidote protein, HigA family YP_004100123.1 COGs: COG3549 Plasmid maintenance system killer protein; InterPro IPR007711; KEGG: jde:Jden_0767 plasmid maintenance system killer; PFAM: plasmid maintenance system killer; SPTR: Plasmid maintenance system killer; manually curated; PFAM: Plasmid maintenance system killer protein YP_004100124.1 KEGG: mmi:MMAR_3594 hypothetical protein; SPTR: uncharacterized protein YP_004100125.1 InterPro IPR014942; KEGG: mmi:MMAR_3595 hypothetical protein; PFAM: Domain of unknown function DUF1814; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1814) YP_004100126.1 KEGG: cfl:Cfla_2896 hypothetical protein; SPTR: cell surface protein YP_004100127.1 KEGG: cel:ZC477.1 Sperm-Specific family, class Q; SPTR: Sperm-specific family, class q protein 3 YP_004100128.1 InterPro IPR002482: IPR010618: IPR018392; KEGG: cai:Caci_5954 transglycosylase domain protein; PFAM: transglycosylase; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: uncharacterized protein; PFAM: transglycosylase-like domain; LysM domain YP_004100129.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR020635: IPR002290: IPR000719: IPR017442: IPR 017441: IPR008271; KEGG: kra:Krad_0921 protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Tyrosine protein kinase:serine/threonine protein kinase; PFAM: protein kinase domain YP_004100130.1 COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644; KEGG: nca:Noca_1696 CBS domain-containing protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: uncharacterized protein; PFAM: CBS domain YP_004100131.1 COGs: COG0380 Trehalose-6-phosphate synthase; InterPro IPR001830; KEGG: kse:Ksed_03840 trehalose 6-phosphate synthase; PFAM: glycosyl transferase family 20; PRIAM: alpha,alpha-trehalose-phosphate synthase (UDP-forming); SPTR: Trehalose 6-phosphate synthase; PFAM: glycosyltransferase family 20; TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming] YP_004100132.1 COGs: COG1877 Trehalose-6-phosphatase; InterPro IPR003337: IPR006379; KEGG: srt:Srot_2943 trehalose-phosphatase; PFAM: trehalose-phosphatase; SPTR: Trehalose-phosphatase; TIGRFAM: trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Trehalose-phosphatase; TIGRFAM: trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB YP_004100133.1 COGs: COG1609 transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: kfl:Kfla_1065 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family YP_004100134.1 COGs: COG0366 glycosidase; InterPro IPR006589: IPR006047; KEGG: sro:Sros_3328 maltodextrin glucosidase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Maltodextrin glucosidase; PFAM: alpha amylase, catalytic domain YP_004100135.1 COGs: COG3833 ABC-type maltose transporters permease component; InterPro IPR000515; KEGG: kse:Ksed_03810 carbohydrate ABC transporter membrane protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: carbohydrate ABC transporter membrane protein; PFAM: Binding-protein-dependent transporter inner membrane component YP_004100136.1 COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: kse:Ksed_03800 permease of ABC-type sugar transporter; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Permease component of ABC-type sugar transporter; PFAM: Binding-protein-dependent transporter inner membrane component YP_004100137.1 COGs: COG2182 maltose-binding periplasmic protein/domains; InterPro IPR006060: IPR006059; KEGG: kse:Ksed_03790 maltose-binding periplasmic protein; PFAM: extracellular solute-binding protein family 1; SPTR: maltose-binding periplasmic protein; PFAM: Bacterial extracellular solute-binding protein YP_004100138.1 COGs: COG3839 ABC-type sugar transporters ATPase components; InterPro IPR003593: IPR003439: IPR005116: IPR017871; KEGG: ach:Achl_0867 ABC transporter; PFAM: ABC transporter; TOBE domain-containing protein; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; TOBE domain YP_004100139.1 KEGG: bcv:Bcav_1237 hypothetical protein; SPTR: uncharacterized protein YP_004100140.1 KEGG: kra:Krad_0915 hypothetical protein; SPTR: uncharacterized protein; PFAM: Lipopolysaccharide kinase (Kdo/WaaP) family YP_004100141.1 COGs: COG4243 membrane protein; InterPro IPR012932; KEGG: afo:Afer_0226 vitamin K epoxide reductase; PFAM: Vitamin K epoxide reductase; SMART: Vitamin K epoxide reductase; SPTR: Vitamin K epoxide reductase; PFAM: Vitamin K epoxide reductase family YP_004100142.1 InterPro IPR009272; KEGG: ace:Acel_2067 hypothetical protein; PFAM: protein of unknown function DUF929; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF929) YP_004100143.1 COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: cfl:Cfla_0672 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: tRNA/rRNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, , group 3 YP_004100144.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803: IPR015273: IPR002308; KEGG: kse:Ksed_03760 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; manually curated; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase YP_004100145.1 COGs: COG4412 conserved hypothetical protein; InterPro IPR008757: IPR017683; KEGG: tbi:Tbis_2142 M6 family metalloprotease domain-containing protein; PFAM: peptidase M6 immune inhibitor A; SPTR: secreted protease; TIGRFAM: M6 family metalloprotease domain protein; PFAM: Immune inhibitor A peptidase M6; TIGRFAM: M6 family metalloprotease domain YP_004100146.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; InterPro IPR003526: IPR020555; KEGG: ach:Achl_0854 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase; PRIAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: YgbB family; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004100147.1 COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002347: IPR002198: IPR020904; KEGG: sro:Sros_0955 short-chain alcohol dehydrogenase of unknown specificity; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: oxidoreductase; PFAM: short chain dehydrogenase YP_004100148.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR001228: IPR018294; KEGG: kse:Ksed_03730 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004100149.1 COGs: COG1329 transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: kra:Krad_0898 CarD family transcriptional regulator; PFAM: transcription factor CarD; SPTR: CarD family transcriptional regulator; PFAM: CarD-like/TRCF domain YP_004100150.1 KEGG: cfl:Cfla_0662 lipoprotein; SPTR: lipoprotein YP_004100151.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: kra:Krad_0896 transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004100152.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: ach:Achl_0849 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: two-component system sensor kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004100153.1 COGs: COG0704 phosphate uptake regulator; InterPro IPR008170; KEGG: cai:Caci_8217 phosphate uptake regulator, PhoU; PFAM: PhoU family protein; SPTR: phosphate transporter regulator; TIGRFAM: phosphate transporter regulatory protein PhoU; PFAM: PhoU domain; TIGRFAM: phosphate transporter regulatory protein PhoU YP_004100154.1 COGs: COG0588 phosphoglycerate mutase 1; InterPro IPR005952: IPR013078: IPR001345; KEGG: nca:Noca_4043 phosphoglyceromutase; PFAM: phosphoglycerate mutase; PRIAM: phosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase 1 family; PFAM: phosphoglycerate mutase family; TIGRFAM: phosphoglycerate mutase, BPG-dependent, family 1 YP_004100155.1 InterPro IPR019706; KEGG: sgr:SGR_3994 hypothetical protein; PFAM: protein of unknown function DUF2596; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2596) YP_004100156.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296: IPR017814; KEGG: kra:Krad_0890 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase; TIGRFAM: UDP-N-acetylglucosamine; PFAM: glycosyl transferases group 1; TIGRFAM: UDP-N-acetylglucosamine: 1L-myo-inositol-1-phosphate 1-alpha-D-N-acetylglucosaminyltransferase YP_004100157.1 KEGG: aau:AAur_0891 hypothetical protein; SPTR: uncharacterized protein YP_004100158.1 COGs: COG0662 mannose-6-phosphate isomerase; InterPro IPR001538; KEGG: kse:Ksed_18490 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; SPTR: mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase YP_004100159.1 InterPro IPR019662; KEGG: kra:Krad_0886 integral membrane protein; PFAM: protein of unknown function DUF2516; SPTR: integral membrane protein; PFAM: protein of unknown function (DUF2516) YP_004100160.1 COGs: COG1490 D-Tyr-tRNAtyr deacylase; InterPro IPR003732; KEGG: xce:Xcel_3022 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase YP_004100161.1 COGs: COG4448 L-asparaginase II; InterPro IPR010349; KEGG: kse:Ksed_03610 L-asparaginase II; PFAM: L-asparaginase II; SPTR: uncharacterized protein; PFAM: L-asparaginase II YP_004100162.1 KEGG: tpr:Tpau_0881 hypothetical protein; SPTR: uncharacterized protein YP_004100163.1 InterPro IPR001387; KEGG: tcu:Tcur_0663 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix YP_004100164.1 KEGG: eat:EAT1b_1071 hypothetical protein; SPTR: uncharacterized protein YP_004100165.1 COGs: COG3246 conserved hypothetical protein; InterPro IPR008567; KEGG: kfl:Kfla_0987 protein of unknown function DUF849; PFAM: protein of unknown function DUF849; SPTR: uncharacterized protein; PFAM: Prokaryotic protein of unknown function (DUF849) YP_004100166.1 COGs: COG0354 aminomethyltransferase related to GcvT; InterPro IPR006222: IPR013977: IPR017703; KEGG: kse:Ksed_03590 folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; SPTR: uncharacterized protein; TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ YP_004100167.1 InterPro IPR014878; KEGG: kse:Ksed_03570 protein of unknown function (DUF1794); PFAM: Domain of unknown function DUF1794; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1794) YP_004100168.1 COGs: COG2044 peroxiredoxins; KEGG: tfu:Tfu_2924 hypothetical protein; SPTR: uncharacterized protein; PFAM: DsrE/DsrF-like family YP_004100169.1 KEGG: ske:Sked_04940 hypothetical protein; SPTR: uncharacterized protein YP_004100170.1 InterPro IPR003749; KEGG: mmi:MMAR_4664 molybdenum cofactor biosynthesis protein D 2 MoaD2; PFAM: thiamineS protein; SPTR: molybdopterin converting factor; PFAM: ThiS family YP_004100171.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: tcu:Tcur_0595 transcriptional regulator; PFAM: transcriptional regulator domain-containing protein; SPTR: transcriptional regulatory protein; PFAM: transcriptional regulatory protein, C terminal YP_004100172.1 InterPro IPR000182: IPR017813; KEGG: gob:Gobs_4647 mycothiol biosynthesis acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Mycothiol biosynthesis acetyltransferase; TIGRFAM: mycothiol biosynthesis acetyltransferase; PFAM: acetyltransferase (GNAT) family; TIGRFAM: mycothiol biosynthesis acetyltransferase YP_004100173.1 COGs: COG0855 polyphosphate kinase; InterPro IPR001736: IPR003414; KEGG: kra:Krad_0877 polyphosphate kinase; PFAM: polyphosphate kinase; PRIAM: polyphosphate kinase; SPTR: polyphosphate kinase; TIGRFAM: polyphosphate kinase; PFAM: polyphosphate kinase; TIGRFAM: polyphosphate kinase 1 YP_004100174.1 COGs: COG2062 phosphohistidine phosphatase SixA; InterPro IPR000086: IPR013078: IPR020084; KEGG: kse:Ksed_03520 ADP-ribose pyrophosphatase; PFAM: NUDIX hydrolase; phosphoglycerate mutase; SPTR: uncharacterized protein; PFAM: NUDIX domain; phosphoglycerate mutase family YP_004100175.1 COGs: COG0226 ABC-type phosphate transporter periplasmic component; InterPro IPR006059: IPR005673; KEGG: kra:Krad_0875 phosphate ABC transporter periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: phosphate-binding protein; TIGRFAM: phosphate ABC transporter periplasmic phosphate-binding protein; TIGRFAM: phosphate ABC transporter phosphate-binding protein YP_004100176.1 COGs: COG0573 ABC-type phosphate transporter permease; InterPro IPR000515: IPR011864; KEGG: kra:Krad_0874 phosphate ABC transporter inner membrane subunit PstC; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: phosphate transporter permease; TIGRFAM: phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: phosphate ABC transporter permease PstC YP_004100177.1 COGs: COG0581 ABC-type phosphate transporter permease; InterPro IPR000515: IPR005672; KEGG: kfl:Kfla_0961 phosphate ABC transporter inner membrane subunit PstA; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: phosphate transporter permease; TIGRFAM: phosphate ABC transporter inner membrane subunit PstA; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: phosphate ABC transporter permease PstA YP_004100178.1 COGs: COG1117 ABC-type phosphate transporter ATPase component; InterProIPR003593: IPR003439: IPR015850: IPR005670: IPR 017871; KEGG: kra:Krad_0872 phosphate transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: phosphate transport ATP-binding protein; TIGRFAM: phosphate ABC transporter ATPase; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter ATP-binding protein YP_004100179.1 COGs: COG0306 phosphate/sulfate permease; InterPro IPR001204; KEGG: sro:Sros_0892 phosphate transporter; PFAM: phosphate transporter; SPTR: low-affinity inorganic phosphate transporter; PFAM: phosphate transporter family YP_004100180.1 COGs: COG1392 phosphate transport regulator (distant homolog of PhoU); InterPro IPR018445; KEGG: sma:SAV_4077 Pit accessory protein; PFAM: Putitive phosphate transport regulator; SPTR: Pit accessory protein; PFAM: protein of unknown function DUF47; TIGRFAM: conserved hypothetical protein TIGR00153 YP_004100181.1 KEGG: nda:Ndas_5482 hypothetical protein; SPTR: uncharacterized protein YP_004100182.1 SPTR: uncharacterized protein; manually curated YP_004100183.1 KEGG: kse:Ksed_06930 hypothetical protein; SPTR: uncharacterized protein YP_004100184.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: gob:Gobs_3520 integrase; PFAM: integrase; SPTR: integrase; PFAM: Phage integrase family YP_004100185.1 KEGG: saq:Sare_3570 excisionase/Xis, DNA-binding; SPTR: Excisionase/Xis, DNA-binding; TIGRFAM: DNA binding domain, excisionase family YP_004100186.1 KEGG: sro:Sros_7035 hypothetical protein; SPTR: uncharacterized protein YP_004100187.1 KEGG: tcu:Tcur_4586 signal transduction protein with NACHT domain; SPTR: signal transduction protein with Nacht domain YP_004100188.1 KEGG: nve:NEMVE_v1g219223 hypothetical protein; SPTR: Predicted protein YP_004100189.1 KEGG: dvl:Dvul_0999 glycogen branching enzyme; SPTR: 1,4-alpha-glucan-branching enzyme YP_004100190.1 KEGG: ctc:CTC00495 internalin A-like protein/ S-layer protein; SPTR: Internalin A-like protein/ S-layer protein YP_004100191.1 KEGG: scb:SCAB_26861 lipoprotein; SPTR: uncharacterized protein YP_004100192.1 KEGG: rso:RS03124 transmembrane efflux transmembrane protein; SPTR: uncharacterized protein YP_004100193.1 InterPro IPR001584: IPR002514: IPR001523; KEGG: nml:Namu_1602 integrase catalytic region; PFAM: Integrase catalytic region; transposase IS3/IS911 family protein; paired box domain protein; SPTR: Integrase catalytic region; PFAM: Integrase core domain; transposase YP_004100194.1 KEGG: rno:502571 similar to TDPOZ3; SPTR: uncharacterized protein YP_004100195.1 KEGG: mlb:MLBr_00758 F420-0--gamma-glutamyl ligase; SPTR: oxidoreductase YP_004100196.1 KEGG: dre:562197 wu:fc75c05; SPTR: serine protease YP_004100197.1 KEGG: rce:RC1_0943 the GLUG motif domain protein, SPTR: The GLUG motif domain protein YP_004100198.1 COGs: COG4115 conserved hypothetical protein; InterPro IPR007712: IPR012753: IPR009614; KEGG: aeh:Mlg_1786 addiction module antitoxin; PFAM: plasmid stabilization system; SPTR: Possible addiction module toxin; TIGRFAM: addiction module toxin, Txe/YoeB family; addiction module toxin, RelE/StbE family; PFAM: Plasmid encoded toxin Txe; TIGRFAM: addiction module toxin, RelE/StbE family; toxin-antitoxin system, toxin component, Txe/YoeB family YP_004100199.1 InterPro IPR006442; KEGG: dal:Dalk_1773 prevent-host-death family protein; SPTR: Toxin-antitoxin system, antitoxin component, PHD family; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004100200.1 KEGG: kfl:Kfla_4609 cell divisionFtsK/SpoIIIE; SPTR: cell divisionFtsK/SpoIIIE YP_004100201.1 KEGG: pac:PPA0649 cytochrome oxidase assembly protein; SPTR: cytochrome oxidase assembly protein; PFAM: cytochrome oxidase assembly protein YP_004100202.1 KEGG: rha:RHA1_ro11214 hypothetical protein; SPTR: uncharacterized protein YP_004100203.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593: IPR003439; KEGG: nfa:pnf1870 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004100204.1 KEGG: nca:Noca_3778 hypothetical protein; SPTR: uncharacterized protein YP_004100205.1 COGs: COG1225 peroxiredoxin; InterPro IPR017936: IPR000866: IPR001917; KEGG: cfl:Cfla_0356 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family YP_004100206.1 COGs: COG0785 cytochrome C biogenesis protein; InterPro IPR003834; KEGG: cfl:Cfla_0355 cytochrome C biogenesis protein transmembrane region; PFAM: cytochrome C biogenesis protein transmembrane region; SPTR: cytochrome C biogenesis protein transmembrane region; PFAM: cytochrome C biogenesis protein transmembrane region YP_004100207.1 InterPro IPR008554; KEGG: nca:Noca_3783 glutaredoxin 2; PFAM: glutaredoxin 2; SPTR: glutaredoxin 2 YP_004100208.1 KEGG: cfl:Cfla_3678 hypothetical protein; SPTR: uncharacterized protein YP_004100210.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: mjl:Mjls_4548 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1937 YP_004100211.1 COGs: COG2217 Cation transport ATPase; InterProIPR011017: IPR001757: IPR000695: IPR008250: IPR 005834: IPR007029: IPR006403: IPR006416: IPR018303; KEGG: nca:Noca_2922 copper-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; YHS domain-containing protein; SMART: TRASH domain-containing protein; SPTR: Copper-translocating P-type ATPase; TIGRFAM: copper-translocating P-type ATPase; ATPase P; ATPase P; PFAM: YHS domain; E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; ATPase P; ATPase P YP_004100212.1 KEGG: art:Arth_3788 transmembrane anti-sigma factor; SPTR: transmembrane anti-sigma factor YP_004100213.