-- dump date   	20140619_113840
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1055528000001	Initiator Replication protein; Region: Rep_3; pfam01051
1055528000002	V-type ATP synthase subunit I; Validated; Region: PRK05771
1055528000003	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
1055528000004	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1055528000005	Initiator Replication protein; Region: Rep_3; pfam01051
1055528000006	Fic family protein [Function unknown]; Region: COG3177
1055528000007	Fic/DOC family; Region: Fic; pfam02661
1055528000008	Fic family protein [Function unknown]; Region: COG3177
1055528000009	Fic/DOC family; Region: Fic; pfam02661
1055528000010	Eukaryotic and archaeal DNA primase small subunit; Region: DNA_primase_S; pfam01896
1055528000011	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
1055528000012	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1055528000013	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1055528000014	putative RNA binding site [nucleotide binding]; other site
1055528000015	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1055528000016	homopentamer interface [polypeptide binding]; other site
1055528000017	active site
1055528000018	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1055528000019	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1055528000020	active site clefts [active]
1055528000021	zinc binding site [ion binding]; other site
1055528000022	dimer interface [polypeptide binding]; other site
1055528000023	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1055528000024	active site
1055528000025	dimer interface [polypeptide binding]; other site
1055528000026	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1055528000027	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1055528000028	active site
1055528000029	ATP-binding site [chemical binding]; other site
1055528000030	pantoate-binding site; other site
1055528000031	HXXH motif; other site
1055528000032	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000033	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1055528000034	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1055528000035	ring oligomerisation interface [polypeptide binding]; other site
1055528000036	ATP/Mg binding site [chemical binding]; other site
1055528000037	stacking interactions; other site
1055528000038	hinge regions; other site
1055528000039	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1055528000040	oligomerisation interface [polypeptide binding]; other site
1055528000041	mobile loop; other site
1055528000042	roof hairpin; other site
1055528000043	DNA primase, catalytic core; Region: dnaG; TIGR01391
1055528000044	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1055528000045	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1055528000046	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1055528000047	active site
1055528000048	metal binding site [ion binding]; metal-binding site
1055528000049	interdomain interaction site; other site
1055528000050	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1055528000051	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1055528000052	Ligand Binding Site [chemical binding]; other site
1055528000053	TrbC/VIRB2 family; Region: TrbC; cl01583
1055528000054	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1055528000055	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1055528000056	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1055528000057	Walker A motif; other site
1055528000058	ATP binding site [chemical binding]; other site
1055528000059	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1055528000060	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
1055528000061	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
1055528000062	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055528000063	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528000064	active site
1055528000065	phosphorylation site [posttranslational modification]
1055528000066	intermolecular recognition site; other site
1055528000067	dimerization interface [polypeptide binding]; other site
1055528000068	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
1055528000069	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
1055528000070	dimer interface [polypeptide binding]; other site
1055528000071	active site
1055528000072	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055528000073	catalytic residues [active]
1055528000074	substrate binding site [chemical binding]; other site
1055528000075	lipid A 1-phosphatase; Reviewed; Region: PRK09597
1055528000076	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1055528000077	active site
1055528000078	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
1055528000079	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1055528000080	Sulfatase; Region: Sulfatase; pfam00884
1055528000081	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000082	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1055528000083	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1055528000084	dimer interface [polypeptide binding]; other site
1055528000085	active site
1055528000086	citrylCoA binding site [chemical binding]; other site
1055528000087	NADH binding [chemical binding]; other site
1055528000088	cationic pore residues; other site
1055528000089	oxalacetate/citrate binding site [chemical binding]; other site
1055528000090	coenzyme A binding site [chemical binding]; other site
1055528000091	catalytic triad [active]
1055528000092	isocitrate dehydrogenase; Validated; Region: PRK07362
1055528000093	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1055528000094	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
1055528000095	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1055528000096	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1055528000097	Ligand Binding Site [chemical binding]; other site
1055528000098	Uncharacterized conserved protein [Function unknown]; Region: COG2127
1055528000099	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1055528000100	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528000101	Walker A motif; other site
1055528000102	ATP binding site [chemical binding]; other site
1055528000103	Walker B motif; other site
1055528000104	arginine finger; other site
1055528000105	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528000106	Walker A motif; other site
1055528000107	ATP binding site [chemical binding]; other site
1055528000108	Walker B motif; other site
1055528000109	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1055528000110	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1055528000111	tetramerization interface [polypeptide binding]; other site
1055528000112	active site
1055528000113	hypothetical protein; Provisional; Region: PRK03762
1055528000114	PDZ domain; Region: PDZ_2; pfam13180
1055528000115	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1055528000116	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
1055528000117	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1055528000118	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
1055528000119	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1055528000120	VirB7 interaction site; other site
1055528000121	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1055528000122	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1055528000123	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1055528000124	Substrate binding site; other site
1055528000125	Cupin domain; Region: Cupin_2; cl17218
1055528000126	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
1055528000127	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1055528000128	NADP-binding site; other site
1055528000129	homotetramer interface [polypeptide binding]; other site
1055528000130	substrate binding site [chemical binding]; other site
1055528000131	homodimer interface [polypeptide binding]; other site
1055528000132	active site
1055528000133	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1055528000134	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1055528000135	NADP binding site [chemical binding]; other site
1055528000136	active site
1055528000137	putative substrate binding site [chemical binding]; other site
1055528000138	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1055528000139	dimerization interface [polypeptide binding]; other site
1055528000140	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1055528000141	ATP binding site [chemical binding]; other site
1055528000142	Acylphosphatase; Region: Acylphosphatase; pfam00708
1055528000143	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
1055528000144	HypF finger; Region: zf-HYPF; pfam07503
1055528000145	HypF finger; Region: zf-HYPF; pfam07503
1055528000146	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1055528000147	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
1055528000148	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1055528000149	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528000150	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528000151	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1055528000152	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055528000153	cofactor binding site; other site
1055528000154	DNA binding site [nucleotide binding]
1055528000155	substrate interaction site [chemical binding]; other site
1055528000156	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055528000157	potential frameshift: common BLAST hit: gi|210134247|ref|YP_002300686.1| restriction endonuclease
1055528000158	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1055528000159	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1055528000160	Na binding site [ion binding]; other site
1055528000161	Proline dehydrogenase; Region: Pro_dh; pfam01619
1055528000162	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1055528000163	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1055528000164	Glutamate binding site [chemical binding]; other site
1055528000165	NAD binding site [chemical binding]; other site
1055528000166	catalytic residues [active]
1055528000167	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
1055528000168	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
1055528000169	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1055528000170	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1055528000171	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1055528000172	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
1055528000173	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1055528000174	G1 box; other site
1055528000175	GTP/Mg2+ binding site [chemical binding]; other site
1055528000176	G2 box; other site
1055528000177	Switch I region; other site
1055528000178	G3 box; other site
1055528000179	Switch II region; other site
1055528000180	G4 box; other site
1055528000181	G5 box; other site
1055528000182	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
1055528000183	UreF; Region: UreF; pfam01730
1055528000184	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
1055528000185	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
1055528000186	dimer interface [polypeptide binding]; other site
1055528000187	catalytic residues [active]
1055528000188	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
1055528000189	urease subunit beta; Provisional; Region: ureB; PRK13985
1055528000190	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1055528000191	subunit interactions [polypeptide binding]; other site
1055528000192	active site
1055528000193	flap region; other site
1055528000194	urease subunit alpha; Provisional; Region: PRK13986
1055528000195	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1055528000196	alpha-gamma subunit interface [polypeptide binding]; other site
1055528000197	beta-gamma subunit interface [polypeptide binding]; other site
1055528000198	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1055528000199	gamma-beta subunit interface [polypeptide binding]; other site
1055528000200	alpha-beta subunit interface [polypeptide binding]; other site
1055528000201	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1055528000202	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
1055528000203	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1055528000204	active site
1055528000205	substrate binding site [chemical binding]; other site
1055528000206	metal binding site [ion binding]; metal-binding site
1055528000207	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1055528000208	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1055528000209	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1055528000210	RF-1 domain; Region: RF-1; pfam00472
1055528000211	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000212	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055528000213	dimer interface [polypeptide binding]; other site
1055528000214	putative CheW interface [polypeptide binding]; other site
1055528000215	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1055528000216	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1055528000217	23S rRNA interface [nucleotide binding]; other site
1055528000218	L3 interface [polypeptide binding]; other site
1055528000219	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
1055528000220	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1055528000221	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
1055528000222	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1055528000223	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1055528000224	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1055528000225	NlpC/P60 family; Region: NLPC_P60; pfam00877
1055528000226	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1055528000227	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1055528000228	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1055528000229	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1055528000230	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1055528000231	DNA binding residues [nucleotide binding]
1055528000232	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1055528000233	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1055528000234	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1055528000235	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1055528000236	potential protein location (hypothetical protein HPPN120_00460 [Helicobacter pylori Puno120]) that overlaps RNA (tRNA-S)
1055528000237	Protein of unknown function (DUF511); Region: DUF511; pfam04373
1055528000238	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528000239	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055528000240	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528000241	potential frameshift: common BLAST hit: gi|298736963|ref|YP_003729493.1| putative alpha(1,2)fucosyltransferase
1055528000242	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
1055528000243	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1055528000244	putative ligand binding site [chemical binding]; other site
1055528000245	putative NAD binding site [chemical binding]; other site
1055528000246	catalytic site [active]
1055528000247	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1055528000248	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1055528000249	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528000250	catalytic residue [active]
1055528000251	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1055528000252	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055528000253	dimer interface [polypeptide binding]; other site
1055528000254	putative CheW interface [polypeptide binding]; other site
1055528000255	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
1055528000256	Ligand Binding Site [chemical binding]; other site
1055528000257	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000258	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1055528000259	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1055528000260	metal-binding site
1055528000261	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1055528000262	active site
1055528000263	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528000264	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528000265	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1055528000266	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
1055528000267	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1055528000268	dimerization interface [polypeptide binding]; other site
1055528000269	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1055528000270	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055528000271	dimer interface [polypeptide binding]; other site
1055528000272	putative CheW interface [polypeptide binding]; other site
1055528000273	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1055528000274	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1055528000275	active site
1055528000276	metal binding site [ion binding]; metal-binding site
1055528000277	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1055528000278	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1055528000279	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
1055528000280	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1055528000281	homodimer interface [polypeptide binding]; other site
1055528000282	substrate-cofactor binding pocket; other site
1055528000283	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528000284	catalytic residue [active]
1055528000285	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1055528000286	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1055528000287	dimer interface [polypeptide binding]; other site
1055528000288	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528000289	catalytic residue [active]
1055528000290	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1055528000291	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1055528000292	nucleotide binding site [chemical binding]; other site
1055528000293	NEF interaction site [polypeptide binding]; other site
1055528000294	SBD interface [polypeptide binding]; other site
1055528000295	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1055528000296	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1055528000297	dimer interface [polypeptide binding]; other site
1055528000298	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1055528000299	heat-inducible transcription repressor; Provisional; Region: PRK03911
1055528000300	hypothetical protein; Provisional; Region: PRK05834
1055528000301	intersubunit interface [polypeptide binding]; other site
1055528000302	active site
1055528000303	Zn2+ binding site [ion binding]; other site
1055528000304	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1055528000305	flagellin B; Provisional; Region: PRK13588
1055528000306	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1055528000307	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055528000308	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055528000309	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1055528000310	DNA topoisomerase I; Validated; Region: PRK05582
1055528000311	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1055528000312	active site
1055528000313	interdomain interaction site; other site
1055528000314	putative metal-binding site [ion binding]; other site
1055528000315	nucleotide binding site [chemical binding]; other site
1055528000316	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1055528000317	domain I; other site
1055528000318	DNA binding groove [nucleotide binding]
1055528000319	phosphate binding site [ion binding]; other site
1055528000320	domain II; other site
1055528000321	domain III; other site
1055528000322	nucleotide binding site [chemical binding]; other site
1055528000323	catalytic site [active]
1055528000324	domain IV; other site
1055528000325	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1055528000326	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1055528000327	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1055528000328	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
1055528000329	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528000330	FeS/SAM binding site; other site
1055528000331	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
1055528000332	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
1055528000333	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1055528000334	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1055528000335	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1055528000336	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1055528000337	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
1055528000338	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1055528000339	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1055528000340	active site
1055528000341	dimer interface [polypeptide binding]; other site
1055528000342	motif 1; other site
1055528000343	motif 2; other site
1055528000344	motif 3; other site
1055528000345	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1055528000346	anticodon binding site; other site
1055528000347	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1055528000348	translation initiation factor IF-3; Region: infC; TIGR00168
1055528000349	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1055528000350	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1055528000351	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1055528000352	23S rRNA binding site [nucleotide binding]; other site
1055528000353	L21 binding site [polypeptide binding]; other site
1055528000354	L13 binding site [polypeptide binding]; other site
1055528000355	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000356	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1055528000357	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1055528000358	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1055528000359	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1055528000360	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1055528000361	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1055528000362	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG3200
1055528000363	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1055528000364	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1055528000365	catalytic triad [active]
1055528000366	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1055528000367	iron-sulfur cluster-binding protein; Region: TIGR00273
1055528000368	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1055528000369	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1055528000370	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1055528000371	Cysteine-rich domain; Region: CCG; pfam02754
1055528000372	Cysteine-rich domain; Region: CCG; pfam02754
1055528000373	L-lactate transport; Region: lctP; TIGR00795
1055528000374	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1055528000375	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1055528000376	L-lactate permease; Region: Lactate_perm; pfam02652
1055528000377	DNA glycosylase MutY; Provisional; Region: PRK13910
1055528000378	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1055528000379	minor groove reading motif; other site
1055528000380	helix-hairpin-helix signature motif; other site
1055528000381	substrate binding pocket [chemical binding]; other site
1055528000382	active site
1055528000383	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1055528000384	DNA binding and oxoG recognition site [nucleotide binding]
1055528000385	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1055528000386	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1055528000387	transmembrane helices; other site
1055528000388	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
1055528000389	Low-spin heme binding site [chemical binding]; other site
1055528000390	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
1055528000391	D-pathway; other site
1055528000392	Putative water exit pathway; other site
1055528000393	Binuclear center (active site) [active]
1055528000394	K-pathway; other site
1055528000395	Putative proton exit pathway; other site
1055528000396	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
1055528000397	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
1055528000398	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
1055528000399	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
1055528000400	Cytochrome c; Region: Cytochrom_C; pfam00034
1055528000401	Cytochrome c; Region: Cytochrom_C; pfam00034
1055528000402	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
1055528000403	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
1055528000404	recombinase A; Provisional; Region: recA; PRK09354
1055528000405	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1055528000406	hexamer interface [polypeptide binding]; other site
1055528000407	Walker A motif; other site
1055528000408	ATP binding site [chemical binding]; other site
1055528000409	Walker B motif; other site
1055528000410	enolase; Provisional; Region: eno; PRK00077
1055528000411	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1055528000412	dimer interface [polypeptide binding]; other site
1055528000413	metal binding site [ion binding]; metal-binding site
1055528000414	substrate binding pocket [chemical binding]; other site
1055528000415	AMIN domain; Region: AMIN; pfam11741
1055528000416	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1055528000417	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1055528000418	ADP binding site [chemical binding]; other site
1055528000419	magnesium binding site [ion binding]; other site
1055528000420	putative shikimate binding site; other site
1055528000421	Cache domain; Region: Cache_1; pfam02743
1055528000422	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055528000423	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1055528000424	Ligand binding site; other site
1055528000425	metal-binding site
1055528000426	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528000427	Sel1-like repeats; Region: SEL1; smart00671
1055528000428	Sel1-like repeats; Region: SEL1; smart00671
1055528000429	Sel1-like repeats; Region: SEL1; smart00671
1055528000430	Sel1-like repeats; Region: SEL1; smart00671
1055528000431	Sel1-like repeats; Region: SEL1; smart00671
1055528000432	Sel1-like repeats; Region: SEL1; smart00671
1055528000433	hypothetical protein; Provisional; Region: PRK12378
1055528000434	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1055528000435	dimer interface [polypeptide binding]; other site
1055528000436	active site
1055528000437	Schiff base residues; other site
1055528000438	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1055528000439	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1055528000440	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1055528000441	dimer interface [polypeptide binding]; other site
1055528000442	phosphorylation site [posttranslational modification]
1055528000443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055528000444	ATP binding site [chemical binding]; other site
1055528000445	Mg2+ binding site [ion binding]; other site
1055528000446	G-X-G motif; other site
1055528000447	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1055528000448	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528000449	active site
1055528000450	phosphorylation site [posttranslational modification]
1055528000451	intermolecular recognition site; other site
1055528000452	dimerization interface [polypeptide binding]; other site
1055528000453	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1055528000454	DNA binding site [nucleotide binding]
1055528000455	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1055528000456	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1055528000457	Peptidase family U32; Region: Peptidase_U32; pfam01136
1055528000458	peptide chain release factor 2; Region: prfB; TIGR00020
1055528000459	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1055528000460	RF-1 domain; Region: RF-1; pfam00472
1055528000461	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1055528000462	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1055528000463	dimer interface [polypeptide binding]; other site
1055528000464	putative functional site; other site
1055528000465	putative MPT binding site; other site
1055528000466	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
1055528000467	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
1055528000468	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1055528000469	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1055528000470	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1055528000471	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1055528000472	intersubunit interface [polypeptide binding]; other site
1055528000473	active site
1055528000474	zinc binding site [ion binding]; other site
1055528000475	Na+ binding site [ion binding]; other site
1055528000476	elongation factor P; Validated; Region: PRK00529
1055528000477	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1055528000478	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1055528000479	RNA binding site [nucleotide binding]; other site
1055528000480	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1055528000481	RNA binding site [nucleotide binding]; other site
1055528000482	pseudaminic acid synthase; Region: PseI; TIGR03586
1055528000483	NeuB family; Region: NeuB; pfam03102
1055528000484	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1055528000485	NeuB binding interface [polypeptide binding]; other site
1055528000486	putative substrate binding site [chemical binding]; other site
1055528000487	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1055528000488	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1055528000489	Walker A/P-loop; other site
1055528000490	ATP binding site [chemical binding]; other site
1055528000491	Q-loop/lid; other site
1055528000492	ABC transporter signature motif; other site
1055528000493	Walker B; other site
1055528000494	D-loop; other site
1055528000495	H-loop/switch region; other site
1055528000496	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
1055528000497	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1055528000498	active site
1055528000499	catalytic triad [active]
1055528000500	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1055528000501	Colicin V production protein; Region: Colicin_V; pfam02674
1055528000502	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1055528000503	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1055528000504	dimer interface [polypeptide binding]; other site
1055528000505	putative anticodon binding site; other site
1055528000506	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1055528000507	motif 1; other site
1055528000508	active site
1055528000509	motif 2; other site
1055528000510	motif 3; other site
1055528000511	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
1055528000512	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1055528000513	dimer interface [polypeptide binding]; other site
1055528000514	active site
1055528000515	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1055528000516	folate binding site [chemical binding]; other site
1055528000517	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
1055528000518	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
1055528000519	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
1055528000520	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1055528000521	putative active site [active]
1055528000522	catalytic site [active]
1055528000523	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1055528000524	PLD-like domain; Region: PLDc_2; pfam13091
1055528000525	putative active site [active]
1055528000526	catalytic site [active]
1055528000527	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
1055528000528	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1055528000529	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1055528000530	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
1055528000531	L-aspartate oxidase; Provisional; Region: PRK06175
1055528000532	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1055528000533	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
