-- dump date 20140619_113718 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 570508000001 SEQ_END SEQ_END NC_011498.1 1673813 1673813 DR NC_011498.1; contig end 1673813..1673813 Helicobacter pylori P12 570508000002 SEQ_END SEQ_END NC_011499.1 10225 10225 DR NC_011499.1; contig end 10225..10225 Helicobacter pylori P12 YP_002300641.1 CDS nusB NC_011498.1 13 429 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(13..429) Helicobacter pylori P12 7011339 YP_002300642.1 CDS ribH NC_011498.1 431 901 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(431..901) Helicobacter pylori P12 7010365 YP_002300643.1 CDS kdsA NC_011498.1 911 1741 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(911..1741) Helicobacter pylori P12 7010366 YP_002300644.1 CDS HPP12_0004 NC_011498.1 1728 2393 R beta-carbonic anhydrase complement(1728..2393) Helicobacter pylori P12 7010367 YP_002300645.1 CDS pyrF NC_011498.1 2515 3198 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2515..3198 Helicobacter pylori P12 7010368 YP_002300646.1 CDS panC NC_011498.1 3199 4029 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3199..4029 Helicobacter pylori P12 7010369 YP_002300647.1 CDS hopZ NC_011498.1 5068 7167 R involved in adhesion; outer membrane protein HopZ complement(5068..7167) Helicobacter pylori P12 7010375 YP_002300648.1 CDS groEL NC_011498.1 7486 9126 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(7486..9126) Helicobacter pylori P12 7010376 YP_002300649.1 CDS groES NC_011498.1 9151 9507 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(9151..9507) Helicobacter pylori P12 7010377 YP_002300650.1 CDS dnaG NC_011498.1 9795 11474 D synthesizes RNA primers at the replication forks; DNA primase 9795..11474 Helicobacter pylori P12 7010378 YP_002300651.1 CDS HPP12_0011 NC_011498.1 11471 12523 D argininosuccinate synthase 11471..12523 Helicobacter pylori P12 7010379 YP_002300652.1 CDS HPP12_0012 NC_011498.1 12615 13442 D hypothetical protein 12615..13442 Helicobacter pylori P12 7010380 YP_002300653.1 CDS comB2 NC_011498.1 13587 13868 D ComB2 competence protein 13587..13868 Helicobacter pylori P12 7010381 YP_002300654.1 CDS comB3 NC_011498.1 13868 14131 D ComB3 competence protein 13868..14131 Helicobacter pylori P12 7010382 YP_002300655.1 CDS comB4 NC_011498.1 14133 16496 D ComB4 competence protein 14133..16496 Helicobacter pylori P12 7010383 YP_002300656.1 CDS HPP12_0016 NC_011498.1 16729 18138 D hypothetical protein 16729..18138 Helicobacter pylori P12 7010384 YP_002300657.1 CDS cheV-1 NC_011498.1 18238 19203 D chemotaxis signal transduction protein CheV 18238..19203 Helicobacter pylori P12 7010385 YP_002300658.1 CDS nspC NC_011498.1 19200 20417 D carboxynorspermidine decarboxylase 19200..20417 Helicobacter pylori P12 7010386 YP_002300659.1 CDS HPP12_0019 NC_011498.1 20436 21011 R inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase complement(20436..21011) Helicobacter pylori P12 7010387 YP_002300660.1 CDS HPP12_0020 NC_011498.1 21022 22587 R attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase complement(21022..22587) Helicobacter pylori P12 7010388 YP_002300661.1 CDS hopD NC_011498.1 23206 25338 R outer membrane protein HopD complement(23206..25338) Helicobacter pylori P12 7010389 YP_002300662.1 CDS gltA NC_011498.1 25872 27152 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(25872..27152) Helicobacter pylori P12 7010390 YP_002300663.1 CDS icd NC_011498.1 27354 28631 D isocitrate dehydrogenase 27354..28631 Helicobacter pylori P12 7010391 YP_002300664.1 CDS HPP12_0024 NC_011498.1 28693 29226 D hypothetical protein 28693..29226 Helicobacter pylori P12 7010392 YP_002300665.1 CDS bioD NC_011498.1 29203 29859 R dethiobiotin synthetase complement(29203..29859) Helicobacter pylori P12 7010393 YP_002300666.1 CDS HPP12_0026 NC_011498.1 29863 31623 R hypothetical protein complement(29863..31623) Helicobacter pylori P12 7010394 YP_002300667.1 CDS HPP12_0027 NC_011498.1 31734 32147 D hypothetical protein 31734..32147 Helicobacter pylori P12 7010395 YP_002300668.1 CDS clpS NC_011498.1 32183 32458 D ATP-dependent clp protease adapter protein ClpS 32183..32458 Helicobacter pylori P12 7010396 YP_002300669.1 CDS clpA NC_011498.1 32458 34683 D ATP-binding subunit, chaperone protein; ATP-dependent clp protease 32458..34683 Helicobacter pylori P12 7010397 YP_002300670.1 CDS panD NC_011498.1 34673 35023 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 34673..35023 Helicobacter pylori P12 7010398 YP_002300671.1 CDS HPP12_0031 NC_011498.1 35034 35327 D hypothetical protein 35034..35327 Helicobacter pylori P12 7010399 YP_002300672.1 CDS HPP12_0032 NC_011498.1 35327 36331 D hypothetical protein 35327..36331 Helicobacter pylori P12 7010400 YP_002300673.1 CDS comB6 NC_011498.1 36339 37394 D ComB6 competence protein 36339..37394 Helicobacter pylori P12 7010401 YP_002300674.1 CDS comb7 NC_011498.1 37410 37523 D Comb7 competence protein 37410..37523 Helicobacter pylori P12 7010402 YP_002300675.1 CDS comB8 NC_011498.1 37520 38263 D ComB8 competence protein 37520..38263 Helicobacter pylori P12 7010403 YP_002300676.1 CDS comB9 NC_011498.1 38263 39249 D ComB9 competence protein 38263..39249 Helicobacter pylori P12 7010404 YP_002300677.1 CDS comB10 NC_011498.1 39242 40378 D ComB10 competence protein 39242..40378 Helicobacter pylori P12 7010405 YP_002300678.1 CDS HPP12_0038 NC_011498.1 40448 41767 D bifunctional mannose-6-phosphate isomerase / mannose-1-phosphate guanylyltransferase 40448..41767 Helicobacter pylori P12 7010406 YP_002300679.1 CDS gmd NC_011498.1 41888 43033 D GDP-D-mannose dehydratase 41888..43033 Helicobacter pylori P12 7010407 YP_002300680.1 CDS HPP12_0040 NC_011498.1 43026 43958 D GDP-fucose synthetase 43026..43958 Helicobacter pylori P12 7010408 YP_002300681.1 CDS hypE NC_011498.1 44876 45874 R hydrogenase expression/formation protein complement(44876..45874) Helicobacter pylori P12 7010409 YP_002300682.1 CDS hypF NC_011498.1 45877 48150 R transcriptional regulatory protein HypF complement(45877..48150) Helicobacter pylori P12 7010410 YP_002300683.1 CDS HPP12_0043 NC_011498.1 48126 49118 R peptidylarginine deiminase domain-containing protein complement(48126..49118) Helicobacter pylori P12 7010411 YP_002300684.1 CDS dpnA NC_011498.1 49177 49869 R adenine specific DNA methyltransferase complement(49177..49869) Helicobacter pylori P12 7010412 YP_002300685.1 CDS ddeM NC_011498.1 49866 50933 R cytosine specific DNA methyltransferase complement(49866..50933) Helicobacter pylori P12 7010413 YP_002300686.1 CDS HPP12_0046 NC_011498.1 50930 52153 R restriction endonuclease complement(50930..52153) Helicobacter pylori P12 7010414 YP_002300687.1 CDS HPP12_0047 NC_011498.1 52297 53568 R type II R-M system restriction endonuclease complement(52297..53568) Helicobacter pylori P12 7010415 YP_002300688.1 CDS HPP12_0048 NC_011498.1 53568 56036 R type II R-M system methyltransferase complement(53568..56036) Helicobacter pylori P12 7010416 YP_002300689.1 CDS putP NC_011498.1 56076 57566 R sodium/proline symporter complement(56076..57566) Helicobacter pylori P12 7010417 YP_002300690.1 CDS putA NC_011498.1 57593 61150 R proline/delta 1-pyrroline-5-carboxylate dehydrogenase complement(57593..61150) Helicobacter pylori P12 7010418 YP_002300691.1 CDS HPP12_0051 NC_011498.1 61472 61681 D hypothetical protein 61472..61681 Helicobacter pylori P12 7010419 YP_002300692.1 CDS HPP12_0052 NC_011498.1 61982 62353 D hypothetical protein 61982..62353 Helicobacter pylori P12 7010420 YP_002300693.1 CDS HPP12_0053 NC_011498.1 62425 62589 D hypothetical protein 62425..62589 Helicobacter pylori P12 7010421 YP_002300694.1 CDS HPP12_0054 NC_011498.1 62547 62735 D hypothetical protein 62547..62735 Helicobacter pylori P12 7010422 YP_002300695.1 CDS HPP12_0055 NC_011498.1 62737 63678 D hypothetical protein 62737..63678 Helicobacter pylori P12 7010423 YP_002300696.1 CDS HPP12_0056 NC_011498.1 63713 64477 D hypothetical protein 63713..64477 Helicobacter pylori P12 7010424 YP_002300697.1 CDS HPP12_0057 NC_011498.1 64478 64630 D hypothetical protein 64478..64630 Helicobacter pylori P12 7010425 YP_002300698.1 CDS HPP12_0058 NC_011498.1 64688 64816 D hypothetical protein 64688..64816 Helicobacter pylori P12 7010426 YP_002300699.1 CDS HPP12_0059 NC_011498.1 64944 65150 D hypothetical protein 64944..65150 Helicobacter pylori P12 7010427 YP_002300700.1 CDS HPP12_0060 NC_011498.1 65194 66138 D hypothetical protein 65194..66138 Helicobacter pylori P12 7010428 YP_002300701.1 CDS HPP12_0061 NC_011498.1 66135 66698 D hypothetical protein 66135..66698 Helicobacter pylori P12 7010429 YP_002300702.1 CDS HPP12_0062 NC_011498.1 66714 66974 D hypothetical protein 66714..66974 Helicobacter pylori P12 7010430 YP_002300703.1 CDS HPP12_0063 NC_011498.1 67070 67612 D hypothetical protein 67070..67612 Helicobacter pylori P12 7010431 YP_002300704.1 CDS HPP12_0064 NC_011498.1 67609 68493 D hypothetical protein 67609..68493 Helicobacter pylori P12 7010432 YP_002300705.1 CDS HPP12_0065 NC_011498.1 68463 68888 D CdrA-like fragment; hypothetical protein 68463..68888 Helicobacter pylori P12 7010433 YP_002300706.1 CDS HPP12_0066 NC_011498.1 68890 69237 D hypothetical protein 68890..69237 Helicobacter pylori P12 7010434 YP_002300707.1 CDS HPP12_0067 NC_011498.1 69230 69658 D ATP-binding protein 69230..69658 Helicobacter pylori P12 7010435 YP_002300708.1 CDS HPP12_0068 NC_011498.1 69809 70129 D ATP-binding protein 69809..70129 Helicobacter pylori P12 7010436 YP_002300709.1 CDS HPP12_0069 NC_011498.1 70221 70346 D ATP-binding protein 70221..70346 Helicobacter pylori P12 7010437 YP_002300710.1 CDS HPP12_0070 NC_011498.1 70353 71651 D ATP-binding protein 70353..71651 Helicobacter pylori P12 7010438 YP_002300711.1 CDS ureH NC_011498.1 71708 72505 R urease accessory protein UreH complement(71708..72505) Helicobacter pylori P12 7010439 YP_002300712.1 CDS ureG NC_011498.1 72505 73104 R urease accessory protein UreG complement(72505..73104) Helicobacter pylori P12 7010440 YP_002300713.1 CDS ureF NC_011498.1 73133 73897 R urease accessory protein UreF complement(73133..73897) Helicobacter pylori P12 7010441 YP_002300714.1 CDS ureE NC_011498.1 73909 74421 R involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE complement(73909..74421) Helicobacter pylori P12 7010442 YP_002300715.1 CDS ureI NC_011498.1 74423 75010 R ph-dependent urea-transporter; urease accessory protein UreI complement(74423..75010) Helicobacter pylori P12 7010443 YP_002300716.1 CDS ureB NC_011498.1 75203 76912 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta complement(75203..76912) Helicobacter pylori P12 7010444 YP_002300717.1 CDS ureA NC_011498.1 76916 77632 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha complement(76916..77632) Helicobacter pylori P12 7010445 YP_002300718.1 CDS lspA NC_011498.1 77977 78450 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(77977..78450) Helicobacter pylori P12 7010447 YP_002300719.1 CDS glmM NC_011498.1 78444 79781 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(78444..79781) Helicobacter pylori P12 7010448 YP_002300720.1 CDS rpsT NC_011498.1 79871 80140 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 79871..80140 Helicobacter pylori P12 7010449 YP_002300721.1 CDS prfA NC_011498.1 80264 81322 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 80264..81322 Helicobacter pylori P12 7010450 YP_002300722.1 CDS HPP12_0082 NC_011498.1 81711 81968 D hypothetical protein 81711..81968 Helicobacter pylori P12 7010451 YP_002300723.1 CDS horA NC_011498.1 81979 83373 D outer membrane protein HorA 81979..83373 Helicobacter pylori P12 7010452 YP_002300724.1 CDS HPP12_0084 NC_011498.1 83620 85365 D hypothetical protein 83620..85365 Helicobacter pylori P12 7010453 YP_002300725.1 CDS HPP12_0085 NC_011498.1 85777 87726 R methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) complement(85777..87726) Helicobacter pylori P12 7010454 YP_002300726.1 CDS rpsI NC_011498.1 87954 88343 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(87954..88343) Helicobacter pylori P12 7010455 YP_002300727.1 CDS rplM NC_011498.1 88340 88765 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(88340..88765) Helicobacter pylori P12 7010456 YP_002300728.1 CDS HPP12_0088 NC_011498.1 89077 89265 R hypothetical protein complement(89077..89265) Helicobacter pylori P12 7010457 YP_002300729.1 CDS HPP12_0089 NC_011498.1 89272 90624 R malate:quinone oxidoreductase complement(89272..90624) Helicobacter pylori P12 7010458 YP_002300730.1 CDS HPP12_0090 NC_011498.1 90678 92051 R hypothetical protein complement(90678..92051) Helicobacter pylori P12 7010459 YP_002300731.1 CDS rpoD NC_011498.1 92072 94114 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(92072..94114) Helicobacter pylori P12 7010460 YP_002300732.1 CDS HPP12_0092 NC_011498.1 94303 94998 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(94303..94998) Helicobacter pylori P12 7010461 YP_002300733.1 CDS fabD NC_011498.1 95009 95938 R malonyl coenzyme A-acyl carrier protein transacylase complement(95009..95938) Helicobacter pylori P12 7010462 YP_002300734.1 CDS HPP12_0094 NC_011498.1 96364 97140 D type II R-M system restriction endonuclease 96364..97140 Helicobacter pylori P12 7010464 YP_002300735.1 CDS HPP12_0095 NC_011498.1 97190 98038 D type II R-M system methyltransferase 97190..98038 Helicobacter pylori P12 7010465 YP_002300736.1 CDS HPP12_0096 NC_011498.1 98045 98944 R alpha-1,2-fucosyltransferase complement(98045..98944) Helicobacter pylori P12 7010466 YP_002300737.1 CDS HPP12_0097 NC_011498.1 99044 99574 R hypothetical protein complement(99044..99574) Helicobacter pylori P12 7010467 YP_002300738.1 CDS HPP12_0098 NC_011498.1 99647 100591 D Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 99647..100591 Helicobacter pylori P12 7010468 YP_002300739.1 CDS HPP12_0099 NC_011498.1 100797 101510 R hypothetical protein complement(100797..101510) Helicobacter pylori P12 7010469 YP_002300740.1 CDS thrC NC_011498.1 101617 103071 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(101617..103071) Helicobacter pylori P12 7010470 YP_002300741.1 CDS tlpA NC_011498.1 103274 105301 D methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) 103274..105301 Helicobacter pylori P12 7010471 YP_002300742.1 CDS HPP12_0102 NC_011498.1 105301 106407 D hypothetical protein 105301..106407 Helicobacter pylori P12 7010472 YP_002300743.1 CDS HPP12_0103 NC_011498.1 106526 107287 D hypothetical protein 106526..107287 Helicobacter pylori P12 7010473 YP_002300744.1 CDS HPP12_0104 NC_011498.1 107270 108052 R glycosyl transferase complement(107270..108052) Helicobacter pylori P12 7010474 YP_002300745.1 CDS tlpB NC_011498.1 108084 109769 R methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) complement(108084..109769) Helicobacter pylori P12 7010475 YP_002300746.1 CDS cpdB NC_011498.1 109981 111726 R 2',3'-cyclic-nucleotide 2'-phosphodiesterase complement(109981..111726) Helicobacter pylori P12 7010476 YP_002300747.1 CDS HPP12_0107 NC_011498.1 111867 112334 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(111867..112334) Helicobacter pylori P12 7010477 YP_002300748.1 CDS metB NC_011498.1 112372 113514 R catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase/cystathionine beta-lyase complement(112372..113514) Helicobacter pylori P12 7010478 YP_002300749.1 CDS cysK NC_011498.1 113539 114456 R cysteine synthetase complement(113539..114456) Helicobacter pylori P12 7010479 YP_002300750.1 CDS HPP12_0110 NC_011498.1 114571 115056 D hypothetical protein 114571..115056 Helicobacter pylori P12 7010480 YP_002300751.1 CDS dnaK NC_011498.1 115386 117248 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(115386..117248) Helicobacter pylori P12 7010481 YP_002300752.1 CDS grpE NC_011498.1 117279 117854 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(117279..117854) Helicobacter pylori P12 7010482 YP_002300753.1 CDS HPP12_0113 NC_011498.1 117854 118684 R Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor complement(117854..118684) Helicobacter pylori P12 7010483 YP_002300754.1 CDS HPP12_0114 NC_011498.1 118895 119533 D hypothetical protein 118895..119533 Helicobacter pylori P12 7010484 YP_002300755.1 CDS HPP12_0115 NC_011498.1 119554 119850 D hypothetical protein 119554..119850 Helicobacter pylori P12 7010485 YP_002300756.1 CDS HPP12_0116 NC_011498.1 119862 121745 R hypothetical protein complement(119862..121745) Helicobacter pylori P12 7010486 YP_002300757.1 CDS flaB NC_011498.1 121808 123352 R FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B complement(121808..123352) Helicobacter pylori P12 7010487 YP_002300758.1 CDS topA-1 NC_011498.1 123518 125728 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 123518..125728 Helicobacter pylori P12 7010488 YP_002300759.1 CDS HPP12_0119 NC_011498.1 125721 126647 D radical SAM domain-containing protein 125721..126647 Helicobacter pylori P12 7010489 YP_002300760.1 CDS HPP12_0120 NC_011498.1 126786 128003 R hypothetical protein complement(126786..128003) Helicobacter pylori P12 7010490 YP_002300761.1 CDS ppsA NC_011498.1 128113 130539 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(128113..130539) Helicobacter pylori P12 7010491 YP_002300762.1 CDS HPP12_0122 NC_011498.1 130707 130856 D hypothetical protein 130707..130856 Helicobacter pylori P12 7010492 YP_002300763.1 CDS thrS NC_011498.1 130897 132735 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 130897..132735 Helicobacter pylori P12 7010493 YP_002300764.1 CDS infC NC_011498.1 132732 133343 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 132732..133343 Helicobacter pylori P12 7010494 YP_002300765.1 CDS rpmI NC_011498.1 133324 133518 D 50S ribosomal protein L35 133324..133518 Helicobacter pylori P12 7010495 YP_002300766.1 CDS rplT NC_011498.1 133612 133962 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 133612..133962 Helicobacter pylori P12 7010496 YP_002300767.1 CDS horB NC_011498.1 134162 135022 D outer membrane protein HorB 134162..135022 Helicobacter pylori P12 7010497 YP_002300768.1 CDS HPP12_0128 NC_011498.1 135383 135820 D hypothetical protein 135383..135820 Helicobacter pylori P12 7010498 YP_002300769.1 CDS HPP12_0129 NC_011498.1 136225 137088 D hypothetical protein 136225..137088 Helicobacter pylori P12 7010499 YP_002300770.1 CDS HPP12_0130 NC_011498.1 137728 139095 R L-serine/L-threonine deaminase complement(137728..139095) Helicobacter pylori P12 7010500 YP_002300771.1 CDS sdaC NC_011498.1 139095 140336 R L-serine transporter complement(139095..140336) Helicobacter pylori P12 7010501 YP_002300772.1 CDS HPP12_0132 NC_011498.1 140630 141979 D tyrosine-regulated 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHP synthase) 140630..141979 Helicobacter pylori P12 7010502 YP_002300773.1 CDS HPP12_0133 NC_011498.1 142269 142403 D hypothetical protein 142269..142403 Helicobacter pylori P12 7010503 YP_002300774.1 CDS bcp NC_011498.1 142646 143104 R bacterioferritin comigratory protein complement(142646..143104) Helicobacter pylori P12 7010504 YP_002300775.1 CDS HPP12_0135 NC_011498.1 143114 143749 R hypothetical protein complement(143114..143749) Helicobacter pylori P12 7010505 YP_002300776.1 CDS HPP12_0136 NC_011498.1 143742 145187 R iron-sulfur electron transport protein complement(143742..145187) Helicobacter pylori P12 7010506 YP_002300777.1 CDS HPP12_0137 NC_011498.1 145216 145944 R Fe-S oxidoreductase complement(145216..145944) Helicobacter pylori P12 7010507 YP_002300778.1 CDS lldP-1 NC_011498.1 146167 147816 D L-lactate permease 146167..147816 Helicobacter pylori P12 7010508 YP_002300779.1 CDS lldP-2 NC_011498.1 147873 149528 D L-lactate permease 147873..149528 Helicobacter pylori P12 7010509 YP_002300780.1 CDS HPP12_0140 NC_011498.1 149479 149784 R hypothetical protein complement(149479..149784) Helicobacter pylori P12 7010510 YP_002300781.1 CDS mutY NC_011498.1 149774 150643 R DNA glycosylase MutY complement(149774..150643) Helicobacter pylori P12 7010511 YP_002300782.1 CDS HPP12_0142 NC_011498.1 150761 152209 R sodium:sulfate symporter transmembrane region domain-containing protein complement(150761..152209) Helicobacter pylori P12 7010512 YP_002300783.1 CDS fixN NC_011498.1 152379 153845 D CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 152379..153845 Helicobacter pylori P12 7010513 YP_002300784.1 CDS fixO NC_011498.1 153858 154556 D CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 153858..154556 Helicobacter pylori P12 7010514 YP_002300785.1 CDS fixQ NC_011498.1 154567 154785 D cytochrome C oxidase subunit Q 154567..154785 Helicobacter pylori P12 7010515 YP_002300786.1 CDS fixP NC_011498.1 154787 155665 D cytochrome C oxidase diheme subunit 154787..155665 Helicobacter pylori P12 7010516 YP_002300787.1 CDS HPP12_0147 NC_011498.1 155676 155882 D hypothetical protein 155676..155882 Helicobacter pylori P12 7010517 YP_002300788.1 CDS HPP12_0148 NC_011498.1 155983 156570 D hypothetical protein 155983..156570 Helicobacter pylori P12 7010518 YP_002300789.1 CDS HPP12_0149 NC_011498.1 156582 157163 D hypothetical protein 156582..157163 Helicobacter pylori P12 7010519 YP_002300790.1 CDS HPP12_0150 NC_011498.1 157250 158017 D hypothetical protein 157250..158017 Helicobacter pylori P12 7010520 YP_002300791.1 CDS HPP12_0151 NC_011498.1 158014 158877 R hypothetical protein complement(158014..158877) Helicobacter pylori P12 7010521 YP_002300792.1 CDS recA NC_011498.1 158975 160018 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 158975..160018 Helicobacter pylori P12 7010522 YP_002300793.1 CDS eno NC_011498.1 160030 161310 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 160030..161310 Helicobacter pylori P12 7010523 YP_002300794.1 CDS HPP12_0154 NC_011498.1 161303 161578 D hypothetical protein 161303..161578 Helicobacter pylori P12 7010524 YP_002300795.1 CDS HPP12_0155 NC_011498.1 161595 162191 D hypothetical protein 161595..162191 Helicobacter pylori P12 7010525 YP_002300796.1 CDS aroK NC_011498.1 162196 162684 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 162196..162684 Helicobacter pylori P12 7010526 YP_002300797.1 CDS HPP12_0157 NC_011498.1 162706 163662 D general glycosylation pathway protein 162706..163662 Helicobacter pylori P12 7010527 YP_002300798.1 CDS HPP12_0158 NC_011498.1 163659 164762 R lipopolysaccharide 1,2-glycosyltransferase complement(163659..164762) Helicobacter pylori P12 7010528 YP_002300799.1 CDS hcpD NC_011498.1 164914 165834 D cysteine-rich protein D 164914..165834 Helicobacter pylori P12 7010529 YP_002300800.1 CDS HPP12_0160 NC_011498.1 166362 167084 R hypothetical protein complement(166362..167084) Helicobacter pylori P12 7010530 YP_002300801.1 CDS hemB NC_011498.1 167085 168056 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(167085..168056) Helicobacter pylori P12 7010531 YP_002300802.1 CDS HPP12_0162 NC_011498.1 168066 169409 R histidine kinase sensor protein complement(168066..169409) Helicobacter pylori P12 7010532 YP_002300803.1 CDS ompR NC_011498.1 169435 170112 R response regulator complement(169435..170112) Helicobacter pylori P12 7010533 YP_002300804.1 CDS HPP12_0164 NC_011498.1 170348 170824 R hypothetical protein complement(170348..170824) Helicobacter pylori P12 7010534 YP_002300805.1 CDS HPP12_0165 NC_011498.1 170803 171066 R hypothetical protein complement(170803..171066) Helicobacter pylori P12 7010535 YP_002300806.1 CDS HPP12_0166 NC_011498.1 171096 172376 R collagenase complement(171096..172376) Helicobacter pylori P12 7010536 YP_002300807.1 CDS HPP12_0167 NC_011498.1 172379 173086 R hypothetical protein complement(172379..173086) Helicobacter pylori P12 7010537 YP_002300808.1 CDS prfB NC_011498.1 173156 174247 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(173156..174247) Helicobacter pylori P12 7010538 YP_002300809.1 CDS moeA NC_011498.1 174308 175483 R molybdopterin biosynthesis protein complement(174308..175483) Helicobacter pylori P12 7010539 YP_002300810.1 CDS fliR NC_011498.1 175493 176260 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(175493..176260) Helicobacter pylori P12 7010540 YP_002300811.1 CDS HPP12_0171 NC_011498.1 176254 176982 R hypothetical protein complement(176254..176982) Helicobacter pylori P12 7010541 YP_002300812.1 CDS HPP12_0172 NC_011498.1 177456 178355 D peptidyl-prolyl cis-trans isomerase C 177456..178355 Helicobacter pylori P12 7010542 YP_002300813.1 CDS fba NC_011498.1 178372 179295 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 178372..179295 Helicobacter pylori P12 7010543 YP_002300814.1 CDS efp NC_011498.1 179317 179880 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 179317..179880 Helicobacter pylori P12 7010544 YP_002300815.1 CDS HPP12_0175 NC_011498.1 180329 180772 R hypothetical protein complement(180329..180772) Helicobacter pylori P12 7010545 YP_002300816.1 CDS HPP12_0176 NC_011498.1 180968 181249 D hypothetical protein 180968..181249 Helicobacter pylori P12 7010546 YP_002300817.1 CDS HPP12_0177 NC_011498.1 181258 181527 D hypothetical protein 181258..181527 Helicobacter pylori P12 7010547 YP_002300818.1 CDS HPP12_0178 NC_011498.1 181882 182904 R sialic acid synthase complement(181882..182904) Helicobacter pylori P12 7010548 YP_002300819.1 CDS HPP12_0179 NC_011498.1 182908 183549 R ABC transporter ATP-binding protein complement(182908..183549) Helicobacter pylori P12 7010549 YP_002300820.1 CDS HPP12_0180 NC_011498.1 183546 184823 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(183546..184823) Helicobacter pylori P12 7010550 YP_002300821.1 CDS HPP12_0181 NC_011498.1 185054 185776 D hypothetical protein 185054..185776 Helicobacter pylori P12 7010551 YP_002300822.1 CDS lysS NC_011498.1 185786 187291 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 185786..187291 Helicobacter pylori P12 7010552 YP_002300823.1 CDS glyA NC_011498.1 187291 188541 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 187291..188541 Helicobacter pylori P12 7010553 YP_002300824.1 CDS HPP12_0184 NC_011498.1 188552 189094 D hypothetical protein 188552..189094 Helicobacter pylori P12 7010554 YP_002300825.1 CDS HPP12_0185 NC_011498.1 189116 189925 D hypothetical protein 189116..189925 Helicobacter pylori P12 7010555 YP_002300826.1 CDS HPP12_0186 NC_011498.1 190314 191033 R hypothetical protein complement(190314..191033) Helicobacter pylori P12 7010556 YP_002300827.1 CDS HPP12_0187 NC_011498.1 191073 191534 R hypothetical protein complement(191073..191534) Helicobacter pylori P12 7010557 YP_002300828.1 CDS HPP12_0188 NC_011498.1 191535 191867 R hypothetical protein complement(191535..191867) Helicobacter pylori P12 7010558 YP_002300829.1 CDS HPP12_0189 NC_011498.1 191854 192030 R hypothetical protein complement(191854..192030) Helicobacter pylori P12 7010559 YP_002300830.1 CDS HPP12_0190 NC_011498.1 192189 192722 D hypothetical protein 192189..192722 Helicobacter pylori P12 7010560 YP_002300831.1 CDS HPP12_0191 NC_011498.1 192728 194236 R phospholipase D-family protein complement(192728..194236) Helicobacter pylori P12 7010561 YP_002300832.1 CDS frdB NC_011498.1 194258 194995 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(194258..194995) Helicobacter pylori P12 7010562 YP_002300833.1 CDS frdA NC_011498.1 194988 197132 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(194988..197132) Helicobacter pylori P12 7010563 YP_002300834.1 CDS frdC NC_011498.1 197142 197909 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit complement(197142..197909) Helicobacter pylori P12 7010564 YP_002300835.1 CDS tpiA NC_011498.1 198115 198819 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 198115..198819 Helicobacter pylori P12 7010565 YP_002300836.1 CDS fabI NC_011498.1 198829 199662 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 198829..199662 Helicobacter pylori P12 7010566 YP_002300837.1 CDS lpxD NC_011498.1 199662 200672 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 199662..200672 Helicobacter pylori P12 7010567 YP_002300838.1 CDS metK NC_011498.1 200737 201894 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 200737..201894 Helicobacter pylori P12 7010568 YP_002300839.1 CDS ndk NC_011498.1 201961 202374 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 201961..202374 Helicobacter pylori P12 7010569 YP_002300840.1 CDS HPP12_0200 NC_011498.1 202400 202756 D hypothetical protein 202400..202756 Helicobacter pylori P12 7010570 YP_002300841.1 CDS rpmF NC_011498.1 202772 202918 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 202772..202918 Helicobacter pylori P12 7010571 YP_002300842.1 CDS plsX NC_011498.1 202985 204004 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 202985..204004 Helicobacter pylori P12 7010572 YP_002300843.1 CDS fabH NC_011498.1 204029 205021 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 204029..205021 Helicobacter pylori P12 7010573 YP_002300844.1 CDS HPP12_0204 NC_011498.1 205042 205344 D hypothetical protein 205042..205344 Helicobacter pylori P12 7010574 YP_002300845.1 CDS HPP12_0205 NC_011498.1 205634 206017 R hypothetical protein