-- dump date 20140619_114205 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 512562000001 SEQ_END SEQ_END NC_010698.2 1608548 1608548 DR NC_010698.2; contig end 1608548..1608548 Helicobacter pylori Shi470 YP_001909500.1 CDS nusB NC_010698.2 11 427 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(11..427) Helicobacter pylori Shi470 6296652 YP_001909501.1 CDS ribH NC_010698.2 429 899 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(429..899) Helicobacter pylori Shi470 6296946 YP_001909502.1 CDS HPSH_00015 NC_010698.2 909 1739 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(909..1739) Helicobacter pylori Shi470 6297023 YP_001909503.1 CDS HPSH_00020 NC_010698.2 1726 2391 R COG0288 Carbonic anhydrase; beta-carbonic anhydrase complement(1726..2391) Helicobacter pylori Shi470 6296028 YP_001909504.1 CDS HPSH_00025 NC_010698.2 2514 3197 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2514..3197 Helicobacter pylori Shi470 6296030 YP_001909505.1 CDS panC NC_010698.2 3198 4028 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3198..4028 Helicobacter pylori Shi470 6296088 YP_001909506.1 CDS HPSH_00045 NC_010698.2 7229 7312 R hypothetical protein complement(7229..7312) Helicobacter pylori Shi470 6296175 YP_001909507.1 CDS groEL NC_010698.2 7356 8996 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(7356..8996) Helicobacter pylori Shi470 6296621 YP_001909508.1 CDS groES NC_010698.2 9021 9377 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(9021..9377) Helicobacter pylori Shi470 6295998 YP_001909509.1 CDS dnaG NC_010698.2 9663 11342 D synthesizes RNA primers at the replication forks; DNA primase 9663..11342 Helicobacter pylori Shi470 6296995 YP_001909510.1 CDS HPSH_00065 NC_010698.2 11339 12391 D COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; argininosuccinate synthase 11339..12391 Helicobacter pylori Shi470 6296475 YP_001909511.1 CDS HPSH_00070 NC_010698.2 12388 12498 D hypothetical protein 12388..12498 Helicobacter pylori Shi470 6296218 YP_001909512.1 CDS HPSH_00075 NC_010698.2 12483 13310 D hypothetical protein 12483..13310 Helicobacter pylori Shi470 6296376 YP_001909513.1 CDS HPSH_00080 NC_010698.2 13456 13737 D hypothetical protein 13456..13737 Helicobacter pylori Shi470 6297215 YP_001909514.1 CDS HPSH_00085 NC_010698.2 13737 14000 D hypothetical protein 13737..14000 Helicobacter pylori Shi470 6296405 YP_001909515.1 CDS HPSH_00090 NC_010698.2 14002 16365 D COG3451 Type IV secretory pathway, VirB4 components; hypothetical protein 14002..16365 Helicobacter pylori Shi470 6297112 YP_001909516.1 CDS HPSH_00095 NC_010698.2 16686 18026 D COG3014 Uncharacterized protein conserved in bacteria; hypothetical protein 16686..18026 Helicobacter pylori Shi470 6297013 YP_001909517.1 CDS HPSH_00100 NC_010698.2 18121 19086 D COG0835 Chemotaxis signal transduction protein; chemotaxis protein CheV 18121..19086 Helicobacter pylori Shi470 6296390 YP_001909518.1 CDS HPSH_00105 NC_010698.2 19083 20300 D COG0019 Diaminopimelate decarboxylase; carboxynorspermidine decarboxylase 19083..20300 Helicobacter pylori Shi470 6296449 YP_001909519.1 CDS HPSH_00110 NC_010698.2 20310 20882 R inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase complement(20310..20882) Helicobacter pylori Shi470 6296443 YP_001909520.1 CDS HPSH_00115 NC_010698.2 20893 22464 R attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase complement(20893..22464) Helicobacter pylori Shi470 6296976 YP_001909521.1 CDS HPSH_00120 NC_010698.2 22801 24867 R outer membrane protein HopD complement(22801..24867) Helicobacter pylori Shi470 6296513 YP_001909522.1 CDS HPSH_00125 NC_010698.2 25187 25312 D hypothetical protein 25187..25312 Helicobacter pylori Shi470 6296072 YP_001909523.1 CDS gltA NC_010698.2 25379 26659 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(25379..26659) Helicobacter pylori Shi470 6296862 YP_001909524.1 CDS HPSH_00135 NC_010698.2 26857 28134 D COG0538 Isocitrate dehydrogenases; isocitrate dehydrogenase (icd) 26857..28134 Helicobacter pylori Shi470 6297285 YP_001909525.1 CDS HPSH_00140 NC_010698.2 28206 28733 D hypothetical protein 28206..28733 Helicobacter pylori Shi470 6297171 YP_001909526.1 CDS HPSH_00145 NC_010698.2 28710 29366 R COG0132 Dethiobiotin synthetase; dethiobiotin synthetase complement(28710..29366) Helicobacter pylori Shi470 6296206 YP_001909527.1 CDS HPSH_00150 NC_010698.2 29370 29690 R hypothetical protein complement(29370..29690) Helicobacter pylori Shi470 6296105 YP_001909528.1 CDS HPSH_00155 NC_010698.2 29869 30282 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; hypothetical protein 29869..30282 Helicobacter pylori Shi470 6296297 YP_001909529.1 CDS HPSH_00160 NC_010698.2 30290 30565 D COG2127 Uncharacterized conserved protein; hypothetical protein 30290..30565 Helicobacter pylori Shi470 6297404 YP_001909530.1 CDS HPSH_00165 NC_010698.2 30565 32787 D COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent C1p protease ClpA 30565..32787 Helicobacter pylori Shi470 6296191 YP_001909531.1 CDS HPSH_00170 NC_010698.2 32777 33127 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 32777..33127 Helicobacter pylori Shi470 6296259 YP_001909532.1 CDS HPSH_00175 NC_010698.2 33138 33440 D COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 33138..33440 Helicobacter pylori Shi470 6296722 YP_001909533.1 CDS HPSH_00180 NC_010698.2 33440 34435 D COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; hypothetical protein 33440..34435 Helicobacter pylori Shi470 6297393 YP_001909534.1 CDS HPSH_00185 NC_010698.2 34441 35496 D NADH-ubiquinone oxidoreductase subunit 34441..35496 Helicobacter pylori Shi470 6296604 YP_001909535.1 CDS HPSH_00190 NC_010698.2 35512 35625 D comB7 putative lipoprotein 35512..35625 Helicobacter pylori Shi470 6296602 YP_001909536.1 CDS HPSH_00195 NC_010698.2 35622 36365 D COG3736 Type IV secretory pathway, component VirB8; comB8 competence protein 35622..36365 Helicobacter pylori Shi470 6296171 YP_001909537.1 CDS HPSH_00200 NC_010698.2 36365 37330 D COG3504 Type IV secretory pathway, VirB9 components; comB9 competence protein 36365..37330 Helicobacter pylori Shi470 6296613 YP_001909538.1 CDS HPSH_00205 NC_010698.2 37323 38459 D COG2948 Type IV secretory pathway, VirB10 components; comB10 competence protein 37323..38459 Helicobacter pylori Shi470 6297487 YP_001909539.1 CDS HPSH_00210 NC_010698.2 38530 39942 D COG0836 Mannose-1-phosphate guanylyltransferase; mannose-6-phosphate isomerase 38530..39942 Helicobacter pylori Shi470 6296748 YP_001909540.1 CDS HPSH_00215 NC_010698.2 39970 41115 D COG1089 GDP-D-mannose dehydratase; GDP-D-mannose dehydratase (rfbD) 39970..41115 Helicobacter pylori Shi470 6296102 YP_001909541.1 CDS HPSH_00220 NC_010698.2 41108 42040 D COG0451 Nucleoside-diphosphate-sugar epimerases; nodulation protein NolK 41108..42040 Helicobacter pylori Shi470 6297176 YP_001909542.1 CDS HPSH_00225 NC_010698.2 42120 42224 R hypothetical protein complement(42120..42224) Helicobacter pylori Shi470 6296152 YP_001909543.1 CDS HPSH_00230 NC_010698.2 42325 43323 R COG0309 Hydrogenase maturation factor; hydrogenase expression/formation protein complement(42325..43323) Helicobacter pylori Shi470 6296201 YP_001909544.1 CDS HPSH_00235 NC_010698.2 43326 45578 R COG0068 Hydrogenase maturation factor; transcriptional regulator HypF complement(43326..45578) Helicobacter pylori Shi470 6296760 YP_001909545.1 CDS HPSH_00240 NC_010698.2 45575 46567 R COG2957 Peptidylarginine deiminase and related enzymes; hypothetical protein complement(45575..46567) Helicobacter pylori Shi470 6296765 YP_001909546.1 CDS HPSH_00245 NC_010698.2 46626 47324 R COG0863 DNA modification methylase; adenine specific DNA methyltransferase complement(46626..47324) Helicobacter pylori Shi470 6296253 YP_001909547.1 CDS HPSH_00250 NC_010698.2 47321 48388 R COG0270 Site-specific DNA methylase; cytosine specific DNA methyltransferase complement(47321..48388) Helicobacter pylori Shi470 6297540 YP_001909548.1 CDS HPSH_00255 NC_010698.2 48385 48585 R hypothetical protein complement(48385..48585) Helicobacter pylori Shi470 6297532 YP_001909549.1 CDS HPSH_00260 NC_010698.2 48613 49611 R hypothetical protein complement(48613..49611) Helicobacter pylori Shi470 6296170 YP_001909550.1 CDS HPSH_00265 NC_010698.2 49652 49852 R adenine/cytosine DNA methyltransferase complement(49652..49852) Helicobacter pylori Shi470 6296433 YP_001909551.1 CDS HPSH_00270 NC_010698.2 49833 51332 R COG0591 Na+/proline symporter; proline permease PutP complement(49833..51332) Helicobacter pylori Shi470 6297152 YP_001909552.1 CDS HPSH_00275 NC_010698.2 51359 54916 R COG0506 Proline dehydrogenase; Proline/pyrroline-5-carboxylate dehydrogenase complement(51359..54916) Helicobacter pylori Shi470 6296386 YP_001909553.1 CDS HPSH_00280 NC_010698.2 55244 55453 D hypothetical protein 55244..55453 Helicobacter pylori Shi470 6296359 YP_001909554.1 CDS HPSH_00285 NC_010698.2 55564 55647 D hypothetical protein 55564..55647 Helicobacter pylori Shi470 6296484 YP_001909555.1 CDS HPSH_00290 NC_010698.2 55641 55766 R hypothetical protein complement(55641..55766) Helicobacter pylori Shi470 6296447 YP_001909556.1 CDS HPSH_00295 NC_010698.2 55951 56661 D COG5002 Signal transduction histidine kinase; hypothetical protein 55951..56661 Helicobacter pylori Shi470 6296041 YP_001909557.1 CDS HPSH_00300 NC_010698.2 56631 57056 D hypothetical protein 56631..57056 Helicobacter pylori Shi470 6297098 YP_001909558.1 CDS HPSH_00305 NC_010698.2 57058 57408 D hypothetical protein 57058..57408 Helicobacter pylori Shi470 6296578 YP_001909559.1 CDS HPSH_00320 NC_010698.2 59832 60629 R COG0829 Urease accessory protein UreH; urease accessory protein UreH complement(59832..60629) Helicobacter pylori Shi470 6296684 YP_001909560.1 CDS HPSH_00325 NC_010698.2 60629 61228 R COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; urease accessory protein complement(60629..61228) Helicobacter pylori Shi470 6296588 YP_001909561.1 CDS HPSH_00330 NC_010698.2 61257 62000 R COG0830 Urease accessory protein UreF; urease accessory protein UreF complement(61257..62000) Helicobacter pylori Shi470 6296537 YP_001909562.1 CDS ureE NC_010698.2 62029 62541 R involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE complement(62029..62541) Helicobacter pylori Shi470 6296890 YP_001909563.1 CDS HPSH_00340 NC_010698.2 62543 63130 R COG1138 Cytochrome c biogenesis factor; urea transporter complement(62543..63130) Helicobacter pylori Shi470 6295991 YP_001909564.1 CDS HPSH_00345 NC_010698.2 63198 63308 R hypothetical protein complement(63198..63308) Helicobacter pylori Shi470 6297438 YP_001909565.1 CDS ureB NC_010698.2 63323 65032 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta complement(63323..65032) Helicobacter pylori Shi470 6296092 YP_001909566.1 CDS HPSH_00355 NC_010698.2 65036 65752 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha complement(65036..65752) Helicobacter pylori Shi470 6296064 YP_001909567.1 CDS lspA NC_010698.2 66115 66588 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(66115..66588) Helicobacter pylori Shi470 6296079 YP_001909568.1 CDS glmM NC_010698.2 66582 67919 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(66582..67919) Helicobacter pylori Shi470 6296244 YP_001909569.1 CDS rpsT NC_010698.2 68009 68278 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 68009..68278 Helicobacter pylori Shi470 6296234 YP_001909570.1 CDS prfA NC_010698.2 68395 69453 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 68395..69453 Helicobacter pylori Shi470 6296800 YP_001909571.1 CDS HPSH_00380 NC_010698.2 69844 70098 D hypothetical protein 69844..70098 Helicobacter pylori Shi470 6296236 YP_001909572.1 CDS HPSH_00385 NC_010698.2 70176 71417 D outer membrane protein HorA 70176..71417 Helicobacter pylori Shi470 6296491 YP_001909573.1 CDS HPSH_00390 NC_010698.2 71672 73459 D hypothetical protein 71672..73459 Helicobacter pylori Shi470 6296060 YP_001909574.1 CDS HPSH_00395 NC_010698.2 73754 73885 D hypothetical protein 73754..73885 Helicobacter pylori Shi470 6296633 YP_001909575.1 CDS HPSH_00400 NC_010698.2 73889 75910 R COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis transducer TlpC complement(73889..75910) Helicobacter pylori Shi470 6296328 YP_001909576.1 CDS rpsI NC_010698.2 76058 76447 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(76058..76447) Helicobacter pylori Shi470 6296876 YP_001909577.1 CDS rplM NC_010698.2 76444 76869 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(76444..76869) Helicobacter pylori Shi470 6297049 YP_001909578.1 CDS HPSH_00415 NC_010698.2 76975 77079 R hypothetical protein complement(76975..77079) Helicobacter pylori Shi470 6296680 YP_001909579.1 CDS HPSH_00420 NC_010698.2 77060 77248 R hypothetical protein complement(77060..77248) Helicobacter pylori Shi470 6296098 YP_001909580.1 CDS HPSH_00425 NC_010698.2 77255 78601 R COG0579 Predicted dehydrogenase; malate:quinone oxidoreductase complement(77255..78601) Helicobacter pylori Shi470 6296945 YP_001909581.1 CDS HPSH_00430 NC_010698.2 78661 80034 R COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein complement(78661..80034) Helicobacter pylori Shi470 6296728 YP_001909582.1 CDS HPSH_00435 NC_010698.2 80054 82039 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(80054..82039) Helicobacter pylori Shi470 6296239 YP_001909583.1 CDS HPSH_00440 NC_010698.2 82230 82925 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(82230..82925) Helicobacter pylori Shi470 6297289 YP_001909584.1 CDS HPSH_00445 NC_010698.2 82936 83865 R COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl coenzyme A-acyl carrier protein transacylase complement(82936..83865) Helicobacter pylori Shi470 6296025 YP_001909585.1 CDS HPSH_00465 NC_010698.2 85119 85952 D COG0863 DNA modification methylase; type I restriction enzyme M protein HsdM 85119..85952 Helicobacter pylori Shi470 6296323 YP_001909586.1 CDS HPSH_00470 NC_010698.2 85970 86860 R alpha-1,2-fucosyltransferase complement(85970..86860) Helicobacter pylori Shi470 6296442 YP_001909587.1 CDS HPSH_00475 NC_010698.2 86959 87489 R hypothetical protein complement(86959..87489) Helicobacter pylori Shi470 6297527 YP_001909588.1 CDS HPSH_00480 NC_010698.2 87562 88506 D Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 87562..88506 Helicobacter pylori Shi470 6296488 YP_001909589.1 CDS HPSH_00485 NC_010698.2 88834 89547 R hypothetical protein complement(88834..89547) Helicobacter pylori Shi470 6297509 YP_001909590.1 CDS HPSH_00490 NC_010698.2 89652 91112 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(89652..91112) Helicobacter pylori Shi470 6296050 YP_001909591.1 CDS HPSH_00495 NC_010698.2 91315 93351 D COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein TlpA 91315..93351 Helicobacter pylori Shi470 6296051 YP_001909592.1 CDS HPSH_00500 NC_010698.2 93351 94457 D COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein 93351..94457 Helicobacter pylori Shi470 6296352 YP_001909593.1 CDS HPSH_00505 NC_010698.2 94573 95334 D hypothetical protein 94573..95334 Helicobacter pylori Shi470 6296145 YP_001909594.1 CDS HPSH_00510 NC_010698.2 95317 96099 R COG0463 Glycosyltransferases involved in cell wall biogenesis; hypothetical protein complement(95317..96099) Helicobacter pylori Shi470 6297233 YP_001909595.1 CDS HPSH_00515 NC_010698.2 96130 97827 R COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein TlpB complement(96130..97827) Helicobacter pylori Shi470 6296099 YP_001909596.1 CDS HPSH_00520 NC_010698.2 98036 99781 R COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; 2',3'-cyclic-nucleotide 2'-phosphodiesterase complement(98036..99781) Helicobacter pylori Shi470 6296516 YP_001909597.1 CDS HPSH_00525 NC_010698.2 99921 100388 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(99921..100388) Helicobacter pylori Shi470 6296483 YP_001909598.1 CDS HPSH_00530 NC_010698.2 100423 101565 R catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase/cystathionine beta-lyase complement(100423..101565) Helicobacter pylori Shi470 6297288 YP_001909599.1 CDS HPSH_00535 NC_010698.2 101586 102503 R COG0031 Cysteine synthase; cysteine synthetase complement(101586..102503) Helicobacter pylori Shi470 6296751 YP_001909600.1 CDS dnaK NC_010698.2 103322 105184 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(103322..105184) Helicobacter pylori Shi470 6296279 YP_001909601.1 CDS HPSH_00555 NC_010698.2 105215 105790 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(105215..105790) Helicobacter pylori Shi470 6296268 YP_001909602.1 CDS HPSH_00560 NC_010698.2 105790 106620 R Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor complement(105790..106620) Helicobacter pylori Shi470 6297183 YP_001909603.1 CDS HPSH_00565 NC_010698.2 106915 107478 D COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; hypothetical protein 106915..107478 Helicobacter pylori Shi470 6296372 YP_001909604.1 CDS HPSH_00570 NC_010698.2 107500 107796 D hypothetical protein 107500..107796 Helicobacter pylori Shi470 6296343 YP_001909605.1 CDS HPSH_00575 NC_010698.2 107821 109704 R COG2604 Uncharacterized protein conserved in bacteria; hypothetical protein complement(107821..109704) Helicobacter pylori Shi470 6296807 YP_001909606.1 CDS HPSH_00580 NC_010698.2 109767 111311 R FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B complement(109767..111311) Helicobacter pylori Shi470 6296868 YP_001909607.1 CDS HPSH_00585 NC_010698.2 111477 113687 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 111477..113687 Helicobacter pylori Shi470 6296047 YP_001909608.1 CDS HPSH_00590 NC_010698.2 113677 114606 D COG0731 Fe-S oxidoreductases; hypothetical protein 113677..114606 Helicobacter pylori Shi470 6296161 YP_001909609.1 CDS HPSH_00595 NC_010698.2 114756 115994 R hypothetical protein complement(114756..115994) Helicobacter pylori Shi470 6296548 YP_001909610.1 CDS HPSH_00600 NC_010698.2 116278 117291 R hypothetical protein complement(116278..117291) Helicobacter pylori Shi470 6296439 YP_001909611.1 CDS HPSH_00605 NC_010698.2 117391 119829 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(117391..119829) Helicobacter pylori Shi470 6297484 YP_001909612.1 CDS HPSH_00610 NC_010698.2 120035 120148 D hypothetical protein 120035..120148 Helicobacter pylori Shi470 6296324 YP_001909613.1 CDS thrS NC_010698.2 120189 122027 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 120189..122027 Helicobacter pylori Shi470 6296270 YP_001909614.1 CDS infC NC_010698.2 122024 122635 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 122024..122635 Helicobacter pylori Shi470 6296336 YP_001909615.1 CDS rpmI NC_010698.2 122616 122810 D COG0291 Ribosomal protein L35; 50S ribosomal protein L35 122616..122810 Helicobacter pylori Shi470 6296436 YP_001909616.1 CDS rplT NC_010698.2 122905 123255 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 122905..123255 Helicobacter pylori Shi470 6296147 YP_001909617.1 CDS HPSH_00635 NC_010698.2 123466 124326 D outer membrane protein HorB 123466..124326 Helicobacter pylori Shi470 6296952 YP_001909618.1 CDS HPSH_00640 NC_010698.2 124378 124500 D hypothetical protein 124378..124500 Helicobacter pylori Shi470 6296349 YP_001909619.1 CDS HPSH_00645 NC_010698.2 124678 125109 D hypothetical protein 124678..125109 Helicobacter pylori Shi470 6296477 YP_001909620.1 CDS HPSH_00650 NC_010698.2 125513 126382 D hypothetical protein 125513..126382 Helicobacter pylori Shi470 6296130 YP_001909621.1 CDS HPSH_00655 NC_010698.2 126812 127012 D hypothetical protein 126812..127012 Helicobacter pylori Shi470 6296989 YP_001909622.1 CDS HPSH_00660 NC_010698.2 127248 128615 R COG1760 L-serine deaminase; L-serine deaminase complement(127248..128615) Helicobacter pylori Shi470 6297031 YP_001909623.1 CDS HPSH_00665 NC_010698.2 128615 129856 R COG0814 Amino acid permeases; hypothetical protein complement(128615..129856) Helicobacter pylori Shi470 6296541 YP_001909624.1 CDS HPSH_00670 NC_010698.2 129919 130011 D hypothetical protein 129919..130011 Helicobacter pylori Shi470 6296318 YP_001909625.1 CDS HPSH_00675 NC_010698.2 130038 131387 D COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; tyrosine-regulated 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 130038..131387 Helicobacter pylori Shi470 6296539 YP_001909626.1 CDS HPSH_00680 NC_010698.2 131466 131600 D hypothetical protein 131466..131600 Helicobacter pylori Shi470 6296473 YP_001909627.1 CDS HPSH_00685 NC_010698.2 131829 132287 R COG1225 Peroxiredoxin; bacterioferritin comigratory protein complement(131829..132287) Helicobacter pylori Shi470 6296465 YP_001909628.1 CDS HPSH_00690 NC_010698.2 132297 132932 R COG1556 Uncharacterized conserved protein; hypothetical protein complement(132297..132932) Helicobacter pylori Shi470 6296503 YP_001909629.1 CDS HPSH_00695 NC_010698.2 132925 134370 R COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain; iron-sulfur protein complement(132925..134370) Helicobacter pylori Shi470 6296002 YP_001909630.1 CDS HPSH_00700 NC_010698.2 134399 135127 R COG0247 Fe-S oxidoreductase; hypothetical protein complement(134399..135127) Helicobacter pylori Shi470 6296331 YP_001909631.1 CDS HPSH_00705 NC_010698.2 135348 136997 D COG1620 L-lactate permease; L-lactate permease 135348..136997 Helicobacter pylori Shi470 6296456 YP_001909632.1 CDS HPSH_00710 NC_010698.2 137046 138701 D COG1620 L-lactate permease; L-lactate permease 137046..138701 Helicobacter pylori Shi470 6296344 YP_001909633.1 CDS HPSH_00715 NC_010698.2 138725 139594 R COG1194 A/G-specific DNA glycosylase; DNA glycosylase MutY complement(138725..139594) Helicobacter pylori Shi470 6296046 YP_001909634.1 CDS HPSH_00720 NC_010698.2 139712 141160 R COG0471 Di- and tricarboxylate transporters; C(4)-dicarboxylates and tricarboxylates/succinate antiporter complement(139712..141160) Helicobacter pylori Shi470 6296406 YP_001909635.1 CDS HPSH_00725 NC_010698.2 141330 142796 D CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 141330..142796 Helicobacter pylori Shi470 6296472 YP_001909636.1 CDS HPSH_00730 NC_010698.2 142809 143507 D CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 142809..143507 Helicobacter pylori Shi470 6296356 YP_001909637.1 CDS HPSH_00735 NC_010698.2 143518 143736 D cbb3-type cytochrome c oxidase subunit Q CcoQ 143518..143736 Helicobacter pylori Shi470 6296431 YP_001909638.1 CDS HPSH_00740 NC_010698.2 143738 144616 D COG2010 Cytochrome c, mono- and diheme variants; cytochrome c oxidase diheme subunit 143738..144616 Helicobacter pylori Shi470 6296740 YP_001909639.1 CDS HPSH_00745 NC_010698.2 144627 144833 D hypothetical protein 144627..144833 Helicobacter pylori Shi470 6296292 YP_001909640.1 CDS HPSH_00750 NC_010698.2 144830 144937 D hypothetical protein 144830..144937 Helicobacter pylori Shi470 6296766 YP_001909641.1 CDS HPSH_00755 NC_010698.2 144973 145518 D COG0443 Molecular chaperone; hypothetical protein 144973..145518 Helicobacter pylori Shi470 6296429 YP_001909642.1 CDS HPSH_00760 NC_010698.2 145530 146111 D hypothetical protein 145530..146111 Helicobacter pylori Shi470 6296818 YP_001909643.1 CDS HPSH_00765 NC_010698.2 146200 146967 D hypothetical protein 146200..146967 Helicobacter pylori Shi470 6296476 YP_001909644.1 CDS HPSH_00770 NC_010698.2 146964 147830 R COG2107 Predicted periplasmic solute-binding protein; hypothetical protein complement(146964..147830) Helicobacter pylori Shi470 6296495 YP_001909645.1 CDS recA NC_010698.2 147929 148972 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 147929..148972 Helicobacter pylori Shi470 6296515 YP_001909646.1 CDS eno NC_010698.2 148984 150264 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 148984..150264 Helicobacter pylori Shi470 6296811 YP_001909647.1 CDS HPSH_00785 NC_010698.2 150257 150532 D hypothetical protein 150257..150532 Helicobacter pylori Shi470 6295995 YP_001909648.1 CDS HPSH_00790 NC_010698.2 150548 151144 D hypothetical protein 150548..151144 Helicobacter pylori Shi470 6296317 YP_001909649.1 CDS aroK NC_010698.2 151149 151637 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 151149..151637 Helicobacter pylori Shi470 6296222 YP_001909650.1 CDS HPSH_00800 NC_010698.2 151658 152614 D hypothetical protein 151658..152614 Helicobacter pylori Shi470 6296131 YP_001909651.1 CDS HPSH_00805 NC_010698.2 152611 153723 R COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; putative lipopolysaccharide biosynthesis protein complement(152611..153723) Helicobacter pylori Shi470 6296167 YP_001909652.1 CDS HPSH_00810 NC_010698.2 153874 154791 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 153874..154791 Helicobacter pylori Shi470 6296859 YP_001909653.1 CDS HPSH_00815 NC_010698.2 155240 155371 R hypothetical protein complement(155240..155371) Helicobacter pylori Shi470 6296711 YP_001909654.1 CDS HPSH_00820 NC_010698.2 155550 156272 R COG0217 Uncharacterized conserved protein; hypothetical protein complement(155550..156272) Helicobacter pylori Shi470 6296211 YP_001909655.1 CDS HPSH_00825 NC_010698.2 156273 157244 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(156273..157244) Helicobacter pylori Shi470 6296412 YP_001909656.1 CDS HPSH_00830 NC_010698.2 157267 158598 R COG0642 Signal transduction histidine kinase; putative histidine kinase sensor protein complement(157267..158598) Helicobacter pylori Shi470 6297186 YP_001909657.1 CDS HPSH_00835 NC_010698.2 158624 159301 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator OmpR complement(158624..159301) Helicobacter pylori Shi470 6297272 YP_001909658.1 CDS HPSH_00840 NC_010698.2 159535 159999 R hypothetical protein complement(159535..159999) Helicobacter pylori Shi470 6296518 YP_001909659.1 CDS HPSH_00845 NC_010698.2 159990 160253 R COG0457 FOG: TPR repeat; hypothetical protein complement(159990..160253) Helicobacter pylori Shi470 6296035 YP_001909660.1 CDS HPSH_00850 NC_010698.2 160286 161566 R COG0826 Collagenase and related proteases; collagenase complement(160286..161566) Helicobacter pylori Shi470 6296309 YP_001909661.1 CDS HPSH_00855 NC_010698.2 161569 162288 R hypothetical protein complement(161569..162288) Helicobacter pylori Shi470 6296217 YP_001909662.1 CDS prfB NC_010698.2 162363 163454 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(162363..163454) Helicobacter pylori Shi470 6296320 YP_001909663.1 CDS HPSH_00865 NC_010698.2 163515 164690 R COG0303 Molybdopterin biosynthesis enzyme; molybdopterin biosynthesis protein MoeA complement(163515..164690) Helicobacter pylori Shi470 6296394 YP_001909664.1 CDS fliR NC_010698.2 164700 165467 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(164700..165467) Helicobacter pylori Shi470 6296467 YP_001909665.1 CDS HPSH_00875 NC_010698.2 165442 166188 R hypothetical protein complement(165442..166188) Helicobacter pylori Shi470 6296315 YP_001909666.1 CDS HPSH_00880 NC_010698.2 166669 167568 D COG0760 Parvulin-like peptidyl-prolyl isomerase; putative peptidyl-prolyl cis-trans isomerase 166669..167568 Helicobacter pylori Shi470 6296479 YP_001909667.1 CDS HPSH_00885 NC_010698.2 167585 168508 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 167585..168508 Helicobacter pylori Shi470 6296538 YP_001909668.1 CDS HPSH_00890 NC_010698.2 168530 169093 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 168530..169093 Helicobacter pylori Shi470 6297388 YP_001909669.1 CDS HPSH_00895 NC_010698.2 169315 169437 D hypothetical protein 169315..169437 Helicobacter pylori Shi470 6296559 YP_001909670.1 CDS HPSH_00900 NC_010698.2 169636 170658 R COG2089 Sialic acid synthase; sialic acid synthase complement(169636..170658) Helicobacter pylori Shi470 6296614 YP_001909671.1 CDS HPSH_00905 NC_010698.2 170662 171303 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein complement(170662..171303) Helicobacter pylori Shi470 6296523 YP_001909672.1 CDS HPSH_00910 NC_010698.2 171303 172577 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(171303..172577) Helicobacter pylori Shi470 6296530 YP_001909673.1 CDS HPSH_00915 NC_010698.2 172678 172830 D hypothetical protein 172678..172830 Helicobacter pylori Shi470 6296761 YP_001909674.1 CDS HPSH_00920 NC_010698.2 172827 173528 D COG1286 Uncharacterized membrane protein, required for colicin V production; hypothetical protein 172827..173528 Helicobacter pylori Shi470 6296141 YP_001909675.1 CDS lysS NC_010698.2 173538 175043 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 173538..175043 Helicobacter pylori Shi470 6297477 YP_001909676.1 CDS glyA NC_010698.2 175043 176293 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 175043..176293 Helicobacter pylori Shi470 6296460 YP_001909677.1 CDS HPSH_00935 NC_010698.2 176304 176846 D hypothetical protein 176304..176846 Helicobacter pylori Shi470 6296420 YP_001909678.1 CDS HPSH_00940 NC_010698.2 176868 177677 D hypothetical protein 176868..177677 Helicobacter pylori Shi470 6296049 YP_001909679.1 CDS HPSH_00945 NC_010698.2 177878 178063 R hypothetical protein complement(177878..178063) Helicobacter pylori Shi470 6297225 YP_001909680.1 CDS HPSH_00965 NC_010698.2 179667 179768 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(179667..179768) Helicobacter pylori Shi470 6296326 YP_001909681.1 CDS HPSH_00970 NC_010698.2 179931 180467 D COG2862 Predicted membrane protein; hypothetical protein 179931..180467 Helicobacter pylori Shi470 6296364 YP_001909682.1 CDS HPSH_00975 NC_010698.2 180473 181981 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; hypothetical protein complement(180473..181981) Helicobacter pylori Shi470 6296936 YP_001909683.1 CDS frdB NC_010698.2 182003 182740 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(182003..182740) Helicobacter pylori Shi470 6296863 YP_001909684.1 CDS HPSH_00985 NC_010698.2 182733 184877 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(182733..184877) Helicobacter pylori Shi470 6297003 YP_001909685.1 CDS HPSH_00990 NC_010698.2 184887 185654 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit complement(184887..185654) Helicobacter pylori Shi470 6296287 YP_001909686.1 CDS tpiA NC_010698.2 185868 186572 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 185868..186572 Helicobacter pylori Shi470 6297505 YP_001909687.1 CDS HPSH_01000 NC_010698.2 186582 187409 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 186582..187409 Helicobacter pylori Shi470 6296115 YP_001909688.1 CDS lpxD NC_010698.2 187419 188429 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 187419..188429 Helicobacter pylori Shi470 6297005 YP_001909689.1 CDS HPSH_01010 NC_010698.2 188494 189651 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 188494..189651 Helicobacter pylori Shi470 6296086 YP_001909690.1 CDS ndk NC_010698.2 189718 190131 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 189718..190131 Helicobacter pylori Shi470 6297459 YP_001909691.1 CDS HPSH_01020 NC_010698.2 190156 190512 D hypothetical protein 190156..190512 Helicobacter pylori Shi470 6296038 YP_001909692.1 CDS rpmF NC_010698.2 190528 190674 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 190528..190674 Helicobacter pylori Shi470 6296470 YP_001909693.1 CDS HPSH_01030 NC_010698.2 190742 191761 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 190742..191761 Helicobacter pylori Shi470 6296275 YP_001909694.1 CDS HPSH_01035 NC_010698.2 191785 192780 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 191785..192780 Helicobacter pylori Shi470 6296199 YP_001909695.1 CDS HPSH_01040 NC_010698.2 192802 193104 D hypothetical protein 192802..193104 Helicobacter pylori Shi470 6296280 YP_001909696.1 CDS HPSH_01045 NC_010698.2 193388 193771 R hypothetical protein complement(193388..193771) Helicobacter pylori Shi470 6296329 YP_001909697.1 CDS HPSH_01065 NC_010698.2 197050 198156 D COG0489 ATPases involved in chromosome partitioning; ATP-binding protein 197050..198156 Helicobacter pylori Shi470 6296063 YP_001909698.1 CDS HPSH_01070 NC_010698.2 198172 199191 R COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glycosyltransferase complement(198172..199191) Helicobacter pylori Shi470 6296273 YP_001909699.1 CDS HPSH_01075 NC_010698.2 199215 199328 R lipopolysaccharide 1,2-glycosyltransferase complement(199215..199328) Helicobacter pylori Shi470 6296510 YP_001909700.1 CDS HPSH_01080 NC_010698.2 199437 200840 D hypothetical protein 199437..200840 Helicobacter pylori Shi470 6296195 YP_001909701.1 CDS HPSH_01085 NC_010698.2 200943 202808 D molecular chaperone; heat shock protein 90 200943..202808 Helicobacter pylori Shi470 6297118 YP_001909702.1 CDS HPSH_01090 NC_010698.2 203212 203964 R COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein A complement(203212..203964) Helicobacter pylori Shi470 6296227 YP_001909703.1 CDS HPSH_01095 NC_010698.2 204050 205201 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(204050..205201) Helicobacter pylori Shi470 6296462 YP_001909704.1 CDS HPSH_01100 NC_010698.2 205212 207077 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(205212..207077) Helicobacter pylori Shi470 6296384 YP_001909705.1 CDS HPSH_01105 NC_010698.2 207173 208831 D COG0471 Di- and tricarboxylate transporters; sodium-dependent transporter 207173..208831 Helicobacter pylori Shi470 6296430 YP_001909706.1 CDS