-- dump date   	20140619_114207
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_001909500.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_001909501.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_001909502.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_001909503.1	COG0288 Carbonic anhydrase
YP_001909504.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_001909505.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_001909507.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_001909508.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_001909509.1	synthesizes RNA primers at the replication forks
YP_001909510.1	COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
YP_001909515.1	COG3451 Type IV secretory pathway, VirB4 components
YP_001909516.1	COG3014 Uncharacterized protein conserved in bacteria
YP_001909517.1	COG0835 Chemotaxis signal transduction protein
YP_001909518.1	COG0019 Diaminopimelate decarboxylase
YP_001909519.1	inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022
YP_001909520.1	attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria
YP_001909523.1	type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH
YP_001909524.1	COG0538 Isocitrate dehydrogenases
YP_001909526.1	COG0132 Dethiobiotin synthetase
YP_001909528.1	COG0589 Universal stress protein UspA and related nucleotide-binding proteins
YP_001909529.1	COG2127 Uncharacterized conserved protein
YP_001909530.1	COG0542 ATPases with chaperone activity, ATP-binding subunit
YP_001909531.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_001909532.1	COG0718 Uncharacterized protein conserved in bacteria
YP_001909533.1	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YP_001909536.1	COG3736 Type IV secretory pathway, component VirB8
YP_001909537.1	COG3504 Type IV secretory pathway, VirB9 components
YP_001909538.1	COG2948 Type IV secretory pathway, VirB10 components
YP_001909539.1	COG0836 Mannose-1-phosphate guanylyltransferase
YP_001909540.1	COG1089 GDP-D-mannose dehydratase
YP_001909541.1	COG0451 Nucleoside-diphosphate-sugar epimerases
YP_001909543.1	COG0309 Hydrogenase maturation factor
YP_001909544.1	COG0068 Hydrogenase maturation factor
YP_001909545.1	COG2957 Peptidylarginine deiminase and related enzymes
YP_001909546.1	COG0863 DNA modification methylase
YP_001909547.1	COG0270 Site-specific DNA methylase
YP_001909551.1	COG0591 Na+/proline symporter
YP_001909552.1	COG0506 Proline dehydrogenase
YP_001909556.1	COG5002 Signal transduction histidine kinase
YP_001909559.1	COG0829 Urease accessory protein UreH
YP_001909560.1	COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
YP_001909561.1	COG0830 Urease accessory protein UreF
YP_001909562.1	involved in the assembly of the urease metallocenter; possible nickel donor
YP_001909563.1	COG1138 Cytochrome c biogenesis factor
YP_001909565.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits
YP_001909566.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits
YP_001909567.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_001909568.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_001909569.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001909570.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_001909575.1	COG0840 Methyl-accepting chemotaxis protein
YP_001909576.1	forms a direct contact with the tRNA during translation
YP_001909577.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_001909580.1	COG0579 Predicted dehydrogenase
YP_001909581.1	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
YP_001909582.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_001909583.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_001909584.1	COG0331 (acyl-carrier-protein) S-malonyltransferase
YP_001909585.1	COG0863 DNA modification methylase
YP_001909588.1	Involved in the metabolism of aromatic amino acids
YP_001909590.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_001909591.1	COG0840 Methyl-accepting chemotaxis protein
YP_001909592.1	COG1636 Uncharacterized protein conserved in bacteria
YP_001909594.1	COG0463 Glycosyltransferases involved in cell wall biogenesis
YP_001909595.1	COG0840 Methyl-accepting chemotaxis protein
YP_001909596.1	COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
YP_001909597.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_001909598.1	catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine
YP_001909599.1	COG0031 Cysteine synthase
YP_001909600.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_001909601.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_001909602.1	Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction
YP_001909603.1	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
YP_001909605.1	COG2604 Uncharacterized protein conserved in bacteria
YP_001909606.1	FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions
YP_001909607.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_001909608.1	COG0731 Fe-S oxidoreductases
YP_001909611.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_001909613.1	catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001909614.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_001909615.1	COG0291 Ribosomal protein L35
YP_001909616.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_001909622.1	COG1760 L-serine deaminase
YP_001909623.1	COG0814 Amino acid permeases
YP_001909625.1	COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
YP_001909627.1	COG1225 Peroxiredoxin
YP_001909628.1	COG1556 Uncharacterized conserved protein
YP_001909629.1	COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
YP_001909630.1	COG0247 Fe-S oxidoreductase
YP_001909631.1	COG1620 L-lactate permease
YP_001909632.1	COG1620 L-lactate permease
YP_001909633.1	COG1194 A/G-specific DNA glycosylase
YP_001909634.1	COG0471 Di- and tricarboxylate transporters
YP_001909635.1	CcoN; FixN
YP_001909636.1	CcoO; FixO
YP_001909638.1	COG2010 Cytochrome c, mono- and diheme variants
YP_001909641.1	COG0443 Molecular chaperone
YP_001909644.1	COG2107 Predicted periplasmic solute-binding protein
YP_001909645.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_001909646.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_001909649.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_001909651.1	COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
YP_001909652.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001909654.1	COG0217 Uncharacterized conserved protein
YP_001909655.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_001909656.1	COG0642 Signal transduction histidine kinase
YP_001909657.1	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001909659.1	COG0457 FOG: TPR repeat
YP_001909660.1	COG0826 Collagenase and related proteases
YP_001909662.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_001909663.1	COG0303 Molybdopterin biosynthesis enzyme
YP_001909664.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
YP_001909666.1	COG0760 Parvulin-like peptidyl-prolyl isomerase
YP_001909667.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_001909668.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_001909670.1	COG2089 Sialic acid synthase
YP_001909671.1	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
YP_001909672.1	Transfers the fatty acyl group on membrane lipoproteins
YP_001909674.1	COG1286 Uncharacterized membrane protein, required for colicin V production
YP_001909675.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_001909676.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_001909680.1	COG1479 Uncharacterized conserved protein
YP_001909681.1	COG2862 Predicted membrane protein
YP_001909682.1	COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes
YP_001909683.1	part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_001909684.1	part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_001909685.1	part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit
YP_001909686.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_001909687.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_001909688.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_001909689.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_001909690.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_001909692.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_001909693.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_001909694.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_001909697.1	COG0489 ATPases involved in chromosome partitioning
YP_001909698.1	COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
YP_001909701.1	molecular chaperone
YP_001909702.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001909703.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_001909704.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_001909705.1	COG0471 Di- and tricarboxylate transporters