complement(205634..206017) Helicobacter pylori P12 7010575 YP_002300846.1 CDS HPP12_0206 NC_011498.1 206033 208924 R hypothetical protein complement(206033..208924) Helicobacter pylori P12 7010576 YP_002300847.1 CDS HPP12_0207 NC_011498.1 208897 209211 R hypothetical protein complement(208897..209211) Helicobacter pylori P12 7010577 YP_002300848.1 CDS HPP12_0208 NC_011498.1 209308 210414 D ATP/GTP-binding protein; mrp related protein 209308..210414 Helicobacter pylori P12 7010578 YP_002300849.1 CDS hofA NC_011498.1 211741 213093 D outer membrane protein HofA 211741..213093 Helicobacter pylori P12 7010580 YP_002300850.1 CDS htpG NC_011498.1 213196 215061 D molecular chaperone; heat shock protein 90 213196..215061 Helicobacter pylori P12 7010581 YP_002300851.1 CDS hcpA NC_011498.1 215259 216011 R cysteine-rich protein A complement(215259..216011) Helicobacter pylori P12 7010582 YP_002300852.1 CDS dapE NC_011498.1 216092 217243 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(216092..217243) Helicobacter pylori P12 7010583 YP_002300853.1 CDS gidA NC_011498.1 217254 219119 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(217254..219119) Helicobacter pylori P12 7010584 YP_002300854.1 CDS HPP12_0215 NC_011498.1 219215 220861 D sodium-dependent transporter 219215..220861 Helicobacter pylori P12 7010585 YP_002300855.1 CDS cdsA NC_011498.1 220874 221674 D cdp-diacylglycerol synthetase 220874..221674 Helicobacter pylori P12 7010586 YP_002300856.1 CDS HPP12_0217 NC_011498.1 221675 222781 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 221675..222781 Helicobacter pylori P12 7010587 YP_002300857.1 CDS HPP12_0218 NC_011498.1 222832 223960 D beta-1,4-N-acetylgalactosamyltransferase join(222832..223119,223121..223960) Helicobacter pylori P12 7010588 YP_002300858.1 CDS HPP12_0219 NC_011498.1 224028 224579 R phospholipid-binding protein complement(224028..224579) Helicobacter pylori P12 7010589 YP_002300859.1 CDS HPP12_0220 NC_011498.1 224725 225186 D hypothetical protein 224725..225186 Helicobacter pylori P12 7010590 YP_002300860.1 CDS HPP12_0221 NC_011498.1 225356 226519 D involved in [Fe-s] cluster synthesis; cysteine desulfurase 225356..226519 Helicobacter pylori P12 7010591 YP_002300861.1 CDS HPP12_0222 NC_011498.1 226541 227521 D nifu-like protein 226541..227521 Helicobacter pylori P12 7010592 YP_002300862.1 CDS HPP12_0223 NC_011498.1 227774 227908 D hypothetical protein 227774..227908 Helicobacter pylori P12 7010593 YP_002300863.1 CDS radA NC_011498.1 228020 229366 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 228020..229366 Helicobacter pylori P12 7010594 YP_002300864.1 CDS HPP12_0225 NC_011498.1 229490 230569 D peptide methionine sulfoxide reductase 229490..230569 Helicobacter pylori P12 7010595 YP_002300865.1 CDS HPP12_0226 NC_011498.1 230920 231753 R integral membrane protein complement(230920..231753) Helicobacter pylori P12 7010596 YP_002300866.1 CDS hopM NC_011498.1 231966 234053 R outer membrane protein HopM complement(231966..234053) Helicobacter pylori P12 7010597 YP_002300867.1 CDS HPP12_0228 NC_011498.1 234301 235458 D sulfate permease 234301..235458 Helicobacter pylori P12 7010598 YP_002300868.1 CDS hopA NC_011498.1 235702 237165 R outer membrane protein HopA complement(235702..237165) Helicobacter pylori P12 7010600 YP_002300869.1 CDS kdsB NC_011498.1 237352 238083 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(237352..238083) Helicobacter pylori P12 7010601 YP_002300870.1 CDS HPP12_0231 NC_011498.1 238193 238990 D disulphide isomerase 238193..238990 Helicobacter pylori P12 7010602 YP_002300871.1 CDS HPP12_0232 NC_011498.1 239006 239659 D hypothetical protein 239006..239659 Helicobacter pylori P12 7010603 YP_002300872.1 CDS HPP12_0233 NC_011498.1 239683 240855 D glutathionespermidine synthetase 239683..240855 Helicobacter pylori P12 7010604 YP_002300873.1 CDS HPP12_0234 NC_011498.1 240855 241385 D integral membrane protein 240855..241385 Helicobacter pylori P12 7010605 YP_002300874.1 CDS hcpE NC_011498.1 242155 243216 R cysteine-rich protein E complement(242155..243216) Helicobacter pylori P12 7010606 YP_002300875.1 CDS HPP12_0236 NC_011498.1 243309 243680 R hypothetical protein complement(243309..243680) Helicobacter pylori P12 7010607 YP_002300876.1 CDS hemC NC_011498.1 243680 244600 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(243680..244600) Helicobacter pylori P12 7010608 YP_002300877.1 CDS proS NC_011498.1 244611 246344 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(244611..246344) Helicobacter pylori P12 7010609 YP_002300878.1 CDS hemA NC_011498.1 246348 247697 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(246348..247697) Helicobacter pylori P12 7010610 YP_002300879.1 CDS ispB NC_011498.1 247697 248620 R octaprenyl-diphosphate synthase complement(247697..248620) Helicobacter pylori P12 7010611 YP_002300880.1 CDS HPP12_0241 NC_011498.1 248630 249025 R hypothetical protein complement(248630..249025) Helicobacter pylori P12 7010612 YP_002300881.1 CDS HPP12_0242 NC_011498.1 249018 249302 R hypothetical protein complement(249018..249302) Helicobacter pylori P12 7010613 YP_002300882.1 CDS napA NC_011498.1 249323 249757 R neutrophil-activating protein A complement(249323..249757) Helicobacter pylori P12 7010614 YP_002300883.1 CDS HPP12_0244 NC_011498.1 249963 251108 R histidine kinase sensor protein complement(249963..251108) Helicobacter pylori P12 7010615 YP_002300884.1 CDS HPP12_0245 NC_011498.1 251105 251422 R hypothetical protein complement(251105..251422) Helicobacter pylori P12 7010616 YP_002300885.1 CDS flgI NC_011498.1 251419 252447 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(251419..252447) Helicobacter pylori P12 7010617 YP_002300886.1 CDS deaD NC_011498.1 252636 254114 D ATP-dependent RNA helicase 252636..254114 Helicobacter pylori P12 7010618 YP_002300887.1 CDS HPP12_0248 NC_011498.1 254135 255223 D spfH domain-containing protein 254135..255223 Helicobacter pylori P12 7010619 YP_002300888.1 CDS HPP12_0249 NC_011498.1 255230 255769 D hypothetical protein 255230..255769 Helicobacter pylori P12 7010620 YP_002300889.1 CDS HPP12_0250 NC_011498.1 255818 257368 R ATPase protein; oligopeptide permease complement(255818..257368) Helicobacter pylori P12 7010621 YP_002300890.1 CDS hopF NC_011498.1 258741 260204 D outer membrane protein HopF 258741..260204 Helicobacter pylori P12 7010624 YP_002300891.1 CDS hopG NC_011498.1 260217 261629 D outer membrane protein HopG 260217..261629 Helicobacter pylori P12 7010625 YP_002300892.1 CDS purA NC_011498.1 261727 262962 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 261727..262962 Helicobacter pylori P12 7010626 YP_002300893.1 CDS HPP12_0255 NC_011498.1 262959 263387 D hypothetical protein 262959..263387 Helicobacter pylori P12 7010627 YP_002300894.1 CDS HPP12_0256 NC_011498.1 263380 264051 D secreted protein 263380..264051 Helicobacter pylori P12 7010628 YP_002300895.1 CDS HPP12_0257 NC_011498.1 264048 265103 D zinc metalloprotease 264048..265103 Helicobacter pylori P12 7010629 YP_002300896.1 CDS xseA NC_011498.1 265116 266378 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 265116..266378 Helicobacter pylori P12 7010630 YP_002300897.1 CDS mod-1 NC_011498.1 266397 267569 R type III R-M system methyltransferase complement(266397..267569) Helicobacter pylori P12 7010631 YP_002300898.1 CDS HPP12_0260 NC_011498.1 267562 267804 R hypothetical protein complement(267562..267804) Helicobacter pylori P12 7010632 YP_002300899.1 CDS HPP12_0261 NC_011498.1 267921 268562 D type II R-M system restriction endonuclease 267921..268562 Helicobacter pylori P12 7010633 YP_002300900.1 CDS hpaim NC_011498.1 268652 269410 D type II R-M system methyltransferase 268652..269410 Helicobacter pylori P12 7010634 YP_002300901.1 CDS clpB NC_011498.1 269483 272053 D heat shock protein; ATP-dependent protease binding subunit 269483..272053 Helicobacter pylori P12 7010635 YP_002300902.1 CDS ccdA NC_011498.1 272110 272829 D cytochrome C-type biogenesis protein CcdA 272110..272829 Helicobacter pylori P12 7010636 YP_002300903.1 CDS pyrC-1 NC_011498.1 272839 273975 D dihydroorotase 272839..273975 Helicobacter pylori P12 7010637 YP_002300904.1 CDS HPP12_0266 NC_011498.1 273960 275189 D Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 273960..275189 Helicobacter pylori P12 7010638 YP_002300905.1 CDS HPP12_0267 NC_011498.1 275250 275492 D hypothetical protein 275250..275492 Helicobacter pylori P12 7010639 YP_002300906.1 CDS HPP12_0268 NC_011498.1 275502 276815 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 275502..276815 Helicobacter pylori P12 7010640 YP_002300907.1 CDS HPP12_0269 NC_011498.1 276854 277507 D hypothetical protein 276854..277507 Helicobacter pylori P12 7010641 YP_002300908.1 CDS HPP12_0270 NC_011498.1 277500 278483 D hypothetical protein 277500..278483 Helicobacter pylori P12 7010642 YP_002300909.1 CDS HPP12_0271 NC_011498.1 278473 279006 D hypothetical protein 278473..279006 Helicobacter pylori P12 7010643 YP_002300910.1 CDS HPP12_0272 NC_011498.1 279003 279542 D hypothetical protein 279003..279542 Helicobacter pylori P12 7010644 YP_002300911.1 CDS HPP12_0273 NC_011498.1 279558 279956 D hypothetical protein 279558..279956 Helicobacter pylori P12 7010645 YP_002300912.1 CDS HPP12_0274 NC_011498.1 279993 281288 D ATP-dependent nuclease 279993..281288 Helicobacter pylori P12 7010646 YP_002300913.1 CDS HPP12_0275 NC_011498.1 281276 281833 D indole-3-glycerol phosphate synthase 281276..281833 Helicobacter pylori P12 7010647 YP_002300914.1 CDS HPP12_0276 NC_011498.1 281890 282144 D ferredoxin 281890..282144 Helicobacter pylori P12 7010648 YP_002300915.1 CDS HPP12_0277 NC_011498.1 282154 283608 D guanosine pentaphosphate phosphohydrolase 282154..283608 Helicobacter pylori P12 7010649 YP_002300916.1 CDS HPP12_0278 NC_011498.1 283605 284627 D lipopolysaccharide heptosyltransferase-1 283605..284627 Helicobacter pylori P12 7010650 YP_002300917.1 CDS HPP12_0279 NC_011498.1 284624 285610 D acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 284624..285610 Helicobacter pylori P12 7010651 YP_002300918.1 CDS tgt NC_011498.1 285868 286983 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(285868..286983) Helicobacter pylori P12 7010652 YP_002300919.1 CDS HPP12_0281 NC_011498.1 287040 288476 D hypothetical protein 287040..288476 Helicobacter pylori P12 7010653 YP_002300920.1 CDS aroB NC_011498.1 288481 289512 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 288481..289512 Helicobacter pylori P12 7010654 YP_002300921.1 CDS HPP12_0283 NC_011498.1 289503 291074 D mechanosensitive ion channel protein 289503..291074 Helicobacter pylori P12 7010655 YP_002300922.1 CDS HPP12_0284 NC_011498.1 291071 292327 D miaB-like tRNA modifying enzyme 291071..292327 Helicobacter pylori P12 7010656 YP_002300923.1 CDS ftsH-1 NC_011498.1 292314 293966 D metalloprotease; cell division protein FtsH 292314..293966 Helicobacter pylori P12 7010657 YP_002300924.1 CDS HPP12_0286 NC_011498.1 293969 294487 D hypothetical protein 293969..294487 Helicobacter pylori P12 7010658 YP_002300925.1 CDS HPP12_0287 NC_011498.1 294500 294973 D hypothetical protein 294500..294973 Helicobacter pylori P12 7010659 YP_002300926.1 CDS HPP12_0288 NC_011498.1 295040 303760 D vacuolating cytotoxin VacA-like protein 295040..303760 Helicobacter pylori P12 7010660 YP_002300927.1 CDS lysA NC_011498.1 303808 305025 D diaminopimelate decarboxylase 303808..305025 Helicobacter pylori P12 7010661 YP_002300928.1 CDS HPP12_0290 NC_011498.1 305030 305320 D chorismate mutase 305030..305320 Helicobacter pylori P12 7010662 YP_002300929.1 CDS HPP12_0291 NC_011498.1 305333 306205 D hypothetical protein 305333..306205 Helicobacter pylori P12 7010663 YP_002300930.1 CDS pabB NC_011498.1 306206 307885 D para-aminobenzoate PabA-synthetase 306206..307885 Helicobacter pylori P12 7010664 YP_002300931.1 CDS amiE NC_011498.1 308078 309097 D aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 308078..309097 Helicobacter pylori P12 7010665 YP_002300932.1 CDS flgL NC_011498.1 309193 311679 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL complement(309193..311679) Helicobacter pylori P12 7010666 YP_002300933.1 CDS rplU NC_011498.1 311923 312237 D 50S ribosomal protein L21 311923..312237 Helicobacter pylori P12 7010667 YP_002300934.1 CDS rpmA NC_011498.1 312251 312517 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 312251..312517 Helicobacter pylori P12 7010668 YP_002300935.1 CDS dppA NC_011498.1 312634 314286 D periplasmic dipeptide-binding protein 312634..314286 Helicobacter pylori P12 7010669 YP_002300936.1 CDS dppB NC_011498.1 314297 315301 D dipeptide transport system permease protein 314297..315301 Helicobacter pylori P12 7010670 YP_002300937.1 CDS dppC NC_011498.1 315301 316158 D dipeptide transport system permease protein 315301..316158 Helicobacter pylori P12 7010671 YP_002300938.1 CDS dppD NC_011498.1 316170 317033 D dipeptide ABC transporter 316170..317033 Helicobacter pylori P12 7010672 YP_002300939.1 CDS dppF NC_011498.1 317030 317836 D dipeptide ABC transporter 317030..317836 Helicobacter pylori P12 7010673 YP_002300940.1 CDS obgE NC_011498.1 317856 318938 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 317856..318938 Helicobacter pylori P12 7010674 YP_002300941.1 CDS HPP12_0303 NC_011498.1 319120 320115 D hypothetical protein 319120..320115 Helicobacter pylori P12 7010675 YP_002300942.1 CDS HPP12_0304 NC_011498.1 320355 320909 D hypothetical protein 320355..320909 Helicobacter pylori P12 7010676 YP_002300943.1 CDS hemL NC_011498.1 320919 322211 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 320919..322211 Helicobacter pylori P12 7010677 YP_002300944.1 CDS HPP12_0306 NC_011498.1 322217 322480 D hypothetical protein 322217..322480 Helicobacter pylori P12 7010678 YP_002300945.1 CDS HPP12_0307 NC_011498.1 322496 322900 D hypothetical protein 322496..322900 Helicobacter pylori P12 7010679 YP_002300946.1 CDS HPP12_0308 NC_011498.1 322984 323868 D N-carbamoyl-D-amino acid amidohydrolase 322984..323868 Helicobacter pylori P12 7010680 YP_002300947.1 CDS HPP12_0309 NC_011498.1 323881 324762 D polysaccharide deacetylase 323881..324762 Helicobacter pylori P12 7010681 YP_002300948.1 CDS HPP12_0310 NC_011498.1 324808 325167 D hypothetical protein 324808..325167 Helicobacter pylori P12 7010682 YP_002300949.1 CDS HPP12_0311 NC_011498.1 325167 326132 D ATP/GTP binding protein 325167..326132 Helicobacter pylori P12 7010683 YP_002300950.1 CDS HPP12_0312 NC_011498.1 326138 327283 R nitrite extrusion protein complement(326138..327283) Helicobacter pylori P12 7010684 YP_002300951.1 CDS HPP12_0313 NC_011498.1 327382 327546 R hypothetical protein complement(327382..327546) Helicobacter pylori P12 7010685 YP_002300952.1 CDS HPP12_0315 NC_011498.1 330588 331343 R heme iron utilization protein complement(330588..331343) Helicobacter pylori P12 7010687 YP_002300953.1 CDS argS NC_011498.1 331404 333029 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(331404..333029) Helicobacter pylori P12 7010688 YP_002300954.1 CDS tatA NC_011498.1 333032 333271 R sec-independent protein translocase protein complement(333032..333271) Helicobacter pylori P12 7010689 YP_002300955.1 CDS gmk NC_011498.1 333341 333961 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(333341..333961) Helicobacter pylori P12 7010690 YP_002300956.1 CDS HPP12_0319 NC_011498.1 333954 335444 R poly E-rich protein complement(333954..335444) Helicobacter pylori P12 7010691 YP_002300957.1 CDS HPP12_0320 NC_011498.1 335587 336129 D membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT 335587..336129 Helicobacter pylori P12 7010692 YP_002300958.1 CDS horC NC_011498.1 336138 336902 R outer membrane protein HorC complement(336138..336902) Helicobacter pylori P12 7010693 YP_002300959.1 CDS flgH NC_011498.1 337007 337720 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 337007..337720 Helicobacter pylori P12 7010694 YP_002300960.1 CDS HPP12_0323 NC_011498.1 337738 338427 D CMP-N-acetylneuraminic acid synthetase 337738..338427 Helicobacter pylori P12 7010695 YP_002300961.1 CDS HPP12_0324 NC_011498.1 338418 339290 D CMP-N-acetylneuraminic acid synthetase 338418..339290 Helicobacter pylori P12 7010696 YP_002300962.1 CDS flaG-1 NC_011498.1 339287 339829 D flagellar biosynthesis protein G 339287..339829 Helicobacter pylori P12 7010697 YP_002300963.1 CDS lpxK NC_011498.1 339762 340700 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(339762..340700) Helicobacter pylori P12 7010698 YP_002300964.1 CDS nadE NC_011498.1 340697 341479 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(340697..341479) Helicobacter pylori P12 7010699 YP_002723858.1 CDS ilvC NC_011498.1 341728 342720 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 341728..342720 Helicobacter pylori P12 7565104 YP_002300965.1 CDS minD NC_011498.1 342744 343550 D MinD cell division inhibitor protein 342744..343550 Helicobacter pylori P12 7010701 YP_002300966.1 CDS minE NC_011498.1 343547 343780 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 343547..343780 Helicobacter pylori P12 7010702 YP_002300967.1 CDS dprA NC_011498.1 343787 344587 D DNA processing protein 343787..344587 Helicobacter pylori P12 7010703 YP_002300968.1 CDS HPP12_0331 NC_011498.1 344584 344988 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 344584..344988 Helicobacter pylori P12 7010704 YP_002300969.1 CDS hcpH NC_011498.1 345121 345888 D cysteine-rich protein H 345121..345888 Helicobacter pylori P12 7010705 YP_002300970.1 CDS HPP12_0333 NC_011498.1 346075 346413 D hypothetical protein 346075..346413 Helicobacter pylori P12 7010706 YP_002300971.1 CDS HPP12_0334 NC_011498.1 346397 346957 D hypothetical protein 346397..346957 Helicobacter pylori P12 7010707 YP_002300972.1 CDS HPP12_0335 NC_011498.1 346987 347388 D lysozyme-like protein 346987..347388 Helicobacter pylori P12 7010708 YP_002300973.1 CDS HPP12_0336 NC_011498.1 347376 347642 D hypothetical protein 347376..347642 Helicobacter pylori P12 7010709 YP_002300974.1 CDS HPP12_0337 NC_011498.1 348032 348328 D hypothetical protein 348032..348328 Helicobacter pylori P12 7010710 YP_002300975.1 CDS HPP12_0338 NC_011498.1 348477 349109 D hypothetical protein 348477..349109 Helicobacter pylori P12 7010711 YP_002300976.1 CDS HPP12_0339 NC_011498.1 349093 349287 D hypothetical protein 349093..349287 Helicobacter pylori P12 7010712 YP_002300977.1 CDS HPP12_0340 NC_011498.1 349463 350266 D hypothetical protein 349463..350266 Helicobacter pylori P12 7010713 YP_002300978.1 CDS HPP12_0341 NC_011498.1 350284 351177 R pseudouridine synthase D complement(350284..351177) Helicobacter pylori P12 7010714 YP_002300979.1 CDS recJ NC_011498.1 351177 352727 R single-stranded-DNA-specific exonuclease complement(351177..352727) Helicobacter pylori P12 7010715 YP_002300980.1 CDS pyrG NC_011498.1 352736 354352 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(352736..354352) Helicobacter pylori P12 7010716 YP_002300981.1 CDS HPP12_0344 NC_011498.1 354612 355274 D hypothetical protein 354612..355274 Helicobacter pylori P12 7010717 YP_002300982.1 CDS fliF NC_011498.1 355318 357021 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 355318..357021 Helicobacter pylori P12 7010718 YP_002300983.1 CDS fliG NC_011498.1 357039 358070 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 357039..358070 Helicobacter pylori P12 7010719 YP_002300984.1 CDS fliH NC_011498.1 358057 358833 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 358057..358833 Helicobacter pylori P12 7010720 YP_002300985.1 CDS dxs NC_011498.1 358836 360686 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 358836..360686 Helicobacter pylori P12 7010721 YP_002300986.1 CDS lepA NC_011498.1 360683 362497 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 360683..362497 Helicobacter pylori P12 7010722 YP_002300987.1 CDS HPP12_0350 NC_011498.1 362555 363268 D hypothetical protein 362555..363268 Helicobacter pylori P12 7010723 YP_002300988.1 CDS HPP12_0351 NC_011498.1 363211 363507 D hypothetical protein 363211..363507 Helicobacter pylori P12 7010724 YP_002300989.1 CDS flgG-1 NC_011498.1 364187 364996 R flagellar basal-body rod protein complement(364187..364996) Helicobacter pylori P12 7010725 YP_002300990.1 CDS kgtP NC_011498.1 365050 366336 R alpha-ketoglutarate permease complement(365050..366336) Helicobacter pylori P12 7010726 YP_002300991.1 CDS ftsK NC_011498.1 366596 369187 R cell division protein FtsK complement(366596..369187) Helicobacter pylori P12 7010727 YP_002300992.1 CDS HPP12_0355 NC_011498.1 369184 371520 R hypothetical protein complement(369184..371520) Helicobacter pylori P12 7010728 YP_002300993.1 CDS tktA NC_011498.1 371517 373442 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(371517..373442) Helicobacter pylori P12 7010729 YP_002300994.1 CDS HPP12_0357 NC_011498.1 373489 374331 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(373489..374331) Helicobacter pylori P12 7010730 YP_002300995.1 CDS HPP12_0358 NC_011498.1 374297 375004 R hemolysin complement(374297..375004) Helicobacter pylori P12 7010731 YP_002300996.1 CDS HPP12_0359 NC_011498.1 375004 375519 R hypothetical protein complement(375004..375519) Helicobacter pylori P12 7010732 YP_002300997.1 CDS pyrB NC_011498.1 375586 376509 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 375586..376509 Helicobacter pylori P12 7010733 YP_002300998.1 CDS hofB NC_011498.1 376764 378203 D outer membrane protein HofB 376764..378203 Helicobacter pylori P12 7010734 YP_002300999.1 CDS msbA NC_011498.1 378294 379949 D multidrug resistance protein 378294..379949 Helicobacter pylori P12 7010735 YP_002301000.1 CDS HPP12_0363 NC_011498.1 379943 380566 D hypothetical protein 379943..380566 Helicobacter pylori P12 7010736 YP_002301001.1 CDS HPP12_0364 NC_011498.1 380570 381139 D integral membrane protein 380570..381139 Helicobacter pylori P12 7010737 YP_002301002.1 CDS HPP12_0365 NC_011498.1 381250 382394 D hypothetical protein join(381250..381654,381654..382394) Helicobacter pylori P12 7010738 YP_002301003.1 CDS HPP12_0366 NC_011498.1 382387 383088 D hypothetical protein 382387..383088 Helicobacter pylori P12 7010739 YP_002301004.1 CDS nixA NC_011498.1 383146 384141 D high-affinity nickel transport protein 383146..384141 Helicobacter pylori P12 7010740 YP_002301005.1 CDS HPP12_0368 NC_011498.1 384145 384660 R hypothetical protein complement(384145..384660) Helicobacter pylori P12 7010741 YP_002301006.1 CDS HPP12_0369 NC_011498.1 384797 386113 D secreted protein 384797..386113 Helicobacter pylori P12 7010742 YP_002301007.1 CDS HPP12_0370 NC_011498.1 386321 386536 R hypothetical protein complement(386321..386536) Helicobacter pylori P12 7010743 YP_002301008.1 CDS copP NC_011498.1 386770 386970 R copper ion binding protein complement(386770..386970) Helicobacter pylori P12 7010744 YP_002301009.1 CDS copA NC_011498.1 386971 389196 R copper-transporting ATPase complement(386971..389196) Helicobacter pylori P12 7010745 YP_002301010.1 CDS pssA NC_011498.1 389193 389906 R phosphatidylserine synthase complement(389193..389906) Helicobacter pylori P12 7010746 YP_002301011.1 CDS HPP12_0374 NC_011498.1 389896 390150 R hypothetical protein complement(389896..390150) Helicobacter pylori P12 7010747 YP_002301012.1 CDS ftsH-2 NC_011498.1 390153 392051 R metalloprotease; cell division protein FtsH complement(390153..392051) Helicobacter pylori P12 7010748 YP_002301013.1 CDS prmA NC_011498.1 392069 393058 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase complement(392069..393058) Helicobacter pylori P12 7010749 YP_002301014.1 CDS cheY NC_011498.1 393059 393433 R chemotaxis protein complement(393059..393433) Helicobacter pylori P12 7010750 YP_002301015.1 CDS horD NC_011498.1 393723 394325 D outer membrane protein HorD 393723..394325 Helicobacter pylori P12 7010751 YP_002301016.1 CDS HPP12_0379 NC_011498.1 394489 394896 R hypothetical protein complement(394489..394896) Helicobacter pylori P12 7010753 YP_002301017.1 CDS HPP12_0380 NC_011498.1 394899 395141 R hypothetical protein complement(394899..395141) Helicobacter pylori P12 7010754 YP_002301018.1 CDS gidB NC_011498.1 395135 395671 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(395135..395671) Helicobacter pylori P12 7010755 YP_002301019.1 CDS queA NC_011498.1 395668 396705 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(395668..396705) Helicobacter pylori P12 7010756 YP_002301020.1 CDS tatB NC_011498.1 396706 397467 R sec-independent protein translocase subunit complement(396706..397467) Helicobacter pylori P12 7010757 YP_002301021.1 CDS tatC NC_011498.1 397460 397942 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(397460..397942) Helicobacter pylori P12 7010758 YP_002301022.1 CDS ruvB NC_011498.1 398010 399020 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(398010..399020) Helicobacter pylori P12 7010759 YP_002301023.1 CDS panB NC_011498.1 399021 399833 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(399021..399833) Helicobacter pylori P12 7010760 YP_002301024.1 CDS HPP12_0387 NC_011498.1 399982 400704 D hypothetical protein 399982..400704 Helicobacter pylori P12 7010761 YP_002301025.1 CDS HPP12_0388 NC_011498.1 400694 401551 D hypothetical protein 400694..401551 Helicobacter pylori P12 7010762 YP_002301026.1 CDS HPP12_0389 NC_011498.1 401560 402504 D hypothetical protein 401560..402504 Helicobacter pylori P12 7010763 YP_002301027.1 CDS HPP12_0390 NC_011498.1 402514 403836 D metalloendopeptidase related membrane protein 402514..403836 Helicobacter pylori P12 7010764 YP_002301028.1 CDS minC NC_011498.1 403839 404426 D blocks the formation of polar Z-ring septums; septum formation inhibitor 403839..404426 Helicobacter pylori P12 7010765 YP_002301029.1 CDS lpxC NC_011498.1 404423 405310 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 404423..405310 Helicobacter pylori P12 7010766 YP_002301030.1 CDS HPP12_0393 NC_011498.1 405332 405805 D hypothetical protein 405332..405805 Helicobacter pylori P12 7010767 YP_002301031.1 CDS thrB NC_011498.1 405859 406740 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 405859..406740 Helicobacter pylori P12 7010768 YP_002301032.1 CDS HPP12_0395 NC_011498.1 406712 406981 D hypothetical protein 406712..406981 Helicobacter pylori P12 7010769 YP_002301033.1 CDS infB NC_011498.1 406978 409821 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 406978..409821 Helicobacter pylori P12 7010770 YP_002301034.1 CDS rbfA NC_011498.1 409821 410156 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 409821..410156 Helicobacter pylori P12 7010771 YP_002301035.1 CDS HPP12_0398 NC_011498.1 410149 410589 D hypothetical protein 410149..410589 Helicobacter pylori P12 7010772 YP_002301036.1 CDS HPP12_0399 NC_011498.1 410697 412685 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(410697..412685) Helicobacter pylori P12 7010773 YP_002301037.1 CDS HPP12_0400 NC_011498.1 412884 413996 D integral membrane protein; phosphodiesterase domain-containing protein 412884..413996 Helicobacter pylori P12 7010774 YP_002301038.1 CDS HPP12_0401 NC_011498.1 414374 415045 D transcriptional regulator 414374..415045 Helicobacter pylori P12 7010775 YP_002301039.1 CDS HPP12_0402 NC_011498.1 415561 416604 R hypothetical protein complement(415561..416604) Helicobacter pylori P12 7010776 YP_002301040.1 CDS flhA NC_011498.1 416635 418836 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(416635..418836) Helicobacter pylori P12 7010777 YP_002301041.1 CDS rpsO NC_011498.1 418976 419248 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 418976..419248 Helicobacter pylori P12 7010778 YP_002301042.1 CDS HPP12_0405 NC_011498.1 419278 420567 D hypothetical protein 419278..420567 Helicobacter pylori P12 7010779 YP_002301043.1 CDS HPP12_0406 NC_011498.1 420696 421199 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 420696..421199 Helicobacter pylori P12 7010780 YP_002301044.1 CDS HPP12_0407 NC_011498.1 421213 422286 D proline peptidase 421213..422286 Helicobacter pylori P12 7010781 YP_002301045.1 CDS folK NC_011498.1 422283 422774 D 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokina se 422283..422774 Helicobacter pylori P12 7010782 YP_002301046.1 CDS flhF NC_011498.1 422771 424147 D positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 422771..424147 Helicobacter pylori P12 7010783 YP_002301047.1 CDS HPP12_0410 NC_011498.1 424144 425028 D ATP-binding protein 424144..425028 Helicobacter pylori P12 7010784 YP_002301048.1 CDS HPP12_0411 NC_011498.1 425033 425347 D hypothetical protein 425033..425347 Helicobacter pylori P12 7010785 YP_002301049.1 CDS fliA NC_011498.1 425325 426092 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 425325..426092 Helicobacter pylori P12 7010786 YP_002301050.1 CDS fliM NC_011498.1 426085 427149 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 426085..427149 Helicobacter pylori P12 7010787 YP_002301051.1 CDS fliY NC_011498.1 427153 428016 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY 427153..428016 