HPSH_01110 NC_010698.2 208844 209644 D COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthetase CdsA 208844..209644 Helicobacter pylori Shi470 6296377 YP_001909707.1 CDS HPSH_01115 NC_010698.2 209645 210751 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 209645..210751 Helicobacter pylori Shi470 6296056 YP_001909708.1 CDS HPSH_01120 NC_010698.2 210802 211098 D hypothetical protein 210802..211098 Helicobacter pylori Shi470 6296097 YP_001909709.1 CDS HPSH_01125 NC_010698.2 211146 211940 D hypothetical protein 211146..211940 Helicobacter pylori Shi470 6295994 YP_001909710.1 CDS HPSH_01130 NC_010698.2 211956 212540 R COG1881 Phospholipid-binding protein; phospholipid-binding protein complement(211956..212540) Helicobacter pylori Shi470 6297445 YP_001909711.1 CDS HPSH_01135 NC_010698.2 212652 213113 D hypothetical protein 212652..213113 Helicobacter pylori Shi470 6296032 YP_001909712.1 CDS HPSH_01140 NC_010698.2 213286 214449 D COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine desulfurase 213286..214449 Helicobacter pylori Shi470 6296733 YP_001909713.1 CDS HPSH_01145 NC_010698.2 214471 215451 D COG0822 NifU homolog involved in Fe-S cluster formation; nifU-like protein 214471..215451 Helicobacter pylori Shi470 6296096 YP_001909714.1 CDS HPSH_01150 NC_010698.2 215626 215859 D hypothetical protein 215626..215859 Helicobacter pylori Shi470 6296095 YP_001909715.1 CDS HPSH_01155 NC_010698.2 215972 217318 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 215972..217318 Helicobacter pylori Shi470 6296564 YP_001909716.1 CDS HPSH_01160 NC_010698.2 217455 218492 D COG0225 Peptide methionine sulfoxide reductase; bifunctional methionine sulfoxide reductase A/B protein 217455..218492 Helicobacter pylori Shi470 6296173 YP_001909717.1 CDS HPSH_01165 NC_010698.2 218739 218825 D hypothetical protein 218739..218825 Helicobacter pylori Shi470 6296891 YP_001909718.1 CDS HPSH_01170 NC_010698.2 218946 219779 R COG0730 Predicted permeases; hypothetical protein complement(218946..219779) Helicobacter pylori Shi470 6296504 YP_001909719.1 CDS HPSH_01175 NC_010698.2 219805 219963 R hypothetical protein complement(219805..219963) Helicobacter pylori Shi470 6296637 YP_001909720.1 CDS HPSH_01180 NC_010698.2 219985 222072 R putative Outer membrane protein complement(219985..222072) Helicobacter pylori Shi470 6296981 YP_001909721.1 CDS HPSH_01185 NC_010698.2 222329 223486 D COG0659 Sulfate permease and related transporters (MFS superfamily); putative sulfate permease 222329..223486 Helicobacter pylori Shi470 6296572 YP_001909722.1 CDS HPSH_01190 NC_010698.2 223726 225147 R outer membrane protein complement(223726..225147) Helicobacter pylori Shi470 6296656 YP_001909723.1 CDS HPSH_01195 NC_010698.2 225372 226097 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(225372..226097) Helicobacter pylori Shi470 6296363 YP_001909724.1 CDS HPSH_01200 NC_010698.2 226210 227007 D COG1651 Protein-disulfide isomerase; hypothetical protein 226210..227007 Helicobacter pylori Shi470 6296193 YP_001909725.1 CDS HPSH_01205 NC_010698.2 227023 227676 D hypothetical protein 227023..227676 Helicobacter pylori Shi470 6296120 YP_001909726.1 CDS HPSH_01210 NC_010698.2 227701 228873 D COG0754 Glutathionylspermidine synthase; hypothetical protein 227701..228873 Helicobacter pylori Shi470 6296156 YP_001909727.1 CDS HPSH_01215 NC_010698.2 228885 229403 D hypothetical protein 228885..229403 Helicobacter pylori Shi470 6296400 YP_001909728.1 CDS HPSH_01220 NC_010698.2 229499 229576 D hypothetical protein 229499..229576 Helicobacter pylori Shi470 6296374 YP_001909729.1 CDS HPSH_01225 NC_010698.2 229851 230918 R COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein E complement(229851..230918) Helicobacter pylori Shi470 6296062 YP_001909730.1 CDS HPSH_01230 NC_010698.2 231012 231380 R hypothetical protein complement(231012..231380) Helicobacter pylori Shi470 6296582 YP_001909731.1 CDS hemC NC_010698.2 231380 232300 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(231380..232300) Helicobacter pylori Shi470 6296459 YP_001909732.1 CDS HPSH_01240 NC_010698.2 232311 234044 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(232311..234044) Helicobacter pylori Shi470 6296415 YP_001909733.1 CDS hemA NC_010698.2 234048 235397 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(234048..235397) Helicobacter pylori Shi470 6297082 YP_001909734.1 CDS HPSH_01250 NC_010698.2 235397 236320 R COG0142 Geranylgeranyl pyrophosphate synthase; putative octaprenyl-diphosphate synthase complement(235397..236320) Helicobacter pylori Shi470 6296369 YP_001909735.1 CDS HPSH_01255 NC_010698.2 236330 236725 R hypothetical protein complement(236330..236725) Helicobacter pylori Shi470 6296461 YP_001909736.1 CDS HPSH_01260 NC_010698.2 236718 237002 R hypothetical protein complement(236718..237002) Helicobacter pylori Shi470 6297426 YP_001909737.1 CDS HPSH_01265 NC_010698.2 237023 237457 R COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); neutrophil activating protein NapA complement(237023..237457) Helicobacter pylori Shi470 6296517 YP_001909738.1 CDS HPSH_01270 NC_010698.2 237662 238807 R COG0642 Signal transduction histidine kinase; histidine kinase sensor protein complement(237662..238807) Helicobacter pylori Shi470 6297465 YP_001909739.1 CDS HPSH_01275 NC_010698.2 238804 239121 R hypothetical protein complement(238804..239121) Helicobacter pylori Shi470 6296367 YP_001909740.1 CDS flgI NC_010698.2 239118 240137 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(239118..240137) Helicobacter pylori Shi470 6296075 YP_001909741.1 CDS HPSH_01285 NC_010698.2 240335 241813 D COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase 240335..241813 Helicobacter pylori Shi470 6296037 YP_001909742.1 CDS HPSH_01290 NC_010698.2 241834 242922 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 241834..242922 Helicobacter pylori Shi470 6296445 YP_001909743.1 CDS HPSH_01295 NC_010698.2 242929 243468 D hypothetical protein 242929..243468 Helicobacter pylori Shi470 6296154 YP_001909744.1 CDS HPSH_01300 NC_010698.2 243532 245082 R COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; oligopeptide permease ATPase complement(243532..245082) Helicobacter pylori Shi470 6296402 YP_001909745.1 CDS HPSH_01305 NC_010698.2 245092 246114 R COG4239 ABC-type uncharacterized transport system, permease component; oligopeptide permease integral membrane protein complement(245092..246114) Helicobacter pylori Shi470 6296432 YP_001909746.1 CDS HPSH_01310 NC_010698.2 246400 246498 D hypothetical protein 246400..246498 Helicobacter pylori Shi470 6297478 YP_001909747.1 CDS HPSH_01315 NC_010698.2 246479 247900 D outer membrane protein 246479..247900 Helicobacter pylori Shi470 6297491 YP_001909748.1 CDS HPSH_01320 NC_010698.2 247952 249331 D outer membrane protein HopG 247952..249331 Helicobacter pylori Shi470 6297036 YP_001909749.1 CDS HPSH_01325 NC_010698.2 249430 250665 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 249430..250665 Helicobacter pylori Shi470 6297162 YP_001909750.1 CDS HPSH_01330 NC_010698.2 250662 251090 D hypothetical protein 250662..251090 Helicobacter pylori Shi470 6296927 YP_001909751.1 CDS HPSH_01335 NC_010698.2 251083 251742 D COG3334 Uncharacterized conserved protein; hypothetical protein 251083..251742 Helicobacter pylori Shi470 6296662 YP_001909752.1 CDS HPSH_01340 NC_010698.2 251739 252794 D COG0750 Predicted membrane-associated Zn-dependent proteases 1; hypothetical protein 251739..252794 Helicobacter pylori Shi470 6296353 YP_001909753.1 CDS xseA NC_010698.2 252807 254069 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 252807..254069 Helicobacter pylori Shi470 6296715 YP_001909754.1 CDS HPSH_01350 NC_010698.2 254088 255260 R COG2189 Adenine specific DNA methylase Mod; type II DNA modification methyltransferase complement(254088..255260) Helicobacter pylori Shi470 6296434 YP_001909755.1 CDS HPSH_01365 NC_010698.2 256055 256750 D endonuclease MjaVIP 256055..256750 Helicobacter pylori Shi470 6297541 YP_001909756.1 CDS HPSH_01370 NC_010698.2 256747 257505 D COG0863 DNA modification methylase; adenine specific DNA methyltransferase 256747..257505 Helicobacter pylori Shi470 6296091 YP_001909757.1 CDS HPSH_01375 NC_010698.2 257578 260148 D COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent protease binding subunit ClpB 257578..260148 Helicobacter pylori Shi470 6296000 YP_001909758.1 CDS HPSH_01380 NC_010698.2 260205 260924 D COG0785 Cytochrome c biogenesis protein; cytochrome c biogenesis protein 260205..260924 Helicobacter pylori Shi470 6296450 YP_001909759.1 CDS HPSH_01385 NC_010698.2 260934 262070 D COG0044 Dihydroorotase and related cyclic amidohydrolases; dihydroorotase PyrC 260934..262070 Helicobacter pylori Shi470 6296011 YP_001909760.1 CDS HPSH_01390 NC_010698.2 262055 263284 D Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 262055..263284 Helicobacter pylori Shi470 6296058 YP_001909761.1 CDS HPSH_01395 NC_010698.2 263345 263587 D hypothetical protein 263345..263587 Helicobacter pylori Shi470 6296181 YP_001909762.1 CDS HPSH_01400 NC_010698.2 263630 264910 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 263630..264910 Helicobacter pylori Shi470 6296101 YP_001909763.1 CDS HPSH_01405 NC_010698.2 264950 265603 D COG2121 Uncharacterized protein conserved in bacteria; hypothetical protein 264950..265603 Helicobacter pylori Shi470 6296018 YP_001909764.1 CDS HPSH_01410 NC_010698.2 265596 266576 D hypothetical protein 265596..266576 Helicobacter pylori Shi470 6296294 YP_001909765.1 CDS HPSH_01415 NC_010698.2 266557 267099 D hypothetical protein 266557..267099 Helicobacter pylori Shi470 6296300 YP_001909766.1 CDS HPSH_01420 NC_010698.2 267096 267635 D hypothetical protein 267096..267635 Helicobacter pylori Shi470 6296360 YP_001909767.1 CDS HPSH_01425 NC_010698.2 267651 268049 D COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 267651..268049 Helicobacter pylori Shi470 6296926 YP_001909768.1 CDS HPSH_01430 NC_010698.2 268086 269378 D COG0457 FOG: TPR repeat; ATP-dependent nuclease 268086..269378 Helicobacter pylori Shi470 6296202 YP_001909769.1 CDS HPSH_01435 NC_010698.2 269366 269923 D COG0134 Indole-3-glycerol phosphate synthase; hypothetical protein 269366..269923 Helicobacter pylori Shi470 6296160 YP_001909770.1 CDS HPSH_01440 NC_010698.2 269980 270234 D COG1145 Ferredoxin; ferredoxin 269980..270234 Helicobacter pylori Shi470 6296820 YP_001909771.1 CDS HPSH_01445 NC_010698.2 270244 271698 D COG0248 Exopolyphosphatase; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase 270244..271698 Helicobacter pylori Shi470 6296492 YP_001909772.1 CDS HPSH_01450 NC_010698.2 271695 272705 D COG0859 ADP-heptose:LPS heptosyltransferase; lipopolysaccharide heptosyltransferase-1 271695..272705 Helicobacter pylori Shi470 6296961 YP_001909773.1 CDS HPSH_01455 NC_010698.2 272702 273688 D acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 272702..273688 Helicobacter pylori Shi470 6296289 YP_001909774.1 CDS tgt NC_010698.2 273744 274859 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(273744..274859) Helicobacter pylori Shi470 6296585 YP_001909775.1 CDS HPSH_01465 NC_010698.2 274916 276352 D COG3400 Uncharacterized protein conserved in bacteria; hypothetical protein 274916..276352 Helicobacter pylori Shi470 6296732 YP_001909776.1 CDS aroB NC_010698.2 276357 277388 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 276357..277388 Helicobacter pylori Shi470 6297578 YP_001909777.1 CDS HPSH_01475 NC_010698.2 277379 278944 D COG0668 Small-conductance mechanosensitive channel; hypothetical protein 277379..278944 Helicobacter pylori Shi470 6296874 YP_001909778.1 CDS HPSH_01480 NC_010698.2 278941 280197 D COG0621 2-methylthioadenine synthetase; hypothetical protein 278941..280197 Helicobacter pylori Shi470 6296393 YP_001909779.1 CDS HPSH_01485 NC_010698.2 280184 281836 D COG0465 ATP-dependent Zn proteases; cell division protein FtsH 280184..281836 Helicobacter pylori Shi470 6296522 YP_001909780.1 CDS HPSH_01490 NC_010698.2 281839 282357 D hypothetical protein 281839..282357 Helicobacter pylori Shi470 6297160 YP_001909781.1 CDS HPSH_01495 NC_010698.2 282370 282843 D hypothetical protein 282370..282843 Helicobacter pylori Shi470 6296258 YP_001909782.1 CDS HPSH_01500 NC_010698.2 282908 291607 D toxin-like outer membrane protein 282908..291607 Helicobacter pylori Shi470 6297010 YP_001909783.1 CDS HPSH_01505 NC_010698.2 291655 292872 D COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 291655..292872 Helicobacter pylori Shi470 6296008 YP_001909784.1 CDS HPSH_01510 NC_010698.2 292877 293167 D COG1605 Chorismate mutase; hypothetical protein 292877..293167 Helicobacter pylori Shi470 6296351 YP_001909785.1 CDS HPSH_01515 NC_010698.2 293180 294052 D COG4866 Uncharacterized conserved protein; hypothetical protein 293180..294052 Helicobacter pylori Shi470 6296040 YP_001909786.1 CDS HPSH_01520 NC_010698.2 294053 295732 D COG0147 Anthranilate/para-aminobenzoate synthases component I; para-aminobenzoate synthetase PabB 294053..295732 Helicobacter pylori Shi470 6296368 YP_001909787.1 CDS amiE NC_010698.2 295918 296937 D aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 295918..296937 Helicobacter pylori Shi470 6296610 YP_001909788.1 CDS flgL NC_010698.2 297020 299506 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL complement(297020..299506) Helicobacter pylori Shi470 6297374 YP_001909789.1 CDS rplU NC_010698.2 299726 300040 D COG0261 Ribosomal protein L21; 50S ribosomal protein L21 299726..300040 Helicobacter pylori Shi470 6296448 YP_001909790.1 CDS rpmA NC_010698.2 300055 300321 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 300055..300321 Helicobacter pylori Shi470 6296228 YP_001909791.1 CDS HPSH_01545 NC_010698.2 300438 302087 D COG0747 ABC-type dipeptide transport system, periplasmic component; periplasmic dipeptide-binding protein 300438..302087 Helicobacter pylori Shi470 6296401 YP_001909792.1 CDS HPSH_01550 NC_010698.2 302098 303102 D COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide permease 302098..303102 Helicobacter pylori Shi470 6296208 YP_001909793.1 CDS HPSH_01555 NC_010698.2 303102 303959 D COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide permease 303102..303959 Helicobacter pylori Shi470 6296427 YP_001909794.1 CDS HPSH_01560 NC_010698.2 303971 304834 D COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; dipeptide ABC transporter ATP-binding protein DppD 303971..304834 Helicobacter pylori Shi470 6296593 YP_001909795.1 CDS HPSH_01565 NC_010698.2 304831 305637 D COG4608 ABC-type oligopeptide transport system, ATPase component; dipeptide transport system atp-binding protein 304831..305637 Helicobacter pylori Shi470 6296546 YP_001909796.1 CDS obgE NC_010698.2 305657 306739 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 305657..306739 Helicobacter pylori Shi470 6296155 YP_001909797.1 CDS HPSH_01575 NC_010698.2 306781 307776 D hypothetical protein 306781..307776 Helicobacter pylori Shi470 6296501 YP_001909798.1 CDS HPSH_01580 NC_010698.2 308024 308578 D hypothetical protein 308024..308578 Helicobacter pylori Shi470 6296511 YP_001909799.1 CDS HPSH_01585 NC_010698.2 308588 309880 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 308588..309880 Helicobacter pylori Shi470 6297135 YP_001909800.1 CDS HPSH_01590 NC_010698.2 309885 310142 D hypothetical protein 309885..310142 Helicobacter pylori Shi470 6296370 YP_001909801.1 CDS HPSH_01595 NC_010698.2 310158 310562 D hypothetical protein 310158..310562 Helicobacter pylori Shi470 6297108 YP_001909802.1 CDS HPSH_01600 NC_010698.2 310646 311530 D COG0388 Predicted amidohydrolase; hypothetical protein 310646..311530 Helicobacter pylori Shi470 6296651 YP_001909803.1 CDS HPSH_01615 NC_010698.2 312479 313171 R type II restriction enzyme complement(312479..313171) Helicobacter pylori Shi470 6296661 YP_001909804.1 CDS HPSH_01620 NC_010698.2 313182 314291 R COG0863 DNA modification methylase; DNA methylase complement(313182..314291) Helicobacter pylori Shi470 6296381 YP_001909805.1 CDS HPSH_01625 NC_010698.2 314387 314743 D hypothetical protein 314387..314743 Helicobacter pylori Shi470 6297534 YP_001909806.1 CDS HPSH_01630 NC_010698.2 314743 315705 D COG0523 Putative GTPases (G3E family); ATP-binding protein 314743..315705 Helicobacter pylori Shi470 6296281 YP_001909807.1 CDS HPSH_01635 NC_010698.2 315711 316856 R COG0477 Permeases of the major facilitator superfamily; nitrite extrusion protein NarK complement(315711..316856) Helicobacter pylori Shi470 6296298 YP_001909808.1 CDS HPSH_01640 NC_010698.2 317180 317260 D hypothetical protein 317180..317260 Helicobacter pylori Shi470 6296770 YP_001909809.1 CDS HPSH_01645 NC_010698.2 317346 318101 R COG0748 Putative heme iron utilization protein; hypothetical protein complement(317346..318101) Helicobacter pylori Shi470 6296347 YP_001909810.1 CDS argS NC_010698.2 318162 319787 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(318162..319787) Helicobacter pylori Shi470 6296771 YP_001909811.1 CDS HPSH_01655 NC_010698.2 319790 320029 R COG1826 Sec-independent protein secretion pathway components; sec-independent protein translocase protein complement(319790..320029) Helicobacter pylori Shi470 6296080 YP_001909812.1 CDS gmk NC_010698.2 320099 320719 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(320099..320719) Helicobacter pylori Shi470 6296426 YP_001909813.1 CDS HPSH_01665 NC_010698.2 320712 322187 R poly E-rich protein complement(320712..322187) Helicobacter pylori Shi470 6297351 YP_001909814.1 CDS HPSH_01670 NC_010698.2 322200 322325 R hypothetical protein complement(322200..322325) Helicobacter pylori Shi470 6296489 YP_001909815.1 CDS HPSH_01675 NC_010698.2 322329 322871 D membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT 322329..322871 Helicobacter pylori Shi470 6297375 YP_001909816.1 CDS HPSH_01680 NC_010698.2 322878 323615 R outer membrane protein HorC complement(322878..323615) Helicobacter pylori Shi470 6296505 YP_001909817.1 CDS flgH NC_010698.2 323745 324458 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 323745..324458 Helicobacter pylori Shi470 6296650 YP_001909818.1 CDS HPSH_01690 NC_010698.2 324476 325159 D COG1083 CMP-N-acetylneuraminic acid synthetase; CMP-N-acetylneuraminic acid synthetase 324476..325159 Helicobacter pylori Shi470 6296388 YP_001909819.1 CDS HPSH_01695 NC_010698.2 325150 326022 D COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase; CMP-N-acetylneuraminic acid synthetase NeuA 325150..326022 Helicobacter pylori Shi470 6296210 YP_001909820.1 CDS HPSH_01700 NC_010698.2 326019 326561 D COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; flagellar biosynthesis protein G 326019..326561 Helicobacter pylori Shi470 6296409 YP_001909821.1 CDS lpxK NC_010698.2 326494 327432 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(326494..327432) Helicobacter pylori Shi470 6296250 YP_001909822.1 CDS HPSH_01710 NC_010698.2 327429 328211 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(327429..328211) Helicobacter pylori Shi470 6296428 YP_001909823.1 CDS HPSH_01715 NC_010698.2 328458 329450 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 328458..329450 Helicobacter pylori Shi470 6296305 YP_001909824.1 CDS HPSH_01720 NC_010698.2 329469 330275 D COG2894 Septum formation inhibitor-activating ATPase; cell division inhibitor MinD 329469..330275 Helicobacter pylori Shi470 6297345 YP_001909825.1 CDS minE NC_010698.2 330272 330505 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 330272..330505 Helicobacter pylori Shi470 6296055 YP_001909826.1 CDS HPSH_01730 NC_010698.2 330517 331317 D COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 330517..331317 Helicobacter pylori Shi470 6296194 YP_001909827.1 CDS HPSH_01735 NC_010698.2 331314 331718 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 331314..331718 Helicobacter pylori Shi470 6296225 YP_001909828.1 CDS HPSH_01740 NC_010698.2 331775 331849 D hypothetical protein 331775..331849 Helicobacter pylori Shi470 6297332 YP_001909829.1 CDS HPSH_01745 NC_010698.2 331849 332319 D COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein H 331849..332319 Helicobacter pylori Shi470 6296536 YP_001909830.1 CDS HPSH_01750 NC_010698.2 332509 332847 D hypothetical protein 332509..332847 Helicobacter pylori Shi470 6297316 YP_001909831.1 CDS HPSH_01755 NC_010698.2 332831 333397 D hypothetical protein 332831..333397 Helicobacter pylori Shi470 6296923 YP_001909832.1 CDS HPSH_01760 NC_010698.2 333409 333657 D hypothetical protein 333409..333657 Helicobacter pylori Shi470 6297100 YP_001909833.1 CDS HPSH_01765 NC_010698.2 333663 334040 D hypothetical protein 333663..334040 Helicobacter pylori Shi470 6297274 YP_001909834.1 CDS HPSH_01770 NC_010698.2 334131 334250 D hypothetical protein 334131..334250 Helicobacter pylori Shi470 6296112 YP_001909835.1 CDS HPSH_01775 NC_010698.2 334247 334321 D hypothetical protein 334247..334321 Helicobacter pylori Shi470 6296282 YP_001909836.1 CDS HPSH_01780 NC_010698.2 334312 334773 D COG3326 Predicted membrane protein; hypothetical protein 334312..334773 Helicobacter pylori Shi470 6296944 YP_001909837.1 CDS HPSH_01785 NC_010698.2 334789 335574 D hypothetical protein 334789..335574 Helicobacter pylori Shi470 6296345 YP_001909838.1 CDS HPSH_01790 NC_010698.2 335564 336646 D hypothetical protein 335564..336646 Helicobacter pylori Shi470 6296283 YP_001909839.1 CDS HPSH_01795 NC_010698.2 336702 337583 R COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein complement(336702..337583) Helicobacter pylori Shi470 6296006 YP_001909840.1 CDS HPSH_01800 NC_010698.2 337583 339133 R COG0608 Single-stranded DNA-specific exonuclease; single-stranded-DNA specific exonuclease complement(337583..339133) Helicobacter pylori Shi470 6296254 YP_001909841.1 CDS pyrG NC_010698.2 339142 340758 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(339142..340758) Helicobacter pylori Shi470 6296220 YP_001909842.1 CDS HPSH_01810 NC_010698.2 341014 341676 D COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 341014..341676 Helicobacter pylori Shi470 6296494 YP_001909843.1 CDS fliF NC_010698.2 341720 343423 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 341720..343423 Helicobacter pylori Shi470 6296045 YP_001909844.1 CDS fliG NC_010698.2 343442 344473 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 343442..344473 Helicobacter pylori Shi470 6296100 YP_001909845.1 CDS fliH NC_010698.2 344466 345236 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 344466..345236 Helicobacter pylori Shi470 6296186 YP_001909846.1 CDS HPSH_01830 NC_010698.2 345239 347089 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 345239..347089 Helicobacter pylori Shi470 6296159 YP_001909847.1 CDS HPSH_01835 NC_010698.2 347086 348894 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 347086..348894 Helicobacter pylori Shi470 6296204 YP_001909848.1 CDS HPSH_01840 NC_010698.2 348903 349832 D COG0270 Site-specific DNA methylase; DNA-cytosine methyltransferase 348903..349832 Helicobacter pylori Shi470 6297439 YP_001909849.1 CDS HPSH_01845 NC_010698.2 349825 350295 D hypothetical protein 349825..350295 Helicobacter pylori Shi470 6296197 YP_001909850.1 CDS HPSH_01850 NC_010698.2 350770 351579 R COG4786 Flagellar basal body rod protein; flagellar basal-body rod protein FlgG complement(350770..351579) Helicobacter pylori Shi470 6297254 YP_001909851.1 CDS HPSH_01855 NC_010698.2 351634 352920 R COG0477 Permeases of the major facilitator superfamily; alpha-ketoglutarate permease complement(351634..352920) Helicobacter pylori Shi470 6296931 YP_001909852.1 CDS HPSH_01860 NC_010698.2 353083 355722 R COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division protein complement(353083..355722) Helicobacter pylori Shi470 6297184 YP_001909853.1 CDS HPSH_01865 NC_010698.2 355719 358055 R COG3893 Inactivated superfamily I helicase; hypothetical protein complement(355719..358055) Helicobacter pylori Shi470 6296077 YP_001909854.1 CDS HPSH_01870 NC_010698.2 358052 359977 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(358052..359977) Helicobacter pylori Shi470 6296067 YP_001909855.1 CDS HPSH_01875 NC_010698.2 360024 360866 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(360024..360866) Helicobacter pylori Shi470 6297277 YP_001909856.1 CDS HPSH_01880 NC_010698.2 360832 361539 R COG1189 Predicted rRNA methylase; hemolysin complement(360832..361539) Helicobacter pylori Shi470 6296023 YP_001909857.1 CDS HPSH_01885 NC_010698.2 361539 362048 R hypothetical protein complement(361539..362048) Helicobacter pylori Shi470 6296286 YP_001909858.1 CDS pyrB NC_010698.2 362121 363044 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 362121..363044 Helicobacter pylori Shi470 6296457 YP_001909859.1 CDS HPSH_01895 NC_010698.2 363054 363134 R hypothetical protein complement(363054..363134) Helicobacter pylori Shi470 6297297 YP_001909860.1 CDS HPSH_01900 NC_010698.2 363339 364778 D hypothetical protein 363339..364778 Helicobacter pylori Shi470 6296855 YP_001909861.1 CDS HPSH_01905 NC_010698.2 364870 366525 D COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein MsbA 364870..366525 Helicobacter pylori Shi470 6296013 YP_001909862.1 CDS HPSH_01910 NC_010698.2 366519 367142 D hypothetical protein 366519..367142 Helicobacter pylori Shi470 6296140 YP_001909863.1 CDS HPSH_01915 NC_010698.2 367146 367715 D COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes; hypothetical protein 367146..367715 Helicobacter pylori Shi470 6297206 YP_001909864.1 CDS HPSH_01920 NC_010698.2 367826 369016 D COG1106 Predicted ATPases; hypothetical protein 367826..369016 Helicobacter pylori Shi470 6296135 YP_001909865.1 CDS HPSH_01925 NC_010698.2 369009 369671 D hypothetical protein 369009..369671 Helicobacter pylori Shi470 6297028 YP_001909866.1 CDS HPSH_01930 NC_010698.2 369752 370741 D COG3376 High-affinity nickel permease; high affinity nickel transport protein 369752..370741 Helicobacter pylori Shi470 6296474 YP_001909867.1 CDS HPSH_01935 NC_010698.2 370745 371260 R hypothetical protein complement(370745..371260) Helicobacter pylori Shi470 6296026 YP_001909868.1 CDS HPSH_01940 NC_010698.2 371393 372709 D hypothetical protein 371393..372709 Helicobacter pylori Shi470 6296219 YP_001909869.1 CDS HPSH_01945 NC_010698.2 373057 373194 D hypothetical protein 373057..373194 Helicobacter pylori Shi470 6296114 YP_001909870.1 CDS HPSH_01950 NC_010698.2 373184 373249 D hypothetical protein 373184..373249 Helicobacter pylori Shi470 6297339 YP_001909871.1 CDS HPSH_01955 NC_010698.2 373334 373462 D hypothetical protein 373334..373462 Helicobacter pylori Shi470 6296497 YP_001909872.1 CDS HPSH_01960 NC_010698.2 373835 374038 R COG2608 Copper chaperone; copper ion binding protein CopP complement(373835..374038) Helicobacter pylori Shi470 6296366 YP_001909873.1 CDS HPSH_01965 NC_010698.2 374039 376264 R COG2217 Cation transport ATPase; copper-transporting ATPase complement(374039..376264) Helicobacter pylori Shi470 6296149 YP_001909874.1 CDS HPSH_01970 NC_010698.2 376261 376974 R COG1183 Phosphatidylserine synthase; phosphatidylserine synthase complement(376261..376974) Helicobacter pylori Shi470 6296276 YP_001909875.1 CDS HPSH_01975 NC_010698.2 377220 379118 R COG0465 ATP-dependent Zn proteases; cell division protein FtsH complement(377220..379118) Helicobacter pylori Shi470 6296110 YP_001909876.1 CDS prmA NC_010698.2 379127 380116 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase complement(379127..380116) Helicobacter pylori Shi470 6296162 YP_001909877.1 CDS HPSH_01985 NC_010698.2 380117 380491 R COG0784 FOG: CheY-like receiver; response regulator complement(380117..380491) Helicobacter pylori Shi470 6296205 YP_001909878.1 CDS HPSH_01990 NC_010698.2 380783 381385 D outer membrane protein HorD 380783..381385 Helicobacter pylori Shi470 6296446 YP_001909879.1 CDS HPSH_01995 NC_010698.2 381517 381924 R hypothetical protein complement(381517..381924) Helicobacter pylori Shi470 6296478 YP_001909880.1 CDS HPSH_02000 NC_010698.2 381927 382157 R hypothetical protein complement(381927..382157) Helicobacter pylori Shi470 6296048 YP_001909881.1 CDS gidB NC_010698.2 382151 382687 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(382151..382687) Helicobacter pylori Shi470 6296437 YP_001909882.1 CDS queA NC_010698.2 382684 383721 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(382684..383721) Helicobacter pylori Shi470 6296176 YP_001909883.1 CDS HPSH_02015 NC_010698.2 383722 384483 R COG0805 Sec-independent protein secretion pathway component TatC; hypothetical protein complement(383722..384483) Helicobacter pylori Shi470 6297140 YP_001909884.1 CDS HPSH_02020 NC_010698.2 384476 384958 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(384476..384958) Helicobacter pylori Shi470 6296917 YP_001909885.1 CDS ruvB NC_010698.2 385026 386036 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(385026..386036) Helicobacter pylori Shi470 6296241 YP_001909886.1 CDS panB NC_010698.2 386037 386849 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(386037..386849) Helicobacter pylori Shi470 6296500 YP_001909887.1 CDS HPSH_02035 NC_010698.2 386997 387719 D hypothetical protein 386997..387719 Helicobacter pylori Shi470 6296198 YP_001909888.1 CDS HPSH_02040 NC_010698.2 387709 388563 D hypothetical protein 387709..388563 Helicobacter pylori Shi470 6296299 YP_001909889.1 CDS HPSH_02045 NC_010698.2 388575 389516 D hypothetical protein 388575..389516 Helicobacter pylori Shi470 6296233 YP_001909890.1 CDS HPSH_02050 NC_010698.2 389526 390848 D COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 389526..390848 Helicobacter pylori Shi470 6296022 YP_001909891.1 CDS minC NC_010698.2 390851 391438 D blocks the formation of polar Z-ring septums; septum formation inhibitor 390851..391438 Helicobacter pylori Shi470 6296865 YP_001909892.1 CDS lpxC NC_010698.2 391435 392322 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 391435..392322 Helicobacter pylori Shi470 6295992 YP_001909893.1 CDS HPSH_02065 NC_010698.2 392343 392816 D COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; hypothetical protein 392343..392816 Helicobacter pylori Shi470 6296307 YP_001909894.1 CDS HPSH_02070 NC_010698.2 392871 393752 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 392871..393752 Helicobacter pylori Shi470 6295993 YP_001909895.1 CDS HPSH_02075 NC_010698.2 393739 393993 D COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; hypothetical protein 393739..393993 Helicobacter pylori Shi470 6297242 YP_001909896.1 CDS infB NC_010698.2 393990 396836 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 393990..396836 Helicobacter pylori Shi470 6296230 YP_001909897.1 CDS rbfA NC_010698.2 396836 397171 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 396836..397171 Helicobacter pylori Shi470 6296498 YP_001909898.1 CDS HPSH_02090 NC_010698.2 397164 397604 D COG0779 Uncharacterized protein conserved in bacteria; hypothetical protein 397164..397604 Helicobacter pylori Shi470 6297264 YP_001909899.1 CDS HPSH_02095 NC_010698.2 397774 398886 D COG1408 Predicted phosphohydrolases; hypothetical protein 397774..398886 Helicobacter pylori Shi470 6296293 YP_001909900.1 CDS HPSH_02100 NC_010698.2 399227 399898 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative transcriptional regulator 399227..399898 Helicobacter pylori Shi470 6296310 YP_001909901.1 CDS HPSH_02105 NC_010698.2 400230 401276 R COG2404 Predicted phosphohydrolase (DHH superfamily); hypothetical protein complement(400230..401276) Helicobacter pylori Shi470 6296020 YP_001909902.1 CDS flhA NC_010698.2 401304 403505 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(401304..403505) Helicobacter pylori Shi470 6296424 YP_001909903.1 CDS rpsO NC_010698.2 403643 403915 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 403643..403915 Helicobacter pylori Shi470 6296302 YP_001909904.1 CDS HPSH_02120 NC_010698.2 403945 405234 D COG3307 Lipid A core - O-antigen ligase and related enzymes; hypothetical protein 403945..405234 Helicobacter pylori Shi470 6296214 YP_001909905.1 CDS HPSH_02125 NC_010698.2 405363 405866 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 405363..405866 Helicobacter pylori Shi470 6297164 YP_001909906.1 CDS HPSH_02130 NC_010698.2 405880 406953 D COG0006 Xaa-Pro aminopeptidase; hypothetical protein 405880..406953 Helicobacter pylori Shi470 6296146 YP_001909907.1 CDS HPSH_02135 NC_010698.2 406953 407441 D COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase FolK 406953..407441 Helicobacter pylori Shi470 6296969 YP_001909908.1 CDS flhF NC_010698.2 407435 408814 D positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 407435..408814 Helicobacter pylori Shi470 6296065 YP_001909909.1 CDS HPSH_02145 NC_010698.2 408811 409695 D COG0455 ATPases involved in chromosome partitioning; ATP-binding protein 408811..409695 Helicobacter pylori Shi470 6296525 YP_001909910.1 CDS HPSH_02150 NC_010698.2 409700 410014 D hypothetical protein 409700..410014 Helicobacter pylori Shi470 6297086 YP_001909911.1 CDS fliA NC_010698.2 410016 410768 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 