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: cfl:Cfla_3677 prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004100214.1 KEGG: nca:Noca_2923 hypothetical protein; SPTR: uncharacterized protein YP_004100215.1 KEGG: oca:OCAR_5120 PAS/PAC sensor signal transduction histidine kinase; SPTR: uncharacterized protein YP_004100216.1 COGs: COG2132 multicopper oxidase; InterProIPR017909: IPR011707: IPR001117: IPR011706: IPR 002355; KEGG: pfr:PFREUD_19350 multicopper oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 1; multicopper oxidase type 2; SPTR: Multicopper oxidase; PFAM: Multicopper oxidase; TIGRFAM: copper-resistance protein, CopA family YP_004100217.1 InterPro IPR018649; KEGG: rop:ROP_pROB01-02360 hypothetical membrane protein; PFAM: protein of unknown function DUF2078, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2078) YP_004100218.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: rha:RHA1_ro11203 response regulator, two-component system; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator, two-component system; manually curated; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004100219.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: mlu:Mlut_18370 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004100220.1 COGs: COG3391 conserved hypothetical protein; InterPro IPR011964; KEGG: nca:Noca_3772 YVTN beta-propeller repeat-containing protein; SPTR: 40-residue YVTN family beta-propeller repeat protein; TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: 3-carboxy-cis,cis-muconate lactonizing enzyme; TIGRFAM: 40-residue YVTN family beta-propeller repeat YP_004100221.1 KEGG: dds:Ddes_0873 protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein YP_004100222.1 COGs: COG1290 cytochrome b subunit of the bc complex; InterPro IPR005797: IPR019794; KEGG: nca:Noca_2944 cytochrome b/b6 domain-containing protein; PFAM: cytochrome b/b6 domain; SPTR: cytochrome b/b6, N-terminal domain; PFAM: cytochrome b(N-terminal)/b6/petB YP_004100223.1 KEGG: bvu:BVU_4134 beta-galactosidase; SPTR: Heavy metal efflux pump, CzcA family YP_004100224.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: nca:Noca_2943 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004100225.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594: IPR005467: IPR013767: IPR011712; KEGG: nca:Noca_2942 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: ATP-binding region, ATPase domain protein domain protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004100226.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551: IPR015358; KEGG: fal:FRAAL6238 regulatory protein; PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; SPTR: MerR family transcriptional regulator; PFAM: MerR family regulatory protein; MerR, DNA binding YP_004100227.1 COGs: COG0659 sulfate permease and related transporter (MFS superfamily); InterPro IPR002645: IPR011547; KEGG: rop:ROP_00250 SulP family transporter; PFAM: sulfate transporter; sulfate transporter/antisigma-factor antagonist STAS; SPTR: SulP family transporter; PFAM: sulfate transporter family; STAS domain YP_004100228.1 COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR011108; KEGG: kra:Krad_1789 beta-lactamase domain protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_004100229.1 KEGG: bge:BC1002_2826 VacJ family lipoprotein; SPTR: VacJ family lipoprotein YP_004100230.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: sro:Sros_3423 response regulator receiver protein; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004100231.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: nca:Noca_1614 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: ATP-binding region, ATPase domain protein domain protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004100232.1 KEGG: ana:alr3644 aspartate kinase; SPTR: uncharacterized protein YP_004100233.1 COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268: IPR020396; KEGG: tcu:Tcur_4707 NADH dehydrogenase (ubiquinone) 30 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone) 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; nickel-dependent hydrogenase YP_004100234.1 COGs: COG0651 formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR003918: IPR001750; KEGG: tcu:Tcur_4706 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH/Ubiquinone/plastoquinone (Complex I); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains YP_004100235.1 COGs: COG4237 hydrogenase 4 membrane component (E); KEGG: tcu:Tcur_4705 hypothetical protein; SPTR: uncharacterized protein YP_004100236.1 COGs: COG0650 formate hydrogenlyase subunit 4; KEGG: nml:Namu_2986 respiratory-chain NADH dehydrogenase, subunit 1; SPTR: Respiratory-chain NADH dehydrogenase, subunit 1; PFAM: NADH dehydrogenase YP_004100237.1 COGs: COG0651 formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR003918: IPR001750; KEGG: tcu:Tcur_4703 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH/Ubiquinone/plastoquinone (Complex I); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains YP_004100238.1 COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: nml:Namu_2984 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit YP_004100239.1 InterPro IPR001845; KEGG: nml:Namu_2983 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004100240.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: kse:Ksed_04930 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: histidine kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004100241.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: nca:Noca_3782 response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004100242.1 KEGG: sen:SACE_2463 hypothetical protein; SPTR: uncharacterized protein YP_004100243.1 InterPro IPR018649; KEGG: rxy:Rxyl_3081 hypothetical protein; PFAM: protein of unknown function DUF2078, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2078) YP_004100244.1 COGs: COG2508 Regulator of polyketide synthase expression; KEGG: sen:SACE_1980 CdaR family transcriptional regulator; SPTR: CdaR family transcriptional regulator YP_004100245.1 KEGG: bxe:Bxe_A2270 phenylacetic acid degradation-related protein; SPTR: Phenylacetic acid degradation-related protein; TIGRFAM: uncharacterized domain 1 YP_004100246.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833: IPR005834: IPR006328: IPR006388; KEGG: bac:BamMC406_6135 haloacid dehalogenase, type II; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase, type II; TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; 2-haloalkanoic acid dehalogenase, type II YP_004100247.1 COGs: COG1011 hydrolase (HAD superfamily); KEGG: rrs:RoseRS_0250 HAD family hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1 YP_004100248.1 COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: kfl:Kfla_3588 formyl-CoA transferase; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; SPTR: Formyl-CoA transferase; PFAM: CoA-transferase family III YP_004100249.1 COGs: COG0777 acetyl-CoA carboxylase beta subunit; InterPro IPR011762: IPR011763: IPR000438: IPR000022; KEGG: nca:Noca_4502 carboxyl transferase; PFAM: carboxyl transferase; SPTR: carboxyl transferase; PFAM: carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase subunit beta YP_004100250.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tcu:Tcur_3752 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004100251.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: kcr:Kcr_0825 ABC-type branched-chain amino acid transporter, ATPase component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type branched-chain amino acid transporter ATPase component; PFAM: ABC transporter YP_004100252.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593: IPR003439; KEGG: hvo:HVO_A0579 ABC-type transporter ATP-binding protein (probable substrate branched-chain amino acids); PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type transporter ATP-binding protein (Probable substrate branched-chain amino acids); PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004100253.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: ade:Adeh_2426 ABC branched-chain amino acid transporter inner membrane subunit; PFAM: inner-membrane translocator; SPTR: Branched-chain amino acid ABC superfamily ATP binding cassette transporter permease; PFAM: Branched-chain amino acid transporter / permease YP_004100254.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: ank:AnaeK_1438 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004100255.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR001828; KEGG: bpa:BPP2097 branched-chain amino-acid ABC transporter substrate-binding protein; PFAM: extracellular ligand-binding receptor; SPTR: branched-chain amino acid transporter substrate-binding protein; PFAM: Receptor family ligand binding region YP_004100256.1 COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: tro:trd_1364 protein C7orf10; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; SPTR: protein C7orf10; PFAM: CoA-transferase family III YP_004100257.1 COGs: COG2186 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sen:SACE_3859 GntR family transcriptional regulator; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004100258.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: tpr:Tpau_0926 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase 2; PFAM: Amidohydrolase YP_004100259.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: tra:Trad_2055 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; manually curated; PFAM: glycosyl transferases group 1 YP_004100260.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296: IPR000408; KEGG: fal:FRAAL1700 phosphatidylinositol alpha-mannosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004100261.1 KEGG: fal:FRAAL1701 glycosyltransferase; SPTR: glycosyl transferase YP_004100262.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: mva:Mvan_1054 glycosidase, PH1107-related; PFAM: glycosidase related protein; SPTR: glycosidase, PH1107-related; PFAM: Domain of unknown function (DUF377) YP_004100263.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: pak:HMPREF0675_5336 aminotransferase, class IV; PFAM: aminotransferase class IV; SPTR: uncharacterized protein; PFAM: Aminotransferase class IV YP_004100264.1 COGs: COG1553 conserved hypothetical protein involved in intracellular sulfur reduction; InterPro IPR003787; KEGG: rfr:Rfer_0463 DsrE-like protein; PFAM: DsrE family protein; SPTR: DsrE-like protein; PFAM: DsrE/DsrF-like family YP_004100265.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: mtu:Rv0323c hypothetical protein; PFAM: LmbE family protein; SPTR: uncharacterized protein; PFAM: GlcNAc-PI de-N-acetylase YP_004100266.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: art:Arth_3087 alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase GroES; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004100267.1 InterPro IPR018506: IPR019758; KEGG: scb:SCAB_65871 hypothetical protein; SPTR: uncharacterized protein YP_004100268.1 KEGG: nda:Ndas_0033 hypothetical protein; SPTR: uncharacterized protein YP_004100269.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: scb:SCAB_51851 sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004100270.1 InterPro IPR008462; KEGG: aau:AAur_0176 CsbD-like family protein; PFAM: CsbD family protein; SPTR: CsbD family protein; PFAM: CsbD-like YP_004100271.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: pak:HMPREF0675_5011 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004100272.1 COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterPro IPR008332: IPR014048: IPR001497; KEGG: sen:SACE_6024 methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; methylguanine DNA methyltransferase ribonuclease domain protein; SPTR: methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004100273.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: cfl:Cfla_1912 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004100274.1 COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterPro IPR001646: IPR008332: IPR014048: IPR001497; KEGG: amd:AMED_4231 methylated-DNA-[protein]-cysteine S-methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; pentapeptide repeat protein; methylguanine DNA methyltransferase ribonuclease domain protein; SPTR: methylated DNA-protein cysteine methyltransferase-like protein; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Pentapeptide repeats (8 copies); 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004100275.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR007630: IPR014325: IPR014284; KEGG: cai:Caci_8734 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_004100276.1 KEGG: sml:Smlt2003 proline/alanine-rich repetetive membrane anchored protein; SPTR: proline/alanine-rich repetetive membrane anchored protein YP_004100277.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141: IPR017078: IPR004013; KEGG: nca:Noca_1522 hypothetical protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: uncharacterized protein; PFAM: PHP domain YP_004100278.1 KEGG: art:Arth_0193 CdaR family transcriptional regulator; SPTR: CdaR family transcriptional regulator YP_004100279.1 COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR001041: IPR017927: IPR001221: IPR008333: IPR 001433; KEGG: art:Arth_0194 oxidoreductase FAD/NAD(P)-binding subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; ferredoxin; SPTR: oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; oxidoreductase FAD-binding domain; oxidoreductase NAD-binding domain YP_004100280.1 COGs: COG3239 Fatty acid desaturase; InterPro IPR005804; KEGG: art:Arth_0195 fatty acid desaturase; PFAM: fatty acid desaturase; SPTR: Fatty acid desaturase; PFAM: Fatty acid desaturase YP_004100281.1 COGs: COG0560 phosphoserine phosphatase; InterPro IPR005834: IPR006383: IPR006385; KEGG: cwo:Cwoe_4644 HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily subfamily IB hydrolase, TIGR01490; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like YP_004100282.1 COGs: COG0167 dihydroorotate dehydrogenase; InterPro IPR012135; KEGG: mkm:Mkms_4953 dihydroorotate dehydrogenase 2; PFAM: dihydroorotate oxidase; SPTR: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase YP_004100283.1 COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit alpha; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate/ketoisovalerate oxidoreductase, catalytic domain; pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Domain of unknown function; domain; 4Fe-4S binding domain; pyruvate ferredoxin/flavodoxin oxidoreductase; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric YP_004100284.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR017896: IPR013027: IPR000103: IPR017900; KEGG: mva:Mvan_4108 glutamate synthase (NADPH) small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain YP_004100285.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR000644: IPR018529: IPR001093: IPR005991; KEGG: scb:SCAB_75391 inosine monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: inosine monophosphate dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase family protein YP_004100286.1 InterPro IPR006026: IPR001506: IPR007280; KEGG: lch:Lcho_4313 peptidase domain-containing protein; PFAM: peptidase M12A astacin; peptidase domain protein; SMART: peptidase metallopeptidase; SPTR: peptidase domain protein; PFAM: Astacin (peptidase family M12A) YP_004100287.1 KEGG: cai:Caci_0707 hypothetical protein; SPTR: uncharacterized protein YP_004100288.1 COGs: COG2353 conserved hypothetical protein; InterPro IPR007372; KEGG: bcv:Bcav_0089 YceI family protein; PFAM: YceI family protein; SPTR: YceI family protein; PFAM: YceI-like domain YP_004100289.1 InterPro IPR000209: IPR003137; KEGG: ttr:Tter_0669 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; SPTR: peptidase S8 and S53 subtilisin kexin sedolisin; PFAM: PA domain; Subtilase family YP_004100290.1 COGs: COG0602 organic radical activating protein; InterPro IPR012837: IPR007197; KEGG: stp:Strop_1943 hypothetical protein; PFAM: radical SAM domain protein; SPTR: uncharacterized protein; manually curated; PFAM: radical SAM superfamily YP_004100291.1 KEGG: art:Arth_1020 hypothetical protein; SPTR: uncharacterized protein; PFAM: general secretion pathway protein K YP_004100292.1 KEGG: amd:AMED_8499 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2997) YP_004100293.1 KEGG: stp:Strop_1940 hypothetical protein; SPTR: uncharacterized protein YP_004100294.1 COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593: IPR003959; KEGG: stp:Strop_1939 ATPase central domain-containing protein; PFAM: ATPase AAA; SMART: ATPase AAA; SPTR: ATPase AAA, central domain protein; PFAM: ATPase family associated with various cellular activities (AAA) YP_004100295.1 COGs: COG1502 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: ske:Sked_03300 hypothetical protein; SMART: phospholipase D/transphosphatidylase; SPTR: phospholipase D/transphosphatidylase YP_004100296.1 InterPro IPR018973; KEGG: xce:Xcel_2321 hypothetical protein; PFAM: protein of unknown function DUF1998; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1998) YP_004100297.1 InterPro IPR001650; KEGG: xce:Xcel_2322 helicase domain protein; PFAM: helicase; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain YP_004100298.1 InterPro IPR002052: IPR002296; KEGG: nca:Noca_4784 hypothetical protein; SPTR: uncharacterized protein YP_004100299.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014021: IPR001650: IPR014001: IPR000330; KEGG: xce:Xcel_2324 helicase; PFAM: helicase; SNF2-related protein; SMART: DEAD-like helicase; helicase; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004100300.1 KEGG: tel:tll1780 hypothetical protein; SPTR: uncharacterized protein YP_004100301.1 KEGG: mar:MAE_46730 hypothetical protein; SPTR: uncharacterized protein YP_004100302.1 KEGG: cfl:Cfla_3278 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004100303.1 KEGG: cfl:Cfla_3279 hypothetical protein; SPTR: uncharacterized protein YP_004100304.1 InterPro IPR018486: IPR014001: IPR001650; KEGG: cfl:Cfla_3280 helicase; PFAM: helicase; SMART: DEAD-like helicase; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain YP_004100305.1 KEGG: cyn:Cyan7425_5369 hypothetical protein; SPTR: uncharacterized protein YP_004100306.1 InterPro IPR022272; KEGG: scb:SCAB_57561 hypothetical protein; SPTR: uncharacterized protein YP_004100307.1 KEGG: rer:RER_40150 hypothetical protein; SPTR: uncharacterized protein YP_004100308.