Helicobacter pylori P12 7010788 YP_002301052.1 CDS HPP12_0415 NC_011498.1 428045 428581 D hypothetical protein 428045..428581 Helicobacter pylori P12 7010789 YP_002301053.1 CDS HPP12_0416 NC_011498.1 428578 429075 D hypothetical protein 428578..429075 Helicobacter pylori P12 7010790 YP_002301054.1 CDS fur NC_011498.1 429095 429547 R ferric uptake regulation protein complement(429095..429547) Helicobacter pylori P12 7010791 YP_002301055.1 CDS rarA NC_011498.1 429707 430882 R recombination factor protein RarA complement(429707..430882) Helicobacter pylori P12 7010792 YP_002301056.1 CDS hspR NC_011498.1 430879 431250 R transcriptional activator of heat-shock proteins complement(430879..431250) Helicobacter pylori P12 7010793 YP_002301057.1 CDS HPP12_0420 NC_011498.1 431260 432126 R CO-chaperone-curved DNA binding protein A complement(431260..432126) Helicobacter pylori P12 7010794 YP_002301058.1 CDS HPP12_0421 NC_011498.1 432294 433544 D hypothetical protein 432294..433544 Helicobacter pylori P12 7010795 YP_002301059.1 CDS HPP12_0422 NC_011498.1 433652 434488 R DNA-polymerase I-like 5'-3' exonuclease complement(433652..434488) Helicobacter pylori P12 7010796 YP_002301060.1 CDS HPP12_0423 NC_011498.1 434743 435639 R two component response regulator complement(434743..435639) Helicobacter pylori P12 7010797 YP_002301061.1 CDS ispDF NC_011498.1 435661 436881 R bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein complement(435661..436881) Helicobacter pylori P12 7010798 YP_002301062.1 CDS HPP12_0425 NC_011498.1 436903 438333 R serine protease complement(436903..438333) Helicobacter pylori P12 7010799 YP_002301063.1 CDS HPP12_0426 NC_011498.1 438378 439820 R amino acid permease complement(438378..439820) Helicobacter pylori P12 7010800 YP_002301064.1 CDS pgsA NC_011498.1 440034 440636 R phosphatidylglycerophosphate synthase complement(440034..440636) Helicobacter pylori P12 7010801 YP_002301065.1 CDS HPP12_0428 NC_011498.1 440570 441178 R hypothetical protein complement(440570..441178) Helicobacter pylori P12 7010802 YP_002301066.1 CDS HPP12_0429 NC_011498.1 441188 441976 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(441188..441976) Helicobacter pylori P12 7010803 YP_002301067.1 CDS dapA NC_011498.1 441973 442875 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(441973..442875) Helicobacter pylori P12 7010804 YP_002301068.1 CDS HPP12_0431 NC_011498.1 442890 444224 R zinc protease complement(442890..444224) Helicobacter pylori P12 7010805 YP_002301069.1 CDS pyrD NC_011498.1 444221 445276 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(444221..445276) Helicobacter pylori P12 7010806 YP_002301070.1 CDS ppk NC_011498.1 445315 447342 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(445315..447342) Helicobacter pylori P12 7010807 YP_002301071.1 CDS hsdS-1 NC_011498.1 448002 449183 R type I R-M system S protein complement(448002..449183) Helicobacter pylori P12 7010809 YP_002301072.1 CDS hsdM-1 NC_011498.1 449176 450807 R type I R-M system M protein complement(449176..450807) Helicobacter pylori P12 7010810 YP_002301073.1 CDS HPP12_0437 NC_011498.1 452423 453496 D integrase/recombinase XercD family 452423..453496 Helicobacter pylori P12 7010812 YP_002301074.1 CDS HPP12_0438 NC_011498.1 453578 454261 R hypothetical protein complement(453578..454261) Helicobacter pylori P12 7010813 YP_002301075.1 CDS virb6 NC_011498.1 454334 455632 R VirB6 type IV secretion protein complement(454334..455632) Helicobacter pylori P12 7010814 YP_002301076.1 CDS HPP12_0440 NC_011498.1 455598 455876 R hypothetical protein complement(455598..455876) Helicobacter pylori P12 7010815 YP_002301077.1 CDS HPP12_0441 NC_011498.1 455928 457328 R hypothetical protein complement(455928..457328) Helicobacter pylori P12 7010816 YP_002301078.1 CDS HPP12_0442 NC_011498.1 457332 457577 R hypothetical protein complement(457332..457577) Helicobacter pylori P12 7010817 YP_002301079.1 CDS HPP12_0443 NC_011498.1 457791 459272 R hypothetical protein complement(457791..459272) Helicobacter pylori P12 7010818 YP_002301080.1 CDS HPP12_0444 NC_011498.1 459405 460469 R hypothetical protein complement(459405..460469) Helicobacter pylori P12 7010819 YP_002301081.1 CDS HPP12_0445 NC_011498.1 460312 460803 R hypothetical protein complement(460312..460803) Helicobacter pylori P12 7010820 YP_002301082.1 CDS HPP12_0446 NC_011498.1 460810 461832 R hypothetical protein complement(460810..461832) Helicobacter pylori P12 7010821 YP_002301083.1 CDS HPP12_0447 NC_011498.1 462096 470522 D DNA methylase 462096..470522 Helicobacter pylori P12 7010822 YP_002301084.1 CDS parA NC_011498.1 470785 471441 D chromosome partitioning protein 470785..471441 Helicobacter pylori P12 7010823 YP_002301085.1 CDS HPP12_0449 NC_011498.1 471523 471807 D hypothetical protein 471523..471807 Helicobacter pylori P12 7010824 YP_002301086.1 CDS HPP12_0450 NC_011498.1 471839 473017 D hypothetical protein 471839..473017 Helicobacter pylori P12 7010825 YP_002301087.1 CDS virD2-1 NC_011498.1 473042 474955 R relaxase complement(473042..474955) Helicobacter pylori P12 7010826 YP_002301088.1 CDS HPP12_0452 NC_011498.1 475253 475567 D hypothetical protein 475253..475567 Helicobacter pylori P12 7010827 YP_002301089.1 CDS HPP12_0453 NC_011498.1 475560 475841 D hypothetical protein 475560..475841 Helicobacter pylori P12 7010828 YP_002301090.1 CDS virD4-1 NC_011498.1 476105 477832 R VirD4 coupling protein complement(476105..477832) Helicobacter pylori P12 7010829 YP_002301091.1 CDS HPP12_0455 NC_011498.1 477879 478391 R hypothetical protein complement(477879..478391) Helicobacter pylori P12 7010830 YP_002301092.1 CDS HPP12_0456 NC_011498.1 478392 478682 R hypothetical protein complement(478392..478682) Helicobacter pylori P12 7010831 YP_002301093.1 CDS HPP12_0457 NC_011498.1 478679 479134 R hypothetical protein complement(478679..479134) Helicobacter pylori P12 7010832 YP_002301094.1 CDS virB11-1 NC_011498.1 479131 480072 R VirB11 type IV secretion ATPase complement(479131..480072) Helicobacter pylori P12 7010833 YP_002301095.1 CDS HPP12_0459 NC_011498.1 480072 480371 R hypothetical protein complement(480072..480371) Helicobacter pylori P12 7010834 YP_002301096.1 CDS HPP12_0460 NC_011498.1 480368 480631 R hypothetical protein complement(480368..480631) Helicobacter pylori P12 7010835 YP_002301097.1 CDS HPP12_0461 NC_011498.1 480624 480917 R hypothetical protein complement(480624..480917) Helicobacter pylori P12 7010836 YP_002301098.1 CDS virB10-1 NC_011498.1 480987 482252 R VirB10 type IV secretion protein complement(480987..482252) Helicobacter pylori P12 7010837 YP_002301099.1 CDS virB9-1 NC_011498.1 482252 483784 R VirB9 type IV secretion protein complement(482252..483784) Helicobacter pylori P12 7010838 YP_002301100.1 CDS virB8-1 NC_011498.1 483784 484953 R VirB8 type IV secretion protein complement(483784..484953) Helicobacter pylori P12 7010839 YP_002301101.1 CDS virB7-1 NC_011498.1 484957 485073 R VirB7 type IV secretion protein complement(484957..485073) Helicobacter pylori P12 7010840 YP_002301102.1 CDS virB3-1 NC_011498.1 489522 489788 R VirB3 type IV secretion protein complement(489522..489788) Helicobacter pylori P12 7010843 YP_002301103.1 CDS virB2-1 NC_011498.1 489789 490091 R VirB2 type IV secretion protein complement(489789..490091) Helicobacter pylori P12 7010844 YP_002301104.1 CDS HPP12_0470 NC_011498.1 490088 490372 R hypothetical protein complement(490088..490372) Helicobacter pylori P12 7010845 YP_002301105.1 CDS HPP12_0471 NC_011498.1 490433 491611 R hypothetical protein complement(490433..491611) Helicobacter pylori P12 7010846 YP_002301106.1 CDS HPP12_0472 NC_011498.1 491618 491911 R hypothetical protein complement(491618..491911) Helicobacter pylori P12 7010847 YP_002301107.1 CDS HPP12_0473 NC_011498.1 491931 492710 R hypothetical protein complement(491931..492710) Helicobacter pylori P12 7010848 YP_002301108.1 CDS HPP12_0474 NC_011498.1 494743 496638 R hypothetical protein complement(494743..496638) Helicobacter pylori P12 7010849 YP_002301109.1 CDS HPP12_0475 NC_011498.1 496664 497431 R hypothetical protein complement(496664..497431) Helicobacter pylori P12 7010850 YP_002301110.1 CDS HPP12_0476 NC_011498.1 497441 497791 R integral membrane protein complement(497441..497791) Helicobacter pylori P12 7010851 YP_002301111.1 CDS HPP12_0477 NC_011498.1 497757 499244 R hypothetical protein complement(497757..499244) Helicobacter pylori P12 7010852 YP_002301112.1 CDS HPP12_0478 NC_011498.1 499256 499744 R hypothetical protein complement(499256..499744) Helicobacter pylori P12 7010853 YP_002301113.1 CDS pepF NC_011498.1 499729 501465 R oligoendopeptidase F complement(499729..501465) Helicobacter pylori P12 7010854 YP_002301114.1 CDS kefB NC_011498.1 501563 502813 R glutathione-regulated potassium-efflux system protein complement(501563..502813) Helicobacter pylori P12 7010855 YP_002301115.1 CDS horE NC_011498.1 503132 503692 R outer membrane protein HorE complement(503132..503692) Helicobacter pylori P12 7010856 YP_002301116.1 CDS HPP12_0482 NC_011498.1 503736 503897 R hypothetical protein complement(503736..503897) Helicobacter pylori P12 7010857 YP_002301117.1 CDS modA NC_011498.1 503916 504656 D molybdenum ABC transporter ModA 503916..504656 Helicobacter pylori P12 7010858 YP_002301118.1 CDS modB NC_011498.1 504678 505352 D molybdenum ABC transporter ModB 504678..505352 Helicobacter pylori P12 7010859 YP_002301119.1 CDS modD NC_011498.1 505349 506146 D molybdenum ABC transporter ModD 505349..506146 Helicobacter pylori P12 7010860 YP_002301120.1 CDS gltX NC_011498.1 506265 507656 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(506265..507656) Helicobacter pylori P12 7010861 YP_002301121.1 CDS hopJ NC_011498.1 507773 508882 D outer membrane protein HopJ 507773..508882 Helicobacter pylori P12 7010862 YP_002301122.1 CDS HPP12_0488 NC_011498.1 508891 510528 D type II R-M system methyltransferase 508891..510528 Helicobacter pylori P12 7010863 YP_002301123.1 CDS HPP12_0489 NC_011498.1 510494 511336 D DD-heptosyltransferase 510494..511336 Helicobacter pylori P12 7010864 YP_002301124.1 CDS typA NC_011498.1 511382 513181 D GTP-binding protein of the TypA subfamily 511382..513181 Helicobacter pylori P12 7010865 YP_002301125.1 CDS HPP12_0491 NC_011498.1 513187 513669 D type II R-M system methyltransferase 513187..513669 Helicobacter pylori P12 7010866 YP_002301126.1 CDS HPP12_0492 NC_011498.1 513767 514711 R catalase like protein complement(513767..514711) Helicobacter pylori P12 7010867 YP_002301127.1 CDS hofC NC_011498.1 514988 516574 D outer membrane protein HofC 514988..516574 Helicobacter pylori P12 7010868 YP_002301128.1 CDS hofD NC_011498.1 516601 518046 D outer membrane protein HofD 516601..518046 Helicobacter pylori P12 7010869 YP_002301129.1 CDS HPP12_0495 NC_011498.1 518445 521207 D hypothetical protein 518445..521207 Helicobacter pylori P12 7010870 YP_002301130.1 CDS HPP12_0496 NC_011498.1 521220 521837 D hypothetical protein 521220..521837 Helicobacter pylori P12 7010871 YP_002301131.1 CDS HPP12_0497 NC_011498.1 521843 521977 D hypothetical protein 521843..521977 Helicobacter pylori P12 7010872 YP_002301132.1 CDS HPP12_0498 NC_011498.1 522350 523486 R potassium channel protein complement(522350..523486) Helicobacter pylori P12 7010873 YP_002301133.1 CDS rpmB NC_011498.1 523669 523857 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(523669..523857) Helicobacter pylori P12 7010874 YP_002301134.1 CDS HPP12_0500 NC_011498.1 523957 524793 R flagellar sheath adhesin complement(523957..524793) Helicobacter pylori P12 7010875 YP_002301135.1 CDS mraY NC_011498.1 524923 525984 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 524923..525984 Helicobacter pylori P12 7010876 YP_002301136.1 CDS murD NC_011498.1 525986 527254 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 525986..527254 Helicobacter pylori P12 7010877 YP_002301137.1 CDS HPP12_0503 NC_011498.1 527251 527511 R hypothetical protein complement(527251..527511) Helicobacter pylori P12 7010878 YP_002301138.1 CDS ybgC NC_011498.1 527501 527902 R thioesterase family protein complement(527501..527902) Helicobacter pylori P12 7010879 YP_002301139.1 CDS HPP12_0505 NC_011498.1 528133 529461 D sodium-and chloride-dependent transporter 528133..529461 Helicobacter pylori P12 7010880 YP_002301140.1 CDS HPP12_0506 NC_011498.1 529472 530800 D sodium-and chloride-dependent transporter 529472..530800 Helicobacter pylori P12 7010881 YP_002301141.1 CDS pldA NC_011498.1 530815 531882 D outer membrane phospholipase A1 precursor 530815..531882 Helicobacter pylori P12 7010882 YP_002301142.1 CDS dnaN NC_011498.1 531938 533062 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 531938..533062 Helicobacter pylori P12 7010883 YP_002301143.1 CDS gyrB NC_011498.1 533075 535396 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 533075..535396 Helicobacter pylori P12 7010884 YP_002301144.1 CDS HPP12_0510 NC_011498.1 535442 536434 D hypothetical protein 535442..536434 Helicobacter pylori P12 7010885 YP_002301145.1 CDS HPP12_0511 NC_011498.1 536421 537176 D hypothetical protein 536421..537176 Helicobacter pylori P12 7010886 YP_002301146.1 CDS HPP12_0512 NC_011498.1 537385 538596 D outer membrane protein 537385..538596 Helicobacter pylori P12 7010887 YP_002301147.1 CDS HPP12_0513 NC_011498.1 538596 539234 D UDP-sugar diphosphatase 538596..539234 Helicobacter pylori P12 7010888 YP_002301148.1 CDS HPP12_0514 NC_011498.1 539245 540594 D plasminogen binding protein 539245..540594 Helicobacter pylori P12 7010889 YP_002301149.1 CDS glcD NC_011498.1 540596 541975 D glycolate oxidase subunit 540596..541975 Helicobacter pylori P12 7010890 YP_002301150.1 CDS dapB NC_011498.1 541997 542761 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 541997..542761 Helicobacter pylori P12 7010891 YP_002301151.1 CDS lpp NC_011498.1 543095 543211 D urease-enhancing factor 543095..543211 Helicobacter pylori P12 7010892 YP_002301152.1 CDS glnA NC_011498.1 543478 544923 R glutamine synthetase complement(543478..544923) Helicobacter pylori P12 7010893 YP_002301153.1 CDS HPP12_0519 NC_011498.1 545061 547148 D hypothetical protein 545061..547148 Helicobacter pylori P12 7010894 YP_002301154.1 CDS rplI NC_011498.1 547211 547660 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 547211..547660 Helicobacter pylori P12 7010895 YP_002301155.1 CDS hslV NC_011498.1 547664 548206 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 547664..548206 Helicobacter pylori P12 7010896 YP_002301156.1 CDS hslU NC_011498.1 548206 549537 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 548206..549537 Helicobacter pylori P12 7010897 YP_002301157.1 CDS era NC_011498.1 549537 550442 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 549537..550442 Helicobacter pylori P12 7010898 YP_002301158.1 CDS HPP12_0524 NC_011498.1 550439 551431 D hypothetical protein 550439..551431 Helicobacter pylori P12 7010899 YP_002301159.1 CDS HPP12_0525 NC_011498.1 551520 552374 R hypothetical protein complement(551520..552374) Helicobacter pylori P12 7010900 YP_002301160.1 CDS HPP12_0526 NC_011498.1 552393 552584 D IS606 transposase B-like fragment; hypothetical protein 552393..552584 Helicobacter pylori P12 7010901 YP_002301161.1 CDS cag1 NC_011498.1 552705 553052 D cagZeta; cag pathogenicity island protein Zeta 552705..553052 Helicobacter pylori P12 7010902 YP_002301162.1 CDS cag2 NC_011498.1 553160 553525 D cagEpsilon; cag pathogenicity island protein Epsilon 553160..553525 Helicobacter pylori P12 7010903 YP_002301163.1 CDS cag3 NC_011498.1 553525 554970 D cagDelta; cag pathogenicity island protein Delta 553525..554970 Helicobacter pylori P12 7010904 YP_002301164.1 CDS cag4 NC_011498.1 554980 555489 D cagGamma; cag pathogenicity island protein Gamma 554980..555489 Helicobacter pylori P12 7010905 YP_002301165.1 CDS cag5 NC_011498.1 555963 558209 R VirD4-like, cagBeta; cag pathogenicity island protein Beta complement(555963..558209) Helicobacter pylori P12 7010906 YP_002301166.1 CDS virB11-2 NC_011498.1 558218 559210 R VirB11-like, cagAlpha; cag pathogenicity island protein Alpha complement(558218..559210) Helicobacter pylori P12 7010907 YP_002301167.1 CDS cagZ NC_011498.1 559215 559814 R cag pathogenicity island protein Z complement(559215..559814) Helicobacter pylori P12 7010908 YP_002301168.1 CDS cagY NC_011498.1 559964 565669 R cag pathogenicity island protein Y VirB10-like protein complement(559964..565669) Helicobacter pylori P12 7010909 YP_002301169.1 CDS cagX NC_011498.1 565684 567252 R cag pathogenicity island protein X VirB9-like protein complement(565684..567252) Helicobacter pylori P12 7010910 YP_002301170.1 CDS cagW NC_011498.1 567305 568912 R cag pathogenicity island protein W complement(567305..568912) Helicobacter pylori P12 7010911 YP_002301171.1 CDS cagV NC_011498.1 568917 569675 R cag pathogenicity island protein V complement(568917..569675) Helicobacter pylori P12 7010912 YP_002301172.1 CDS cagU NC_011498.1 570070 570720 D cag pathogenicity island protein U 570070..570720 Helicobacter pylori P12 7010913 YP_002301173.1 CDS cagT NC_011498.1 570733 571575 D cag pathogenicity island protein T 570733..571575 Helicobacter pylori P12 7010914 YP_002301174.1 CDS cagS NC_011498.1 571777 572376 R cag pathogenicity island protein S complement(571777..572376) Helicobacter pylori P12 7010915 YP_002301175.1 CDS cagQ NC_011498.1 572815 573195 R cag pathogenicity island protein Q complement(572815..573195) Helicobacter pylori P12 7010916 YP_002301176.1 CDS cagR NC_011498.1 572903 573205 D cag pathogenicity island protein R 572903..573205 Helicobacter pylori P12 7010917 YP_002301177.1 CDS cagP NC_011498.1 573621 573974 R cag pathogenicity island protein P complement(573621..573974) Helicobacter pylori P12 7010918 YP_002301178.1 CDS cagM NC_011498.1 574409 575539 D cag pathogenicity island protein M 574409..575539 Helicobacter pylori P12 7010919 YP_002301179.1 CDS cagN NC_011498.1 575554 576474 D cag pathogenicity island protein N 575554..576474 Helicobacter pylori P12 7010920 YP_002301180.1 CDS cagL NC_011498.1 576555 577268 R cag pathogenicity island protein L complement(576555..577268) Helicobacter pylori P12 7010921 YP_002301181.1 CDS cagI NC_011498.1 577265 578410 R cag pathogenicity island protein I complement(577265..578410) Helicobacter pylori P12 7010922 YP_002301182.1 CDS cagH NC_011498.1 578421 579533 R cag pathogenicity island protein H complement(578421..579533) Helicobacter pylori P12 7010923 YP_002301183.1 CDS cagG NC_011498.1 579550 579978 R cag pathogenicity island protein G complement(579550..579978) Helicobacter pylori P12 7010924 YP_002301184.1 CDS cagF NC_011498.1 580037 580843 R cag pathogenicity island protein F complement(580037..580843) Helicobacter pylori P12 7010925 YP_002301185.1 CDS cagE NC_011498.1 580845 583796 R cag pathogenicity island protein E VirB4-like protein complement(580845..583796) Helicobacter pylori P12 7010926 YP_002301186.1 CDS cagD NC_011498.1 583805 584428 R cag pathogenicity island protein D complement(583805..584428) Helicobacter pylori P12 7010927 YP_002301187.1 CDS cagC NC_011498.1 584430 584777 R cag pathogenicity island protein C complement(584430..584777) Helicobacter pylori P12 7010928 YP_002301188.1 CDS cagB NC_011498.1 584923 585150 R cag pathogenicity island protein B complement(584923..585150) Helicobacter pylori P12 7010929 YP_002301189.1 CDS cagA NC_011498.1 585581 589225 D cytotoxin-associated protein A 585581..589225 Helicobacter pylori P12 7010930 YP_002301190.1 CDS HPP12_0556 NC_011498.1 589771 590538 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(589771..590538) Helicobacter pylori P12 7010931 YP_002301191.1 CDS rho NC_011498.1 590577 591893 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(590577..591893) Helicobacter pylori P12 7010932 YP_002301192.1 CDS rpmE NC_011498.1 592159 592362 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 592159..592362 Helicobacter pylori P12 7010933 YP_002301193.1 CDS HPP12_0559 NC_011498.1 592387 593250 D methylase 592387..593250 Helicobacter pylori P12 7010934 YP_002301194.1 CDS HPP12_0560 NC_011498.1 593263 593946 D 23S rRNA methyltransferase 593263..593946 Helicobacter pylori P12 7010935 YP_002301195.1 CDS HPP12_0561 NC_011498.1 593959 594924 D hypothetical protein 593959..594924 Helicobacter pylori P12 7010936 YP_002301196.1 CDS HPP12_0562 NC_011498.1 594921 595742 D hypothetical protein 594921..595742 Helicobacter pylori P12 7010937 YP_002301197.1 CDS HPP12_0563 NC_011498.1 595811 596275 R hypothetical protein complement(595811..596275) Helicobacter pylori P12 7010938 YP_002301198.1 CDS accA NC_011498.1 596710 597648 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(596710..597648) Helicobacter pylori P12 7010939 YP_002301199.1 CDS HPP12_0565 NC_011498.1 597671 598909 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(597671..598909) Helicobacter pylori P12 7010940 YP_002301200.1 CDS acpP NC_011498.1 599012 599248 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(599012..599248) Helicobacter pylori P12 7010941 YP_002301201.1 CDS fabG NC_011498.1 599479 600222 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase complement(599479..600222) Helicobacter pylori P12 7010942 YP_002301202.1 CDS rpsU NC_011498.1 600261 600473 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(600261..600473) Helicobacter pylori P12 7010943 YP_002301203.1 CDS HPP12_0569 NC_011498.1 600574 601824 R hypothetical protein complement(600574..601824) Helicobacter pylori P12 7010944 YP_002301204.1 CDS HPP12_0570 NC_011498.1 601996 602241 D hypothetical protein 601996..602241 Helicobacter pylori P12 7010945 YP_002301205.1 CDS HPP12_0571 NC_011498.1 602265 602912 R hypothetical protein complement(602265..602912) Helicobacter pylori P12 7010946 YP_002301206.1 CDS dapF NC_011498.1 603019 603837 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(603019..603837) Helicobacter pylori P12 7010947 YP_002301207.1 CDS HPP12_0573 NC_011498.1 603952 604998 D outer membrane protein 603952..604998 Helicobacter pylori P12 7010948 YP_002301208.1 CDS HPP12_0574 NC_011498.1 605133 605900 R radical SAM domain-containing protein complement(605133..605900) Helicobacter pylori P12 7010949 YP_002301209.1 CDS HPP12_0575 NC_011498.1 606035 607135 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(606035..607135) Helicobacter pylori P12 7010950 YP_002301210.1 CDS pepA NC_011498.1 607137 608627 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(607137..608627) Helicobacter pylori P12 7010951 YP_002301211.1 CDS HPP12_0577 NC_011498.1 608675 609253 R integral membrane protein complement(608675..609253) Helicobacter pylori P12 7010952 YP_002301212.1 CDS apt NC_011498.1 609268 609807 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(609268..609807) Helicobacter pylori P12 7010953 YP_002301213.1 CDS HPP12_0579 NC_011498.1 609865 610197 R hypothetical protein complement(609865..610197) Helicobacter pylori P12 7010954 YP_002301214.1 CDS rpiB NC_011498.1 610251 610706 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B complement(610251..610706) Helicobacter pylori P12 7010955 YP_002301215.1 CDS HPP12_0581 NC_011498.1 610727 611425 R membrane protein complement(610727..611425) Helicobacter pylori P12 7010956 YP_002301216.1 CDS lepB NC_011498.1 611434 612306 R signal peptidase I complement(611434..612306) Helicobacter pylori P12 7010957 YP_002301217.1 CDS folD NC_011498.1 612307 613179 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(612307..613179) Helicobacter pylori P12 7009717 YP_002301218.1 CDS HPP12_0584 NC_011498.1 613259 615289 R hypothetical protein complement(613259..615289) Helicobacter pylori P12 7009718 YP_002301219.1 CDS HPP12_0585 NC_011498.1 615295 615849 R hypothetical protein complement(615295..615849) Helicobacter pylori P12 7009719 YP_002301220.1 CDS HPP12_0586 NC_011498.1 615856 616974 R sialidase; neuraminidase complement(615856..616974) Helicobacter pylori P12 7009720 YP_002301221.1 CDS pyrC-2 NC_011498.1 616950 617969 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(616950..617969) Helicobacter pylori P12 7009721 YP_002301222.1 CDS HPP12_0588 NC_011498.1 617973 618947 R siderophore-mediated iron transport protein complement(617973..618947) Helicobacter pylori P12 7009722 YP_002301223.1 CDS HPP12_0589 NC_011498.1 618931 619812 R hypothetical protein complement(618931..619812) Helicobacter pylori P12 7009723 YP_002301224.1 CDS fliN NC_011498.1 619809 620180 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein complement(619809..620180) Helicobacter pylori P12 7009724 YP_002301225.1 CDS nth NC_011498.1 620262 620918 R endonuclease III complement(620262..620918) Helicobacter pylori P12 7009725 YP_002301226.1 CDS HPP12_0592 NC_011498.1 620915 621145 R ferrous iron transport protein A complement(620915..621145) Helicobacter pylori P12 7009726 YP_002301227.1 CDS HPP12_0593 NC_011498.1 621142 624078 R hypothetical protein complement(621142..624078) Helicobacter pylori P12 7009727 YP_002301228.1 CDS pabC NC_011498.1 623996 624985 D aminodeoxychorismate lyase 623996..624985 Helicobacter pylori P12 7009728 YP_002301229.1 CDS oorD NC_011498.1 625170 625511 D 2-oxoglutarate-acceptor oxidoreductase subunit OorD 625170..625511 Helicobacter pylori P12 7009729 YP_002301230.1 CDS oorA NC_011498.1 625511 626638 D 2-oxoglutarate-acceptor oxidoreductase subunit OorA 625511..626638 Helicobacter pylori P12 7009730 YP_002301231.1 CDS oorB NC_011498.1 626640 627461 D 2-oxoglutarate-acceptor oxidoreductase subunit OorB 626640..627461 Helicobacter pylori P12 7009731 YP_002301232.1 CDS oorC NC_011498.1 627461 628024 D 2-oxoglutarate-acceptor oxidoreductase subunit OorC 627461..628024 Helicobacter pylori P12 7009732 YP_002301233.1 CDS res-1 NC_011498.1 628179 631121 D type III R-M system restriction enzyme 628179..631121 Helicobacter pylori P12 7009733 YP_002301234.1 CDS HPP12_0601 NC_011498.1 633095 633259 D hypothetical protein 633095..633259 Helicobacter pylori P12 7009735 YP_002301235.1 CDS HPP12_0602 NC_011498.1 633269 634741 D dsbb-like protein 633269..634741 Helicobacter pylori P12 7009736 YP_002301236.1 CDS HPP12_0603 NC_011498.1 635217 635795 D Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein 635217..635795 Helicobacter pylori P12 7009737 YP_002301237.1 CDS pbp-1a NC_011498.1 635798 637777 R penicillin-binding protein 1A complement(635798..637777) Helicobacter pylori P12 7009738 YP_002301238.1 CDS bioF NC_011498.1 637778 638899 R 8-amino-7-oxononanoate synthase complement(637778..638899) Helicobacter pylori P12 7009739 YP_002301239.1 CDS HPP12_0606 NC_011498.1 638922 640223 R methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) complement(638922..640223) Helicobacter pylori P12 7009740 YP_002301240.1 CDS spab NC_011498.1 640295 641209 R multidrug resistance protein complement(640295..641209) Helicobacter pylori P12 7009741 YP_002301241.1 CDS HPP12_0608 NC_011498.1 641175 642074 R multidrug resistance protein complement(641175..642074) Helicobacter pylori P12 7009742 YP_002301242.1 CDS flaA NC_011498.1 642238 643770 D FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A 642238..643770 Helicobacter pylori P12 7009743 YP_002301243.1 CDS HPP12_0610 NC_011498.1 643912 644568 D 3-methyladenine DNA glycosylase 643912..644568 Helicobacter pylori P12 7009744 YP_002301244.1 CDS HPP12_0611 NC_011498.1 644565 645182 D hypothetical protein 644565..645182 Helicobacter pylori P12 7009745 YP_002301245.1 CDS hemE NC_011498.1 645251 646270 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 645251..646270 Helicobacter pylori P12 7009746 YP_002301246.1 CDS hefA NC_011498.1 646279 647712 D outer-membrane protein of the HefABC efflux system HefA 646279..647712 Helicobacter pylori P12 7009747 YP_002301247.1 CDS hefB NC_011498.1 647723 648427 D membrane fusion protein of the HefABC efflux system HefB 647723..648427 Helicobacter pylori P12 7009748 YP_002301248.1 CDS hefC NC_011498.1 648440 651526 D cytoplasmic pump protein of the HefABC efflux system HefC 648440..651526 Helicobacter pylori P12 7009749 YP_002301249.1 CDS HPP12_0616 NC_011498.1 651523 652092 D hypothetical protein 651523..652092 Helicobacter pylori P12 7009750 YP_002301250.1 CDS HPP12_0617 NC_011498.1 652243 660750 D vacuolating cytotoxin VacA-like protein 652243..660750 Helicobacter pylori P12 7009751 YP_002301251.1 CDS HPP12_0618 NC_011498.1 660696 661814 D vacuolating cytotoxin VacA-like protein 660696..661814 Helicobacter pylori P12 7009752 YP_002301252.1 CDS HPP12_0619 NC_011498.1 661873 662382 R ABC transporter permease complement(661873..662382) Helicobacter pylori P12 7009753 YP_002301253.1 CDS HPP12_0620 NC_011498.1 662390 662629 R ABC transporter permease complement(662390..662629) Helicobacter pylori P12 7009754 YP_002301254.1 CDS HPP12_0621 NC_011498.1 662629 663105 R ABC transporter ATP-binding protein complement(662629..663105) Helicobacter pylori P12 7009755 YP_002301255.1 CDS HPP12_0622 NC_011498.1 663089 663331 R ABC