-- dump date 20140619_114207 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001909500.1 188526813 6296652 complement(11..427) 1 NC_010698.2 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 427 nusB 6296652 nusB Helicobacter pylori Shi470 transcription antitermination protein NusB YP_001909500.1 11 R 512562 CDS YP_001909501.1 188526814 6296946 complement(429..899) 1 NC_010698.2 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 899 ribH 6296946 ribH Helicobacter pylori Shi470 6,7-dimethyl-8-ribityllumazine synthase YP_001909501.1 429 R 512562 CDS YP_001909502.1 188526815 6297023 complement(909..1739) 1 NC_010698.2 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1739 6297023 HPSH_00015 Helicobacter pylori Shi470 2-dehydro-3-deoxyphosphooctonate aldolase YP_001909502.1 909 R 512562 CDS YP_001909503.1 188526816 6296028 complement(1726..2391) 1 NC_010698.2 COG0288 Carbonic anhydrase; beta-carbonic anhydrase 2391 6296028 HPSH_00020 Helicobacter pylori Shi470 beta-carbonic anhydrase YP_001909503.1 1726 R 512562 CDS YP_001909504.1 188526817 6296030 2514..3197 1 NC_010698.2 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 3197 6296030 HPSH_00025 Helicobacter pylori Shi470 orotidine 5'-phosphate decarboxylase YP_001909504.1 2514 D 512562 CDS YP_001909505.1 188526818 6296088 3198..4028 1 NC_010698.2 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 4028 panC 6296088 panC Helicobacter pylori Shi470 pantoate--beta-alanine ligase YP_001909505.1 3198 D 512562 CDS YP_001909506.1 188526819 6296175 complement(7229..7312) 1 NC_010698.2 hypothetical protein 7312 6296175 HPSH_00045 Helicobacter pylori Shi470 hypothetical protein YP_001909506.1 7229 R 512562 CDS YP_001909507.1 188526820 6296621 complement(7356..8996) 1 NC_010698.2 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 8996 groEL 6296621 groEL Helicobacter pylori Shi470 chaperonin GroEL YP_001909507.1 7356 R 512562 CDS YP_001909508.1 188526821 6295998 complement(9021..9377) 1 NC_010698.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 9377 groES 6295998 groES Helicobacter pylori Shi470 co-chaperonin GroES YP_001909508.1 9021 R 512562 CDS YP_001909509.1 188526822 6296995 9663..11342 1 NC_010698.2 synthesizes RNA primers at the replication forks; DNA primase 11342 dnaG 6296995 dnaG Helicobacter pylori Shi470 DNA primase YP_001909509.1 9663 D 512562 CDS YP_001909510.1 188526823 6296475 11339..12391 1 NC_010698.2 COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; argininosuccinate synthase 12391 6296475 HPSH_00065 Helicobacter pylori Shi470 argininosuccinate synthase YP_001909510.1 11339 D 512562 CDS YP_001909511.1 188526824 6296218 12388..12498 1 NC_010698.2 hypothetical protein 12498 6296218 HPSH_00070 Helicobacter pylori Shi470 hypothetical protein YP_001909511.1 12388 D 512562 CDS YP_001909512.1 188526825 6296376 12483..13310 1 NC_010698.2 hypothetical protein 13310 6296376 HPSH_00075 Helicobacter pylori Shi470 hypothetical protein YP_001909512.1 12483 D 512562 CDS YP_001909513.1 188526826 6297215 13456..13737 1 NC_010698.2 hypothetical protein 13737 6297215 HPSH_00080 Helicobacter pylori Shi470 hypothetical protein YP_001909513.1 13456 D 512562 CDS YP_001909514.1 188526827 6296405 13737..14000 1 NC_010698.2 hypothetical protein 14000 6296405 HPSH_00085 Helicobacter pylori Shi470 hypothetical protein YP_001909514.1 13737 D 512562 CDS YP_001909515.1 188526828 6297112 14002..16365 1 NC_010698.2 COG3451 Type IV secretory pathway, VirB4 components; hypothetical protein 16365 6297112 HPSH_00090 Helicobacter pylori Shi470 hypothetical protein YP_001909515.1 14002 D 512562 CDS YP_001909516.1 188526829 6297013 16686..18026 1 NC_010698.2 COG3014 Uncharacterized protein conserved in bacteria; hypothetical protein 18026 6297013 HPSH_00095 Helicobacter pylori Shi470 hypothetical protein YP_001909516.1 16686 D 512562 CDS YP_001909517.1 188526830 6296390 18121..19086 1 NC_010698.2 COG0835 Chemotaxis signal transduction protein; chemotaxis protein CheV 19086 6296390 HPSH_00100 Helicobacter pylori Shi470 chemotaxis protein CheV YP_001909517.1 18121 D 512562 CDS YP_001909518.1 188526831 6296449 19083..20300 1 NC_010698.2 COG0019 Diaminopimelate decarboxylase; carboxynorspermidine decarboxylase 20300 6296449 HPSH_00105 Helicobacter pylori Shi470 carboxynorspermidine decarboxylase YP_001909518.1 19083 D 512562 CDS YP_001909519.1 188526832 6296443 complement(20310..20882) 1 NC_010698.2 inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase 20882 6296443 HPSH_00110 Helicobacter pylori Shi470 lipid A 1-phosphatase YP_001909519.1 20310 R 512562 CDS YP_001909520.1 188526833 6296976 complement(20893..22464) 1 NC_010698.2 attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase 22464 6296976 HPSH_00115 Helicobacter pylori Shi470 lipid A phosphoethanolamine transferase YP_001909520.1 20893 R 512562 CDS YP_001909521.1 188526834 6296513 complement(22801..24867) 1 NC_010698.2 outer membrane protein HopD 24867 6296513 HPSH_00120 Helicobacter pylori Shi470 outer membrane protein HopD YP_001909521.1 22801 R 512562 CDS YP_001909522.1 188526835 6296072 25187..25312 1 NC_010698.2 hypothetical protein 25312 6296072 HPSH_00125 Helicobacter pylori Shi470 hypothetical protein YP_001909522.1 25187 D 512562 CDS YP_001909523.1 188526836 6296862 complement(25379..26659) 1 NC_010698.2 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 26659 gltA 6296862 gltA Helicobacter pylori Shi470 type II citrate synthase YP_001909523.1 25379 R 512562 CDS YP_001909524.1 188526837 6297285 26857..28134 1 NC_010698.2 COG0538 Isocitrate dehydrogenases; isocitrate dehydrogenase (icd) 28134 6297285 HPSH_00135 Helicobacter pylori Shi470 isocitrate dehydrogenase (icd) YP_001909524.1 26857 D 512562 CDS YP_001909525.1 188526838 6297171 28206..28733 1 NC_010698.2 hypothetical protein 28733 6297171 HPSH_00140 Helicobacter pylori Shi470 hypothetical protein YP_001909525.1 28206 D 512562 CDS YP_001909526.1 188526839 6296206 complement(28710..29366) 1 NC_010698.2 COG0132 Dethiobiotin synthetase; dethiobiotin synthetase 29366 6296206 HPSH_00145 Helicobacter pylori Shi470 dethiobiotin synthetase YP_001909526.1 28710 R 512562 CDS YP_001909527.1 188526840 6296105 complement(29370..29690) 1 NC_010698.2 hypothetical protein 29690 6296105 HPSH_00150 Helicobacter pylori Shi470 hypothetical protein YP_001909527.1 29370 R 512562 CDS YP_001909528.1 188526841 6296297 29869..30282 1 NC_010698.2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; hypothetical protein 30282 6296297 HPSH_00155 Helicobacter pylori Shi470 hypothetical protein YP_001909528.1 29869 D 512562 CDS YP_001909529.1 188526842 6297404 30290..30565 1 NC_010698.2 COG2127 Uncharacterized conserved protein; hypothetical protein 30565 6297404 HPSH_00160 Helicobacter pylori Shi470 hypothetical protein YP_001909529.1 30290 D 512562 CDS YP_001909530.1 188526843 6296191 30565..32787 1 NC_010698.2 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent C1p protease ClpA 32787 6296191 HPSH_00165 Helicobacter pylori Shi470 ATP-dependent C1p protease ClpA YP_001909530.1 30565 D 512562 CDS YP_001909531.1 188526844 6296259 32777..33127 1 NC_010698.2 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 33127 6296259 HPSH_00170 Helicobacter pylori Shi470 aspartate alpha-decarboxylase YP_001909531.1 32777 D 512562 CDS YP_001909532.1 188526845 6296722 33138..33440 1 NC_010698.2 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 33440 6296722 HPSH_00175 Helicobacter pylori Shi470 hypothetical protein YP_001909532.1 33138 D 512562 CDS YP_001909533.1 188526846 6297393 33440..34435 1 NC_010698.2 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; hypothetical protein 34435 6297393 HPSH_00180 Helicobacter pylori Shi470 hypothetical protein YP_001909533.1 33440 D 512562 CDS YP_001909534.1 188526847 6296604 34441..35496 1 NC_010698.2 NADH-ubiquinone oxidoreductase subunit 35496 6296604 HPSH_00185 Helicobacter pylori Shi470 NADH-ubiquinone oxidoreductase subunit YP_001909534.1 34441 D 512562 CDS YP_001909535.1 188526848 6296602 35512..35625 1 NC_010698.2 comB7 putative lipoprotein 35625 6296602 HPSH_00190 Helicobacter pylori Shi470 comB7 putative lipoprotein YP_001909535.1 35512 D 512562 CDS YP_001909536.1 188526849 6296171 35622..36365 1 NC_010698.2 COG3736 Type IV secretory pathway, component VirB8; comB8 competence protein 36365 6296171 HPSH_00195 Helicobacter pylori Shi470 comB8 competence protein YP_001909536.1 35622 D 512562 CDS YP_001909537.1 188526850 6296613 36365..37330 1 NC_010698.2 COG3504 Type IV secretory pathway, VirB9 components; comB9 competence protein 37330 6296613 HPSH_00200 Helicobacter pylori Shi470 comB9 competence protein YP_001909537.1 36365 D 512562 CDS YP_001909538.1 188526851 6297487 37323..38459 1 NC_010698.2 COG2948 Type IV secretory pathway, VirB10 components; comB10 competence protein 38459 6297487 HPSH_00205 Helicobacter pylori Shi470 comB10 competence protein YP_001909538.1 37323 D 512562 CDS YP_001909539.1 188526852 6296748 38530..39942 1 NC_010698.2 COG0836 Mannose-1-phosphate guanylyltransferase; mannose-6-phosphate isomerase 39942 6296748 HPSH_00210 Helicobacter pylori Shi470 mannose-6-phosphate isomerase YP_001909539.1 38530 D 512562 CDS YP_001909540.1 188526853 6296102 39970..41115 1 NC_010698.2 COG1089 GDP-D-mannose dehydratase; GDP-D-mannose dehydratase (rfbD) 41115 6296102 HPSH_00215 Helicobacter pylori Shi470 GDP-D-mannose dehydratase (rfbD) YP_001909540.1 39970 D 512562 CDS YP_001909541.1 188526854 6297176 41108..42040 1 NC_010698.2 COG0451 Nucleoside-diphosphate-sugar epimerases; nodulation protein NolK 42040 6297176 HPSH_00220 Helicobacter pylori Shi470 nodulation protein NolK YP_001909541.1 41108 D 512562 CDS YP_001909542.1 188526855 6296152 complement(42120..42224) 1 NC_010698.2 hypothetical protein 42224 6296152 HPSH_00225 Helicobacter pylori Shi470 hypothetical protein YP_001909542.1 42120 R 512562 CDS YP_001909543.1 188526856 6296201 complement(42325..43323) 1 NC_010698.2 COG0309 Hydrogenase maturation factor; hydrogenase expression/formation protein 43323 6296201 HPSH_00230 Helicobacter pylori Shi470 hydrogenase expression/formation protein YP_001909543.1 42325 R 512562 CDS YP_001909544.1 188526857 6296760 complement(43326..45578) 1 NC_010698.2 COG0068 Hydrogenase maturation factor; transcriptional regulator HypF 45578 6296760 HPSH_00235 Helicobacter pylori Shi470 transcriptional regulator HypF YP_001909544.1 43326 R 512562 CDS YP_001909545.1 188526858 6296765 complement(45575..46567) 1 NC_010698.2 COG2957 Peptidylarginine deiminase and related enzymes; hypothetical protein 46567 6296765 HPSH_00240 Helicobacter pylori Shi470 hypothetical protein YP_001909545.1 45575 R 512562 CDS YP_001909546.1 188526859 6296253 complement(46626..47324) 1 NC_010698.2 COG0863 DNA modification methylase; adenine specific DNA methyltransferase 47324 6296253 HPSH_00245 Helicobacter pylori Shi470 adenine specific DNA methyltransferase YP_001909546.1 46626 R 512562 CDS YP_001909547.1 188526860 6297540 complement(47321..48388) 1 NC_010698.2 COG0270 Site-specific DNA methylase; cytosine specific DNA methyltransferase 48388 6297540 HPSH_00250 Helicobacter pylori Shi470 cytosine specific DNA methyltransferase YP_001909547.1 47321 R 512562 CDS YP_001909548.1 188526861 6297532 complement(48385..48585) 1 NC_010698.2 hypothetical protein 48585 6297532 HPSH_00255 Helicobacter pylori Shi470 hypothetical protein YP_001909548.1 48385 R 512562 CDS YP_001909549.1 188526862 6296170 complement(48613..49611) 1 NC_010698.2 hypothetical protein 49611 6296170 HPSH_00260 Helicobacter pylori Shi470 hypothetical protein YP_001909549.1 48613 R 512562 CDS YP_001909550.1 188526863 6296433 complement(49652..49852) 1 NC_010698.2 adenine/cytosine DNA methyltransferase 49852 6296433 HPSH_00265 Helicobacter pylori Shi470 adenine/cytosine DNA methyltransferase YP_001909550.1 49652 R 512562 CDS YP_001909551.1 188526864 6297152 complement(49833..51332) 1 NC_010698.2 COG0591 Na+/proline symporter; proline permease PutP 51332 6297152 HPSH_00270 Helicobacter pylori Shi470 proline permease PutP YP_001909551.1 49833 R 512562 CDS YP_001909552.1 188526865 6296386 complement(51359..54916) 1 NC_010698.2 COG0506 Proline dehydrogenase; Proline/pyrroline-5-carboxylate dehydrogenase 54916 6296386 HPSH_00275 Helicobacter pylori Shi470 Proline/pyrroline-5-carboxylate dehydrogenase YP_001909552.1 51359 R 512562 CDS YP_001909553.1 188526866 6296359 55244..55453 1 NC_010698.2 hypothetical protein 55453 6296359 HPSH_00280 Helicobacter pylori Shi470 hypothetical protein YP_001909553.1 55244 D 512562 CDS YP_001909554.1 188526867 6296484 55564..55647 1 NC_010698.2 hypothetical protein 55647 6296484 HPSH_00285 Helicobacter pylori Shi470 hypothetical protein YP_001909554.1 55564 D 512562 CDS YP_001909555.1 188526868 6296447 complement(55641..55766) 1 NC_010698.2 hypothetical protein 55766 6296447 HPSH_00290 Helicobacter pylori Shi470 hypothetical protein YP_001909555.1 55641 R 512562 CDS YP_001909556.1 188526869 6296041 55951..56661 1 NC_010698.2 COG5002 Signal transduction histidine kinase; hypothetical protein 56661 6296041 HPSH_00295 Helicobacter pylori Shi470 hypothetical protein YP_001909556.1 55951 D 512562 CDS YP_001909557.1 188526870 6297098 56631..57056 1 NC_010698.2 hypothetical protein 57056 6297098 HPSH_00300 Helicobacter pylori Shi470 hypothetical protein YP_001909557.1 56631 D 512562 CDS YP_001909558.1 188526871 6296578 57058..57408 1 NC_010698.2 hypothetical protein 57408 6296578 HPSH_00305 Helicobacter pylori Shi470 hypothetical protein YP_001909558.1 57058 D 512562 CDS YP_001909559.1 188526872 6296684 complement(59832..60629) 1 NC_010698.2 COG0829 Urease accessory protein UreH; urease accessory protein UreH 60629 6296684 HPSH_00320 Helicobacter pylori Shi470 urease accessory protein UreH YP_001909559.1 59832 R 512562 CDS YP_001909560.1 188526873 6296588 complement(60629..61228) 1 NC_010698.2 COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; urease accessory protein 61228 6296588 HPSH_00325 Helicobacter pylori Shi470 urease accessory protein YP_001909560.1 60629 R 512562 CDS YP_001909561.1 188526874 6296537 complement(61257..62000) 1 NC_010698.2 COG0830 Urease accessory protein UreF; urease accessory protein UreF 62000 6296537 HPSH_00330 Helicobacter pylori Shi470 urease accessory protein UreF YP_001909561.1 61257 R 512562 CDS YP_001909562.1 188526875 6296890 complement(62029..62541) 1 NC_010698.2 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 62541 ureE 6296890 ureE Helicobacter pylori Shi470 urease accessory protein UreE YP_001909562.1 62029 R 512562 CDS YP_001909563.1 188526876 6295991 complement(62543..63130) 1 NC_010698.2 COG1138 Cytochrome c biogenesis factor; urea transporter 63130 6295991 HPSH_00340 Helicobacter pylori Shi470 urea transporter YP_001909563.1 62543 R 512562 CDS YP_001909564.1 188526877 6297438 complement(63198..63308) 1 NC_010698.2 hypothetical protein 63308 6297438 HPSH_00345 Helicobacter pylori Shi470 hypothetical protein YP_001909564.1 63198 R 512562 CDS YP_001909565.1 188526878 6296092 complement(63323..65032) 1 NC_010698.2 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta 65032 ureB 6296092 ureB Helicobacter pylori Shi470 urease subunit beta YP_001909565.1 63323 R 512562 CDS YP_001909566.1 188526879 6296064 complement(65036..65752) 1 NC_010698.2 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha 65752 6296064 HPSH_00355 Helicobacter pylori Shi470 urease subunit alpha YP_001909566.1 65036 R 512562 CDS YP_001909567.1 188526880 6296079 complement(66115..66588) 1 NC_010698.2 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 66588 lspA 6296079 lspA Helicobacter pylori Shi470 lipoprotein signal peptidase YP_001909567.1 66115 R 512562 CDS YP_001909568.1 188526881 6296244 complement(66582..67919) 1 NC_010698.2 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 67919 glmM 6296244 glmM Helicobacter pylori Shi470 phosphoglucosamine mutase YP_001909568.1 66582 R 512562 CDS YP_001909569.1 188526882 6296234 68009..68278 1 NC_010698.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 68278 rpsT 6296234 rpsT Helicobacter pylori Shi470 30S ribosomal protein S20 YP_001909569.1 68009 D 512562 CDS YP_001909570.1 188526883 6296800 68395..69453 1 NC_010698.2 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 69453 prfA 6296800 prfA Helicobacter pylori Shi470 peptide chain release factor 1 YP_001909570.1 68395 D 512562 CDS YP_001909571.1 188526884 6296236 69844..70098 1 NC_010698.2 hypothetical protein 70098 6296236 HPSH_00380 Helicobacter pylori Shi470 hypothetical protein YP_001909571.1 69844 D 512562 CDS YP_001909572.1 188526885 6296491 70176..71417 1 NC_010698.2 outer membrane protein HorA 71417 6296491 HPSH_00385 Helicobacter pylori Shi470 outer membrane protein HorA YP_001909572.1 70176 D 512562 CDS YP_001909573.1 188526886 6296060 71672..73459 1 NC_010698.2 hypothetical protein 73459 6296060 HPSH_00390 Helicobacter pylori Shi470 hypothetical protein YP_001909573.1 71672 D 512562 CDS YP_001909574.1 188526887 6296633 73754..73885 1 NC_010698.2 hypothetical protein 73885 6296633 HPSH_00395 Helicobacter pylori Shi470 hypothetical protein YP_001909574.1 73754 D 512562 CDS YP_001909575.1 188526888 6296328 complement(73889..75910) 1 NC_010698.2 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis transducer TlpC 75910 6296328 HPSH_00400 Helicobacter pylori Shi470 methyl-accepting chemotaxis transducer TlpC YP_001909575.1 73889 R 512562 CDS YP_001909576.1 188526889 6296876 complement(76058..76447) 1 NC_010698.2 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 76447 rpsI 6296876 rpsI Helicobacter pylori Shi470 30S ribosomal protein S9 YP_001909576.1 76058 R 512562 CDS YP_001909577.1 188526890 6297049 complement(76444..76869) 1 NC_010698.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 76869 rplM 6297049 rplM Helicobacter pylori Shi470 50S ribosomal protein L13 YP_001909577.1 76444 R 512562 CDS YP_001909578.1 188526891 6296680 complement(76975..77079) 1 NC_010698.2 hypothetical protein 77079 6296680 HPSH_00415 Helicobacter pylori Shi470 hypothetical protein YP_001909578.1 76975 R 512562 CDS YP_001909579.1 188526892 6296098 complement(77060..77248) 1 NC_010698.2 hypothetical protein 77248 6296098 HPSH_00420 Helicobacter pylori Shi470 hypothetical protein YP_001909579.1 77060 R 512562 CDS YP_001909580.1 188526893 6296945 complement(77255..78601) 1 NC_010698.2 COG0579 Predicted dehydrogenase; malate:quinone oxidoreductase 78601 6296945 HPSH_00425 Helicobacter pylori Shi470 malate:quinone oxidoreductase YP_001909580.1 77255 R 512562 CDS YP_001909581.1 188526894 6296728 complement(78661..80034) 1 NC_010698.2 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 80034 6296728 HPSH_00430 Helicobacter pylori Shi470 hypothetical protein YP_001909581.1 78661 R 512562 CDS YP_001909582.1 188526895 6296239 complement(80054..82039) 1 NC_010698.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 82039 6296239 HPSH_00435 Helicobacter pylori Shi470 RNA polymerase sigma factor RpoD YP_001909582.1 80054 R 512562 CDS YP_001909583.1 188526896 6297289 complement(82230..82925) 1 NC_010698.2 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 82925 6297289 HPSH_00440 Helicobacter pylori Shi470 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001909583.1 82230 R 512562 CDS YP_001909584.1 188526897 6296025 complement(82936..83865) 1 NC_010698.2 COG0331 (acyl-carrier-protein) S-malonyltransferase; malonyl coenzyme A-acyl carrier protein transacylase 83865 6296025 HPSH_00445 Helicobacter pylori Shi470 malonyl coenzyme A-acyl carrier protein transacylase YP_001909584.1 82936 R 512562 CDS YP_001909585.1 188526898 6296323 85119..85952 1 NC_010698.2 COG0863 DNA modification methylase; type I restriction enzyme M protein HsdM 85952 6296323 HPSH_00465 Helicobacter pylori Shi470 type I restriction enzyme M protein HsdM YP_001909585.1 85119 D 512562 CDS YP_001909586.1 188526899 6296442 complement(85970..86860) 1 NC_010698.2 alpha-1,2-fucosyltransferase 86860 6296442 HPSH_00470 Helicobacter pylori Shi470 alpha-1,2-fucosyltransferase YP_001909586.1 85970 R 512562 CDS YP_001909587.1 188526900 6297527 complement(86959..87489) 1 NC_010698.2 hypothetical protein 87489 6297527 HPSH_00475 Helicobacter pylori Shi470 hypothetical protein YP_001909587.1 86959 R 512562 CDS YP_001909588.1 188526901 6296488 87562..88506 1 NC_010698.2 Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 88506 6296488 HPSH_00480 Helicobacter pylori Shi470 2-hydroxyacid dehydrogenase YP_001909588.1 87562 D 512562 CDS YP_001909589.1 188526902 6297509 complement(88834..89547) 1 NC_010698.2 hypothetical protein 89547 6297509 HPSH_00485 Helicobacter pylori Shi470 hypothetical protein YP_001909589.1 88834 R 512562 CDS YP_001909590.1 188526903 6296050 complement(89652..91112) 1 NC_010698.2 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 91112 6296050 HPSH_00490 Helicobacter pylori Shi470 threonine synthase YP_001909590.1 89652 R 512562 CDS YP_001909591.1 188526904 6296051 91315..93351 1 NC_010698.2 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein TlpA 93351 6296051 HPSH_00495 Helicobacter pylori Shi470 methyl-accepting chemotaxis protein TlpA YP_001909591.1 91315 D 512562 CDS YP_001909592.1 188526905 6296352 93351..94457 1 NC_010698.2 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein 94457 6296352 HPSH_00500 Helicobacter pylori Shi470 hypothetical protein YP_001909592.1 93351 D 512562 CDS YP_001909593.1 188526906 6296145 94573..95334 1 NC_010698.2 hypothetical protein 95334 6296145 HPSH_00505 Helicobacter pylori Shi470 hypothetical protein YP_001909593.1 94573 D 512562 CDS YP_001909594.1 188526907 6297233 complement(95317..96099) 1 NC_010698.2 COG0463 Glycosyltransferases involved in cell wall biogenesis; hypothetical protein 96099 6297233 HPSH_00510 Helicobacter pylori Shi470 hypothetical protein YP_001909594.1 95317 R 512562 CDS YP_001909595.1 188526908 6296099 complement(96130..97827) 1 NC_010698.2 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein TlpB 97827 6296099 HPSH_00515 Helicobacter pylori Shi470 methyl-accepting chemotaxis protein TlpB YP_001909595.1 96130 R 512562 CDS YP_001909596.1 188526909 6296516 complement(98036..99781) 1 NC_010698.2 COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; 2',3'-cyclic-nucleotide 2'-phosphodiesterase 99781 6296516 HPSH_00520 Helicobacter pylori Shi470 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_001909596.1 98036 R 512562 CDS YP_001909597.1 188526910 6296483 complement(99921..100388) 1 NC_010698.2 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 100388 6296483 HPSH_00525 Helicobacter pylori Shi470 S-ribosylhomocysteinase YP_001909597.1 99921 R 512562 CDS YP_001909598.1 188526911 6297288 complement(100423..101565) 1 NC_010698.2 catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase/cystathionine beta-lyase 101565 6297288 HPSH_00530 Helicobacter pylori Shi470 cystathionine gamma-synthase/cystathionine beta-lyase YP_001909598.1 100423 R 512562 CDS YP_001909599.1 188526912 6296751 complement(101586..102503) 1 NC_010698.2 COG0031 Cysteine synthase; cysteine synthetase 102503 6296751 HPSH_00535 Helicobacter pylori Shi470 cysteine synthetase YP_001909599.1 101586 R 512562 CDS YP_001909600.1 188526913 6296279 complement(103322..105184) 1 NC_010698.2 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 105184 dnaK 6296279 dnaK Helicobacter pylori Shi470 molecular chaperone DnaK YP_001909600.1 103322 R 512562 CDS YP_001909601.1 188526914 6296268 complement(105215..105790) 1 NC_010698.2 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 105790 6296268 HPSH_00555 Helicobacter pylori Shi470 heat shock protein GrpE YP_001909601.1 105215 R 512562 CDS YP_001909602.1 188526915 6297183 complement(105790..106620) 1 NC_010698.2 Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor 106620 6297183 HPSH_00560 Helicobacter pylori Shi470 heat-inducible transcription repressor YP_001909602.1 105790 R 512562 CDS YP_001909603.1 188526916 6296372 106915..107478 1 NC_010698.2 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; hypothetical protein 107478 6296372 HPSH_00565 Helicobacter pylori Shi470 hypothetical protein YP_001909603.1 106915 D 512562 CDS YP_001909604.1 188526917 6296343 107500..107796 1 NC_010698.2 hypothetical protein 107796 6296343 HPSH_00570 Helicobacter pylori Shi470 hypothetical protein YP_001909604.1 107500 D 512562 CDS YP_001909605.1 188526918 6296807 complement(107821..109704) 1 NC_010698.2 COG2604 Uncharacterized protein conserved in bacteria; hypothetical protein 109704 6296807 HPSH_00575 Helicobacter pylori Shi470 hypothetical protein YP_001909605.1 107821 R 512562 CDS YP_001909606.1 188526919 6296868 complement(109767..111311) 1 NC_010698.2 FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B 111311 6296868 HPSH_00580 Helicobacter pylori Shi470 flagellin B YP_001909606.1 109767 R 512562 CDS YP_001909607.1 188526920 6296047 111477..113687 1 NC_010698.2 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 113687 6296047 HPSH_00585 Helicobacter pylori Shi470 DNA topoisomerase I YP_001909607.1 111477 D 512562 CDS YP_001909608.1 188526921 6296161 113677..114606 1 NC_010698.2 COG0731 Fe-S oxidoreductases; hypothetical protein 114606 6296161 HPSH_00590 Helicobacter pylori Shi470 hypothetical protein YP_001909608.1 113677 D 512562 CDS YP_001909609.1 188526922 6296548 complement(114756..115994) 1 NC_010698.2 hypothetical protein 115994 6296548 HPSH_00595 Helicobacter pylori Shi470 hypothetical protein YP_001909609.1 114756 R 512562 CDS YP_001909610.1 188526923 6296439 complement(116278..117291) 1 NC_010698.2 hypothetical protein 117291 6296439 HPSH_00600 Helicobacter pylori Shi470 hypothetical protein YP_001909610.1 116278 R 512562 CDS YP_001909611.1 188526924 6297484 complement(117391..119829) 1 NC_010698.2 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 119829 6297484 HPSH_00605 Helicobacter pylori Shi470 phosphoenolpyruvate synthase YP_001909611.1 117391 R 512562 CDS YP_001909612.1 188526925 6296324 120035..120148 1 NC_010698.2 hypothetical protein 120148 6296324 HPSH_00610 Helicobacter pylori Shi470 hypothetical protein YP_001909612.1 120035 D 512562 CDS YP_001909613.1 188526926 6296270 120189..122027 1 NC_010698.2 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 122027 thrS 6296270 thrS Helicobacter pylori Shi470 threonyl-tRNA synthetase YP_001909613.1 120189 D 512562 CDS YP_001909614.1 188526927 6296336 122024..122635 1 NC_010698.2 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 122635 infC 6296336 infC Helicobacter pylori Shi470 translation initiation factor IF-3 YP_001909614.1 122024 D 512562 CDS YP_001909615.1 188526928 6296436 122616..122810 1 NC_010698.2 COG0291 Ribosomal protein L35; 50S ribosomal protein L35 122810 rpmI 6296436 rpmI Helicobacter pylori Shi470 50S ribosomal protein L35 YP_001909615.1 122616 D 512562 CDS YP_001909616.1 188526929 6296147 122905..123255 1 NC_010698.2 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 123255 rplT 6296147 rplT Helicobacter pylori Shi470 50S ribosomal protein L20 YP_001909616.1 122905 D 512562 CDS YP_001909617.1 188526930 6296952 123466..124326 1 NC_010698.2 outer membrane protein HorB 124326 6296952 HPSH_00635 Helicobacter pylori Shi470 outer membrane protein HorB YP_001909617.1 123466 D 512562 CDS YP_001909618.1 188526931 6296349 124378..124500 1 NC_010698.2 hypothetical protein 124500 6296349 HPSH_00640 Helicobacter pylori Shi470 hypothetical protein YP_001909618.1 124378 D 512562 CDS YP_001909619.1 188526932 6296477 124678..125109 1 NC_010698.2 hypothetical protein 125109 6296477 HPSH_00645 Helicobacter pylori Shi470 hypothetical protein YP_001909619.1 124678 D 512562 CDS YP_001909620.1 188526933 6296130 125513..126382 1 NC_010698.2 hypothetical protein 126382 6296130 HPSH_00650 Helicobacter pylori Shi470 hypothetical protein YP_001909620.1 125513 D 512562 CDS YP_001909621.1 188526934 6296989 126812..127012 1 NC_010698.2 hypothetical protein 127012 6296989 HPSH_00655 Helicobacter pylori Shi470 hypothetical protein YP_001909621.1 126812 D 512562 CDS YP_001909622.1 188526935 6297031 complement(127248..128615) 1 NC_010698.2 COG1760 L-serine deaminase; L-serine deaminase 128615 6297031 HPSH_00660 Helicobacter pylori Shi470 L-serine deaminase YP_001909622.1 127248 R 512562 CDS YP_001909623.1 188526936 6296541 complement(128615..129856) 1 NC_010698.2 COG0814 Amino acid permeases; hypothetical protein 129856 6296541 HPSH_00665 Helicobacter pylori Shi470 hypothetical protein YP_001909623.1 128615 R 512562 CDS YP_001909624.1 188526937 6296318 129919..130011 1 NC_010698.2 hypothetical protein 130011 6296318 HPSH_00670 Helicobacter pylori Shi470 hypothetical protein YP_001909624.1 129919 D 512562 CDS YP_001909625.1 188526938 6296539 130038..131387 1 NC_010698.2 COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; tyrosine-regulated 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 131387 6296539 HPSH_00675 Helicobacter pylori Shi470 tyrosine-regulated 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase YP_001909625.1 130038 D 512562 CDS YP_001909626.1 188526939 6296473 131466..131600 1 NC_010698.2 hypothetical protein 131600 6296473 HPSH_00680 Helicobacter pylori Shi470 hypothetical protein YP_001909626.1 131466 D 512562 CDS YP_001909627.1 188526940 6296465 complement(131829..132287) 1 NC_010698.2 COG1225 Peroxiredoxin; bacterioferritin comigratory protein 132287 6296465 HPSH_00685 Helicobacter pylori Shi470 bacterioferritin comigratory protein YP_001909627.1 131829 R 512562 CDS YP_001909628.1 188526941 6296503 complement(132297..132932) 1 NC_010698.2 COG1556 Uncharacterized conserved protein; hypothetical protein 132932 6296503 HPSH_00690 Helicobacter pylori Shi470 hypothetical protein YP_001909628.1 132297 R 512562 CDS YP_001909629.1 188526942 6296002 complement(132925..134370) 1 NC_010698.2 COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain; iron-sulfur protein 134370 6296002 HPSH_00695 Helicobacter pylori Shi470 iron-sulfur protein YP_001909629.1 132925 R 512562 CDS YP_001909630.1 188526943 6296331 complement(134399..135127) 1 NC_010698.2 COG0247 Fe-S oxidoreductase; hypothetical protein 135127 6296331 HPSH_00700 Helicobacter pylori Shi470 hypothetical protein YP_001909630.1 134399 R 512562 CDS YP_001909631.1 188526944 6296456 135348..136997 1 NC_010698.2 COG1620 L-lactate permease; L-lactate permease 136997 6296456 HPSH_00705 Helicobacter pylori Shi470 L-lactate permease YP_001909631.1 135348 D 512562 CDS YP_001909632.1 188526945 6296344 137046..138701 1 NC_010698.2 COG1620 L-lactate permease; L-lactate permease 138701 6296344 HPSH_00710 Helicobacter pylori Shi470 L-lactate permease YP_001909632.1 137046 D 512562 CDS YP_001909633.1 188526946 6296046 complement(138725..139594) 1 NC_010698.2 COG1194 A/G-specific DNA glycosylase; DNA glycosylase MutY 139594 6296046 HPSH_00715 Helicobacter pylori Shi470 DNA glycosylase MutY YP_001909633.1 138725 R 512562 CDS YP_001909634.1 188526947 6296406 complement(139712..141160) 1 NC_010698.2 COG0471 Di- and tricarboxylate transporters; C(4)-dicarboxylates and tricarboxylates/succinate antiporter 141160 6296406 HPSH_00720 Helicobacter pylori Shi470 C(4)-dicarboxylates and tricarboxylates/succinate antiporter YP_001909634.1 139712 R 512562 CDS YP_001909635.1 188526948 6296472 141330..142796 1 NC_010698.2 CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 142796 6296472 HPSH_00725 Helicobacter pylori Shi470 cbb3-type cytochrome c oxidase subunit I YP_001909635.1 141330 D 512562 CDS YP_001909636.1 188526949 6296356 142809..143507 1 NC_010698.2 CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 143507 6296356 HPSH_00730 Helicobacter pylori Shi470 cbb3-type cytochrome c oxidase subunit II YP_001909636.1 142809 D 512562 CDS YP_001909637.1 188526950 6296431 143518..143736 1 NC_010698.2 cbb3-type cytochrome c oxidase subunit Q CcoQ 143736 6296431 HPSH_00735 Helicobacter pylori Shi470 cbb3-type cytochrome c oxidase subunit Q CcoQ YP_001909637.1 143518 D 512562 CDS YP_001909638.1 188526951 6296740 143738..144616 1 NC_010698.2 COG2010 Cytochrome c, mono- and diheme variants; cytochrome c oxidase diheme subunit 144616 6296740 HPSH_00740 Helicobacter pylori Shi470 cytochrome c oxidase diheme subunit YP_001909638.1 143738 D 512562 CDS YP_001909639.1 188526952 6296292 144627..144833 1 NC_010698.2 hypothetical protein 144833 6296292 HPSH_00745 Helicobacter pylori Shi470 hypothetical protein YP_001909639.1 144627 D 512562 CDS YP_001909640.1 188526953 6296766 144830..144937 1 NC_010698.2 hypothetical protein 144937 6296766 HPSH_00750 Helicobacter pylori Shi470 hypothetical protein YP_001909640.1 144830 D 512562 CDS YP_001909641.1 188526954 6296429 144973..145518 1 NC_010698.2 COG0443 Molecular chaperone; hypothetical protein 145518 6296429 HPSH_00755 Helicobacter pylori Shi470 hypothetical protein YP_001909641.1 144973 D 512562 CDS YP_001909642.1 188526955 6296818 145530..146111 1 NC_010698.2 hypothetical protein 146111 6296818 HPSH_00760 Helicobacter pylori Shi470 hypothetical protein YP_001909642.1 145530 D 512562 CDS YP_001909643.1 188526956 6296476 146200..146967 1 NC_010698.2 hypothetical protein 146967 6296476 HPSH_00765 Helicobacter pylori Shi470 hypothetical protein YP_001909643.1 146200 D 512562 CDS YP_001909644.1 188526957 6296495 complement(146964..147830) 1 NC_010698.2 COG2107 Predicted periplasmic solute-binding protein; hypothetical protein 147830 6296495 HPSH_00770 Helicobacter pylori Shi470 hypothetical protein YP_001909644.1 146964 R 512562 CDS YP_001909645.1 188526958 6296515 147929..148972 1 NC_010698.2 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 148972 recA 6296515 recA Helicobacter pylori Shi470 recombinase A YP_001909645.1 147929 D 512562 CDS YP_001909646.1 188526959 6296811 148984..150264 1 NC_010698.2 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 150264 eno 6296811 eno Helicobacter pylori Shi470 phosphopyruvate hydratase YP_001909646.1 148984 D 512562 CDS YP_001909647.1 188526960 6295995 150257..150532 1 NC_010698.2 hypothetical protein 150532 6295995 HPSH_00785 Helicobacter pylori Shi470 hypothetical protein YP_001909647.1 150257 D 512562 CDS YP_001909648.1 188526961 6296317 150548..151144 1 NC_010698.2 hypothetical protein 151144 6296317 HPSH_00790 Helicobacter pylori Shi470 hypothetical protein YP_001909648.1 150548 D 512562 CDS YP_001909649.1 188526962 6296222 151149..151637 1 NC_010698.2 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 151637 aroK 6296222 aroK Helicobacter pylori Shi470 shikimate kinase YP_001909649.1 151149 D 512562 CDS YP_001909650.1 188526963 6296131 151658..152614 1 NC_010698.2 hypothetical protein 152614 6296131 HPSH_00800 Helicobacter pylori Shi470 hypothetical protein YP_001909650.1 151658 D 512562 CDS YP_001909651.1 188526964 6296167 complement(152611..153723) 1 NC_010698.2 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; putative lipopolysaccharide biosynthesis protein 153723 6296167 HPSH_00805 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001909651.1 152611 R 512562 CDS YP_001909652.1 188526965 6296859 153874..154791 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 154791 6296859 HPSH_00810 Helicobacter pylori Shi470 hypothetical protein YP_001909652.1 153874 D 512562 CDS YP_001909653.1 188526966 6296711 complement(155240..155371) 1 NC_010698.2 hypothetical protein 155371 6296711 HPSH_00815 Helicobacter pylori Shi470 hypothetical protein YP_001909653.1 155240 R 512562 CDS YP_001909654.1 188526967 6296211 complement(155550..156272) 1 NC_010698.2 COG0217 Uncharacterized conserved protein; hypothetical protein 156272 6296211 HPSH_00820 Helicobacter pylori Shi470 hypothetical protein YP_001909654.1 155550 R 512562 CDS YP_001909655.1 188526968 6296412 complement(156273..157244) 1 NC_010698.2 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 157244 6296412 HPSH_00825 Helicobacter pylori Shi470 delta-aminolevulinic acid dehydratase YP_001909655.1 156273 R 512562 CDS YP_001909656.1 188526969 6297186 complement(157267..158598) 1 NC_010698.2 COG0642 Signal transduction histidine kinase; putative histidine kinase sensor protein 158598 6297186 HPSH_00830 Helicobacter pylori Shi470 putative histidine kinase sensor protein YP_001909656.1 157267 R 512562 CDS YP_001909657.1 188526970 6297272 complement(158624..159301) 1 NC_010698.2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator OmpR 159301 6297272 HPSH_00835 Helicobacter pylori Shi470 response regulator OmpR YP_001909657.1 158624 R 512562 CDS YP_001909658.1 188526971 6296518 complement(159535..159999) 1 NC_010698.2 hypothetical protein 159999 6296518 HPSH_00840 Helicobacter pylori Shi470 hypothetical protein YP_001909658.1 159535 R 512562 CDS YP_001909659.1 188526972 6296035 complement(159990..160253) 1 NC_010698.2 COG0457 FOG: TPR repeat; hypothetical protein 160253 6296035 HPSH_00845 Helicobacter pylori Shi470 hypothetical protein YP_001909659.1 159990 R 512562 CDS YP_001909660.1 188526973 6296309 complement(160286..161566) 1 NC_010698.2 COG0826 Collagenase and related proteases; collagenase 161566 6296309 HPSH_00850 Helicobacter pylori Shi470 collagenase YP_001909660.1 160286 R 512562 CDS YP_001909661.1 188526974 6296217 complement(161569..162288) 1 NC_010698.2 hypothetical protein 162288 6296217 HPSH_00855 Helicobacter pylori Shi470 hypothetical protein YP_001909661.1 161569 R 512562 CDS YP_001909662.1 188526975 6296320 complement(162363..163454) 1 NC_010698.2 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 163454 prfB 6296320 prfB Helicobacter pylori Shi470 peptide chain release factor 2 YP_001909662.1 162363 R 512562 CDS YP_001909663.1 188526976 6296394 complement(163515..164690) 1 NC_010698.2 COG0303 Molybdopterin biosynthesis enzyme; molybdopterin biosynthesis protein MoeA 164690 6296394 HPSH_00865 Helicobacter pylori Shi470 molybdopterin biosynthesis protein MoeA YP_001909663.1 163515 R 512562 CDS YP_001909664.1 188526977 6296467 complement(164700..165467) 1 NC_010698.2 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 165467 fliR 6296467 fliR Helicobacter pylori Shi470 flagellar biosynthesis protein FliR YP_001909664.1 164700 R 512562 CDS YP_001909665.1 188526978 6296315 complement(165442..166188) 1 NC_010698.2 hypothetical protein 166188 6296315 HPSH_00875 Helicobacter pylori Shi470 hypothetical protein YP_001909665.1 165442 R 512562 CDS YP_001909666.1 188526979 6296479 166669..167568 1 NC_010698.2 COG0760 Parvulin-like peptidyl-prolyl isomerase; putative peptidyl-prolyl cis-trans isomerase 167568 6296479 HPSH_00880 Helicobacter pylori Shi470 putative peptidyl-prolyl cis-trans isomerase YP_001909666.1 166669 D 512562 CDS YP_001909667.1 188526980 6296538 167585..168508 1 NC_010698.2 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 168508 6296538 HPSH_00885 Helicobacter pylori Shi470 fructose-bisphosphate aldolase YP_001909667.1 167585 D 512562 CDS YP_001909668.1 188526981 6297388 168530..169093 1 NC_010698.2 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 169093 6297388 HPSH_00890 Helicobacter pylori Shi470 elongation factor P YP_001909668.1 168530 D 512562 CDS YP_001909669.1 188526982 6296559 169315..169437 1 NC_010698.2 hypothetical protein 169437 6296559 HPSH_00895 Helicobacter pylori Shi470 hypothetical protein YP_001909669.1 169315 D 512562 CDS YP_001909670.1 188526983 6296614 complement(169636..170658) 1 NC_010698.2 COG2089 Sialic acid synthase; sialic acid synthase 170658 6296614 HPSH_00900 Helicobacter pylori Shi470 sialic acid synthase YP_001909670.1 169636 R 512562 CDS YP_001909671.1 188526984 6296523 complement(170662..171303) 1 NC_010698.2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 171303 6296523 HPSH_00905 Helicobacter pylori Shi470 ABC transporter ATP-binding protein YP_001909671.1 170662 R 512562 CDS YP_001909672.1 188526985 6296530 complement(171303..172577) 1 NC_010698.2 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 172577 6296530 HPSH_00910 Helicobacter pylori Shi470 apolipoprotein N-acyltransferase YP_001909672.1 171303 R 512562 CDS YP_001909673.1 188526986 6296761 172678..172830 1 NC_010698.2 hypothetical protein 172830 6296761 HPSH_00915 Helicobacter pylori Shi470 hypothetical protein YP_001909673.1 172678 D 512562 CDS YP_001909674.1 188526987 6296141 172827..173528 1 NC_010698.2 COG1286 Uncharacterized membrane protein, required for colicin V production; hypothetical protein 173528 6296141 HPSH_00920 Helicobacter pylori Shi470 hypothetical protein YP_001909674.1 172827 D 512562 CDS YP_001909675.1 188526988 6297477 173538..175043 1 NC_010698.2 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 175043 lysS 6297477 lysS Helicobacter pylori Shi470 lysyl-tRNA synthetase YP_001909675.1 173538 D 512562 CDS YP_001909676.1 188526989 6296460 175043..176293 1 NC_010698.2 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 176293 glyA 6296460 glyA Helicobacter pylori Shi470 serine hydroxymethyltransferase YP_001909676.1 175043 D 512562 CDS YP_001909677.1 188526990 6296420 176304..176846 1 NC_010698.2 hypothetical protein 176846 6296420 HPSH_00935 Helicobacter pylori Shi470 hypothetical protein YP_001909677.1 176304 D 512562 CDS YP_001909678.1 188526991 6296049 176868..177677 1 NC_010698.2 hypothetical protein 177677 6296049 HPSH_00940 Helicobacter pylori Shi470 hypothetical protein YP_001909678.1 176868 D 512562 CDS YP_001909679.1 188526992 6297225 complement(177878..178063) 1 NC_010698.2 hypothetical protein 178063 6297225 HPSH_00945 Helicobacter pylori Shi470 hypothetical protein YP_001909679.1 177878 R 512562 CDS YP_001909680.1 188526993 6296326 complement(179667..179768) 1 NC_010698.2 COG1479 Uncharacterized conserved protein; hypothetical protein 179768 6296326 HPSH_00965 Helicobacter pylori Shi470 hypothetical protein YP_001909680.1 179667 R 512562 CDS YP_001909681.1 188526994 6296364 179931..180467 1 NC_010698.2 COG2862 Predicted membrane protein; hypothetical protein 180467 6296364 HPSH_00970 Helicobacter pylori Shi470 hypothetical protein YP_001909681.1 179931 D 512562 CDS YP_001909682.1 188526995 6296936 complement(180473..181981) 1 NC_010698.2 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; hypothetical protein 181981 6296936 HPSH_00975 Helicobacter pylori Shi470 hypothetical protein YP_001909682.1 180473 R 512562 CDS YP_001909683.1 188526996 6296863 complement(182003..182740) 1 NC_010698.2 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 182740 frdB 6296863 frdB Helicobacter pylori Shi470 fumarate reductase iron-sulfur subunit YP_001909683.1 182003 R 512562 CDS YP_001909684.1 188526997 6297003 complement(182733..184877) 1 NC_010698.2 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 184877 6297003 HPSH_00985 Helicobacter pylori Shi470 fumarate reductase flavoprotein subunit YP_001909684.1 182733 R 512562 CDS YP_001909685.1 188526998 6296287 complement(184887..185654) 1 NC_010698.2 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit 185654 6296287 HPSH_00990 Helicobacter pylori Shi470 fumarate reductase cytochrome b-556 subunit YP_001909685.1 184887 R 512562 CDS YP_001909686.1 188526999 6297505 185868..186572 1 NC_010698.2 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 186572 tpiA 6297505 tpiA Helicobacter pylori Shi470 triosephosphate isomerase YP_001909686.1 185868 D 512562 CDS YP_001909687.1 188527000 6296115 186582..187409 1 NC_010698.2 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 187409 6296115 HPSH_01000 Helicobacter pylori Shi470 enoyl-(acyl carrier protein) reductase YP_001909687.1 186582 D 512562 CDS YP_001909688.1 188527001 6297005 187419..188429 1 NC_010698.2 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 188429 lpxD 6297005 lpxD Helicobacter pylori Shi470 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001909688.1 187419 D 512562 CDS YP_001909689.1 188527002 6296086 188494..189651 1 NC_010698.2 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 189651 6296086 HPSH_01010 Helicobacter pylori Shi470 S-adenosylmethionine synthetase YP_001909689.1 188494 D 512562 CDS YP_001909690.1 188527003 6297459 189718..190131 1 NC_010698.2 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 190131 ndk 6297459 ndk Helicobacter pylori Shi470 nucleoside diphosphate kinase YP_001909690.1 189718 D 512562 CDS YP_001909691.1 188527004 6296038 190156..190512 1 NC_010698.2 hypothetical protein 190512 6296038 HPSH_01020 Helicobacter pylori Shi470 hypothetical protein YP_001909691.1 190156 D 512562 CDS YP_001909692.1 188527005 6296470 190528..190674 1 NC_010698.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 190674 rpmF 6296470 rpmF Helicobacter pylori Shi470 50S ribosomal protein L32 YP_001909692.1 190528 D 512562 CDS YP_001909693.1 188527006 6296275 190742..191761 1 NC_010698.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 191761 6296275 HPSH_01030 Helicobacter pylori Shi470 putative glycerol-3-phosphate acyltransferase PlsX YP_001909693.1 190742 D 512562 CDS YP_001909694.1 188527007 6296199 191785..192780 1 NC_010698.2 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 192780 6296199 HPSH_01035 Helicobacter pylori Shi470 3-oxoacyl-(acyl carrier protein) synthase III YP_001909694.1 191785 D 512562 CDS YP_001909695.1 188527008 6296280 192802..193104 1 NC_010698.2 hypothetical protein 193104 6296280 HPSH_01040 Helicobacter pylori Shi470 hypothetical protein YP_001909695.1 192802 D 512562 CDS YP_001909696.1 188527009 6296329 complement(193388..193771) 1 NC_010698.2 hypothetical protein 193771 6296329 HPSH_01045 Helicobacter pylori Shi470 hypothetical protein YP_001909696.1 193388 R 512562 CDS YP_001909697.1 188527010 6296063 197050..198156 1 NC_010698.2 COG0489 ATPases involved in chromosome partitioning; ATP-binding protein 198156 6296063 HPSH_01065 Helicobacter pylori Shi470 ATP-binding protein YP_001909697.1 197050 D 512562 CDS YP_001909698.1 188527011 6296273 complement(198172..199191) 1 NC_010698.2 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glycosyltransferase 199191 6296273 HPSH_01070 Helicobacter pylori Shi470 lipopolysaccharide 1,2-glycosyltransferase YP_001909698.1 198172 R 512562 CDS YP_001909699.1 188527012 6296510 complement(199215..199328) 1 NC_010698.2 lipopolysaccharide 1,2-glycosyltransferase 199328 6296510 HPSH_01075 Helicobacter pylori Shi470 lipopolysaccharide 1,2-glycosyltransferase YP_001909699.1 199215 R 512562 CDS YP_001909700.1 188527013 6296195 199437..200840 1 NC_010698.2 hypothetical protein 200840 6296195 HPSH_01080 Helicobacter pylori Shi470 hypothetical protein YP_001909700.1 199437 D 512562 CDS YP_001909701.1 188527014 6297118 200943..202808 1 NC_010698.2 molecular chaperone; heat shock protein 90 202808 6297118 HPSH_01085 Helicobacter pylori Shi470 heat shock protein 90 YP_001909701.1 200943 D 512562 CDS YP_001909702.1 188527015 6296227 complement(203212..203964) 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein A 203964 6296227 HPSH_01090 Helicobacter pylori Shi470 cysteine-rich protein A YP_001909702.1 203212 R 512562 CDS YP_001909703.1 188527016 6296462 complement(204050..205201) 1 NC_010698.2 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 205201 6296462 HPSH_01095 Helicobacter pylori Shi470 succinyl-diaminopimelate desuccinylase YP_001909703.1 204050 R 512562 CDS YP_001909704.1 188527017 6296384 complement(205212..207077) 1 NC_010698.2 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 207077 6296384 HPSH_01100 Helicobacter pylori Shi470 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001909704.1 205212 R 512562 CDS YP_001909705.1 188527018 6296430 207173..208831 1 NC_010698.2 COG0471 Di- and tricarboxylate transporters; sodium-dependent transporter 208831 6296430 HPSH_01105 Helicobacter pylori Shi470 sodium-dependent transporter YP_001909705.1 207173 D 512562 CDS YP_001909706.1 188527019 6296377 208844..209644 1 NC_010698.2 COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthetase CdsA 209644 6296377 HPSH_01110 Helicobacter pylori Shi470 CDP-diglyceride synthetase CdsA YP_001909706.1 208844 D 512562 CDS YP_001909707.1 188527020 6296056 209645..210751 1 NC_010698.