410016..410768 Helicobacter pylori Shi470 6296129 YP_001909912.1 CDS fliM NC_010698.2 410761 411825 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 410761..411825 Helicobacter pylori Shi470 6297087 YP_001909913.1 CDS HPSH_02165 NC_010698.2 411829 412695 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY 411829..412695 Helicobacter pylori Shi470 6296295 YP_001909914.1 CDS HPSH_02170 NC_010698.2 412724 413260 D COG2731 Beta-galactosidase, beta subunit; hypothetical protein 412724..413260 Helicobacter pylori Shi470 6295996 YP_001909915.1 CDS HPSH_02175 NC_010698.2 413257 413757 D COG4731 Uncharacterized protein conserved in bacteria; hypothetical protein 413257..413757 Helicobacter pylori Shi470 6296499 YP_001909916.1 CDS HPSH_02180 NC_010698.2 413777 414229 R COG0735 Fe2+/Zn2+ uptake regulation proteins; ferric uptake regulation protein complement(413777..414229) Helicobacter pylori Shi470 6296971 YP_001909917.1 CDS HPSH_02185 NC_010698.2 414389 415564 R COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA complement(414389..415564) Helicobacter pylori Shi470 6296209 YP_001909918.1 CDS HPSH_02190 NC_010698.2 415561 415932 R COG0789 Predicted transcriptional regulators; putative heat shock protein HspR complement(415561..415932) Helicobacter pylori Shi470 6296935 YP_001909919.1 CDS HPSH_02195 NC_010698.2 415942 416808 R COG2214 DnaJ-class molecular chaperone; co-chaperone-curved DNA binding protein A complement(415942..416808) Helicobacter pylori Shi470 6296421 YP_001909920.1 CDS HPSH_02200 NC_010698.2 416976 418226 D hypothetical protein 416976..418226 Helicobacter pylori Shi470 6296455 YP_001909921.1 CDS HPSH_02205 NC_010698.2 418248 419024 R COG0258 5'-3' exonuclease (including N-terminal domain of PolI); hypothetical protein complement(418248..419024) Helicobacter pylori Shi470 6296012 YP_001909922.1 CDS HPSH_02210 NC_010698.2 419350 420246 R COG0784 FOG: CheY-like receiver; response regulator complement(419350..420246) Helicobacter pylori Shi470 6296165 YP_001909923.1 CDS ispDF NC_010698.2 420278 421498 R bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein complement(420278..421498) Helicobacter pylori Shi470 6296321 YP_001909924.1 CDS HPSH_02220 NC_010698.2 421520 422950 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; protease DO complement(421520..422950) Helicobacter pylori Shi470 6296506 YP_001909925.1 CDS HPSH_02225 NC_010698.2 422995 424437 R COG0833 Amino acid transporters; amino acid permease complement(422995..424437) Helicobacter pylori Shi470 6296044 YP_001909926.1 CDS HPSH_02230 NC_010698.2 424632 425171 R COG0558 Phosphatidylglycerophosphate synthase; phosphatidylglycerophosphate synthase complement(424632..425171) Helicobacter pylori Shi470 6296843 YP_001909927.1 CDS HPSH_02235 NC_010698.2 425168 425776 R hypothetical protein complement(425168..425776) Helicobacter pylori Shi470 6296440 YP_001909928.1 CDS HPSH_02240 NC_010698.2 425786 426574 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(425786..426574) Helicobacter pylori Shi470 6296845 YP_001909929.1 CDS HPSH_02245 NC_010698.2 426571 427473 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(426571..427473) Helicobacter pylori Shi470 6296493 YP_001909930.1 CDS HPSH_02250 NC_010698.2 427488 428822 R COG0612 Predicted Zn-dependent peptidases; putative zinc protease complement(427488..428822) Helicobacter pylori Shi470 6297271 YP_001909931.1 CDS HPSH_02255 NC_010698.2 428819 429874 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(428819..429874) Helicobacter pylori Shi470 6296003 YP_001909932.1 CDS HPSH_02260 NC_010698.2 429911 431938 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(429911..431938) Helicobacter pylori Shi470 6296142 YP_001909933.1 CDS HPSH_02265 NC_010698.2 432577 433692 R COG0732 Restriction endonuclease S subunits; hypothetical protein complement(432577..433692) Helicobacter pylori Shi470 6297068 YP_001909934.1 CDS HPSH_02270 NC_010698.2 433685 435316 R COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme M protein complement(433685..435316) Helicobacter pylori Shi470 6296509 YP_001909935.1 CDS HPSH_02275 NC_010698.2 435309 438410 R COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme R protein HsdR complement(435309..438410) Helicobacter pylori Shi470 6297155 YP_001909936.1 CDS HPSH_02280 NC_010698.2 438458 440353 R COG2604 Uncharacterized protein conserved in bacteria; hypothetical protein complement(438458..440353) Helicobacter pylori Shi470 6296074 YP_001909937.1 CDS HPSH_02285 NC_010698.2 440379 441146 R hypothetical protein complement(440379..441146) Helicobacter pylori Shi470 6296568 YP_001909938.1 CDS HPSH_02290 NC_010698.2 441156 441470 R hypothetical protein complement(441156..441470) Helicobacter pylori Shi470 6296532 YP_001909939.1 CDS HPSH_02295 NC_010698.2 441472 442959 R COG2048 Heterodisulfide reductase, subunit B; hypothetical protein complement(441472..442959) Helicobacter pylori Shi470 6296469 YP_001909940.1 CDS HPSH_02300 NC_010698.2 442971 443459 R hypothetical protein complement(442971..443459) Helicobacter pylori Shi470 6296444 YP_001909941.1 CDS HPSH_02305 NC_010698.2 443444 445180 R COG1164 Oligoendopeptidase F; oligoendopeptidase F PepF complement(443444..445180) Helicobacter pylori Shi470 6296237 YP_001909942.1 CDS HPSH_02310 NC_010698.2 445277 446527 R COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefB complement(445277..446527) Helicobacter pylori Shi470 6296260 YP_001909943.1 CDS HPSH_02315 NC_010698.2 446680 446871 R hypothetical protein complement(446680..446871) Helicobacter pylori Shi470 6296090 YP_001909944.1 CDS HPSH_02320 NC_010698.2 446855 447415 R outer membrane protein complement(446855..447415) Helicobacter pylori Shi470 6297370 YP_001909945.1 CDS HPSH_02325 NC_010698.2 447459 447611 R hypothetical protein complement(447459..447611) Helicobacter pylori Shi470 6296043 YP_001909946.1 CDS HPSH_02330 NC_010698.2 447639 448379 D COG0725 ABC-type molybdate transport system, periplasmic component; molybdenum ABC transporter ModA 447639..448379 Helicobacter pylori Shi470 6296485 YP_001909947.1 CDS HPSH_02335 NC_010698.2 448401 449075 D COG4149 ABC-type molybdate transport system, permease component; molybdenum ABC transporter ModB 448401..449075 Helicobacter pylori Shi470 6297236 YP_001909948.1 CDS HPSH_02340 NC_010698.2 449072 449869 D COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; molybdenum ABC transporter ModD 449072..449869 Helicobacter pylori Shi470 6296117 YP_001909949.1 CDS gltX NC_010698.2 449951 451342 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(449951..451342) Helicobacter pylori Shi470 6296962 YP_001909950.1 CDS HPSH_02350 NC_010698.2 451461 452564 D outer membrane protein 451461..452564 Helicobacter pylori Shi470 6297216 YP_001909951.1 CDS HPSH_02355 NC_010698.2 452573 455023 D COG0286 Type I restriction-modification system methyltransferase subunit; type II adenine specific methyltransferase 452573..455023 Helicobacter pylori Shi470 6296119 YP_001909952.1 CDS HPSH_02360 NC_010698.2 455069 456868 D COG1217 Predicted membrane GTPase involved in stress response; hypothetical protein 455069..456868 Helicobacter pylori Shi470 6296108 YP_001909953.1 CDS HPSH_02365 NC_010698.2 456884 457813 D COG0338 Site-specific DNA methylase; type II adenine specific DNA methyltransferase 456884..457813 Helicobacter pylori Shi470 6296454 YP_001909954.1 CDS HPSH_02370 NC_010698.2 457816 458439 D type II restriction endonuclease 457816..458439 Helicobacter pylori Shi470 6296070 YP_001909955.1 CDS HPSH_02375 NC_010698.2 458530 459576 D COG0270 Site-specific DNA methylase; type II DNA modification methyltransferase 458530..459576 Helicobacter pylori Shi470 6296502 YP_001909956.1 CDS HPSH_02380 NC_010698.2 459579 459842 D hypothetical protein 459579..459842 Helicobacter pylori Shi470 6296124 YP_001909957.1 CDS HPSH_02385 NC_010698.2 459889 460326 D hypothetical protein 459889..460326 Helicobacter pylori Shi470 6296508 YP_001909958.1 CDS HPSH_02390 NC_010698.2 460342 460509 R hypothetical protein complement(460342..460509) Helicobacter pylori Shi470 6296482 YP_001909959.1 CDS HPSH_02395 NC_010698.2 460559 461503 R COG0753 Catalase; catalase-like protein complement(460559..461503) Helicobacter pylori Shi470 6297308 YP_001909960.1 CDS HPSH_02400 NC_010698.2 461787 463373 D outer membrane protein HofC 461787..463373 Helicobacter pylori Shi470 6296157 YP_001909961.1 CDS HPSH_02405 NC_010698.2 463443 464840 D putative Outer membrane protein 463443..464840 Helicobacter pylori Shi470 6296334 YP_001909962.1 CDS HPSH_02410 NC_010698.2 465292 465498 R hypothetical protein complement(465292..465498) Helicobacter pylori Shi470 6296061 YP_001909963.1 CDS HPSH_02415 NC_010698.2 465596 466195 D hypothetical protein 465596..466195 Helicobacter pylori Shi470 6296007 YP_001909964.1 CDS HPSH_02420 NC_010698.2 466552 467277 R COG1432 Uncharacterized conserved protein; hypothetical protein complement(466552..467277) Helicobacter pylori Shi470 6297088 YP_001909965.1 CDS ruvC NC_010698.2 467410 467883 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 467410..467883 Helicobacter pylori Shi470 6296551 YP_001909966.1 CDS HPSH_02430 NC_010698.2 467884 470259 R COG1629 Outer membrane receptor proteins, mostly Fe transport; iron-regulated outer membrane protein FrpB complement(467884..470259) Helicobacter pylori Shi470 6296410 YP_001909967.1 CDS HPSH_02435 NC_010698.2 470584 472110 D COG0753 Catalase; catalase 470584..472110 Helicobacter pylori Shi470 6297260 YP_001909968.1 CDS HPSH_02440 NC_010698.2 472261 473136 D hypothetical protein 472261..473136 Helicobacter pylori Shi470 6296094 YP_001909969.1 CDS HPSH_02445 NC_010698.2 473217 473432 D hypothetical protein 473217..473432 Helicobacter pylori Shi470 6296151 YP_001909970.1 CDS HPSH_02450 NC_010698.2 473490 473819 R COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; alkylphosphonate uptake protein complement(473490..473819) Helicobacter pylori Shi470 6296395 YP_001909971.1 CDS HPSH_02455 NC_010698.2 474171 474905 D COG2134 CDP-diacylglycerol pyrophosphatase; CDP-diacylglycerol pyrophosphatase 474171..474905 Helicobacter pylori Shi470 6296468 YP_001909972.1 CDS flgE NC_010698.2 475109 477265 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 475109..477265 Helicobacter pylori Shi470 6296322 YP_001909973.1 CDS hypA NC_010698.2 477323 477676 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 477323..477676 Helicobacter pylori Shi470 6297149 YP_001909974.1 CDS HPSH_02470 NC_010698.2 477683 478144 D hypothetical protein 477683..478144 Helicobacter pylori Shi470 6296435 YP_001909975.1 CDS lpxB NC_010698.2 478144 479226 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase 478144..479226 Helicobacter pylori Shi470 6297083 YP_001909976.1 CDS greA NC_010698.2 479267 479761 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 479267..479761 Helicobacter pylori Shi470 6296519 YP_001909977.1 CDS dut NC_010698.2 479751 480188 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 479751..480188 Helicobacter pylori Shi470 6296438 YP_001909978.1 CDS HPSH_02490 NC_010698.2 480185 480841 D hypothetical protein 480185..480841 Helicobacter pylori Shi470 6296361 YP_001909979.1 CDS HPSH_02495 NC_010698.2 480846 482540 D hypothetical protein 480846..482540 Helicobacter pylori Shi470 6296471 YP_001909980.1 CDS HPSH_02500 NC_010698.2 482545 483216 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 482545..483216 Helicobacter pylori Shi470 6297230 YP_001909981.1 CDS HPSH_02505 NC_010698.2 483207 483944 D COG2836 Uncharacterized conserved protein; hypothetical protein 483207..483944 Helicobacter pylori Shi470 6297163 YP_001909982.1 CDS HPSH_02510 NC_010698.2 483931 484455 D COG0241 Histidinol phosphatase and related phosphatases; hypothetical protein 483931..484455 Helicobacter pylori Shi470 6296529 YP_001909983.1 CDS HPSH_02515 NC_010698.2 484464 485456 D COG0451 Nucleoside-diphosphate-sugar epimerases; ADP-L-glycero-D-mannoheptose-6-epimerase RfaD 484464..485456 Helicobacter pylori Shi470 6297263 YP_001909984.1 CDS HPSH_02520 NC_010698.2 485453 486844 D COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; ADP-heptose synthase 485453..486844 Helicobacter pylori Shi470 6296123 YP_001909985.1 CDS HPSH_02525 NC_010698.2 486837 487415 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 486837..487415 Helicobacter pylori Shi470 6296378 YP_001909986.1 CDS HPSH_02530 NC_010698.2 487592 488569 R COG0516 IMP dehydrogenase/GMP reductase; guanosine 5'-monophosphate oxidoreductase complement(487592..488569) Helicobacter pylori Shi470 6296520 YP_001909987.1 CDS HPSH_02535 NC_010698.2 488818 490419 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 488818..490419 Helicobacter pylori Shi470 6296245 YP_001909988.1 CDS HPSH_02540 NC_010698.2 490416 491333 D COG2958 Uncharacterized protein conserved in bacteria; hypothetical protein 490416..491333 Helicobacter pylori Shi470 6295997 YP_001909989.1 CDS HPSH_02545 NC_010698.2 491371 492048 R COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein complement(491371..492048) Helicobacter pylori Shi470 6297124 YP_001909990.1 CDS HPSH_02550 NC_010698.2 492215 493168 R type II restriction endonuclease complement(492215..493168) Helicobacter pylori Shi470 6296417 YP_001909991.1 CDS HPSH_02555 NC_010698.2 493165 494148 R COG0270 Site-specific DNA methylase; site-specific DNA methyltransferase complement(493165..494148) Helicobacter pylori Shi470 6296441 YP_001909992.1 CDS HPSH_02560 NC_010698.2 494332 495921 D COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme M protein HsdM 494332..495921 Helicobacter pylori Shi470 6296001 YP_001909993.1 CDS HPSH_02565 NC_010698.2 495914 497182 D COG0732 Restriction endonuclease S subunits; anti-codon nuclease masking agent PrrB 495914..497182 Helicobacter pylori Shi470 6296042 YP_001909994.1 CDS HPSH_02570 NC_010698.2 497186 500185 D COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme R protein 497186..500185 Helicobacter pylori Shi470 6297384 YP_001909995.1 CDS HPSH_02575 NC_010698.2 500272 501051 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 500272..501051 Helicobacter pylori Shi470 6296306 YP_001909996.1 CDS HPSH_02580 NC_010698.2 501048 501857 D COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; thiamine biosynthesis protein (thi) 501048..501857 Helicobacter pylori Shi470 6296172 YP_001909997.1 CDS thiE NC_010698.2 501850 502509 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 501850..502509 Helicobacter pylori Shi470 6296133 YP_001909998.1 CDS HPSH_02590 NC_010698.2 502564 503301 R hypothetical protein complement(502564..503301) Helicobacter pylori Shi470 6296535 YP_001909999.1 CDS HPSH_02595 NC_010698.2 503301 504578 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(503301..504578) Helicobacter pylori Shi470 6296263 YP_001910000.1 CDS HPSH_02600 NC_010698.2 504575 505558 R COG1086 Predicted nucleoside-diphosphate sugar epimerases; UDP-GlcNAc C6 dehydratase complement(504575..505558) Helicobacter pylori Shi470 6296148 YP_001910001.1 CDS HPSH_02605 NC_010698.2 505562 507325 R COG2067 Long-chain fatty acid transport protein; outer membrane protein P1 complement(505562..507325) Helicobacter pylori Shi470 6296333 YP_001910002.1 CDS HPSH_02610 NC_010698.2 507322 507939 R hypothetical protein complement(507322..507939) Helicobacter pylori Shi470 6296304 YP_001910003.1 CDS HPSH_02615 NC_010698.2 507958 508563 R COG3018 Uncharacterized protein conserved in bacteria; hypothetical protein complement(507958..508563) Helicobacter pylori Shi470 6296190 YP_001910004.1 CDS HPSH_02620 NC_010698.2 508903 509007 R hypothetical protein complement(508903..509007) Helicobacter pylori Shi470 6296540 YP_001910005.1 CDS HPSH_02625 NC_010698.2 509236 509520 R COG0776 Bacterial nucleoid DNA-binding protein; dna-binding protein hu complement(509236..509520) Helicobacter pylori Shi470 6296262 YP_001910006.1 CDS engA NC_010698.2 509662 511047 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(509662..511047) Helicobacter pylori Shi470 6296121 YP_001910007.1 CDS HPSH_02635 NC_010698.2 511124 512008 D hypothetical protein 511124..512008 Helicobacter pylori Shi470 6296379 YP_001910008.1 CDS speE NC_010698.2 512093 512881 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 512093..512881 Helicobacter pylori Shi470 6297071 YP_001910009.1 CDS coaE NC_010698.2 512883 513473 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 512883..513473 Helicobacter pylori Shi470 6296383 YP_001910010.1 CDS gatA NC_010698.2 513532 514893 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 513532..514893 Helicobacter pylori Shi470 6296192 YP_001910011.1 CDS HPSH_02655 NC_010698.2 514903 516348 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 514903..516348 Helicobacter pylori Shi470 6296264 YP_001910012.1 CDS HPSH_02660 NC_010698.2 516470 517150 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 516470..517150 Helicobacter pylori Shi470 6296134 YP_001910013.1 CDS HPSH_02665 NC_010698.2 517147 517242 R hypothetical protein complement(517147..517242) Helicobacter pylori Shi470 6296126 YP_001910014.1 CDS HPSH_02670 NC_010698.2 517470 517718 D COG0724 RNA-binding proteins (RRM domain); RNA binding protein 517470..517718 Helicobacter pylori Shi470 6297037 YP_001910015.1 CDS HPSH_02675 NC_010698.2 517921 518742 R COG3306 Glycosyltransferase involved in LPS biosynthesis; lipooligosaccharide 5G8 epitope biosynthesis-associated protein complement(517921..518742) Helicobacter pylori Shi470 6296052 YP_001910016.1 CDS HPSH_02680 NC_010698.2 518909 519844 R COG0492 Thioredoxin reductase; thioredoxin reductase complement(518909..519844) Helicobacter pylori Shi470 6296238 YP_001910017.1 CDS HPSH_02685 NC_010698.2 519850 520170 R COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin complement(519850..520170) Helicobacter pylori Shi470 6296252 YP_001910018.1 CDS HPSH_02690 NC_010698.2 520259 520603 R COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein complement(520259..520603) Helicobacter pylori Shi470 6296464 YP_001910019.1 CDS HPSH_02695 NC_010698.2 520604 521869 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(520604..521869) Helicobacter pylori Shi470 6297111 YP_001910020.1 CDS uvrC NC_010698.2 521880 523664 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(521880..523664) Helicobacter pylori Shi470 6296224 YP_001910021.1 CDS HPSH_02705 NC_010698.2 523665 524126 R hypothetical protein complement(523665..524126) Helicobacter pylori Shi470 6296419 YP_001910022.1 CDS HPSH_02710 NC_010698.2 524118 524297 D hypothetical protein 524118..524297 Helicobacter pylori Shi470 6296348 YP_001910023.1 CDS HPSH_02715 NC_010698.2 524309 524950 R COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; osmoprotection protein ProV complement(524309..524950) Helicobacter pylori Shi470 6296458 YP_001910024.1 CDS HPSH_02720 NC_010698.2 524952 526613 R COG1174 ABC-type proline/glycine betaine transport systems, permease component; osmoprotection protein ProWX complement(524952..526613) Helicobacter pylori Shi470 6296068 YP_001910025.1 CDS HPSH_02725 NC_010698.2 526793 527230 R hypothetical protein complement(526793..527230) Helicobacter pylori Shi470 6296496 YP_001910026.1 CDS motB NC_010698.2 527234 528001 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(527234..528001) Helicobacter pylori Shi470 6296846 YP_001910027.1 CDS HPSH_02735 NC_010698.2 528004 528777 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(528004..528777) Helicobacter pylori Shi470 6296177 YP_001910028.1 CDS HPSH_02740 NC_010698.2 528793 529560 R COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; thiamin biosynthesis protein ThiF complement(528793..529560) Helicobacter pylori Shi470 6296418 YP_001910029.1 CDS HPSH_02745 NC_010698.2 529561 530178 R COG0491 Zn-dependent hydrolases, including glyoxylases; hypothetical protein complement(529561..530178) Helicobacter pylori Shi470 6296512 YP_001910030.1 CDS HPSH_02750 NC_010698.2 530311 531321 D COG1565 Uncharacterized conserved protein; hypothetical protein 530311..531321 Helicobacter pylori Shi470 6296027 YP_001910031.1 CDS HPSH_02755 NC_010698.2 531511 531630 D hypothetical protein 531511..531630 Helicobacter pylori Shi470 6297057 YP_001910032.1 CDS HPSH_02760 NC_010698.2 531690 532082 D hypothetical protein 531690..532082 Helicobacter pylori Shi470 6296382 YP_001910033.1 CDS HPSH_02765 NC_010698.2 532124 532663 D COG0742 N6-adenine-specific methylase; N-6 adenine methyltransferase 532124..532663 Helicobacter pylori Shi470 6296396 YP_001910034.1 CDS fliL NC_010698.2 532672 533223 D interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 532672..533223 Helicobacter pylori Shi470 6297307 YP_001910035.1 CDS acpS NC_010698.2 533290 533586 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 533290..533586 Helicobacter pylori Shi470 6296337 YP_001910036.1 CDS HPSH_02780 NC_010698.2 533692 533826 D iron(III dicitrate transport protein FecA 533692..533826 Helicobacter pylori Shi470 6296248 YP_001910037.1 CDS HPSH_02785 NC_010698.2 533830 534450 R COG1451 Predicted metal-dependent hydrolase; hypothetical protein complement(533830..534450) Helicobacter pylori Shi470 6296103 YP_001910038.1 CDS HPSH_02790 NC_010698.2 534532 535368 D COG3306 Glycosyltransferase involved in LPS biosynthesis; putative lipopolysaccharide biosynthesis protein 534532..535368 Helicobacter pylori Shi470 6296024 YP_001910039.1 CDS HPSH_02795 NC_010698.2 535451 536485 D bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 535451..536485 Helicobacter pylori Shi470 6296034 YP_001910040.1 CDS HPSH_02800 NC_010698.2 536665 537411 D hypothetical protein 536665..537411 Helicobacter pylori Shi470 6296959 YP_001910041.1 CDS ribA NC_010698.2 537530 538108 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 537530..538108 Helicobacter pylori Shi470 6296004 YP_001910042.1 CDS HPSH_02810 NC_010698.2 538182 538403 D COG1977 Molybdopterin converting factor, small subunit; molybdopterin converting factor subunit 1 MoaD 538182..538403 Helicobacter pylori Shi470 6297117 YP_001910043.1 CDS HPSH_02815 NC_010698.2 538404 538841 D COG0314 Molybdopterin converting factor, large subunit; molybdopterin converting factor subunit 2 538404..538841 Helicobacter pylori Shi470 6296085 YP_001910044.1 CDS mogA NC_010698.2 538854 539384 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 538854..539384 Helicobacter pylori Shi470 6296956 YP_001910045.1 CDS moaC NC_010698.2 539393 539869 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 539393..539869 Helicobacter pylori Shi470 6296362 YP_001910046.1 CDS HPSH_02830 NC_010698.2 539988 540770 D flagellar sheath adhesin 539988..540770 Helicobacter pylori Shi470 6297081 YP_001910047.1 CDS HPSH_02835 NC_010698.2 540796 541632 D outer membrane protein 540796..541632 Helicobacter pylori Shi470 6296404 YP_001910048.1 CDS tig NC_010698.2 541745 543100 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 541745..543100 Helicobacter pylori Shi470 6296898 YP_001910049.1 CDS clpP NC_010698.2 543121 543708 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 543121..543708 Helicobacter pylori Shi470 6297355 YP_001910050.1 CDS def NC_010698.2 543713 544240 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 543713..544240 Helicobacter pylori Shi470 6296082 YP_001910051.1 CDS HPSH_02855 NC_010698.2 544243 545763 D COG0606 Predicted ATPase with chaperone activity; sigma-54 interacting protein 544243..545763 Helicobacter pylori Shi470 6296187 YP_001910052.1 CDS HPSH_02860 NC_010698.2 545788 547848 D COG2217 Cation transport ATPase; cadmium-transporting ATPase 545788..547848 Helicobacter pylori Shi470 6296166 YP_001910053.1 CDS HPSH_02865 NC_010698.2 547884 549158 D COG0732 Restriction endonuclease S subunits; anti-codon nuclease masking agent PrrB 547884..549158 Helicobacter pylori Shi470 6296174 YP_001910054.1 CDS HPSH_02870 NC_010698.2 549367 550866 R outer membrane protein HofF complement(549367..550866) Helicobacter pylori Shi470 6296215 YP_001910055.1 CDS HPSH_02875 NC_010698.2 551146 552432 R COG4591 ABC-type transport system, involved in lipoprotein release, permease component; lipoprotein release system transmembrane protein complement(551146..552432) Helicobacter pylori Shi470 6296332 YP_001910056.1 CDS HPSH_02880 NC_010698.2 552368 554965 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(552368..554965) Helicobacter pylori Shi470 6296168 YP_001910057.1 CDS lolA NC_010698.2 555085 555666 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 555085..555666 Helicobacter pylori Shi470 6296053 YP_001910058.1 CDS HPSH_02890 NC_010698.2 555691 555825 R hypothetical protein complement(555691..555825) Helicobacter pylori Shi470 6297030 YP_001910059.1 CDS HPSH_02895 NC_010698.2 556159 556686 D hypothetical protein 556159..556686 Helicobacter pylori Shi470 6296354 YP_001910060.1 CDS HPSH_02900 NC_010698.2 556693 558060 R hypothetical protein complement(556693..558060) Helicobacter pylori Shi470 6296392 YP_001910061.1 CDS HPSH_02905 NC_010698.2 558154 559443 R hypothetical protein complement(558154..559443) Helicobacter pylori Shi470 6296960 YP_001910062.1 CDS HPSH_02910 NC_010698.2 559843 559965 R hypothetical protein complement(559843..559965) Helicobacter pylori Shi470 6296895 YP_001910063.1 CDS HPSH_02915 NC_010698.2 560042 562600 R catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase complement(560042..562600) Helicobacter pylori Shi470 6296277 YP_001910064.1 CDS HPSH_02920 NC_010698.2 562731 563414 D COG1427 Predicted periplasmic solute-binding protein; hypothetical protein 562731..563414 Helicobacter pylori Shi470 6296271 YP_001910065.1 CDS pyrH NC_010698.2 563524 564246 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 563524..564246 Helicobacter pylori Shi470 6296069 YP_001910066.1 CDS HPSH_02930 NC_010698.2 564289 564513 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 564289..564513 Helicobacter pylori Shi470 6296528 YP_001910067.1 CDS HPSH_02935 NC_010698.2 564500 566830 D COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; penta-phosphate guanosine-3'-pyrophosphohydrolase SpoT 564500..566830 Helicobacter pylori Shi470 6296507 YP_001910068.1 CDS HPSH_02940 NC_010698.2 566851 568059 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 566851..568059 Helicobacter pylori Shi470 6296005 YP_001910069.1 CDS HPSH_02945 NC_010698.2 568070 569161 D COG2070 Dioxygenases related to 2-nitropropane dioxygenase; hypothetical protein 568070..569161 Helicobacter pylori Shi470 6296138 YP_001910070.1 CDS HPSH_02950 NC_010698.2 569168 570490 D COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 569168..570490 Helicobacter pylori Shi470 6297229 YP_001910071.1 CDS HPSH_02955 NC_010698.2 570509 571246 D hypothetical protein 570509..571246 Helicobacter pylori Shi470 6296284 YP_001910072.1 CDS HPSH_02970 NC_010698.2 572414 573019 R MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A complement(572414..573019) Helicobacter pylori Shi470 6296029 YP_001910073.1 CDS moaA NC_010698.2 573189 574070 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 573189..574070 Helicobacter pylori Shi470 6296057 YP_001910074.1 CDS HPSH_02980 NC_010698.2 574203 574412 R hypothetical protein complement(574203..574412) Helicobacter pylori Shi470 6296403 YP_001910075.1 CDS HPSH_02985 NC_010698.2 574311 574646 D hypothetical protein 574311..574646 Helicobacter pylori Shi470 6296071 YP_001910076.1 CDS HPSH_02990 NC_010698.2 574528 574854 D hypothetical protein 574528..574854 Helicobacter pylori Shi470 6296571 YP_001910077.1 CDS HPSH_02995 NC_010698.2 574871 575764 D COG1196 Chromosome segregation ATPases; hypothetical protein 574871..575764 Helicobacter pylori Shi470 6296327 YP_001910078.1 CDS HPSH_03000 NC_010698.2 575776 576630 D hypothetical protein 575776..576630 Helicobacter pylori Shi470 6297310 YP_001910079.1 CDS HPSH_03005 NC_010698.2 576670 577035 D COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 576670..577035 Helicobacter pylori Shi470 6297208 YP_001910080.1 CDS HPSH_03010 NC_010698.2 577044 577937 R COG0552 Signal recognition particle GTPase; cell division protein FtsY complement(577044..577937) Helicobacter pylori Shi470 6297312 YP_001910081.1 CDS HPSH_03015 NC_010698.2 577944 578501 R hypothetical protein complement(577944..578501) Helicobacter pylori Shi470 6296179 YP_001910082.1 CDS HPSH_03020 NC_010698.2 578626 579273 D COG0212 5-formyltetrahydrofolate cyclo-ligase; hypothetical protein 578626..579273 Helicobacter pylori Shi470 6296274 YP_001910083.1 CDS HPSH_03025 NC_010698.2 579251 580762 D protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 579251..580762 Helicobacter pylori Shi470 6296565 YP_001910084.1 CDS HPSH_03030 NC_010698.2 580763 582016 R COG0534 Na+-driven multidrug efflux pump; hypothetical protein complement(580763..582016) Helicobacter pylori Shi470 6296481 YP_001910085.1 CDS HPSH_03035 NC_010698.2 582079 583392 R COG2056 Predicted permease; hypothetical protein complement(582079..583392) Helicobacter pylori Shi470 6296285 YP_001910086.1 CDS HPSH_03040 NC_010698.2 583386 583469 R hypothetical protein complement(583386..583469) Helicobacter pylori Shi470 6296272 YP_001910087.1 CDS HPSH_03045 NC_010698.2 583519 584397 R COG0388 Predicted amidohydrolase; carbon-nitrogen hydrolase complement(583519..584397) Helicobacter pylori Shi470 6296109 YP_001910088.1 CDS HPSH_03050 NC_010698.2 584401 584547 R hypothetical protein complement(584401..584547) Helicobacter pylori Shi470 6296373 YP_001910089.1 CDS HPSH_03055 NC_010698.2 584576 585235 R COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; molybdopterin biosynthesis protein complement(584576..585235) Helicobacter pylori Shi470 6296451 YP_001910090.1 CDS HPSH_03060 NC_010698.2 585288 585527 R hypothetical protein complement(585288..585527) Helicobacter pylori Shi470 6296107 YP_001910091.1 CDS fliS NC_010698.2 585514 585894 R flagellin specific chaperone; flagellar protein FliS complement(585514..585894) Helicobacter pylori Shi470 6296856 YP_001910092.1 CDS fliD NC_010698.2 585942 587999 R involved in flagellin assembly; flagellar capping protein complement(585942..587999) Helicobacter pylori Shi470 6296413 YP_001910093.1 CDS HPSH_03075 NC_010698.2 588016 588375 R possibly involved in flagella export; flagellar protein FlaG complement(588016..588375) Helicobacter pylori Shi470 6297320 YP_001910094.1 CDS HPSH_03080 NC_010698.2 588470 589672 R COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein complement(588470..589672) Helicobacter pylori Shi470 6297123 YP_001910095.1 CDS HPSH_03085 NC_010698.2 589665 590471 R COG2177 Cell division protein; cell division membrane protein FtsX complement(589665..590471) Helicobacter pylori Shi470 6296216 YP_001910096.1 CDS HPSH_03090 NC_010698.2 590458 591129 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; cell division protein complement(590458..591129) Helicobacter pylori Shi470 6296703 YP_001910097.1 CDS trmB NC_010698.2 591126 592307 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(591126..592307) Helicobacter pylori Shi470 6296358 YP_001910098.1 CDS HPSH_03100 NC_010698.2 592318 593565 R COG3979 Uncharacterized protein contain chitin-binding domain type 3; hypothetical protein complement(592318..593565) Helicobacter pylori Shi470 6296059 YP_001910099.1 CDS HPSH_03105 NC_010698.2 593528 594511 R COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein complement(593528..594511) Helicobacter pylori Shi470 6297085 YP_001910100.1 CDS HPSH_03120 NC_010698.2 595914 597035 D COG0772 Bacterial cell division membrane protein; rod shape-determining protein MreB 595914..597035 Helicobacter pylori Shi470 6296243 YP_001910101.1 CDS HPSH_03125 NC_010698.2 597129 598085 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(597129..598085) Helicobacter pylori Shi470 6296183 YP_001910102.1 CDS HPSH_03130 NC_010698.2 598082 598153 R hypothetical protein complement(598082..598153) Helicobacter pylori Shi470 6296316 YP_001910103.1 CDS HPSH_03135 NC_010698.2 598150 598635 R COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; histidine triad (HIT) family protein complement(598150..598635) Helicobacter pylori Shi470 6296340 YP_001910104.1 CDS HPSH_03140 NC_010698.2 598645 600057 R COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-MurNac-pentapeptide presynthetase MurF complement(598645..600057) Helicobacter pylori Shi470 6296223 YP_001910105.1 CDS HPSH_03145 NC_010698.2 600113 600835 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase complement(600113..600835) Helicobacter pylori Shi470 6296312 YP_001910106.1 CDS ddl NC_010698.2 600835 601878 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(600835..601878) Helicobacter pylori Shi470 6296480 YP_001910107.1 CDS HPSH_03155 NC_010698.2 601956 602432 R COG1267 Phosphatidylglycerophosphatase A and related proteins; phosphatidylglycerophosphatase A complement(601956..602432) Helicobacter pylori Shi470 6296081 YP_001910108.1 CDS HPSH_03160 NC_010698.2 602536 603690 D COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; putative aminotransferase 602536..603690 Helicobacter pylori Shi470 6296066 YP_001910109.1 CDS