1055528000534	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
1055528000535	Iron-sulfur protein interface; other site
1055528000536	proximal heme binding site [chemical binding]; other site
1055528000537	distal heme binding site [chemical binding]; other site
1055528000538	dimer interface [polypeptide binding]; other site
1055528000539	triosephosphate isomerase; Provisional; Region: PRK14567
1055528000540	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1055528000541	substrate binding site [chemical binding]; other site
1055528000542	dimer interface [polypeptide binding]; other site
1055528000543	catalytic triad [active]
1055528000544	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
1055528000545	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1055528000546	NAD binding site [chemical binding]; other site
1055528000547	homotetramer interface [polypeptide binding]; other site
1055528000548	homodimer interface [polypeptide binding]; other site
1055528000549	substrate binding site [chemical binding]; other site
1055528000550	active site
1055528000551	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
1055528000552	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1055528000553	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1055528000554	trimer interface [polypeptide binding]; other site
1055528000555	active site
1055528000556	UDP-GlcNAc binding site [chemical binding]; other site
1055528000557	lipid binding site [chemical binding]; lipid-binding site
1055528000558	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1055528000559	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1055528000560	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1055528000561	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1055528000562	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1055528000563	active site
1055528000564	multimer interface [polypeptide binding]; other site
1055528000565	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
1055528000566	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
1055528000567	fatty acid/phospholipid synthesis protein PlsX; Region: plsX; TIGR00182
1055528000568	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
1055528000569	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1055528000570	dimer interface [polypeptide binding]; other site
1055528000571	active site
1055528000572	CoA binding pocket [chemical binding]; other site
1055528000573	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528000574	Walker A/P-loop; other site
1055528000575	ATP binding site [chemical binding]; other site
1055528000576	AAA domain; Region: AAA_21; pfam13304
1055528000577	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1055528000578	Walker B; other site
1055528000579	D-loop; other site
1055528000580	H-loop/switch region; other site
1055528000581	antiporter inner membrane protein; Provisional; Region: PRK11670
1055528000582	Domain of unknown function DUF59; Region: DUF59; pfam01883
1055528000583	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1055528000584	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055528000585	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055528000586	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055528000587	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055528000588	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528000589	heat shock protein 90; Provisional; Region: PRK05218
1055528000590	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055528000591	ATP binding site [chemical binding]; other site
1055528000592	Mg2+ binding site [ion binding]; other site
1055528000593	G-X-G motif; other site
1055528000594	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528000595	Sel1-like repeats; Region: SEL1; smart00671
1055528000596	Sel1-like repeats; Region: SEL1; smart00671
1055528000597	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055528000598	TPR motif; other site
1055528000599	binding surface
1055528000600	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1055528000601	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1055528000602	metal binding site [ion binding]; metal-binding site
1055528000603	dimer interface [polypeptide binding]; other site
1055528000604	glucose-inhibited division protein A; Region: gidA; TIGR00136
1055528000605	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1055528000606	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1055528000607	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1055528000608	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1055528000609	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1055528000610	transmembrane helices; other site
1055528000611	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1055528000612	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1055528000613	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
1055528000614	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1055528000615	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1055528000616	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1055528000617	potential frameshift: common BLAST hit: gi|210134418|ref|YP_002300857.1| beta-1,4-N-acetylgalactosamyltransferase
1055528000618	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1055528000619	substrate binding site [chemical binding]; other site
1055528000620	Helix-turn-helix domain; Region: HTH_28; pfam13518
1055528000621	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
1055528000622	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1055528000623	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055528000624	catalytic residue [active]
1055528000625	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
1055528000626	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1055528000627	trimerization site [polypeptide binding]; other site
1055528000628	active site
1055528000629	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1055528000630	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1055528000631	DNA repair protein RadA; Region: sms; TIGR00416
1055528000632	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1055528000633	Walker A motif/ATP binding site; other site
1055528000634	ATP binding site [chemical binding]; other site
1055528000635	Walker B motif; other site
1055528000636	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1055528000637	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
1055528000638	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
1055528000639	SelR domain; Region: SelR; pfam01641
1055528000640	Predicted permeases [General function prediction only]; Region: COG0730
1055528000641	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000642	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1055528000643	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1055528000644	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1055528000645	potential protein location (hypothetical protein HPPN120_01165 [Helicobacter pylori Puno120]) that overlaps RNA (tRNA-N)
1055528000646	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000647	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1055528000648	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1055528000649	Ligand binding site; other site
1055528000650	oligomer interface; other site
1055528000651	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1055528000652	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1055528000653	hypothetical protein; Provisional; Region: PRK04081
1055528000654	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1055528000655	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
1055528000656	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528000657	Sel1-like repeats; Region: SEL1; smart00671
1055528000658	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055528000659	binding surface
1055528000660	TPR motif; other site
1055528000661	Sel1-like repeats; Region: SEL1; smart00671
1055528000662	Sel1-like repeats; Region: SEL1; smart00671
1055528000663	Cytochrome c; Region: Cytochrom_C; cl11414
1055528000664	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
1055528000665	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1055528000666	domain interfaces; other site
1055528000667	active site
1055528000668	prolyl-tRNA synthetase, family II; Region: proS_fam_II; TIGR00409
1055528000669	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1055528000670	dimer interface [polypeptide binding]; other site
1055528000671	motif 1; other site
1055528000672	active site
1055528000673	motif 2; other site
1055528000674	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1055528000675	putative deacylase active site [active]
1055528000676	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1055528000677	active site
1055528000678	motif 3; other site
1055528000679	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1055528000680	anticodon binding site; other site
1055528000681	glutamyl-tRNA reductase; Region: hemA; TIGR01035
1055528000682	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1055528000683	tRNA; other site
1055528000684	putative tRNA binding site [nucleotide binding]; other site
1055528000685	putative NADP binding site [chemical binding]; other site
1055528000686	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1055528000687	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1055528000688	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1055528000689	substrate binding pocket [chemical binding]; other site
1055528000690	chain length determination region; other site
1055528000691	substrate-Mg2+ binding site; other site
1055528000692	catalytic residues [active]
1055528000693	aspartate-rich region 1; other site
1055528000694	active site lid residues [active]
1055528000695	aspartate-rich region 2; other site
1055528000696	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
1055528000697	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1055528000698	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1055528000699	dimerization interface [polypeptide binding]; other site
1055528000700	DPS ferroxidase diiron center [ion binding]; other site
1055528000701	ion pore; other site
1055528000702	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1055528000703	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1055528000704	dimer interface [polypeptide binding]; other site
1055528000705	phosphorylation site [posttranslational modification]
1055528000706	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055528000707	ATP binding site [chemical binding]; other site
1055528000708	Mg2+ binding site [ion binding]; other site
1055528000709	G-X-G motif; other site
1055528000710	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1055528000711	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1055528000712	helicase 45; Provisional; Region: PTZ00424
1055528000713	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1055528000714	ATP binding site [chemical binding]; other site
1055528000715	Mg++ binding site [ion binding]; other site
1055528000716	motif III; other site
1055528000717	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055528000718	nucleotide binding region [chemical binding]; other site
1055528000719	ATP-binding site [chemical binding]; other site
1055528000720	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1055528000721	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1055528000722	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
1055528000723	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1055528000724	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055528000725	Walker A/P-loop; other site
1055528000726	ATP binding site [chemical binding]; other site
1055528000727	Q-loop/lid; other site
1055528000728	ABC transporter signature motif; other site
1055528000729	Walker B; other site
1055528000730	D-loop; other site
1055528000731	H-loop/switch region; other site
1055528000732	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1055528000733	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055528000734	Walker A/P-loop; other site
1055528000735	ATP binding site [chemical binding]; other site
1055528000736	Q-loop/lid; other site
1055528000737	ABC transporter signature motif; other site
1055528000738	Walker B; other site
1055528000739	D-loop; other site
1055528000740	H-loop/switch region; other site
1055528000741	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1055528000742	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
1055528000743	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528000744	dimer interface [polypeptide binding]; other site
1055528000745	conserved gate region; other site
1055528000746	putative PBP binding loops; other site
1055528000747	ABC-ATPase subunit interface; other site
1055528000748	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000749	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000750	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1055528000751	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1055528000752	GDP-binding site [chemical binding]; other site
1055528000753	ACT binding site; other site
1055528000754	IMP binding site; other site
1055528000755	Flagellar FliJ protein; Region: FliJ; pfam02050
1055528000756	Uncharacterized conserved protein [Function unknown]; Region: COG3334
1055528000757	RIP metalloprotease RseP; Region: TIGR00054
1055528000758	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1055528000759	active site
1055528000760	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1055528000761	protein binding site [polypeptide binding]; other site
1055528000762	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1055528000763	putative substrate binding region [chemical binding]; other site
1055528000764	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1055528000765	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1055528000766	generic binding surface II; other site
1055528000767	generic binding surface I; other site
1055528000768	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528000769	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528000770	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1055528000771	Clp amino terminal domain; Region: Clp_N; pfam02861
1055528000772	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528000773	Walker A motif; other site
1055528000774	ATP binding site [chemical binding]; other site
1055528000775	Walker B motif; other site
1055528000776	arginine finger; other site
1055528000777	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528000778	Walker A motif; other site
1055528000779	ATP binding site [chemical binding]; other site
1055528000780	Walker B motif; other site
1055528000781	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1055528000782	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1055528000783	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1055528000784	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
1055528000785	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1055528000786	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1055528000787	active site
1055528000788	chlorohydrolase; Provisional; Region: PRK08418
1055528000789	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
1055528000790	active site
1055528000791	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1055528000792	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
1055528000793	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528000794	FeS/SAM binding site; other site
1055528000795	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1055528000796	putative acyl-acceptor binding pocket; other site
1055528000797	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1055528000798	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1055528000799	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1055528000800	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1055528000801	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055528000802	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055528000803	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055528000804	putative active site [active]
1055528000805	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1055528000806	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1055528000807	putative acyl-acceptor binding pocket; other site
1055528000808	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1055528000809	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1055528000810	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
1055528000811	TrkA-C domain; Region: TrkA_C; pfam02080
1055528000812	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1055528000813	active site
1055528000814	dimer interface [polypeptide binding]; other site
1055528000815	metal binding site [ion binding]; metal-binding site
1055528000816	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1055528000817	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1055528000818	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
1055528000819	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1055528000820	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528000821	FeS/SAM binding site; other site
1055528000822	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
1055528000823	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528000824	Walker A motif; other site
1055528000825	ATP binding site [chemical binding]; other site
1055528000826	Walker B motif; other site
1055528000827	arginine finger; other site
1055528000828	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
1055528000829	potential frameshift: common BLAST hit: gi|188527095|ref|YP_001909782.1| toxin-like outer membrane protein
1055528000830	potential frameshift: common BLAST hit: gi|188527095|ref|YP_001909782.1| toxin-like outer membrane protein
1055528000831	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1055528000832	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1055528000833	active site
1055528000834	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055528000835	substrate binding site [chemical binding]; other site
1055528000836	catalytic residues [active]
1055528000837	dimer interface [polypeptide binding]; other site
1055528000838	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
1055528000839	Uncharacterized conserved protein [Function unknown]; Region: COG4866
1055528000840	aminodeoxychorismate synthase; Provisional; Region: PRK07508
1055528000841	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1055528000842	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1055528000843	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1055528000844	substrate-cofactor binding pocket; other site
1055528000845	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528000846	catalytic residue [active]
1055528000847	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
1055528000848	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
1055528000849	multimer interface [polypeptide binding]; other site
1055528000850	active site
1055528000851	catalytic triad [active]
1055528000852	dimer interface [polypeptide binding]; other site
1055528000853	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
1055528000854	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1055528000855	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1055528000856	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1055528000857	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1055528000858	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1055528000859	peptide binding site [polypeptide binding]; other site
1055528000860	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1055528000861	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528000862	dimer interface [polypeptide binding]; other site
1055528000863	conserved gate region; other site
1055528000864	putative PBP binding loops; other site
1055528000865	ABC-ATPase subunit interface; other site
1055528000866	dipeptide transporter; Provisional; Region: PRK10913
1055528000867	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1055528000868	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528000869	dimer interface [polypeptide binding]; other site
1055528000870	conserved gate region; other site
1055528000871	putative PBP binding loops; other site
1055528000872	ABC-ATPase subunit interface; other site
1055528000873	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055528000874	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1055528000875	Walker A/P-loop; other site
1055528000876	ATP binding site [chemical binding]; other site
1055528000877	Q-loop/lid; other site
1055528000878	ABC transporter signature motif; other site
1055528000879	Walker B; other site
1055528000880	D-loop; other site
1055528000881	H-loop/switch region; other site
1055528000882	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1055528000883	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1055528000884	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1055528000885	Walker A/P-loop; other site
1055528000886	ATP binding site [chemical binding]; other site
1055528000887	Q-loop/lid; other site
1055528000888	ABC transporter signature motif; other site
1055528000889	Walker B; other site
1055528000890	D-loop; other site
1055528000891	H-loop/switch region; other site
1055528000892	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1055528000893	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1055528000894	GTP1/OBG; Region: GTP1_OBG; pfam01018
1055528000895	Obg GTPase; Region: Obg; cd01898
1055528000896	G1 box; other site
1055528000897	GTP/Mg2+ binding site [chemical binding]; other site
1055528000898	Switch I region; other site
1055528000899	G2 box; other site
1055528000900	G3 box; other site
1055528000901	Switch II region; other site
1055528000902	G4 box; other site
1055528000903	G5 box; other site
1055528000904	Alginate lyase; Region: Alginate_lyase; pfam05426
1055528000905	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1055528000906	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1055528000907	inhibitor-cofactor binding pocket; inhibition site
1055528000908	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528000909	catalytic residue [active]
1055528000910	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1055528000911	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1055528000912	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1055528000913	active site
1055528000914	catalytic triad [active]
1055528000915	dimer interface [polypeptide binding]; other site
1055528000916	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1055528000917	active site
1055528000918	catalytic site [active]
1055528000919	Zn binding site [ion binding]; other site
1055528000920	tetramer interface [polypeptide binding]; other site
1055528000921	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1055528000922	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528000923	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528000924	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1055528000925	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1055528000926	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1055528000927	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055528000928	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1055528000929	putative substrate translocation pore; other site
1055528000930	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1055528000931	hexamer interface [polypeptide binding]; other site
1055528000932	active site 2 [active]
1055528000933	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
1055528000934	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
1055528000935	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1055528000936	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1055528000937	arginyl-tRNA synthetase; Region: argS; TIGR00456
1055528000938	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1055528000939	active site
1055528000940	HIGH motif; other site
1055528000941	KMSK motif region; other site
1055528000942	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1055528000943	tRNA binding surface [nucleotide binding]; other site
1055528000944	anticodon binding site; other site
1055528000945	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1055528000946	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1055528000947	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1055528000948	catalytic site [active]
1055528000949	G-X2-G-X-G-K; other site
1055528000950	nuclease NucT; Provisional; Region: PRK13912
1055528000951	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
1055528000952	putative active site [active]
1055528000953	catalytic site [active]
1055528000954	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528000955	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1055528000956	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1055528000957	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1055528000958	ligand binding site; other site
1055528000959	tetramer interface; other site
1055528000960	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
1055528000961	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
1055528000962	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1055528000963	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1055528000964	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1055528000965	NAD synthetase; Provisional; Region: PRK13980
1055528000966	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1055528000967	homodimer interface [polypeptide binding]; other site
1055528000968	NAD binding pocket [chemical binding]; other site
1055528000969	ATP binding pocket [chemical binding]; other site
1055528000970	Mg binding site [ion binding]; other site
1055528000971	active-site loop [active]
1055528000972	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1055528000973	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1055528000974	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1055528000975	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1055528000976	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1055528000977	Switch I; other site
1055528000978	Switch II; other site
1055528000979	cell division topological specificity factor MinE; Region: minE; TIGR01215
1055528000980	DNA protecting protein DprA; Region: dprA; TIGR00732
1055528000981	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1055528000982	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1055528000983	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528000984	Sel1 repeat; Region: Sel1; cl02723
1055528000985	Sel1-like repeats; Region: SEL1; smart00671
1055528000986	Sel1-like repeats; Region: SEL1; smart00671
1055528000987	Sel1-like repeats; Region: SEL1; smart00671
1055528000988	chlorohydrolase; Provisional; Region: PRK07213
1055528000989	Predicted membrane protein [Function unknown]; Region: COG3326
1055528000990	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1055528000991	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1055528000992	active site
1055528000993	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1055528000994	DHH family; Region: DHH; pfam01368
1055528000995	DHHA1 domain; Region: DHHA1; pfam02272
1055528000996	CTP synthetase; Validated; Region: pyrG; PRK05380
1055528000997	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1055528000998	Catalytic site [active]
1055528000999	active site
1055528001000	UTP binding site [chemical binding]; other site
1055528001001	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1055528001002	active site
1055528001003	putative oxyanion hole; other site
1055528001004	catalytic triad [active]
1055528001005	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1055528001006	active site
1055528001007	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
1055528001008	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1055528001009	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1055528001010	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1055528001011	FliG C-terminal domain; Region: FliG_C; pfam01706
1055528001012	flagellar assembly protein H; Validated; Region: fliH; PRK06669
1055528001013	Flagellar assembly protein FliH; Region: FliH; pfam02108
1055528001014	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1055528001015	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1055528001016	TPP-binding site; other site
1055528001017	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1055528001018	PYR/PP interface [polypeptide binding]; other site
1055528001019	dimer interface [polypeptide binding]; other site
1055528001020	TPP binding site [chemical binding]; other site
1055528001021	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1055528001022	GTP-binding protein LepA; Provisional; Region: PRK05433
1055528001023	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1055528001024	G1 box; other site
1055528001025	putative GEF interaction site [polypeptide binding]; other site
1055528001026	GTP/Mg2+ binding site [chemical binding]; other site
1055528001027	Switch I region; other site
1055528001028	G2 box; other site
1055528001029	G3 box; other site
1055528001030	Switch II region; other site
1055528001031	G4 box; other site
1055528001032	G5 box; other site
1055528001033	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1055528001034	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1055528001035	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1055528001036	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
1055528001037	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1055528001038	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1055528001039	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1055528001040	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055528001041	putative substrate translocation pore; other site
1055528001042	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1055528001043	TspO/MBR family; Region: TspO_MBR; cl01379
1055528001044	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1055528001045	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1055528001046	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
1055528001047	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1055528001048	TPP-binding site [chemical binding]; other site
1055528001049	dimer interface [polypeptide binding]; other site
1055528001050	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1055528001051	PYR/PP interface [polypeptide binding]; other site
1055528001052	dimer interface [polypeptide binding]; other site
1055528001053	TPP binding site [chemical binding]; other site
1055528001054	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1055528001055	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1055528001056	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
1055528001057	active site
1055528001058	Riboflavin kinase; Region: Flavokinase; smart00904
1055528001059	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055528001060	hemolysin TlyA family protein; Region: tly; TIGR00478
1055528001061	RNA binding surface [nucleotide binding]; other site
1055528001062	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528001063	S-adenosylmethionine binding site [chemical binding]; other site
1055528001064	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1055528001065	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1055528001066	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1055528001067	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528001068	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1055528001069	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1055528001070	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528001071	Walker A/P-loop; other site
1055528001072	ATP binding site [chemical binding]; other site
1055528001073	Q-loop/lid; other site
1055528001074	ABC transporter signature motif; other site
1055528001075	Walker B; other site
1055528001076	D-loop; other site
1055528001077	H-loop/switch region; other site
1055528001078	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
1055528001079	Restriction endonuclease; Region: Mrr_cat; pfam04471