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 210751 6296056 HPSH_01115 Helicobacter pylori Shi470 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001909707.1 209645 D 512562 CDS YP_001909708.1 188527021 6296097 210802..211098 1 NC_010698.2 hypothetical protein 211098 6296097 HPSH_01120 Helicobacter pylori Shi470 hypothetical protein YP_001909708.1 210802 D 512562 CDS YP_001909709.1 188527022 6295994 211146..211940 1 NC_010698.2 hypothetical protein 211940 6295994 HPSH_01125 Helicobacter pylori Shi470 hypothetical protein YP_001909709.1 211146 D 512562 CDS YP_001909710.1 188527023 6297445 complement(211956..212540) 1 NC_010698.2 COG1881 Phospholipid-binding protein; phospholipid-binding protein 212540 6297445 HPSH_01130 Helicobacter pylori Shi470 phospholipid-binding protein YP_001909710.1 211956 R 512562 CDS YP_001909711.1 188527024 6296032 212652..213113 1 NC_010698.2 hypothetical protein 213113 6296032 HPSH_01135 Helicobacter pylori Shi470 hypothetical protein YP_001909711.1 212652 D 512562 CDS YP_001909712.1 188527025 6296733 213286..214449 1 NC_010698.2 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine desulfurase 214449 6296733 HPSH_01140 Helicobacter pylori Shi470 cysteine desulfurase YP_001909712.1 213286 D 512562 CDS YP_001909713.1 188527026 6296096 214471..215451 1 NC_010698.2 COG0822 NifU homolog involved in Fe-S cluster formation; nifU-like protein 215451 6296096 HPSH_01145 Helicobacter pylori Shi470 nifU-like protein YP_001909713.1 214471 D 512562 CDS YP_001909714.1 188527027 6296095 215626..215859 1 NC_010698.2 hypothetical protein 215859 6296095 HPSH_01150 Helicobacter pylori Shi470 hypothetical protein YP_001909714.1 215626 D 512562 CDS YP_001909715.1 188527028 6296564 215972..217318 1 NC_010698.2 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 217318 6296564 HPSH_01155 Helicobacter pylori Shi470 DNA repair protein RadA YP_001909715.1 215972 D 512562 CDS YP_001909716.1 188527029 6296173 217455..218492 1 NC_010698.2 COG0225 Peptide methionine sulfoxide reductase; bifunctional methionine sulfoxide reductase A/B protein 218492 6296173 HPSH_01160 Helicobacter pylori Shi470 bifunctional methionine sulfoxide reductase A/B protein YP_001909716.1 217455 D 512562 CDS YP_001909717.1 188527030 6296891 218739..218825 1 NC_010698.2 hypothetical protein 218825 6296891 HPSH_01165 Helicobacter pylori Shi470 hypothetical protein YP_001909717.1 218739 D 512562 CDS YP_001909718.1 188527031 6296504 complement(218946..219779) 1 NC_010698.2 COG0730 Predicted permeases; hypothetical protein 219779 6296504 HPSH_01170 Helicobacter pylori Shi470 hypothetical protein YP_001909718.1 218946 R 512562 CDS YP_001909719.1 188527032 6296637 complement(219805..219963) 1 NC_010698.2 hypothetical protein 219963 6296637 HPSH_01175 Helicobacter pylori Shi470 hypothetical protein YP_001909719.1 219805 R 512562 CDS YP_001909720.1 188527033 6296981 complement(219985..222072) 1 NC_010698.2 putative Outer membrane protein 222072 6296981 HPSH_01180 Helicobacter pylori Shi470 putative Outer membrane protein YP_001909720.1 219985 R 512562 CDS YP_001909721.1 188527034 6296572 222329..223486 1 NC_010698.2 COG0659 Sulfate permease and related transporters (MFS superfamily); putative sulfate permease 223486 6296572 HPSH_01185 Helicobacter pylori Shi470 putative sulfate permease YP_001909721.1 222329 D 512562 CDS YP_001909722.1 188527035 6296656 complement(223726..225147) 1 NC_010698.2 outer membrane protein 225147 6296656 HPSH_01190 Helicobacter pylori Shi470 outer membrane protein YP_001909722.1 223726 R 512562 CDS YP_001909723.1 188527036 6296363 complement(225372..226097) 1 NC_010698.2 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 226097 6296363 HPSH_01195 Helicobacter pylori Shi470 3-deoxy-manno-octulosonate cytidylyltransferase YP_001909723.1 225372 R 512562 CDS YP_001909724.1 188527037 6296193 226210..227007 1 NC_010698.2 COG1651 Protein-disulfide isomerase; hypothetical protein 227007 6296193 HPSH_01200 Helicobacter pylori Shi470 hypothetical protein YP_001909724.1 226210 D 512562 CDS YP_001909725.1 188527038 6296120 227023..227676 1 NC_010698.2 hypothetical protein 227676 6296120 HPSH_01205 Helicobacter pylori Shi470 hypothetical protein YP_001909725.1 227023 D 512562 CDS YP_001909726.1 188527039 6296156 227701..228873 1 NC_010698.2 COG0754 Glutathionylspermidine synthase; hypothetical protein 228873 6296156 HPSH_01210 Helicobacter pylori Shi470 hypothetical protein YP_001909726.1 227701 D 512562 CDS YP_001909727.1 188527040 6296400 228885..229403 1 NC_010698.2 hypothetical protein 229403 6296400 HPSH_01215 Helicobacter pylori Shi470 hypothetical protein YP_001909727.1 228885 D 512562 CDS YP_001909728.1 188527041 6296374 229499..229576 1 NC_010698.2 hypothetical protein 229576 6296374 HPSH_01220 Helicobacter pylori Shi470 hypothetical protein YP_001909728.1 229499 D 512562 CDS YP_001909729.1 188527042 6296062 complement(229851..230918) 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein E 230918 6296062 HPSH_01225 Helicobacter pylori Shi470 cysteine-rich protein E YP_001909729.1 229851 R 512562 CDS YP_001909730.1 188527043 6296582 complement(231012..231380) 1 NC_010698.2 hypothetical protein 231380 6296582 HPSH_01230 Helicobacter pylori Shi470 hypothetical protein YP_001909730.1 231012 R 512562 CDS YP_001909731.1 188527044 6296459 complement(231380..232300) 1 NC_010698.2 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 232300 hemC 6296459 hemC Helicobacter pylori Shi470 porphobilinogen deaminase YP_001909731.1 231380 R 512562 CDS YP_001909732.1 188527045 6296415 complement(232311..234044) 1 NC_010698.2 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 234044 6296415 HPSH_01240 Helicobacter pylori Shi470 prolyl-tRNA synthetase YP_001909732.1 232311 R 512562 CDS YP_001909733.1 188527046 6297082 complement(234048..235397) 1 NC_010698.2 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 235397 hemA 6297082 hemA Helicobacter pylori Shi470 glutamyl-tRNA reductase YP_001909733.1 234048 R 512562 CDS YP_001909734.1 188527047 6296369 complement(235397..236320) 1 NC_010698.2 COG0142 Geranylgeranyl pyrophosphate synthase; putative octaprenyl-diphosphate synthase 236320 6296369 HPSH_01250 Helicobacter pylori Shi470 putative octaprenyl-diphosphate synthase YP_001909734.1 235397 R 512562 CDS YP_001909735.1 188527048 6296461 complement(236330..236725) 1 NC_010698.2 hypothetical protein 236725 6296461 HPSH_01255 Helicobacter pylori Shi470 hypothetical protein YP_001909735.1 236330 R 512562 CDS YP_001909736.1 188527049 6297426 complement(236718..237002) 1 NC_010698.2 hypothetical protein 237002 6297426 HPSH_01260 Helicobacter pylori Shi470 hypothetical protein YP_001909736.1 236718 R 512562 CDS YP_001909737.1 188527050 6296517 complement(237023..237457) 1 NC_010698.2 COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); neutrophil activating protein NapA 237457 6296517 HPSH_01265 Helicobacter pylori Shi470 neutrophil activating protein NapA YP_001909737.1 237023 R 512562 CDS YP_001909738.1 188527051 6297465 complement(237662..238807) 1 NC_010698.2 COG0642 Signal transduction histidine kinase; histidine kinase sensor protein 238807 6297465 HPSH_01270 Helicobacter pylori Shi470 histidine kinase sensor protein YP_001909738.1 237662 R 512562 CDS YP_001909739.1 188527052 6296367 complement(238804..239121) 1 NC_010698.2 hypothetical protein 239121 6296367 HPSH_01275 Helicobacter pylori Shi470 hypothetical protein YP_001909739.1 238804 R 512562 CDS YP_001909740.1 188527053 6296075 complement(239118..240137) 1 NC_010698.2 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 240137 flgI 6296075 flgI Helicobacter pylori Shi470 flagellar basal body P-ring protein YP_001909740.1 239118 R 512562 CDS YP_001909741.1 188527054 6296037 240335..241813 1 NC_010698.2 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase 241813 6296037 HPSH_01285 Helicobacter pylori Shi470 ATP-dependent RNA helicase YP_001909741.1 240335 D 512562 CDS YP_001909742.1 188527055 6296445 241834..242922 1 NC_010698.2 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 242922 6296445 HPSH_01290 Helicobacter pylori Shi470 hypothetical protein YP_001909742.1 241834 D 512562 CDS YP_001909743.1 188527056 6296154 242929..243468 1 NC_010698.2 hypothetical protein 243468 6296154 HPSH_01295 Helicobacter pylori Shi470 hypothetical protein YP_001909743.1 242929 D 512562 CDS YP_001909744.1 188527057 6296402 complement(243532..245082) 1 NC_010698.2 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; oligopeptide permease ATPase 245082 6296402 HPSH_01300 Helicobacter pylori Shi470 oligopeptide permease ATPase YP_001909744.1 243532 R 512562 CDS YP_001909745.1 188527058 6296432 complement(245092..246114) 1 NC_010698.2 COG4239 ABC-type uncharacterized transport system, permease component; oligopeptide permease integral membrane protein 246114 6296432 HPSH_01305 Helicobacter pylori Shi470 oligopeptide permease integral membrane protein YP_001909745.1 245092 R 512562 CDS YP_001909746.1 188527059 6297478 246400..246498 1 NC_010698.2 hypothetical protein 246498 6297478 HPSH_01310 Helicobacter pylori Shi470 hypothetical protein YP_001909746.1 246400 D 512562 CDS YP_001909747.1 188527060 6297491 246479..247900 1 NC_010698.2 outer membrane protein 247900 6297491 HPSH_01315 Helicobacter pylori Shi470 outer membrane protein YP_001909747.1 246479 D 512562 CDS YP_001909748.1 188527061 6297036 247952..249331 1 NC_010698.2 outer membrane protein HopG 249331 6297036 HPSH_01320 Helicobacter pylori Shi470 outer membrane protein HopG YP_001909748.1 247952 D 512562 CDS YP_001909749.1 188527062 6297162 249430..250665 1 NC_010698.2 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 250665 6297162 HPSH_01325 Helicobacter pylori Shi470 adenylosuccinate synthetase YP_001909749.1 249430 D 512562 CDS YP_001909750.1 188527063 6296927 250662..251090 1 NC_010698.2 hypothetical protein 251090 6296927 HPSH_01330 Helicobacter pylori Shi470 hypothetical protein YP_001909750.1 250662 D 512562 CDS YP_001909751.1 188527064 6296662 251083..251742 1 NC_010698.2 COG3334 Uncharacterized conserved protein; hypothetical protein 251742 6296662 HPSH_01335 Helicobacter pylori Shi470 hypothetical protein YP_001909751.1 251083 D 512562 CDS YP_001909752.1 188527065 6296353 251739..252794 1 NC_010698.2 COG0750 Predicted membrane-associated Zn-dependent proteases 1; hypothetical protein 252794 6296353 HPSH_01340 Helicobacter pylori Shi470 hypothetical protein YP_001909752.1 251739 D 512562 CDS YP_001909753.1 188527066 6296715 252807..254069 1 NC_010698.2 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 254069 xseA 6296715 xseA Helicobacter pylori Shi470 exodeoxyribonuclease VII large subunit YP_001909753.1 252807 D 512562 CDS YP_001909754.1 188527067 6296434 complement(254088..255260) 1 NC_010698.2 COG2189 Adenine specific DNA methylase Mod; type II DNA modification methyltransferase 255260 6296434 HPSH_01350 Helicobacter pylori Shi470 type II DNA modification methyltransferase YP_001909754.1 254088 R 512562 CDS YP_001909755.1 188527068 6297541 256055..256750 1 NC_010698.2 endonuclease MjaVIP 256750 6297541 HPSH_01365 Helicobacter pylori Shi470 endonuclease MjaVIP YP_001909755.1 256055 D 512562 CDS YP_001909756.1 188527069 6296091 256747..257505 1 NC_010698.2 COG0863 DNA modification methylase; adenine specific DNA methyltransferase 257505 6296091 HPSH_01370 Helicobacter pylori Shi470 adenine specific DNA methyltransferase YP_001909756.1 256747 D 512562 CDS YP_001909757.1 188527070 6296000 257578..260148 1 NC_010698.2 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent protease binding subunit ClpB 260148 6296000 HPSH_01375 Helicobacter pylori Shi470 ATP-dependent protease binding subunit ClpB YP_001909757.1 257578 D 512562 CDS YP_001909758.1 188527071 6296450 260205..260924 1 NC_010698.2 COG0785 Cytochrome c biogenesis protein; cytochrome c biogenesis protein 260924 6296450 HPSH_01380 Helicobacter pylori Shi470 cytochrome c biogenesis protein YP_001909758.1 260205 D 512562 CDS YP_001909759.1 188527072 6296011 260934..262070 1 NC_010698.2 COG0044 Dihydroorotase and related cyclic amidohydrolases; dihydroorotase PyrC 262070 6296011 HPSH_01385 Helicobacter pylori Shi470 dihydroorotase PyrC YP_001909759.1 260934 D 512562 CDS YP_001909760.1 188527073 6296058 262055..263284 1 NC_010698.2 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 263284 6296058 HPSH_01390 Helicobacter pylori Shi470 chlorohydrolase YP_001909760.1 262055 D 512562 CDS YP_001909761.1 188527074 6296181 263345..263587 1 NC_010698.2 hypothetical protein 263587 6296181 HPSH_01395 Helicobacter pylori Shi470 hypothetical protein YP_001909761.1 263345 D 512562 CDS YP_001909762.1 188527075 6296101 263630..264910 1 NC_010698.2 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 264910 6296101 HPSH_01400 Helicobacter pylori Shi470 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001909762.1 263630 D 512562 CDS YP_001909763.1 188527076 6296018 264950..265603 1 NC_010698.2 COG2121 Uncharacterized protein conserved in bacteria; hypothetical protein 265603 6296018 HPSH_01405 Helicobacter pylori Shi470 hypothetical protein YP_001909763.1 264950 D 512562 CDS YP_001909764.1 188527077 6296294 265596..266576 1 NC_010698.2 hypothetical protein 266576 6296294 HPSH_01410 Helicobacter pylori Shi470 hypothetical protein YP_001909764.1 265596 D 512562 CDS YP_001909765.1 188527078 6296300 266557..267099 1 NC_010698.2 hypothetical protein 267099 6296300 HPSH_01415 Helicobacter pylori Shi470 hypothetical protein YP_001909765.1 266557 D 512562 CDS YP_001909766.1 188527079 6296360 267096..267635 1 NC_010698.2 hypothetical protein 267635 6296360 HPSH_01420 Helicobacter pylori Shi470 hypothetical protein YP_001909766.1 267096 D 512562 CDS YP_001909767.1 188527080 6296926 267651..268049 1 NC_010698.2 COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 268049 6296926 HPSH_01425 Helicobacter pylori Shi470 hypothetical protein YP_001909767.1 267651 D 512562 CDS YP_001909768.1 188527081 6296202 268086..269378 1 NC_010698.2 COG0457 FOG: TPR repeat; ATP-dependent nuclease 269378 6296202 HPSH_01430 Helicobacter pylori Shi470 ATP-dependent nuclease YP_001909768.1 268086 D 512562 CDS YP_001909769.1 188527082 6296160 269366..269923 1 NC_010698.2 COG0134 Indole-3-glycerol phosphate synthase; hypothetical protein 269923 6296160 HPSH_01435 Helicobacter pylori Shi470 hypothetical protein YP_001909769.1 269366 D 512562 CDS YP_001909770.1 188527083 6296820 269980..270234 1 NC_010698.2 COG1145 Ferredoxin; ferredoxin 270234 6296820 HPSH_01440 Helicobacter pylori Shi470 ferredoxin YP_001909770.1 269980 D 512562 CDS YP_001909771.1 188527084 6296492 270244..271698 1 NC_010698.2 COG0248 Exopolyphosphatase; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase 271698 6296492 HPSH_01445 Helicobacter pylori Shi470 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase YP_001909771.1 270244 D 512562 CDS YP_001909772.1 188527085 6296961 271695..272705 1 NC_010698.2 COG0859 ADP-heptose:LPS heptosyltransferase; lipopolysaccharide heptosyltransferase-1 272705 6296961 HPSH_01450 Helicobacter pylori Shi470 lipopolysaccharide heptosyltransferase-1 YP_001909772.1 271695 D 512562 CDS YP_001909773.1 188527086 6296289 272702..273688 1 NC_010698.2 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 273688 6296289 HPSH_01455 Helicobacter pylori Shi470 lipid A biosynthesis lauroyl acyltransferase YP_001909773.1 272702 D 512562 CDS YP_001909774.1 188527087 6296585 complement(273744..274859) 1 NC_010698.2 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 274859 tgt 6296585 tgt Helicobacter pylori Shi470 queuine tRNA-ribosyltransferase YP_001909774.1 273744 R 512562 CDS YP_001909775.1 188527088 6296732 274916..276352 1 NC_010698.2 COG3400 Uncharacterized protein conserved in bacteria; hypothetical protein 276352 6296732 HPSH_01465 Helicobacter pylori Shi470 hypothetical protein YP_001909775.1 274916 D 512562 CDS YP_001909776.1 188527089 6297578 276357..277388 1 NC_010698.2 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 277388 aroB 6297578 aroB Helicobacter pylori Shi470 3-dehydroquinate synthase YP_001909776.1 276357 D 512562 CDS YP_001909777.1 188527090 6296874 277379..278944 1 NC_010698.2 COG0668 Small-conductance mechanosensitive channel; hypothetical protein 278944 6296874 HPSH_01475 Helicobacter pylori Shi470 hypothetical protein YP_001909777.1 277379 D 512562 CDS YP_001909778.1 188527091 6296393 278941..280197 1 NC_010698.2 COG0621 2-methylthioadenine synthetase; hypothetical protein 280197 6296393 HPSH_01480 Helicobacter pylori Shi470 hypothetical protein YP_001909778.1 278941 D 512562 CDS YP_001909779.1 188527092 6296522 280184..281836 1 NC_010698.2 COG0465 ATP-dependent Zn proteases; cell division protein FtsH 281836 6296522 HPSH_01485 Helicobacter pylori Shi470 cell division protein FtsH YP_001909779.1 280184 D 512562 CDS YP_001909780.1 188527093 6297160 281839..282357 1 NC_010698.2 hypothetical protein 282357 6297160 HPSH_01490 Helicobacter pylori Shi470 hypothetical protein YP_001909780.1 281839 D 512562 CDS YP_001909781.1 188527094 6296258 282370..282843 1 NC_010698.2 hypothetical protein 282843 6296258 HPSH_01495 Helicobacter pylori Shi470 hypothetical protein YP_001909781.1 282370 D 512562 CDS YP_001909782.1 188527095 6297010 282908..291607 1 NC_010698.2 toxin-like outer membrane protein 291607 6297010 HPSH_01500 Helicobacter pylori Shi470 toxin-like outer membrane protein YP_001909782.1 282908 D 512562 CDS YP_001909783.1 188527096 6296008 291655..292872 1 NC_010698.2 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 292872 6296008 HPSH_01505 Helicobacter pylori Shi470 diaminopimelate decarboxylase YP_001909783.1 291655 D 512562 CDS YP_001909784.1 188527097 6296351 292877..293167 1 NC_010698.2 COG1605 Chorismate mutase; hypothetical protein 293167 6296351 HPSH_01510 Helicobacter pylori Shi470 hypothetical protein YP_001909784.1 292877 D 512562 CDS YP_001909785.1 188527098 6296040 293180..294052 1 NC_010698.2 COG4866 Uncharacterized conserved protein; hypothetical protein 294052 6296040 HPSH_01515 Helicobacter pylori Shi470 hypothetical protein YP_001909785.1 293180 D 512562 CDS YP_001909786.1 188527099 6296368 294053..295732 1 NC_010698.2 COG0147 Anthranilate/para-aminobenzoate synthases component I; para-aminobenzoate synthetase PabB 295732 6296368 HPSH_01520 Helicobacter pylori Shi470 para-aminobenzoate synthetase PabB YP_001909786.1 294053 D 512562 CDS YP_001909787.1 188527100 6296610 295918..296937 1 NC_010698.2 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 296937 amiE 6296610 amiE Helicobacter pylori Shi470 acylamide amidohydrolase YP_001909787.1 295918 D 512562 CDS YP_001909788.1 188527101 6297374 complement(297020..299506) 1 NC_010698.2 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL 299506 flgL 6297374 flgL Helicobacter pylori Shi470 flagellar hook-associated protein FlgL YP_001909788.1 297020 R 512562 CDS YP_001909789.1 188527102 6296448 299726..300040 1 NC_010698.2 COG0261 Ribosomal protein L21; 50S ribosomal protein L21 300040 rplU 6296448 rplU Helicobacter pylori Shi470 50S ribosomal protein L21 YP_001909789.1 299726 D 512562 CDS YP_001909790.1 188527103 6296228 300055..300321 1 NC_010698.2 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 300321 rpmA 6296228 rpmA Helicobacter pylori Shi470 50S ribosomal protein L27 YP_001909790.1 300055 D 512562 CDS YP_001909791.1 188527104 6296401 300438..302087 1 NC_010698.2 COG0747 ABC-type dipeptide transport system, periplasmic component; periplasmic dipeptide-binding protein 302087 6296401 HPSH_01545 Helicobacter pylori Shi470 periplasmic dipeptide-binding protein YP_001909791.1 300438 D 512562 CDS YP_001909792.1 188527105 6296208 302098..303102 1 NC_010698.2 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide permease 303102 6296208 HPSH_01550 Helicobacter pylori Shi470 dipeptide permease YP_001909792.1 302098 D 512562 CDS YP_001909793.1 188527106 6296427 303102..303959 1 NC_010698.2 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide permease 303959 6296427 HPSH_01555 Helicobacter pylori Shi470 dipeptide permease YP_001909793.1 303102 D 512562 CDS YP_001909794.1 188527107 6296593 303971..304834 1 NC_010698.2 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; dipeptide ABC transporter ATP-binding protein DppD 304834 6296593 HPSH_01560 Helicobacter pylori Shi470 dipeptide ABC transporter ATP-binding protein DppD YP_001909794.1 303971 D 512562 CDS YP_001909795.1 188527108 6296546 304831..305637 1 NC_010698.2 COG4608 ABC-type oligopeptide transport system, ATPase component; dipeptide transport system atp-binding protein 305637 6296546 HPSH_01565 Helicobacter pylori Shi470 dipeptide transport system atp-binding protein YP_001909795.1 304831 D 512562 CDS YP_001909796.1 188527109 6296155 305657..306739 1 NC_010698.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 306739 obgE 6296155 obgE Helicobacter pylori Shi470 GTPase ObgE YP_001909796.1 305657 D 512562 CDS YP_001909797.1 188527110 6296501 306781..307776 1 NC_010698.2 hypothetical protein 307776 6296501 HPSH_01575 Helicobacter pylori Shi470 hypothetical protein YP_001909797.1 306781 D 512562 CDS YP_001909798.1 188527111 6296511 308024..308578 1 NC_010698.2 hypothetical protein 308578 6296511 HPSH_01580 Helicobacter pylori Shi470 hypothetical protein YP_001909798.1 308024 D 512562 CDS YP_001909799.1 188527112 6297135 308588..309880 1 NC_010698.2 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 309880 6297135 HPSH_01585 Helicobacter pylori Shi470 glutamate-1-semialdehyde aminotransferase YP_001909799.1 308588 D 512562 CDS YP_001909800.1 188527113 6296370 309885..310142 1 NC_010698.2 hypothetical protein 310142 6296370 HPSH_01590 Helicobacter pylori Shi470 hypothetical protein YP_001909800.1 309885 D 512562 CDS YP_001909801.1 188527114 6297108 310158..310562 1 NC_010698.2 hypothetical protein 310562 6297108 HPSH_01595 Helicobacter pylori Shi470 hypothetical protein YP_001909801.1 310158 D 512562 CDS YP_001909802.1 188527115 6296651 310646..311530 1 NC_010698.2 COG0388 Predicted amidohydrolase; hypothetical protein 311530 6296651 HPSH_01600 Helicobacter pylori Shi470 hypothetical protein YP_001909802.1 310646 D 512562 CDS YP_001909803.1 188527116 6296661 complement(312479..313171) 1 NC_010698.2 type II restriction enzyme 313171 6296661 HPSH_01615 Helicobacter pylori Shi470 type II restriction enzyme YP_001909803.1 312479 R 512562 CDS YP_001909804.1 188527117 6296381 complement(313182..314291) 1 NC_010698.2 COG0863 DNA modification methylase; DNA methylase 314291 6296381 HPSH_01620 Helicobacter pylori Shi470 DNA methylase YP_001909804.1 313182 R 512562 CDS YP_001909805.1 188527118 6297534 314387..314743 1 NC_010698.2 hypothetical protein 314743 6297534 HPSH_01625 Helicobacter pylori Shi470 hypothetical protein YP_001909805.1 314387 D 512562 CDS YP_001909806.1 188527119 6296281 314743..315705 1 NC_010698.2 COG0523 Putative GTPases (G3E family); ATP-binding protein 315705 6296281 HPSH_01630 Helicobacter pylori Shi470 ATP-binding protein YP_001909806.1 314743 D 512562 CDS YP_001909807.1 188527120 6296298 complement(315711..316856) 1 NC_010698.2 COG0477 Permeases of the major facilitator superfamily; nitrite extrusion protein NarK 316856 6296298 HPSH_01635 Helicobacter pylori Shi470 nitrite extrusion protein NarK YP_001909807.1 315711 R 512562 CDS YP_001909808.1 188527121 6296770 317180..317260 1 NC_010698.2 hypothetical protein 317260 6296770 HPSH_01640 Helicobacter pylori Shi470 hypothetical protein YP_001909808.1 317180 D 512562 CDS YP_001909809.1 188527122 6296347 complement(317346..318101) 1 NC_010698.2 COG0748 Putative heme iron utilization protein; hypothetical protein 318101 6296347 HPSH_01645 Helicobacter pylori Shi470 hypothetical protein YP_001909809.1 317346 R 512562 CDS YP_001909810.1 188527123 6296771 complement(318162..319787) 1 NC_010698.2 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 319787 argS 6296771 argS Helicobacter pylori Shi470 arginyl-tRNA synthetase YP_001909810.1 318162 R 512562 CDS YP_001909811.1 188527124 6296080 complement(319790..320029) 1 NC_010698.2 COG1826 Sec-independent protein secretion pathway components; sec-independent protein translocase protein 320029 6296080 HPSH_01655 Helicobacter pylori Shi470 sec-independent protein translocase protein YP_001909811.1 319790 R 512562 CDS YP_001909812.1 188527125 6296426 complement(320099..320719) 1 NC_010698.2 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 320719 gmk 6296426 gmk Helicobacter pylori Shi470 guanylate kinase YP_001909812.1 320099 R 512562 CDS YP_001909813.1 188527126 6297351 complement(320712..322187) 1 NC_010698.2 poly E-rich protein 322187 6297351 HPSH_01665 Helicobacter pylori Shi470 poly E-rich protein YP_001909813.1 320712 R 512562 CDS YP_001909814.1 188527127 6296489 complement(322200..322325) 1 NC_010698.2 hypothetical protein 322325 6296489 HPSH_01670 Helicobacter pylori Shi470 hypothetical protein YP_001909814.1 322200 R 512562 CDS YP_001909815.1 188527128 6297375 322329..322871 1 NC_010698.2 membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT 322871 6297375 HPSH_01675 Helicobacter pylori Shi470 nuclease NucT YP_001909815.1 322329 D 512562 CDS YP_001909816.1 188527129 6296505 complement(322878..323615) 1 NC_010698.2 outer membrane protein HorC 323615 6296505 HPSH_01680 Helicobacter pylori Shi470 outer membrane protein HorC YP_001909816.1 322878 R 512562 CDS YP_001909817.1 188527130 6296650 323745..324458 1 NC_010698.2 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 324458 flgH 6296650 flgH Helicobacter pylori Shi470 flagellar basal body L-ring protein YP_001909817.1 323745 D 512562 CDS YP_001909818.1 188527131 6296388 324476..325159 1 NC_010698.2 COG1083 CMP-N-acetylneuraminic acid synthetase; CMP-N-acetylneuraminic acid synthetase 325159 6296388 HPSH_01690 Helicobacter pylori Shi470 CMP-N-acetylneuraminic acid synthetase YP_001909818.1 324476 D 512562 CDS YP_001909819.1 188527132 6296210 325150..326022 1 NC_010698.2 COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase; CMP-N-acetylneuraminic acid synthetase NeuA 326022 6296210 HPSH_01695 Helicobacter pylori Shi470 CMP-N-acetylneuraminic acid synthetase NeuA YP_001909819.1 325150 D 512562 CDS YP_001909820.1 188527133 6296409 326019..326561 1 NC_010698.2 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; flagellar biosynthesis protein G 326561 6296409 HPSH_01700 Helicobacter pylori Shi470 flagellar biosynthesis protein G YP_001909820.1 326019 D 512562 CDS YP_001909821.1 188527134 6296250 complement(326494..327432) 1 NC_010698.2 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 327432 lpxK 6296250 lpxK Helicobacter pylori Shi470 tetraacyldisaccharide 4'-kinase YP_001909821.1 326494 R 512562 CDS YP_001909822.1 188527135 6296428 complement(327429..328211) 1 NC_010698.2 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 328211 6296428 HPSH_01710 Helicobacter pylori Shi470 NAD synthetase YP_001909822.1 327429 R 512562 CDS YP_001909823.1 188527136 6296305 328458..329450 1 NC_010698.2 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 329450 6296305 HPSH_01715 Helicobacter pylori Shi470 ketol-acid reductoisomerase YP_001909823.1 328458 D 512562 CDS YP_001909824.1 188527137 6297345 329469..330275 1 NC_010698.2 COG2894 Septum formation inhibitor-activating ATPase; cell division inhibitor MinD 330275 6297345 HPSH_01720 Helicobacter pylori Shi470 cell division inhibitor MinD YP_001909824.1 329469 D 512562 CDS YP_001909825.1 188527138 6296055 330272..330505 1 NC_010698.2 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 330505 minE 6296055 minE Helicobacter pylori Shi470 cell division topological specificity factor MinE YP_001909825.1 330272 D 512562 CDS YP_001909826.1 188527139 6296194 330517..331317 1 NC_010698.2 COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 331317 6296194 HPSH_01730 Helicobacter pylori Shi470 hypothetical protein YP_001909826.1 330517 D 512562 CDS YP_001909827.1 188527140 6296225 331314..331718 1 NC_010698.2 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 331718 6296225 HPSH_01735 Helicobacter pylori Shi470 Holliday junction resolvase-like protein YP_001909827.1 331314 D 512562 CDS YP_001909828.1 188527141 6297332 331775..331849 1 NC_010698.2 hypothetical protein 331849 6297332 HPSH_01740 Helicobacter pylori Shi470 hypothetical protein YP_001909828.1 331775 D 512562 CDS YP_001909829.1 188527142 6296536 331849..332319 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein H 332319 6296536 HPSH_01745 Helicobacter pylori Shi470 cysteine-rich protein H YP_001909829.1 331849 D 512562 CDS YP_001909830.1 188527143 6297316 332509..332847 1 NC_010698.2 hypothetical protein 332847 6297316 HPSH_01750 Helicobacter pylori Shi470 hypothetical protein YP_001909830.1 332509 D 512562 CDS YP_001909831.1 188527144 6296923 332831..333397 1 NC_010698.2 hypothetical protein 333397 6296923 HPSH_01755 Helicobacter pylori Shi470 hypothetical protein YP_001909831.1 332831 D 512562 CDS YP_001909832.1 188527145 6297100 333409..333657 1 NC_010698.2 hypothetical protein 333657 6297100 HPSH_01760 Helicobacter pylori Shi470 hypothetical protein YP_001909832.1 333409 D 512562 CDS YP_001909833.1 188527146 6297274 333663..334040 1 NC_010698.2 hypothetical protein 334040 6297274 HPSH_01765 Helicobacter pylori Shi470 hypothetical protein YP_001909833.1 333663 D 512562 CDS YP_001909834.1 188527147 6296112 334131..334250 1 NC_010698.2 hypothetical protein 334250 6296112 HPSH_01770 Helicobacter pylori Shi470 hypothetical protein YP_001909834.1 334131 D 512562 CDS YP_001909835.1 188527148 6296282 334247..334321 1 NC_010698.2 hypothetical protein 334321 6296282 HPSH_01775 Helicobacter pylori Shi470 hypothetical protein YP_001909835.1 334247 D 512562 CDS YP_001909836.1 188527149 6296944 334312..334773 1 NC_010698.2 COG3326 Predicted membrane protein; hypothetical protein 334773 6296944 HPSH_01780 Helicobacter pylori Shi470 hypothetical protein YP_001909836.1 334312 D 512562 CDS YP_001909837.1 188527150 6296345 334789..335574 1 NC_010698.2 hypothetical protein 335574 6296345 HPSH_01785 Helicobacter pylori Shi470 hypothetical protein YP_001909837.1 334789 D 512562 CDS YP_001909838.1 188527151 6296283 335564..336646 1 NC_010698.2 hypothetical protein 336646 6296283 HPSH_01790 Helicobacter pylori Shi470 hypothetical protein YP_001909838.1 335564 D 512562 CDS YP_001909839.1 188527152 6296006 complement(336702..337583) 1 NC_010698.2 COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein 337583 6296006 HPSH_01795 Helicobacter pylori Shi470 hypothetical protein YP_001909839.1 336702 R 512562 CDS YP_001909840.1 188527153 6296254 complement(337583..339133) 1 NC_010698.2 COG0608 Single-stranded DNA-specific exonuclease; single-stranded-DNA specific exonuclease 339133 6296254 HPSH_01800 Helicobacter pylori Shi470 single-stranded-DNA specific exonuclease YP_001909840.1 337583 R 512562 CDS YP_001909841.1 188527154 6296220 complement(339142..340758) 1 NC_010698.2 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 340758 pyrG 6296220 pyrG Helicobacter pylori Shi470 CTP synthetase YP_001909841.1 339142 R 512562 CDS YP_001909842.1 188527155 6296494 341014..341676 1 NC_010698.2 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 341676 6296494 HPSH_01810 Helicobacter pylori Shi470 hypothetical protein YP_001909842.1 341014 D 512562 CDS YP_001909843.1 188527156 6296045 341720..343423 1 NC_010698.2 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 343423 fliF 6296045 fliF Helicobacter pylori Shi470 flagellar MS-ring protein YP_001909843.1 341720 D 512562 CDS YP_001909844.1 188527157 6296100 343442..344473 1 NC_010698.2 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 344473 fliG 6296100 fliG Helicobacter pylori Shi470 flagellar motor switch protein G YP_001909844.1 343442 D 512562 CDS YP_001909845.1 188527158 6296186 344466..345236 1 NC_010698.2 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 345236 fliH 6296186 fliH Helicobacter pylori Shi470 flagellar assembly protein H YP_001909845.1 344466 D 512562 CDS YP_001909846.1 188527159 6296159 345239..347089 1 NC_010698.2 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 347089 6296159 HPSH_01830 Helicobacter pylori Shi470 1-deoxy-D-xylulose-5-phosphate synthase YP_001909846.1 345239 D 512562 CDS YP_001909847.1 188527160 6296204 347086..348894 1 NC_010698.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 348894 6296204 HPSH_01835 Helicobacter pylori Shi470 GTP-binding protein LepA YP_001909847.1 347086 D 512562 CDS YP_001909848.1 188527161 6297439 348903..349832 1 NC_010698.2 COG0270 Site-specific DNA methylase; DNA-cytosine methyltransferase 349832 6297439 HPSH_01840 Helicobacter pylori Shi470 DNA-cytosine methyltransferase YP_001909848.1 348903 D 512562 CDS YP_001909849.1 188527162 6296197 349825..350295 1 NC_010698.2 hypothetical protein 350295 6296197 HPSH_01845 Helicobacter pylori Shi470 hypothetical protein YP_001909849.1 349825 D 512562 CDS YP_001909850.1 188527163 6297254 complement(350770..351579) 1 NC_010698.2 COG4786 Flagellar basal body rod protein; flagellar basal-body rod protein FlgG 351579 6297254 HPSH_01850 Helicobacter pylori Shi470 flagellar basal-body rod protein FlgG YP_001909850.1 350770 R 512562 CDS YP_001909851.1 188527164 6296931 complement(351634..352920) 1 NC_010698.2 COG0477 Permeases of the major facilitator superfamily; alpha-ketoglutarate permease 352920 6296931 HPSH_01855 Helicobacter pylori Shi470 alpha-ketoglutarate permease YP_001909851.1 351634 R 512562 CDS YP_001909852.1 188527165 6297184 complement(353083..355722) 1 NC_010698.2 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division protein 355722 6297184 HPSH_01860 Helicobacter pylori Shi470 cell division protein YP_001909852.1 353083 R 512562 CDS YP_001909853.1 188527166 6296077 complement(355719..358055) 1 NC_010698.2 COG3893 Inactivated superfamily I helicase; hypothetical protein 358055 6296077 HPSH_01865 Helicobacter pylori Shi470 hypothetical protein YP_001909853.1 355719 R 512562 CDS YP_001909854.1 188527167 6296067 complement(358052..359977) 1 NC_010698.2 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 359977 6296067 HPSH_01870 Helicobacter pylori Shi470 transketolase YP_001909854.1 358052 R 512562 CDS YP_001909855.1 188527168 6297277 complement(360024..360866) 1 NC_010698.2 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 360866 6297277 HPSH_01875 Helicobacter pylori Shi470 bifunctional riboflavin kinase/FMN adenylyltransferase YP_001909855.1 360024 R 512562 CDS YP_001909856.1 188527169 6296023 complement(360832..361539) 1 NC_010698.2 COG1189 Predicted rRNA methylase; hemolysin 361539 6296023 HPSH_01880 Helicobacter pylori Shi470 hemolysin YP_001909856.1 360832 R 512562 CDS YP_001909857.1 188527170 6296286 complement(361539..362048) 1 NC_010698.2 hypothetical protein 362048 6296286 HPSH_01885 Helicobacter pylori Shi470 hypothetical protein YP_001909857.1 361539 R 512562 CDS YP_001909858.1 188527171 6296457 362121..363044 1 NC_010698.2 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 363044 pyrB 6296457 pyrB Helicobacter pylori Shi470 aspartate carbamoyltransferase catalytic subunit YP_001909858.1 362121 D 512562 CDS YP_001909859.1 188527172 6297297 complement(363054..363134) 1 NC_010698.2 hypothetical protein 363134 6297297 HPSH_01895 Helicobacter pylori Shi470 hypothetical protein YP_001909859.1 363054 R 512562 CDS YP_001909860.1 188527173 6296855 363339..364778 1 NC_010698.2 hypothetical protein 364778 6296855 HPSH_01900 Helicobacter pylori Shi470 hypothetical protein YP_001909860.1 363339 D 512562 CDS YP_001909861.1 188527174 6296013 364870..366525 1 NC_010698.2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein MsbA 366525 6296013 HPSH_01905 Helicobacter pylori Shi470 multidrug resistance protein MsbA YP_001909861.1 364870 D 512562 CDS YP_001909862.1 188527175 6296140 366519..367142 1 NC_010698.2 hypothetical protein 367142 6296140 HPSH_01910 Helicobacter pylori Shi470 hypothetical protein YP_001909862.1 366519 D 512562 CDS YP_001909863.1 188527176 6297206 367146..367715 1 NC_010698.2 COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes; hypothetical protein 367715 6297206 HPSH_01915 Helicobacter pylori Shi470 hypothetical protein YP_001909863.1 367146 D 512562 CDS YP_001909864.1 188527177 6296135 367826..369016 1 NC_010698.2 COG1106 Predicted ATPases; hypothetical protein 369016 6296135 HPSH_01920 Helicobacter pylori Shi470 hypothetical protein YP_001909864.1 367826 D 512562 CDS YP_001909865.1 188527178 6297028 369009..369671 1 NC_010698.2 hypothetical protein 369671 6297028 HPSH_01925 Helicobacter pylori Shi470 hypothetical protein YP_001909865.1 369009 D 512562 CDS YP_001909866.1 188527179 6296474 369752..370741 1 NC_010698.2 COG3376 High-affinity nickel permease; high affinity nickel transport protein 370741 6296474 HPSH_01930 Helicobacter pylori Shi470 high affinity nickel transport protein YP_001909866.1 369752 D 512562 CDS YP_001909867.1 188527180 6296026 complement(370745..371260) 1 NC_010698.2 hypothetical protein 371260 6296026 HPSH_01935 Helicobacter pylori Shi470 hypothetical protein YP_001909867.1 370745 R 512562 CDS YP_001909868.1 188527181 6296219 371393..372709 1 NC_010698.2 hypothetical protein 372709 6296219 HPSH_01940 Helicobacter pylori Shi470 hypothetical protein YP_001909868.1 371393 D 512562 CDS YP_001909869.1 188527182 6296114 373057..373194 1 NC_010698.2 hypothetical protein 373194 6296114 HPSH_01945 Helicobacter pylori Shi470 hypothetical protein YP_001909869.1 373057 D 512562 CDS YP_001909870.1 188527183 6297339 373184..373249 1 NC_010698.2 hypothetical protein 373249 6297339 HPSH_01950 Helicobacter pylori Shi470 hypothetical protein YP_001909870.1 373184 D 512562 CDS YP_001909871.1 188527184 6296497 373334..373462 1 NC_010698.2 hypothetical protein 373462 6296497 HPSH_01955 Helicobacter pylori Shi470 hypothetical protein YP_001909871.1 373334 D 512562 CDS YP_001909872.1 188527185 6296366 complement(373835..374038) 1 NC_010698.2 COG2608 Copper chaperone; copper ion binding protein CopP 374038 6296366 HPSH_01960 Helicobacter pylori Shi470 copper ion binding protein CopP YP_001909872.1 373835 R 512562 CDS YP_001909873.1 188527186 6296149 complement(374039..376264) 1 NC_010698.2 COG2217 Cation transport ATPase; copper-transporting ATPase 376264 6296149 HPSH_01965 Helicobacter pylori Shi470 copper-transporting ATPase YP_001909873.1 374039 R 512562 CDS YP_001909874.1 188527187 6296276 complement(376261..376974) 1 NC_010698.2 COG1183 Phosphatidylserine synthase; phosphatidylserine synthase 376974 6296276 HPSH_01970 Helicobacter pylori Shi470 phosphatidylserine synthase YP_001909874.1 376261 R 512562 CDS YP_001909875.1 188527188 6296110 complement(377220..379118) 1 NC_010698.2 COG0465 ATP-dependent Zn proteases; cell division protein FtsH 379118 6296110 HPSH_01975 Helicobacter pylori Shi470 cell division protein FtsH YP_001909875.1 377220 R 512562 CDS YP_001909876.1 188527189 6296162 complement(379127..380116) 1 NC_010698.2 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 380116 prmA 6296162 prmA Helicobacter pylori Shi470 ribosomal protein L11 methyltransferase YP_001909876.1 379127 R 512562 CDS YP_001909877.1 188527190 6296205 complement(380117..380491) 1 NC_010698.2 COG0784 FOG: CheY-like receiver; response regulator 380491 6296205 HPSH_01985 Helicobacter pylori Shi470 response regulator YP_001909877.1 380117 R 512562 CDS YP_001909878.1 188527191 6296446 380783..381385 1 NC_010698.2 outer membrane protein HorD 381385 6296446 HPSH_01990 Helicobacter pylori Shi470 outer membrane protein HorD YP_001909878.1 380783 D 512562 CDS YP_001909879.1 188527192 6296478 complement(381517..381924) 1 NC_010698.2 hypothetical protein 381924 6296478 HPSH_01995 Helicobacter pylori Shi470 hypothetical protein YP_001909879.1 381517 R 512562 CDS YP_001909880.1 188527193 6296048 complement(381927..382157) 1 NC_010698.2 hypothetical protein 382157 6296048 HPSH_02000 Helicobacter pylori Shi470 hypothetical protein YP_001909880.1 381927 R 512562 CDS YP_001909881.1 188527194 6296437 complement(382151..382687) 1 NC_010698.2 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 382687 gidB 6296437 gidB Helicobacter pylori Shi470 16S rRNA methyltransferase GidB YP_001909881.1 382151 R 512562 CDS YP_001909882.1 188527195 6296176 complement(382684..383721) 1 NC_010698.2 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 383721 queA 6296176 queA Helicobacter pylori Shi470 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_001909882.1 382684 R 512562 CDS YP_001909883.1 188527196 6297140 complement(383722..384483) 1 NC_010698.2 COG0805 Sec-independent protein secretion pathway component TatC; hypothetical protein 384483 6297140 HPSH_02015 Helicobacter pylori Shi470 hypothetical protein YP_001909883.1 383722 R 512562 CDS YP_001909884.1 188527197 6296917 complement(384476..384958) 1 NC_010698.2 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 384958 6296917 HPSH_02020 Helicobacter pylori Shi470 sec-independent translocase YP_001909884.1 384476 R 512562 CDS YP_001909885.1 188527198 6296241 complement(385026..386036) 1 NC_010698.2 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 386036 ruvB 6296241 ruvB Helicobacter pylori Shi470 Holliday junction DNA helicase RuvB YP_001909885.1 385026 R 512562 CDS YP_001909886.1 188527199 6296500 complement(386037..386849) 1 NC_010698.2 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 386849 panB 6296500 panB Helicobacter pylori Shi470 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001909886.1 386037 R 512562 CDS YP_001909887.1 188527200 6296198 386997..387719 1 NC_010698.2 hypothetical protein 387719 6296198 HPSH_02035 Helicobacter pylori Shi470 hypothetical protein YP_001909887.1 386997 D 512562 CDS YP_001909888.1 188527201 6296299 387709..388563 1 NC_010698.2 hypothetical protein 388563 6296299 HPSH_02040 Helicobacter pylori Shi470 hypothetical protein YP_001909888.1 387709 D 512562 CDS YP_001909889.1 188527202 6296233 388575..389516 1 NC_010698.2 hypothetical protein 389516 6296233 HPSH_02045 Helicobacter pylori Shi470 hypothetical protein YP_001909889.1 388575 D 512562 CDS YP_001909890.1 188527203 6296022 389526..390848 1 NC_010698.2 COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 390848 6296022 HPSH_02050 Helicobacter pylori Shi470 hypothetical protein YP_001909890.1 389526 D 512562 CDS YP_001909891.1 188527204 6296865 390851..391438 1 NC_010698.2 blocks the formation of polar Z-ring septums; septum formation inhibitor 391438 minC 6296865 minC Helicobacter pylori Shi470 septum formation inhibitor YP_001909891.1 390851 D 512562 CDS YP_001909892.1 188527205 6295992 391435..392322 1 NC_010698.2 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 392322 lpxC 6295992 lpxC Helicobacter pylori Shi470 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001909892.1 391435 D 512562 CDS YP_001909893.1 188527206 6296307 392343..392816 1 NC_010698.2 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; hypothetical protein 392816 6296307 HPSH_02065 Helicobacter pylori Shi470 hypothetical protein YP_001909893.1 392343 D 512562 CDS YP_001909894.1 188527207 6295993 392871..393752 1 NC_010698.2 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 393752 6295993 HPSH_02070 Helicobacter pylori Shi470 homoserine kinase YP_001909894.1 392871 D 512562 CDS YP_001909895.1 188527208 6297242 393739..393993 1 NC_010698.2 COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; hypothetical protein 393993 6297242 HPSH_02075 Helicobacter pylori Shi470 hypothetical protein YP_001909895.1 393739 D 512562 CDS YP_001909896.1 188527209 6296230 393990..396836 1 NC_010698.2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 396836 infB 6296230 infB Helicobacter pylori Shi470 translation initiation factor IF-2 YP_001909896.1 393990 D 512562 CDS YP_001909897.1 188527210 6296498 396836..397171 1 NC_010698.2 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 397171 rbfA 6296498 rbfA Helicobacter pylori Shi470 ribosome-binding factor A YP_001909897.1 396836 D 512562 CDS YP_001909898.1 188527211 6297264 397164..397604 1 NC_010698.2 COG0779 Uncharacterized protein conserved in bacteria; hypothetical protein 397604 6297264 HPSH_02090 Helicobacter pylori Shi470 hypothetical protein YP_001909898.1 397164 D 512562 CDS YP_001909899.1 188527212 6296293 397774..398886 1 NC_010698.2 COG1408 Predicted phosphohydrolases; hypothetical protein 398886 6296293 HPSH_02095 Helicobacter pylori Shi470 hypothetical protein YP_001909899.1 397774 D 512562 CDS YP_001909900.1 188527213 6296310 399227..399898 1 NC_010698.2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative transcriptional regulator 399898 6296310 HPSH_02100 Helicobacter pylori Shi470 putative transcriptional regulator YP_001909900.1 399227 D 512562 CDS YP_001909901.1 188527214 6296020 complement(400230..401276) 1 NC_010698.2 COG2404 Predicted phosphohydrolase (DHH superfamily); hypothetical protein 401276 6296020 HPSH_02105 Helicobacter pylori Shi470 hypothetical protein YP_001909901.1 400230 R 512562 CDS YP_001909902.1 188527215 6296424 complement(401304..403505) 1 NC_010698.2 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 403505 flhA 6296424 flhA Helicobacter pylori Shi470 flagellar biosynthesis protein FlhA YP_001909902.1 401304 R 512562 CDS YP_001909903.1 188527216 6296302 403643..403915 1 NC_010698.2 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 403915 rpsO 6296302 rpsO Helicobacter pylori Shi470 30S ribosomal protein S15 YP_001909903.1 403643 D 512562 CDS YP_001909904.1 188527217 6296214 403945..405234 1 NC_010698.2 COG3307 Lipid A core - O-antigen ligase and related enzymes; hypothetical protein 405234 6296214 HPSH_02120 Helicobacter pylori Shi470 hypothetical protein YP_001909904.1 403945 D 512562 CDS YP_001909905.1 188527218 6297164 405363..405866 1 NC_010698.2 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 405866 6297164 HPSH_02125 Helicobacter pylori Shi470 3-dehydroquinate dehydratase YP_001909905.1 405363 D 512562 CDS YP_001909906.1 188527219 6296146 405880..406953 1 NC_010698.2 COG0006 Xaa-Pro aminopeptidase; hypothetical protein 406953 6296146 HPSH_02130 Helicobacter pylori Shi470 hypothetical protein YP_001909906.1 405880 D 512562 CDS YP_001909907.1 188527220 6296969 406953..407441 1 NC_010698.2 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase FolK 407441 6296969 HPSH_02135 Helicobacter pylori Shi470 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase FolK YP_001909907.1 406953 D 512562 CDS YP_001909908.1 188527221 6296065 407435..408814 1 NC_010698.2 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 408814 flhF 6296065 flhF Helicobacter pylori Shi470 flagellar biosynthesis regulator FlhF YP_001909908.1 407435 D 512562 CDS YP_001909909.1 188527222 6296525 408811..409695 1 NC_010698.2 COG0455 ATPases involved in chromosome partitioning; ATP-binding protein 409695 6296525 HPSH_02145 Helicobacter pylori Shi470 ATP-binding protein YP_001909909.1 408811 D 512562 CDS YP_001909910.1 188527223 6297086 409700..410014 1 NC_010698.2 hypothetical protein 410014 6297086 HPSH_02150 Helicobacter pylori Shi470 hypothetical protein YP_001909910.1 409700 D 512562 CDS YP_001909911.1 188527224 6296129 410016..410768 1 NC_010698.