YP_001909706.1	COG0575 CDP-diglyceride synthetase
YP_001909707.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_001909710.1	COG1881 Phospholipid-binding protein
YP_001909712.1	COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
YP_001909713.1	COG0822 NifU homolog involved in Fe-S cluster formation
YP_001909715.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_001909716.1	COG0225 Peptide methionine sulfoxide reductase
YP_001909718.1	COG0730 Predicted permeases
YP_001909721.1	COG0659 Sulfate permease and related transporters (MFS superfamily)
YP_001909723.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_001909724.1	COG1651 Protein-disulfide isomerase
YP_001909726.1	COG0754 Glutathionylspermidine synthase
YP_001909729.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001909731.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_001909732.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_001909733.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_001909734.1	COG0142 Geranylgeranyl pyrophosphate synthase
YP_001909737.1	COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
YP_001909738.1	COG0642 Signal transduction histidine kinase
YP_001909740.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum
YP_001909741.1	COG0513 Superfamily II DNA and RNA helicases
YP_001909742.1	COG0330 Membrane protease subunits, stomatin/prohibitin homologs
YP_001909744.1	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
YP_001909745.1	COG4239 ABC-type uncharacterized transport system, permease component
YP_001909749.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_001909751.1	COG3334 Uncharacterized conserved protein
YP_001909752.1	COG0750 Predicted membrane-associated Zn-dependent proteases 1
YP_001909753.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_001909754.1	COG2189 Adenine specific DNA methylase Mod
YP_001909756.1	COG0863 DNA modification methylase
YP_001909757.1	COG0542 ATPases with chaperone activity, ATP-binding subunit
YP_001909758.1	COG0785 Cytochrome c biogenesis protein
YP_001909759.1	COG0044 Dihydroorotase and related cyclic amidohydrolases
YP_001909760.1	Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline
YP_001909762.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_001909763.1	COG2121 Uncharacterized protein conserved in bacteria
YP_001909767.1	COG0727 Predicted Fe-S-cluster oxidoreductase
YP_001909768.1	COG0457 FOG: TPR repeat
YP_001909769.1	COG0134 Indole-3-glycerol phosphate synthase
YP_001909770.1	COG1145 Ferredoxin
YP_001909771.1	COG0248 Exopolyphosphatase
YP_001909772.1	COG0859 ADP-heptose:LPS heptosyltransferase
YP_001909773.1	acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes
YP_001909774.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_001909775.1	COG3400 Uncharacterized protein conserved in bacteria
YP_001909776.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_001909777.1	COG0668 Small-conductance mechanosensitive channel
YP_001909778.1	COG0621 2-methylthioadenine synthetase
YP_001909779.1	COG0465 ATP-dependent Zn proteases
YP_001909783.1	COG0019 Diaminopimelate decarboxylase
YP_001909784.1	COG1605 Chorismate mutase
YP_001909785.1	COG4866 Uncharacterized conserved protein
YP_001909786.1	COG0147 Anthranilate/para-aminobenzoate synthases component I
YP_001909787.1	aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates
YP_001909788.1	with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook
YP_001909789.1	COG0261 Ribosomal protein L21
YP_001909790.1	involved in the peptidyltransferase reaction during translation
YP_001909791.1	COG0747 ABC-type dipeptide transport system, periplasmic component
YP_001909792.1	COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
YP_001909793.1	COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
YP_001909794.1	COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
YP_001909795.1	COG4608 ABC-type oligopeptide transport system, ATPase component
YP_001909796.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_001909799.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_001909802.1	COG0388 Predicted amidohydrolase
YP_001909804.1	COG0863 DNA modification methylase
YP_001909806.1	COG0523 Putative GTPases (G3E family)
YP_001909807.1	COG0477 Permeases of the major facilitator superfamily
YP_001909809.1	COG0748 Putative heme iron utilization protein
YP_001909810.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_001909811.1	COG1826 Sec-independent protein secretion pathway components
YP_001909812.1	Essential for recycling GMP and indirectly, cGMP
YP_001909815.1	membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation
YP_001909817.1	part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod
YP_001909818.1	COG1083 CMP-N-acetylneuraminic acid synthetase
YP_001909819.1	COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase
YP_001909820.1	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
YP_001909821.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
YP_001909822.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_001909823.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_001909824.1	COG2894 Septum formation inhibitor-activating ATPase
YP_001909825.1	works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell
YP_001909826.1	COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
YP_001909827.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_001909829.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001909836.1	COG3326 Predicted membrane protein
YP_001909839.1	COG0564 Pseudouridylate synthases, 23S RNA-specific
YP_001909840.1	COG0608 Single-stranded DNA-specific exonuclease
YP_001909841.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_001909842.1	COG0671 Membrane-associated phospholipid phosphatase
YP_001909843.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_001909844.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_001909845.1	binds to and inhibits the function of flagella specific ATPase FliI
YP_001909846.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_001909847.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_001909848.1	COG0270 Site-specific DNA methylase
YP_001909850.1	COG4786 Flagellar basal body rod protein
YP_001909851.1	COG0477 Permeases of the major facilitator superfamily
YP_001909852.1	COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
YP_001909853.1	COG3893 Inactivated superfamily I helicase
YP_001909854.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_001909855.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_001909856.1	COG1189 Predicted rRNA methylase
YP_001909858.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_001909861.1	COG1132 ABC-type multidrug transport system, ATPase and permease components
YP_001909863.1	COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes
YP_001909864.1	COG1106 Predicted ATPases
YP_001909866.1	COG3376 High-affinity nickel permease
YP_001909872.1	COG2608 Copper chaperone
YP_001909873.1	COG2217 Cation transport ATPase
YP_001909874.1	COG1183 Phosphatidylserine synthase
YP_001909875.1	COG0465 ATP-dependent Zn proteases
YP_001909876.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_001909877.1	COG0784 FOG: CheY-like receiver
YP_001909881.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_001909882.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_001909883.1	COG0805 Sec-independent protein secretion pathway component TatC
YP_001909884.1	mediates the export of protein precursors bearing twin-arginine signal peptides
YP_001909885.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_001909886.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_001909890.1	COG0739 Membrane proteins related to metalloendopeptidases
YP_001909891.1	blocks the formation of polar Z-ring septums
YP_001909892.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
YP_001909893.1	COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
YP_001909894.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_001909895.1	COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination
YP_001909896.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_001909897.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_001909898.1	COG0779 Uncharacterized protein conserved in bacteria
YP_001909899.1	COG1408 Predicted phosphohydrolases
YP_001909900.1	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001909901.1	COG2404 Predicted phosphohydrolase (DHH superfamily)
YP_001909902.1	membrane protein involved in the flagellar export apparatus
YP_001909903.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_001909904.1	COG3307 Lipid A core - O-antigen ligase and related enzymes