1055528001080	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1055528001081	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
1055528001082	active site
1055528001083	Zn binding site [ion binding]; other site
1055528001084	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1055528001085	metal-binding site [ion binding]
1055528001086	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1055528001087	metal-binding site [ion binding]
1055528001088	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
1055528001089	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1055528001090	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1055528001091	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1055528001092	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1055528001093	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1055528001094	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528001095	Walker A motif; other site
1055528001096	ATP binding site [chemical binding]; other site
1055528001097	Walker B motif; other site
1055528001098	arginine finger; other site
1055528001099	Peptidase family M41; Region: Peptidase_M41; pfam01434
1055528001100	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1055528001101	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1055528001102	S-adenosylmethionine binding site [chemical binding]; other site
1055528001103	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055528001104	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528001105	active site
1055528001106	phosphorylation site [posttranslational modification]
1055528001107	intermolecular recognition site; other site
1055528001108	dimerization interface [polypeptide binding]; other site
1055528001109	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001110	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
1055528001111	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
1055528001112	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1055528001113	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1055528001114	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1055528001115	sec-independent translocase; Provisional; Region: PRK04098
1055528001116	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1055528001117	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528001118	Walker A motif; other site
1055528001119	ATP binding site [chemical binding]; other site
1055528001120	Walker B motif; other site
1055528001121	arginine finger; other site
1055528001122	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1055528001123	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1055528001124	oligomerization interface [polypeptide binding]; other site
1055528001125	active site
1055528001126	metal binding site [ion binding]; metal-binding site
1055528001127	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001128	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001129	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055528001130	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055528001131	septum formation inhibitor; Reviewed; Region: minC; PRK00556
1055528001132	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1055528001133	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
1055528001134	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1055528001135	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1055528001136	homoserine kinase; Region: thrB; TIGR00191
1055528001137	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1055528001138	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
1055528001139	putative RNA binding cleft [nucleotide binding]; other site
1055528001140	potential frameshift: common BLAST hit: gi|188527209|ref|YP_001909896.1| translation initiation factor IF-2
1055528001141	Ribosome-binding factor A; Region: RBFA; cl00542
1055528001142	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
1055528001143	Sm and related proteins; Region: Sm_like; cl00259
1055528001144	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1055528001145	putative oligomer interface [polypeptide binding]; other site
1055528001146	putative RNA binding site [nucleotide binding]; other site
1055528001147	potential frameshift: common BLAST hit: gi|254779092|ref|YP_003057197.1| acetyl-CoA synthetase
1055528001148	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1055528001149	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1055528001150	putative active site [active]
1055528001151	putative metal binding site [ion binding]; other site
1055528001152	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1055528001153	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528001154	active site
1055528001155	intermolecular recognition site; other site
1055528001156	dimerization interface [polypeptide binding]; other site
1055528001157	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1055528001158	DNA binding site [nucleotide binding]
1055528001159	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
1055528001160	DHH family; Region: DHH; pfam01368
1055528001161	flagellar biosynthesis protein FlhA; Region: FlhA; TIGR01398
1055528001162	FHIPEP family; Region: FHIPEP; pfam00771
1055528001163	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1055528001164	16S/18S rRNA binding site [nucleotide binding]; other site
1055528001165	S13e-L30e interaction site [polypeptide binding]; other site
1055528001166	25S rRNA binding site [nucleotide binding]; other site
1055528001167	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1055528001168	O-Antigen ligase; Region: Wzy_C; pfam04932
1055528001169	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1055528001170	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1055528001171	trimer interface [polypeptide binding]; other site
1055528001172	active site
1055528001173	dimer interface [polypeptide binding]; other site
1055528001174	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1055528001175	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1055528001176	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1055528001177	active site
1055528001178	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1055528001179	catalytic center binding site [active]
1055528001180	ATP binding site [chemical binding]; other site
1055528001181	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
1055528001182	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1055528001183	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1055528001184	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1055528001185	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1055528001186	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1055528001187	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1055528001188	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1055528001189	DNA binding residues [nucleotide binding]
1055528001190	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1055528001191	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1055528001192	flagellar motor switch protein FliY; Validated; Region: PRK08432
1055528001193	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1055528001194	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1055528001195	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4731
1055528001196	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1055528001197	metal binding site 2 [ion binding]; metal-binding site
1055528001198	putative DNA binding helix; other site
1055528001199	metal binding site 1 [ion binding]; metal-binding site
1055528001200	dimer interface [polypeptide binding]; other site
1055528001201	structural Zn2+ binding site [ion binding]; other site
1055528001202	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
1055528001203	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528001204	Walker A motif; other site
1055528001205	ATP binding site [chemical binding]; other site
1055528001206	Walker B motif; other site
1055528001207	arginine finger; other site
1055528001208	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1055528001209	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
1055528001210	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1055528001211	DNA binding residues [nucleotide binding]
1055528001212	putative dimer interface [polypeptide binding]; other site
1055528001213	chaperone protein DnaJ; Provisional; Region: PRK14299
1055528001214	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1055528001215	HSP70 interaction site [polypeptide binding]; other site
1055528001216	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1055528001217	substrate binding site [polypeptide binding]; other site
1055528001218	dimer interface [polypeptide binding]; other site
1055528001219	5'-3' exonuclease; Provisional; Region: PRK14976
1055528001220	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1055528001221	putative active site [active]
1055528001222	Helix-hairpin-helix class 2 (Pol1 family) motifs; Region: HhH2; smart00279
1055528001223	DNA binding site [nucleotide binding]
1055528001224	metal binding site [ion binding]; metal-binding site
1055528001225	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055528001226	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528001227	active site
1055528001228	dimerization interface [polypeptide binding]; other site
1055528001229	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
1055528001230	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1055528001231	substrate binding site; other site
1055528001232	dimer interface; other site
1055528001233	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1055528001234	homotrimer interaction site [polypeptide binding]; other site
1055528001235	zinc binding site [ion binding]; other site
1055528001236	CDP-binding sites; other site
1055528001237	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1055528001238	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1055528001239	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1055528001240	protein binding site [polypeptide binding]; other site
1055528001241	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1055528001242	protein binding site [polypeptide binding]; other site
1055528001243	S-methylmethionine transporter; Provisional; Region: PRK11387
1055528001244	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
1055528001245	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
1055528001246	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
1055528001247	putative NAD(P) binding site [chemical binding]; other site
1055528001248	active site
1055528001249	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1055528001250	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1055528001251	dimer interface [polypeptide binding]; other site
1055528001252	active site
1055528001253	catalytic residue [active]
1055528001254	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1055528001255	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1055528001256	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1055528001257	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
1055528001258	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1055528001259	quinone interaction residues [chemical binding]; other site
1055528001260	active site
1055528001261	catalytic residues [active]
1055528001262	FMN binding site [chemical binding]; other site
1055528001263	substrate binding site [chemical binding]; other site
1055528001264	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1055528001265	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1055528001266	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1055528001267	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
1055528001268	putative domain interface [polypeptide binding]; other site
1055528001269	putative active site [active]
1055528001270	catalytic site [active]
1055528001271	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1055528001272	putative active site [active]
1055528001273	putative domain interface [polypeptide binding]; other site
1055528001274	catalytic site [active]
1055528001275	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528001276	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055528001277	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528001278	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055528001279	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1055528001280	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055528001281	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1055528001282	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1055528001283	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528001284	ATP binding site [chemical binding]; other site
1055528001285	putative Mg++ binding site [ion binding]; other site
1055528001286	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1055528001287	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1055528001288	putative metal binding site [ion binding]; other site
1055528001289	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
1055528001290	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1055528001291	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
1055528001292	active site
1055528001293	Zn binding site [ion binding]; other site
1055528001294	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1055528001295	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1055528001296	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001297	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1055528001298	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1055528001299	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1055528001300	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528001301	dimer interface [polypeptide binding]; other site
1055528001302	conserved gate region; other site
1055528001303	putative PBP binding loops; other site
1055528001304	ABC-ATPase subunit interface; other site
1055528001305	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1055528001306	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528001307	Walker A/P-loop; other site
1055528001308	ATP binding site [chemical binding]; other site
1055528001309	Q-loop/lid; other site
1055528001310	ABC transporter signature motif; other site
1055528001311	Walker B; other site
1055528001312	D-loop; other site
1055528001313	H-loop/switch region; other site
1055528001314	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1055528001315	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1055528001316	active site
1055528001317	HIGH motif; other site
1055528001318	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1055528001319	active site
1055528001320	KMSKS motif; other site
1055528001321	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001322	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055528001323	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
1055528001324	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1055528001325	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1055528001326	G1 box; other site
1055528001327	putative GEF interaction site [polypeptide binding]; other site
1055528001328	GTP/Mg2+ binding site [chemical binding]; other site
1055528001329	Switch I region; other site
1055528001330	G2 box; other site
1055528001331	G3 box; other site
1055528001332	Switch II region; other site
1055528001333	G4 box; other site
1055528001334	G5 box; other site
1055528001335	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1055528001336	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1055528001337	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
1055528001338	Catalytic GIY-YIG domain of coliphage T4 non-specific endonuclease II, type II restriction endonuclease R.Hpy188I, and similar proteins; Region: GIY-YIG_EndoII_Hpy188I_like; cd10436
1055528001339	GIY-YIG motif/motif A; other site
1055528001340	DNA binding site [nucleotide binding]
1055528001341	active site
1055528001342	catalytic site [active]
1055528001343	metal binding site [ion binding]; metal-binding site
1055528001344	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1055528001345	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055528001346	cofactor binding site; other site
1055528001347	DNA binding site [nucleotide binding]
1055528001348	substrate interaction site [chemical binding]; other site
1055528001349	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1055528001350	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
1055528001351	putative heme binding pocket [chemical binding]; other site
1055528001352	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528001353	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528001354	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
1055528001355	Cation transport protein; Region: TrkH; cl17365
1055528001356	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1055528001357	TrkA-N domain; Region: TrkA_N; pfam02254
1055528001358	TrkA-C domain; Region: TrkA_C; pfam02080
1055528001359	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1055528001360	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1055528001361	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
1055528001362	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1055528001363	Mg++ binding site [ion binding]; other site
1055528001364	putative catalytic motif [active]
1055528001365	putative substrate binding site [chemical binding]; other site
1055528001366	potential frameshift: common BLAST hit: gi|188527667|ref|YP_001910354.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
1055528001367	Protein of unknown function (DUF493); Region: DUF493; pfam04359
1055528001368	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1055528001369	active site
1055528001370	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1055528001371	Na2 binding site [ion binding]; other site
1055528001372	putative substrate binding site 1 [chemical binding]; other site
1055528001373	Na binding site 1 [ion binding]; other site
1055528001374	putative substrate binding site 2 [chemical binding]; other site
1055528001375	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1055528001376	Na2 binding site [ion binding]; other site
1055528001377	putative substrate binding site 1 [chemical binding]; other site
1055528001378	Na binding site 1 [ion binding]; other site
1055528001379	putative substrate binding site 2 [chemical binding]; other site
1055528001380	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1055528001381	dimerization interface [polypeptide binding]; other site
1055528001382	substrate binding site [chemical binding]; other site
1055528001383	active site
1055528001384	calcium binding site [ion binding]; other site
1055528001385	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
1055528001386	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1055528001387	putative DNA binding surface [nucleotide binding]; other site
1055528001388	dimer interface [polypeptide binding]; other site
1055528001389	beta-clamp/clamp loader binding surface; other site
1055528001390	beta-clamp/translesion DNA polymerase binding surface; other site
1055528001391	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1055528001392	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055528001393	Mg2+ binding site [ion binding]; other site
1055528001394	G-X-G motif; other site
1055528001395	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1055528001396	anchoring element; other site
1055528001397	dimer interface [polypeptide binding]; other site
1055528001398	ATP binding site [chemical binding]; other site
1055528001399	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1055528001400	active site
1055528001401	putative metal-binding site [ion binding]; other site
1055528001402	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1055528001403	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055528001404	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055528001405	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1055528001406	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1055528001407	dimer interface [polypeptide binding]; other site
1055528001408	ADP-ribose binding site [chemical binding]; other site
1055528001409	active site
1055528001410	nudix motif; other site
1055528001411	metal binding site [ion binding]; metal-binding site
1055528001412	FAD binding domain; Region: FAD_binding_4; pfam01565
1055528001413	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
1055528001414	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
1055528001415	dihydrodipicolinate reductase; Region: dapB; TIGR00036
1055528001416	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1055528001417	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1055528001418	glutamine synthetase, type I; Region: GlnA; TIGR00653
1055528001419	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1055528001420	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1055528001421	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055528001422	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055528001423	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1055528001424	Uncharacterized conserved protein [Function unknown]; Region: COG3586
1055528001425	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1055528001426	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1055528001427	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1055528001428	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1055528001429	active site
1055528001430	HslU subunit interaction site [polypeptide binding]; other site
1055528001431	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1055528001432	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528001433	Walker A motif; other site
1055528001434	ATP binding site [chemical binding]; other site
1055528001435	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528001436	Walker B motif; other site
1055528001437	arginine finger; other site
1055528001438	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1055528001439	GTPase Era; Reviewed; Region: era; PRK00089
1055528001440	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1055528001441	G1 box; other site
1055528001442	GTP/Mg2+ binding site [chemical binding]; other site
1055528001443	Switch I region; other site
1055528001444	G2 box; other site
1055528001445	Switch II region; other site
1055528001446	G3 box; other site
1055528001447	G4 box; other site
1055528001448	G5 box; other site
1055528001449	KH domain; Region: KH_2; pfam07650
1055528001450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1055528001451	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528001452	Sel1-like repeats; Region: SEL1; smart00671
1055528001453	potential frameshift: common BLAST hit: gi|188527639|ref|YP_001910326.1| cag pathogenicity island protein (cag beta, cag5)
1055528001454	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1055528001455	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1055528001456	ATP binding site [chemical binding]; other site
1055528001457	Walker A motif; other site
1055528001458	hexamer interface [polypeptide binding]; other site
1055528001459	Walker B motif; other site
1055528001460	CagZ; Region: CagZ; pfam09053
1055528001461	DC-EC Repeat; Region: CagY_M; pfam07337
1055528001462	DC-EC Repeat; Region: CagY_M; pfam07337
1055528001463	DC-EC Repeat; Region: CagY_M; pfam07337
1055528001464	DC-EC Repeat; Region: CagY_M; pfam07337
1055528001465	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1055528001466	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
1055528001467	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1055528001468	VirB7 interaction site; other site
1055528001469	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1055528001470	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
1055528001471	prolyl-tRNA synthetase; Provisional; Region: PRK08661
1055528001472	potential frameshift: common BLAST hit: gi|15645170|ref|NP_207340.1| cag pathogenicity island protein (cag23)
1055528001473	CagA exotoxin; Region: CagA; pfam03507
1055528001474	MarR family; Region: MarR_2; cl17246
1055528001475	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1055528001476	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1055528001477	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1055528001478	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1055528001479	RNA binding site [nucleotide binding]; other site
1055528001480	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1055528001481	multimer interface [polypeptide binding]; other site
1055528001482	Walker A motif; other site
1055528001483	ATP binding site [chemical binding]; other site
1055528001484	Walker B motif; other site
1055528001485	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
1055528001486	Predicted methyltransferases [General function prediction only]; Region: COG0313
1055528001487	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1055528001488	putative SAM binding site [chemical binding]; other site
1055528001489	putative homodimer interface [polypeptide binding]; other site
1055528001490	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1055528001491	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1055528001492	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1055528001493	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
1055528001494	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1055528001495	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
1055528001496	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1055528001497	dimer interface [polypeptide binding]; other site
1055528001498	active site
1055528001499	acyl carrier protein; Provisional; Region: acpP; PRK00982
1055528001500	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1055528001501	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1055528001502	NAD(P) binding site [chemical binding]; other site
1055528001503	active site
1055528001504	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1055528001505	Phosphatidylinositol-specific phospholipase C, Y domain; Region: PI-PLC-Y; cl14781
1055528001506	Predicted membrane protein [Function unknown]; Region: COG3059
1055528001507	diaminopimelate epimerase; Region: DapF; TIGR00652
1055528001508	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1055528001509	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1055528001510	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1055528001511	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1055528001512	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1055528001513	GTP-binding protein YchF; Reviewed; Region: PRK09601
1055528001514	YchF GTPase; Region: YchF; cd01900
1055528001515	G1 box; other site
1055528001516	GTP/Mg2+ binding site [chemical binding]; other site
1055528001517	Switch I region; other site
1055528001518	G2 box; other site
1055528001519	Switch II region; other site
1055528001520	G3 box; other site
1055528001521	G4 box; other site
1055528001522	G5 box; other site
1055528001523	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1055528001524	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1055528001525	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1055528001526	interface (dimer of trimers) [polypeptide binding]; other site
1055528001527	Substrate-binding/catalytic site; other site
1055528001528	Zn-binding sites [ion binding]; other site
1055528001529	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1055528001530	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055528001531	active site
1055528001532	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1055528001533	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
1055528001534	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1055528001535	Peptidase family M50; Region: Peptidase_M50; pfam02163
1055528001536	active site
1055528001537	putative substrate binding region [chemical binding]; other site
1055528001538	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1055528001539	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1055528001540	Catalytic site [active]
1055528001541	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1055528001542	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
1055528001543	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1055528001544	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1055528001545	homodimer interface [polypeptide binding]; other site
1055528001546	NADP binding site [chemical binding]; other site
1055528001547	substrate binding site [chemical binding]; other site
1055528001548	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1055528001549	Sulfatase; Region: Sulfatase; pfam00884
1055528001550	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1055528001551	BNR repeat-like domain; Region: BNR_2; pfam13088
1055528001552	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1055528001553	active site
1055528001554	substrate binding pocket [chemical binding]; other site
1055528001555	dimer interface [polypeptide binding]; other site
1055528001556	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1055528001557	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
1055528001558	flagellar motor switch protein; Validated; Region: PRK08433
1055528001559	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1055528001560	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1055528001561	minor groove reading motif; other site
1055528001562	helix-hairpin-helix signature motif; other site
1055528001563	substrate binding pocket [chemical binding]; other site
1055528001564	active site
1055528001565	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1055528001566	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1055528001567	Protein of unknown function; Region: DUF3971; pfam13116
1055528001568	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
1055528001569	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1055528001570	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1055528001571	dimerization interface [polypeptide binding]; other site
1055528001572	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
1055528001573	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1055528001574	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
1055528001575	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1055528001576	dimer interface [polypeptide binding]; other site
1055528001577	PYR/PP interface [polypeptide binding]; other site
1055528001578	TPP binding site [chemical binding]; other site
1055528001579	substrate binding site [chemical binding]; other site
1055528001580	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
1055528001581	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1055528001582	TPP-binding site [chemical binding]; other site
1055528001583	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
1055528001584	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1055528001585	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1055528001586	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
1055528001587	Transglycosylase; Region: Transgly; pfam00912
1055528001588	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1055528001589	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1055528001590	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
1055528001591	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1055528001592	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055528001593	catalytic residue [active]
1055528001594	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1055528001595	dimer interface [polypeptide binding]; other site
1055528001596	putative CheW interface [polypeptide binding]; other site
1055528001597	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1055528001598	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1055528001599	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1055528001600	Walker A/P-loop; other site
1055528001601	ATP binding site [chemical binding]; other site
1055528001602	Q-loop/lid; other site
1055528001603	ABC transporter signature motif; other site
1055528001604	Walker B; other site
1055528001605	D-loop; other site
1055528001606	H-loop/switch region; other site
1055528001607	flagellin A; Reviewed; Region: PRK12584