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 410768 fliA 6296129 fliA Helicobacter pylori Shi470 flagellar biosynthesis sigma factor YP_001909911.1 410016 D 512562 CDS YP_001909912.1 188527225 6297087 410761..411825 1 NC_010698.2 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 411825 fliM 6297087 fliM Helicobacter pylori Shi470 flagellar motor switch protein FliM YP_001909912.1 410761 D 512562 CDS YP_001909913.1 188527226 6296295 411829..412695 1 NC_010698.2 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY 412695 6296295 HPSH_02165 Helicobacter pylori Shi470 flagellar motor switch protein FliY YP_001909913.1 411829 D 512562 CDS YP_001909914.1 188527227 6295996 412724..413260 1 NC_010698.2 COG2731 Beta-galactosidase, beta subunit; hypothetical protein 413260 6295996 HPSH_02170 Helicobacter pylori Shi470 hypothetical protein YP_001909914.1 412724 D 512562 CDS YP_001909915.1 188527228 6296499 413257..413757 1 NC_010698.2 COG4731 Uncharacterized protein conserved in bacteria; hypothetical protein 413757 6296499 HPSH_02175 Helicobacter pylori Shi470 hypothetical protein YP_001909915.1 413257 D 512562 CDS YP_001909916.1 188527229 6296971 complement(413777..414229) 1 NC_010698.2 COG0735 Fe2+/Zn2+ uptake regulation proteins; ferric uptake regulation protein 414229 6296971 HPSH_02180 Helicobacter pylori Shi470 ferric uptake regulation protein YP_001909916.1 413777 R 512562 CDS YP_001909917.1 188527230 6296209 complement(414389..415564) 1 NC_010698.2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA 415564 6296209 HPSH_02185 Helicobacter pylori Shi470 recombination factor protein RarA YP_001909917.1 414389 R 512562 CDS YP_001909918.1 188527231 6296935 complement(415561..415932) 1 NC_010698.2 COG0789 Predicted transcriptional regulators; putative heat shock protein HspR 415932 6296935 HPSH_02190 Helicobacter pylori Shi470 putative heat shock protein HspR YP_001909918.1 415561 R 512562 CDS YP_001909919.1 188527232 6296421 complement(415942..416808) 1 NC_010698.2 COG2214 DnaJ-class molecular chaperone; co-chaperone-curved DNA binding protein A 416808 6296421 HPSH_02195 Helicobacter pylori Shi470 co-chaperone-curved DNA binding protein A YP_001909919.1 415942 R 512562 CDS YP_001909920.1 188527233 6296455 416976..418226 1 NC_010698.2 hypothetical protein 418226 6296455 HPSH_02200 Helicobacter pylori Shi470 hypothetical protein YP_001909920.1 416976 D 512562 CDS YP_001909921.1 188527234 6296012 complement(418248..419024) 1 NC_010698.2 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); hypothetical protein 419024 6296012 HPSH_02205 Helicobacter pylori Shi470 hypothetical protein YP_001909921.1 418248 R 512562 CDS YP_001909922.1 188527235 6296165 complement(419350..420246) 1 NC_010698.2 COG0784 FOG: CheY-like receiver; response regulator 420246 6296165 HPSH_02210 Helicobacter pylori Shi470 response regulator YP_001909922.1 419350 R 512562 CDS YP_001909923.1 188527236 6296321 complement(420278..421498) 1 NC_010698.2 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein 421498 ispDF 6296321 ispDF Helicobacter pylori Shi470 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein YP_001909923.1 420278 R 512562 CDS YP_001909924.1 188527237 6296506 complement(421520..422950) 1 NC_010698.2 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; protease DO 422950 6296506 HPSH_02220 Helicobacter pylori Shi470 protease DO YP_001909924.1 421520 R 512562 CDS YP_001909925.1 188527238 6296044 complement(422995..424437) 1 NC_010698.2 COG0833 Amino acid transporters; amino acid permease 424437 6296044 HPSH_02225 Helicobacter pylori Shi470 amino acid permease YP_001909925.1 422995 R 512562 CDS YP_001909926.1 188527239 6296843 complement(424632..425171) 1 NC_010698.2 COG0558 Phosphatidylglycerophosphate synthase; phosphatidylglycerophosphate synthase 425171 6296843 HPSH_02230 Helicobacter pylori Shi470 phosphatidylglycerophosphate synthase YP_001909926.1 424632 R 512562 CDS YP_001909927.1 188527240 6296440 complement(425168..425776) 1 NC_010698.2 hypothetical protein 425776 6296440 HPSH_02235 Helicobacter pylori Shi470 hypothetical protein YP_001909927.1 425168 R 512562 CDS YP_001909928.1 188527241 6296845 complement(425786..426574) 1 NC_010698.2 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 426574 6296845 HPSH_02240 Helicobacter pylori Shi470 7-alpha-hydroxysteroid dehydrogenase YP_001909928.1 425786 R 512562 CDS YP_001909929.1 188527242 6296493 complement(426571..427473) 1 NC_010698.2 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 427473 6296493 HPSH_02245 Helicobacter pylori Shi470 dihydrodipicolinate synthase YP_001909929.1 426571 R 512562 CDS YP_001909930.1 188527243 6297271 complement(427488..428822) 1 NC_010698.2 COG0612 Predicted Zn-dependent peptidases; putative zinc protease 428822 6297271 HPSH_02250 Helicobacter pylori Shi470 putative zinc protease YP_001909930.1 427488 R 512562 CDS YP_001909931.1 188527244 6296003 complement(428819..429874) 1 NC_010698.2 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 429874 6296003 HPSH_02255 Helicobacter pylori Shi470 dihydroorotate dehydrogenase 2 YP_001909931.1 428819 R 512562 CDS YP_001909932.1 188527245 6296142 complement(429911..431938) 1 NC_010698.2 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 431938 6296142 HPSH_02260 Helicobacter pylori Shi470 polyphosphate kinase YP_001909932.1 429911 R 512562 CDS YP_001909933.1 188527246 6297068 complement(432577..433692) 1 NC_010698.2 COG0732 Restriction endonuclease S subunits; hypothetical protein 433692 6297068 HPSH_02265 Helicobacter pylori Shi470 hypothetical protein YP_001909933.1 432577 R 512562 CDS YP_001909934.1 188527247 6296509 complement(433685..435316) 1 NC_010698.2 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme M protein 435316 6296509 HPSH_02270 Helicobacter pylori Shi470 type I restriction enzyme M protein YP_001909934.1 433685 R 512562 CDS YP_001909935.1 188527248 6297155 complement(435309..438410) 1 NC_010698.2 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme R protein HsdR 438410 6297155 HPSH_02275 Helicobacter pylori Shi470 type I restriction enzyme R protein HsdR YP_001909935.1 435309 R 512562 CDS YP_001909936.1 188527249 6296074 complement(438458..440353) 1 NC_010698.2 COG2604 Uncharacterized protein conserved in bacteria; hypothetical protein 440353 6296074 HPSH_02280 Helicobacter pylori Shi470 hypothetical protein YP_001909936.1 438458 R 512562 CDS YP_001909937.1 188527250 6296568 complement(440379..441146) 1 NC_010698.2 hypothetical protein 441146 6296568 HPSH_02285 Helicobacter pylori Shi470 hypothetical protein YP_001909937.1 440379 R 512562 CDS YP_001909938.1 188527251 6296532 complement(441156..441470) 1 NC_010698.2 hypothetical protein 441470 6296532 HPSH_02290 Helicobacter pylori Shi470 hypothetical protein YP_001909938.1 441156 R 512562 CDS YP_001909939.1 188527252 6296469 complement(441472..442959) 1 NC_010698.2 COG2048 Heterodisulfide reductase, subunit B; hypothetical protein 442959 6296469 HPSH_02295 Helicobacter pylori Shi470 hypothetical protein YP_001909939.1 441472 R 512562 CDS YP_001909940.1 188527253 6296444 complement(442971..443459) 1 NC_010698.2 hypothetical protein 443459 6296444 HPSH_02300 Helicobacter pylori Shi470 hypothetical protein YP_001909940.1 442971 R 512562 CDS YP_001909941.1 188527254 6296237 complement(443444..445180) 1 NC_010698.2 COG1164 Oligoendopeptidase F; oligoendopeptidase F PepF 445180 6296237 HPSH_02305 Helicobacter pylori Shi470 oligoendopeptidase F PepF YP_001909941.1 443444 R 512562 CDS YP_001909942.1 188527255 6296260 complement(445277..446527) 1 NC_010698.2 COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein KefB 446527 6296260 HPSH_02310 Helicobacter pylori Shi470 glutathione-regulated potassium-efflux system protein KefB YP_001909942.1 445277 R 512562 CDS YP_001909943.1 188527256 6296090 complement(446680..446871) 1 NC_010698.2 hypothetical protein 446871 6296090 HPSH_02315 Helicobacter pylori Shi470 hypothetical protein YP_001909943.1 446680 R 512562 CDS YP_001909944.1 188527257 6297370 complement(446855..447415) 1 NC_010698.2 outer membrane protein 447415 6297370 HPSH_02320 Helicobacter pylori Shi470 outer membrane protein YP_001909944.1 446855 R 512562 CDS YP_001909945.1 188527258 6296043 complement(447459..447611) 1 NC_010698.2 hypothetical protein 447611 6296043 HPSH_02325 Helicobacter pylori Shi470 hypothetical protein YP_001909945.1 447459 R 512562 CDS YP_001909946.1 188527259 6296485 447639..448379 1 NC_010698.2 COG0725 ABC-type molybdate transport system, periplasmic component; molybdenum ABC transporter ModA 448379 6296485 HPSH_02330 Helicobacter pylori Shi470 molybdenum ABC transporter ModA YP_001909946.1 447639 D 512562 CDS YP_001909947.1 188527260 6297236 448401..449075 1 NC_010698.2 COG4149 ABC-type molybdate transport system, permease component; molybdenum ABC transporter ModB 449075 6297236 HPSH_02335 Helicobacter pylori Shi470 molybdenum ABC transporter ModB YP_001909947.1 448401 D 512562 CDS YP_001909948.1 188527261 6296117 449072..449869 1 NC_010698.2 COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; molybdenum ABC transporter ModD 449869 6296117 HPSH_02340 Helicobacter pylori Shi470 molybdenum ABC transporter ModD YP_001909948.1 449072 D 512562 CDS YP_001909949.1 188527262 6296962 complement(449951..451342) 1 NC_010698.2 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 451342 gltX 6296962 gltX Helicobacter pylori Shi470 glutamyl-tRNA synthetase YP_001909949.1 449951 R 512562 CDS YP_001909950.1 188527263 6297216 451461..452564 1 NC_010698.2 outer membrane protein 452564 6297216 HPSH_02350 Helicobacter pylori Shi470 outer membrane protein YP_001909950.1 451461 D 512562 CDS YP_001909951.1 188527264 6296119 452573..455023 1 NC_010698.2 COG0286 Type I restriction-modification system methyltransferase subunit; type II adenine specific methyltransferase 455023 6296119 HPSH_02355 Helicobacter pylori Shi470 type II adenine specific methyltransferase YP_001909951.1 452573 D 512562 CDS YP_001909952.1 188527265 6296108 455069..456868 1 NC_010698.2 COG1217 Predicted membrane GTPase involved in stress response; hypothetical protein 456868 6296108 HPSH_02360 Helicobacter pylori Shi470 hypothetical protein YP_001909952.1 455069 D 512562 CDS YP_001909953.1 188527266 6296454 456884..457813 1 NC_010698.2 COG0338 Site-specific DNA methylase; type II adenine specific DNA methyltransferase 457813 6296454 HPSH_02365 Helicobacter pylori Shi470 type II adenine specific DNA methyltransferase YP_001909953.1 456884 D 512562 CDS YP_001909954.1 188527267 6296070 457816..458439 1 NC_010698.2 type II restriction endonuclease 458439 6296070 HPSH_02370 Helicobacter pylori Shi470 type II restriction endonuclease YP_001909954.1 457816 D 512562 CDS YP_001909955.1 188527268 6296502 458530..459576 1 NC_010698.2 COG0270 Site-specific DNA methylase; type II DNA modification methyltransferase 459576 6296502 HPSH_02375 Helicobacter pylori Shi470 type II DNA modification methyltransferase YP_001909955.1 458530 D 512562 CDS YP_001909956.1 188527269 6296124 459579..459842 1 NC_010698.2 hypothetical protein 459842 6296124 HPSH_02380 Helicobacter pylori Shi470 hypothetical protein YP_001909956.1 459579 D 512562 CDS YP_001909957.1 188527270 6296508 459889..460326 1 NC_010698.2 hypothetical protein 460326 6296508 HPSH_02385 Helicobacter pylori Shi470 hypothetical protein YP_001909957.1 459889 D 512562 CDS YP_001909958.1 188527271 6296482 complement(460342..460509) 1 NC_010698.2 hypothetical protein 460509 6296482 HPSH_02390 Helicobacter pylori Shi470 hypothetical protein YP_001909958.1 460342 R 512562 CDS YP_001909959.1 188527272 6297308 complement(460559..461503) 1 NC_010698.2 COG0753 Catalase; catalase-like protein 461503 6297308 HPSH_02395 Helicobacter pylori Shi470 catalase-like protein YP_001909959.1 460559 R 512562 CDS YP_001909960.1 188527273 6296157 461787..463373 1 NC_010698.2 outer membrane protein HofC 463373 6296157 HPSH_02400 Helicobacter pylori Shi470 outer membrane protein HofC YP_001909960.1 461787 D 512562 CDS YP_001909961.1 188527274 6296334 463443..464840 1 NC_010698.2 putative Outer membrane protein 464840 6296334 HPSH_02405 Helicobacter pylori Shi470 putative Outer membrane protein YP_001909961.1 463443 D 512562 CDS YP_001909962.1 188527275 6296061 complement(465292..465498) 1 NC_010698.2 hypothetical protein 465498 6296061 HPSH_02410 Helicobacter pylori Shi470 hypothetical protein YP_001909962.1 465292 R 512562 CDS YP_001909963.1 188527276 6296007 465596..466195 1 NC_010698.2 hypothetical protein 466195 6296007 HPSH_02415 Helicobacter pylori Shi470 hypothetical protein YP_001909963.1 465596 D 512562 CDS YP_001909964.1 188527277 6297088 complement(466552..467277) 1 NC_010698.2 COG1432 Uncharacterized conserved protein; hypothetical protein 467277 6297088 HPSH_02420 Helicobacter pylori Shi470 hypothetical protein YP_001909964.1 466552 R 512562 CDS YP_001909965.1 188527278 6296551 467410..467883 1 NC_010698.2 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 467883 ruvC 6296551 ruvC Helicobacter pylori Shi470 Holliday junction resolvase YP_001909965.1 467410 D 512562 CDS YP_001909966.1 188527279 6296410 complement(467884..470259) 1 NC_010698.2 COG1629 Outer membrane receptor proteins, mostly Fe transport; iron-regulated outer membrane protein FrpB 470259 6296410 HPSH_02430 Helicobacter pylori Shi470 iron-regulated outer membrane protein FrpB YP_001909966.1 467884 R 512562 CDS YP_001909967.1 188527280 6297260 470584..472110 1 NC_010698.2 COG0753 Catalase; catalase 472110 6297260 HPSH_02435 Helicobacter pylori Shi470 catalase YP_001909967.1 470584 D 512562 CDS YP_001909968.1 188527281 6296094 472261..473136 1 NC_010698.2 hypothetical protein 473136 6296094 HPSH_02440 Helicobacter pylori Shi470 hypothetical protein YP_001909968.1 472261 D 512562 CDS YP_001909969.1 188527282 6296151 473217..473432 1 NC_010698.2 hypothetical protein 473432 6296151 HPSH_02445 Helicobacter pylori Shi470 hypothetical protein YP_001909969.1 473217 D 512562 CDS YP_001909970.1 188527283 6296395 complement(473490..473819) 1 NC_010698.2 COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; alkylphosphonate uptake protein 473819 6296395 HPSH_02450 Helicobacter pylori Shi470 alkylphosphonate uptake protein YP_001909970.1 473490 R 512562 CDS YP_001909971.1 188527284 6296468 474171..474905 1 NC_010698.2 COG2134 CDP-diacylglycerol pyrophosphatase; CDP-diacylglycerol pyrophosphatase 474905 6296468 HPSH_02455 Helicobacter pylori Shi470 CDP-diacylglycerol pyrophosphatase YP_001909971.1 474171 D 512562 CDS YP_001909972.1 188527285 6296322 475109..477265 1 NC_010698.2 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 477265 flgE 6296322 flgE Helicobacter pylori Shi470 flagellar hook protein FlgE YP_001909972.1 475109 D 512562 CDS YP_001909973.1 188527286 6297149 477323..477676 1 NC_010698.2 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 477676 hypA 6297149 hypA Helicobacter pylori Shi470 hydrogenase nickel incorporation protein YP_001909973.1 477323 D 512562 CDS YP_001909974.1 188527287 6296435 477683..478144 1 NC_010698.2 hypothetical protein 478144 6296435 HPSH_02470 Helicobacter pylori Shi470 hypothetical protein YP_001909974.1 477683 D 512562 CDS YP_001909975.1 188527288 6297083 478144..479226 1 NC_010698.2 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase 479226 lpxB 6297083 lpxB Helicobacter pylori Shi470 ipid-A-disaccharide synthase YP_001909975.1 478144 D 512562 CDS YP_001909976.1 188527289 6296519 479267..479761 1 NC_010698.2 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 479761 greA 6296519 greA Helicobacter pylori Shi470 transcription elongation factor GreA YP_001909976.1 479267 D 512562 CDS YP_001909977.1 188527290 6296438 479751..480188 1 NC_010698.2 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 480188 dut 6296438 dut Helicobacter pylori Shi470 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001909977.1 479751 D 512562 CDS YP_001909978.1 188527291 6296361 480185..480841 1 NC_010698.2 hypothetical protein 480841 6296361 HPSH_02490 Helicobacter pylori Shi470 hypothetical protein YP_001909978.1 480185 D 512562 CDS YP_001909979.1 188527292 6296471 480846..482540 1 NC_010698.2 hypothetical protein 482540 6296471 HPSH_02495 Helicobacter pylori Shi470 hypothetical protein YP_001909979.1 480846 D 512562 CDS YP_001909980.1 188527293 6297230 482545..483216 1 NC_010698.2 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 483216 6297230 HPSH_02500 Helicobacter pylori Shi470 pantothenate kinase YP_001909980.1 482545 D 512562 CDS YP_001909981.1 188527294 6297163 483207..483944 1 NC_010698.2 COG2836 Uncharacterized conserved protein; hypothetical protein 483944 6297163 HPSH_02505 Helicobacter pylori Shi470 hypothetical protein YP_001909981.1 483207 D 512562 CDS YP_001909982.1 188527295 6296529 483931..484455 1 NC_010698.2 COG0241 Histidinol phosphatase and related phosphatases; hypothetical protein 484455 6296529 HPSH_02510 Helicobacter pylori Shi470 hypothetical protein YP_001909982.1 483931 D 512562 CDS YP_001909983.1 188527296 6297263 484464..485456 1 NC_010698.2 COG0451 Nucleoside-diphosphate-sugar epimerases; ADP-L-glycero-D-mannoheptose-6-epimerase RfaD 485456 6297263 HPSH_02515 Helicobacter pylori Shi470 ADP-L-glycero-D-mannoheptose-6-epimerase RfaD YP_001909983.1 484464 D 512562 CDS YP_001909984.1 188527297 6296123 485453..486844 1 NC_010698.2 COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; ADP-heptose synthase 486844 6296123 HPSH_02520 Helicobacter pylori Shi470 ADP-heptose synthase YP_001909984.1 485453 D 512562 CDS YP_001909985.1 188527298 6296378 486837..487415 1 NC_010698.2 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 487415 6296378 HPSH_02525 Helicobacter pylori Shi470 phosphoheptose isomerase YP_001909985.1 486837 D 512562 CDS YP_001909986.1 188527299 6296520 complement(487592..488569) 1 NC_010698.2 COG0516 IMP dehydrogenase/GMP reductase; guanosine 5'-monophosphate oxidoreductase 488569 6296520 HPSH_02530 Helicobacter pylori Shi470 guanosine 5'-monophosphate oxidoreductase YP_001909986.1 487592 R 512562 CDS YP_001909987.1 188527300 6296245 488818..490419 1 NC_010698.2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 490419 6296245 HPSH_02535 Helicobacter pylori Shi470 ABC transporter ATP-binding protein YP_001909987.1 488818 D 512562 CDS YP_001909988.1 188527301 6295997 490416..491333 1 NC_010698.2 COG2958 Uncharacterized protein conserved in bacteria; hypothetical protein 491333 6295997 HPSH_02540 Helicobacter pylori Shi470 hypothetical protein YP_001909988.1 490416 D 512562 CDS YP_001909989.1 188527302 6297124 complement(491371..492048) 1 NC_010698.2 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 492048 6297124 HPSH_02545 Helicobacter pylori Shi470 hypothetical protein YP_001909989.1 491371 R 512562 CDS YP_001909990.1 188527303 6296417 complement(492215..493168) 1 NC_010698.2 type II restriction endonuclease 493168 6296417 HPSH_02550 Helicobacter pylori Shi470 type II restriction endonuclease YP_001909990.1 492215 R 512562 CDS YP_001909991.1 188527304 6296441 complement(493165..494148) 1 NC_010698.2 COG0270 Site-specific DNA methylase; site-specific DNA methyltransferase 494148 6296441 HPSH_02555 Helicobacter pylori Shi470 site-specific DNA methyltransferase YP_001909991.1 493165 R 512562 CDS YP_001909992.1 188527305 6296001 494332..495921 1 NC_010698.2 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme M protein HsdM 495921 6296001 HPSH_02560 Helicobacter pylori Shi470 type I restriction enzyme M protein HsdM YP_001909992.1 494332 D 512562 CDS YP_001909993.1 188527306 6296042 495914..497182 1 NC_010698.2 COG0732 Restriction endonuclease S subunits; anti-codon nuclease masking agent PrrB 497182 6296042 HPSH_02565 Helicobacter pylori Shi470 anti-codon nuclease masking agent PrrB YP_001909993.1 495914 D 512562 CDS YP_001909994.1 188527307 6297384 497186..500185 1 NC_010698.2 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme R protein 500185 6297384 HPSH_02570 Helicobacter pylori Shi470 type I restriction enzyme R protein YP_001909994.1 497186 D 512562 CDS YP_001909995.1 188527308 6296306 500272..501051 1 NC_010698.2 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 501051 6296306 HPSH_02575 Helicobacter pylori Shi470 hydroxyethylthiazole kinase YP_001909995.1 500272 D 512562 CDS YP_001909996.1 188527309 6296172 501048..501857 1 NC_010698.2 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; thiamine biosynthesis protein (thi) 501857 6296172 HPSH_02580 Helicobacter pylori Shi470 thiamine biosynthesis protein (thi) YP_001909996.1 501048 D 512562 CDS YP_001909997.1 188527310 6296133 501850..502509 1 NC_010698.2 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 502509 thiE 6296133 thiE Helicobacter pylori Shi470 thiamine-phosphate pyrophosphorylase YP_001909997.1 501850 D 512562 CDS YP_001909998.1 188527311 6296535 complement(502564..503301) 1 NC_010698.2 hypothetical protein 503301 6296535 HPSH_02590 Helicobacter pylori Shi470 hypothetical protein YP_001909998.1 502564 R 512562 CDS YP_001909999.1 188527312 6296263 complement(503301..504578) 1 NC_010698.2 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 504578 6296263 HPSH_02595 Helicobacter pylori Shi470 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001909999.1 503301 R 512562 CDS YP_001910000.1 188527313 6296148 complement(504575..505558) 1 NC_010698.2 COG1086 Predicted nucleoside-diphosphate sugar epimerases; UDP-GlcNAc C6 dehydratase 505558 6296148 HPSH_02600 Helicobacter pylori Shi470 UDP-GlcNAc C6 dehydratase YP_001910000.1 504575 R 512562 CDS YP_001910001.1 188527314 6296333 complement(505562..507325) 1 NC_010698.2 COG2067 Long-chain fatty acid transport protein; outer membrane protein P1 507325 6296333 HPSH_02605 Helicobacter pylori Shi470 outer membrane protein P1 YP_001910001.1 505562 R 512562 CDS YP_001910002.1 188527315 6296304 complement(507322..507939) 1 NC_010698.2 hypothetical protein 507939 6296304 HPSH_02610 Helicobacter pylori Shi470 hypothetical protein YP_001910002.1 507322 R 512562 CDS YP_001910003.1 188527316 6296190 complement(507958..508563) 1 NC_010698.2 COG3018 Uncharacterized protein conserved in bacteria; hypothetical protein 508563 6296190 HPSH_02615 Helicobacter pylori Shi470 hypothetical protein YP_001910003.1 507958 R 512562 CDS YP_001910004.1 188527317 6296540 complement(508903..509007) 1 NC_010698.2 hypothetical protein 509007 6296540 HPSH_02620 Helicobacter pylori Shi470 hypothetical protein YP_001910004.1 508903 R 512562 CDS YP_001910005.1 188527318 6296262 complement(509236..509520) 1 NC_010698.2 COG0776 Bacterial nucleoid DNA-binding protein; dna-binding protein hu 509520 6296262 HPSH_02625 Helicobacter pylori Shi470 dna-binding protein hu YP_001910005.1 509236 R 512562 CDS YP_001910006.1 188527319 6296121 complement(509662..511047) 1 NC_010698.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 511047 engA 6296121 engA Helicobacter pylori Shi470 GTP-binding protein EngA YP_001910006.1 509662 R 512562 CDS YP_001910007.1 188527320 6296379 511124..512008 1 NC_010698.2 hypothetical protein 512008 6296379 HPSH_02635 Helicobacter pylori Shi470 hypothetical protein YP_001910007.1 511124 D 512562 CDS YP_001910008.1 188527321 6297071 512093..512881 1 NC_010698.2 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 512881 speE 6297071 speE Helicobacter pylori Shi470 spermidine synthase YP_001910008.1 512093 D 512562 CDS YP_001910009.1 188527322 6296383 512883..513473 1 NC_010698.2 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 513473 coaE 6296383 coaE Helicobacter pylori Shi470 dephospho-CoA kinase YP_001910009.1 512883 D 512562 CDS YP_001910010.1 188527323 6296192 513532..514893 1 NC_010698.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 514893 gatA 6296192 gatA Helicobacter pylori Shi470 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001910010.1 513532 D 512562 CDS YP_001910011.1 188527324 6296264 514903..516348 1 NC_010698.2 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 516348 6296264 HPSH_02655 Helicobacter pylori Shi470 inosine 5'-monophosphate dehydrogenase YP_001910011.1 514903 D 512562 CDS YP_001910012.1 188527325 6296134 516470..517150 1 NC_010698.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 517150 6296134 HPSH_02660 Helicobacter pylori Shi470 F0F1 ATP synthase subunit A YP_001910012.1 516470 D 512562 CDS YP_001910013.1 188527326 6296126 complement(517147..517242) 1 NC_010698.2 hypothetical protein 517242 6296126 HPSH_02665 Helicobacter pylori Shi470 hypothetical protein YP_001910013.1 517147 R 512562 CDS YP_001910014.1 188527327 6297037 517470..517718 1 NC_010698.2 COG0724 RNA-binding proteins (RRM domain); RNA binding protein 517718 6297037 HPSH_02670 Helicobacter pylori Shi470 RNA binding protein YP_001910014.1 517470 D 512562 CDS YP_001910015.1 188527328 6296052 complement(517921..518742) 1 NC_010698.2 COG3306 Glycosyltransferase involved in LPS biosynthesis; lipooligosaccharide 5G8 epitope biosynthesis-associated protein 518742 6296052 HPSH_02675 Helicobacter pylori Shi470 lipooligosaccharide 5G8 epitope biosynthesis-associated protein YP_001910015.1 517921 R 512562 CDS YP_001910016.1 188527329 6296238 complement(518909..519844) 1 NC_010698.2 COG0492 Thioredoxin reductase; thioredoxin reductase 519844 6296238 HPSH_02680 Helicobacter pylori Shi470 thioredoxin reductase YP_001910016.1 518909 R 512562 CDS YP_001910017.1 188527330 6296252 complement(519850..520170) 1 NC_010698.2 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 520170 6296252 HPSH_02685 Helicobacter pylori Shi470 thioredoxin YP_001910017.1 519850 R 512562 CDS YP_001910018.1 188527331 6296464 complement(520259..520603) 1 NC_010698.2 COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein 520603 6296464 HPSH_02690 Helicobacter pylori Shi470 hypothetical protein YP_001910018.1 520259 R 512562 CDS YP_001910019.1 188527332 6297111 complement(520604..521869) 1 NC_010698.2 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 521869 6297111 HPSH_02695 Helicobacter pylori Shi470 homoserine dehydrogenase YP_001910019.1 520604 R 512562 CDS YP_001910020.1 188527333 6296224 complement(521880..523664) 1 NC_010698.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 523664 uvrC 6296224 uvrC Helicobacter pylori Shi470 excinuclease ABC subunit C YP_001910020.1 521880 R 512562 CDS YP_001910021.1 188527334 6296419 complement(523665..524126) 1 NC_010698.2 hypothetical protein 524126 6296419 HPSH_02705 Helicobacter pylori Shi470 hypothetical protein YP_001910021.1 523665 R 512562 CDS YP_001910022.1 188527335 6296348 524118..524297 1 NC_010698.2 hypothetical protein 524297 6296348 HPSH_02710 Helicobacter pylori Shi470 hypothetical protein YP_001910022.1 524118 D 512562 CDS YP_001910023.1 188527336 6296458 complement(524309..524950) 1 NC_010698.2 COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; osmoprotection protein ProV 524950 6296458 HPSH_02715 Helicobacter pylori Shi470 osmoprotection protein ProV YP_001910023.1 524309 R 512562 CDS YP_001910024.1 188527337 6296068 complement(524952..526613) 1 NC_010698.2 COG1174 ABC-type proline/glycine betaine transport systems, permease component; osmoprotection protein ProWX 526613 6296068 HPSH_02720 Helicobacter pylori Shi470 osmoprotection protein ProWX YP_001910024.1 524952 R 512562 CDS YP_001910025.1 188527338 6296496 complement(526793..527230) 1 NC_010698.2 hypothetical protein 527230 6296496 HPSH_02725 Helicobacter pylori Shi470 hypothetical protein YP_001910025.1 526793 R 512562 CDS YP_001910026.1 188527339 6296846 complement(527234..528001) 1 NC_010698.2 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 528001 motB 6296846 motB Helicobacter pylori Shi470 flagellar motor protein MotB YP_001910026.1 527234 R 512562 CDS YP_001910027.1 188527340 6296177 complement(528004..528777) 1 NC_010698.2 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 528777 6296177 HPSH_02735 Helicobacter pylori Shi470 flagellar motor protein MotA YP_001910027.1 528004 R 512562 CDS YP_001910028.1 188527341 6296418 complement(528793..529560) 1 NC_010698.2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; thiamin biosynthesis protein ThiF 529560 6296418 HPSH_02740 Helicobacter pylori Shi470 thiamin biosynthesis protein ThiF YP_001910028.1 528793 R 512562 CDS YP_001910029.1 188527342 6296512 complement(529561..530178) 1 NC_010698.2 COG0491 Zn-dependent hydrolases, including glyoxylases; hypothetical protein 530178 6296512 HPSH_02745 Helicobacter pylori Shi470 hypothetical protein YP_001910029.1 529561 R 512562 CDS YP_001910030.1 188527343 6296027 530311..531321 1 NC_010698.2 COG1565 Uncharacterized conserved protein; hypothetical protein 531321 6296027 HPSH_02750 Helicobacter pylori Shi470 hypothetical protein YP_001910030.1 530311 D 512562 CDS YP_001910031.1 188527344 6297057 531511..531630 1 NC_010698.2 hypothetical protein 531630 6297057 HPSH_02755 Helicobacter pylori Shi470 hypothetical protein YP_001910031.1 531511 D 512562 CDS YP_001910032.1 188527345 6296382 531690..532082 1 NC_010698.2 hypothetical protein 532082 6296382 HPSH_02760 Helicobacter pylori Shi470 hypothetical protein YP_001910032.1 531690 D 512562 CDS YP_001910033.1 188527346 6296396 532124..532663 1 NC_010698.2 COG0742 N6-adenine-specific methylase; N-6 adenine methyltransferase 532663 6296396 HPSH_02765 Helicobacter pylori Shi470 N-6 adenine methyltransferase YP_001910033.1 532124 D 512562 CDS YP_001910034.1 188527347 6297307 532672..533223 1 NC_010698.2 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 533223 fliL 6297307 fliL Helicobacter pylori Shi470 flagellar basal body-associated protein FliL YP_001910034.1 532672 D 512562 CDS YP_001910035.1 188527348 6296337 533290..533586 1 NC_010698.2 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 533586 acpS 6296337 acpS Helicobacter pylori Shi470 4'-phosphopantetheinyl transferase YP_001910035.1 533290 D 512562 CDS YP_001910036.1 188527349 6296248 533692..533826 1 NC_010698.2 iron(III dicitrate transport protein FecA 533826 6296248 HPSH_02780 Helicobacter pylori Shi470 iron(III dicitrate transport protein FecA YP_001910036.1 533692 D 512562 CDS YP_001910037.1 188527350 6296103 complement(533830..534450) 1 NC_010698.2 COG1451 Predicted metal-dependent hydrolase; hypothetical protein 534450 6296103 HPSH_02785 Helicobacter pylori Shi470 hypothetical protein YP_001910037.1 533830 R 512562 CDS YP_001910038.1 188527351 6296024 534532..535368 1 NC_010698.2 COG3306 Glycosyltransferase involved in LPS biosynthesis; putative lipopolysaccharide biosynthesis protein 535368 6296024 HPSH_02790 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001910038.1 534532 D 512562 CDS YP_001910039.1 188527352 6296034 535451..536485 1 NC_010698.2 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 536485 6296034 HPSH_02795 Helicobacter pylori Shi470 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein YP_001910039.1 535451 D 512562 CDS YP_001910040.1 188527353 6296959 536665..537411 1 NC_010698.2 hypothetical protein 537411 6296959 HPSH_02800 Helicobacter pylori Shi470 hypothetical protein YP_001910040.1 536665 D 512562 CDS YP_001910041.1 188527354 6296004 537530..538108 1 NC_010698.2 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 538108 ribA 6296004 ribA Helicobacter pylori Shi470 GTP cyclohydrolase II YP_001910041.1 537530 D 512562 CDS YP_001910042.1 188527355 6297117 538182..538403 1 NC_010698.2 COG1977 Molybdopterin converting factor, small subunit; molybdopterin converting factor subunit 1 MoaD 538403 6297117 HPSH_02810 Helicobacter pylori Shi470 molybdopterin converting factor subunit 1 MoaD YP_001910042.1 538182 D 512562 CDS YP_001910043.1 188527356 6296085 538404..538841 1 NC_010698.2 COG0314 Molybdopterin converting factor, large subunit; molybdopterin converting factor subunit 2 538841 6296085 HPSH_02815 Helicobacter pylori Shi470 molybdopterin converting factor subunit 2 YP_001910043.1 538404 D 512562 CDS YP_001910044.1 188527357 6296956 538854..539384 1 NC_010698.2 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 539384 mogA 6296956 mogA Helicobacter pylori Shi470 molybdenum cofactor biosynthesis protein MogA YP_001910044.1 538854 D 512562 CDS YP_001910045.1 188527358 6296362 539393..539869 1 NC_010698.2 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 539869 moaC 6296362 moaC Helicobacter pylori Shi470 molybdenum cofactor biosynthesis protein MoaC YP_001910045.1 539393 D 512562 CDS YP_001910046.1 188527359 6297081 539988..540770 1 NC_010698.2 flagellar sheath adhesin 540770 6297081 HPSH_02830 Helicobacter pylori Shi470 flagellar sheath adhesin YP_001910046.1 539988 D 512562 CDS YP_001910047.1 188527360 6296404 540796..541632 1 NC_010698.2 outer membrane protein 541632 6296404 HPSH_02835 Helicobacter pylori Shi470 outer membrane protein YP_001910047.1 540796 D 512562 CDS YP_001910048.1 188527361 6296898 541745..543100 1 NC_010698.2 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 543100 tig 6296898 tig Helicobacter pylori Shi470 trigger factor YP_001910048.1 541745 D 512562 CDS YP_001910049.1 188527362 6297355 543121..543708 1 NC_010698.2 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 543708 clpP 6297355 clpP Helicobacter pylori Shi470 ATP-dependent Clp protease proteolytic subunit YP_001910049.1 543121 D 512562 CDS YP_001910050.1 188527363 6296082 543713..544240 1 NC_010698.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 544240 def 6296082 def Helicobacter pylori Shi470 peptide deformylase YP_001910050.1 543713 D 512562 CDS YP_001910051.1 188527364 6296187 544243..545763 1 NC_010698.2 COG0606 Predicted ATPase with chaperone activity; sigma-54 interacting protein 545763 6296187 HPSH_02855 Helicobacter pylori Shi470 sigma-54 interacting protein YP_001910051.1 544243 D 512562 CDS YP_001910052.1 188527365 6296166 545788..547848 1 NC_010698.2 COG2217 Cation transport ATPase; cadmium-transporting ATPase 547848 6296166 HPSH_02860 Helicobacter pylori Shi470 cadmium-transporting ATPase YP_001910052.1 545788 D 512562 CDS YP_001910053.1 188527366 6296174 547884..549158 1 NC_010698.2 COG0732 Restriction endonuclease S subunits; anti-codon nuclease masking agent PrrB 549158 6296174 HPSH_02865 Helicobacter pylori Shi470 anti-codon nuclease masking agent PrrB YP_001910053.1 547884 D 512562 CDS YP_001910054.1 188527367 6296215 complement(549367..550866) 1 NC_010698.2 outer membrane protein HofF 550866 6296215 HPSH_02870 Helicobacter pylori Shi470 outer membrane protein HofF YP_001910054.1 549367 R 512562 CDS YP_001910055.1 188527368 6296332 complement(551146..552432) 1 NC_010698.2 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; lipoprotein release system transmembrane protein 552432 6296332 HPSH_02875 Helicobacter pylori Shi470 lipoprotein release system transmembrane protein YP_001910055.1 551146 R 512562 CDS YP_001910056.1 188527369 6296168 complement(552368..554965) 1 NC_010698.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 554965 6296168 HPSH_02880 Helicobacter pylori Shi470 preprotein translocase subunit SecA YP_001910056.1 552368 R 512562 CDS YP_001910057.1 188527370 6296053 555085..555666 1 NC_010698.2 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 555666 lolA 6296053 lolA Helicobacter pylori Shi470 outer-membrane lipoprotein carrier protein YP_001910057.1 555085 D 512562 CDS YP_001910058.1 188527371 6297030 complement(555691..555825) 1 NC_010698.2 hypothetical protein 555825 6297030 HPSH_02890 Helicobacter pylori Shi470 hypothetical protein YP_001910058.1 555691 R 512562 CDS YP_001910059.1 188527372 6296354 556159..556686 1 NC_010698.2 hypothetical protein 556686 6296354 HPSH_02895 Helicobacter pylori Shi470 hypothetical protein YP_001910059.1 556159 D 512562 CDS YP_001910060.1 188527373 6296392 complement(556693..558060) 1 NC_010698.2 hypothetical protein 558060 6296392 HPSH_02900 Helicobacter pylori Shi470 hypothetical protein YP_001910060.1 556693 R 512562 CDS YP_001910061.1 188527374 6296960 complement(558154..559443) 1 NC_010698.2 hypothetical protein 559443 6296960 HPSH_02905 Helicobacter pylori Shi470 hypothetical protein YP_001910061.1 558154 R 512562 CDS YP_001910062.1 188527375 6296895 complement(559843..559965) 1 NC_010698.2 hypothetical protein 559965 6296895 HPSH_02910 Helicobacter pylori Shi470 hypothetical protein YP_001910062.1 559843 R 512562 CDS YP_001910063.1 188527376 6296277 complement(560042..562600) 1 NC_010698.2 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 562600 6296277 HPSH_02915 Helicobacter pylori Shi470 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_001910063.1 560042 R 512562 CDS YP_001910064.1 188527377 6296271 562731..563414 1 NC_010698.2 COG1427 Predicted periplasmic solute-binding protein; hypothetical protein 563414 6296271 HPSH_02920 Helicobacter pylori Shi470 hypothetical protein YP_001910064.1 562731 D 512562 CDS YP_001910065.1 188527378 6296069 563524..564246 1 NC_010698.2 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 564246 pyrH 6296069 pyrH Helicobacter pylori Shi470 uridylate kinase YP_001910065.1 563524 D 512562 CDS YP_001910066.1 188527379 6296528 564289..564513 1 NC_010698.2 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 564513 6296528 HPSH_02930 Helicobacter pylori Shi470 DNA-directed RNA polymerase subunit omega YP_001910066.1 564289 D 512562 CDS YP_001910067.1 188527380 6296507 564500..566830 1 NC_010698.2 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; penta-phosphate guanosine-3'-pyrophosphohydrolase SpoT 566830 6296507 HPSH_02935 Helicobacter pylori Shi470 penta-phosphate guanosine-3'-pyrophosphohydrolase SpoT YP_001910067.1 564500 D 512562 CDS YP_001910068.1 188527381 6296005 566851..568059 1 NC_010698.2 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 568059 6296005 HPSH_02940 Helicobacter pylori Shi470 tyrosyl-tRNA synthetase YP_001910068.1 566851 D 512562 CDS YP_001910069.1 188527382 6296138 568070..569161 1 NC_010698.2 COG2070 Dioxygenases related to 2-nitropropane dioxygenase; hypothetical protein 569161 6296138 HPSH_02945 Helicobacter pylori Shi470 hypothetical protein YP_001910069.1 568070 D 512562 CDS YP_001910070.1 188527383 6297229 569168..570490 1 NC_010698.2 COG0860 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 570490 6297229 HPSH_02950 Helicobacter pylori Shi470 N-acetylmuramoyl-L-alanine amidase YP_001910070.1 569168 D 512562 CDS YP_001910071.1 188527384 6296284 570509..571246 1 NC_010698.2 hypothetical protein 571246 6296284 HPSH_02955 Helicobacter pylori Shi470 hypothetical protein YP_001910071.1 570509 D 512562 CDS YP_001910072.1 188527385 6296029 complement(572414..573019) 1 NC_010698.2 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 573019 6296029 HPSH_02970 Helicobacter pylori Shi470 molybdopterin-guanine dinucleotide biosynthesis protein A YP_001910072.1 572414 R 512562 CDS YP_001910073.1 188527386 6296057 573189..574070 1 NC_010698.2 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 574070 moaA 6296057 moaA Helicobacter pylori Shi470 molybdenum cofactor biosynthesis protein A YP_001910073.1 573189 D 512562 CDS YP_001910074.1 188527387 6296403 complement(574203..574412) 1 NC_010698.2 hypothetical protein 574412 6296403 HPSH_02980 Helicobacter pylori Shi470 hypothetical protein YP_001910074.1 574203 R 512562 CDS YP_001910075.1 188527388 6296071 574311..574646 1 NC_010698.2 hypothetical protein 574646 6296071 HPSH_02985 Helicobacter pylori Shi470 hypothetical protein YP_001910075.1 574311 D 512562 CDS YP_001910076.1 188527389 6296571 574528..574854 1 NC_010698.2 hypothetical protein 574854 6296571 HPSH_02990 Helicobacter pylori Shi470 hypothetical protein YP_001910076.1 574528 D 512562 CDS YP_001910077.1 188527390 6296327 574871..575764 1 NC_010698.2 COG1196 Chromosome segregation ATPases; hypothetical protein 575764 6296327 HPSH_02995 Helicobacter pylori Shi470 hypothetical protein YP_001910077.1 574871 D 512562 CDS YP_001910078.1 188527391 6297310 575776..576630 1 NC_010698.2 hypothetical protein 576630 6297310 HPSH_03000 Helicobacter pylori Shi470 hypothetical protein YP_001910078.1 575776 D 512562 CDS YP_001910079.1 188527392 6297208 576670..577035 1 NC_010698.2 COG0727 Predicted Fe-S-cluster oxidoreductase; hypothetical protein 577035 6297208 HPSH_03005 Helicobacter pylori Shi470 hypothetical protein YP_001910079.1 576670 D 512562 CDS YP_001910080.1 188527393 6297312 complement(577044..577937) 1 NC_010698.2 COG0552 Signal recognition particle GTPase; cell division protein FtsY 577937 6297312 HPSH_03010 Helicobacter pylori Shi470 cell division protein FtsY YP_001910080.1 577044 R 512562 CDS YP_001910081.1 188527394 6296179 complement(577944..578501) 1 NC_010698.2 hypothetical protein 578501 6296179 HPSH_03015 Helicobacter pylori Shi470 hypothetical protein YP_001910081.1 577944 R 512562 CDS YP_001910082.1 188527395 6296274 578626..579273 1 NC_010698.2 COG0212 5-formyltetrahydrofolate cyclo-ligase; hypothetical protein 579273 6296274 HPSH_03020 Helicobacter pylori Shi470 hypothetical protein YP_001910082.1 578626 D 512562 CDS YP_001910083.1 188527396 6296565 579251..580762 1 NC_010698.2 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 580762 6296565 HPSH_03025 Helicobacter pylori Shi470 phosphodiesterase YP_001910083.1 579251 D 512562 CDS YP_001910084.1 188527397 6296481 complement(580763..582016) 1 NC_010698.2 COG0534 Na+-driven multidrug efflux pump; hypothetical protein 582016 6296481 HPSH_03030 Helicobacter pylori Shi470 hypothetical protein YP_001910084.1 580763 R 512562 CDS YP_001910085.1 188527398 6296285 complement(582079..583392) 1 NC_010698.2 COG2056 Predicted permease; hypothetical protein 583392 6296285 HPSH_03035 Helicobacter pylori Shi470 hypothetical protein YP_001910085.1 582079 R 512562 CDS YP_001910086.1 188527399 6296272 complement(583386..583469) 1 NC_010698.2 hypothetical protein 583469 6296272 HPSH_03040 Helicobacter pylori Shi470 hypothetical protein YP_001910086.1 583386 R 512562 CDS YP_001910087.1 188527400 6296109 complement(583519..584397) 1 NC_010698.2 COG0388 Predicted amidohydrolase; carbon-nitrogen hydrolase 584397 6296109 HPSH_03045 Helicobacter pylori Shi470 carbon-nitrogen hydrolase YP_001910087.1 583519 R 512562 CDS YP_001910088.1 188527401 6296373 complement(584401..584547) 1 NC_010698.2 hypothetical protein 584547 6296373 HPSH_03050 Helicobacter pylori Shi470 hypothetical protein YP_001910088.1 584401 R 512562 CDS YP_001910089.1 188527402 6296451 complement(584576..585235) 1 NC_010698.2 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; molybdopterin biosynthesis protein 585235 6296451 HPSH_03055 Helicobacter pylori Shi470 molybdopterin biosynthesis protein YP_001910089.1 584576 R 512562 CDS YP_001910090.1 188527403 6296107 complement(585288..585527) 1 NC_010698.2 hypothetical protein 585527 6296107 HPSH_03060 Helicobacter pylori Shi470 hypothetical protein YP_001910090.1 585288 R 512562 CDS YP_001910091.1 188527404 6296856 complement(585514..585894) 1 NC_010698.2 flagellin specific chaperone; flagellar protein FliS 585894 fliS 6296856 fliS Helicobacter pylori Shi470 flagellar protein FliS YP_001910091.1 585514 R 512562 CDS YP_001910092.1 188527405 6296413 complement(585942..587999) 1 NC_010698.2 involved in flagellin assembly; flagellar capping protein 587999 fliD 6296413 fliD Helicobacter pylori Shi470 flagellar capping protein YP_001910092.1 585942 R 512562 CDS YP_001910093.1 188527406 6297320 complement(588016..588375) 1 NC_010698.2 possibly involved in flagella export; flagellar protein FlaG 588375 6297320 HPSH_03075 Helicobacter pylori Shi470 flagellar protein FlaG YP_001910093.1 588016 R 512562 CDS YP_001910094.1 188527407 6297123 complement(588470..589672) 1 NC_010698.2 COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 589672 6297123 HPSH_03080 Helicobacter pylori Shi470 hypothetical protein YP_001910094.1 588470 R 512562 CDS YP_001910095.1 188527408 6296216 complement(589665..590471) 1 NC_010698.2 COG2177 Cell division protein; cell division membrane protein FtsX 590471 6296216 HPSH_03085 Helicobacter pylori Shi470 cell division membrane protein FtsX YP_001910095.1 589665 R 512562 CDS YP_001910096.1 188527409 6296703 complement(590458..591129) 1 NC_010698.2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; cell division protein 591129 6296703 HPSH_03090 Helicobacter pylori Shi470 cell division protein YP_001910096.1 590458 R 512562 CDS YP_001910097.1 188527410 6296358 complement(591126..592307) 1 NC_010698.2 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 592307 trmB 6296358 trmB Helicobacter pylori Shi470 tRNA (guanine-N(7)-)-methyltransferase YP_001910097.1 591126 R 512562 CDS YP_001910098.1 188527411 6296059 complement(592318..593565) 1 NC_010698.2 COG3979 Uncharacterized protein contain chitin-binding domain type 3; hypothetical protein 593565 6296059 HPSH_03100 Helicobacter pylori Shi470 hypothetical protein YP_001910098.1 592318 R 512562 CDS YP_001910099.1 188527412 6297085 complement(593528..594511) 1 NC_010698.2 COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein 594511 6297085 HPSH_03105 Helicobacter pylori Shi470 hypothetical protein YP_001910099.1 593528 R 512562 CDS YP_001910100.1 188527413 6296243 595914..597035 1 NC_010698.2 COG0772 Bacterial cell division membrane protein; rod shape-determining protein MreB 597035 6296243 HPSH_03120 Helicobacter pylori Shi470 rod shape-determining protein MreB YP_001910100.1 595914 D 512562 CDS YP_001910101.1 188527414 6296183 complement(597129..598085) 1 NC_010698.2 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 598085 6296183 HPSH_03125 Helicobacter pylori Shi470 ribose-phosphate pyrophosphokinase YP_001910101.1 597129 R 512562 CDS YP_001910102.1 188527415 6296316 complement(598082..598153) 1 NC_010698.2 hypothetical protein 598153 6296316 HPSH_03130 Helicobacter pylori Shi470 hypothetical protein YP_001910102.1 598082 R 512562 CDS YP_001910103.1 188527416 6296340 complement(598150..598635) 1 NC_010698.2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; histidine triad (HIT) family protein 598635 6296340 HPSH_03135 Helicobacter pylori Shi470 histidine triad (HIT) family protein YP_001910103.1 598150 R 512562 CDS YP_001910104.1 188527417 6296223 complement(598645..600057) 1 NC_010698.2 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-MurNac-pentapeptide presynthetase MurF 600057 6296223 HPSH_03140 Helicobacter pylori Shi470 UDP-MurNac-pentapeptide presynthetase MurF YP_001910104.1 598645 R 512562 CDS YP_001910105.1 188527418 6296312 complement(600113..600835) 1 NC_010698.2 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase 600835 6296312 HPSH_03145 Helicobacter pylori Shi470 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase YP_001910105.1 600113 R 512562 CDS YP_001910106.1 188527419 6296480 complement(600835..601878) 1 NC_010698.2 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 601878 ddl 6296480 ddl Helicobacter pylori Shi470 D-alanyl-alanine synthetase A YP_001910106.1 600835 R 512562 CDS YP_001910107.1 188527420 6296081 complement(601956..602432) 1 NC_010698.2 COG1267 Phosphatidylglycerophosphatase A and related proteins; phosphatidylglycerophosphatase A 602432 6296081 HPSH_03155 Helicobacter pylori Shi470 phosphatidylglycerophosphatase A YP_001910107.1 601956 R 512562 CDS YP_001910108.1 188527421 6296066 602536..603690 1 NC_010698.2 COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; putative aminotransferase 603690 6296066 HPSH_03160 Helicobacter pylori Shi470 putative aminotransferase YP_001910108.1 602536 D 512562 CDS YP_001910109.1 188527422 6296188 603699..604160 1 NC_010698.2 COG2236 Predicted phosphoribosyltransferases; xanthine guanine phosphoribosyl transferase (gpt) 604160 6296188 HPSH_03165 Helicobacter pylori Shi470 xanthine guanine phosphoribosyl transferase (gpt) YP_001910109.1 603699 D 512562 CDS YP_001910110.1 188527423 6296122 604162..605481 1 NC_010698.2 COG0621 2-methylthioadenine synthetase; hypothetical protein 605481 6296122 HPSH_03170 Helicobacter pylori Shi470 hypothetical protein YP_001910110.1 604162 D 512562 CDS YP_001910111.1 188527424 6297017 605499..605726 1 NC_010698.2 hypothetical protein 605726 6297017 HPSH_03175 Helicobacter pylori Shi470 hypothetical protein YP_001910111.1 605499 D 512562 CDS YP_001910112.1 188527425 6296036 606787..607221 1 NC_010698.2 hypothetical protein 607221 6296036 HPSH_03190 Helicobacter pylori Shi470 hypothetical protein YP_001910112.1 606787 D 512562 CDS YP_001910113.1 188527426 6297137 608386..608691 1 NC_010698.2 COG0621 2-methylthioadenine synthetase; hypothetical protein 608691 6297137 HPSH_03210 Helicobacter pylori Shi470 hypothetical protein YP_001910113.1 608386 D 512562 CDS YP_001910114.1 188527427 6296342 608700..609767 1 NC_010698.2 hypothetical protein 609767 6296342 HPSH_03215 Helicobacter pylori Shi470 hypothetical protein YP_001910114.1 608700 D 512562 CDS YP_001910115.1 188527428 6296242 609790..610821 1 NC_010698.2 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; hypothetical protein 610821 6296242 HPSH_03220 Helicobacter pylori Shi470 hypothetical protein YP_001910115.1 609790 D 512562 CDS YP_001910116.1 188527429 6296411 610915..611901 1 NC_010698.2 COG0042 tRNA-dihydrouridine synthase; transcriptional regulator 611901 6296411 HPSH_03225 Helicobacter pylori Shi470 transcriptional regulator YP_001910116.1 610915 D 512562 CDS YP_001910117.1 188527430 6296255 611871..612788 1 NC_010698.2 outer membrane protein 612788 6296255 HPSH_03230 Helicobacter pylori Shi470 outer membrane protein YP_001910117.1 611871 D 512562 CDS YP_001910118.1 188527431 6296189 complement(615029..616360) 1 NC_010698.2 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 616360 6296189 HPSH_03245 Helicobacter pylori Shi470 anaerobic C4-dicarboxylate transporter YP_001910118.1 615029 R 512562 CDS YP_001910119.1 188527432 6296416 616445..617437 1 NC_010698.2 COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; L-asparaginase II 617437 6296416 HPSH_03250 Helicobacter pylori Shi470 L-asparaginase II YP_001910119.1 616445 D 512562 CDS YP_001910120.1 188527433 6296078 complement(617446..617643) 1 NC_010698.2 hypothetical protein 617643 6296078 HPSH_03255 Helicobacter pylori Shi470 hypothetical protein YP_001910120.1 617446 R 512562 CDS YP_001910121.1 188527434 6296076 complement(617777..617884) 1 NC_010698.2 hypothetical protein 617884 6296076 HPSH_03260 Helicobacter pylori Shi470 hypothetical protein YP_001910121.1 617777 R 512562 CDS YP_001910122.1 188527435 6296341 complement(617969..618439) 1 NC_010698.2 hypothetical protein 618439 6296341 HPSH_03265 Helicobacter pylori Shi470 hypothetical protein YP_001910122.1 617969 R 512562 CDS YP_001910123.1 188527436 6296249 complement(618468..618890) 1 NC_010698.2 hypothetical protein 618890 6296249 HPSH_03270 Helicobacter pylori Shi470 hypothetical protein YP_001910123.1 618468 R 512562 CDS YP_001910124.1 188527437 6296139 619157..619789 1 NC_010698.2 COG1279 Lysine efflux permease; hypothetical protein 619789 6296139 HPSH_03275 Helicobacter pylori Shi470 hypothetical protein YP_001910124.1 619157 D 512562 CDS YP_001910125.1 188527438 6296246 619858..621573 1 NC_010698.