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) subunit alpha - helicase superfamily I member; InterPro IPR014862; KEGG: xce:Xcel_0849 TrwC relaxase; PFAM: TrwC relaxase; SPTR: TrwC relaxase; PFAM: TrwC relaxase; TIGRFAM: conjugative relaxase domain, TrwC/TraI family YP_004100309.1 KEGG: nca:Noca_2270 hypothetical protein; SPTR: uncharacterized protein YP_004100310.1 KEGG: rca:Rcas_1389 DNA-cytosine methyltransferase; SPTR: DNA-cytosine methyltransferase YP_004100311.1 KEGG: ach:Achl_1172 serine/threonine protein kinase; SPTR: serine/threonine protein kinase YP_004100312.1 KEGG: xce:Xcel_3158 hypothetical protein; SPTR: OSJNBb0050O03.17 protein; manually curated YP_004100313.1 InterPro IPR020084: IPR020476: IPR000086; KEGG: ami:Amir_1278 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004100314.1 InterPro IPR016160; KEGG: sen:SACE_0474 hypothetical protein; SPTR: Stf protein YP_004100315.1 KEGG: lbz:LbrM35_V2.3050 dead/h helicase; SPTR: Pre-mrna splicing factor ATP-dependent RNA helicase, (Dead/h helicase, ) YP_004100316.1 KEGG: syd:Syncc9605_2377 ATPase; SPTR: Regulatory protein YP_004100317.1 KEGG: krh:KRH_07900 hypothetical protein; SPTR: Hypothetical membrane protein YP_004100318.1 COGs: COG0791 cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: sco:SCO3511 lipoprotein; PFAM: NLP/P60 protein; SPTR: Gp133; PFAM: NlpC/P60 family YP_004100319.1 KEGG: xce:Xcel_0821 hypothetical protein; SPTR: uncharacterized protein YP_004100320.1 KEGG: mno:Mnod_1468 FAD linked oxidase domain protein; SPTR: ATP dependent DNA ligase YP_004100321.1 KEGG: kse:Ksed_06740 hypothetical protein; SPTR: uncharacterized protein; PFAM: TrbL/VirB6 plasmid conjugal transfer protein YP_004100322.1 KEGG: kse:Ksed_06750 hypothetical protein; SPTR: uncharacterized protein YP_004100323.1 COGs: COG3451 type IV secretory pathway VirB4 protein; KEGG: mlu:Mlut_00150 hypothetical protein; SPTR: uncharacterized protein YP_004100324.1 COGs: COG3547 transposase and inactivated derivatives; InterPro IPR003346; KEGG: mgi:Mflv_0689 transposase IS116/IS110/IS902 family protein; PFAM: transposase IS116/IS110/IS902 family protein; SPTR: IS110 family transposase; PFAM: transposase IS116/IS110/IS902 family; transposase YP_004100325.1 InterPro IPR003346; KEGG: mva:Mvan_4882 transposase IS116/IS110/IS902 family protein; PFAM: transposase IS116/IS110/IS902 family protein; SPTR: transposase IS116/IS110/IS902 family protein; PFAM: transposase IS116/IS110/IS902 family; transposase YP_004100326.1 InterPro IPR000305; KEGG: bcv:Bcav_0503 hypothetical protein; PFAM: excinuclease ABC subunit C SPTR: uncharacterized protein YP_004100327.1 KEGG: rer:RER_58980 hypothetical protein; SPTR: uncharacterized protein YP_004100328.1 KEGG: vap:Vapar_5798 hypothetical protein; SPTR: uncharacterized protein YP_004100329.1 KEGG: scb:SCAB_5171 hypothetical protein; SPTR: Gp253 YP_004100330.1 KEGG: tcu:Tcur_0780 heat shock protein 70; SPTR: heat shock protein 70 YP_004100331.1 COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: mkm:Mkms_5620 IstB ATP binding domain-containing protein; PFAM: IstB domain protein ATP-binding protein; SMART: ATPase AAA; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004100332.1 COGs: COG4584 transposase and inactivated derivatives; InterPro IPR001584; KEGG: rop:ROP_pROB02-00790 transposase orfA for insertion sequence element; PFAM: Integrase catalytic region; SPTR: transposase orfA for insertion sequence element; PFAM: Integrase core domain YP_004100333.1 KEGG: rha:RHA1_ro06437 hypothetical protein; SPTR: uncharacterized protein YP_004100334.1 COGs: COG3505 type IV secretory pathway VirD4 protein; KEGG: mlu:Mlut_00130 hypothetical protein; SPTR: uncharacterized protein; PFAM: TraG/TraD family YP_004100335.1 KEGG: xce:Xcel_0797 hypothetical protein; SPTR: uncharacterized protein YP_004100336.1 KEGG: rce:RC1_2420 ATP-dependent helicase MgpS; SPTR: ATP-dependent helicase MgpS YP_004100337.1 COGs: COG0358 DNA primase; InterPro IPR002694: IPR013264; KEGG: fra:Francci3_1282 DNA primase; PFAM: DNA primase catalytic core domain; SPTR: DNA primase; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core YP_004100338.1 KEGG: cre:CHLREDRAFT_145982 hypothetical protein; SPTR: uncharacterized protein YP_004100339.1 KEGG: acp:A2cp1_3940 hypothetical protein; SPTR: hypothetical protein YP_004100340.1 InterPro IPR010093; KEGG: scb:SCAB_46971 excisionase; SPTR: Xis; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family YP_004100341.1 InterPro IPR002104; KEGG: aau:AAur_pTC10045 integrase; PFAM: integrase; SPTR: Int; PFAM: Phage integrase family YP_004100342.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: afu:AF2411 hypothetical protein; PFAM: Luciferase-like, subgroup; SPTR: uncharacterized protein; PFAM: Luciferase-like monooxygenase YP_004100343.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR001753; KEGG: sti:Sthe_0823 enoyl-CoA hydratase/isomerase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase/isomerase family protein; PFAM: enoyl-CoA hydratase/isomerase family YP_004100344.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: drm:Dred_0576 crotonobetaine/carnitine-CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme YP_004100345.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149; KEGG: nde:NIDE2776 NAD-dependent alcohol dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: alcohol dehydrogenase zinc-binding domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase YP_004100346.1 COGs: COG1024 enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: svi:Svir_06370 enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase; PFAM: enoyl-CoA hydratase/isomerase family YP_004100347.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904: IPR002347: IPR002198; KEGG: lsp:Bsph_2947 3-oxoacyl-[acyl-carrier-protein] reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004100348.1 COGs: COG0508 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR001078; KEGG: ace:Acel_0588 dehydrogenase catalytic domain-containing protein; PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; PRIAM: dihydrolipoyllysine-residue acetyltransferase; SPTR: Catalytic domain of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain) YP_004100349.1 COGs: COG0508 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR003016: IPR000089; KEGG: rxy:Rxyl_3048 biotin/lipoyl attachment; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: Biotin/lipoyl attachment; PFAM: Biotin-requiring enzyme YP_004100350.1 COGs: COG0022 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit beta; InterPro IPR005475: IPR005476; KEGG: bbr:BB4704A pyruvate dehydrogenase E1 subunit beta; PFAM: transketolase; transketolase domain-containing protein; SPTR: pyruvate dehydrogenase E1 subunit beta; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain YP_004100351.1 COGs: COG1071 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit alpha; InterPro IPR001017; KEGG: tpd:Teth39_0790 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: pyruvate dehydrogenase (acetyl-transferring); SPTR: pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component YP_004100352.1 COGs: COG3777 conserved hypothetical protein; KEGG: mav:MAV_3005 MaoC like domain-containing protein; SPTR: MaoC like domain protein YP_004100353.1 KEGG: rha:RHA1_ro00762 hypothetical protein; SPTR: uncharacterized protein YP_004100354.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: gct:GC56T3_1857 butyryl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004100355.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: cwo:Cwoe_0832 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: TetR family transcriptional regulator; manually curated; PFAM: Bacterial regulatory proteins, tetR family YP_004100356.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: chy:CHY_2228 high affinity branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: High affinity branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004100357.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593; KEGG: gtn:GTNG_1511 branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004100358.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: oih:OB0684 branched-chain amino acid ABC transporter permease; PFAM: inner-membrane translocator; SPTR: Branched-chain amino acid ABC transporter permease; PFAM: Branched-chain amino acid transporter / permease YP_004100359.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: reu:Reut_B3660 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004100360.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR000709: IPR001828; KEGG: gct:GC56T3_1847 extracellular ligand-binding receptor; PFAM: extracellular ligand-binding receptor; SPTR: extracellular ligand-binding receptor YP_004100361.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: amd:AMED_1665 beta-lactamase class B; SPTR: Zn-dependent hydrolase, glyoxylase; PFAM: metallo-beta-lactamase superfamily YP_004100362.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904: IPR002347: IPR002198; KEGG: bpe:BP2854 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004100363.1 KEGG: nml:Namu_1106 hypothetical protein; SPTR: uncharacterized protein YP_004100364.1 KEGG: rer:RER_31510 hypothetical protein; SPTR: uncharacterized protein YP_004100365.1 KEGG: rer:RER_31520 hypothetical protein; SPTR: Prevent-host-death family antitoxin YP_004100366.1 InterPro IPR001647; KEGG: nca:Noca_0220 regulatory protein, TetR; PFAM: regulatory protein TetR; SPTR: Regulatory protein, TetR; manually curated; PFAM: Bacterial regulatory proteins, tetR family YP_004100367.1 InterPro IPR001647; KEGG: nca:Noca_0219 regulatory protein, TetR; PFAM: regulatory protein TetR; SPTR: Regulatory protein, TetR; PFAM: Bacterial regulatory proteins, tetR family YP_004100368.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR014757: IPR002563; KEGG: cgt:cgR_2302 hypothetical protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: uncharacterized protein; PFAM: Flavin reductase like domain YP_004100369.1 COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076; KEGG: nca:Noca_0198 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: FAD dependent oxidoreductase; SPTR: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain YP_004100370.1 KEGG: nca:Noca_0199 hydantoin racemase-like; SPTR: Hydantoin racemase-like; PFAM: Asp/Glu/Hydantoin racemase YP_004100371.1 COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953; KEGG: nca:Noca_0200 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain; TIGRFAM: precorrin 3B synthase CobZ YP_004100372.1 COGs: COG1335 amidase related to nicotinamidase; InterPro IPR000868; KEGG: nca:Noca_0201 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family YP_004100373.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: nca:Noca_0202 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004100374.1 COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953; KEGG: nca:Noca_0203 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain; TIGRFAM: flavocytochrome C YP_004100375.1 COGs: COG2513 PEP phosphonomutase; InterPro IPR000918; KEGG: nca:Noca_0204 2,3-dimethylmalate lyase; PFAM: isocitrate lyase and phosphorylmutase; SPTR: 2,3-dimethylmalate lyase; PFAM: isocitrate lyase family YP_004100376.1 InterPro IPR003006: IPR004360; KEGG: bav:BAV0594 2,3-dihydroxybiphenyl 1,2-dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: extradiol dioxygenase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 2,3-dihydroxybiphenyl 1,2-dioxygenase YP_004100377.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR013107; KEGG: mab:MAB_0075 hydroxylase; PFAM: acyl-CoA dehydrogenase type 2 domain; SPTR: hydroxylase; PFAM: acyl-CoA dehydrogenase, C-terminal domain YP_004100378.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: fre:Franean1_2894 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: Hydrolase; PFAM: alpha/beta hydrolase fold YP_004100379.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR013107; KEGG: mpa:MAP1448c hypothetical protein; PFAM: acyl-CoA dehydrogenase type 2 domain; SPTR: Pigment production hydroxylase; PFAM: acyl-CoA dehydrogenase, C-terminal domain YP_004100380.1 COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: nca:Noca_0101 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004100381.1 COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: nca:Noca_0100 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP binding protein; PFAM: ABC transporter YP_004100382.1 KEGG: nca:Noca_0806 ABC-type sugar transporter periplasmic component-like; SPTR: uncharacterized protein YP_004100383.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: nca:Noca_0210 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold YP_004100384.1 COGs: COG1802 transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: cai:Caci_5914 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004100385.1 COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sgr:SGR_1624 proline racemase; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: Proline racemase; PFAM: Proline racemase YP_004100386.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR017871: IPR003439; KEGG: tbi:Tbis_0408 ABC transporter-like protein; PFAM: ABC transporter related; SPTR: ABC transporter; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004100387.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593; KEGG: sro:Sros_5999 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004100388.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: sro:Sros_6000 branched-chain amino acid transporter permease; PFAM: inner-membrane translocator; SPTR: Branched-chain amino acid transporter permease; PFAM: Branched-chain amino acid transporter / permease YP_004100389.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: sro:Sros_6001 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease YP_004100390.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR000709: IPR001828; KEGG: tbi:Tbis_0404 extracellular ligand-binding receptor; PFAM: extracellular ligand-binding receptor; SPTR: extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004100391.1 COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sco:SCO6293 hypothetical protein; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: 4-hydroxyproline epimerase; PFAM: Proline racemase YP_004100392.1 COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: sco:SCO6292 dihydropicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydropicolinate synthase; PFAM: dihydrodipicolinate synthetase family YP_004100393.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR017224: IPR007419; KEGG: sco:SCO6291 secreted oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: secreted oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S] binding domain YP_004100394.1 KEGG: cai:Caci_5918 hypothetical protein; SPTR: uncharacterized protein YP_004100395.1 COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR000759: IPR006076; KEGG: sco:SCO6289 secreted oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Secreted oxidoreductase; PFAM: FAD dependent oxidoreductase YP_004100396.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ach:Achl_0350 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase family YP_004100397.1 COGs: COG1679 conserved hypothetical protein; InterPro IPR007506; KEGG: bmj:BMULJ_03543 hypothetical protein; PFAM: protein of unknown function DUF521; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF521) YP_004100398.1 COGs: COG1786 conserved hypothetical protein; InterPro IPR002840; KEGG: bac:BamMC406_3637 hypothetical protein; PFAM: protein of unknown function DUF126; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF126 YP_004100399.1 InterPro IPR000182; KEGG: cmi:CMM_0772 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004100400.1 KEGG: tcu:Tcur_0157 hypothetical protein; SPTR: uncharacterized protein YP_004100401.1 KEGG: spo:SPCC1742.01 sequence orphan; SPTR: uncharacterized protein YP_004100402.1 InterPro IPR004360; KEGG: fal:FRAAL4180 hypothetical protein; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004100403.1 COGs: COG0348 polyferredoxin; InterPro IPR017900: IPR017896; KEGG: kol:Kole_0403 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004100404.1 KEGG: aco:Amico_0074 polyferredoxin; SPTR: polyferredoxin YP_004100405.1 COGs: COG1186 protein chain release factor B; InterPro IPR000352; KEGG: nca:Noca_1387 class I peptide chain release factor; PFAM: class I peptide chain release factor; SPTR: peptidyl-tRNA hydrolase domain protein; PFAM: RF-1 domain YP_004100406.1 COGs: COG3662 conserved hypothetical protein; InterPro IPR018713; KEGG: nca:Noca_3952 hypothetical protein; PFAM: protein of unknown function DUF2236; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2236) YP_004100407.1 COGs: COG1171 threonine dehydratase; InterPro IPR005789: IPR001926: IPR002912; KEGG: sma:SAV_3302 threonine dehydratase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; amino acid-binding ACT domain protein; SPTR: threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: ACT domain; pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form YP_004100408.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: rca:Rcas_2645 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase YP_004100409.1 COGs: COG0579 dehydrogenase; InterPro IPR006076; KEGG: svi:Svir_21030 hydroxyglutarate oxidase; PFAM: FAD dependent oxidoreductase; SPTR: Predicted dehydrogenase; PFAM: FAD dependent oxidoreductase YP_004100410.1 COGs: COG3544 conserved hypothetical protein; InterPro IPR005183; KEGG: nfa:nfa38100 hypothetical protein; PFAM: protein of unknown function DUF305; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF305) YP_004100411.