HPSH_03165 NC_010698.2 603699 604160 D COG2236 Predicted phosphoribosyltransferases; xanthine guanine phosphoribosyl transferase (gpt) 603699..604160 Helicobacter pylori Shi470 6296188 YP_001910110.1 CDS HPSH_03170 NC_010698.2 604162 605481 D COG0621 2-methylthioadenine synthetase; hypothetical protein 604162..605481 Helicobacter pylori Shi470 6296122 YP_001910111.1 CDS HPSH_03175 NC_010698.2 605499 605726 D hypothetical protein 605499..605726 Helicobacter pylori Shi470 6297017 YP_001910112.1 CDS HPSH_03190 NC_010698.2 606787 607221 D hypothetical protein 606787..607221 Helicobacter pylori Shi470 6296036 YP_001910113.1 CDS HPSH_03210 NC_010698.2 608386 608691 D COG0621 2-methylthioadenine synthetase; hypothetical protein 608386..608691 Helicobacter pylori Shi470 6297137 YP_001910114.1 CDS HPSH_03215 NC_010698.2 608700 609767 D hypothetical protein 608700..609767 Helicobacter pylori Shi470 6296342 YP_001910115.1 CDS HPSH_03220 NC_010698.2 609790 610821 D COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; hypothetical protein 609790..610821 Helicobacter pylori Shi470 6296242 YP_001910116.1 CDS HPSH_03225 NC_010698.2 610915 611901 D COG0042 tRNA-dihydrouridine synthase; transcriptional regulator 610915..611901 Helicobacter pylori Shi470 6296411 YP_001910117.1 CDS HPSH_03230 NC_010698.2 611871 612788 D outer membrane protein 611871..612788 Helicobacter pylori Shi470 6296255 YP_001910118.1 CDS HPSH_03245 NC_010698.2 615029 616360 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(615029..616360) Helicobacter pylori Shi470 6296189 YP_001910119.1 CDS HPSH_03250 NC_010698.2 616445 617437 D COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; L-asparaginase II 616445..617437 Helicobacter pylori Shi470 6296416 YP_001910120.1 CDS HPSH_03255 NC_010698.2 617446 617643 R hypothetical protein complement(617446..617643) Helicobacter pylori Shi470 6296078 YP_001910121.1 CDS HPSH_03260 NC_010698.2 617777 617884 R hypothetical protein complement(617777..617884) Helicobacter pylori Shi470 6296076 YP_001910122.1 CDS HPSH_03265 NC_010698.2 617969 618439 R hypothetical protein complement(617969..618439) Helicobacter pylori Shi470 6296341 YP_001910123.1 CDS HPSH_03270 NC_010698.2 618468 618890 R hypothetical protein complement(618468..618890) Helicobacter pylori Shi470 6296249 YP_001910124.1 CDS HPSH_03275 NC_010698.2 619157 619789 D COG1279 Lysine efflux permease; hypothetical protein 619157..619789 Helicobacter pylori Shi470 6296139 YP_001910125.1 CDS HPSH_03280 NC_010698.2 619858 621573 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 619858..621573 Helicobacter pylori Shi470 6296246 YP_001910126.1 CDS HPSH_03285 NC_010698.2 621570 621971 D COG0802 Predicted ATPase or kinase; hypothetical protein 621570..621971 Helicobacter pylori Shi470 6296314 YP_001910127.1 CDS HPSH_03290 NC_010698.2 621984 622706 D COG1137 ABC-type (unclassified) transport system, ATPase component; putative ABC transporter ATP-binding protein 621984..622706 Helicobacter pylori Shi470 6297324 YP_001910128.1 CDS HPSH_03295 NC_010698.2 622709 623953 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 622709..623953 Helicobacter pylori Shi470 6296247 YP_001910129.1 CDS HPSH_03300 NC_010698.2 624274 625188 D COG1012 NAD-dependent aldehyde dehydrogenases; outer membrane protein HopH 624274..625188 Helicobacter pylori Shi470 6297275 YP_001910130.1 CDS HPSH_03305 NC_010698.2 625296 626516 R COG1896 Predicted hydrolases of HD superfamily; hypothetical protein complement(625296..626516) Helicobacter pylori Shi470 6296257 YP_001910131.1 CDS HPSH_03310 NC_010698.2 626961 627863 R COG1912 Uncharacterized conserved protein; hypothetical protein complement(626961..627863) Helicobacter pylori Shi470 6296019 YP_001910132.1 CDS HPSH_03315 NC_010698.2 628108 628452 R hypothetical protein complement(628108..628452) Helicobacter pylori Shi470 6297325 YP_001910133.1 CDS mraW NC_010698.2 628472 629398 R COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW complement(628472..629398) Helicobacter pylori Shi470 6296984 YP_001910134.1 CDS HPSH_03325 NC_010698.2 629598 630410 R Outer membrane protein/porin complement(629598..630410) Helicobacter pylori Shi470 6296925 YP_001910135.1 CDS uvrA NC_010698.2 630594 633419 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 630594..633419 Helicobacter pylori Shi470 6297382 YP_001910136.1 CDS HPSH_03335 NC_010698.2 633606 634427 R hypothetical protein complement(633606..634427) Helicobacter pylori Shi470 6296261 YP_001910137.1 CDS HPSH_03340 NC_010698.2 634532 635677 R COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; transcriptional activator of flagella proteins complement(634532..635677) Helicobacter pylori Shi470 6296866 YP_001910138.1 CDS HPSH_03345 NC_010698.2 635674 636129 R hypothetical protein complement(635674..636129) Helicobacter pylori Shi470 6297077 YP_001910139.1 CDS HPSH_03350 NC_010698.2 636147 638627 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(636147..638627) Helicobacter pylori Shi470 6296014 YP_001910140.1 CDS HPSH_03355 NC_010698.2 638647 639033 R COG0818 Diacylglycerol kinase; diacylglycerol kinase complement(638647..639033) Helicobacter pylori Shi470 6296380 YP_001910141.1 CDS HPSH_03360 NC_010698.2 639026 640039 R hypothetical protein complement(639026..640039) Helicobacter pylori Shi470 6297167 YP_001910142.1 CDS HPSH_03365 NC_010698.2 640362 640862 R COG4647 Acetone carboxylase, gamma subunit; hypothetical protein complement(640362..640862) Helicobacter pylori Shi470 6296015 YP_001910143.1 CDS HPSH_03370 NC_010698.2 640879 643176 R COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit; N-methylhydantoinase complement(640879..643176) Helicobacter pylori Shi470 6296391 YP_001910144.1 CDS HPSH_03375 NC_010698.2 643188 645329 R COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit; hydantoin utilization protein A complement(643188..645329) Helicobacter pylori Shi470 6296301 YP_001910145.1 CDS HPSH_03380 NC_010698.2 645548 646549 R COG3528 Uncharacterized protein conserved in bacteria; putative outer membrane protein complement(645548..646549) Helicobacter pylori Shi470 6296311 YP_001910146.1 CDS HPSH_03385 NC_010698.2 646676 648040 R COG2031 Short chain fatty acids transporter; short-chain fatty acids transporter complement(646676..648040) Helicobacter pylori Shi470 6296033 YP_001910147.1 CDS HPSH_03390 NC_010698.2 647961 648104 D hypothetical protein 647961..648104 Helicobacter pylori Shi470 6296357 YP_001910148.1 CDS HPSH_03395 NC_010698.2 648059 648682 R COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit; succinyl-CoA-transferase subunit B complement(648059..648682) Helicobacter pylori Shi470 6296570 YP_001910149.1 CDS HPSH_03400 NC_010698.2 648679 649377 R COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; 3-oxoacid Coa-transferase subunit A complement(648679..649377) Helicobacter pylori Shi470 6296267 YP_001910150.1 CDS HPSH_03405 NC_010698.2 649388 650563 R COG0183 Acetyl-CoA acetyltransferase; acetyl coenzyme A acetyltransferase FadA complement(649388..650563) Helicobacter pylori Shi470 6297027 YP_001910151.1 CDS HPSH_03410 NC_010698.2 650820 651221 R COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; hypothetical protein complement(650820..651221) Helicobacter pylori Shi470 6296278 YP_001910152.1 CDS HPSH_03415 NC_010698.2 651311 652183 R putative type II restriction enzyme complement(651311..652183) Helicobacter pylori Shi470 6296398 YP_001910153.1 CDS HPSH_03420 NC_010698.2 652186 653400 R COG0863 DNA modification methylase; putative type II cytosine specific methyltransferase complement(652186..653400) Helicobacter pylori Shi470 6296266 YP_001910154.1 CDS HPSH_03425 NC_010698.2 653455 654267 R COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; hypothetical protein complement(653455..654267) Helicobacter pylori Shi470 6296113 YP_001910155.1 CDS HPSH_03430 NC_010698.2 654393 656339 D COG0370 Fe2+ transport system protein B; iron(II) transport protein 654393..656339 Helicobacter pylori Shi470 6297158 YP_001910156.1 CDS HPSH_03435 NC_010698.2 656582 658885 D COG4772 Outer membrane receptor for Fe3+-dicitrate; iron(III) dicitrate transport protein 656582..658885 Helicobacter pylori Shi470 6297298 YP_001910157.1 CDS fliP NC_010698.2 658924 659670 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(658924..659670) Helicobacter pylori Shi470 6296487 YP_001910158.1 CDS HPSH_03445 NC_010698.2 659649 659801 R hypothetical protein complement(659649..659801) Helicobacter pylori Shi470 6297280 YP_001910159.1 CDS glmU NC_010698.2 659800 661059 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 659800..661059 Helicobacter pylori Shi470 6296486 YP_001910160.1 CDS HPSH_03455 NC_010698.2 661324 661653 D hypothetical protein 661324..661653 Helicobacter pylori Shi470 6296531 YP_001910161.1 CDS HPSH_03460 NC_010698.2 661752 662150 D hypothetical protein 661752..662150 Helicobacter pylori Shi470 6297103 YP_001910162.1 CDS HPSH_03465 NC_010698.2 662322 664688 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 662322..664688 Helicobacter pylori Shi470 6296319 YP_001910163.1 CDS HPSH_03470 NC_010698.2 664750 665697 D COG0673 Predicted dehydrogenases and related proteins; putative lipopolysaccharide biosynthesis protein 664750..665697 Helicobacter pylori Shi470 6296422 YP_001910164.1 CDS HPSH_03485 NC_010698.2 666524 667030 D COG0350 Methylated DNA-protein cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase 666524..667030 Helicobacter pylori Shi470 6297543 YP_001910165.1 CDS HPSH_03490 NC_010698.2 667093 668163 R COG0582 Integrase; integrase-recombinase protein complement(667093..668163) Helicobacter pylori Shi470 6296534 YP_001910166.1 CDS HPSH_03495 NC_010698.2 668170 668289 R hypothetical protein complement(668170..668289) Helicobacter pylori Shi470 6296330 YP_001910167.1 CDS HPSH_03500 NC_010698.2 668413 669585 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(668413..669585) Helicobacter pylori Shi470 6296269 YP_001910168.1 CDS HPSH_03505 NC_010698.2 669744 670556 R outer membrane protein HorF complement(669744..670556) Helicobacter pylori Shi470 6296524 YP_001910169.1 CDS HPSH_03510 NC_010698.2 670659 670757 R hypothetical protein complement(670659..670757) Helicobacter pylori Shi470 6296463 YP_001910170.1 CDS HPSH_03515 NC_010698.2 670800 675029 R COG4889 Predicted helicase; hypothetical protein complement(670800..675029) Helicobacter pylori Shi470 6296184 YP_001910171.1 CDS HPSH_03520 NC_010698.2 674993 675625 R COG4889 Predicted helicase; hypothetical protein complement(674993..675625) Helicobacter pylori Shi470 6296031 YP_001910172.1 CDS HPSH_03525 NC_010698.2 675703 676992 R COG0247 Fe-S oxidoreductase; anaerobic glycerol-3-phosphate dehydrogenase subunit C complement(675703..676992) Helicobacter pylori Shi470 6296288 YP_001910173.1 CDS HPSH_03530 NC_010698.2 676989 678362 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(676989..678362) Helicobacter pylori Shi470 6296365 YP_001910174.1 CDS HPSH_03535 NC_010698.2 678362 678877 R hypothetical protein complement(678362..678877) Helicobacter pylori Shi470 6296127 YP_001910175.1 CDS HPSH_03540 NC_010698.2 678915 680012 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(678915..680012) Helicobacter pylori Shi470 6297151 YP_001910176.1 CDS rnc NC_010698.2 680009 680725 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(680009..680725) Helicobacter pylori Shi470 6296226 YP_001910177.1 CDS rnhA NC_010698.2 680700 681164 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(680700..681164) Helicobacter pylori Shi470 6296163 YP_001910178.1 CDS HPSH_03555 NC_010698.2 681151 682167 R COG2956 Predicted N-acetylglucosaminyl transferase; hypothetical protein complement(681151..682167) Helicobacter pylori Shi470 6296143 YP_001910179.1 CDS HPSH_03560 NC_010698.2 682178 683458 R COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein complement(682178..683458) Helicobacter pylori Shi470 6297207 YP_001910180.1 CDS gatB NC_010698.2 683458 684882 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(683458..684882) Helicobacter pylori Shi470 6296291 YP_001910181.1 CDS HPSH_03570 NC_010698.2 684882 686180 R COG0612 Predicted Zn-dependent peptidases; processing protease complement(684882..686180) Helicobacter pylori Shi470 6297156 YP_001910182.1 CDS HPSH_03575 NC_010698.2 686183 687244 R COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; hypothetical protein complement(686183..687244) Helicobacter pylori Shi470 6297079 YP_001910183.1 CDS HPSH_03580 NC_010698.2 687246 689891 R COG4775 Outer membrane protein/protective antigen OMA87; protective surface antigen D15 complement(687246..689891) Helicobacter pylori Shi470 6296389 YP_001910184.1 CDS HPSH_03585 NC_010698.2 690064 691146 R COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; hypothetical protein complement(690064..691146) Helicobacter pylori Shi470 6297121 YP_001910185.1 CDS HPSH_03590 NC_010698.2 691440 691943 D COG1528 Ferritin-like protein; nonheme iron-containing ferritin 691440..691943 Helicobacter pylori Shi470 6297041 YP_001910186.1 CDS HPSH_03595 NC_010698.2 691959 692582 D COG0560 Phosphoserine phosphatase; phosphoserine phosphatase SerB 691959..692582 Helicobacter pylori Shi470 6296128 YP_001910187.1 CDS HPSH_03600 NC_010698.2 692629 692712 D hypothetical protein 692629..692712 Helicobacter pylori Shi470 6296265 YP_001910188.1 CDS HPSH_03605 NC_010698.2 692721 693905 D alpha-(1,3)-fucosyltransferase 692721..693905 Helicobacter pylori Shi470 6296144 YP_001910189.1 CDS HPSH_03610 NC_010698.2 693914 694492 R COG1573 Uracil-DNA glycosylase; hypothetical protein complement(693914..694492) Helicobacter pylori Shi470 6296902 YP_001910190.1 CDS aspA NC_010698.2 694549 695955 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(694549..695955) Helicobacter pylori Shi470 6296118 YP_001910191.1 CDS HPSH_03620 NC_010698.2 696010 697278 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(696010..697278) Helicobacter pylori Shi470 6297157 YP_001910192.1 CDS HPSH_03625 NC_010698.2 697281 697688 R hypothetical protein complement(697281..697688) Helicobacter pylori Shi470 6296150 YP_001910193.1 CDS HPSH_03630 NC_010698.2 697700 698521 R COG1210 UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase complement(697700..698521) Helicobacter pylori Shi470 6297323 YP_001910194.1 CDS HPSH_03635 NC_010698.2 698518 700200 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); soluble lytic murein transglycosylase complement(698518..700200) Helicobacter pylori Shi470 6296397 YP_001910195.1 CDS HPSH_03640 NC_010698.2 700209 700502 R COG0762 Predicted integral membrane protein; hypothetical protein complement(700209..700502) Helicobacter pylori Shi470 6296235 YP_001910196.1 CDS HPSH_03645 NC_010698.2 700499 701818 R charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase complement(700499..701818) Helicobacter pylori Shi470 6296339 YP_001910197.1 CDS HPSH_03660 NC_010698.2 702712 702843 R hypothetical protein complement(702712..702843) Helicobacter pylori Shi470 6296158 YP_001910198.1 CDS HPSH_03665 NC_010698.2 702902 704068 R COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; poly(A) polymerase complement(702902..704068) Helicobacter pylori Shi470 6296903 YP_001910199.1 CDS HPSH_03670 NC_010698.2 704130 704810 D COG0603 Predicted PP-loop superfamily ATPase; ExsB trans-regulatory protein 704130..704810 Helicobacter pylori Shi470 6297089 YP_001910200.1 CDS HPSH_03675 NC_010698.2 704856 705155 R outer membrane protein HopH complement(704856..705155) Helicobacter pylori Shi470 6297201 YP_001910201.1 CDS HPSH_03680 NC_010698.2 705979 706431 D hypothetical protein 705979..706431 Helicobacter pylori Shi470 6296084 YP_001910202.1 CDS HPSH_03685 NC_010698.2 706546 706959 D hypothetical protein 706546..706959 Helicobacter pylori Shi470 6296054 YP_001910203.1 CDS HPSH_03690 NC_010698.2 706964 708502 R hypothetical protein complement(706964..708502) Helicobacter pylori Shi470 6297194 YP_001910204.1 CDS HPSH_03695 NC_010698.2 708504 709040 R COG0680 Ni,Fe-hydrogenase maturation factor; Hydrogenase expression/formation protein complement(708504..709040) Helicobacter pylori Shi470 6296569 YP_001910205.1 CDS HPSH_03700 NC_010698.2 709037 709711 R COG1969 Ni,Fe-hydrogenase I cytochrome b subunit; quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit HydC complement(709037..709711) Helicobacter pylori Shi470 6296521 YP_001910206.1 CDS HPSH_03705 NC_010698.2 709724 711460 R COG0374 Ni,Fe-hydrogenase I large subunit; quinone-reactive Ni/Fe hydrogenase HydB complement(709724..711460) Helicobacter pylori Shi470 6297024 YP_001910207.1 CDS HPSH_03710 NC_010698.2 711477 712631 R COG1740 Ni,Fe-hydrogenase I small subunit; Hydrogenase, small subunit complement(711477..712631) Helicobacter pylori Shi470 6296111 YP_001910208.1 CDS HPSH_03715 NC_010698.2 712766 713350 D COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); modulator of drug activity 712766..713350 Helicobacter pylori Shi470 6297038 YP_001910209.1 CDS HPSH_03720 NC_010698.2 713397 715442 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(713397..715442) Helicobacter pylori Shi470 6296213 YP_001910210.1 CDS HPSH_03725 NC_010698.2 715567 716625 R COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein F complement(715567..716625) Helicobacter pylori Shi470 6295999 YP_001910211.1 CDS HPSH_03730 NC_010698.2 716637 717842 R COG2171 Tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate N-succinyltransferase DapD complement(716637..717842) Helicobacter pylori Shi470 6296010 YP_001910212.1 CDS ispG NC_010698.2 717845 718924 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(717845..718924) Helicobacter pylori Shi470 6296350 YP_001910213.1 CDS HPSH_03740 NC_010698.2 719044 720171 D COG0436 Aspartate/tyrosine/aromatic aminotransferase; hypothetical protein 719044..720171 Helicobacter pylori Shi470 6296290 YP_001910214.1 CDS murC NC_010698.2 720164 721513 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 720164..721513 Helicobacter pylori Shi470 6296240 YP_001910215.1 CDS HPSH_03750 NC_010698.2 721513 721878 D hypothetical protein 721513..721878 Helicobacter pylori Shi470 6296983 YP_001910216.1 CDS HPSH_03755 NC_010698.2 721885 724134 D MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 721885..724134 Helicobacter pylori Shi470 6296093 YP_001910217.1 CDS HPSH_03760 NC_010698.2 724282 724803 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(724282..724803) Helicobacter pylori Shi470 6296221 YP_001910218.1 CDS HPSH_03765 NC_010698.2 724859 725614 R COG0840 Methyl-accepting chemotaxis protein; putative lipopolysaccharide biosynthesis protein complement(724859..725614) Helicobacter pylori Shi470 6296212 YP_001910219.1 CDS HPSH_03770 NC_010698.2 725560 726210 R COG3306 Glycosyltransferase involved in LPS biosynthesis; putative lipopolysaccharide biosynthesis protein complement(725560..726210) Helicobacter pylori Shi470 6296325 YP_001910220.1 CDS HPSH_03775 NC_010698.2 726217 727215 R COG3306 Glycosyltransferase involved in LPS biosynthesis; putative lipopolysaccharide biosynthesis protein complement(726217..727215) Helicobacter pylori Shi470 6296231 YP_001910221.1 CDS adk NC_010698.2 727240 727815 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(727240..727815) Helicobacter pylori Shi470 6296256 YP_001910222.1 CDS aspS NC_010698.2 727832 729565 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(727832..729565) Helicobacter pylori Shi470 6296229 YP_001910223.1 CDS HPSH_03790 NC_010698.2 729600 730541 R COG0835 Chemotaxis signal transduction protein; chemotaxis protein complement(729600..730541) Helicobacter pylori Shi470 6296200 YP_001910224.1 CDS ligA NC_010698.2 730619 732589 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 730619..732589 Helicobacter pylori Shi470 6297250 YP_001910225.1 CDS HPSH_03800 NC_010698.2 732690 733022 D COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; hypothetical protein 732690..733022 Helicobacter pylori Shi470 6296016 YP_001910226.1 CDS HPSH_03805 NC_010698.2 733594 734052 D COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 733594..734052 Helicobacter pylori Shi470 6296490 YP_001910227.1 CDS HPSH_03810 NC_010698.2 734052 734801 D COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 734052..734801 Helicobacter pylori Shi470 6296009 YP_001910228.1 CDS HPSH_03815 NC_010698.2 734861 744430 R putative vacuolating cytotoxin (VacA)-like protein complement(734861..744430) Helicobacter pylori Shi470 6297033 YP_001910229.1 CDS HPSH_03820 NC_010698.2 744569 745138 R COG0015 Adenylosuccinate lyase; hypothetical protein complement(744569..745138) Helicobacter pylori Shi470 6296466 YP_001910230.1 CDS HPSH_03825 NC_010698.2 745135 748221 R COG0841 Cation/multidrug efflux pump; cytoplasmic pump protein of the hefABC efflux system HefC complement(745135..748221) Helicobacter pylori Shi470 6297122 YP_001910231.1 CDS HPSH_03830 NC_010698.2 748234 748938 R COG0845 Membrane-fusion protein; membrane fusion protein of the hefABC efflux system HefB complement(748234..748938) Helicobacter pylori Shi470 6297139 YP_001910232.1 CDS HPSH_03835 NC_010698.2 748948 750381 R COG1538 Outer membrane protein; outer-membrane protein of the hefABC efflux system HefA complement(748948..750381) Helicobacter pylori Shi470 6296251 YP_001910233.1 CDS hemE NC_010698.2 750392 751411 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(750392..751411) Helicobacter pylori Shi470 6296136 YP_001910234.1 CDS HPSH_03845 NC_010698.2 751477 752046 R hypothetical protein complement(751477..752046) Helicobacter pylori Shi470 6296346 YP_001910235.1 CDS HPSH_03850 NC_010698.2 752091 752747 R COG2231 Uncharacterized protein related to Endonuclease III; 3-methyladenine DNA glycosylase complement(752091..752747) Helicobacter pylori Shi470 6296407 YP_001910236.1 CDS HPSH_03855 NC_010698.2 752865 754397 R FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A complement(752865..754397) Helicobacter pylori Shi470 6297500 YP_001910237.1 CDS HPSH_03860 NC_010698.2 754561 755325 D COG1132 ABC-type multidrug transport system, ATPase and permease components; putative secretion/efflux ABC transporter ATP-binding protein 754561..755325 Helicobacter pylori Shi470 6296840 YP_001910238.1 CDS HPSH_03865 NC_010698.2 755395 756342 D COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein SpaB 755395..756342 Helicobacter pylori Shi470 6296308 YP_001910239.1 CDS HPSH_03870 NC_010698.2 756414 757715 D COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein 756414..757715 Helicobacter pylori Shi470 6296087 YP_001910240.1 CDS HPSH_03875 NC_010698.2 757738 758859 D COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase BioF 757738..758859 Helicobacter pylori Shi470 6296526 YP_001910241.1 CDS HPSH_03880 NC_010698.2 758859 760838 D COG0744 Membrane carboxypeptidase (penicillin-binding protein); penicillin-binding protein 1A 758859..760838 Helicobacter pylori Shi470 6296089 YP_001910242.1 CDS HPSH_03885 NC_010698.2 760841 761419 R Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein complement(760841..761419) Helicobacter pylori Shi470 6297179 YP_001910243.1 CDS HPSH_03890 NC_010698.2 761578 761697 D hypothetical protein 761578..761697 Helicobacter pylori Shi470 6297063 YP_001910244.1 CDS HPSH_03895 NC_010698.2 761895 763367 R COG1495 Disulfide bond formation protein DsbB; DsbB-like protein complement(761895..763367) Helicobacter pylori Shi470 6296313 YP_001910245.1 CDS HPSH_03900 NC_010698.2 763376 763540 R hypothetical protein complement(763376..763540) Helicobacter pylori Shi470 6296178 YP_001910246.1 CDS HPSH_03905 NC_010698.2 763680 765458 R COG5610 Predicted hydrolase (HAD superfamily); hypothetical protein complement(763680..765458) Helicobacter pylori Shi470 6297305 YP_001910247.1 CDS oorC NC_010698.2 765566 766120 R COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; 2-oxoglutarate-acceptor oxidoreductase subunit OorC complement(765566..766120) Helicobacter pylori Shi470 6296182 YP_001910248.1 CDS oorB NC_010698.2 766120 766941 R COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; 2-oxoglutarate-acceptor oxidoreductase subunit OorB complement(766120..766941) Helicobacter pylori Shi470 6296408 YP_001910249.1 CDS oorA NC_010698.2 766943 768070 R COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; 2-oxoglutarate-acceptor oxidoreductase subunit OorA complement(766943..768070) Helicobacter pylori Shi470 6296106 YP_001910250.1 CDS oorD NC_010698.2 768070 768411 R COG1146 Ferredoxin; 2-oxoglutarate-acceptor oxidoreductase subunit OorD complement(768070..768411) Helicobacter pylori Shi470 6296452 YP_001910251.1 CDS HPSH_03930 NC_010698.2 768399 768491 R hypothetical protein complement(768399..768491) Helicobacter pylori Shi470 6296125 YP_001910252.1 CDS HPSH_03935 NC_010698.2 768587 769519 R COG1559 Predicted periplasmic solute-binding protein; aminodeoxychorismate lyase PabC complement(768587..769519) Helicobacter pylori Shi470 6296387 YP_001910253.1 CDS HPSH_03940 NC_010698.2 769500 772433 D hypothetical protein 769500..772433 Helicobacter pylori Shi470 6296137 YP_001910254.1 CDS HPSH_03945 NC_010698.2 772435 772665 D COG1918 Fe2+ transport system protein A; hypothetical protein 772435..772665 Helicobacter pylori Shi470 6296153 YP_001910255.1 CDS HPSH_03950 NC_010698.2 772662 773318 D COG0177 Predicted EndoIII-related endonuclease; endonuclease III 772662..773318 Helicobacter pylori Shi470 6296924 YP_001910256.1 CDS HPSH_03955 NC_010698.2 773400 773771 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 773400..773771 Helicobacter pylori Shi470 6296399 YP_001910257.1 CDS HPSH_03960 NC_010698.2 773783 774649 D hypothetical protein 773783..774649 Helicobacter pylori Shi470 6297366 YP_001910258.1 CDS HPSH_03965 NC_010698.2 774633 775580 D COG0810 Periplasmic protein TonB, links inner and outer membranes; hypothetical protein 774633..775580 Helicobacter pylori Shi470 6297047 YP_001910259.1 CDS HPSH_03970 NC_010698.2 775584 776603 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 775584..776603 Helicobacter pylori Shi470 6296453 YP_001910260.1 CDS HPSH_03975 NC_010698.2 776579 777697 D COG4692 Predicted neuraminidase (sialidase); hypothetical protein 776579..777697 Helicobacter pylori Shi470 6296185 YP_001910261.1 CDS HPSH_03980 NC_010698.2 777704 778258 D hypothetical protein 777704..778258 Helicobacter pylori Shi470 6296073 YP_001910262.1 CDS HPSH_03985 NC_010698.2 778264 780291 D COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; hypothetical protein 778264..780291 Helicobacter pylori Shi470 6296296 YP_001910263.1 CDS HPSH_03990 NC_010698.2 780368 781240 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 780368..781240 Helicobacter pylori Shi470 6296414 YP_001910264.1 CDS HPSH_03995 NC_010698.2 781241 782113 D COG0681 Signal peptidase I; signal peptidase I (lepB) 781241..782113 Helicobacter pylori Shi470 6296039 YP_001910265.1 CDS HPSH_04000 NC_010698.2 782122 782820 D COG1994 Zn-dependent proteases; hypothetical protein 782122..782820 Helicobacter pylori Shi470 6297090 YP_001910266.1 CDS HPSH_04005 NC_010698.2 782841 783296 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 782841..783296 Helicobacter pylori Shi470 6297599 YP_001910267.1 CDS HPSH_04010 NC_010698.2 783349 783681 D hypothetical protein 783349..783681 Helicobacter pylori Shi470 6297598 YP_001910268.1 CDS HPSH_04015 NC_010698.2 783739 784278 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 783739..784278 Helicobacter pylori Shi470 6297597 YP_001910269.1 CDS HPSH_04020 NC_010698.2 784293 784871 D COG0586 Uncharacterized membrane-associated protein; hypothetical protein 784293..784871 Helicobacter pylori Shi470 6297596 YP_001910270.1 CDS HPSH_04025 NC_010698.2 784933 786423 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 784933..786423 Helicobacter pylori Shi470 6297595 YP_001910271.1 CDS HPSH_04030 NC_010698.2 786425 787525 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 786425..787525 Helicobacter pylori Shi470 6297594 YP_001910272.1 CDS HPSH_04035 NC_010698.2 787559 788431 D COG0535 Predicted Fe-S oxidoreductases; hypothetical protein 787559..788431 Helicobacter pylori Shi470 6297579 YP_001910273.1 CDS HPSH_04040 NC_010698.2 788507 789553 R COG0628 Predicted permease; membrane protein complement(788507..789553) Helicobacter pylori Shi470 6296303 YP_001910274.1 CDS dapF NC_010698.2 789668 790489 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 789668..790489 Helicobacter pylori Shi470 6297048 YP_001910275.1 CDS HPSH_04050 NC_010698.2 790596 791243 D COG3059 Predicted membrane protein; hypothetical protein 790596..791243 Helicobacter pylori Shi470 6297592 YP_001910276.1 CDS HPSH_04055 NC_010698.2 791267 791509 R hypothetical protein complement(791267..791509) Helicobacter pylori Shi470 6297591 YP_001910277.1 CDS HPSH_04060 NC_010698.2 791682 792932 D hypothetical protein 791682..792932 Helicobacter pylori Shi470 6297590 YP_001910278.1 CDS rpsU NC_010698.2 793034 793246 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 793034..793246 Helicobacter pylori Shi470 6297589 YP_001910279.1 CDS fabG NC_010698.2 793283 794026 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 793283..794026 Helicobacter pylori Shi470 6297588 YP_001910280.1 CDS acpP NC_010698.2 794256 794492 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 794256..794492 Helicobacter pylori Shi470 6297587 YP_001910281.1 CDS HPSH_04080 NC_010698.2 794682 794789 D hypothetical protein 794682..794789 Helicobacter pylori Shi470 6297586 YP_001910282.1 CDS HPSH_04085 NC_010698.2 794805 796043 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 794805..796043 Helicobacter pylori Shi470 6297585 YP_001910283.1 CDS HPSH_04090 NC_010698.2 796066 797004 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 796066..797004 Helicobacter pylori Shi470 6297584 YP_001910284.1 CDS HPSH_04095 NC_010698.2 797117 797206 D hypothetical protein 797117..797206 Helicobacter pylori Shi470 6297583 YP_001910286.1 CDS HPSH_04105 NC_010698.2 797415 797612 D hypothetical protein 797415..797612 Helicobacter pylori Shi470 6297581 YP_001910287.1 CDS HPSH_04110 NC_010698.2 797699 798520 R hypothetical protein complement(797699..798520) Helicobacter pylori Shi470 6297580 YP_001910288.1 CDS HPSH_04115 NC_010698.2 798517 799491 R hypothetical protein complement(798517..799491) Helicobacter pylori Shi470 6297593 YP_001910289.1 CDS HPSH_04120 NC_010698.2 799504 800187 R COG0566 rRNA methylases; hypothetical protein complement(799504..800187) Helicobacter pylori Shi470 6297576 YP_001910290.1 CDS HPSH_04125 NC_010698.2 800200 801063 R COG0313 Predicted methyltransferases; hypothetical protein complement(800200..801063) Helicobacter pylori Shi470 6297575 YP_001910291.1 CDS rpmE NC_010698.2 801088 801291 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(801088..801291) Helicobacter pylori Shi470 6297574 YP_001910292.1 CDS rho NC_010698.2 801553 802869 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 801553..802869 Helicobacter pylori Shi470 6297573 YP_001910293.1 CDS HPSH_04140 NC_010698.2 802905 803672 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 802905..803672 Helicobacter pylori Shi470 6297572 YP_001910294.1 CDS HPSH_04145 NC_010698.2 804109 807594 R cag pathogenicity island protein CagA complement(804109..807594) Helicobacter pylori Shi470 6297571 YP_001910295.1 CDS HPSH_04150 NC_010698.2 808001 808228 D cag pathogenicity island protein CagB 808001..808228 Helicobacter pylori Shi470 6297570 YP_001910296.1 CDS HPSH_04155 NC_010698.2 808395 808742 D cag pathogenicity island protein CagC 808395..808742 Helicobacter pylori Shi470 6297569 YP_001910297.1 CDS HPSH_04160 NC_010698.2 808744 809367 D cag pathogenicity island protein CagD 808744..809367 Helicobacter pylori Shi470 6297568 YP_001910298.1 CDS HPSH_04165 NC_010698.2 809382 812327 D COG3451 Type IV secretory pathway, VirB4 components; cag pathogenicity island protein CagE 809382..812327 Helicobacter pylori Shi470 6297567 YP_001910299.1 CDS HPSH_04170 NC_010698.2 812329 813135 D cag pathogenicity island protein CagF 812329..813135 Helicobacter pylori Shi470 6297566 YP_001910300.1 CDS HPSH_04175 NC_010698.2 813190 813621 D cag pathogenicity island protein CagG 813190..813621 Helicobacter pylori Shi470 6297565 YP_001910301.1 CDS HPSH_04180 NC_010698.2 813607 813804 R hypothetical protein complement(813607..813804) Helicobacter pylori Shi470 6297564 YP_001910302.1 CDS HPSH_04185 NC_010698.2 813803 814735 D COG0249 Mismatch repair ATPase (MutS family); cag pathogenicity island protein CagH 813803..814735 Helicobacter pylori Shi470 6297563 YP_001910303.1 CDS HPSH_04190 NC_010698.2 814746 815885 D cag pathogenicity island protein CagI 814746..815885 Helicobacter pylori Shi470 6297562 YP_001910304.1 CDS HPSH_04195 NC_010698.2 815882 816595 D cag pathogenicity island protein CagL 815882..816595 Helicobacter pylori Shi470 6297561 YP_001910305.1 CDS HPSH_04200 NC_010698.2 816678 817598 R cag pathogenicity island protein CagN complement(816678..817598) Helicobacter pylori Shi470 6297560 YP_001910306.1 CDS HPSH_04205 NC_010698.2 817613 818743 R cag