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 621573 6296246 HPSH_03280 Helicobacter pylori Shi470 DNA polymerase III subunits gamma and tau YP_001910125.1 619858 D 512562 CDS YP_001910126.1 188527439 6296314 621570..621971 1 NC_010698.2 COG0802 Predicted ATPase or kinase; hypothetical protein 621971 6296314 HPSH_03285 Helicobacter pylori Shi470 hypothetical protein YP_001910126.1 621570 D 512562 CDS YP_001910127.1 188527440 6297324 621984..622706 1 NC_010698.2 COG1137 ABC-type (unclassified) transport system, ATPase component; putative ABC transporter ATP-binding protein 622706 6297324 HPSH_03290 Helicobacter pylori Shi470 putative ABC transporter ATP-binding protein YP_001910127.1 621984 D 512562 CDS YP_001910128.1 188527441 6296247 622709..623953 1 NC_010698.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 623953 6296247 HPSH_03295 Helicobacter pylori Shi470 RNA polymerase factor sigma-54 YP_001910128.1 622709 D 512562 CDS YP_001910129.1 188527442 6297275 624274..625188 1 NC_010698.2 COG1012 NAD-dependent aldehyde dehydrogenases; outer membrane protein HopH 625188 6297275 HPSH_03300 Helicobacter pylori Shi470 outer membrane protein HopH YP_001910129.1 624274 D 512562 CDS YP_001910130.1 188527443 6296257 complement(625296..626516) 1 NC_010698.2 COG1896 Predicted hydrolases of HD superfamily; hypothetical protein 626516 6296257 HPSH_03305 Helicobacter pylori Shi470 hypothetical protein YP_001910130.1 625296 R 512562 CDS YP_001910131.1 188527444 6296019 complement(626961..627863) 1 NC_010698.2 COG1912 Uncharacterized conserved protein; hypothetical protein 627863 6296019 HPSH_03310 Helicobacter pylori Shi470 hypothetical protein YP_001910131.1 626961 R 512562 CDS YP_001910132.1 188527445 6297325 complement(628108..628452) 1 NC_010698.2 hypothetical protein 628452 6297325 HPSH_03315 Helicobacter pylori Shi470 hypothetical protein YP_001910132.1 628108 R 512562 CDS YP_001910133.1 188527446 6296984 complement(628472..629398) 1 NC_010698.2 COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW 629398 mraW 6296984 mraW Helicobacter pylori Shi470 S-adenosyl-methyltransferase MraW YP_001910133.1 628472 R 512562 CDS YP_001910134.1 188527447 6296925 complement(629598..630410) 1 NC_010698.2 Outer membrane protein/porin 630410 6296925 HPSH_03325 Helicobacter pylori Shi470 Outer membrane protein/porin YP_001910134.1 629598 R 512562 CDS YP_001910135.1 188527448 6297382 630594..633419 1 NC_010698.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 633419 uvrA 6297382 uvrA Helicobacter pylori Shi470 excinuclease ABC subunit A YP_001910135.1 630594 D 512562 CDS YP_001910136.1 188527449 6296261 complement(633606..634427) 1 NC_010698.2 hypothetical protein 634427 6296261 HPSH_03335 Helicobacter pylori Shi470 hypothetical protein YP_001910136.1 633606 R 512562 CDS YP_001910137.1 188527450 6296866 complement(634532..635677) 1 NC_010698.2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; transcriptional activator of flagella proteins 635677 6296866 HPSH_03340 Helicobacter pylori Shi470 transcriptional activator of flagella proteins YP_001910137.1 634532 R 512562 CDS YP_001910138.1 188527451 6297077 complement(635674..636129) 1 NC_010698.2 hypothetical protein 636129 6297077 HPSH_03345 Helicobacter pylori Shi470 hypothetical protein YP_001910138.1 635674 R 512562 CDS YP_001910139.1 188527452 6296014 complement(636147..638627) 1 NC_010698.2 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 638627 6296014 HPSH_03350 Helicobacter pylori Shi470 DNA gyrase subunit A YP_001910139.1 636147 R 512562 CDS YP_001910140.1 188527453 6296380 complement(638647..639033) 1 NC_010698.2 COG0818 Diacylglycerol kinase; diacylglycerol kinase 639033 6296380 HPSH_03355 Helicobacter pylori Shi470 diacylglycerol kinase YP_001910140.1 638647 R 512562 CDS YP_001910141.1 188527454 6297167 complement(639026..640039) 1 NC_010698.2 hypothetical protein 640039 6297167 HPSH_03360 Helicobacter pylori Shi470 hypothetical protein YP_001910141.1 639026 R 512562 CDS YP_001910142.1 188527455 6296015 complement(640362..640862) 1 NC_010698.2 COG4647 Acetone carboxylase, gamma subunit; hypothetical protein 640862 6296015 HPSH_03365 Helicobacter pylori Shi470 hypothetical protein YP_001910142.1 640362 R 512562 CDS YP_001910143.1 188527456 6296391 complement(640879..643176) 1 NC_010698.2 COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit; N-methylhydantoinase 643176 6296391 HPSH_03370 Helicobacter pylori Shi470 N-methylhydantoinase YP_001910143.1 640879 R 512562 CDS YP_001910144.1 188527457 6296301 complement(643188..645329) 1 NC_010698.2 COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit; hydantoin utilization protein A 645329 6296301 HPSH_03375 Helicobacter pylori Shi470 hydantoin utilization protein A YP_001910144.1 643188 R 512562 CDS YP_001910145.1 188527458 6296311 complement(645548..646549) 1 NC_010698.2 COG3528 Uncharacterized protein conserved in bacteria; putative outer membrane protein 646549 6296311 HPSH_03380 Helicobacter pylori Shi470 putative outer membrane protein YP_001910145.1 645548 R 512562 CDS YP_001910146.1 188527459 6296033 complement(646676..648040) 1 NC_010698.2 COG2031 Short chain fatty acids transporter; short-chain fatty acids transporter 648040 6296033 HPSH_03385 Helicobacter pylori Shi470 short-chain fatty acids transporter YP_001910146.1 646676 R 512562 CDS YP_001910147.1 188527460 6296357 647961..648104 1 NC_010698.2 hypothetical protein 648104 6296357 HPSH_03390 Helicobacter pylori Shi470 hypothetical protein YP_001910147.1 647961 D 512562 CDS YP_001910148.1 188527461 6296570 complement(648059..648682) 1 NC_010698.2 COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit; succinyl-CoA-transferase subunit B 648682 6296570 HPSH_03395 Helicobacter pylori Shi470 succinyl-CoA-transferase subunit B YP_001910148.1 648059 R 512562 CDS YP_001910149.1 188527462 6296267 complement(648679..649377) 1 NC_010698.2 COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; 3-oxoacid Coa-transferase subunit A 649377 6296267 HPSH_03400 Helicobacter pylori Shi470 3-oxoacid Coa-transferase subunit A YP_001910149.1 648679 R 512562 CDS YP_001910150.1 188527463 6297027 complement(649388..650563) 1 NC_010698.2 COG0183 Acetyl-CoA acetyltransferase; acetyl coenzyme A acetyltransferase FadA 650563 6297027 HPSH_03405 Helicobacter pylori Shi470 acetyl coenzyme A acetyltransferase FadA YP_001910150.1 649388 R 512562 CDS YP_001910151.1 188527464 6296278 complement(650820..651221) 1 NC_010698.2 COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; hypothetical protein 651221 6296278 HPSH_03410 Helicobacter pylori Shi470 hypothetical protein YP_001910151.1 650820 R 512562 CDS YP_001910152.1 188527465 6296398 complement(651311..652183) 1 NC_010698.2 putative type II restriction enzyme 652183 6296398 HPSH_03415 Helicobacter pylori Shi470 putative type II restriction enzyme YP_001910152.1 651311 R 512562 CDS YP_001910153.1 188527466 6296266 complement(652186..653400) 1 NC_010698.2 COG0863 DNA modification methylase; putative type II cytosine specific methyltransferase 653400 6296266 HPSH_03420 Helicobacter pylori Shi470 putative type II cytosine specific methyltransferase YP_001910153.1 652186 R 512562 CDS YP_001910154.1 188527467 6296113 complement(653455..654267) 1 NC_010698.2 COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; hypothetical protein 654267 6296113 HPSH_03425 Helicobacter pylori Shi470 hypothetical protein YP_001910154.1 653455 R 512562 CDS YP_001910155.1 188527468 6297158 654393..656339 1 NC_010698.2 COG0370 Fe2+ transport system protein B; iron(II) transport protein 656339 6297158 HPSH_03430 Helicobacter pylori Shi470 iron(II) transport protein YP_001910155.1 654393 D 512562 CDS YP_001910156.1 188527469 6297298 656582..658885 1 NC_010698.2 COG4772 Outer membrane receptor for Fe3+-dicitrate; iron(III) dicitrate transport protein 658885 6297298 HPSH_03435 Helicobacter pylori Shi470 iron(III) dicitrate transport protein YP_001910156.1 656582 D 512562 CDS YP_001910157.1 188527470 6296487 complement(658924..659670) 1 NC_010698.2 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 659670 fliP 6296487 fliP Helicobacter pylori Shi470 flagellar biosynthesis protein FliP YP_001910157.1 658924 R 512562 CDS YP_001910158.1 188527471 6297280 complement(659649..659801) 1 NC_010698.2 hypothetical protein 659801 6297280 HPSH_03445 Helicobacter pylori Shi470 hypothetical protein YP_001910158.1 659649 R 512562 CDS YP_001910159.1 188527472 6296486 659800..661059 1 NC_010698.2 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 661059 glmU 6296486 glmU Helicobacter pylori Shi470 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001910159.1 659800 D 512562 CDS YP_001910160.1 188527473 6296531 661324..661653 1 NC_010698.2 hypothetical protein 661653 6296531 HPSH_03455 Helicobacter pylori Shi470 hypothetical protein YP_001910160.1 661324 D 512562 CDS YP_001910161.1 188527474 6297103 661752..662150 1 NC_010698.2 hypothetical protein 662150 6297103 HPSH_03460 Helicobacter pylori Shi470 hypothetical protein YP_001910161.1 661752 D 512562 CDS YP_001910162.1 188527475 6296319 662322..664688 1 NC_010698.2 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 664688 6296319 HPSH_03465 Helicobacter pylori Shi470 ribonucleotide-diphosphate reductase subunit alpha YP_001910162.1 662322 D 512562 CDS YP_001910163.1 188527476 6296422 664750..665697 1 NC_010698.2 COG0673 Predicted dehydrogenases and related proteins; putative lipopolysaccharide biosynthesis protein 665697 6296422 HPSH_03470 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001910163.1 664750 D 512562 CDS YP_001910164.1 188527477 6297543 666524..667030 1 NC_010698.2 COG0350 Methylated DNA-protein cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase 667030 6297543 HPSH_03485 Helicobacter pylori Shi470 methylated-DNA--protein-cysteine methyltransferase YP_001910164.1 666524 D 512562 CDS YP_001910165.1 188527478 6296534 complement(667093..668163) 1 NC_010698.2 COG0582 Integrase; integrase-recombinase protein 668163 6296534 HPSH_03490 Helicobacter pylori Shi470 integrase-recombinase protein YP_001910165.1 667093 R 512562 CDS YP_001910166.1 188527479 6296330 complement(668170..668289) 1 NC_010698.2 hypothetical protein 668289 6296330 HPSH_03495 Helicobacter pylori Shi470 hypothetical protein YP_001910166.1 668170 R 512562 CDS YP_001910167.1 188527480 6296269 complement(668413..669585) 1 NC_010698.2 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 669585 6296269 HPSH_03500 Helicobacter pylori Shi470 aspartate aminotransferase YP_001910167.1 668413 R 512562 CDS YP_001910168.1 188527481 6296524 complement(669744..670556) 1 NC_010698.2 outer membrane protein HorF 670556 6296524 HPSH_03505 Helicobacter pylori Shi470 outer membrane protein HorF YP_001910168.1 669744 R 512562 CDS YP_001910169.1 188527482 6296463 complement(670659..670757) 1 NC_010698.2 hypothetical protein 670757 6296463 HPSH_03510 Helicobacter pylori Shi470 hypothetical protein YP_001910169.1 670659 R 512562 CDS YP_001910170.1 188527483 6296184 complement(670800..675029) 1 NC_010698.2 COG4889 Predicted helicase; hypothetical protein 675029 6296184 HPSH_03515 Helicobacter pylori Shi470 hypothetical protein YP_001910170.1 670800 R 512562 CDS YP_001910171.1 188527484 6296031 complement(674993..675625) 1 NC_010698.2 COG4889 Predicted helicase; hypothetical protein 675625 6296031 HPSH_03520 Helicobacter pylori Shi470 hypothetical protein YP_001910171.1 674993 R 512562 CDS YP_001910172.1 188527485 6296288 complement(675703..676992) 1 NC_010698.2 COG0247 Fe-S oxidoreductase; anaerobic glycerol-3-phosphate dehydrogenase subunit C 676992 6296288 HPSH_03525 Helicobacter pylori Shi470 anaerobic glycerol-3-phosphate dehydrogenase subunit C YP_001910172.1 675703 R 512562 CDS YP_001910173.1 188527486 6296365 complement(676989..678362) 1 NC_010698.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 678362 6296365 HPSH_03530 Helicobacter pylori Shi470 coproporphyrinogen III oxidase YP_001910173.1 676989 R 512562 CDS YP_001910174.1 188527487 6296127 complement(678362..678877) 1 NC_010698.2 hypothetical protein 678877 6296127 HPSH_03535 Helicobacter pylori Shi470 hypothetical protein YP_001910174.1 678362 R 512562 CDS YP_001910175.1 188527488 6297151 complement(678915..680012) 1 NC_010698.2 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 680012 6297151 HPSH_03540 Helicobacter pylori Shi470 chorismate synthase YP_001910175.1 678915 R 512562 CDS YP_001910176.1 188527489 6296226 complement(680009..680725) 1 NC_010698.2 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 680725 rnc 6296226 rnc Helicobacter pylori Shi470 ribonuclease III YP_001910176.1 680009 R 512562 CDS YP_001910177.1 188527490 6296163 complement(680700..681164) 1 NC_010698.2 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 681164 rnhA 6296163 rnhA Helicobacter pylori Shi470 ribonuclease H YP_001910177.1 680700 R 512562 CDS YP_001910178.1 188527491 6296143 complement(681151..682167) 1 NC_010698.2 COG2956 Predicted N-acetylglucosaminyl transferase; hypothetical protein 682167 6296143 HPSH_03555 Helicobacter pylori Shi470 hypothetical protein YP_001910178.1 681151 R 512562 CDS YP_001910179.1 188527492 6297207 complement(682178..683458) 1 NC_010698.2 COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein 683458 6297207 HPSH_03560 Helicobacter pylori Shi470 hypothetical protein YP_001910179.1 682178 R 512562 CDS YP_001910180.1 188527493 6296291 complement(683458..684882) 1 NC_010698.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 684882 gatB 6296291 gatB Helicobacter pylori Shi470 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001910180.1 683458 R 512562 CDS YP_001910181.1 188527494 6297156 complement(684882..686180) 1 NC_010698.2 COG0612 Predicted Zn-dependent peptidases; processing protease 686180 6297156 HPSH_03570 Helicobacter pylori Shi470 processing protease YP_001910181.1 684882 R 512562 CDS YP_001910182.1 188527495 6297079 complement(686183..687244) 1 NC_010698.2 COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; hypothetical protein 687244 6297079 HPSH_03575 Helicobacter pylori Shi470 hypothetical protein YP_001910182.1 686183 R 512562 CDS YP_001910183.1 188527496 6296389 complement(687246..689891) 1 NC_010698.2 COG4775 Outer membrane protein/protective antigen OMA87; protective surface antigen D15 689891 6296389 HPSH_03580 Helicobacter pylori Shi470 protective surface antigen D15 YP_001910183.1 687246 R 512562 CDS YP_001910184.1 188527497 6297121 complement(690064..691146) 1 NC_010698.2 COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; hypothetical protein 691146 6297121 HPSH_03585 Helicobacter pylori Shi470 hypothetical protein YP_001910184.1 690064 R 512562 CDS YP_001910185.1 188527498 6297041 691440..691943 1 NC_010698.2 COG1528 Ferritin-like protein; nonheme iron-containing ferritin 691943 6297041 HPSH_03590 Helicobacter pylori Shi470 nonheme iron-containing ferritin YP_001910185.1 691440 D 512562 CDS YP_001910186.1 188527499 6296128 691959..692582 1 NC_010698.2 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase SerB 692582 6296128 HPSH_03595 Helicobacter pylori Shi470 phosphoserine phosphatase SerB YP_001910186.1 691959 D 512562 CDS YP_001910187.1 188527500 6296265 692629..692712 1 NC_010698.2 hypothetical protein 692712 6296265 HPSH_03600 Helicobacter pylori Shi470 hypothetical protein YP_001910187.1 692629 D 512562 CDS YP_001910188.1 188527501 6296144 692721..693905 1 NC_010698.2 alpha-(1,3)-fucosyltransferase 693905 6296144 HPSH_03605 Helicobacter pylori Shi470 alpha-(1,3)-fucosyltransferase YP_001910188.1 692721 D 512562 CDS YP_001910189.1 188527502 6296902 complement(693914..694492) 1 NC_010698.2 COG1573 Uracil-DNA glycosylase; hypothetical protein 694492 6296902 HPSH_03610 Helicobacter pylori Shi470 hypothetical protein YP_001910189.1 693914 R 512562 CDS YP_001910190.1 188527503 6296118 complement(694549..695955) 1 NC_010698.2 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 695955 aspA 6296118 aspA Helicobacter pylori Shi470 aspartate ammonia-lyase YP_001910190.1 694549 R 512562 CDS YP_001910191.1 188527504 6297157 complement(696010..697278) 1 NC_010698.2 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 697278 6297157 HPSH_03620 Helicobacter pylori Shi470 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001910191.1 696010 R 512562 CDS YP_001910192.1 188527505 6296150 complement(697281..697688) 1 NC_010698.2 hypothetical protein 697688 6296150 HPSH_03625 Helicobacter pylori Shi470 hypothetical protein YP_001910192.1 697281 R 512562 CDS YP_001910193.1 188527506 6297323 complement(697700..698521) 1 NC_010698.2 COG1210 UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase 698521 6297323 HPSH_03630 Helicobacter pylori Shi470 UDP-glucose pyrophosphorylase YP_001910193.1 697700 R 512562 CDS YP_001910194.1 188527507 6296397 complement(698518..700200) 1 NC_010698.2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); soluble lytic murein transglycosylase 700200 6296397 HPSH_03635 Helicobacter pylori Shi470 soluble lytic murein transglycosylase YP_001910194.1 698518 R 512562 CDS YP_001910195.1 188527508 6296235 complement(700209..700502) 1 NC_010698.2 COG0762 Predicted integral membrane protein; hypothetical protein 700502 6296235 HPSH_03640 Helicobacter pylori Shi470 hypothetical protein YP_001910195.1 700209 R 512562 CDS YP_001910196.1 188527509 6296339 complement(700499..701818) 1 NC_010698.2 charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase 701818 6296339 HPSH_03645 Helicobacter pylori Shi470 glutamylglutaminyl-tRNA synthetase YP_001910196.1 700499 R 512562 CDS YP_001910197.1 188527510 6296158 complement(702712..702843) 1 NC_010698.2 hypothetical protein 702843 6296158 HPSH_03660 Helicobacter pylori Shi470 hypothetical protein YP_001910197.1 702712 R 512562 CDS YP_001910198.1 188527511 6296903 complement(702902..704068) 1 NC_010698.2 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; poly(A) polymerase 704068 6296903 HPSH_03665 Helicobacter pylori Shi470 poly(A) polymerase YP_001910198.1 702902 R 512562 CDS YP_001910199.1 188527512 6297089 704130..704810 1 NC_010698.2 COG0603 Predicted PP-loop superfamily ATPase; ExsB trans-regulatory protein 704810 6297089 HPSH_03670 Helicobacter pylori Shi470 ExsB trans-regulatory protein YP_001910199.1 704130 D 512562 CDS YP_001910200.1 188527513 6297201 complement(704856..705155) 1 NC_010698.2 outer membrane protein HopH 705155 6297201 HPSH_03675 Helicobacter pylori Shi470 outer membrane protein HopH YP_001910200.1 704856 R 512562 CDS YP_001910201.1 188527514 6296084 705979..706431 1 NC_010698.2 hypothetical protein 706431 6296084 HPSH_03680 Helicobacter pylori Shi470 hypothetical protein YP_001910201.1 705979 D 512562 CDS YP_001910202.1 188527515 6296054 706546..706959 1 NC_010698.2 hypothetical protein 706959 6296054 HPSH_03685 Helicobacter pylori Shi470 hypothetical protein YP_001910202.1 706546 D 512562 CDS YP_001910203.1 188527516 6297194 complement(706964..708502) 1 NC_010698.2 hypothetical protein 708502 6297194 HPSH_03690 Helicobacter pylori Shi470 hypothetical protein YP_001910203.1 706964 R 512562 CDS YP_001910204.1 188527517 6296569 complement(708504..709040) 1 NC_010698.2 COG0680 Ni,Fe-hydrogenase maturation factor; Hydrogenase expression/formation protein 709040 6296569 HPSH_03695 Helicobacter pylori Shi470 Hydrogenase expression/formation protein YP_001910204.1 708504 R 512562 CDS YP_001910205.1 188527518 6296521 complement(709037..709711) 1 NC_010698.2 COG1969 Ni,Fe-hydrogenase I cytochrome b subunit; quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit HydC 709711 6296521 HPSH_03700 Helicobacter pylori Shi470 quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit HydC YP_001910205.1 709037 R 512562 CDS YP_001910206.1 188527519 6297024 complement(709724..711460) 1 NC_010698.2 COG0374 Ni,Fe-hydrogenase I large subunit; quinone-reactive Ni/Fe hydrogenase HydB 711460 6297024 HPSH_03705 Helicobacter pylori Shi470 quinone-reactive Ni/Fe hydrogenase HydB YP_001910206.1 709724 R 512562 CDS YP_001910207.1 188527520 6296111 complement(711477..712631) 1 NC_010698.2 COG1740 Ni,Fe-hydrogenase I small subunit; Hydrogenase, small subunit 712631 6296111 HPSH_03710 Helicobacter pylori Shi470 Hydrogenase, small subunit YP_001910207.1 711477 R 512562 CDS YP_001910208.1 188527521 6297038 712766..713350 1 NC_010698.2 COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); modulator of drug activity 713350 6297038 HPSH_03715 Helicobacter pylori Shi470 modulator of drug activity YP_001910208.1 712766 D 512562 CDS YP_001910209.1 188527522 6296213 complement(713397..715442) 1 NC_010698.2 COG1479 Uncharacterized conserved protein; hypothetical protein 715442 6296213 HPSH_03720 Helicobacter pylori Shi470 hypothetical protein YP_001910209.1 713397 R 512562 CDS YP_001910210.1 188527523 6295999 complement(715567..716625) 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein F 716625 6295999 HPSH_03725 Helicobacter pylori Shi470 cysteine-rich protein F YP_001910210.1 715567 R 512562 CDS YP_001910211.1 188527524 6296010 complement(716637..717842) 1 NC_010698.2 COG2171 Tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate N-succinyltransferase DapD 717842 6296010 HPSH_03730 Helicobacter pylori Shi470 tetrahydrodipicolinate N-succinyltransferase DapD YP_001910211.1 716637 R 512562 CDS YP_001910212.1 188527525 6296350 complement(717845..718924) 1 NC_010698.2 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 718924 ispG 6296350 ispG Helicobacter pylori Shi470 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001910212.1 717845 R 512562 CDS YP_001910213.1 188527526 6296290 719044..720171 1 NC_010698.2 COG0436 Aspartate/tyrosine/aromatic aminotransferase; hypothetical protein 720171 6296290 HPSH_03740 Helicobacter pylori Shi470 hypothetical protein YP_001910213.1 719044 D 512562 CDS YP_001910214.1 188527527 6296240 720164..721513 1 NC_010698.2 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 721513 murC 6296240 murC Helicobacter pylori Shi470 UDP-N-acetylmuramate--L-alanine ligase YP_001910214.1 720164 D 512562 CDS YP_001910215.1 188527528 6296983 721513..721878 1 NC_010698.2 hypothetical protein 721878 6296983 HPSH_03750 Helicobacter pylori Shi470 hypothetical protein YP_001910215.1 721513 D 512562 CDS YP_001910216.1 188527529 6296093 721885..724134 1 NC_010698.2 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 724134 6296093 HPSH_03755 Helicobacter pylori Shi470 recombination and DNA strand exchange inhibitor protein YP_001910216.1 721885 D 512562 CDS YP_001910217.1 188527530 6296221 complement(724282..724803) 1 NC_010698.2 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 724803 6296221 HPSH_03760 Helicobacter pylori Shi470 inorganic pyrophosphatase YP_001910217.1 724282 R 512562 CDS YP_001910218.1 188527531 6296212 complement(724859..725614) 1 NC_010698.2 COG0840 Methyl-accepting chemotaxis protein; putative lipopolysaccharide biosynthesis protein 725614 6296212 HPSH_03765 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001910218.1 724859 R 512562 CDS YP_001910219.1 188527532 6296325 complement(725560..726210) 1 NC_010698.2 COG3306 Glycosyltransferase involved in LPS biosynthesis; putative lipopolysaccharide biosynthesis protein 726210 6296325 HPSH_03770 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001910219.1 725560 R 512562 CDS YP_001910220.1 188527533 6296231 complement(726217..727215) 1 NC_010698.2 COG3306 Glycosyltransferase involved in LPS biosynthesis; putative lipopolysaccharide biosynthesis protein 727215 6296231 HPSH_03775 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001910220.1 726217 R 512562 CDS YP_001910221.1 188527534 6296256 complement(727240..727815) 1 NC_010698.2 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 727815 adk 6296256 adk Helicobacter pylori Shi470 adenylate kinase YP_001910221.1 727240 R 512562 CDS YP_001910222.1 188527535 6296229 complement(727832..729565) 1 NC_010698.2 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 729565 aspS 6296229 aspS Helicobacter pylori Shi470 aspartyl-tRNA synthetase YP_001910222.1 727832 R 512562 CDS YP_001910223.1 188527536 6296200 complement(729600..730541) 1 NC_010698.2 COG0835 Chemotaxis signal transduction protein; chemotaxis protein 730541 6296200 HPSH_03790 Helicobacter pylori Shi470 chemotaxis protein YP_001910223.1 729600 R 512562 CDS YP_001910224.1 188527537 6297250 730619..732589 1 NC_010698.2 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 732589 ligA 6297250 ligA Helicobacter pylori Shi470 NAD-dependent DNA ligase LigA YP_001910224.1 730619 D 512562 CDS YP_001910225.1 188527538 6296016 732690..733022 1 NC_010698.2 COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; hypothetical protein 733022 6296016 HPSH_03800 Helicobacter pylori Shi470 hypothetical protein YP_001910225.1 732690 D 512562 CDS YP_001910226.1 188527539 6296490 733594..734052 1 NC_010698.2 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 734052 6296490 HPSH_03805 Helicobacter pylori Shi470 putative ABC transporter ATP-binding protein YP_001910226.1 733594 D 512562 CDS YP_001910227.1 188527540 6296009 734052..734801 1 NC_010698.2 COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 734801 6296009 HPSH_03810 Helicobacter pylori Shi470 hypothetical protein YP_001910227.1 734052 D 512562 CDS YP_001910228.1 188527541 6297033 complement(734861..744430) 1 NC_010698.2 putative vacuolating cytotoxin (VacA)-like protein 744430 6297033 HPSH_03815 Helicobacter pylori Shi470 putative vacuolating cytotoxin (VacA)-like protein YP_001910228.1 734861 R 512562 CDS YP_001910229.1 188527542 6296466 complement(744569..745138) 1 NC_010698.2 COG0015 Adenylosuccinate lyase; hypothetical protein 745138 6296466 HPSH_03820 Helicobacter pylori Shi470 hypothetical protein YP_001910229.1 744569 R 512562 CDS YP_001910230.1 188527543 6297122 complement(745135..748221) 1 NC_010698.2 COG0841 Cation/multidrug efflux pump; cytoplasmic pump protein of the hefABC efflux system HefC 748221 6297122 HPSH_03825 Helicobacter pylori Shi470 cytoplasmic pump protein of the hefABC efflux system HefC YP_001910230.1 745135 R 512562 CDS YP_001910231.1 188527544 6297139 complement(748234..748938) 1 NC_010698.2 COG0845 Membrane-fusion protein; membrane fusion protein of the hefABC efflux system HefB 748938 6297139 HPSH_03830 Helicobacter pylori Shi470 membrane fusion protein of the hefABC efflux system HefB YP_001910231.1 748234 R 512562 CDS YP_001910232.1 188527545 6296251 complement(748948..750381) 1 NC_010698.2 COG1538 Outer membrane protein; outer-membrane protein of the hefABC efflux system HefA 750381 6296251 HPSH_03835 Helicobacter pylori Shi470 outer-membrane protein of the hefABC efflux system HefA YP_001910232.1 748948 R 512562 CDS YP_001910233.1 188527546 6296136 complement(750392..751411) 1 NC_010698.2 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 751411 hemE 6296136 hemE Helicobacter pylori Shi470 uroporphyrinogen decarboxylase YP_001910233.1 750392 R 512562 CDS YP_001910234.1 188527547 6296346 complement(751477..752046) 1 NC_010698.2 hypothetical protein 752046 6296346 HPSH_03845 Helicobacter pylori Shi470 hypothetical protein YP_001910234.1 751477 R 512562 CDS YP_001910235.1 188527548 6296407 complement(752091..752747) 1 NC_010698.2 COG2231 Uncharacterized protein related to Endonuclease III; 3-methyladenine DNA glycosylase 752747 6296407 HPSH_03850 Helicobacter pylori Shi470 3-methyladenine DNA glycosylase YP_001910235.1 752091 R 512562 CDS YP_001910236.1 188527549 6297500 complement(752865..754397) 1 NC_010698.2 FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A 754397 6297500 HPSH_03855 Helicobacter pylori Shi470 flagellin A YP_001910236.1 752865 R 512562 CDS YP_001910237.1 188527550 6296840 754561..755325 1 NC_010698.2 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative secretion/efflux ABC transporter ATP-binding protein 755325 6296840 HPSH_03860 Helicobacter pylori Shi470 putative secretion/efflux ABC transporter ATP-binding protein YP_001910237.1 754561 D 512562 CDS YP_001910238.1 188527551 6296308 755395..756342 1 NC_010698.2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein SpaB 756342 6296308 HPSH_03865 Helicobacter pylori Shi470 multidrug resistance protein SpaB YP_001910238.1 755395 D 512562 CDS YP_001910239.1 188527552 6296087 756414..757715 1 NC_010698.2 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein 757715 6296087 HPSH_03870 Helicobacter pylori Shi470 methyl-accepting chemotaxis protein YP_001910239.1 756414 D 512562 CDS YP_001910240.1 188527553 6296526 757738..758859 1 NC_010698.2 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase BioF 758859 6296526 HPSH_03875 Helicobacter pylori Shi470 8-amino-7-oxononanoate synthase BioF YP_001910240.1 757738 D 512562 CDS YP_001910241.1 188527554 6296089 758859..760838 1 NC_010698.2 COG0744 Membrane carboxypeptidase (penicillin-binding protein); penicillin-binding protein 1A 760838 6296089 HPSH_03880 Helicobacter pylori Shi470 penicillin-binding protein 1A YP_001910241.1 758859 D 512562 CDS YP_001910242.1 188527555 6297179 complement(760841..761419) 1 NC_010698.2 Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein 761419 6297179 HPSH_03885 Helicobacter pylori Shi470 tumor necrosis factor alpha-inducing protein YP_001910242.1 760841 R 512562 CDS YP_001910243.1 188527556 6297063 761578..761697 1 NC_010698.2 hypothetical protein 761697 6297063 HPSH_03890 Helicobacter pylori Shi470 hypothetical protein YP_001910243.1 761578 D 512562 CDS YP_001910244.1 188527557 6296313 complement(761895..763367) 1 NC_010698.2 COG1495 Disulfide bond formation protein DsbB; DsbB-like protein 763367 6296313 HPSH_03895 Helicobacter pylori Shi470 DsbB-like protein YP_001910244.1 761895 R 512562 CDS YP_001910245.1 188527558 6296178 complement(763376..763540) 1 NC_010698.2 hypothetical protein 763540 6296178 HPSH_03900 Helicobacter pylori Shi470 hypothetical protein YP_001910245.1 763376 R 512562 CDS YP_001910246.1 188527559 6297305 complement(763680..765458) 1 NC_010698.2 COG5610 Predicted hydrolase (HAD superfamily); hypothetical protein 765458 6297305 HPSH_03905 Helicobacter pylori Shi470 hypothetical protein YP_001910246.1 763680 R 512562 CDS YP_001910247.1 188527560 6296182 complement(765566..766120) 1 NC_010698.2 COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; 2-oxoglutarate-acceptor oxidoreductase subunit OorC 766120 oorC 6296182 oorC Helicobacter pylori Shi470 2-oxoglutarate-acceptor oxidoreductase subunit OorC YP_001910247.1 765566 R 512562 CDS YP_001910248.1 188527561 6296408 complement(766120..766941) 1 NC_010698.2 COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; 2-oxoglutarate-acceptor oxidoreductase subunit OorB 766941 oorB 6296408 oorB Helicobacter pylori Shi470 2-oxoglutarate-acceptor oxidoreductase subunit OorB YP_001910248.1 766120 R 512562 CDS YP_001910249.1 188527562 6296106 complement(766943..768070) 1 NC_010698.2 COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; 2-oxoglutarate-acceptor oxidoreductase subunit OorA 768070 oorA 6296106 oorA Helicobacter pylori Shi470 2-oxoglutarate-acceptor oxidoreductase subunit OorA YP_001910249.1 766943 R 512562 CDS YP_001910250.1 188527563 6296452 complement(768070..768411) 1 NC_010698.2 COG1146 Ferredoxin; 2-oxoglutarate-acceptor oxidoreductase subunit OorD 768411 oorD 6296452 oorD Helicobacter pylori Shi470 2-oxoglutarate-acceptor oxidoreductase subunit OorD YP_001910250.1 768070 R 512562 CDS YP_001910251.1 188527564 6296125 complement(768399..768491) 1 NC_010698.2 hypothetical protein 768491 6296125 HPSH_03930 Helicobacter pylori Shi470 hypothetical protein YP_001910251.1 768399 R 512562 CDS YP_001910252.1 188527565 6296387 complement(768587..769519) 1 NC_010698.2 COG1559 Predicted periplasmic solute-binding protein; aminodeoxychorismate lyase PabC 769519 6296387 HPSH_03935 Helicobacter pylori Shi470 aminodeoxychorismate lyase PabC YP_001910252.1 768587 R 512562 CDS YP_001910253.1 188527566 6296137 769500..772433 1 NC_010698.2 hypothetical protein 772433 6296137 HPSH_03940 Helicobacter pylori Shi470 hypothetical protein YP_001910253.1 769500 D 512562 CDS YP_001910254.1 188527567 6296153 772435..772665 1 NC_010698.2 COG1918 Fe2+ transport system protein A; hypothetical protein 772665 6296153 HPSH_03945 Helicobacter pylori Shi470 hypothetical protein YP_001910254.1 772435 D 512562 CDS YP_001910255.1 188527568 6296924 772662..773318 1 NC_010698.2 COG0177 Predicted EndoIII-related endonuclease; endonuclease III 773318 6296924 HPSH_03950 Helicobacter pylori Shi470 endonuclease III YP_001910255.1 772662 D 512562 CDS YP_001910256.1 188527569 6296399 773400..773771 1 NC_010698.2 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 773771 6296399 HPSH_03955 Helicobacter pylori Shi470 flagellar motor switch protein YP_001910256.1 773400 D 512562 CDS YP_001910257.1 188527570 6297366 773783..774649 1 NC_010698.2 hypothetical protein 774649 6297366 HPSH_03960 Helicobacter pylori Shi470 hypothetical protein YP_001910257.1 773783 D 512562 CDS YP_001910258.1 188527571 6297047 774633..775580 1 NC_010698.2 COG0810 Periplasmic protein TonB, links inner and outer membranes; hypothetical protein 775580 6297047 HPSH_03965 Helicobacter pylori Shi470 hypothetical protein YP_001910258.1 774633 D 512562 CDS YP_001910259.1 188527572 6296453 775584..776603 1 NC_010698.2 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 776603 6296453 HPSH_03970 Helicobacter pylori Shi470 dihydroorotase YP_001910259.1 775584 D 512562 CDS YP_001910260.1 188527573 6296185 776579..777697 1 NC_010698.2 COG4692 Predicted neuraminidase (sialidase); hypothetical protein 777697 6296185 HPSH_03975 Helicobacter pylori Shi470 hypothetical protein YP_001910260.1 776579 D 512562 CDS YP_001910261.1 188527574 6296073 777704..778258 1 NC_010698.2 hypothetical protein 778258 6296073 HPSH_03980 Helicobacter pylori Shi470 hypothetical protein YP_001910261.1 777704 D 512562 CDS YP_001910262.1 188527575 6296296 778264..780291 1 NC_010698.2 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; hypothetical protein 780291 6296296 HPSH_03985 Helicobacter pylori Shi470 hypothetical protein YP_001910262.1 778264 D 512562 CDS YP_001910263.1 188527576 6296414 780368..781240 1 NC_010698.2 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 781240 6296414 HPSH_03990 Helicobacter pylori Shi470 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001910263.1 780368 D 512562 CDS YP_001910264.1 188527577 6296039 781241..782113 1 NC_010698.2 COG0681 Signal peptidase I; signal peptidase I (lepB) 782113 6296039 HPSH_03995 Helicobacter pylori Shi470 signal peptidase I (lepB) YP_001910264.1 781241 D 512562 CDS YP_001910265.1 188527578 6297090 782122..782820 1 NC_010698.2 COG1994 Zn-dependent proteases; hypothetical protein 782820 6297090 HPSH_04000 Helicobacter pylori Shi470 hypothetical protein YP_001910265.1 782122 D 512562 CDS YP_001910266.1 188527579 6297599 782841..783296 1 NC_010698.2 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 783296 6297599 HPSH_04005 Helicobacter pylori Shi470 ribose-5-phosphate isomerase B YP_001910266.1 782841 D 512562 CDS YP_001910267.1 188527580 6297598 783349..783681 1 NC_010698.2 hypothetical protein 783681 6297598 HPSH_04010 Helicobacter pylori Shi470 hypothetical protein YP_001910267.1 783349 D 512562 CDS YP_001910268.1 188527581 6297597 783739..784278 1 NC_010698.2 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 784278 6297597 HPSH_04015 Helicobacter pylori Shi470 adenine phosphoribosyltransferase YP_001910268.1 783739 D 512562 CDS YP_001910269.1 188527582 6297596 784293..784871 1 NC_010698.2 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 784871 6297596 HPSH_04020 Helicobacter pylori Shi470 hypothetical protein YP_001910269.1 784293 D 512562 CDS YP_001910270.1 188527583 6297595 784933..786423 1 NC_010698.2 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 786423 6297595 HPSH_04025 Helicobacter pylori Shi470 leucyl aminopeptidase YP_001910270.1 784933 D 512562 CDS YP_001910271.1 188527584 6297594 786425..787525 1 NC_010698.2 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 787525 6297594 HPSH_04030 Helicobacter pylori Shi470 GTP-dependent nucleic acid-binding protein EngD YP_001910271.1 786425 D 512562 CDS YP_001910272.1 188527585 6297579 787559..788431 1 NC_010698.2 COG0535 Predicted Fe-S oxidoreductases; hypothetical protein 788431 6297579 HPSH_04035 Helicobacter pylori Shi470 hypothetical protein YP_001910272.1 787559 D 512562 CDS YP_001910273.1 188527586 6296303 complement(788507..789553) 1 NC_010698.2 COG0628 Predicted permease; membrane protein 789553 6296303 HPSH_04040 Helicobacter pylori Shi470 membrane protein YP_001910273.1 788507 R 512562 CDS YP_001910274.1 188527587 6297048 789668..790489 1 NC_010698.2 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 790489 dapF 6297048 dapF Helicobacter pylori Shi470 diaminopimelate epimerase YP_001910274.1 789668 D 512562 CDS YP_001910275.1 188527588 6297592 790596..791243 1 NC_010698.2 COG3059 Predicted membrane protein; hypothetical protein 791243 6297592 HPSH_04050 Helicobacter pylori Shi470 hypothetical protein YP_001910275.1 790596 D 512562 CDS YP_001910276.1 188527589 6297591 complement(791267..791509) 1 NC_010698.2 hypothetical protein 791509 6297591 HPSH_04055 Helicobacter pylori Shi470 hypothetical protein YP_001910276.1 791267 R 512562 CDS YP_001910277.1 188527590 6297590 791682..792932 1 NC_010698.2 hypothetical protein 792932 6297590 HPSH_04060 Helicobacter pylori Shi470 hypothetical protein YP_001910277.1 791682 D 512562 CDS YP_001910278.1 188527591 6297589 793034..793246 1 NC_010698.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 793246 rpsU 6297589 rpsU Helicobacter pylori Shi470 30S ribosomal protein S21 YP_001910278.1 793034 D 512562 CDS YP_001910279.1 188527592 6297588 793283..794026 1 NC_010698.2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 794026 fabG 6297588 fabG Helicobacter pylori Shi470 3-ketoacyl-(acyl-carrier-protein) reductase YP_001910279.1 793283 D 512562 CDS YP_001910280.1 188527593 6297587 794256..794492 1 NC_010698.2 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 794492 acpP 6297587 acpP Helicobacter pylori Shi470 acyl carrier protein YP_001910280.1 794256 D 512562 CDS YP_001910281.1 188527594 6297586 794682..794789 1 NC_010698.2 hypothetical protein 794789 6297586 HPSH_04080 Helicobacter pylori Shi470 hypothetical protein YP_001910281.1 794682 D 512562 CDS YP_001910282.1 188527595 6297585 794805..796043 1 NC_010698.2 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 796043 6297585 HPSH_04085 Helicobacter pylori Shi470 3-oxoacyl-(acyl carrier protein) synthase II YP_001910282.1 794805 D 512562 CDS YP_001910283.1 188527596 6297584 796066..797004 1 NC_010698.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 797004 6297584 HPSH_04090 Helicobacter pylori Shi470 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001910283.1 796066 D 512562 CDS YP_001910284.1 188527597 6297583 797117..797206 1 NC_010698.2 hypothetical protein 797206 6297583 HPSH_04095 Helicobacter pylori Shi470 hypothetical protein YP_001910284.1 797117 D 512562 CDS YP_001910286.1 188527599 6297581 797415..797612 1 NC_010698.2 hypothetical protein 797612 6297581 HPSH_04105 Helicobacter pylori Shi470 hypothetical protein YP_001910286.1 797415 D 512562 CDS YP_001910287.1 188527600 6297580 complement(797699..798520) 1 NC_010698.2 hypothetical protein 798520 6297580 HPSH_04110 Helicobacter pylori Shi470 hypothetical protein YP_001910287.1 797699 R 512562 CDS YP_001910288.1 188527601 6297593 complement(798517..799491) 1 NC_010698.2 hypothetical protein 799491 6297593 HPSH_04115 Helicobacter pylori Shi470 hypothetical protein YP_001910288.1 798517 R 512562 CDS YP_001910289.1 188527602 6297576 complement(799504..800187) 1 NC_010698.2 COG0566 rRNA methylases; hypothetical protein 800187 6297576 HPSH_04120 Helicobacter pylori Shi470 hypothetical protein YP_001910289.1 799504 R 512562 CDS YP_001910290.1 188527603 6297575 complement(800200..801063) 1 NC_010698.2 COG0313 Predicted methyltransferases; hypothetical protein 801063 6297575 HPSH_04125 Helicobacter pylori Shi470 hypothetical protein YP_001910290.1 800200 R 512562 CDS YP_001910291.1 188527604 6297574 complement(801088..801291) 1 NC_010698.