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006091: IPR006090; KEGG: ami:Amir_1569 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004100412.1 COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR001828; KEGG: svi:Svir_22980 amino acid-binding protein; PFAM: extracellular ligand-binding receptor; SPTR: Amino acid-binding protein; PFAM: Receptor family ligand binding region YP_004100413.1 COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: svi:Svir_22990 ABC-type branched-chain amino acid transporter permease; PFAM: inner-membrane translocator; SPTR: ABC-type branched-chain amino acid transporter permease; PFAM: Branched-chain amino acid transporter / permease YP_004100414.1 COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR018212: IPR001851; KEGG: svi:Svir_23000 branched-chain amino acid ABC-type transporter permease; PFAM: inner-membrane translocator; SPTR: Branched-chain amino acid ABC-type transporter permease; PFAM: Branched-chain amino acid transporter / permease YP_004100415.1 COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: svi:Svir_23010 ABC-type branched-chain amino acid transporters, ATPase component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type branched-chain amino acid transporters, ATPase component; PFAM: ABC transporter YP_004100416.1 COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003439: IPR003593; KEGG: svi:Svir_23020 ABC-type branched-chain amino acid transporters, ATPase component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type branched-chain amino acid transporters, ATPase component; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004100417.1 KEGG: tcu:Tcur_1477 CdaR family transcriptional regulator; SPTR: CdaR family transcriptional regulator YP_004100418.1 COGs: COG2030 acyl dehydratase; InterPro IPR002539; KEGG: nca:Noca_4109 dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: MaoC domain protein dehydratase; PFAM: MaoC like domain YP_004100419.1 InterPro IPR000620; KEGG: sen:SACE_7083 drug/metabolite transporter (DMT) superfamily protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Drug/metabolite transporter (DMT) superfamily protein; PFAM: EamA-like transporter family YP_004100420.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR000169: IPR006092: IPR006091: IPR006090; KEGG: tbi:Tbis_2866 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004100421.1 COGs: COG3173 aminoglycoside phosphotransferase; InterPro IPR008266: IPR002575; KEGG: nfa:nfa34090 phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: phosphotransferase; PFAM: phosphotransferase enzyme family YP_004100422.1 COGs: COG2030 acyl dehydratase; InterPro IPR002539; KEGG: svi:Svir_16780 acyl dehydratase; PFAM: MaoC domain protein dehydratase; PRIAM: enoyl-CoA hydratase; SPTR: acyl dehydratase; PFAM: MaoC like domain YP_004100423.1 COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904: IPR002347: IPR002198; KEGG: nfa:nfa23600 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: short chain dehydrogenase; PFAM: short chain dehydrogenase YP_004100424.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR020904: IPR002347: IPR002198; KEGG: nca:Noca_1829 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004100425.1 COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR000977: IPR012309; KEGG: nca:Noca_2845 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; PRIAM: DNA ligase (ATP); SPTR: Probable DNA ligase; TIGRFAM: DNA ligase I, ATP-dependent Dnl1; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase I, ATP-dependent (dnl1) YP_004100426.1 COGs: COG0189 glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR011761: IPR004218; KEGG: kse:Ksed_05120 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; PRIAM: glutathione synthase; SPTR: glutathione synthetase; PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic YP_004100427.1 COGs: COG3930 conserved hypothetical protein; InterPro IPR012548; KEGG: paa:Paes_0605 protein of unknown function DUF1704; PFAM: protein of unknown function DUF1704; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1704); TIGRFAM: conserved hypothetical protein YP_004100428.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR006589: IPR004193: IPR006047: IPR006048; KEGG: mes:Meso_2421 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; SPTR: 1,4-alpha-glucan branching enzyme; PFAM: alpha amylase, C-terminal all-beta domain; alpha amylase, catalytic domain; carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: malto-oligosyltrehalose trehalohydrolase YP_004100429.1 COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: kfl:Kfla_2551 D-amino-acid dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: D-amino-acid dehydrogenase; PFAM: FAD dependent oxidoreductase YP_004100430.1 COGs: COG2508 Regulator of polyketide synthase expression; KEGG: kfl:Kfla_2550 PucR family transcriptional regulator; SPTR: PucR family transcriptional regulator YP_004100431.1 COGs: COG1247 Sortase and related acyltransferase; InterPro IPR000182; KEGG: scb:SCAB_23771 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5 N-acetyltransferase; manually curated; PFAM: acetyltransferase (GNAT) family YP_004100432.1 InterPro IPR004360; KEGG: ach:Achl_2048 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004100433.1 InterPro IPR010093: IPR000551; KEGG: tbi:Tbis_3348 excisionase family DNA binding domain-containing protein; PFAM: regulatory protein MerR; SPTR: Excisionase/Xis, DNA-binding; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: MerR family regulatory protein; TIGRFAM: DNA binding domain, excisionase family YP_004100434.1 KEGG: kse:Ksed_06070 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3073) YP_004100435.1 COGs: COG0150 phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733: IPR000728: IPR010918; KEGG: ske:Sked_34080 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: phosphoribosylformylglycinamidine cyclo-ligase; SPTR: phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase YP_004100436.1 KEGG: nca:Noca_0019 hypothetical protein; SPTR: uncharacterized protein YP_004100437.1 COGs: COG0034 glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR017932: IPR005854: IPR000583: IPR000836; KEGG: cfl:Cfla_2908 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; phosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: amidophosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase YP_004100438.1 COGs: COG1514 2'-5' RNA ligase; InterPro IPR004175: IPR014051; KEGG: nca:Noca_0273 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; SPTR: uncharacterized protein; TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase family; TIGRFAM: 2'-5' RNA ligase YP_004100439.1 KEGG: ske:Sked_34100 hypothetical protein; SPTR: uncharacterized protein YP_004100440.1 InterPro IPR000412: IPR013526: IPR013525; KEGG: kse:Ksed_25220 ABC-type polysaccharide/polyol phosphate export systems, permease; PFAM: ABC transporter; SPTR: ABC-type polysaccharide/polyol phosphate export systems, permease; PFAM: ABC transporter; TIGRFAM: ABC transporter NodJ family YP_004100441.1 InterPro IPR000412: IPR013526: IPR013525; KEGG: kse:Ksed_25210 ABC-type multidrug transporter permease; PFAM: ABC transporter; SPTR: ABC-type multidrug transporter permease; PFAM: ABC transporter YP_004100442.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR017871: IPR003439: IPR015851: IPR003593; KEGG: kse:Ksed_25200 ABC-type multidrug transporter ATPase component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter, ATPase component; PFAM: ABC transporter; TIGRFAM: ATP-binding ABC transporter family nodulation protein NodI YP_004100443.1 KEGG: art:Arth_3409 hypothetical protein; SPTR: uncharacterized protein YP_004100444.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: amd:AMED_0222 luciferase family protein; PFAM: Luciferase-like, subgroup; SPTR: uncharacterized protein; PFAM: Luciferase-like monooxygenase YP_004100445.1 KEGG: kse:Ksed_06000 hypothetical protein; SPTR: Conserved protein ( spermidine synthase) YP_004100446.1 COGs: COG4867 Uncharacterized protein with a von Willebrand factor A (vWA) domain; InterPro IPR002035; KEGG: nca:Noca_0953 von Willebrand factor, type A; SMART: von Willebrand factor A; SPTR: von Willebrand factor, type A YP_004100447.1 COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: nca:Noca_0952 magnesium chelatase subunit ChlI; SPTR: magnesium chelatase subunit ChlI YP_004100448.1 InterPro IPR010195: IPR003779; KEGG: msv:Mesil_1021 peroxidase; PFAM: carboxymuconolactone decarboxylase; SPTR: uncharacterized protein; TIGRFAM: peroxidase; PFAM: carboxymuconolactone decarboxylase family; TIGRFAM: peroxidase; alkylhydroperoxidase AhpD family core domain YP_004100449.1 KEGG: bml:BMA10229_A0775 permease; SPTR: ABC lysophospholipase exporter, fused innermembrane subunits, FtsX YP_004100450.1 COGs: COG0046 phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR017926: IPR010073: IPR000728: IPR010918; KEGG: mpt:Mpe_A1761 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: phosphoribosylformylglycinamidine synthase; SPTR: phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, single chain form YP_004100451.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179: IPR004843: IPR008334; KEGG: sna:Snas_4270 5'-nucleotidase domain-containing protein; PFAM: 5'-nucleotidase domain-containing protein; metallophosphoesterase; SPTR: 5'-nucleotidase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain YP_004100452.1 KEGG: kfl:Kfla_3129 hypothetical protein; SPTR: uncharacterized protein YP_004100453.1 COGs: COG0152 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636; KEGG: tcu:Tcur_0194 phosphoribosylaminoimidazole-succinocarboxamides ynthase; PFAM: SAICAR synthetase; PRIAM: phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004100454.1 COGs: COG0151 phosphoribosylamine-glycine ligase; InterProIPR011761: IPR011764: IPR000115: IPR020562: IPR 020561: IPR020560; KEGG: xce:Xcel_3134 phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; phosphoribosylglycinamide synthetase, N-domain; phosphoribosylglycinamide synthetase, C-domain; PRIAM: phosphoribosylamine--glycine ligase; SPTR: phosphoribosylglycinamide synthetase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase, N domain; phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase YP_004100455.1 COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; KEGG: nml:Namu_4157 acetyltransferase including N-acetylase of ribosomal protein-like protein; SPTR: acetyltransferase including N-acetylase of ribosomal protein-like protein YP_004100456.1 COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR014016; KEGG: kse:Ksed_05760 DNA/RNA helicase, superfamily I; SPTR: helicase protein; manually curated; PFAM: UvrD/REP helicase YP_004100457.1 COGs: COG1384 Lysyl-tRNA synthetase (class I); InterPro IPR001412: IPR002904: IPR020756: IPR020754; KEGG: scb:SCAB_38941 lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase, class Ic; PRIAM: lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete YP_004100458.1 COGs: COG0104 adenylosuccinate synthase; InterPro IPR018220: IPR001114; KEGG: nca:Noca_4344 adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; PRIAM: adenylosuccinate synthase; SMART: adenylosuccinate synthetase; SPTR: adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase YP_004100459.1 KEGG: rpc:RPC_2995 lytic transglycosylase, catalytic; SPTR: glutamate 5-kinase YP_004100460.1 KEGG: mva:Mvan_1118 hypothetical protein; SPTR: uncharacterized protein YP_004100461.1 KEGG: ami:Amir_5156 short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein YP_004100462.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: art:Arth_0139 diacylglycerol kinase, catalytic region; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase; SPTR: diacylglycerol kinase, catalytic region; manually curated; PFAM: diacylglycerol kinase catalytic domain YP_004100463.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: sna:Snas_6338 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004100464.1 InterPro IPR004360; KEGG: sco:SCO6519 lyase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lyase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004100465.1 KEGG: nml:Namu_1430 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104) YP_004100466.1 COGs: COG3324 protein related to lactoylglutathione lyase; InterPro IPR004360; KEGG: pjd:Pjdr2_0218 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase YP_004100467.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR012318: IPR001808; KEGG: xce:Xcel_1838 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Crp/Fnr family transcriptional regulator; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_004100468.1 COGs: COG1080 phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR006318: IPR008731: IPR008279: IPR000121; KEGG: ahe:Arch_1460 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; SPTR: phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase YP_004100469.1 COGs: COG1925 phosphotransferase system HPr-related protein; InterPro IPR001020: IPR000032: IPR005698; KEGG: cmi:CMM_1505 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: phosphotransferase System HPr (HPr) Family YP_004100470.1 COGs: COG1299 phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIsubunit alpha; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system, EIIC; PTS system, Lactose/cellobiose specific IIB subunit; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component; PTS system, fructose subfamily, IIA component; TC 4.A.2.1.4 YP_004100471.1 COGs: COG1105 fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR002173: IPR017583: IPR011611; KEGG: sen:SACE_2273 6-phosphofructokinase; PFAM: PfkB domain protein; PRIAM: 1-phosphofructokinase; SPTR: 6-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family YP_004100472.1 COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001969: IPR001034: IPR014036; KEGG: saq:Sare_4851 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004100473.1 InterPro IPR019920: IPR011576; KEGG: rha:RHA1_ro04083 hypothetical protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: uncharacterized protein; TIGRFAM: F420-dependent enzyme; PFAM: pyridoxamine 5'-phosphate oxidase; TIGRFAM: PPOX class probable F420-dependent enzyme YP_004100474.1 InterPro IPR014487; KEGG: kse:Ksed_05660 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3151) YP_004100475.1 COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR006411; KEGG: nca:Noca_4350 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Ketose-bisphosphate aldolase, class-II:fructose-bisphosphate aldolase, class II; TIGRFAM: fructose-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-bisphosphate aldolase, class II, yeast/E. coli subtype YP_004100476.1 COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: tcu:Tcur_3392 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase YP_004100477.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR017871: IPR001131: IPR000994; KEGG: amd:AMED_4873 X-Pro dipeptidase; PFAM: peptidase M24; SPTR: peptidase M24; PFAM: metallopeptidase family M24; Creatinase/Prolidase N-terminal domain YP_004100478.1 COGs: COG3360 conserved hypothetical protein; InterPro IPR009923; KEGG: ach:Achl_0494 protein of unknown function DUF1458; PFAM: protein of unknown function DUF1458; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1458) YP_004100479.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: tfu:Tfu_2449 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: TRNA/rRNA methyltransferase; PFAM: SpoU rRNA methylase family YP_004100480.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: nca:Noca_4353 DedA family membrane protein; PFAM: SNARE associated Golgi protein; SPTR: Conserved membrane protein (DedA family protein); manually curated; PFAM: SNARE associated Golgi protein YP_004100481.1 InterPro IPR001917: IPR017909: IPR013222: IPR005152; KEGG: amd:AMED_9107 lipase; PFAM: secretory lipase; glycosyl hydrolase family 98 carbohydrate binding module; PRIAM: Triacylglycerol lipase; SMART: glycosyl hydrolase family 98 carbohydrate binding module; SPTR: acetyl esterase (Deacetylase); PFAM: NPCBM/NEW2 domain; Secretory lipase YP_004100482.1 InterPro IPR011659; KEGG: hau:Haur_4532 serine/threonine protein kinase; SPTR: protein tolB; PFAM: WD40-like beta Propeller Repeat YP_004100483.1 COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: bcv:Bcav_3645 LemA family protein; PFAM: LemA family protein; SPTR: LemA family protein; PFAM: LemA family YP_004100484.1 COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR000836; KEGG: scb:SCAB_42171 orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase YP_004100485.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198; KEGG: ske:Sked_35320 short-chain dehydrogenase of unknown substrate specificity; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short chain dehydrogenase; PFAM: short chain dehydrogenase YP_004100486.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: mlu:Mlut_15920 predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold; SPTR: Predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold YP_004100487.1 COGs: COG0708 exonuclease III; InterPro IPR004808: IPR000097: IPR005135; KEGG: tfu:Tfu_0258 exodeoxyribonuclease III; PFAM: endonuclease/exonuclease/phosphatase; SPTR: exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: endonuclease/exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_004100488.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: kfl:Kfla_3451 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Aminoglycosides/tetracycline-transport integral membrane protein; PFAM: Major Facilitator Superfamily YP_004100489.1 InterPro IPR009830; KEGG: nca:Noca_2950 hypothetical protein; PFAM: protein of unknown function DUF1396; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1396) YP_004100490.1 KEGG: dvi:Dvir_GJ12577 GJ12577 gene product from transcript GJ12577-RA; SPTR: uncharacterized protein YP_004100491.1 COGs: COG3629 DNA-binding transcriptional activator of the SARP family; InterProIPR019775: IPR019782: IPR017986: IPR001680: IPR 001867: IPR005158; KEGG: nml:Namu_2911 SARP family transcriptional regulator; PFAM: transcriptional activator domain; transcriptional regulator domain-containing protein; SPTR: SARP family transcriptional regulator; PFAM: Bacterial transcriptional activator domain; transcriptional regulatory protein, C terminal YP_004100492.1 KEGG: nml:Namu_0440 peptidase M15B and M15C dd-carboxypeptidase VanY/endolysin; SPTR: ABC-type transporter substrate-binding protein YP_004100493.