transporter ATP-binding protein complement(663089..663331) Helicobacter pylori P12 7009756 YP_002301256.1 CDS HPP12_0623 NC_011498.1 663640 663972 R hypothetical protein complement(663640..663972) Helicobacter pylori P12 7009757 YP_002301257.1 CDS ligA NC_011498.1 664126 666096 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(664126..666096) Helicobacter pylori P12 7009758 YP_002301258.1 CDS cheV-2 NC_011498.1 666174 667115 D CheA-MCP interaction modulator; chemotaxis protein 666174..667115 Helicobacter pylori P12 7009759 YP_002301259.1 CDS aspS NC_011498.1 667150 668883 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 667150..668883 Helicobacter pylori P12 7009760 YP_002301260.1 CDS adk NC_011498.1 668900 669475 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 668900..669475 Helicobacter pylori P12 7009761 YP_002301261.1 CDS HPP12_0628 NC_011498.1 669500 670717 D lipopolysaccharide biosynthesis protein 669500..670717 Helicobacter pylori P12 7009762 YP_002301262.1 CDS ppa NC_011498.1 670773 671294 D catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 670773..671294 Helicobacter pylori P12 7009763 YP_002301263.1 CDS HPP12_0630 NC_011498.1 671370 671933 D hypothetical protein 671370..671933 Helicobacter pylori P12 7009764 YP_002301264.1 CDS HPP12_0631 NC_011498.1 671950 672867 D hypothetical protein 671950..672867 Helicobacter pylori P12 7009765 YP_002301265.1 CDS HPP12_0632 NC_011498.1 672946 673329 D hypothetical protein 672946..673329 Helicobacter pylori P12 7009766 YP_002301266.1 CDS HPP12_0633 NC_011498.1 673284 673793 D hypothetical protein 673284..673793 Helicobacter pylori P12 7009767 YP_002301267.1 CDS mutS NC_011498.1 673939 676191 R MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein complement(673939..676191) Helicobacter pylori P12 7009768 YP_002301268.1 CDS HPP12_0635 NC_011498.1 676188 676565 R hypothetical protein complement(676188..676565) Helicobacter pylori P12 7009769 YP_002301269.1 CDS murC NC_011498.1 676565 677914 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(676565..677914) Helicobacter pylori P12 7009770 YP_002301270.1 CDS HPP12_0637 NC_011498.1 677907 679034 R hypothetical protein complement(677907..679034) Helicobacter pylori P12 7009771 YP_002301271.1 CDS ispG NC_011498.1 679154 680233 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 679154..680233 Helicobacter pylori P12 7009772 YP_002301272.1 CDS dapD NC_011498.1 680236 681441 D tetrahydrodipicolinate (THDP) N-succinyltransferase 680236..681441 Helicobacter pylori P12 7009773 YP_002301273.1 CDS hcpF NC_011498.1 681453 682511 D cysteine-rich protein F 681453..682511 Helicobacter pylori P12 7009774 YP_002301274.1 CDS HPP12_0641 NC_011498.1 682744 684792 D hypothetical protein 682744..684792 Helicobacter pylori P12 7009775 YP_002301275.1 CDS HPP12_0642 NC_011498.1 684837 685421 R modulator of drug activity B complement(684837..685421) Helicobacter pylori P12 7009776 YP_002301276.1 CDS hydA NC_011498.1 685582 686736 D quinone-reactive Ni/Fe hydrogenase HydA 685582..686736 Helicobacter pylori P12 7009777 YP_002301277.1 CDS hydB NC_011498.1 686746 688482 D quinone-reactive Ni/Fe hydrogenase HydB 686746..688482 Helicobacter pylori P12 7009778 YP_002301278.1 CDS hydC NC_011498.1 688495 689169 D quinone-reactive Ni/Fe hydrogenase HydC 688495..689169 Helicobacter pylori P12 7009779 YP_002301279.1 CDS hydD NC_011498.1 689166 689702 D quinone-reactive Ni/fe hydrogenase HydD 689166..689702 Helicobacter pylori P12 7009780 YP_002301280.1 CDS HPP12_0647 NC_011498.1 689704 691242 D hypothetical protein 689704..691242 Helicobacter pylori P12 7009781 YP_002301281.1 CDS HPP12_0648 NC_011498.1 691247 691660 R hypothetical protein complement(691247..691660) Helicobacter pylori P12 7009782 YP_002301282.1 CDS HPP12_0649 NC_011498.1 691797 692249 R hypothetical protein complement(691797..692249) Helicobacter pylori P12 7009783 YP_002301283.1 CDS hopH NC_011498.1 692433 693353 D outer membrane protein HopH 692433..693353 Helicobacter pylori P12 7009784 YP_002301284.1 CDS exsB NC_011498.1 693420 694106 R trans-regulatory protein ExsB complement(693420..694106) Helicobacter pylori P12 7009785 YP_002301285.1 CDS HPP12_0652 NC_011498.1 694169 695377 D poly(A) polymerase 694169..695377 Helicobacter pylori P12 7009786 YP_002301286.1 CDS HPP12_0653 NC_011498.1 695391 695894 D hypothetical protein 695391..695894 Helicobacter pylori P12 7009787 YP_002301287.1 CDS HPP12_0654 NC_011498.1 695911 696753 D 3-hydroxyacid dehydrogenase 695911..696753 Helicobacter pylori P12 7009788 YP_002301288.1 CDS HPP12_0655 NC_011498.1 696772 697425 D NAD(P)H-flavin oxidoreductase 696772..697425 Helicobacter pylori P12 7009789 YP_002301289.1 CDS gltX NC_011498.1 697590 698909 D charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase 697590..698909 Helicobacter pylori P12 7009790 YP_002301290.1 CDS HPP12_0657 NC_011498.1 698906 699199 D integral membrane protein 698906..699199 Helicobacter pylori P12 7009791 YP_002301291.1 CDS HPP12_0658 NC_011498.1 699208 700890 D soluble lytic murein transglycosylase 699208..700890 Helicobacter pylori P12 7009792 YP_002301292.1 CDS galU NC_011498.1 700887 701708 D UDP-glucose pyrophosphorylase 700887..701708 Helicobacter pylori P12 7009793 YP_002301293.1 CDS HPP12_0660 NC_011498.1 701720 702127 D hypothetical protein 701720..702127 Helicobacter pylori P12 7009794 YP_002301294.1 CDS HPP12_0661 NC_011498.1 702130 703398 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 702130..703398 Helicobacter pylori P12 7009795 YP_002301295.1 CDS aspA NC_011498.1 703456 704862 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 703456..704862 Helicobacter pylori P12 7009796 YP_002301296.1 CDS HPP12_0663 NC_011498.1 704868 705497 D hypothetical protein 704868..705497 Helicobacter pylori P12 7009797 YP_002301297.1 CDS fucT NC_011498.1 705506 706891 R alpha1,3-fucosyltransferase complement(705506..706891) Helicobacter pylori P12 7009798 YP_002301298.1 CDS serB NC_011498.1 706931 707554 R phosphoserine phosphatase complement(706931..707554) Helicobacter pylori P12 7009799 YP_002301299.1 CDS pfr NC_011498.1 707570 708073 R nonheme iron-containing ferritin complement(707570..708073) Helicobacter pylori P12 7009800 YP_002301300.1 CDS HPP12_0667 NC_011498.1 708375 709457 D hypothetical protein 708375..709457 Helicobacter pylori P12 7009801 YP_002301301.1 CDS HPP12_0668 NC_011498.1 709540 712281 D protective surface antigen D15 709540..712281 Helicobacter pylori P12 7009802 YP_002301302.1 CDS HPP12_0669 NC_011498.1 712283 713344 D hypothetical protein 712283..713344 Helicobacter pylori P12 7009803 YP_002301303.1 CDS HPP12_0670 NC_011498.1 713350 714651 D processing zinc-metalloprotease 713350..714651 Helicobacter pylori P12 7009804 YP_002301304.1 CDS gatB NC_011498.1 714651 716075 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 714651..716075 Helicobacter pylori P12 7009805 YP_002301305.1 CDS HPP12_0672 NC_011498.1 716075 717319 D hypothetical protein 716075..717319 Helicobacter pylori P12 7009806 YP_002301306.1 CDS HPP12_0673 NC_011498.1 717330 718340 D hypothetical protein 717330..718340 Helicobacter pylori P12 7009807 YP_002301307.1 CDS rnhA NC_011498.1 718207 718773 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 718207..718773 Helicobacter pylori P12 7009808 YP_002301308.1 CDS rnc NC_011498.1 718785 719504 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 718785..719504 Helicobacter pylori P12 7009809 YP_002301309.1 CDS aroC NC_011498.1 719501 720598 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 719501..720598 Helicobacter pylori P12 7009810 YP_002301310.1 CDS HPP12_0677 NC_011498.1 720635 721150 D hypothetical protein 720635..721150 Helicobacter pylori P12 7009811 YP_002301311.1 CDS hemN-1 NC_011498.1 721150 722523 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 721150..722523 Helicobacter pylori P12 7009812 YP_002301312.1 CDS glpC NC_011498.1 722520 723821 D anaerobic glycerol-3-phosphate dehydrogenase 722520..723821 Helicobacter pylori P12 7009813 YP_002301313.1 CDS HPP12_0680 NC_011498.1 723896 725884 D type II R-M system protein 723896..725884 Helicobacter pylori P12 7009814 YP_002301314.1 CDS HPP12_0681 NC_011498.1 725865 726584 D type II R-M system protein 725865..726584 Helicobacter pylori P12 7009815 YP_002301315.1 CDS HPP12_0682 NC_011498.1 726574 728628 D type II R-M system protein 726574..728628 Helicobacter pylori P12 7009816 YP_002301316.1 CDS HPP12_0683 NC_011498.1 728625 729974 D hypothetical protein 728625..729974 Helicobacter pylori P12 7009817 YP_002301317.1 CDS horF NC_011498.1 730096 730908 D outer membrane protein HorF 730096..730908 Helicobacter pylori P12 7009818 YP_002301318.1 CDS aspB NC_011498.1 731067 732239 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 731067..732239 Helicobacter pylori P12 7009819 YP_002301319.1 CDS HPP12_0686 NC_011498.1 732395 732673 D hypothetical protein 732395..732673 Helicobacter pylori P12 7009820 YP_002301320.1 CDS HPP12_0687 NC_011498.1 732674 733744 D integrase-recombinase protein 732674..733744 Helicobacter pylori P12 7009821 YP_002301321.1 CDS ogt NC_011498.1 733806 734312 R methylated-DNA-protein-cysteine methyltransferase complement(733806..734312) Helicobacter pylori P12 7009822 YP_002301322.1 CDS HPP12_0689 NC_011498.1 734316 735083 R integral membrane protein complement(734316..735083) Helicobacter pylori P12 7009823 YP_002301323.1 CDS wbpB NC_011498.1 735197 736144 R lipopolysaccharide biosynthesis protein WbpB complement(735197..736144) Helicobacter pylori P12 7009824 YP_002301324.1 CDS nrdA NC_011498.1 736206 738572 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(736206..738572) Helicobacter pylori P12 7009825 YP_002301325.1 CDS HPP12_0692 NC_011498.1 738737 739219 R hypothetical protein complement(738737..739219) Helicobacter pylori P12 7009826 YP_002301326.1 CDS HPP12_0693 NC_011498.1 739243 739578 R hypothetical protein complement(739243..739578) Helicobacter pylori P12 7009827 YP_002301327.1 CDS HPP12_0694 NC_011498.1 739901 740404 R hypothetical protein complement(739901..740404) Helicobacter pylori P12 7009828 YP_002301328.1 CDS HPP12_0695 NC_011498.1 740444 740773 R hypothetical protein complement(740444..740773) Helicobacter pylori P12 7009829 YP_002301329.1 CDS glmU NC_011498.1 740976 742277 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(740976..742277) Helicobacter pylori P12 7009830 YP_002301330.1 CDS fliP NC_011498.1 742323 743105 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 742323..743105 Helicobacter pylori P12 7009831 YP_002301331.1 CDS fecA-1 NC_011498.1 743142 745445 R iron(III) dicitrate transport protein complement(743142..745445) Helicobacter pylori P12 7009832 YP_002301332.1 CDS feoB NC_011498.1 745698 747626 R iron(II) transport protein complement(745698..747626) Helicobacter pylori P12 7009833 YP_002301333.1 CDS HPP12_0700 NC_011498.1 747764 748576 D hypothetical protein 747764..748576 Helicobacter pylori P12 7009834 YP_002301334.1 CDS HPP12_0701 NC_011498.1 748858 750033 D acetyl coenzyme A acetyltransferase 748858..750033 Helicobacter pylori P12 7009835 YP_002301335.1 CDS scoA NC_011498.1 750044 750742 D succinyl-coa-transferase subunit A 750044..750742 Helicobacter pylori P12 7009836 YP_002301336.1 CDS scoB NC_011498.1 750739 751362 D succinyl-coa-transferase subunit B 750739..751362 Helicobacter pylori P12 7009837 YP_002301337.1 CDS atoE NC_011498.1 751382 752746 D short-chain fatty acids transporter 751382..752746 Helicobacter pylori P12 7009838 YP_002301338.1 CDS HPP12_0705 NC_011498.1 752870 753871 D outer membrane protein 752870..753871 Helicobacter pylori P12 7009839 YP_002301339.1 CDS HPP12_0707 NC_011498.1 756270 758567 D N-methylhydantoinase B 756270..758567 Helicobacter pylori P12 7009841 YP_002301340.1 CDS HPP12_0708 NC_011498.1 758584 759084 D acetone carboxylase gamma subunit 758584..759084 Helicobacter pylori P12 7009842 YP_002301341.1 CDS HPP12_0709 NC_011498.1 759419 760447 D hypothetical protein 759419..760447 Helicobacter pylori P12 7009843 YP_002301342.1 CDS dgkA NC_011498.1 760440 760826 D diacylglycerol kinase 760440..760826 Helicobacter pylori P12 7009844 YP_002301343.1 CDS gyrA NC_011498.1 760846 763326 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 760846..763326 Helicobacter pylori P12 7009845 YP_002301344.1 CDS HPP12_0712 NC_011498.1 763326 763799 D hypothetical protein 763326..763799 Helicobacter pylori P12 7009846 YP_002301345.1 CDS HPP12_0713 NC_011498.1 763796 764941 D transcriptional activator of flagella proteins 763796..764941 Helicobacter pylori P12 7009847 YP_002301346.1 CDS HPP12_0714 NC_011498.1 765015 765323 D hypothetical protein 765015..765323 Helicobacter pylori P12 7009848 YP_002301347.1 CDS HPP12_0715 NC_011498.1 765290 765598 D hypothetical protein 765290..765598 Helicobacter pylori P12 7009849 YP_002301348.1 CDS uvrA NC_011498.1 765847 768672 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(765847..768672) Helicobacter pylori P12 7009850 YP_002301349.1 CDS hopE NC_011498.1 768837 769658 D outer membrane protein HopE 768837..769658 Helicobacter pylori P12 7009851 YP_002301350.1 CDS mraW NC_011498.1 769839 770765 D S-adenosyl-methyltransferase MraW 769839..770765 Helicobacter pylori P12 7009852 YP_002301351.1 CDS HPP12_0719 NC_011498.1 770786 771130 D hypothetical protein 770786..771130 Helicobacter pylori P12 7009853 YP_002301352.1 CDS HPP12_0720 NC_011498.1 771329 772231 D hypothetical protein 771329..772231 Helicobacter pylori P12 7009854 YP_002301353.1 CDS homB NC_011498.1 772456 774465 D outer membrane protein HomB 772456..774465 Helicobacter pylori P12 7009855 YP_002301354.1 CDS HPP12_0722 NC_011498.1 774653 775873 D hypothetical protein 774653..775873 Helicobacter pylori P12 7009856 YP_002301355.1 CDS rpoN NC_011498.1 775986 777230 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 complement(775986..777230) Helicobacter pylori P12 7009857 YP_002301356.1 CDS HPP12_0724 NC_011498.1 777233 777955 R ABC transporter ATP-binding protein complement(777233..777955) Helicobacter pylori P12 7009858 YP_002301357.1 CDS HPP12_0725 NC_011498.1 777968 778369 R hypothetical protein complement(777968..778369) Helicobacter pylori P12 7009859 YP_002301358.1 CDS dnaX NC_011498.1 778366 780096 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(778366..780096) Helicobacter pylori P12 7009860 YP_002301359.1 CDS HPP12_0727 NC_011498.1 780164 780796 R integral membrane protein complement(780164..780796) Helicobacter pylori P12 7009861 YP_002301360.1 CDS HPP12_0728 NC_011498.1 781060 781482 D hypothetical protein 781060..781482 Helicobacter pylori P12 7009862 YP_002301361.1 CDS HPP12_0729 NC_011498.1 781511 781972 D hypothetical protein 781511..781972 Helicobacter pylori P12 7009863 YP_002301362.1 CDS sabB NC_011498.1 782345 784216 D outer membrane protein SabB/HopO 782345..784216 Helicobacter pylori P12 7009864 YP_002301363.1 CDS ansB NC_011498.1 784356 785354 R L-asparaginase type II complement(784356..785354) Helicobacter pylori P12 7009865 YP_002301364.1 CDS dcuA NC_011498.1 785483 786814 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 785483..786814 Helicobacter pylori P12 7009866 YP_002301365.1 CDS sabB_2 NC_011498.1 786888 788759 R outer membrane protein SabB/HopO complement(786888..788759) Helicobacter pylori P12 7009867 YP_002301366.1 CDS HPP12_0734 NC_011498.1 789027 789944 R outer membrane protein complement(789027..789944) Helicobacter pylori P12 7009868 YP_002301367.1 CDS HPP12_0735 NC_011498.1 789914 790900 R transcriptional regulator complement(789914..790900) Helicobacter pylori P12 7009869 YP_002301368.1 CDS HPP12_0736 NC_011498.1 790992 792008 R tRNA(Ile)-lysidine synthetase complement(790992..792008) Helicobacter pylori P12 7009870 YP_002301369.1 CDS HPP12_0737 NC_011498.1 792044 792823 R ATP/GTP binding protein complement(792044..792823) Helicobacter pylori P12 7009871 YP_002301370.1 CDS HPP12_0738 NC_011498.1 792787 793110 R ATP/GTP binding protein complement(792787..793110) Helicobacter pylori P12 7009872 YP_002301371.1 CDS HPP12_0739 NC_011498.1 793119 793424 R hypothetical protein complement(793119..793424) Helicobacter pylori P12 7009873 YP_002301372.1 CDS HPP12_0740 NC_011498.1 793538 795229 R ATP/GTP binding protein complement(793538..795229) Helicobacter pylori P12 7009874 YP_002301373.1 CDS HPP12_0741 NC_011498.1 795226 796323 R hypothetical protein complement(795226..796323) Helicobacter pylori P12 7009875 YP_002301374.1 CDS HPP12_0742 NC_011498.1 796341 796967 R hypothetical protein complement(796341..796967) Helicobacter pylori P12 7009876 YP_002301375.1 CDS HPP12_0743 NC_011498.1 797187 798506 R 2-methylthioadenine synthetase complement(797187..798506) Helicobacter pylori P12 7009877 YP_002301376.1 CDS gpt NC_011498.1 798508 798969 R xanthine-guanine phosphoribosyl transferase complement(798508..798969) Helicobacter pylori P12 7009878 YP_002301377.1 CDS HPP12_0745 NC_011498.1 798978 800087 R phosphoserine aminotransferase complement(798978..800087) Helicobacter pylori P12 7009879 YP_002301378.1 CDS pgpA NC_011498.1 800236 800712 D phosphatidylglycerophosphatase A 800236..800712 Helicobacter pylori P12 7009880 YP_002301379.1 CDS ddl NC_011498.1 800789 801832 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 800789..801832 Helicobacter pylori P12 7009881 YP_002301380.1 CDS HPP12_0748 NC_011498.1 801832 802557 D 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase 801832..802557 Helicobacter pylori P12 7009882 YP_002301381.1 CDS murF NC_011498.1 802544 804025 D UDP-murnac-pentapeptide presynthetase 802544..804025 Helicobacter pylori P12 7009883 YP_002301382.1 CDS HPP12_0750 NC_011498.1 804035 804520 D histidine triad (HIT) family protein 804035..804520 Helicobacter pylori P12 7009884 YP_002301383.1 CDS prsA NC_011498.1 804585 805541 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 804585..805541 Helicobacter pylori P12 7009885 YP_002301384.1 CDS rodA NC_011498.1 805602 806723 R rod shape-determining protein complement(805602..806723) Helicobacter pylori P12 7009887 YP_002301385.1 CDS HPP12_0753 NC_011498.1 806770 807309 R hypothetical protein complement(806770..807309) Helicobacter pylori P12 7009888 YP_002301386.1 CDS HPP12_0754 NC_011498.1 807536 807988 R hypothetical protein complement(807536..807988) Helicobacter pylori P12 7009889 YP_002301387.1 CDS HPP12_0755 NC_011498.1 808124 809107 D pseudouridine synthase D 808124..809107 Helicobacter pylori P12 7009890 YP_002301388.1 CDS HPP12_0756 NC_011498.1 809058 810317 D fibronectin domain-containing lipoprotein 809058..810317 Helicobacter pylori P12 7009891 YP_002301389.1 CDS trmB NC_011498.1 810328 811509 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 810328..811509 Helicobacter pylori P12 7009892 YP_002301390.1 CDS ftsE NC_011498.1 811506 812177 D ABC transporter ATP-binding protein; cell division protein FtsE 811506..812177 Helicobacter pylori P12 7009893 YP_002301391.1 CDS ftsX NC_011498.1 812164 812970 D cell division protein FtsX 812164..812970 Helicobacter pylori P12 7009894 YP_002301392.1 CDS HPP12_0760 NC_011498.1 812963 814165 D hypothetical protein 812963..814165 Helicobacter pylori P12 7009895 YP_002301393.1 CDS flaG-2 NC_011498.1 814258 814617 D possibly involved in flagella export; flagellar protein FlaG 814258..814617 Helicobacter pylori P12 7009896 YP_002301394.1 CDS fliD NC_011498.1 814657 816714 D involved in flagellin assembly; flagellar capping protein 814657..816714 Helicobacter pylori P12 7009897 YP_002301395.1 CDS fliS NC_011498.1 816756 817136 D flagellin specific chaperone; flagellar protein FliS 816756..817136 Helicobacter pylori P12 7009898 YP_002301396.1 CDS HPP12_0764 NC_011498.1 817123 817362 D hypothetical protein 817123..817362 Helicobacter pylori P12 7009899 YP_002301397.1 CDS moeB NC_011498.1 817416 818075 D molybdopterin biosynthesis protein 817416..818075 Helicobacter pylori P12 7009900 YP_002301398.1 CDS HPP12_0766 NC_011498.1 818101 818244 D hypothetical protein 818101..818244 Helicobacter pylori P12 7009901 YP_002301399.1 CDS HPP12_0767 NC_011498.1 818248 819126 D carbon-nitrogen hydrolase 818248..819126 Helicobacter pylori P12 7009902 YP_002301400.1 CDS HPP12_0768 NC_011498.1 819259 820572 D permease/na-h antiporter 819259..820572 Helicobacter pylori P12 7009903 YP_002301401.1 CDS HPP12_0769 NC_011498.1 820635 821888 D DNA-damage induced multidrug efflux protein 820635..821888 Helicobacter pylori P12 7009904 YP_002301402.1 CDS HPP12_0770 NC_011498.1 821889 823478 R protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase complement(821889..823478) Helicobacter pylori P12 7009905 YP_002301403.1 CDS HPP12_0771 NC_011498.1 823378 823980 R hypothetical protein complement(823378..823980) Helicobacter pylori P12 7009906 YP_002301404.1 CDS HPP12_0772 NC_011498.1 824144 824701 D hypothetical protein 824144..824701 Helicobacter pylori P12 7009907 YP_002301405.1 CDS ftsY NC_011498.1 824707 825588 D signal recognition particle receptor; cell division protein FtsY 824707..825588 Helicobacter pylori P12 7009908 YP_002301406.1 CDS HPP12_0774 NC_011498.1 825655 826269 R hypothetical protein complement(825655..826269) Helicobacter pylori P12 7009909 YP_002301407.1 CDS HPP12_0775 NC_011498.1 826049 826546 R hypothetical protein complement(826049..826546) Helicobacter pylori P12 7009910 YP_002301408.1 CDS HPP12_0776 NC_011498.1 826543 826695 R hypothetical protein complement(826543..826695) Helicobacter pylori P12 7009911 YP_002301409.1 CDS moaA NC_011498.1 826795 827760 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(826795..827760) Helicobacter pylori P12 7009912 YP_002301410.1 CDS HPP12_0778 NC_011498.1 827847 828452 D MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 827847..828452 Helicobacter pylori P12 7009913 YP_002301411.1 CDS flhB NC_011498.1 828445 829521 D membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 828445..829521 Helicobacter pylori P12 7009914 YP_002301412.1 CDS HPP12_0780 NC_011498.1 829616 830353 R hypothetical protein complement(829616..830353) Helicobacter pylori P12 7009915 YP_002301413.1 CDS amiA NC_011498.1 830372 831703 R N-acetylmuramoyl-L-alanine amidase complement(830372..831703) Helicobacter pylori P12 7009916 YP_002301414.1 CDS HPP12_0782 NC_011498.1 831710 832801 R flavin-containing oxidoreductase complement(831710..832801) Helicobacter pylori P12 7009917 YP_002301415.1 CDS tyrS NC_011498.1 832818 834026 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(832818..834026) Helicobacter pylori P12 7009918 YP_002301416.1 CDS spoT NC_011498.1 834050 836377 R penta-phosphate guanosine-3'-pyrophosphohydrolase complement(834050..836377) Helicobacter pylori P12 7009919 YP_002301417.1 CDS HPP12_0785 NC_011498.1 836364 836588 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(836364..836588) Helicobacter pylori P12 7009920 YP_002301418.1 CDS pyrH NC_011498.1 836630 837352 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(836630..837352) Helicobacter pylori P12 7009921 YP_002301419.1 CDS HPP12_0787 NC_011498.1 837455 838138 R hypothetical protein complement(837455..838138) Helicobacter pylori P12 7009922 YP_002301420.1 CDS acnB NC_011498.1 838269 840827 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 838269..840827 Helicobacter pylori P12 7009923 YP_002301421.1 CDS HPP12_0789 NC_011498.1 840908 841174 D hypothetical protein 840908..841174 Helicobacter pylori P12 7009924 YP_002301422.1 CDS HPP12_0790 NC_011498.1 841441 842730 D hypothetical protein 841441..842730 Helicobacter pylori P12 7009925 YP_002301423.1 CDS hofE NC_011498.1 842824 844191 D outermembrane protein HofE 842824..844191 Helicobacter pylori P12 7009926 YP_002301424.1 CDS HPP12_0792 NC_011498.1 844198 844725 R hypothetical protein complement(844198..844725) Helicobacter pylori P12 7009927 YP_002301425.1 CDS lolA NC_011498.1 845208 845762 R participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein complement(845208..845762) Helicobacter pylori P12 7009928 YP_002301426.1 CDS secA NC_011498.1 845910 848507 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 845910..848507 Helicobacter pylori P12 7009929 YP_002301427.1 CDS lolE NC_011498.1 848497 849729 D lipoprotein release system transmembrane protein LolE 848497..849729 Helicobacter pylori P12 7009930 YP_002301428.1 CDS hofF NC_011498.1 850011 851510 D outer membrane protein HofF 850011..851510 Helicobacter pylori P12 7009931 YP_002301429.1 CDS hsdS-2 NC_011498.1 851843 853141 R type I R-M system S protein complement(851843..853141) Helicobacter pylori P12 7009932 YP_002301430.1 CDS HPP12_0798 NC_011498.1 853182 855242 R p-type transporting ATPase involved in transition metal resistance; cadmium-transporting ATPase complement(853182..855242) Helicobacter pylori P12 7009933 YP_002301431.1 CDS HPP12_0799 NC_011498.1 855267 856787 R sigma-54 interacting protein complement(855267..856787) Helicobacter pylori P12 7009934 YP_002301432.1 CDS def NC_011498.1 856793 857317 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(856793..857317) Helicobacter pylori P12 7009935 YP_002301433.1 CDS clpP NC_011498.1 857322 857909 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(857322..857909) Helicobacter pylori P12 7009936 YP_002301434.1 CDS tig NC_011498.1 857930 859285 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(857930..859285) Helicobacter pylori P12 7009937 YP_002301435.1 CDS horG NC_011498.1 859397 860233 R outer membrane protein HorG complement(859397..860233) Helicobacter pylori P12 7009938 YP_002301436.1 CDS hpaA NC_011498.1 860262 861044 R flagellar sheath adhesin HpaA complement(860262..861044) Helicobacter pylori P12 7009939 YP_002301437.1 CDS moaC NC_011498.1 861163 861639 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(861163..861639) Helicobacter pylori P12 7009940 YP_002301438.1 CDS mogA NC_011498.1 861648 862178 R forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA complement(861648..862178) Helicobacter pylori P12 7009941 YP_002301439.1 CDS moaE NC_011498.1 862191 862628 R molybdopterin converting factor subunit 2 complement(862191..862628) Helicobacter pylori P12 7009942 YP_002301440.1 CDS ribA NC_011498.1 862931 863509 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(862931..863509) Helicobacter pylori P12 7009943 YP_002301441.1 CDS HPP12_0809 NC_011498.1 863599 864438 R hypothetical protein complement(863599..864438) Helicobacter pylori P12 7009944 YP_002301442.1 CDS HPP12_0810 NC_011498.1 864525 865559 R bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein complement(864525..865559) Helicobacter pylori P12 7009945 YP_002301443.1 CDS HPP12_0811 NC_011498.1 865642 866478 R lipopolysaccharide biosynthesis protein complement(865642..866478) Helicobacter pylori P12 7009946 YP_002301444.1 CDS HPP12_0812 NC_011498.1 866560 867180 D metalloprotease 866560..867180 Helicobacter pylori P12 7009947 YP_002301445.1 CDS HPP12_0813 NC_011498.1 867192 869570 R iron(III) dicitrate transport protein complement(867192..869570) Helicobacter pylori P12 7009948 YP_002301446.1 CDS acpS NC_011498.1 869773 870129 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(869773..870129) Helicobacter pylori P12 7009949 YP_002301447.1 CDS fliL NC_011498.1 870136 870687 R interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL complement(870136..870687) Helicobacter pylori P12 7009950 YP_002301448.1 CDS HPP12_0816 NC_011498.1 870696 871298 R N-6 adenine methyltransferase complement(870696..871298) Helicobacter pylori P12 7009951 YP_002301449.1 CDS HPP12_0817 NC_011498.1 871277 871603 R hypothetical protein complement(871277..871603) Helicobacter pylori P12 7009952 YP_002301450.1 CDS HPP12_0818 NC_011498.1 871958 872962 R hypothetical protein complement(871958..872962) Helicobacter pylori P12 7009953 YP_002301451.1 CDS HPP12_0819 NC_011498.1 873096 873713 D hypothetical protein 873096..873713 Helicobacter pylori P12 7009954 YP_002301452.1 CDS HPP12_0820 NC_011498.1 873714 874481 D thiamine biosynthesis protein 873714..874481 Helicobacter pylori P12 7009955 YP_002301453.1 CDS motA NC_011498.1 874497 875270 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 874497..875270 Helicobacter pylori P12 7009956 YP_002301454.1 CDS motB NC_011498.1 875273 876046 D with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 875273..876046 Helicobacter pylori P12 7009957 YP_002301455.1 CDS HPP12_0823 NC_011498.1 876043 876489 D hypothetical protein 876043..876489 Helicobacter pylori P12 7009958 YP_002301456.1 CDS HPP12_0824 NC_011498.1 876548 876694 D osmoprotection protein 876548..876694 Helicobacter pylori P12 7009959 YP_002301457.1 CDS proWX NC_011498.1 876936 878486 D osmoprotection protein 876936..878486 Helicobacter pylori P12 7009960 YP_002301458.1 CDS proV NC_011498.1 878490 879131 D ATP-binding protein; osmoprotection ABC transporter 878490..879131 Helicobacter pylori P12 7009961 YP_002301459.1 CDS HPP12_0827 NC_011498.1 879314 879775 D hypothetical protein 879314..879775 Helicobacter pylori P12 7009962 YP_002301460.1 CDS uvrC