pathogenicity island protein CagM complement(817613..818743) Helicobacter pylori Shi470 6297559 YP_001910307.1 CDS HPSH_04210 NC_010698.2 819169 819513 D cag pathogenicity island protein CagP 819169..819513 Helicobacter pylori Shi470 6297558 YP_001910308.1 CDS HPSH_04215 NC_010698.2 819912 823169 R cag pathogenicity island protein CagA complement(819912..823169) Helicobacter pylori Shi470 6297557 YP_001910309.1 CDS HPSH_04220 NC_010698.2 823362 823460 D hypothetical protein 823362..823460 Helicobacter pylori Shi470 6297458 YP_001910310.1 CDS HPSH_04225 NC_010698.2 823481 823708 D cag pathogenicity island protein CagB 823481..823708 Helicobacter pylori Shi470 6296919 YP_001910311.1 CDS HPSH_04230 NC_010698.2 823876 824067 D cag pathogenicity island protein CagC 823876..824067 Helicobacter pylori Shi470 6296543 YP_001910312.1 CDS HPSH_04235 NC_010698.2 824137 824232 D hypothetical protein 824137..824232 Helicobacter pylori Shi470 6297555 YP_001910313.1 CDS HPSH_04240 NC_010698.2 824858 825163 R cag pathogenicity island protein CagQ complement(824858..825163) Helicobacter pylori Shi470 6297554 YP_001910314.1 CDS HPSH_04245 NC_010698.2 825192 825374 R hypothetical protein complement(825192..825374) Helicobacter pylori Shi470 6297553 YP_001910315.1 CDS HPSH_04250 NC_010698.2 825507 825644 D hypothetical protein 825507..825644 Helicobacter pylori Shi470 6297552 YP_001910316.1 CDS HPSH_04255 NC_010698.2 826078 826677 D cag pathogenicity island protein CagS 826078..826677 Helicobacter pylori Shi470 6297551 YP_001910317.1 CDS HPSH_04260 NC_010698.2 826879 827721 R cag pathogenicity island protein CagT complement(826879..827721) Helicobacter pylori Shi470 6297550 YP_001910318.1 CDS HPSH_04265 NC_010698.2 827737 828384 R cag pathogenicity island protein CagU complement(827737..828384) Helicobacter pylori Shi470 6297549 YP_001910319.1 CDS HPSH_04270 NC_010698.2 828660 829418 D COG3736 Type IV secretory pathway, component VirB8; cag pathogenicity island protein CagV 828660..829418 Helicobacter pylori Shi470 6297548 YP_001910320.1 CDS HPSH_04275 NC_010698.2 829423 831030 D cag pathogenicity island protein CagW 829423..831030 Helicobacter pylori Shi470 6297547 YP_001910321.1 CDS HPSH_04280 NC_010698.2 831082 832650 D COG3504 Type IV secretory pathway, VirB9 components; cag pathogenicity island protein CagX 831082..832650 Helicobacter pylori Shi470 6297546 YP_001910322.1 CDS HPSH_04285 NC_010698.2 832665 838229 D COG2948 Type IV secretory pathway, VirB10 components; cag pathogenicity island protein CagY 832665..838229 Helicobacter pylori Shi470 6297545 YP_001910323.1 CDS HPSH_04290 NC_010698.2 838219 838353 D hypothetical protein 838219..838353 Helicobacter pylori Shi470 6297544 YP_001910324.1 CDS HPSH_04295 NC_010698.2 838366 838965 D cag pathogenicity island protein CagZ 838366..838965 Helicobacter pylori Shi470 6296021 YP_001910325.1 CDS HPSH_04300 NC_010698.2 838970 839962 D COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; cag pathogenicity island protein cag alpha 838970..839962 Helicobacter pylori Shi470 6297539 YP_001910326.1 CDS HPSH_04305 NC_010698.2 839971 842217 D COG3505 Type IV secretory pathway, VirD4 components; cag pathogenicity island protein Cag beta 839971..842217 Helicobacter pylori Shi470 6297538 YP_001910327.1 CDS HPSH_04310 NC_010698.2 842336 842716 R cag pathogenicity island protein Cag gamma complement(842336..842716) Helicobacter pylori Shi470 6297537 YP_001910328.1 CDS HPSH_04315 NC_010698.2 842855 844300 R cag pathogenicity island protein Cag delta complement(842855..844300) Helicobacter pylori Shi470 6297536 YP_001910329.1 CDS HPSH_04320 NC_010698.2 844314 844511 R cag pathogenicity island protein Cag theta complement(844314..844511) Helicobacter pylori Shi470 6297535 YP_001910330.1 CDS HPSH_04325 NC_010698.2 844527 844874 R cag pathogenicity island protein Cag zeta complement(844527..844874) Helicobacter pylori Shi470 6297533 YP_001910331.1 CDS HPSH_04330 NC_010698.2 845087 845917 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 845087..845917 Helicobacter pylori Shi470 6297531 YP_001910332.1 CDS HPSH_04335 NC_010698.2 845992 846984 R COG3034 Uncharacterized protein conserved in bacteria; hypothetical protein complement(845992..846984) Helicobacter pylori Shi470 6297530 YP_001910333.1 CDS era NC_010698.2 846981 847886 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(846981..847886) Helicobacter pylori Shi470 6297529 YP_001910334.1 CDS hslU NC_010698.2 847886 849217 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(847886..849217) Helicobacter pylori Shi470 6297528 YP_001910335.1 CDS HPSH_04350 NC_010698.2 849217 849759 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(849217..849759) Helicobacter pylori Shi470 6297526 YP_001910336.1 CDS rplI NC_010698.2 849763 850212 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(849763..850212) Helicobacter pylori Shi470 6297525 YP_001910337.1 CDS HPSH_04360 NC_010698.2 850275 852344 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(850275..852344) Helicobacter pylori Shi470 6297524 YP_001910338.1 CDS HPSH_04365 NC_010698.2 852479 853924 D COG0174 Glutamine synthetase; glutamine synthetase 852479..853924 Helicobacter pylori Shi470 6297523 YP_001910339.1 CDS HPSH_04370 NC_010698.2 854202 854282 R hypothetical protein complement(854202..854282) Helicobacter pylori Shi470 6297522 YP_001910340.1 CDS HPSH_04375 NC_010698.2 854616 855380 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(854616..855380) Helicobacter pylori Shi470 6297521 YP_001910341.1 CDS HPSH_04380 NC_010698.2 855403 856782 R COG0277 FAD/FMN-containing dehydrogenases; putative glycolate oxidase complement(855403..856782) Helicobacter pylori Shi470 6297520 YP_001910342.1 CDS HPSH_04385 NC_010698.2 856784 858091 R plasminogen binding protein complement(856784..858091) Helicobacter pylori Shi470 6297519 YP_001910343.1 CDS HPSH_04390 NC_010698.2 858102 858740 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; hypothetical protein complement(858102..858740) Helicobacter pylori Shi470 6297518 YP_001910344.1 CDS HPSH_04395 NC_010698.2 858740 859948 R COG0739 Membrane proteins related to metalloendopeptidases; putative outer membrane protein complement(858740..859948) Helicobacter pylori Shi470 6297338 YP_001910345.1 CDS HPSH_04400 NC_010698.2 860422 860805 D hypothetical protein 860422..860805 Helicobacter pylori Shi470 6297542 YP_001910346.1 CDS HPSH_04405 NC_010698.2 860819 860893 R hypothetical protein complement(860819..860893) Helicobacter pylori Shi470 6297241 YP_001910347.1 CDS gyrB NC_010698.2 860900 863221 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(860900..863221) Helicobacter pylori Shi470 6297516 YP_001910348.1 CDS HPSH_04415 NC_010698.2 863233 864357 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(863233..864357) Helicobacter pylori Shi470 6297515 YP_001910349.1 CDS HPSH_04420 NC_010698.2 864415 865482 R COG2829 Outer membrane phospholipase A; phospholipase A1 complement(864415..865482) Helicobacter pylori Shi470 6297514 YP_001910350.1 CDS HPSH_04425 NC_010698.2 865497 866825 R COG0733 Na+-dependent transporters of the SNF family; sodium- and chloride-dependent transporter complement(865497..866825) Helicobacter pylori Shi470 6297513 YP_001910351.1 CDS HPSH_04430 NC_010698.2 866836 868164 R COG0733 Na+-dependent transporters of the SNF family; sodium- and chloride-dependent transporter complement(866836..868164) Helicobacter pylori Shi470 6297512 YP_001910352.1 CDS HPSH_04435 NC_010698.2 868394 868795 D COG0824 Predicted thioesterase; hypothetical protein 868394..868795 Helicobacter pylori Shi470 6297511 YP_001910353.1 CDS HPSH_04440 NC_010698.2 868785 869045 D hypothetical protein 868785..869045 Helicobacter pylori Shi470 6297510 YP_001910354.1 CDS murD NC_010698.2 869042 870310 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(869042..870310) Helicobacter pylori Shi470 6297508 YP_001910355.1 CDS mraY NC_010698.2 870312 871373 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(870312..871373) Helicobacter pylori Shi470 6297507 YP_001910356.1 CDS HPSH_04455 NC_010698.2 871498 872340 D hypothetical protein 871498..872340 Helicobacter pylori Shi470 6297506 YP_001910357.1 CDS rpmB NC_010698.2 872440 872628 D required for 70S ribosome assembly; 50S ribosomal protein L28 872440..872628 Helicobacter pylori Shi470 6297504 YP_001910358.1 CDS HPSH_04465 NC_010698.2 872778 873914 D COG1226 Kef-type K+ transport systems, predicted NAD-binding component; putative potassium channel protein 872778..873914 Helicobacter pylori Shi470 6297503 YP_001910359.1 CDS HPSH_04470 NC_010698.2 873916 874311 R COG0467 RecA-superfamily ATPases implicated in signal transduction; hypothetical protein complement(873916..874311) Helicobacter pylori Shi470 6297502 YP_001910360.1 CDS HPSH_04475 NC_010698.2 874327 874701 R hypothetical protein complement(874327..874701) Helicobacter pylori Shi470 6297501 YP_001910361.1 CDS HPSH_04480 NC_010698.2 874998 876074 D COG0582 Integrase; integrase/recombinase XerD 874998..876074 Helicobacter pylori Shi470 6296932 YP_001910362.1 CDS HPSH_04485 NC_010698.2 876139 877341 R hypothetical protein complement(876139..877341) Helicobacter pylori Shi470 6297498 YP_001910363.1 CDS HPSH_04490 NC_010698.2 877341 878726 R hypothetical protein complement(877341..878726) Helicobacter pylori Shi470 6297497 YP_001910364.1 CDS HPSH_04495 NC_010698.2 878730 880871 R hypothetical protein complement(878730..880871) Helicobacter pylori Shi470 6297496 YP_001910365.1 CDS HPSH_04500 NC_010698.2 880915 882183 R hypothetical protein complement(880915..882183) Helicobacter pylori Shi470 6297495 YP_001910366.1 CDS HPSH_04505 NC_010698.2 882184 883221 R hypothetical protein complement(882184..883221) Helicobacter pylori Shi470 6297494 YP_001910367.1 CDS HPSH_04510 NC_010698.2 883375 891786 D COG0827 Adenine-specific DNA methylase; hypothetical protein 883375..891786 Helicobacter pylori Shi470 6297493 YP_001910368.1 CDS HPSH_04515 NC_010698.2 892053 892709 D COG1192 ATPases involved in chromosome partitioning; PARA protein 892053..892709 Helicobacter pylori Shi470 6297492 YP_001910369.1 CDS HPSH_04520 NC_010698.2 892794 893063 D hypothetical protein 892794..893063 Helicobacter pylori Shi470 6297490 YP_001910370.1 CDS HPSH_04525 NC_010698.2 893095 894273 D hypothetical protein 893095..894273 Helicobacter pylori Shi470 6297489 YP_001910371.1 CDS HPSH_04530 NC_010698.2 894298 896205 R COG3843 Type IV secretory pathway, VirD2 components (relaxase); hypothetical protein complement(894298..896205) Helicobacter pylori Shi470 6297488 YP_001910372.1 CDS HPSH_04535 NC_010698.2 896499 896813 D hypothetical protein 896499..896813 Helicobacter pylori Shi470 6297486 YP_001910373.1 CDS HPSH_04540 NC_010698.2 896806 897087 D COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein 896806..897087 Helicobacter pylori Shi470 6297485 YP_001910374.1 CDS HPSH_04545 NC_010698.2 897362 899089 R COG3505 Type IV secretory pathway, VirD4 components; conjugal transfer protein TraG complement(897362..899089) Helicobacter pylori Shi470 6297483 YP_001910375.1 CDS HPSH_04550 NC_010698.2 899090 899647 R hypothetical protein complement(899090..899647) Helicobacter pylori Shi470 6297482 YP_001910376.1 CDS HPSH_04555 NC_010698.2 899648 899938 R hypothetical protein complement(899648..899938) Helicobacter pylori Shi470 6297481 YP_001910377.1 CDS HPSH_04560 NC_010698.2 899935 900390 R hypothetical protein complement(899935..900390) Helicobacter pylori Shi470 6297480 YP_001910378.1 CDS HPSH_04565 NC_010698.2 900387 901328 R COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; VirB11 type IV secretion ATPase complement(900387..901328) Helicobacter pylori Shi470 6297479 YP_001910379.1 CDS HPSH_04570 NC_010698.2 901328 901627 R hypothetical protein complement(901328..901627) Helicobacter pylori Shi470 6297476 YP_001910380.1 CDS HPSH_04575 NC_010698.2 901624 901887 R hypothetical protein complement(901624..901887) Helicobacter pylori Shi470 6297475 YP_001910381.1 CDS HPSH_04580 NC_010698.2 902009 902173 R hypothetical protein complement(902009..902173) Helicobacter pylori Shi470 6297420 YP_001910382.1 CDS HPSH_04585 NC_010698.2 902170 902256 R hypothetical protein complement(902170..902256) Helicobacter pylori Shi470 6297072 YP_001910383.1 CDS HPSH_04590 NC_010698.2 902243 903478 R COG2948 Type IV secretory pathway, VirB10 components; ComB3 protein complement(902243..903478) Helicobacter pylori Shi470 6296639 YP_001910384.1 CDS HPSH_04595 NC_010698.2 903475 905016 R COG3504 Type IV secretory pathway, VirB9 components; conjugal plasmid transfer system protein complement(903475..905016) Helicobacter pylori Shi470 6297473 YP_001910385.1 CDS HPSH_04600 NC_010698.2 905016 906002 R COG3736 Type IV secretory pathway, component VirB8; hypothetical protein complement(905016..906002) Helicobacter pylori Shi470 6297472 YP_001910386.1 CDS HPSH_04605 NC_010698.2 906004 906132 R hypothetical protein complement(906004..906132) Helicobacter pylori Shi470 6297471 YP_001910387.1 CDS HPSH_04610 NC_010698.2 906132 908066 R COG0550 Topoisomerase IA; topoisomerase I complement(906132..908066) Helicobacter pylori Shi470 6297470 YP_001910388.1 CDS HPSH_04615 NC_010698.2 908059 910557 R COG3451 Type IV secretory pathway, VirB4 components; DNA transfer protein complement(908059..910557) Helicobacter pylori Shi470 6297469 YP_001910389.1 CDS HPSH_04620 NC_010698.2 910570 910830 R hypothetical protein complement(910570..910830) Helicobacter pylori Shi470 6297468 YP_001910390.1 CDS HPSH_04625 NC_010698.2 910831 911133 R hypothetical protein complement(910831..911133) Helicobacter pylori Shi470 6297467 YP_001910391.1 CDS HPSH_04630 NC_010698.2 911123 911593 R hypothetical protein complement(911123..911593) Helicobacter pylori Shi470 6297466 YP_001910392.1 CDS HPSH_04635 NC_010698.2 911758 913038 R hypothetical protein complement(911758..913038) Helicobacter pylori Shi470 6297464 YP_001910393.1 CDS HPSH_04640 NC_010698.2 913049 913813 R hypothetical protein complement(913049..913813) Helicobacter pylori Shi470 6297463 YP_001910394.1 CDS HPSH_04645 NC_010698.2 913835 915454 R hypothetical protein complement(913835..915454) Helicobacter pylori Shi470 6297462 YP_001910395.1 CDS HPSH_04650 NC_010698.2 915459 915701 D hypothetical protein 915459..915701 Helicobacter pylori Shi470 6297461 YP_001910396.1 CDS ruvA NC_010698.2 915726 916277 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(915726..916277) Helicobacter pylori Shi470 6297460 YP_001910397.1 CDS HPSH_04660 NC_010698.2 916302 918146 R hypothetical protein complement(916302..918146) Helicobacter pylori Shi470 6297556 YP_001910398.1 CDS HPSH_04665 NC_010698.2 918239 919699 D COG0728 Uncharacterized membrane protein, putative virulence factor; virulence factor MviN 918239..919699 Helicobacter pylori Shi470 6297456 YP_001910399.1 CDS cysS NC_010698.2 919700 921097 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 919700..921097 Helicobacter pylori Shi470 6297455 YP_001910400.1 CDS HPSH_04675 NC_010698.2 921330 925193 D vacuolating cytotoxin A 921330..925193 Helicobacter pylori Shi470 6297454 YP_001910401.1 CDS HPSH_04680 NC_010698.2 925190 925345 R hypothetical protein complement(925190..925345) Helicobacter pylori Shi470 6297453 YP_001910402.1 CDS HPSH_04685 NC_010698.2 925497 926264 R COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron(III) dicitrate transporter, ATP-binding protein complement(925497..926264) Helicobacter pylori Shi470 6297452 YP_001910403.1 CDS HPSH_04690 NC_010698.2 926264 927244 R COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron(III dicitrate ABC transporter permease FecD complement(926264..927244) Helicobacter pylori Shi470 6297451 YP_001910404.1 CDS HPSH_04695 NC_010698.2 927237 928079 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain oxidoreductase complement(927237..928079) Helicobacter pylori Shi470 6297450 YP_001910405.1 CDS HPSH_04700 NC_010698.2 928220 928744 D COG1607 Acyl-CoA hydrolase; hypothetical protein 928220..928744 Helicobacter pylori Shi470 6297449 YP_001910406.1 CDS HPSH_04705 NC_010698.2 928847 929113 R COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein complement(928847..929113) Helicobacter pylori Shi470 6297448 YP_001910407.1 CDS HPSH_04710 NC_010698.2 929094 929471 R hypothetical protein complement(929094..929471) Helicobacter pylori Shi470 6297447 YP_001910408.1 CDS HPSH_04715 NC_010698.2 929531 929695 R hypothetical protein complement(929531..929695) Helicobacter pylori Shi470 6297446 YP_001910409.1 CDS HPSH_04720 NC_010698.2 929699 931930 R outer membrane protein BabA complement(929699..931930) Helicobacter pylori Shi470 6297444 YP_001910410.1 CDS HPSH_04725 NC_010698.2 931997 932125 D hypothetical protein 931997..932125 Helicobacter pylori Shi470 6297443 YP_001910411.1 CDS HPSH_04735 NC_010698.2 932848 933960 R COG0409 Hydrogenase maturation factor; hydrogenase expression/formation protein HypD complement(932848..933960) Helicobacter pylori Shi470 6297440 YP_001910412.1 CDS HPSH_04740 NC_010698.2 933979 934215 R COG0298 Hydrogenase maturation factor; hydrogenase expression/formation protein HypC complement(933979..934215) Helicobacter pylori Shi470 6297437 YP_001910413.1 CDS HPSH_04745 NC_010698.2 934215 934943 R COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; hydrogenase expression/formation protein HypB complement(934215..934943) Helicobacter pylori Shi470 6297294 YP_001910414.1 CDS HPSH_04750 NC_010698.2 934960 935064 R hypothetical protein complement(934960..935064) Helicobacter pylori Shi470 6297499 YP_001910415.1 CDS HPSH_04755 NC_010698.2 935204 935503 R COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein complement(935204..935503) Helicobacter pylori Shi470 6296371 YP_001910416.1 CDS HPSH_04760 NC_010698.2 935514 936719 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(935514..936719) Helicobacter pylori Shi470 6297435 YP_001910417.1 CDS HPSH_04765 NC_010698.2 936737 938293 R COG0280 Phosphotransacetylase; phosphotransacetylase complement(936737..938293) Helicobacter pylori Shi470 6297434 YP_001910418.1 CDS HPSH_04770 NC_010698.2 938515 940074 D hypothetical protein 938515..940074 Helicobacter pylori Shi470 6297433 YP_001910419.1 CDS flgD NC_010698.2 940125 941099 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 940125..941099 Helicobacter pylori Shi470 6297432 YP_001910420.1 CDS flgE NC_010698.2 941096 942913 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 941096..942913 Helicobacter pylori Shi470 6297431 YP_001910421.1 CDS HPSH_04785 NC_010698.2 942972 943607 D putative restriction endonuclease 942972..943607 Helicobacter pylori Shi470 6297430 YP_001910422.1 CDS HPSH_04790 NC_010698.2 943588 944736 D COG0827 Adenine-specific DNA methylase; type II DNA modification methyltransferase 943588..944736 Helicobacter pylori Shi470 6297429 YP_001910423.1 CDS HPSH_04795 NC_010698.2 944730 946760 D COG0210 Superfamily I DNA and RNA helicases; rep helicase, single-stranded DNA-dependent ATPase 944730..946760 Helicobacter pylori Shi470 6297428 YP_001910424.1 CDS HPSH_04800 NC_010698.2 947076 947177 D hypothetical protein 947076..947177 Helicobacter pylori Shi470 6297427 YP_001910425.1 CDS HPSH_04805 NC_010698.2 947287 948855 D outer membrane protein HopC 947287..948855 Helicobacter pylori Shi470 6297425 YP_001910426.1 CDS HPSH_04810 NC_010698.2 948877 950457 D outer membrane protein HopB 948877..950457 Helicobacter pylori Shi470 6297424 YP_001910427.1 CDS HPSH_04815 NC_010698.2 950601 950672 R hypothetical protein complement(950601..950672) Helicobacter pylori Shi470 6297423 YP_001910428.1 CDS HPSH_04830 NC_010698.2 952775 955216 R COG1629 Outer membrane receptor proteins, mostly Fe transport; iron-regulated outer membrane protein complement(952775..955216) Helicobacter pylori Shi470 6297422 YP_001910429.1 CDS HPSH_04835 NC_010698.2 955391 955822 R hypothetical protein complement(955391..955822) Helicobacter pylori Shi470 6297421 YP_001910430.1 CDS carB NC_010698.2 955827 959084 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(955827..959084) Helicobacter pylori Shi470 6297474 YP_001910431.1 CDS HPSH_04845 NC_010698.2 959179 959871 R COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein complement(959179..959871) Helicobacter pylori Shi470 6297417 YP_001910432.1 CDS HPSH_04850 NC_010698.2 960014 961009 D COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 960014..961009 Helicobacter pylori Shi470 6297416 YP_001910433.1 CDS HPSH_04865 NC_010698.2 968318 969421 D outer membrane protein 968318..969421 Helicobacter pylori Shi470 6297415 YP_001910434.1 CDS HPSH_04870 NC_010698.2 969478 969684 R COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; 4-oxalocrotonate tautomerase complement(969478..969684) Helicobacter pylori Shi470 6297414 YP_001910435.1 CDS recR NC_010698.2 969830 970411 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 969830..970411 Helicobacter pylori Shi470 6297413 YP_001910436.1 CDS truD NC_010698.2 970408 971553 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 970408..971553 Helicobacter pylori Shi470 6297412 YP_001910437.1 CDS HPSH_04885 NC_010698.2 971540 972472 D putative metalloprotease; heat shock protein HtpX 971540..972472 Helicobacter pylori Shi470 6297411 YP_001910438.1 CDS folE NC_010698.2 972473 973015 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 972473..973015 Helicobacter pylori Shi470 6297410 YP_001910439.1 CDS HPSH_04895 NC_010698.2 973031 973942 D COG0142 Geranylgeranyl pyrophosphate synthase; geranyltranstransferase 973031..973942 Helicobacter pylori Shi470 6297408 YP_001910440.1 CDS surE NC_010698.2 973939 974742 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 973939..974742 Helicobacter pylori Shi470 6297407 YP_001910441.1 CDS HPSH_04905 NC_010698.2 974739 975398 D hypothetical protein 974739..975398 Helicobacter pylori Shi470 6297406 YP_001910442.1 CDS HPSH_04910 NC_010698.2 975402 976004 D COG0720 6-pyruvoyl-tetrahydropterin synthase; hypothetical protein 975402..976004 Helicobacter pylori Shi470 6297403 YP_001910443.1 CDS HPSH_04915 NC_010698.2 976001 976756 D COG0602 Organic radical activating enzymes; hypothetical protein 976001..976756 Helicobacter pylori Shi470 6297402 YP_001910444.1 CDS HPSH_04920 NC_010698.2 976767 977252 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 976767..977252 Helicobacter pylori Shi470 6297401 YP_001910445.1 CDS HPSH_04925 NC_010698.2 977473 979458 D putative outer membrane protein HomB 977473..979458 Helicobacter pylori Shi470 6297400 YP_001910446.1 CDS HPSH_04930 NC_010698.2 979596 980765 R COG0477 Permeases of the major facilitator superfamily; proline and betaine transporter complement(979596..980765) Helicobacter pylori Shi470 6297399 YP_001910447.1 CDS HPSH_04935 NC_010698.2 981198 981407 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(981198..981407) Helicobacter pylori Shi470 6297398 YP_001910448.1 CDS HPSH_04940 NC_010698.2 981475 982197 R COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(981475..982197) Helicobacter pylori Shi470 6297397 YP_001910449.1 CDS HPSH_04945 NC_010698.2 982172 982948 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; polar amino acid ABC transporter periplasmic protein complement(982172..982948) Helicobacter pylori Shi470 6297381 YP_001910451.1 CDS HPSH_04955 NC_010698.2 983017 984150 R COG0787 Alanine racemase; alanine racemase complement(983017..984150) Helicobacter pylori Shi470 6296338 YP_001910452.1 CDS HPSH_04960 NC_010698.2 984157 985509 R COG1115 Na+/alanine symporter; D-alanine glycine permease complement(984157..985509) Helicobacter pylori Shi470 6297395 YP_001910453.1 CDS HPSH_04965 NC_010698.2 985550 986782 R COG0665 Glycine/D-amino acid oxidases (deaminating); D-Amino acid dehydrogenase complement(985550..986782) Helicobacter pylori Shi470 6297394 YP_001910454.1 CDS HPSH_04970 NC_010698.2 986805 987182 R COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein complement(986805..987182) Helicobacter pylori Shi470 6297392 YP_001910455.1 CDS HPSH_04975 NC_010698.2 987594 987890 R hypothetical protein complement(987594..987890) Helicobacter pylori Shi470 6297390 YP_001910456.1 CDS HPSH_04990 NC_010698.2 990240 990635 D hypothetical protein 990240..990635 Helicobacter pylori Shi470 6297385 YP_001910457.1 CDS HPSH_04995 NC_010698.2 991213 992226 R hypothetical protein complement(991213..992226) Helicobacter pylori Shi470 6297383 YP_001910458.1 CDS HPSH_05000 NC_010698.2 992236 992688 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(992236..992688) Helicobacter pylori Shi470 6297396 YP_001910459.1 CDS HPSH_05005 NC_010698.2 992702 993571 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(992702..993571) Helicobacter pylori Shi470 6297379 YP_001910460.1 CDS HPSH_05010 NC_010698.2 993652 994266 D COG0540 Aspartate carbamoyltransferase, catalytic chain; putative recombination protein RecO 993652..994266 Helicobacter pylori Shi470 6297378 YP_001910461.1 CDS HPSH_05015 NC_010698.2 994277 994933 D COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein 994277..994933 Helicobacter pylori Shi470 6297377 YP_001910462.1 CDS HPSH_05020 NC_010698.2 994936 995502 R hypothetical protein complement(994936..995502) Helicobacter pylori Shi470 6297376 YP_001910463.1 CDS HPSH_05035 NC_010698.2 996196 997050 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(996196..997050) Helicobacter pylori Shi470 6297373 YP_001910464.1 CDS HPSH_05040 NC_010698.2 997060 997788 R COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein complement(997060..997788) Helicobacter pylori Shi470 6297372 YP_001910465.1 CDS HPSH_05045 NC_010698.2 997806 998987 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(997806..998987) Helicobacter pylori Shi470 6297371 YP_001910466.1 CDS HPSH_05050 NC_010698.2 998988 999752 R COG1579 Zn-ribbon protein, possibly nucleic acid-binding; hypothetical protein complement(998988..999752) Helicobacter pylori Shi470 6297369 YP_001910467.1 CDS HPSH_05055 NC_010698.2 999762 1000493 R COG0327 Uncharacterized conserved protein; hypothetical protein complement(999762..1000493) Helicobacter pylori Shi470 6297368 YP_001910468.1 CDS glyQ NC_010698.2 1000495 1001391 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1000495..1001391) Helicobacter pylori Shi470 6297367 YP_001910469.1 CDS gpsA NC_010698.2 1001405 1002343 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(1001405..1002343) Helicobacter pylori Shi470 6297365 YP_001910470.1 CDS HPSH_05070 NC_010698.2 1002373 1002522 R hypothetical protein complement(1002373..1002522) Helicobacter pylori Shi470 6297364 YP_001910471.1 CDS HPSH_05085 NC_010698.2 1003750 1006050 R COG0699 Predicted GTPases (dynamin-related); hypothetical protein complement(1003750..1006050) Helicobacter pylori Shi470 6297363 YP_001910472.1 CDS HPSH_05105 NC_010698.2 1007543 1007695 R hypothetical protein complement(1007543..1007695) Helicobacter pylori Shi470 6297362 YP_001910473.1 CDS HPSH_05110 NC_010698.2 1007902 1008189 R COG3309 Uncharacterized virulence-associated protein D; virulence associated protein D complement(1007902..1008189) Helicobacter pylori Shi470 6297361 YP_001910474.1 CDS HPSH_05115 NC_010698.2 1008257 1008538 R hypothetical protein complement(1008257..1008538) Helicobacter pylori Shi470 6297360 YP_001910475.1 CDS HPSH_05120 NC_010698.2 1008549 1011608 R COG3696 Putative silver efflux pump; putative cation efflux system protein complement(1008549..1011608) Helicobacter pylori Shi470 6297359 YP_001910476.1 CDS HPSH_05125 NC_010698.2 1011608 1012687 R COG0845 Membrane-fusion protein; cobalt-zinc-cadmium resistance protein complement(1011608..1012687) Helicobacter pylori Shi470 6297358 YP_001910477.1 CDS HPSH_05130 NC_010698.2 1012684 1014009 R hypothetical protein complement(1012684..1014009) Helicobacter pylori Shi470 6297357 YP_001910478.1 CDS glyS NC_010698.2 1013981 1016083 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1013981..1016083) Helicobacter pylori Shi470 6297245 YP_001910479.1 CDS HPSH_05140 NC_010698.2 1016195 1017262 D hypothetical protein 1016195..1017262 Helicobacter pylori Shi470 6297457 YP_001910480.1 CDS HPSH_05145 NC_010698.2 1017275 1018750 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1017275..1018750 Helicobacter pylori Shi470 6296423 YP_001910481.1 CDS gatC NC_010698.2 1018765 1019046 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1018765..1019046 Helicobacter pylori Shi470 6297354 YP_001910482.1 CDS HPSH_05155 NC_010698.2 1019119 1020429 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(1019119..1020429) Helicobacter pylori Shi470 6297353 YP_001910483.1 CDS HPSH_05160 NC_010698.2 1020469 1022022 D COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein 1020469..1022022 Helicobacter pylori Shi470 6297352 YP_001910484.1 CDS HPSH_05165 NC_010698.2 1022037 1023518 D COG0849 Actin-like ATPase involved in cell division; cell division protein 1022037..1023518 Helicobacter pylori Shi470 6297350 YP_001910485.1 CDS HPSH_05170 NC_010698.2 1023653 1024801 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1023653..1024801 Helicobacter pylori Shi470 6297349 YP_001910486.1 CDS HPSH_05175 NC_010698.2 1024868 1024975 R hypothetical protein complement(1024868..1024975) Helicobacter pylori Shi470 6297348 YP_001910487.1 CDS HPSH_05200 NC_010698.2 1026463 1027287 R COG0668 Small-conductance mechanosensitive channel; hypothetical protein complement(1026463..1027287) Helicobacter pylori Shi470 6297347 YP_001910488.1 CDS HPSH_05205 NC_010698.2 1027300 1027479 R hypothetical protein complement(1027300..1027479) Helicobacter pylori Shi470 6297346 YP_001910489.1 CDS xseA NC_010698.2 1027745 1028107 R COG1570 Exonuclease VII, large subunit; exodeoxyribonuclease VII large subunit complement(1027745..1028107) Helicobacter pylori Shi470 6297344 YP_001910490.1 CDS HPSH_05215 NC_010698.2 1028113 1028193 R hypothetical protein complement(1028113..1028193) Helicobacter pylori Shi470 6297343 YP_001910491.1 CDS HPSH_05220 NC_010698.2 1028402 1029136 R hypothetical protein complement(1028402..1029136) Helicobacter pylori Shi470 6297342 YP_001910492.1 CDS HPSH_05225 NC_010698.2 1029146 1029367 R hypothetical protein complement(1029146..1029367) Helicobacter pylori Shi470 6297341 YP_001910493.1 CDS HPSH_05230 NC_010698.2 1029367 1029702 R hypothetical protein complement(1029367..1029702) Helicobacter pylori Shi470 6297340 YP_001910494.1 CDS HPSH_05235 NC_010698.2 1029689 1030114 R COG0343 Queuine/archaeosine tRNA-ribosyltransferase; hypothetical protein complement(1029689..1030114) Helicobacter pylori Shi470 6297517 YP_001910495.1 CDS HPSH_05240 NC_010698.2 1030253 1030675 R hypothetical protein complement(1030253..1030675) Helicobacter pylori Shi470 6297336 YP_001910496.1 CDS HPSH_05245 NC_010698.2 1030685 1030963 R hypothetical protein complement(1030685..1030963) Helicobacter pylori Shi470 6297335 YP_001910497.1 CDS HPSH_05250 NC_010698.2 1030976 1031629 R COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; phage/colicin/tellurite resistance cluster terY protein complement(1030976..1031629) Helicobacter pylori Shi470 6297334 YP_001910498.1 CDS HPSH_05255 NC_010698.2 1036094 1036360 R hypothetical protein complement(1036094..1036360) Helicobacter pylori Shi470 6297330 YP_001910499.1 CDS HPSH_05260 NC_010698.2 1036552 1038303 D COG1479 Uncharacterized conserved protein; hypothetical protein 1036552..1038303 Helicobacter pylori Shi470 6297329 YP_001910500.1 CDS HPSH_05290 NC_010698.2 1041604 1042443 D hypothetical protein 1041604..1042443 Helicobacter pylori Shi470 6297328 YP_001910501.1 CDS HPSH_05295 NC_010698.2 1042450 1042539 D hypothetical protein 1042450..1042539 Helicobacter pylori Shi470 6297327 YP_001910502.1 CDS HPSH_05300 NC_010698.2 1042645 1044492 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(1042645..1044492) Helicobacter pylori Shi470 6297326 YP_001910503.1 CDS HPSH_05305 NC_010698.2 1044507 1045676 R COG0438 Glycosyltransferase; type 1 capsular polysaccharide biosynthesis protein J complement(1044507..1045676) Helicobacter pylori Shi470 6297322 YP_001910504.1 CDS HPSH_05310 NC_010698.2 1045680 1046108 R COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein complement(1045680..1046108) Helicobacter pylori Shi470 6297321 YP_001910505.1 CDS HPSH_05315 NC_010698.2 1046124 1046909 R COG0500 SAM-dependent methyltransferases; hypothetical protein complement(1046124..1046909) Helicobacter pylori Shi470 6297319 YP_001910506.1 CDS HPSH_05320 NC_010698.2 1046913 1047920 R hypothetical protein complement(1046913..1047920) Helicobacter pylori Shi470 6297318 YP_001910507.1 CDS HPSH_05325 NC_010698.2 1047921 1049909 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1047921..1049909) Helicobacter pylori Shi470 6297317 YP_001910508.1 CDS HPSH_05330 NC_010698.2 1050079 1051248 D COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane fatty acid synthase 1050079..1051248 Helicobacter pylori Shi470 6297315 YP_001910509.1 CDS HPSH_05335 NC_010698.2 1051251 1053122 R COG0668 Small-conductance mechanosensitive channel; hypothetical protein complement(1051251..1053122) Helicobacter