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR018368: IPR001270: IPR017730: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: xce:Xcel_3161 ATP-dependent chaperone ClpB; PFAM: ATPase AAA; ATPase AAA; Clp domain protein; Clp ATPase-like; SMART: ATPase AAA; SPTR: ATP-dependent protease ATP-binding subunit; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_004100494.1 InterPro IPR001173; KEGG: kse:Ksed_26800 glycosyl transferase; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase; PFAM: glycosyl transferase family 2 YP_004100495.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: kse:Ksed_26810 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004100496.1 KEGG: fre:Franean1_2952 ABC transporter; SPTR: ABC transporter related YP_004100497.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: kse:Ksed_26820 predicted acyltransferase; PFAM: acyltransferase 3; SPTR: Predicted acyltransferase; manually curated; PFAM: acyltransferase family YP_004100498.1 COGs: COG4641 conserved hypothetical protein; InterPro IPR001173; KEGG: kse:Ksed_26830 hypothetical protein; PFAM: glycosyl transferase family 2; SPTR: Uncharacterized conserved protein; PFAM: glycosyl transferase family 2 YP_004100499.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: kse:Ksed_26850 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004100500.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterProIPR016160: IPR017476: IPR001732: IPR014026: IPR 014027; KEGG: kse:Ksed_26760 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004100501.1 COGs: COG1682 ABC-type polysaccharide/polyol phosphate export systems permease; InterPro IPR000412: IPR013525; KEGG: kse:Ksed_26770 ABC-type polysaccharide/polyol phosphate export systems, permease; PFAM: ABC transporter; SPTR: ABC-type polysaccharide/polyol phosphate export systems, permease; PFAM: ABC transporter YP_004100502.1 COGs: COG1134 ABC-type polysaccharide/polyol phosphate transporter ATPase component; InterPro IPR003439: IPR003593; KEGG: jde:Jden_1845 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004100503.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: nda:Ndas_3853 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004100504.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: ske:Sked_08800 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004100505.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: krh:KRH_12670 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004100506.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: kra:Krad_4230 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: transcriptional regulator; PFAM: MerR family regulatory protein YP_004100507.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR018260: IPR018253: IPR001623: IPR003095: IPR 002939; KEGG: kra:Krad_4231 chaperone DnaJ domain protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: DnaJ protein; PFAM: DnaJ C terminal region; DnaJ domain YP_004100508.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: kse:Ksed_05500 molecular chaperone GrpE (heat shock protein); PFAM: GrpE protein; SPTR: protein grpE; PFAM: GrpE YP_004100509.1 COGs: COG0443 Molecular chaperone; InterPro IPR018181: IPR001023: IPR012725: IPR013126; KEGG: kse:Ksed_05490 chaperone protein DnaK; PFAM: heat shock protein 70; SPTR: Chaperone protein dnaK; TIGRFAM: chaperone protein DnaK; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_004100510.1 InterPro IPR007419; KEGG: sli:Slin_5401 molybdopterin oxidoreductase; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: Molybdopterin oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain YP_004100511.1 COGs: COG2193 Bacterioferritin (cytochrome b1); InterPro IPR009040: IPR002024: IPR008331; KEGG: afw:Anae109_2242 bacterioferritin; PFAM: ferritin; SPTR: Bacterioferritin; TIGRFAM: bacterioferritin; PFAM: Ferritin-like domain; TIGRFAM: bacterioferritin YP_004100512.1 KEGG: msl:Msil_1758 hypothetical protein; SPTR: Oxygenase YP_004100513.1 InterPro IPR018062: IPR001296; KEGG: kse:Ksed_26690 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004100514.1 InterPro IPR004193; KEGG: nca:Noca_2674 hypothetical protein; PFAM: glycoside hydrolase family 13 domain protein; SPTR: uncharacterized protein; PFAM: PhoD-like phosphatase YP_004100515.1 COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36 YP_004100516.1 COGs: COG1522 transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: nca:Noca_3944 AsnC family transcriptional regulator; PFAM: transcription regulator AsnC-type-like; SMART: transcription regulator AsnC-type; SPTR: Possible transcriptional regulatory protein (Probably lrp/asnc-family protein); PFAM: IclR helix-turn-helix domain; AsnC family YP_004100517.1 COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_3943 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004100518.1 COGs: COG4425 membrane protein; InterPro IPR012037; KEGG: rop:ROP_35030 hypothetical membrane protein; PFAM: Uncharacterised conserved protein UCP007542; SPTR: Hypothetical membrane protein; PFAM: Predicted membrane protein (DUF2319) YP_004100519.1 COGs: COG2761 dithiol-disulfide isomerase involved in polyketide biosynthesis; InterPro IPR001853; KEGG: rmu:RMDY18_09110 predicted dithiol-disulfide isomerase involved in polyketide biosynthesis; PFAM: DSBA oxidoreductase; SPTR: protein disulfide isomerase (S-S rearrangase); PFAM: DSBA-like thioredoxin domain YP_004100520.1 KEGG: gbr:Gbro_3252 hypothetical protein; SPTR: phosphoribosylglycinamide formyltransferase; PFAM: protein of unknown function (DUF419) YP_004100521.1 COGs: COG2045 phosphosulfolactate phosphohydrolase; KEGG: tpr:Tpau_2411 hypothetical protein; SPTR: uncharacterized protein; PFAM: 2-phosphosulpholactate phosphatase YP_004100522.1 COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: nca:Noca_0622 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase YP_004100523.1 COGs: COG0001 glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: nca:Noca_3921 aminotransferase; PFAM: aminotransferase class-III; SPTR: Aminotransferase; PFAM: Aminotransferase class-III YP_004100524.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: nca:Noca_3653 2-nitropropane dioxygenase, NPD; PFAM: 2-nitropropane dioxygenase NPD; SPTR: 2-nitropropane dioxygenase, NPD; PFAM: 2-nitropropane dioxygenase YP_004100525.1 COGs: COG0039 malate/lactate dehydrogenase; InterPro IPR018177: IPR001557: IPR011304: IPR001236; KEGG: cfl:Cfla_1564 L-lactate dehydrogenase; PFAM: lactate/malate dehydrogenase; SPTR: L-lactate dehydrogenase; TIGRFAM: L-lactate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: L-lactate dehydrogenase YP_004100526.1 InterPro IPR001647; KEGG: rso:RS03880 transcription regulator protein; PFAM: regulatory protein TetR; SPTR: transcription regulator protein; PFAM: Bacterial regulatory proteins, tetR family YP_004100527.1 KEGG: aau:AAur_2321 hypothetical protein; SPTR: uncharacterized protein YP_004100528.1 KEGG: mth:MTH1068 hypothetical protein; SPTR: nucleoside-triphosphatase THEP1 YP_004100529.1 COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: sma:SAV_2602 hypothetical protein; PFAM: OsmC family protein; SPTR: OsmC family protein; PFAM: OsmC-like protein YP_004100530.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019949: IPR016048; KEGG: cwo:Cwoe_3321 luciferase family oxidoreductase, group 1; PFAM: Luciferase-like, subgroup; SPTR: Luciferase family oxidoreductase, group 1; TIGRFAM: luciferase family oxidoreductase, group 1; PFAM: Luciferase-like monooxygenase; TIGRFAM: luciferase family oxidoreductase, group 1 YP_004100532.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839; KEGG: tcu:Tcur_1565 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II YP_004100533.1 KEGG: saq:Sare_3577 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2029) YP_004100534.1 COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR001345: IPR013078; KEGG: aau:AAur_3898 phosphoglycerate mutase family protein; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase family protein; PFAM: phosphoglycerate mutase family YP_004100535.1 KEGG: lbz:LbrM15_V2.1240 cysteine peptidase, Clan CA, family C19; SPTR: uncharacterized protein YP_004100536.1 COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterPro IPR017871: IPR003439: IPR003593: IPR003339; KEGG: bfa:Bfae_11750 ATPase component of various ABC-type transporters with duplicated ATPase domain; PFAM: ABC transporter related; cobalt transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; Cobalt transporter YP_004100537.1 COGs: COG4721 membrane protein; InterPro IPR017195; KEGG: kra:Krad_4237 ABC transporter permease; PFAM: ABC-type thiamin-related transporter permease 1, predicted; SPTR: ABC transporter permease; PFAM: ABC-type cobalt transporter permease YP_004100538.1 KEGG: nca:Noca_2910 hypothetical protein; SPTR: uncharacterized protein YP_004100539.1 InterPro IPR015035; KEGG: cai:Caci_1558 hypothetical protein; PFAM: Domain of unknown function DUF1918; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1918) YP_004100540.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR018274: IPR010121: IPR002192: IPR008279: IPR 000121; KEGG: tfu:Tfu_0863 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: pyruvate, phosphate dikinase; SPTR: pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase YP_004100541.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: nca:Noca_0992 regulatory protein, LuxR; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: two-component system response transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004100542.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018: IPR011712: IPR003594; KEGG: saq:Sare_1529 GAF sensor signal transduction histidine kinase; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: histidine kinase; GAF domain YP_004100543.1 InterPro IPR015057: IPR015035; KEGG: xce:Xcel_0903 hypothetical protein; PFAM: Domain of unknown function DUF1918; Domain of unknown function DUF1876; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1876); Domain of unknown function (DUF1918) YP_004100544.1 COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR005920: IPR006680; KEGG: bcv:Bcav_1839 imidazolonepropionase; PFAM: amidohydrolase; PRIAM: Imidazolonepropionase; SPTR: chlorohydrolase; TIGRFAM: imidazolonepropionase; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase YP_004100545.1 COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR010252: IPR006680; KEGG: nml:Namu_0039 formiminoglutamate deiminase; PFAM: amidohydrolase; SPTR: Formiminoglutamate deiminase; TIGRFAM: formiminoglutamate deiminase; PFAM: Amidohydrolase family; TIGRFAM: formiminoglutamate deiminase YP_004100546.1 COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010158: IPR002933; KEGG: sro:Sros_1779 allantoate amidohydrolase; PFAM: peptidase M20; SPTR: amino acid hydrolase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase family M20/M25/M40; TIGRFAM: amidase, hydantoinase/carbamoylase family YP_004100547.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: cai:Caci_4723 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004100548.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: nca:Noca_2641 YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein YP_004100549.1 COGs: COG2987 Urocanate hydratase; InterPro IPR000193; KEGG: nml:Namu_0040 urocanate hydratase; PFAM: Urocanase; PRIAM: Urocanate hydratase; SPTR: Urocanate hydratase; TIGRFAM: urocanate hydratase; PFAM: Urocanase; TIGRFAM: urocanate hydratase YP_004100550.1 COGs: COG2986 histidine ammonia-lyase; InterPro IPR001106: IPR005921; KEGG: nfa:nfa12280 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: histidine ammonia-lyase; SPTR: histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase YP_004100551.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: krh:KRH_22930 IclR family transcriptional regulator; PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: IclR family transcriptional regulator protein; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004100552.1 KEGG: cmi:CMM_1462 hypothetical protein; SPTR: membrane protein YP_004100553.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR014189: IPR013154: IPR013149; KEGG: sma:SAV_4368 quinone oxidoreductase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: quinone oxidoreductase; TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family YP_004100554.1 COGs: COG3211 phosphatase; InterProIPR022272: IPR017909: IPR006311: IPR019546: IPR 008557; KEGG: kse:Ksed_21970 predicted phosphatase; PFAM: protein of unknown function DUF839; Twin-arginine translocation pathway, signal sequence, subgroup; SPTR: uncharacterized protein; PFAM: TAT (twin-arginine translocation) pathway signal sequence; Bacterial protein of unknown function (DUF839) YP_004100555.1 KEGG: nml:Namu_3002 hypothetical protein; SPTR: uncharacterized protein YP_004100556.1 COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467: IPR004358: IPR003594: IPR017205: IPR 011712; KEGG: sco:SCO1369 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: Probable two component system histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004100557.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: lxx:Lxx07500 two-component system, regulatory protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: LuxR family DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004100558.1 InterPro IPR019695; KEGG: kra:Krad_0259 hypothetical protein; PFAM: protein of unknown function DUF2587; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2587) YP_004100559.1 InterPro IPR004843; KEGG: bfa:Bfae_11330 predicted phosphohydrolase; PFAM: metallophosphoesterase; SPTR: integral membrane protein; PFAM: Calcineurin-like phosphoesterase YP_004100560.1 InterPro IPR005182; KEGG: gob:Gobs_4362 membrane-flanked domain protein; PFAM: membrane-flanked domain; SPTR: membrane-flanked domain protein; PFAM: Bacterial membrane flanked domain YP_004100561.1 COGs: COG2818 3-methyladenine DNA glycosylase; InterPro IPR005019; KEGG: ach:Achl_0015 DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase; PRIAM: DNA-3-methyladenine glycosylase I; SPTR: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase I YP_004100562.1 COGs: COG2808 transcriptional regulator; InterPro IPR018506: IPR007396: IPR011576; KEGG: cfl:Cfla_0243 FMN-binding negative transcriptional regulator; PFAM: negative transcriptional regulator; pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: transcription antitermination factor NusB; PFAM: FMN-binding domain YP_004100563.1 InterPro IPR000326; KEGG: cmi:CMM_0208 membrane-associated phospholipid phosphatase; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004100564.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: rha:RHA1_ro05034 hypothetical protein; SPTR: Multidrug resistance protein RomA YP_004100565.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: nfa:nfa6750 hypothetical protein; SPTR: Multidrug resistance protein RomA YP_004100566.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR003660: IPR004358: IPR003661: IPR 003594; KEGG: stp:Strop_2131 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Two-component system, sensor protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004100567.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR005829: IPR001789: IPR001867; KEGG: sma:SAV_4198 two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: two component system response regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004100568.1 COGs: COG1814 Uncharacterized membrane protein; InterPro IPR008217; KEGG: sma:SAV_6445 hypothetical protein; PFAM: protein of unknown function DUF125 transmembrane; SPTR: uncharacterized protein; PFAM: VIT family YP_004100569.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014021: IPR001650: IPR014001: IPR000330; KEGG: lxx:Lxx07490 ATP-dependent RNA helicase; PFAM: helicase; SNF2-related protein; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004100570.1 InterPro IPR006650; KEGG: sen:SACE_2920 hypothetical protein; SPTR: uncharacterized protein YP_004100571.1 COGs: COG0171 NAD synthase; InterPro IPR003010: IPR003694: IPR014445; KEGG: nca:Noca_2044 NAD synthetase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: NAD+ synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase YP_004100572.1 InterPro IPR011576; KEGG: cur:cur_0523 hypothetical protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: uncharacterized protein; PFAM: pyridoxamine 5'-phosphate oxidase YP_004100573.1 COGs: COG1275 Tellurite resistance protein and related permease; InterPro IPR004695; KEGG: nca:Noca_3979 C4-dicarboxylate transporter/malic acid transporter; PFAM: C4-dicarboxylate transporter/malic acid transporter; SPTR: C4-dicarboxylate transporter/malic acid transporter; PFAM: C4-dicarboxylate transporter/malic acid transporter YP_004100574.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR001917: IPR011282: IPR004839; KEGG: nca:Noca_3756 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: aminotransferase class I and II; PRIAM: glycine C-acetyltransferase; SPTR: 2-amino-3-oxobutyrate:CoA ligase; TIGRFAM: 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; 2-amino-3-ketobutyrate coenzyme A ligase YP_004100575.1 InterPro IPR019967: IPR011576; KEGG: svi:Svir_19860 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: pyridoxamine 5'-phosphate oxidase family protein; TIGRFAM: F420-dependent enzyme; PFAM: pyridoxamine 5'-phosphate oxidase; TIGRFAM: PPOX class probable F420-dependent enzyme, Rv0121 family YP_004100576.1 KEGG: kse:Ksed_04980 predicted hydrolase or acyltransferase of alpha/beta superfamily; SPTR: Predicted hydrolase or acyltransferase of alpha/beta superfamily YP_004100577.1 COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328: IPR013154: IPR013149; KEGG: nca:Noca_3757 L-threonine 3-dehydrogenase; PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; SPTR: L-threonine 3-dehydrogenase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: L-threonine 3-dehydrogenase; 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase YP_004100578.