NC_011498.1 879776 881560 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 879776..881560 Helicobacter pylori P12 7009963 YP_002301461.1 CDS hom NC_011498.1 881571 882836 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 881571..882836 Helicobacter pylori P12 7009964 YP_002301462.1 CDS HPP12_0830 NC_011498.1 882837 883181 D hypothetical protein 882837..883181 Helicobacter pylori P12 7009965 YP_002301463.1 CDS trxA NC_011498.1 883270 883590 D thioredoxin 883270..883590 Helicobacter pylori P12 7009966 YP_002301464.1 CDS trxB-1 NC_011498.1 883595 884530 D thioredoxin reductase 883595..884530 Helicobacter pylori P12 7009967 YP_002301465.1 CDS HPP12_0833 NC_011498.1 884741 885562 D beta-1,4-galactosyltransferase 884741..885562 Helicobacter pylori P12 7009968 YP_002301466.1 CDS HPP12_0834 NC_011498.1 885783 886031 R RNA-binding protein complement(885783..886031) Helicobacter pylori P12 7009969 YP_002301467.1 CDS atpB NC_011498.1 886354 887034 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(886354..887034) Helicobacter pylori P12 7009970 YP_002301468.1 CDS guaB NC_011498.1 887156 888601 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(887156..888601) Helicobacter pylori P12 7009971 YP_002301469.1 CDS gatA NC_011498.1 888611 889972 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(888611..889972) Helicobacter pylori P12 7009972 YP_002301470.1 CDS coaE NC_011498.1 890031 890621 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(890031..890621) Helicobacter pylori P12 7009973 YP_002301471.1 CDS speE NC_011498.1 890623 891411 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(890623..891411) Helicobacter pylori P12 7009974 YP_002301472.1 CDS HPP12_0840 NC_011498.1 891503 892381 R hypothetical protein complement(891503..892381) Helicobacter pylori P12 7009975 YP_002301473.1 CDS engA NC_011498.1 892458 893846 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 892458..893846 Helicobacter pylori P12 7009976 YP_002301474.1 CDS HPP12_0842 NC_011498.1 893987 894271 D histone-like DNA-binding protein hu 893987..894271 Helicobacter pylori P12 7009977 YP_002301475.1 CDS HPP12_0843 NC_011498.1 894873 895478 D hypothetical protein 894873..895478 Helicobacter pylori P12 7009979 YP_002301476.1 CDS HPP12_0844 NC_011498.1 895508 896125 D hypothetical protein 895508..896125 Helicobacter pylori P12 7009980 YP_002301477.1 CDS ompP1 NC_011498.1 896122 897885 D outer membrane transport protein P1 896122..897885 Helicobacter pylori P12 7009981 YP_002301478.1 CDS HPP12_0846 NC_011498.1 897889 898890 D bifunctional UDP-glcnac C6 dehydratase / C5 epimerase 897889..898890 Helicobacter pylori P12 7009982 YP_002301479.1 CDS dfp NC_011498.1 898887 900164 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 898887..900164 Helicobacter pylori P12 7009983 YP_002301480.1 CDS HPP12_0848 NC_011498.1 900164 900901 D hypothetical protein 900164..900901 Helicobacter pylori P12 7009984 YP_002301481.1 CDS hsdS-3 NC_011498.1 900914 901447 R type I R-M system S protein complement(900914..901447) Helicobacter pylori P12 7009985 YP_002301482.1 CDS hsdM-2 NC_011498.1 901440 903023 R type I R-M system M protein complement(901440..903023) Helicobacter pylori P12 7009986 YP_002301483.1 CDS HPP12_0851 NC_011498.1 903199 903885 D integral membrane protein 903199..903885 Helicobacter pylori P12 7009987 YP_002301484.1 CDS HPP12_0852 NC_011498.1 903909 904277 R hypothetical protein complement(903909..904277) Helicobacter pylori P12 7009988 YP_002301485.1 CDS HPP12_0853 NC_011498.1 904214 904852 R hypothetical protein complement(904214..904852) Helicobacter pylori P12 7009989 YP_002301486.1 CDS HPP12_0854 NC_011498.1 904849 906450 R ABC transporter ATP-binding protein complement(904849..906450) Helicobacter pylori P12 7009990 YP_002301487.1 CDS HPP12_0855 NC_011498.1 906619 907626 D guanosine 5'-monophosphate oxidoreductase 906619..907626 Helicobacter pylori P12 7009991 YP_002301488.1 CDS HPP12_0856 NC_011498.1 907623 907772 R hypothetical protein complement(907623..907772) Helicobacter pylori P12 7009992 YP_002301489.1 CDS gmhA NC_011498.1 907744 908322 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(907744..908322) Helicobacter pylori P12 7009993 YP_002301490.1 CDS waaE NC_011498.1 908315 909700 R ADP-heptose synthase complement(908315..909700) Helicobacter pylori P12 7009994 YP_002301491.1 CDS HPP12_0859 NC_011498.1 909697 910689 R ADP-L-glycero-D-mannoheptose-6-epimerase complement(909697..910689) Helicobacter pylori P12 7009995 YP_002301492.1 CDS HPP12_0860 NC_011498.1 910699 911220 R histidinol phosphatase complement(910699..911220) Helicobacter pylori P12 7009996 YP_002301493.1 CDS HPP12_0861 NC_011498.1 911210 911950 R hypothetical protein complement(911210..911950) Helicobacter pylori P12 7009997 YP_002301494.1 CDS HPP12_0862 NC_011498.1 911941 912612 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(911941..912612) Helicobacter pylori P12 7009998 YP_002301495.1 CDS HPP12_0863 NC_011498.1 912617 914242 R hypothetical protein complement(912617..914242) Helicobacter pylori P12 7009999 YP_002301496.1 CDS HPP12_0864 NC_011498.1 914247 914903 R hypothetical protein complement(914247..914903) Helicobacter pylori P12 7010000 YP_002301497.1 CDS dut NC_011498.1 914900 915337 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(914900..915337) Helicobacter pylori P12 7010001 YP_002301498.1 CDS greA NC_011498.1 915327 915821 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(915327..915821) Helicobacter pylori P12 7010002 YP_002301499.1 CDS lpxB NC_011498.1 915862 916944 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase complement(915862..916944) Helicobacter pylori P12 7010003 YP_002301500.1 CDS HPP12_0868 NC_011498.1 916944 917405 R hypothetical protein complement(916944..917405) Helicobacter pylori P12 7010004 YP_002301501.1 CDS hypA NC_011498.1 917412 917765 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein complement(917412..917765) Helicobacter pylori P12 7010005 YP_002301502.1 CDS flgE NC_011498.1 917824 919980 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(917824..919980) Helicobacter pylori P12 7010006 YP_002301503.1 CDS cdh NC_011498.1 920187 920921 R CDP-diacylglycerol pyrophosphatase complement(920187..920921) Helicobacter pylori P12 7010007 YP_002301504.1 CDS phnA NC_011498.1 921273 921602 D alkylphosphonate uptake protein 921273..921602 Helicobacter pylori P12 7010008 YP_002301505.1 CDS HPP12_0873 NC_011498.1 921659 921874 R hypothetical protein complement(921659..921874) Helicobacter pylori P12 7010009 YP_002301506.1 CDS HPP12_0874 NC_011498.1 921959 922834 R hypothetical protein complement(921959..922834) Helicobacter pylori P12 7010010 YP_002301507.1 CDS katA NC_011498.1 922979 924496 R catalase complement(922979..924496) Helicobacter pylori P12 7010011 YP_002301508.1 CDS frpB-1 NC_011498.1 924819 927194 D iron-regulated outer membrane protein 924819..927194 Helicobacter pylori P12 7010012 YP_002301509.1 CDS ruvC NC_011498.1 927195 927668 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(927195..927668) Helicobacter pylori P12 7010013 YP_002301510.1 CDS HPP12_0878 NC_011498.1 927800 928525 D hypothetical protein 927800..928525 Helicobacter pylori P12 7010014 YP_002301511.1 CDS HPP12_0879 NC_011498.1 929714 930559 R hypothetical protein complement(929714..930559) Helicobacter pylori P12 7010015 YP_002301512.1 CDS ruvA NC_011498.1 930589 931140 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(930589..931140) Helicobacter pylori P12 7010016 YP_002301513.1 CDS HPP12_0881 NC_011498.1 931166 933010 R hypothetical protein complement(931166..933010) Helicobacter pylori P12 7010017 YP_002301514.1 CDS mviN NC_011498.1 933103 934563 D virulence factor MviN protein 933103..934563 Helicobacter pylori P12 7010018 YP_002301515.1 CDS cysS NC_011498.1 934564 935961 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 934564..935961 Helicobacter pylori P12 7010019 YP_002301516.1 CDS vacA NC_011498.1 936186 940076 D vacuolating cytotoxin VacA 936186..940076 Helicobacter pylori P12 7010020 YP_002301517.1 CDS fecE NC_011498.1 940142 940909 R ATP-binding protein; iron(III) dicitrate ABC transporter FecE complement(940142..940909) Helicobacter pylori P12 7010021 YP_002301518.1 CDS fecD NC_011498.1 940909 941889 R permease protein; iron(III) dicitrate ABC transporter FecD complement(940909..941889) Helicobacter pylori P12 7010022 YP_002301519.1 CDS HPP12_0887 NC_011498.1 941882 942736 R short-chain oxidoreductase complement(941882..942736) Helicobacter pylori P12 7010023 YP_002301520.1 CDS HPP12_0888 NC_011498.1 942876 943400 D acyl coenzyme A thioesterase 942876..943400 Helicobacter pylori P12 7010024 YP_002301521.1 CDS HPP12_0889 NC_011498.1 943567 943830 R hypothetical protein complement(943567..943830) Helicobacter pylori P12 7010025 YP_002301522.1 CDS HPP12_0890 NC_011498.1 943763 944137 R hypothetical protein complement(943763..944137) Helicobacter pylori P12 7010026 YP_002301523.1 CDS babA NC_011498.1 944495 946729 R outer membrane protein BabA complement(944495..946729) Helicobacter pylori P12 7010027 YP_002301524.1 CDS HPP12_0892 NC_011498.1 947152 947823 D hypothetical protein 947152..947823 Helicobacter pylori P12 7010029 YP_002301525.1 CDS HPP12_0893 NC_011498.1 947676 947948 R hypothetical protein complement(947676..947948) Helicobacter pylori P12 7010031 YP_002301526.1 CDS hypD NC_011498.1 947915 949027 R hydrogenase expression/formation protein HypD complement(947915..949027) Helicobacter pylori P12 7010032 YP_002301527.1 CDS hypC NC_011498.1 949045 949281 R hydrogenase expression/formation protein HypC complement(949045..949281) Helicobacter pylori P12 7010033 YP_002301528.1 CDS hypB NC_011498.1 949281 950009 R hydrogenase expression/formation protein HypB complement(949281..950009) Helicobacter pylori P12 7010034 YP_002301529.1 CDS HPP12_0897 NC_011498.1 950124 950252 R hypothetical protein complement(950124..950252) Helicobacter pylori P12 7010035 YP_002301530.1 CDS HPP12_0898 NC_011498.1 950263 950562 R hypothetical protein complement(950263..950562) Helicobacter pylori P12 7010036 YP_002301531.1 CDS ackA-3 NC_011498.1 950660 951016 R acetate kinase complement(950660..951016) Helicobacter pylori P12 7010037 YP_002301532.1 CDS ackA-2 NC_011498.1 950979 951587 R acetate kinase complement(950979..951587) Helicobacter pylori P12 7010038 YP_002301533.1 CDS ackA-1 NC_011498.1 951565 951861 R acetate kinase complement(951565..951861) Helicobacter pylori P12 7010039 YP_002301534.1 CDS pta-2 NC_011498.1 951879 952418 R phosphotransacetylase complement(951879..952418) Helicobacter pylori P12 7010040 YP_002301535.1 CDS pta-1 NC_011498.1 952453 953424 R phosphotransacetylase complement(952453..953424) Helicobacter pylori P12 7010041 YP_002301536.1 CDS HPP12_0904 NC_011498.1 953673 955193 D hypothetical protein 953673..955193 Helicobacter pylori P12 7010042 YP_002301537.1 CDS flgD NC_011498.1 955244 956263 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 955244..956263 Helicobacter pylori P12 7010043 YP_002301538.1 CDS flgE NC_011498.1 956260 958077 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 956260..958077 Helicobacter pylori P12 7010044 YP_002301539.1 CDS HPP12_0907 NC_011498.1 958129 958707 D type II R-M system restriction endonuclease 958129..958707 Helicobacter pylori P12 7010045 YP_002301540.1 CDS HPP12_0908 NC_011498.1 958717 959868 D adenine specific DNA methyltransferase 958717..959868 Helicobacter pylori P12 7010046 YP_002301541.1 CDS rep NC_011498.1 959872 961899 D single-stranded DNA-dependent ATPase; Rep helicase 959872..961899 Helicobacter pylori P12 7010047 YP_002301542.1 CDS alpA NC_011498.1 962720 964276 D outer membrane protein HopC/AlpA 962720..964276 Helicobacter pylori P12 7010048 YP_002301543.1 CDS alpB NC_011498.1 964298 965887 D outer membrane protein HopB/AlpB 964298..965887 Helicobacter pylori P12 7010049 YP_002301544.1 CDS hofG NC_011498.1 966562 968106 R outer membrane protein HofG complement(966562..968106) Helicobacter pylori P12 7010050 YP_002301545.1 CDS frpB-3 NC_011498.1 968351 968794 R iron-regulated outer membrane protein complement(968351..968794) Helicobacter pylori P12 7010051 YP_002301546.1 CDS frpB-2 NC_011498.1 968819 970792 R iron-regulated outer membrane protein complement(968819..970792) Helicobacter pylori P12 7010052 YP_002301547.1 CDS HPP12_0915 NC_011498.1 971052 971483 R hypothetical protein complement(971052..971483) Helicobacter pylori P12 7010053 YP_002301548.1 CDS carB NC_011498.1 971488 974745 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(971488..974745) Helicobacter pylori P12 7010054 YP_002301549.1 CDS HPP12_0917 NC_011498.1 974845 975537 R integral membrane protein complement(974845..975537) Helicobacter pylori P12 7010055 YP_002301550.1 CDS HPP12_0918 NC_011498.1 975681 976679 D glyceraldehyde-3-phosphate dehydrogenase 975681..976679 Helicobacter pylori P12 7010056 YP_002301551.1 CDS HPP12_0919 NC_011498.1 976759 983877 D vacuolating cytotoxin VacA-like protein 976759..983877 Helicobacter pylori P12 7010057 YP_002301552.1 CDS hopK NC_011498.1 983929 985038 D outer membrane protein HopK 983929..985038 Helicobacter pylori P12 7010058 YP_002301553.1 CDS HPP12_0921 NC_011498.1 985100 985306 R 4-oxalocrotonate tautomerase complement(985100..985306) Helicobacter pylori P12 7010059 YP_002301554.1 CDS recR NC_011498.1 985468 986049 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 985468..986049 Helicobacter pylori P12 7010060 YP_002301555.1 CDS truD NC_011498.1 986046 987191 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 986046..987191 Helicobacter pylori P12 7010061 YP_002301556.1 CDS htpX NC_011498.1 987178 988110 D putative metalloprotease; heat shock protein HtpX 987178..988110 Helicobacter pylori P12 7010062 YP_002301557.1 CDS folE NC_011498.1 988111 988653 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 988111..988653 Helicobacter pylori P12 7010063 YP_002301558.1 CDS ispA NC_011498.1 988669 989580 D trans-isoprenyl diphosphate synthase 988669..989580 Helicobacter pylori P12 7010064 YP_002301559.1 CDS surE NC_011498.1 989577 990380 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 989577..990380 Helicobacter pylori P12 7010065 YP_002301560.1 CDS HPP12_0928 NC_011498.1 990377 991036 D hypothetical protein 990377..991036 Helicobacter pylori P12 7010066 YP_002301561.1 CDS HPP12_0929 NC_011498.1 991040 991642 D hypothetical protein 991040..991642 Helicobacter pylori P12 7010067 YP_002301562.1 CDS HPP12_0930 NC_011498.1 991645 992400 D radical SAM domain-containing protein 991645..992400 Helicobacter pylori P12 7010068 YP_002301563.1 CDS HPP12_0931 NC_011498.1 992411 992896 D hypothetical protein 992411..992896 Helicobacter pylori P12 7010069 YP_002301564.1 CDS HPP12_0932 NC_011498.1 992995 993336 D outer membrane protein HomA-like fragment; hypothetical protein 992995..993336 Helicobacter pylori P12 7010070 YP_002301565.1 CDS proP NC_011498.1 993361 994533 R proline and betaine transporter complement(993361..994533) Helicobacter pylori P12 7010071 YP_002301566.1 CDS HPP12_0934 NC_011498.1 995005 995391 R hypothetical protein complement(995005..995391) Helicobacter pylori P12 7010072 YP_002301567.1 CDS HPP12_0935 NC_011498.1 995339 996337 R hypothetical protein complement(995339..996337) Helicobacter pylori P12 7010073 YP_002301568.1 CDS HPP12_0936 NC_011498.1 996760 997473 R permease protein; amino acid ABC transporter complement(996760..997473) Helicobacter pylori P12 7010074 YP_002301569.1 CDS HPP12_0937 NC_011498.1 997457 998161 R periplasmic binding protein; amino acid ABC transporter complement(997457..998161) Helicobacter pylori P12 7010075 YP_002301570.1 CDS alr NC_011498.1 998296 999429 R alanine racemase complement(998296..999429) Helicobacter pylori P12 7010076 YP_002301571.1 CDS HPP12_0939 NC_011498.1 999436 1000788 R D-alanine glycine permease complement(999436..1000788) Helicobacter pylori P12 7010077 YP_002301572.1 CDS dadA NC_011498.1 1000829 1002061 R D-amino acid dehydrogenase subunit complement(1000829..1002061) Helicobacter pylori P12 7010078 YP_002301573.1 CDS HPP12_0941 NC_011498.1 1002084 1002461 R translation initiation inhibitor complement(1002084..1002461) Helicobacter pylori P12 7010079 YP_002301574.1 CDS HPP12_0942 NC_011498.1 1003389 1004879 D integral membrane protein 1003389..1004879 Helicobacter pylori P12 7010084 YP_002301575.1 CDS HPP12_0943 NC_011498.1 1005195 1005557 D hypothetical protein 1005195..1005557 Helicobacter pylori P12 7010085 YP_002301576.1 CDS HPP12_0944 NC_011498.1 1005929 1006942 R hypothetical protein complement(1005929..1006942) Helicobacter pylori P12 7010086 YP_002301577.1 CDS HPP12_0945 NC_011498.1 1006952 1007404 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(1006952..1007404) Helicobacter pylori P12 7010087 YP_002301578.1 CDS accD NC_011498.1 1007418 1008287 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(1007418..1008287) Helicobacter pylori P12 7010088 YP_002301579.1 CDS HPP12_0947 NC_011498.1 1008368 1008982 D putative recombination protein RecO 1008368..1008982 Helicobacter pylori P12 7010089 YP_002301580.1 CDS HPP12_0948 NC_011498.1 1008993 1009649 D integral membrane protein 1008993..1009649 Helicobacter pylori P12 7010090 YP_002301581.1 CDS HPP12_0949 NC_011498.1 1009652 1010218 R hypothetical protein complement(1009652..1010218) Helicobacter pylori P12 7010091 YP_002301582.1 CDS HPP12_0950 NC_011498.1 1010283 1010915 R oxygen-insensitive NADPH nitroreductase complement(1010283..1010915) Helicobacter pylori P12 7010092 YP_002301583.1 CDS lgt NC_011498.1 1010912 1011766 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1010912..1011766) Helicobacter pylori P12 7010093 YP_002301584.1 CDS HPP12_0952 NC_011498.1 1011776 1012504 R ribosomal large subunit pseudouridine synthase C complement(1011776..1012504) Helicobacter pylori P12 7010094 YP_002301585.1 CDS HPP12_0953 NC_011498.1 1012523 1013704 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(1012523..1013704) Helicobacter pylori P12 7010095 YP_002301586.1 CDS HPP12_0954 NC_011498.1 1013705 1014484 R hypothetical protein complement(1013705..1014484) Helicobacter pylori P12 7010096 YP_002301587.1 CDS HPP12_0955 NC_011498.1 1014494 1015225 R hypothetical protein complement(1014494..1015225) Helicobacter pylori P12 7010097 YP_002301588.1 CDS glyQ NC_011498.1 1015227 1016123 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1015227..1016123) Helicobacter pylori P12 7010098 YP_002301589.1 CDS gpsA NC_011498.1 1016137 1017075 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(1016137..1017075) Helicobacter pylori P12 7010099 YP_002301590.1 CDS HPP12_0958 NC_011498.1 1017216 1018976 R hypothetical protein complement(1017216..1018976) Helicobacter pylori P12 7010100 YP_002301591.1 CDS HPP12_0959 NC_011498.1 1018976 1019368 R ATP/GTP-binding protein complement(1018976..1019368) Helicobacter pylori P12 7010101 YP_002301592.1 CDS HPP12_0960 NC_011498.1 1019341 1021305 R ATP/GTP-binding protein complement(1019341..1021305) Helicobacter pylori P12 7010102 YP_002301593.1 CDS HPP12_0961 NC_011498.1 1021307 1022623 R hypothetical protein complement(1021307..1022623) Helicobacter pylori P12 7010103 YP_002301594.1 CDS HPP12_0962 NC_011498.1 1022703 1022954 R hypothetical protein complement(1022703..1022954) Helicobacter pylori P12 7010104 YP_002301595.1 CDS vapD NC_011498.1 1023165 1023452 R virulence associated protein D complement(1023165..1023452) Helicobacter pylori P12 7010105 YP_002301596.1 CDS HPP12_0964 NC_011498.1 1023522 1023803 R hypothetical protein complement(1023522..1023803) Helicobacter pylori P12 7010106 YP_002301597.1 CDS HPP12_0965 NC_011498.1 1023819 1026878 R cation efflux system protein; cobalt-zinc-cadmium resistance protein complement(1023819..1026878) Helicobacter pylori P12 7010107 YP_002301598.1 CDS HPP12_0966 NC_011498.1 1026878 1027957 R cation efflux system protein; cobalt-zinc-cadmium resistance protein complement(1026878..1027957) Helicobacter pylori P12 7010108 YP_002301599.1 CDS HPP12_0967 NC_011498.1 1027954 1029249 R nickel cobalt outer membrane efflux protein complement(1027954..1029249) Helicobacter pylori P12 7010109 YP_002301600.1 CDS glyS NC_011498.1 1029239 1031344 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1029239..1031344) Helicobacter pylori P12 7010110 YP_002301601.1 CDS HPP12_0969 NC_011498.1 1031457 1032530 D hypothetical protein 1031457..1032530 Helicobacter pylori P12 7010111 YP_002301602.1 CDS pgm NC_011498.1 1032543 1034018 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1032543..1034018 Helicobacter pylori P12 7010112 YP_002301603.1 CDS gatC NC_011498.1 1034033 1034314 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1034033..1034314 Helicobacter pylori P12 7010113 YP_002301604.1 CDS bioA NC_011498.1 1034434 1035744 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(1034434..1035744) Helicobacter pylori P12 7010114 YP_002301605.1 CDS HPP12_0973 NC_011498.1 1035874 1037337 D peptidyl-prolyl cis-trans isomerase D 1035874..1037337 Helicobacter pylori P12 7010115 YP_002301606.1 CDS ftsA NC_011498.1 1037353 1038831 D cell division protein FtsA 1037353..1038831 Helicobacter pylori P12 7010116 YP_002301607.1 CDS ftsZ NC_011498.1 1038962 1040119 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1038962..1040119 Helicobacter pylori P12 7010117 YP_002301608.1 CDS HPP12_0976 NC_011498.1 1040198 1040341 R hypothetical protein complement(1040198..1040341) Helicobacter pylori P12 7010118 YP_002301609.1 CDS HPP12_0977 NC_011498.1 1040472 1041137 R hypothetical protein complement(1040472..1041137) Helicobacter pylori P12 7010119 YP_002301610.1 CDS HPP12_0978 NC_011498.1 1041309 1041845 R hypothetical protein complement(1041309..1041845) Helicobacter pylori P12 7010120 YP_002301611.1 CDS HPP12_0979 NC_011498.1 1042008 1042832 R mechanosensitive ion channel domain-containing protein complement(1042008..1042832) Helicobacter pylori P12 7010121 YP_002301612.1 CDS HPP12_0980 NC_011498.1 1043356 1044480 R hypothetical protein complement(1043356..1044480) Helicobacter pylori P12 7010122 YP_002301613.1 CDS HPP12_0981 NC_011498.1 1044484 1044765 R hypothetical protein complement(1044484..1044765) Helicobacter pylori P12 7010123 YP_002301614.1 CDS HPP12_0982 NC_011498.1 1045061 1046974 R hypothetical protein complement(1045061..1046974) Helicobacter pylori P12 7010124 YP_002301615.1 CDS HPP12_0983 NC_011498.1 1047017 1047751 R hypothetical protein complement(1047017..1047751) Helicobacter pylori P12 7010125 YP_002301616.1 CDS HPP12_0984 NC_011498.1 1047885 1049291 R hypothetical protein complement(1047885..1049291) Helicobacter pylori P12 7010126 YP_002301617.1 CDS HPP12_0985 NC_011498.1 1049357 1049623 R hypothetical protein complement(1049357..1049623) Helicobacter pylori P12 7010127 YP_002301618.1 CDS HPP12_0986 NC_011498.1 1049671 1049991 R hypothetical protein complement(1049671..1049991) Helicobacter pylori P12 7010128 YP_002301619.1 CDS HPP12_0987 NC_011498.1 1050030 1050701 R hypothetical protein complement(1050030..1050701) Helicobacter pylori P12 7010129 YP_002301620.1 CDS HPP12_0988 NC_011498.1 1050711 1050881 R hypothetical protein complement(1050711..1050881) Helicobacter pylori P12 7010130 YP_002301621.1 CDS HPP12_0989 NC_011498.1 1050977 1051564 R serine/threonine kinase C-like protein complement(1050977..1051564) Helicobacter pylori P12 7010131 YP_002301622.1 CDS HPP12_0990 NC_011498.1 1051604 1052053 R serine/threonine kinase C-like protein complement(1051604..1052053) Helicobacter pylori P12 7010132 YP_002301623.1 CDS HPP12_0991 NC_011498.1 1052213 1052728 R serine/threonine phosphatase 2C-like protein complement(1052213..1052728) Helicobacter pylori P12 7010133 YP_002301624.1 CDS HPP12_0992 NC_011498.1 1052725 1052973 R hypothetical protein complement(1052725..1052973) Helicobacter pylori P12 7010134 YP_002301625.1 CDS terY NC_011498.1 1053140 1053784 R phage/colicin/tellurite resistance cluster protein TerY complement(1053140..1053784) Helicobacter pylori P12 7010135 YP_002301626.1 CDS HPP12_0994 NC_011498.1 1053794 1053949 R hypothetical protein complement(1053794..1053949) Helicobacter pylori P12 7010136 YP_002301627.1 CDS HPP12_0995 NC_011498.1 1058077 1058427 D hypothetical protein 1058077..1058427 Helicobacter pylori P12 7010139 YP_002301628.1 CDS HPP12_0996 NC_011498.1 1058480 1060213 D hypothetical protein 1058480..1060213 Helicobacter pylori P12 7010140 YP_002301629.1 CDS HPP12_0997 NC_011498.1 1060255 1061508 D hypothetical protein 1060255..1061508 Helicobacter pylori P12 7010141 YP_002301630.1 CDS HPP12_0998 NC_011498.1 1061552 1061683 D hypothetical protein 1061552..1061683 Helicobacter pylori P12 7010142 YP_002301631.1 CDS HPP12_0999 NC_011498.1 1061807 1063411 D hypothetical protein 1061807..1063411 Helicobacter pylori P12 7010143 YP_002301632.1 CDS HPP12_1000 NC_011498.1 1063516 1064145 D hypothetical protein 1063516..1064145 Helicobacter pylori P12 7010144 YP_002301633.1 CDS HPP12_1001 NC_011498.1 1064130 1064426 D hypothetical protein 1064130..1064426 Helicobacter pylori P12 7010145 YP_002301634.1 CDS speA NC_011498.1 1064516 1066363 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(1064516..1066363) Helicobacter pylori P12 7010146 YP_002301635.1 CDS capJ NC_011498.1 1066377 1067546 R type 1 capsular polysaccharide biosynthesis protein J complement(1066377..1067546) Helicobacter pylori P12 7010147 YP_002301636.1 CDS HPP12_1004 NC_011498.1 1067551 1067979 R hypothetical protein complement(1067551..1067979) Helicobacter pylori P12 7010148 YP_002301637.1 CDS HPP12_1005 NC_011498.1 1068000 1068785 R S-adenosylmethionine-dependent methyltransferase complement(1068000..1068785) Helicobacter pylori P12 7010149 YP_002301638.1 CDS HPP12_1006 NC_011498.1 1068789 1069808 R hypothetical protein complement(1068789..1069808) Helicobacter pylori P12 7010150 YP_002301639.1 CDS metG NC_011498.1 1069809 1071761 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1069809..1071761) Helicobacter pylori P12 7010151 YP_002301640.1 CDS cfa NC_011498.1 1071930 1073099 D cyclopropane fatty acid synthase 1071930..1073099 Helicobacter pylori P12 7010152 YP_002301641.1 CDS HPP12_1009 NC_011498.1 1073102 1074973 R mechanosensitive ion channel family protein complement(1073102..1074973) Helicobacter pylori P12 7010153 YP_002301642.1 CDS HPP12_1010 NC_011498.1 1076208 1076960 R flagellar sheath adhesin complement(1076208..1076960) Helicobacter pylori P12 7010158 YP_002301643.1 CDS guaA NC_011498.1 1077045 1078571 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1077045..1078571) Helicobacter pylori P12 7010159 YP_002301644.1 CDS HPP12_1012 NC_011498.1 1078582 1079070 R hypothetical protein complement(1078582..1079070) Helicobacter pylori P12 7010160 YP_002301645.1 CDS HPP12_1013 NC_011498.1 1079237 1081627 R biotin sulfoxide reductase complement(1079237..1081627) Helicobacter pylori P12 7010161 YP_002301646.1 CDS HPP12_1014 NC_011498.1 1081731 1082321 R hypothetical protein complement(1081731..1082321) Helicobacter pylori P12 7010162 YP_002301647.1 CDS HPP12_1015 NC_011498.1 1082347 1083669 R nifs-like protein complement(1082347..1083669) Helicobacter pylori P12 7010163 YP_002301648.1 CDS HPP12_1016 NC_011498.1 1083688 1084002 R ADP hydrolase of the hit protein family complement(1083688..1084002) Helicobacter pylori P12 7010164 YP_002301649.1 CDS pheS NC_011498.1 1084083 1085069 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1084083..1085069 Helicobacter pylori P12 7010165 YP_002301650.1 CDS pheT NC_011498.1 1085069 1087363 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1085069..1087363 Helicobacter pylori P12 7010166 YP_002301651.1 CDS aroA NC_011498.1 1087379 1088668 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1087379..1088668 Helicobacter pylori P12 7010167 YP_002301652.1 CDS ispH NC_011498.1 1088658 1089482 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1088658..1089482 Helicobacter pylori P12 7010168 YP_002301653.1 CDS rpsA NC_011498.1 1089603 1091273 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1089603..1091273 Helicobacter pylori P12 7010169 YP_002301654.1 CDS HPP12_1022 NC_011498.1 1091302 1091832 D hypothetical protein 1091302..1091832 Helicobacter pylori P12 7010170 YP_002301655.1 CDS serA NC_011498.1 1091848 1093422 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1091848..1093422 Helicobacter pylori P12 7010171 YP_002301656.1 CDS HPP12_1024 NC_011498.1 1093432 1095282 D 3-octaprenyl-4-hydroxybenzoate carboxylyase 1093432..1095282 Helicobacter pylori P12 7010172 YP_002301657.1 CDS HPP12_1025 NC_011498.1 1095305 1095973 D hypothetical protein 1095305..1095973 Helicobacter pylori P12 7010173 YP_002301658.1 CDS HPP12_1026 NC_011498.1 1095975 1096733 D hypothetical protein 1095975..1096733 Helicobacter pylori P12 7010174 YP_002301659.1 CDS cheV-3 NC_011498.1 1096737 1097672 D CheA-MCP interaction modulator; chemotaxis protein 1096737..1097672 Helicobacter pylori P12 7010175 YP_002301660.1 