YP_001909905.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
YP_001909906.1	COG0006 Xaa-Pro aminopeptidase
YP_001909907.1	COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
YP_001909908.1	positive regulator of class III flagellar genes
YP_001909909.1	COG0455 ATPases involved in chromosome partitioning
YP_001909911.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes
YP_001909912.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
YP_001909913.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_001909914.1	COG2731 Beta-galactosidase, beta subunit
YP_001909915.1	COG4731 Uncharacterized protein conserved in bacteria
YP_001909916.1	COG0735 Fe2+/Zn2+ uptake regulation proteins
YP_001909917.1	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
YP_001909918.1	COG0789 Predicted transcriptional regulators
YP_001909919.1	COG2214 DnaJ-class molecular chaperone
YP_001909921.1	COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
YP_001909922.1	COG0784 FOG: CheY-like receiver
YP_001909923.1	bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations
YP_001909924.1	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YP_001909925.1	COG0833 Amino acid transporters
YP_001909926.1	COG0558 Phosphatidylglycerophosphate synthase
YP_001909928.1	Acts on the hydroxyl group at position 7 of the steroid frame
YP_001909929.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_001909930.1	COG0612 Predicted Zn-dependent peptidases
YP_001909931.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_001909932.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_001909933.1	COG0732 Restriction endonuclease S subunits
YP_001909934.1	COG0286 Type I restriction-modification system methyltransferase subunit
YP_001909935.1	COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
YP_001909936.1	COG2604 Uncharacterized protein conserved in bacteria
YP_001909939.1	COG2048 Heterodisulfide reductase, subunit B
YP_001909941.1	COG1164 Oligoendopeptidase F
YP_001909942.1	COG0475 Kef-type K+ transport systems, membrane components
YP_001909946.1	COG0725 ABC-type molybdate transport system, periplasmic component
YP_001909947.1	COG4149 ABC-type molybdate transport system, permease component
YP_001909948.1	COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
YP_001909949.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_001909951.1	COG0286 Type I restriction-modification system methyltransferase subunit
YP_001909952.1	COG1217 Predicted membrane GTPase involved in stress response
YP_001909953.1	COG0338 Site-specific DNA methylase
YP_001909955.1	COG0270 Site-specific DNA methylase
YP_001909959.1	COG0753 Catalase
YP_001909964.1	COG1432 Uncharacterized conserved protein
YP_001909965.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_001909966.1	COG1629 Outer membrane receptor proteins, mostly Fe transport
YP_001909967.1	COG0753 Catalase
YP_001909970.1	COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
YP_001909971.1	COG2134 CDP-diacylglycerol pyrophosphatase
YP_001909972.1	the hook connects flagellar basal body to the flagellar filament
YP_001909973.1	plays a role in hydrogenase nickel cofactor insertion
YP_001909975.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
YP_001909976.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_001909977.1	catalyzes the formation of dUMP from dUTP
YP_001909980.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_001909981.1	COG2836 Uncharacterized conserved protein
YP_001909982.1	COG0241 Histidinol phosphatase and related phosphatases
YP_001909983.1	COG0451 Nucleoside-diphosphate-sugar epimerases
YP_001909984.1	COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase
YP_001909985.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
YP_001909986.1	COG0516 IMP dehydrogenase/GMP reductase
YP_001909987.1	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
YP_001909988.1	COG2958 Uncharacterized protein conserved in bacteria
YP_001909989.1	COG0671 Membrane-associated phospholipid phosphatase
YP_001909991.1	COG0270 Site-specific DNA methylase
YP_001909992.1	COG0286 Type I restriction-modification system methyltransferase subunit
YP_001909993.1	COG0732 Restriction endonuclease S subunits
YP_001909994.1	COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
YP_001909995.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
YP_001909996.1	COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
YP_001909997.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
YP_001909999.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_001910000.1	COG1086 Predicted nucleoside-diphosphate sugar epimerases
YP_001910001.1	COG2067 Long-chain fatty acid transport protein
YP_001910003.1	COG3018 Uncharacterized protein conserved in bacteria
YP_001910005.1	COG0776 Bacterial nucleoid DNA-binding protein
YP_001910006.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_001910008.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
YP_001910009.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_001910010.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001910011.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_001910012.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_001910014.1	COG0724 RNA-binding proteins (RRM domain)
YP_001910015.1	COG3306 Glycosyltransferase involved in LPS biosynthesis
YP_001910016.1	COG0492 Thioredoxin reductase
YP_001910017.1	COG0526 Thiol-disulfide isomerase and thioredoxins
YP_001910018.1	COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase
YP_001910019.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_001910020.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_001910023.1	COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
YP_001910024.1	COG1174 ABC-type proline/glycine betaine transport systems, permease component
YP_001910026.1	with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_001910027.1	With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_001910028.1	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
YP_001910029.1	COG0491 Zn-dependent hydrolases, including glyoxylases
YP_001910030.1	COG1565 Uncharacterized conserved protein
YP_001910033.1	COG0742 N6-adenine-specific methylase
YP_001910034.1	interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring
YP_001910035.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_001910037.1	COG1451 Predicted metal-dependent hydrolase
YP_001910038.1	COG3306 Glycosyltransferase involved in LPS biosynthesis
YP_001910039.1	bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate
YP_001910041.1	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
YP_001910042.1	COG1977 Molybdopterin converting factor, small subunit
YP_001910043.1	COG0314 Molybdopterin converting factor, large subunit
YP_001910044.1	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis
YP_001910045.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
YP_001910048.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_001910049.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_001910050.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_001910051.1	COG0606 Predicted ATPase with chaperone activity
YP_001910052.1	COG2217 Cation transport ATPase
YP_001910053.1	COG0732 Restriction endonuclease S subunits
YP_001910055.1	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
YP_001910056.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_001910057.1	participates with LolB in the incorporation of lipoprotein into the outer membrane
YP_001910063.1	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
YP_001910064.1	COG1427 Predicted periplasmic solute-binding protein
YP_001910065.1	Catalyzes the phosphorylation of UMP to UDP
YP_001910066.1	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_001910067.1	COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
YP_001910068.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_001910069.1	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
YP_001910070.1	COG0860 N-acetylmuramoyl-L-alanine amidase
YP_001910072.1	MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis
YP_001910073.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
YP_001910077.1	COG1196 Chromosome segregation ATPases
YP_001910079.1	COG0727 Predicted Fe-S-cluster oxidoreductase
YP_001910080.1	COG0552 Signal recognition particle GTPase
YP_001910082.1	COG0212 5-formyltetrahydrofolate cyclo-ligase
YP_001910083.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
YP_001910084.1	COG0534 Na+-driven multidrug efflux pump
YP_001910085.1	COG2056 Predicted permease
YP_001910087.1	COG0388 Predicted amidohydrolase
YP_001910089.1	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
YP_001910091.1	flagellin specific chaperone