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 801291 rpmE 6297574 rpmE Helicobacter pylori Shi470 50S ribosomal protein L31 YP_001910291.1 801088 R 512562 CDS YP_001910292.1 188527605 6297573 801553..802869 1 NC_010698.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 802869 rho 6297573 rho Helicobacter pylori Shi470 transcription termination factor Rho YP_001910292.1 801553 D 512562 CDS YP_001910293.1 188527606 6297572 802905..803672 1 NC_010698.2 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 803672 6297572 HPSH_04140 Helicobacter pylori Shi470 glutamate racemase YP_001910293.1 802905 D 512562 CDS YP_001910294.1 188527607 6297571 complement(804109..807594) 1 NC_010698.2 cag pathogenicity island protein CagA 807594 6297571 HPSH_04145 Helicobacter pylori Shi470 cag pathogenicity island protein CagA YP_001910294.1 804109 R 512562 CDS YP_001910295.1 188527608 6297570 808001..808228 1 NC_010698.2 cag pathogenicity island protein CagB 808228 6297570 HPSH_04150 Helicobacter pylori Shi470 cag pathogenicity island protein CagB YP_001910295.1 808001 D 512562 CDS YP_001910296.1 188527609 6297569 808395..808742 1 NC_010698.2 cag pathogenicity island protein CagC 808742 6297569 HPSH_04155 Helicobacter pylori Shi470 cag pathogenicity island protein CagC YP_001910296.1 808395 D 512562 CDS YP_001910297.1 188527610 6297568 808744..809367 1 NC_010698.2 cag pathogenicity island protein CagD 809367 6297568 HPSH_04160 Helicobacter pylori Shi470 cag pathogenicity island protein CagD YP_001910297.1 808744 D 512562 CDS YP_001910298.1 188527611 6297567 809382..812327 1 NC_010698.2 COG3451 Type IV secretory pathway, VirB4 components; cag pathogenicity island protein CagE 812327 6297567 HPSH_04165 Helicobacter pylori Shi470 cag pathogenicity island protein CagE YP_001910298.1 809382 D 512562 CDS YP_001910299.1 188527612 6297566 812329..813135 1 NC_010698.2 cag pathogenicity island protein CagF 813135 6297566 HPSH_04170 Helicobacter pylori Shi470 cag pathogenicity island protein CagF YP_001910299.1 812329 D 512562 CDS YP_001910300.1 188527613 6297565 813190..813621 1 NC_010698.2 cag pathogenicity island protein CagG 813621 6297565 HPSH_04175 Helicobacter pylori Shi470 cag pathogenicity island protein CagG YP_001910300.1 813190 D 512562 CDS YP_001910301.1 188527614 6297564 complement(813607..813804) 1 NC_010698.2 hypothetical protein 813804 6297564 HPSH_04180 Helicobacter pylori Shi470 hypothetical protein YP_001910301.1 813607 R 512562 CDS YP_001910302.1 188527615 6297563 813803..814735 1 NC_010698.2 COG0249 Mismatch repair ATPase (MutS family); cag pathogenicity island protein CagH 814735 6297563 HPSH_04185 Helicobacter pylori Shi470 cag pathogenicity island protein CagH YP_001910302.1 813803 D 512562 CDS YP_001910303.1 188527616 6297562 814746..815885 1 NC_010698.2 cag pathogenicity island protein CagI 815885 6297562 HPSH_04190 Helicobacter pylori Shi470 cag pathogenicity island protein CagI YP_001910303.1 814746 D 512562 CDS YP_001910304.1 188527617 6297561 815882..816595 1 NC_010698.2 cag pathogenicity island protein CagL 816595 6297561 HPSH_04195 Helicobacter pylori Shi470 cag pathogenicity island protein CagL YP_001910304.1 815882 D 512562 CDS YP_001910305.1 188527618 6297560 complement(816678..817598) 1 NC_010698.2 cag pathogenicity island protein CagN 817598 6297560 HPSH_04200 Helicobacter pylori Shi470 cag pathogenicity island protein CagN YP_001910305.1 816678 R 512562 CDS YP_001910306.1 188527619 6297559 complement(817613..818743) 1 NC_010698.2 cag pathogenicity island protein CagM 818743 6297559 HPSH_04205 Helicobacter pylori Shi470 cag pathogenicity island protein CagM YP_001910306.1 817613 R 512562 CDS YP_001910307.1 188527620 6297558 819169..819513 1 NC_010698.2 cag pathogenicity island protein CagP 819513 6297558 HPSH_04210 Helicobacter pylori Shi470 cag pathogenicity island protein CagP YP_001910307.1 819169 D 512562 CDS YP_001910308.1 188527621 6297557 complement(819912..823169) 1 NC_010698.2 cag pathogenicity island protein CagA 823169 6297557 HPSH_04215 Helicobacter pylori Shi470 cag pathogenicity island protein CagA YP_001910308.1 819912 R 512562 CDS YP_001910309.1 188527622 6297458 823362..823460 1 NC_010698.2 hypothetical protein 823460 6297458 HPSH_04220 Helicobacter pylori Shi470 hypothetical protein YP_001910309.1 823362 D 512562 CDS YP_001910310.1 188527623 6296919 823481..823708 1 NC_010698.2 cag pathogenicity island protein CagB 823708 6296919 HPSH_04225 Helicobacter pylori Shi470 cag pathogenicity island protein CagB YP_001910310.1 823481 D 512562 CDS YP_001910311.1 188527624 6296543 823876..824067 1 NC_010698.2 cag pathogenicity island protein CagC 824067 6296543 HPSH_04230 Helicobacter pylori Shi470 cag pathogenicity island protein CagC YP_001910311.1 823876 D 512562 CDS YP_001910312.1 188527625 6297555 824137..824232 1 NC_010698.2 hypothetical protein 824232 6297555 HPSH_04235 Helicobacter pylori Shi470 hypothetical protein YP_001910312.1 824137 D 512562 CDS YP_001910313.1 188527626 6297554 complement(824858..825163) 1 NC_010698.2 cag pathogenicity island protein CagQ 825163 6297554 HPSH_04240 Helicobacter pylori Shi470 cag pathogenicity island protein CagQ YP_001910313.1 824858 R 512562 CDS YP_001910314.1 188527627 6297553 complement(825192..825374) 1 NC_010698.2 hypothetical protein 825374 6297553 HPSH_04245 Helicobacter pylori Shi470 hypothetical protein YP_001910314.1 825192 R 512562 CDS YP_001910315.1 188527628 6297552 825507..825644 1 NC_010698.2 hypothetical protein 825644 6297552 HPSH_04250 Helicobacter pylori Shi470 hypothetical protein YP_001910315.1 825507 D 512562 CDS YP_001910316.1 188527629 6297551 826078..826677 1 NC_010698.2 cag pathogenicity island protein CagS 826677 6297551 HPSH_04255 Helicobacter pylori Shi470 cag pathogenicity island protein CagS YP_001910316.1 826078 D 512562 CDS YP_001910317.1 188527630 6297550 complement(826879..827721) 1 NC_010698.2 cag pathogenicity island protein CagT 827721 6297550 HPSH_04260 Helicobacter pylori Shi470 cag pathogenicity island protein CagT YP_001910317.1 826879 R 512562 CDS YP_001910318.1 188527631 6297549 complement(827737..828384) 1 NC_010698.2 cag pathogenicity island protein CagU 828384 6297549 HPSH_04265 Helicobacter pylori Shi470 cag pathogenicity island protein CagU YP_001910318.1 827737 R 512562 CDS YP_001910319.1 188527632 6297548 828660..829418 1 NC_010698.2 COG3736 Type IV secretory pathway, component VirB8; cag pathogenicity island protein CagV 829418 6297548 HPSH_04270 Helicobacter pylori Shi470 cag pathogenicity island protein CagV YP_001910319.1 828660 D 512562 CDS YP_001910320.1 188527633 6297547 829423..831030 1 NC_010698.2 cag pathogenicity island protein CagW 831030 6297547 HPSH_04275 Helicobacter pylori Shi470 cag pathogenicity island protein CagW YP_001910320.1 829423 D 512562 CDS YP_001910321.1 188527634 6297546 831082..832650 1 NC_010698.2 COG3504 Type IV secretory pathway, VirB9 components; cag pathogenicity island protein CagX 832650 6297546 HPSH_04280 Helicobacter pylori Shi470 cag pathogenicity island protein CagX YP_001910321.1 831082 D 512562 CDS YP_001910322.1 188527635 6297545 832665..838229 1 NC_010698.2 COG2948 Type IV secretory pathway, VirB10 components; cag pathogenicity island protein CagY 838229 6297545 HPSH_04285 Helicobacter pylori Shi470 cag pathogenicity island protein CagY YP_001910322.1 832665 D 512562 CDS YP_001910323.1 188527636 6297544 838219..838353 1 NC_010698.2 hypothetical protein 838353 6297544 HPSH_04290 Helicobacter pylori Shi470 hypothetical protein YP_001910323.1 838219 D 512562 CDS YP_001910324.1 188527637 6296021 838366..838965 1 NC_010698.2 cag pathogenicity island protein CagZ 838965 6296021 HPSH_04295 Helicobacter pylori Shi470 cag pathogenicity island protein CagZ YP_001910324.1 838366 D 512562 CDS YP_001910325.1 188527638 6297539 838970..839962 1 NC_010698.2 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; cag pathogenicity island protein cag alpha 839962 6297539 HPSH_04300 Helicobacter pylori Shi470 cag pathogenicity island protein cag alpha YP_001910325.1 838970 D 512562 CDS YP_001910326.1 188527639 6297538 839971..842217 1 NC_010698.2 COG3505 Type IV secretory pathway, VirD4 components; cag pathogenicity island protein Cag beta 842217 6297538 HPSH_04305 Helicobacter pylori Shi470 cag pathogenicity island protein Cag beta YP_001910326.1 839971 D 512562 CDS YP_001910327.1 188527640 6297537 complement(842336..842716) 1 NC_010698.2 cag pathogenicity island protein Cag gamma 842716 6297537 HPSH_04310 Helicobacter pylori Shi470 cag pathogenicity island protein Cag gamma YP_001910327.1 842336 R 512562 CDS YP_001910328.1 188527641 6297536 complement(842855..844300) 1 NC_010698.2 cag pathogenicity island protein Cag delta 844300 6297536 HPSH_04315 Helicobacter pylori Shi470 cag pathogenicity island protein Cag delta YP_001910328.1 842855 R 512562 CDS YP_001910329.1 188527642 6297535 complement(844314..844511) 1 NC_010698.2 cag pathogenicity island protein Cag theta 844511 6297535 HPSH_04320 Helicobacter pylori Shi470 cag pathogenicity island protein Cag theta YP_001910329.1 844314 R 512562 CDS YP_001910330.1 188527643 6297533 complement(844527..844874) 1 NC_010698.2 cag pathogenicity island protein Cag zeta 844874 6297533 HPSH_04325 Helicobacter pylori Shi470 cag pathogenicity island protein Cag zeta YP_001910330.1 844527 R 512562 CDS YP_001910331.1 188527644 6297531 845087..845917 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 845917 6297531 HPSH_04330 Helicobacter pylori Shi470 hypothetical protein YP_001910331.1 845087 D 512562 CDS YP_001910332.1 188527645 6297530 complement(845992..846984) 1 NC_010698.2 COG3034 Uncharacterized protein conserved in bacteria; hypothetical protein 846984 6297530 HPSH_04335 Helicobacter pylori Shi470 hypothetical protein YP_001910332.1 845992 R 512562 CDS YP_001910333.1 188527646 6297529 complement(846981..847886) 1 NC_010698.2 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 847886 era 6297529 era Helicobacter pylori Shi470 GTP-binding protein Era YP_001910333.1 846981 R 512562 CDS YP_001910334.1 188527647 6297528 complement(847886..849217) 1 NC_010698.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 849217 hslU 6297528 hslU Helicobacter pylori Shi470 ATP-dependent protease ATP-binding subunit HslU YP_001910334.1 847886 R 512562 CDS YP_001910335.1 188527648 6297526 complement(849217..849759) 1 NC_010698.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 849759 6297526 HPSH_04350 Helicobacter pylori Shi470 ATP-dependent protease peptidase subunit YP_001910335.1 849217 R 512562 CDS YP_001910336.1 188527649 6297525 complement(849763..850212) 1 NC_010698.2 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 850212 rplI 6297525 rplI Helicobacter pylori Shi470 50S ribosomal protein L9 YP_001910336.1 849763 R 512562 CDS YP_001910337.1 188527650 6297524 complement(850275..852344) 1 NC_010698.2 COG1479 Uncharacterized conserved protein; hypothetical protein 852344 6297524 HPSH_04360 Helicobacter pylori Shi470 hypothetical protein YP_001910337.1 850275 R 512562 CDS YP_001910338.1 188527651 6297523 852479..853924 1 NC_010698.2 COG0174 Glutamine synthetase; glutamine synthetase 853924 6297523 HPSH_04365 Helicobacter pylori Shi470 glutamine synthetase YP_001910338.1 852479 D 512562 CDS YP_001910339.1 188527652 6297522 complement(854202..854282) 1 NC_010698.2 hypothetical protein 854282 6297522 HPSH_04370 Helicobacter pylori Shi470 hypothetical protein YP_001910339.1 854202 R 512562 CDS YP_001910340.1 188527653 6297521 complement(854616..855380) 1 NC_010698.2 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 855380 6297521 HPSH_04375 Helicobacter pylori Shi470 dihydrodipicolinate reductase YP_001910340.1 854616 R 512562 CDS YP_001910341.1 188527654 6297520 complement(855403..856782) 1 NC_010698.2 COG0277 FAD/FMN-containing dehydrogenases; putative glycolate oxidase 856782 6297520 HPSH_04380 Helicobacter pylori Shi470 putative glycolate oxidase YP_001910341.1 855403 R 512562 CDS YP_001910342.1 188527655 6297519 complement(856784..858091) 1 NC_010698.2 plasminogen binding protein 858091 6297519 HPSH_04385 Helicobacter pylori Shi470 plasminogen binding protein YP_001910342.1 856784 R 512562 CDS YP_001910343.1 188527656 6297518 complement(858102..858740) 1 NC_010698.2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; hypothetical protein 858740 6297518 HPSH_04390 Helicobacter pylori Shi470 hypothetical protein YP_001910343.1 858102 R 512562 CDS YP_001910344.1 188527657 6297338 complement(858740..859948) 1 NC_010698.2 COG0739 Membrane proteins related to metalloendopeptidases; putative outer membrane protein 859948 6297338 HPSH_04395 Helicobacter pylori Shi470 putative outer membrane protein YP_001910344.1 858740 R 512562 CDS YP_001910345.1 188527658 6297542 860422..860805 1 NC_010698.2 hypothetical protein 860805 6297542 HPSH_04400 Helicobacter pylori Shi470 hypothetical protein YP_001910345.1 860422 D 512562 CDS YP_001910346.1 188527659 6297241 complement(860819..860893) 1 NC_010698.2 hypothetical protein 860893 6297241 HPSH_04405 Helicobacter pylori Shi470 hypothetical protein YP_001910346.1 860819 R 512562 CDS YP_001910347.1 188527660 6297516 complement(860900..863221) 1 NC_010698.2 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 863221 gyrB 6297516 gyrB Helicobacter pylori Shi470 DNA gyrase subunit B YP_001910347.1 860900 R 512562 CDS YP_001910348.1 188527661 6297515 complement(863233..864357) 1 NC_010698.2 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 864357 6297515 HPSH_04415 Helicobacter pylori Shi470 DNA polymerase III subunit beta YP_001910348.1 863233 R 512562 CDS YP_001910349.1 188527662 6297514 complement(864415..865482) 1 NC_010698.2 COG2829 Outer membrane phospholipase A; phospholipase A1 865482 6297514 HPSH_04420 Helicobacter pylori Shi470 phospholipase A1 YP_001910349.1 864415 R 512562 CDS YP_001910350.1 188527663 6297513 complement(865497..866825) 1 NC_010698.2 COG0733 Na+-dependent transporters of the SNF family; sodium- and chloride-dependent transporter 866825 6297513 HPSH_04425 Helicobacter pylori Shi470 sodium- and chloride-dependent transporter YP_001910350.1 865497 R 512562 CDS YP_001910351.1 188527664 6297512 complement(866836..868164) 1 NC_010698.2 COG0733 Na+-dependent transporters of the SNF family; sodium- and chloride-dependent transporter 868164 6297512 HPSH_04430 Helicobacter pylori Shi470 sodium- and chloride-dependent transporter YP_001910351.1 866836 R 512562 CDS YP_001910352.1 188527665 6297511 868394..868795 1 NC_010698.2 COG0824 Predicted thioesterase; hypothetical protein 868795 6297511 HPSH_04435 Helicobacter pylori Shi470 hypothetical protein YP_001910352.1 868394 D 512562 CDS YP_001910353.1 188527666 6297510 868785..869045 1 NC_010698.2 hypothetical protein 869045 6297510 HPSH_04440 Helicobacter pylori Shi470 hypothetical protein YP_001910353.1 868785 D 512562 CDS YP_001910354.1 188527667 6297508 complement(869042..870310) 1 NC_010698.2 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 870310 murD 6297508 murD Helicobacter pylori Shi470 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001910354.1 869042 R 512562 CDS YP_001910355.1 188527668 6297507 complement(870312..871373) 1 NC_010698.2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 871373 mraY 6297507 mraY Helicobacter pylori Shi470 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001910355.1 870312 R 512562 CDS YP_001910356.1 188527669 6297506 871498..872340 1 NC_010698.2 hypothetical protein 872340 6297506 HPSH_04455 Helicobacter pylori Shi470 hypothetical protein YP_001910356.1 871498 D 512562 CDS YP_001910357.1 188527670 6297504 872440..872628 1 NC_010698.2 required for 70S ribosome assembly; 50S ribosomal protein L28 872628 rpmB 6297504 rpmB Helicobacter pylori Shi470 50S ribosomal protein L28 YP_001910357.1 872440 D 512562 CDS YP_001910358.1 188527671 6297503 872778..873914 1 NC_010698.2 COG1226 Kef-type K+ transport systems, predicted NAD-binding component; putative potassium channel protein 873914 6297503 HPSH_04465 Helicobacter pylori Shi470 putative potassium channel protein YP_001910358.1 872778 D 512562 CDS YP_001910359.1 188527672 6297502 complement(873916..874311) 1 NC_010698.2 COG0467 RecA-superfamily ATPases implicated in signal transduction; hypothetical protein 874311 6297502 HPSH_04470 Helicobacter pylori Shi470 hypothetical protein YP_001910359.1 873916 R 512562 CDS YP_001910360.1 188527673 6297501 complement(874327..874701) 1 NC_010698.2 hypothetical protein 874701 6297501 HPSH_04475 Helicobacter pylori Shi470 hypothetical protein YP_001910360.1 874327 R 512562 CDS YP_001910361.1 188527674 6296932 874998..876074 1 NC_010698.2 COG0582 Integrase; integrase/recombinase XerD 876074 6296932 HPSH_04480 Helicobacter pylori Shi470 integrase/recombinase XerD YP_001910361.1 874998 D 512562 CDS YP_001910362.1 188527675 6297498 complement(876139..877341) 1 NC_010698.2 hypothetical protein 877341 6297498 HPSH_04485 Helicobacter pylori Shi470 hypothetical protein YP_001910362.1 876139 R 512562 CDS YP_001910363.1 188527676 6297497 complement(877341..878726) 1 NC_010698.2 hypothetical protein 878726 6297497 HPSH_04490 Helicobacter pylori Shi470 hypothetical protein YP_001910363.1 877341 R 512562 CDS YP_001910364.1 188527677 6297496 complement(878730..880871) 1 NC_010698.2 hypothetical protein 880871 6297496 HPSH_04495 Helicobacter pylori Shi470 hypothetical protein YP_001910364.1 878730 R 512562 CDS YP_001910365.1 188527678 6297495 complement(880915..882183) 1 NC_010698.2 hypothetical protein 882183 6297495 HPSH_04500 Helicobacter pylori Shi470 hypothetical protein YP_001910365.1 880915 R 512562 CDS YP_001910366.1 188527679 6297494 complement(882184..883221) 1 NC_010698.2 hypothetical protein 883221 6297494 HPSH_04505 Helicobacter pylori Shi470 hypothetical protein YP_001910366.1 882184 R 512562 CDS YP_001910367.1 188527680 6297493 883375..891786 1 NC_010698.2 COG0827 Adenine-specific DNA methylase; hypothetical protein 891786 6297493 HPSH_04510 Helicobacter pylori Shi470 hypothetical protein YP_001910367.1 883375 D 512562 CDS YP_001910368.1 188527681 6297492 892053..892709 1 NC_010698.2 COG1192 ATPases involved in chromosome partitioning; PARA protein 892709 6297492 HPSH_04515 Helicobacter pylori Shi470 PARA protein YP_001910368.1 892053 D 512562 CDS YP_001910369.1 188527682 6297490 892794..893063 1 NC_010698.2 hypothetical protein 893063 6297490 HPSH_04520 Helicobacter pylori Shi470 hypothetical protein YP_001910369.1 892794 D 512562 CDS YP_001910370.1 188527683 6297489 893095..894273 1 NC_010698.2 hypothetical protein 894273 6297489 HPSH_04525 Helicobacter pylori Shi470 hypothetical protein YP_001910370.1 893095 D 512562 CDS YP_001910371.1 188527684 6297488 complement(894298..896205) 1 NC_010698.2 COG3843 Type IV secretory pathway, VirD2 components (relaxase); hypothetical protein 896205 6297488 HPSH_04530 Helicobacter pylori Shi470 hypothetical protein YP_001910371.1 894298 R 512562 CDS YP_001910372.1 188527685 6297486 896499..896813 1 NC_010698.2 hypothetical protein 896813 6297486 HPSH_04535 Helicobacter pylori Shi470 hypothetical protein YP_001910372.1 896499 D 512562 CDS YP_001910373.1 188527686 6297485 896806..897087 1 NC_010698.2 COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein 897087 6297485 HPSH_04540 Helicobacter pylori Shi470 hypothetical protein YP_001910373.1 896806 D 512562 CDS YP_001910374.1 188527687 6297483 complement(897362..899089) 1 NC_010698.2 COG3505 Type IV secretory pathway, VirD4 components; conjugal transfer protein TraG 899089 6297483 HPSH_04545 Helicobacter pylori Shi470 conjugal transfer protein TraG YP_001910374.1 897362 R 512562 CDS YP_001910375.1 188527688 6297482 complement(899090..899647) 1 NC_010698.2 hypothetical protein 899647 6297482 HPSH_04550 Helicobacter pylori Shi470 hypothetical protein YP_001910375.1 899090 R 512562 CDS YP_001910376.1 188527689 6297481 complement(899648..899938) 1 NC_010698.2 hypothetical protein 899938 6297481 HPSH_04555 Helicobacter pylori Shi470 hypothetical protein YP_001910376.1 899648 R 512562 CDS YP_001910377.1 188527690 6297480 complement(899935..900390) 1 NC_010698.2 hypothetical protein 900390 6297480 HPSH_04560 Helicobacter pylori Shi470 hypothetical protein YP_001910377.1 899935 R 512562 CDS YP_001910378.1 188527691 6297479 complement(900387..901328) 1 NC_010698.2 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; VirB11 type IV secretion ATPase 901328 6297479 HPSH_04565 Helicobacter pylori Shi470 VirB11 type IV secretion ATPase YP_001910378.1 900387 R 512562 CDS YP_001910379.1 188527692 6297476 complement(901328..901627) 1 NC_010698.2 hypothetical protein 901627 6297476 HPSH_04570 Helicobacter pylori Shi470 hypothetical protein YP_001910379.1 901328 R 512562 CDS YP_001910380.1 188527693 6297475 complement(901624..901887) 1 NC_010698.2 hypothetical protein 901887 6297475 HPSH_04575 Helicobacter pylori Shi470 hypothetical protein YP_001910380.1 901624 R 512562 CDS YP_001910381.1 188527694 6297420 complement(902009..902173) 1 NC_010698.2 hypothetical protein 902173 6297420 HPSH_04580 Helicobacter pylori Shi470 hypothetical protein YP_001910381.1 902009 R 512562 CDS YP_001910382.1 188527695 6297072 complement(902170..902256) 1 NC_010698.2 hypothetical protein 902256 6297072 HPSH_04585 Helicobacter pylori Shi470 hypothetical protein YP_001910382.1 902170 R 512562 CDS YP_001910383.1 188527696 6296639 complement(902243..903478) 1 NC_010698.2 COG2948 Type IV secretory pathway, VirB10 components; ComB3 protein 903478 6296639 HPSH_04590 Helicobacter pylori Shi470 ComB3 protein YP_001910383.1 902243 R 512562 CDS YP_001910384.1 188527697 6297473 complement(903475..905016) 1 NC_010698.2 COG3504 Type IV secretory pathway, VirB9 components; conjugal plasmid transfer system protein 905016 6297473 HPSH_04595 Helicobacter pylori Shi470 conjugal plasmid transfer system protein YP_001910384.1 903475 R 512562 CDS YP_001910385.1 188527698 6297472 complement(905016..906002) 1 NC_010698.2 COG3736 Type IV secretory pathway, component VirB8; hypothetical protein 906002 6297472 HPSH_04600 Helicobacter pylori Shi470 hypothetical protein YP_001910385.1 905016 R 512562 CDS YP_001910386.1 188527699 6297471 complement(906004..906132) 1 NC_010698.2 hypothetical protein 906132 6297471 HPSH_04605 Helicobacter pylori Shi470 hypothetical protein YP_001910386.1 906004 R 512562 CDS YP_001910387.1 188527700 6297470 complement(906132..908066) 1 NC_010698.2 COG0550 Topoisomerase IA; topoisomerase I 908066 6297470 HPSH_04610 Helicobacter pylori Shi470 topoisomerase I YP_001910387.1 906132 R 512562 CDS YP_001910388.1 188527701 6297469 complement(908059..910557) 1 NC_010698.2 COG3451 Type IV secretory pathway, VirB4 components; DNA transfer protein 910557 6297469 HPSH_04615 Helicobacter pylori Shi470 DNA transfer protein YP_001910388.1 908059 R 512562 CDS YP_001910389.1 188527702 6297468 complement(910570..910830) 1 NC_010698.2 hypothetical protein 910830 6297468 HPSH_04620 Helicobacter pylori Shi470 hypothetical protein YP_001910389.1 910570 R 512562 CDS YP_001910390.1 188527703 6297467 complement(910831..911133) 1 NC_010698.2 hypothetical protein 911133 6297467 HPSH_04625 Helicobacter pylori Shi470 hypothetical protein YP_001910390.1 910831 R 512562 CDS YP_001910391.1 188527704 6297466 complement(911123..911593) 1 NC_010698.2 hypothetical protein 911593 6297466 HPSH_04630 Helicobacter pylori Shi470 hypothetical protein YP_001910391.1 911123 R 512562 CDS YP_001910392.1 188527705 6297464 complement(911758..913038) 1 NC_010698.2 hypothetical protein 913038 6297464 HPSH_04635 Helicobacter pylori Shi470 hypothetical protein YP_001910392.1 911758 R 512562 CDS YP_001910393.1 188527706 6297463 complement(913049..913813) 1 NC_010698.2 hypothetical protein 913813 6297463 HPSH_04640 Helicobacter pylori Shi470 hypothetical protein YP_001910393.1 913049 R 512562 CDS YP_001910394.1 188527707 6297462 complement(913835..915454) 1 NC_010698.2 hypothetical protein 915454 6297462 HPSH_04645 Helicobacter pylori Shi470 hypothetical protein YP_001910394.1 913835 R 512562 CDS YP_001910395.1 188527708 6297461 915459..915701 1 NC_010698.2 hypothetical protein 915701 6297461 HPSH_04650 Helicobacter pylori Shi470 hypothetical protein YP_001910395.1 915459 D 512562 CDS YP_001910396.1 188527709 6297460 complement(915726..916277) 1 NC_010698.2 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 916277 ruvA 6297460 ruvA Helicobacter pylori Shi470 Holliday junction DNA helicase RuvA YP_001910396.1 915726 R 512562 CDS YP_001910397.1 188527710 6297556 complement(916302..918146) 1 NC_010698.2 hypothetical protein 918146 6297556 HPSH_04660 Helicobacter pylori Shi470 hypothetical protein YP_001910397.1 916302 R 512562 CDS YP_001910398.1 188527711 6297456 918239..919699 1 NC_010698.2 COG0728 Uncharacterized membrane protein, putative virulence factor; virulence factor MviN 919699 6297456 HPSH_04665 Helicobacter pylori Shi470 virulence factor MviN YP_001910398.1 918239 D 512562 CDS YP_001910399.1 188527712 6297455 919700..921097 1 NC_010698.2 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 921097 cysS 6297455 cysS Helicobacter pylori Shi470 cysteinyl-tRNA synthetase YP_001910399.1 919700 D 512562 CDS YP_001910400.1 188527713 6297454 921330..925193 1 NC_010698.2 vacuolating cytotoxin A 925193 6297454 HPSH_04675 Helicobacter pylori Shi470 vacuolating cytotoxin A YP_001910400.1 921330 D 512562 CDS YP_001910401.1 188527714 6297453 complement(925190..925345) 1 NC_010698.2 hypothetical protein 925345 6297453 HPSH_04680 Helicobacter pylori Shi470 hypothetical protein YP_001910401.1 925190 R 512562 CDS YP_001910402.1 188527715 6297452 complement(925497..926264) 1 NC_010698.2 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; iron(III) dicitrate transporter, ATP-binding protein 926264 6297452 HPSH_04685 Helicobacter pylori Shi470 iron(III) dicitrate transporter, ATP-binding protein YP_001910402.1 925497 R 512562 CDS YP_001910403.1 188527716 6297451 complement(926264..927244) 1 NC_010698.2 COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron(III dicitrate ABC transporter permease FecD 927244 6297451 HPSH_04690 Helicobacter pylori Shi470 iron(III dicitrate ABC transporter permease FecD YP_001910403.1 926264 R 512562 CDS YP_001910404.1 188527717 6297450 complement(927237..928079) 1 NC_010698.2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain oxidoreductase 928079 6297450 HPSH_04695 Helicobacter pylori Shi470 short-chain oxidoreductase YP_001910404.1 927237 R 512562 CDS YP_001910405.1 188527718 6297449 928220..928744 1 NC_010698.2 COG1607 Acyl-CoA hydrolase; hypothetical protein 928744 6297449 HPSH_04700 Helicobacter pylori Shi470 hypothetical protein YP_001910405.1 928220 D 512562 CDS YP_001910406.1 188527719 6297448 complement(928847..929113) 1 NC_010698.2 COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein 929113 6297448 HPSH_04705 Helicobacter pylori Shi470 hypothetical protein YP_001910406.1 928847 R 512562 CDS YP_001910407.1 188527720 6297447 complement(929094..929471) 1 NC_010698.2 hypothetical protein 929471 6297447 HPSH_04710 Helicobacter pylori Shi470 hypothetical protein YP_001910407.1 929094 R 512562 CDS YP_001910408.1 188527721 6297446 complement(929531..929695) 1 NC_010698.2 hypothetical protein 929695 6297446 HPSH_04715 Helicobacter pylori Shi470 hypothetical protein YP_001910408.1 929531 R 512562 CDS YP_001910409.1 188527722 6297444 complement(929699..931930) 1 NC_010698.2 outer membrane protein BabA 931930 6297444 HPSH_04720 Helicobacter pylori Shi470 outer membrane protein BabA YP_001910409.1 929699 R 512562 CDS YP_001910410.1 188527723 6297443 931997..932125 1 NC_010698.2 hypothetical protein 932125 6297443 HPSH_04725 Helicobacter pylori Shi470 hypothetical protein YP_001910410.1 931997 D 512562 CDS YP_001910411.1 188527724 6297440 complement(932848..933960) 1 NC_010698.2 COG0409 Hydrogenase maturation factor; hydrogenase expression/formation protein HypD 933960 6297440 HPSH_04735 Helicobacter pylori Shi470 hydrogenase expression/formation protein HypD YP_001910411.1 932848 R 512562 CDS YP_001910412.1 188527725 6297437 complement(933979..934215) 1 NC_010698.2 COG0298 Hydrogenase maturation factor; hydrogenase expression/formation protein HypC 934215 6297437 HPSH_04740 Helicobacter pylori Shi470 hydrogenase expression/formation protein HypC YP_001910412.1 933979 R 512562 CDS YP_001910413.1 188527726 6297294 complement(934215..934943) 1 NC_010698.2 COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; hydrogenase expression/formation protein HypB 934943 6297294 HPSH_04745 Helicobacter pylori Shi470 hydrogenase expression/formation protein HypB YP_001910413.1 934215 R 512562 CDS YP_001910414.1 188527727 6297499 complement(934960..935064) 1 NC_010698.2 hypothetical protein 935064 6297499 HPSH_04750 Helicobacter pylori Shi470 hypothetical protein YP_001910414.1 934960 R 512562 CDS YP_001910415.1 188527728 6296371 complement(935204..935503) 1 NC_010698.2 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 935503 6296371 HPSH_04755 Helicobacter pylori Shi470 hypothetical protein YP_001910415.1 935204 R 512562 CDS YP_001910416.1 188527729 6297435 complement(935514..936719) 1 NC_010698.2 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 936719 6297435 HPSH_04760 Helicobacter pylori Shi470 acetate kinase YP_001910416.1 935514 R 512562 CDS YP_001910417.1 188527730 6297434 complement(936737..938293) 1 NC_010698.2 COG0280 Phosphotransacetylase; phosphotransacetylase 938293 6297434 HPSH_04765 Helicobacter pylori Shi470 phosphotransacetylase YP_001910417.1 936737 R 512562 CDS YP_001910418.1 188527731 6297433 938515..940074 1 NC_010698.2 hypothetical protein 940074 6297433 HPSH_04770 Helicobacter pylori Shi470 hypothetical protein YP_001910418.1 938515 D 512562 CDS YP_001910419.1 188527732 6297432 940125..941099 1 NC_010698.2 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 941099 flgD 6297432 flgD Helicobacter pylori Shi470 flagellar basal body rod modification protein YP_001910419.1 940125 D 512562 CDS YP_001910420.1 188527733 6297431 941096..942913 1 NC_010698.2 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 942913 flgE 6297431 flgE Helicobacter pylori Shi470 flagellar hook protein FlgE YP_001910420.1 941096 D 512562 CDS YP_001910421.1 188527734 6297430 942972..943607 1 NC_010698.2 putative restriction endonuclease 943607 6297430 HPSH_04785 Helicobacter pylori Shi470 putative restriction endonuclease YP_001910421.1 942972 D 512562 CDS YP_001910422.1 188527735 6297429 943588..944736 1 NC_010698.2 COG0827 Adenine-specific DNA methylase; type II DNA modification methyltransferase 944736 6297429 HPSH_04790 Helicobacter pylori Shi470 type II DNA modification methyltransferase YP_001910422.1 943588 D 512562 CDS YP_001910423.1 188527736 6297428 944730..946760 1 NC_010698.2 COG0210 Superfamily I DNA and RNA helicases; rep helicase, single-stranded DNA-dependent ATPase 946760 6297428 HPSH_04795 Helicobacter pylori Shi470 rep helicase, single-stranded DNA-dependent ATPase YP_001910423.1 944730 D 512562 CDS YP_001910424.1 188527737 6297427 947076..947177 1 NC_010698.2 hypothetical protein 947177 6297427 HPSH_04800 Helicobacter pylori Shi470 hypothetical protein YP_001910424.1 947076 D 512562 CDS YP_001910425.1 188527738 6297425 947287..948855 1 NC_010698.2 outer membrane protein HopC 948855 6297425 HPSH_04805 Helicobacter pylori Shi470 outer membrane protein HopC YP_001910425.1 947287 D 512562 CDS YP_001910426.1 188527739 6297424 948877..950457 1 NC_010698.2 outer membrane protein HopB 950457 6297424 HPSH_04810 Helicobacter pylori Shi470 outer membrane protein HopB YP_001910426.1 948877 D 512562 CDS YP_001910427.1 188527740 6297423 complement(950601..950672) 1 NC_010698.2 hypothetical protein 950672 6297423 HPSH_04815 Helicobacter pylori Shi470 hypothetical protein YP_001910427.1 950601 R 512562 CDS YP_001910428.1 188527741 6297422 complement(952775..955216) 1 NC_010698.2 COG1629 Outer membrane receptor proteins, mostly Fe transport; iron-regulated outer membrane protein 955216 6297422 HPSH_04830 Helicobacter pylori Shi470 iron-regulated outer membrane protein YP_001910428.1 952775 R 512562 CDS YP_001910429.1 188527742 6297421 complement(955391..955822) 1 NC_010698.2 hypothetical protein 955822 6297421 HPSH_04835 Helicobacter pylori Shi470 hypothetical protein YP_001910429.1 955391 R 512562 CDS YP_001910430.1 188527743 6297474 complement(955827..959084) 1 NC_010698.2 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 959084 carB 6297474 carB Helicobacter pylori Shi470 carbamoyl phosphate synthase large subunit YP_001910430.1 955827 R 512562 CDS YP_001910431.1 188527744 6297417 complement(959179..959871) 1 NC_010698.2 COG0670 Integral membrane protein, interacts with FtsH; hypothetical protein 959871 6297417 HPSH_04845 Helicobacter pylori Shi470 hypothetical protein YP_001910431.1 959179 R 512562 CDS YP_001910432.1 188527745 6297416 960014..961009 1 NC_010698.2 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 961009 6297416 HPSH_04850 Helicobacter pylori Shi470 glyceraldehyde-3-phosphate dehydrogenase YP_001910432.1 960014 D 512562 CDS YP_001910433.1 188527746 6297415 968318..969421 1 NC_010698.2 outer membrane protein 969421 6297415 HPSH_04865 Helicobacter pylori Shi470 outer membrane protein YP_001910433.1 968318 D 512562 CDS YP_001910434.1 188527747 6297414 complement(969478..969684) 1 NC_010698.2 COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; 4-oxalocrotonate tautomerase 969684 6297414 HPSH_04870 Helicobacter pylori Shi470 4-oxalocrotonate tautomerase YP_001910434.1 969478 R 512562 CDS YP_001910435.1 188527748 6297413 969830..970411 1 NC_010698.2 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 970411 recR 6297413 recR Helicobacter pylori Shi470 recombination protein RecR YP_001910435.1 969830 D 512562 CDS YP_001910436.1 188527749 6297412 970408..971553 1 NC_010698.2 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 971553 truD 6297412 truD Helicobacter pylori Shi470 tRNA pseudouridine synthase D YP_001910436.1 970408 D 512562 CDS YP_001910437.1 188527750 6297411 971540..972472 1 NC_010698.2 putative metalloprotease; heat shock protein HtpX 972472 6297411 HPSH_04885 Helicobacter pylori Shi470 heat shock protein HtpX YP_001910437.1 971540 D 512562 CDS YP_001910438.1 188527751 6297410 972473..973015 1 NC_010698.2 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 973015 folE 6297410 folE Helicobacter pylori Shi470 GTP cyclohydrolase I YP_001910438.1 972473 D 512562 CDS YP_001910439.1 188527752 6297408 973031..973942 1 NC_010698.2 COG0142 Geranylgeranyl pyrophosphate synthase; geranyltranstransferase 973942 6297408 HPSH_04895 Helicobacter pylori Shi470 geranyltranstransferase YP_001910439.1 973031 D 512562 CDS YP_001910440.1 188527753 6297407 973939..974742 1 NC_010698.2 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 974742 surE 6297407 surE Helicobacter pylori Shi470 stationary phase survival protein SurE YP_001910440.1 973939 D 512562 CDS YP_001910441.1 188527754 6297406 974739..975398 1 NC_010698.2 hypothetical protein 975398 6297406 HPSH_04905 Helicobacter pylori Shi470 hypothetical protein YP_001910441.1 974739 D 512562 CDS YP_001910442.1 188527755 6297403 975402..976004 1 NC_010698.2 COG0720 6-pyruvoyl-tetrahydropterin synthase; hypothetical protein 976004 6297403 HPSH_04910 Helicobacter pylori Shi470 hypothetical protein YP_001910442.1 975402 D 512562 CDS YP_001910443.1 188527756 6297402 976001..976756 1 NC_010698.2 COG0602 Organic radical activating enzymes; hypothetical protein 976756 6297402 HPSH_04915 Helicobacter pylori Shi470 hypothetical protein YP_001910443.1 976001 D 512562 CDS YP_001910444.1 188527757 6297401 976767..977252 1 NC_010698.2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 977252 6297401 HPSH_04920 Helicobacter pylori Shi470 hypothetical protein YP_001910444.1 976767 D 512562 CDS YP_001910445.1 188527758 6297400 977473..979458 1 NC_010698.2 putative outer membrane protein HomB 979458 6297400 HPSH_04925 Helicobacter pylori Shi470 putative outer membrane protein HomB YP_001910445.1 977473 D 512562 CDS YP_001910446.1 188527759 6297399 complement(979596..980765) 1 NC_010698.2 COG0477 Permeases of the major facilitator superfamily; proline and betaine transporter 980765 6297399 HPSH_04930 Helicobacter pylori Shi470 proline and betaine transporter YP_001910446.1 979596 R 512562 CDS YP_001910447.1 188527760 6297398 complement(981198..981407) 1 NC_010698.2 COG1479 Uncharacterized conserved protein; hypothetical protein 981407 6297398 HPSH_04935 Helicobacter pylori Shi470 hypothetical protein YP_001910447.1 981198 R 512562 CDS YP_001910448.1 188527761 6297397 complement(981475..982197) 1 NC_010698.2 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 982197 6297397 HPSH_04940 Helicobacter pylori Shi470 amino acid ABC transporter permease YP_001910448.1 981475 R 512562 CDS YP_001910449.1 188527762 6297381 complement(982172..982948) 1 NC_010698.2 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; polar amino acid ABC transporter periplasmic protein 982948 6297381 HPSH_04945 Helicobacter pylori Shi470 polar amino acid ABC transporter periplasmic protein YP_001910449.1 982172 R 512562 CDS YP_001910451.1 188527764 6296338 complement(983017..984150) 1 NC_010698.2 COG0787 Alanine racemase; alanine racemase 984150 6296338 HPSH_04955 Helicobacter pylori Shi470 alanine racemase YP_001910451.1 983017 R 512562 CDS YP_001910452.1 188527765 6297395 complement(984157..985509) 1 NC_010698.2 COG1115 Na+/alanine symporter; D-alanine glycine permease 985509 6297395 HPSH_04960 Helicobacter pylori Shi470 D-alanine glycine permease YP_001910452.1 984157 R 512562 CDS YP_001910453.1 188527766 6297394 complement(985550..986782) 1 NC_010698.2 COG0665 Glycine/D-amino acid oxidases (deaminating); D-Amino acid dehydrogenase 986782 6297394 HPSH_04965 Helicobacter pylori Shi470 D-Amino acid dehydrogenase YP_001910453.1 985550 R 512562 CDS YP_001910454.1 188527767 6297392 complement(986805..987182) 1 NC_010698.2 COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 987182 6297392 HPSH_04970 Helicobacter pylori Shi470 hypothetical protein YP_001910454.1 986805 R 512562 CDS YP_001910455.1 188527768 6297390 complement(987594..987890) 1 NC_010698.2 hypothetical protein 987890 6297390 HPSH_04975 Helicobacter pylori Shi470 hypothetical protein YP_001910455.1 987594 R 512562 CDS YP_001910456.1 188527769 6297385 990240..990635 1 NC_010698.2 hypothetical protein 990635 6297385 HPSH_04990 Helicobacter pylori Shi470 hypothetical protein YP_001910456.1 990240 D 512562 CDS YP_001910457.1 188527770 6297383 complement(991213..992226) 1 NC_010698.2 hypothetical protein 992226 6297383 HPSH_04995 Helicobacter pylori Shi470 hypothetical protein YP_001910457.1 991213 R 512562 CDS YP_001910458.1 188527771 6297396 complement(992236..992688) 1 NC_010698.2 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 992688 6297396 HPSH_05000 Helicobacter pylori Shi470 rRNA large subunit methyltransferase YP_001910458.1 992236 R 512562 CDS YP_001910459.1 188527772 6297379 complement(992702..993571) 1 NC_010698.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 993571 6297379 HPSH_05005 Helicobacter pylori Shi470 acetyl-CoA carboxylase subunit beta YP_001910459.1 992702 R 512562 CDS YP_001910460.1 188527773 6297378 993652..994266 1 NC_010698.2 COG0540 Aspartate carbamoyltransferase, catalytic chain; putative recombination protein RecO 994266 6297378 HPSH_05010 Helicobacter pylori Shi470 putative recombination protein RecO YP_001910460.1 993652 D 512562 CDS YP_001910461.1 188527774 6297377 994277..994933 1 NC_010698.2 COG1546 Uncharacterized protein (competence- and mitomycin-induced); hypothetical protein 994933 6297377 HPSH_05015 Helicobacter pylori Shi470 hypothetical protein YP_001910461.1 994277 D 512562 CDS YP_001910462.1 188527775 6297376 complement(994936..995502) 1 NC_010698.2 hypothetical protein 995502 6297376 HPSH_05020 Helicobacter pylori Shi470 hypothetical protein YP_001910462.1 994936 R 512562 CDS YP_001910463.1 188527776 6297373 complement(996196..997050) 1 NC_010698.2 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 997050 6297373 HPSH_05035 Helicobacter pylori Shi470 prolipoprotein diacylglyceryl transferase YP_001910463.1 996196 R 512562 CDS YP_001910464.1 188527777 6297372 complement(997060..997788) 1 NC_010698.2 COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein 997788 6297372 HPSH_05040 Helicobacter pylori Shi470 hypothetical protein YP_001910464.1 997060 R 512562 CDS YP_001910465.1 188527778 6297371 complement(997806..998987) 1 NC_010698.2 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 998987 6297371 HPSH_05045 Helicobacter pylori Shi470 3-deoxy-D-manno-octulosonic-acid transferase YP_001910465.1 997806 R 512562 CDS YP_001910466.1 188527779 6297369 complement(998988..999752) 1 NC_010698.2 COG1579 Zn-ribbon protein, possibly nucleic acid-binding; hypothetical protein 999752 6297369 HPSH_05050 Helicobacter pylori Shi470 hypothetical protein YP_001910466.1 998988 R 512562 CDS YP_001910467.1 188527780 6297368 complement(999762..1000493) 1 NC_010698.2 COG0327 Uncharacterized conserved protein; hypothetical protein 1000493 6297368 HPSH_05055 Helicobacter pylori Shi470 hypothetical protein YP_001910467.1 999762 R 512562 CDS YP_001910468.1 188527781 6297367 complement(1000495..1001391) 1 NC_010698.2 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1001391 glyQ 6297367 glyQ Helicobacter pylori Shi470 glycyl-tRNA synthetase subunit alpha YP_001910468.1 1000495 R 512562 CDS YP_001910469.1 188527782 6297365 complement(1001405..1002343) 1 NC_010698.2 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1002343 gpsA 6297365 gpsA Helicobacter pylori Shi470 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001910469.1 1001405 R 512562 CDS YP_001910470.1 188527783 6297364 complement(1002373..1002522) 1 NC_010698.2 hypothetical protein 1002522 6297364 HPSH_05070 Helicobacter pylori Shi470 hypothetical protein YP_001910470.1 1002373 R 512562 CDS YP_001910471.1 188527784 6297363 complement(1003750..1006050) 1 NC_010698.2 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 1006050 6297363 HPSH_05085 Helicobacter pylori Shi470 hypothetical protein YP_001910471.1 1003750 R 512562 CDS YP_001910472.1 188527785 6297362 complement(1007543..1007695) 1 NC_010698.2 hypothetical protein 1007695 6297362 HPSH_05105 Helicobacter pylori Shi470 hypothetical protein YP_001910472.1 1007543 R 512562 CDS YP_001910473.1 188527786 6297361 complement(1007902..1008189) 1 NC_010698.2 COG3309 Uncharacterized virulence-associated protein D; virulence associated protein D 1008189 6297361 HPSH_05110 Helicobacter pylori Shi470 virulence associated protein D YP_001910473.1 1007902 R 512562 CDS YP_001910474.1 188527787 6297360 complement(1008257..1008538) 1 NC_010698.2 hypothetical protein 1008538 6297360 HPSH_05115 Helicobacter pylori Shi470 hypothetical protein YP_001910474.1 1008257 R 512562 CDS YP_001910475.1 188527788 6297359 complement(1008549..1011608) 1 NC_010698.2 COG3696 Putative silver efflux pump; putative cation efflux system protein 1011608 6297359 HPSH_05120 Helicobacter pylori Shi470 putative cation efflux system protein YP_001910475.1 1008549 R 512562 CDS YP_001910476.1 188527789 6297358 complement(1011608..1012687) 1 NC_010698.2 COG0845 Membrane-fusion protein; cobalt-zinc-cadmium resistance protein 1012687 6297358 HPSH_05125 Helicobacter pylori Shi470 cobalt-zinc-cadmium resistance protein YP_001910476.1 1011608 R 512562 CDS YP_001910477.1 188527790 6297357 complement(1012684..1014009) 1 NC_010698.2 hypothetical protein 1014009 6297357 HPSH_05130 Helicobacter pylori Shi470 hypothetical protein YP_001910477.1 1012684 R 512562 CDS YP_001910478.1 188527791 6297245 complement(1013981..1016083) 1 NC_010698.2 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1016083 glyS 6297245 glyS Helicobacter pylori Shi470 glycyl-tRNA synthetase subunit beta YP_001910478.1 1013981 R 512562 CDS YP_001910479.1 188527792 6297457 1016195..1017262 1 NC_010698.2 hypothetical protein 1017262 6297457 HPSH_05140 Helicobacter pylori Shi470 hypothetical protein YP_001910479.1 1016195 D 512562 CDS YP_001910480.1 188527793 6296423 1017275..1018750 1 NC_010698.2 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1018750 6296423 HPSH_05145 Helicobacter pylori Shi470 phosphoglyceromutase YP_001910480.1 1017275 D 512562 CDS YP_001910481.1 188527794 6297354 1018765..1019046 1 NC_010698.