pylori Shi470 6297095 YP_001910510.1 CDS HPSH_05345 NC_010698.2 1054042 1054143 R hypothetical protein complement(1054042..1054143) Helicobacter pylori Shi470 6297306 YP_001910511.1 CDS HPSH_05350 NC_010698.2 1054236 1055018 R hypothetical protein complement(1054236..1055018) Helicobacter pylori Shi470 6297304 YP_001910512.1 CDS HPSH_05355 NC_010698.2 1055015 1055080 R hypothetical protein complement(1055015..1055080) Helicobacter pylori Shi470 6297303 YP_001910513.1 CDS guaA NC_010698.2 1055071 1056597 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1055071..1056597) Helicobacter pylori Shi470 6297302 YP_001910514.1 CDS HPSH_05365 NC_010698.2 1056608 1057096 R hypothetical protein complement(1056608..1057096) Helicobacter pylori Shi470 6297301 YP_001910515.1 CDS HPSH_05370 NC_010698.2 1057257 1059647 R COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; biotin sulfoxide reductase BisC complement(1057257..1059647) Helicobacter pylori Shi470 6297300 YP_001910516.1 CDS HPSH_05375 NC_010698.2 1059747 1060337 R hypothetical protein complement(1059747..1060337) Helicobacter pylori Shi470 6297299 YP_001910517.1 CDS HPSH_05380 NC_010698.2 1060363 1061685 R COG0520 Selenocysteine lyase; nifS-like protein complement(1060363..1061685) Helicobacter pylori Shi470 6297296 YP_001910518.1 CDS HPSH_05385 NC_010698.2 1061704 1062018 R COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; protein kinase C inhibitor complement(1061704..1062018) Helicobacter pylori Shi470 6297295 YP_001910519.1 CDS pheS NC_010698.2 1062099 1063085 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1062099..1063085 Helicobacter pylori Shi470 6297436 YP_001910520.1 CDS pheT NC_010698.2 1063085 1065379 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1063085..1065379 Helicobacter pylori Shi470 6297292 YP_001910521.1 CDS HPSH_05400 NC_010698.2 1065395 1066684 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1065395..1066684 Helicobacter pylori Shi470 6297291 YP_001910522.1 CDS ispH NC_010698.2 1066674 1067498 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1066674..1067498 Helicobacter pylori Shi470 6297290 YP_001910523.1 CDS rpsA NC_010698.2 1067619 1069277 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1067619..1069277 Helicobacter pylori Shi470 6297287 YP_001910524.1 CDS HPSH_05415 NC_010698.2 1069306 1069650 D hypothetical protein 1069306..1069650 Helicobacter pylori Shi470 6297286 YP_001910525.1 CDS HPSH_05420 NC_010698.2 1069839 1071413 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1069839..1071413 Helicobacter pylori Shi470 6297284 YP_001910526.1 CDS HPSH_05425 NC_010698.2 1071423 1073273 D COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; hypothetical protein 1071423..1073273 Helicobacter pylori Shi470 6297283 YP_001910527.1 CDS HPSH_05430 NC_010698.2 1073283 1073951 D COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein 1073283..1073951 Helicobacter pylori Shi470 6297282 YP_001910528.1 CDS HPSH_05435 NC_010698.2 1073953 1074711 D COG2908 Uncharacterized protein conserved in bacteria; hypothetical protein 1073953..1074711 Helicobacter pylori Shi470 6297281 YP_001910529.1 CDS HPSH_05440 NC_010698.2 1074715 1075650 D COG0835 Chemotaxis signal transduction protein; CheA-MCP interaction modulator 1074715..1075650 Helicobacter pylori Shi470 6297279 YP_001910530.1 CDS HPSH_05445 NC_010698.2 1075708 1078152 D COG0643 Chemotaxis protein histidine kinase and related kinases; autophosphorylating histidine kinase 1075708..1078152 Helicobacter pylori Shi470 6297278 YP_001910531.1 CDS HPSH_05450 NC_010698.2 1078149 1078646 D COG0835 Chemotaxis signal transduction protein; purine-binding chemotaxis protein CheW 1078149..1078646 Helicobacter pylori Shi470 6297276 YP_001910532.1 CDS HPSH_05455 NC_010698.2 1078910 1079410 R COG2077 Peroxiredoxin; thiol peroxidase complement(1078910..1079410) Helicobacter pylori Shi470 6297273 YP_001910533.1 CDS HPSH_05460 NC_010698.2 1079634 1080275 D COG0605 Superoxide dismutase; iron-dependent superoxide dismutase 1079634..1080275 Helicobacter pylori Shi470 6297270 YP_001910534.1 CDS HPSH_05465 NC_010698.2 1080327 1081046 D COG0500 SAM-dependent methyltransferases; hypothetical protein 1080327..1081046 Helicobacter pylori Shi470 6297269 YP_001910535.1 CDS HPSH_05470 NC_010698.2 1081074 1082933 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1081074..1082933) Helicobacter pylori Shi470 6297268 YP_001910536.1 CDS HPSH_05475 NC_010698.2 1082918 1083154 R hypothetical protein complement(1082918..1083154) Helicobacter pylori Shi470 6297267 YP_001910537.1 CDS HPSH_05480 NC_010698.2 1083167 1083394 R COG0055 F0F1-type ATP synthase, beta subunit; hypothetical protein complement(1083167..1083394) Helicobacter pylori Shi470 6297266 YP_001910538.1 CDS HPSH_05485 NC_010698.2 1083597 1084343 D hypothetical protein 1083597..1084343 Helicobacter pylori Shi470 6297200 YP_001910539.1 CDS HPSH_05490 NC_010698.2 1084351 1084878 R hypothetical protein complement(1084351..1084878) Helicobacter pylori Shi470 6297418 YP_001910540.1 CDS HPSH_05495 NC_010698.2 1084844 1084981 D hypothetical protein 1084844..1084981 Helicobacter pylori Shi470 6296116 YP_001910541.1 CDS HPSH_05510 NC_010698.2 1086271 1087101 D COG2890 Methylase of polypeptide chain release factors; protoporphyrinogen oxidase HemK 1086271..1087101 Helicobacter pylori Shi470 6297262 YP_001910542.1 CDS HPSH_05515 NC_010698.2 1087168 1088514 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1087168..1088514 Helicobacter pylori Shi470 6297261 YP_001910543.1 CDS HPSH_05520 NC_010698.2 1088529 1089890 R alpha-(1,3)-fucosyltransferase complement(1088529..1089890) Helicobacter pylori Shi470 6297259 YP_001910544.1 CDS HPSH_05525 NC_010698.2 1089900 1092710 R COG1333 ResB protein required for cytochrome c biosynthesis; cytochrome c-type biogenesis protein complement(1089900..1092710) Helicobacter pylori Shi470 6297258 YP_001910545.1 CDS HPSH_05530 NC_010698.2 1092719 1093390 R COG2143 Thioredoxin-related protein; hypothetical protein complement(1092719..1093390) Helicobacter pylori Shi470 6297257 YP_001910546.1 CDS hemH NC_010698.2 1093463 1094470 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1093463..1094470) Helicobacter pylori Shi470 6297256 YP_001910547.1 CDS HPSH_05540 NC_010698.2 1094526 1094957 D hypothetical protein 1094526..1094957 Helicobacter pylori Shi470 6297255 YP_001910548.1 CDS HPSH_05545 NC_010698.2 1094958 1095638 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1094958..1095638 Helicobacter pylori Shi470 6297253 YP_001910549.1 CDS HPSH_05550 NC_010698.2 1095662 1097890 R putative outer membrane protein complement(1095662..1097890) Helicobacter pylori Shi470 6297252 YP_001910550.1 CDS dcd NC_010698.2 1098049 1098615 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(1098049..1098615) Helicobacter pylori Shi470 6297251 YP_001910551.1 CDS HPSH_05560 NC_010698.2 1098745 1099215 D COG0511 Biotin carboxyl carrier protein; biotin carboxyl carrier protein FabE 1098745..1099215 Helicobacter pylori Shi470 6297249 YP_001910552.1 CDS HPSH_05565 NC_010698.2 1099221 1100588 D biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1099221..1100588 Helicobacter pylori Shi470 6297248 YP_001910553.1 CDS HPSH_05570 NC_010698.2 1100681 1101643 D putative type II DNA modification enzyme methyltransferase 1100681..1101643 Helicobacter pylori Shi470 6297247 YP_001910554.1 CDS HPSH_05575 NC_010698.2 1101643 1102191 D hypothetical protein 1101643..1102191 Helicobacter pylori Shi470 6297246 YP_001910555.1 CDS HPSH_05580 NC_010698.2 1102240 1102884 D hypothetical protein 1102240..1102884 Helicobacter pylori Shi470 6297356 YP_001910556.1 CDS HPSH_05585 NC_010698.2 1102881 1104008 D COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; spore coat polysaccharide biosynthesis protein C 1102881..1104008 Helicobacter pylori Shi470 6297243 YP_001910557.1 CDS nrdF NC_010698.2 1104330 1105355 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1104330..1105355 Helicobacter pylori Shi470 6297239 YP_001910558.1 CDS pcm NC_010698.2 1105365 1105994 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1105365..1105994 Helicobacter pylori Shi470 6297238 YP_001910559.1 CDS HPSH_05605 NC_010698.2 1106005 1107042 D COG0795 Predicted permeases; hypothetical protein 1106005..1107042 Helicobacter pylori Shi470 6297237 YP_001910560.1 CDS truA NC_010698.2 1107043 1107771 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1107043..1107771 Helicobacter pylori Shi470 6297235 YP_001910561.1 CDS HPSH_05615 NC_010698.2 1107765 1108799 R COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase complement(1107765..1108799) Helicobacter pylori Shi470 6297234 YP_001910562.1 CDS HPSH_05630 NC_010698.2 1109329 1110864 D putative outer membrane protein 1109329..1110864 Helicobacter pylori Shi470 6297228 YP_001910563.1 CDS HPSH_05635 NC_010698.2 1110886 1111638 D COG4221 Short-chain alcohol dehydrogenase of unknown specificity; short chain alcohol dehydrogenase 1110886..1111638 Helicobacter pylori Shi470 6297227 YP_001910564.1 CDS HPSH_05640 NC_010698.2 1111825 1112697 R COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein complement(1111825..1112697) Helicobacter pylori Shi470 6297226 YP_001910565.1 CDS HPSH_05645 NC_010698.2 1112767 1113393 R COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase complement(1112767..1113393) Helicobacter pylori Shi470 6297224 YP_001910566.1 CDS HPSH_05650 NC_010698.2 1113412 1115238 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1113412..1115238) Helicobacter pylori Shi470 6297223 YP_001910567.1 CDS HPSH_05655 NC_010698.2 1115304 1116581 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1115304..1116581 Helicobacter pylori Shi470 6297222 YP_001910568.1 CDS HPSH_05660 NC_010698.2 1116592 1117275 D COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; glucose-6-phosphate 1-dehydrogenase DevB 1116592..1117275 Helicobacter pylori Shi470 6297045 YP_001910569.1 CDS glk NC_010698.2 1117262 1118272 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1117262..1118272 Helicobacter pylori Shi470 6297293 YP_001910570.1 CDS HPSH_05670 NC_010698.2 1118434 1119486 D COG1064 Zn-dependent alcohol dehydrogenases; NADP-dependent alcohol dehydrogenase 1118434..1119486 Helicobacter pylori Shi470 6297419 YP_001910571.1 CDS HPSH_05675 NC_010698.2 1119498 1120658 R COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; putative lipopolysaccharide biosynthesis protein complement(1119498..1120658) Helicobacter pylori Shi470 6297221 YP_001910572.1 CDS HPSH_05680 NC_010698.2 1120791 1121981 R COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; putative lipopolysaccharide biosynthesis protein complement(1120791..1121981) Helicobacter pylori Shi470 6297220 YP_001910573.1 CDS HPSH_05685 NC_010698.2 1122161 1123468 D hypothetical protein 1122161..1123468 Helicobacter pylori Shi470 6297219 YP_001910574.1 CDS HPSH_05690 NC_010698.2 1123475 1124146 R outer membrane protein complement(1123475..1124146) Helicobacter pylori Shi470 6297218 YP_001910575.1 CDS HPSH_05695 NC_010698.2 1124436 1124996 D COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; pyruvate flavodoxin oxidoreductase subunit gamma 1124436..1124996 Helicobacter pylori Shi470 6297217 YP_001910576.1 CDS porD NC_010698.2 1125012 1125404 D COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit; pyruvate flavodoxin oxidoreductase subunit delta 1125012..1125404 Helicobacter pylori Shi470 6297214 YP_001910577.1 CDS porA NC_010698.2 1125414 1126637 D COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; pyruvate flavodoxin oxidoreductase subunit alpha 1125414..1126637 Helicobacter pylori Shi470 6297213 YP_001910578.1 CDS HPSH_05710 NC_010698.2 1126650 1127594 D COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; pyruvate ferredoxin oxidoreductase subunit beta 1126650..1127594 Helicobacter pylori Shi470 6297212 YP_001910579.1 CDS HPSH_05715 NC_010698.2 1127704 1129026 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1127704..1129026 Helicobacter pylori Shi470 6297211 YP_001910580.1 CDS HPSH_05720 NC_010698.2 1129095 1129928 D outer membrane protein Horl 1129095..1129928 Helicobacter pylori Shi470 6297210 YP_001910581.1 CDS HPSH_05725 NC_010698.2 1129925 1131901 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1129925..1131901) Helicobacter pylori Shi470 6297209 YP_001910582.1 CDS HPSH_05730 NC_010698.2 1132042 1132425 R hypothetical protein complement(1132042..1132425) Helicobacter pylori Shi470 6297205 YP_001910583.1 CDS HPSH_05735 NC_010698.2 1132422 1133630 R hypothetical protein complement(1132422..1133630) Helicobacter pylori Shi470 6297204 YP_001910584.1 CDS HPSH_05740 NC_010698.2 1133983 1134060 R hypothetical protein complement(1133983..1134060) Helicobacter pylori Shi470 6297203 YP_001910585.1 CDS HPSH_05745 NC_010698.2 1134057 1134827 R COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein X complement(1134057..1134827) Helicobacter pylori Shi470 6297202 YP_001910586.1 CDS HPSH_05750 NC_010698.2 1134830 1134919 R hypothetical protein complement(1134830..1134919) Helicobacter pylori Shi470 6297265 YP_001910587.1 CDS HPSH_05755 NC_010698.2 1135096 1136799 R COG0405 Gamma-glutamyltransferase; gamma-glutamyltranspeptidase complement(1135096..1136799) Helicobacter pylori Shi470 6297198 YP_001910588.1 CDS flgK NC_010698.2 1137004 1138824 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(1137004..1138824) Helicobacter pylori Shi470 6297197 YP_001910589.1 CDS HPSH_05765 NC_010698.2 1138826 1139260 R hypothetical protein complement(1138826..1139260) Helicobacter pylori Shi470 6297196 YP_001910590.1 CDS HPSH_05770 NC_010698.2 1139390 1140352 R COG0270 Site-specific DNA methylase; type II DNA modification methyltransferase complement(1139390..1140352) Helicobacter pylori Shi470 6297195 YP_001910591.1 CDS HPSH_05775 NC_010698.2 1140373 1140462 D hypothetical protein 1140373..1140462 Helicobacter pylori Shi470 6297193 YP_001910592.1 CDS HPSH_05780 NC_010698.2 1140483 1140686 R flgM protein complement(1140483..1140686) Helicobacter pylori Shi470 6297192 YP_001910593.1 CDS HPSH_05785 NC_010698.2 1140750 1140956 R hypothetical protein complement(1140750..1140956) Helicobacter pylori Shi470 6297191 YP_001910594.1 CDS HPSH_05790 NC_010698.2 1140988 1141536 R COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; peptidyl-prolyl cis-trans isomerase complement(1140988..1141536) Helicobacter pylori Shi470 6297190 YP_001910595.1 CDS HPSH_05795 NC_010698.2 1141523 1142518 R hypothetical protein complement(1141523..1142518) Helicobacter pylori Shi470 6297189 YP_001910596.1 CDS HPSH_05800 NC_010698.2 1142526 1143077 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated lipoprotein complement(1142526..1143077) Helicobacter pylori Shi470 6297188 YP_001910597.1 CDS tolB NC_010698.2 1143144 1144397 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(1143144..1144397) Helicobacter pylori Shi470 6297187 YP_001910598.1 CDS HPSH_05810 NC_010698.2 1144394 1145206 R hypothetical protein complement(1144394..1145206) Helicobacter pylori Shi470 6297185 YP_001910599.1 CDS HPSH_05815 NC_010698.2 1145225 1145626 R COG0848 Biopolymer transport protein; biopolymer transport protein complement(1145225..1145626) Helicobacter pylori Shi470 6297182 YP_001910600.1 CDS HPSH_05820 NC_010698.2 1145679 1146248 R COG0811 Biopolymer transport proteins; biopolymer transport protein complement(1145679..1146248) Helicobacter pylori Shi470 6297181 YP_001910601.1 CDS atpC NC_010698.2 1146259 1146630 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1146259..1146630) Helicobacter pylori Shi470 6297180 YP_001910602.1 CDS HPSH_05830 NC_010698.2 1146641 1148050 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1146641..1148050) Helicobacter pylori Shi470 6297178 YP_001910603.1 CDS HPSH_05835 NC_010698.2 1148070 1148975 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1148070..1148975) Helicobacter pylori Shi470 6297177 YP_001910604.1 CDS HPSH_05840 NC_010698.2 1148990 1150501 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1148990..1150501) Helicobacter pylori Shi470 6297147 YP_001910605.1 CDS HPSH_05845 NC_010698.2 1150524 1151066 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1150524..1151066) Helicobacter pylori Shi470 6297380 YP_001910606.1 CDS HPSH_05850 NC_010698.2 1151067 1151582 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1151067..1151582) Helicobacter pylori Shi470 6296425 YP_001910607.1 CDS HPSH_05855 NC_010698.2 1151586 1152020 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' complement(1151586..1152020) Helicobacter pylori Shi470 6297174 YP_001910608.1 CDS HPSH_05860 NC_010698.2 1152131 1153003 R COG1475 Predicted transcriptional regulators; plasmid replication-partition-like protein complement(1152131..1153003) Helicobacter pylori Shi470 6297173 YP_001910609.1 CDS HPSH_05865 NC_010698.2 1153006 1153803 R COG1192 ATPases involved in chromosome partitioning; SpoOJ regulator (soj) complement(1153006..1153803) Helicobacter pylori Shi470 6297172 YP_001910610.1 CDS HPSH_05870 NC_010698.2 1153806 1154444 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(1153806..1154444) Helicobacter pylori Shi470 6297170 YP_001910611.1 CDS fmt NC_010698.2 1154441 1155337 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1154441..1155337) Helicobacter pylori Shi470 6297169 YP_001910612.1 CDS HPSH_05890 NC_010698.2 1157863 1159161 R COG4487 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1157863..1159161) Helicobacter pylori Shi470 6297168 YP_001910613.1 CDS HPSH_05895 NC_010698.2 1159424 1159531 D hypothetical protein 1159424..1159531 Helicobacter pylori Shi470 6297166 YP_001910614.1 CDS HPSH_05900 NC_010698.2 1159918 1160013 R hypothetical protein complement(1159918..1160013) Helicobacter pylori Shi470 6297165 YP_001910615.1 CDS HPSH_05905 NC_010698.2 1162228 1162320 D hypothetical protein 1162228..1162320 Helicobacter pylori Shi470 6297159 YP_001910616.1 CDS HPSH_05910 NC_010698.2 1162317 1163117 R COG1432 Uncharacterized conserved protein; hypothetical protein complement(1162317..1163117) Helicobacter pylori Shi470 6297154 YP_001910617.1 CDS HPSH_05915 NC_010698.2 1163177 1163266 D hypothetical protein 1163177..1163266 Helicobacter pylori Shi470 6297153 YP_001910618.1 CDS rplS NC_010698.2 1163421 1163777 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1163421..1163777) Helicobacter pylori Shi470 6297150 YP_001910619.1 CDS trmD NC_010698.2 1163799 1164488 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1163799..1164488) Helicobacter pylori Shi470 6297148 YP_001910620.1 CDS rimM NC_010698.2 1164489 1165043 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1164489..1165043) Helicobacter pylori Shi470 6297175 YP_001910621.1 CDS HPSH_05935 NC_010698.2 1165044 1165391 R COG1837 Predicted RNA-binding protein (contains KH domain); hypothetical protein complement(1165044..1165391) Helicobacter pylori Shi470 6297145 YP_001910622.1 CDS rpsP NC_010698.2 1165408 1165638 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1165408..1165638) Helicobacter pylori Shi470 6297144 YP_001910623.1 CDS HPSH_05945 NC_010698.2 1165712 1167058 R COG0541 Signal recognition particle GTPase; signal recognition particle protein complement(1165712..1167058) Helicobacter pylori Shi470 6297143 YP_001910624.1 CDS valS NC_010698.2 1167073 1169691 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1167073..1169691) Helicobacter pylori Shi470 6297142 YP_001910625.1 CDS HPSH_05955 NC_010698.2 1169829 1170236 D binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1169829..1170236 Helicobacter pylori Shi470 6297141 YP_001910626.1 CDS murG NC_010698.2 1170248 1171309 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1170248..1171309 Helicobacter pylori Shi470 6297138 YP_001910627.1 CDS HPSH_05965 NC_010698.2 1171417 1173507 D outer membrane protein HopI 1171417..1173507 Helicobacter pylori Shi470 6297136 YP_001910628.1 CDS HPSH_05970 NC_010698.2 1173530 1177219 D outer membrane protein HopL 1173530..1177219 Helicobacter pylori Shi470 6297134 YP_001910629.1 CDS HPSH_05975 NC_010698.2 1177233 1177988 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1177233..1177988 Helicobacter pylori Shi470 6297133 YP_001910630.1 CDS HPSH_05980 NC_010698.2 1178032 1178565 D COG2184 Protein involved in cell division; cell filamentation protein 1178032..1178565 Helicobacter pylori Shi470 6297132 YP_001910631.1 CDS HPSH_05985 NC_010698.2 1178623 1179045 R COG0319 Predicted metal-dependent hydrolase; putative metalloprotease complement(1178623..1179045) Helicobacter pylori Shi470 6297131 YP_001910632.1 CDS HPSH_05990 NC_010698.2 1179098 1179592 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(1179098..1179592) Helicobacter pylori Shi470 6297130 YP_001910633.1 CDS HPSH_05995 NC_010698.2 1179681 1180262 R COG0586 Uncharacterized membrane-associated protein; hypothetical protein complement(1179681..1180262) Helicobacter pylori Shi470 6297129 YP_001910634.1 CDS HPSH_06000 NC_010698.2 1180384 1180575 D COG3197 Uncharacterized protein, possibly involved in nitrogen fixation; cation transport subunit for cbb3-type oxidase 1180384..1180575 Helicobacter pylori Shi470 6297128 YP_001910635.1 CDS HPSH_06005 NC_010698.2 1180601 1181572 D COG0492 Thioredoxin reductase; thioredoxin reductase 1180601..1181572 Helicobacter pylori Shi470 6297127 YP_001910636.1 CDS pgi NC_010698.2 1182809 1184446 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1182809..1184446 Helicobacter pylori Shi470 6297126 YP_001910637.1 CDS HPSH_06025 NC_010698.2 1184434 1184520 R hypothetical protein complement(1184434..1184520) Helicobacter pylori Shi470 6297125 YP_001910638.1 CDS HPSH_06030 NC_010698.2 1184755 1186170 D outer membrane protein HofH 1184755..1186170 Helicobacter pylori Shi470 6297120 YP_001910639.1 CDS HPSH_06035 NC_010698.2 1186222 1186341 R hypothetical protein complement(1186222..1186341) Helicobacter pylori Shi470 6296996 YP_001910640.1 CDS HPSH_06040 NC_010698.2 1186421 1188496 R COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein complement(1186421..1188496) Helicobacter pylori Shi470 6297244 YP_001910641.1 CDS HPSH_06045 NC_010698.2 1188707 1189360 D COG0765 ABC-type amino acid transport system, permease component; glutamine ABC transporter permease 1188707..1189360 Helicobacter pylori Shi470 6296547 YP_001910642.1 CDS HPSH_06050 NC_010698.2 1189363 1190034 D COG0765 ABC-type amino acid transport system, permease component; glutamine ABC transporter permease GlnP 1189363..1190034 Helicobacter pylori Shi470 6297115 YP_001910643.1 CDS HPSH_06055 NC_010698.2 1190036 1190782 D COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein GlnQ 1190036..1190782 Helicobacter pylori Shi470 6297114 YP_001910644.1 CDS HPSH_06060 NC_010698.2 1190831 1191664 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamine ABC transporter periplasmic glutamine-binding protein 1190831..1191664 Helicobacter pylori Shi470 6297113 YP_001910645.1 CDS HPSH_06065 NC_010698.2 1191657 1191725 D hypothetical protein 1191657..1191725 Helicobacter pylori Shi470 6297110 YP_001910646.1 CDS HPSH_06070 NC_010698.2 1191785 1192336 D hypothetical protein 1191785..1192336 Helicobacter pylori Shi470 6297109 YP_001910647.1 CDS HPSH_06075 NC_010698.2 1192552 1193775 R COG0738 Fucose permease; glucose/galactose transporter complement(1192552..1193775) Helicobacter pylori Shi470 6297107 YP_001910648.1 CDS HPSH_06080 NC_010698.2 1193905 1195212 R COG2252 Permeases; hypothetical protein complement(1193905..1195212) Helicobacter pylori Shi470 6297106 YP_001910649.1 CDS HPSH_06085 NC_010698.2 1195325 1195408 R hypothetical protein complement(1195325..1195408) Helicobacter pylori Shi470 6297105 YP_001910650.1 CDS HPSH_06090 NC_010698.2 1195547 1195684 D hypothetical protein 1195547..1195684 Helicobacter pylori Shi470 6297104 YP_001910651.1 CDS HPSH_06095 NC_010698.2 1195662 1197587 R outer membrane protein complement(1195662..1197587) Helicobacter pylori Shi470 6297102 YP_001910652.1 CDS HPSH_06100 NC_010698.2 1197737 1197847 D hypothetical protein 1197737..1197847 Helicobacter pylori Shi470 6297101 YP_001910653.1 CDS HPSH_06105 NC_010698.2 1197859 1198563 R COG0813 Purine-nucleoside phosphorylase; purine-nucleoside phosphorylase complement(1197859..1198563) Helicobacter pylori Shi470 6297099 YP_001910654.1 CDS HPSH_06110 NC_010698.2 1198560 1199801 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1198560..1199801) Helicobacter pylori Shi470 6297097 YP_001910655.1 CDS HPSH_06115 NC_010698.2 1199813 1201069 R COG1972 Nucleoside permease; pyrimidine nucleoside transport protein NupC complement(1199813..1201069) Helicobacter pylori Shi470 6297096 YP_001910656.1 CDS HPSH_06120 NC_010698.2 1201396 1202727 D COG0477 Permeases of the major facilitator superfamily; multidrug-efflux transporter 1201396..1202727 Helicobacter pylori Shi470 6297093 YP_001910657.1 CDS HPSH_06125 NC_010698.2 1202745 1203506 D COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; hypothetical protein 1202745..1203506 Helicobacter pylori Shi470 6297092 YP_001910658.1 CDS HPSH_06130 NC_010698.2 1203515 1204666 R COG0475 Kef-type K+ transport systems, membrane components; NA+/H+ antiporter NapA complement(1203515..1204666) Helicobacter pylori Shi470 6297091 YP_001910659.1 CDS HPSH_06135 NC_010698.2 1204692 1206071 R COG0534 Na+-driven multidrug efflux pump; hypothetical protein complement(1204692..1206071) Helicobacter pylori Shi470 6297084 YP_001910660.1 CDS HPSH_06140 NC_010698.2 1206231 1207403 R COG2814 Arabinose efflux permease; sugar efflux transporter complement(1206231..1207403) Helicobacter pylori Shi470 6297080 YP_001910661.1 CDS HPSH_06145 NC_010698.2 1207682 1208425 D COG3338 Carbonic anhydrase; carbonic anhydrase 1207682..1208425 Helicobacter pylori Shi470 6297078 YP_001910662.1 CDS HPSH_06150 NC_010698.2 1208712 1210526 D hypothetical protein 1208712..1210526 Helicobacter pylori Shi470 6297076 YP_001910663.1 CDS HPSH_06155 NC_010698.2 1210706 1211746 R COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase complement(1210706..1211746) Helicobacter pylori Shi470 6297075 YP_001910664.1 CDS hisS NC_010698.2 1211733 1213061 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1211733..1213061) Helicobacter pylori Shi470 6297074 YP_001910665.1 CDS HPSH_06165 NC_010698.2 1213123 1214172 D COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose-lps heptosyltransferase II 1213123..1214172 Helicobacter pylori Shi470 6297073 YP_001910666.1 CDS HPSH_06170 NC_010698.2 1214365 1214691 R hypothetical protein complement(1214365..1214691) Helicobacter pylori Shi470 6297070 YP_001910667.1 CDS HPSH_06175 NC_010698.2 1214875 1214985 D hypothetical protein 1214875..1214985 Helicobacter pylori Shi470 6297069 YP_001910668.1 CDS HPSH_06180 NC_010698.2 1215233 1217311 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1215233..1217311) Helicobacter pylori Shi470 6297067 YP_001910669.1 CDS HPSH_06185 NC_010698.2 1217323 1217790 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1217323..1217790) Helicobacter pylori Shi470 6297066 YP_001910670.1 CDS rpsL NC_010698.2 1217806 1218213 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1217806..1218213) Helicobacter pylori Shi470 6297065 YP_001910671.1 CDS HPSH_06195 NC_010698.2 1218301 1226973 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' complement(1218301..1226973) Helicobacter pylori Shi470 6297064 YP_001910672.1 CDS HPSH_06200 NC_010698.2 1226967 1227158 D hypothetical protein 1226967..1227158 Helicobacter pylori Shi470 6296841 YP_001910673.1 CDS rplL NC_010698.2 1227197 1227574 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1227197..1227574) Helicobacter pylori Shi470 6297094 YP_001910674.1 CDS rplJ NC_010698.2 1227620 1228114 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1227620..1228114) Helicobacter pylori Shi470 6296232 YP_001910675.1 CDS rplA NC_010698.2 1228223 1228927 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1228223..1228927) Helicobacter pylori Shi470 6297061 YP_001910676.1 CDS rplK NC_010698.2 1228972 1229397 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1228972..1229397) Helicobacter pylori Shi470 6297060 YP_001910677.1 CDS nusG NC_010698.2 1229415 1229942 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1229415..1229942) Helicobacter pylori Shi470 6297059 YP_001910678.1 CDS secE NC_010698.2 1229972 1230151 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1229972..1230151) Helicobacter pylori Shi470 6297058 YP_001910679.1 CDS rpmG NC_010698.2 1230405 1230563 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1230405..1230563) Helicobacter pylori Shi470 6297055 YP_001910680.1 CDS HPSH_06240 NC_010698.2 1230597 1231796 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1230597..1231796) Helicobacter pylori Shi470 6297054 YP_001910681.1 CDS HPSH_06245 NC_010698.2 1232519 1234255 D COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter ATP-binding protein 1232519..1234255 Helicobacter pylori Shi470 6297046 YP_001910682.1 CDS HPSH_06250 NC_010698.2 1234264 1234932 R COG0546 Predicted phosphatases; hypothetical protein complement(1234264..1234932) Helicobacter pylori Shi470 6297043 YP_001910683.1 CDS HPSH_06255 NC_010698.2 1235036 1236025 R COG3392 Adenine-specific DNA methylase; ulcer associated adenine specific DNA methyltransferase complement(1235036..1236025) Helicobacter pylori Shi470 6297042 YP_001910684.1 CDS HPSH_06260 NC_010698.2 1236380 1236523 R hypothetical protein complement(1236380..1236523) Helicobacter pylori Shi470 6297040 YP_001910685.1 CDS HPSH_06265 NC_010698.2 1236745 1237260 R COG1045 Serine acetyltransferase; serine acetyltransferase complement(1236745..1237260) Helicobacter pylori Shi470 6297039 YP_001910686.1 CDS HPSH_06270 NC_010698.2 1237301 1237420 R hypothetical protein complement(1237301..1237420) Helicobacter pylori Shi470 6297035 YP_001910687.1 CDS HPSH_06275 NC_010698.2 1237914 1238231 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1237914..1238231) Helicobacter pylori Shi470 6297029 YP_001910688.1 CDS HPSH_06280 NC_010698.2 1238368 1240434 R COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase complement(1238368..1240434) Helicobacter pylori Shi470 6297026 YP_001910689.1 CDS HPSH_06285 NC_010698.2 1240437 1241141 R COG1926 Predicted phosphoribosyltransferases; hypothetical protein complement(1240437..1241141) Helicobacter pylori Shi470 6297025 YP_001910690.1 CDS HPSH_06290 NC_010698.2 1241156 1243417 R COG1452 Organic solvent tolerance protein OstA; organic solvent tolerance protein complement(1241156..1243417) Helicobacter pylori Shi470 6297022 YP_001910691.1 CDS HPSH_06295 NC_010698.2 1243420 1243899 R hypothetical protein complement(1243420..1243899) Helicobacter pylori Shi470 6297021 YP_001910692.1 CDS HPSH_06300 NC_010698.2 1243941 1245215 R COG0151 Phosphoribosylamine-glycine ligase; glycinamide ribonucleotide synthetase complement(1243941..1245215) Helicobacter pylori Shi470 6297020 YP_001910693.1 CDS HPSH_06305 NC_010698.2 1245335 1245526 D hypothetical protein 1245335..1245526 Helicobacter pylori Shi470 6297019 YP_001910694.1 CDS HPSH_06310 NC_010698.2 1245528 1246214 R COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein complement(1245528..1246214) Helicobacter pylori Shi470 6297018 YP_001910695.1 CDS HPSH_06315 NC_010698.2 1246208 1246912 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(1246208..1246912) Helicobacter pylori Shi470 6296943 YP_001910696.1 CDS HPSH_06320 NC_010698.2 1246952 1249792 R COG0277 FAD/FMN-containing dehydrogenases; D-lactate dehydrogenase complement(1246952..1249792) Helicobacter pylori Shi470 6297199 YP_001910697.1 CDS HPSH_06325 NC_010698.2 1249864 1250196 D COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 1249864..1250196 Helicobacter pylori Shi470 6296196 YP_001910698.1 CDS hemD NC_010698.2 1250199 1250879 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1250199..1250879 Helicobacter pylori Shi470 6297015 YP_001910699.1 CDS HPSH_06335 NC_010698.2 1250926 1251318 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1250926..1251318 Helicobacter pylori Shi470 6297014 YP_001910700.1 CDS HPSH_06340 NC_010698.2 1251364 1252401 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1251364..1252401) Helicobacter pylori Shi470 6297012 YP_001910701.1 CDS HPSH_06345 NC_010698.2 1252497 1252787 D COG2863 Cytochrome c553; hypothetical protein 1252497..1252787 Helicobacter pylori Shi470 6297011 YP_001910702.1 CDS HPSH_06350 NC_010698.2 1252946 1253419 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1252946..1253419 Helicobacter pylori Shi470 6297009 YP_001910703.1 CDS HPSH_06355 NC_010698.2 1253413 1254630 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1253413..1254630 Helicobacter pylori Shi470 6297008 YP_001910704.1 CDS HPSH_06360 NC_010698.2 1254627 1255169 D hypothetical protein 1254627..1255169 Helicobacter pylori Shi470 6297007 YP_001910705.1 CDS HPSH_06365 NC_010698.2 1255166 1255822 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1255166..1255822 Helicobacter pylori Shi470 6297006 YP_001910706.1 