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: kfl:Kfla_0582 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: ferric uptake regulator, Fur family; PFAM: ferric uptake regulator family YP_004100579.1 InterPro IPR000182; KEGG: kfl:Kfla_4864 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004100580.1 KEGG: nmu:Nmul_A1250 hypothetical protein; SPTR: uncharacterized protein YP_004100581.1 KEGG: ami:Amir_6026 hypothetical protein; SPTR: uncharacterized protein YP_004100582.1 InterPro IPR013525; KEGG: saq:Sare_4005 ABC-2 type transporter; PFAM: ABC transporter; SPTR: ABC transporter; PFAM: ABC transporter YP_004100583.1 COGs: COG0605 superoxide dismutase; InterPro IPR019833: IPR001189: IPR019831: IPR019832; KEGG: rha:RHA1_ro04009 superoxide dismutase; PFAM: Manganese/iron superoxide dismutase-like; SPTR: superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain YP_004100584.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterProIPR007527: IPR014021: IPR001650: IPR014001: IPR 000330; KEGG: pfr:PFREUD_00710 helicase (SNF2-related protein); PFAM: SNF2-related protein; helicase; SMART: DEAD-like helicase; helicase; SPTR: SNF2-like; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004100585.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: nca:Noca_3005 luciferase family protein; PFAM: Luciferase-like, subgroup; SPTR: Luciferase family protein; PFAM: Luciferase-like monooxygenase YP_004100586.1 COGs: COG3797 conserved hypothetical protein; InterPro IPR012545; KEGG: nca:Noca_1298 hypothetical protein; PFAM: protein of unknown function DUF1697; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1697) YP_004100587.1 COGs: COG0824 thioesterase; InterPro IPR006683; KEGG: rha:RHA1_ro02740 thioesterase; PFAM: thioesterase superfamily protein; SPTR: thioesterase; PFAM: thioesterase YP_004100588.1 KEGG: nca:Noca_4162 hypothetical protein; SPTR: uncharacterized protein YP_004100589.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR002364: IPR013154: IPR013149; KEGG: svi:Svir_23320 Zn-dependent oxidoreductase, NADPH:quinone reductase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: Zn-dependent oxidoreductase, NADPH:quinone reductase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004100590.1 COGs: COG1085 Galactose-1-phosphate uridylyltransferase; KEGG: mlu:Mlut_15870 hypothetical protein; SPTR: uncharacterized protein YP_004100591.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155: IPR004792: IPR013027; KEGG: kfl:Kfla_5848 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; HI0933 family protein; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family YP_004100592.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: ami:Amir_2311 luciferase-like monooxygenase; PFAM: Luciferase-like, subgroup; SPTR: Luciferase-like monooxygenase; PFAM: Luciferase-like monooxygenase; TIGRFAM: probable oxidoreductase, LLM family YP_004100593.1 COGs: COG3402 conserved hypothetical protein; InterPro IPR005182: IPR018313; KEGG: ami:Amir_1064 membrane-flanked domain protein; PFAM: membrane-flanked domain; SPTR: membrane-flanked domain protein; PFAM: Bacterial membrane flanked domain YP_004100594.1 COGs: COG3428 membrane protein; InterPro IPR005182; KEGG: tbi:Tbis_0853 hypothetical protein; PFAM: membrane-flanked domain; SPTR: membrane-flanked domain protein; PFAM: Bacterial membrane flanked domain YP_004100595.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068: IPR010916; KEGG: pac:PPA0737 18 kDa antigen 2; PFAM: heat shock protein Hsp20; SPTR: 18 kDa antigen 2; PFAM: Hsp20/alpha crystallin family YP_004100596.1 COGs: COG2154 Pterin-4a-carbinolamine dehydratase; InterPro IPR001533; KEGG: kfl:Kfla_1145 hypothetical protein; PFAM: transcriptional coactivator/pterin dehydratase; SPTR: uncharacterized protein; PFAM: Pterin 4 alpha carbinolamine dehydratase YP_004100597.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: sro:Sros_3870 sodium:dicarboxylate symporter; PFAM: sodium:dicarboxylate symporter; SPTR: sodium:dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter family YP_004100598.1 COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; InterProIPR013656: IPR003594: IPR005467: IPR000014: IPR 004358; KEGG: scb:SCAB_28081 two-component sensor kinase; PFAM: ATP-binding region ATPase domain protein; hypothetical protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: two-component sensor kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box YP_004100599.1 COGs: COG4565 Response regulator of citrate/malate metabolism; InterPro IPR001789; KEGG: gob:Gobs_2259 response regulator receiver and unknown domain protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain YP_004100600.1 COGs: COG0663 carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: mjl:Mjls_4306 carbonic anhydrase; SPTR: carbonic anhydrases/acetyltransferases isoleucine patch superfamily-like protein YP_004100601.1 COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: sma:SAV_4105 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR-family transcriptional regulator; PFAM: MarR family YP_004100602.1 InterPro IPR011701; KEGG: scb:SCAB_49161 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: integral membrane protein; PFAM: Major Facilitator Superfamily YP_004100603.1 KEGG: scb:SCAB_75571 hypothetical protein; SPTR: uncharacterized protein YP_004100604.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176: IPR004838; KEGG: bcv:Bcav_2006 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, class I/II; PFAM: Aminotransferase class I and II YP_004100605.1 InterPro IPR019587; KEGG: aau:AAur_3688 hypothetical protein; PFAM: polyketide cyclase/dehydrase; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport YP_004100606.1 COGs: COG2116 formate/nitrite family of transporter; InterPro IPR000292; KEGG: ebi:EbC_14980 probable formate transporter; PFAM: formate/nitrite transporter; SPTR: FNT family formate-nitrite transporter; TIGRFAM: formate/nitrite transporter; PFAM: formate/nitrite transporter; TIGRFAM: formate/nitrite transporter YP_004100607.1 COGs: COG4117 thiosulfate reductase cytochrome B subunit (membrane anchoring protein); InterPro IPR000572; KEGG: nca:Noca_0316 oxidoreductase, molybdopterin binding; PFAM: oxidoreductase molybdopterin binding; SPTR: oxidoreductase, molybdopterin binding; PFAM: cytochrome b(N-terminal)/b6/petB; oxidoreductase molybdopterin binding domain YP_004100608.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073: IPR000639: IPR005829; KEGG: bbe:BBR47_10850 hypothetical protein; PFAM: alpha/beta hydrolase fold; SPTR: alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold YP_004100609.1 KEGG: nca:Noca_2102 hypothetical protein; SPTR: Conserved hypothetical membrane protein YP_004100610.1 COGs: COG2132 multicopper oxidase; InterPro IPR011707: IPR001287; KEGG: nca:Noca_2101 multicopper oxidase type 3; PFAM: multicopper oxidase type 3; PRIAM: nitrite reductase (NO-forming); SPTR: Copper-containing nitrite reductase; PFAM: Multicopper oxidase; TIGRFAM: nitrite reductase, copper-containing YP_004100611.1 KEGG: kfl:Kfla_1115 major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1 YP_004100612.1 KEGG: cms:CMS_0575 hypothetical protein; SPTR: membrane protein YP_004100613.1 COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR017439: IPR002933: IPR011650: IPR010168; KEGG: kfl:Kfla_3609 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: hippurate hydrolase protein; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase YP_004100614.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: rha:RHA1_ro04308 Fe(3+) uptake regulator; PFAM: ferric-uptake regulator; SPTR: Fe(3+) uptake regulator; PFAM: ferric uptake regulator family YP_004100615.1 COGs: COG0753 catalase; InterPro IPR018028: IPR010582: IPR011614: IPR002226; KEGG: sco:SCO0379 catalase; PFAM: catalase related subgroup; catalase domain protein; PRIAM: catalase; SPTR: catalase; PFAM: catalase; catalase-related immune-responsive YP_004100616.1 InterPro IPR011637; KEGG: sti:Sthe_2149 DoxX family protein; PFAM: DoxX family protein; SPTR: DoxX family protein; PFAM: DoxX YP_004100617.1 InterPro IPR007423; KEGG: art:Arth_0682 hypothetical protein; PFAM: protein of unknown function DUF466; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF466) YP_004100618.1 COGs: COG1966 carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: ach:Achl_0831 carbon starvation protein CstA; PFAM: carbon starvation protein CstA; SPTR: carbon starvation protein CstA; PFAM: carbon starvation protein CstA YP_004100619.1 KEGG: scb:SCAB_58951 integral membrane protein; SPTR: integral membrane protein YP_004100620.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: stp:Strop_0256 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; ABC transporter; X-Pro dipeptidyl-peptidase (S15 family) YP_004100621.1 KEGG: tal:Thal_0571 phosphatidate cytidylyltransferase; SPTR: phosphatidate cytidylyltransferase YP_004100622.1 InterPro IPR002110: IPR020683; KEGG: nda:Ndas_2707 ankyrin; PFAM: ankyrin; SMART: ankyrin; SPTR: ankyrin; PFAM: ankyrin repeat YP_004100623.1 COGs: COG2077 peroxiredoxin; InterPro IPR013740: IPR017936: IPR018219; KEGG: krh:KRH_08020 thiol peroxidase; PFAM: Redoxin domain protein; SPTR: thiol peroxidase; PFAM: Redoxin YP_004100624.1 COGs: COG0554 glycerol kinase; InterPro IPR018484: IPR018485: IPR005999: IPR018483; KEGG: bcv:Bcav_3291 glycerol kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: glycerol kinase; TIGRFAM: glycerol kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004100625.1 COGs: COG4412 conserved hypothetical protein; InterPro IPR012300: IPR008757: IPR017683; KEGG: ade:Adeh_0829 peptidase M6, immune inhibitor A; PFAM: peptidase M6 immune inhibitor A; SPTR: peptidase M6, immune inhibitor A; TIGRFAM: M6 family metalloprotease domain protein; PFAM: Immune inhibitor A peptidase M6; TIGRFAM: M6 family metalloprotease domain YP_004100626.1 COGs: COG0578 glycerol-3-phosphate dehydrogenase; InterPro IPR006076: IPR000447; KEGG: sen:SACE_6515 glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; PRIAM: glycerol-3-phosphate dehydrogenase; SPTR: glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase YP_004100627.1 KEGG: sro:Sros_3608 monooxygenase; SPTR: monooxygenase YP_004100628.1 COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000595: IPR000644: IPR005105: IPR018821; KEGG: tra:Trad_0246 CBS domain and cyclic nucleotide-regulated nucleotidyltransferase; PFAM: protein of unknown function DUF294 nucleotidyltransferase; CBS domain containing protein; cyclic nucleotide-binding; Domain of unknown function DUF294, nucleotidyltransferase substrate-binding; SMART: CBS domain containing protein; cyclic nucleotide-binding; SPTR: CBS domain and cyclic nucleotide-regulated nucleotidyltransferase; PFAM: nucleotidyltransferase substrate binding domain; CBS domain; Cyclic nucleotide-binding domain; nucleotidyltransferase DUF294 YP_004100629.1 COGs: COG0847 DNA polymerase III subunit epsilon and related 3'-5' exonuclease; InterPro IPR013520: IPR006055; KEGG: mgm:Mmc1_1044 exonuclease, RNase T and DNA polymerase III; PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; SPTR: exonuclease RNase T and DNA polymerase III; PFAM: exonuclease YP_004100630.1 COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterPro IPR012319: IPR015886: IPR000214: IPR015887; KEGG: kra:Krad_1488 formamidopyrimidine-DNA glycolase; PFAM: Formamidopyrimidine-DNA glycosylase catalytic domain protein; DNA glycosylase/AP lyase, H2TH DNA-binding; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg) YP_004100631.1 COGs: COG1201 Lhr-like helicase; InterProIPR011545: IPR001650: IPR013701: IPR014021: IPR 014001; KEGG: kra:Krad_1489 DEAD/H associated domain protein; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase; helicase; SMART: DEAD-like helicase; helicase; SPTR: ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase YP_004100632.1 COGs: COG0262 dihydrofolate reductase; InterPro IPR002734; KEGG: rlg:Rleg_4567 bifunctional deaminase-reductase domain protein; PFAM: bifunctional deaminase-reductase domain protein; SPTR: uncharacterized protein; PFAM: RibD C-terminal domain YP_004100633.1 COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644; KEGG: sen:SACE_3488 CBS domain-containing protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: CBS domain protein; PFAM: CBS domain YP_004100634.1 COGs: COG1289 membrane protein; KEGG: dra:DR_2205 hypothetical protein; SPTR: uncharacterized protein YP_004100635.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR000330: IPR001650: IPR014021: IPR014001; KEGG: mtf:TBFG_12135 helicase HelZ; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase; SPTR: Helicase helZ; manually curated; PFAM: SNF2 Helicase protein; Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004100636.1 COGs: COG4279 conserved hypothetical protein; InterPro IPR007527; KEGG: mtb:TBMG_01880 hypothetical protein; SPTR: uncharacterized protein; PFAM: SWIM zinc finger YP_004100637.1 COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR003953: IPR003042; KEGG: rop:ROP_15470 oxidoreductase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Aromatic-ring hydroxylase; PFAM: FAD binding domain YP_004100638.1 InterPro IPR017517; KEGG: aau:AAur_0329 mycothiol-dependent maleylpyruvate isomerase; SPTR: uncharacterized protein sdgF; PFAM: MDMPI C-terminal domain; Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: uncharacterized Actinobacterial protein TIGR03083 YP_004100639.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: svi:Svir_20690 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: Fumarylacetoacetate hydrolase domain-containing protein 2A; PFAM: Fumarylacetoacetate (FAA) hydrolase family YP_004100640.1 COGs: COG3435 Gentisate 1 2-dioxygenase; InterPro IPR013096; KEGG: ctt:CtCNB1_2778 gentisate 1,2-dioxygenase; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Gentisate 1,2-dioxygenase; PFAM: Cupin domain YP_004100641.1 COGs: COG1414 transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: aau:AAur_0332 IclR family transcriptional regulator; PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004100642.1 COGs: COG4581 Superfamily II RNA helicase; InterPro IPR011545: IPR001650: IPR014021: IPR014001; KEGG: saq:Sare_1716 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase; SMART: DEAD-like helicase; helicase; SPTR: DEAD/DEAH box helicase domain-containing protein; manually curated; PFAM: Domain of unknown function (DUF3516); Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004100643.1 COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: ske:Sked_33800 PadR family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: uncharacterized protein; PFAM: transcriptional regulator PadR-like family YP_004100644.1 InterPro IPR006162; KEGG: bbt:BBta_6711 sugar ABC transporter membrane protein; SPTR: uncharacterized protein YP_004100645.1 InterPro IPR009597; KEGG: ske:Sked_35130 protein of unknown function (DUF1206); PFAM: protein of unknown function DUF1206; SPTR: uncharacterized protein; PFAM: Domain of Unknown Function (DUF1206) YP_004100646.1 InterPro IPR000326; KEGG: cfl:Cfla_2162 phosphoesterase PA-phosphatase related protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: phosphoesterase PA-phosphatase related protein; PFAM: PAP2 superfamily YP_004100647.1 COGs: COG0671 membrane-associated phospholipid phosphatase; InterPro IPR000326; KEGG: cfl:Cfla_2161 phosphoesterase PA-phosphatase related protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: Conserved hypothetical, predicted membrane protein (TMS6); PFAM: PAP2 superfamily YP_004100648.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: xce:Xcel_3229 diacylglycerol kinase; PFAM: diacylglycerol kinase catalytic region; SPTR: diacylglycerol kinase; PFAM: diacylglycerol kinase catalytic domain YP_004100649.1 KEGG: kfl:Kfla_0873 hypothetical protein; SPTR: uncharacterized protein YP_004100650.1 InterPro IPR018392: IPR002482; KEGG: pjd:Pjdr2_5940 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: CLV1 receptor kinase; PFAM: LysM domain YP_004100651.1 KEGG: tpr:Tpau_2285 hypothetical protein; SPTR: Major facilitator superfamily permease YP_004100652.1 KEGG: hne:HNE_2981 hypothetical protein; SPTR: membrane protein YP_004100653.1 InterPro IPR011701; KEGG: sgr:SGR_619 major facilitator superfamily permease; PFAM: major facilitator superfamily MFS_1; SPTR: Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily YP_004100654.1 COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterProIPR003439: IPR013563: IPR010066: IPR017871: IPR 003593; KEGG: stp:Strop_3819 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004100655.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR003439: IPR013563: IPR010066: IPR017871: IPR 003593; KEGG: saq:Sare_4210 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain YP_004100656.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: stp:Strop_3821 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004100657.