CDS cheA NC_011498.1 1097729 1100146 D autophosphorylating histidine kinase 1097729..1100146 Helicobacter pylori P12 7010176 YP_002301661.1 CDS cheW NC_011498.1 1100143 1100640 D purine-binding chemotaxis protein/Chea-MCP coupling protein 1100143..1100640 Helicobacter pylori P12 7010177 YP_002301662.1 CDS HPP12_1030 NC_011498.1 1100894 1101394 R thiol peroxidase complement(1100894..1101394) Helicobacter pylori P12 7010178 YP_002301663.1 CDS HPP12_1031 NC_011498.1 1101618 1102259 D iron-dependent superoxide dismutase 1101618..1102259 Helicobacter pylori P12 7010179 YP_002301664.1 CDS HPP12_1032 NC_011498.1 1102314 1103045 D methyltransferase 1102314..1103045 Helicobacter pylori P12 7010180 YP_002301665.1 CDS priA NC_011498.1 1103107 1104966 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1103107..1104966) Helicobacter pylori P12 7010181 YP_002301666.1 CDS HPP12_1034 NC_011498.1 1104951 1105187 R hypothetical protein complement(1104951..1105187) Helicobacter pylori P12 7010182 YP_002301667.1 CDS HPP12_1035 NC_011498.1 1105200 1105427 R hypothetical protein complement(1105200..1105427) Helicobacter pylori P12 7010183 YP_002301668.1 CDS HPP12_1036 NC_011498.1 1105630 1106376 D hypothetical protein 1105630..1106376 Helicobacter pylori P12 7010184 YP_002301669.1 CDS HPP12_1037 NC_011498.1 1106384 1106914 R hypothetical protein complement(1106384..1106914) Helicobacter pylori P12 7010185 YP_002301670.1 CDS HPP12_1038 NC_011498.1 1106880 1107014 D hypothetical protein 1106880..1107014 Helicobacter pylori P12 7010186 YP_002301671.1 CDS HPP12_1039 NC_011498.1 1107093 1108223 D zinc-metalloprotease 1107093..1108223 Helicobacter pylori P12 7010187 YP_002301672.1 CDS hemK NC_011498.1 1108220 1109050 D S-adenosylmethionine-dependent methyltransferase 1108220..1109050 Helicobacter pylori P12 7010188 YP_002301673.1 CDS gdhA NC_011498.1 1109117 1110463 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1109117..1110463 Helicobacter pylori P12 7010189 YP_002301674.1 CDS HPP12_1042 NC_011498.1 1110477 1111781 R alpha-1,3-fucosyltransferase complement(1110477..1111781) Helicobacter pylori P12 7010190 YP_002301675.1 CDS HPP12_1043 NC_011498.1 1111791 1114601 R cytochrome C-type biogenesis protein complement(1111791..1114601) Helicobacter pylori P12 7010191 YP_002301676.1 CDS HPP12_1044 NC_011498.1 1114610 1115281 R thiol:disulfide interchange protein complement(1114610..1115281) Helicobacter pylori P12 7010192 YP_002301677.1 CDS hemH NC_011498.1 1115358 1116362 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1115358..1116362) Helicobacter pylori P12 7010193 YP_002301678.1 CDS HPP12_1046 NC_011498.1 1116418 1116849 D hypothetical protein 1116418..1116849 Helicobacter pylori P12 7010194 YP_002301679.1 CDS HPP12_1047 NC_011498.1 1116850 1117530 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1116850..1117530 Helicobacter pylori P12 7010195 YP_002301680.1 CDS homC NC_011498.1 1117554 1119662 R outer membrane protein HomC complement(1117554..1119662) Helicobacter pylori P12 7010196 YP_002301681.1 CDS dcd NC_011498.1 1119823 1120389 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(1119823..1120389) Helicobacter pylori P12 7010197 YP_002301682.1 CDS HPP12_1050 NC_011498.1 1120520 1120990 D biotin carboxyl carrier protein 1120520..1120990 Helicobacter pylori P12 7010198 YP_002301683.1 CDS HPP12_1051 NC_011498.1 1120996 1122375 D biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1120996..1122375 Helicobacter pylori P12 7010199 YP_002301684.1 CDS HPP12_1052 NC_011498.1 1122468 1123430 D type II R-M system methyltransferase 1122468..1123430 Helicobacter pylori P12 7010200 YP_002301685.1 CDS HPP12_1053 NC_011498.1 1123430 1123978 D type II R-M system restriction endonuclease 1123430..1123978 Helicobacter pylori P12 7010201 YP_002301686.1 CDS HPP12_1054 NC_011498.1 1124071 1124670 D hypothetical protein 1124071..1124670 Helicobacter pylori P12 7010202 YP_002301687.1 CDS HPP12_1055 NC_011498.1 1124667 1125794 D involved in pseudaminic acid biosynthesis; aminotransferase 1124667..1125794 Helicobacter pylori P12 7010203 YP_002301688.1 CDS nrdF NC_011498.1 1126116 1127141 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1126116..1127141 Helicobacter pylori P12 7010205 YP_002301689.1 CDS pcm NC_011498.1 1127151 1127780 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1127151..1127780 Helicobacter pylori P12 7010206 YP_002301690.1 CDS HPP12_1058 NC_011498.1 1127791 1128828 D integral membrane protein 1127791..1128828 Helicobacter pylori P12 7010207 YP_002301691.1 CDS truA NC_011498.1 1128830 1129558 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1128830..1129558 Helicobacter pylori P12 7010208 YP_002301692.1 CDS galE NC_011498.1 1129552 1130586 R UDP-glucose 4-epimerase complement(1129552..1130586) Helicobacter pylori P12 7010209 YP_002301693.1 CDS HPP12_1061 NC_011498.1 1131284 1132819 D outer membrane protein 1131284..1132819 Helicobacter pylori P12 7010212 YP_002301694.1 CDS HPP12_1062 NC_011498.1 1132837 1133589 D short chain alcohol dehydrogenase 1132837..1133589 Helicobacter pylori P12 7010213 YP_002301695.1 CDS hcpC NC_011498.1 1133806 1134678 R cysteine-rich protein C complement(1133806..1134678) Helicobacter pylori P12 7010214 YP_002301696.1 CDS eda NC_011498.1 1134753 1135373 R 2-keto-3-deoxy-6-phosphogluconate aldolase complement(1134753..1135373) Helicobacter pylori P12 7010215 YP_002301697.1 CDS edd NC_011498.1 1135392 1137218 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1135392..1137218) Helicobacter pylori P12 7010216 YP_002301698.1 CDS HPP12_1066 NC_011498.1 1137284 1138561 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1137284..1138561 Helicobacter pylori P12 7010217 YP_002301699.1 CDS HPP12_1067 NC_011498.1 1138572 1139255 D glucose-6-phosphate 1-dehydrogenase 1138572..1139255 Helicobacter pylori P12 7010218 YP_002301700.1 CDS glk NC_011498.1 1139242 1140252 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1139242..1140252 Helicobacter pylori P12 7010219 YP_002301701.1 CDS HPP12_1069 NC_011498.1 1140422 1141468 D mannitol dehydrogenase 1140422..1141468 Helicobacter pylori P12 7010220 YP_002301702.1 CDS HPP12_1070 NC_011498.1 1141478 1142674 R lipopolysaccharide biosynthesis protein complement(1141478..1142674) Helicobacter pylori P12 7010221 YP_002301703.1 CDS HPP12_1071 NC_011498.1 1142848 1144155 D hypothetical protein 1142848..1144155 Helicobacter pylori P12 7010222 YP_002301704.1 CDS horH NC_011498.1 1144162 1144824 R outer membrane protein HorH complement(1144162..1144824) Helicobacter pylori P12 7010223 YP_002301705.1 CDS porG NC_011498.1 1145115 1145675 D pyruvate flavodoxin oxidoreductase subunit gamma 1145115..1145675 Helicobacter pylori P12 7010224 YP_002301706.1 CDS porD NC_011498.1 1145691 1146083 D pyruvate flavodoxin oxidoreductase subunit delta 1145691..1146083 Helicobacter pylori P12 7010225 YP_002301707.1 CDS porA NC_011498.1 1146093 1147316 D pyruvate flavodoxin oxidoreductase subunit alpha 1146093..1147316 Helicobacter pylori P12 7010226 YP_002301708.1 CDS porB NC_011498.1 1147329 1148273 D pyruvate ferredoxin oxidoreductase beta subunit 1147329..1148273 Helicobacter pylori P12 7010227 YP_002301709.1 CDS purB NC_011498.1 1148381 1149703 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1148381..1149703 Helicobacter pylori P12 7010228 YP_002301710.1 CDS horI NC_011498.1 1149774 1150607 D outer membrane protein HorI 1149774..1150607 Helicobacter pylori P12 7010229 YP_002301711.1 CDS uvrB NC_011498.1 1150604 1152580 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1150604..1152580) Helicobacter pylori P12 7010230 YP_002301712.1 CDS HPP12_1080 NC_011498.1 1152621 1153301 R hypothetical protein complement(1152621..1153301) Helicobacter pylori P12 7010231 YP_002301713.1 CDS HPP12_1081 NC_011498.1 1153314 1156076 R hypothetical protein complement(1153314..1156076) Helicobacter pylori P12 7010232 YP_002301714.1 CDS hcpX NC_011498.1 1156483 1157253 R cysteine-rich protein X complement(1156483..1157253) Helicobacter pylori P12 7010233 YP_002301715.1 CDS ggt NC_011498.1 1157491 1159194 R gamma-glutamyltranspeptidase complement(1157491..1159194) Helicobacter pylori P12 7010234 YP_002301716.1 CDS flgK NC_011498.1 1159371 1161191 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(1159371..1161191) Helicobacter pylori P12 7010235 YP_002301717.1 CDS HPP12_1085 NC_011498.1 1161193 1161627 R hypothetical protein complement(1161193..1161627) Helicobacter pylori P12 7010236 YP_002301718.1 CDS HPP12_1086 NC_011498.1 1161706 1162458 R type II R-M system restriction endonuclease complement(1161706..1162458) Helicobacter pylori P12 7010237 YP_002301719.1 CDS HPP12_1087 NC_011498.1 1162451 1163398 R type II R-M system methyltransferase complement(1162451..1163398) Helicobacter pylori P12 7010238 YP_002301720.1 CDS flgM NC_011498.1 1163561 1163764 R FlgM protein complement(1163561..1163764) Helicobacter pylori P12 7010239 YP_002301721.1 CDS HPP12_1089 NC_011498.1 1163828 1164034 R hypothetical protein complement(1163828..1164034) Helicobacter pylori P12 7010240 YP_002301722.1 CDS slyD NC_011498.1 1164066 1164623 R fkbp-type peptidyl-prolyl cis-trans isomerase complement(1164066..1164623) Helicobacter pylori P12 7010241 YP_002301723.1 CDS HPP12_1091 NC_011498.1 1164610 1165605 R hypothetical protein complement(1164610..1165605) Helicobacter pylori P12 7010242 YP_002301724.1 CDS HPP12_1092 NC_011498.1 1165613 1166152 R peptidoglycan-associated lipoprotein precursor complement(1165613..1166152) Helicobacter pylori P12 7010243 YP_002301725.1 CDS tolB NC_011498.1 1166219 1167472 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(1166219..1167472) Helicobacter pylori P12 7010244 YP_002301726.1 CDS HPP12_1094 NC_011498.1 1167469 1168305 R hypothetical protein complement(1167469..1168305) Helicobacter pylori P12 7010245 YP_002301727.1 CDS exbD-1 NC_011498.1 1168324 1168725 R biopolymer transport accessory protein ExbD complement(1168324..1168725) Helicobacter pylori P12 7010246 YP_002301728.1 CDS exbB-1 NC_011498.1 1168778 1169347 R biopolymer transport accessory protein ExbB complement(1168778..1169347) Helicobacter pylori P12 7010247 YP_002301729.1 CDS atpC NC_011498.1 1169358 1169729 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1169358..1169729) Helicobacter pylori P12 7010248 YP_002301730.1 CDS HPP12_1098 NC_011498.1 1169740 1171149 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1169740..1171149) Helicobacter pylori P12 7010249 YP_002301731.1 CDS HPP12_1099 NC_011498.1 1171173 1172078 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1171173..1172078) Helicobacter pylori P12 7010250 YP_002301732.1 CDS HPP12_1100 NC_011498.1 1172093 1173604 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1172093..1173604) Helicobacter pylori P12 7010251 YP_002301733.1 CDS HPP12_1101 NC_011498.1 1173627 1174169 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1173627..1174169) Helicobacter pylori P12 7010252 YP_002301734.1 CDS HPP12_1102 NC_011498.1 1174170 1174685 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1174170..1174685) Helicobacter pylori P12 7010253 YP_002301735.1 CDS HPP12_1103 NC_011498.1 1174689 1175123 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' complement(1174689..1175123) Helicobacter pylori P12 7010254 YP_002301736.1 CDS spo0J NC_011498.1 1175233 1176105 R chromosome partitioning protein complement(1175233..1176105) Helicobacter pylori P12 7010255 YP_002301737.1 CDS soj NC_011498.1 1176109 1176903 R chromosome partitioning protein complement(1176109..1176903) Helicobacter pylori P12 7010256 YP_002301738.1 CDS HPP12_1106 NC_011498.1 1176906 1177544 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(1176906..1177544) Helicobacter pylori P12 7010257 YP_002301739.1 CDS fmt NC_011498.1 1177541 1178458 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1177541..1178458) Helicobacter pylori P12 7010258 YP_002301740.1 CDS HPP12_1108 NC_011498.1 1178460 1181081 R involved in DNA repair; ATPase complement(1178460..1181081) Helicobacter pylori P12 7010259 YP_002301741.1 CDS HPP12_1109 NC_011498.1 1181126 1182427 R hypothetical protein complement(1181126..1182427) Helicobacter pylori P12 7010260 YP_002301742.1 CDS HPP12_1110 NC_011498.1 1182635 1183066 D hypothetical protein 1182635..1183066 Helicobacter pylori P12 7010261 YP_002301743.1 CDS HPP12_1111 NC_011498.1 1185649 1186536 R hypothetical protein complement(1185649..1186536) Helicobacter pylori P12 7010263 YP_002301744.1 CDS HPP12_1112 NC_011498.1 1186680 1186829 D hypothetical protein 1186680..1186829 Helicobacter pylori P12 7010264 YP_002301745.1 CDS rplS NC_011498.1 1186826 1187182 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1186826..1187182) Helicobacter pylori P12 7010265 YP_002301746.1 CDS trmD NC_011498.1 1187204 1187893 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1187204..1187893) Helicobacter pylori P12 7010266 YP_002301747.1 CDS rimM NC_011498.1 1187894 1188448 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1187894..1188448) Helicobacter pylori P12 7010267 YP_002301748.1 CDS HPP12_1116 NC_011498.1 1188449 1188796 R hypothetical protein complement(1188449..1188796) Helicobacter pylori P12 7010268 YP_002301749.1 CDS rpsP NC_011498.1 1188813 1189043 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1188813..1189043) Helicobacter pylori P12 7010269 YP_002301750.1 CDS ffh NC_011498.1 1189117 1190463 R signal recognition particle protein complement(1189117..1190463) Helicobacter pylori P12 7010270 YP_002301751.1 CDS valS NC_011498.1 1190478 1193096 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1190478..1193096) Helicobacter pylori P12 7010271 YP_002301752.1 CDS fliW-1 NC_011498.1 1193233 1193640 D binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1193233..1193640 Helicobacter pylori P12 7010272 YP_002301753.1 CDS murG NC_011498.1 1193652 1194713 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1193652..1194713 Helicobacter pylori P12 7010273 YP_002301754.1 CDS hopI NC_011498.1 1194821 1196911 D outer membrane protein HopI 1194821..1196911 Helicobacter pylori P12 7010274 YP_002301755.1 CDS hopL NC_011498.1 1196934 1200635 D outer membrane protein HopL 1196934..1200635 Helicobacter pylori P12 7010275 YP_002301756.1 CDS proC NC_011498.1 1200649 1201422 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1200649..1201422 Helicobacter pylori P12 7010276 YP_002301757.1 CDS fic NC_011498.1 1201450 1201983 D cell filamentation protein Fic 1201450..1201983 Helicobacter pylori P12 7010277 YP_002301758.1 CDS HPP12_1126 NC_011498.1 1202074 1202496 R putative metalloprotease complement(1202074..1202496) Helicobacter pylori P12 7010278 YP_002301759.1 CDS fldA NC_011498.1 1202550 1203044 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(1202550..1203044) Helicobacter pylori P12 7010279 YP_002301760.1 CDS HPP12_1128 NC_011498.1 1203136 1203717 R integral membrane protein complement(1203136..1203717) Helicobacter pylori P12 7010280 YP_002301761.1 CDS HPP12_1129 NC_011498.1 1203841 1204032 D cation transport subunit for cbb3-type oxidase 1203841..1204032 Helicobacter pylori P12 7010281 YP_002301762.1 CDS trxB-2 NC_011498.1 1204058 1205026 D thioredoxin reductase family protein 1204058..1205026 Helicobacter pylori P12 7010282 YP_002301763.1 CDS HPP12_1131 NC_011498.1 1205224 1206384 R major facilitator superfamily permease complement(1205224..1206384) Helicobacter pylori P12 7010283 YP_002301764.1 CDS pgi NC_011498.1 1206447 1208084 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1206447..1208084 Helicobacter pylori P12 7010284 YP_002301765.1 CDS hofH NC_011498.1 1208392 1209807 D outer membrane protein HofH 1208392..1209807 Helicobacter pylori P12 7010285 YP_002301766.1 CDS HPP12_1134 NC_011498.1 1210204 1212258 R carbon starvation protein A complement(1210204..1212258) Helicobacter pylori P12 7010286 YP_002301767.1 CDS HPP12_1135 NC_011498.1 1212467 1213120 D glutamine ABC transporter permease protein 1212467..1213120 Helicobacter pylori P12 7010287 YP_002301768.1 CDS glnP NC_011498.1 1213123 1213794 D glutamine ABC transporter permease protein 1213123..1213794 Helicobacter pylori P12 7010288 YP_002301769.1 CDS glnQ NC_011498.1 1213796 1214542 D glutamine ABC transporter ATP-binding protein 1213796..1214542 Helicobacter pylori P12 7010289 YP_002301770.1 CDS HPP12_1138 NC_011498.1 1214591 1215424 D glutamine ABC transporter periplasmic glutamine-binding protein 1214591..1215424 Helicobacter pylori P12 7010290 YP_002301771.1 CDS HPP12_1139 NC_011498.1 1215546 1216097 D hypothetical protein 1215546..1216097 Helicobacter pylori P12 7010291 YP_002301772.1 CDS HPP12_1140 NC_011498.1 1216402 1217625 R glucose/galactose transporter complement(1216402..1217625) Helicobacter pylori P12 7010292 YP_002301773.1 CDS HPP12_1141 NC_011498.1 1217754 1219061 R integral membrane protein complement(1217754..1219061) Helicobacter pylori P12 7010293 YP_002301774.1 CDS hopQ NC_011498.1 1219541 1221469 R outer membrane protein HopQ complement(1219541..1221469) Helicobacter pylori P12 7010294 YP_002301775.1 CDS deoD NC_011498.1 1221931 1222632 R purine-nucleoside phosphorylase complement(1221931..1222632) Helicobacter pylori P12 7010295 YP_002301776.1 CDS deoB NC_011498.1 1222629 1223870 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1222629..1223870) Helicobacter pylori P12 7010296 YP_002301777.1 CDS nupC NC_011498.1 1223882 1225138 R pyrimidine nucleoside transport protein complement(1223882..1225138) Helicobacter pylori P12 7010297 YP_002301778.1 CDS HPP12_1146 NC_011498.1 1225451 1226782 D multidrug-efflux transporter 1225451..1226782 Helicobacter pylori P12 7010299 YP_002301779.1 CDS HPP12_1147 NC_011498.1 1226801 1227562 D PP-loop family protein 1226801..1227562 Helicobacter pylori P12 7010300 YP_002301780.1 CDS HPP12_1148 NC_011498.1 1227559 1228710 R na+/h+ antiporter complement(1227559..1228710) Helicobacter pylori P12 7010301 YP_002301781.1 CDS HPP12_1149 NC_011498.1 1228736 1230115 R integral membrane protein complement(1228736..1230115) Helicobacter pylori P12 7010302 YP_002301782.1 CDS HPP12_1150 NC_011498.1 1230089 1230223 D hypothetical protein 1230089..1230223 Helicobacter pylori P12 7010303 YP_002301783.1 CDS HPP12_1151 NC_011498.1 1230282 1231457 R sugar efflux transporter complement(1230282..1231457) Helicobacter pylori P12 7010304 YP_002301784.1 CDS HPP12_1152 NC_011498.1 1231729 1232472 D alpha-carbonic anhydrase 1231729..1232472 Helicobacter pylori P12 7010305 YP_002301785.1 CDS HPP12_1153 NC_011498.1 1232713 1233948 R hypothetical protein complement(1232713..1233948) Helicobacter pylori P12 7010306 YP_002301786.1 CDS HPP12_1154 NC_011498.1 1234228 1235298 R hypothetical protein complement(1234228..1235298) Helicobacter pylori P12 7010307 YP_002301787.1 CDS asd NC_011498.1 1235711 1236751 R aspartate-semialdehyde dehydrogenase complement(1235711..1236751) Helicobacter pylori P12 7010308 YP_002301788.1 CDS hisS NC_011498.1 1236738 1238066 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1236738..1238066) Helicobacter pylori P12 7010309 YP_002301789.1 CDS HPP12_1157 NC_011498.1 1238128 1239177 D ADP-heptose-lps-heptosyltransferase II 1238128..1239177 Helicobacter pylori P12 7010310 YP_002301790.1 CDS HPP12_1158 NC_011498.1 1239368 1239697 R hypothetical protein complement(1239368..1239697) Helicobacter pylori P12 7010311 YP_002301791.1 CDS HPP12_1159 NC_011498.1 1239975 1240904 D aldo-keto reductase 1239975..1240904 Helicobacter pylori P12 7010312 YP_002301792.1 CDS fusA NC_011498.1 1241421 1243499 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1241421..1243499) Helicobacter pylori P12 7010313 YP_002301793.1 CDS rpsG NC_011498.1 1243511 1243978 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1243511..1243978) Helicobacter pylori P12 7010314 YP_002301794.1 CDS rpsL NC_011498.1 1243994 1244401 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1243994..1244401) Helicobacter pylori P12 7010315 YP_002301795.1 CDS rpoB NC_011498.1 1244539 1253163 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' complement(1244539..1253163) Helicobacter pylori P12 7010316 YP_002301796.1 CDS rplL NC_011498.1 1253385 1253762 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1253385..1253762) Helicobacter pylori P12 7010317 YP_002301797.1 CDS rplJ NC_011498.1 1253807 1254301 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1253807..1254301) Helicobacter pylori P12 7010318 YP_002301798.1 CDS rplA NC_011498.1 1254410 1255114 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1254410..1255114) Helicobacter pylori P12 7010319 YP_002301799.1 CDS rplK NC_011498.1 1255159 1255584 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1255159..1255584) Helicobacter pylori P12 7010320 YP_002301800.1 CDS nusG NC_011498.1 1255602 1256132 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1255602..1256132) Helicobacter pylori P12 7010321 YP_002301801.1 CDS secE NC_011498.1 1256159 1256338 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1256159..1256338) Helicobacter pylori P12 7010322 YP_002301802.1 CDS HPP12_1170 NC_011498.1 1256786 1257985 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1256786..1257985) Helicobacter pylori P12 7010324 YP_002301803.1 CDS HPP12_1171 NC_011498.1 1258683 1260419 D ABC transporter ATP-binding protein 1258683..1260419 Helicobacter pylori P12 7010329 YP_002301804.1 CDS HPP12_1172 NC_011498.1 1260430 1261098 R hypothetical protein complement(1260430..1261098) Helicobacter pylori P12 7010330 YP_002301805.1 CDS HPP12_1173 NC_011498.1 1261299 1262288 R type II R-M system methyltransferase complement(1261299..1262288) Helicobacter pylori P12 7010331 YP_002301806.1 CDS HPP12_1174 NC_011498.1 1262297 1262683 R type II R-M system restriction endonuclease complement(1262297..1262683) Helicobacter pylori P12 7010332 YP_002301807.1 CDS HPP12_1175 NC_011498.1 1262641 1262991 R type II R-M system restriction endonuclease complement(1262641..1262991) Helicobacter pylori P12 7010333 YP_002301808.1 CDS cysE NC_011498.1 1263079 1263594 R serine acetyltransferase complement(1263079..1263594) Helicobacter pylori P12 7010334 YP_002301809.1 CDS HPP12_1177 NC_011498.1 1264193 1264510 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1264193..1264510) Helicobacter pylori P12 7010337 YP_002301810.1 CDS HPP12_1178 NC_011498.1 1264806 1265912 D hypothetical protein 1264806..1265912 Helicobacter pylori P12 7010338 YP_002301811.1 CDS pnp NC_011498.1 1265965 1268031 R polynucleotide phosphorylase/polyadenylase complement(1265965..1268031) Helicobacter pylori P12 7010339 YP_002301812.1 CDS HPP12_1180 NC_011498.1 1268034 1268738 R hypothetical protein complement(1268034..1268738) Helicobacter pylori P12 7010340 YP_002301813.1 CDS HPP12_1181 NC_011498.1 1268753 1271014 R organic solvent tolerance protein complement(1268753..1271014) Helicobacter pylori P12 7010341 YP_002301814.1 CDS HPP12_1182 NC_011498.1 1271017 1271496 R hypothetical protein complement(1271017..1271496) Helicobacter pylori P12 7010342 YP_002301815.1 CDS purD NC_011498.1 1271545 1272819 R glycinamide ribonucleotide synthetase complement(1271545..1272819) Helicobacter pylori P12 7010343 YP_002301816.1 CDS HPP12_1184 NC_011498.1 1273203 1273583 R hypothetical protein complement(1273203..1273583) Helicobacter pylori P12 7010344 YP_002301817.1 CDS HPP12_1185 NC_011498.1 1273549 1273998 R hypothetical protein complement(1273549..1273998) Helicobacter pylori P12 7010345 YP_002301818.1 CDS HPP12_1186 NC_011498.1 1274441 1275127 R ABC transporter ATP-binding protein complement(1274441..1275127) Helicobacter pylori P12 7010346 YP_002301819.1 CDS HPP12_1187 NC_011498.1 1275121 1275825 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(1275121..1275825) Helicobacter pylori P12 7010347 YP_002301820.1 CDS dld NC_011498.1 1275866 1278706 R D-lactate dehydrogenase complement(1275866..1278706) Helicobacter pylori P12 7010348 YP_002301821.1 CDS HPP12_1189 NC_011498.1 1278778 1279125 D hypothetical protein 1278778..1279125 Helicobacter pylori P12 7010349 YP_002301822.1 CDS hemD NC_011498.1 1279128 1279808 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1279128..1279808 Helicobacter pylori P12 7010350 YP_002301823.1 CDS crcB NC_011498.1 1279855 1280247 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1279855..1280247 Helicobacter pylori P12 7010351 YP_002301824.1 CDS hemN-2 NC_011498.1 1280299 1281336 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1280299..1281336) Helicobacter pylori P12 7010352 YP_002301825.1 CDS HPP12_1193 NC_011498.1 1281432 1281722 D cytochrome C553 1281432..1281722 Helicobacter pylori P12 7010353 YP_002301826.1 CDS mutT NC_011498.1 1281883 1282350 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1281883..1282350 Helicobacter pylori P12 7010354 YP_002301827.1 CDS lysC NC_011498.1 1282352 1283569 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1282352..1283569 Helicobacter pylori P12 7010355 YP_002301828.1 CDS HPP12_1196 NC_011498.1 1283566 1284108 D hypothetical protein 1283566..1284108 Helicobacter pylori P12 7010356 YP_002301829.1 CDS holB NC_011498.1 1284105 1284761 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1284105..1284761 Helicobacter pylori P12 7010357 YP_002301830.1 CDS folP NC_011498.1 1284758 1285900 D dihydropteroate synthase 1284758..1285900 Helicobacter pylori P12 7010358 YP_002301831.1 CDS HPP12_1199 NC_011498.1 1285988 1286449 R hypothetical protein complement(1285988..1286449) Helicobacter pylori P12 7010359 YP_002301832.1 CDS HPP12_1200 NC_011498.1 1286819 1287715 D membrane transport protein 1286819..1287715 Helicobacter pylori P12 7010360 YP_002301833.1 CDS HPP12_1201 NC_011498.1 1287719 1288966 D integral membrane protein 1287719..1288966 Helicobacter pylori P12 7010361 YP_002301834.1 CDS HPP12_1202 NC_011498.1 1289045 1289596 D hypothetical protein 1289045..1289596 Helicobacter pylori P12 7010362 YP_002301835.1 CDS carA NC_011498.1 1289596 1290723 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1289596..1290723 Helicobacter pylori P12 7010363 YP_002301836.1 CDS amiF NC_011498.1 1290890 1291894 D formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 1290890..1291894 Helicobacter pylori P12 7010364 YP_002301837.1 CDS HPP12_1205 NC_011498.1 1292380 1292916 R hypothetical protein complement(1292380..1292916) Helicobacter pylori P12 7010958 YP_002301838.1 CDS HPP12_1206 NC_011498.1 1292969 1293541 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1292969..1293541) Helicobacter pylori P12 7010959 YP_002301839.1 CDS alaS NC_011498.1 1293543 1296086 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1293543..1296086) Helicobacter pylori P12 7010960 YP_002301840.1 CDS HPP12_1208 NC_011498.1 1296206 1296436 D hypothetical protein 1296206..1296436 Helicobacter pylori P12 7010961 YP_002301841.1 CDS babB NC_011498.1 1297039 1299120 R outer membrane protein HopT/BabB complement(1297039..1299120) Helicobacter pylori P12 7010962 YP_002301842.1 CDS rpsR NC_011498.1 1299704 1299961 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1299704..1299961) Helicobacter pylori P12 7010963 YP_002301843.1 CDS ssb NC_011498.1 1299984 1300529 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1299984..1300529) Helicobacter pylori P12 7010964 YP_002301844.1 CDS rpsF NC_011498.1 1300539 1300967 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1300539..1300967) Helicobacter pylori P12 7010965 YP_002301845.1 CDS HPP12_1213 NC_011498.1 1301120 1302142 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(1301120..1302142) Helicobacter pylori P12 7010966 YP_002301846.1 CDS vacB NC_011498.1 1302132 1304066 R 3'-5' exoribonuclease R complement(1302132..1304066) Helicobacter pylori P12 7010967 YP_002301847.1 CDS aroE NC_011498.1 1304066 1304857 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1304066..1304857) Helicobacter pylori P12 7010968 YP_002301848.1 CDS HPP12_1216 NC_011498.1 1304865 1305455 R hypothetical protein complement(1304865..1305455) Helicobacter pylori P12 7010969 YP_002301849.1 CDS HPP12_1217 NC_011498.1 1305464 1306510 R oligopeptide ABC transporter permease protein complement(1305464..1306510) Helicobacter pylori P12 7010970 YP_002301850.1 CDS HPP12_1218 NC_011498.1 1306507 1308291 R oligopeptide ABC transporter periplasmic oligopeptide-binding protein complement(1306507..1308291) Helicobacter pylori P12 7010971 YP_002301851.1 CDS trpS NC_011498.1 1308292 1309272 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1308292..1309272) Helicobacter pylori P12 7010972 YP_002301852.1 CDS bioC NC_011498.1 1309343 1310080 R biotin synthesis protein BioC complement(1309343..1310080) Helicobacter pylori P12 7010973 YP_002301853.1 CDS secG NC_011498.1 1310204 1310809 D preprotein translocase subunit SecG 1310204..1310809 Helicobacter pylori P12 7010974 YP_002301854.1 CDS frr NC_011498.1 1310809 1311366 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1310809..1311366 Helicobacter pylori P12 7010975 YP_002301855.1 CDS