CDS HPSH_06370 NC_010698.2 1255819 1256961 D COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase FolP 1255819..1256961 Helicobacter pylori Shi470 6297004 YP_001910707.1 CDS HPSH_06375 NC_010698.2 1256986 1257447 R hypothetical protein complement(1256986..1257447) Helicobacter pylori Shi470 6297002 YP_001910708.1 CDS HPSH_06380 NC_010698.2 1257841 1258737 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 1257841..1258737 Helicobacter pylori Shi470 6297001 YP_001910709.1 CDS HPSH_06385 NC_010698.2 1258741 1259988 D hypothetical protein 1258741..1259988 Helicobacter pylori Shi470 6297000 YP_001910710.1 CDS HPSH_06390 NC_010698.2 1259985 1260068 R hypothetical protein complement(1259985..1260068) Helicobacter pylori Shi470 6296999 YP_001910711.1 CDS HPSH_06395 NC_010698.2 1260067 1260618 D COG2952 Uncharacterized protein conserved in bacteria; hypothetical protein 1260067..1260618 Helicobacter pylori Shi470 6296998 YP_001910712.1 CDS HPSH_06400 NC_010698.2 1260618 1261745 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1260618..1261745 Helicobacter pylori Shi470 6296997 YP_001910713.1 CDS amiF NC_010698.2 1261913 1262917 D formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 1261913..1262917 Helicobacter pylori Shi470 6297119 YP_001910714.1 CDS HPSH_06410 NC_010698.2 1263105 1263206 R hypothetical protein complement(1263105..1263206) Helicobacter pylori Shi470 6296993 YP_001910715.1 CDS HPSH_06415 NC_010698.2 1263325 1263897 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1263325..1263897) Helicobacter pylori Shi470 6296992 YP_001910716.1 CDS alaS NC_010698.2 1263899 1266442 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1263899..1266442) Helicobacter pylori Shi470 6296991 YP_001910717.1 CDS HPSH_06425 NC_010698.2 1266561 1266791 D COG2841 Uncharacterized protein conserved in bacteria; hypothetical protein 1266561..1266791 Helicobacter pylori Shi470 6296990 YP_001910718.1 CDS HPSH_06430 NC_010698.2 1267051 1267137 R hypothetical protein complement(1267051..1267137) Helicobacter pylori Shi470 6296988 YP_001910719.1 CDS HPSH_06435 NC_010698.2 1267137 1267310 R hypothetical protein complement(1267137..1267310) Helicobacter pylori Shi470 6296987 YP_001910720.1 CDS HPSH_06440 NC_010698.2 1267314 1269428 R outer membrane protein complement(1267314..1269428) Helicobacter pylori Shi470 6296986 YP_001910721.1 CDS rpsR NC_010698.2 1269923 1270180 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1269923..1270180) Helicobacter pylori Shi470 6296985 YP_001910722.1 CDS HPSH_06450 NC_010698.2 1270203 1270748 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1270203..1270748) Helicobacter pylori Shi470 6296982 YP_001910723.1 CDS rpsF NC_010698.2 1270758 1271186 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1270758..1271186) Helicobacter pylori Shi470 6296980 YP_001910724.1 CDS HPSH_06460 NC_010698.2 1271329 1272351 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(1271329..1272351) Helicobacter pylori Shi470 6296979 YP_001910725.1 CDS HPSH_06465 NC_010698.2 1272341 1274275 R COG0557 Exoribonuclease R; 3'-5' exoribonuclease R complement(1272341..1274275) Helicobacter pylori Shi470 6296978 YP_001910726.1 CDS aroE NC_010698.2 1274275 1275066 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1274275..1275066) Helicobacter pylori Shi470 6296977 YP_001910727.1 CDS HPSH_06475 NC_010698.2 1275074 1275652 R hypothetical protein complement(1275074..1275652) Helicobacter pylori Shi470 6296975 YP_001910728.1 CDS HPSH_06490 NC_010698.2 1276716 1278497 R COG4166 ABC-type oligopeptide transport system, periplasmic component; hypothetical protein complement(1276716..1278497) Helicobacter pylori Shi470 6296974 YP_001910729.1 CDS HPSH_06495 NC_010698.2 1278498 1279478 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1278498..1279478) Helicobacter pylori Shi470 6296973 YP_001910730.1 CDS HPSH_06500 NC_010698.2 1279550 1280272 R COG0500 SAM-dependent methyltransferases; biotin synthesis protein BioC complement(1279550..1280272) Helicobacter pylori Shi470 6296972 YP_001910731.1 CDS secG NC_010698.2 1280392 1280991 D COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 1280392..1280991 Helicobacter pylori Shi470 6296799 YP_001910732.1 CDS frr NC_010698.2 1280991 1281548 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1280991..1281548 Helicobacter pylori Shi470 6297044 YP_001910733.1 CDS pyrE NC_010698.2 1281552 1282157 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1281552..1282157 Helicobacter pylori Shi470 6296203 YP_001910734.1 CDS HPSH_06520 NC_010698.2 1282147 1282611 D COG1714 Predicted membrane protein/domain; hypothetical protein 1282147..1282611 Helicobacter pylori Shi470 6296968 YP_001910735.1 CDS HPSH_06525 NC_010698.2 1282608 1283297 D COG0846 NAD-dependent protein deacetylases, SIR2 family; hypothetical protein 1282608..1283297 Helicobacter pylori Shi470 6296967 YP_001910736.1 CDS HPSH_06530 NC_010698.2 1283399 1283800 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A 1283399..1283800 Helicobacter pylori Shi470 6296966 YP_001910737.1 CDS HPSH_06535 NC_010698.2 1283800 1284279 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1283800..1284279 Helicobacter pylori Shi470 6296965 YP_001910738.1 CDS HPSH_06540 NC_010698.2 1284279 1285076 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C 1284279..1285076 Helicobacter pylori Shi470 6296964 YP_001910739.1 CDS HPSH_06545 NC_010698.2 1285078 1286307 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1285078..1286307 Helicobacter pylori Shi470 6296963 YP_001910740.1 CDS HPSH_06550 NC_010698.2 1286304 1286534 D NADH-ubiquinone oxidoreductase subunit E 1286304..1286534 Helicobacter pylori Shi470 6296958 YP_001910741.1 CDS HPSH_06555 NC_010698.2 1286531 1287523 D NADH-ubiquinone oxidoreductase subunit F 1286531..1287523 Helicobacter pylori Shi470 6296957 YP_001910742.1 CDS HPSH_06560 NC_010698.2 1287520 1290054 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1287520..1290054 Helicobacter pylori Shi470 6296955 YP_001910743.1 CDS HPSH_06565 NC_010698.2 1290051 1291040 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1290051..1291040 Helicobacter pylori Shi470 6296954 YP_001910744.1 CDS HPSH_06570 NC_010698.2 1291051 1291713 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1291051..1291713 Helicobacter pylori Shi470 6296953 YP_001910745.1 CDS HPSH_06575 NC_010698.2 1291706 1292254 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1291706..1292254 Helicobacter pylori Shi470 6296951 YP_001910746.1 CDS HPSH_06580 NC_010698.2 1292251 1292553 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1292251..1292553 Helicobacter pylori Shi470 6296950 YP_001910747.1 CDS HPSH_06585 NC_010698.2 1292556 1294394 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1292556..1294394 Helicobacter pylori Shi470 6296949 YP_001910748.1 CDS HPSH_06590 NC_010698.2 1294398 1295936 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1294398..1295936 Helicobacter pylori Shi470 6296948 YP_001910749.1 CDS HPSH_06595 NC_010698.2 1295923 1297401 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1295923..1297401 Helicobacter pylori Shi470 6296947 YP_001910750.1 CDS HPSH_06600 NC_010698.2 1297391 1299802 D COG1729 Uncharacterized protein conserved in bacteria; paralysed flagella protein 1297391..1299802 Helicobacter pylori Shi470 6297016 YP_001910751.1 CDS HPSH_06605 NC_010698.2 1299804 1301180 D COG1109 Phosphomannomutase; phosphomannomutase 1299804..1301180 Helicobacter pylori Shi470 6296941 YP_001910752.1 CDS HPSH_06610 NC_010698.2 1301291 1301599 D hypothetical protein 1301291..1301599 Helicobacter pylori Shi470 6296940 YP_001910753.1 CDS trpA NC_010698.2 1301830 1302618 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1301830..1302618) Helicobacter pylori Shi470 6296939 YP_001910754.1 CDS HPSH_06620 NC_010698.2 1302615 1303796 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1302615..1303796) Helicobacter pylori Shi470 6296938 YP_001910755.1 CDS HPSH_06625 NC_010698.2 1303798 1305156 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1303798..1305156) Helicobacter pylori Shi470 6296937 YP_001910756.1 CDS trpD NC_010698.2 1305149 1306156 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1305149..1306156) Helicobacter pylori Shi470 6296934 YP_001910757.1 CDS HPSH_06635 NC_010698.2 1306153 1306737 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1306153..1306737) Helicobacter pylori Shi470 6296930 YP_001910758.1 CDS HPSH_06640 NC_010698.2 1306734 1308371 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1306734..1308371) Helicobacter pylori Shi470 6296929 YP_001910759.1 CDS HPSH_06645 NC_010698.2 1308325 1309383 R COG0859 ADP-heptose:LPS heptosyltransferase; hypothetical protein complement(1308325..1309383) Helicobacter pylori Shi470 6296928 YP_001910760.1 CDS HPSH_06650 NC_010698.2 1309451 1310143 R COG2503 Predicted secreted acid phosphatase; hypothetical protein complement(1309451..1310143) Helicobacter pylori Shi470 6296922 YP_001910761.1 CDS HPSH_06655 NC_010698.2 1310313 1310861 D COG2353 Uncharacterized conserved protein; hypothetical protein 1310313..1310861 Helicobacter pylori Shi470 6296921 YP_001910762.1 CDS HPSH_06660 NC_010698.2 1310836 1310973 R hypothetical protein complement(1310836..1310973) Helicobacter pylori Shi470 6296920 YP_001910763.1 CDS HPSH_06665 NC_010698.2 1311446 1312102 D COG0819 Putative transcription activator; putative transcriptional regulator 1311446..1312102 Helicobacter pylori Shi470 6296918 YP_001910764.1 CDS HPSH_06670 NC_010698.2 1312224 1312886 D COG3201 Nicotinamide mononucleotide transporter; nicotinamide mononucleotide transporter 1312224..1312886 Helicobacter pylori Shi470 6296916 YP_001910765.1 CDS HPSH_06675 NC_010698.2 1312874 1313488 D COG1564 Thiamine pyrophosphokinase; hypothetical protein 1312874..1313488 Helicobacter pylori Shi470 6296915 YP_001910766.1 CDS HPSH_06680 NC_010698.2 1313800 1313952 D hypothetical protein 1313800..1313952 Helicobacter pylori Shi470 6296914 YP_001910767.1 CDS rplQ NC_010698.2 1313996 1314346 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1313996..1314346) Helicobacter pylori Shi470 6296892 YP_001910768.1 CDS HPSH_06690 NC_010698.2 1314346 1315380 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1314346..1315380) Helicobacter pylori Shi470 6297146 YP_001910769.1 CDS rpsD NC_010698.2 1315392 1316018 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1315392..1316018) Helicobacter pylori Shi470 6297313 YP_001910770.1 CDS HPSH_06700 NC_010698.2 1316028 1316423 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1316028..1316423) Helicobacter pylori Shi470 6296912 YP_001910771.1 CDS rpsM NC_010698.2 1316446 1316808 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1316446..1316808) Helicobacter pylori Shi470 6296911 YP_001910772.1 CDS rpmJ NC_010698.2 1316812 1316925 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(1316812..1316925) Helicobacter pylori Shi470 6296910 YP_001910773.1 CDS infA NC_010698.2 1317004 1317222 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1317004..1317222) Helicobacter pylori Shi470 6296909 YP_001910774.1 CDS HPSH_06720 NC_010698.2 1317222 1317983 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(1317222..1317983) Helicobacter pylori Shi470 6296908 YP_001910775.1 CDS secY NC_010698.2 1317983 1319245 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1317983..1319245) Helicobacter pylori Shi470 6296907 YP_001910776.1 CDS rplO NC_010698.2 1319283 1319684 R late assembly protein; 50S ribosomal protein L15 complement(1319283..1319684) Helicobacter pylori Shi470 6296906 YP_001910777.1 CDS rpsE NC_010698.2 1319702 1320163 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1319702..1320163) Helicobacter pylori Shi470 6296905 YP_001910778.1 CDS rplR NC_010698.2 1320160 1320516 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1320160..1320516) Helicobacter pylori Shi470 6296904 YP_001910779.1 CDS rplF NC_010698.2 1320530 1321066 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1320530..1321066) Helicobacter pylori Shi470 6296901 YP_001910780.1 CDS rpsH NC_010698.2 1321077 1321472 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1321077..1321472) Helicobacter pylori Shi470 6296900 YP_001910781.1 CDS rpsN NC_010698.2 1321482 1321667 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 complement(1321482..1321667) Helicobacter pylori Shi470 6296899 YP_001910782.1 CDS rplE NC_010698.2 1321677 1322222 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1321677..1322222) Helicobacter pylori Shi470 6296897 YP_001910783.1 CDS rplX NC_010698.2 1322235 1322456 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1322235..1322456) Helicobacter pylori Shi470 6296896 YP_001910784.1 CDS rplN NC_010698.2 1322456 1322824 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1322456..1322824) Helicobacter pylori Shi470 6296894 YP_001910785.1 CDS rpsQ NC_010698.2 1322827 1323087 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1322827..1323087) Helicobacter pylori Shi470 6296893 YP_001910786.1 CDS HPSH_06780 NC_010698.2 1323101 1323301 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1323101..1323301) Helicobacter pylori Shi470 6296913 YP_001910787.1 CDS rplP NC_010698.2 1323288 1323713 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1323288..1323713) Helicobacter pylori Shi470 6296888 YP_001910788.1 CDS rpsC NC_010698.2 1323716 1324420 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1323716..1324420) Helicobacter pylori Shi470 6296887 YP_001910789.1 CDS rplV NC_010698.2 1324424 1324792 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1324424..1324792) Helicobacter pylori Shi470 6296886 YP_001910790.1 CDS rpsS NC_010698.2 1324802 1325083 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1324802..1325083) Helicobacter pylori Shi470 6296885 YP_001910791.1 CDS rplB NC_010698.2 1325087 1325923 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1325087..1325923) Helicobacter pylori Shi470 6296884 YP_001910792.1 CDS rplW NC_010698.2 1325939 1326220 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1325939..1326220) Helicobacter pylori Shi470 6296883 YP_001910793.1 CDS rplD NC_010698.2 1326224 1326871 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1326224..1326871) Helicobacter pylori Shi470 6296882 YP_001910794.1 CDS rplC NC_010698.2 1326906 1327481 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1326906..1327481) Helicobacter pylori Shi470 6296881 YP_001910795.1 CDS rpsJ NC_010698.2 1327518 1327832 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1327518..1327832) Helicobacter pylori Shi470 6296880 YP_001910796.1 CDS HPSH_06830 NC_010698.2 1327987 1329120 D COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; ATP-binding protein 1327987..1329120 Helicobacter pylori Shi470 6296879 YP_001910797.1 CDS HPSH_06835 NC_010698.2 1329340 1329921 D hypothetical protein 1329340..1329921 Helicobacter pylori Shi470 6296878 YP_001910798.1 CDS rnhB NC_010698.2 1329895 1330509 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1329895..1330509) Helicobacter pylori Shi470 6296877 YP_001910799.1 CDS HPSH_06845 NC_010698.2 1330540 1330770 R hypothetical protein complement(1330540..1330770) Helicobacter pylori Shi470 6296875 YP_001910800.1 CDS fumC NC_010698.2 1330793 1332184 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1330793..1332184) Helicobacter pylori Shi470 6296873 YP_001910801.1 CDS HPSH_06855 NC_010698.2 1332359 1332736 D hypothetical protein 1332359..1332736 Helicobacter pylori Shi470 6296872 YP_001910802.1 CDS HPSH_06860 NC_010698.2 1332792 1333979 D hypothetical protein 1332792..1333979 Helicobacter pylori Shi470 6296871 YP_001910803.1 CDS HPSH_06865 NC_010698.2 1333976 1334983 D COG0845 Membrane-fusion protein; cation efflux system protein CzcA 1333976..1334983 Helicobacter pylori Shi470 6296870 YP_001910804.1 CDS HPSH_06870 NC_010698.2 1334984 1338097 D COG3696 Putative silver efflux pump; cation efflux system protein CzcA 1334984..1338097 Helicobacter pylori Shi470 6296759 YP_001910805.1 CDS HPSH_06875 NC_010698.2 1338094 1338441 R COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance); hypothetical protein complement(1338094..1338441) Helicobacter pylori Shi470 6296994 YP_001910806.1 CDS HPSH_06880 NC_010698.2 1338435 1339121 R COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); branched-chain amino acid transport protein complement(1338435..1339121) Helicobacter pylori Shi470 6296104 YP_001910807.1 CDS HPSH_06885 NC_010698.2 1339132 1340241 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(1339132..1340241) Helicobacter pylori Shi470 6296867 YP_001910808.1 CDS HPSH_06890 NC_010698.2 1340420 1341496 D hypothetical protein 1340420..1341496 Helicobacter pylori Shi470 6296864 YP_001910809.1 CDS HPSH_06895 NC_010698.2 1341698 1341811 D hypothetical protein 1341698..1341811 Helicobacter pylori Shi470 6296861 YP_001910810.1 CDS HPSH_06900 NC_010698.2 1342021 1342386 D COG1432 Uncharacterized conserved protein; hypothetical protein 1342021..1342386 Helicobacter pylori Shi470 6296860 YP_001910811.1 CDS mnmA NC_010698.2 1342447 1343475 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1342447..1343475) Helicobacter pylori Shi470 6296858 YP_001910812.1 CDS HPSH_06910 NC_010698.2 1343616 1344377 D COG2214 DnaJ-class molecular chaperone; hypothetical protein 1343616..1344377 Helicobacter pylori Shi470 6296857 YP_001910813.1 CDS HPSH_06915 NC_010698.2 1344374 1344889 R COG1057 Nicotinic acid mononucleotide adenylyltransferase; hypothetical protein complement(1344374..1344889) Helicobacter pylori Shi470 6296854 YP_001910814.1 CDS HPSH_06920 NC_010698.2 1344882 1345328 R Inhibits transcription at high concentrations of nickel; nickel responsive regulator complement(1344882..1345328) Helicobacter pylori Shi470 6296853 YP_001910815.1 CDS HPSH_06925 NC_010698.2 1345665 1346102 D COG0811 Biopolymer transport proteins; biopolymer transport protein ExbB 1345665..1346102 Helicobacter pylori Shi470 6296852 YP_001910816.1 CDS HPSH_06930 NC_010698.2 1346099 1346488 D COG0848 Biopolymer transport protein; biopolymer transport protein 1346099..1346488 Helicobacter pylori Shi470 6296851 YP_001910817.1 CDS HPSH_06935 NC_010698.2 1346454 1347308 D COG0810 Periplasmic protein TonB, links inner and outer membranes; siderophore-mediated iron transport protein TonB 1346454..1347308 Helicobacter pylori Shi470 6296850 YP_001910818.1 CDS HPSH_06950 NC_010698.2 1347973 1348701 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein complement(1347973..1348701) Helicobacter pylori Shi470 6296849 YP_001910819.1 CDS HPSH_06955 NC_010698.2 1348708 1349664 R COG0598 Mg2+ and Co2+ transporters; magnesium and cobalt transport protein complement(1348708..1349664) Helicobacter pylori Shi470 6296848 YP_001910820.1 CDS pgk NC_010698.2 1349680 1350888 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1349680..1350888) Helicobacter pylori Shi470 6296847 YP_001910821.1 CDS HPSH_06965 NC_010698.2 1350904 1351896 R COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase complement(1350904..1351896) Helicobacter pylori Shi470 6296844 YP_001910822.1 CDS HPSH_06970 NC_010698.2 1351985 1352686 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1351985..1352686) Helicobacter pylori Shi470 6297062 YP_001910823.1 CDS HPSH_06975 NC_010698.2 1352683 1353405 R COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-glycerol-3-phosphate acyltransferase complement(1352683..1353405) Helicobacter pylori Shi470 6296838 YP_001910824.1 CDS HPSH_06980 NC_010698.2 1353392 1354555 R hypothetical protein complement(1353392..1354555) Helicobacter pylori Shi470 6296837 YP_001910825.1 CDS HPSH_06985 NC_010698.2 1354562 1355926 R COG0793 Periplasmic protease; protease complement(1354562..1355926) Helicobacter pylori Shi470 6296836 YP_001910826.1 CDS HPSH_06990 NC_010698.2 1356037 1356270 R adenine specific DNA methyltransferase complement(1356037..1356270) Helicobacter pylori Shi470 6296835 YP_001910827.1 CDS HPSH_06995 NC_010698.2 1356335 1357228 R hypothetical protein complement(1356335..1357228) Helicobacter pylori Shi470 6296834 YP_001910828.1 CDS HPSH_07000 NC_010698.2 1357228 1358307 R COG0863 DNA modification methylase; adenine specific DNA methyltransferase complement(1357228..1358307) Helicobacter pylori Shi470 6296833 YP_001910829.1 CDS HPSH_07005 NC_010698.2 1358427 1358654 R adenine specific DNA methyltransferase complement(1358427..1358654) Helicobacter pylori Shi470 6296832 YP_001910830.1 CDS HPSH_07010 NC_010698.2 1358699 1361935 R COG4889 Predicted helicase; hypothetical protein complement(1358699..1361935) Helicobacter pylori Shi470 6296831 YP_001910831.1 CDS HPSH_07015 NC_010698.2 1361959 1362780 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(1361959..1362780) Helicobacter pylori Shi470 6296830 YP_001910832.1 CDS HPSH_07020 NC_010698.2 1362780 1363790 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(1362780..1363790) Helicobacter pylori Shi470 6296829 YP_001910833.1 CDS HPSH_07025 NC_010698.2 1363780 1364583 R catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase complement(1363780..1364583) Helicobacter pylori Shi470 6296828 YP_001910834.1 CDS HPSH_07030 NC_010698.2 1364580 1365083 R hypothetical protein complement(1364580..1365083) Helicobacter pylori Shi470 6296827 YP_001910835.1 CDS HPSH_07035 NC_010698.2 1365096 1365590 R hypothetical protein complement(1365096..1365590) Helicobacter pylori Shi470 6296826 YP_001910836.1 CDS ubiA NC_010698.2 1365583 1366467 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase complement(1365583..1366467) Helicobacter pylori Shi470 6296825 YP_001910837.1 CDS HPSH_07045 NC_010698.2 1366496 1367809 R COG0658 Predicted membrane metal-binding protein; competence locus E complement(1366496..1367809) Helicobacter pylori Shi470 6296824 YP_001910838.1 CDS HPSH_07050 NC_010698.2 1367806 1369272 R unwinds double stranded DNA; replicative DNA helicase complement(1367806..1369272) Helicobacter pylori Shi470 6296823 YP_001910839.1 CDS HPSH_07055 NC_010698.2 1369283 1370677 R COG0062 Uncharacterized conserved protein; hypothetical protein complement(1369283..1370677) Helicobacter pylori Shi470 6296635 YP_001910840.1 CDS HPSH_07060 NC_010698.2 1370680 1371813 R COG0642 Signal transduction histidine kinase; signal-transducing protein, histidine kinase complement(1370680..1371813) Helicobacter pylori Shi470 6296839 YP_001910841.1 CDS HPSH_07065 NC_010698.2 1371848 1372489 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative transcriptional regulator complement(1371848..1372489) Helicobacter pylori Shi470 6296164 YP_001910842.1 CDS HPSH_07070 NC_010698.2 1372577 1373635 R type IIS restriction enzyme R protein complement(1372577..1373635) Helicobacter pylori Shi470 6296821 YP_001910843.1 CDS HPSH_07075 NC_010698.2 1373810 1374652 D type II restriction endonuclease 1373810..1374652 Helicobacter pylori Shi470 6296819 YP_001910844.1 CDS HPSH_07080 NC_010698.2 1374652 1375545 D COG0338 Site-specific DNA methylase; adenine-specific DNA metylase 1374652..1375545 Helicobacter pylori Shi470 6296817 YP_001910845.1 CDS HPSH_07085 NC_010698.2 1375517 1376959 D COG2189 Adenine specific DNA methylase Mod; adenine-specific DNA methylase 1375517..1376959 Helicobacter pylori Shi470 6296816 YP_001910846.1 CDS HPSH_07090 NC_010698.2 1376917 1377993 D COG2189 Adenine specific DNA methylase Mod; adenine-specific DNA methylase 1376917..1377993 Helicobacter pylori Shi470 6296815 YP_001910847.1 CDS HPSH_07095 NC_010698.2 1378003 1380915 D COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type III restriction enzyme R protein 1378003..1380915 Helicobacter pylori Shi470 6296814 YP_001910848.1 CDS HPSH_07100 NC_010698.2 1380965 1381711 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(1380965..1381711) Helicobacter pylori Shi470 6296813 YP_001910849.1 CDS HPSH_07105 NC_010698.2 1381715 1382758 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(1381715..1382758) Helicobacter pylori Shi470 6296812 YP_001910850.1 CDS clpX NC_010698.2 1382801 1384147 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1382801..1384147) Helicobacter pylori Shi470 6296810 YP_001910851.1 CDS HPSH_07115 NC_010698.2 1384149 1384961 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1384149..1384961) Helicobacter pylori Shi470 6296809 YP_001910852.1 CDS fabZ NC_010698.2 1384964 1385443 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1384964..1385443) Helicobacter pylori Shi470 6296808 YP_001910853.1 CDS HPSH_07125 NC_010698.2 1385626 1386015 R binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW complement(1385626..1386015) Helicobacter pylori Shi470 6296806 YP_001910854.1 CDS HPSH_07130 NC_010698.2 1386232 1386378 D hypothetical protein 1386232..1386378 Helicobacter pylori Shi470 6296805 YP_001910855.1 CDS HPSH_07135 NC_010698.2 1386421 1387083 D COG4105 DNA uptake lipoprotein; competence lipoprotein 1386421..1387083 Helicobacter pylori Shi470 6296804 YP_001910856.1 CDS HPSH_07140 NC_010698.2 1387124 1389592 D COG0466 ATP-dependent Lon protease, bacterial type; ATP-dependent protease 1387124..1389592 Helicobacter pylori Shi470 6296803 YP_001910857.1 CDS HPSH_07145 NC_010698.2 1389601 1390428 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1389601..1390428 Helicobacter pylori Shi470 6296802 YP_001910858.1 CDS HPSH_07150 NC_010698.2 1390714 1391562 R COG1864 DNA/RNA endonuclease G, NUC1; putative endonuclease complement(1390714..1391562) Helicobacter pylori Shi470 6296801 YP_001910859.1 CDS HPSH_07155 NC_010698.2 1391687 1393405 R COG2189 Adenine specific DNA methylase Mod; putative type III restriction enzyme M protein complement(1391687..1393405) Helicobacter pylori Shi470 6296970 YP_001910860.1 CDS HPSH_07170 NC_010698.2 1396155 1397003 D catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1396155..1397003 Helicobacter pylori Shi470 6296797 YP_001910861.1 CDS HPSH_07175 NC_010698.2 1397003 1397881 D COG1295 Predicted membrane protein; putative ribonuclease N 1397003..1397881 Helicobacter pylori Shi470 6296796 YP_001910862.1 CDS HPSH_07180 NC_010698.2 1402463 1402729 R hypothetical protein complement(1402463..1402729) Helicobacter pylori Shi470 6296793 YP_001910863.1 CDS HPSH_07185 NC_010698.2 1403060 1404400 R hypothetical protein complement(1403060..1404400) Helicobacter pylori Shi470 6296792 YP_001910864.1 CDS HPSH_07190 NC_010698.2 1404416 1404778 R hypothetical protein complement(1404416..1404778) Helicobacter pylori Shi470 6296791 YP_001910865.1 CDS HPSH_07195 NC_010698.2 1404799 1405491 R hypothetical protein complement(1404799..1405491) Helicobacter pylori Shi470 6296790 YP_001910866.1 CDS HPSH_07200 NC_010698.2 1405754 1406194 R NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(1405754..1406194) Helicobacter pylori Shi470 6296789 YP_001910867.1 CDS HPSH_07205 NC_010698.2 1406253 1406594 D COG0799 Uncharacterized homolog of plant Iojap protein; hypothetical protein 1406253..1406594 Helicobacter pylori Shi470 6296788 YP_001910868.1 CDS miaA NC_010698.2 1406665 1407495 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1406665..1407495 Helicobacter pylori Shi470 6296787 YP_001910869.1 CDS HPSH_07215 NC_010698.2 1407500 1408603 D COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glucosyltransferase 1407500..1408603 Helicobacter pylori Shi470 6296786 YP_001910870.1 CDS murB NC_010698.2 1410160 1410939 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1410160..1410939) Helicobacter pylori Shi470 6296785 YP_001910871.1 CDS fliQ NC_010698.2 1410943 1411194 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(1410943..1411194) Helicobacter pylori Shi470 6296784 YP_001910872.1 CDS fliI NC_010698.2 1411220 1412524 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(1411220..1412524) Helicobacter pylori Shi470 6296714 YP_001910873.1 CDS HPSH_07250 NC_010698.2 1412525 1413439 R COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; type IV secretion system ATPase complement(1412525..1413439) Helicobacter pylori Shi470 6296942 YP_001910874.1 CDS ileS NC_010698.2 1413456 1416218 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1413456..1416218) Helicobacter pylori Shi470 6296355 YP_001910875.1 CDS HPSH_07260 NC_010698.2 1416253 1416510 R COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); hypothetical protein complement(1416253..1416510) Helicobacter pylori Shi470 6296782 YP_001910876.1 CDS HPSH_07265 NC_010698.2 1416612 1417232 D hypothetical protein 1416612..1417232 Helicobacter pylori Shi470 6296781 YP_001910877.1 CDS HPSH_07270 NC_010698.2 1417498 1417752 R hypothetical protein complement(1417498..1417752) Helicobacter pylori Shi470 6296780 YP_001910878.1 CDS HPSH_07275 NC_010698.2 1417939 1419012 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(1417939..1419012) Helicobacter pylori Shi470 6296779 YP_001910879.1 CDS HPSH_07280 NC_010698.2 1419009 1419998 R COG0794 Predicted sugar phosphate isomerase involved in capsule formation; polysialic acid capsule expression protein KpsF complement(1419009..1419998) Helicobacter pylori Shi470 6296778 YP_001910880.1 CDS HPSH_07285 NC_010698.2 1419982 1422075 R COG1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain; ATP-binding protein complement(1419982..1422075) Helicobacter pylori Shi470 6296777 YP_001910881.1 CDS ksgA NC_010698.2 1422109 1422924 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1422109..1422924) Helicobacter pylori Shi470 6296776 YP_001910882.1 CDS HPSH_07295 NC_010698.2 1423717 1423809 D hypothetical protein 1423717..1423809 Helicobacter pylori Shi470 6296775 YP_001910883.1 CDS HPSH_07300 NC_010698.2 1423889 1424998 R COG0732 Restriction endonuclease S subunits; type I R-M system specificity subunit complement(1423889..1424998) Helicobacter pylori Shi470 6296774 YP_001910884.1 CDS HPSH_07305 NC_010698.2 1425011 1425892 R COG0788 Formyltetrahydrofolate hydrolase; formyltetrahydrofolate hydrolase PurU complement(1425011..1425892) Helicobacter pylori Shi470 6296773 YP_001910885.1 CDS HPSH_07310 NC_010698.2 1425895 1426773 R COG0616 Periplasmic serine proteases (ClpP class); protease IV PspA complement(1425895..1426773) Helicobacter pylori Shi470 6296772 YP_001910886.1 CDS HPSH_07315 NC_010698.2 1426844 1427116 D hypothetical protein 1426844..1427116 Helicobacter pylori Shi470 6296768 YP_001910887.1 CDS HPSH_07320 NC_010698.2 1427160 1427324 R hypothetical protein complement(1427160..1427324) Helicobacter pylori Shi470 6296767 YP_001910888.1 CDS HPSH_07325 NC_010698.2 1427349 1428023 D COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein 1427349..1428023 Helicobacter pylori Shi470 6296764 YP_001910889.1 CDS HPSH_07330 NC_010698.2 1428032 1428319 D hypothetical protein 1428032..1428319 Helicobacter pylori Shi470 6296763 YP_001910890.1 CDS HPSH_07335 NC_010698.2 1428309 1428470 D hypothetical protein 1428309..1428470 Helicobacter pylori Shi470 6296762 YP_001910891.1 CDS HPSH_07340 NC_010698.2 1428489 1428962 R hypothetical protein complement(1428489..1428962) Helicobacter pylori Shi470 6296869 YP_001910892.1 CDS HPSH_07345 NC_010698.2 1428967 1429149 D hypothetical protein 1428967..1429149 Helicobacter pylori Shi470 6296757 YP_001910893.1 CDS HPSH_07350 NC_010698.2 1429495 1429797 D COG3676 Transposase and inactivated derivatives; hypothetical protein 1429495..1429797 Helicobacter pylori Shi470 6296756 YP_001910894.1 CDS HPSH_07355 NC_010698.2 1429816 1430352 D hypothetical protein 1429816..1430352 Helicobacter pylori Shi470 6296755 YP_001910895.1 CDS HPSH_07360 NC_010698.2 1430336 1430443 D hypothetical protein 1430336..1430443 Helicobacter pylori Shi470 6296754 YP_001910896.1 CDS HPSH_07365 NC_010698.2 1430830 1430925 R hypothetical protein complement(1430830..1430925) Helicobacter pylori Shi470 6296753 YP_001910897.1 CDS HPSH_07370 NC_010698.2 1432988 1433767 R hypothetical protein complement(1432988..1433767) Helicobacter pylori Shi470 6296750 YP_001910898.1 CDS HPSH_07375 NC_010698.2 1433891 1434379 D COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase B 1433891..1434379 Helicobacter pylori Shi470 6296749 YP_001910899.1 CDS HPSH_07380 NC_010698.2 1434397 1434627 D affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator 1434397..1434627 Helicobacter pylori Shi470 6296747 YP_001910900.1 CDS HPSH_07385 NC_010698.2 1434627 1435430 D catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1434627..1435430 Helicobacter pylori Shi470 6296746 YP_001910901.1 CDS smpB NC_010698.2 1435427 1435885 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1435427..1435885 Helicobacter pylori Shi470 6296745 YP_001910902.1 CDS HPSH_07395 NC_010698.2 1435888 1436340 D COG0811 Biopolymer transport proteins; biopolymer transport protein 1435888..1436340 Helicobacter pylori Shi470 6296744 YP_001910903.1 CDS HPSH_07400 NC_010698.2 1436351 1436752 D COG0848 Biopolymer transport protein; biopolymer transport protein 1436351..1436752 Helicobacter pylori Shi470 6296743 YP_001910904.1 CDS rpmH NC_010698.2 1436826 1436960 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1436826..1436960 Helicobacter pylori Shi470 