1055528001608	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1055528001609	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055528001610	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055528001611	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1055528001612	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
1055528001613	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1055528001614	minor groove reading motif; other site
1055528001615	helix-hairpin-helix signature motif; other site
1055528001616	active site
1055528001617	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1055528001618	substrate binding site [chemical binding]; other site
1055528001619	active site
1055528001620	Outer membrane efflux protein; Region: OEP; pfam02321
1055528001621	Outer membrane efflux protein; Region: OEP; pfam02321
1055528001622	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1055528001623	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055528001624	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
1055528001625	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001626	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1055528001627	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055528001628	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055528001629	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055528001630	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055528001631	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1055528001632	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055528001633	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1055528001634	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1055528001635	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528001636	Walker A/P-loop; other site
1055528001637	ATP binding site [chemical binding]; other site
1055528001638	Q-loop/lid; other site
1055528001639	ABC transporter signature motif; other site
1055528001640	Walker B; other site
1055528001641	D-loop; other site
1055528001642	H-loop/switch region; other site
1055528001643	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1055528001644	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1055528001645	nucleotide binding pocket [chemical binding]; other site
1055528001646	K-X-D-G motif; other site
1055528001647	catalytic site [active]
1055528001648	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1055528001649	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1055528001650	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1055528001651	Dimer interface [polypeptide binding]; other site
1055528001652	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
1055528001653	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055528001654	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528001655	active site
1055528001656	phosphorylation site [posttranslational modification]
1055528001657	intermolecular recognition site; other site
1055528001658	dimerization interface [polypeptide binding]; other site
1055528001659	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1055528001660	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1055528001661	dimer interface [polypeptide binding]; other site
1055528001662	anticodon binding site; other site
1055528001663	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1055528001664	homodimer interface [polypeptide binding]; other site
1055528001665	motif 1; other site
1055528001666	active site
1055528001667	motif 2; other site
1055528001668	GAD domain; Region: GAD; pfam02938
1055528001669	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1055528001670	active site
1055528001671	motif 3; other site
1055528001672	adenylate kinase; Reviewed; Region: adk; PRK00279
1055528001673	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1055528001674	AMP-binding site [chemical binding]; other site
1055528001675	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1055528001676	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055528001677	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
1055528001678	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055528001679	Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG3306
1055528001680	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1055528001681	dimer interface [polypeptide binding]; other site
1055528001682	substrate binding site [chemical binding]; other site
1055528001683	metal binding sites [ion binding]; metal-binding site
1055528001684	MutS2 family protein; Region: mutS2; TIGR01069
1055528001685	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
1055528001686	Walker A/P-loop; other site
1055528001687	ATP binding site [chemical binding]; other site
1055528001688	Q-loop/lid; other site
1055528001689	ABC transporter signature motif; other site
1055528001690	Walker B; other site
1055528001691	D-loop; other site
1055528001692	H-loop/switch region; other site
1055528001693	Smr domain; Region: Smr; pfam01713
1055528001694	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
1055528001695	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1055528001696	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055528001697	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1055528001698	hypothetical protein; Provisional; Region: PRK05839
1055528001699	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1055528001700	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528001701	homodimer interface [polypeptide binding]; other site
1055528001702	catalytic residue [active]
1055528001703	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1055528001704	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1055528001705	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1055528001706	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
1055528001707	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
1055528001708	putative trimer interface [polypeptide binding]; other site
1055528001709	putative CoA binding site [chemical binding]; other site
1055528001710	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528001711	Sel1-like repeats; Region: SEL1; smart00671
1055528001712	Sel1-like repeats; Region: SEL1; smart00671
1055528001713	Sel1 repeat; Region: Sel1; cl02723
1055528001714	Sel1-like repeats; Region: SEL1; smart00671
1055528001715	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055528001716	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055528001717	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1055528001718	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1055528001719	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1055528001720	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1055528001721	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1055528001722	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
1055528001723	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
1055528001724	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1055528001725	nickel binding site [ion binding]; other site
1055528001726	putative substrate-binding site; other site
1055528001727	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001728	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
1055528001729	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
1055528001730	Uncharacterized conserved protein [Function unknown]; Region: COG1912
1055528001731	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
1055528001732	MraW methylase family; Region: Methyltransf_5; cl17771
1055528001733	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001734	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1055528001735	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1055528001736	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1055528001737	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1055528001738	Response regulator receiver domain; Region: Response_reg; pfam00072
1055528001739	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528001740	active site
1055528001741	phosphorylation site [posttranslational modification]
1055528001742	intermolecular recognition site; other site
1055528001743	dimerization interface [polypeptide binding]; other site
1055528001744	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528001745	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1055528001746	Walker A motif; other site
1055528001747	ATP binding site [chemical binding]; other site
1055528001748	Walker B motif; other site
1055528001749	arginine finger; other site
1055528001750	DNA gyrase subunit A; Validated; Region: PRK05560
1055528001751	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1055528001752	CAP-like domain; other site
1055528001753	active site
1055528001754	primary dimer interface [polypeptide binding]; other site
1055528001755	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055528001756	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055528001757	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055528001758	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055528001759	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055528001760	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1055528001761	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1055528001762	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
1055528001763	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
1055528001764	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
1055528001765	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
1055528001766	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
1055528001767	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
1055528001768	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
1055528001769	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
1055528001770	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1055528001771	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
1055528001772	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1055528001773	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1055528001774	putative acyltransferase; Provisional; Region: PRK05790
1055528001775	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1055528001776	dimer interface [polypeptide binding]; other site
1055528001777	active site
1055528001778	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
1055528001779	active site
1055528001780	catalytic site [active]
1055528001781	substrate binding site [chemical binding]; other site
1055528001782	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
1055528001783	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1055528001784	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1055528001785	G1 box; other site
1055528001786	GTP/Mg2+ binding site [chemical binding]; other site
1055528001787	Switch I region; other site
1055528001788	G2 box; other site
1055528001789	G3 box; other site
1055528001790	Switch II region; other site
1055528001791	G4 box; other site
1055528001792	G5 box; other site
1055528001793	Nucleoside recognition; Region: Gate; pfam07670
1055528001794	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1055528001795	Nucleoside recognition; Region: Gate; pfam07670
1055528001796	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1055528001797	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1055528001798	N-terminal plug; other site
1055528001799	ligand-binding site [chemical binding]; other site
1055528001800	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1055528001801	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
1055528001802	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1055528001803	Substrate binding site; other site
1055528001804	Mg++ binding site; other site
1055528001805	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1055528001806	active site
1055528001807	substrate binding site [chemical binding]; other site
1055528001808	CoA binding site [chemical binding]; other site
1055528001809	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
1055528001810	ATP cone domain; Region: ATP-cone; pfam03477
1055528001811	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1055528001812	active site
1055528001813	dimer interface [polypeptide binding]; other site
1055528001814	catalytic residues [active]
1055528001815	effector binding site; other site
1055528001816	R2 peptide binding site; other site
1055528001817	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1055528001818	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1055528001819	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1055528001820	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1055528001821	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1055528001822	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1055528001823	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1055528001824	DNA binding site [nucleotide binding]
1055528001825	active site
1055528001826	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1055528001827	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1055528001828	active site
1055528001829	DNA binding site [nucleotide binding]
1055528001830	Int/Topo IB signature motif; other site
1055528001831	aspartate aminotransferase; Provisional; Region: PRK05764
1055528001832	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1055528001833	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528001834	homodimer interface [polypeptide binding]; other site
1055528001835	catalytic residue [active]
1055528001836	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001837	Predicted helicase [General function prediction only]; Region: COG4889
1055528001838	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055528001839	nucleotide binding region [chemical binding]; other site
1055528001840	ATP-binding site [chemical binding]; other site
1055528001841	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
1055528001842	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528001843	ATP binding site [chemical binding]; other site
1055528001844	putative Mg++ binding site [ion binding]; other site
1055528001845	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1055528001846	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1055528001847	Cysteine-rich domain; Region: CCG; pfam02754
1055528001848	Cysteine-rich domain; Region: CCG; pfam02754
1055528001849	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
1055528001850	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528001851	FeS/SAM binding site; other site
1055528001852	HemN C-terminal domain; Region: HemN_C; pfam06969
1055528001853	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
1055528001854	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1055528001855	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1055528001856	Tetramer interface [polypeptide binding]; other site
1055528001857	active site
1055528001858	FMN-binding site [chemical binding]; other site
1055528001859	ribonuclease III; Reviewed; Region: rnc; PRK00102
1055528001860	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1055528001861	dimerization interface [polypeptide binding]; other site
1055528001862	active site
1055528001863	metal binding site [ion binding]; metal-binding site
1055528001864	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1055528001865	dsRNA binding site [nucleotide binding]; other site
1055528001866	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1055528001867	RNA/DNA hybrid binding site [nucleotide binding]; other site
1055528001868	active site
1055528001869	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1055528001870	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
1055528001871	SurA N-terminal domain; Region: SurA_N; pfam09312
1055528001872	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1055528001873	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1055528001874	GatB domain; Region: GatB_Yqey; smart00845
1055528001875	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1055528001876	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1055528001877	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1055528001878	hypothetical protein; Provisional; Region: PRK08445
1055528001879	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528001880	FeS/SAM binding site; other site
1055528001881	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1055528001882	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055528001883	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055528001884	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055528001885	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1055528001886	Surface antigen; Region: Bac_surface_Ag; pfam01103
1055528001887	hypothetical protein; Provisional; Region: PRK08444
1055528001888	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528001889	FeS/SAM binding site; other site
1055528001890	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1055528001891	Ferritin-like domain; Region: Ferritin; pfam00210
1055528001892	ferroxidase diiron center [ion binding]; other site
1055528001893	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1055528001894	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055528001895	motif II; other site
1055528001896	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
1055528001897	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
1055528001898	ligand binding site [chemical binding]; other site
1055528001899	active site
1055528001900	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1055528001901	Aspartase; Region: Aspartase; cd01357
1055528001902	active sites [active]
1055528001903	tetramer interface [polypeptide binding]; other site
1055528001904	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1055528001905	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1055528001906	hinge; other site
1055528001907	active site
1055528001908	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1055528001909	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1055528001910	active site
1055528001911	tetramer interface; other site
1055528001912	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1055528001913	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1055528001914	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1055528001915	catalytic residue [active]
1055528001916	YGGT family; Region: YGGT; pfam02325
1055528001917	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
1055528001918	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1055528001919	active site
1055528001920	HIGH motif; other site
1055528001921	nucleotide binding site [chemical binding]; other site
1055528001922	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1055528001923	active site
1055528001924	KMSKS motif; other site
1055528001925	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1055528001926	dimer interface [polypeptide binding]; other site
1055528001927	FMN binding site [chemical binding]; other site
1055528001928	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1055528001929	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1055528001930	active site
1055528001931	NTP binding site [chemical binding]; other site
1055528001932	metal binding triad [ion binding]; metal-binding site
1055528001933	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1055528001934	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1055528001935	Ligand Binding Site [chemical binding]; other site
1055528001936	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001937	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1055528001938	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1055528001939	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1055528001940	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1055528001941	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1055528001942	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1055528001943	Walker A/P-loop; other site
1055528001944	ATP binding site [chemical binding]; other site
1055528001945	Q-loop/lid; other site
1055528001946	ABC transporter signature motif; other site
1055528001947	Walker B; other site
1055528001948	D-loop; other site
1055528001949	H-loop/switch region; other site
1055528001950	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1055528001951	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
1055528001952	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528001953	Walker A motif; other site
1055528001954	ATP binding site [chemical binding]; other site
1055528001955	Walker B motif; other site
1055528001956	arginine finger; other site
1055528001957	Lysine efflux permease [General function prediction only]; Region: COG1279
1055528001958	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1055528001959	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
1055528001960	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1055528001961	active site
1055528001962	homodimer interface [polypeptide binding]; other site
1055528001963	homotetramer interface [polypeptide binding]; other site
1055528001964	anaerobic c4-dicarboxylate membrane transporter family protein; Region: Dcu; TIGR00770
1055528001965	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1055528001966	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528001967	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
1055528001968	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1055528001969	FMN binding site [chemical binding]; other site
1055528001970	active site
1055528001971	catalytic residues [active]
1055528001972	substrate binding site [chemical binding]; other site
1055528001973	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1055528001974	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1055528001975	Ligand Binding Site [chemical binding]; other site
1055528001976	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1055528001977	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1055528001978	G1 box; other site
1055528001979	GTP/Mg2+ binding site [chemical binding]; other site
1055528001980	G2 box; other site
1055528001981	Switch I region; other site
1055528001982	G3 box; other site
1055528001983	Switch II region; other site
1055528001984	G4 box; other site
1055528001985	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1055528001986	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1055528001987	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528001988	FeS/SAM binding site; other site
1055528001989	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
1055528001990	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055528001991	active site
1055528001992	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1055528001993	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055528001994	catalytic residue [active]
1055528001995	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1055528001996	tetramer interfaces [polypeptide binding]; other site
1055528001997	binuclear metal-binding site [ion binding]; other site
1055528001998	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1055528001999	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1055528002000	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1055528002001	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1055528002002	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1055528002003	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055528002004	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
1055528002005	nucleotide binding site/active site [active]
1055528002006	HIT family signature motif; other site
1055528002007	catalytic residue [active]
1055528002008	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1055528002009	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1055528002010	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055528002011	active site
1055528002012	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1055528002013	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1055528002014	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1055528002015	active site
1055528002016	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
1055528002017	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
1055528002018	Interdomain contacts; other site
1055528002019	Cytokine receptor motif; other site
1055528002020	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1055528002021	Interdomain contacts; other site
1055528002022	Cytokine receptor motif; other site
1055528002023	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1055528002024	Interdomain contacts; other site
1055528002025	Cytokine receptor motif; other site
1055528002026	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528002027	S-adenosylmethionine binding site [chemical binding]; other site
1055528002028	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1055528002029	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1055528002030	Walker A/P-loop; other site
1055528002031	ATP binding site [chemical binding]; other site
1055528002032	Q-loop/lid; other site
1055528002033	ABC transporter signature motif; other site
1055528002034	Walker B; other site
1055528002035	D-loop; other site
1055528002036	H-loop/switch region; other site
1055528002037	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1055528002038	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055528002039	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055528002040	flagellar protein FlaG; Provisional; Region: PRK08452
1055528002041	flagellar capping protein; Validated; Region: fliD; PRK08453
1055528002042	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1055528002043	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1055528002044	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
1055528002045	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1055528002046	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1055528002047	putative ATP binding site [chemical binding]; other site
1055528002048	putative substrate interface [chemical binding]; other site
1055528002049	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1055528002050	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
1055528002051	putative active site; other site
1055528002052	catalytic triad [active]
1055528002053	putative dimer interface [polypeptide binding]; other site
1055528002054	Predicted permease [General function prediction only]; Region: COG2056
1055528002055	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1055528002056	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1055528002057	putative efflux protein, MATE family; Region: matE; TIGR00797
1055528002058	phosphodiesterase; Provisional; Region: PRK12704
1055528002059	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cd00105
1055528002060	nucleic acid binding region [nucleotide binding]; other site
1055528002061	G-X-X-G motif; other site
1055528002062	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1055528002063	Zn2+ binding site [ion binding]; other site
1055528002064	Mg2+ binding site [ion binding]; other site
1055528002065	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
1055528002066	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
1055528002067	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
1055528002068	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1055528002069	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1055528002070	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1055528002071	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528002072	FeS/SAM binding site; other site
1055528002073	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1055528002074	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1055528002075	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1055528002076	GTP binding site; other site
1055528002077	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
1055528002078	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1055528002079	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1055528002080	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1055528002081	active site
1055528002082	metal binding site [ion binding]; metal-binding site
1055528002083	Nitronate monooxygenase; Region: NMO; pfam03060
1055528002084	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1055528002085	FMN binding site [chemical binding]; other site
1055528002086	substrate binding site [chemical binding]; other site
1055528002087	putative catalytic residue [active]
1055528002088	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1055528002089	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1055528002090	active site
1055528002091	HIGH motif; other site
1055528002092	dimer interface [polypeptide binding]; other site
1055528002093	KMSKS motif; other site
1055528002094	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055528002095	RNA binding surface [nucleotide binding]; other site
1055528002096	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
1055528002097	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1055528002098	Zn2+ binding site [ion binding]; other site
1055528002099	Mg2+ binding site [ion binding]; other site
1055528002100	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1055528002101	synthetase active site [active]
1055528002102	NTP binding site [chemical binding]; other site
1055528002103	metal binding site [ion binding]; metal-binding site
1055528002104	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1055528002105	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
1055528002106	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1055528002107	putative nucleotide binding site [chemical binding]; other site
1055528002108	uridine monophosphate binding site [chemical binding]; other site
1055528002109	homohexameric interface [polypeptide binding]; other site
1055528002110	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
1055528002111	aconitate hydratase 2; Region: acnB; TIGR00117
1055528002112	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1055528002113	substrate binding site [chemical binding]; other site
1055528002114	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1055528002115	substrate binding site [chemical binding]; other site
1055528002116	ligand binding site [chemical binding]; other site
1055528002117	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
1055528002118	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528002119	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1055528002120	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
1055528002121	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1055528002122	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1055528002123	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055528002124	nucleotide binding region [chemical binding]; other site
1055528002125	ATP-binding site [chemical binding]; other site
1055528002126	SEC-C motif; Region: SEC-C; pfam02810
1055528002127	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1055528002128	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1055528002129	FtsX-like permease family; Region: FtsX; pfam02687
1055528002130	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528002131	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528002132	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055528002133	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528002134	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
1055528002135	metal-binding site [ion binding]
1055528002136	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1055528002137	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1055528002138	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1055528002139	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1055528002140	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1055528002141	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1055528002142	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1055528002143	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1055528002144	active site
1055528002145	catalytic residues [active]
1055528002146	metal binding site [ion binding]; metal-binding site
1055528002147	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1055528002148	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1055528002149	oligomer interface [polypeptide binding]; other site