YP_001910092.1	involved in flagellin assembly
YP_001910093.1	possibly involved in flagella export
YP_001910094.1	COG0739 Membrane proteins related to metalloendopeptidases
YP_001910095.1	COG2177 Cell division protein
YP_001910096.1	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
YP_001910097.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_001910098.1	COG3979 Uncharacterized protein contain chitin-binding domain type 3
YP_001910099.1	COG0564 Pseudouridylate synthases, 23S RNA-specific
YP_001910100.1	COG0772 Bacterial cell division membrane protein
YP_001910101.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_001910103.1	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
YP_001910104.1	COG0770 UDP-N-acetylmuramyl pentapeptide synthase
YP_001910105.1	COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)
YP_001910106.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_001910107.1	COG1267 Phosphatidylglycerophosphatase A and related proteins
YP_001910108.1	COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
YP_001910109.1	COG2236 Predicted phosphoribosyltransferases
YP_001910110.1	COG0621 2-methylthioadenine synthetase
YP_001910113.1	COG0621 2-methylthioadenine synthetase
YP_001910115.1	COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
YP_001910116.1	COG0042 tRNA-dihydrouridine synthase
YP_001910118.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB
YP_001910119.1	COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
YP_001910124.1	COG1279 Lysine efflux permease
YP_001910125.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_001910126.1	COG0802 Predicted ATPase or kinase
YP_001910127.1	COG1137 ABC-type (unclassified) transport system, ATPase component
YP_001910128.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_001910129.1	COG1012 NAD-dependent aldehyde dehydrogenases
YP_001910130.1	COG1896 Predicted hydrolases of HD superfamily
YP_001910131.1	COG1912 Uncharacterized conserved protein
YP_001910133.1	COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
YP_001910135.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_001910137.1	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
YP_001910139.1	negatively supercoils closed circular double-stranded DNA
YP_001910140.1	COG0818 Diacylglycerol kinase
YP_001910142.1	COG4647 Acetone carboxylase, gamma subunit
YP_001910143.1	COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit
YP_001910144.1	COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
YP_001910145.1	COG3528 Uncharacterized protein conserved in bacteria
YP_001910146.1	COG2031 Short chain fatty acids transporter
YP_001910148.1	COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
YP_001910149.1	COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
YP_001910150.1	COG0183 Acetyl-CoA acetyltransferase
YP_001910151.1	COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
YP_001910153.1	COG0863 DNA modification methylase
YP_001910154.1	COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
YP_001910155.1	COG0370 Fe2+ transport system protein B
YP_001910156.1	COG4772 Outer membrane receptor for Fe3+-dicitrate
YP_001910157.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_001910159.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_001910162.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_001910163.1	COG0673 Predicted dehydrogenases and related proteins
YP_001910164.1	COG0350 Methylated DNA-protein cysteine methyltransferase
YP_001910165.1	COG0582 Integrase
YP_001910167.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_001910170.1	COG4889 Predicted helicase
YP_001910171.1	COG4889 Predicted helicase
YP_001910172.1	COG0247 Fe-S oxidoreductase
YP_001910173.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_001910175.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_001910176.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_001910177.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_001910178.1	COG2956 Predicted N-acetylglucosaminyl transferase
YP_001910179.1	COG0760 Parvulin-like peptidyl-prolyl isomerase
YP_001910180.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001910181.1	COG0612 Predicted Zn-dependent peptidases
YP_001910182.1	COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
YP_001910183.1	COG4775 Outer membrane protein/protective antigen OMA87
YP_001910184.1	COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
YP_001910185.1	COG1528 Ferritin-like protein
YP_001910186.1	COG0560 Phosphoserine phosphatase
YP_001910189.1	COG1573 Uracil-DNA glycosylase
YP_001910190.1	catalyzes the formation of fumarate from aspartate
YP_001910191.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_001910193.1	COG1210 UDP-glucose pyrophosphorylase
YP_001910194.1	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
YP_001910195.1	COG0762 Predicted integral membrane protein
YP_001910196.1	charges one glutamine molecule and pairs it with tRNA(Gln)
YP_001910198.1	COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
YP_001910199.1	COG0603 Predicted PP-loop superfamily ATPase
YP_001910204.1	COG0680 Ni,Fe-hydrogenase maturation factor
YP_001910205.1	COG1969 Ni,Fe-hydrogenase I cytochrome b subunit
YP_001910206.1	COG0374 Ni,Fe-hydrogenase I large subunit
YP_001910207.1	COG1740 Ni,Fe-hydrogenase I small subunit
YP_001910208.1	COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
YP_001910209.1	COG1479 Uncharacterized conserved protein
YP_001910210.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001910211.1	COG2171 Tetrahydrodipicolinate N-succinyltransferase
YP_001910212.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_001910213.1	COG0436 Aspartate/tyrosine/aromatic aminotransferase
YP_001910214.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_001910216.1	MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange
YP_001910217.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_001910218.1	COG0840 Methyl-accepting chemotaxis protein
YP_001910219.1	COG3306 Glycosyltransferase involved in LPS biosynthesis
YP_001910220.1	COG3306 Glycosyltransferase involved in LPS biosynthesis
YP_001910221.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_001910222.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_001910223.1	COG0835 Chemotaxis signal transduction protein
YP_001910224.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_001910225.1	COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
YP_001910226.1	COG1131 ABC-type multidrug transport system, ATPase component
YP_001910227.1	COG0842 ABC-type multidrug transport system, permease component
YP_001910229.1	COG0015 Adenylosuccinate lyase
YP_001910230.1	COG0841 Cation/multidrug efflux pump
YP_001910231.1	COG0845 Membrane-fusion protein
YP_001910232.1	COG1538 Outer membrane protein
YP_001910233.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_001910235.1	COG2231 Uncharacterized protein related to Endonuclease III
YP_001910236.1	FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions
YP_001910237.1	COG1132 ABC-type multidrug transport system, ATPase and permease components
YP_001910238.1	COG1132 ABC-type multidrug transport system, ATPase and permease components
YP_001910239.1	COG0840 Methyl-accepting chemotaxis protein
YP_001910240.1	COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
YP_001910241.1	COG0744 Membrane carboxypeptidase (penicillin-binding protein)
YP_001910242.1	Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells
YP_001910244.1	COG1495 Disulfide bond formation protein DsbB
YP_001910246.1	COG5610 Predicted hydrolase (HAD superfamily)
YP_001910247.1	COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
YP_001910248.1	COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
YP_001910249.1	COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
YP_001910250.1	COG1146 Ferredoxin
YP_001910252.1	COG1559 Predicted periplasmic solute-binding protein
YP_001910254.1	COG1918 Fe2+ transport system protein A
YP_001910255.1	COG0177 Predicted EndoIII-related endonuclease
YP_001910256.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_001910258.1	COG0810 Periplasmic protein TonB, links inner and outer membranes
YP_001910259.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_001910260.1	COG4692 Predicted neuraminidase (sialidase)
YP_001910262.1	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
YP_001910263.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_001910264.1	COG0681 Signal peptidase I
YP_001910265.1	COG1994 Zn-dependent proteases
YP_001910266.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_001910268.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_001910269.1	COG0586 Uncharacterized membrane-associated protein