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1019046 gatC 6297354 gatC Helicobacter pylori Shi470 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_001910481.1 1018765 D 512562 CDS YP_001910482.1 188527795 6297353 complement(1019119..1020429) 1 NC_010698.2 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 1020429 6297353 HPSH_05155 Helicobacter pylori Shi470 adenosylmethionine--8-amino-7-oxononanoate transaminase YP_001910482.1 1019119 R 512562 CDS YP_001910483.1 188527796 6297352 1020469..1022022 1 NC_010698.2 COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein 1022022 6297352 HPSH_05160 Helicobacter pylori Shi470 hypothetical protein YP_001910483.1 1020469 D 512562 CDS YP_001910484.1 188527797 6297350 1022037..1023518 1 NC_010698.2 COG0849 Actin-like ATPase involved in cell division; cell division protein 1023518 6297350 HPSH_05165 Helicobacter pylori Shi470 cell division protein YP_001910484.1 1022037 D 512562 CDS YP_001910485.1 188527798 6297349 1023653..1024801 1 NC_010698.2 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1024801 6297349 HPSH_05170 Helicobacter pylori Shi470 cell division protein FtsZ YP_001910485.1 1023653 D 512562 CDS YP_001910486.1 188527799 6297348 complement(1024868..1024975) 1 NC_010698.2 hypothetical protein 1024975 6297348 HPSH_05175 Helicobacter pylori Shi470 hypothetical protein YP_001910486.1 1024868 R 512562 CDS YP_001910487.1 188527800 6297347 complement(1026463..1027287) 1 NC_010698.2 COG0668 Small-conductance mechanosensitive channel; hypothetical protein 1027287 6297347 HPSH_05200 Helicobacter pylori Shi470 hypothetical protein YP_001910487.1 1026463 R 512562 CDS YP_001910488.1 188527801 6297346 complement(1027300..1027479) 1 NC_010698.2 hypothetical protein 1027479 6297346 HPSH_05205 Helicobacter pylori Shi470 hypothetical protein YP_001910488.1 1027300 R 512562 CDS YP_001910489.1 188527802 6297344 complement(1027745..1028107) 1 NC_010698.2 COG1570 Exonuclease VII, large subunit; exodeoxyribonuclease VII large subunit 1028107 xseA 6297344 xseA Helicobacter pylori Shi470 exodeoxyribonuclease VII large subunit YP_001910489.1 1027745 R 512562 CDS YP_001910490.1 188527803 6297343 complement(1028113..1028193) 1 NC_010698.2 hypothetical protein 1028193 6297343 HPSH_05215 Helicobacter pylori Shi470 hypothetical protein YP_001910490.1 1028113 R 512562 CDS YP_001910491.1 188527804 6297342 complement(1028402..1029136) 1 NC_010698.2 hypothetical protein 1029136 6297342 HPSH_05220 Helicobacter pylori Shi470 hypothetical protein YP_001910491.1 1028402 R 512562 CDS YP_001910492.1 188527805 6297341 complement(1029146..1029367) 1 NC_010698.2 hypothetical protein 1029367 6297341 HPSH_05225 Helicobacter pylori Shi470 hypothetical protein YP_001910492.1 1029146 R 512562 CDS YP_001910493.1 188527806 6297340 complement(1029367..1029702) 1 NC_010698.2 hypothetical protein 1029702 6297340 HPSH_05230 Helicobacter pylori Shi470 hypothetical protein YP_001910493.1 1029367 R 512562 CDS YP_001910494.1 188527807 6297517 complement(1029689..1030114) 1 NC_010698.2 COG0343 Queuine/archaeosine tRNA-ribosyltransferase; hypothetical protein 1030114 6297517 HPSH_05235 Helicobacter pylori Shi470 hypothetical protein YP_001910494.1 1029689 R 512562 CDS YP_001910495.1 188527808 6297336 complement(1030253..1030675) 1 NC_010698.2 hypothetical protein 1030675 6297336 HPSH_05240 Helicobacter pylori Shi470 hypothetical protein YP_001910495.1 1030253 R 512562 CDS YP_001910496.1 188527809 6297335 complement(1030685..1030963) 1 NC_010698.2 hypothetical protein 1030963 6297335 HPSH_05245 Helicobacter pylori Shi470 hypothetical protein YP_001910496.1 1030685 R 512562 CDS YP_001910497.1 188527810 6297334 complement(1030976..1031629) 1 NC_010698.2 COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain; phage/colicin/tellurite resistance cluster terY protein 1031629 6297334 HPSH_05250 Helicobacter pylori Shi470 phage/colicin/tellurite resistance cluster terY protein YP_001910497.1 1030976 R 512562 CDS YP_001910498.1 188527811 6297330 complement(1036094..1036360) 1 NC_010698.2 hypothetical protein 1036360 6297330 HPSH_05255 Helicobacter pylori Shi470 hypothetical protein YP_001910498.1 1036094 R 512562 CDS YP_001910499.1 188527812 6297329 1036552..1038303 1 NC_010698.2 COG1479 Uncharacterized conserved protein; hypothetical protein 1038303 6297329 HPSH_05260 Helicobacter pylori Shi470 hypothetical protein YP_001910499.1 1036552 D 512562 CDS YP_001910500.1 188527813 6297328 1041604..1042443 1 NC_010698.2 hypothetical protein 1042443 6297328 HPSH_05290 Helicobacter pylori Shi470 hypothetical protein YP_001910500.1 1041604 D 512562 CDS YP_001910501.1 188527814 6297327 1042450..1042539 1 NC_010698.2 hypothetical protein 1042539 6297327 HPSH_05295 Helicobacter pylori Shi470 hypothetical protein YP_001910501.1 1042450 D 512562 CDS YP_001910502.1 188527815 6297326 complement(1042645..1044492) 1 NC_010698.2 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 1044492 6297326 HPSH_05300 Helicobacter pylori Shi470 arginine decarboxylase YP_001910502.1 1042645 R 512562 CDS YP_001910503.1 188527816 6297322 complement(1044507..1045676) 1 NC_010698.2 COG0438 Glycosyltransferase; type 1 capsular polysaccharide biosynthesis protein J 1045676 6297322 HPSH_05305 Helicobacter pylori Shi470 type 1 capsular polysaccharide biosynthesis protein J YP_001910503.1 1044507 R 512562 CDS YP_001910504.1 188527817 6297321 complement(1045680..1046108) 1 NC_010698.2 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein 1046108 6297321 HPSH_05310 Helicobacter pylori Shi470 hypothetical protein YP_001910504.1 1045680 R 512562 CDS YP_001910505.1 188527818 6297319 complement(1046124..1046909) 1 NC_010698.2 COG0500 SAM-dependent methyltransferases; hypothetical protein 1046909 6297319 HPSH_05315 Helicobacter pylori Shi470 hypothetical protein YP_001910505.1 1046124 R 512562 CDS YP_001910506.1 188527819 6297318 complement(1046913..1047920) 1 NC_010698.2 hypothetical protein 1047920 6297318 HPSH_05320 Helicobacter pylori Shi470 hypothetical protein YP_001910506.1 1046913 R 512562 CDS YP_001910507.1 188527820 6297317 complement(1047921..1049909) 1 NC_010698.2 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1049909 6297317 HPSH_05325 Helicobacter pylori Shi470 methionyl-tRNA synthetase YP_001910507.1 1047921 R 512562 CDS YP_001910508.1 188527821 6297315 1050079..1051248 1 NC_010698.2 COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane fatty acid synthase 1051248 6297315 HPSH_05330 Helicobacter pylori Shi470 cyclopropane fatty acid synthase YP_001910508.1 1050079 D 512562 CDS YP_001910509.1 188527822 6297095 complement(1051251..1053122) 1 NC_010698.2 COG0668 Small-conductance mechanosensitive channel; hypothetical protein 1053122 6297095 HPSH_05335 Helicobacter pylori Shi470 hypothetical protein YP_001910509.1 1051251 R 512562 CDS YP_001910510.1 188527823 6297306 complement(1054042..1054143) 1 NC_010698.2 hypothetical protein 1054143 6297306 HPSH_05345 Helicobacter pylori Shi470 hypothetical protein YP_001910510.1 1054042 R 512562 CDS YP_001910511.1 188527824 6297304 complement(1054236..1055018) 1 NC_010698.2 hypothetical protein 1055018 6297304 HPSH_05350 Helicobacter pylori Shi470 hypothetical protein YP_001910511.1 1054236 R 512562 CDS YP_001910512.1 188527825 6297303 complement(1055015..1055080) 1 NC_010698.2 hypothetical protein 1055080 6297303 HPSH_05355 Helicobacter pylori Shi470 hypothetical protein YP_001910512.1 1055015 R 512562 CDS YP_001910513.1 188527826 6297302 complement(1055071..1056597) 1 NC_010698.2 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1056597 guaA 6297302 guaA Helicobacter pylori Shi470 GMP synthase YP_001910513.1 1055071 R 512562 CDS YP_001910514.1 188527827 6297301 complement(1056608..1057096) 1 NC_010698.2 hypothetical protein 1057096 6297301 HPSH_05365 Helicobacter pylori Shi470 hypothetical protein YP_001910514.1 1056608 R 512562 CDS YP_001910515.1 188527828 6297300 complement(1057257..1059647) 1 NC_010698.2 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; biotin sulfoxide reductase BisC 1059647 6297300 HPSH_05370 Helicobacter pylori Shi470 biotin sulfoxide reductase BisC YP_001910515.1 1057257 R 512562 CDS YP_001910516.1 188527829 6297299 complement(1059747..1060337) 1 NC_010698.2 hypothetical protein 1060337 6297299 HPSH_05375 Helicobacter pylori Shi470 hypothetical protein YP_001910516.1 1059747 R 512562 CDS YP_001910517.1 188527830 6297296 complement(1060363..1061685) 1 NC_010698.2 COG0520 Selenocysteine lyase; nifS-like protein 1061685 6297296 HPSH_05380 Helicobacter pylori Shi470 nifS-like protein YP_001910517.1 1060363 R 512562 CDS YP_001910518.1 188527831 6297295 complement(1061704..1062018) 1 NC_010698.2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; protein kinase C inhibitor 1062018 6297295 HPSH_05385 Helicobacter pylori Shi470 protein kinase C inhibitor YP_001910518.1 1061704 R 512562 CDS YP_001910519.1 188527832 6297436 1062099..1063085 1 NC_010698.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1063085 pheS 6297436 pheS Helicobacter pylori Shi470 phenylalanyl-tRNA synthetase subunit alpha YP_001910519.1 1062099 D 512562 CDS YP_001910520.1 188527833 6297292 1063085..1065379 1 NC_010698.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1065379 pheT 6297292 pheT Helicobacter pylori Shi470 phenylalanyl-tRNA synthetase subunit beta YP_001910520.1 1063085 D 512562 CDS YP_001910521.1 188527834 6297291 1065395..1066684 1 NC_010698.2 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1066684 6297291 HPSH_05400 Helicobacter pylori Shi470 3-phosphoshikimate 1-carboxyvinyltransferase YP_001910521.1 1065395 D 512562 CDS YP_001910522.1 188527835 6297290 1066674..1067498 1 NC_010698.2 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1067498 ispH 6297290 ispH Helicobacter pylori Shi470 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001910522.1 1066674 D 512562 CDS YP_001910523.1 188527836 6297287 1067619..1069277 1 NC_010698.2 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1069277 rpsA 6297287 rpsA Helicobacter pylori Shi470 30S ribosomal protein S1 YP_001910523.1 1067619 D 512562 CDS YP_001910524.1 188527837 6297286 1069306..1069650 1 NC_010698.2 hypothetical protein 1069650 6297286 HPSH_05415 Helicobacter pylori Shi470 hypothetical protein YP_001910524.1 1069306 D 512562 CDS YP_001910525.1 188527838 6297284 1069839..1071413 1 NC_010698.2 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1071413 6297284 HPSH_05420 Helicobacter pylori Shi470 D-3-phosphoglycerate dehydrogenase YP_001910525.1 1069839 D 512562 CDS YP_001910526.1 188527839 6297283 1071423..1073273 1 NC_010698.2 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; hypothetical protein 1073273 6297283 HPSH_05425 Helicobacter pylori Shi470 hypothetical protein YP_001910526.1 1071423 D 512562 CDS YP_001910527.1 188527840 6297282 1073283..1073951 1 NC_010698.2 COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein 1073951 6297282 HPSH_05430 Helicobacter pylori Shi470 hypothetical protein YP_001910527.1 1073283 D 512562 CDS YP_001910528.1 188527841 6297281 1073953..1074711 1 NC_010698.2 COG2908 Uncharacterized protein conserved in bacteria; hypothetical protein 1074711 6297281 HPSH_05435 Helicobacter pylori Shi470 hypothetical protein YP_001910528.1 1073953 D 512562 CDS YP_001910529.1 188527842 6297279 1074715..1075650 1 NC_010698.2 COG0835 Chemotaxis signal transduction protein; CheA-MCP interaction modulator 1075650 6297279 HPSH_05440 Helicobacter pylori Shi470 CheA-MCP interaction modulator YP_001910529.1 1074715 D 512562 CDS YP_001910530.1 188527843 6297278 1075708..1078152 1 NC_010698.2 COG0643 Chemotaxis protein histidine kinase and related kinases; autophosphorylating histidine kinase 1078152 6297278 HPSH_05445 Helicobacter pylori Shi470 autophosphorylating histidine kinase YP_001910530.1 1075708 D 512562 CDS YP_001910531.1 188527844 6297276 1078149..1078646 1 NC_010698.2 COG0835 Chemotaxis signal transduction protein; purine-binding chemotaxis protein CheW 1078646 6297276 HPSH_05450 Helicobacter pylori Shi470 purine-binding chemotaxis protein CheW YP_001910531.1 1078149 D 512562 CDS YP_001910532.1 188527845 6297273 complement(1078910..1079410) 1 NC_010698.2 COG2077 Peroxiredoxin; thiol peroxidase 1079410 6297273 HPSH_05455 Helicobacter pylori Shi470 thiol peroxidase YP_001910532.1 1078910 R 512562 CDS YP_001910533.1 188527846 6297270 1079634..1080275 1 NC_010698.2 COG0605 Superoxide dismutase; iron-dependent superoxide dismutase 1080275 6297270 HPSH_05460 Helicobacter pylori Shi470 iron-dependent superoxide dismutase YP_001910533.1 1079634 D 512562 CDS YP_001910534.1 188527847 6297269 1080327..1081046 1 NC_010698.2 COG0500 SAM-dependent methyltransferases; hypothetical protein 1081046 6297269 HPSH_05465 Helicobacter pylori Shi470 hypothetical protein YP_001910534.1 1080327 D 512562 CDS YP_001910535.1 188527848 6297268 complement(1081074..1082933) 1 NC_010698.2 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1082933 6297268 HPSH_05470 Helicobacter pylori Shi470 primosome assembly protein PriA YP_001910535.1 1081074 R 512562 CDS YP_001910536.1 188527849 6297267 complement(1082918..1083154) 1 NC_010698.2 hypothetical protein 1083154 6297267 HPSH_05475 Helicobacter pylori Shi470 hypothetical protein YP_001910536.1 1082918 R 512562 CDS YP_001910537.1 188527850 6297266 complement(1083167..1083394) 1 NC_010698.2 COG0055 F0F1-type ATP synthase, beta subunit; hypothetical protein 1083394 6297266 HPSH_05480 Helicobacter pylori Shi470 hypothetical protein YP_001910537.1 1083167 R 512562 CDS YP_001910538.1 188527851 6297200 1083597..1084343 1 NC_010698.2 hypothetical protein 1084343 6297200 HPSH_05485 Helicobacter pylori Shi470 hypothetical protein YP_001910538.1 1083597 D 512562 CDS YP_001910539.1 188527852 6297418 complement(1084351..1084878) 1 NC_010698.2 hypothetical protein 1084878 6297418 HPSH_05490 Helicobacter pylori Shi470 hypothetical protein YP_001910539.1 1084351 R 512562 CDS YP_001910540.1 188527853 6296116 1084844..1084981 1 NC_010698.2 hypothetical protein 1084981 6296116 HPSH_05495 Helicobacter pylori Shi470 hypothetical protein YP_001910540.1 1084844 D 512562 CDS YP_001910541.1 188527854 6297262 1086271..1087101 1 NC_010698.2 COG2890 Methylase of polypeptide chain release factors; protoporphyrinogen oxidase HemK 1087101 6297262 HPSH_05510 Helicobacter pylori Shi470 protoporphyrinogen oxidase HemK YP_001910541.1 1086271 D 512562 CDS YP_001910542.1 188527855 6297261 1087168..1088514 1 NC_010698.2 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1088514 6297261 HPSH_05515 Helicobacter pylori Shi470 glutamate dehydrogenase YP_001910542.1 1087168 D 512562 CDS YP_001910543.1 188527856 6297259 complement(1088529..1089890) 1 NC_010698.2 alpha-(1,3)-fucosyltransferase 1089890 6297259 HPSH_05520 Helicobacter pylori Shi470 alpha-(1,3)-fucosyltransferase YP_001910543.1 1088529 R 512562 CDS YP_001910544.1 188527857 6297258 complement(1089900..1092710) 1 NC_010698.2 COG1333 ResB protein required for cytochrome c biosynthesis; cytochrome c-type biogenesis protein 1092710 6297258 HPSH_05525 Helicobacter pylori Shi470 cytochrome c-type biogenesis protein YP_001910544.1 1089900 R 512562 CDS YP_001910545.1 188527858 6297257 complement(1092719..1093390) 1 NC_010698.2 COG2143 Thioredoxin-related protein; hypothetical protein 1093390 6297257 HPSH_05530 Helicobacter pylori Shi470 hypothetical protein YP_001910545.1 1092719 R 512562 CDS YP_001910546.1 188527859 6297256 complement(1093463..1094470) 1 NC_010698.2 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1094470 hemH 6297256 hemH Helicobacter pylori Shi470 ferrochelatase YP_001910546.1 1093463 R 512562 CDS YP_001910547.1 188527860 6297255 1094526..1094957 1 NC_010698.2 hypothetical protein 1094957 6297255 HPSH_05540 Helicobacter pylori Shi470 hypothetical protein YP_001910547.1 1094526 D 512562 CDS YP_001910548.1 188527861 6297253 1094958..1095638 1 NC_010698.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1095638 6297253 HPSH_05545 Helicobacter pylori Shi470 16S ribosomal RNA methyltransferase RsmE YP_001910548.1 1094958 D 512562 CDS YP_001910549.1 188527862 6297252 complement(1095662..1097890) 1 NC_010698.2 putative outer membrane protein 1097890 6297252 HPSH_05550 Helicobacter pylori Shi470 putative outer membrane protein YP_001910549.1 1095662 R 512562 CDS YP_001910550.1 188527863 6297251 complement(1098049..1098615) 1 NC_010698.2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1098615 dcd 6297251 dcd Helicobacter pylori Shi470 deoxycytidine triphosphate deaminase YP_001910550.1 1098049 R 512562 CDS YP_001910551.1 188527864 6297249 1098745..1099215 1 NC_010698.2 COG0511 Biotin carboxyl carrier protein; biotin carboxyl carrier protein FabE 1099215 6297249 HPSH_05560 Helicobacter pylori Shi470 biotin carboxyl carrier protein FabE YP_001910551.1 1098745 D 512562 CDS YP_001910552.1 188527865 6297248 1099221..1100588 1 NC_010698.2 biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1100588 6297248 HPSH_05565 Helicobacter pylori Shi470 biotin carboxylase YP_001910552.1 1099221 D 512562 CDS YP_001910553.1 188527866 6297247 1100681..1101643 1 NC_010698.2 putative type II DNA modification enzyme methyltransferase 1101643 6297247 HPSH_05570 Helicobacter pylori Shi470 putative type II DNA modification enzyme methyltransferase YP_001910553.1 1100681 D 512562 CDS YP_001910554.1 188527867 6297246 1101643..1102191 1 NC_010698.2 hypothetical protein 1102191 6297246 HPSH_05575 Helicobacter pylori Shi470 hypothetical protein YP_001910554.1 1101643 D 512562 CDS YP_001910555.1 188527868 6297356 1102240..1102884 1 NC_010698.2 hypothetical protein 1102884 6297356 HPSH_05580 Helicobacter pylori Shi470 hypothetical protein YP_001910555.1 1102240 D 512562 CDS YP_001910556.1 188527869 6297243 1102881..1104008 1 NC_010698.2 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; spore coat polysaccharide biosynthesis protein C 1104008 6297243 HPSH_05585 Helicobacter pylori Shi470 spore coat polysaccharide biosynthesis protein C YP_001910556.1 1102881 D 512562 CDS YP_001910557.1 188527870 6297239 1104330..1105355 1 NC_010698.2 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1105355 nrdF 6297239 nrdF Helicobacter pylori Shi470 ribonucleotide-diphosphate reductase subunit beta YP_001910557.1 1104330 D 512562 CDS YP_001910558.1 188527871 6297238 1105365..1105994 1 NC_010698.2 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1105994 pcm 6297238 pcm Helicobacter pylori Shi470 protein-L-isoaspartate O-methyltransferase YP_001910558.1 1105365 D 512562 CDS YP_001910559.1 188527872 6297237 1106005..1107042 1 NC_010698.2 COG0795 Predicted permeases; hypothetical protein 1107042 6297237 HPSH_05605 Helicobacter pylori Shi470 hypothetical protein YP_001910559.1 1106005 D 512562 CDS YP_001910560.1 188527873 6297235 1107043..1107771 1 NC_010698.2 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1107771 truA 6297235 truA Helicobacter pylori Shi470 tRNA pseudouridine synthase A YP_001910560.1 1107043 D 512562 CDS YP_001910561.1 188527874 6297234 complement(1107765..1108799) 1 NC_010698.2 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 1108799 6297234 HPSH_05615 Helicobacter pylori Shi470 UDP-glucose 4-epimerase YP_001910561.1 1107765 R 512562 CDS YP_001910562.1 188527875 6297228 1109329..1110864 1 NC_010698.2 putative outer membrane protein 1110864 6297228 HPSH_05630 Helicobacter pylori Shi470 putative outer membrane protein YP_001910562.1 1109329 D 512562 CDS YP_001910563.1 188527876 6297227 1110886..1111638 1 NC_010698.2 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; short chain alcohol dehydrogenase 1111638 6297227 HPSH_05635 Helicobacter pylori Shi470 short chain alcohol dehydrogenase YP_001910563.1 1110886 D 512562 CDS YP_001910564.1 188527877 6297226 complement(1111825..1112697) 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 1112697 6297226 HPSH_05640 Helicobacter pylori Shi470 hypothetical protein YP_001910564.1 1111825 R 512562 CDS YP_001910565.1 188527878 6297224 complement(1112767..1113393) 1 NC_010698.2 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase 1113393 6297224 HPSH_05645 Helicobacter pylori Shi470 2-keto-3-deoxy-6-phosphogluconate aldolase YP_001910565.1 1112767 R 512562 CDS YP_001910566.1 188527879 6297223 complement(1113412..1115238) 1 NC_010698.2 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1115238 6297223 HPSH_05650 Helicobacter pylori Shi470 phosphogluconate dehydratase YP_001910566.1 1113412 R 512562 CDS YP_001910567.1 188527880 6297222 1115304..1116581 1 NC_010698.2 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1116581 6297222 HPSH_05655 Helicobacter pylori Shi470 glucose-6-phosphate 1-dehydrogenase YP_001910567.1 1115304 D 512562 CDS YP_001910568.1 188527881 6297045 1116592..1117275 1 NC_010698.2 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; glucose-6-phosphate 1-dehydrogenase DevB 1117275 6297045 HPSH_05660 Helicobacter pylori Shi470 glucose-6-phosphate 1-dehydrogenase DevB YP_001910568.1 1116592 D 512562 CDS YP_001910569.1 188527882 6297293 1117262..1118272 1 NC_010698.2 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1118272 glk 6297293 glk Helicobacter pylori Shi470 glucokinase YP_001910569.1 1117262 D 512562 CDS YP_001910570.1 188527883 6297419 1118434..1119486 1 NC_010698.2 COG1064 Zn-dependent alcohol dehydrogenases; NADP-dependent alcohol dehydrogenase 1119486 6297419 HPSH_05670 Helicobacter pylori Shi470 NADP-dependent alcohol dehydrogenase YP_001910570.1 1118434 D 512562 CDS YP_001910571.1 188527884 6297221 complement(1119498..1120658) 1 NC_010698.2 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; putative lipopolysaccharide biosynthesis protein 1120658 6297221 HPSH_05675 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001910571.1 1119498 R 512562 CDS YP_001910572.1 188527885 6297220 complement(1120791..1121981) 1 NC_010698.2 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; putative lipopolysaccharide biosynthesis protein 1121981 6297220 HPSH_05680 Helicobacter pylori Shi470 putative lipopolysaccharide biosynthesis protein YP_001910572.1 1120791 R 512562 CDS YP_001910573.1 188527886 6297219 1122161..1123468 1 NC_010698.2 hypothetical protein 1123468 6297219 HPSH_05685 Helicobacter pylori Shi470 hypothetical protein YP_001910573.1 1122161 D 512562 CDS YP_001910574.1 188527887 6297218 complement(1123475..1124146) 1 NC_010698.2 outer membrane protein 1124146 6297218 HPSH_05690 Helicobacter pylori Shi470 outer membrane protein YP_001910574.1 1123475 R 512562 CDS YP_001910575.1 188527888 6297217 1124436..1124996 1 NC_010698.2 COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; pyruvate flavodoxin oxidoreductase subunit gamma 1124996 6297217 HPSH_05695 Helicobacter pylori Shi470 pyruvate flavodoxin oxidoreductase subunit gamma YP_001910575.1 1124436 D 512562 CDS YP_001910576.1 188527889 6297214 1125012..1125404 1 NC_010698.2 COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit; pyruvate flavodoxin oxidoreductase subunit delta 1125404 porD 6297214 porD Helicobacter pylori Shi470 pyruvate flavodoxin oxidoreductase subunit delta YP_001910576.1 1125012 D 512562 CDS YP_001910577.1 188527890 6297213 1125414..1126637 1 NC_010698.2 COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; pyruvate flavodoxin oxidoreductase subunit alpha 1126637 porA 6297213 porA Helicobacter pylori Shi470 pyruvate flavodoxin oxidoreductase subunit alpha YP_001910577.1 1125414 D 512562 CDS YP_001910578.1 188527891 6297212 1126650..1127594 1 NC_010698.2 COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; pyruvate ferredoxin oxidoreductase subunit beta 1127594 6297212 HPSH_05710 Helicobacter pylori Shi470 pyruvate ferredoxin oxidoreductase subunit beta YP_001910578.1 1126650 D 512562 CDS YP_001910579.1 188527892 6297211 1127704..1129026 1 NC_010698.2 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1129026 6297211 HPSH_05715 Helicobacter pylori Shi470 adenylosuccinate lyase YP_001910579.1 1127704 D 512562 CDS YP_001910580.1 188527893 6297210 1129095..1129928 1 NC_010698.2 outer membrane protein Horl 1129928 6297210 HPSH_05720 Helicobacter pylori Shi470 outer membrane protein Horl YP_001910580.1 1129095 D 512562 CDS YP_001910581.1 188527894 6297209 complement(1129925..1131901) 1 NC_010698.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1131901 6297209 HPSH_05725 Helicobacter pylori Shi470 excinuclease ABC subunit B YP_001910581.1 1129925 R 512562 CDS YP_001910582.1 188527895 6297205 complement(1132042..1132425) 1 NC_010698.2 hypothetical protein 1132425 6297205 HPSH_05730 Helicobacter pylori Shi470 hypothetical protein YP_001910582.1 1132042 R 512562 CDS YP_001910583.1 188527896 6297204 complement(1132422..1133630) 1 NC_010698.2 hypothetical protein 1133630 6297204 HPSH_05735 Helicobacter pylori Shi470 hypothetical protein YP_001910583.1 1132422 R 512562 CDS YP_001910584.1 188527897 6297203 complement(1133983..1134060) 1 NC_010698.2 hypothetical protein 1134060 6297203 HPSH_05740 Helicobacter pylori Shi470 hypothetical protein YP_001910584.1 1133983 R 512562 CDS YP_001910585.1 188527898 6297202 complement(1134057..1134827) 1 NC_010698.2 COG0790 FOG: TPR repeat, SEL1 subfamily; cysteine-rich protein X 1134827 6297202 HPSH_05745 Helicobacter pylori Shi470 cysteine-rich protein X YP_001910585.1 1134057 R 512562 CDS YP_001910586.1 188527899 6297265 complement(1134830..1134919) 1 NC_010698.2 hypothetical protein 1134919 6297265 HPSH_05750 Helicobacter pylori Shi470 hypothetical protein YP_001910586.1 1134830 R 512562 CDS YP_001910587.1 188527900 6297198 complement(1135096..1136799) 1 NC_010698.2 COG0405 Gamma-glutamyltransferase; gamma-glutamyltranspeptidase 1136799 6297198 HPSH_05755 Helicobacter pylori Shi470 gamma-glutamyltranspeptidase YP_001910587.1 1135096 R 512562 CDS YP_001910588.1 188527901 6297197 complement(1137004..1138824) 1 NC_010698.2 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1138824 flgK 6297197 flgK Helicobacter pylori Shi470 flagellar hook-associated protein FlgK YP_001910588.1 1137004 R 512562 CDS YP_001910589.1 188527902 6297196 complement(1138826..1139260) 1 NC_010698.2 hypothetical protein 1139260 6297196 HPSH_05765 Helicobacter pylori Shi470 hypothetical protein YP_001910589.1 1138826 R 512562 CDS YP_001910590.1 188527903 6297195 complement(1139390..1140352) 1 NC_010698.2 COG0270 Site-specific DNA methylase; type II DNA modification methyltransferase 1140352 6297195 HPSH_05770 Helicobacter pylori Shi470 type II DNA modification methyltransferase YP_001910590.1 1139390 R 512562 CDS YP_001910591.1 188527904 6297193 1140373..1140462 1 NC_010698.2 hypothetical protein 1140462 6297193 HPSH_05775 Helicobacter pylori Shi470 hypothetical protein YP_001910591.1 1140373 D 512562 CDS YP_001910592.1 188527905 6297192 complement(1140483..1140686) 1 NC_010698.2 flgM protein 1140686 6297192 HPSH_05780 Helicobacter pylori Shi470 flgM protein YP_001910592.1 1140483 R 512562 CDS YP_001910593.1 188527906 6297191 complement(1140750..1140956) 1 NC_010698.2 hypothetical protein 1140956 6297191 HPSH_05785 Helicobacter pylori Shi470 hypothetical protein YP_001910593.1 1140750 R 512562 CDS YP_001910594.1 188527907 6297190 complement(1140988..1141536) 1 NC_010698.2 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; peptidyl-prolyl cis-trans isomerase 1141536 6297190 HPSH_05790 Helicobacter pylori Shi470 peptidyl-prolyl cis-trans isomerase YP_001910594.1 1140988 R 512562 CDS YP_001910595.1 188527908 6297189 complement(1141523..1142518) 1 NC_010698.2 hypothetical protein 1142518 6297189 HPSH_05795 Helicobacter pylori Shi470 hypothetical protein YP_001910595.1 1141523 R 512562 CDS YP_001910596.1 188527909 6297188 complement(1142526..1143077) 1 NC_010698.2 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated lipoprotein 1143077 6297188 HPSH_05800 Helicobacter pylori Shi470 peptidoglycan-associated lipoprotein YP_001910596.1 1142526 R 512562 CDS YP_001910597.1 188527910 6297187 complement(1143144..1144397) 1 NC_010698.2 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1144397 tolB 6297187 tolB Helicobacter pylori Shi470 translocation protein TolB YP_001910597.1 1143144 R 512562 CDS YP_001910598.1 188527911 6297185 complement(1144394..1145206) 1 NC_010698.2 hypothetical protein 1145206 6297185 HPSH_05810 Helicobacter pylori Shi470 hypothetical protein YP_001910598.1 1144394 R 512562 CDS YP_001910599.1 188527912 6297182 complement(1145225..1145626) 1 NC_010698.2 COG0848 Biopolymer transport protein; biopolymer transport protein 1145626 6297182 HPSH_05815 Helicobacter pylori Shi470 biopolymer transport protein YP_001910599.1 1145225 R 512562 CDS YP_001910600.1 188527913 6297181 complement(1145679..1146248) 1 NC_010698.2 COG0811 Biopolymer transport proteins; biopolymer transport protein 1146248 6297181 HPSH_05820 Helicobacter pylori Shi470 biopolymer transport protein YP_001910600.1 1145679 R 512562 CDS YP_001910601.1 188527914 6297180 complement(1146259..1146630) 1 NC_010698.2 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1146630 atpC 6297180 atpC Helicobacter pylori Shi470 F0F1 ATP synthase subunit epsilon YP_001910601.1 1146259 R 512562 CDS YP_001910602.1 188527915 6297178 complement(1146641..1148050) 1 NC_010698.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1148050 6297178 HPSH_05830 Helicobacter pylori Shi470 F0F1 ATP synthase subunit beta YP_001910602.1 1146641 R 512562 CDS YP_001910603.1 188527916 6297177 complement(1148070..1148975) 1 NC_010698.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1148975 6297177 HPSH_05835 Helicobacter pylori Shi470 F0F1 ATP synthase subunit gamma YP_001910603.1 1148070 R 512562 CDS YP_001910604.1 188527917 6297147 complement(1148990..1150501) 1 NC_010698.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1150501 6297147 HPSH_05840 Helicobacter pylori Shi470 F0F1 ATP synthase subunit alpha YP_001910604.1 1148990 R 512562 CDS YP_001910605.1 188527918 6297380 complement(1150524..1151066) 1 NC_010698.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1151066 6297380 HPSH_05845 Helicobacter pylori Shi470 F0F1 ATP synthase subunit delta YP_001910605.1 1150524 R 512562 CDS YP_001910606.1 188527919 6296425 complement(1151067..1151582) 1 NC_010698.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1151582 6296425 HPSH_05850 Helicobacter pylori Shi470 F0F1 ATP synthase subunit B YP_001910606.1 1151067 R 512562 CDS YP_001910607.1 188527920 6297174 complement(1151586..1152020) 1 NC_010698.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 1152020 6297174 HPSH_05855 Helicobacter pylori Shi470 F0F1 ATP synthase subunit B' YP_001910607.1 1151586 R 512562 CDS YP_001910608.1 188527921 6297173 complement(1152131..1153003) 1 NC_010698.2 COG1475 Predicted transcriptional regulators; plasmid replication-partition-like protein 1153003 6297173 HPSH_05860 Helicobacter pylori Shi470 plasmid replication-partition-like protein YP_001910608.1 1152131 R 512562 CDS YP_001910609.1 188527922 6297172 complement(1153006..1153803) 1 NC_010698.2 COG1192 ATPases involved in chromosome partitioning; SpoOJ regulator (soj) 1153803 6297172 HPSH_05865 Helicobacter pylori Shi470 SpoOJ regulator (soj) YP_001910609.1 1153006 R 512562 CDS YP_001910610.1 188527923 6297170 complement(1153806..1154444) 1 NC_010698.2 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1154444 6297170 HPSH_05870 Helicobacter pylori Shi470 biotin--protein ligase YP_001910610.1 1153806 R 512562 CDS YP_001910611.1 188527924 6297169 complement(1154441..1155337) 1 NC_010698.2 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1155337 fmt 6297169 fmt Helicobacter pylori Shi470 methionyl-tRNA formyltransferase YP_001910611.1 1154441 R 512562 CDS YP_001910612.1 188527925 6297168 complement(1157863..1159161) 1 NC_010698.2 COG4487 Uncharacterized protein conserved in bacteria; hypothetical protein 1159161 6297168 HPSH_05890 Helicobacter pylori Shi470 hypothetical protein YP_001910612.1 1157863 R 512562 CDS YP_001910613.1 188527926 6297166 1159424..1159531 1 NC_010698.2 hypothetical protein 1159531 6297166 HPSH_05895 Helicobacter pylori Shi470 hypothetical protein YP_001910613.1 1159424 D 512562 CDS YP_001910614.1 188527927 6297165 complement(1159918..1160013) 1 NC_010698.2 hypothetical protein 1160013 6297165 HPSH_05900 Helicobacter pylori Shi470 hypothetical protein YP_001910614.1 1159918 R 512562 CDS YP_001910615.1 188527928 6297159 1162228..1162320 1 NC_010698.2 hypothetical protein 1162320 6297159 HPSH_05905 Helicobacter pylori Shi470 hypothetical protein YP_001910615.1 1162228 D 512562 CDS YP_001910616.1 188527929 6297154 complement(1162317..1163117) 1 NC_010698.2 COG1432 Uncharacterized conserved protein; hypothetical protein 1163117 6297154 HPSH_05910 Helicobacter pylori Shi470 hypothetical protein YP_001910616.1 1162317 R 512562 CDS YP_001910617.1 188527930 6297153 1163177..1163266 1 NC_010698.2 hypothetical protein 1163266 6297153 HPSH_05915 Helicobacter pylori Shi470 hypothetical protein YP_001910617.1 1163177 D 512562 CDS YP_001910618.1 188527931 6297150 complement(1163421..1163777) 1 NC_010698.2 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1163777 rplS 6297150 rplS Helicobacter pylori Shi470 50S ribosomal protein L19 YP_001910618.1 1163421 R 512562 CDS YP_001910619.1 188527932 6297148 complement(1163799..1164488) 1 NC_010698.2 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1164488 trmD 6297148 trmD Helicobacter pylori Shi470 tRNA (guanine-N(1)-)-methyltransferase YP_001910619.1 1163799 R 512562 CDS YP_001910620.1 188527933 6297175 complement(1164489..1165043) 1 NC_010698.2 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1165043 rimM 6297175 rimM Helicobacter pylori Shi470 16S rRNA-processing protein RimM YP_001910620.1 1164489 R 512562 CDS YP_001910621.1 188527934 6297145 complement(1165044..1165391) 1 NC_010698.2 COG1837 Predicted RNA-binding protein (contains KH domain); hypothetical protein 1165391 6297145 HPSH_05935 Helicobacter pylori Shi470 hypothetical protein YP_001910621.1 1165044 R 512562 CDS YP_001910622.1 188527935 6297144 complement(1165408..1165638) 1 NC_010698.2 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1165638 rpsP 6297144 rpsP Helicobacter pylori Shi470 30S ribosomal protein S16 YP_001910622.1 1165408 R 512562 CDS YP_001910623.1 188527936 6297143 complement(1165712..1167058) 1 NC_010698.2 COG0541 Signal recognition particle GTPase; signal recognition particle protein 1167058 6297143 HPSH_05945 Helicobacter pylori Shi470 signal recognition particle protein YP_001910623.1 1165712 R 512562 CDS YP_001910624.1 188527937 6297142 complement(1167073..1169691) 1 NC_010698.2 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1169691 valS 6297142 valS Helicobacter pylori Shi470 valyl-tRNA synthetase YP_001910624.1 1167073 R 512562 CDS YP_001910625.1 188527938 6297141 1169829..1170236 1 NC_010698.2 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1170236 6297141 HPSH_05955 Helicobacter pylori Shi470 flagellar assembly protein FliW YP_001910625.1 1169829 D 512562 CDS YP_001910626.1 188527939 6297138 1170248..1171309 1 NC_010698.2 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1171309 murG 6297138 murG Helicobacter pylori Shi470 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001910626.1 1170248 D 512562 CDS YP_001910627.1 188527940 6297136 1171417..1173507 1 NC_010698.2 outer membrane protein HopI 1173507 6297136 HPSH_05965 Helicobacter pylori Shi470 outer membrane protein HopI YP_001910627.1 1171417 D 512562 CDS YP_001910628.1 188527941 6297134 1173530..1177219 1 NC_010698.2 outer membrane protein HopL 1177219 6297134 HPSH_05970 Helicobacter pylori Shi470 outer membrane protein HopL YP_001910628.1 1173530 D 512562 CDS YP_001910629.1 188527942 6297133 1177233..1177988 1 NC_010698.2 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1177988 6297133 HPSH_05975 Helicobacter pylori Shi470 pyrroline-5-carboxylate reductase YP_001910629.1 1177233 D 512562 CDS YP_001910630.1 188527943 6297132 1178032..1178565 1 NC_010698.2 COG2184 Protein involved in cell division; cell filamentation protein 1178565 6297132 HPSH_05980 Helicobacter pylori Shi470 cell filamentation protein YP_001910630.1 1178032 D 512562 CDS YP_001910631.1 188527944 6297131 complement(1178623..1179045) 1 NC_010698.2 COG0319 Predicted metal-dependent hydrolase; putative metalloprotease 1179045 6297131 HPSH_05985 Helicobacter pylori Shi470 putative metalloprotease YP_001910631.1 1178623 R 512562 CDS YP_001910632.1 188527945 6297130 complement(1179098..1179592) 1 NC_010698.2 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 1179592 6297130 HPSH_05990 Helicobacter pylori Shi470 flavodoxin FldA YP_001910632.1 1179098 R 512562 CDS YP_001910633.1 188527946 6297129 complement(1179681..1180262) 1 NC_010698.2 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 1180262 6297129 HPSH_05995 Helicobacter pylori Shi470 hypothetical protein YP_001910633.1 1179681 R 512562 CDS YP_001910634.1 188527947 6297128 1180384..1180575 1 NC_010698.2 COG3197 Uncharacterized protein, possibly involved in nitrogen fixation; cation transport subunit for cbb3-type oxidase 1180575 6297128 HPSH_06000 Helicobacter pylori Shi470 cation transport subunit for cbb3-type oxidase YP_001910634.1 1180384 D 512562 CDS YP_001910635.1 188527948 6297127 1180601..1181572 1 NC_010698.2 COG0492 Thioredoxin reductase; thioredoxin reductase 1181572 6297127 HPSH_06005 Helicobacter pylori Shi470 thioredoxin reductase YP_001910635.1 1180601 D 512562 CDS YP_001910636.1 188527949 6297126 1182809..1184446 1 NC_010698.2 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1184446 pgi 6297126 pgi Helicobacter pylori Shi470 glucose-6-phosphate isomerase YP_001910636.1 1182809 D 512562 CDS YP_001910637.1 188527950 6297125 complement(1184434..1184520) 1 NC_010698.2 hypothetical protein 1184520 6297125 HPSH_06025 Helicobacter pylori Shi470 hypothetical protein YP_001910637.1 1184434 R 512562 CDS YP_001910638.1 188527951 6297120 1184755..1186170 1 NC_010698.2 outer membrane protein HofH 1186170 6297120 HPSH_06030 Helicobacter pylori Shi470 outer membrane protein HofH YP_001910638.1 1184755 D 512562 CDS YP_001910639.1 188527952 6296996 complement(1186222..1186341) 1 NC_010698.2 hypothetical protein 1186341 6296996 HPSH_06035 Helicobacter pylori Shi470 hypothetical protein YP_001910639.1 1186222 R 512562 CDS YP_001910640.1 188527953 6297244 complement(1186421..1188496) 1 NC_010698.2 COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein 1188496 6297244 HPSH_06040 Helicobacter pylori Shi470 carbon starvation protein YP_001910640.1 1186421 R 512562 CDS YP_001910641.1 188527954 6296547 1188707..1189360 1 NC_010698.2 COG0765 ABC-type amino acid transport system, permease component; glutamine ABC transporter permease 1189360 6296547 HPSH_06045 Helicobacter pylori Shi470 glutamine ABC transporter permease YP_001910641.1 1188707 D 512562 CDS YP_001910642.1 188527955 6297115 1189363..1190034 1 NC_010698.2 COG0765 ABC-type amino acid transport system, permease component; glutamine ABC transporter permease GlnP 1190034 6297115 HPSH_06050 Helicobacter pylori Shi470 glutamine ABC transporter permease GlnP YP_001910642.1 1189363 D 512562 CDS YP_001910643.1 188527956 6297114 1190036..1190782 1 NC_010698.2 COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein GlnQ 1190782 6297114 HPSH_06055 Helicobacter pylori Shi470 glutamine ABC transporter ATP-binding protein GlnQ YP_001910643.1 1190036 D 512562 CDS YP_001910644.1 188527957 6297113 1190831..1191664 1 NC_010698.2 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; glutamine ABC transporter periplasmic glutamine-binding protein 1191664 6297113 HPSH_06060 Helicobacter pylori Shi470 glutamine ABC transporter periplasmic glutamine-binding protein YP_001910644.1 1190831 D 512562 CDS YP_001910645.1 188527958 6297110 1191657..1191725 1 NC_010698.2 hypothetical protein 1191725 6297110 HPSH_06065 Helicobacter pylori Shi470 hypothetical protein YP_001910645.1 1191657 D 512562 CDS YP_001910646.1 188527959 6297109 1191785..1192336 1 NC_010698.2 hypothetical protein 1192336 6297109 HPSH_06070 Helicobacter pylori Shi470 hypothetical protein YP_001910646.1 1191785 D 512562 CDS YP_001910647.1 188527960 6297107 complement(1192552..1193775) 1 NC_010698.2 COG0738 Fucose permease; glucose/galactose transporter 1193775 6297107 HPSH_06075 Helicobacter pylori Shi470 glucose/galactose transporter YP_001910647.1 1192552 R 512562 CDS YP_001910648.1 188527961 6297106 complement(1193905..1195212) 1 NC_010698.2 COG2252 Permeases; hypothetical protein 1195212 6297106 HPSH_06080 Helicobacter pylori Shi470 hypothetical protein YP_001910648.1 1193905 R 512562 CDS YP_001910649.1 188527962 6297105 complement(1195325..1195408) 1 NC_010698.2 hypothetical protein 1195408 6297105 HPSH_06085 Helicobacter pylori Shi470 hypothetical protein YP_001910649.1 1195325 R 512562 CDS YP_001910650.1 188527963 6297104 1195547..1195684 1 NC_010698.2 hypothetical protein 1195684 6297104 HPSH_06090 Helicobacter pylori Shi470 hypothetical protein YP_001910650.1 1195547 D 512562 CDS YP_001910651.1 188527964 6297102 complement(1195662..1197587) 1 NC_010698.2 outer membrane protein 1197587 6297102 HPSH_06095 Helicobacter pylori Shi470 outer membrane protein YP_001910651.1 1195662 R 512562 CDS YP_001910652.1 188527965 6297101 1197737..1197847 1 NC_010698.2 hypothetical protein 1197847 6297101 HPSH_06100 Helicobacter pylori Shi470 hypothetical protein YP_001910652.1 1197737 D 512562 CDS YP_001910653.1 188527966 6297099 complement(1197859..1198563) 1 NC_010698.2 COG0813 Purine-nucleoside phosphorylase; purine-nucleoside phosphorylase 1198563 6297099 HPSH_06105 Helicobacter pylori Shi470 purine-nucleoside phosphorylase YP_001910653.1 1197859 R 512562 CDS YP_001910654.1 188527967 6297097 complement(1198560..1199801) 1 NC_010698.2 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1199801 6297097 HPSH_06110 Helicobacter pylori Shi470 phosphopentomutase YP_001910654.1 1198560 R 512562 CDS YP_001910655.1 188527968 6297096 complement(1199813..1201069) 1 NC_010698.2 COG1972 Nucleoside permease; pyrimidine nucleoside transport protein NupC 1201069 6297096 HPSH_06115 Helicobacter pylori Shi470 pyrimidine nucleoside transport protein NupC YP_001910655.1 1199813 R 512562 CDS YP_001910656.1 188527969 6297093 1201396..1202727 1 NC_010698.2 COG0477 Permeases of the major facilitator superfamily; multidrug-efflux transporter 1202727 6297093 HPSH_06120 Helicobacter pylori Shi470 multidrug-efflux transporter YP_001910656.1 1201396 D 512562 CDS YP_001910657.1 188527970 6297092 1202745..1203506 1 NC_010698.2 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; hypothetical protein 1203506 6297092 HPSH_06125 Helicobacter pylori Shi470 hypothetical protein YP_001910657.1 1202745 D 512562 CDS YP_001910658.1 188527971 6297091 complement(1203515..1204666) 1 NC_010698.2 COG0475 Kef-type K+ transport systems, membrane components; NA+/H+ antiporter NapA 1204666 6297091 HPSH_06130 Helicobacter pylori Shi470 NA+/H+ antiporter NapA YP_001910658.1 1203515 R 512562 CDS YP_001910659.1 188527972 6297084 complement(1204692..1206071) 1 NC_010698.2 COG0534 Na+-driven multidrug efflux pump; hypothetical protein 1206071 6297084 HPSH_06135 Helicobacter pylori Shi470 hypothetical protein YP_001910659.1 1204692 R 512562 CDS YP_001910660.1 188527973 6297080 complement(1206231..1207403) 1 NC_010698.2 COG2814 Arabinose efflux permease; sugar efflux transporter 1207403 6297080 HPSH_06140 Helicobacter pylori Shi470 sugar efflux transporter YP_001910660.1 1206231 R 512562 CDS YP_001910661.1 188527974 6297078 1207682..1208425 1 NC_010698.2 COG3338 Carbonic anhydrase; carbonic anhydrase 1208425 6297078 HPSH_06145 Helicobacter pylori Shi470 carbonic anhydrase YP_001910661.1 1207682 D 512562 CDS YP_001910662.1 188527975 6297076 1208712..1210526 1 NC_010698.2 hypothetical protein 1210526 6297076 HPSH_06150 Helicobacter pylori Shi470 hypothetical protein YP_001910662.1 1208712 D 512562 CDS YP_001910663.1 188527976 6297075 complement(1210706..1211746) 1 NC_010698.2 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 1211746 6297075 HPSH_06155 Helicobacter pylori Shi470 aspartate-semialdehyde dehydrogenase YP_001910663.1 1210706 R 512562 CDS YP_001910664.1 188527977 6297074 complement(1211733..1213061) 1 NC_010698.2 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1213061 hisS 6297074 hisS Helicobacter pylori Shi470 histidyl-tRNA synthetase YP_001910664.1 1211733 R 512562 CDS YP_001910665.1 188527978 6297073 1213123..1214172 1 NC_010698.2 COG0859 ADP-heptose:LPS heptosyltransferase; ADP-heptose-lps heptosyltransferase II 1214172 6297073 HPSH_06165 Helicobacter pylori Shi470 ADP-heptose-lps heptosyltransferase II YP_001910665.1 1213123 D 512562 CDS YP_001910666.1 188527979 6297070 complement(1214365..1214691) 1 NC_010698.2 hypothetical protein 1214691 6297070 HPSH_06170 Helicobacter pylori Shi470 hypothetical protein YP_001910666.1 1214365 R 512562 CDS YP_001910667.1 188527980 6297069 1214875..1214985 1 NC_010698.2 hypothetical protein 1214985 6297069 HPSH_06175 Helicobacter pylori Shi470 hypothetical protein YP_001910667.1 1214875 D 512562 CDS YP_001910668.1 188527981 6297067 complement(1215233..1217311) 1 NC_010698.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1217311 6297067 HPSH_06180 Helicobacter pylori Shi470 elongation factor G YP_001910668.1 1215233 R 512562 CDS YP_001910669.1 188527982 6297066 complement(1217323..1217790) 1 NC_010698.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1217790 6297066 HPSH_06185 Helicobacter pylori Shi470 30S ribosomal protein S7 YP_001910669.1 1217323 R 512562 CDS YP_001910670.1 188527983 6297065 complement(1217806..1218213) 1 NC_010698.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1218213 rpsL 6297065 rpsL Helicobacter pylori Shi470 30S ribosomal protein S12 YP_001910670.1 1217806 R 512562 CDS YP_001910671.1 188527984 6297064 complement(1218301..1226973) 1 NC_010698.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' 1226973 6297064 HPSH_06195 Helicobacter pylori Shi470 DNA-directed RNA polymerase subunit beta/beta' YP_001910671.1 1218301 R 512562 CDS YP_001910672.1 188527985 6296841 1226967..1227158 1 NC_010698.2 hypothetical protein 1227158 6296841 HPSH_06200 Helicobacter pylori Shi470 hypothetical protein YP_001910672.1 1226967 D 512562 CDS YP_001910673.1 188527986 6297094 complement(1227197..1227574) 1 NC_010698.2 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1227574 rplL 6297094 rplL Helicobacter pylori Shi470 50S ribosomal protein L7/L12 YP_001910673.1 1227197 R 512562 CDS YP_001910674.1 188527987 6296232 complement(1227620..1228114) 1 NC_010698.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1228114 rplJ 6296232 rplJ Helicobacter pylori Shi470 50S ribosomal protein L10 YP_001910674.1 1227620 R 512562 CDS YP_001910675.1 188527988 6297061 complement(1228223..1228927) 1 NC_010698.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1228927 rplA 6297061 rplA Helicobacter pylori Shi470 50S ribosomal protein L1 YP_001910675.1 1228223 R 512562 CDS YP_001910676.1 188527989 6297060 complement(1228972..1229397) 1 NC_010698.2 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1229397 rplK 6297060 rplK Helicobacter pylori Shi470 50S ribosomal protein L11 YP_001910676.1 1228972 R 512562 CDS YP_001910677.1 188527990 6297059 complement(1229415..1229942) 1 NC_010698.2 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1229942 nusG 6297059 nusG Helicobacter pylori Shi470 transcription antitermination protein NusG YP_001910677.1 1229415 R 512562 CDS YP_001910678.1 188527991 6297058 complement(1229972..1230151) 1 NC_010698.2 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1230151 secE 6297058 secE Helicobacter pylori Shi470 preprotein translocase subunit SecE YP_001910678.1 1229972 R 512562 CDS YP_001910679.1 188527992 6297055 complement(1230405..1230563) 1 NC_010698.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1230563 rpmG 6297055 rpmG Helicobacter pylori Shi470 50S ribosomal protein L33 YP_001910679.1 1230405 R 512562 CDS YP_001910680.1 188527993 6297054 complement(1230597..1231796) 1 NC_010698.