1055528002150	active site residues [active]
1055528002151	trigger factor; Provisional; Region: tig; PRK01490
1055528002152	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1055528002153	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1055528002154	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002155	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1055528002156	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1055528002157	trimer interface [polypeptide binding]; other site
1055528002158	dimer interface [polypeptide binding]; other site
1055528002159	putative active site [active]
1055528002160	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1055528002161	MPT binding site; other site
1055528002162	trimer interface [polypeptide binding]; other site
1055528002163	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1055528002164	MoaE homodimer interface [polypeptide binding]; other site
1055528002165	MoaD interaction [polypeptide binding]; other site
1055528002166	active site residues [active]
1055528002167	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1055528002168	MoaE interaction surface [polypeptide binding]; other site
1055528002169	MoeB interaction surface [polypeptide binding]; other site
1055528002170	thiocarboxylated glycine; other site
1055528002171	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1055528002172	dimerization interface [polypeptide binding]; other site
1055528002173	active site
1055528002174	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
1055528002175	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: ribB; TIGR00506
1055528002176	GTP cyclohydrolase II [Coenzyme metabolism]; Region: RibA; COG0807
1055528002177	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055528002178	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1055528002179	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1055528002180	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
1055528002181	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
1055528002182	RNA methyltransferase, RsmD family; Region: TIGR00095
1055528002183	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1055528002184	Uncharacterized conserved protein [Function unknown]; Region: COG1565
1055528002185	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1055528002186	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
1055528002187	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1055528002188	ATP binding site [chemical binding]; other site
1055528002189	substrate interface [chemical binding]; other site
1055528002190	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1055528002191	flagellar motor protein MotA; Validated; Region: PRK08456
1055528002192	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
1055528002193	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1055528002194	ligand binding site [chemical binding]; other site
1055528002195	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528002196	dimer interface [polypeptide binding]; other site
1055528002197	conserved gate region; other site
1055528002198	ABC-ATPase subunit interface; other site
1055528002199	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1055528002200	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1055528002201	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528002202	Walker A/P-loop; other site
1055528002203	ATP binding site [chemical binding]; other site
1055528002204	Q-loop/lid; other site
1055528002205	ABC transporter signature motif; other site
1055528002206	Walker B; other site
1055528002207	D-loop; other site
1055528002208	H-loop/switch region; other site
1055528002209	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
1055528002210	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1055528002211	GIY-YIG motif/motif A; other site
1055528002212	active site
1055528002213	catalytic site [active]
1055528002214	putative DNA binding site [nucleotide binding]; other site
1055528002215	metal binding site [ion binding]; metal-binding site
1055528002216	UvrB/uvrC motif; Region: UVR; pfam02151
1055528002217	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1055528002218	homoserine dehydrogenase; Provisional; Region: PRK06349
1055528002219	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1055528002220	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1055528002221	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
1055528002222	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1055528002223	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1055528002224	catalytic residues [active]
1055528002225	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1055528002226	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1055528002227	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1055528002228	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1055528002229	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
1055528002230	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
1055528002231	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1055528002232	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1055528002233	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1055528002234	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1055528002235	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1055528002236	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1055528002237	active site
1055528002238	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Region: gatA; TIGR00132
1055528002239	indole acetimide hydrolase; Validated; Region: PRK07488
1055528002240	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1055528002241	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1055528002242	CoA-binding site [chemical binding]; other site
1055528002243	spermidine synthase; Provisional; Region: speE; PRK00536
1055528002244	spermidine synthase; Provisional; Region: PRK00811
1055528002245	GTP-binding protein Der; Reviewed; Region: PRK00093
1055528002246	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1055528002247	G1 box; other site
1055528002248	GTP/Mg2+ binding site [chemical binding]; other site
1055528002249	Switch I region; other site
1055528002250	G2 box; other site
1055528002251	Switch II region; other site
1055528002252	G3 box; other site
1055528002253	G4 box; other site
1055528002254	G5 box; other site
1055528002255	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1055528002256	G1 box; other site
1055528002257	GTP/Mg2+ binding site [chemical binding]; other site
1055528002258	Switch I region; other site
1055528002259	G2 box; other site
1055528002260	G3 box; other site
1055528002261	Switch II region; other site
1055528002262	G4 box; other site
1055528002263	G5 box; other site
1055528002264	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1055528002265	IHF dimer interface [polypeptide binding]; other site
1055528002266	IHF - DNA interface [nucleotide binding]; other site
1055528002267	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
1055528002268	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
1055528002269	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
1055528002270	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
1055528002271	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1055528002272	NAD(P) binding site [chemical binding]; other site
1055528002273	homodimer interface [polypeptide binding]; other site
1055528002274	substrate binding site [chemical binding]; other site
1055528002275	active site
1055528002276	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
1055528002277	Flavoprotein; Region: Flavoprotein; pfam02441
1055528002278	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1055528002279	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
1055528002280	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1055528002281	ligand binding site; other site
1055528002282	tetramer interface; other site
1055528002283	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1055528002284	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1055528002285	homodimer interface [polypeptide binding]; other site
1055528002286	active site
1055528002287	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1055528002288	NeuB family; Region: NeuB; pfam03102
1055528002289	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1055528002290	NeuB binding interface [polypeptide binding]; other site
1055528002291	putative substrate binding site [chemical binding]; other site
1055528002292	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1055528002293	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1055528002294	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528002295	ATP binding site [chemical binding]; other site
1055528002296	putative Mg++ binding site [ion binding]; other site
1055528002297	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1055528002298	thiamine phosphate binding site [chemical binding]; other site
1055528002299	active site
1055528002300	pyrophosphate binding site [ion binding]; other site
1055528002301	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1055528002302	ATP binding site [chemical binding]; other site
1055528002303	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1055528002304	substrate binding site [chemical binding]; other site
1055528002305	multimerization interface [polypeptide binding]; other site
1055528002306	ATP binding site [chemical binding]; other site
1055528002307	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1055528002308	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1055528002309	active site
1055528002310	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2958
1055528002311	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1055528002312	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528002313	Walker A/P-loop; other site
1055528002314	ATP binding site [chemical binding]; other site
1055528002315	Q-loop/lid; other site
1055528002316	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1055528002317	ABC transporter; Region: ABC_tran_2; pfam12848
1055528002318	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1055528002319	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
1055528002320	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1055528002321	active site
1055528002322	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1055528002323	dimer interface [polypeptide binding]; other site
1055528002324	active site
1055528002325	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
1055528002326	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1055528002327	putative ribose interaction site [chemical binding]; other site
1055528002328	putative ADP binding site [chemical binding]; other site
1055528002329	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1055528002330	active site
1055528002331	nucleotide binding site [chemical binding]; other site
1055528002332	HIGH motif; other site
1055528002333	KMSKS motif; other site
1055528002334	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1055528002335	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
1055528002336	NAD(P) binding site [chemical binding]; other site
1055528002337	active site
1055528002338	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1055528002339	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055528002340	active site
1055528002341	motif I; other site
1055528002342	motif II; other site
1055528002343	Uncharacterized conserved protein [Function unknown]; Region: COG2836
1055528002344	pantothenate kinase; Reviewed; Region: PRK13333
1055528002345	PQQ-like domain; Region: PQQ_2; pfam13360
1055528002346	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1055528002347	trimer interface [polypeptide binding]; other site
1055528002348	active site
1055528002349	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1055528002350	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1055528002351	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1055528002352	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1055528002353	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
1055528002354	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
1055528002355	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
1055528002356	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
1055528002357	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1055528002358	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1055528002359	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1055528002360	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055528002361	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1055528002362	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1055528002363	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1055528002364	PhnA protein; Region: PhnA; pfam03831
1055528002365	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1055528002366	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1055528002367	tetramer interface [polypeptide binding]; other site
1055528002368	heme binding pocket [chemical binding]; other site
1055528002369	NADPH binding site [chemical binding]; other site
1055528002370	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1055528002371	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055528002372	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055528002373	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1055528002374	active site
1055528002375	putative DNA-binding cleft [nucleotide binding]; other site
1055528002376	dimer interface [polypeptide binding]; other site
1055528002377	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1055528002378	LabA_like proteins; Region: LabA_like; cd06167
1055528002379	putative metal binding site [ion binding]; other site
1055528002380	NPH3 family; Region: NPH3; pfam03000
1055528002381	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
1055528002382	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
1055528002383	RuvA N terminal domain; Region: RuvA_N; pfam01330
1055528002384	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1055528002385	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1055528002386	MviN-like protein; Region: MVIN; pfam03023
1055528002387	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1055528002388	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1055528002389	active site
1055528002390	HIGH motif; other site
1055528002391	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1055528002392	KMSKS motif; other site
1055528002393	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1055528002394	tRNA binding surface [nucleotide binding]; other site
1055528002395	anticodon binding site; other site
1055528002396	Vacuolating cyotoxin; Region: VacA; pfam02691
1055528002397	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1055528002398	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055528002399	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1055528002400	Ligand binding site; other site
1055528002401	metal-binding site
1055528002402	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1055528002403	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1055528002404	Walker A/P-loop; other site
1055528002405	ATP binding site [chemical binding]; other site
1055528002406	Q-loop/lid; other site
1055528002407	ABC transporter signature motif; other site
1055528002408	Walker B; other site
1055528002409	D-loop; other site
1055528002410	H-loop/switch region; other site
1055528002411	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1055528002412	ABC-ATPase subunit  interface; other site
1055528002413	dimer interface [polypeptide binding]; other site
1055528002414	putative PBP binding regions; other site
1055528002415	short chain dehydrogenase; Validated; Region: PRK06182
1055528002416	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1055528002417	NADP binding site [chemical binding]; other site
1055528002418	active site
1055528002419	steroid binding site; other site
1055528002420	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1055528002421	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1055528002422	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002423	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1055528002424	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1055528002425	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
1055528002426	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
1055528002427	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1055528002428	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1055528002429	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1055528002430	propionate/acetate kinase; Provisional; Region: PRK12379
1055528002431	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
1055528002432	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1055528002433	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1055528002434	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
1055528002435	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1055528002436	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1055528002437	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
1055528002438	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055528002439	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1055528002440	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528002441	S-adenosylmethionine binding site [chemical binding]; other site
1055528002442	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1055528002443	Part of AAA domain; Region: AAA_19; pfam13245
1055528002444	Family description; Region: UvrD_C_2; pfam13538
1055528002445	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002446	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002447	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528002448	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1055528002449	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055528002450	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055528002451	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1055528002452	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1055528002453	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1055528002454	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1055528002455	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1055528002456	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1055528002457	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1055528002458	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1055528002459	IMP binding site; other site
1055528002460	dimer interface [polypeptide binding]; other site
1055528002461	interdomain contacts; other site
1055528002462	partial ornithine binding site; other site
1055528002463	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1055528002464	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1055528002465	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1055528002466	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1055528002467	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1055528002468	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055528002469	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
1055528002470	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
1055528002471	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1055528002472	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002473	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
1055528002474	active site 1 [active]
1055528002475	dimer interface [polypeptide binding]; other site
1055528002476	hexamer interface [polypeptide binding]; other site
1055528002477	active site 2 [active]
1055528002478	recombination protein RecR; Region: recR; TIGR00615
1055528002479	RecR protein; Region: RecR; pfam02132
1055528002480	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1055528002481	putative active site [active]
1055528002482	putative metal-binding site [ion binding]; other site
1055528002483	tetramer interface [polypeptide binding]; other site
1055528002484	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
1055528002485	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1055528002486	Permutation of conserved domain; other site
1055528002487	active site
1055528002488	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1055528002489	heat shock protein HtpX; Provisional; Region: PRK02870
1055528002490	GTP cyclohydrolase I; Region: folE; TIGR00063
1055528002491	GTP cyclohydrolase I; Provisional; Region: PLN03044
1055528002492	active site
1055528002493	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1055528002494	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1055528002495	substrate binding pocket [chemical binding]; other site
1055528002496	chain length determination region; other site
1055528002497	substrate-Mg2+ binding site; other site
1055528002498	catalytic residues [active]
1055528002499	aspartate-rich region 1; other site
1055528002500	active site lid residues [active]
1055528002501	aspartate-rich region 2; other site
1055528002502	Predicted acid phosphatase [General function prediction only]; Region: SurE; COG0496
1055528002503	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
1055528002504	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1055528002505	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1055528002506	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1055528002507	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1055528002508	Coenzyme A binding pocket [chemical binding]; other site
1055528002509	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1055528002510	potential frameshift: common BLAST hit: gi|188527758|ref|YP_001910445.1| putative outer membrane protein HomB
1055528002511	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055528002512	putative substrate translocation pore; other site
1055528002513	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1055528002514	Protein of unknown function DUF262; Region: DUF262; pfam03235
1055528002515	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1055528002516	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528002517	dimer interface [polypeptide binding]; other site
1055528002518	conserved gate region; other site
1055528002519	putative PBP binding loops; other site
1055528002520	ABC-ATPase subunit interface; other site
1055528002521	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1055528002522	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1055528002523	substrate binding pocket [chemical binding]; other site
1055528002524	membrane-bound complex binding site; other site
1055528002525	hinge residues; other site
1055528002526	alanine racemase; Region: alr; TIGR00492
1055528002527	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1055528002528	active site
1055528002529	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055528002530	dimer interface [polypeptide binding]; other site
1055528002531	substrate binding site [chemical binding]; other site
1055528002532	catalytic residues [active]
1055528002533	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1055528002534	amino acid carrier protein; Region: agcS; TIGR00835
1055528002535	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1055528002536	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
1055528002537	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1055528002538	homotrimer interaction site [polypeptide binding]; other site
1055528002539	putative active site [active]
1055528002540	TRL-like protein family; Region: TRL; pfam13146
1055528002541	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1055528002542	Uncharacterized conserved protein [Function unknown]; Region: COG1576
1055528002543	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
1055528002544	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1055528002545	putative recombination protein RecO; Provisional; Region: PRK13908
1055528002546	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
1055528002547	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1055528002548	dimer interface [polypeptide binding]; other site
1055528002549	FMN binding site [chemical binding]; other site
1055528002550	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
1055528002551	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1055528002552	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1055528002553	active site
1055528002554	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1055528002555	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1055528002556	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1055528002557	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1055528002558	Putative zinc ribbon domain; Region: DUF164; pfam02591
1055528002559	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
1055528002560	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1055528002561	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1055528002562	dimer interface [polypeptide binding]; other site
1055528002563	motif 1; other site
1055528002564	active site
1055528002565	motif 2; other site
1055528002566	motif 3; other site
1055528002567	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1055528002568	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1055528002569	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1055528002570	acyl carrier protein; Provisional; Region: acpP; PRK00982
1055528002571	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1055528002572	Dynamin family; Region: Dynamin_N; pfam00350
1055528002573	G1 box; other site
1055528002574	GTP/Mg2+ binding site [chemical binding]; other site
1055528002575	G2 box; other site
1055528002576	Switch I region; other site
1055528002577	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1055528002578	G3 box; other site
1055528002579	Switch II region; other site
1055528002580	G4 box; other site
1055528002581	Uncharacterized virulence-associated protein D [Function unknown]; Region: VapD; COG3309
1055528002582	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
1055528002583	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1055528002584	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1055528002585	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055528002586	Outer membrane efflux protein; Region: OEP; pfam02321
1055528002587	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
1055528002588	phosphoglyceromutase; Provisional; Region: PRK05434
1055528002589	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1055528002590	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
1055528002591	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
1055528002592	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1055528002593	inhibitor-cofactor binding pocket; inhibition site
1055528002594	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528002595	catalytic residue [active]
1055528002596	SurA N-terminal domain; Region: SurA_N_3; cl07813
1055528002597	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1055528002598	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1055528002599	cell division protein FtsA; Region: ftsA; TIGR01174
1055528002600	Cell division protein FtsA; Region: FtsA; smart00842
1055528002601	Cell division protein FtsA; Region: FtsA; pfam14450
1055528002602	cell division protein FtsZ; Validated; Region: PRK09330
1055528002603	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1055528002604	nucleotide binding site [chemical binding]; other site
1055528002605	SulA interaction site; other site
1055528002606	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1055528002607	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1055528002608	potential frameshift: common BLAST hit: gi|308183132|ref|YP_003927259.1| mechanosensitive channel MscS
1055528002609	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1055528002610	generic binding surface II; other site
1055528002611	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1055528002612	active site
1055528002613	Domain of unknown function (DUF1887); Region: DUF1887; pfam09002
1055528002614	AAA domain; Region: AAA_33; pfam13671
1055528002615	GTPase subunit of restriction endonuclease [Defense mechanisms]; Region: McrB; COG1401
1055528002616	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528002617	Walker A motif; other site
1055528002618	ATP binding site [chemical binding]; other site
1055528002619	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
1055528002620	AAA domain; Region: AAA_11; pfam13086
1055528002621	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1055528002622	AAA domain; Region: AAA_30; pfam13604
1055528002623	AAA domain; Region: AAA_12; pfam13087
1055528002624	Protein kinase domain; Region: Pkinase; pfam00069
1055528002625	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1055528002626	active site
1055528002627	ATP binding site [chemical binding]; other site
1055528002628	substrate binding site [chemical binding]; other site
1055528002629	activation loop (A-loop); other site
1055528002630	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1055528002631	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1055528002632	active site
1055528002633	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1055528002634	metal ion-dependent adhesion site (MIDAS); other site
1055528002635	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
1055528002636	Fic family protein [Function unknown]; Region: COG3177
1055528002637	Fic/DOC family; Region: Fic; pfam02661
1055528002638	potential frameshift: common BLAST hit: gi|308185145|ref|YP_003929278.1| integrase/recombinase (xerD)
1055528002639	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1055528002640	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1055528002641	active site
1055528002642	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055528002643	catalytic residues [active]
1055528002644	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1055528002645	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1055528002646	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
1055528002647	putative ADP-binding pocket [chemical binding]; other site
1055528002648	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1055528002649	active site 2 [active]
1055528002650	active site 1 [active]
1055528002651	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1055528002652	potential frameshift: common BLAST hit: gi|308183143|ref|YP_003927270.1| methionyl-tRNA synthetase
1055528002653	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
1055528002654	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528002655	S-adenosylmethionine binding site [chemical binding]; other site
1055528002656	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1055528002657	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1055528002658	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
1055528002659	GMP synthase; Reviewed; Region: guaA; PRK00074
1055528002660	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1055528002661	AMP/PPi binding site [chemical binding]; other site
1055528002662	candidate oxyanion hole; other site
1055528002663	catalytic triad [active]
1055528002664	potential glutamine specificity residues [chemical binding]; other site
1055528002665	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1055528002666	ATP Binding subdomain [chemical binding]; other site
1055528002667	Ligand Binding sites [chemical binding]; other site
1055528002668	Dimerization subdomain; other site
1055528002669	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1055528002670	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1055528002671	molybdopterin cofactor binding site [chemical binding]; other site
1055528002672	substrate binding site [chemical binding]; other site
1055528002673	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1055528002674	molybdopterin cofactor binding site; other site
1055528002675	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
1055528002676	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1055528002677	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1055528002678	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1055528002679	catalytic residue [active]
1055528002680	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1055528002681	nucleotide binding site/active site [active]