6296741 YP_001910905.1 CDS HPSH_07410 NC_010698.2 1436920 1437405 D COG0594 RNase P protein component; ribonuclease P, protein component RnpA 1436920..1437405 Helicobacter pylori Shi470 6296739 YP_001910906.1 CDS HPSH_07415 NC_010698.2 1437392 1437748 D COG0759 Uncharacterized conserved protein; hypothetical protein 1437392..1437748 Helicobacter pylori Shi470 6296590 YP_001910907.1 CDS HPSH_07420 NC_010698.2 1437754 1439394 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 1437754..1439394 Helicobacter pylori Shi470 6296798 YP_001910908.1 CDS HPSH_07425 NC_010698.2 1439394 1440191 D COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain; hypothetical protein 1439394..1440191 Helicobacter pylori Shi470 6297405 YP_001910909.1 CDS trmE NC_010698.2 1440184 1441536 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1440184..1441536 Helicobacter pylori Shi470 6296737 YP_001910910.1 CDS HPSH_07435 NC_010698.2 1441740 1443962 D putative Outer membrane protein 1441740..1443962 Helicobacter pylori Shi470 6296736 YP_001910911.1 CDS HPSH_07440 NC_010698.2 1443959 1444102 R hypothetical protein complement(1443959..1444102) Helicobacter pylori Shi470 6296735 YP_001910912.1 CDS HPSH_07445 NC_010698.2 1444482 1445393 R hypothetical protein complement(1444482..1445393) Helicobacter pylori Shi470 6296734 YP_001910913.1 CDS HPSH_07450 NC_010698.2 1445403 1445744 R COG0481 Membrane GTPase LepA; hypothetical protein complement(1445403..1445744) Helicobacter pylori Shi470 6296731 YP_001910914.1 CDS HPSH_07455 NC_010698.2 1445752 1446279 R membrane-associated lipoprotein complement(1445752..1446279) Helicobacter pylori Shi470 6296730 YP_001910915.1 CDS HPSH_07460 NC_010698.2 1446303 1446935 R hypothetical protein complement(1446303..1446935) Helicobacter pylori Shi470 6296729 YP_001910916.1 CDS HPSH_07465 NC_010698.2 1447292 1447606 R COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin complement(1447292..1447606) Helicobacter pylori Shi470 6296727 YP_001910917.1 CDS HPSH_07470 NC_010698.2 1447661 1448434 R COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; hypothetical protein complement(1447661..1448434) Helicobacter pylori Shi470 6296725 YP_001910918.1 CDS dnaE NC_010698.2 1448431 1452066 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(1448431..1452066) Helicobacter pylori Shi470 6296724 YP_001910919.1 CDS HPSH_07480 NC_010698.2 1452214 1453266 D COG1858 Cytochrome c peroxidase; cytochrome c551 peroxidase 1452214..1453266 Helicobacter pylori Shi470 6296723 YP_001910920.1 CDS HPSH_07485 NC_010698.2 1453269 1453358 R hypothetical protein complement(1453269..1453358) Helicobacter pylori Shi470 6296721 YP_001910921.1 CDS HPSH_07490 NC_010698.2 1453443 1454030 R COG3187 Heat shock protein; putative secreted motility protein complement(1453443..1454030) Helicobacter pylori Shi470 6296720 YP_001910922.1 CDS HPSH_07495 NC_010698.2 1454049 1454726 R hypothetical protein complement(1454049..1454726) Helicobacter pylori Shi470 6296719 YP_001910923.1 CDS HPSH_07500 NC_010698.2 1454729 1455544 R COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; ABC transport system substrate binding protein complement(1454729..1455544) Helicobacter pylori Shi470 6296718 YP_001910924.1 CDS HPSH_07505 NC_010698.2 1455529 1456317 R COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; ABC transporter ATP-binding protein complement(1455529..1456317) Helicobacter pylori Shi470 6296717 YP_001910925.1 CDS HPSH_07510 NC_010698.2 1456314 1457447 R COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; hypothetical protein complement(1456314..1457447) Helicobacter pylori Shi470 6296716 YP_001910926.1 CDS HPSH_07515 NC_010698.2 1457581 1458276 D outer membrane protein 1457581..1458276 Helicobacter pylori Shi470 6296783 YP_001910927.1 CDS HPSH_07520 NC_010698.2 1458281 1459303 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1458281..1459303) Helicobacter pylori Shi470 6296712 YP_001910928.1 CDS HPSH_07525 NC_010698.2 1459354 1460100 R outer membrane protein complement(1459354..1460100) Helicobacter pylori Shi470 6296710 YP_001910929.1 CDS HPSH_07530 NC_010698.2 1460215 1462896 R COG0258 5'-3' exonuclease (including N-terminal domain of PolI); DNA polymerase I PolA complement(1460215..1462896) Helicobacter pylori Shi470 6296709 YP_002154434.1 CDS HPSH_07540 NC_010698.2 1463549 1466224 R type II restriction modification enzyme methyltransferase complement(1463549..1466224) Helicobacter pylori Shi470 6972671 YP_001910930.1 CDS HPSH_07545 NC_010698.2 1466257 1466832 R hypothetical protein complement(1466257..1466832) Helicobacter pylori Shi470 6296708 YP_001910931.1 CDS tmk NC_010698.2 1466820 1467395 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1466820..1467395) Helicobacter pylori Shi470 6296707 YP_001910932.1 CDS coaD NC_010698.2 1467397 1467870 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1467397..1467870) Helicobacter pylori Shi470 6296706 YP_001910933.1 CDS HPSH_07560 NC_010698.2 1467870 1468433 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1467870..1468433) Helicobacter pylori Shi470 6296705 YP_001910934.1 CDS HPSH_07565 NC_010698.2 1468414 1468518 D hypothetical protein 1468414..1468518 Helicobacter pylori Shi470 6296704 YP_001910935.1 CDS flgA NC_010698.2 1468443 1469099 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1468443..1469099) Helicobacter pylori Shi470 6296702 YP_001910936.1 CDS HPSH_07575 NC_010698.2 1469096 1471141 R COG0210 Superfamily I DNA and RNA helicases; DNA helicase II complement(1469096..1471141) Helicobacter pylori Shi470 6296701 YP_001910937.1 CDS HPSH_07580 NC_010698.2 1471141 1473675 R COG0457 FOG: TPR repeat; hypothetical protein complement(1471141..1473675) Helicobacter pylori Shi470 6296700 YP_001910938.1 CDS HPSH_07585 NC_010698.2 1473685 1474932 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(1473685..1474932) Helicobacter pylori Shi470 6296699 YP_001910939.1 CDS HPSH_07590 NC_010698.2 1474933 1475730 R COG0388 Predicted amidohydrolase; hypothetical protein complement(1474933..1475730) Helicobacter pylori Shi470 6296698 YP_001910940.1 CDS HPSH_07595 NC_010698.2 1475734 1475994 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1475734..1475994) Helicobacter pylori Shi470 6296697 YP_001910941.1 CDS ubiE NC_010698.2 1476004 1476744 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(1476004..1476744) Helicobacter pylori Shi470 6296696 YP_001910942.1 CDS HPSH_07605 NC_010698.2 1476754 1477200 R COG1981 Predicted membrane protein; hypothetical protein complement(1476754..1477200) Helicobacter pylori Shi470 6296675 YP_001910943.1 CDS HPSH_07610 NC_010698.2 1477211 1477783 R COG1739 Uncharacterized conserved protein; hypothetical protein complement(1477211..1477783) Helicobacter pylori Shi470 6296889 YP_001910944.1 CDS HPSH_07615 NC_010698.2 1477770 1478900 R COG0842 ABC-type multidrug transport system, permease component; hypothetical protein complement(1477770..1478900) Helicobacter pylori Shi470 6296842 YP_001910945.1 CDS HPSH_07620 NC_010698.2 1478897 1479985 R COG0842 ABC-type multidrug transport system, permease component; hypothetical protein complement(1478897..1479985) Helicobacter pylori Shi470 6296694 YP_001910946.1 CDS HPSH_07625 NC_010698.2 1480006 1480995 R COG0845 Membrane-fusion protein; hypothetical protein complement(1480006..1480995) Helicobacter pylori Shi470 6296693 YP_001910947.1 CDS HPSH_07630 NC_010698.2 1481007 1482539 R COG1538 Outer membrane protein; lipase-like protein complement(1481007..1482539) Helicobacter pylori Shi470 6296692 YP_001910948.1 CDS HPSH_07635 NC_010698.2 1482536 1483885 R COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein complement(1482536..1483885) Helicobacter pylori Shi470 6296691 YP_001910949.1 CDS HPSH_07640 NC_010698.2 1483984 1485585 R COG0306 Phosphate/sulphate permeases; phosphate permease complement(1483984..1485585) Helicobacter pylori Shi470 6296690 YP_001910950.1 CDS HPSH_07645 NC_010698.2 1485725 1485994 D COG0694 Thioredoxin-like proteins and domains; hypothetical protein 1485725..1485994 Helicobacter pylori Shi470 6296689 YP_001910951.1 CDS HPSH_07650 NC_010698.2 1486007 1486618 D hypothetical protein 1486007..1486618 Helicobacter pylori Shi470 6296688 YP_001910952.1 CDS murE NC_010698.2 1486622 1487965 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1486622..1487965 Helicobacter pylori Shi470 6296687 YP_001910953.1 CDS HPSH_07660 NC_010698.2 1487969 1488919 D Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1487969..1488919 Helicobacter pylori Shi470 6296686 YP_001910954.1 CDS HPSH_07665 NC_010698.2 1488974 1489510 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1488974..1489510 Helicobacter pylori Shi470 6296685 YP_001910955.1 CDS HPSH_07670 NC_010698.2 1489520 1490080 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1489520..1490080 Helicobacter pylori Shi470 6296683 YP_001910956.1 CDS HPSH_07675 NC_010698.2 1490135 1491202 D COG0795 Predicted permeases; hypothetical protein 1490135..1491202 Helicobacter pylori Shi470 6296682 YP_001910957.1 CDS HPSH_07690 NC_010698.2 1492300 1492473 D COG0209 Ribonucleotide reductase, alpha subunit; restriction endonuclease 1492300..1492473 Helicobacter pylori Shi470 6296681 YP_001910958.1 CDS HPSH_07705 NC_010698.2 1493654 1493761 R hypothetical protein complement(1493654..1493761) Helicobacter pylori Shi470 6296679 YP_001910959.1 CDS HPSH_07710 NC_010698.2 1493868 1494305 D COG3399 Uncharacterized protein conserved in bacteria; hypothetical protein 1493868..1494305 Helicobacter pylori Shi470 6296678 YP_001910960.1 CDS HPSH_07715 NC_010698.2 1494302 1496638 R COG2217 Cation transport ATPase; putative cation transporting P-type ATPase complement(1494302..1496638) Helicobacter pylori Shi470 6296677 YP_001910961.1 CDS HPSH_07720 NC_010698.2 1496664 1497380 R COG4123 Predicted O-methyltransferase; hypothetical protein complement(1496664..1497380) Helicobacter pylori Shi470 6296676 YP_001910962.1 CDS HPSH_07725 NC_010698.2 1497362 1498396 R COG0117 Pyrimidine deaminase; riboflavin biosynthesis protein RibG complement(1497362..1498396) Helicobacter pylori Shi470 6296695 YP_001910963.1 CDS HPSH_07730 NC_010698.2 1498393 1499619 R COG0786 Na+/glutamate symporter; sodium/glutamate symport carrier protein/glutamate permease complement(1498393..1499619) Helicobacter pylori Shi470 6296674 YP_001910964.1 CDS HPSH_07735 NC_010698.2 1499753 1500904 D COG1748 Saccharopine dehydrogenase and related proteins; ATP-binding protein 1499753..1500904 Helicobacter pylori Shi470 6296673 YP_001910965.1 CDS HPSH_07740 NC_010698.2 1500914 1502290 R COG0348 Polyferredoxin; ferrodoxin-like protein complement(1500914..1502290) Helicobacter pylori Shi470 6296672 YP_001910966.1 CDS HPSH_07745 NC_010698.2 1502270 1503058 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 1502270..1503058 Helicobacter pylori Shi470 6296671 YP_001910967.1 CDS HPSH_07750 NC_010698.2 1503055 1503408 D COG1539 Dihydroneopterin aldolase; dihydroneopterin aldolase 1503055..1503408 Helicobacter pylori Shi470 6296670 YP_001910968.1 CDS HPSH_07755 NC_010698.2 1503392 1503718 D FrpB-like protein 1503392..1503718 Helicobacter pylori Shi470 6296669 YP_001910969.1 CDS HPSH_07770 NC_010698.2 1506690 1507850 D catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1506690..1507850 Helicobacter pylori Shi470 6296668 YP_001910970.1 CDS nusA NC_010698.2 1507938 1509125 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1507938..1509125 Helicobacter pylori Shi470 6296667 YP_001910971.1 CDS HPSH_07780 NC_010698.2 1509259 1509360 D hypothetical protein 1509259..1509360 Helicobacter pylori Shi470 6296666 YP_001910972.1 CDS HPSH_07785 NC_010698.2 1509357 1510115 R hypothetical protein complement(1509357..1510115) Helicobacter pylori Shi470 6296665 YP_001910973.1 CDS HPSH_07790 NC_010698.2 1510105 1510542 R COG3600 Uncharacterized phage-associated protein; phage-associated protein complement(1510105..1510542) Helicobacter pylori Shi470 6296664 YP_001910974.1 CDS HPSH_07795 NC_010698.2 1510751 1512370 R COG3344 Retron-type reverse transcriptase; hypothetical protein complement(1510751..1512370) Helicobacter pylori Shi470 6296663 YP_001910975.1 CDS HPSH_07800 NC_010698.2 1512387 1512911 R hypothetical protein complement(1512387..1512911) Helicobacter pylori Shi470 6296660 YP_001910976.1 CDS HPSH_07805 NC_010698.2 1512912 1516751 R COG1002 Type II restriction enzyme, methylase subunits; putative type II DNA modification enzyme methyltransferase complement(1512912..1516751) Helicobacter pylori Shi470 6296659 YP_001910977.1 CDS HPSH_07810 NC_010698.2 1516857 1519772 R COG3587 Restriction endonuclease; type III restriction enzyme complement(1516857..1519772) Helicobacter pylori Shi470 6296658 YP_001910978.1 CDS HPSH_07815 NC_010698.2 1519775 1521676 R COG2189 Adenine specific DNA methylase Mod; type III DNA modification methyltransferase complement(1519775..1521676) Helicobacter pylori Shi470 6296657 YP_001910979.1 CDS HPSH_07820 NC_010698.2 1521719 1523590 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1521719..1523590) Helicobacter pylori Shi470 6296542 YP_001910980.1 CDS HPSH_07825 NC_010698.2 1523672 1524016 D hypothetical protein 1523672..1524016 Helicobacter pylori Shi470 6296758 YP_001910981.1 CDS HPSH_07830 NC_010698.2 1524020 1524655 D hypothetical protein 1524020..1524655 Helicobacter pylori Shi470 6296742 YP_001910982.1 CDS HPSH_07835 NC_010698.2 1524652 1525404 R AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III complement(1524652..1525404) Helicobacter pylori Shi470 6296655 YP_001910983.1 CDS HPSH_07840 NC_010698.2 1525582 1527021 R periplasmic competence protein complement(1525582..1527021) Helicobacter pylori Shi470 6296653 YP_001910985.1 CDS HPSH_07850 NC_010698.2 1527148 1527222 D hypothetical protein 1527148..1527222 Helicobacter pylori Shi470 6296648 YP_001910986.1 CDS dnaA NC_010698.2 1527250 1528617 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(1527250..1528617) Helicobacter pylori Shi470 6296647 YP_001910987.1 CDS HPSH_07860 NC_010698.2 1528725 1529312 D COG0813 Purine-nucleoside phosphorylase; purine nucleoside phosphorylase 1528725..1529312 Helicobacter pylori Shi470 6296646 YP_001910988.1 CDS HPSH_07865 NC_010698.2 1529348 1529587 D hypothetical protein 1529348..1529587 Helicobacter pylori Shi470 6296645 YP_001910989.1 CDS HPSH_07870 NC_010698.2 1529588 1531381 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1529588..1531381 Helicobacter pylori Shi470 6296644 YP_001910990.1 CDS thyX NC_010698.2 1531402 1532028 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1531402..1532028 Helicobacter pylori Shi470 6296643 YP_001910991.1 CDS HPSH_07880 NC_010698.2 1532451 1532543 D hypothetical protein 1532451..1532543 Helicobacter pylori Shi470 6296642 YP_001910992.1 CDS HPSH_07885 NC_010698.2 1532623 1533750 R COG0732 Restriction endonuclease S subunits; type I R-M system specificity subunit complement(1532623..1533750) Helicobacter pylori Shi470 6296641 YP_001910993.1 CDS HPSH_07890 NC_010698.2 1533747 1536209 R COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme M protein HsdM complement(1533747..1536209) Helicobacter pylori Shi470 6296640 YP_001910994.1 CDS HPSH_07895 NC_010698.2 1536280 1539255 D COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme R protein HsdR 1536280..1539255 Helicobacter pylori Shi470 6296638 YP_001910995.1 CDS HPSH_07900 NC_010698.2 1539255 1539962 D COG1451 Predicted metal-dependent hydrolase; hypothetical protein 1539255..1539962 Helicobacter pylori Shi470 6296636 YP_001910996.1 CDS HPSH_07905 NC_010698.2 1540052 1542577 R COG1629 Outer membrane receptor proteins, mostly Fe transport; iron(III dicitrate transport protein FecA complement(1540052..1542577) Helicobacter pylori Shi470 6296822 YP_001910997.1 CDS HPSH_07910 NC_010698.2 1542938 1543096 D hypothetical protein 1542938..1543096 Helicobacter pylori Shi470 6296632 YP_001910998.1 CDS HPSH_07915 NC_010698.2 1543152 1544087 R COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; arginase RocF complement(1543152..1544087) Helicobacter pylori Shi470 6296631 YP_001910999.1 CDS HPSH_07920 NC_010698.2 1544291 1545433 D COG0686 Alanine dehydrogenase; alanine dehydrogenase 1544291..1545433 Helicobacter pylori Shi470 6296630 YP_001911000.1 CDS HPSH_07925 NC_010698.2 1545551 1547248 D COG1479 Uncharacterized conserved protein; hypothetical protein 1545551..1547248 Helicobacter pylori Shi470 6296629 YP_001911001.1 CDS HPSH_07930 NC_010698.2 1547259 1547987 R putative outer membrane protein complement(1547259..1547987) Helicobacter pylori Shi470 6296628 YP_001911002.1 CDS HPSH_07935 NC_010698.2 1548173 1549027 D COG0061 Predicted sugar kinase; inorganic polyphosphate/ATP-NAD kinase 1548173..1549027 Helicobacter pylori Shi470 6296627 YP_001911003.1 CDS HPSH_07940 NC_010698.2 1549040 1550614 D COG0497 ATPase involved in DNA repair; DNA repair protein 1549040..1550614 Helicobacter pylori Shi470 6296626 YP_001911004.1 CDS HPSH_07945 NC_010698.2 1550611 1551918 D COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; fibronectin/fibrinogen-binding protein 1550611..1551918 Helicobacter pylori Shi470 6296625 YP_001911005.1 CDS HPSH_07950 NC_010698.2 1551937 1552233 D hypothetical protein 1551937..1552233 Helicobacter pylori Shi470 6296624 YP_001911006.1 CDS HPSH_07955 NC_010698.2 1552564 1552884 D hypothetical protein 1552564..1552884 Helicobacter pylori Shi470 6296623 YP_001911007.1 CDS HPSH_07960 NC_010698.2 1552923 1553252 D hypothetical protein 1552923..1553252 Helicobacter pylori Shi470 6296622 YP_001911008.1 CDS HPSH_07965 NC_010698.2 1553351 1553548 D hypothetical protein 1553351..1553548 Helicobacter pylori Shi470 6296620 YP_001911009.1 CDS HPSH_07970 NC_010698.2 1553522 1554385 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1553522..1554385) Helicobacter pylori Shi470 6296619 YP_001911010.1 CDS HPSH_07975 NC_010698.2 1554363 1555016 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(1554363..1555016) Helicobacter pylori Shi470 6296618 YP_001911011.1 CDS HPSH_07980 NC_010698.2 1555087 1555959 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1555087..1555959 Helicobacter pylori Shi470 6296617 YP_001911012.1 CDS HPSH_07985 NC_010698.2 1555959 1556162 D hypothetical protein 1555959..1556162 Helicobacter pylori Shi470 6296514 YP_001911013.1 CDS HPSH_07990 NC_010698.2 1556175 1557071 D COG0827 Adenine-specific DNA methylase; putative type II methylase protein 1556175..1557071 Helicobacter pylori Shi470 6296634 YP_001911014.1 CDS HPSH_07995 NC_010698.2 1557064 1557795 D hypothetical protein 1557064..1557795 Helicobacter pylori Shi470 6296169 YP_001911015.1 CDS HPSH_08000 NC_010698.2 1557885 1558337 R hypothetical protein complement(1557885..1558337) Helicobacter pylori Shi470 6296616 YP_001911016.1 CDS tsf NC_010698.2 1558389 1559456 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1558389..1559456) Helicobacter pylori Shi470 6296612 YP_001911017.1 CDS rpsB NC_010698.2 1559456 1560250 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1559456..1560250) Helicobacter pylori Shi470 6296609 YP_001911018.1 CDS HPSH_08015 NC_010698.2 1560343 1560429 D hypothetical protein 1560343..1560429 Helicobacter pylori Shi470 6296608 YP_001911019.1 CDS HPSH_08020 NC_010698.2 1560501 1563350 D COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); putative recombination protein RecB 1560501..1563350 Helicobacter pylori Shi470 6296607 YP_001911020.1 CDS nhaA NC_010698.2 1563341 1564690 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1563341..1564690 Helicobacter pylori Shi470 6296606 YP_001911021.1 CDS yajC NC_010698.2 1564738 1565031 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1564738..1565031 Helicobacter pylori Shi470 6296605 YP_001911022.1 CDS secD NC_010698.2 1565031 1566608 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1565031..1566608 Helicobacter pylori Shi470 6296603 YP_001911023.1 CDS secF NC_010698.2 1566617 1567588 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1566617..1567588 Helicobacter pylori Shi470 6296601 YP_001911024.1 CDS HPSH_08045 NC_010698.2 1567598 1567936 D hypothetical protein 1567598..1567936 Helicobacter pylori Shi470 6296600 YP_001911025.1 CDS leuS NC_010698.2 1567946 1570366 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1567946..1570366 Helicobacter pylori Shi470 6296599 YP_001911026.1 CDS HPSH_08055 NC_010698.2 1570363 1570875 D hypothetical protein 1570363..1570875 Helicobacter pylori Shi470 6296598 YP_001911027.1 CDS HPSH_08060 NC_010698.2 1570865 1572034 D COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 1570865..1572034 Helicobacter pylori Shi470 6296597 YP_002154435.1 CDS HPSH_08065 NC_010698.2 1572034 1572960 D tox-R activated gene 1572034..1572960 Helicobacter pylori Shi470 6972668 YP_001911028.1 CDS HPSH_08075 NC_010698.2 1572969 1573904 D COG0739 Membrane proteins related to metalloendopeptidases; toxR-activated gene TagE 1572969..1573904 Helicobacter pylori Shi470 6296596 YP_001911029.1 CDS HPSH_08080 NC_010698.2 1573919 1574233 D COG1664 Integral membrane protein CcmA involved in cell shape determination; hypothetical protein 1573919..1574233 Helicobacter pylori Shi470 6296595 YP_001911030.1 CDS HPSH_08085 NC_010698.2 1574237 1577236 D COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 1574237..1577236 Helicobacter pylori Shi470 6296594 YP_001911031.1 CDS HPSH_08090 NC_010698.2 1577361 1577864 D COG0723 Rieske Fe-S protein; ubiquinol cytochrome c oxidoreductase, Rieske 2Fe-2S subunit FbcF 1577361..1577864 Helicobacter pylori Shi470 6296592 YP_001911032.1 CDS HPSH_08095 NC_010698.2 1577875 1579113 D COG1290 Cytochrome b subunit of the bc complex; ubiquinol cytochrome c oxidoreductase, cytochrome b subunit FbcH 1577875..1579113 Helicobacter pylori Shi470 6296591 YP_001911033.1 CDS HPSH_08100 NC_010698.2 1579110 1579967 D COG2857 Cytochrome c1; ubiquinol cytochrome c oxidoreductase, cytochrome c1 1579110..1579967 Helicobacter pylori Shi470 6296738 YP_001911034.1 CDS HPSH_08105 NC_010698.2 1580172 1580507 R hypothetical protein complement(1580172..1580507) Helicobacter pylori Shi470 6296589 YP_001911035.1 CDS HPSH_08110 NC_010698.2 1580949 1582796 R COG0768 Cell division protein FtsI/penicillin-binding protein 2; cell division protein complement(1580949..1582796) Helicobacter pylori Shi470 6296587 YP_001911036.1 CDS fliE NC_010698.2 1582952 1583281 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1582952..1583281) Helicobacter pylori Shi470 6296586 YP_001911037.1 CDS flgC NC_010698.2 1583409 1583894 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(1583409..1583894) Helicobacter pylori Shi470 6296584 YP_001911038.1 CDS flgB NC_010698.2 1583907 1584329 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB complement(1583907..1584329) Helicobacter pylori Shi470 6296583 YP_001911039.1 CDS HPSH_08130 NC_010698.2 1584538 1585704 D COG0772 Bacterial cell division membrane protein; putative rod shape-determining protein 1584538..1585704 Helicobacter pylori Shi470 6296581 YP_001911040.1 CDS HPSH_08135 NC_010698.2 1585728 1586729 R COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; hypothetical protein complement(1585728..1586729) Helicobacter pylori Shi470 6296580 YP_001911041.1 CDS HPSH_08140 NC_010698.2 1586928 1587935 R COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; iron(III ABC transporter periplasmic iron-binding protein CeuE complement(1586928..1587935) Helicobacter pylori Shi470 6296579 YP_001911042.1 CDS HPSH_08145 NC_010698.2 1588174 1588770 D COG0450 Peroxiredoxin; putative peroxidase 1588174..1588770 Helicobacter pylori Shi470 6296577 YP_001911043.1 CDS HPSH_08150 NC_010698.2 1588915 1589730 D COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; outer membrane protein 1588915..1589730 Helicobacter pylori Shi470 6296576 YP_001911044.1 CDS HPSH_08155 NC_010698.2 1589798 1591573 R COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 2 (pbp2) complement(1589798..1591573) Helicobacter pylori Shi470 6296575 YP_001911045.1 CDS HPSH_08160 NC_010698.2 1591554 1591997 R hypothetical protein complement(1591554..1591997) Helicobacter pylori Shi470 6296574 YP_001911046.1 CDS engB NC_010698.2 1592010 1592636 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1592010..1592636) Helicobacter pylori Shi470 6296573 YP_001911047.1 CDS HPSH_08170 NC_010698.2 1592633 1593190 R COG1934 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1592633..1593190) Helicobacter pylori Shi470 6296567 YP_001911048.1 CDS HPSH_08175 NC_010698.2 1593190 1593783 R hypothetical protein complement(1593190..1593783) Helicobacter pylori Shi470 6296566 YP_001911049.1 CDS HPSH_08180 NC_010698.2 1593758 1594252 R COG1778 Low specificity phosphatase (HAD superfamily); hypothetical protein complement(1593758..1594252) Helicobacter pylori Shi470 6296533 YP_001911050.1 CDS HPSH_08185 NC_010698.2 1594249 1595196 R COG0797 Lipoproteins; rare lipoprotein A RlpA complement(1594249..1595196) Helicobacter pylori Shi470 6296713 YP_001911051.1 CDS HPSH_08190 NC_010698.2 1595196 1596308 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); putative regulatory protein complement(1595196..1596308) Helicobacter pylori Shi470 6296375 YP_001911052.1 CDS HPSH_08195 NC_010698.2 1596409 1597173 R COG0084 Mg-dependent DNase; DNAse complement(1596409..1597173) Helicobacter pylori Shi470 6296563 YP_001911053.1 CDS HPSH_08200 NC_010698.2 1597248 1597868 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1597248..1597868 Helicobacter pylori Shi470 6296562 YP_001911054.1 CDS HPSH_08205 NC_010698.2 1597869 1598141 D COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB; FlhB-related flagellar biosynthesis protein 1597869..1598141 Helicobacter pylori Shi470 6296561 YP_001911055.1 CDS metN NC_010698.2 1598163 1599146 D part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 1598163..1599146 Helicobacter pylori Shi470 6296560 YP_001911056.1 CDS HPSH_08215 NC_010698.2 1599148 1599795 D COG2011 ABC-type metal ion transport system, permease component; ABC transporter permease 1599148..1599795 Helicobacter pylori Shi470 6296558 YP_001911057.1 CDS HPSH_08220 NC_010698.2 1599984 1600415 R hypothetical protein complement(1599984..1600415) Helicobacter pylori Shi470 6296557 YP_001911058.1 CDS HPSH_08225 NC_010698.2 1600425 1601021 R COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein complement(1600425..1601021) Helicobacter pylori Shi470 6296556 YP_001911059.1 CDS HPSH_08230 NC_010698.2 1601021 1602019 R COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; undecaprenyl phosphate N-acetylglucosaminyltransferase complement(1601021..1602019) Helicobacter pylori Shi470 6296555 YP_001911060.1 CDS HPSH_08235 NC_010698.2 1602164 1602952 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1602164..1602952 Helicobacter pylori Shi470 6296554 YP_001911061.1 CDS pdxA NC_010698.2 1602954 1603877 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1602954..1603877 Helicobacter pylori Shi470 6296553 YP_001911062.1 CDS HPSH_08245 NC_010698.2 1603941 1604963 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1603941..1604963 Helicobacter pylori Shi470 6296552 YP_001911063.1 CDS flgG NC_010698.2 1605142 1605930 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1605142..1605930 Helicobacter pylori Shi470 6296550 YP_001911064.1 CDS HPSH_08265 NC_010698.2 1606736 1606873 R hypothetical protein complement(1606736..1606873) Helicobacter pylori Shi470 6296549 YP_001911065.1 CDS HPSH_08270 NC_010698.2 1607319 1607459 R hypothetical protein complement(1607319..1607459) Helicobacter pylori Shi470 6296545 YP_001911066.1 CDS HPSH_08275 NC_010698.2 1607544 1608305 R COG4735 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1607544..1608305) Helicobacter pylori Shi470 6296544 HPSH_t08282 tRNA HPSH_t08282 NC_010698.2 4042 4117 R tRNA-Glu complement(4042..4117) Helicobacter pylori Shi470 6296017 HPSH_t08284 tRNA HPSH_t08284 NC_010698.2 4181 4257 R tRNA-Asp complement(4181..4257) Helicobacter pylori Shi470 6296611 HPSH_t08286 tRNA HPSH_t08286 NC_010698.2 4298 4373 R tRNA-Val complement(4298..4373) Helicobacter pylori Shi470 6297409 HPSH_t08288 tRNA HPSH_t08288 NC_010698.2 4415 4489 R tRNA-Glu complement(4415..4489) Helicobacter pylori Shi470 6296385 HPSH_t08290 tRNA HPSH_t08290 NC_010698.2 4500 4575 R tRNA-Lys complement(4500..4575) Helicobacter pylori Shi470 6296527 HPSH_t08292 tRNA HPSH_t08292 NC_010698.2 66019 66094 R tRNA-Val complement(66019..66094) Helicobacter pylori Shi470 6296726 HPSH_t08294 tRNA HPSH_t08294 NC_010698.2 83996 84087 D tRNA-Ser 83996..84087 Helicobacter pylori Shi470 6296933 HPSH_t08296 tRNA HPSH_t08296 NC_010698.2 223521 223595 R tRNA-Asn complement(223521..223595) Helicobacter pylori Shi470 6296615 HPSH_t08298 tRNA HPSH_t08298 NC_010698.2 246217 246292 R tRNA-Ala complement(246217..246292) Helicobacter pylori Shi470 6296207 HPSH_t08300 tRNA HPSH_t08300 NC_010698.2 328296 328372 D tRNA-Arg 328296..328372 Helicobacter pylori Shi470 6297116 HPSH_t08302 tRNA HPSH_t08302 NC_010698.2 381387 381474 R tRNA-Ser complement(381387..381474) Helicobacter pylori Shi470 6296180 HPSH_t08304 tRNA HPSH_t08304 NC_010698.2 432011 432088 R tRNA-Pro complement(432011..432088) Helicobacter pylori Shi470 6296335 HPSH_t08306 tRNA HPSH_t08306 NC_010698.2 509102 509178 R tRNA-Arg complement(509102..509178) Helicobacter pylori Shi470 6296132 HPSH_t08308 tRNA HPSH_t08308 NC_010698.2 596997 597073 D tRNA-Met 596997..597073 Helicobacter pylori Shi470 6296083 HPSH_t08310 tRNA HPSH_t08310 NC_010698.2 932131 932207 R tRNA-Met complement(932131..932207) Helicobacter pylori Shi470 6297442 HPSH_t08312 tRNA HPSH_t08312 NC_010698.2 932239 932313 R tRNA-Gln complement(932239..932313) Helicobacter pylori Shi470 6297441 HPSH_t08314 tRNA HPSH_t08314 NC_010698.2 987504 987578 D tRNA-Gly 987504..987578 Helicobacter pylori Shi470 6297391 HPSH_t08316 tRNA HPSH_t08316 NC_010698.2 987974 988060 D tRNA-Leu 987974..988060 Helicobacter pylori Shi470 6297389 HPSH_t08318 tRNA HPSH_t08318 NC_010698.2 988135 988209 D tRNA-Cys 988135..988209 Helicobacter pylori Shi470 6297387 HPSH_t08320 tRNA HPSH_t08320 NC_010698.2 988257 988344 D tRNA-Ser 988257..988344 Helicobacter pylori Shi470 6297386 HPSH_t08322 tRNA HPSH_t08322 NC_010698.2 1053599 1053675 R tRNA-Arg complement(1053599..1053675) Helicobacter pylori Shi470 6297337 HPSH_t08324 tRNA HPSH_t08324 NC_010698.2 1053693 1053769 R tRNA-Arg complement(1053693..1053769) Helicobacter pylori Shi470 6296769 HPSH_t08326 tRNA HPSH_t08326 NC_010698.2 1053830 1053906 R tRNA-His complement(1053830..1053906) Helicobacter pylori Shi470 6297311 HPSH_t08328 tRNA HPSH_t08328 NC_010698.2 1053974 1054051 R tRNA-Pro complement(1053974..1054051) Helicobacter pylori Shi470 6297309 HPSH_t08330 tRNA HPSH_t08330 NC_010698.2 1104045 1104129 R tRNA-Leu complement(1104045..1104129) Helicobacter pylori Shi470 6297240 HPSH_t08332 tRNA HPSH_t08332 NC_010698.2 1108914 1108990 D tRNA-Ile 1108914..1108990 Helicobacter pylori Shi470 6297232 HPSH_t08334 tRNA HPSH_t08334 NC_010698.2 1109005 1109080 D tRNA-Ala 1109005..1109080 Helicobacter pylori Shi470 6297231 HPSH_t08336 tRNA HPSH_t08336 NC_010698.2 1201174 1201251 R tRNA-Met complement(1201174..1201251) Helicobacter pylori Shi470 6297314 HPSH_t08338 tRNA HPSH_t08338 NC_010698.2 1230290 1230365 R tRNA-Trp complement(1230290..1230365) Helicobacter pylori Shi470 6297056 HPSH_t08340 tRNA HPSH_t08340 NC_010698.2 1231923 1231997 R tRNA-Thr complement(1231923..1231997) Helicobacter pylori Shi470 6297053 HPSH_t08342 tRNA HPSH_t08342 NC_010698.2 1232028 1232104 R tRNA-Gly complement(1232028..1232104) Helicobacter pylori Shi470 6297052 HPSH_t08344 tRNA HPSH_t08344 NC_010698.2 1232120 1232204 R tRNA-Tyr complement(1232120..1232204) Helicobacter pylori Shi470 6297051 HPSH_t08346 tRNA HPSH_t08346 NC_010698.2 1232232 1232307 R tRNA-Thr complement(1232232..1232307) Helicobacter pylori Shi470 6297050 HPSH_t08348 tRNA HPSH_t08348 NC_010698.2 1237617 1237703 R tRNA-Leu complement(1237617..1237703) Helicobacter pylori Shi470 6297034 HPSH_t08350 tRNA HPSH_t08350 NC_010698.2 1237759 1237845 R tRNA-Leu complement(1237759..1237845) Helicobacter pylori Shi470 6297032 HPSH_t08352 tRNA HPSH_t08352 NC_010698.2 1525504 1525579 D tRNA-Phe 1525504..1525579 Helicobacter pylori Shi470 6296654 HPSH_r08354 rRNA HPSH_r08354 NC_010698.2 1032702 1032819 R 5S ribosomal RNA complement(1032702..1032819) Helicobacter pylori Shi470 6297333 HPSH_r08362 rRNA HPSH_r08362 NC_010698.2 1033056 1035937 R 23S ribosomal RNA complement(1033056..1035937) Helicobacter pylori Shi470 6297331 HPSH_r08358 rRNA HPSH_r08358 NC_010698.2 1160078 1161586 R 16S ribosomal RNA complement(1160078..1161586) Helicobacter pylori Shi470 6297161 HPSH_r08356 rRNA HPSH_r08356 NC_010698.2 1399071 1399188 R 5S ribosomal RNA complement(1399071..1399188) Helicobacter pylori Shi470 6296795 HPSH_r08364 rRNA HPSH_r08364 NC_010698.2 1399425 1402306 R 23S ribosomal RNA complement(1399425..1402306) Helicobacter pylori Shi470 6296794 HPSH_r08360 rRNA HPSH_r08360 NC_010698.2 1430990 1432498 R 16S ribosomal RNA complement(1430990..1432498) Helicobacter pylori Shi470 6296752