YP_001910270.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_001910271.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_001910272.1	COG0535 Predicted Fe-S oxidoreductases
YP_001910273.1	COG0628 Predicted permease
YP_001910274.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_001910275.1	COG3059 Predicted membrane protein
YP_001910278.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_001910279.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_001910280.1	carries the fatty acid chain in fatty acid biosynthesis
YP_001910282.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_001910283.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_001910289.1	COG0566 rRNA methylases
YP_001910290.1	COG0313 Predicted methyltransferases
YP_001910291.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_001910292.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_001910293.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_001910298.1	COG3451 Type IV secretory pathway, VirB4 components
YP_001910302.1	COG0249 Mismatch repair ATPase (MutS family)
YP_001910319.1	COG3736 Type IV secretory pathway, component VirB8
YP_001910321.1	COG3504 Type IV secretory pathway, VirB9 components
YP_001910322.1	COG2948 Type IV secretory pathway, VirB10 components
YP_001910325.1	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
YP_001910326.1	COG3505 Type IV secretory pathway, VirD4 components
YP_001910331.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001910332.1	COG3034 Uncharacterized protein conserved in bacteria
YP_001910333.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_001910334.1	heat shock protein involved in degradation of misfolded proteins
YP_001910335.1	heat shock protein involved in degradation of misfolded proteins
YP_001910336.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_001910337.1	COG1479 Uncharacterized conserved protein
YP_001910338.1	COG0174 Glutamine synthetase
YP_001910340.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_001910341.1	COG0277 FAD/FMN-containing dehydrogenases
YP_001910343.1	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
YP_001910344.1	COG0739 Membrane proteins related to metalloendopeptidases
YP_001910347.1	negatively supercoils closed circular double-stranded DNA
YP_001910348.1	binds the polymerase to DNA and acts as a sliding clamp
YP_001910349.1	COG2829 Outer membrane phospholipase A
YP_001910350.1	COG0733 Na+-dependent transporters of the SNF family
YP_001910351.1	COG0733 Na+-dependent transporters of the SNF family
YP_001910352.1	COG0824 Predicted thioesterase
YP_001910354.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_001910355.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_001910357.1	required for 70S ribosome assembly
YP_001910358.1	COG1226 Kef-type K+ transport systems, predicted NAD-binding component
YP_001910359.1	COG0467 RecA-superfamily ATPases implicated in signal transduction
YP_001910361.1	COG0582 Integrase
YP_001910367.1	COG0827 Adenine-specific DNA methylase
YP_001910368.1	COG1192 ATPases involved in chromosome partitioning
YP_001910371.1	COG3843 Type IV secretory pathway, VirD2 components (relaxase)
YP_001910373.1	COG3041 Uncharacterized protein conserved in bacteria
YP_001910374.1	COG3505 Type IV secretory pathway, VirD4 components
YP_001910378.1	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
YP_001910383.1	COG2948 Type IV secretory pathway, VirB10 components
YP_001910384.1	COG3504 Type IV secretory pathway, VirB9 components
YP_001910385.1	COG3736 Type IV secretory pathway, component VirB8
YP_001910387.1	COG0550 Topoisomerase IA
YP_001910388.1	COG3451 Type IV secretory pathway, VirB4 components
YP_001910396.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_001910398.1	COG0728 Uncharacterized membrane protein, putative virulence factor
YP_001910399.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_001910402.1	COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
YP_001910403.1	COG0609 ABC-type Fe3+-siderophore transport system, permease component
YP_001910404.1	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
YP_001910405.1	COG1607 Acyl-CoA hydrolase
YP_001910406.1	COG3041 Uncharacterized protein conserved in bacteria
YP_001910411.1	COG0409 Hydrogenase maturation factor
YP_001910412.1	COG0298 Hydrogenase maturation factor
YP_001910413.1	COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
YP_001910415.1	COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
YP_001910416.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_001910417.1	COG0280 Phosphotransacetylase
YP_001910419.1	acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod
YP_001910420.1	the hook connects flagellar basal body to the flagellar filament
YP_001910422.1	COG0827 Adenine-specific DNA methylase
YP_001910423.1	COG0210 Superfamily I DNA and RNA helicases
YP_001910428.1	COG1629 Outer membrane receptor proteins, mostly Fe transport
YP_001910430.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_001910431.1	COG0670 Integral membrane protein, interacts with FtsH
YP_001910432.1	COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
YP_001910434.1	COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
YP_001910435.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_001910436.1	catalyzes the modification of U13 in tRNA(Glu)
YP_001910437.1	putative metalloprotease
YP_001910438.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_001910439.1	COG0142 Geranylgeranyl pyrophosphate synthase
YP_001910440.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_001910442.1	COG0720 6-pyruvoyl-tetrahydropterin synthase
YP_001910443.1	COG0602 Organic radical activating enzymes
YP_001910444.1	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
YP_001910446.1	COG0477 Permeases of the major facilitator superfamily
YP_001910447.1	COG1479 Uncharacterized conserved protein
YP_001910448.1	COG0765 ABC-type amino acid transport system, permease component
YP_001910449.1	COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
YP_001910451.1	COG0787 Alanine racemase
YP_001910452.1	COG1115 Na+/alanine symporter
YP_001910453.1	COG0665 Glycine/D-amino acid oxidases (deaminating)
YP_001910454.1	COG0251 Putative translation initiation inhibitor, yjgF family
YP_001910458.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_001910459.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
YP_001910460.1	COG0540 Aspartate carbamoyltransferase, catalytic chain
YP_001910461.1	COG1546 Uncharacterized protein (competence- and mitomycin-induced)
YP_001910463.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_001910464.1	COG0564 Pseudouridylate synthases, 23S RNA-specific
YP_001910465.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
YP_001910466.1	COG1579 Zn-ribbon protein, possibly nucleic acid-binding
YP_001910467.1	COG0327 Uncharacterized conserved protein
YP_001910468.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001910469.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_001910471.1	COG0699 Predicted GTPases (dynamin-related)
YP_001910473.1	COG3309 Uncharacterized virulence-associated protein D
YP_001910475.1	COG3696 Putative silver efflux pump
YP_001910476.1	COG0845 Membrane-fusion protein
YP_001910478.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001910480.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_001910481.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_001910482.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
YP_001910483.1	COG0760 Parvulin-like peptidyl-prolyl isomerase
YP_001910484.1	COG0849 Actin-like ATPase involved in cell division
YP_001910485.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_001910487.1	COG0668 Small-conductance mechanosensitive channel
YP_001910489.1	COG1570 Exonuclease VII, large subunit
YP_001910494.1	COG0343 Queuine/archaeosine tRNA-ribosyltransferase
YP_001910497.1	COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain
YP_001910499.1	COG1479 Uncharacterized conserved protein
YP_001910502.1	catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis
YP_001910503.1	COG0438 Glycosyltransferase
YP_001910504.1	COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
YP_001910505.1	COG0500 SAM-dependent methyltransferases
YP_001910507.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_001910508.1	COG2230 Cyclopropane fatty acid synthase and related methyltransferases
YP_001910509.1	COG0668 Small-conductance mechanosensitive channel
YP_001910513.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_001910515.1	COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
YP_001910517.1	COG0520 Selenocysteine lyase
YP_001910518.1	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