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1231796 6297054 HPSH_06240 Helicobacter pylori Shi470 elongation factor Tu YP_001910680.1 1230597 R 512562 CDS YP_001910681.1 188527994 6297046 1232519..1234255 1 NC_010698.2 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter ATP-binding protein 1234255 6297046 HPSH_06245 Helicobacter pylori Shi470 ABC transporter ATP-binding protein YP_001910681.1 1232519 D 512562 CDS YP_001910682.1 188527995 6297043 complement(1234264..1234932) 1 NC_010698.2 COG0546 Predicted phosphatases; hypothetical protein 1234932 6297043 HPSH_06250 Helicobacter pylori Shi470 hypothetical protein YP_001910682.1 1234264 R 512562 CDS YP_001910683.1 188527996 6297042 complement(1235036..1236025) 1 NC_010698.2 COG3392 Adenine-specific DNA methylase; ulcer associated adenine specific DNA methyltransferase 1236025 6297042 HPSH_06255 Helicobacter pylori Shi470 ulcer associated adenine specific DNA methyltransferase YP_001910683.1 1235036 R 512562 CDS YP_001910684.1 188527997 6297040 complement(1236380..1236523) 1 NC_010698.2 hypothetical protein 1236523 6297040 HPSH_06260 Helicobacter pylori Shi470 hypothetical protein YP_001910684.1 1236380 R 512562 CDS YP_001910685.1 188527998 6297039 complement(1236745..1237260) 1 NC_010698.2 COG1045 Serine acetyltransferase; serine acetyltransferase 1237260 6297039 HPSH_06265 Helicobacter pylori Shi470 serine acetyltransferase YP_001910685.1 1236745 R 512562 CDS YP_001910686.1 188527999 6297035 complement(1237301..1237420) 1 NC_010698.2 hypothetical protein 1237420 6297035 HPSH_06270 Helicobacter pylori Shi470 hypothetical protein YP_001910686.1 1237301 R 512562 CDS YP_001910687.1 188528000 6297029 complement(1237914..1238231) 1 NC_010698.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1238231 6297029 HPSH_06275 Helicobacter pylori Shi470 F0F1 ATP synthase subunit C YP_001910687.1 1237914 R 512562 CDS YP_001910688.1 188528001 6297026 complement(1238368..1240434) 1 NC_010698.2 COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 1240434 6297026 HPSH_06280 Helicobacter pylori Shi470 polynucleotide phosphorylase/polyadenylase YP_001910688.1 1238368 R 512562 CDS YP_001910689.1 188528002 6297025 complement(1240437..1241141) 1 NC_010698.2 COG1926 Predicted phosphoribosyltransferases; hypothetical protein 1241141 6297025 HPSH_06285 Helicobacter pylori Shi470 hypothetical protein YP_001910689.1 1240437 R 512562 CDS YP_001910690.1 188528003 6297022 complement(1241156..1243417) 1 NC_010698.2 COG1452 Organic solvent tolerance protein OstA; organic solvent tolerance protein 1243417 6297022 HPSH_06290 Helicobacter pylori Shi470 organic solvent tolerance protein YP_001910690.1 1241156 R 512562 CDS YP_001910691.1 188528004 6297021 complement(1243420..1243899) 1 NC_010698.2 hypothetical protein 1243899 6297021 HPSH_06295 Helicobacter pylori Shi470 hypothetical protein YP_001910691.1 1243420 R 512562 CDS YP_001910692.1 188528005 6297020 complement(1243941..1245215) 1 NC_010698.2 COG0151 Phosphoribosylamine-glycine ligase; glycinamide ribonucleotide synthetase 1245215 6297020 HPSH_06300 Helicobacter pylori Shi470 glycinamide ribonucleotide synthetase YP_001910692.1 1243941 R 512562 CDS YP_001910693.1 188528006 6297019 1245335..1245526 1 NC_010698.2 hypothetical protein 1245526 6297019 HPSH_06305 Helicobacter pylori Shi470 hypothetical protein YP_001910693.1 1245335 D 512562 CDS YP_001910694.1 188528007 6297018 complement(1245528..1246214) 1 NC_010698.2 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 1246214 6297018 HPSH_06310 Helicobacter pylori Shi470 ABC transporter ATP-binding protein YP_001910694.1 1245528 R 512562 CDS YP_001910695.1 188528008 6296943 complement(1246208..1246912) 1 NC_010698.2 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1246912 6296943 HPSH_06315 Helicobacter pylori Shi470 undecaprenyl pyrophosphate synthase YP_001910695.1 1246208 R 512562 CDS YP_001910696.1 188528009 6297199 complement(1246952..1249792) 1 NC_010698.2 COG0277 FAD/FMN-containing dehydrogenases; D-lactate dehydrogenase 1249792 6297199 HPSH_06320 Helicobacter pylori Shi470 D-lactate dehydrogenase YP_001910696.1 1246952 R 512562 CDS YP_001910697.1 188528010 6296196 1249864..1250196 1 NC_010698.2 COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 1250196 6296196 HPSH_06325 Helicobacter pylori Shi470 hypothetical protein YP_001910697.1 1249864 D 512562 CDS YP_001910698.1 188528011 6297015 1250199..1250879 1 NC_010698.2 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1250879 hemD 6297015 hemD Helicobacter pylori Shi470 uroporphyrinogen-III synthase YP_001910698.1 1250199 D 512562 CDS YP_001910699.1 188528012 6297014 1250926..1251318 1 NC_010698.2 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1251318 6297014 HPSH_06335 Helicobacter pylori Shi470 camphor resistance protein CrcB YP_001910699.1 1250926 D 512562 CDS YP_001910700.1 188528013 6297012 complement(1251364..1252401) 1 NC_010698.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1252401 6297012 HPSH_06340 Helicobacter pylori Shi470 coproporphyrinogen III oxidase YP_001910700.1 1251364 R 512562 CDS YP_001910701.1 188528014 6297011 1252497..1252787 1 NC_010698.2 COG2863 Cytochrome c553; hypothetical protein 1252787 6297011 HPSH_06345 Helicobacter pylori Shi470 hypothetical protein YP_001910701.1 1252497 D 512562 CDS YP_001910702.1 188528015 6297009 1252946..1253419 1 NC_010698.2 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1253419 6297009 HPSH_06350 Helicobacter pylori Shi470 dinucleoside polyphosphate hydrolase YP_001910702.1 1252946 D 512562 CDS YP_001910703.1 188528016 6297008 1253413..1254630 1 NC_010698.2 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1254630 6297008 HPSH_06355 Helicobacter pylori Shi470 aspartate kinase YP_001910703.1 1253413 D 512562 CDS YP_001910704.1 188528017 6297007 1254627..1255169 1 NC_010698.2 hypothetical protein 1255169 6297007 HPSH_06360 Helicobacter pylori Shi470 hypothetical protein YP_001910704.1 1254627 D 512562 CDS YP_001910705.1 188528018 6297006 1255166..1255822 1 NC_010698.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1255822 6297006 HPSH_06365 Helicobacter pylori Shi470 DNA polymerase III subunit delta' YP_001910705.1 1255166 D 512562 CDS YP_001910706.1 188528019 6297004 1255819..1256961 1 NC_010698.2 COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase FolP 1256961 6297004 HPSH_06370 Helicobacter pylori Shi470 dihydropteroate synthase FolP YP_001910706.1 1255819 D 512562 CDS YP_001910707.1 188528020 6297002 complement(1256986..1257447) 1 NC_010698.2 hypothetical protein 1257447 6297002 HPSH_06375 Helicobacter pylori Shi470 hypothetical protein YP_001910707.1 1256986 R 512562 CDS YP_001910708.1 188528021 6297001 1257841..1258737 1 NC_010698.2 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 1258737 6297001 HPSH_06380 Helicobacter pylori Shi470 hypothetical protein YP_001910708.1 1257841 D 512562 CDS YP_001910709.1 188528022 6297000 1258741..1259988 1 NC_010698.2 hypothetical protein 1259988 6297000 HPSH_06385 Helicobacter pylori Shi470 hypothetical protein YP_001910709.1 1258741 D 512562 CDS YP_001910710.1 188528023 6296999 complement(1259985..1260068) 1 NC_010698.2 hypothetical protein 1260068 6296999 HPSH_06390 Helicobacter pylori Shi470 hypothetical protein YP_001910710.1 1259985 R 512562 CDS YP_001910711.1 188528024 6296998 1260067..1260618 1 NC_010698.2 COG2952 Uncharacterized protein conserved in bacteria; hypothetical protein 1260618 6296998 HPSH_06395 Helicobacter pylori Shi470 hypothetical protein YP_001910711.1 1260067 D 512562 CDS YP_001910712.1 188528025 6296997 1260618..1261745 1 NC_010698.2 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1261745 6296997 HPSH_06400 Helicobacter pylori Shi470 carbamoyl phosphate synthase small subunit YP_001910712.1 1260618 D 512562 CDS YP_001910713.1 188528026 6297119 1261913..1262917 1 NC_010698.2 formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 1262917 amiF 6297119 amiF Helicobacter pylori Shi470 formamidase YP_001910713.1 1261913 D 512562 CDS YP_001910714.1 188528027 6296993 complement(1263105..1263206) 1 NC_010698.2 hypothetical protein 1263206 6296993 HPSH_06410 Helicobacter pylori Shi470 hypothetical protein YP_001910714.1 1263105 R 512562 CDS YP_001910715.1 188528028 6296992 complement(1263325..1263897) 1 NC_010698.2 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1263897 6296992 HPSH_06415 Helicobacter pylori Shi470 Maf-like protein YP_001910715.1 1263325 R 512562 CDS YP_001910716.1 188528029 6296991 complement(1263899..1266442) 1 NC_010698.2 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1266442 alaS 6296991 alaS Helicobacter pylori Shi470 alanyl-tRNA synthetase YP_001910716.1 1263899 R 512562 CDS YP_001910717.1 188528030 6296990 1266561..1266791 1 NC_010698.2 COG2841 Uncharacterized protein conserved in bacteria; hypothetical protein 1266791 6296990 HPSH_06425 Helicobacter pylori Shi470 hypothetical protein YP_001910717.1 1266561 D 512562 CDS YP_001910718.1 188528031 6296988 complement(1267051..1267137) 1 NC_010698.2 hypothetical protein 1267137 6296988 HPSH_06430 Helicobacter pylori Shi470 hypothetical protein YP_001910718.1 1267051 R 512562 CDS YP_001910719.1 188528032 6296987 complement(1267137..1267310) 1 NC_010698.2 hypothetical protein 1267310 6296987 HPSH_06435 Helicobacter pylori Shi470 hypothetical protein YP_001910719.1 1267137 R 512562 CDS YP_001910720.1 188528033 6296986 complement(1267314..1269428) 1 NC_010698.2 outer membrane protein 1269428 6296986 HPSH_06440 Helicobacter pylori Shi470 outer membrane protein YP_001910720.1 1267314 R 512562 CDS YP_001910721.1 188528034 6296985 complement(1269923..1270180) 1 NC_010698.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1270180 rpsR 6296985 rpsR Helicobacter pylori Shi470 30S ribosomal protein S18 YP_001910721.1 1269923 R 512562 CDS YP_001910722.1 188528035 6296982 complement(1270203..1270748) 1 NC_010698.2 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1270748 6296982 HPSH_06450 Helicobacter pylori Shi470 single-stranded DNA-binding protein YP_001910722.1 1270203 R 512562 CDS YP_001910723.1 188528036 6296980 complement(1270758..1271186) 1 NC_010698.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1271186 rpsF 6296980 rpsF Helicobacter pylori Shi470 30S ribosomal protein S6 YP_001910723.1 1270758 R 512562 CDS YP_001910724.1 188528037 6296979 complement(1271329..1272351) 1 NC_010698.2 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1272351 6296979 HPSH_06460 Helicobacter pylori Shi470 DNA polymerase III subunit delta YP_001910724.1 1271329 R 512562 CDS YP_001910725.1 188528038 6296978 complement(1272341..1274275) 1 NC_010698.2 COG0557 Exoribonuclease R; 3'-5' exoribonuclease R 1274275 6296978 HPSH_06465 Helicobacter pylori Shi470 3'-5' exoribonuclease R YP_001910725.1 1272341 R 512562 CDS YP_001910726.1 188528039 6296977 complement(1274275..1275066) 1 NC_010698.2 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1275066 aroE 6296977 aroE Helicobacter pylori Shi470 shikimate 5-dehydrogenase YP_001910726.1 1274275 R 512562 CDS YP_001910727.1 188528040 6296975 complement(1275074..1275652) 1 NC_010698.2 hypothetical protein 1275652 6296975 HPSH_06475 Helicobacter pylori Shi470 hypothetical protein YP_001910727.1 1275074 R 512562 CDS YP_001910728.1 188528041 6296974 complement(1276716..1278497) 1 NC_010698.2 COG4166 ABC-type oligopeptide transport system, periplasmic component; hypothetical protein 1278497 6296974 HPSH_06490 Helicobacter pylori Shi470 hypothetical protein YP_001910728.1 1276716 R 512562 CDS YP_001910729.1 188528042 6296973 complement(1278498..1279478) 1 NC_010698.2 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1279478 6296973 HPSH_06495 Helicobacter pylori Shi470 tryptophanyl-tRNA synthetase YP_001910729.1 1278498 R 512562 CDS YP_001910730.1 188528043 6296972 complement(1279550..1280272) 1 NC_010698.2 COG0500 SAM-dependent methyltransferases; biotin synthesis protein BioC 1280272 6296972 HPSH_06500 Helicobacter pylori Shi470 biotin synthesis protein BioC YP_001910730.1 1279550 R 512562 CDS YP_001910731.1 188528044 6296799 1280392..1280991 1 NC_010698.2 COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 1280991 secG 6296799 secG Helicobacter pylori Shi470 preprotein translocase subunit SecG YP_001910731.1 1280392 D 512562 CDS YP_001910732.1 188528045 6297044 1280991..1281548 1 NC_010698.2 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1281548 frr 6297044 frr Helicobacter pylori Shi470 ribosome recycling factor YP_001910732.1 1280991 D 512562 CDS YP_001910733.1 188528046 6296203 1281552..1282157 1 NC_010698.2 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1282157 pyrE 6296203 pyrE Helicobacter pylori Shi470 orotate phosphoribosyltransferase YP_001910733.1 1281552 D 512562 CDS YP_001910734.1 188528047 6296968 1282147..1282611 1 NC_010698.2 COG1714 Predicted membrane protein/domain; hypothetical protein 1282611 6296968 HPSH_06520 Helicobacter pylori Shi470 hypothetical protein YP_001910734.1 1282147 D 512562 CDS YP_001910735.1 188528048 6296967 1282608..1283297 1 NC_010698.2 COG0846 NAD-dependent protein deacetylases, SIR2 family; hypothetical protein 1283297 6296967 HPSH_06525 Helicobacter pylori Shi470 hypothetical protein YP_001910735.1 1282608 D 512562 CDS YP_001910736.1 188528049 6296966 1283399..1283800 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A 1283800 6296966 HPSH_06530 Helicobacter pylori Shi470 NADH dehydrogenase subunit A YP_001910736.1 1283399 D 512562 CDS YP_001910737.1 188528050 6296965 1283800..1284279 1 NC_010698.2 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1284279 6296965 HPSH_06535 Helicobacter pylori Shi470 NADH dehydrogenase subunit B YP_001910737.1 1283800 D 512562 CDS YP_001910738.1 188528051 6296964 1284279..1285076 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C 1285076 6296964 HPSH_06540 Helicobacter pylori Shi470 NADH dehydrogenase subunit C YP_001910738.1 1284279 D 512562 CDS YP_001910739.1 188528052 6296963 1285078..1286307 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1286307 6296963 HPSH_06545 Helicobacter pylori Shi470 NADH dehydrogenase subunit D YP_001910739.1 1285078 D 512562 CDS YP_001910740.1 188528053 6296958 1286304..1286534 1 NC_010698.2 NADH-ubiquinone oxidoreductase subunit E 1286534 6296958 HPSH_06550 Helicobacter pylori Shi470 NADH-ubiquinone oxidoreductase subunit E YP_001910740.1 1286304 D 512562 CDS YP_001910741.1 188528054 6296957 1286531..1287523 1 NC_010698.2 NADH-ubiquinone oxidoreductase subunit F 1287523 6296957 HPSH_06555 Helicobacter pylori Shi470 NADH-ubiquinone oxidoreductase subunit F YP_001910741.1 1286531 D 512562 CDS YP_001910742.1 188528055 6296955 1287520..1290054 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1290054 6296955 HPSH_06560 Helicobacter pylori Shi470 NADH dehydrogenase subunit G YP_001910742.1 1287520 D 512562 CDS YP_001910743.1 188528056 6296954 1290051..1291040 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1291040 6296954 HPSH_06565 Helicobacter pylori Shi470 NADH dehydrogenase subunit H YP_001910743.1 1290051 D 512562 CDS YP_001910744.1 188528057 6296953 1291051..1291713 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1291713 6296953 HPSH_06570 Helicobacter pylori Shi470 NADH dehydrogenase subunit I YP_001910744.1 1291051 D 512562 CDS YP_001910745.1 188528058 6296951 1291706..1292254 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1292254 6296951 HPSH_06575 Helicobacter pylori Shi470 NADH dehydrogenase subunit J YP_001910745.1 1291706 D 512562 CDS YP_001910746.1 188528059 6296950 1292251..1292553 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1292553 6296950 HPSH_06580 Helicobacter pylori Shi470 NADH dehydrogenase subunit K YP_001910746.1 1292251 D 512562 CDS YP_001910747.1 188528060 6296949 1292556..1294394 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1294394 6296949 HPSH_06585 Helicobacter pylori Shi470 NADH dehydrogenase subunit L YP_001910747.1 1292556 D 512562 CDS YP_001910748.1 188528061 6296948 1294398..1295936 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1295936 6296948 HPSH_06590 Helicobacter pylori Shi470 NADH dehydrogenase subunit M YP_001910748.1 1294398 D 512562 CDS YP_001910749.1 188528062 6296947 1295923..1297401 1 NC_010698.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1297401 6296947 HPSH_06595 Helicobacter pylori Shi470 NADH dehydrogenase subunit N YP_001910749.1 1295923 D 512562 CDS YP_001910750.1 188528063 6297016 1297391..1299802 1 NC_010698.2 COG1729 Uncharacterized protein conserved in bacteria; paralysed flagella protein 1299802 6297016 HPSH_06600 Helicobacter pylori Shi470 paralysed flagella protein YP_001910750.1 1297391 D 512562 CDS YP_001910751.1 188528064 6296941 1299804..1301180 1 NC_010698.2 COG1109 Phosphomannomutase; phosphomannomutase 1301180 6296941 HPSH_06605 Helicobacter pylori Shi470 phosphomannomutase YP_001910751.1 1299804 D 512562 CDS YP_001910752.1 188528065 6296940 1301291..1301599 1 NC_010698.2 hypothetical protein 1301599 6296940 HPSH_06610 Helicobacter pylori Shi470 hypothetical protein YP_001910752.1 1301291 D 512562 CDS YP_001910753.1 188528066 6296939 complement(1301830..1302618) 1 NC_010698.2 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1302618 trpA 6296939 trpA Helicobacter pylori Shi470 tryptophan synthase subunit alpha YP_001910753.1 1301830 R 512562 CDS YP_001910754.1 188528067 6296938 complement(1302615..1303796) 1 NC_010698.2 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1303796 6296938 HPSH_06620 Helicobacter pylori Shi470 tryptophan synthase subunit beta YP_001910754.1 1302615 R 512562 CDS YP_001910755.1 188528068 6296937 complement(1303798..1305156) 1 NC_010698.2 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1305156 6296937 HPSH_06625 Helicobacter pylori Shi470 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_001910755.1 1303798 R 512562 CDS YP_001910756.1 188528069 6296934 complement(1305149..1306156) 1 NC_010698.2 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1306156 trpD 6296934 trpD Helicobacter pylori Shi470 anthranilate phosphoribosyltransferase YP_001910756.1 1305149 R 512562 CDS YP_001910757.1 188528070 6296930 complement(1306153..1306737) 1 NC_010698.2 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1306737 6296930 HPSH_06635 Helicobacter pylori Shi470 anthranilate synthase component II YP_001910757.1 1306153 R 512562 CDS YP_001910758.1 188528071 6296929 complement(1306734..1308371) 1 NC_010698.2 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1308371 6296929 HPSH_06640 Helicobacter pylori Shi470 anthranilate synthase component I YP_001910758.1 1306734 R 512562 CDS YP_001910759.1 188528072 6296928 complement(1308325..1309383) 1 NC_010698.2 COG0859 ADP-heptose:LPS heptosyltransferase; hypothetical protein 1309383 6296928 HPSH_06645 Helicobacter pylori Shi470 hypothetical protein YP_001910759.1 1308325 R 512562 CDS YP_001910760.1 188528073 6296922 complement(1309451..1310143) 1 NC_010698.2 COG2503 Predicted secreted acid phosphatase; hypothetical protein 1310143 6296922 HPSH_06650 Helicobacter pylori Shi470 hypothetical protein YP_001910760.1 1309451 R 512562 CDS YP_001910761.1 188528074 6296921 1310313..1310861 1 NC_010698.2 COG2353 Uncharacterized conserved protein; hypothetical protein 1310861 6296921 HPSH_06655 Helicobacter pylori Shi470 hypothetical protein YP_001910761.1 1310313 D 512562 CDS YP_001910762.1 188528075 6296920 complement(1310836..1310973) 1 NC_010698.2 hypothetical protein 1310973 6296920 HPSH_06660 Helicobacter pylori Shi470 hypothetical protein YP_001910762.1 1310836 R 512562 CDS YP_001910763.1 188528076 6296918 1311446..1312102 1 NC_010698.2 COG0819 Putative transcription activator; putative transcriptional regulator 1312102 6296918 HPSH_06665 Helicobacter pylori Shi470 putative transcriptional regulator YP_001910763.1 1311446 D 512562 CDS YP_001910764.1 188528077 6296916 1312224..1312886 1 NC_010698.2 COG3201 Nicotinamide mononucleotide transporter; nicotinamide mononucleotide transporter 1312886 6296916 HPSH_06670 Helicobacter pylori Shi470 nicotinamide mononucleotide transporter YP_001910764.1 1312224 D 512562 CDS YP_001910765.1 188528078 6296915 1312874..1313488 1 NC_010698.2 COG1564 Thiamine pyrophosphokinase; hypothetical protein 1313488 6296915 HPSH_06675 Helicobacter pylori Shi470 hypothetical protein YP_001910765.1 1312874 D 512562 CDS YP_001910766.1 188528079 6296914 1313800..1313952 1 NC_010698.2 hypothetical protein 1313952 6296914 HPSH_06680 Helicobacter pylori Shi470 hypothetical protein YP_001910766.1 1313800 D 512562 CDS YP_001910767.1 188528080 6296892 complement(1313996..1314346) 1 NC_010698.2 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1314346 rplQ 6296892 rplQ Helicobacter pylori Shi470 50S ribosomal protein L17 YP_001910767.1 1313996 R 512562 CDS YP_001910768.1 188528081 6297146 complement(1314346..1315380) 1 NC_010698.2 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1315380 6297146 HPSH_06690 Helicobacter pylori Shi470 DNA-directed RNA polymerase subunit alpha YP_001910768.1 1314346 R 512562 CDS YP_001910769.1 188528082 6297313 complement(1315392..1316018) 1 NC_010698.2 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1316018 rpsD 6297313 rpsD Helicobacter pylori Shi470 30S ribosomal protein S4 YP_001910769.1 1315392 R 512562 CDS YP_001910770.1 188528083 6296912 complement(1316028..1316423) 1 NC_010698.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1316423 6296912 HPSH_06700 Helicobacter pylori Shi470 30S ribosomal protein S11 YP_001910770.1 1316028 R 512562 CDS YP_001910771.1 188528084 6296911 complement(1316446..1316808) 1 NC_010698.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1316808 rpsM 6296911 rpsM Helicobacter pylori Shi470 30S ribosomal protein S13 YP_001910771.1 1316446 R 512562 CDS YP_001910772.1 188528085 6296910 complement(1316812..1316925) 1 NC_010698.2 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1316925 rpmJ 6296910 rpmJ Helicobacter pylori Shi470 50S ribosomal protein L36 YP_001910772.1 1316812 R 512562 CDS YP_001910773.1 188528086 6296909 complement(1317004..1317222) 1 NC_010698.2 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1317222 infA 6296909 infA Helicobacter pylori Shi470 translation initiation factor IF-1 YP_001910773.1 1317004 R 512562 CDS YP_001910774.1 188528087 6296908 complement(1317222..1317983) 1 NC_010698.2 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1317983 6296908 HPSH_06720 Helicobacter pylori Shi470 methionine aminopeptidase YP_001910774.1 1317222 R 512562 CDS YP_001910775.1 188528088 6296907 complement(1317983..1319245) 1 NC_010698.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1319245 secY 6296907 secY Helicobacter pylori Shi470 preprotein translocase subunit SecY YP_001910775.1 1317983 R 512562 CDS YP_001910776.1 188528089 6296906 complement(1319283..1319684) 1 NC_010698.2 late assembly protein; 50S ribosomal protein L15 1319684 rplO 6296906 rplO Helicobacter pylori Shi470 50S ribosomal protein L15 YP_001910776.1 1319283 R 512562 CDS YP_001910777.1 188528090 6296905 complement(1319702..1320163) 1 NC_010698.2 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1320163 rpsE 6296905 rpsE Helicobacter pylori Shi470 30S ribosomal protein S5 YP_001910777.1 1319702 R 512562 CDS YP_001910778.1 188528091 6296904 complement(1320160..1320516) 1 NC_010698.2 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1320516 rplR 6296904 rplR Helicobacter pylori Shi470 50S ribosomal protein L18 YP_001910778.1 1320160 R 512562 CDS YP_001910779.1 188528092 6296901 complement(1320530..1321066) 1 NC_010698.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1321066 rplF 6296901 rplF Helicobacter pylori Shi470 50S ribosomal protein L6 YP_001910779.1 1320530 R 512562 CDS YP_001910780.1 188528093 6296900 complement(1321077..1321472) 1 NC_010698.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1321472 rpsH 6296900 rpsH Helicobacter pylori Shi470 30S ribosomal protein S8 YP_001910780.1 1321077 R 512562 CDS YP_001910781.1 188528094 6296899 complement(1321482..1321667) 1 NC_010698.2 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 1321667 rpsN 6296899 rpsN Helicobacter pylori Shi470 30S ribosomal protein S14 YP_001910781.1 1321482 R 512562 CDS YP_001910782.1 188528095 6296897 complement(1321677..1322222) 1 NC_010698.2 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1322222 rplE 6296897 rplE Helicobacter pylori Shi470 50S ribosomal protein L5 YP_001910782.1 1321677 R 512562 CDS YP_001910783.1 188528096 6296896 complement(1322235..1322456) 1 NC_010698.2 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1322456 rplX 6296896 rplX Helicobacter pylori Shi470 50S ribosomal protein L24 YP_001910783.1 1322235 R 512562 CDS YP_001910784.1 188528097 6296894 complement(1322456..1322824) 1 NC_010698.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1322824 rplN 6296894 rplN Helicobacter pylori Shi470 50S ribosomal protein L14 YP_001910784.1 1322456 R 512562 CDS YP_001910785.1 188528098 6296893 complement(1322827..1323087) 1 NC_010698.2 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1323087 rpsQ 6296893 rpsQ Helicobacter pylori Shi470 30S ribosomal protein S17 YP_001910785.1 1322827 R 512562 CDS YP_001910786.1 188528099 6296913 complement(1323101..1323301) 1 NC_010698.2 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1323301 6296913 HPSH_06780 Helicobacter pylori Shi470 50S ribosomal protein L29 YP_001910786.1 1323101 R 512562 CDS YP_001910787.1 188528100 6296888 complement(1323288..1323713) 1 NC_010698.2 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1323713 rplP 6296888 rplP Helicobacter pylori Shi470 50S ribosomal protein L16 YP_001910787.1 1323288 R 512562 CDS YP_001910788.1 188528101 6296887 complement(1323716..1324420) 1 NC_010698.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1324420 rpsC 6296887 rpsC Helicobacter pylori Shi470 30S ribosomal protein S3 YP_001910788.1 1323716 R 512562 CDS YP_001910789.1 188528102 6296886 complement(1324424..1324792) 1 NC_010698.2 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1324792 rplV 6296886 rplV Helicobacter pylori Shi470 50S ribosomal protein L22 YP_001910789.1 1324424 R 512562 CDS YP_001910790.1 188528103 6296885 complement(1324802..1325083) 1 NC_010698.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1325083 rpsS 6296885 rpsS Helicobacter pylori Shi470 30S ribosomal protein S19 YP_001910790.1 1324802 R 512562 CDS YP_001910791.1 188528104 6296884 complement(1325087..1325923) 1 NC_010698.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1325923 rplB 6296884 rplB Helicobacter pylori Shi470 50S ribosomal protein L2 YP_001910791.1 1325087 R 512562 CDS YP_001910792.1 188528105 6296883 complement(1325939..1326220) 1 NC_010698.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1326220 rplW 6296883 rplW Helicobacter pylori Shi470 50S ribosomal protein L23 YP_001910792.1 1325939 R 512562 CDS YP_001910793.1 188528106 6296882 complement(1326224..1326871) 1 NC_010698.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1326871 rplD 6296882 rplD Helicobacter pylori Shi470 50S ribosomal protein L4 YP_001910793.1 1326224 R 512562 CDS YP_001910794.1 188528107 6296881 complement(1326906..1327481) 1 NC_010698.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1327481 rplC 6296881 rplC Helicobacter pylori Shi470 50S ribosomal protein L3 YP_001910794.1 1326906 R 512562 CDS YP_001910795.1 188528108 6296880 complement(1327518..1327832) 1 NC_010698.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1327832 rpsJ 6296880 rpsJ Helicobacter pylori Shi470 30S ribosomal protein S10 YP_001910795.1 1327518 R 512562 CDS YP_001910796.1 188528109 6296879 1327987..1329120 1 NC_010698.2 COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; ATP-binding protein 1329120 6296879 HPSH_06830 Helicobacter pylori Shi470 ATP-binding protein YP_001910796.1 1327987 D 512562 CDS YP_001910797.1 188528110 6296878 1329340..1329921 1 NC_010698.2 hypothetical protein 1329921 6296878 HPSH_06835 Helicobacter pylori Shi470 hypothetical protein YP_001910797.1 1329340 D 512562 CDS YP_001910798.1 188528111 6296877 complement(1329895..1330509) 1 NC_010698.2 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1330509 rnhB 6296877 rnhB Helicobacter pylori Shi470 ribonuclease HII YP_001910798.1 1329895 R 512562 CDS YP_001910799.1 188528112 6296875 complement(1330540..1330770) 1 NC_010698.2 hypothetical protein 1330770 6296875 HPSH_06845 Helicobacter pylori Shi470 hypothetical protein YP_001910799.1 1330540 R 512562 CDS YP_001910800.1 188528113 6296873 complement(1330793..1332184) 1 NC_010698.2 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1332184 fumC 6296873 fumC Helicobacter pylori Shi470 fumarate hydratase YP_001910800.1 1330793 R 512562 CDS YP_001910801.1 188528114 6296872 1332359..1332736 1 NC_010698.2 hypothetical protein 1332736 6296872 HPSH_06855 Helicobacter pylori Shi470 hypothetical protein YP_001910801.1 1332359 D 512562 CDS YP_001910802.1 188528115 6296871 1332792..1333979 1 NC_010698.2 hypothetical protein 1333979 6296871 HPSH_06860 Helicobacter pylori Shi470 hypothetical protein YP_001910802.1 1332792 D 512562 CDS YP_001910803.1 188528116 6296870 1333976..1334983 1 NC_010698.2 COG0845 Membrane-fusion protein; cation efflux system protein CzcA 1334983 6296870 HPSH_06865 Helicobacter pylori Shi470 cation efflux system protein CzcA YP_001910803.1 1333976 D 512562 CDS YP_001910804.1 188528117 6296759 1334984..1338097 1 NC_010698.2 COG3696 Putative silver efflux pump; cation efflux system protein CzcA 1338097 6296759 HPSH_06870 Helicobacter pylori Shi470 cation efflux system protein CzcA YP_001910804.1 1334984 D 512562 CDS YP_001910805.1 188528118 6296994 complement(1338094..1338441) 1 NC_010698.2 COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance); hypothetical protein 1338441 6296994 HPSH_06875 Helicobacter pylori Shi470 hypothetical protein YP_001910805.1 1338094 R 512562 CDS YP_001910806.1 188528119 6296104 complement(1338435..1339121) 1 NC_010698.2 COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); branched-chain amino acid transport protein 1339121 6296104 HPSH_06880 Helicobacter pylori Shi470 branched-chain amino acid transport protein YP_001910806.1 1338435 R 512562 CDS YP_001910807.1 188528120 6296867 complement(1339132..1340241) 1 NC_010698.2 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1340241 6296867 HPSH_06885 Helicobacter pylori Shi470 chaperone protein DnaJ YP_001910807.1 1339132 R 512562 CDS YP_001910808.1 188528121 6296864 1340420..1341496 1 NC_010698.2 hypothetical protein 1341496 6296864 HPSH_06890 Helicobacter pylori Shi470 hypothetical protein YP_001910808.1 1340420 D 512562 CDS YP_001910809.1 188528122 6296861 1341698..1341811 1 NC_010698.2 hypothetical protein 1341811 6296861 HPSH_06895 Helicobacter pylori Shi470 hypothetical protein YP_001910809.1 1341698 D 512562 CDS YP_001910810.1 188528123 6296860 1342021..1342386 1 NC_010698.2 COG1432 Uncharacterized conserved protein; hypothetical protein 1342386 6296860 HPSH_06900 Helicobacter pylori Shi470 hypothetical protein YP_001910810.1 1342021 D 512562 CDS YP_001910811.1 188528124 6296858 complement(1342447..1343475) 1 NC_010698.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1343475 mnmA 6296858 mnmA Helicobacter pylori Shi470 tRNA-specific 2-thiouridylase MnmA YP_001910811.1 1342447 R 512562 CDS YP_001910812.1 188528125 6296857 1343616..1344377 1 NC_010698.2 COG2214 DnaJ-class molecular chaperone; hypothetical protein 1344377 6296857 HPSH_06910 Helicobacter pylori Shi470 hypothetical protein YP_001910812.1 1343616 D 512562 CDS YP_001910813.1 188528126 6296854 complement(1344374..1344889) 1 NC_010698.2 COG1057 Nicotinic acid mononucleotide adenylyltransferase; hypothetical protein 1344889 6296854 HPSH_06915 Helicobacter pylori Shi470 hypothetical protein YP_001910813.1 1344374 R 512562 CDS YP_001910814.1 188528127 6296853 complement(1344882..1345328) 1 NC_010698.2 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 1345328 6296853 HPSH_06920 Helicobacter pylori Shi470 nickel responsive regulator YP_001910814.1 1344882 R 512562 CDS YP_001910815.1 188528128 6296852 1345665..1346102 1 NC_010698.2 COG0811 Biopolymer transport proteins; biopolymer transport protein ExbB 1346102 6296852 HPSH_06925 Helicobacter pylori Shi470 biopolymer transport protein ExbB YP_001910815.1 1345665 D 512562 CDS YP_001910816.1 188528129 6296851 1346099..1346488 1 NC_010698.2 COG0848 Biopolymer transport protein; biopolymer transport protein 1346488 6296851 HPSH_06930 Helicobacter pylori Shi470 biopolymer transport protein YP_001910816.1 1346099 D 512562 CDS YP_001910817.1 188528130 6296850 1346454..1347308 1 NC_010698.2 COG0810 Periplasmic protein TonB, links inner and outer membranes; siderophore-mediated iron transport protein TonB 1347308 6296850 HPSH_06935 Helicobacter pylori Shi470 siderophore-mediated iron transport protein TonB YP_001910817.1 1346454 D 512562 CDS YP_001910818.1 188528131 6296849 complement(1347973..1348701) 1 NC_010698.2 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 1348701 6296849 HPSH_06950 Helicobacter pylori Shi470 hypothetical protein YP_001910818.1 1347973 R 512562 CDS YP_001910819.1 188528132 6296848 complement(1348708..1349664) 1 NC_010698.2 COG0598 Mg2+ and Co2+ transporters; magnesium and cobalt transport protein 1349664 6296848 HPSH_06955 Helicobacter pylori Shi470 magnesium and cobalt transport protein YP_001910819.1 1348708 R 512562 CDS YP_001910820.1 188528133 6296847 complement(1349680..1350888) 1 NC_010698.2 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1350888 pgk 6296847 pgk Helicobacter pylori Shi470 phosphoglycerate kinase YP_001910820.1 1349680 R 512562 CDS YP_001910821.1 188528134 6296844 complement(1350904..1351896) 1 NC_010698.2 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 1351896 6296844 HPSH_06965 Helicobacter pylori Shi470 glyceraldehyde-3-phosphate dehydrogenase YP_001910821.1 1350904 R 512562 CDS YP_001910822.1 188528135 6297062 complement(1351985..1352686) 1 NC_010698.2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1352686 6297062 HPSH_06970 Helicobacter pylori Shi470 uracil-DNA glycosylase YP_001910822.1 1351985 R 512562 CDS YP_001910823.1 188528136 6296838 complement(1352683..1353405) 1 NC_010698.2 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-glycerol-3-phosphate acyltransferase 1353405 6296838 HPSH_06975 Helicobacter pylori Shi470 1-acyl-glycerol-3-phosphate acyltransferase YP_001910823.1 1352683 R 512562 CDS YP_001910824.1 188528137 6296837 complement(1353392..1354555) 1 NC_010698.2 hypothetical protein 1354555 6296837 HPSH_06980 Helicobacter pylori Shi470 hypothetical protein YP_001910824.1 1353392 R 512562 CDS YP_001910825.1 188528138 6296836 complement(1354562..1355926) 1 NC_010698.2 COG0793 Periplasmic protease; protease 1355926 6296836 HPSH_06985 Helicobacter pylori Shi470 protease YP_001910825.1 1354562 R 512562 CDS YP_001910826.1 188528139 6296835 complement(1356037..1356270) 1 NC_010698.2 adenine specific DNA methyltransferase 1356270 6296835 HPSH_06990 Helicobacter pylori Shi470 adenine specific DNA methyltransferase YP_001910826.1 1356037 R 512562 CDS YP_001910827.1 188528140 6296834 complement(1356335..1357228) 1 NC_010698.2 hypothetical protein 1357228 6296834 HPSH_06995 Helicobacter pylori Shi470 hypothetical protein YP_001910827.1 1356335 R 512562 CDS YP_001910828.1 188528141 6296833 complement(1357228..1358307) 1 NC_010698.2 COG0863 DNA modification methylase; adenine specific DNA methyltransferase 1358307 6296833 HPSH_07000 Helicobacter pylori Shi470 adenine specific DNA methyltransferase YP_001910828.1 1357228 R 512562 CDS YP_001910829.1 188528142 6296832 complement(1358427..1358654) 1 NC_010698.2 adenine specific DNA methyltransferase 1358654 6296832 HPSH_07005 Helicobacter pylori Shi470 adenine specific DNA methyltransferase YP_001910829.1 1358427 R 512562 CDS YP_001910830.1 188528143 6296831 complement(1358699..1361935) 1 NC_010698.2 COG4889 Predicted helicase; hypothetical protein 1361935 6296831 HPSH_07010 Helicobacter pylori Shi470 hypothetical protein YP_001910830.1 1358699 R 512562 CDS YP_001910831.1 188528144 6296830 complement(1361959..1362780) 1 NC_010698.2 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1362780 6296830 HPSH_07015 Helicobacter pylori Shi470 nicotinate-nucleotide pyrophosphorylase YP_001910831.1 1361959 R 512562 CDS YP_001910832.1 188528145 6296829 complement(1362780..1363790) 1 NC_010698.2 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1363790 6296829 HPSH_07020 Helicobacter pylori Shi470 quinolinate synthetase YP_001910832.1 1362780 R 512562 CDS YP_001910833.1 188528146 6296828 complement(1363780..1364583) 1 NC_010698.2 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 1364583 6296828 HPSH_07025 Helicobacter pylori Shi470 phosphatidylserine decarboxylase YP_001910833.1 1363780 R 512562 CDS YP_001910834.1 188528147 6296827 complement(1364580..1365083) 1 NC_010698.2 hypothetical protein 1365083 6296827 HPSH_07030 Helicobacter pylori Shi470 hypothetical protein YP_001910834.1 1364580 R 512562 CDS YP_001910835.1 188528148 6296826 complement(1365096..1365590) 1 NC_010698.2 hypothetical protein 1365590 6296826 HPSH_07035 Helicobacter pylori Shi470 hypothetical protein YP_001910835.1 1365096 R 512562 CDS YP_001910836.1 188528149 6296825 complement(1365583..1366467) 1 NC_010698.2 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 1366467 ubiA 6296825 ubiA Helicobacter pylori Shi470 prenyltransferase YP_001910836.1 1365583 R 512562 CDS YP_001910837.1 188528150 6296824 complement(1366496..1367809) 1 NC_010698.2 COG0658 Predicted membrane metal-binding protein; competence locus E 1367809 6296824 HPSH_07045 Helicobacter pylori Shi470 competence locus E YP_001910837.1 1366496 R 512562 CDS YP_001910838.1 188528151 6296823 complement(1367806..1369272) 1 NC_010698.2 unwinds double stranded DNA; replicative DNA helicase 1369272 6296823 HPSH_07050 Helicobacter pylori Shi470 replicative DNA helicase YP_001910838.1 1367806 R 512562 CDS YP_001910839.1 188528152 6296635 complement(1369283..1370677) 1 NC_010698.2 COG0062 Uncharacterized conserved protein; hypothetical protein 1370677 6296635 HPSH_07055 Helicobacter pylori Shi470 hypothetical protein YP_001910839.1 1369283 R 512562 CDS YP_001910840.1 188528153 6296839 complement(1370680..1371813) 1 NC_010698.2 COG0642 Signal transduction histidine kinase; signal-transducing protein, histidine kinase 1371813 6296839 HPSH_07060 Helicobacter pylori Shi470 signal-transducing protein, histidine kinase YP_001910840.1 1370680 R 512562 CDS YP_001910841.1 188528154 6296164 complement(1371848..1372489) 1 NC_010698.2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative transcriptional regulator 1372489 6296164 HPSH_07065 Helicobacter pylori Shi470 putative transcriptional regulator YP_001910841.1 1371848 R 512562 CDS YP_001910842.1 188528155 6296821 complement(1372577..1373635) 1 NC_010698.2 type IIS restriction enzyme R protein 1373635 6296821 HPSH_07070 Helicobacter pylori Shi470 type IIS restriction enzyme R protein YP_001910842.1 1372577 R 512562 CDS YP_001910843.1 188528156 6296819 1373810..1374652 1 NC_010698.2 type II restriction endonuclease 1374652 6296819 HPSH_07075 Helicobacter pylori Shi470 type II restriction endonuclease YP_001910843.1 1373810 D 512562 CDS YP_001910844.1 188528157 6296817 1374652..1375545 1 NC_010698.2 COG0338 Site-specific DNA methylase; adenine-specific DNA metylase 1375545 6296817 HPSH_07080 Helicobacter pylori Shi470 adenine-specific DNA metylase YP_001910844.1 1374652 D 512562 CDS YP_001910845.1 188528158 6296816 1375517..1376959 1 NC_010698.2 COG2189 Adenine specific DNA methylase Mod; adenine-specific DNA methylase 1376959 6296816 HPSH_07085 Helicobacter pylori Shi470 adenine-specific DNA methylase YP_001910845.1 1375517 D 512562 CDS YP_001910846.1 188528159 6296815 1376917..1377993 1 NC_010698.2 COG2189 Adenine specific DNA methylase Mod; adenine-specific DNA methylase 1377993 6296815 HPSH_07090 Helicobacter pylori Shi470 adenine-specific DNA methylase YP_001910846.1 1376917 D 512562 CDS YP_001910847.1 188528160 6296814 1378003..1380915 1 NC_010698.2 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type III restriction enzyme R protein 1380915 6296814 HPSH_07095 Helicobacter pylori Shi470 type III restriction enzyme R protein YP_001910847.1 1378003 D 512562 CDS YP_001910848.1 188528161 6296813 complement(1380965..1381711) 1 NC_010698.2 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1381711 6296813 HPSH_07100 Helicobacter pylori Shi470 rod shape-determining protein MreC YP_001910848.1 1380965 R 512562 CDS YP_001910849.1 188528162 6296812 complement(1381715..1382758) 1 NC_010698.2 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1382758 6296812 HPSH_07105 Helicobacter pylori Shi470 rod shape-determining protein MreB YP_001910849.1 1381715 R 512562 CDS YP_001910850.1 188528163 6296810 complement(1382801..1384147) 1 NC_010698.2 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1384147 clpX 6296810 clpX Helicobacter pylori Shi470 ATP-dependent protease ATP-binding subunit ClpX YP_001910850.1 1382801 R 512562 CDS YP_001910851.1 188528164 6296809 complement(1384149..1384961) 1 NC_010698.2 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1384961 6296809 HPSH_07115 Helicobacter pylori Shi470 UDP-N-acetylglucosamine acyltransferase YP_001910851.1 1384149 R 512562 CDS YP_001910852.1 188528165 6296808 complement(1384964..1385443) 1 NC_010698.2 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1385443 fabZ 6296808 fabZ Helicobacter pylori Shi470 (3R)-hydroxymyristoyl-ACP dehydratase YP_001910852.1 1384964 R 512562 CDS YP_001910853.1 188528166 6296806 complement(1385626..1386015) 1 NC_010698.2 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1386015 6296806 HPSH_07125 Helicobacter pylori Shi470 flagellar assembly protein FliW YP_001910853.1 1385626 R 512562 CDS YP_001910854.1 188528167 6296805 1386232..1386378 1 NC_010698.2 hypothetical protein 1386378 6296805 HPSH_07130 Helicobacter pylori Shi470 hypothetical protein YP_001910854.1 1386232 D 512562 CDS YP_001910855.1 188528168 6296804 1386421..1387083 1 NC_010698.2 COG4105 DNA uptake lipoprotein; competence lipoprotein 1387083 6296804 HPSH_07135 Helicobacter pylori Shi470 competence lipoprotein YP_001910855.1 1386421 D 512562 CDS YP_001910856.1 188528169 6296803 1387124..1389592 1 NC_010698.2 COG0466 ATP-dependent Lon protease, bacterial type; ATP-dependent protease 1389592 6296803 HPSH_07140 Helicobacter pylori Shi470 ATP-dependent protease YP_001910856.1 1387124 D 512562 CDS YP_001910857.1 188528170 6296802 1389601..1390428 1 NC_010698.2 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1390428 6296802 HPSH_07145 Helicobacter pylori Shi470 prephenate dehydrogenase YP_001910857.1 1389601 D 512562 CDS YP_001910858.1 188528171 6296801 complement(1390714..1391562) 1 NC_010698.2 COG1864 DNA/RNA endonuclease G, NUC1; putative endonuclease 1391562 6296801 HPSH_07150 Helicobacter pylori Shi470 putative endonuclease YP_001910858.1 1390714 R 512562 CDS YP_001910859.1 188528172 6296970 complement(1391687..1393405) 1 NC_010698.2 COG2189 Adenine specific DNA methylase Mod; putative type III restriction enzyme M protein 1393405 6296970 HPSH_07155 Helicobacter pylori Shi470 putative type III restriction enzyme M protein YP_001910859.1 1391687 R 512562 CDS YP_001910860.1 188528173 6296797 1396155..1397003 1 NC_010698.2 catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1397003 6296797 HPSH_07170 Helicobacter pylori Shi470 biotin synthase YP_001910860.1 1396155 D 512562 CDS YP_001910861.1 188528174 6296796 1397003..1397881 1 NC_010698.2 COG1295 Predicted membrane protein; putative ribonuclease N 1397881 6296796 HPSH_07175 Helicobacter pylori Shi470 putative ribonuclease N YP_001910861.1 1397003 D 512562 CDS YP_001910862.1 188528175 6296793 complement(1402463..1402729) 1 NC_010698.2 hypothetical protein 1402729 6296793 HPSH_07180 Helicobacter pylori Shi470 hypothetical protein YP_001910862.1 1402463 R 512562 CDS YP_001910863.1 188528176 6296792 complement(1403060..1404400) 1 NC_010698.2 hypothetical protein 1404400 6296792 HPSH_07185 Helicobacter pylori Shi470 hypothetical protein YP_001910863.1 1403060 R 512562 CDS YP_001910864.1 188528177 6296791 complement(1404416..1404778) 1 NC_010698.2 hypothetical protein 1404778 6296791 HPSH_07190 Helicobacter pylori Shi470 hypothetical protein YP_001910864.1 1404416 R 512562 CDS YP_001910865.1 188528178 6296790 complement(1404799..1405491) 1 NC_010698.2 hypothetical protein 1405491 6296790 HPSH_07195 Helicobacter pylori Shi470 hypothetical protein YP_001910865.1 1404799 R 512562 CDS YP_001910866.1 188528179 6296789 complement(1405754..1406194) 1 NC_010698.2 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1406194 6296789 HPSH_07200 Helicobacter pylori Shi470 7-cyano-7-deazaguanine reductase YP_001910866.1 1405754 R 512562 CDS YP_001910867.1 188528180 6296788 1406253..1406594 1 NC_010698.2 COG0799 Uncharacterized homolog of plant Iojap protein; hypothetical protein 1406594 6296788 HPSH_07205 Helicobacter pylori Shi470 hypothetical protein YP_001910867.1 1406253 D 512562 CDS YP_001910868.1 188528181 6296787 1406665..1407495 1 NC_010698.2 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1407495 miaA 6296787 miaA Helicobacter pylori Shi470 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001910868.1 1406665 D 512562 CDS YP_001910869.1 188528182 6296786 1407500..1408603 1 NC_010698.2 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glucosyltransferase 1408603 6296786 HPSH_07215 Helicobacter pylori Shi470 lipopolysaccharide 1,2-glucosyltransferase YP_001910869.1 1407500 D 512562 CDS YP_001910870.1 188528183 6296785 complement(1410160..1410939) 1 NC_010698.2 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1410939 murB 6296785 murB Helicobacter pylori Shi470 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001910870.1 1410160 R 512562 CDS YP_001910871.1 188528184 6296784 complement(1410943..1411194) 1 NC_010698.2 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1411194 fliQ 6296784 fliQ Helicobacter pylori Shi470 flagellar biosynthesis protein FliQ YP_001910871.1 1410943 R 512562 CDS YP_001910872.1 188528185 6296714 complement(1411220..1412524) 1 NC_010698.2 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1412524 fliI 6296714 fliI Helicobacter pylori Shi470 flagellum-specific ATP synthase YP_001910872.1 1411220 R 512562 CDS YP_001910873.1 188528186 6296942 complement(1412525..1413439) 1 NC_010698.2 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; type IV secretion system ATPase 1413439 6296942 HPSH_07250 Helicobacter pylori Shi470 type IV secretion system ATPase YP_001910873.1 1412525 R 512562 CDS YP_001910874.1 188528187 6296355 complement(1413456..1416218) 1 NC_010698.