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: saq:Sare_4212 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component YP_004100658.1 COGs: COG4166 ABC-type oligopeptide transporter periplasmic component; InterPro IPR000914; KEGG: stp:Strop_2462 4-phytase; PFAM: extracellular solute-binding protein family 5; SPTR: 4-phytase; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004100659.1 COGs: COG0648 endonuclease IV; InterPro IPR012307: IPR001719: IPR018246; KEGG: nca:Noca_4666 endonuclease IV; PFAM: Xylose isomerase domain-containing protein TIM barrel; SMART: AP endonuclease family 2; SPTR: endonuclease IV; manually curated; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1) YP_004100660.1 COGs: COG0842 ABC-type multidrug transporter permease; InterPro IPR013525: IPR000412; KEGG: mjl:Mjls_4638 ABC-2 type transporter; PFAM: ABC transporter; SPTR: ABC transporter; manually curated; PFAM: ABC transporter YP_004100661.1 COGs: COG3573 oxidoreductase; InterPro IPR014614: IPR003953; KEGG: nca:Noca_1140 FAD-binding dehydrogenase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain YP_004100662.1 InterPro IPR003615; KEGG: rop:ROP_20630 hypothetical protein; SMART: HNH nuclease; SPTR: uncharacterized protein YP_004100663.1 COGs: COG3345 alpha-galactosidase; InterPro IPR002252: IPR000111; KEGG: kfl:Kfla_1749 glycoside hydrolase clan GH-D; PFAM: glycoside hydrolase clan GH-D; PRIAM: alpha-galactosidase; SPTR: glycoside hydrolase clan GH-D; PFAM: Melibiase YP_004100664.1 COGs: COG0389 nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR001126: IPR017963; KEGG: art:Arth_2021 DNA polymerase IV; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: DNA-directed DNA polymerase; PFAM: impB/mucB/samB family C-terminal; impB/mucB/samB family YP_004100665.1 KEGG: cwo:Cwoe_2689 transporter permease; SPTR: transporter permease YP_004100666.1 COGs: COG3651 conserved hypothetical protein; InterPro IPR018714; KEGG: mjl:Mjls_5338 hypothetical protein; PFAM: protein of unknown function DUF2237; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2237) YP_004100667.1 KEGG: rci:RCIX660 hypothetical protein; SPTR: Excretory/secretory mucin MUC-5 YP_004100668.1 InterPro IPR010895; KEGG: pzu:PHZ_c0812 hypothetical protein; SMART: CHRD domain containing protein; SPTR: uncharacterized protein; PFAM: CHRD domain YP_004100669.1 KEGG: cwo:Cwoe_0906 endonuclease/exonuclease/phosphatase; SPTR: endonuclease/exonuclease/phosphatase YP_004100670.1 COGs: COG2357 conserved hypothetical protein; InterPro IPR007685; KEGG: nca:Noca_4620 RelA/SpoT domain-containing protein; PFAM: RelA/SpoT domain protein; SPTR: RelA/SpoT domain protein; PFAM: Region found in RelA / SpoT proteins YP_004100671.1 COGs: COG1280 threonine efflux protein; InterPro IPR001123; KEGG: nca:Noca_4624 lysine exporter protein LysE/YggA; PFAM: lysine exporter protein (LYSE/YGGA); SPTR: lysine exporter (LYSE/YGGA); PFAM: LysE type translocator YP_004100672.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: tcu:Tcur_0128 chromosome partitioning ATPase; SPTR: ATPase involved in chromosome partitioning-like protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004100673.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR016166; KEGG: saq:Sare_0966 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase; SPTR: FAD linked oxidase; manually curated; PFAM: FAD binding domain YP_004100674.1 COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR003333; KEGG: nca:Noca_1917 cyclopropane-fatty-acyl-phospholipid synthase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; SPTR: Cyclopropane-fatty-acyl-phospholipid synthase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase YP_004100675.1 KEGG: cai:Caci_7393 hypothetical protein; SPTR: uncharacterized protein YP_004100676.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: cef:CE0057 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: NreA protein; PFAM: Uncharacterised BCR, COG1937 YP_004100677.1 InterPro IPR013217; KEGG: tfu:Tfu_0055 hypothetical protein; PFAM: methyltransferase type 12; SPTR: uncharacterized protein; PFAM: Tellurite resistance protein TehB YP_004100678.1 KEGG: nml:Namu_5352 flavodoxin/nitric oxide synthase; SPTR: uncharacterized protein YP_004100679.1 COGs: COG2409 drug exporter of the RND superfamily; InterPro IPR000731; KEGG: nca:Noca_2172 MmpL domain-containing protein; SPTR: MMPL domain protein; manually curated; PFAM: MMPL family YP_004100680.1 InterPro IPR001647; KEGG: nca:Noca_2173 regulatory protein, TetR; PFAM: regulatory protein TetR; SPTR: Regulatory protein, TetR; PFAM: Bacterial regulatory proteins, tetR family YP_004100681.1 COGs: COG1573 uracil-DNA glycosylase; InterPro IPR005122; KEGG: bcv:Bcav_1028 uracil-DNA glycosylase; PFAM: uracil-DNA glycosylase; SPTR: uncharacterized protein; PFAM: uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4 YP_004100682.1 COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: phe:Phep_0285 O-methyltransferase; PFAM: O-methyltransferase family 3; SPTR: O-methyltransferase; PFAM: O-methyltransferase YP_004100683.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR007630: IPR014284; KEGG: art:Arth_3789 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004100684.1 KEGG: art:Arth_4387 hypothetical protein; SPTR: uncharacterized protein YP_004100685.1 InterPro IPR020311; KEGG: kfl:Kfla_3461 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2630) YP_004100686.1 COGs: COG0412 Dienelactone hydrolase; KEGG: art:Arth_0598 dienelactone hydrolase; SPTR: Dienelactone hydrolase; PFAM: Dienelactone hydrolase family YP_004100687.1 COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: rop:ROP_65980 hypothetical protein; PFAM: patatin; SPTR: uncharacterized protein; PFAM: patatin-like phospholipase YP_004100688.1 KEGG: nml:Namu_0371 hypothetical protein; SPTR: uncharacterized protein; PFAM: Luciferase-like monooxygenase YP_004100689.1 KEGG: nca:Noca_0914 hypothetical protein; SPTR: uncharacterized protein YP_004100690.1 COGs: COG4405 conserved hypothetical protein; InterPro IPR009326: IPR007374; KEGG: ske:Sked_10710 conserved hypothetical protein TIGR00026; PFAM: protein of unknown function DUF437; SPTR: uncharacterized protein; PFAM: ASCH domain YP_004100691.1 KEGG: gob:Gobs_0702 hypothetical protein; SPTR: uncharacterized protein YP_004100693.1 COGs: COG0657 esterase/lipase; KEGG: brm:Bmur_0056 esterase; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold YP_004100694.1 InterPro IPR004360; KEGG: kfl:Kfla_4696 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase/bleomycin resistance protein/dioxygenase; manually curated; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004100695.1 InterPro IPR000182; KEGG: saq:Sare_2086 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004100696.1 COGs: COG4101 mannose-6-phosphate isomerase; InterPro IPR013096; KEGG: nca:Noca_2772 cupin 2 domain-containing protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Cupin 2, conserved barrel domain protein; manually curated; PFAM: Cupin domain YP_004100697.1 KEGG: rha:RHA1_ro07227 hypothetical protein; SPTR: uncharacterized protein YP_004100698.1 COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154; KEGG: nar:Saro_2892 NADH oxidoreductase; PFAM: alcohol dehydrogenase GroES; SPTR: NADH oxidoreductase YP_004100699.1 InterPro IPR003477; KEGG: fal:FRAAL5929 hypothetical protein; PFAM: PemK family protein; SPTR: uncharacterized protein; PFAM: PemK-like protein YP_004100700.1 KEGG: bpd:BURPS668_A2787 F0F1 ATP synthase subunit alpha; SPTR: xanthine dehydrogenase accessory factor YP_004100701.1 KEGG: rlt:Rleg2_5666 drug resistance transporter EmrB/QacA subfamily; SPTR: uncharacterized protein YP_004100702.1 COGs: COG3547 transposase and inactivated derivatives; InterPro IPR003346; KEGG: mgi:Mflv_0689 transposase IS116/IS110/IS902 family protein; PFAM: transposase IS116/IS110/IS902 family protein; SPTR: IS110 family transposase; PFAM: transposase IS116/IS110/IS902 family; transposase YP_004100703.1 InterPro IPR013096; KEGG: rle:RL3059 hypothetical protein; PFAM: cupin; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004100704.1 COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR007712; KEGG: rop:ROP_29420 hypothetical protein; PFAM: plasmid stabilization system; SPTR: uncharacterized protein; PFAM: Plasmid stabilisation system protein YP_004100705.1 InterPro IPR006442; KEGG: cwo:Cwoe_0848 prevent-host-death family protein; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004100706.1 KEGG: nca:Noca_4727 hypothetical protein; SPTR: uncharacterized protein YP_004100707.1 COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: gbr:Gbro_4732 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004100708.1 InterPro IPR002514; KEGG: rop:ROP_pROB01-03840 transposase; PFAM: transposase IS3/IS911 family protein; SPTR: transposase YP_004100709.1 KEGG: nca:Noca_4727 hypothetical protein; SPTR: uncharacterized protein YP_004100710.1 KEGG: nca:Noca_4726 hypothetical protein; SPTR: uncharacterized protein YP_004100711.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nca:Noca_4725 phage integrase; PFAM: integrase; SPTR: Phage integrase; PFAM: Phage integrase family YP_004100712.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086: IPR020476: IPR020084; KEGG: nca:Noca_3209 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; manually curated; PFAM: NUDIX domain YP_004100713.1 COGs: COG4923 conserved hypothetical protein; KEGG: ske:Sked_27390 hypothetical protein; SPTR: Uncharacterized conserved protein; PFAM: protein of unknown function (DUF429) YP_004100714.1 KEGG: ach:Achl_1702 hypothetical protein; SPTR: uncharacterized protein YP_004100715.1 InterPro IPR000182; KEGG: cai:Caci_7727 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004100716.1 KEGG: kfl:Kfla_3753 hypothetical protein; SPTR: deoxyguanosinetriphosphate triphosphohydrolase YP_004100717.1 KEGG: rpd:RPD_3661 hypothetical protein; SPTR: uncharacterized protein YP_004100718.1 COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: ach:Achl_3248 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; manually curated; PFAM: acetyltransferase (GNAT) family YP_004100719.1 COGs: COG3464 transposase and inactivated derivatives; InterPro IPR002560; KEGG: mlu:Mlut_14300 transposase; PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; SPTR: transposase; PFAM: transposase YP_004100720.1 KEGG: cef:CE1256 hypothetical protein; SPTR: uncharacterized protein YP_004100721.1 KEGG: cef:CE1255 hypothetical protein; SPTR: uncharacterized protein; PFAM: Ribbon-helix-helix protein, copG family YP_004100722.1 COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR011876: IPR000086; KEGG: sen:SACE_5210 isopentenyl-diphosphate delta-isomerase; PFAM: NUDIX hydrolase; PRIAM: Isopentenyl-diphosphate delta-isomerase; SPTR: Isopentenyl-diphosphate delta-isomerase; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1 YP_004100723.1 COGs: COG0644 dehydrogenase (flavoprotein); InterPro IPR006076: IPR003042; KEGG: mpa:MAP2644 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase; PFAM: FAD binding domain YP_004100724.1 COGs: COG1755 conserved hypothetical protein; InterPro IPR007269; KEGG: kfl:Kfla_2548 isoprenylcysteine carboxyl methyltransferase; PFAM: isoprenylcysteine carboxyl methyltransferase; SPTR: isoprenylcysteine carboxyl methyltransferase; PFAM: isoprenylcysteine carboxyl methyltransferase (ICMT) family YP_004100725.1 COGs: COG3424 naringenin-chalcone synthase; InterPro IPR011141: IPR001099: IPR012328; KEGG: kse:Ksed_00500 predicted naringenin-chalcone synthase; PFAM: chalcone and stilbene synthase domain protein; SPTR: Chalcone and stilbene synthases domain-containing protein; PFAM: FAE1/type III polyketide synthase-like protein; Chalcone and stilbene synthases, C-terminal domain YP_004100726.1 InterPro IPR000537; KEGG: nml:Namu_5114 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: integral membrane protein; PFAM: UbiA prenyltransferase family YP_004100727.1 COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755; KEGG: kse:Ksed_15620 DNA polymerase LigD, polymerase domain; PFAM: DNA primase small subunit; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain YP_004100728.1 COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR012309; KEGG: nml:Namu_0826 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: DNA ligase; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region YP_004100729.1 COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760: IPR020583; KEGG: pfr:PFREUD_08740 inositol-phosphate phosphatase; PFAM: inositol monophosphatase; SPTR: inositol monophosphatase family protein; PFAM: inositol monophosphatase family YP_004100730.1 InterPro IPR001647: IPR004111: IPR003012; KEGG: tfu:Tfu_1997 TetR family transcriptional regulator; PFAM: regulatory protein TetR; Tetracyclin repressor domain-containing protein; SPTR: transcriptional regulator, TetR family; PFAM: Tetracyclin repressor, C-terminal all-alpha domain; Bacterial regulatory proteins, tetR family YP_004100731.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: nca:Noca_4292 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004100732.1 KEGG: nfa:nfa6780 hypothetical protein; SPTR: uncharacterized protein YP_004100733.1 COGs: COG0515 serine/threonine protein kinase; InterProIPR017442: IPR000719: IPR008271: IPR020635: IPR 002290; KEGG: nda:Ndas_5247 serine/threonine protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: transmembrane serine/threonine-protein kinase a pkna (proteinkinase a) (Stpk a); PFAM: protein kinase domain YP_004100734.1 COGs: COG2508 Regulator of polyketide synthase expression; KEGG: sen:SACE_5329 transcriptional regulator; SPTR: transcriptional regulator YP_004100735.1 COGs: COG2403 GTPase; InterPro IPR003495; KEGG: ton:TON_1432 hypothetical protein; PFAM: cobalamin synthesis protein P47K; SPTR: uncharacterized protein; PFAM: CobW/HypB/UreG, nucleotide-binding domain YP_004100736.1 COGs: COG4992 ornithine/acetylornithine aminotransferase; InterPro IPR005814: IPR010164: IPR005829; KEGG: gob:Gobs_2808 ornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: RocD1; TIGRFAM: ornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: ornithine aminotransferase YP_004100737.1 KEGG: gob:Gobs_2926 hypothetical protein; SPTR: uncharacterized protein YP_004100738.1 KEGG: xce:Xcel_1911 protein of unknown function DUF88; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF88 YP_004100739.1 COGs: COG0474 Cation transport ATPase; InterProIPR004014: IPR008250: IPR005834: IPR006068: IPR 001757: IPR000695: IPR018303; KEGG: bcv:Bcav_4202 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; haloacid dehalogenase; SPTR: ATPase, P-type (transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase P YP_004100740.1 KEGG: xce:Xcel_2365 hypothetical protein; SPTR: uncharacterized protein YP_004100741.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: afo:Afer_0162 rhodanese domain protein; PFAM: rhodanese; SMART: rhodanese; SPTR: rhodanese; PFAM: Rhodanese-like domain YP_004100742.1 KEGG: nca:Noca_3724 phosphodiesterase; SPTR: phosphodiesterase YP_004100743.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: nca:Noca_0141 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: NreA protein; PFAM: Uncharacterised BCR, COG1937 YP_004100744.1 COGs: COG0599 gamma-carboxymuconolactone decarboxylase subunit; InterPro IPR003779: IPR004675; KEGG: nca:Noca_3748 alkylhydroperoxidase; PFAM: carboxymuconolactone decarboxylase; SPTR: Alkylhydroperoxidase like protein, AhpD family; TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain YP_004100745.1 InterPro IPR018929; KEGG: pfr:PFREUD_07460 hypothetical protein; PFAM: protein of unknown function DUF2510; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2510) YP_004100746.1 KEGG: saq:Sare_1132 hypothetical protein; SPTR: uncharacterized protein YP_004100747.1 KEGG: sgr:SGR_4345 hypothetical protein; SPTR: uncharacterized protein YP_004100748.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254: IPR001940; KEGG: cfl:Cfla_1619 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SPTR: peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin YP_004100749.1 KEGG: cfl:Cfla_1620 hypothetical protein; SPTR: uncharacterized protein; PFAM: fimbrial assembly protein (PilN) YP_004100750.1 InterPro IPR006166; KEGG: nca:Noca_3806 ERCC4 domain-containing protein; PFAM: ERCC4 domain protein; SPTR: ERCC4 domain protein; PFAM: Lsr2 YP_004100751.1 KEGG: svi:Svir_10360 hypothetical protein; SPTR: uncharacterized protein YP_004100752.1 KEGG: kra:Krad_0338 hypothetical protein; SPTR: uncharacterized protein YP_004100753.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: gob:Gobs_4160 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: acyl-CoA synthetase, long-chain fatty acid:CoA ligase; PFAM: AMP-binding enzyme YP_004100754.1 KEGG: aau:AAur_0122 hypothetical protein; SPTR: uncharacterized protein YP_004100755.1 KEGG: art:Arth_0347 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1469) YP_004100756.1 KEGG: pfr:PFREUD_00910 hypothetical membrane protein; SPTR: Hypothetical membrane protein; PFAM: protein of unknown function (DUF3618) YP_004100757.1 COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133: IPR000262: IPR008259; KEGG: sen:SACE_6523 lactate 2-monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase YP_004100758.1 COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: kfl:Kfla_1299 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004100759.1 KEGG: kfl:Kfla_5902 hypothetical protein; SPTR: uncharacterized protein YP_004100760.1 InterPro IPR003482: IPR000637; KEGG: kra:Krad_1181 transcription factor WhiB; PFAM: transcription factor WhiB; SPTR: transcription factor WhiB; PFAM: transcription factor WhiB YP_004100761.