YP_001910519.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_001910520.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_001910521.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_001910522.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_001910523.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_001910525.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_001910526.1	COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
YP_001910527.1	COG0325 Predicted enzyme with a TIM-barrel fold
YP_001910528.1	COG2908 Uncharacterized protein conserved in bacteria
YP_001910529.1	COG0835 Chemotaxis signal transduction protein
YP_001910530.1	COG0643 Chemotaxis protein histidine kinase and related kinases
YP_001910531.1	COG0835 Chemotaxis signal transduction protein
YP_001910532.1	COG2077 Peroxiredoxin
YP_001910533.1	COG0605 Superoxide dismutase
YP_001910534.1	COG0500 SAM-dependent methyltransferases
YP_001910535.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_001910537.1	COG0055 F0F1-type ATP synthase, beta subunit
YP_001910541.1	COG2890 Methylase of polypeptide chain release factors
YP_001910542.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_001910544.1	COG1333 ResB protein required for cytochrome c biosynthesis
YP_001910545.1	COG2143 Thioredoxin-related protein
YP_001910546.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_001910548.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_001910550.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_001910551.1	COG0511 Biotin carboxyl carrier protein
YP_001910552.1	biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_001910556.1	COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
YP_001910557.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
YP_001910558.1	catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins
YP_001910559.1	COG0795 Predicted permeases
YP_001910560.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_001910561.1	COG1087 UDP-glucose 4-epimerase
YP_001910563.1	COG4221 Short-chain alcohol dehydrogenase of unknown specificity
YP_001910564.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001910565.1	COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
YP_001910566.1	catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate
YP_001910567.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_001910568.1	COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
YP_001910569.1	catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate
YP_001910570.1	COG1064 Zn-dependent alcohol dehydrogenases
YP_001910571.1	COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
YP_001910572.1	COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
YP_001910575.1	COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
YP_001910576.1	COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit
YP_001910577.1	COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
YP_001910578.1	COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
YP_001910579.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_001910581.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_001910585.1	COG0790 FOG: TPR repeat, SEL1 subfamily
YP_001910587.1	COG0405 Gamma-glutamyltransferase
YP_001910588.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
YP_001910590.1	COG0270 Site-specific DNA methylase
YP_001910594.1	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
YP_001910596.1	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins
YP_001910597.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_001910599.1	COG0848 Biopolymer transport protein
YP_001910600.1	COG0811 Biopolymer transport proteins
YP_001910601.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_001910602.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_001910603.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_001910604.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_001910605.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_001910606.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_001910607.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.
YP_001910608.1	COG1475 Predicted transcriptional regulators
YP_001910609.1	COG1192 ATPases involved in chromosome partitioning
YP_001910610.1	catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon
YP_001910611.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_001910612.1	COG4487 Uncharacterized protein conserved in bacteria
YP_001910616.1	COG1432 Uncharacterized conserved protein
YP_001910618.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_001910619.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_001910620.1	Essential for efficient processing of 16S rRNA
YP_001910621.1	COG1837 Predicted RNA-binding protein (contains KH domain)
YP_001910622.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_001910623.1	COG0541 Signal recognition particle GTPase
YP_001910624.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_001910625.1	binds to flagellin and appears to stabilize flagellin during flagella assembly
YP_001910626.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_001910629.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_001910630.1	COG2184 Protein involved in cell division
YP_001910631.1	COG0319 Predicted metal-dependent hydrolase
YP_001910632.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_001910633.1	COG0586 Uncharacterized membrane-associated protein
YP_001910634.1	COG3197 Uncharacterized protein, possibly involved in nitrogen fixation
YP_001910635.1	COG0492 Thioredoxin reductase
YP_001910636.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_001910640.1	COG1966 Carbon starvation protein, predicted membrane protein
YP_001910641.1	COG0765 ABC-type amino acid transport system, permease component
YP_001910642.1	COG0765 ABC-type amino acid transport system, permease component
YP_001910643.1	COG1126 ABC-type polar amino acid transport system, ATPase component
YP_001910644.1	COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
YP_001910647.1	COG0738 Fucose permease
YP_001910648.1	COG2252 Permeases
YP_001910653.1	COG0813 Purine-nucleoside phosphorylase
YP_001910654.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_001910655.1	COG1972 Nucleoside permease
YP_001910656.1	COG0477 Permeases of the major facilitator superfamily
YP_001910657.1	COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
YP_001910658.1	COG0475 Kef-type K+ transport systems, membrane components
YP_001910659.1	COG0534 Na+-driven multidrug efflux pump
YP_001910660.1	COG2814 Arabinose efflux permease
YP_001910661.1	COG3338 Carbonic anhydrase
YP_001910663.1	COG0136 Aspartate-semialdehyde dehydrogenase
YP_001910664.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_001910665.1	COG0859 ADP-heptose:LPS heptosyltransferase
YP_001910668.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_001910669.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_001910670.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_001910671.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_001910673.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_001910674.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_001910675.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_001910676.1	binds directly to 23S ribosomal RNA
YP_001910677.1	Modulates Rho-dependent transcription termination
YP_001910678.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_001910679.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_001910680.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001910681.1	COG1132 ABC-type multidrug transport system, ATPase and permease components
YP_001910682.1	COG0546 Predicted phosphatases
YP_001910683.1	COG3392 Adenine-specific DNA methylase
YP_001910685.1	COG1045 Serine acetyltransferase
YP_001910687.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_001910688.1	COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
YP_001910689.1	COG1926 Predicted phosphoribosyltransferases
YP_001910690.1	COG1452 Organic solvent tolerance protein OstA
YP_001910692.1	COG0151 Phosphoribosylamine-glycine ligase
YP_001910694.1	COG1131 ABC-type multidrug transport system, ATPase component
YP_001910695.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
YP_001910696.1	COG0277 FAD/FMN-containing dehydrogenases
YP_001910697.1	COG0607 Rhodanese-related sulfurtransferase
YP_001910698.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis
YP_001910699.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_001910700.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_001910701.1	COG2863 Cytochrome c553
YP_001910702.1	hydrolyzes diadenosine polyphosphate
YP_001910703.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_001910705.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_001910706.1	COG0294 Dihydropteroate synthase and related enzymes