pyrE NC_011498.1 1311370 1311975 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1311370..1311975 Helicobacter pylori P12 7010976 YP_002301856.1 CDS HPP12_1224 NC_011498.1 1311965 1312429 D hypothetical protein 1311965..1312429 Helicobacter pylori P12 7010977 YP_002301857.1 CDS HPP12_1225 NC_011498.1 1312426 1313115 D NAD-dependent deacetylase 1312426..1313115 Helicobacter pylori P12 7010978 YP_002301858.1 CDS nuoA NC_011498.1 1313223 1313624 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A 1313223..1313624 Helicobacter pylori P12 7010979 YP_002301859.1 CDS nuoB NC_011498.1 1313624 1314103 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1313624..1314103 Helicobacter pylori P12 7010980 YP_002301860.1 CDS nuoC NC_011498.1 1314103 1314900 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C 1314103..1314900 Helicobacter pylori P12 7010981 YP_002301861.1 CDS nuoD NC_011498.1 1314902 1316131 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1314902..1316131 Helicobacter pylori P12 7010982 YP_002301862.1 CDS nuoE NC_011498.1 1316128 1316358 D NADH-ubiquinone oxidoreductase chain E 1316128..1316358 Helicobacter pylori P12 7010983 YP_002301863.1 CDS nuoF NC_011498.1 1316361 1317341 D NADH-ubiquinone oxidoreductase chain F 1316361..1317341 Helicobacter pylori P12 7010984 YP_002301864.1 CDS nuoG NC_011498.1 1317338 1319872 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1317338..1319872 Helicobacter pylori P12 7010985 YP_002301865.1 CDS nuoH NC_011498.1 1319869 1320858 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1319869..1320858 Helicobacter pylori P12 7010986 YP_002301866.1 CDS nuoI NC_011498.1 1320869 1321531 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1320869..1321531 Helicobacter pylori P12 7010987 YP_002301867.1 CDS nuoJ NC_011498.1 1321524 1322072 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1321524..1322072 Helicobacter pylori P12 7010988 YP_002301868.1 CDS nuoK NC_011498.1 1322069 1322371 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1322069..1322371 Helicobacter pylori P12 7010989 YP_002301869.1 CDS nuoL NC_011498.1 1322374 1324212 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1322374..1324212 Helicobacter pylori P12 7010990 YP_002301870.1 CDS nuoM NC_011498.1 1324216 1325754 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1324216..1325754 Helicobacter pylori P12 7010991 YP_002301871.1 CDS nuoN NC_011498.1 1325741 1327219 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1325741..1327219 Helicobacter pylori P12 7010992 YP_002301872.1 CDS pflA NC_011498.1 1327209 1329614 D paralysed flagella protein 1327209..1329614 Helicobacter pylori P12 7010993 YP_002301873.1 CDS HPP12_1241 NC_011498.1 1329617 1330993 D phosphomannomutase 1329617..1330993 Helicobacter pylori P12 7010994 YP_002301874.1 CDS HPP12_1242 NC_011498.1 1331291 1331578 D hypothetical protein 1331291..1331578 Helicobacter pylori P12 7010995 YP_002301875.1 CDS trpA NC_011498.1 1331809 1332597 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1331809..1332597) Helicobacter pylori P12 7010996 YP_002301876.1 CDS trpB NC_011498.1 1332594 1333775 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1332594..1333775) Helicobacter pylori P12 7010997 YP_002301877.1 CDS trpC NC_011498.1 1333776 1335134 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1333776..1335134) Helicobacter pylori P12 7010998 YP_002301878.1 CDS trpD NC_011498.1 1335127 1336134 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1335127..1336134) Helicobacter pylori P12 7010999 YP_002301879.1 CDS trpG NC_011498.1 1336131 1336715 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1336131..1336715) Helicobacter pylori P12 7011000 YP_002301880.1 CDS trpE NC_011498.1 1336712 1338214 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1336712..1338214) Helicobacter pylori P12 7011001 YP_002301881.1 CDS HPP12_1249 NC_011498.1 1338437 1339894 R hypothetical protein complement(1338437..1339894) Helicobacter pylori P12 7011002 YP_002301882.1 CDS HPP12_1250 NC_011498.1 1339990 1341030 R hypothetical protein complement(1339990..1341030) Helicobacter pylori P12 7011003 YP_002301883.1 CDS HPP12_1251 NC_011498.1 1341100 1341837 R acid phosphatase lipoprotein complement(1341100..1341837) Helicobacter pylori P12 7011004 YP_002301884.1 CDS HPP12_1252 NC_011498.1 1341961 1342623 D hypothetical protein 1341961..1342623 Helicobacter pylori P12 7011005 YP_002301885.1 CDS HPP12_1253 NC_011498.1 1342574 1343065 R transcriptional regulator complement(1342574..1343065) Helicobacter pylori P12 7011006 YP_002301886.1 CDS HPP12_1254 NC_011498.1 1343908 1344279 D hypothetical protein 1343908..1344279 Helicobacter pylori P12 7011007 YP_002301887.1 CDS HPP12_1255 NC_011498.1 1344303 1344788 D hypothetical protein 1344303..1344788 Helicobacter pylori P12 7011008 YP_002301888.1 CDS pnuC NC_011498.1 1344973 1345635 D nicotinamide mononucleotide transporter 1344973..1345635 Helicobacter pylori P12 7011009 YP_002301889.1 CDS HPP12_1257 NC_011498.1 1345623 1346237 D hypothetical protein 1345623..1346237 Helicobacter pylori P12 7011010 YP_002301890.1 CDS rplQ NC_011498.1 1346874 1347224 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1346874..1347224) Helicobacter pylori P12 7011011 YP_002301891.1 CDS rpoA NC_011498.1 1347224 1348258 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1347224..1348258) Helicobacter pylori P12 7011012 YP_002301892.1 CDS rpsD NC_011498.1 1348270 1348896 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1348270..1348896) Helicobacter pylori P12 7011013 YP_002301893.1 CDS rpsK NC_011498.1 1348906 1349301 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1348906..1349301) Helicobacter pylori P12 7011014 YP_002301894.1 CDS rpsM NC_011498.1 1349324 1349686 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1349324..1349686) Helicobacter pylori P12 7011015 YP_002301895.1 CDS infA NC_011498.1 1349882 1350100 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1349882..1350100) Helicobacter pylori P12 7011016 YP_002301896.1 CDS map NC_011498.1 1350100 1350861 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(1350100..1350861) Helicobacter pylori P12 7011017 YP_002301897.1 CDS secY NC_011498.1 1350861 1352123 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1350861..1352123) Helicobacter pylori P12 7011018 YP_002301898.1 CDS rplO NC_011498.1 1352166 1352567 R late assembly protein; 50S ribosomal protein L15 complement(1352166..1352567) Helicobacter pylori P12 7011019 YP_002301899.1 CDS rpsE NC_011498.1 1352585 1353046 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1352585..1353046) Helicobacter pylori P12 7011020 YP_002301900.1 CDS rplR NC_011498.1 1353043 1353399 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1353043..1353399) Helicobacter pylori P12 7011021 YP_002301901.1 CDS rplF NC_011498.1 1353413 1353949 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1353413..1353949) Helicobacter pylori P12 7011022 YP_002301902.1 CDS rpsH NC_011498.1 1353960 1354355 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1353960..1354355) Helicobacter pylori P12 7011023 YP_002301903.1 CDS rplE NC_011498.1 1354562 1355107 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1354562..1355107) Helicobacter pylori P12 7011024 YP_002301904.1 CDS rplX NC_011498.1 1355120 1355341 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1355120..1355341) Helicobacter pylori P12 7011025 YP_002301905.1 CDS rplN NC_011498.1 1355316 1355708 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1355316..1355708) Helicobacter pylori P12 7011026 YP_002301906.1 CDS rpsQ NC_011498.1 1355711 1355971 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1355711..1355971) Helicobacter pylori P12 7011027 YP_002301907.1 CDS rpmC NC_011498.1 1355985 1356185 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1355985..1356185) Helicobacter pylori P12 7011028 YP_002301908.1 CDS rplP NC_011498.1 1356172 1356597 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1356172..1356597) Helicobacter pylori P12 7011029 YP_002301909.1 CDS rpsC NC_011498.1 1356600 1357304 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1356600..1357304) Helicobacter pylori P12 7011030 YP_002301910.1 CDS rplV NC_011498.1 1357308 1357676 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1357308..1357676) Helicobacter pylori P12 7011031 YP_002301911.1 CDS rpsS NC_011498.1 1357686 1357967 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1357686..1357967) Helicobacter pylori P12 7011032 YP_002301912.1 CDS rplB NC_011498.1 1357978 1358808 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1357978..1358808) Helicobacter pylori P12 7011033 YP_002301913.1 CDS rplW NC_011498.1 1358825 1359106 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1358825..1359106) Helicobacter pylori P12 7011034 YP_002301914.1 CDS rplD NC_011498.1 1359110 1359757 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1359110..1359757) Helicobacter pylori P12 7011035 YP_002301915.1 CDS rplC NC_011498.1 1359792 1360367 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1359792..1360367) Helicobacter pylori P12 7011036 YP_002301916.1 CDS rpsJ NC_011498.1 1360404 1360718 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1360404..1360718) Helicobacter pylori P12 7011037 YP_002301917.1 CDS HPP12_1285 NC_011498.1 1360928 1362016 D hypothetical protein 1360928..1362016 Helicobacter pylori P12 7011038 YP_002301918.1 CDS HPP12_1286 NC_011498.1 1362205 1362783 D hypothetical protein 1362205..1362783 Helicobacter pylori P12 7011039 YP_002301919.1 CDS rnhB NC_011498.1 1362757 1363371 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1362757..1363371) Helicobacter pylori P12 7011040 YP_002301920.1 CDS HPP12_1288 NC_011498.1 1363479 1363652 R hypothetical protein complement(1363479..1363652) Helicobacter pylori P12 7011041 YP_002301921.1 CDS fumC NC_011498.1 1363674 1365065 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1363674..1365065) Helicobacter pylori P12 7011042 YP_002301922.1 CDS HPP12_1290 NC_011498.1 1365240 1365617 D hypothetical protein 1365240..1365617 Helicobacter pylori P12 7011043 YP_002301923.1 CDS HPP12_1291 NC_011498.1 1365622 1366860 D hypothetical protein 1365622..1366860 Helicobacter pylori P12 7011044 YP_002301924.1 CDS czcB NC_011498.1 1366857 1367873 D cation efflux system protein; cobalt-zinc-cadmium resistance protein 1366857..1367873 Helicobacter pylori P12 7011045 YP_002301925.1 CDS czcA NC_011498.1 1367874 1370981 D cation efflux system protein; cobalt-zinc-cadmium resistance protein 1367874..1370981 Helicobacter pylori P12 7011046 YP_002301926.1 CDS HPP12_1294 NC_011498.1 1370962 1371318 R branched-chain amino acid transport protein complement(1370962..1371318) Helicobacter pylori P12 7011047 YP_002301927.1 CDS HPP12_1295 NC_011498.1 1371312 1371998 R branched-chain amino acid transport protein complement(1371312..1371998) Helicobacter pylori P12 7011048 YP_002301928.1 CDS dnaJ NC_011498.1 1372009 1373118 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(1372009..1373118) Helicobacter pylori P12 7011049 YP_002301929.1 CDS HPP12_1297 NC_011498.1 1373243 1374379 D hypothetical protein 1373243..1374379 Helicobacter pylori P12 7011050 YP_002301930.1 CDS mnmA NC_011498.1 1374423 1375511 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1374423..1375511) Helicobacter pylori P12 7011051 YP_002301931.1 CDS HPP12_1299 NC_011498.1 1375591 1376352 D hypothetical protein 1375591..1376352 Helicobacter pylori P12 7011052 YP_002301932.1 CDS HPP12_1300 NC_011498.1 1376349 1376873 R nicotinate-nucleotide adenyltransferase complement(1376349..1376873) Helicobacter pylori P12 7011053 YP_002301933.1 CDS HPP12_1301 NC_011498.1 1376857 1377303 R Inhibits transcription at high concentrations of nickel; nickel responsive regulator complement(1376857..1377303) Helicobacter pylori P12 7011054 YP_002301934.1 CDS exbB-2 NC_011498.1 1377628 1378065 D biopolymer transport protein ExbB 1377628..1378065 Helicobacter pylori P12 7011055 YP_002301935.1 CDS exbD-2 NC_011498.1 1378062 1378451 D biopolymer transport protein ExbD 1378062..1378451 Helicobacter pylori P12 7011056 YP_002301936.1 CDS tonB NC_011498.1 1378417 1379277 D siderophore-mediated iron transport protein 1378417..1379277 Helicobacter pylori P12 7011057 YP_002301937.1 CDS hopN NC_011498.1 1379460 1381547 D outer membrane protein HopN 1379460..1381547 Helicobacter pylori P12 7011058 YP_002301938.1 CDS HPP12_1306 NC_011498.1 1381686 1382414 R integral membrane protein complement(1381686..1382414) Helicobacter pylori P12 7011059 YP_002301939.1 CDS corA NC_011498.1 1382421 1383377 R magnesium and cobalt transport protein complement(1382421..1383377) Helicobacter pylori P12 7011060 YP_002301940.1 CDS pgk NC_011498.1 1383393 1384601 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1383393..1384601) Helicobacter pylori P12 7011061 YP_002301941.1 CDS gap NC_011498.1 1384617 1385609 R glyceraldehyde-3-phosphate dehydrogenase complement(1384617..1385609) Helicobacter pylori P12 7011062 YP_002301942.1 CDS ung NC_011498.1 1385698 1386399 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1385698..1386399) Helicobacter pylori P12 7011063 YP_002301943.1 CDS plsC NC_011498.1 1386396 1387112 R 1-acyl-SN-glycerol-3-phosphate acyltransferase complement(1386396..1387112) Helicobacter pylori P12 7011064 YP_002301944.1 CDS HPP12_1312 NC_011498.1 1387099 1388262 R hypothetical protein complement(1387099..1388262) Helicobacter pylori P12 7011065 YP_002301945.1 CDS HPP12_1313 NC_011498.1 1388269 1389633 R carboxyl-terminal protease complement(1388269..1389633) Helicobacter pylori P12 7011066 YP_002301946.1 CDS HPP12_1314 NC_011498.1 1389854 1390261 R type II R-M system restriction endonuclease complement(1389854..1390261) Helicobacter pylori P12 7011067 YP_002301947.1 CDS HPP12_1315 NC_011498.1 1390306 1390851 R hypothetical protein complement(1390306..1390851) Helicobacter pylori P12 7011068 YP_002301948.1 CDS HPP12_1316 NC_011498.1 1390860 1390988 R hypothetical protein complement(1390860..1390988) Helicobacter pylori P12 7011069 YP_002301949.1 CDS HPP12_1317 NC_011498.1 1391041 1391214 R hypothetical protein complement(1391041..1391214) Helicobacter pylori P12 7011070 YP_002301950.1 CDS HPP12_1318 NC_011498.1 1391189 1391668 R adenine specific DNA methyltransferase-like fragment; hypothetical protein complement(1391189..1391668) Helicobacter pylori P12 7011071 YP_002301951.1 CDS HPP12_1320 NC_011498.1 1394833 1395621 D hypothetical protein 1394833..1395621 Helicobacter pylori P12 7011073 YP_002301952.1 CDS HPP12_1321 NC_011498.1 1395624 1395854 D hypothetical protein 1395624..1395854 Helicobacter pylori P12 7011074 YP_002301953.1 CDS HPP12_1322 NC_011498.1 1395847 1396335 D hypothetical protein 1395847..1396335 Helicobacter pylori P12 7011075 YP_002301954.1 CDS virB2-2 NC_011498.1 1396323 1396607 D VirB2 type IV secretion protein 1396323..1396607 Helicobacter pylori P12 7011076 YP_002301955.1 CDS virB3-2 NC_011498.1 1396619 1396882 D VirB3 type IV secretion protein 1396619..1396882 Helicobacter pylori P12 7011077 YP_002301956.1 CDS HPP12_1325 NC_011498.1 1396894 1397130 D hypothetical protein 1396894..1397130 Helicobacter pylori P12 7011078 YP_002301957.1 CDS virB4-2 NC_011498.1 1397130 1399706 D VirB4 type IV secretion ATPase 1397130..1399706 Helicobacter pylori P12 7011079 YP_002301958.1 CDS virB7-2 NC_011498.1 1399703 1399843 D VirB7 type IV secretion protein 1399703..1399843 Helicobacter pylori P12 7011080 YP_002301959.1 CDS virB8-2 NC_011498.1 1399836 1400972 D VirB8 type IV secretion protein 1399836..1400972 Helicobacter pylori P12 7011081 YP_002301960.1 CDS virB9-2 NC_011498.1 1400969 1402624 D VirB9 type IV secretion protein 1400969..1402624 Helicobacter pylori P12 7011082 YP_002301961.1 CDS virB10-2 NC_011498.1 1402591 1403829 D VirB10 type IV secretion protein 1402591..1403829 Helicobacter pylori P12 7011083 YP_002301962.1 CDS HPP12_1331 NC_011498.1 1403813 1405597 D hypothetical protein 1403813..1405597 Helicobacter pylori P12 7011084 YP_002301963.1 CDS HPP12_1332 NC_011498.1 1405501 1406055 D hypothetical protein 1405501..1406055 Helicobacter pylori P12 7011085 YP_002301964.1 CDS HPP12_1333 NC_011498.1 1406068 1407030 D hypothetical protein 1406068..1407030 Helicobacter pylori P12 7011086 YP_002301965.1 CDS HPP12_1334 NC_011498.1 1407047 1407322 D hypothetical protein 1407047..1407322 Helicobacter pylori P12 7011087 YP_002301966.1 CDS virB11-3 NC_011498.1 1407327 1408271 D VirB11 type IV secretion ATPase 1407327..1408271 Helicobacter pylori P12 7011088 YP_002301967.1 CDS HPP12_1336 NC_011498.1 1408268 1408786 D hypothetical protein 1408268..1408786 Helicobacter pylori P12 7011089 YP_002301968.1 CDS virD4-2 NC_011498.1 1408783 1411026 D VirD4 coupling protein 1408783..1411026 Helicobacter pylori P12 7011090 YP_002301969.1 CDS HPP12_1339 NC_011498.1 1413163 1413633 D hypothetical protein 1413163..1413633 Helicobacter pylori P12 7011092 YP_002301970.1 CDS HPP12_1340 NC_011498.1 1413603 1414406 D hypothetical protein 1413603..1414406 Helicobacter pylori P12 7011093 YP_002301971.1 CDS HPP12_1341 NC_011498.1 1414480 1415145 R hypothetical protein complement(1414480..1415145) Helicobacter pylori P12 7011094 YP_002301972.1 CDS HPP12_1342 NC_011498.1 1415123 1415401 R hypothetical protein complement(1415123..1415401) Helicobacter pylori P12 7011095 YP_002301973.1 CDS HPP12_1343 NC_011498.1 1415334 1415765 R hypothetical protein complement(1415334..1415765) Helicobacter pylori P12 7011096 YP_002301974.1 CDS HPP12_1344 NC_011498.1 1415750 1416160 D hypothetical protein 1415750..1416160 Helicobacter pylori P12 7011097 YP_002301975.1 CDS HPP12_1345 NC_011498.1 1416165 1416794 R hypothetical protein complement(1416165..1416794) Helicobacter pylori P12 7011098 YP_002301976.1 CDS HPP12_1346 NC_011498.1 1416897 1417178 R hypothetical protein complement(1416897..1417178) Helicobacter pylori P12 7011099 YP_002301977.1 CDS HPP12_1347 NC_011498.1 1417399 1417788 D hypothetical protein 1417399..1417788 Helicobacter pylori P12 7011100 YP_002301978.1 CDS HPP12_1348 NC_011498.1 1417796 1418086 D hypothetical protein 1417796..1418086 Helicobacter pylori P12 7011101 YP_002301979.1 CDS HPP12_1349 NC_011498.1 1418215 1418466 D hypothetical protein 1418215..1418466 Helicobacter pylori P12 7011102 YP_002301980.1 CDS HPP12_1350 NC_011498.1 1418394 1419248 D hypothetical protein 1418394..1419248 Helicobacter pylori P12 7011103 YP_002301981.1 CDS HPP12_1352 NC_011498.1 1421131 1421259 D hypothetical protein 1421131..1421259 Helicobacter pylori P12 7011105 YP_002301982.1 CDS virD2-2 NC_011498.1 1421785 1423818 R relaxase complement(1421785..1423818) Helicobacter pylori P12 7011106 YP_002301983.1 CDS nadC NC_011498.1 1425436 1426257 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(1425436..1426257) Helicobacter pylori P12 7011107 YP_002301984.1 CDS nadA NC_011498.1 1426257 1427267 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(1426257..1427267) Helicobacter pylori P12 7011108 YP_002301985.1 CDS psd NC_011498.1 1427257 1428060 R catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase complement(1427257..1428060) Helicobacter pylori P12 7011109 YP_002301986.1 CDS HPP12_1357 NC_011498.1 1428054 1428560 R hypothetical protein complement(1428054..1428560) Helicobacter pylori P12 7011110 YP_002301987.1 CDS HPP12_1358 NC_011498.1 1428573 1429124 R hypothetical protein complement(1428573..1429124) Helicobacter pylori P12 7011111 YP_002301988.1 CDS ubiA NC_011498.1 1429060 1429944 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase complement(1429060..1429944) Helicobacter pylori P12 7011112 YP_002301989.1 CDS comE NC_011498.1 1429971 1431284 R competence locus E ComE3 complement(1429971..1431284) Helicobacter pylori P12 7011113 YP_002301990.1 CDS dnaB NC_011498.1 1431281 1432741 R unwinds double stranded DNA; replicative DNA helicase complement(1431281..1432741) Helicobacter pylori P12 7011114 YP_002301991.1 CDS HPP12_1362 NC_011498.1 1432752 1434146 R integral membrane protein complement(1432752..1434146) Helicobacter pylori P12 7011115 YP_002301992.1 CDS HPP12_1363 NC_011498.1 1434149 1435261 R histidine kinase sensor protein complement(1434149..1435261) Helicobacter pylori P12 7011116 YP_002301993.1 CDS HPP12_1364 NC_011498.1 1435317 1435958 R response regulator complement(1435317..1435958) Helicobacter pylori P12 7011117 YP_002301994.1 CDS mod-3 NC_011498.1 1436023 1438488 D type III R-M system methyltransferase 1436023..1438488 Helicobacter pylori P12 7011118 YP_002301995.1 CDS res-2 NC_011498.1 1438499 1441306 D type III R-M system restriction enzyme 1438499..1441306 Helicobacter pylori P12 7011119 YP_002301996.1 CDS mreC NC_011498.1 1441460 1442206 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(1441460..1442206) Helicobacter pylori P12 7011120 YP_002301997.1 CDS mreB NC_011498.1 1442210 1443253 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(1442210..1443253) Helicobacter pylori P12 7011121 YP_002301998.1 CDS clpX NC_011498.1 1443296 1444642 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1443296..1444642) Helicobacter pylori P12 7011122 YP_002301999.1 CDS lpxA NC_011498.1 1444644 1445456 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1444644..1445456) Helicobacter pylori P12 7011123 YP_002302000.1 CDS fabZ NC_011498.1 1445459 1445938 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1445459..1445938) Helicobacter pylori P12 7011124 YP_002302001.1 CDS fliW-2 NC_011498.1 1446119 1446508 R binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW complement(1446119..1446508) Helicobacter pylori P12 7011125 YP_002302002.1 CDS comL NC_011498.1 1446917 1447579 D competence lipoprotein ComL 1446917..1447579 Helicobacter pylori P12 7011126 YP_002302003.1 CDS lon NC_011498.1 1447621 1450125 D ATP-dependent protease Lon 1447621..1450125 Helicobacter pylori P12 7011127 YP_002302004.1 CDS tyrA NC_011498.1 1450134 1450961 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1450134..1450961 Helicobacter pylori P12 7011128 YP_002302005.1 CDS HPP12_1376 NC_011498.1 1451282 1452145 R endonuclease G complement(1451282..1452145) Helicobacter pylori P12 7011129 YP_002302006.1 CDS mod-4 NC_011498.1 1452411 1454288 R type III R-M system methyltransferase complement(1452411..1454288) Helicobacter pylori P12 7011130 YP_002302007.1 CDS bioB NC_011498.1 1457029 1457877 D catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1457029..1457877 Helicobacter pylori P12 7011132 YP_002302008.1 CDS rbn NC_011498.1 1457877 1458755 D ribonuclease N 1457877..1458755 Helicobacter pylori P12 7011133 YP_002302009.1 CDS HPP12_1381 NC_011498.1 1463709 1464203 D hypothetical protein 1463709..1464203 Helicobacter pylori P12 7011136 YP_002302010.1 CDS HPP12_1382 NC_011498.1 1464203 1465996 D hypothetical protein 1464203..1465996 Helicobacter pylori P12 7011137 YP_002302011.1 CDS HPP12_1383 NC_011498.1 1466136 1466765 D hypothetical protein 1466136..1466765 Helicobacter pylori P12 7011138 YP_002302012.1 CDS HPP12_1384 NC_011498.1 1466750 1467046 D hypothetical protein 1466750..1467046 Helicobacter pylori P12 7011139 YP_002302013.1 CDS HPP12_1385 NC_011498.1 1467164 1467610 R NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(1467164..1467610) Helicobacter pylori P12 7011140 YP_002302014.1 CDS HPP12_1386 NC_011498.1 1467670 1468011 D hypothetical protein 1467670..1468011 Helicobacter pylori P12 7011141 YP_002302015.1 CDS miaA NC_011498.1 1468082 1468906 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1468082..1468906 Helicobacter pylori P12 7011142 YP_002302016.1 CDS HPP12_1388 NC_011498.1 1468918 1470027 D lipopolysaccharide 1,2-glucosyltransferase 1468918..1470027 Helicobacter pylori P12 7011143 YP_002302017.1 CDS HPP12_1389 NC_011498.1 1470038 1471000 R type II R-M system restriction endonuclease complement(1470038..1471000) Helicobacter pylori P12 7011144 YP_002302018.1 CDS HPP12_1390 NC_011498.1 1470981 1471751 R type II R-M system restriction endonuclease complement(1470981..1471751) Helicobacter pylori P12 7011145 YP_002302019.1 CDS murB NC_011498.1 1471841 1472620 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1471841..1472620) Helicobacter pylori P12 7011146 YP_002302020.1 CDS fliQ NC_011498.1 1472624 1472890 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(1472624..1472890) Helicobacter pylori P12 7011147 YP_002302021.1 CDS fliI NC_011498.1 1472901 1474205 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(1472901..1474205) Helicobacter pylori P12 7011148 YP_002302022.1 CDS virB11-4 NC_011498.1 1474206 1475120 R type IV secretion system ATPase complement(1474206..1475120) Helicobacter pylori P12 7011149 YP_002302023.1 CDS ileS NC_011498.1 1475137 1477899 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1475137..1477899) Helicobacter pylori P12 7011150 YP_002302024.1 CDS HPP12_1396 NC_011498.1 1477924 1478178 R hypothetical protein complement(1477924..1478178) Helicobacter pylori P12 7011151 YP_002302025.1 CDS HPP12_1397 NC_011498.1 1478280 1478900 D hypothetical protein 1478280..1478900 Helicobacter pylori P12 7011152 YP_002302026.1 CDS HPP12_1398 NC_011498.1 1479129 1479917 R hypothetical protein complement(1479129..1479917) Helicobacter pylori P12 7011153 YP_002302027.1 CDS HPP12_1399 NC_011498.1 1480154 1480375 R hypothetical protein complement(1480154..1480375) Helicobacter pylori P12 7011154 YP_002302028.1 CDS HPP12_1400 NC_011498.1 1480562 1481635 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(1480562..1481635) Helicobacter pylori P12 7011155 YP_002302029.1 CDS HPP12_1401 NC_011498.1 1481632 1482621 R polysialic acid capsule expression protein complement(1481632..1482621) Helicobacter pylori P12 7011156 YP_002302030.1 CDS HPP12_1402 NC_011498.1 1482605 1484680 R ATP/GTP binding protein complement(1482605..1484680) Helicobacter pylori P12 7011157 YP_002302031.1 CDS ksgA NC_011498.1 1484718 1485533 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1484718..1485533) Helicobacter pylori P12 7011158 YP_002302032.1 CDS HPP12_1404 NC_011498.1 1485796 1486032 D histidine and glutamine-rich metal binding protein 1485796..1486032 Helicobacter pylori P12 7011159 YP_002302033.1 CDS HPP12_1405 NC_011498.1 1485806 1486078 D hypothetical protein 1485806..1486078 Helicobacter pylori P12 7011160 YP_002302034.1 CDS HPP12_1406 NC_011498.1 1486320 1486451 D hypothetical protein 1486320..1486451 Helicobacter pylori P12 7011161 YP_002302035.1 CDS HPP12_1407 NC_011498.1 1486667 1487452 R hypothetical protein complement(1486667..1487452) Helicobacter pylori P12 7011162 YP_002302036.1 CDS HPP12_1408 NC_011498.1 1487452 1489119 R hypothetical protein complement(1487452..1489119) Helicobacter pylori P12 7011163 YP_002302037.1 CDS purU NC_011498.1 1489120 1490001 R formyltetrahydrofolate hydrolase complement(1489120..1490001) Helicobacter pylori P12 7011164 YP_002302038.1 CDS sppA NC_011498.1 1490004 1490882 R signal peptide protease IV complement(1490004..1490882) Helicobacter pylori P12 7011165 YP_002302039.1 CDS HPP12_1411 NC_011498.1 1490953 1491225 D hypothetical protein 1490953..1491225 Helicobacter pylori P12 7011166 YP_002302040.1 CDS HPP12_1412 NC_011498.1 1491430 1491636 D hypothetical protein 1491430..1491636 Helicobacter pylori P12 7011167 YP_002302041.1 CDS HPP12_1413 NC_011498.1 1491623 1492150 D hypothetical protein 1491623..1492150 Helicobacter pylori P12 7011168 YP_002302042.1 CDS HPP12_1414 NC_011498.1 1492159 1492494 D hypothetical protein 1492159..1492494 Helicobacter pylori P12 7011169 YP_002302043.1 CDS HPP12_1415 NC_011498.1 1492527 1492652 D hypothetical protein 1492527..1492652 Helicobacter pylori P12 7011170 YP_002302044.1 CDS HPP12_1416 NC_011498.1 1492663 1492809 D hypothetical protein 1492663..1492809 Helicobacter pylori P12 7011171 YP_002302045.1 CDS HPP12_1417 NC_011498.1 1492790 1493122 D hypothetical protein 1492790..1493122 Helicobacter pylori P12 7011172 YP_002302046.1 CDS HPP12_1418 NC_011498.1 1496425 1497060 R hypothetical protein complement(1496425..1497060) Helicobacter pylori P12 7011174 YP_002302047.1 CDS ppiA NC_011498.1 1497329 1497817 D peptidyl-prolyl cis-trans isomerase B 1497329..1497817 Helicobacter pylori P12 7011175 YP_002302048.1 CDS csrA NC_011498.1 1497836 1498066 D affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator 1497836..1498066 Helicobacter pylori P12 7011176 YP_002302049.1 CDS HPP12_1421 NC_011498.1 1498067 1498870 D catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1498067..1498870 Helicobacter pylori P12 7011177 YP_002302050.1 CDS smpB NC_011498.1 1498867 1499325 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1498867..1499325 Helicobacter pylori P12 7011178 YP_002302051.1 CDS exbB-3 NC_011498.1 1499328 1499780 D biopolymer transport protein ExbB 1499328..1499780 Helicobacter pylori P12 7011179 YP_002302052.1 CDS exbD-3 NC_011498.1 1499791 1500192 D biopolymer transport protein ExbD 1499791..1500192 Helicobacter pylori P12 7011180 