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR012951: IPR016166; KEGG: cai:Caci_4344 FAD linked oxidase domain protein; PFAM: FAD linked oxidase; Berberine/berberine domain protein; SPTR: FAD linked oxidase domain containing protein; PFAM: FAD binding domain; Berberine and berberine like YP_004100762.1 InterPro IPR011701: IPR005829; KEGG: saq:Sare_2495 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004100763.1 KEGG: mbt:JTY_1033 hypothetical protein; SPTR: uncharacterized protein YP_004100764.1 COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: nca:Noca_2673 alcohol dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; SPTR: alcohol dehydrogenase, zinc-binding domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004100765.1 InterPro IPR002514; KEGG: bcv:Bcav_0946 transposase IS3/IS911 family protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase IS3/IS911 family protein; PFAM: transposase YP_004100766.1 KEGG: app:CAP2UW1_4212 competence protein ComEA helix-hairpin-helix repeat protein; SPTR: inositol-5-monophosphate dehydrogenase YP_004100767.1 COGs: COG3942 Surface antigen; InterPro IPR007921; KEGG: ooe:OEOE_1430 cell wall hydrolase; PFAM: CHAP domain containing protein; SPTR: cell wall-associated hydrolase with LysM domains; PFAM: CHAP domain YP_004100768.1 COGs: COG1506 dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR003140; KEGG: kfl:Kfla_4635 peptidase S9 prolyl oligopeptidase active site domain protein; PFAM: phospholipase/carboxylesterase; SPTR: peptidase S9 prolyl oligopeptidase active site domain protein; PFAM: prolyl oligopeptidase family YP_004100769.1 KEGG: sna:Snas_3241 hypothetical protein; SPTR: uncharacterized protein YP_004100770.1 InterPro IPR007527; KEGG: aau:AAur_2031 SWIM zinc finger domain-containing protein; SPTR: SWIM zinc finger domain protein; PFAM: SWIM zinc finger YP_004100771.1 InterPro IPR008912; KEGG: aau:AAur_2027 VWA domain CoxE-like family protein; PFAM: VWA containing CoxE family protein; SPTR: VWA domain containing CoxE-like protein family; PFAM: VWA domain containing CoxE-like protein YP_004100772.1 InterPro IPR000182; KEGG: sma:SAV_5596 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family YP_004100773.1 COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021: IPR002071; KEGG: kse:Ksed_15970 micrococcal nuclease-like nuclease; PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Micrococcal nuclease-like nuclease; PFAM: Staphylococcal nuclease homologue YP_004100774.1 COGs: COG1171 threonine dehydratase; InterPro IPR001926: IPR001721: IPR005787: IPR000634; KEGG: eta:ETA_01880 threonine dehydratase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; threonine dehydratase domain-containing protein; SPTR: threonine dehydratase; TIGRFAM: threonine dehydratase, biosynthetic; PFAM: C-terminal regulatory domain of threonine dehydratase; pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form YP_004100775.1 InterPro IPR008757; KEGG: kra:Krad_3710 hypothetical protein; PFAM: peptidase M6 immune inhibitor A; SPTR: uncharacterized protein; PFAM: Immune inhibitor A peptidase M6 YP_004100776.1 KEGG: bcv:Bcav_1842 hypothetical protein; SPTR: uncharacterized protein YP_004100777.1 COGs: COG2716 glycine cleavage system regulatory protein; InterPro IPR016867: IPR002912; KEGG: tkm:TK90_2229 amino acid-binding ACT domain protein; PFAM: amino acid-binding ACT domain protein; SPTR: uncharacterized protein; PFAM: ACT domain YP_004100778.1 COGs: COG3608 deacylase; InterPro IPR007036: IPR000834; KEGG: mlu:Mlut_23200 predicted deacylase; PFAM: succinylglutamate desuccinylase/aspartoacylase; SPTR: succinylglutamate desuccinylase/aspartoacylase; PFAM: succinylglutamate desuccinylase / aspartoacylase family YP_004100779.1 COGs: COG4067 conserved hypothetical protein; InterPro IPR008503; KEGG: lxx:Lxx24490 hypothetical protein; PFAM: protein of unknown function DUF785; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF785) YP_004100780.1 COGs: COG0189 glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR013651: IPR006037: IPR011761: IPR004666; KEGG: mlu:Mlut_23180 30S ribosomal protein S6P modification protein; PFAM: RimK domain protein ATP-grasp; TrkA-C domain protein; SPTR: ribosomal protein S6 modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK-like ATP-grasp domain; TrkA-C domain; TIGRFAM: alpha-L-glutamate ligases, RimK family YP_004100781.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: nml:Namu_2578 beta-lactamase domain protein; PFAM: rhodanese; SMART: rhodanese; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily; Rhodanese-like domain YP_004100783.1 COGs: COG0001 glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: fal:FRAAL6024 glutamate-1-semialdehyde aminotransferase (aminomutase), PLP-dependent; PFAM: aminotransferase class-III; SPTR: glutamate-1-semialdehyde aminotransferase (Aminomutase), PLP-dependent; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase YP_004100784.1 COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: tbi:Tbis_2483 luciferase-like monooxygenase; PFAM: Luciferase-like, subgroup; SPTR: Luciferase-like monooxygenase; PFAM: Luciferase-like monooxygenase YP_004100785.1 KEGG: sna:Snas_0537 kelch repeat-containing protein; SPTR: Kelch repeat-containing protein YP_004100786.1 InterPro IPR000620; KEGG: sen:SACE_0263 amino acid ABC transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004100787.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sen:SACE_0264 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Probable LysR family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004100788.1 InterPro IPR012506; KEGG: xce:Xcel_1936 YhhN family protein; PFAM: YhhN family protein; SPTR: uncharacterized protein; PFAM: YhhN-like protein YP_004100789.1 KEGG: nth:Nther_1572 hypothetical protein; SPTR: uncharacterized protein YP_004100790.1 COGs: COG1760 L-serine deaminase; InterPro IPR005131: IPR005130: IPR004644; KEGG: kse:Ksed_16840 L-serine ammonia-lyase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; PRIAM: L-serine ammonia-lyase; SPTR: L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form YP_004100791.1 COGs: COG0320 Lipoate synthase; InterPro IPR003698: IPR007197: IPR006638; KEGG: ace:Acel_0926 lipoyl synthase; PFAM: radical SAM domain protein; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoyl synthase; TIGRFAM: lipoic acid synthetase; PFAM: radical SAM superfamily; TIGRFAM: lipoate synthase YP_004100792.1 COGs: COG0112 glycine/serine hydroxymethyltransferase; InterPro IPR001085: IPR019798; KEGG: sco:SCO5470 serine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: glycine hydroxymethyltransferase; SPTR: serine hydroxymethyltransferase; PFAM: serine hydroxymethyltransferase YP_004100793.1 COGs: COG0509 glycine cleavage system protein H (lipoate-binding); InterPro IPR002930: IPR017453: IPR003016; KEGG: svi:Svir_13340 glycine cleavage system protein H; PFAM: glycine cleavage H-protein; SPTR: glycine cleavage system protein H; TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein YP_004100794.1 COGs: COG0404 glycine cleavage system protein T (aminomethyltransferase); InterPro IPR006223: IPR006222: IPR013977; KEGG: sma:SAV_2773 glycine cleavage system aminomethyltransferase T; PFAM: glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; SPTR: Aminomethyltransferase; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: glycine cleavage system T protein YP_004100795.1 COGs: COG1003 glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR020580: IPR003437; KEGG: nca:Noca_2709 glycine dehydrogenase; PFAM: glycine cleavage system P-protein-like; SPTR: glycine dehydrogenase [decarboxylating]; TIGRFAM: glycine dehydrogenase; PFAM: glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating) YP_004100796.1 COGs: COG1113 gamma-aminobutyrate permease and related permease; InterPro IPR002293: IPR004841: IPR004840; KEGG: rha:RHA1_ro02269 amino acid APC transporter; PFAM: amino acid permease-associated region; SPTR: D-serine/D-alanine/glycine transporter APC family protein; PFAM: Amino acid permease; TC 2.A.3.1.7 YP_004100797.1 COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: sro:Sros_8858 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter YP_004100798.1 InterPro IPR013525: IPR000412; KEGG: kra:Krad_2016 ABC-2 type transporter; PFAM: ABC transporter; SPTR: ABC transporter; PFAM: ABC transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_004100799.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: kra:Krad_2015 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: MerR family transcriptional regulator; PFAM: MerR family regulatory protein YP_004100800.1 KEGG: bcv:Bcav_3050 twin-arginine translocation pathway signal; SPTR: Twin-arginine translocation pathway signal; PFAM: protein of unknown function (DUF664) YP_004100801.1 COGs: COG2334 homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: bmr:BMI_II1170 hypothetical protein; PFAM: aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase; PFAM: phosphotransferase enzyme family YP_004100802.1 COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: eta:ETA_17300 amino acid aminotransferase; PFAM: aminotransferase class I and II; SPTR: Amino acid aminotransferase; PFAM: Aminotransferase class I and II YP_004100803.1 COGs: COG0305 Replicative DNA helicase; InterProIPR007693: IPR007694: IPR007692: IPR006141: IPR 003587; KEGG: mlb:MLBr_02680 replicative DNA helicase; PFAM: DnaB domain protein helicase; SMART: Hedgehog/intein hint domain protein; SPTR: Replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; intein C-terminal splicing region YP_004100804.1 COGs: COG5552 conserved hypothetical protein; InterPro IPR018735; KEGG: ach:Achl_3874 hypothetical protein; PFAM: protein of unknown function DUF2277; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2277) YP_004100805.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: rha:RHA1_ro00901 phosphoesterase; PFAM: metallophosphoesterase; SPTR: Possible phosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004100806.1 InterPro IPR018201; KEGG: kfl:Kfla_0729 hypothetical protein; SPTR: uncharacterized protein; PFAM: Pregnancy-associated plasma protein-A YP_004100807.1 InterPro IPR014825; KEGG: amd:AMED_6049 DNA alkylation repair enzyme; PFAM: DNA alkylation repair enzyme; SPTR: uncharacterized protein; PFAM: DNA alkylation repair enzyme YP_004100808.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: pac:PPA2259 hypothetical protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Conserved membrane protein, MatE domain; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004100809.1 COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: ach:Achl_0399 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: solute binding lipoprotein; PFAM: Bacterial extracellular solute-binding protein YP_004100810.1 COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: ach:Achl_0400 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Multiple sugar transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component YP_004100811.1 COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: ach:Achl_0401 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: sugar transport integral membrane protein; PFAM: Binding-protein-dependent transporter inner membrane component YP_004100812.1 COGs: COG2723 beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360: IPR017736; KEGG: jde:Jden_1879 beta-galactosidase; PFAM: glycoside hydrolase family 1; PRIAM: beta-glucosidase; SPTR: cellobiose hydrolase; TIGRFAM: beta-galactosidase; PFAM: glycosyl hydrolase family 1; TIGRFAM: beta-galactosidase YP_004100813.1 COGs: COG1609 transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: aau:AAur_0084 LacI family transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Regulatory protein, LacI; PFAM: Bacterial regulatory proteins, lacI family; family YP_004100814.1 COGs: COG0359 ribosomal protein L9; InterPro IPR020070: IPR020069: IPR020594; KEGG: scb:SCAB_46131 50S ribosomal protein L9; PFAM: ribosomal protein L9-like; SPTR: 50S ribosomal protein L9; TIGRFAM: ribosomal protein L9; PFAM: ribosomal protein L9, N-terminal domain; ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_004100815.1 COGs: COG0238 ribosomal protein S18; InterPro IPR001648: IPR018275; KEGG: cfl:Cfla_3698 ribosomal protein S18; PFAM: ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: ribosomal protein S18; PFAM: ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_004100816.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424: IPR011344; KEGG: kra:Krad_4338 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004100817.1 COGs: COG0360 ribosomal protein S6; InterPro IPR020814: IPR000529: IPR020815; KEGG: aau:AAur_4165 30S ribosomal protein S6; PFAM: ribosomal protein S6, bacterial-like; SPTR: 30S ribosomal protein S6; TIGRFAM: ribosomal protein S6; PFAM: ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_004100818.1 COGs: COG5650 integral membrane protein; KEGG: kra:Krad_4340 integral membrane protein; SPTR: transmembrane protein; PFAM: protein of unknown function (DUF2029) YP_004100819.1 COGs: COG0744 membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kra:Krad_4341 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: secreted penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; transglycosylase YP_004100820.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014325: IPR014284; KEGG: kfl:Kfla_6274 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_004100821.1 KEGG: kfl:Kfla_6275 hypothetical protein; SPTR: uncharacterized protein YP_004100822.1 COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: ace:Acel_2137 PadR family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: PadR family transcriptional regulator; PFAM: transcriptional regulator PadR-like family YP_004100823.1 COGs: COG1260 myo-inositol-1-phosphate synthase; InterPro IPR002587: IPR013021: IPR017815; KEGG: nca:Noca_4678 myo-inositol-1-phosphate synthase; PFAM: myo-inositol-1-phosphate synthase; myo-inositol-1-phosphate synthase GAPDH domain protein; SPTR: myo-inositol-1-phosphate synthase; TIGRFAM: inositol 1-phosphate synthase; PFAM: myo-inositol-1-phosphate synthase; TIGRFAM: inositol 1-phosphate synthase, Actinobacterial type YP_004100824.1 InterPro IPR000209; KEGG: kfl:Kfla_4187 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: protease; PFAM: Subtilase family YP_004100825.1 KEGG: kfl:Kfla_4186 tetratricopeptide TPR_4; SPTR: hypothetical protein YP_004100826.1 KEGG: cai:Caci_5300 hypothetical protein; SPTR: uncharacterized protein YP_004100827.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR014284; KEGG: amd:AMED_1362 RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004100828.1 KEGG: mab:MAB_3781 hypothetical protein; SPTR: uncharacterized protein YP_004100829.1 COGs: COG0631 serine/threonine protein phosphatase; InterPro IPR010822: IPR001932; KEGG: ami:Amir_1685 protein serine/threonine phosphatase; PFAM: stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: protein phosphatase; PFAM: protein phosphatase 2C YP_004100830.1 KEGG: msm:MSMEG_3229 hypothetical protein; SPTR: uncharacterized protein YP_004100831.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterProIPR002646: IPR006674: IPR014065: IPR006675: IPR 003607; KEGG: kse:Ksed_26890 tRNA adenylyltransferase; PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: RNA nucleotidyltransferase; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: HD domain; poly A polymerase head domain; TIGRFAM: tRNA adenylyltransferase; uncharacterized domain HDIG YP_004100832.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086: IPR020476: IPR020084; KEGG: kse:Ksed_26900 ADP-ribose pyrophosphatase; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004100833.1 KEGG: ske:Sked_37910 hypothetical protein; SPTR: uncharacterized protein YP_004100834.1 KEGG: cfl:Cfla_3716 hypothetical protein; SPTR: uncharacterized protein YP_004100835.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: svi:Svir_39650 RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004100836.1 KEGG: tfu:Tfu_3107 hypothetical protein; SPTR: RNA polymerase sigma-70 factor YP_004100837.1 COGs: COG0492 thioredoxin reductase; InterPro IPR013027: IPR000103: IPR005982: IPR008255; KEGG: kse:Ksed_26940 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_004100838.1 COGs: COG3118 thioredoxin domain-containing protein; InterProIPR013766: IPR017936: IPR006662: IPR005746: IPR 017937; KEGG: tbi:Tbis_3579 thioredoxin; PFAM: thioredoxin domain-containing protein; SPTR: thioredoxin; TIGRFAM: thioredoxin; PFAM: thioredoxin; TIGRFAM: thioredoxin YP_004100839.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002477: IPR002508; KEGG: kfl:Kfla_7065 cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin; peptidoglycan-binding protein; SMART: cell wall hydrolase/autolysin; SPTR: cell wall hydrolase/autolysin; PFAM: peptidoglycan binding domain; N-acetylmuramoyl-L-alanine amidase YP_004100840.1 InterPro IPR000182; KEGG: scb:SCAB_45911 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family YP_004100841.1 KEGG: yli:YALI0A00374g YALI0A00374p; SPTR: Predicted protein YP_004100842.1 COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: rop:ROP_36970 3',5'-cyclic-nucleotide phosphodiesterase; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004100843.1 InterPro IPR004378; KEGG: bcv:Bcav_0930 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF385); TIGRFAM: deazaflavin-dependent nitroreductase family protein YP_004100844.1 COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterPro IPR012319: IPR015886: IPR000214: IPR015887; KEGG: mpa:MAP2284c hypothetical protein; PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; SPTR: uncharacterized protein; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; Zinc finger found in FPG and IleRS YP_004100845.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115: IPR004437; KEGG: cfl:Cfla_3719 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004100846.1 COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: sgr:SGR_3693 partitioning or sporulation protein; SPTR: partitioning or sporulation protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004100847.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682; KEGG: krh:KRH_23520 16S rRNA methyltransferase GidB; PFAM: glucose inhibited division protein; SPTR: ribosomal RNA small subunit methyltransferase G; TIGRFAM: methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA methyltransferase GidB YP_004100848.1 COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: kse:Ksed_27000 predicted RNA-binding protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: Jag-like protein; PFAM: R3H domain YP_004100849.1 COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001: IPR000215; KEGG: cfl:Cfla_3727 membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein; SPTR: inner membrane protein translocase component YidC; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain YP_004100850.1 COGs: COG0759 conserved hypothetical protein; InterPro IPR002696; KEGG: gct:GC56T3_0626 protein of unknown function DUF37; PFAM: protein of unknown function DUF37; SPTR: uncharacterized protein; manually curated; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD YP_004100851.1 InterPro IPR000100; KEGG: kfl:Kfla_7085 ribonuclease P protein component; PFAM: ribonuclease P protein; SPTR: ribonuclease P protein; TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_004100852.1 InterPro IPR000271: IPR020939; KEGG: nml:Namu_5415 50S ribosomal protein L34; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type