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1416218 ileS 6296355 ileS Helicobacter pylori Shi470 isoleucyl-tRNA synthetase YP_001910874.1 1413456 R 512562 CDS YP_001910875.1 188528188 6296782 complement(1416253..1416510) 1 NC_010698.2 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); hypothetical protein 1416510 6296782 HPSH_07260 Helicobacter pylori Shi470 hypothetical protein YP_001910875.1 1416253 R 512562 CDS YP_001910876.1 188528189 6296781 1416612..1417232 1 NC_010698.2 hypothetical protein 1417232 6296781 HPSH_07265 Helicobacter pylori Shi470 hypothetical protein YP_001910876.1 1416612 D 512562 CDS YP_001910877.1 188528190 6296780 complement(1417498..1417752) 1 NC_010698.2 hypothetical protein 1417752 6296780 HPSH_07270 Helicobacter pylori Shi470 hypothetical protein YP_001910877.1 1417498 R 512562 CDS YP_001910878.1 188528191 6296779 complement(1417939..1419012) 1 NC_010698.2 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1419012 6296779 HPSH_07275 Helicobacter pylori Shi470 ribosomal RNA large subunit methyltransferase N YP_001910878.1 1417939 R 512562 CDS YP_001910879.1 188528192 6296778 complement(1419009..1419998) 1 NC_010698.2 COG0794 Predicted sugar phosphate isomerase involved in capsule formation; polysialic acid capsule expression protein KpsF 1419998 6296778 HPSH_07280 Helicobacter pylori Shi470 polysialic acid capsule expression protein KpsF YP_001910879.1 1419009 R 512562 CDS YP_001910880.1 188528193 6296777 complement(1419982..1422075) 1 NC_010698.2 COG1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain; ATP-binding protein 1422075 6296777 HPSH_07285 Helicobacter pylori Shi470 ATP-binding protein YP_001910880.1 1419982 R 512562 CDS YP_001910881.1 188528194 6296776 complement(1422109..1422924) 1 NC_010698.2 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1422924 ksgA 6296776 ksgA Helicobacter pylori Shi470 dimethyladenosine transferase YP_001910881.1 1422109 R 512562 CDS YP_001910882.1 188528195 6296775 1423717..1423809 1 NC_010698.2 hypothetical protein 1423809 6296775 HPSH_07295 Helicobacter pylori Shi470 hypothetical protein YP_001910882.1 1423717 D 512562 CDS YP_001910883.1 188528196 6296774 complement(1423889..1424998) 1 NC_010698.2 COG0732 Restriction endonuclease S subunits; type I R-M system specificity subunit 1424998 6296774 HPSH_07300 Helicobacter pylori Shi470 type I R-M system specificity subunit YP_001910883.1 1423889 R 512562 CDS YP_001910884.1 188528197 6296773 complement(1425011..1425892) 1 NC_010698.2 COG0788 Formyltetrahydrofolate hydrolase; formyltetrahydrofolate hydrolase PurU 1425892 6296773 HPSH_07305 Helicobacter pylori Shi470 formyltetrahydrofolate hydrolase PurU YP_001910884.1 1425011 R 512562 CDS YP_001910885.1 188528198 6296772 complement(1425895..1426773) 1 NC_010698.2 COG0616 Periplasmic serine proteases (ClpP class); protease IV PspA 1426773 6296772 HPSH_07310 Helicobacter pylori Shi470 protease IV PspA YP_001910885.1 1425895 R 512562 CDS YP_001910886.1 188528199 6296768 1426844..1427116 1 NC_010698.2 hypothetical protein 1427116 6296768 HPSH_07315 Helicobacter pylori Shi470 hypothetical protein YP_001910886.1 1426844 D 512562 CDS YP_001910887.1 188528200 6296767 complement(1427160..1427324) 1 NC_010698.2 hypothetical protein 1427324 6296767 HPSH_07320 Helicobacter pylori Shi470 hypothetical protein YP_001910887.1 1427160 R 512562 CDS YP_001910888.1 188528201 6296764 1427349..1428023 1 NC_010698.2 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein 1428023 6296764 HPSH_07325 Helicobacter pylori Shi470 hypothetical protein YP_001910888.1 1427349 D 512562 CDS YP_001910889.1 188528202 6296763 1428032..1428319 1 NC_010698.2 hypothetical protein 1428319 6296763 HPSH_07330 Helicobacter pylori Shi470 hypothetical protein YP_001910889.1 1428032 D 512562 CDS YP_001910890.1 188528203 6296762 1428309..1428470 1 NC_010698.2 hypothetical protein 1428470 6296762 HPSH_07335 Helicobacter pylori Shi470 hypothetical protein YP_001910890.1 1428309 D 512562 CDS YP_001910891.1 188528204 6296869 complement(1428489..1428962) 1 NC_010698.2 hypothetical protein 1428962 6296869 HPSH_07340 Helicobacter pylori Shi470 hypothetical protein YP_001910891.1 1428489 R 512562 CDS YP_001910892.1 188528205 6296757 1428967..1429149 1 NC_010698.2 hypothetical protein 1429149 6296757 HPSH_07345 Helicobacter pylori Shi470 hypothetical protein YP_001910892.1 1428967 D 512562 CDS YP_001910893.1 188528206 6296756 1429495..1429797 1 NC_010698.2 COG3676 Transposase and inactivated derivatives; hypothetical protein 1429797 6296756 HPSH_07350 Helicobacter pylori Shi470 hypothetical protein YP_001910893.1 1429495 D 512562 CDS YP_001910894.1 188528207 6296755 1429816..1430352 1 NC_010698.2 hypothetical protein 1430352 6296755 HPSH_07355 Helicobacter pylori Shi470 hypothetical protein YP_001910894.1 1429816 D 512562 CDS YP_001910895.1 188528208 6296754 1430336..1430443 1 NC_010698.2 hypothetical protein 1430443 6296754 HPSH_07360 Helicobacter pylori Shi470 hypothetical protein YP_001910895.1 1430336 D 512562 CDS YP_001910896.1 188528209 6296753 complement(1430830..1430925) 1 NC_010698.2 hypothetical protein 1430925 6296753 HPSH_07365 Helicobacter pylori Shi470 hypothetical protein YP_001910896.1 1430830 R 512562 CDS YP_001910897.1 188528210 6296750 complement(1432988..1433767) 1 NC_010698.2 hypothetical protein 1433767 6296750 HPSH_07370 Helicobacter pylori Shi470 hypothetical protein YP_001910897.1 1432988 R 512562 CDS YP_001910898.1 188528211 6296749 1433891..1434379 1 NC_010698.2 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase B 1434379 6296749 HPSH_07375 Helicobacter pylori Shi470 peptidyl-prolyl cis-trans isomerase B YP_001910898.1 1433891 D 512562 CDS YP_001910899.1 188528212 6296747 1434397..1434627 1 NC_010698.2 affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator 1434627 6296747 HPSH_07380 Helicobacter pylori Shi470 carbon storage regulator YP_001910899.1 1434397 D 512562 CDS YP_001910900.1 188528213 6296746 1434627..1435430 1 NC_010698.2 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1435430 6296746 HPSH_07385 Helicobacter pylori Shi470 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001910900.1 1434627 D 512562 CDS YP_001910901.1 188528214 6296745 1435427..1435885 1 NC_010698.2 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1435885 smpB 6296745 smpB Helicobacter pylori Shi470 SsrA-binding protein YP_001910901.1 1435427 D 512562 CDS YP_001910902.1 188528215 6296744 1435888..1436340 1 NC_010698.2 COG0811 Biopolymer transport proteins; biopolymer transport protein 1436340 6296744 HPSH_07395 Helicobacter pylori Shi470 biopolymer transport protein YP_001910902.1 1435888 D 512562 CDS YP_001910903.1 188528216 6296743 1436351..1436752 1 NC_010698.2 COG0848 Biopolymer transport protein; biopolymer transport protein 1436752 6296743 HPSH_07400 Helicobacter pylori Shi470 biopolymer transport protein YP_001910903.1 1436351 D 512562 CDS YP_001910904.1 188528217 6296741 1436826..1436960 1 NC_010698.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1436960 rpmH 6296741 rpmH Helicobacter pylori Shi470 50S ribosomal protein L34 YP_001910904.1 1436826 D 512562 CDS YP_001910905.1 188528218 6296739 1436920..1437405 1 NC_010698.2 COG0594 RNase P protein component; ribonuclease P, protein component RnpA 1437405 6296739 HPSH_07410 Helicobacter pylori Shi470 ribonuclease P, protein component RnpA YP_001910905.1 1436920 D 512562 CDS YP_001910906.1 188528219 6296590 1437392..1437748 1 NC_010698.2 COG0759 Uncharacterized conserved protein; hypothetical protein 1437748 6296590 HPSH_07415 Helicobacter pylori Shi470 hypothetical protein YP_001910906.1 1437392 D 512562 CDS YP_001910907.1 188528220 6296798 1437754..1439394 1 NC_010698.2 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 1439394 6296798 HPSH_07420 Helicobacter pylori Shi470 putative inner membrane protein translocase component YidC YP_001910907.1 1437754 D 512562 CDS YP_001910908.1 188528221 6297405 1439394..1440191 1 NC_010698.2 COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain; hypothetical protein 1440191 6297405 HPSH_07425 Helicobacter pylori Shi470 hypothetical protein YP_001910908.1 1439394 D 512562 CDS YP_001910909.1 188528222 6296737 1440184..1441536 1 NC_010698.2 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1441536 trmE 6296737 trmE Helicobacter pylori Shi470 tRNA modification GTPase TrmE YP_001910909.1 1440184 D 512562 CDS YP_001910910.1 188528223 6296736 1441740..1443962 1 NC_010698.2 putative Outer membrane protein 1443962 6296736 HPSH_07435 Helicobacter pylori Shi470 putative Outer membrane protein YP_001910910.1 1441740 D 512562 CDS YP_001910911.1 188528224 6296735 complement(1443959..1444102) 1 NC_010698.2 hypothetical protein 1444102 6296735 HPSH_07440 Helicobacter pylori Shi470 hypothetical protein YP_001910911.1 1443959 R 512562 CDS YP_001910912.1 188528225 6296734 complement(1444482..1445393) 1 NC_010698.2 hypothetical protein 1445393 6296734 HPSH_07445 Helicobacter pylori Shi470 hypothetical protein YP_001910912.1 1444482 R 512562 CDS YP_001910913.1 188528226 6296731 complement(1445403..1445744) 1 NC_010698.2 COG0481 Membrane GTPase LepA; hypothetical protein 1445744 6296731 HPSH_07450 Helicobacter pylori Shi470 hypothetical protein YP_001910913.1 1445403 R 512562 CDS YP_001910914.1 188528227 6296730 complement(1445752..1446279) 1 NC_010698.2 membrane-associated lipoprotein 1446279 6296730 HPSH_07455 Helicobacter pylori Shi470 membrane-associated lipoprotein YP_001910914.1 1445752 R 512562 CDS YP_001910915.1 188528228 6296729 complement(1446303..1446935) 1 NC_010698.2 hypothetical protein 1446935 6296729 HPSH_07460 Helicobacter pylori Shi470 hypothetical protein YP_001910915.1 1446303 R 512562 CDS YP_001910916.1 188528229 6296727 complement(1447292..1447606) 1 NC_010698.2 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 1447606 6296727 HPSH_07465 Helicobacter pylori Shi470 thioredoxin YP_001910916.1 1447292 R 512562 CDS YP_001910917.1 188528230 6296725 complement(1447661..1448434) 1 NC_010698.2 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; hypothetical protein 1448434 6296725 HPSH_07470 Helicobacter pylori Shi470 hypothetical protein YP_001910917.1 1447661 R 512562 CDS YP_001910918.1 188528231 6296724 complement(1448431..1452066) 1 NC_010698.2 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1452066 dnaE 6296724 dnaE Helicobacter pylori Shi470 DNA polymerase III subunit alpha YP_001910918.1 1448431 R 512562 CDS YP_001910919.1 188528232 6296723 1452214..1453266 1 NC_010698.2 COG1858 Cytochrome c peroxidase; cytochrome c551 peroxidase 1453266 6296723 HPSH_07480 Helicobacter pylori Shi470 cytochrome c551 peroxidase YP_001910919.1 1452214 D 512562 CDS YP_001910920.1 188528233 6296721 complement(1453269..1453358) 1 NC_010698.2 hypothetical protein 1453358 6296721 HPSH_07485 Helicobacter pylori Shi470 hypothetical protein YP_001910920.1 1453269 R 512562 CDS YP_001910921.1 188528234 6296720 complement(1453443..1454030) 1 NC_010698.2 COG3187 Heat shock protein; putative secreted motility protein 1454030 6296720 HPSH_07490 Helicobacter pylori Shi470 putative secreted motility protein YP_001910921.1 1453443 R 512562 CDS YP_001910922.1 188528235 6296719 complement(1454049..1454726) 1 NC_010698.2 hypothetical protein 1454726 6296719 HPSH_07495 Helicobacter pylori Shi470 hypothetical protein YP_001910922.1 1454049 R 512562 CDS YP_001910923.1 188528236 6296718 complement(1454729..1455544) 1 NC_010698.2 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; ABC transport system substrate binding protein 1455544 6296718 HPSH_07500 Helicobacter pylori Shi470 ABC transport system substrate binding protein YP_001910923.1 1454729 R 512562 CDS YP_001910924.1 188528237 6296717 complement(1455529..1456317) 1 NC_010698.2 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; ABC transporter ATP-binding protein 1456317 6296717 HPSH_07505 Helicobacter pylori Shi470 ABC transporter ATP-binding protein YP_001910924.1 1455529 R 512562 CDS YP_001910925.1 188528238 6296716 complement(1456314..1457447) 1 NC_010698.2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; hypothetical protein 1457447 6296716 HPSH_07510 Helicobacter pylori Shi470 hypothetical protein YP_001910925.1 1456314 R 512562 CDS YP_001910926.1 188528239 6296783 1457581..1458276 1 NC_010698.2 outer membrane protein 1458276 6296783 HPSH_07515 Helicobacter pylori Shi470 outer membrane protein YP_001910926.1 1457581 D 512562 CDS YP_001910927.1 188528240 6296712 complement(1458281..1459303) 1 NC_010698.2 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1459303 6296712 HPSH_07520 Helicobacter pylori Shi470 branched-chain amino acid aminotransferase YP_001910927.1 1458281 R 512562 CDS YP_001910928.1 188528241 6296710 complement(1459354..1460100) 1 NC_010698.2 outer membrane protein 1460100 6296710 HPSH_07525 Helicobacter pylori Shi470 outer membrane protein YP_001910928.1 1459354 R 512562 CDS YP_001910929.1 188528242 6296709 complement(1460215..1462896) 1 NC_010698.2 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); DNA polymerase I PolA 1462896 6296709 HPSH_07530 Helicobacter pylori Shi470 DNA polymerase I PolA YP_001910929.1 1460215 R 512562 CDS YP_002154434.1 209406225 6972671 complement(1463549..1466224) 1 NC_010698.2 type II restriction modification enzyme methyltransferase 1466224 6972671 HPSH_07540 Helicobacter pylori Shi470 type II restriction modification enzyme methyltransferase YP_002154434.1 1463549 R 512562 CDS YP_001910930.1 188528243 6296708 complement(1466257..1466832) 1 NC_010698.2 hypothetical protein 1466832 6296708 HPSH_07545 Helicobacter pylori Shi470 hypothetical protein YP_001910930.1 1466257 R 512562 CDS YP_001910931.1 188528244 6296707 complement(1466820..1467395) 1 NC_010698.2 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1467395 tmk 6296707 tmk Helicobacter pylori Shi470 thymidylate kinase YP_001910931.1 1466820 R 512562 CDS YP_001910932.1 188528245 6296706 complement(1467397..1467870) 1 NC_010698.2 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1467870 coaD 6296706 coaD Helicobacter pylori Shi470 phosphopantetheine adenylyltransferase YP_001910932.1 1467397 R 512562 CDS YP_001910933.1 188528246 6296705 complement(1467870..1468433) 1 NC_010698.2 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1468433 6296705 HPSH_07560 Helicobacter pylori Shi470 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001910933.1 1467870 R 512562 CDS YP_001910934.1 188528247 6296704 1468414..1468518 1 NC_010698.2 hypothetical protein 1468518 6296704 HPSH_07565 Helicobacter pylori Shi470 hypothetical protein YP_001910934.1 1468414 D 512562 CDS YP_001910935.1 188528248 6296702 complement(1468443..1469099) 1 NC_010698.2 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1469099 flgA 6296702 flgA Helicobacter pylori Shi470 flagellar basal body P-ring biosynthesis protein FlgA YP_001910935.1 1468443 R 512562 CDS YP_001910936.1 188528249 6296701 complement(1469096..1471141) 1 NC_010698.2 COG0210 Superfamily I DNA and RNA helicases; DNA helicase II 1471141 6296701 HPSH_07575 Helicobacter pylori Shi470 DNA helicase II YP_001910936.1 1469096 R 512562 CDS YP_001910937.1 188528250 6296700 complement(1471141..1473675) 1 NC_010698.2 COG0457 FOG: TPR repeat; hypothetical protein 1473675 6296700 HPSH_07580 Helicobacter pylori Shi470 hypothetical protein YP_001910937.1 1471141 R 512562 CDS YP_001910938.1 188528251 6296699 complement(1473685..1474932) 1 NC_010698.2 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1474932 6296699 HPSH_07585 Helicobacter pylori Shi470 seryl-tRNA synthetase YP_001910938.1 1473685 R 512562 CDS YP_001910939.1 188528252 6296698 complement(1474933..1475730) 1 NC_010698.2 COG0388 Predicted amidohydrolase; hypothetical protein 1475730 6296698 HPSH_07590 Helicobacter pylori Shi470 hypothetical protein YP_001910939.1 1474933 R 512562 CDS YP_001910940.1 188528253 6296697 complement(1475734..1475994) 1 NC_010698.2 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1475994 6296697 HPSH_07595 Helicobacter pylori Shi470 exodeoxyribonuclease VII small subunit YP_001910940.1 1475734 R 512562 CDS YP_001910941.1 188528254 6296696 complement(1476004..1476744) 1 NC_010698.2 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1476744 ubiE 6296696 ubiE Helicobacter pylori Shi470 ubiquinone/menaquinone biosynthesis methyltransferase YP_001910941.1 1476004 R 512562 CDS YP_001910942.1 188528255 6296675 complement(1476754..1477200) 1 NC_010698.2 COG1981 Predicted membrane protein; hypothetical protein 1477200 6296675 HPSH_07605 Helicobacter pylori Shi470 hypothetical protein YP_001910942.1 1476754 R 512562 CDS YP_001910943.1 188528256 6296889 complement(1477211..1477783) 1 NC_010698.2 COG1739 Uncharacterized conserved protein; hypothetical protein 1477783 6296889 HPSH_07610 Helicobacter pylori Shi470 hypothetical protein YP_001910943.1 1477211 R 512562 CDS YP_001910944.1 188528257 6296842 complement(1477770..1478900) 1 NC_010698.2 COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 1478900 6296842 HPSH_07615 Helicobacter pylori Shi470 hypothetical protein YP_001910944.1 1477770 R 512562 CDS YP_001910945.1 188528258 6296694 complement(1478897..1479985) 1 NC_010698.2 COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 1479985 6296694 HPSH_07620 Helicobacter pylori Shi470 hypothetical protein YP_001910945.1 1478897 R 512562 CDS YP_001910946.1 188528259 6296693 complement(1480006..1480995) 1 NC_010698.2 COG0845 Membrane-fusion protein; hypothetical protein 1480995 6296693 HPSH_07625 Helicobacter pylori Shi470 hypothetical protein YP_001910946.1 1480006 R 512562 CDS YP_001910947.1 188528260 6296692 complement(1481007..1482539) 1 NC_010698.2 COG1538 Outer membrane protein; lipase-like protein 1482539 6296692 HPSH_07630 Helicobacter pylori Shi470 lipase-like protein YP_001910947.1 1481007 R 512562 CDS YP_001910948.1 188528261 6296691 complement(1482536..1483885) 1 NC_010698.2 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 1483885 6296691 HPSH_07635 Helicobacter pylori Shi470 hypothetical protein YP_001910948.1 1482536 R 512562 CDS YP_001910949.1 188528262 6296690 complement(1483984..1485585) 1 NC_010698.2 COG0306 Phosphate/sulphate permeases; phosphate permease 1485585 6296690 HPSH_07640 Helicobacter pylori Shi470 phosphate permease YP_001910949.1 1483984 R 512562 CDS YP_001910950.1 188528263 6296689 1485725..1485994 1 NC_010698.2 COG0694 Thioredoxin-like proteins and domains; hypothetical protein 1485994 6296689 HPSH_07645 Helicobacter pylori Shi470 hypothetical protein YP_001910950.1 1485725 D 512562 CDS YP_001910951.1 188528264 6296688 1486007..1486618 1 NC_010698.2 hypothetical protein 1486618 6296688 HPSH_07650 Helicobacter pylori Shi470 hypothetical protein YP_001910951.1 1486007 D 512562 CDS YP_001910952.1 188528265 6296687 1486622..1487965 1 NC_010698.2 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1487965 murE 6296687 murE Helicobacter pylori Shi470 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001910952.1 1486622 D 512562 CDS YP_001910953.1 188528266 6296686 1487969..1488919 1 NC_010698.2 Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1488919 6296686 HPSH_07660 Helicobacter pylori Shi470 transaldolase YP_001910953.1 1487969 D 512562 CDS YP_001910954.1 188528267 6296685 1488974..1489510 1 NC_010698.2 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1489510 6296685 HPSH_07665 Helicobacter pylori Shi470 50S ribosomal protein L25/general stress protein Ctc YP_001910954.1 1488974 D 512562 CDS YP_001910955.1 188528268 6296683 1489520..1490080 1 NC_010698.2 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1490080 6296683 HPSH_07670 Helicobacter pylori Shi470 peptidyl-tRNA hydrolase YP_001910955.1 1489520 D 512562 CDS YP_001910956.1 188528269 6296682 1490135..1491202 1 NC_010698.2 COG0795 Predicted permeases; hypothetical protein 1491202 6296682 HPSH_07675 Helicobacter pylori Shi470 hypothetical protein YP_001910956.1 1490135 D 512562 CDS YP_001910957.1 188528270 6296681 1492300..1492473 1 NC_010698.2 COG0209 Ribonucleotide reductase, alpha subunit; restriction endonuclease 1492473 6296681 HPSH_07690 Helicobacter pylori Shi470 restriction endonuclease YP_001910957.1 1492300 D 512562 CDS YP_001910958.1 188528271 6296679 complement(1493654..1493761) 1 NC_010698.2 hypothetical protein 1493761 6296679 HPSH_07705 Helicobacter pylori Shi470 hypothetical protein YP_001910958.1 1493654 R 512562 CDS YP_001910959.1 188528272 6296678 1493868..1494305 1 NC_010698.2 COG3399 Uncharacterized protein conserved in bacteria; hypothetical protein 1494305 6296678 HPSH_07710 Helicobacter pylori Shi470 hypothetical protein YP_001910959.1 1493868 D 512562 CDS YP_001910960.1 188528273 6296677 complement(1494302..1496638) 1 NC_010698.2 COG2217 Cation transport ATPase; putative cation transporting P-type ATPase 1496638 6296677 HPSH_07715 Helicobacter pylori Shi470 putative cation transporting P-type ATPase YP_001910960.1 1494302 R 512562 CDS YP_001910961.1 188528274 6296676 complement(1496664..1497380) 1 NC_010698.2 COG4123 Predicted O-methyltransferase; hypothetical protein 1497380 6296676 HPSH_07720 Helicobacter pylori Shi470 hypothetical protein YP_001910961.1 1496664 R 512562 CDS YP_001910962.1 188528275 6296695 complement(1497362..1498396) 1 NC_010698.2 COG0117 Pyrimidine deaminase; riboflavin biosynthesis protein RibG 1498396 6296695 HPSH_07725 Helicobacter pylori Shi470 riboflavin biosynthesis protein RibG YP_001910962.1 1497362 R 512562 CDS YP_001910963.1 188528276 6296674 complement(1498393..1499619) 1 NC_010698.2 COG0786 Na+/glutamate symporter; sodium/glutamate symport carrier protein/glutamate permease 1499619 6296674 HPSH_07730 Helicobacter pylori Shi470 sodium/glutamate symport carrier protein/glutamate permease YP_001910963.1 1498393 R 512562 CDS YP_001910964.1 188528277 6296673 1499753..1500904 1 NC_010698.2 COG1748 Saccharopine dehydrogenase and related proteins; ATP-binding protein 1500904 6296673 HPSH_07735 Helicobacter pylori Shi470 ATP-binding protein YP_001910964.1 1499753 D 512562 CDS YP_001910965.1 188528278 6296672 complement(1500914..1502290) 1 NC_010698.2 COG0348 Polyferredoxin; ferrodoxin-like protein 1502290 6296672 HPSH_07740 Helicobacter pylori Shi470 ferrodoxin-like protein YP_001910965.1 1500914 R 512562 CDS YP_001910966.1 188528279 6296671 1502270..1503058 1 NC_010698.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 1503058 6296671 HPSH_07745 Helicobacter pylori Shi470 putative glycerol-3-phosphate acyltransferase PlsY YP_001910966.1 1502270 D 512562 CDS YP_001910967.1 188528280 6296670 1503055..1503408 1 NC_010698.2 COG1539 Dihydroneopterin aldolase; dihydroneopterin aldolase 1503408 6296670 HPSH_07750 Helicobacter pylori Shi470 dihydroneopterin aldolase YP_001910967.1 1503055 D 512562 CDS YP_001910968.1 188528281 6296669 1503392..1503718 1 NC_010698.2 FrpB-like protein 1503718 6296669 HPSH_07755 Helicobacter pylori Shi470 FrpB-like protein YP_001910968.1 1503392 D 512562 CDS YP_001910969.1 188528282 6296668 1506690..1507850 1 NC_010698.2 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1507850 6296668 HPSH_07770 Helicobacter pylori Shi470 selenocysteine synthase YP_001910969.1 1506690 D 512562 CDS YP_001910970.1 188528283 6296667 1507938..1509125 1 NC_010698.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1509125 nusA 6296667 nusA Helicobacter pylori Shi470 transcription elongation factor NusA YP_001910970.1 1507938 D 512562 CDS YP_001910971.1 188528284 6296666 1509259..1509360 1 NC_010698.2 hypothetical protein 1509360 6296666 HPSH_07780 Helicobacter pylori Shi470 hypothetical protein YP_001910971.1 1509259 D 512562 CDS YP_001910972.1 188528285 6296665 complement(1509357..1510115) 1 NC_010698.2 hypothetical protein 1510115 6296665 HPSH_07785 Helicobacter pylori Shi470 hypothetical protein YP_001910972.1 1509357 R 512562 CDS YP_001910973.1 188528286 6296664 complement(1510105..1510542) 1 NC_010698.2 COG3600 Uncharacterized phage-associated protein; phage-associated protein 1510542 6296664 HPSH_07790 Helicobacter pylori Shi470 phage-associated protein YP_001910973.1 1510105 R 512562 CDS YP_001910974.1 188528287 6296663 complement(1510751..1512370) 1 NC_010698.2 COG3344 Retron-type reverse transcriptase; hypothetical protein 1512370 6296663 HPSH_07795 Helicobacter pylori Shi470 hypothetical protein YP_001910974.1 1510751 R 512562 CDS YP_001910975.1 188528288 6296660 complement(1512387..1512911) 1 NC_010698.2 hypothetical protein 1512911 6296660 HPSH_07800 Helicobacter pylori Shi470 hypothetical protein YP_001910975.1 1512387 R 512562 CDS YP_001910976.1 188528289 6296659 complement(1512912..1516751) 1 NC_010698.2 COG1002 Type II restriction enzyme, methylase subunits; putative type II DNA modification enzyme methyltransferase 1516751 6296659 HPSH_07805 Helicobacter pylori Shi470 putative type II DNA modification enzyme methyltransferase YP_001910976.1 1512912 R 512562 CDS YP_001910977.1 188528290 6296658 complement(1516857..1519772) 1 NC_010698.2 COG3587 Restriction endonuclease; type III restriction enzyme 1519772 6296658 HPSH_07810 Helicobacter pylori Shi470 type III restriction enzyme YP_001910977.1 1516857 R 512562 CDS YP_001910978.1 188528291 6296657 complement(1519775..1521676) 1 NC_010698.2 COG2189 Adenine specific DNA methylase Mod; type III DNA modification methyltransferase 1521676 6296657 HPSH_07815 Helicobacter pylori Shi470 type III DNA modification methyltransferase YP_001910978.1 1519775 R 512562 CDS YP_001910979.1 188528292 6296542 complement(1521719..1523590) 1 NC_010698.2 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1523590 6296542 HPSH_07820 Helicobacter pylori Shi470 ATP-dependent DNA helicase RecG YP_001910979.1 1521719 R 512562 CDS YP_001910980.1 188528293 6296758 1523672..1524016 1 NC_010698.2 hypothetical protein 1524016 6296758 HPSH_07825 Helicobacter pylori Shi470 hypothetical protein YP_001910980.1 1523672 D 512562 CDS YP_001910981.1 188528294 6296742 1524020..1524655 1 NC_010698.2 hypothetical protein 1524655 6296742 HPSH_07830 Helicobacter pylori Shi470 hypothetical protein YP_001910981.1 1524020 D 512562 CDS YP_001910982.1 188528295 6296655 complement(1524652..1525404) 1 NC_010698.2 AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III 1525404 6296655 HPSH_07835 Helicobacter pylori Shi470 exodeoxyribonuclease III YP_001910982.1 1524652 R 512562 CDS YP_001910983.1 188528296 6296653 complement(1525582..1527021) 1 NC_010698.2 periplasmic competence protein 1527021 6296653 HPSH_07840 Helicobacter pylori Shi470 periplasmic competence protein YP_001910983.1 1525582 R 512562 CDS YP_001910985.1 188528298 6296648 1527148..1527222 1 NC_010698.2 hypothetical protein 1527222 6296648 HPSH_07850 Helicobacter pylori Shi470 hypothetical protein YP_001910985.1 1527148 D 512562 CDS YP_001910986.1 188528299 6296647 complement(1527250..1528617) 1 NC_010698.2 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1528617 dnaA 6296647 dnaA Helicobacter pylori Shi470 chromosomal replication initiation protein YP_001910986.1 1527250 R 512562 CDS YP_001910987.1 188528300 6296646 1528725..1529312 1 NC_010698.2 COG0813 Purine-nucleoside phosphorylase; purine nucleoside phosphorylase 1529312 6296646 HPSH_07860 Helicobacter pylori Shi470 purine nucleoside phosphorylase YP_001910987.1 1528725 D 512562 CDS YP_001910988.1 188528301 6296645 1529348..1529587 1 NC_010698.2 hypothetical protein 1529587 6296645 HPSH_07865 Helicobacter pylori Shi470 hypothetical protein YP_001910988.1 1529348 D 512562 CDS YP_001910989.1 188528302 6296644 1529588..1531381 1 NC_010698.2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1531381 6296644 HPSH_07870 Helicobacter pylori Shi470 glucosamine--fructose-6-phosphate aminotransferase YP_001910989.1 1529588 D 512562 CDS YP_001910990.1 188528303 6296643 1531402..1532028 1 NC_010698.2 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1532028 thyX 6296643 thyX Helicobacter pylori Shi470 FAD-dependent thymidylate synthase YP_001910990.1 1531402 D 512562 CDS YP_001910991.1 188528304 6296642 1532451..1532543 1 NC_010698.2 hypothetical protein 1532543 6296642 HPSH_07880 Helicobacter pylori Shi470 hypothetical protein YP_001910991.1 1532451 D 512562 CDS YP_001910992.1 188528305 6296641 complement(1532623..1533750) 1 NC_010698.2 COG0732 Restriction endonuclease S subunits; type I R-M system specificity subunit 1533750 6296641 HPSH_07885 Helicobacter pylori Shi470 type I R-M system specificity subunit YP_001910992.1 1532623 R 512562 CDS YP_001910993.1 188528306 6296640 complement(1533747..1536209) 1 NC_010698.2 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction enzyme M protein HsdM 1536209 6296640 HPSH_07890 Helicobacter pylori Shi470 type I restriction enzyme M protein HsdM YP_001910993.1 1533747 R 512562 CDS YP_001910994.1 188528307 6296638 1536280..1539255 1 NC_010698.2 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I restriction enzyme R protein HsdR 1539255 6296638 HPSH_07895 Helicobacter pylori Shi470 type I restriction enzyme R protein HsdR YP_001910994.1 1536280 D 512562 CDS YP_001910995.1 188528308 6296636 1539255..1539962 1 NC_010698.2 COG1451 Predicted metal-dependent hydrolase; hypothetical protein 1539962 6296636 HPSH_07900 Helicobacter pylori Shi470 hypothetical protein YP_001910995.1 1539255 D 512562 CDS YP_001910996.1 188528309 6296822 complement(1540052..1542577) 1 NC_010698.2 COG1629 Outer membrane receptor proteins, mostly Fe transport; iron(III dicitrate transport protein FecA 1542577 6296822 HPSH_07905 Helicobacter pylori Shi470 iron(III dicitrate transport protein FecA YP_001910996.1 1540052 R 512562 CDS YP_001910997.1 188528310 6296632 1542938..1543096 1 NC_010698.2 hypothetical protein 1543096 6296632 HPSH_07910 Helicobacter pylori Shi470 hypothetical protein YP_001910997.1 1542938 D 512562 CDS YP_001910998.1 188528311 6296631 complement(1543152..1544087) 1 NC_010698.2 COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; arginase RocF 1544087 6296631 HPSH_07915 Helicobacter pylori Shi470 arginase RocF YP_001910998.1 1543152 R 512562 CDS YP_001910999.1 188528312 6296630 1544291..1545433 1 NC_010698.2 COG0686 Alanine dehydrogenase; alanine dehydrogenase 1545433 6296630 HPSH_07920 Helicobacter pylori Shi470 alanine dehydrogenase YP_001910999.1 1544291 D 512562 CDS YP_001911000.1 188528313 6296629 1545551..1547248 1 NC_010698.2 COG1479 Uncharacterized conserved protein; hypothetical protein 1547248 6296629 HPSH_07925 Helicobacter pylori Shi470 hypothetical protein YP_001911000.1 1545551 D 512562 CDS YP_001911001.1 188528314 6296628 complement(1547259..1547987) 1 NC_010698.2 putative outer membrane protein 1547987 6296628 HPSH_07930 Helicobacter pylori Shi470 putative outer membrane protein YP_001911001.1 1547259 R 512562 CDS YP_001911002.1 188528315 6296627 1548173..1549027 1 NC_010698.2 COG0061 Predicted sugar kinase; inorganic polyphosphate/ATP-NAD kinase 1549027 6296627 HPSH_07935 Helicobacter pylori Shi470 inorganic polyphosphate/ATP-NAD kinase YP_001911002.1 1548173 D 512562 CDS YP_001911003.1 188528316 6296626 1549040..1550614 1 NC_010698.2 COG0497 ATPase involved in DNA repair; DNA repair protein 1550614 6296626 HPSH_07940 Helicobacter pylori Shi470 DNA repair protein YP_001911003.1 1549040 D 512562 CDS YP_001911004.1 188528317 6296625 1550611..1551918 1 NC_010698.2 COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; fibronectin/fibrinogen-binding protein 1551918 6296625 HPSH_07945 Helicobacter pylori Shi470 fibronectin/fibrinogen-binding protein YP_001911004.1 1550611 D 512562 CDS YP_001911005.1 188528318 6296624 1551937..1552233 1 NC_010698.2 hypothetical protein 1552233 6296624 HPSH_07950 Helicobacter pylori Shi470 hypothetical protein YP_001911005.1 1551937 D 512562 CDS YP_001911006.1 188528319 6296623 1552564..1552884 1 NC_010698.2 hypothetical protein 1552884 6296623 HPSH_07955 Helicobacter pylori Shi470 hypothetical protein YP_001911006.1 1552564 D 512562 CDS YP_001911007.1 188528320 6296622 1552923..1553252 1 NC_010698.2 hypothetical protein 1553252 6296622 HPSH_07960 Helicobacter pylori Shi470 hypothetical protein YP_001911007.1 1552923 D 512562 CDS YP_001911008.1 188528321 6296620 1553351..1553548 1 NC_010698.2 hypothetical protein 1553548 6296620 HPSH_07965 Helicobacter pylori Shi470 hypothetical protein YP_001911008.1 1553351 D 512562 CDS YP_001911009.1 188528322 6296619 complement(1553522..1554385) 1 NC_010698.2 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1554385 6296619 HPSH_07970 Helicobacter pylori Shi470 DNA polymerase III subunit epsilon YP_001911009.1 1553522 R 512562 CDS YP_001911010.1 188528323 6296618 complement(1554363..1555016) 1 NC_010698.2 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1555016 6296618 HPSH_07975 Helicobacter pylori Shi470 ribulose-phosphate 3-epimerase YP_001911010.1 1554363 R 512562 CDS YP_001911011.1 188528324 6296617 1555087..1555959 1 NC_010698.2 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1555959 6296617 HPSH_07980 Helicobacter pylori Shi470 fructose-1,6-bisphosphatase YP_001911011.1 1555087 D 512562 CDS YP_001911012.1 188528325 6296514 1555959..1556162 1 NC_010698.2 hypothetical protein 1556162 6296514 HPSH_07985 Helicobacter pylori Shi470 hypothetical protein YP_001911012.1 1555959 D 512562 CDS YP_001911013.1 188528326 6296634 1556175..1557071 1 NC_010698.2 COG0827 Adenine-specific DNA methylase; putative type II methylase protein 1557071 6296634 HPSH_07990 Helicobacter pylori Shi470 putative type II methylase protein YP_001911013.1 1556175 D 512562 CDS YP_001911014.1 188528327 6296169 1557064..1557795 1 NC_010698.2 hypothetical protein 1557795 6296169 HPSH_07995 Helicobacter pylori Shi470 hypothetical protein YP_001911014.1 1557064 D 512562 CDS YP_001911015.1 188528328 6296616 complement(1557885..1558337) 1 NC_010698.2 hypothetical protein 1558337 6296616 HPSH_08000 Helicobacter pylori Shi470 hypothetical protein YP_001911015.1 1557885 R 512562 CDS YP_001911016.1 188528329 6296612 complement(1558389..1559456) 1 NC_010698.2 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1559456 tsf 6296612 tsf Helicobacter pylori Shi470 elongation factor Ts YP_001911016.1 1558389 R 512562 CDS YP_001911017.1 188528330 6296609 complement(1559456..1560250) 1 NC_010698.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1560250 rpsB 6296609 rpsB Helicobacter pylori Shi470 30S ribosomal protein S2 YP_001911017.1 1559456 R 512562 CDS YP_001911018.1 188528331 6296608 1560343..1560429 1 NC_010698.2 hypothetical protein 1560429 6296608 HPSH_08015 Helicobacter pylori Shi470 hypothetical protein YP_001911018.1 1560343 D 512562 CDS YP_001911019.1 188528332 6296607 1560501..1563350 1 NC_010698.2 COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); putative recombination protein RecB 1563350 6296607 HPSH_08020 Helicobacter pylori Shi470 putative recombination protein RecB YP_001911019.1 1560501 D 512562 CDS YP_001911020.1 188528333 6296606 1563341..1564690 1 NC_010698.2 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1564690 nhaA 6296606 nhaA Helicobacter pylori Shi470 pH-dependent sodium/proton antiporter YP_001911020.1 1563341 D 512562 CDS YP_001911021.1 188528334 6296605 1564738..1565031 1 NC_010698.2 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1565031 yajC 6296605 yajC Helicobacter pylori Shi470 preprotein translocase subunit YajC YP_001911021.1 1564738 D 512562 CDS YP_001911022.1 188528335 6296603 1565031..1566608 1 NC_010698.2 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1566608 secD 6296603 secD Helicobacter pylori Shi470 preprotein translocase subunit SecD YP_001911022.1 1565031 D 512562 CDS YP_001911023.1 188528336 6296601 1566617..1567588 1 NC_010698.2 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1567588 secF 6296601 secF Helicobacter pylori Shi470 preprotein translocase subunit SecF YP_001911023.1 1566617 D 512562 CDS YP_001911024.1 188528337 6296600 1567598..1567936 1 NC_010698.2 hypothetical protein 1567936 6296600 HPSH_08045 Helicobacter pylori Shi470 hypothetical protein YP_001911024.1 1567598 D 512562 CDS YP_001911025.1 188528338 6296599 1567946..1570366 1 NC_010698.2 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1570366 leuS 6296599 leuS Helicobacter pylori Shi470 leucyl-tRNA synthetase YP_001911025.1 1567946 D 512562 CDS YP_001911026.1 188528339 6296598 1570363..1570875 1 NC_010698.2 hypothetical protein 1570875 6296598 HPSH_08055 Helicobacter pylori Shi470 hypothetical protein YP_001911026.1 1570363 D 512562 CDS YP_001911027.1 188528340 6296597 1570865..1572034 1 NC_010698.2 COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 1572034 6296597 HPSH_08060 Helicobacter pylori Shi470 folylpolyglutamate synthase YP_001911027.1 1570865 D 512562 CDS YP_002154435.1 209406224 6972668 1572034..1572960 1 NC_010698.2 tox-R activated gene 1572960 6972668 HPSH_08065 Helicobacter pylori Shi470 tox-R activated gene YP_002154435.1 1572034 D 512562 CDS YP_001911028.1 188528341 6296596 1572969..1573904 1 NC_010698.2 COG0739 Membrane proteins related to metalloendopeptidases; toxR-activated gene TagE 1573904 6296596 HPSH_08075 Helicobacter pylori Shi470 toxR-activated gene TagE YP_001911028.1 1572969 D 512562 CDS YP_001911029.1 188528342 6296595 1573919..1574233 1 NC_010698.2 COG1664 Integral membrane protein CcmA involved in cell shape determination; hypothetical protein 1574233 6296595 HPSH_08080 Helicobacter pylori Shi470 hypothetical protein YP_001911029.1 1573919 D 512562 CDS YP_001911030.1 188528343 6296594 1574237..1577236 1 NC_010698.2 COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 1577236 6296594 HPSH_08085 Helicobacter pylori Shi470 transcription-repair coupling factor YP_001911030.1 1574237 D 512562 CDS YP_001911031.1 188528344 6296592 1577361..1577864 1 NC_010698.2 COG0723 Rieske Fe-S protein; ubiquinol cytochrome c oxidoreductase, Rieske 2Fe-2S subunit FbcF 1577864 6296592 HPSH_08090 Helicobacter pylori Shi470 ubiquinol cytochrome c oxidoreductase, Rieske 2Fe-2S subunit FbcF YP_001911031.1 1577361 D 512562 CDS YP_001911032.1 188528345 6296591 1577875..1579113 1 NC_010698.2 COG1290 Cytochrome b subunit of the bc complex; ubiquinol cytochrome c oxidoreductase, cytochrome b subunit FbcH 1579113 6296591 HPSH_08095 Helicobacter pylori Shi470 ubiquinol cytochrome c oxidoreductase, cytochrome b subunit FbcH YP_001911032.1 1577875 D 512562 CDS YP_001911033.1 188528346 6296738 1579110..1579967 1 NC_010698.2 COG2857 Cytochrome c1; ubiquinol cytochrome c oxidoreductase, cytochrome c1 1579967 6296738 HPSH_08100 Helicobacter pylori Shi470 ubiquinol cytochrome c oxidoreductase, cytochrome c1 YP_001911033.1 1579110 D 512562 CDS YP_001911034.1 188528347 6296589 complement(1580172..1580507) 1 NC_010698.2 hypothetical protein 1580507 6296589 HPSH_08105 Helicobacter pylori Shi470 hypothetical protein YP_001911034.1 1580172 R 512562 CDS YP_001911035.1 188528348 6296587 complement(1580949..1582796) 1 NC_010698.2 COG0768 Cell division protein FtsI/penicillin-binding protein 2; cell division protein 1582796 6296587 HPSH_08110 Helicobacter pylori Shi470 cell division protein YP_001911035.1 1580949 R 512562 CDS YP_001911036.1 188528349 6296586 complement(1582952..1583281) 1 NC_010698.2 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1583281 fliE 6296586 fliE Helicobacter pylori Shi470 flagellar hook-basal body protein FliE YP_001911036.1 1582952 R 512562 CDS YP_001911037.1 188528350 6296584 complement(1583409..1583894) 1 NC_010698.2 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1583894 flgC 6296584 flgC Helicobacter pylori Shi470 flagellar basal body rod protein FlgC YP_001911037.1 1583409 R 512562 CDS YP_001911038.1 188528351 6296583 complement(1583907..1584329) 1 NC_010698.2 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1584329 flgB 6296583 flgB Helicobacter pylori Shi470 flagellar basal body rod protein FlgB YP_001911038.1 1583907 R 512562 CDS YP_001911039.1 188528352 6296581 1584538..1585704 1 NC_010698.2 COG0772 Bacterial cell division membrane protein; putative rod shape-determining protein 1585704 6296581 HPSH_08130 Helicobacter pylori Shi470 putative rod shape-determining protein YP_001911039.1 1584538 D 512562 CDS YP_001911040.1 188528353 6296580 complement(1585728..1586729) 1 NC_010698.2 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; hypothetical protein 1586729 6296580 HPSH_08135 Helicobacter pylori Shi470 hypothetical protein YP_001911040.1 1585728 R 512562 CDS YP_001911041.1 188528354 6296579 complement(1586928..1587935) 1 NC_010698.2 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; iron(III ABC transporter periplasmic iron-binding protein CeuE 1587935 6296579 HPSH_08140 Helicobacter pylori Shi470 iron(III ABC transporter periplasmic iron-binding protein CeuE YP_001911041.1 1586928 R 512562 CDS YP_001911042.1 188528355 6296577 1588174..1588770 1 NC_010698.2 COG0450 Peroxiredoxin; putative peroxidase 1588770 6296577 HPSH_08145 Helicobacter pylori Shi470 putative peroxidase YP_001911042.1 1588174 D 512562 CDS YP_001911043.1 188528356 6296576 1588915..1589730 1 NC_010698.2 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; outer membrane protein 1589730 6296576 HPSH_08150 Helicobacter pylori Shi470 outer membrane protein YP_001911043.1 1588915 D 512562 CDS YP_001911044.1 188528357 6296575 complement(1589798..1591573) 1 NC_010698.2 COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 2 (pbp2) 1591573 6296575 HPSH_08155 Helicobacter pylori Shi470 penicillin-binding protein 2 (pbp2) YP_001911044.1 1589798 R 512562 CDS YP_001911045.1 188528358 6296574 complement(1591554..1591997) 1 NC_010698.2 hypothetical protein 1591997 6296574 HPSH_08160 Helicobacter pylori Shi470 hypothetical protein YP_001911045.1 1591554 R 512562 CDS YP_001911046.1 188528359 6296573 complement(1592010..1592636) 1 NC_010698.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1592636 engB 6296573 engB Helicobacter pylori Shi470 ribosome biogenesis GTP-binding protein YsxC YP_001911046.1 1592010 R 512562 CDS YP_001911047.1 188528360 6296567 complement(1592633..1593190) 1 NC_010698.2 COG1934 Uncharacterized protein conserved in bacteria; hypothetical protein 1593190 6296567 HPSH_08170 Helicobacter pylori Shi470 hypothetical protein YP_001911047.1 1592633 R 512562 CDS YP_001911048.1 188528361 6296566 complement(1593190..1593783) 1 NC_010698.2 hypothetical protein 1593783 6296566 HPSH_08175 Helicobacter pylori Shi470 hypothetical protein YP_001911048.1 1593190 R 512562 CDS YP_001911049.1 188528362 6296533 complement(1593758..1594252) 1 NC_010698.2 COG1778 Low specificity phosphatase (HAD superfamily); hypothetical protein 1594252 6296533 HPSH_08180 Helicobacter pylori Shi470 hypothetical protein YP_001911049.1 1593758 R 512562 CDS YP_001911050.1 188528363 6296713 complement(1594249..1595196) 1 NC_010698.2 COG0797 Lipoproteins; rare lipoprotein A RlpA 1595196 6296713 HPSH_08185 Helicobacter pylori Shi470 rare lipoprotein A RlpA YP_001911050.1 1594249 R 512562 CDS YP_001911051.1 188528364 6296375 complement(1595196..1596308) 1 NC_010698.2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); putative regulatory protein 1596308 6296375 HPSH_08190 Helicobacter pylori Shi470 putative regulatory protein YP_001911051.1 1595196 R 512562 CDS YP_001911052.1 188528365 6296563 complement(1596409..1597173) 1 NC_010698.2 COG0084 Mg-dependent DNase; DNAse 1597173 6296563 HPSH_08195 Helicobacter pylori Shi470 DNAse YP_001911052.1 1596409 R 512562 CDS YP_001911053.1 188528366 6296562 1597248..1597868 1 NC_010698.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1597868 6296562 HPSH_08200 Helicobacter pylori Shi470 riboflavin synthase subunit alpha YP_001911053.1 1597248 D 512562 CDS YP_001911054.1 188528367 6296561 1597869..1598141 1 NC_010698.2 COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB; FlhB-related flagellar biosynthesis protein 1598141 6296561 HPSH_08205 Helicobacter pylori Shi470 FlhB-related flagellar biosynthesis protein YP_001911054.1 1597869 D 512562 CDS YP_001911055.1 188528368 6296560 1598163..1599146 1 NC_010698.2 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 1599146 metN 6296560 metN Helicobacter pylori Shi470 DL-methionine transporter ATP-binding subunit YP_001911055.1 1598163 D 512562 CDS YP_001911056.1 188528369 6296558 1599148..1599795 1 NC_010698.2 COG2011 ABC-type metal ion transport system, permease component; ABC transporter permease 1599795 6296558 HPSH_08215 Helicobacter pylori Shi470 ABC transporter permease YP_001911056.1 1599148 D 512562 CDS YP_001911057.1 188528370 6296557 complement(1599984..1600415) 1 NC_010698.2 hypothetical protein 1600415 6296557 HPSH_08220 Helicobacter pylori Shi470 hypothetical protein YP_001911057.1 1599984 R 512562 CDS YP_001911058.1 188528371 6296556 complement(1600425..1601021) 1 NC_010698.2 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 1601021 6296556 HPSH_08225 Helicobacter pylori Shi470 hypothetical protein YP_001911058.1 1600425 R 512562 CDS YP_001911059.1 188528372 6296555 complement(1601021..1602019) 1 NC_010698.2 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; undecaprenyl phosphate N-acetylglucosaminyltransferase 1602019 6296555 HPSH_08230 Helicobacter pylori Shi470 undecaprenyl phosphate N-acetylglucosaminyltransferase YP_001911059.1 1601021 R 512562 CDS YP_001911060.1 188528373 6296554 1602164..1602952 1 NC_010698.2 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1602952 6296554 HPSH_08235 Helicobacter pylori Shi470 pyridoxine 5'-phosphate synthase YP_001911060.1 1602164 D 512562 CDS YP_001911061.1 188528374 6296553 1602954..1603877 1 NC_010698.2 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1603877 pdxA 6296553 pdxA Helicobacter pylori Shi470 4-hydroxythreonine-4-phosphate dehydrogenase YP_001911061.1 1602954 D 512562 CDS YP_001911062.1 188528375 6296552 1603941..1604963 1 NC_010698.2 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1604963 6296552 HPSH_08245 Helicobacter pylori Shi470 putative DNA-binding/iron metalloprotein/AP endonuclease YP_001911062.1 1603941 D 512562 CDS YP_001911063.1 188528376 6296550 1605142..1605930 1 NC_010698.2 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1605930 flgG 6296550 flgG Helicobacter pylori Shi470 flagellar basal body rod protein FlgG YP_001911063.1 1605142 D 512562 CDS YP_001911064.1 188528377 6296549 complement(1606736..1606873) 1 NC_010698.2 hypothetical protein 1606873 6296549 HPSH_08265 Helicobacter pylori Shi470 hypothetical protein YP_001911064.1 1606736 R 512562 CDS YP_001911065.1 188528378 6296545 complement(1607319..1607459) 1 NC_010698.2 hypothetical protein 1607459 6296545 HPSH_08270 Helicobacter pylori Shi470 hypothetical protein YP_001911065.1 1607319 R 512562 CDS YP_001911066.1 188528379 6296544 complement(1607544..1608305) 1 NC_010698.2 COG4735 Uncharacterized protein conserved in bacteria; hypothetical protein 1608305 6296544 HPSH_08275 Helicobacter pylori Shi470 hypothetical protein YP_001911066.1 1607544 R 512562 CDS