YP_002302053.1 CDS rnpA NC_011498.1 1500358 1500843 D ribonuclease P protein component 1500358..1500843 Helicobacter pylori P12 7011181 YP_002302054.1 CDS HPP12_1426 NC_011498.1 1500830 1501186 D hypothetical protein 1500830..1501186 Helicobacter pylori P12 7011182 YP_002302055.1 CDS yidC NC_011498.1 1501192 1502832 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 1501192..1502832 Helicobacter pylori P12 7011183 YP_002302056.1 CDS HPP12_1428 NC_011498.1 1502832 1503626 D VirB11-interacting protein 1502832..1503626 Helicobacter pylori P12 7011184 YP_002302057.1 CDS trmE NC_011498.1 1503586 1504971 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1503586..1504971 Helicobacter pylori P12 7011185 YP_002302058.1 CDS homD NC_011498.1 1505177 1507417 D outer membrane protein HomD 1505177..1507417 Helicobacter pylori P12 7011186 YP_002302059.1 CDS HPP12_1431 NC_011498.1 1507434 1507625 R hypothetical protein complement(1507434..1507625) Helicobacter pylori P12 7011187 YP_002302060.1 CDS HPP12_1432 NC_011498.1 1508237 1509148 R hypothetical protein complement(1508237..1509148) Helicobacter pylori P12 7011188 YP_002302061.1 CDS HPP12_1433 NC_011498.1 1509158 1509499 R hypothetical protein complement(1509158..1509499) Helicobacter pylori P12 7011189 YP_002302062.1 CDS HPP12_1434 NC_011498.1 1509507 1510034 R membrane-associated lipoprotein complement(1509507..1510034) Helicobacter pylori P12 7011190 YP_002302063.1 CDS HPP12_1435 NC_011498.1 1510058 1510690 R hypothetical protein complement(1510058..1510690) Helicobacter pylori P12 7011191 YP_002302064.1 CDS HPP12_1436 NC_011498.1 1511106 1511420 R thioredoxin complement(1511106..1511420) Helicobacter pylori P12 7011192 YP_002302065.1 CDS HPP12_1437 NC_011498.1 1511475 1512263 R ribosomal large subunit pseudouridine synthase B complement(1511475..1512263) Helicobacter pylori P12 7011193 YP_002302066.1 CDS dnaE NC_011498.1 1512245 1515880 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(1512245..1515880) Helicobacter pylori P12 7011194 YP_002302067.1 CDS HPP12_1439 NC_011498.1 1516028 1517080 D cytochrome C551 peroxidase 1516028..1517080 Helicobacter pylori P12 7011195 YP_002302068.1 CDS HPP12_1440 NC_011498.1 1517259 1517846 R secreted motility protein complement(1517259..1517846) Helicobacter pylori P12 7011196 YP_002302069.1 CDS HPP12_1441 NC_011498.1 1517863 1518540 R hypothetical protein complement(1517863..1518540) Helicobacter pylori P12 7011197 YP_002302070.1 CDS HPP12_1442 NC_011498.1 1518543 1519358 R ABC transporter substrate binding protein complement(1518543..1519358) Helicobacter pylori P12 7011198 YP_002302071.1 CDS HPP12_1443 NC_011498.1 1519343 1520128 R ABC transporter ATP-binding protein complement(1519343..1520128) Helicobacter pylori P12 7011199 YP_002302072.1 CDS HPP12_1444 NC_011498.1 1520128 1521261 R ABC transporter permease protein complement(1520128..1521261) Helicobacter pylori P12 7011200 YP_002302073.1 CDS HPP12_1445 NC_011498.1 1521395 1522090 D outer membrane protein 1521395..1522090 Helicobacter pylori P12 7011201 YP_002302074.1 CDS ilvE NC_011498.1 1522095 1523117 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1522095..1523117) Helicobacter pylori P12 7011202 YP_002302075.1 CDS horJ NC_011498.1 1523166 1523912 R outer membrane protein HorJ complement(1523166..1523912) Helicobacter pylori P12 7011203 YP_002302076.1 CDS polA NC_011498.1 1524027 1526738 R DNA polymerase I complement(1524027..1526738) Helicobacter pylori P12 7011204 YP_002302077.1 CDS HPP12_1449 NC_011498.1 1526804 1528045 R type IIS R-M system restriction enzyme complement(1526804..1528045) Helicobacter pylori P12 7011205 YP_002302078.1 CDS HPP12_1450 NC_011498.1 1528042 1530078 R type IIS R-M system methyltransferase complement(1528042..1530078) Helicobacter pylori P12 7011206 YP_002302079.1 CDS HPP12_1451 NC_011498.1 1530112 1530687 R amidophosphoribosyltransferase complement(1530112..1530687) Helicobacter pylori P12 7011207 YP_002302080.1 CDS tmk NC_011498.1 1530675 1531250 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1530675..1531250) Helicobacter pylori P12 7011208 YP_002302081.1 CDS coaD NC_011498.1 1531252 1531725 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1531252..1531725) Helicobacter pylori P12 7011209 YP_002302082.1 CDS ubiD NC_011498.1 1531725 1532288 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1531725..1532288) Helicobacter pylori P12 7011210 YP_002302083.1 CDS flgA NC_011498.1 1532298 1532954 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1532298..1532954) Helicobacter pylori P12 7011211 YP_002302084.1 CDS HPP12_1456 NC_011498.1 1532951 1534996 R DNA helicase II complement(1532951..1534996) Helicobacter pylori P12 7011212 YP_002302085.1 CDS HPP12_1457 NC_011498.1 1534996 1537530 R hypothetical protein complement(1534996..1537530) Helicobacter pylori P12 7011213 YP_002302086.1 CDS serS NC_011498.1 1537540 1538787 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(1537540..1538787) Helicobacter pylori P12 7011214 YP_002302087.1 CDS HPP12_1459 NC_011498.1 1538788 1539585 R hypothetical protein complement(1538788..1539585) Helicobacter pylori P12 7011215 YP_002302088.1 CDS HPP12_1460 NC_011498.1 1539589 1539840 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1539589..1539840) Helicobacter pylori P12 7011216 YP_002302089.1 CDS ubiE NC_011498.1 1539850 1540590 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(1539850..1540590) Helicobacter pylori P12 7011217 YP_002302090.1 CDS HPP12_1462 NC_011498.1 1540617 1541063 R integral membrane protein complement(1540617..1541063) Helicobacter pylori P12 7011218 YP_002302091.1 CDS HPP12_1463 NC_011498.1 1541074 1541646 R hypothetical protein complement(1541074..1541646) Helicobacter pylori P12 7011219 YP_002302092.1 CDS HPP12_1464 NC_011498.1 1541633 1542763 R ABC-2 type transport system permease protein complement(1541633..1542763) Helicobacter pylori P12 7011220 YP_002302093.1 CDS HPP12_1465 NC_011498.1 1542760 1543857 R ABC-2 type transport system permease protein complement(1542760..1543857) Helicobacter pylori P12 7011221 YP_002302094.1 CDS HPP12_1466 NC_011498.1 1543869 1544858 R secreted protein complement(1543869..1544858) Helicobacter pylori P12 7011222 YP_002302095.1 CDS HPP12_1467 NC_011498.1 1544870 1546402 R outer membrane efflux protein complement(1544870..1546402) Helicobacter pylori P12 7011223 YP_002302096.1 CDS HPP12_1468 NC_011498.1 1546418 1547755 R integral membrane protein; hemolysin domain-containing protein complement(1546418..1547755) Helicobacter pylori P12 7011224 YP_002302097.1 CDS HPP12_1469 NC_011498.1 1547858 1549459 R phosphate permease complement(1547858..1549459) Helicobacter pylori P12 7011225 YP_002302098.1 CDS HPP12_1470 NC_011498.1 1549600 1549869 D nifu-like protein 1549600..1549869 Helicobacter pylori P12 7011226 YP_002302099.1 CDS HPP12_1471 NC_011498.1 1549881 1550492 D hypothetical protein 1549881..1550492 Helicobacter pylori P12 7011227 YP_002302100.1 CDS murE NC_011498.1 1550496 1551839 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1550496..1551839 Helicobacter pylori P12 7011228 YP_002302101.1 CDS tal NC_011498.1 1551842 1552792 D Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1551842..1552792 Helicobacter pylori P12 7011229 YP_002302102.1 CDS rplY NC_011498.1 1552847 1553383 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1552847..1553383 Helicobacter pylori P12 7011230 YP_002302103.1 CDS pth NC_011498.1 1553393 1553953 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1553393..1553953 Helicobacter pylori P12 7011231 YP_002302104.1 CDS HPP12_1476 NC_011498.1 1553963 1555030 D hypothetical protein 1553963..1555030 Helicobacter pylori P12 7011232 YP_002302105.1 CDS HPP12_1477 NC_011498.1 1555145 1556065 D hypothetical protein 1555145..1556065 Helicobacter pylori P12 7011233 YP_002302106.1 CDS HPP12_1478 NC_011498.1 1556142 1557437 D restriction endonuclease 1556142..1557437 Helicobacter pylori P12 7011234 YP_002302107.1 CDS horK NC_011498.1 1557615 1558781 R outer membrane protein HorK complement(1557615..1558781) Helicobacter pylori P12 7011235 YP_002302108.1 CDS HPP12_1480 NC_011498.1 1558961 1559398 D hypothetical protein 1558961..1559398 Helicobacter pylori P12 7011236 YP_002302109.1 CDS fixI NC_011498.1 1559395 1561746 R cation transporting P-type ATPase complement(1559395..1561746) Helicobacter pylori P12 7011237 YP_002302110.1 CDS HPP12_1482 NC_011498.1 1561771 1562487 R hypothetical protein complement(1561771..1562487) Helicobacter pylori P12 7011238 YP_002302111.1 CDS HPP12_1483 NC_011498.1 1562469 1563503 R riboflavin biosynthesis protein complement(1562469..1563503) Helicobacter pylori P12 7011239 YP_002302112.1 CDS gltS NC_011498.1 1563500 1564726 R sodium/glutamate symport carrier protein complement(1563500..1564726) Helicobacter pylori P12 7011240 YP_002302113.1 CDS HPP12_1485 NC_011498.1 1564812 1566011 D saccharopine dehydrogenase 1564812..1566011 Helicobacter pylori P12 7011241 YP_002302114.1 CDS HPP12_1486 NC_011498.1 1566021 1567397 R ferredoxin-like protein complement(1566021..1567397) Helicobacter pylori P12 7011242 YP_002302115.1 CDS HPP12_1487 NC_011498.1 1567377 1568165 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 1567377..1568165 Helicobacter pylori P12 7011243 YP_002302116.1 CDS folB NC_011498.1 1568162 1568515 D dihydroneopterin aldolase 1568162..1568515 Helicobacter pylori P12 7011244 YP_002302117.1 CDS HPP12_1489 NC_011498.1 1568499 1568825 D frpb-like protein 1568499..1568825 Helicobacter pylori P12 7011245 YP_002302118.1 CDS frpB-4 NC_011498.1 1568979 1571612 D iron-regulated outer membrane protein 1568979..1571612 Helicobacter pylori P12 7011246 YP_002302119.1 CDS selA NC_011498.1 1571840 1573012 D catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1571840..1573012 Helicobacter pylori P12 7011247 YP_002302120.1 CDS nusA NC_011498.1 1573109 1574296 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1573109..1574296 Helicobacter pylori P12 7011248 YP_002302121.1 CDS HPP12_1493 NC_011498.1 1574353 1574847 D hypothetical protein 1574353..1574847 Helicobacter pylori P12 7011249 YP_002302122.1 CDS HPP12_1494 NC_011498.1 1575820 1579728 R type IIS R-M system restriction/modification enzyme complement(1575820..1579728) Helicobacter pylori P12 7011250 YP_002302123.1 CDS HPP12_1495 NC_011498.1 1580020 1582023 R hypothetical protein complement(1580020..1582023) Helicobacter pylori P12 7011251 YP_002302124.1 CDS res-4 NC_011498.1 1582157 1585066 R type III R-M system restriction enzyme complement(1582157..1585066) Helicobacter pylori P12 7011252 YP_002302125.1 CDS mod-5 NC_011498.1 1585069 1587111 R type III R-M system methyltransferase complement(1585069..1587111) Helicobacter pylori P12 7011253 YP_002302126.1 CDS recG NC_011498.1 1587160 1589031 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1587160..1589031) Helicobacter pylori P12 7011254 YP_002302127.1 CDS HPP12_1499 NC_011498.1 1589113 1589460 D hypothetical protein 1589113..1589460 Helicobacter pylori P12 7011255 YP_002302128.1 CDS HPP12_1500 NC_011498.1 1589464 1590099 D hypothetical protein 1589464..1590099 Helicobacter pylori P12 7011256 YP_002302129.1 CDS exoA NC_011498.1 1590096 1590848 R AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III complement(1590096..1590848) Helicobacter pylori P12 7011257 YP_002302130.1 CDS HPP12_1502 NC_011498.1 1591028 1592458 R periplasmic competence protein comh complement(1591028..1592458) Helicobacter pylori P12 7011259 YP_002302131.1 CDS dnaA NC_011498.1 1592687 1594054 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(1592687..1594054) Helicobacter pylori P12 7011260 YP_002302132.1 CDS HPP12_1504 NC_011498.1 1594207 1594749 D purine nucleoside phosphorylase 1594207..1594749 Helicobacter pylori P12 7011261 YP_002302133.1 CDS HPP12_1505 NC_011498.1 1594792 1595031 D hypothetical protein 1594792..1595031 Helicobacter pylori P12 7011262 YP_002302134.1 CDS glmS NC_011498.1 1595032 1596825 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1595032..1596825 Helicobacter pylori P12 7011263 YP_002302135.1 CDS thyX NC_011498.1 1596847 1597479 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1596847..1597479 Helicobacter pylori P12 7011264 YP_002302136.1 CDS hsdS-4 NC_011498.1 1598131 1599339 R type I R-M system S protein complement(1598131..1599339) Helicobacter pylori P12 7011265 YP_002302137.1 CDS hsdM-3 NC_011498.1 1599336 1601786 R type I R-M system M protein complement(1599336..1601786) Helicobacter pylori P12 7011266 YP_002302138.1 CDS HPP12_1511 NC_011498.1 1604830 1605537 D hypothetical protein 1604830..1605537 Helicobacter pylori P12 7011268 YP_002302139.1 CDS rocF NC_011498.1 1608504 1609472 R arginase complement(1608504..1609472) Helicobacter pylori P12 7011270 YP_002302140.1 CDS ald NC_011498.1 1609676 1610818 D alanine dehydrogenase 1609676..1610818 Helicobacter pylori P12 7011271 YP_002302141.1 CDS HPP12_1515 NC_011498.1 1610933 1611604 D hypothetical protein 1610933..1611604 Helicobacter pylori P12 7011272 YP_002302142.1 CDS HPP12_1516 NC_011498.1 1611582 1612331 D hypothetical protein 1611582..1612331 Helicobacter pylori P12 7011273 YP_002302143.1 CDS HPP12_1517 NC_011498.1 1612482 1612661 D hypothetical protein 1612482..1612661 Helicobacter pylori P12 7011274 YP_002302144.1 CDS horL NC_011498.1 1612672 1613400 R outer membrane protein HorL complement(1612672..1613400) Helicobacter pylori P12 7011275 YP_002302145.1 CDS HPP12_1519 NC_011498.1 1613587 1614441 D inorganic polyphosphate/ATP-NAD kinase 1613587..1614441 Helicobacter pylori P12 7011276 YP_002302146.1 CDS recN NC_011498.1 1614458 1616032 D DNA repair protein RecN 1614458..1616032 Helicobacter pylori P12 7011277 YP_002302147.1 CDS HPP12_1521 NC_011498.1 1616029 1617336 D fibronectin/fibrinogen-binding protein 1616029..1617336 Helicobacter pylori P12 7011278 YP_002302148.1 CDS HPP12_1522 NC_011498.1 1617355 1617651 D hypothetical protein 1617355..1617651 Helicobacter pylori P12 7011279 YP_002302149.1 CDS HPP12_1523 NC_011498.1 1617938 1618852 R type II R-M system methyltransferase complement(1617938..1618852) Helicobacter pylori P12 7011280 YP_002302150.1 CDS HPP12_1524 NC_011498.1 1618865 1619068 R hypothetical protein complement(1618865..1619068) Helicobacter pylori P12 7011281 YP_002302151.1 CDS fbp NC_011498.1 1619068 1619940 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(1619068..1619940) Helicobacter pylori P12 7011282 YP_002302152.1 CDS rpe NC_011498.1 1620011 1620664 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1620011..1620664 Helicobacter pylori P12 7011283 YP_002302153.1 CDS HPP12_1527 NC_011498.1 1620534 1621505 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1620534..1621505 Helicobacter pylori P12 7011284 YP_002302154.1 CDS HPP12_1528 NC_011498.1 1621688 1622248 R hypothetical protein complement(1621688..1622248) Helicobacter pylori P12 7011285 YP_002302155.1 CDS tsf NC_011498.1 1622491 1623558 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1622491..1623558) Helicobacter pylori P12 7011286 YP_002302156.1 CDS rpsB NC_011498.1 1623558 1624352 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1623558..1624352) Helicobacter pylori P12 7011287 YP_002302157.1 CDS pcrA NC_011498.1 1624603 1627443 D putative recombination protein RecB 1624603..1627443 Helicobacter pylori P12 7011288 YP_002302158.1 CDS nhaA NC_011498.1 1627467 1628783 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1627467..1628783 Helicobacter pylori P12 7011289 YP_002302159.1 CDS yajC NC_011498.1 1628831 1629214 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1628831..1629214 Helicobacter pylori P12 7011290 YP_002302160.1 CDS secD NC_011498.1 1629211 1630788 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1629211..1630788 Helicobacter pylori P12 7011291 YP_002302161.1 CDS secF NC_011498.1 1630797 1631768 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1630797..1631768 Helicobacter pylori P12 7011292 YP_002302162.1 CDS HPP12_1536 NC_011498.1 1631778 1632116 D integral membrane protein 1631778..1632116 Helicobacter pylori P12 7011293 YP_002302163.1 CDS leuS NC_011498.1 1632126 1634546 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1632126..1634546 Helicobacter pylori P12 7011294 YP_002302164.1 CDS HPP12_1538 NC_011498.1 1634543 1635055 D hypothetical protein 1634543..1635055 Helicobacter pylori P12 7011295 YP_002302165.1 CDS folC NC_011498.1 1635045 1636214 D bifunctional folylpolyglutamate synthase / dihydrofolate synthase 1635045..1636214 Helicobacter pylori P12 7011296 YP_002302166.1 CDS HPP12_1540 NC_011498.1 1636214 1637140 D membrane-bound metallopeptidase 1636214..1637140 Helicobacter pylori P12 7011297 YP_002302167.1 CDS HPP12_1541 NC_011498.1 1637149 1638084 D membrane-bound metallopeptidase 1637149..1638084 Helicobacter pylori P12 7011298 YP_002302168.1 CDS HPP12_1542 NC_011498.1 1638003 1638413 D hypothetical protein 1638003..1638413 Helicobacter pylori P12 7011299 YP_002302169.1 CDS mfd NC_011498.1 1638417 1641416 D transcription-repair coupling factor 1638417..1641416 Helicobacter pylori P12 7011300 YP_002302170.1 CDS petA NC_011498.1 1641542 1642045 D ubiquinol cytochrome C oxidoreductase rieske 2Fe-2S subunit 1641542..1642045 Helicobacter pylori P12 7011301 YP_002302171.1 CDS HPP12_1545 NC_011498.1 1642056 1643294 D ubiquinol cytochrome C oxidoreductase cytochrome B subunit 1642056..1643294 Helicobacter pylori P12 7011302 YP_002302172.1 CDS HPP12_1546 NC_011498.1 1643291 1644148 D ubiquinol cytochrome C oxidoreductase cytochrome C1 1643291..1644148 Helicobacter pylori P12 7011303 YP_002302173.1 CDS HPP12_1547 NC_011498.1 1644558 1645658 R hypothetical protein complement(1644558..1645658) Helicobacter pylori P12 7011304 YP_002302174.1 CDS ftsI NC_011498.1 1645987 1647834 R penicillin-binding protein; cell division protein FtsI complement(1645987..1647834) Helicobacter pylori P12 7011305 YP_002302175.1 CDS fliE NC_011498.1 1647990 1648319 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1647990..1648319) Helicobacter pylori P12 7011306 YP_002302176.1 CDS flgC NC_011498.1 1648447 1648932 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(1648447..1648932) Helicobacter pylori P12 7011307 YP_002302177.1 CDS flgB NC_011498.1 1648945 1649367 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB complement(1648945..1649367) Helicobacter pylori P12 7011308 YP_002302178.1 CDS ftsW NC_011498.1 1649576 1650742 D cell division protein FtsW 1649576..1650742 Helicobacter pylori P12 7011309 YP_002302179.1 CDS HPP12_1553 NC_011498.1 1650766 1651767 R iron(III) ABC transporter periplasmic iron-binding protein complement(1650766..1651767) Helicobacter pylori P12 7011310 YP_002302180.1 CDS HPP12_1554 NC_011498.1 1652007 1652603 D alkyl hydroperoxide reductase 1652007..1652603 Helicobacter pylori P12 7011311 YP_002302181.1 CDS HPP12_1555 NC_011498.1 1652751 1653566 D outer membrane lipoprotein 1652751..1653566 Helicobacter pylori P12 7011312 YP_002302182.1 CDS pbp2 NC_011498.1 1654038 1655804 R penicillin-binding protein 2 complement(1654038..1655804) Helicobacter pylori P12 7011313 YP_002302183.1 CDS HPP12_1557 NC_011498.1 1655801 1656229 R hypothetical protein complement(1655801..1656229) Helicobacter pylori P12 7011314 YP_002302184.1 CDS engB NC_011498.1 1656241 1656867 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1656241..1656867) Helicobacter pylori P12 7011315 YP_002302185.1 CDS HPP12_1559 NC_011498.1 1656864 1657421 R hypothetical protein complement(1656864..1657421) Helicobacter pylori P12 7011316 YP_002302186.1 CDS HPP12_1560 NC_011498.1 1657421 1658014 R hypothetical protein complement(1657421..1658014) Helicobacter pylori P12 7011317 YP_002302187.1 CDS HPP12_1561 NC_011498.1 1657989 1658483 R ABC transporter inner membrane protein complement(1657989..1658483) Helicobacter pylori P12 7011318 YP_002302188.1 CDS rlpA NC_011498.1 1658480 1659424 R rare lipoprotein A complement(1658480..1659424) Helicobacter pylori P12 7011319 YP_002302189.1 CDS dniR NC_011498.1 1659424 1660542 R regulatory protein DniR complement(1659424..1660542) Helicobacter pylori P12 7011320 YP_002302190.1 CDS HPP12_1564 NC_011498.1 1660630 1661394 R DNAse of the TatD family complement(1660630..1661394) Helicobacter pylori P12 7011321 YP_002302191.1 CDS ribC NC_011498.1 1661469 1662089 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1661469..1662089 Helicobacter pylori P12 7011322 YP_002302192.1 CDS flhB-2 NC_011498.1 1662090 1662362 D FlhB-related flagellar biosynthesis protein 1662090..1662362 Helicobacter pylori P12 7011323 YP_002302193.1 CDS metN NC_011498.1 1662384 1663367 D part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 1662384..1663367 Helicobacter pylori P12 7011324 YP_002302194.1 CDS HPP12_1568 NC_011498.1 1663369 1664016 D ABC transporter permease protein 1663369..1664016 Helicobacter pylori P12 7011325 YP_002302195.1 CDS HPP12_1569 NC_011498.1 1664048 1665166 R lps biosynthesis protein complement(1664048..1665166) Helicobacter pylori P12 7011326 YP_002302196.1 CDS HPP12_1570 NC_011498.1 1665215 1665643 R hypothetical protein complement(1665215..1665643) Helicobacter pylori P12 7011327 YP_002302197.1 CDS HPP12_1571 NC_011498.1 1665653 1666315 R hypothetical protein complement(1665653..1666315) Helicobacter pylori P12 7011328 YP_002302198.1 CDS HPP12_1572 NC_011498.1 1666246 1667256 R undecaprenyl phosphate N-acetylglucosaminyltransferase complement(1666246..1667256) Helicobacter pylori P12 7011329 YP_002302199.1 CDS pdxJ NC_011498.1 1667383 1668171 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1667383..1668171 Helicobacter pylori P12 7011330 YP_002302200.1 CDS pdxA NC_011498.1 1668173 1669096 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1668173..1669096 Helicobacter pylori P12 7011331 YP_002302201.1 CDS ydiE NC_011498.1 1669161 1670183 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1669161..1670183 Helicobacter pylori P12 7011332 YP_002302202.1 CDS flgG NC_011498.1 1670362 1671150 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1670362..1671150 Helicobacter pylori P12 7011333 YP_002302203.1 CDS HPP12_1577 NC_011498.1 1671249 1671395 R hypothetical protein complement(1671249..1671395) Helicobacter pylori P12 7011334 YP_002302204.1 CDS HPP12_1578 NC_011498.1 1671626 1671973 R hypothetical protein complement(1671626..1671973) Helicobacter pylori P12 7011335 YP_002302205.1 CDS HPP12_1579 NC_011498.1 1671942 1672175 R hypothetical protein complement(1671942..1672175) Helicobacter pylori P12 7011336 YP_002302206.1 CDS HPP12_1580 NC_011498.1 1672526 1672666 R hypothetical protein complement(1672526..1672666) Helicobacter pylori P12 7011337 YP_002302207.1 CDS HPP12_1581 NC_011498.1 1672752 1673513 R hypothetical protein complement(1672752..1673513) Helicobacter pylori P12 7011338 YP_002302208.1 CDS HPP12_p01 NC_011499.1 8 1171 R MccC complement(8..1171) Helicobacter pylori P12 7011351 YP_002302209.1 CDS HPP12_p02 NC_011499.1 1183 2235 R MccB complement(1183..2235) Helicobacter pylori P12 7011341 YP_002302211.1 CDS HPP12_p04 NC_011499.1 2515 4497 R relaxase complement(2515..4497) Helicobacter pylori P12 7011343 YP_002302212.1 CDS HPP12_p05 NC_011499.1 2553 3254 R MobD complement(2553..3254) Helicobacter pylori P12 7011344 YP_002302213.1 CDS HPP12_p06 NC_011499.1 3264 3794 R MobB complement(3264..3794) Helicobacter pylori P12 7011345 YP_002302214.1 CDS HPP12_p07 NC_011499.1 4487 4831 R MobC complement(4487..4831) Helicobacter pylori P12 7011346 YP_002302215.1 CDS HPP12_p08 NC_011499.1 5026 5307 D hypothetical protein 5026..5307 Helicobacter pylori P12 7011347 YP_002302216.1 CDS HPP12_p09 NC_011499.1 5316 5585 D hypothetical protein 5316..5585 Helicobacter pylori P12 7011348 YP_002302217.1 CDS HPP12_p10 NC_011499.1 7531 9129 D RepA 7531..9129 Helicobacter pylori P12 7011349 YP_002302218.1 CDS HPP12_p11 NC_011499.1 9171 9908 D Fic family protein 9171..9908 Helicobacter pylori P12 7011350 HPP12_t01 tRNA HPP12_t01 NC_011498.1 4043 4118 R tRNA-Glu complement(4043..4118) Helicobacter pylori P12 7010370 HPP12_t02 tRNA HPP12_t02 NC_011498.1 4181 4257 R tRNA-Asp complement(4181..4257) Helicobacter pylori P12 7010371 HPP12_t03 tRNA HPP12_t03 NC_011498.1 4298 4373 R tRNA-Val complement(4298..4373) Helicobacter pylori P12 7010372 HPP12_t04 tRNA HPP12_t04 NC_011498.1 4415 4489 R tRNA-Glu complement(4415..4489) Helicobacter pylori P12 7010373 HPP12_t05 tRNA HPP12_t05 NC_011498.1 4500 4575 R tRNA-Lys complement(4500..4575) Helicobacter pylori P12 7010374 HPP12_t06 tRNA HPP12_t06 NC_011498.1 77883 77958 R tRNA-Val complement(77883..77958) Helicobacter pylori P12 7010446 HPP12_t07 tRNA HPP12_t07 NC_011498.1 96068 96159 D tRNA-Ser 96068..96159 Helicobacter pylori P12 7010463 HPP12_t08 tRNA HPP12_t08 NC_011498.1 235498 235572 R tRNA-Asn complement(235498..235572) Helicobacter pylori P12 7010599 HPP12_t09 tRNA HPP12_t09 NC_011498.1 258507 258582 R tRNA-Ala complement(258507..258582) Helicobacter pylori P12 7010623 HPP12_t10 tRNA HPP12_t10 NC_011498.1 341564 341640 D tRNA-Arg 341564..341640 Helicobacter pylori P12 7010700 HPP12_t11 tRNA HPP12_t11 NC_011498.1 394327 394414 R tRNA-Ser complement(394327..394414) Helicobacter pylori P12 7010752 HPP12_t12 tRNA HPP12_t12 NC_011498.1 447437 447514 R tRNA-Pro complement(447437..447514) Helicobacter pylori P12 7010808 HPP12_t13 tRNA HPP12_t13 NC_011498.1 805564 805640 R tRNA-Met complement(805564..805640) Helicobacter pylori P12 7009886 HPP12_t14 tRNA HPP12_t14 NC_011498.1 894329 894405 D tRNA-Arg 894329..894405 Helicobacter pylori P12 7009978 HPP12_t15 tRNA HPP12_t15 NC_011498.1 947054 947130 R tRNA-Met complement(947054..947130) Helicobacter pylori P12 7010028 HPP12_t16 tRNA HPP12_t16 NC_011498.1 947153 947227 R tRNA-Gln complement(947153..947227) Helicobacter pylori P12 7010030 HPP12_t17 tRNA HPP12_t17 NC_011498.1 1002776 1002850 D tRNA-Gly 1002776..1002850 Helicobacter pylori P12 7010080 HPP12_t18 tRNA HPP12_t18 NC_011498.1 1002892 1002978 D tRNA-Leu 1002892..1002978 Helicobacter pylori P12 7010081 HPP12_t19 tRNA HPP12_t19 NC_011498.1 1003052 1003126 D tRNA-Cys 1003052..1003126 Helicobacter pylori P12 7010082 HPP12_t20 tRNA HPP12_t20 NC_011498.1 1003176 1003263 D tRNA-Ser 1003176..1003263 Helicobacter pylori P12 7010083 HPP12_t21 tRNA HPP12_t21 NC_011498.1 1075570 1075646 R tRNA-Arg complement(1075570..1075646) Helicobacter pylori P12 7010154 HPP12_t22 tRNA HPP12_t22 NC_011498.1 1075664 1075740 R tRNA-Arg complement(1075664..1075740) Helicobacter pylori P12 7010155 HPP12_t23 tRNA HPP12_t23 NC_011498.1 1075801 1075877 R tRNA-His complement(1075801..1075877) Helicobacter pylori P12 7010156 HPP12_t24 tRNA HPP12_t24 NC_011498.1 1075945 1076022 R tRNA-Pro complement(1075945..1076022) Helicobacter pylori P12 7010157 HPP12_t25 tRNA HPP12_t25 NC_011498.1 1125831 1125915 R tRNA-Leu complement(1125831..1125915) Helicobacter pylori P12 7010204 HPP12_t26 tRNA HPP12_t26 NC_011498.1 1130700 1130776 D tRNA-Ile 1130700..1130776 Helicobacter pylori P12 7010210 HPP12_t27 tRNA HPP12_t27 NC_011498.1 1130794 1130869 D tRNA-Ala 1130794..1130869 Helicobacter pylori P12 7010211 HPP12_t28 tRNA HPP12_t28 NC_011498.1 1225239 1225316 R tRNA-Met complement(1225239..1225316) Helicobacter pylori P12 7010298 HPP12_t29 tRNA HPP12_t29 NC_011498.1 1256480 1256555 R tRNA-Trp complement(1256480..1256555) Helicobacter pylori P12 7010323 HPP12_t30 tRNA HPP12_t30 NC_011498.1 1258113 1258187 R tRNA-Thr complement(1258113..1258187) Helicobacter pylori P12 7010325 HPP12_t31 tRNA HPP12_t31 NC_011498.1 1258218 1258294 R tRNA-Gly complement(1258218..1258294) Helicobacter pylori P12 7010326 HPP12_t32 tRNA HPP12_t32 NC_011498.1 1258310 1258394 R tRNA-Tyr complement(1258310..1258394) Helicobacter pylori P12 7010327 HPP12_t33 tRNA HPP12_t33 NC_011498.1 1258422 1258497 R tRNA-Thr complement(1258422..1258497) Helicobacter pylori P12 7010328 HPP12_t34 tRNA HPP12_t34 NC_011498.1 1263894 1263980 R tRNA-Leu complement(1263894..1263980) Helicobacter pylori P12 7010335 HPP12_t35 tRNA HPP12_t35 NC_011498.1 1264034 1264120 R tRNA-Leu complement(1264034..1264120) Helicobacter pylori P12 7010336 HPP12_t36 tRNA HPP12_t36 NC_011498.1 1590950 1591025 D tRNA-Phe 1590950..1591025 Helicobacter pylori P12 7011258 HPP12_r1 rRNA HPP12_r1 NC_011498.1 1054272 1054387 R 5S ribosomal RNA complement(1054272..1054387) Helicobacter pylori P12 7010137 HPP12_r2 rRNA HPP12_r2 NC_011498.1 1054627 1057512 R 23S ribosomal RNA complement(1054627..1057512) Helicobacter pylori P12 7010138 HPP12_r3 rRNA HPP12_r3 NC_011498.1 1183413 1184904 R 16S ribosomal RNA complement(1183413..1184904) Helicobacter pylori P12 7010262 HPP12_r4 rRNA HPP12_r4 NC_011498.1 1459378 1459493 R 5S ribosomal RNA complement(1459378..1459493) Helicobacter pylori P12 7011134 HPP12_r5 rRNA HPP12_r5 NC_011498.1 1459733 1462618 R 23S ribosomal RNA complement(1459733..1462618) Helicobacter pylori P12 7011135 HPP12_r6 rRNA HPP12_r6 NC_011498.1 1494436 1495927 R 16S ribosomal RNA complement(1494436..1495927) Helicobacter pylori P12 7011173