YP_001910708.1	COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
YP_001910711.1	COG2952 Uncharacterized protein conserved in bacteria
YP_001910712.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_001910713.1	formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate
YP_001910715.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_001910716.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001910717.1	COG2841 Uncharacterized protein conserved in bacteria
YP_001910721.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_001910722.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_001910723.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_001910724.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_001910725.1	COG0557 Exoribonuclease R
YP_001910726.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_001910728.1	COG4166 ABC-type oligopeptide transport system, periplasmic component
YP_001910729.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001910730.1	COG0500 SAM-dependent methyltransferases
YP_001910731.1	COG1314 Preprotein translocase subunit SecG
YP_001910732.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_001910733.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001910734.1	COG1714 Predicted membrane protein/domain
YP_001910735.1	COG0846 NAD-dependent protein deacetylases, SIR2 family
YP_001910736.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_001910737.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_001910738.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_001910739.1	Catalyzes the transfer of electrons from NADH to quinone
YP_001910742.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_001910743.1	Catalyzes the transfer of electrons from NADH to quinone
YP_001910744.1	Catalyzes the transfer of electrons from NADH to quinone
YP_001910745.1	Catalyzes the transfer of electrons from NADH to quinone
YP_001910746.1	Catalyzes the transfer of electrons from NADH to quinone
YP_001910747.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_001910748.1	Catalyzes the transfer of electrons from NADH to quinone
YP_001910749.1	Catalyzes the transfer of electrons from NADH to quinone
YP_001910750.1	COG1729 Uncharacterized protein conserved in bacteria
YP_001910751.1	COG1109 Phosphomannomutase
YP_001910753.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_001910754.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_001910755.1	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate
YP_001910756.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001910757.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
YP_001910758.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_001910759.1	COG0859 ADP-heptose:LPS heptosyltransferase
YP_001910760.1	COG2503 Predicted secreted acid phosphatase
YP_001910761.1	COG2353 Uncharacterized conserved protein
YP_001910763.1	COG0819 Putative transcription activator
YP_001910764.1	COG3201 Nicotinamide mononucleotide transporter
YP_001910765.1	COG1564 Thiamine pyrophosphokinase
YP_001910767.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_001910768.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_001910769.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_001910770.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_001910771.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_001910772.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_001910773.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_001910774.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_001910775.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_001910776.1	late assembly protein
YP_001910777.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_001910778.1	binds 5S rRNA along with protein L5 and L25
YP_001910779.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_001910780.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_001910781.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
YP_001910782.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_001910783.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_001910784.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_001910785.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_001910786.1	one of the stabilizing components for the large ribosomal subunit
YP_001910787.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_001910788.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_001910789.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_001910790.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_001910791.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_001910792.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_001910793.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_001910794.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_001910795.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_001910796.1	COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
YP_001910798.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_001910800.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_001910803.1	COG0845 Membrane-fusion protein
YP_001910804.1	COG3696 Putative silver efflux pump
YP_001910805.1	COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance)
YP_001910806.1	COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
YP_001910807.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_001910810.1	COG1432 Uncharacterized conserved protein
YP_001910811.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_001910812.1	COG2214 DnaJ-class molecular chaperone
YP_001910813.1	COG1057 Nicotinic acid mononucleotide adenylyltransferase
YP_001910814.1	Inhibits transcription at high concentrations of nickel
YP_001910815.1	COG0811 Biopolymer transport proteins
YP_001910816.1	COG0848 Biopolymer transport protein
YP_001910817.1	COG0810 Periplasmic protein TonB, links inner and outer membranes
YP_001910818.1	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
YP_001910819.1	COG0598 Mg2+ and Co2+ transporters
YP_001910820.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_001910821.1	COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
YP_001910822.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_001910823.1	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
YP_001910825.1	COG0793 Periplasmic protease
YP_001910828.1	COG0863 DNA modification methylase
YP_001910830.1	COG4889 Predicted helicase
YP_001910831.1	catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
YP_001910832.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_001910833.1	catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_001910836.1	UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin
YP_001910837.1	COG0658 Predicted membrane metal-binding protein
YP_001910838.1	unwinds double stranded DNA
YP_001910839.1	COG0062 Uncharacterized conserved protein
YP_001910840.1	COG0642 Signal transduction histidine kinase
YP_001910841.1	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001910844.1	COG0338 Site-specific DNA methylase
YP_001910845.1	COG2189 Adenine specific DNA methylase Mod
YP_001910846.1	COG2189 Adenine specific DNA methylase Mod
YP_001910847.1	COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
YP_001910848.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_001910849.1	functions in MreBCD complex in some organisms
YP_001910850.1	binds and unfolds substrates as part of the ClpXP protease
YP_001910851.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
YP_001910852.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_001910853.1	binds to flagellin and appears to stabilize flagellin during flagella assembly
YP_001910855.1	COG4105 DNA uptake lipoprotein
YP_001910856.1	COG0466 ATP-dependent Lon protease, bacterial type
YP_001910857.1	catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate
YP_001910858.1	COG1864 DNA/RNA endonuclease G, NUC1
YP_001910859.1	COG2189 Adenine specific DNA methylase Mod
YP_001910860.1	catalyzes the formation of biotin from dethiobiotin and sulfur
YP_001910861.1	COG1295 Predicted membrane protein
YP_001910866.1	NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis
YP_001910867.1	COG0799 Uncharacterized homolog of plant Iojap protein
YP_001910868.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_001910869.1	COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
YP_001910870.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_001910871.1	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus
YP_001910872.1	involved in type III protein export during flagellum assembly
YP_001910873.1	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
YP_001910874.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_001910875.1	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