1055528002682	HIT family signature motif; other site
1055528002683	catalytic residue [active]
1055528002684	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1055528002685	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1055528002686	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1055528002687	dimer interface [polypeptide binding]; other site
1055528002688	motif 1; other site
1055528002689	active site
1055528002690	motif 2; other site
1055528002691	motif 3; other site
1055528002692	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1055528002693	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1055528002694	putative tRNA-binding site [nucleotide binding]; other site
1055528002695	tRNA synthetase B5 domain; Region: B5; pfam03484
1055528002696	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1055528002697	dimer interface [polypeptide binding]; other site
1055528002698	motif 1; other site
1055528002699	motif 3; other site
1055528002700	motif 2; other site
1055528002701	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1055528002702	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1055528002703	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1055528002704	hinge; other site
1055528002705	active site
1055528002706	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1055528002707	LytB protein; Region: LYTB; pfam02401
1055528002708	ribosomal protein S1; Region: rpsA; TIGR00717
1055528002709	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1055528002710	RNA binding site [nucleotide binding]; other site
1055528002711	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1055528002712	RNA binding site [nucleotide binding]; other site
1055528002713	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1055528002714	RNA binding site [nucleotide binding]; other site
1055528002715	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1055528002716	RNA binding site [nucleotide binding]; other site
1055528002717	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
1055528002718	RNA binding site [nucleotide binding]; other site
1055528002719	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
1055528002720	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1055528002721	ligand binding site [chemical binding]; other site
1055528002722	NAD binding site [chemical binding]; other site
1055528002723	dimerization interface [polypeptide binding]; other site
1055528002724	catalytic site [active]
1055528002725	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
1055528002726	putative L-serine binding site [chemical binding]; other site
1055528002727	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
1055528002728	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
1055528002729	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1055528002730	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1055528002731	catalytic residue [active]
1055528002732	potential frameshift: common BLAST hit: gi|308183163|ref|YP_003927290.1| UDP-2,3-diacylglucosamine hydrolase
1055528002733	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1055528002734	putative CheA interaction surface; other site
1055528002735	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1055528002736	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528002737	active site
1055528002738	phosphorylation site [posttranslational modification]
1055528002739	intermolecular recognition site; other site
1055528002740	dimerization interface [polypeptide binding]; other site
1055528002741	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1055528002742	putative binding surface; other site
1055528002743	active site
1055528002744	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1055528002745	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1055528002746	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055528002747	ATP binding site [chemical binding]; other site
1055528002748	Mg2+ binding site [ion binding]; other site
1055528002749	G-X-G motif; other site
1055528002750	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1055528002751	Response regulator receiver domain; Region: Response_reg; pfam00072
1055528002752	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528002753	active site
1055528002754	phosphorylation site [posttranslational modification]
1055528002755	intermolecular recognition site; other site
1055528002756	dimerization interface [polypeptide binding]; other site
1055528002757	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1055528002758	putative CheA interaction surface; other site
1055528002759	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1055528002760	dimer interface [polypeptide binding]; other site
1055528002761	catalytic triad [active]
1055528002762	peroxidatic and resolving cysteines [active]
1055528002763	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1055528002764	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1055528002765	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1055528002766	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1055528002767	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528002768	S-adenosylmethionine binding site [chemical binding]; other site
1055528002769	potential frameshift: common BLAST hit: gi|188527848|ref|YP_001910535.1| primosome assembly protein PriA
1055528002770	Sporulation related domain; Region: SPOR; pfam05036
1055528002771	Peptidase family M48; Region: Peptidase_M48; pfam01435
1055528002772	HemK family putative methylases; Region: hemK_fam; TIGR00536
1055528002773	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1055528002774	glutamate dehydrogenase; Provisional; Region: PRK09414
1055528002775	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1055528002776	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1055528002777	NAD(P) binding site [chemical binding]; other site
1055528002778	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
1055528002779	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
1055528002780	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
1055528002781	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
1055528002782	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1055528002783	catalytic residues [active]
1055528002784	ferrochelatase; Region: hemH; TIGR00109
1055528002785	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1055528002786	C-terminal domain interface [polypeptide binding]; other site
1055528002787	active site
1055528002788	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1055528002789	active site
1055528002790	N-terminal domain interface [polypeptide binding]; other site
1055528002791	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1055528002792	RNA methyltransferase, RsmE family; Region: TIGR00046
1055528002793	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002794	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1055528002795	trimer interface [polypeptide binding]; other site
1055528002796	active site
1055528002797	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
1055528002798	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1055528002799	carboxyltransferase (CT) interaction site; other site
1055528002800	biotinylation site [posttranslational modification]; other site
1055528002801	biotin carboxylase; Validated; Region: PRK08462
1055528002802	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1055528002803	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1055528002804	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1055528002805	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055528002806	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1055528002807	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1055528002808	inhibitor-cofactor binding pocket; inhibition site
1055528002809	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528002810	catalytic residue [active]
1055528002811	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1055528002812	dimer interface [polypeptide binding]; other site
1055528002813	putative radical transfer pathway; other site
1055528002814	diiron center [ion binding]; other site
1055528002815	tyrosyl radical; other site
1055528002816	protein-L-isoaspartate(D-aspartate) O-methyltransferase; Region: pimt; TIGR00080
1055528002817	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528002818	S-adenosylmethionine binding site [chemical binding]; other site
1055528002819	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1055528002820	Predicted permeases [General function prediction only]; Region: COG0795
1055528002821	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
1055528002822	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1055528002823	dimerization interface 3.5A [polypeptide binding]; other site
1055528002824	active site
1055528002825	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
1055528002826	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1055528002827	NAD binding site [chemical binding]; other site
1055528002828	homodimer interface [polypeptide binding]; other site
1055528002829	active site
1055528002830	substrate binding site [chemical binding]; other site
1055528002831	potential protein location (hypothetical protein HPPN120_05300 [Helicobacter pylori Puno120]) that overlaps RNA (tRNA-I)
1055528002832	potential protein location (hypothetical protein HPPN120_05305 [Helicobacter pylori Puno120]) that overlaps RNA (tRNA-A)
1055528002833	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1055528002834	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1055528002835	putative NAD(P) binding site [chemical binding]; other site
1055528002836	homodimer interface [polypeptide binding]; other site
1055528002837	homotetramer interface [polypeptide binding]; other site
1055528002838	active site
1055528002839	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528002840	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055528002841	binding surface
1055528002842	TPR motif; other site
1055528002843	Sel1-like repeats; Region: SEL1; smart00671
1055528002844	Sel1-like repeats; Region: SEL1; smart00671
1055528002845	Sel1-like repeats; Region: SEL1; smart00671
1055528002846	Entner-Doudoroff aldolase; Region: eda; TIGR01182
1055528002847	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1055528002848	active site
1055528002849	intersubunit interface [polypeptide binding]; other site
1055528002850	catalytic residue [active]
1055528002851	phosphogluconate dehydratase; Validated; Region: PRK09054
1055528002852	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1055528002853	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
1055528002854	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1055528002855	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1055528002856	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1055528002857	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
1055528002858	putative active site [active]
1055528002859	glucokinase, proteobacterial type; Region: glk; TIGR00749
1055528002860	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1055528002861	nucleotide binding site [chemical binding]; other site
1055528002862	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1055528002863	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1055528002864	putative NAD(P) binding site [chemical binding]; other site
1055528002865	putative substrate binding site [chemical binding]; other site
1055528002866	catalytic Zn binding site [ion binding]; other site
1055528002867	structural Zn binding site [ion binding]; other site
1055528002868	dimer interface [polypeptide binding]; other site
1055528002869	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055528002870	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055528002871	active site
1055528002872	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055528002873	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1055528002874	active site
1055528002875	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002876	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
1055528002877	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
1055528002878	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
1055528002879	4Fe-4S binding domain; Region: Fer4; pfam00037
1055528002880	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
1055528002881	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1055528002882	dimer interface [polypeptide binding]; other site
1055528002883	PYR/PP interface [polypeptide binding]; other site
1055528002884	TPP binding site [chemical binding]; other site
1055528002885	substrate binding site [chemical binding]; other site
1055528002886	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1055528002887	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
1055528002888	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
1055528002889	TPP-binding site [chemical binding]; other site
1055528002890	putative dimer interface [polypeptide binding]; other site
1055528002891	adenylosuccinate lyase; Provisional; Region: PRK08470
1055528002892	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1055528002893	tetramer interface [polypeptide binding]; other site
1055528002894	active site
1055528002895	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1055528002896	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528002897	excinuclease ABC subunit B; Provisional; Region: PRK05298
1055528002898	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528002899	ATP binding site [chemical binding]; other site
1055528002900	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1055528002901	putative Mg++ binding site [ion binding]; other site
1055528002902	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055528002903	nucleotide binding region [chemical binding]; other site
1055528002904	ATP-binding site [chemical binding]; other site
1055528002905	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1055528002906	UvrB/uvrC motif; Region: UVR; pfam02151
1055528002907	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1055528002908	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055528002909	binding surface
1055528002910	TPR motif; other site
1055528002911	Sel1-like repeats; Region: SEL1; smart00671
1055528002912	Sel1-like repeats; Region: SEL1; smart00671
1055528002913	Sel1 repeat; Region: Sel1; cl02723
1055528002914	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1055528002915	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1055528002916	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
1055528002917	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055528002918	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055528002919	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
1055528002920	cofactor binding site; other site
1055528002921	DNA binding site [nucleotide binding]
1055528002922	substrate interaction site [chemical binding]; other site
1055528002923	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1055528002924	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
1055528002925	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1055528002926	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1055528002927	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1055528002928	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1055528002929	ligand binding site [chemical binding]; other site
1055528002930	translocation protein TolB; Provisional; Region: tolB; PRK04043
1055528002931	TolB amino-terminal domain; Region: TolB_N; pfam04052
1055528002932	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1055528002933	TonB C terminal; Region: TonB_2; pfam13103
1055528002934	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1055528002935	TolR protein; Region: tolR; TIGR02801
1055528002936	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
1055528002937	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
1055528002938	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1055528002939	gamma subunit interface [polypeptide binding]; other site
1055528002940	epsilon subunit interface [polypeptide binding]; other site
1055528002941	LBP interface [polypeptide binding]; other site
1055528002942	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1055528002943	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1055528002944	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1055528002945	alpha subunit interaction interface [polypeptide binding]; other site
1055528002946	Walker A motif; other site
1055528002947	ATP binding site [chemical binding]; other site
1055528002948	Walker B motif; other site
1055528002949	inhibitor binding site; inhibition site
1055528002950	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1055528002951	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1055528002952	core domain interface [polypeptide binding]; other site
1055528002953	delta subunit interface [polypeptide binding]; other site
1055528002954	epsilon subunit interface [polypeptide binding]; other site
1055528002955	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1055528002956	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1055528002957	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1055528002958	beta subunit interaction interface [polypeptide binding]; other site
1055528002959	Walker A motif; other site
1055528002960	ATP binding site [chemical binding]; other site
1055528002961	Walker B motif; other site
1055528002962	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1055528002963	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
1055528002964	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
1055528002965	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
1055528002966	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1055528002967	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1055528002968	ParB-like nuclease domain; Region: ParB; smart00470
1055528002969	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1055528002970	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1055528002971	P-loop; other site
1055528002972	Magnesium ion binding site [ion binding]; other site
1055528002973	biotin--protein ligase; Provisional; Region: PRK08477
1055528002974	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1055528002975	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1055528002976	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1055528002977	putative active site [active]
1055528002978	substrate binding site [chemical binding]; other site
1055528002979	putative cosubstrate binding site; other site
1055528002980	catalytic site [active]
1055528002981	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1055528002982	substrate binding site [chemical binding]; other site
1055528002983	PHP-associated; Region: PHP_C; pfam13263
1055528002984	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528002985	Walker A/P-loop; other site
1055528002986	ATP binding site [chemical binding]; other site
1055528002987	AAA domain; Region: AAA_21; pfam13304
1055528002988	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1055528002989	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1055528002990	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1055528002991	LabA_like proteins; Region: LabA_like; cd06167
1055528002992	putative metal binding site [ion binding]; other site
1055528002993	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1055528002994	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
1055528002995	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
1055528002996	RimM N-terminal domain; Region: RimM; pfam01782
1055528002997	PRC-barrel domain; Region: PRC; pfam05239
1055528002998	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1055528002999	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cd02409
1055528003000	G-X-X-G motif; other site
1055528003001	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1055528003002	signal recognition particle protein; Provisional; Region: PRK10867
1055528003003	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1055528003004	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1055528003005	P loop; other site
1055528003006	GTP binding site [chemical binding]; other site
1055528003007	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1055528003008	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1055528003009	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1055528003010	active site
1055528003011	HIGH motif; other site
1055528003012	nucleotide binding site [chemical binding]; other site
1055528003013	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1055528003014	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1055528003015	active site
1055528003016	KMSKS motif; other site
1055528003017	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1055528003018	anticodon binding site; other site
1055528003019	flagellar assembly protein FliW; Provisional; Region: PRK13283
1055528003020	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
1055528003021	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1055528003022	active site
1055528003023	homodimer interface [polypeptide binding]; other site
1055528003024	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003025	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003026	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1055528003027	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1055528003028	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1055528003029	Fic/DOC family; Region: Fic; cl00960
1055528003030	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
1055528003031	active site
1055528003032	iron coordination sites [ion binding]; other site
1055528003033	substrate binding pocket [chemical binding]; other site
1055528003034	Uncharacterized conserved protein [Function unknown]; Region: COG4278
1055528003035	metal-binding heat shock protein; Provisional; Region: PRK00016
1055528003036	flavodoxin FldA; Validated; Region: PRK09267
1055528003037	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1055528003038	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1055528003039	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
1055528003040	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1055528003041	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1055528003042	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1055528003043	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1055528003044	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1055528003045	active site
1055528003046	dimer interface [polypeptide binding]; other site
1055528003047	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1055528003048	dimer interface [polypeptide binding]; other site
1055528003049	active site
1055528003050	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
1055528003051	carbon starvation protein A; Provisional; Region: PRK15015
1055528003052	Carbon starvation protein CstA; Region: CstA; pfam02554
1055528003053	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1055528003054	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1055528003055	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528003056	dimer interface [polypeptide binding]; other site
1055528003057	conserved gate region; other site
1055528003058	putative PBP binding loops; other site
1055528003059	ABC-ATPase subunit interface; other site
1055528003060	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528003061	dimer interface [polypeptide binding]; other site
1055528003062	conserved gate region; other site
1055528003063	putative PBP binding loops; other site
1055528003064	ABC-ATPase subunit interface; other site
1055528003065	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1055528003066	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1055528003067	Walker A/P-loop; other site
1055528003068	ATP binding site [chemical binding]; other site
1055528003069	Q-loop/lid; other site
1055528003070	ABC transporter signature motif; other site
1055528003071	Walker B; other site
1055528003072	D-loop; other site
1055528003073	H-loop/switch region; other site
1055528003074	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1055528003075	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1055528003076	substrate binding pocket [chemical binding]; other site
1055528003077	membrane-bound complex binding site; other site
1055528003078	hinge residues; other site
1055528003079	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1055528003080	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055528003081	putative substrate translocation pore; other site
1055528003082	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1055528003083	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003084	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
1055528003085	phosphopentomutase; Provisional; Region: PRK05362
1055528003086	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1055528003087	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1055528003088	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1055528003089	Nucleoside recognition; Region: Gate; pfam07670
1055528003090	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1055528003091	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055528003092	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1055528003093	putative substrate translocation pore; other site
1055528003094	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1055528003095	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1055528003096	Ligand Binding Site [chemical binding]; other site
1055528003097	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1055528003098	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1055528003099	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1055528003100	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1055528003101	putative arabinose transporter; Provisional; Region: PRK03545
1055528003102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1055528003103	putative substrate translocation pore; other site
1055528003104	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
1055528003105	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1055528003106	active site
1055528003107	zinc binding site [ion binding]; other site
1055528003108	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
1055528003109	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1055528003110	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
1055528003111	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1055528003112	dimer interface [polypeptide binding]; other site
1055528003113	motif 1; other site
1055528003114	active site
1055528003115	motif 2; other site
1055528003116	motif 3; other site
1055528003117	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1055528003118	anticodon binding site; other site
1055528003119	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055528003120	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055528003121	putative active site [active]
1055528003122	elongation factor G; Reviewed; Region: PRK00007
1055528003123	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1055528003124	G1 box; other site
1055528003125	putative GEF interaction site [polypeptide binding]; other site
1055528003126	GTP/Mg2+ binding site [chemical binding]; other site
1055528003127	Switch I region; other site
1055528003128	G2 box; other site
1055528003129	G3 box; other site
1055528003130	Switch II region; other site
1055528003131	G4 box; other site
1055528003132	G5 box; other site
1055528003133	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1055528003134	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1055528003135	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1055528003136	30S ribosomal protein S7; Validated; Region: PRK05302
1055528003137	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1055528003138	S17 interaction site [polypeptide binding]; other site
1055528003139	S8 interaction site; other site
1055528003140	16S rRNA interaction site [nucleotide binding]; other site
1055528003141	streptomycin interaction site [chemical binding]; other site
1055528003142	23S rRNA interaction site [nucleotide binding]; other site
1055528003143	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1055528003144	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
1055528003145	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1055528003146	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1055528003147	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1055528003148	RPB11 interaction site [polypeptide binding]; other site
1055528003149	RPB12 interaction site [polypeptide binding]; other site
1055528003150	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1055528003151	RPB3 interaction site [polypeptide binding]; other site
1055528003152	RPB1 interaction site [polypeptide binding]; other site
1055528003153	RPB11 interaction site [polypeptide binding]; other site
1055528003154	RPB10 interaction site [polypeptide binding]; other site
1055528003155	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1055528003156	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1055528003157	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1055528003158	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1055528003159	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1055528003160	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1055528003161	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1055528003162	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1055528003163	DNA binding site [nucleotide binding]
1055528003164	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1055528003165	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1055528003166	core dimer interface [polypeptide binding]; other site
1055528003167	peripheral dimer interface [polypeptide binding]; other site
1055528003168	L10 interface [polypeptide binding]; other site
1055528003169	L11 interface [polypeptide binding]; other site
1055528003170	putative EF-Tu interaction site [polypeptide binding]; other site
1055528003171	putative EF-G interaction site [polypeptide binding]; other site
1055528003172	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1055528003173	23S rRNA interface [nucleotide binding]; other site
1055528003174	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1055528003175	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1055528003176	mRNA/rRNA interface [nucleotide binding]; other site
1055528003177	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1055528003178	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1055528003179	23S rRNA interface [nucleotide binding]; other site
1055528003180	L7/L12 interface [polypeptide binding]; other site
1055528003181	putative thiostrepton binding site; other site
1055528003182	L25 interface [polypeptide binding]; other site
1055528003183	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1055528003184	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1055528003185	putative homodimer interface [polypeptide binding]; other site
1055528003186	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1055528003187	heterodimer interface [polypeptide binding]; other site
1055528003188	homodimer interface [polypeptide binding]; other site
1055528003189	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
1055528003190	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1055528003191	elongation factor Tu; Reviewed; Region: PRK00049
1055528003192	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1055528003193	G1 box; other site
1055528003194	GEF interaction site [polypeptide binding]; other site
1055528003195	GTP/Mg2+ binding site [chemical binding]; other site
1055528003196	Switch I region; other site
1055528003197	G2 box; other site
1055528003198	G3 box; other site
1055528003199	Switch II region; other site
1055528003200	G4 box; other site
1055528003201	G5 box; other site
1055528003202	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1055528003203	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1055528003204	Antibiotic Binding Site [chemical binding]; other site
1055528003205	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1055528003206	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528003207	Walker A/P-loop; other site
1055528003208	ATP binding site [chemical binding]; other site
1055528003209	Q-loop/lid; other site
1055528003210	ABC transporter signature motif; other site
1055528003211	Walker B; other site
1055528003212	D-loop; other site
1055528003213	H-loop/switch region; other site
1055528003214	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1055528003215	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1055528003216	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1055528003217	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
1055528003218	Helicobacter pylori IceA2 protein; Region: IceA2; pfam05862
1055528003219	serine O-acetyltransferase; Region: cysE; TIGR01172
1055528003220	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1055528003221	trimer interface [polypeptide binding]; other site
1055528003222	active site
1055528003223	substrate binding site [chemical binding]; other site
1055528003224	CoA binding site [chemical binding]; other site
1055528003225	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
1055528003226	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1055528003227	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1055528003228	oligomer interface [polypeptide binding]; other site
1055528003229	RNA binding site [nucleotide binding]; other site
1055528003230	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1055528003231	oligomer interface [polypeptide binding]; other site
1055528003232	RNA binding site [nucleotide binding]; other site
1055528003233	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1055528003234	putative nucleic acid binding region [nucleotide binding]; other site
1055528003235	G-X-X-G motif; other site
1055528003236	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1055528003237	RNA binding site [nucleotide binding]; other site
1055528003238	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
1055528003239	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1055528003240	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1055528003241	Predicted membrane protein/domain [Function unknown]; Region: COG1714
1055528003242	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
1055528003243	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1055528003244	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1055528003245	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1055528003246	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1055528003247	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1055528003248	Walker A/P-loop; other site
1055528003249	ATP binding site [chemical binding]; other site
1055528003250	Q-loop/lid; other site
1055528003251	ABC transporter signature motif; other site
1055528003252	Walker B; other site
1055528003253	D-loop; other site
1055528003254	H-loop/switch region; other site
1055528003255	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1055528003256	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1055528003257	catalytic residue [active]
1055528003258	putative FPP diphosphate  binding site; other site
1055528003259	putative FPP binding hydrophobic cleft; other site
1055528003260	dimer interface [polypeptide binding]; other site
1055528003261	putative IPP diphosphate binding site; other site
1055528003262	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1055528003263	FAD binding domain; Region: FAD_binding_4; pfam01565
1055528003264	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1055528003265	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1055528003266	active site residue [active]
1055528003267	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1055528003268	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1055528003269	active site
1055528003270	camphor resistance protein CrcB; Provisional; Region: PRK14204
1055528003271	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
1055528003272	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528003273	FeS/SAM binding site; other site
1055528003274	HemN C-terminal domain; Region: HemN_C; pfam06969
1055528003275	Cytochrome c553 [Energy production and conversion]; Region: COG2863
1055528003276	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1055528003277	putative active site [active]
1055528003278	Ap4A binding site [chemical binding]; other site
1055528003279	nudix motif; other site
1055528003280	putative metal binding site [ion binding]; other site
1055528003281	aspartate kinase; Reviewed; Region: PRK06635
1055528003282	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1055528003283	putative nucleotide binding site [chemical binding]; other site
1055528003284	putative catalytic residues [active]
1055528003285	putative Mg ion binding site [ion binding]; other site
1055528003286	putative aspartate binding site [chemical binding]; other site
1055528003287	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1055528003288	putative allosteric regulatory site; other site
1055528003289	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1055528003290	putative allosteric regulatory residue; other site
1055528003291	DNA replication regulator; Region: HobA; pfam12163
1055528003292	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1055528003293	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1055528003294	dihydropteroate synthase; Region: DHPS; TIGR01496
1055528003295	substrate binding pocket [chemical binding]; other site
1055528003296	dimer interface [polypeptide binding]; other site
1055528003297	inhibitor binding site; inhibition site
1055528003298	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1055528003299	EamA-like transporter family; Region: EamA; pfam00892
1055528003300	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
1055528003301	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
1055528003302	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
1055528003303	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1055528003304	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1055528003305	catalytic site [active]
1055528003306	subunit interface [polypeptide binding]; other site
1055528003307	formamidase; Provisional; Region: amiF; PRK13287
1055528003308	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
1055528003309	multimer interface [polypeptide binding]; other site
1055528003310	active site
1055528003311	catalytic triad [active]
1055528003312	dimer interface [polypeptide binding]; other site
1055528003313	Maf-like protein; Reviewed; Region: PRK04056
1055528003314	putative active site [active]
1055528003315	potential frameshift: common BLAST hit: gi|188528029|ref|YP_001910716.1| alanyl-tRNA synthetase
1055528003316	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
1055528003317	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003318	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1055528003319	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1055528003320	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1055528003321	dimer interface [polypeptide binding]; other site
1055528003322	ssDNA binding site [nucleotide binding]; other site
1055528003323	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1055528003324	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1055528003325	DNA polymerase III subunit delta; Validated; Region: PRK08487
1055528003326	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1055528003327	Exoribonuclease R [Transcription]; Region: VacB; COG0557
1055528003328	RNB domain; Region: RNB; pfam00773
1055528003329	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
1055528003330	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1055528003331	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1055528003332	shikimate binding site; other site
1055528003333	NAD(P) binding site [chemical binding]; other site
1055528003334	Bacterial SH3 domain; Region: SH3_3; pfam08239
1055528003335	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1055528003336	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1055528003337	dimer interface [polypeptide binding]; other site
1055528003338	conserved gate region; other site
1055528003339	putative PBP binding loops; other site
1055528003340	ABC-ATPase subunit interface; other site
1055528003341	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1055528003342	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1055528003343	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1055528003344	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1055528003345	active site
1055528003346	HIGH motif; other site
1055528003347	dimer interface [polypeptide binding]; other site
1055528003348	KMSKS motif; other site
1055528003349	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1055528003350	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528003351	S-adenosylmethionine binding site [chemical binding]; other site
1055528003352	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1055528003353	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1055528003354	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1055528003355	hinge region; other site
1055528003356	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1055528003357	active site
1055528003358	RDD family; Region: RDD; pfam06271
1055528003359	NAD-dependent deacetylase; Provisional; Region: PRK00481
1055528003360	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1055528003361	NAD+ binding site [chemical binding]; other site
1055528003362	substrate binding site [chemical binding]; other site
1055528003363	Zn binding site [ion binding]; other site
1055528003364	NADH dehydrogenase subunit A; Validated; Region: PRK08489
1055528003365	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1055528003366	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
1055528003367	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1055528003368	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1055528003369	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
1055528003370	NADH dehydrogenase subunit G; Validated; Region: PRK08493
1055528003371	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1055528003372	catalytic loop [active]
1055528003373	iron binding site [ion binding]; other site
1055528003374	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1055528003375	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1055528003376	molybdopterin cofactor binding site; other site
1055528003377	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
1055528003378	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1055528003379	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1055528003380	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
1055528003381	4Fe-4S binding domain; Region: Fer4; cl02805
1055528003382	4Fe-4S binding domain; Region: Fer4; pfam00037
1055528003383	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
1055528003384	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1055528003385	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1055528003386	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1055528003387	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1055528003388	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1055528003389	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1055528003390	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1055528003391	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
1055528003392	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1055528003393	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
1055528003394	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1055528003395	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1055528003396	active site
1055528003397	substrate binding site [chemical binding]; other site
1055528003398	metal binding site [ion binding]; metal-binding site
1055528003399	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1055528003400	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1055528003401	substrate binding site [chemical binding]; other site
1055528003402	active site
1055528003403	catalytic residues [active]
1055528003404	heterodimer interface [polypeptide binding]; other site
1055528003405	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1055528003406	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1055528003407	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1055528003408	catalytic residue [active]
1055528003409	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1055528003410	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1055528003411	active site
1055528003412	ribulose/triose binding site [chemical binding]; other site
1055528003413	phosphate binding site [ion binding]; other site
1055528003414	substrate (anthranilate) binding pocket [chemical binding]; other site
1055528003415	product (indole) binding pocket [chemical binding]; other site
1055528003416	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1055528003417	active site
1055528003418	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1055528003419	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
1055528003420	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1055528003421	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1055528003422	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1055528003423	glutamine binding [chemical binding]; other site
1055528003424	catalytic triad [active]
1055528003425	anthranilate synthase component I, proteobacterial subset; Region: trpE_proteo; TIGR00565
1055528003426	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1055528003427	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1055528003428	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1055528003429	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1055528003430	putative active site [active]
1055528003431	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055528003432	active site
1055528003433	motif I; other site
1055528003434	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1055528003435	motif II; other site
1055528003436	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1055528003437	thiaminase II; Region: salvage_TenA; TIGR04306
1055528003438	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
1055528003439	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
1055528003440	Thiamine pyrophosphokinase; Region: TPK; cd07995
1055528003441	active site
1055528003442	dimerization interface [polypeptide binding]; other site
1055528003443	thiamine binding site [chemical binding]; other site
1055528003444	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1055528003445	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1055528003446	alphaNTD homodimer interface [polypeptide binding]; other site
1055528003447	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
1055528003448	alphaNTD - beta interaction site [polypeptide binding]; other site
1055528003449	alphaNTD - beta' interaction site [polypeptide binding]; other site
1055528003450	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1055528003451	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1055528003452	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1055528003453	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055528003454	RNA binding surface [nucleotide binding]; other site
1055528003455	30S ribosomal protein S11; Validated; Region: PRK05309
1055528003456	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1055528003457	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1055528003458	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
1055528003459	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1055528003460	rRNA binding site [nucleotide binding]; other site
1055528003461	predicted 30S ribosome binding site; other site
1055528003462	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1055528003463	active site
1055528003464	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1055528003465	SecY translocase; Region: SecY; pfam00344
1055528003466	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1055528003467	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
1055528003468	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1055528003469	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1055528003470	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1055528003471	23S rRNA interface [nucleotide binding]; other site
1055528003472	5S rRNA interface [nucleotide binding]; other site
1055528003473	L27 interface [polypeptide binding]; other site
1055528003474	L5 interface [polypeptide binding]; other site
1055528003475	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1055528003476	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1055528003477	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1055528003478	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1055528003479	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1055528003480	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1055528003481	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1055528003482	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1055528003483	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1055528003484	RNA binding site [nucleotide binding]; other site
1055528003485	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1055528003486	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1055528003487	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1055528003488	putative translocon interaction site; other site
1055528003489	23S rRNA interface [nucleotide binding]; other site
1055528003490	signal recognition particle (SRP54) interaction site; other site
1055528003491	L23 interface [polypeptide binding]; other site
1055528003492	trigger factor interaction site; other site
1055528003493	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1055528003494	23S rRNA interface [nucleotide binding]; other site
1055528003495	5S rRNA interface [nucleotide binding]; other site
1055528003496	putative antibiotic binding site [chemical binding]; other site
1055528003497	L25 interface [polypeptide binding]; other site
1055528003498	L27 interface [polypeptide binding]; other site
1055528003499	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1055528003500	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1055528003501	G-X-X-G motif; other site
1055528003502	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1055528003503	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1055528003504	putative translocon binding site; other site
1055528003505	protein-rRNA interface [nucleotide binding]; other site
1055528003506	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1055528003507	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1055528003508	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1055528003509	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1055528003510	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1055528003511	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1055528003512	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1055528003513	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1055528003514	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1055528003515	AAA domain; Region: AAA_14; pfam13173
1055528003516	Helix-turn-helix domain; Region: HTH_36; pfam13730
1055528003517	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1055528003518	RNA/DNA hybrid binding site [nucleotide binding]; other site
1055528003519	active site
1055528003520	SIR2-like domain; Region: SIR2_2; pfam13289
1055528003521	RecA-superfamily ATPases implicated in signal transduction [Signal transduction mechanisms]; Region: RAD55; COG0467
1055528003522	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1055528003523	Class II fumarases; Region: Fumarase_classII; cd01362
1055528003524	active site
1055528003525	tetramer interface [polypeptide binding]; other site
1055528003526	YtkA-like; Region: YtkA; pfam13115
1055528003527	Outer membrane efflux protein; Region: OEP; pfam02321
1055528003528	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1055528003529	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055528003530	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1055528003531	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
1055528003532	AzlC protein; Region: AzlC; cl00570
1055528003533	chaperone protein DnaJ; Provisional; Region: PRK14288
1055528003534	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1055528003535	HSP70 interaction site [polypeptide binding]; other site
1055528003536	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1055528003537	substrate binding site [polypeptide binding]; other site
1055528003538	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1055528003539	Zn binding sites [ion binding]; other site
1055528003540	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1055528003541	substrate binding site [polypeptide binding]; other site
1055528003542	dimer interface [polypeptide binding]; other site
1055528003543	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1055528003544	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1055528003545	Ligand Binding Site [chemical binding]; other site
1055528003546	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1055528003547	HSP70 interaction site [polypeptide binding]; other site
1055528003548	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1055528003549	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1055528003550	active site
1055528003551	(T/H)XGH motif; other site
1055528003552	nickel responsive regulator; Provisional; Region: PRK00630
1055528003553	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1055528003554	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1055528003555	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
1055528003556	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1055528003557	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1055528003558	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1055528003559	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1055528003560	potential frameshift: common BLAST hit: gi|15612326|ref|NP_223979.1| putative Outer membrane protein
1055528003561	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1055528003562	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1055528003563	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
1055528003564	Cl binding site [ion binding]; other site
1055528003565	oligomer interface [polypeptide binding]; other site
1055528003566	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
1055528003567	Phosphoglycerate kinase; Region: PGK; pfam00162
1055528003568	substrate binding site [chemical binding]; other site
1055528003569	hinge regions; other site
1055528003570	ADP binding site [chemical binding]; other site
1055528003571	catalytic site [active]
1055528003572	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1055528003573	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1055528003574	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1055528003575	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1055528003576	ligand binding site [chemical binding]; other site
1055528003577	active site
1055528003578	UGI interface [polypeptide binding]; other site
1055528003579	catalytic site [active]
1055528003580	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1055528003581	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1055528003582	putative acyl-acceptor binding pocket; other site
1055528003583	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1055528003584	C-terminal peptidase (prc); Region: prc; TIGR00225
1055528003585	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1055528003586	protein binding site [polypeptide binding]; other site
1055528003587	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1055528003588	Catalytic dyad [active]
1055528003589	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528003590	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528003591	Predicted helicase [General function prediction only]; Region: COG4889
1055528003592	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
1055528003593	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1055528003594	dimerization interface [polypeptide binding]; other site
1055528003595	active site
1055528003596	quinolinate synthetase complex, A subunit; Region: nadA; TIGR00550
1055528003597	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
1055528003598	prenyltransferase; Reviewed; Region: ubiA; PRK12874
1055528003599	UbiA prenyltransferase family; Region: UbiA; pfam01040
1055528003600	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1055528003601	Competence protein; Region: Competence; pfam03772
1055528003602	replicative DNA helicase; Provisional; Region: PRK08506
1055528003603	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1055528003604	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1055528003605	Walker A motif; other site
1055528003606	ATP binding site [chemical binding]; other site
1055528003607	Walker B motif; other site
1055528003608	DNA binding loops [nucleotide binding]
1055528003609	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
1055528003610	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1055528003611	putative substrate binding site [chemical binding]; other site
1055528003612	putative ATP binding site [chemical binding]; other site
1055528003613	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1055528003614	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1055528003615	dimer interface [polypeptide binding]; other site
1055528003616	phosphorylation site [posttranslational modification]
1055528003617	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1055528003618	ATP binding site [chemical binding]; other site
1055528003619	Mg2+ binding site [ion binding]; other site
1055528003620	G-X-G motif; other site
1055528003621	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1055528003622	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1055528003623	active site
1055528003624	phosphorylation site [posttranslational modification]
1055528003625	intermolecular recognition site; other site
1055528003626	dimerization interface [polypeptide binding]; other site
1055528003627	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1055528003628	DNA binding site [nucleotide binding]
1055528003629	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528003630	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528003631	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528003632	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528003633	Restriction endonuclease EcoRV; Region: Endonuc-EcoRV; pfam09233
1055528003634	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1055528003635	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055528003636	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528003637	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1055528003638	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055528003639	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528003640	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1055528003641	ATP binding site [chemical binding]; other site
1055528003642	putative Mg++ binding site [ion binding]; other site
1055528003643	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1055528003644	rod shape-determining protein MreC; Region: MreC; pfam04085
1055528003645	rod shape-determining protein MreB; Provisional; Region: PRK13927
1055528003646	MreB and similar proteins; Region: MreB_like; cd10225
1055528003647	nucleotide binding site [chemical binding]; other site
1055528003648	Mg binding site [ion binding]; other site
1055528003649	putative protofilament interaction site [polypeptide binding]; other site
1055528003650	RodZ interaction site [polypeptide binding]; other site
1055528003651	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
1055528003652	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
1055528003653	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1055528003654	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528003655	Walker A motif; other site
1055528003656	ATP binding site [chemical binding]; other site
1055528003657	Walker B motif; other site
1055528003658	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1055528003659	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1055528003660	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1055528003661	active site
1055528003662	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1055528003663	flagellar assembly protein FliW; Provisional; Region: PRK13282
1055528003664	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1055528003665	ATP-dependent protease La; Region: lon; TIGR00763
1055528003666	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528003667	Walker A motif; other site
1055528003668	ATP binding site [chemical binding]; other site
1055528003669	Walker B motif; other site
1055528003670	arginine finger; other site
1055528003671	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1055528003672	prephenate dehydrogenase; Validated; Region: PRK08507
1055528003673	Prephenate dehydrogenase; Region: PDH; pfam02153
1055528003674	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
1055528003675	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1055528003676	active site
1055528003677	substrate binding site [chemical binding]; other site
1055528003678	Mg2+ binding site [ion binding]; other site
1055528003679	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
1055528003680	DNA methylase; Region: N6_N4_Mtase; pfam01555
1055528003681	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055528003682	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
1055528003683	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1055528003684	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1055528003685	biotin synthase; Provisional; Region: PRK08508
1055528003686	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528003687	FeS/SAM binding site; other site
1055528003688	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1055528003689	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765
1055528003690	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
1055528003691	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1055528003692	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1055528003693	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
1055528003694	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1055528003695	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1055528003696	Ligand binding site; other site
1055528003697	metal-binding site
1055528003698	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
1055528003699	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1055528003700	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1055528003701	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
1055528003702	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1055528003703	Walker A motif/ATP binding site; other site
1055528003704	Walker B motif; other site
1055528003705	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
1055528003706	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1055528003707	ATP binding site [chemical binding]; other site
1055528003708	Walker A motif; other site
1055528003709	hexamer interface [polypeptide binding]; other site
1055528003710	Walker B motif; other site
1055528003711	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1055528003712	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1055528003713	active site
1055528003714	HIGH motif; other site
1055528003715	nucleotide binding site [chemical binding]; other site
1055528003716	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1055528003717	active site
1055528003718	KMSKS motif; other site
1055528003719	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1055528003720	tRNA binding surface [nucleotide binding]; other site
1055528003721	anticodon binding site; other site
1055528003722	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055528003723	RNA binding surface [nucleotide binding]; other site
1055528003724	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
1055528003725	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1055528003726	FeS/SAM binding site; other site