YP_001910878.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_001910879.1	COG0794 Predicted sugar phosphate isomerase involved in capsule formation
YP_001910880.1	COG1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain
YP_001910881.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_001910883.1	COG0732 Restriction endonuclease S subunits
YP_001910884.1	COG0788 Formyltetrahydrofolate hydrolase
YP_001910885.1	COG0616 Periplasmic serine proteases (ClpP class)
YP_001910888.1	COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
YP_001910893.1	COG3676 Transposase and inactivated derivatives
YP_001910898.1	COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
YP_001910899.1	affects carbohydrate metabolism, has regulatory role in many processes
YP_001910900.1	catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis
YP_001910901.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_001910902.1	COG0811 Biopolymer transport proteins
YP_001910903.1	COG0848 Biopolymer transport protein
YP_001910904.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_001910905.1	COG0594 RNase P protein component
YP_001910906.1	COG0759 Uncharacterized conserved protein
YP_001910907.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_001910908.1	COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain
YP_001910909.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_001910913.1	COG0481 Membrane GTPase LepA
YP_001910916.1	COG0526 Thiol-disulfide isomerase and thioredoxins
YP_001910917.1	COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
YP_001910918.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
YP_001910919.1	COG1858 Cytochrome c peroxidase
YP_001910921.1	COG3187 Heat shock protein
YP_001910923.1	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
YP_001910924.1	COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
YP_001910925.1	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
YP_001910927.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_001910929.1	COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
YP_001910931.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_001910932.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_001910933.1	catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate
YP_001910935.1	required for the assembly of the flagellar basal body P-ring
YP_001910936.1	COG0210 Superfamily I DNA and RNA helicases
YP_001910937.1	COG0457 FOG: TPR repeat
YP_001910938.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001910939.1	COG0388 Predicted amidohydrolase
YP_001910940.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
YP_001910941.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
YP_001910942.1	COG1981 Predicted membrane protein
YP_001910943.1	COG1739 Uncharacterized conserved protein
YP_001910944.1	COG0842 ABC-type multidrug transport system, permease component
YP_001910945.1	COG0842 ABC-type multidrug transport system, permease component
YP_001910946.1	COG0845 Membrane-fusion protein
YP_001910947.1	COG1538 Outer membrane protein
YP_001910948.1	COG1253 Hemolysins and related proteins containing CBS domains
YP_001910949.1	COG0306 Phosphate/sulphate permeases
YP_001910950.1	COG0694 Thioredoxin-like proteins and domains
YP_001910952.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_001910953.1	Important for the balance of metabolites in the pentose-phosphate pathway
YP_001910954.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_001910955.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_001910956.1	COG0795 Predicted permeases
YP_001910957.1	COG0209 Ribonucleotide reductase, alpha subunit
YP_001910959.1	COG3399 Uncharacterized protein conserved in bacteria
YP_001910960.1	COG2217 Cation transport ATPase
YP_001910961.1	COG4123 Predicted O-methyltransferase
YP_001910962.1	COG0117 Pyrimidine deaminase
YP_001910963.1	COG0786 Na+/glutamate symporter
YP_001910964.1	COG1748 Saccharopine dehydrogenase and related proteins
YP_001910965.1	COG0348 Polyferredoxin
YP_001910966.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
YP_001910967.1	COG1539 Dihydroneopterin aldolase
YP_001910969.1	catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis
YP_001910970.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_001910973.1	COG3600 Uncharacterized phage-associated protein
YP_001910974.1	COG3344 Retron-type reverse transcriptase
YP_001910976.1	COG1002 Type II restriction enzyme, methylase subunits
YP_001910977.1	COG3587 Restriction endonuclease
YP_001910978.1	COG2189 Adenine specific DNA methylase Mod
YP_001910979.1	catalyzes branch migration in Holliday junction intermediates
YP_001910982.1	AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.
YP_001910986.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_001910987.1	COG0813 Purine-nucleoside phosphorylase
YP_001910989.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_001910990.1	flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor
YP_001910992.1	COG0732 Restriction endonuclease S subunits
YP_001910993.1	COG0286 Type I restriction-modification system methyltransferase subunit
YP_001910994.1	COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
YP_001910995.1	COG1451 Predicted metal-dependent hydrolase
YP_001910996.1	COG1629 Outer membrane receptor proteins, mostly Fe transport
YP_001910998.1	COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
YP_001910999.1	COG0686 Alanine dehydrogenase
YP_001911000.1	COG1479 Uncharacterized conserved protein
YP_001911002.1	COG0061 Predicted sugar kinase
YP_001911003.1	COG0497 ATPase involved in DNA repair
YP_001911004.1	COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP
YP_001911009.1	3'-5' exonuclease of DNA polymerase III
YP_001911010.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_001911011.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
YP_001911013.1	COG0827 Adenine-specific DNA methylase
YP_001911016.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_001911017.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_001911019.1	COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
YP_001911020.1	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH
YP_001911021.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
YP_001911022.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_001911023.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_001911025.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_001911027.1	COG0285 Folylpolyglutamate synthase
YP_001911028.1	COG0739 Membrane proteins related to metalloendopeptidases
YP_001911029.1	COG1664 Integral membrane protein CcmA involved in cell shape determination
YP_001911030.1	COG1197 Transcription-repair coupling factor (superfamily II helicase)
YP_001911031.1	COG0723 Rieske Fe-S protein
YP_001911032.1	COG1290 Cytochrome b subunit of the bc complex
YP_001911033.1	COG2857 Cytochrome c1
YP_001911035.1	COG0768 Cell division protein FtsI/penicillin-binding protein 2
YP_001911036.1	forms a junction between the M-ring and FlgB during flagella biosynthesis
YP_001911037.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
YP_001911038.1	with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella
YP_001911039.1	COG0772 Bacterial cell division membrane protein
YP_001911040.1	COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
YP_001911041.1	COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
YP_001911042.1	COG0450 Peroxiredoxin
YP_001911043.1	COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
YP_001911044.1	COG0768 Cell division protein FtsI/penicillin-binding protein 2
YP_001911046.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_001911047.1	COG1934 Uncharacterized protein conserved in bacteria
YP_001911049.1	COG1778 Low specificity phosphatase (HAD superfamily)
YP_001911050.1	COG0797 Lipoproteins
YP_001911051.1	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
YP_001911052.1	COG0084 Mg-dependent DNase
YP_001911053.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_001911054.1	COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB
YP_001911055.1	part of the metNIQ transport system for methionine
YP_001911056.1	COG2011 ABC-type metal ion transport system, permease component
YP_001911058.1	COG0671 Membrane-associated phospholipid phosphatase
YP_001911059.1	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
YP_001911060.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
YP_001911061.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
YP_001911062.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_001911063.1	makes up the distal portion of the flagellar basal body rod
YP_001911066.1	COG4735 Uncharacterized protein conserved in bacteria