1055528003727	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1055528003728	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1055528003729	putative active site [active]
1055528003730	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1055528003731	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1055528003732	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1055528003733	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1055528003734	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1055528003735	dimethyladenosine transferase; Region: ksgA; TIGR00755
1055528003736	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528003737	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055528003738	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
1055528003739	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1055528003740	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1055528003741	active site
1055528003742	substrate binding site [chemical binding]; other site
1055528003743	cosubstrate binding site; other site
1055528003744	catalytic site [active]
1055528003745	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1055528003746	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1055528003747	tandem repeat interface [polypeptide binding]; other site
1055528003748	oligomer interface [polypeptide binding]; other site
1055528003749	active site residues [active]
1055528003750	TIR domain; Region: TIR_2; pfam13676
1055528003751	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1055528003752	active site
1055528003753	carbon storage regulator; Provisional; Region: PRK00568
1055528003754	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
1055528003755	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1055528003756	SmpB-tmRNA interface; other site
1055528003757	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
1055528003758	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1055528003759	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1055528003760	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1055528003761	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
1055528003762	hypothetical protein; Provisional; Region: PRK14374
1055528003763	membrane protein insertase; Provisional; Region: PRK01318
1055528003764	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1055528003765	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1055528003766	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1055528003767	tRNA modification GTPase TrmE; Region: mnmE_trmE_thdF; TIGR00450
1055528003768	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
1055528003769	GTP/Mg2+ binding site [chemical binding]; other site
1055528003770	G4 box; other site
1055528003771	G5 box; other site
1055528003772	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1055528003773	G1 box; other site
1055528003774	G1 box; other site
1055528003775	GTP/Mg2+ binding site [chemical binding]; other site
1055528003776	Switch I region; other site
1055528003777	Switch I region; other site
1055528003778	G2 box; other site
1055528003779	G2 box; other site
1055528003780	Switch II region; other site
1055528003781	G3 box; other site
1055528003782	G3 box; other site
1055528003783	Switch II region; other site
1055528003784	G4 box; other site
1055528003785	G5 box; other site
1055528003786	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1055528003787	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003788	LPP20 lipoprotein; Region: LPP20; pfam02169
1055528003789	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1055528003790	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1055528003791	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1055528003792	catalytic residues [active]
1055528003793	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1055528003794	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1055528003795	RNA binding surface [nucleotide binding]; other site
1055528003796	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1055528003797	active site
1055528003798	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1055528003799	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1055528003800	active site
1055528003801	PHP Thumb interface [polypeptide binding]; other site
1055528003802	metal binding site [ion binding]; metal-binding site
1055528003803	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1055528003804	generic binding surface I; other site
1055528003805	generic binding surface II; other site
1055528003806	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1055528003807	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
1055528003808	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1055528003809	mce related protein; Region: MCE; pfam02470
1055528003810	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1055528003811	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1055528003812	Walker A/P-loop; other site
1055528003813	ATP binding site [chemical binding]; other site
1055528003814	Q-loop/lid; other site
1055528003815	ABC transporter signature motif; other site
1055528003816	Walker B; other site
1055528003817	D-loop; other site
1055528003818	H-loop/switch region; other site
1055528003819	potential frameshift: common BLAST hit: gi|210135633|ref|YP_002302072.1| ABC transporter permease protein
1055528003820	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003821	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1055528003822	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1055528003823	homodimer interface [polypeptide binding]; other site
1055528003824	substrate-cofactor binding pocket; other site
1055528003825	catalytic residue [active]
1055528003826	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003827	DNA polymerase I; Region: pola; TIGR00593
1055528003828	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1055528003829	active site
1055528003830	metal binding site 1 [ion binding]; metal-binding site
1055528003831	putative 5' ssDNA interaction site; other site
1055528003832	metal binding site 3; metal-binding site
1055528003833	metal binding site 2 [ion binding]; metal-binding site
1055528003834	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1055528003835	putative DNA binding site [nucleotide binding]; other site
1055528003836	putative metal binding site [ion binding]; other site
1055528003837	3'-5' exonuclease; Region: 35EXOc; smart00474
1055528003838	active site
1055528003839	substrate binding site [chemical binding]; other site
1055528003840	catalytic site [active]
1055528003841	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1055528003842	active site
1055528003843	DNA binding site [nucleotide binding]
1055528003844	catalytic site [active]
1055528003845	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528003846	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528003847	VRR-NUC domain; Region: VRR_NUC; pfam08774
1055528003848	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1055528003849	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1055528003850	thymidylate kinase; Validated; Region: tmk; PRK00698
1055528003851	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1055528003852	TMP-binding site; other site
1055528003853	ATP-binding site [chemical binding]; other site
1055528003854	Phosphopantetheine adenylyltransferase [Coenzyme metabolism]; Region: CoaD; COG0669
1055528003855	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1055528003856	active site
1055528003857	(T/H)XGH motif; other site
1055528003858	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1055528003859	Flavoprotein; Region: Flavoprotein; pfam02441
1055528003860	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
1055528003861	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
1055528003862	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1055528003863	Part of AAA domain; Region: AAA_19; pfam13245
1055528003864	Family description; Region: UvrD_C_2; pfam13538
1055528003865	TPR repeat; Region: TPR_11; pfam13414
1055528003866	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055528003867	TPR motif; other site
1055528003868	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1055528003869	binding surface
1055528003870	TPR motif; other site
1055528003871	seryl-tRNA synthetase; Provisional; Region: PRK05431
1055528003872	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1055528003873	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1055528003874	dimer interface [polypeptide binding]; other site
1055528003875	active site
1055528003876	motif 1; other site
1055528003877	motif 2; other site
1055528003878	motif 3; other site
1055528003879	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1055528003880	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1055528003881	active site
1055528003882	catalytic triad [active]
1055528003883	dimer interface [polypeptide binding]; other site
1055528003884	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14065
1055528003885	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1055528003886	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528003887	S-adenosylmethionine binding site [chemical binding]; other site
1055528003888	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
1055528003889	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
1055528003890	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1055528003891	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1055528003892	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1055528003893	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1055528003894	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1055528003895	HlyD family secretion protein; Region: HlyD_3; pfam13437
1055528003896	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1055528003897	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1055528003898	Domain of unknown function DUF21; Region: DUF21; pfam01595
1055528003899	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1055528003900	Transporter associated domain; Region: CorC_HlyC; smart01091
1055528003901	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1055528003902	Phosphate transporter family; Region: PHO4; pfam01384
1055528003903	NifU-like domain; Region: NifU; pfam01106
1055528003904	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
1055528003905	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055528003906	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1055528003907	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
1055528003908	putative active site [active]
1055528003909	transaldolase; Provisional; Region: PRK03903
1055528003910	catalytic residue [active]
1055528003911	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
1055528003912	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1055528003913	5S rRNA interface [nucleotide binding]; other site
1055528003914	CTC domain interface [polypeptide binding]; other site
1055528003915	L16 interface [polypeptide binding]; other site
1055528003916	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1055528003917	putative active site [active]
1055528003918	catalytic residue [active]
1055528003919	Predicted permeases [General function prediction only]; Region: COG0795
1055528003920	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1055528003921	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1055528003922	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1055528003923	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1055528003924	AlwI restriction endonuclease; Region: RE_AlwI; pfam09491
1055528003925	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
1055528003927	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
1055528003928	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1055528003929	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1055528003930	metal-binding site [ion binding]
1055528003931	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1055528003932	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1055528003933	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1055528003934	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1055528003935	S-adenosylmethionine binding site [chemical binding]; other site
1055528003936	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1055528003937	catalytic motif [active]
1055528003938	Zn binding site [ion binding]; other site
1055528003939	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
1055528003940	RibD C-terminal domain; Region: RibD_C; cl17279
1055528003941	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1055528003942	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
1055528003943	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1055528003944	NAD(P) binding pocket [chemical binding]; other site
1055528003945	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
1055528003946	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1055528003947	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
1055528003948	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
1055528003949	FolB domain; Region: folB_dom; TIGR00526
1055528003950	active site
1055528003951	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
1055528003952	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1055528003953	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1055528003954	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1055528003955	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1055528003956	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1055528003957	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
1055528003958	NusA N-terminal domain; Region: NusA_N; pfam08529
1055528003959	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1055528003960	RNA binding site [nucleotide binding]; other site
1055528003961	homodimer interface [polypeptide binding]; other site
1055528003962	NusA-like KH domain; Region: KH_5; pfam13184
1055528003963	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1055528003964	G-X-X-G motif; other site
1055528003965	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
1055528003966	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1055528003967	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
1055528003968	putative active site [active]
1055528003969	putative NTP binding site [chemical binding]; other site
1055528003970	putative nucleic acid binding site [nucleotide binding]; other site
1055528003971	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1055528003972	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1055528003973	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1055528003974	Restriction endonuclease [Defense mechanisms]; Region: COG3587
1055528003975	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528003976	ATP binding site [chemical binding]; other site
1055528003977	putative Mg++ binding site [ion binding]; other site
1055528003978	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1055528003979	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
1055528003980	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1055528003981	ssDNA binding site; other site
1055528003982	generic binding surface II; other site
1055528003983	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528003984	ATP binding site [chemical binding]; other site
1055528003985	putative Mg++ binding site [ion binding]; other site
1055528003986	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055528003987	nucleotide binding region [chemical binding]; other site
1055528003988	ATP-binding site [chemical binding]; other site
1055528003989	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528003990	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1055528003991	active site
1055528003992	putative catalytic site [active]
1055528003993	DNA binding site [nucleotide binding]
1055528003994	putative phosphate binding site [ion binding]; other site
1055528003995	metal binding site A [ion binding]; metal-binding site
1055528003996	AP binding site [nucleotide binding]; other site
1055528003997	metal binding site B [ion binding]; metal-binding site
1055528003998	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1055528003999	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1055528004000	Walker A motif; other site
1055528004001	ATP binding site [chemical binding]; other site
1055528004002	Walker B motif; other site
1055528004003	arginine finger; other site
1055528004004	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1055528004005	DnaA box-binding interface [nucleotide binding]; other site
1055528004006	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1055528004007	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
1055528004008	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
1055528004009	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1055528004010	glutaminase active site [active]
1055528004011	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1055528004012	dimer interface [polypeptide binding]; other site
1055528004013	active site
1055528004014	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1055528004015	dimer interface [polypeptide binding]; other site
1055528004016	active site
1055528004017	Predicted alternative thymidylate synthase [Nucleotide transport and metabolism]; Region: THY1; COG1351
1055528004018	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528004019	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1055528004020	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1055528004021	Abi-like protein; Region: Abi_2; cl01988
1055528004022	potential frameshift: common BLAST hit: gi|308183636|ref|YP_003927763.1| type I restriction enzyme M protein (hsdM)
1055528004023	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1055528004024	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1055528004025	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528004026	ATP binding site [chemical binding]; other site
1055528004027	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055528004028	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1055528004029	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1055528004030	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1055528004031	ATP binding site [chemical binding]; other site
1055528004032	putative Mg++ binding site [ion binding]; other site
1055528004033	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1055528004034	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1055528004035	nucleotide binding region [chemical binding]; other site
1055528004036	ATP-binding site [chemical binding]; other site
1055528004037	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
1055528004038	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1055528004039	active site
1055528004040	metal binding site [ion binding]; metal-binding site
1055528004041	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1055528004042	domain I; other site
1055528004043	DNA binding groove [nucleotide binding]
1055528004044	phosphate binding site [ion binding]; other site
1055528004045	domain II; other site
1055528004046	domain III; other site
1055528004047	nucleotide binding site [chemical binding]; other site
1055528004048	catalytic site [active]
1055528004049	domain IV; other site
1055528004050	oxidoreductase; Region: PLN02991
1055528004051	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
1055528004052	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1055528004053	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1055528004054	P-loop; other site
1055528004055	Magnesium ion binding site [ion binding]; other site
1055528004056	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1055528004057	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
1055528004058	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1055528004059	Fic family protein [Function unknown]; Region: COG3177
1055528004060	Fic/DOC family; Region: Fic; pfam02661
1055528004061	potential frameshift: common BLAST hit: gi|308185145|ref|YP_003929278.1| integrase/recombinase (xerD)
1055528004062	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1055528004063	Protein of unknown function DUF45; Region: DUF45; pfam01863
1055528004064	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1055528004065	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1055528004066	N-terminal plug; other site
1055528004067	ligand-binding site [chemical binding]; other site
1055528004068	Arginase family; Region: Arginase; cd09989
1055528004069	active site
1055528004070	Mn binding site [ion binding]; other site
1055528004071	oligomer interface [polypeptide binding]; other site
1055528004072	S-methylmethionine transporter; Provisional; Region: PRK11387
1055528004073	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1055528004074	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1055528004075	hexamer interface [polypeptide binding]; other site
1055528004076	ligand binding site [chemical binding]; other site
1055528004077	putative active site [active]
1055528004078	NAD(P) binding site [chemical binding]; other site
1055528004079	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
1055528004080	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
1055528004081	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1055528004082	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1055528004083	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1055528004084	Walker A/P-loop; other site
1055528004085	ATP binding site [chemical binding]; other site
1055528004086	Q-loop/lid; other site
1055528004087	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1055528004088	ABC transporter signature motif; other site
1055528004089	Walker B; other site
1055528004090	D-loop; other site
1055528004091	H-loop/switch region; other site
1055528004092	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
1055528004093	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1055528004094	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
1055528004095	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1055528004096	active site
1055528004097	catalytic site [active]
1055528004098	substrate binding site [chemical binding]; other site
1055528004099	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1055528004100	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1055528004101	substrate binding site [chemical binding]; other site
1055528004102	hexamer interface [polypeptide binding]; other site
1055528004103	metal binding site [ion binding]; metal-binding site
1055528004104	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1055528004105	active site
1055528004106	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1055528004107	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1055528004108	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1055528004109	cofactor binding site; other site
1055528004110	DNA binding site [nucleotide binding]
1055528004111	substrate interaction site [chemical binding]; other site
1055528004112	elongation factor Ts; Provisional; Region: tsf; PRK09377
1055528004113	UBA/TS-N domain; Region: UBA; pfam00627
1055528004114	Elongation factor TS; Region: EF_TS; pfam00889
1055528004115	Elongation factor TS; Region: EF_TS; pfam00889
1055528004116	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1055528004117	rRNA interaction site [nucleotide binding]; other site
1055528004118	S8 interaction site; other site
1055528004119	putative laminin-1 binding site; other site
1055528004120	putative recombination protein RecB; Provisional; Region: PRK13909
1055528004121	Family description; Region: UvrD_C_2; pfam13538
1055528004122	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1055528004123	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
1055528004124	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1055528004125	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1055528004126	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1055528004127	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
1055528004128	Protein export membrane protein; Region: SecD_SecF; pfam02355
1055528004129	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1055528004130	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1055528004131	HIGH motif; other site
1055528004132	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1055528004133	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1055528004134	active site
1055528004135	KMSKS motif; other site
1055528004136	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1055528004137	tRNA binding surface [nucleotide binding]; other site
1055528004138	anticodon binding site; other site
1055528004139	Lipopolysaccharide-assembly; Region: LptE; pfam04390
1055528004140	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
1055528004141	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1055528004142	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1055528004143	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1055528004144	Peptidase family M23; Region: Peptidase_M23; pfam01551
1055528004145	potential frameshift: common BLAST hit: gi|188528341|ref|YP_001911028.1| toxR-activated gene (tagE)
1055528004146	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1055528004147	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1055528004148	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
1055528004149	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
1055528004150	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1055528004151	ATP binding site [chemical binding]; other site
1055528004152	putative Mg++ binding site [ion binding]; other site
1055528004153	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1055528004154	nucleotide binding region [chemical binding]; other site
1055528004155	ATP-binding site [chemical binding]; other site
1055528004156	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1055528004157	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
1055528004158	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1055528004159	iron-sulfur cluster [ion binding]; other site
1055528004160	[2Fe-2S] cluster binding site [ion binding]; other site
1055528004161	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
1055528004162	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1055528004163	intrachain domain interface; other site
1055528004164	interchain domain interface [polypeptide binding]; other site
1055528004165	heme bH binding site [chemical binding]; other site
1055528004166	Qi binding site; other site
1055528004167	heme bL binding site [chemical binding]; other site
1055528004168	Qo binding site; other site
1055528004169	interchain domain interface [polypeptide binding]; other site
1055528004170	intrachain domain interface; other site
1055528004171	Qi binding site; other site
1055528004172	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
1055528004173	Qo binding site; other site
1055528004174	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
1055528004175	Cytochrome c; Region: Cytochrom_C; pfam00034
1055528004176	Cytochrome c; Region: Cytochrom_C; cl11414
1055528004177	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1055528004178	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1055528004179	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1055528004180	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
1055528004181	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1055528004182	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055528004183	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1055528004184	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1055528004185	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
1055528004186	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1055528004187	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
1055528004188	putative ligand binding site [chemical binding]; other site
1055528004189	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
1055528004190	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1055528004191	putative ligand binding site [chemical binding]; other site
1055528004192	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1055528004193	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1055528004194	dimer interface [polypeptide binding]; other site
1055528004195	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1055528004196	catalytic triad [active]
1055528004197	peroxidatic and resolving cysteines [active]
1055528004198	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1055528004199	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1055528004200	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1055528004201	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1055528004202	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1055528004203	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1055528004204	G1 box; other site
1055528004205	GTP/Mg2+ binding site [chemical binding]; other site
1055528004206	Switch I region; other site
1055528004207	G2 box; other site
1055528004208	G3 box; other site
1055528004209	Switch II region; other site
1055528004210	G4 box; other site
1055528004211	G5 box; other site
1055528004212	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1055528004213	OstA-like protein; Region: OstA; pfam03968
1055528004214	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1055528004215	motif II; other site
1055528004216	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1055528004217	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1055528004218	Sporulation related domain; Region: SPOR; pfam05036
1055528004219	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1055528004220	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1055528004221	catalytic residue [active]
1055528004222	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1055528004223	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1055528004224	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1055528004225	active site
1055528004226	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
1055528004227	Lumazine binding domain; Region: Lum_binding; pfam00677
1055528004228	Lumazine binding domain; Region: Lum_binding; pfam00677
1055528004229	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
1055528004230	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1055528004231	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1055528004232	Walker A/P-loop; other site
1055528004233	ATP binding site [chemical binding]; other site
1055528004234	Q-loop/lid; other site
1055528004235	ABC transporter signature motif; other site
1055528004236	Walker B; other site
1055528004237	D-loop; other site
1055528004238	H-loop/switch region; other site
1055528004239	NIL domain; Region: NIL; pfam09383
1055528004240	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1055528004241	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1055528004242	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
1055528004243	active site
1055528004244	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1055528004245	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
1055528004246	Mg++ binding site [ion binding]; other site
1055528004247	putative catalytic motif [active]
1055528004248	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1055528004249	active site
1055528004250	hydrophilic channel; other site
1055528004251	dimerization interface [polypeptide binding]; other site
1055528004252	catalytic residues [active]
1055528004253	active site lid [active]
1055528004254	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1055528004255	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
1055528004256	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1055528004257	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
1055528004258	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1055528004259	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1055528004260	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1055528004261	hypothetical protein; Provisional; Region: PRK10236
1055528004262	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1055528004263	hypothetical protein; Provisional; Region: PRK10236
1055528004264	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1055528004265	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735